locus-tag	class	description
MKS87_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKS87_00010	COG0592	DNA-directed DNA polymerase activity
MKS87_00015	COG2501	S4 domain
MKS87_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKS87_00030	COG0187	DNA topoisomerase II activity
MKS87_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKS87_00070	COG0516	GMP reductase activity
MKS87_00070	COG0517	IMP dehydrogenase activity
MKS87_00075	COG1686	Belongs to the peptidase S11 family
MKS87_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MKS87_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MKS87_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKS87_00100	COG1428	Deoxynucleoside kinase
MKS87_00105	COG1428	Deoxynucleoside kinase
MKS87_00110	COG1388	LysM domain
MKS87_00110	COG3858	chitin binding
MKS87_00115	COG1335	isochorismatase
MKS87_00120	COG0590	tRNA wobble adenosine to inosine editing
MKS87_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKS87_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKS87_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKS87_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MKS87_00190	COG3853	Toxic anion resistance protein (TelA)
MKS87_00195	COG1982	Orn Lys Arg decarboxylase major
MKS87_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKS87_00205	COG3870	Protein conserved in bacteria
MKS87_00210	COG1728	Protein conserved in bacteria
MKS87_00215	COG0470	DNA polymerase III
MKS87_00220	COG1774	PSP1 C-terminal conserved region
MKS87_00225	COG4467	Involved in initiation control of chromosome replication
MKS87_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MKS87_00235	COG2827	Endonuclease containing a URI domain
MKS87_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKS87_00245	COG2002	toxin-antitoxin pair type II binding
MKS87_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKS87_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKS87_00255	COG0084	hydrolase, TatD family'
MKS87_00260	COG3584	3D domain protein
MKS87_00260	COG3583	domain protein
MKS87_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKS87_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MKS87_00280	COG4466	Protein conserved in bacteria
MKS87_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKS87_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKS87_00300	COG0251	oxidation-reduction process
MKS87_00305	COG2088	sporulation resulting in formation of a cellular spore
MKS87_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKS87_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKS87_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MKS87_00325	COG0193	aminoacyl-tRNA hydrolase activity
MKS87_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKS87_00340	COG2002	toxin-antitoxin pair type II binding
MKS87_00345	COG2244	polysaccharide biosynthetic process
MKS87_00350	COG3956	TIGRFAM MazG family protein
MKS87_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MKS87_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MKS87_00375	COG1098	S1 RNA binding domain
MKS87_00390	COG2208	phosphoserine phosphatase activity
MKS87_00395	COG2304	oxidoreductase activity
MKS87_00400	COG0515	serine threonine protein kinase
MKS87_00405	COG0037	tRNA processing
MKS87_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MKS87_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKS87_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MKS87_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKS87_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MKS87_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MKS87_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKS87_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
MKS87_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MKS87_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKS87_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKS87_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKS87_00470	COG1396	sequence-specific DNA binding
MKS87_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKS87_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MKS87_00560	COG4463	regulation of RNA biosynthetic process
MKS87_00565	COG3880	PFAM UvrB UvrC protein
MKS87_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MKS87_00575	COG0542	response to heat
MKS87_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKS87_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MKS87_00590	COG4956	integral membrane protein (PIN domain superfamily)
MKS87_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MKS87_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MKS87_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKS87_00610	COG1045	serine acetyltransferase
MKS87_00615	COG0215	cysteine-tRNA ligase activity
MKS87_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKS87_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKS87_00630	COG3688	RNA-binding protein containing a PIN domain
MKS87_00635	COG1595	DNA-templated transcription, initiation
MKS87_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MKS87_00650	COG0250	Participates in transcription elongation, termination and antitermination
MKS87_00660	COG0081	regulation of translation
MKS87_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKS87_00675	COG2813	Specifically methylates the guanine in position
MKS87_00680	COG0085	RNA polymerase activity
MKS87_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKS87_00690	COG1358	cellular component organization or biogenesis
MKS87_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKS87_00700	COG0049	tRNA binding
MKS87_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKS87_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKS87_00715	COG0596	Alpha beta hydrolase
MKS87_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKS87_00730	COG0088	Forms part of the polypeptide exit tunnel
MKS87_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKS87_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKS87_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKS87_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKS87_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKS87_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKS87_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKS87_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKS87_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKS87_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKS87_00820	COG0200	Binds to the 23S rRNA
MKS87_00825	COG0201	protein transport
MKS87_00830	COG0563	adenylate kinase activity
MKS87_00835	COG0024	Methionine aminopeptidase
MKS87_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
MKS87_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MKS87_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKS87_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKS87_00865	COG0202	RNA polymerase activity
MKS87_00870	COG0203	ribosomal protein L17
MKS87_00875	COG1122	ATPase activity
MKS87_00880	COG1122	ATPase activity
MKS87_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKS87_00890	COG0101	tRNA pseudouridine synthase activity
MKS87_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKS87_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MKS87_00905	COG2226	methyltransferase
MKS87_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
MKS87_00920	COG0489	protein tyrosine kinase activity
MKS87_00930	COG2194	sulfuric ester hydrolase activity
MKS87_00935	COG0726	polysaccharide deacetylase
MKS87_01095	COG0659	secondary active sulfate transmembrane transporter activity
MKS87_01100	COG0385	Bile acid
MKS87_01105	COG2819	hydrolase of the alpha beta superfamily
MKS87_01110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_01115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_01120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKS87_01125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKS87_01125	COG2207	Transcriptional regulator
MKS87_01130	COG3876	Protein conserved in bacteria
MKS87_01135	COG1472	Belongs to the glycosyl hydrolase 3 family
MKS87_01140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MKS87_01145	COG1263	PTS System
MKS87_01145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_01150	COG1737	Transcriptional regulator
MKS87_01155	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKS87_01160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_01165	COG1683	Conserved Protein
MKS87_01195	COG1595	DNA-templated transcription, initiation
MKS87_01200	COG5662	AntiSigma factor
MKS87_01205	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKS87_01210	COG4856	YbbR-like protein
MKS87_01215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKS87_01220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MKS87_01230	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKS87_01235	COG2169	Transcriptional regulator
MKS87_01240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKS87_01245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MKS87_01250	COG3002	Belongs to the UPF0753 family
MKS87_01255	COG0288	reversible hydration of carbon dioxide
MKS87_01265	COG5609	conserved protein (DUF2294)
MKS87_01270	COG0640	Transcriptional regulator
MKS87_01275	COG2814	Major facilitator Superfamily
MKS87_01290	COG0596	Alpha beta hydrolase
MKS87_01295	COG0745	RESPONSE REGULATOR receiver
MKS87_01300	COG0642	Histidine kinase
MKS87_01310	COG0515	serine threonine protein kinase
MKS87_01325	COG1113	amino acid transport
MKS87_01340	COG2602	Beta-lactamase
MKS87_01345	COG2124	cytochrome p450
MKS87_01355	COG0531	amino acid
MKS87_01360	COG0584	glycerophosphoryl diester phosphodiesterase
MKS87_01365	COG2271	Major facilitator Superfamily
MKS87_01375	COG0456	acetyltransferase
MKS87_01375	COG1846	Transcriptional regulator
MKS87_01380	COG2271	Major facilitator Superfamily
MKS87_01390	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_01395	COG0697	spore germination
MKS87_01400	COG1917	Cupin 2, conserved barrel domain protein
MKS87_01400	COG2207	Transcriptional regulator
MKS87_01405	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKS87_01410	COG3591	Belongs to the peptidase S1B family
MKS87_01420	COG0596	Alpha beta hydrolase
MKS87_01425	COG1183	phosphatidylcholine synthase activity
MKS87_01430	COG0586	Pfam SNARE associated Golgi protein
MKS87_01435	COG0688	phosphatidylethanolamine metabolic process
MKS87_01450	COG1054	Belongs to the UPF0176 family
MKS87_01455	COG1301	dicarboxylic acid transport
MKS87_01460	COG1263	PTS System
MKS87_01460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_01460	COG2190	(PTS) system
MKS87_01465	COG0363	glucosamine-6-phosphate deaminase activity
MKS87_01470	COG2188	Transcriptional regulator
MKS87_01480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MKS87_01485	COG0833	amino acid
MKS87_01490	COG2040	homocysteine
MKS87_01495	COG1115	amino acid carrier protein
MKS87_01500	COG2066	Belongs to the glutaminase family
MKS87_01505	COG4191	Histidine kinase
MKS87_01510	COG0784	Response regulator, receiver
MKS87_01515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKS87_01520	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_01525	COG2271	Major facilitator Superfamily
MKS87_01530	COG4948	Mandelate Racemase Muconate Lactonizing
MKS87_01535	COG2186	Transcriptional regulator
MKS87_01540	COG2721	sulfolactate sulfo-lyase activity
MKS87_01545	COG3173	Aminoglycoside phosphotransferase
MKS87_01555	COG0697	spore germination
MKS87_01560	COG0745	RESPONSE REGULATOR receiver
MKS87_01565	COG2205	protein histidine kinase activity
MKS87_01570	COG1131	(ABC) transporter
MKS87_01590	COG3773	Cell wall hydrolase
MKS87_01595	COG2304	oxidoreductase activity
MKS87_01605	COG3540	Alkaline phosphatase
MKS87_01610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKS87_01615	COG0805	protein transport
MKS87_01620	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKS87_01625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKS87_01630	COG0477	Major facilitator Superfamily
MKS87_01635	COG1309	transcriptional regulator
MKS87_01640	COG0252	asparaginase activity
MKS87_01645	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKS87_01650	COG1714	RDD family
MKS87_01655	COG1405	negative regulation of cell septum assembly
MKS87_01655	COG3012	SEC-C Motif Domain Protein
MKS87_01660	COG3290	protein histidine kinase activity
MKS87_01665	COG3279	Response regulator of the LytR AlgR family
MKS87_01670	COG4555	ABC transporter
MKS87_01675	COG1668	transmembrane transport
MKS87_01680	COG0667	Aldo Keto reductase
MKS87_01695	COG1595	DNA-templated transcription, initiation
MKS87_01700	COG1595	DNA-templated transcription, initiation
MKS87_01705	COG1876	peptidase activity
MKS87_01710	COG0457	Tetratricopeptide repeat
MKS87_01715	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_01720	COG0366	Alpha amylase catalytic
MKS87_01725	COG0803	Belongs to the bacterial solute-binding protein 9 family
MKS87_01730	COG1121	(ABC) transporter
MKS87_01735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKS87_01740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKS87_01745	COG2310	stress, protein
MKS87_01750	COG2310	stress, protein
MKS87_01755	COG2310	stress, protein
MKS87_01760	COG0861	Integral membrane protein TerC family
MKS87_01770	COG3853	Toxic anion resistance protein (TelA)
MKS87_01775	COG0477	Major facilitator Superfamily
MKS87_01780	COG2814	Major facilitator Superfamily
MKS87_01785	COG0640	Transcriptional regulator
MKS87_01790	COG0517	IMP dehydrogenase activity
MKS87_01790	COG4175	Glycine betaine
MKS87_01795	COG4176	ABC-type proline glycine betaine transport system permease component
MKS87_01800	COG2113	Glycine betaine
MKS87_01805	COG1473	amidohydrolase
MKS87_01810	COG1288	antiporter activity
MKS87_01820	COG0366	Alpha amylase catalytic
MKS87_01825	COG0039	L-malate dehydrogenase activity
MKS87_01830	COG1620	l-lactate permease
MKS87_01835	COG2814	Major facilitator Superfamily
MKS87_01840	COG1846	Transcriptional regulator
MKS87_01845	COG1280	lysine exporter protein (LysE YggA)
MKS87_01850	COG3403	YqcI/YcgG family
MKS87_01855	COG1113	amino acid transport
MKS87_01860	COG3665	Urea carboxylase-associated protein
MKS87_01865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MKS87_01870	COG1660	Displays ATPase and GTPase activities
MKS87_01875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKS87_01880	COG2226	methyltransferase
MKS87_01885	COG0583	DNA-binding transcription factor activity
MKS87_01890	COG3458	cephalosporin-C deacetylase activity
MKS87_01895	COG3541	Predicted nucleotidyltransferase
MKS87_01900	COG0506	proline dehydrogenase activity
MKS87_01905	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_01910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKS87_01915	COG2508	Transcriptional regulator
MKS87_01920	COG3689	TIGRFAM TIGR03943 family protein
MKS87_01925	COG0701	Predicted permease
MKS87_01930	COG2267	carboxylic ester hydrolase activity
MKS87_01935	COG0492	ferredoxin-NADP+ reductase activity
MKS87_01940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MKS87_01940	COG1587	Uroporphyrinogen-III synthase
MKS87_01945	COG2146	nitrite reductase [NAD(P)H] activity
MKS87_01950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKS87_01955	COG0243	molybdopterin cofactor binding
MKS87_01960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKS87_01965	COG2223	nitrite transmembrane transporter activity
MKS87_01970	COG1469	GTP cyclohydrolase I activity
MKS87_01975	COG1376	ErfK ybiS ycfS ynhG family protein
MKS87_01990	COG0523	cobalamin synthesis protein
MKS87_01995	COG0765	amino acid transport
MKS87_02000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKS87_02010	COG1714	RDD family
MKS87_02020	COG2723	6-phospho-beta-galactosidase activity
MKS87_02030	COG3209	COG3209 Rhs family protein
MKS87_02035	COG0840	transmembrane signaling receptor activity
MKS87_02035	COG3290	protein histidine kinase activity
MKS87_02040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MKS87_02045	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MKS87_02050	COG1733	regulation of RNA biosynthetic process
MKS87_02055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_02075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_02080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_02085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MKS87_02090	COG2814	Major facilitator Superfamily
MKS87_02100	COG0697	spore germination
MKS87_02105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKS87_02115	COG2364	Membrane
MKS87_02120	COG1126	abc transporter atp-binding protein
MKS87_02125	COG0765	amino acid transport
MKS87_02130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKS87_02135	COG0583	DNA-binding transcription factor activity
MKS87_02140	COG0163	prenyltransferase activity
MKS87_02145	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MKS87_02160	COG0596	Alpha beta hydrolase
MKS87_02165	COG3104	oligopeptide transport
MKS87_02170	COG5434	Belongs to the glycosyl hydrolase 28 family
MKS87_02180	COG0697	spore germination
MKS87_02190	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MKS87_02195	COG1136	(ABC) transporter
MKS87_02200	COG0577	efflux transmembrane transporter activity
MKS87_02205	COG0745	RESPONSE REGULATOR receiver
MKS87_02210	COG3850	Histidine kinase
MKS87_02210	COG5002	protein histidine kinase activity
MKS87_02215	COG0457	Tetratricopeptide repeat
MKS87_02235	COG0527	aspartate kinase activity
MKS87_02240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_02245	COG4605	iron ion homeostasis
MKS87_02250	COG4604	ABC transporter, ATP-binding protein
MKS87_02255	COG4607	ABC-type enterochelin transport system periplasmic component
MKS87_02260	COG2814	Major facilitator Superfamily
MKS87_02265	COG1309	transcriptional regulator
MKS87_02270	COG0778	Nitroreductase
MKS87_02275	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MKS87_02280	COG0640	Transcriptional regulator
MKS87_02285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKS87_02290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKS87_02295	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_02300	COG4975	Glucose uptake
MKS87_02305	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_02310	COG4549	nuclear export factor GLE1
MKS87_02315	COG1276	copper resistance
MKS87_02315	COG2372	response to copper ion
MKS87_02320	COG1349	DNA-binding transcription factor activity
MKS87_02330	COG2213	PTS system mannitol-specific
MKS87_02335	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_02340	COG0246	Mannitol dehydrogenase
MKS87_02345	COG0473	3-isopropylmalate dehydrogenase activity
MKS87_02350	COG0681	Belongs to the peptidase S26 family
MKS87_02355	COG0412	Dienelactone hydrolase
MKS87_02360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MKS87_02370	COG0561	phosphatase activity
MKS87_02375	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MKS87_02380	COG1914	H( )-stimulated, divalent metal cation uptake system
MKS87_02385	COG4336	lyase activity
MKS87_02390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MKS87_02395	COG1984	allophanate hydrolase subunit 2
MKS87_02400	COG1414	Transcriptional regulator
MKS87_02405	COG2755	lipolytic protein G-D-S-L family
MKS87_02415	COG2329	Antibiotic biosynthesis monooxygenase
MKS87_02420	COG0768	penicillin binding
MKS87_02425	COG4989	oxidoreductase activity
MKS87_02430	COG3711	transcriptional antiterminator
MKS87_02435	COG0318	PFAM AMP-dependent synthetase and ligase
MKS87_02440	COG2226	methyltransferase
MKS87_02445	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_02450	COG1917	Cupin 2, conserved barrel domain protein
MKS87_02455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_02460	COG3871	stress protein (general stress protein 26)
MKS87_02470	COG2814	Major facilitator Superfamily
MKS87_02475	COG1522	sequence-specific DNA binding
MKS87_02480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKS87_02480	COG0551	DNA topoisomerase type I activity
MKS87_02485	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MKS87_02490	COG3706	GGDEF domain
MKS87_02495	COG5298	Protein conserved in bacteria
MKS87_02500	COG1215	transferase activity, transferring glycosyl groups
MKS87_02510	COG0531	amino acid
MKS87_02515	COG0494	nUDIX hydrolase
MKS87_02520	COG0028	Belongs to the TPP enzyme family
MKS87_02545	COG1914	H( )-stimulated, divalent metal cation uptake system
MKS87_02550	COG2261	transglycosylase associated protein
MKS87_02555	COG4876	unkown
MKS87_02560	COG2217	Heavy metal translocating P-type atpase
MKS87_02565	COG3729	General stress protein
MKS87_02570	COG0662	Cupin 2, conserved barrel domain protein
MKS87_02575	COG2329	Antibiotic biosynthesis monooxygenase
MKS87_02580	COG3546	catalase activity
MKS87_02585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MKS87_02590	COG3290	protein histidine kinase activity
MKS87_02595	COG4565	transcriptional regulatory protein
MKS87_02600	COG1301	dicarboxylic acid transport
MKS87_02605	COG0628	permease
MKS87_02615	COG1131	(ABC) transporter
MKS87_02620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MKS87_02630	COG1960	acyl-CoA dehydrogenase activity
MKS87_02645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKS87_02650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_02655	COG1181	Belongs to the D-alanine--D-alanine ligase family
MKS87_02660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MKS87_02665	COG0513	Belongs to the DEAD box helicase family
MKS87_02670	COG3402	PFAM membrane-flanked domain
MKS87_02675	COG3428	Bacterial PH domain
MKS87_02680	COG0705	Rhomboid family
MKS87_02685	COG0736	holo-[acyl-carrier-protein] synthase activity
MKS87_02690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MKS87_02695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKS87_02700	COG0864	Transcriptional regulator
MKS87_02705	COG2337	Toxic component of a toxin-antitoxin (TA) module
MKS87_02710	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_02715	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_02720	COG2172	sigma factor antagonist activity
MKS87_02725	COG2208	phosphoserine phosphatase activity
MKS87_02730	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_02735	COG2172	sigma factor antagonist activity
MKS87_02740	COG1191	sigma factor activity
MKS87_02745	COG2208	phosphoserine phosphatase activity
MKS87_02765	COG1673	EVE domain
MKS87_02770	COG1846	Transcriptional regulator
MKS87_02775	COG2183	response to ionizing radiation
MKS87_02785	COG3091	SprT-like family
MKS87_02825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_02835	COG5444	nuclease activity
MKS87_02840	COG1476	TRANSCRIPTIONal
MKS87_02850	COG3239	Fatty acid desaturase
MKS87_02855	COG1278	Cold shock
MKS87_02865	COG0697	spore germination
MKS87_02870	COG1917	Cupin 2, conserved barrel domain protein
MKS87_02870	COG2207	Transcriptional regulator
MKS87_02875	COG0697	spore germination
MKS87_02880	COG3708	Transcriptional regulator
MKS87_02880	COG2207	Transcriptional regulator
MKS87_02885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKS87_02890	COG0477	Major facilitator Superfamily
MKS87_02900	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MKS87_02910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_02915	COG1309	transcriptional regulator
MKS87_02920	COG0697	spore germination
MKS87_02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKS87_02930	COG2030	dehydratase
MKS87_02935	COG3545	Serine hydrolase
MKS87_02940	COG1733	regulation of RNA biosynthetic process
MKS87_02945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKS87_02950	COG1733	regulation of RNA biosynthetic process
MKS87_02955	COG2249	NAD(P)H dehydrogenase (quinone) activity
MKS87_02960	COG2814	Major facilitator Superfamily
MKS87_02965	COG1309	transcriptional regulator
MKS87_02970	COG0640	Transcriptional regulator
MKS87_02975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKS87_02985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_02990	COG0697	spore germination
MKS87_02995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKS87_03000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKS87_03005	COG0640	Transcriptional regulator
MKS87_03010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKS87_03025	COG4585	Histidine kinase
MKS87_03030	COG2197	response regulator
MKS87_03035	COG2409	Drug exporters of the RND superfamily
MKS87_03040	COG0596	Alpha beta hydrolase
MKS87_03045	COG1811	Na channel or pump
MKS87_03050	COG0789	Transcriptional regulator
MKS87_03050	COG4978	Transcriptional regulator
MKS87_03055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKS87_03060	COG0778	Nitroreductase
MKS87_03065	COG0346	lactoylglutathione lyase activity
MKS87_03070	COG2259	Doxx family
MKS87_03075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_03095	COG2323	membrane
MKS87_03100	COG2323	membrane
MKS87_03105	COG0071	Belongs to the small heat shock protein (HSP20) family
MKS87_03120	COG1309	transcriptional regulator
MKS87_03130	COG0456	acetyltransferase
MKS87_03140	COG0673	inositol 2-dehydrogenase activity
MKS87_03145	COG1609	Transcriptional regulator
MKS87_03150	COG2814	Major facilitator Superfamily
MKS87_03155	COG1082	Xylose isomerase domain protein TIM barrel
MKS87_03160	COG0488	(ABC) transporter
MKS87_03165	COG1113	amino acid transport
MKS87_03170	COG2318	DinB family
MKS87_03175	COG1846	Transcriptional regulator
MKS87_03180	COG2409	Drug exporters of the RND superfamily
MKS87_03180	COG1033	growth of symbiont in host cell
MKS87_03185	COG0778	Nitroreductase
MKS87_03190	COG1846	Transcriptional regulator
MKS87_03195	COG2814	Major facilitator Superfamily
MKS87_03200	COG0730	response to heat
MKS87_03205	COG1802	Transcriptional regulator
MKS87_03210	COG1388	LysM domain
MKS87_03210	COG3858	chitin binding
MKS87_03215	COG1819	glycosyl
MKS87_03225	COG1785	Belongs to the alkaline phosphatase family
MKS87_03230	COG5646	InterPro IPR014922
MKS87_03240	COG0454	-acetyltransferase
MKS87_03245	COG1078	dGTPase activity
MKS87_03250	COG1388	LysM domain
MKS87_03255	COG2814	Major facilitator Superfamily
MKS87_03260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKS87_03265	COG1447	Phosphotransferase system cellobiose-specific component IIA
MKS87_03270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKS87_03275	COG2723	6-phospho-beta-galactosidase activity
MKS87_03280	COG2188	Transcriptional regulator
MKS87_03285	COG1940	carbohydrate kinase activity
MKS87_03290	COG1482	cell wall glycoprotein biosynthetic process
MKS87_03295	COG4124	Belongs to the glycosyl hydrolase 26 family
MKS87_03340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MKS87_03345	COG0802	atpase or kinase
MKS87_03350	COG1214	PFAM Peptidase M22, glycoprotease
MKS87_03355	COG0456	acetyltransferase
MKS87_03360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKS87_03365	COG0488	(ABC) transporter
MKS87_03370	COG0315	cyclic pyranopterin monophosphate synthase activity
MKS87_03375	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKS87_03380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKS87_03385	COG0805	protein transport
MKS87_03395	COG1266	CAAX protease self-immunity
MKS87_03405	COG0459	protein refolding
MKS87_03415	COG1073	alpha beta
MKS87_03420	COG0457	Tetratricopeptide repeat
MKS87_03425	COG1063	alcohol dehydrogenase
MKS87_03430	COG2211	Major facilitator Superfamily
MKS87_03435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKS87_03440	COG1842	Phage shock protein A
MKS87_03445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKS87_03450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MKS87_03455	COG4260	virion core protein, lumpy skin disease virus
MKS87_03465	COG2814	Major facilitator Superfamily
MKS87_03470	COG1063	alcohol dehydrogenase
MKS87_03475	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MKS87_03480	COG0823	Involved in the tonB-independent uptake of proteins
MKS87_03495	COG2267	carboxylic ester hydrolase activity
MKS87_03505	COG2132	Multicopper oxidase
MKS87_03510	COG1113	amino acid transport
MKS87_03520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKS87_03525	COG0714	Associated with various cellular activities
MKS87_03530	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MKS87_03535	COG1305	Transglutaminase-like
MKS87_03540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MKS87_03540	COG0519	Catalyzes the synthesis of GMP from XMP
MKS87_03555	COG2252	PERMEase
MKS87_03560	COG3064	Membrane
MKS87_03570	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MKS87_03580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKS87_03585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKS87_03590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKS87_03595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MKS87_03600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKS87_03605	COG0047	phosphoribosylformylglycinamidine synthase activity
MKS87_03610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKS87_03615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKS87_03620	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MKS87_03625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKS87_03630	COG0138	bifunctional purine biosynthesis protein purh
MKS87_03635	COG0151	Belongs to the GarS family
MKS87_03640	COG1522	sequence-specific DNA binding
MKS87_03645	COG0531	amino acid
MKS87_03655	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKS87_03660	COG1470	cell adhesion involved in biofilm formation
MKS87_03665	COG4496	protein, YerC YecD
MKS87_03670	COG0069	glutamate synthase activity
MKS87_03675	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MKS87_03680	COG0210	DNA helicase
MKS87_03685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKS87_03690	COG4851	CamS sex pheromone cAM373 precursor
MKS87_03695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKS87_03700	COG1285	pathogenesis
MKS87_03705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKS87_03710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKS87_03715	COG0154	amidase activity
MKS87_03720	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKS87_03730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKS87_03735	COG1597	lipid kinase activity
MKS87_03740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKS87_03755	COG0210	DNA helicase
MKS87_03795	COG5444	nuclease activity
MKS87_03805	COG3586	endonuclease activity
MKS87_03815	COG0457	Tetratricopeptide repeat
MKS87_03825	COG0217	transcriptional regulatory protein
MKS87_03835	COG1309	transcriptional regulator
MKS87_03840	COG3631	Ketosteroid isomerase-related protein
MKS87_03860	COG3546	catalase activity
MKS87_03865	COG0454	-acetyltransferase
MKS87_03875	COG5578	integral membrane protein
MKS87_03880	COG2972	Histidine kinase
MKS87_03885	COG4753	response regulator
MKS87_03885	COG2207	Transcriptional regulator
MKS87_03890	COG1653	transport
MKS87_03895	COG1175	transmembrane transport
MKS87_03900	COG0395	ABC-type sugar transport system, permease component
MKS87_03905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MKS87_03910	COG2207	Transcriptional regulator
MKS87_03915	COG2755	lipolytic protein G-D-S-L family
MKS87_03925	COG5578	integral membrane protein
MKS87_03930	COG3401	FG-GAP repeat protein
MKS87_03935	COG3401	FG-GAP repeat protein
MKS87_03940	COG2755	lipolytic protein G-D-S-L family
MKS87_03945	COG1874	Beta-galactosidase
MKS87_03955	COG1653	transport
MKS87_03960	COG4209	transmembrane transport
MKS87_03965	COG0395	ABC-type sugar transport system, permease component
MKS87_03970	COG1486	melibiose metabolic process
MKS87_03975	COG2323	membrane
MKS87_03980	COG2329	Antibiotic biosynthesis monooxygenase
MKS87_03985	COG0346	lactoylglutathione lyase activity
MKS87_04000	COG5583	Uncharacterized small protein (DUF2292)
MKS87_04005	COG0670	Belongs to the BI1 family
MKS87_04010	COG0697	spore germination
MKS87_04015	COG1846	Transcriptional regulator
MKS87_04020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MKS87_04030	COG2124	cytochrome p450
MKS87_04030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKS87_04035	COG1368	sulfuric ester hydrolase activity
MKS87_04040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MKS87_04045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKS87_04050	COG1442	glycosyl transferase family 8
MKS87_04055	COG1216	Glycosyl transferase, family 2
MKS87_04060	COG1442	glycosyl transferase family 8
MKS87_04065	COG2223	nitrite transmembrane transporter activity
MKS87_04070	COG1011	Hydrolase
MKS87_04075	COG0531	amino acid
MKS87_04080	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_04085	COG0840	transmembrane signaling receptor activity
MKS87_04090	COG0488	(ABC) transporter
MKS87_04100	COG0789	Transcriptional regulator
MKS87_04105	COG2814	Major facilitator Superfamily
MKS87_04115	COG0488	(ABC) transporter
MKS87_04120	COG0513	Belongs to the DEAD box helicase family
MKS87_04125	COG0456	acetyltransferase
MKS87_04130	COG2130	NADP-dependent
MKS87_04135	COG2211	Major facilitator Superfamily
MKS87_04140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MKS87_04145	COG1120	ATPase activity
MKS87_04150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_04155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_04160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MKS87_04175	COG3866	Pectate lyase
MKS87_04180	COG0471	metal ion transport
MKS87_04185	COG3290	protein histidine kinase activity
MKS87_04190	COG4565	transcriptional regulatory protein
MKS87_04195	COG3181	Tripartite tricarboxylate transporter family receptor
MKS87_04200	COG2851	Citrate transporter
MKS87_04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_04210	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MKS87_04215	COG1254	Belongs to the acylphosphatase family
MKS87_04220	COG2258	MOSC domain
MKS87_04240	COG0024	Methionine aminopeptidase
MKS87_04245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_04245	COG1263	PTS System
MKS87_04250	COG1368	sulfuric ester hydrolase activity
MKS87_04265	COG1115	amino acid carrier protein
MKS87_04270	COG0531	amino acid
MKS87_04285	COG0697	spore germination
MKS87_04290	COG1263	PTS System
MKS87_04290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_04295	COG0366	Alpha amylase catalytic
MKS87_04300	COG2188	Transcriptional regulator
MKS87_04305	COG0778	Nitroreductase
MKS87_04310	COG0737	Belongs to the 5'-nucleotidase family
MKS87_04315	COG0693	protein deglycase activity
MKS87_04320	COG2814	Major facilitator Superfamily
MKS87_04325	COG4840	Belongs to the UPF0435 family
MKS87_04330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKS87_04335	COG4980	gas vesicle protein
MKS87_04340	COG1295	ribonuclease BN
MKS87_04345	COG0477	Major facilitator Superfamily
MKS87_04350	COG0387	Pfam Sodium calcium exchanger
MKS87_04360	COG0668	transmembrane transport
MKS87_04365	COG0535	radical SAM domain protein
MKS87_04375	COG0726	polysaccharide deacetylase
MKS87_04380	COG2084	Dehydrogenase
MKS87_04385	COG0598	Magnesium transport protein CorA
MKS87_04390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKS87_04395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKS87_04400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKS87_04415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MKS87_04420	COG0022	dehydrogenase e1 component
MKS87_04425	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKS87_04430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKS87_04435	COG3284	Transcriptional regulator
MKS87_04445	COG1742	UPF0060 membrane protein
MKS87_04465	COG4842	Belongs to the WXG100 family
MKS87_04470	COG1486	melibiose metabolic process
MKS87_04475	COG1737	Transcriptional regulator
MKS87_04480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_04480	COG1263	PTS System
MKS87_04485	COG5434	Belongs to the glycosyl hydrolase 28 family
MKS87_04490	COG1132	(ABC) transporter
MKS87_04495	COG1132	(ABC) transporter
MKS87_04500	COG2259	Doxx family
MKS87_04505	COG2514	catechol 2,3-dioxygenase activity
MKS87_04510	COG4585	Histidine kinase
MKS87_04515	COG2197	response regulator
MKS87_04520	COG1131	(ABC) transporter
MKS87_04525	COG0842	Transport permease protein
MKS87_04525	COG1511	domain protein
MKS87_04530	COG0842	Transport permease protein
MKS87_04535	COG1695	Transcriptional regulator
MKS87_04540	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKS87_04545	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MKS87_04550	COG2318	DinB family
MKS87_04555	COG2814	Major facilitator Superfamily
MKS87_04560	COG1846	Transcriptional regulator
MKS87_04565	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKS87_04565	COG0392	lysyltransferase activity
MKS87_04570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKS87_04575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_04580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_04585	COG0384	phenazine biosynthesis protein PhzF
MKS87_04590	COG0778	Nitroreductase
MKS87_04605	COG1090	epimerase
MKS87_04610	COG2137	regulation of response to DNA damage stimulus
MKS87_04620	COG2814	Major facilitator Superfamily
MKS87_04635	COG3103	Sh3 type 3 domain protein
MKS87_04640	COG5658	integral membrane protein
MKS87_04645	COG0596	Alpha beta hydrolase
MKS87_04650	COG0463	Glycosyl transferase, family 2
MKS87_04655	COG4485	Bacterial membrane protein, YfhO
MKS87_04660	COG1988	membrane-bound metal-dependent
MKS87_04665	COG1194	a g-specific adenine glycosylase
MKS87_04675	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_04690	COG3557	Belongs to the UPF0374 family
MKS87_04695	COG1132	(ABC) transporter
MKS87_04700	COG4129	membrane
MKS87_04705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MKS87_04710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MKS87_04715	COG0735	belongs to the Fur family
MKS87_04825	COG4326	sporulation control protein
MKS87_04835	COG5577	PFAM Coat F domain
MKS87_04840	COG3340	Belongs to the peptidase S51 family
MKS87_04845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MKS87_04850	COG0277	FAD linked oxidase domain protein
MKS87_04860	COG0753	catalase activity
MKS87_04865	COG1116	anion transmembrane transporter activity
MKS87_04870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MKS87_04875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MKS87_04880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKS87_04890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKS87_04900	COG1476	TRANSCRIPTIONal
MKS87_04910	COG3382	B3 4 domain protein
MKS87_04915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKS87_04925	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MKS87_04930	COG0789	Transcriptional regulator
MKS87_04935	COG1664	Polymer-forming cytoskeletal
MKS87_04940	COG1664	Polymer-forming cytoskeletal
MKS87_04945	COG2766	serine protein kinase
MKS87_04950	COG2718	Belongs to the UPF0229 family
MKS87_04955	COG1846	Transcriptional regulator
MKS87_04960	COG1566	PFAM secretion protein HlyD family protein
MKS87_04965	COG2814	Major facilitator Superfamily
MKS87_04970	COG0655	NAD(P)H dehydrogenase (quinone) activity
MKS87_04990	COG1725	Transcriptional regulator
MKS87_04995	COG1131	(ABC) transporter
MKS87_05000	COG1131	(ABC) transporter
MKS87_05005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MKS87_05010	COG1278	Cold shock
MKS87_05015	COG1464	Belongs to the NlpA lipoprotein family
MKS87_05020	COG3706	GGDEF domain
MKS87_05025	COG1823	symporter activity
MKS87_05045	COG5577	PFAM Coat F domain
MKS87_05050	COG4085	toxin activity
MKS87_05050	COG1525	nuclease
MKS87_05050	COG0737	Belongs to the 5'-nucleotidase family
MKS87_05055	COG3764	Sortase (surface protein transpeptidase)
MKS87_05060	COG0564	pseudouridine synthase activity
MKS87_05070	COG0517	IMP dehydrogenase activity
MKS87_05075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MKS87_05080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MKS87_05080	COG3153	acetyltransferase
MKS87_05085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MKS87_05090	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKS87_05095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MKS87_05100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKS87_05105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MKS87_05110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKS87_05115	COG4585	Histidine kinase
MKS87_05115	COG2203	Gaf domain
MKS87_05120	COG2197	response regulator
MKS87_05125	COG0431	NADPH-dependent FMN reductase
MKS87_05140	COG1388	LysM domain
MKS87_05140	COG0791	NLP P60 protein
MKS87_05145	COG1959	2 iron, 2 sulfur cluster binding
MKS87_05150	COG0668	transmembrane transport
MKS87_05155	COG2719	SpoVR family
MKS87_05160	COG1785	Belongs to the alkaline phosphatase family
MKS87_05165	COG1388	LysM domain
MKS87_05165	COG0791	NLP P60 protein
MKS87_05170	COG0583	DNA-binding transcription factor activity
MKS87_05175	COG0372	Belongs to the citrate synthase family
MKS87_05180	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_05185	COG0531	amino acid
MKS87_05190	COG0733	neurotransmitter:sodium symporter activity
MKS87_05195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MKS87_05200	COG0456	acetyltransferase
MKS87_05215	COG1595	DNA-templated transcription, initiation
MKS87_05220	COG0667	Aldo Keto reductase
MKS87_05225	COG0204	Acyl-transferase
MKS87_05230	COG1253	flavin adenine dinucleotide binding
MKS87_05235	COG0789	Transcriptional regulator
MKS87_05240	COG0436	Aminotransferase
MKS87_05245	COG1253	flavin adenine dinucleotide binding
MKS87_05250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKS87_05255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKS87_05260	COG0584	glycerophosphoryl diester phosphodiesterase
MKS87_05270	COG0668	transmembrane transport
MKS87_05275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MKS87_05280	COG0726	polysaccharide deacetylase
MKS87_05285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MKS87_05290	COG1757	Na H antiporter
MKS87_05295	COG0589	response to stress
MKS87_05305	COG1132	(ABC) transporter
MKS87_05310	COG1132	(ABC) transporter
MKS87_05315	COG0702	epimerase
MKS87_05335	COG0189	ligase activity
MKS87_05340	COG0189	ligase activity
MKS87_05345	COG4399	Belongs to the UPF0754 family
MKS87_05350	COG3679	Belongs to the UPF0342 family
MKS87_05355	COG4335	DNA alkylation repair
MKS87_05360	COG0561	phosphatase activity
MKS87_05365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MKS87_05370	COG0475	glutathione-regulated potassium exporter activity
MKS87_05375	COG0490	domain, Protein
MKS87_05385	COG1024	Enoyl-CoA hydratase
MKS87_05395	COG4152	abc transporter atp-binding protein
MKS87_05400	COG1668	transmembrane transport
MKS87_05405	COG0420	3'-5' exonuclease activity
MKS87_05410	COG4717	serine-type aminopeptidase activity
MKS87_05415	COG3481	metal-dependent phosphohydrolase, HD sub domain
MKS87_05425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MKS87_05455	COG1846	Transcriptional regulator
MKS87_05460	COG4980	gas vesicle protein
MKS87_05475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKS87_05480	COG0537	adenosine 5'-monophosphoramidase activity
MKS87_05485	COG1131	(ABC) transporter
MKS87_05490	COG4473	ABC transporter
MKS87_05500	COG1473	amidohydrolase
MKS87_05505	COG3069	C4-dicarboxylate transmembrane transporter activity
MKS87_05515	COG2329	Antibiotic biosynthesis monooxygenase
MKS87_05520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKS87_05525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MKS87_05530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MKS87_05535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKS87_05540	COG1309	transcriptional regulator
MKS87_05545	COG1511	domain protein
MKS87_05550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKS87_05555	COG4377	Putative membrane peptidase family (DUF2324)
MKS87_05565	COG1363	Peptidase, m42
MKS87_05570	COG4405	Protein conserved in bacteria
MKS87_05575	COG1301	dicarboxylic acid transport
MKS87_05585	COG1234	tRNA 3'-trailer cleavage
MKS87_05590	COG0095	Lipoate-protein ligase
MKS87_05595	COG0702	epimerase
MKS87_05600	COG0318	PFAM AMP-dependent synthetase and ligase
MKS87_05610	COG0501	Belongs to the peptidase M48B family
MKS87_05615	COG1404	Belongs to the peptidase S8 family
MKS87_05620	COG0456	acetyltransferase
MKS87_05625	COG0604	alcohol dehydrogenase
MKS87_05630	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MKS87_05635	COG0406	alpha-ribazole phosphatase activity
MKS87_05640	COG0183	Belongs to the thiolase family
MKS87_05645	COG0318	PFAM AMP-dependent synthetase and ligase
MKS87_05650	COG1268	BioY protein
MKS87_05655	COG0840	transmembrane signaling receptor activity
MKS87_05660	COG0723	plastoquinol--plastocyanin reductase activity
MKS87_05660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MKS87_05665	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_05675	COG4903	ComK protein
MKS87_05680	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_05690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKS87_05705	COG0398	Pfam SNARE associated Golgi protein
MKS87_05710	COG0681	Belongs to the peptidase S26 family
MKS87_05715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MKS87_05720	COG1846	Transcriptional regulator
MKS87_05725	COG0738	Major facilitator superfamily
MKS87_05730	COG0673	inositol 2-dehydrogenase activity
MKS87_05735	COG0561	phosphatase activity
MKS87_05740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MKS87_05745	COG1609	Transcriptional regulator
MKS87_05750	COG3180	Ammonia monooxygenase
MKS87_05755	COG2814	Major facilitator Superfamily
MKS87_05755	COG0477	Major facilitator Superfamily
MKS87_05760	COG4533	DNA binding
MKS87_05770	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MKS87_05775	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MKS87_05780	COG1074	ATP-dependent DNA helicase activity
MKS87_05785	COG0420	3'-5' exonuclease activity
MKS87_05790	COG0419	ATPase involved in DNA repair
MKS87_05795	COG1403	HNH endonuclease
MKS87_05835	COG5337	Spore coat protein CotH
MKS87_05840	COG0179	Fumarylacetoacetate (FAA) hydrolase
MKS87_05850	COG1404	Belongs to the peptidase S8 family
MKS87_05860	COG0367	asparagine synthase
MKS87_05865	COG2318	DinB family
MKS87_05870	COG1562	ergosterol biosynthetic process
MKS87_05875	COG0534	Mate efflux family protein
MKS87_05880	COG2207	Transcriptional regulator
MKS87_05880	COG1917	Cupin 2, conserved barrel domain protein
MKS87_05885	COG1609	Transcriptional regulator
MKS87_05890	COG0673	inositol 2-dehydrogenase activity
MKS87_05895	COG2318	DinB family
MKS87_05900	COG1279	arginine transmembrane transporter activity
MKS87_05910	COG1357	PFAM Pentapeptide repeats (8 copies)
MKS87_05915	COG2267	carboxylic ester hydrolase activity
MKS87_05920	COG0529	Catalyzes the synthesis of activated sulfate
MKS87_05925	COG2046	Belongs to the sulfate adenylyltransferase family
MKS87_05930	COG0175	sulfate reduction
MKS87_05935	COG2045	Belongs to the ComB family
MKS87_05940	COG1809	phosphosulfolactate synthase activity
MKS87_05945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKS87_05950	COG4948	Mandelate Racemase Muconate Lactonizing
MKS87_05955	COG2814	Major facilitator Superfamily
MKS87_05960	COG0454	-acetyltransferase
MKS87_05965	COG2153	protein acetylation
MKS87_05970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MKS87_05970	COG0646	methionine synthase
MKS87_05975	COG1666	GTP binding
MKS87_05980	COG2996	Protein conserved in bacteria
MKS87_06000	COG1695	Transcriptional regulator
MKS87_06015	COG3227	Zinc metalloprotease (Elastase)
MKS87_06020	COG1307	EDD domain protein, DegV family
MKS87_06025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKS87_06045	COG0561	phosphatase activity
MKS87_06050	COG1073	alpha beta
MKS87_06055	COG2151	metal-sulfur cluster biosynthetic enzyme
MKS87_06065	COG0277	FAD linked oxidase domain protein
MKS87_06070	COG2271	Major facilitator Superfamily
MKS87_06075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKS87_06080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKS87_06090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MKS87_06095	COG0505	Belongs to the CarA family
MKS87_06100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MKS87_06105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKS87_06120	COG2267	carboxylic ester hydrolase activity
MKS87_06130	COG1744	ABC transporter substrate-binding protein PnrA-like
MKS87_06145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKS87_06150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MKS87_06155	COG5504	Zn-dependent protease
MKS87_06160	COG0444	Belongs to the ABC transporter superfamily
MKS87_06165	COG4608	Belongs to the ABC transporter superfamily
MKS87_06175	COG0601	transmembrane transport
MKS87_06180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKS87_06190	COG0180	Tryptophanyl-tRNA synthetase
MKS87_06195	COG4166	transmembrane transport
MKS87_06200	COG0601	transmembrane transport
MKS87_06205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKS87_06210	COG0444	Belongs to the ABC transporter superfamily
MKS87_06215	COG4608	Belongs to the ABC transporter superfamily
MKS87_06220	COG2814	Major facilitator Superfamily
MKS87_06225	COG0456	acetyltransferase
MKS87_06230	COG1393	Belongs to the ArsC family
MKS87_06235	COG0861	Integral membrane protein TerC family
MKS87_06245	COG4862	establishment of competence for transformation
MKS87_06255	COG4469	Competence protein
MKS87_06260	COG1164	Oligoendopeptidase f
MKS87_06270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MKS87_06275	COG2346	COG2346, Truncated hemoglobins
MKS87_06280	COG0741	lytic transglycosylase activity
MKS87_06285	COG4116	CYTH
MKS87_06295	COG2357	RelA SpoT domain protein
MKS87_06300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKS87_06305	COG0564	pseudouridine synthase activity
MKS87_06310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MKS87_06315	COG0475	glutathione-regulated potassium exporter activity
MKS87_06315	COG0569	domain protein
MKS87_06320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKS87_06325	COG0352	thiamine-phosphate diphosphorylase activity
MKS87_06330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MKS87_06335	COG2104	thiamine diphosphate biosynthetic process
MKS87_06340	COG2022	thiamine diphosphate biosynthetic process
MKS87_06345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MKS87_06350	COG0351	phosphomethylpyrimidine kinase
MKS87_06355	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MKS87_06410	COG0210	DNA helicase
MKS87_06420	COG2153	protein acetylation
MKS87_06425	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MKS87_06430	COG2382	esterase
MKS87_06435	COG0626	cystathionine gamma-synthase activity
MKS87_06440	COG0626	cystathionine gamma-synthase activity
MKS87_06445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_06450	COG5505	Protein of unknown function (DUF819)
MKS87_06480	COG5444	nuclease activity
MKS87_06500	COG0457	Tetratricopeptide repeat
MKS87_06505	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MKS87_06510	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_06520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_06520	COG3711	transcriptional antiterminator
MKS87_06525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_06525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKS87_06525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKS87_06530	COG1482	cell wall glycoprotein biosynthetic process
MKS87_06540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_06550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKS87_06565	COG0109	protoheme IX farnesyltransferase activity
MKS87_06575	COG0726	polysaccharide deacetylase
MKS87_06590	COG5504	Zn-dependent protease
MKS87_06595	COG2205	protein histidine kinase activity
MKS87_06605	COG3383	formate dehydrogenase (NAD+) activity
MKS87_06610	COG2427	Protein of unknown function (DUF1641)
MKS87_06620	COG1051	belongs to the nudix hydrolase family
MKS87_06630	COG2124	cytochrome p450
MKS87_06635	COG1819	glycosyl
MKS87_06645	COG1587	Uroporphyrinogen-III synthase
MKS87_06650	COG0390	transport system, permease component
MKS87_06655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MKS87_06660	COG0697	spore germination
MKS87_06665	COG4297	protein containing double-stranded beta helix domain
MKS87_06675	COG1252	NADH dehydrogenase
MKS87_06680	COG1904	glucuronate isomerase
MKS87_06685	COG2211	Major facilitator Superfamily
MKS87_06690	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MKS87_06695	COG1063	alcohol dehydrogenase
MKS87_06700	COG1312	Catalyzes the dehydration of D-mannonate
MKS87_06705	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_06710	COG2271	Major facilitator Superfamily
MKS87_06715	COG1609	Transcriptional regulator
MKS87_06720	COG0246	Mannitol dehydrogenase
MKS87_06725	COG2721	sulfolactate sulfo-lyase activity
MKS87_06730	COG0730	response to heat
MKS87_06735	COG2318	DinB family
MKS87_06740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKS87_06745	COG0457	Tetratricopeptide repeat
MKS87_06755	COG2350	Protein conserved in bacteria
MKS87_06760	COG1388	LysM domain
MKS87_06760	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKS87_06760	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_06770	COG4195	phage-related replication protein
MKS87_06775	COG3546	catalase activity
MKS87_06780	COG2856	Zn peptidase
MKS87_06785	COG1396	sequence-specific DNA binding
MKS87_06795	COG1522	sequence-specific DNA binding
MKS87_06800	COG1484	DNA-dependent DNA replication
MKS87_06820	COG1595	DNA-templated transcription, initiation
MKS87_06825	COG3728	DNA packaging
MKS87_06825	COG5484	DNA packaging
MKS87_06830	COG1783	phage Terminase large subunit
MKS87_06835	COG5518	Phage portal protein
MKS87_06840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MKS87_06845	COG4653	Phage capsid family
MKS87_06895	COG5412	phage tail tape measure protein
MKS87_06895	COG3953	SLT domain
MKS87_06895	COG5412	phage tail tape measure protein
MKS87_06895	COG3953	SLT domain
MKS87_06900	COG1652	LysM domain
MKS87_06905	COG4193	domain, Protein
MKS87_06915	COG3628	GPW Gp25 family protein
MKS87_06920	COG3299	homolog of phage Mu protein gp47
MKS87_06925	COG3778	Protein conserved in bacteria
MKS87_06965	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKS87_06965	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_06985	COG0306	phosphate transporter
MKS87_06990	COG1392	Phosphate transport regulator
MKS87_06995	COG0531	amino acid
MKS87_07000	COG0346	lactoylglutathione lyase activity
MKS87_07010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKS87_07015	COG0463	Glycosyl transferase, family 2
MKS87_07025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKS87_07030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKS87_07035	COG2362	D-Aminopeptidase
MKS87_07040	COG0601	transmembrane transport
MKS87_07045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKS87_07050	COG0444	Belongs to the ABC transporter superfamily
MKS87_07055	COG4166	transmembrane transport
MKS87_07060	COG1619	proteins homologs of microcin C7 resistance protein MccF
MKS87_07065	COG4948	Mandelate Racemase Muconate Lactonizing
MKS87_07070	COG0791	NLP P60 protein
MKS87_07075	COG4608	Belongs to the ABC transporter superfamily
MKS87_07080	COG2706	6-phosphogluconolactonase activity
MKS87_07085	COG1834	amidinotransferase
MKS87_07090	COG1607	acyl-coa hydrolase
MKS87_07095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKS87_07095	COG1017	nitric oxide dioxygenase activity
MKS87_07105	COG2323	membrane
MKS87_07110	COG2318	DinB family
MKS87_07115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_07120	COG2076	Multidrug Resistance protein
MKS87_07125	COG2076	Multidrug Resistance protein
MKS87_07130	COG0788	formyltetrahydrofolate deformylase activity
MKS87_07135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKS87_07140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKS87_07145	COG1764	response to oxidative stress
MKS87_07150	COG1846	Transcriptional regulator
MKS87_07155	COG1764	response to oxidative stress
MKS87_07165	COG0590	tRNA wobble adenosine to inosine editing
MKS87_07170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKS87_07175	COG1404	Belongs to the peptidase S8 family
MKS87_07180	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_07185	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKS87_07190	COG1122	ATPase activity
MKS87_07195	COG4721	ABC-type cobalt transport system, permease component
MKS87_07205	COG0745	RESPONSE REGULATOR receiver
MKS87_07210	COG3850	Histidine kinase
MKS87_07210	COG5002	protein histidine kinase activity
MKS87_07215	COG3212	peptidase
MKS87_07220	COG3212	peptidase
MKS87_07230	COG2239	Acts as a magnesium transporter
MKS87_07235	COG0789	Transcriptional regulator
MKS87_07250	COG1846	Transcriptional regulator
MKS87_07255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKS87_07260	COG0726	polysaccharide deacetylase
MKS87_07265	COG1408	metallophosphoesterase
MKS87_07275	COG0463	Glycosyl transferase, family 2
MKS87_07280	COG1793	dna ligase
MKS87_07280	COG3285	dna ligase
MKS87_07285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MKS87_07290	COG5001	Diguanylate cyclase
MKS87_07290	COG3300	MHYT domain
MKS87_07295	COG0586	Pfam SNARE associated Golgi protein
MKS87_07300	COG0861	Integral membrane protein TerC family
MKS87_07305	COG1191	sigma factor activity
MKS87_07325	COG0501	Belongs to the peptidase M48B family
MKS87_07330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKS87_07345	COG3594	Acyltransferase
MKS87_07350	COG5002	protein histidine kinase activity
MKS87_07355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKS87_07365	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MKS87_07370	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MKS87_07375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MKS87_07380	COG0436	Aminotransferase
MKS87_07385	COG1850	ribulose-bisphosphate carboxylase activity
MKS87_07390	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MKS87_07395	COG0235	Class ii aldolase
MKS87_07400	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MKS87_07405	COG3339	Conserved Protein
MKS87_07420	COG3852	Histidine kinase
MKS87_07425	COG1846	Transcriptional regulator
MKS87_07430	COG1360	Flagellar Motor Protein
MKS87_07435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MKS87_07440	COG0542	response to heat
MKS87_07445	COG3949	Membrane
MKS87_07450	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MKS87_07455	COG0720	synthase
MKS87_07460	COG0602	queuosine metabolic process
MKS87_07465	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MKS87_07470	COG1733	regulation of RNA biosynthetic process
MKS87_07475	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_07480	COG1388	LysM domain
MKS87_07480	COG4641	Protein conserved in bacteria
MKS87_07485	COG1388	LysM domain
MKS87_07490	COG3858	chitin binding
MKS87_07495	COG3858	chitin binding
MKS87_07505	COG4873	Protein conserved in bacteria
MKS87_07515	COG3773	Cell wall hydrolase
MKS87_07520	COG2244	polysaccharide biosynthetic process
MKS87_07525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_07530	COG2217	Heavy metal translocating P-type atpase
MKS87_07540	COG0006	proline dipeptidase activity
MKS87_07545	COG1609	Transcriptional regulator
MKS87_07550	COG3711	transcriptional antiterminator
MKS87_07555	COG2190	(PTS) system
MKS87_07555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_07555	COG1263	PTS System
MKS87_07560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_07565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKS87_07575	COG1533	DNA photolyase activity
MKS87_07580	COG0456	acetyltransferase
MKS87_07585	COG0840	transmembrane signaling receptor activity
MKS87_07590	COG2084	Dehydrogenase
MKS87_07595	COG2340	Cysteine-rich secretory protein family
MKS87_07600	COG0768	penicillin binding
MKS87_07605	COG4191	Histidine kinase
MKS87_07610	COG0436	Aminotransferase
MKS87_07620	COG0784	Response regulator, receiver
MKS87_07620	COG0835	chemotaxis
MKS87_07630	COG2814	Major facilitator Superfamily
MKS87_07635	COG1376	ErfK ybiS ycfS ynhG family protein
MKS87_07640	COG1408	metallophosphoesterase
MKS87_07645	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_07650	COG2200	EAL domain
MKS87_07655	COG4703	Protein of unknown function (DUF1797)
MKS87_07660	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MKS87_07670	COG0517	IMP dehydrogenase activity
MKS87_07675	COG0583	DNA-binding transcription factor activity
MKS87_07680	COG0716	FMN binding
MKS87_07690	COG0716	FMN binding
MKS87_07695	COG2171	N-acyltransferase activity
MKS87_07700	COG1473	amidohydrolase
MKS87_07710	COG0668	transmembrane transport
MKS87_07715	COG0450	alkyl hydroperoxide reductase
MKS87_07720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_07735	COG0746	molybdenum cofactor guanylyltransferase activity
MKS87_07740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MKS87_07745	COG0303	'Molybdopterin
MKS87_07750	COG1763	Mo-molybdopterin cofactor biosynthetic process
MKS87_07755	COG0314	molybdopterin synthase activity
MKS87_07760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MKS87_07765	COG1132	(ABC) transporter
MKS87_07770	COG1132	(ABC) transporter
MKS87_07780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKS87_07785	COG1136	(ABC) transporter
MKS87_07790	COG0577	efflux transmembrane transporter activity
MKS87_07795	COG1349	DNA-binding transcription factor activity
MKS87_07800	COG1105	Belongs to the carbohydrate kinase PfkB family
MKS87_07805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKS87_07805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MKS87_07805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_07810	COG0681	Belongs to the peptidase S26 family
MKS87_07820	COG0488	(ABC) transporter
MKS87_07825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKS87_07830	COG2309	aminopeptidase activity
MKS87_07840	COG1077	Cell shape determining protein MreB Mrl
MKS87_07845	COG2002	toxin-antitoxin pair type II binding
MKS87_07850	COG3852	Histidine kinase
MKS87_07855	COG2105	PFAM AIG2 family protein
MKS87_07855	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MKS87_07860	COG0569	domain protein
MKS87_07865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKS87_07870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKS87_07875	COG5503	Protein of unknown function (DUF1447)
MKS87_07880	COG0561	phosphatase activity
MKS87_07885	COG0242	peptide deformylase activity
MKS87_07895	COG0497	DNA recombination
MKS87_07900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MKS87_07905	COG0022	dehydrogenase e1 component
MKS87_07910	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKS87_07915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKS87_07920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_07930	COG1982	Orn Lys Arg decarboxylase major
MKS87_07935	COG4476	Belongs to the UPF0223 family
MKS87_07940	COG4493	Belongs to the UPF0637 family
MKS87_07950	COG0483	inositol monophosphate 1-phosphatase activity
MKS87_07960	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKS87_07980	COG1595	DNA-templated transcription, initiation
MKS87_08000	COG1217	gtp-binding protein TYPA
MKS87_08010	COG4896	Protein conserved in bacteria
MKS87_08020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MKS87_08025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKS87_08030	COG2066	Belongs to the glutaminase family
MKS87_08035	COG4838	Belongs to the UPF0358 family
MKS87_08040	COG0772	Belongs to the SEDS family
MKS87_08045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKS87_08050	COG1612	heme a metabolic process
MKS87_08055	COG0109	protoheme IX farnesyltransferase activity
MKS87_08060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MKS87_08060	COG2010	Cytochrome c
MKS87_08065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKS87_08070	COG1845	cytochrome c oxidase, subunit III
MKS87_08075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MKS87_08080	COG3336	cytochrome c oxidase
MKS87_08090	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MKS87_08095	COG2340	Cysteine-rich secretory protein family
MKS87_08110	COG3679	Belongs to the UPF0342 family
MKS87_08115	COG4471	UPF0298 protein
MKS87_08120	COG0742	ribosomal rna small subunit methyltransferase
MKS87_08125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKS87_08130	COG3314	Sporulation integral membrane protein YlbJ
MKS87_08135	COG1752	Esterase of the alpha-beta hydrolase superfamily
MKS87_08140	COG3480	Lon protease (S16) C-terminal proteolytic domain
MKS87_08145	COG1323	Belongs to the UPF0348 family
MKS87_08155	COG1399	metal-binding, possibly nucleic acid-binding protein
MKS87_08170	COG0454	-acetyltransferase
MKS87_08175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKS87_08180	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MKS87_08185	COG2001	Belongs to the MraZ family
MKS87_08190	COG0275	rRNA processing
MKS87_08195	COG4839	cell division protein FtsL
MKS87_08200	COG0768	penicillin binding
MKS87_08205	COG0768	penicillin binding
MKS87_08210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKS87_08215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKS87_08220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKS87_08225	COG0772	Belongs to the SEDS family
MKS87_08230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKS87_08235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MKS87_08240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MKS87_08245	COG3879	Bacterial protein of unknown function (DUF881)
MKS87_08250	COG3879	Bacterial protein of unknown function (DUF881)
MKS87_08255	COG3856	small basic protein
MKS87_08260	COG0849	cell division
MKS87_08265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKS87_08285	COG4412	M6 family metalloprotease domain protein
MKS87_08285	COG1404	Belongs to the peptidase S8 family
MKS87_08295	COG1191	sigma factor activity
MKS87_08300	COG1191	sigma factor activity
MKS87_08305	COG1119	ATPase activity
MKS87_08310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MKS87_08315	COG1873	PFAM PRC-barrel domain
MKS87_08320	COG1496	oxidoreductase activity
MKS87_08325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKS87_08330	COG1799	cell septum assembly
MKS87_08335	COG0762	integral membrane protein
MKS87_08340	COG2302	S4 RNA-binding domain
MKS87_08345	COG3599	regulation of cell shape
MKS87_08350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKS87_08355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MKS87_08360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKS87_08365	COG0564	pseudouridine synthase activity
MKS87_08370	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKS87_08375	COG2233	PERMEase
MKS87_08380	COG0540	Belongs to the ATCase OTCase family
MKS87_08385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MKS87_08390	COG0505	Belongs to the CarA family
MKS87_08395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MKS87_08400	COG0543	2 iron, 2 sulfur cluster binding
MKS87_08405	COG0167	dihydroorotate dehydrogenase activity
MKS87_08410	COG0284	orotidine-5'-phosphate decarboxylase activity
MKS87_08415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKS87_08420	COG0175	sulfate reduction
MKS87_08425	COG0306	phosphate transporter
MKS87_08430	COG2046	Belongs to the sulfate adenylyltransferase family
MKS87_08435	COG0529	Catalyzes the synthesis of activated sulfate
MKS87_08440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MKS87_08445	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MKS87_08450	COG1648	precorrin-2 dehydrogenase activity
MKS87_08455	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MKS87_08460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MKS87_08465	COG1561	YicC-like family, N-terminal region
MKS87_08475	COG0194	GDP metabolic process
MKS87_08480	COG1758	RNA polymerase activity
MKS87_08485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKS87_08490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKS87_08495	COG0242	peptide deformylase activity
MKS87_08500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKS87_08505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKS87_08505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKS87_08510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MKS87_08515	COG0631	protein serine/threonine phosphatase activity
MKS87_08520	COG2815	serine threonine protein kinase
MKS87_08520	COG0515	serine threonine protein kinase
MKS87_08525	COG1162	GTPase activity
MKS87_08530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MKS87_08535	COG1564	THIamine pyrophosphokinase
MKS87_08545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MKS87_08550	COG1302	Protein conserved in bacteria
MKS87_08555	COG1461	Dihydroxyacetone kinase
MKS87_08560	COG1760	l-serine dehydratase
MKS87_08565	COG1760	l-serine dehydratase
MKS87_08570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKS87_08575	COG2050	protein possibly involved in aromatic compounds catabolism
MKS87_08575	COG1349	DNA-binding transcription factor activity
MKS87_08580	COG0416	fatty acid biosynthetic process
MKS87_08585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MKS87_08590	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_08600	COG0571	ribonuclease III activity
MKS87_08605	COG1196	nuclear chromosome segregation
MKS87_08610	COG0552	protein localization to endoplasmic reticulum
MKS87_08620	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKS87_08625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKS87_08630	COG0228	four-way junction DNA binding
MKS87_08635	COG1837	Belongs to the UPF0109 family
MKS87_08645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKS87_08650	COG0336	Belongs to the RNA methyltransferase TrmD family
MKS87_08655	COG0335	large ribosomal subunit rRNA binding
MKS87_08660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKS87_08665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKS87_08675	COG2257	FlhB HrpN YscU SpaS Family
MKS87_08680	COG0045	succinate-CoA ligase (ADP-forming) activity
MKS87_08685	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MKS87_08690	COG0758	DNA mediated transformation
MKS87_08695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKS87_08700	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKS87_08705	COG4974	Belongs to the 'phage' integrase family
MKS87_08710	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKS87_08715	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKS87_08720	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MKS87_08725	COG1815	bacterial-type flagellum-dependent cell motility
MKS87_08730	COG1558	bacterial-type flagellum-dependent cell motility
MKS87_08735	COG1677	Flagellar hook-basal body complex protein FliE
MKS87_08740	COG1766	The M ring may be actively involved in energy transduction
MKS87_08745	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKS87_08750	COG1317	bacterial-type flagellum organization
MKS87_08755	COG1157	protein secretion by the type III secretion system
MKS87_08760	COG2882	bacterial-type flagellum organization
MKS87_08765	COG3334	PFAM MgtE intracellular
MKS87_08770	COG3144	bacterial-type flagellum assembly
MKS87_08775	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MKS87_08780	COG4786	Flagellar basal body rod
MKS87_08785	COG1582	Flagellar protein (FlbD)
MKS87_08790	COG1580	Controls the rotational direction of flagella during chemotaxis
MKS87_08795	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKS87_08800	COG1776	CheC inhibitor of MCP methylation
MKS87_08800	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKS87_08805	COG2201	protein-glutamate methylesterase activity
MKS87_08810	COG3190	flagellar
MKS87_08815	COG1338	Plays a role in the flagellum-specific transport system
MKS87_08820	COG1987	bacterial-type flagellum assembly
MKS87_08825	COG1684	flagellar biosynthetic protein fliR
MKS87_08830	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKS87_08835	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKS87_08840	COG1419	protein localization to endoplasmic reticulum
MKS87_08845	COG0455	bacterial-type flagellum organization
MKS87_08850	COG2201	protein-glutamate methylesterase activity
MKS87_08855	COG0643	Histidine kinase
MKS87_08855	COG2198	Histidine kinase
MKS87_08860	COG0835	chemotaxis
MKS87_08865	COG1776	CheC inhibitor of MCP methylation
MKS87_08870	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MKS87_08875	COG1191	sigma factor activity
MKS87_08885	COG0052	Belongs to the universal ribosomal protein uS2 family
MKS87_08890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKS87_08895	COG0528	UMP kinase activity
MKS87_08900	COG0233	cytoplasmic translational termination
MKS87_08905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKS87_08910	COG4589	Belongs to the CDS family
MKS87_08915	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MKS87_08920	COG0750	zinc metalloprotease
MKS87_08925	COG0442	prolyl-tRNA aminoacylation
MKS87_08930	COG2176	DNA-directed DNA polymerase activity
MKS87_08935	COG0779	Required for maturation of 30S ribosomal subunits
MKS87_08940	COG0195	Participates in both transcription termination and antitermination
MKS87_08945	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MKS87_08950	COG1358	cellular component organization or biogenesis
MKS87_08955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKS87_08960	COG1550	Protein conserved in bacteria
MKS87_08965	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKS87_08970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKS87_08975	COG0196	riboflavin kinase activity
MKS87_08980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKS87_08985	COG1185	polyribonucleotide nucleotidyltransferase activity
MKS87_08990	COG0726	polysaccharide deacetylase
MKS87_08995	COG0612	Peptidase, M16
MKS87_09000	COG1873	PFAM PRC-barrel domain
MKS87_09005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKS87_09010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKS87_09015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKS87_09020	COG0527	aspartate kinase activity
MKS87_09025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKS87_09030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKS87_09035	COG0740	serine-type endopeptidase activity
MKS87_09045	COG1674	ftsk spoiiie
MKS87_09045	COG4980	gas vesicle protein
MKS87_09050	COG2188	Transcriptional regulator
MKS87_09055	COG2814	Major facilitator Superfamily
MKS87_09060	COG0612	Peptidase, M16
MKS87_09065	COG0612	Peptidase, M16
MKS87_09070	COG0300	oxidoreductase activity
MKS87_09085	COG1426	Protein conserved in bacteria
MKS87_09090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKS87_09095	COG1546	Belongs to the CinA family
MKS87_09095	COG1058	Belongs to the CinA family
MKS87_09100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKS87_09105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MKS87_09110	COG1418	mRNA catabolic process
MKS87_09115	COG1692	metallophosphoesterase
MKS87_09120	COG2359	stage V sporulation protein S
MKS87_09125	COG1063	alcohol dehydrogenase
MKS87_09130	COG0156	8-amino-7-oxononanoate synthase activity
MKS87_09135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKS87_09140	COG4550	Control of competence regulator ComK, YlbF/YmcA
MKS87_09150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKS87_09155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKS87_09170	COG3226	Transcriptional regulator
MKS87_09175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_09185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MKS87_09190	COG3321	synthase
MKS87_09195	COG2070	2-Nitropropane dioxygenase
MKS87_09195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MKS87_09200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKS87_09205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MKS87_09210	COG3425	synthase
MKS87_09215	COG1024	Enoyl-CoA hydratase
MKS87_09220	COG1024	Enoyl-CoA hydratase
MKS87_09225	COG0318	PFAM AMP-dependent synthetase and ligase
MKS87_09225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09225	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_09225	COG3321	synthase
MKS87_09225	COG0300	oxidoreductase activity
MKS87_09230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKS87_09230	COG3321	synthase
MKS87_09230	COG4221	oxidoreductase activity
MKS87_09230	COG0300	oxidoreductase activity
MKS87_09235	COG3321	synthase
MKS87_09235	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_09235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKS87_09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKS87_09235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09240	COG4221	oxidoreductase activity
MKS87_09240	COG3321	synthase
MKS87_09240	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_09245	COG3321	synthase
MKS87_09245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MKS87_09245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKS87_09245	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MKS87_09250	COG2124	cytochrome p450
MKS87_09260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_09265	COG1404	Belongs to the peptidase S8 family
MKS87_09275	COG4195	phage-related replication protein
MKS87_09280	COG1764	response to oxidative stress
MKS87_09285	COG2076	Multidrug Resistance protein
MKS87_09290	COG2076	Multidrug Resistance protein
MKS87_09305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKS87_09310	COG1923	regulation of RNA biosynthetic process
MKS87_09325	COG1780	Probably involved in ribonucleotide reductase function
MKS87_09330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKS87_09335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKS87_09340	COG4112	unkown
MKS87_09345	COG0860	N-Acetylmuramoyl-L-alanine amidase
MKS87_09350	COG0464	growth
MKS87_09355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKS87_09360	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MKS87_09365	COG0789	Transcriptional regulator
MKS87_09370	COG0174	glutamine synthetase
MKS87_09410	COG1598	PFAM Uncharacterised protein family UPF0150
MKS87_09490	COG0463	Glycosyl transferase, family 2
MKS87_09505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_09520	COG3655	Transcriptional regulator
MKS87_09535	COG0135	phosphoribosylanthranilate isomerase activity
MKS87_09550	COG2211	Major facilitator Superfamily
MKS87_09555	COG3507	Belongs to the glycosyl hydrolase 43 family
MKS87_09560	COG1940	carbohydrate kinase activity
MKS87_09565	COG2115	Belongs to the xylose isomerase family
MKS87_09570	COG1070	Carbohydrate kinase
MKS87_09580	COG1525	nuclease
MKS87_09585	COG2814	Major facilitator Superfamily
MKS87_09590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKS87_09600	COG0756	dUTP diphosphatase activity
MKS87_09640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKS87_09655	COG3832	glyoxalase III activity
MKS87_09670	COG0697	spore germination
MKS87_09675	COG0531	amino acid
MKS87_09705	COG4195	phage-related replication protein
MKS87_09715	COG0346	lactoylglutathione lyase activity
MKS87_09725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKS87_09730	COG1388	LysM domain
MKS87_09735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MKS87_09740	COG4224	UPF0291 protein
MKS87_09745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKS87_09755	COG3763	UPF0154 protein
MKS87_09765	COG0785	Cytochrome C biogenesis protein
MKS87_09770	COG2201	protein-glutamate methylesterase activity
MKS87_09775	COG4846	Membrane protein involved in cytochrome C biogenesis
MKS87_09785	COG0071	Belongs to the small heat shock protein (HSP20) family
MKS87_09800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MKS87_09805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_09825	COG0824	Thioesterase
MKS87_09835	COG4841	protein insertion into membrane
MKS87_09840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MKS87_09845	COG1832	CoA-binding protein
MKS87_09850	COG0187	DNA topoisomerase II activity
MKS87_09855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKS87_09865	COG1115	amino acid carrier protein
MKS87_09870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MKS87_09880	COG5520	Belongs to the glycosyl hydrolase 30 family
MKS87_09885	COG3507	Belongs to the glycosyl hydrolase 43 family
MKS87_09890	COG2246	polysaccharide biosynthetic process
MKS87_09895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MKS87_09900	COG0586	Pfam SNARE associated Golgi protein
MKS87_09905	COG2404	hydrolase activity, acting on ester bonds
MKS87_09910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MKS87_09915	COG1024	Enoyl-CoA hydratase
MKS87_09920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKS87_09925	COG0511	ligase activity, forming carbon-carbon bonds
MKS87_09930	COG0439	Biotin carboxylase
MKS87_09935	COG0318	PFAM AMP-dependent synthetase and ligase
MKS87_09940	COG1960	acyl-CoA dehydrogenase activity
MKS87_09955	COG1649	PFAM Uncharacterised BCR, COG1649
MKS87_09965	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MKS87_09965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_09990	COG2027	D-alanyl-D-alanine carboxypeptidase
MKS87_09995	COG2017	converts alpha-aldose to the beta-anomer
MKS87_10000	COG0534	Mate efflux family protein
MKS87_10015	COG0582	viral genome integration into host DNA
MKS87_10020	COG0166	Belongs to the GPI family
MKS87_10025	COG0405	Gamma-glutamyltransferase
MKS87_10030	COG0583	DNA-binding transcription factor activity
MKS87_10035	COG0604	alcohol dehydrogenase
MKS87_10040	COG0493	'glutamate synthase
MKS87_10045	COG0070	glutamate synthase
MKS87_10045	COG0069	glutamate synthase activity
MKS87_10045	COG0067	glutamate synthase
MKS87_10050	COG0583	DNA-binding transcription factor activity
MKS87_10055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKS87_10060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKS87_10070	COG0300	oxidoreductase activity
MKS87_10075	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKS87_10085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKS87_10105	COG2814	Major facilitator Superfamily
MKS87_10110	COG1070	Carbohydrate kinase
MKS87_10115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKS87_10120	COG0243	molybdopterin cofactor binding
MKS87_10155	COG5278	phosphoserine phosphatase activity
MKS87_10155	COG0840	transmembrane signaling receptor activity
MKS87_10160	COG2368	4-hydroxyphenylacetate
MKS87_10165	COG4305	rare lipoprotein A
MKS87_10170	COG3619	membrane
MKS87_10175	COG3866	Pectate lyase
MKS87_10180	COG2135	peptidase activity
MKS87_10200	COG0456	acetyltransferase
MKS87_10220	COG2720	vancomycin resistance protein
MKS87_10235	COG3739	integral membrane protein
MKS87_10240	COG0583	DNA-binding transcription factor activity
MKS87_10245	COG0697	spore germination
MKS87_10255	COG0693	protein deglycase activity
MKS87_10260	COG2367	Beta-lactamase
MKS87_10280	COG3848	Pyruvate phosphate dikinase
MKS87_10280	COG0574	Belongs to the PEP-utilizing enzyme family
MKS87_10285	COG0726	polysaccharide deacetylase
MKS87_10290	COG2314	TM2 domain
MKS87_10295	COG1396	sequence-specific DNA binding
MKS87_10415	COG0457	Tetratricopeptide repeat
MKS87_10450	COG5444	nuclease activity
MKS87_10455	COG4282	regulation of fungal-type cell wall biogenesis
MKS87_10460	COG1231	oxidoreductase activity
MKS87_10465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKS87_10470	COG2207	Transcriptional regulator
MKS87_10470	COG0662	Cupin 2, conserved barrel domain protein
MKS87_10475	COG0456	acetyltransferase
MKS87_10480	COG1309	transcriptional regulator
MKS87_10485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_10490	COG3708	Transcriptional regulator
MKS87_10495	COG2378	regulation of single-species biofilm formation
MKS87_10505	COG0640	Transcriptional regulator
MKS87_10510	COG0741	lytic transglycosylase activity
MKS87_10515	COG2322	membrane
MKS87_10530	COG1619	proteins homologs of microcin C7 resistance protein MccF
MKS87_10535	COG3239	Fatty acid desaturase
MKS87_10540	COG4585	Histidine kinase
MKS87_10545	COG2197	response regulator
MKS87_10550	COG3584	3D domain protein
MKS87_10550	COG1388	LysM domain
MKS87_10555	COG0514	ATP-dependent DNA helicase (RecQ)
MKS87_10565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKS87_10570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MKS87_10585	COG0071	Belongs to the small heat shock protein (HSP20) family
MKS87_10610	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_10615	COG1657	PFAM Prenyltransferase squalene oxidase
MKS87_10620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKS87_10625	COG0733	neurotransmitter:sodium symporter activity
MKS87_10630	COG0385	Bile acid
MKS87_10635	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKS87_10640	COG0567	Dehydrogenase, E1 component
MKS87_10645	COG4548	von Willebrand factor, type A
MKS87_10650	COG0714	Associated with various cellular activities
MKS87_10655	COG2032	superoxide dismutase activity
MKS87_10660	COG0791	NLP P60 protein
MKS87_10660	COG1388	LysM domain
MKS87_10665	COG1819	glycosyl
MKS87_10670	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKS87_10675	COG0534	Mate efflux family protein
MKS87_10680	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_10685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MKS87_10690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MKS87_10700	COG2962	Rard protein
MKS87_10720	COG1942	4-Oxalocrotonate Tautomerase
MKS87_10725	COG1733	regulation of RNA biosynthetic process
MKS87_10730	COG0778	Nitroreductase
MKS87_10735	COG0400	carboxylic ester hydrolase activity
MKS87_10740	COG0346	lactoylglutathione lyase activity
MKS87_10750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKS87_10755	COG0793	Belongs to the peptidase S41A family
MKS87_10755	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_10760	COG2226	methyltransferase
MKS87_10770	COG1876	peptidase activity
MKS87_10775	COG0813	purine-nucleoside phosphorylase activity
MKS87_10790	COG0671	phosphoesterase, PA-phosphatase related
MKS87_10810	COG4479	Belongs to the UPF0346 family
MKS87_10830	COG3331	DNA recombination
MKS87_10910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKS87_10940	COG0756	dUTP diphosphatase activity
MKS87_10955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_10985	COG1780	Probably involved in ribonucleotide reductase function
MKS87_11085	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MKS87_11090	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKS87_11115	COG3584	3D domain protein
MKS87_11120	COG0587	DNA-directed DNA polymerase activity
MKS87_11125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MKS87_11130	COG0358	DNA primase activity
MKS87_11135	COG0305	Participates in initiation and elongation during chromosome replication
MKS87_11145	COG2887	Belongs to the helicase family. UvrD subfamily
MKS87_11175	COG5434	Belongs to the glycosyl hydrolase 28 family
MKS87_11175	COG3420	alginic acid biosynthetic process
MKS87_11180	COG4195	phage-related replication protein
MKS87_11195	COG2135	peptidase activity
MKS87_11200	COG1793	dna ligase
MKS87_11245	COG4474	Belongs to the UPF0398 family
MKS87_11265	COG3645	SOS response
MKS87_11265	COG3646	Phage regulatory protein
MKS87_11300	COG3655	Transcriptional regulator
MKS87_11315	COG0582	viral genome integration into host DNA
MKS87_11395	COG3655	Transcriptional regulator
MKS87_11505	COG1395	domain, Protein
MKS87_11520	COG0776	regulation of translation
MKS87_11560	COG4373	Mu-like prophage FluMu protein gp28
MKS87_11660	COG0582	viral genome integration into host DNA
MKS87_11680	COG0739	heme binding
MKS87_11680	COG0741	lytic transglycosylase activity
MKS87_11680	COG1196	nuclear chromosome segregation
MKS87_11690	COG2433	Pfam Transposase IS66
MKS87_11705	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKS87_11720	COG0457	Tetratricopeptide repeat
MKS87_11730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKS87_11755	COG5444	nuclease activity
MKS87_11765	COG4282	regulation of fungal-type cell wall biogenesis
MKS87_11775	COG1525	nuclease
MKS87_11785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MKS87_11795	COG0456	acetyltransferase
MKS87_11800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MKS87_11805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MKS87_11810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKS87_11815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MKS87_11830	COG0456	acetyltransferase
MKS87_11835	COG0463	Glycosyl transferase, family 2
MKS87_11850	COG4641	Protein conserved in bacteria
MKS87_11855	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
MKS87_11860	COG1086	Polysaccharide biosynthesis protein
MKS87_11865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKS87_11870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKS87_11875	COG1846	Transcriptional regulator
MKS87_11880	COG0534	Mate efflux family protein
MKS87_11890	COG4698	Protein conserved in bacteria
MKS87_11895	COG2755	lipolytic protein G-D-S-L family
MKS87_11900	COG1999	signal sequence binding
MKS87_11910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MKS87_11915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MKS87_11920	COG1272	protein, Hemolysin III
MKS87_11925	COG0204	Acyl-transferase
MKS87_11930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKS87_11935	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKS87_11940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MKS87_11950	COG2521	methyltransferase
MKS87_11950	COG2136	Putative SAM-dependent methyltransferase
MKS87_11960	COG0129	dihydroxy-acid dehydratase activity
MKS87_11965	COG1413	lyase activity
MKS87_11970	COG1418	mRNA catabolic process
MKS87_11975	COG0386	Belongs to the glutathione peroxidase family
MKS87_11980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MKS87_11985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKS87_11995	COG1278	Cold shock
MKS87_12015	COG0328	RNA-DNA hybrid ribonuclease activity
MKS87_12020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKS87_12025	COG0328	RNA-DNA hybrid ribonuclease activity
MKS87_12035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKS87_12050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKS87_12060	COG1755	Isoprenylcysteine carboxyl methyltransferase
MKS87_12065	COG3424	synthase
MKS87_12070	COG2233	PERMEase
MKS87_12075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKS87_12080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MKS87_12090	COG0800	Aldolase
MKS87_12095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKS87_12100	COG1609	Transcriptional regulator
MKS87_12105	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MKS87_12110	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_12115	COG1199	ATP-dependent helicase activity
MKS87_12130	COG0116	Belongs to the methyltransferase superfamily
MKS87_12145	COG4474	Belongs to the UPF0398 family
MKS87_12160	COG3359	exonuclease
MKS87_12165	COG1111	helicase
MKS87_12165	COG1205	dead DEAH box helicase
MKS87_12170	COG2190	(PTS) system
MKS87_12175	COG0071	Belongs to the small heat shock protein (HSP20) family
MKS87_12210	COG3331	DNA recombination
MKS87_12215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKS87_12215	COG4499	WXG100 protein secretion system (Wss), protein YukC
MKS87_12225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKS87_12230	COG3935	DnaD domain protein
MKS87_12235	COG0017	Asparaginyl-tRNA synthetase
MKS87_12240	COG0436	Aminotransferase
MKS87_12245	COG5353	protein conserved in bacteria
MKS87_12255	COG1199	ATP-dependent helicase activity
MKS87_12255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MKS87_12260	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MKS87_12265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MKS87_12270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MKS87_12275	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MKS87_12275	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MKS87_12280	COG0617	tRNA 3'-terminal CCA addition
MKS87_12285	COG0438	transferase activity, transferring glycosyl groups
MKS87_12290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MKS87_12295	COG1803	Methylglyoxal synthase
MKS87_12300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MKS87_12305	COG1694	Mazg nucleotide pyrophosphohydrolase
MKS87_12310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKS87_12320	COG4347	Protein of unknown function (DUF1405)
MKS87_12325	COG2010	Cytochrome c
MKS87_12325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MKS87_12330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MKS87_12335	COG0723	plastoquinol--plastocyanin reductase activity
MKS87_12345	COG5582	Belongs to the UPF0302 family
MKS87_12350	COG0457	Tetratricopeptide repeat
MKS87_12355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MKS87_12360	COG0287	Prephenate dehydrogenase
MKS87_12365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKS87_12370	COG0159	tryptophan synthase activity
MKS87_12375	COG0133	tryptophan synthase activity
MKS87_12380	COG0135	phosphoribosylanthranilate isomerase activity
MKS87_12390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKS87_12395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKS87_12400	COG4401	Chorismate mutase type I
MKS87_12405	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKS87_12410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKS87_12415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MKS87_12420	COG0105	UTP biosynthetic process
MKS87_12425	COG0142	geranyltranstransferase activity
MKS87_12430	COG2226	methyltransferase
MKS87_12435	COG0142	geranyltranstransferase activity
MKS87_12445	COG0302	gtp cyclohydrolase
MKS87_12450	COG0776	regulation of translation
MKS87_12455	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKS87_12470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MKS87_12475	COG1160	GTP binding
MKS87_12500	COG1304	FMN binding
MKS87_12505	COG0539	negative regulation of cytoplasmic translation
MKS87_12510	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MKS87_12520	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MKS87_12525	COG2959	enzyme of heme biosynthesis
MKS87_12530	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_12530	COG3773	Cell wall hydrolase
MKS87_12535	COG2339	peptidase activity
MKS87_12540	COG0492	ferredoxin-NADP+ reductase activity
MKS87_12545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MKS87_12550	COG4862	establishment of competence for transformation
MKS87_12555	COG1408	metallophosphoesterase
MKS87_12565	COG1388	LysM domain
MKS87_12570	COG1266	CAAX protease self-immunity
MKS87_12575	COG0514	ATP-dependent DNA helicase (RecQ)
MKS87_12580	COG4955	Helix-turn-helix domain
MKS87_12585	COG1141	Ferredoxin
MKS87_12590	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKS87_12595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MKS87_12600	COG0710	3-dehydroquinate dehydratase activity
MKS87_12610	COG1595	DNA-templated transcription, initiation
MKS87_12615	COG5002	protein histidine kinase activity
MKS87_12620	COG0745	RESPONSE REGULATOR receiver
MKS87_12625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MKS87_12630	COG1333	cytochrome c biogenesis protein
MKS87_12635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_12640	COG1187	pseudouridine synthase activity
MKS87_12645	COG0700	Nucleoside recognition
MKS87_12650	COG2715	membrane protein required for spore maturation
MKS87_12655	COG1686	Belongs to the peptidase S11 family
MKS87_12665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKS87_12670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKS87_12675	COG1547	Domain of unknown function (DUF309)
MKS87_12680	COG0456	acetyltransferase
MKS87_12685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MKS87_12690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKS87_12690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKS87_12695	COG0307	riboflavin synthase, alpha
MKS87_12700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKS87_12700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKS87_12710	COG0681	Belongs to the peptidase S26 family
MKS87_12720	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MKS87_12740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKS87_12745	COG4086	secreted protein
MKS87_12750	COG0019	diaminopimelate decarboxylase activity
MKS87_12755	COG0697	spore germination
MKS87_12770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKS87_12790	COG1191	sigma factor activity
MKS87_12795	COG2172	sigma factor antagonist activity
MKS87_12800	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_12805	COG1686	Belongs to the peptidase S11 family
MKS87_12810	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MKS87_12815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MKS87_12820	COG4974	Belongs to the 'phage' integrase family
MKS87_12830	COG0735	belongs to the Fur family
MKS87_12835	COG1300	Membrane
MKS87_12845	COG0281	malic enzyme
MKS87_12850	COG1757	Na H antiporter
MKS87_12855	COG1027	Aspartate ammonia-lyase
MKS87_12860	COG0252	asparaginase activity
MKS87_12865	COG1396	sequence-specific DNA binding
MKS87_12870	COG1379	DNA repair
MKS87_12875	COG0494	nUDIX hydrolase
MKS87_12885	COG0667	Aldo Keto reductase
MKS87_12895	COG1073	alpha beta
MKS87_12905	COG4918	Iron-sulphur cluster biosynthesis
MKS87_12910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKS87_12910	COG0456	acetyltransferase
MKS87_12915	COG2329	Antibiotic biosynthesis monooxygenase
MKS87_12920	COG0456	acetyltransferase
MKS87_12930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKS87_12940	COG2211	Major facilitator Superfamily
MKS87_12950	COG0346	lactoylglutathione lyase activity
MKS87_12955	COG1072	(Pantothenic acid kinase))
MKS87_12960	COG3048	D-serine ammonia-lyase activity
MKS87_12965	COG0300	oxidoreductase activity
MKS87_12970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_12975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKS87_12980	COG4187	Peptidase family M20/M25/M40
MKS87_12985	COG1902	pentaerythritol trinitrate reductase activity
MKS87_12990	COG0596	Alpha beta hydrolase
MKS87_13000	COG1234	tRNA 3'-trailer cleavage
MKS87_13005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKS87_13010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKS87_13015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKS87_13025	COG0706	membrane insertase activity
MKS87_13030	COG3361	conserved protein (COG2071)
MKS87_13035	COG2195	Cleaves the N-terminal amino acid of tripeptides
MKS87_13040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MKS87_13045	COG0346	lactoylglutathione lyase activity
MKS87_13055	COG1376	ErfK ybiS ycfS ynhG family protein
MKS87_13060	COG4129	membrane
MKS87_13065	COG1126	abc transporter atp-binding protein
MKS87_13070	COG0765	amino acid transport
MKS87_13075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKS87_13085	COG1597	lipid kinase activity
MKS87_13090	COG2814	Major facilitator Superfamily
MKS87_13095	COG0789	Transcriptional regulator
MKS87_13095	COG4978	Transcriptional regulator
MKS87_13100	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKS87_13105	COG0022	dehydrogenase e1 component
MKS87_13110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MKS87_13115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKS87_13120	COG3426	butyrate kinase activity
MKS87_13125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MKS87_13130	COG0280	phosphate acetyltransferase
MKS87_13135	COG3829	transcription factor binding
MKS87_13135	COG3290	protein histidine kinase activity
MKS87_13145	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MKS87_13150	COG2079	MmgE PrpD family protein
MKS87_13155	COG0372	Belongs to the citrate synthase family
MKS87_13160	COG1960	acyl-CoA dehydrogenase activity
MKS87_13165	COG1250	3-hydroxyacyl-CoA dehydrogenase
MKS87_13170	COG0183	Belongs to the thiolase family
MKS87_13175	COG0584	glycerophosphoryl diester phosphodiesterase
MKS87_13180	COG0860	N-Acetylmuramoyl-L-alanine amidase
MKS87_13195	COG1902	pentaerythritol trinitrate reductase activity
MKS87_13200	COG0745	RESPONSE REGULATOR receiver
MKS87_13205	COG0750	zinc metalloprotease
MKS87_13210	COG0497	DNA recombination
MKS87_13215	COG1438	arginine binding
MKS87_13220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MKS87_13225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKS87_13230	COG0142	geranyltranstransferase activity
MKS87_13235	COG1722	exodeoxyribonuclease VII activity
MKS87_13240	COG1570	exodeoxyribonuclease VII activity
MKS87_13245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKS87_13250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKS87_13255	COG1302	Protein conserved in bacteria
MKS87_13260	COG0439	Biotin carboxylase
MKS87_13265	COG0511	ligase activity, forming carbon-carbon bonds
MKS87_13305	COG3854	ATPases associated with a variety of cellular activities
MKS87_13315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKS87_13320	COG0006	proline dipeptidase activity
MKS87_13325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MKS87_13335	COG3872	metal-dependent enzyme
MKS87_13345	COG1752	Esterase of the alpha-beta hydrolase superfamily
MKS87_13350	COG1321	iron dependent repressor
MKS87_13355	COG0095	Lipoate-protein ligase
MKS87_13360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKS87_13365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKS87_13370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKS87_13375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MKS87_13380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MKS87_13395	COG1396	sequence-specific DNA binding
MKS87_13405	COG0681	Belongs to the peptidase S26 family
MKS87_13430	COG4940	Competence protein ComGF
MKS87_13440	COG4970	Tfp pilus assembly protein FimT
MKS87_13445	COG4537	Required for transformation and DNA binding
MKS87_13450	COG1459	type II secretion system
MKS87_13455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKS87_13460	COG0598	Magnesium transport protein CorA
MKS87_13465	COG1253	flavin adenine dinucleotide binding
MKS87_13470	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_13480	COG1393	Belongs to the ArsC family
MKS87_13490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_13500	COG0011	TIGRFAM Protein of
MKS87_13510	COG2866	Carboxypeptidase
MKS87_13515	COG1368	sulfuric ester hydrolase activity
MKS87_13520	COG1940	carbohydrate kinase activity
MKS87_13525	COG4483	Protein conserved in bacteria
MKS87_13530	COG0705	Rhomboid family
MKS87_13530	COG0457	Tetratricopeptide repeat
MKS87_13540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKS87_13550	COG0438	transferase activity, transferring glycosyl groups
MKS87_13565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKS87_13570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MKS87_13575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MKS87_13580	COG0581	inorganic phosphate transmembrane transporter activity
MKS87_13585	COG0573	inorganic phosphate transmembrane transporter activity
MKS87_13590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MKS87_13595	COG0768	penicillin binding
MKS87_13600	COG0477	Major facilitator Superfamily
MKS87_13605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKS87_13610	COG2839	Protein conserved in bacteria
MKS87_13615	COG5521	maltodextrose utilization protein MalA
MKS87_13620	COG1388	LysM domain
MKS87_13625	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MKS87_13630	COG4709	membrane
MKS87_13635	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MKS87_13640	COG0735	belongs to the Fur family
MKS87_13645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKS87_13655	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKS87_13660	COG0513	Belongs to the DEAD box helicase family
MKS87_13670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKS87_13675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKS87_13680	COG2384	SAM-dependent methyltransferase
MKS87_13685	COG2010	Cytochrome c
MKS87_13690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKS87_13695	COG0358	DNA primase activity
MKS87_13700	COG1671	Belongs to the UPF0178 family
MKS87_13705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MKS87_13710	COG0517	IMP dehydrogenase activity
MKS87_13715	COG0751	glycine-tRNA ligase activity
MKS87_13720	COG0752	glycyl-tRNA synthetase alpha subunit
MKS87_13725	COG1381	Involved in DNA repair and RecF pathway recombination
MKS87_13735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKS87_13740	COG0295	cytidine deaminase activity
MKS87_13745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MKS87_13750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKS87_13755	COG1480	7TM receptor with intracellular HD hydrolase
MKS87_13760	COG1702	phosphate starvation-inducible protein PhoH
MKS87_13765	COG0561	phosphatase activity
MKS87_13780	COG4864	UPF0365 protein
MKS87_13785	COG1030	water channel activity
MKS87_13790	COG1610	YqeY-like protein
MKS87_13800	COG1283	sodium-dependent phosphate transmembrane transporter activity
MKS87_13805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKS87_13810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MKS87_13815	COG2264	protein methyltransferase activity
MKS87_13820	COG0484	heat shock protein binding
MKS87_13825	COG0443	Heat shock 70 kDa protein
MKS87_13830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKS87_13835	COG1420	regulation of RNA biosynthetic process
MKS87_13840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MKS87_13845	COG0481	GTPase activity
MKS87_13855	COG0860	N-Acetylmuramoyl-L-alanine amidase
MKS87_13860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MKS87_13865	COG0268	Binds directly to 16S ribosomal RNA
MKS87_13870	COG1466	dna polymerase III delta subunit
MKS87_13885	COG0658	competence protein
MKS87_13885	COG2333	competence protein COMEC
MKS87_13890	COG2131	deaminase
MKS87_13895	COG1596	polysaccharide export
MKS87_13895	COG1555	photosystem II stabilization
MKS87_13900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKS87_13905	COG2226	methyltransferase
MKS87_13910	COG0799	negative regulation of ribosome biogenesis
MKS87_13915	COG1713	HD superfamily hydrolase involved in NAD metabolism
MKS87_13920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKS87_13925	COG1534	Rna-binding protein
MKS87_13930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKS87_13935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKS87_13940	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MKS87_13950	COG2755	lipolytic protein G-D-S-L family
MKS87_13955	COG5632	N-Acetylmuramoyl-L-alanine amidase
MKS87_13955	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_13960	COG0398	Pfam SNARE associated Golgi protein
MKS87_13965	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MKS87_13975	COG3209	COG3209 Rhs family protein
MKS87_13985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MKS87_14010	COG0300	oxidoreductase activity
MKS87_14015	COG1902	pentaerythritol trinitrate reductase activity
MKS87_14020	COG0596	Alpha beta hydrolase
MKS87_14020	COG0508	dehydrogenase complex catalyzes the overall conversion of
MKS87_14025	COG1309	transcriptional regulator
MKS87_14035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MKS87_14045	COG0346	lactoylglutathione lyase activity
MKS87_14050	COG0640	Transcriptional regulator
MKS87_14065	COG0604	alcohol dehydrogenase
MKS87_14075	COG0457	Tetratricopeptide repeat
MKS87_14090	COG5444	nuclease activity
MKS87_14100	COG4282	regulation of fungal-type cell wall biogenesis
MKS87_14175	COG0563	adenylate kinase activity
MKS87_14180	COG2856	Zn peptidase
MKS87_14195	COG0642	Histidine kinase
MKS87_14195	COG5002	protein histidine kinase activity
MKS87_14200	COG0745	RESPONSE REGULATOR receiver
MKS87_14205	COG2311	Membrane
MKS87_14215	COG0454	-acetyltransferase
MKS87_14220	COG2249	NAD(P)H dehydrogenase (quinone) activity
MKS87_14230	COG0730	response to heat
MKS87_14235	COG0425	Belongs to the sulfur carrier protein TusA family
MKS87_14250	COG0425	Belongs to the sulfur carrier protein TusA family
MKS87_14250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKS87_14255	COG2210	Belongs to the sulfur carrier protein TusA family
MKS87_14260	COG1937	Protein conserved in bacteria
MKS87_14270	COG0662	Cupin 2, conserved barrel domain protein
MKS87_14285	COG0789	Transcriptional regulator
MKS87_14285	COG4978	Transcriptional regulator
MKS87_14290	COG2814	Major facilitator Superfamily
MKS87_14295	COG0456	acetyltransferase
MKS87_14300	COG1253	flavin adenine dinucleotide binding
MKS87_14310	COG0697	spore germination
MKS87_14315	COG0583	DNA-binding transcription factor activity
MKS87_14320	COG2072	flavoprotein involved in K transport
MKS87_14325	COG1230	cation diffusion facilitator family transporter
MKS87_14330	COG1942	4-Oxalocrotonate Tautomerase
MKS87_14335	COG0583	DNA-binding transcription factor activity
MKS87_14345	COG1114	Component of the transport system for branched-chain amino acids
MKS87_14350	COG1687	branched-chain amino acid
MKS87_14355	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MKS87_14360	COG1522	sequence-specific DNA binding
MKS87_14370	COG2124	cytochrome p450
MKS87_14385	COG1335	isochorismatase
MKS87_14400	COG2318	DinB family
MKS87_14410	COG2070	2-Nitropropane dioxygenase
MKS87_14415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MKS87_14435	COG3443	Belongs to the bacterial solute-binding protein 9 family
MKS87_14440	COG1595	DNA-templated transcription, initiation
MKS87_14445	COG0667	Aldo Keto reductase
MKS87_14450	COG2851	Citrate transporter
MKS87_14455	COG0583	DNA-binding transcription factor activity
MKS87_14460	COG2828	Protein conserved in bacteria
MKS87_14465	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_14470	COG5566	PFAM Mor transcription activator
MKS87_14475	COG0596	Alpha beta hydrolase
MKS87_14480	COG4991	sh3 domain protein
MKS87_14485	COG4991	sh3 domain protein
MKS87_14495	COG0346	lactoylglutathione lyase activity
MKS87_14505	COG5577	PFAM Coat F domain
MKS87_14510	COG1063	alcohol dehydrogenase
MKS87_14520	COG5577	PFAM Coat F domain
MKS87_14525	COG0789	Transcriptional regulator
MKS87_14535	COG1064	alcohol dehydrogenase
MKS87_14540	COG0693	protein deglycase activity
MKS87_14545	COG1621	beta-fructofuranosidase activity
MKS87_14555	COG3716	PTS system mannose fructose sorbose family IID component
MKS87_14560	COG3715	PTS system
MKS87_14565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_14570	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_14575	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MKS87_14575	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MKS87_14585	COG1113	amino acid transport
MKS87_14590	COG1280	lysine exporter protein (LysE YggA)
MKS87_14595	COG1378	Sugar-specific transcriptional regulator TrmB
MKS87_14600	COG1595	DNA-templated transcription, initiation
MKS87_14610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MKS87_14610	COG2755	lipolytic protein G-D-S-L family
MKS87_14620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKS87_14620	COG2124	cytochrome p450
MKS87_14625	COG1309	transcriptional regulator
MKS87_14630	COG2226	methyltransferase
MKS87_14645	COG2116	formate transmembrane transporter activity
MKS87_14650	COG5609	conserved protein (DUF2294)
MKS87_14655	COG3383	formate dehydrogenase (NAD+) activity
MKS87_14660	COG2427	Protein of unknown function (DUF1641)
MKS87_14670	COG0626	cystathionine gamma-synthase activity
MKS87_14675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MKS87_14680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKS87_14685	COG2226	methyltransferase
MKS87_14700	COG0768	penicillin binding
MKS87_14705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MKS87_14710	COG0572	uridine kinase
MKS87_14715	COG0826	peptidase U32
MKS87_14720	COG0826	peptidase U32
MKS87_14725	COG4122	O-methyltransferase activity
MKS87_14730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKS87_14735	COG3906	Belongs to the UPF0473 family
MKS87_14740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKS87_14745	COG4472	Bacterial protein of unknown function (DUF965)
MKS87_14750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKS87_14755	COG0628	permease
MKS87_14760	COG1126	abc transporter atp-binding protein
MKS87_14765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKS87_14770	COG0765	amino acid transport
MKS87_14775	COG0765	amino acid transport
MKS87_14790	COG3881	PFAM PRC-barrel domain
MKS87_14795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MKS87_14800	COG0457	Tetratricopeptide repeat
MKS87_14805	COG0482	sulfurtransferase activity
MKS87_14810	COG1104	cysteine desulfurase activity
MKS87_14815	COG1959	2 iron, 2 sulfur cluster binding
MKS87_14820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MKS87_14825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MKS87_14835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MKS87_14840	COG0124	histidyl-tRNA synthetase
MKS87_14850	COG0860	N-Acetylmuramoyl-L-alanine amidase
MKS87_14850	COG4991	sh3 domain protein
MKS87_14850	COG3103	Sh3 type 3 domain protein
MKS87_14855	COG1490	D-aminoacyl-tRNA deacylase activity
MKS87_14860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKS87_14865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKS87_14870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MKS87_14870	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MKS87_14875	COG5416	Lipopolysaccharide assembly protein A domain
MKS87_14880	COG0490	domain, Protein
MKS87_14885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKS87_14885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKS87_14895	COG2244	polysaccharide biosynthetic process
MKS87_14900	COG2323	membrane
MKS87_14910	COG1862	Preprotein translocase
MKS87_14915	COG0343	queuine tRNA-ribosyltransferase activity
MKS87_14920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKS87_14930	COG2255	four-way junction helicase activity
MKS87_14935	COG0632	four-way junction helicase activity
MKS87_14945	COG2814	Major facilitator Superfamily
MKS87_14950	COG0673	inositol 2-dehydrogenase activity
MKS87_14955	COG2112	serine threonine protein kinase
MKS87_14975	COG1115	amino acid carrier protein
MKS87_14980	COG0217	transcriptional regulatory protein
MKS87_14990	COG1388	LysM domain
MKS87_14995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MKS87_15000	COG0157	Belongs to the NadC ModD family
MKS87_15005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MKS87_15010	COG1104	cysteine desulfurase activity
MKS87_15015	COG1827	regulation of RNA biosynthetic process
MKS87_15020	COG0077	Prephenate dehydratase
MKS87_15025	COG4492	Belongs to the UPF0735 family
MKS87_15030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKS87_15035	COG3290	protein histidine kinase activity
MKS87_15045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MKS87_15050	COG2868	ribosomal protein
MKS87_15055	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MKS87_15060	COG1994	Peptidase M50
MKS87_15065	COG0739	heme binding
MKS87_15070	COG2894	cell division
MKS87_15075	COG0850	regulation of cytokinetic process
MKS87_15080	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MKS87_15090	COG1077	Cell shape determining protein MreB Mrl
MKS87_15095	COG2003	Belongs to the UPF0758 family
MKS87_15100	COG0424	maF-like protein
MKS87_15110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MKS87_15115	COG0285	dihydrofolate synthase activity
MKS87_15120	COG0525	valine-tRNA ligase activity
MKS87_15130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKS87_15135	COG1388	LysM domain
MKS87_15140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MKS87_15145	COG0113	porphobilinogen synthase activity
MKS87_15150	COG1587	Uroporphyrinogen-III synthase
MKS87_15155	COG0181	hydroxymethylbilane synthase activity
MKS87_15160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MKS87_15165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MKS87_15175	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MKS87_15180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MKS87_15185	COG0470	DNA polymerase III
MKS87_15185	COG1067	ATP-dependent peptidase activity
MKS87_15190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKS87_15195	COG0544	peptidyl-prolyl cis-trans isomerase activity
MKS87_15200	COG0457	Tetratricopeptide repeat
MKS87_15200	COG1477	protein flavinylation
MKS87_15205	COG0066	3-isopropylmalate dehydratase activity
MKS87_15210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKS87_15215	COG0473	3-isopropylmalate dehydrogenase activity
MKS87_15220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKS87_15225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKS87_15230	COG0440	acetolactate synthase activity
MKS87_15235	COG0028	Belongs to the TPP enzyme family
MKS87_15245	COG0454	-acetyltransferase
MKS87_15250	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
MKS87_15260	COG0622	Phosphoesterase
MKS87_15265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKS87_15270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKS87_15275	COG5401	PFAM Sporulation and spore germination
MKS87_15280	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MKS87_15285	COG1846	Transcriptional regulator
MKS87_15290	COG2197	response regulator
MKS87_15295	COG0824	Thioesterase
MKS87_15300	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MKS87_15305	COG1053	succinate dehydrogenase
MKS87_15310	COG2009	succinate dehydrogenase
MKS87_15315	COG1719	4-vinyl reductase, 4VR
MKS87_15320	COG0527	aspartate kinase activity
MKS87_15325	COG0322	excinuclease ABC activity
MKS87_15330	COG3118	belongs to the thioredoxin family
MKS87_15335	COG3534	alpha-L-arabinofuranosidase
MKS87_15340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MKS87_15345	COG2086	electron transfer activity
MKS87_15350	COG1024	Enoyl-CoA hydratase
MKS87_15355	COG1309	transcriptional regulator
MKS87_15360	COG0318	PFAM AMP-dependent synthetase and ligase
MKS87_15365	COG3766	membrane
MKS87_15370	COG1193	negative regulation of DNA recombination
MKS87_15375	COG1796	DNA polymerase
MKS87_15375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MKS87_15380	COG1286	toxin biosynthetic process
MKS87_15385	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKS87_15390	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKS87_15395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKS87_15395	COG0072	phenylalanine-tRNA ligase activity
MKS87_15400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKS87_15410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKS87_15420	COG3835	regulator
MKS87_15425	COG0277	FAD linked oxidase domain protein
MKS87_15430	COG0247	lactate metabolic process
MKS87_15435	COG0346	lactoylglutathione lyase activity
MKS87_15445	COG1966	Carbon starvation protein
MKS87_15450	COG3534	alpha-L-arabinofuranosidase
MKS87_15455	COG0395	ABC-type sugar transport system, permease component
MKS87_15460	COG1175	transmembrane transport
MKS87_15465	COG1653	transport
MKS87_15470	COG0371	Dehydrogenase
MKS87_15475	COG0647	UMP catabolic process
MKS87_15480	COG0235	Class ii aldolase
MKS87_15485	COG1069	ribulokinase activity
MKS87_15490	COG2160	L-arabinose isomerase activity
MKS87_15495	COG3507	Belongs to the glycosyl hydrolase 43 family
MKS87_15500	COG1363	Peptidase, m42
MKS87_15510	COG3326	Membrane
MKS87_15515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKS87_15520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MKS87_15525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKS87_15535	COG1346	cytolysis
MKS87_15540	COG1380	Effector of murein hydrolase LrgA
MKS87_15545	COG3279	Response regulator of the LytR AlgR family
MKS87_15550	COG3275	phosphorelay sensor kinase activity
MKS87_15555	COG1011	Hydrolase
MKS87_15560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKS87_15570	COG0398	Pfam SNARE associated Golgi protein
MKS87_15575	COG1484	DNA-dependent DNA replication
MKS87_15580	COG3611	Membrane attachment protein
MKS87_15585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKS87_15590	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MKS87_15595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MKS87_15600	COG1733	regulation of RNA biosynthetic process
MKS87_15605	COG2814	Major facilitator Superfamily
MKS87_15610	COG0656	L-ascorbic acid biosynthetic process
MKS87_15615	COG0237	dephospho-CoA kinase activity
MKS87_15620	COG1971	Probably functions as a manganese efflux pump
MKS87_15625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MKS87_15630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKS87_15630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKS87_15635	COG5002	protein histidine kinase activity
MKS87_15640	COG0745	RESPONSE REGULATOR receiver
MKS87_15645	COG0039	L-malate dehydrogenase activity
MKS87_15650	COG0538	isocitrate dehydrogenase activity
MKS87_15655	COG0372	Belongs to the citrate synthase family
MKS87_15660	COG2707	UPF0756 membrane protein
MKS87_15665	COG0628	permease
MKS87_15670	COG3030	protein affecting phage T7 exclusion by the F plasmid
MKS87_15675	COG0469	pyruvate kinase activity
MKS87_15680	COG0205	6-phosphofructokinase activity
MKS87_15685	COG0825	malonyl-CoA metabolic process
MKS87_15690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKS87_15695	COG0281	malic enzyme
MKS87_15700	COG0587	DNA-directed DNA polymerase activity
MKS87_15720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MKS87_15730	COG4109	DRTGG domain
MKS87_15735	COG0730	response to heat
MKS87_15740	COG1473	amidohydrolase
MKS87_15745	COG0196	riboflavin kinase activity
MKS87_15750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKS87_15755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MKS87_15760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKS87_15765	COG1126	abc transporter atp-binding protein
MKS87_15770	COG0765	amino acid transport
MKS87_15775	COG0765	amino acid transport
MKS87_15780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKS87_15785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKS87_15790	COG0454	-acetyltransferase
MKS87_15795	COG0583	DNA-binding transcription factor activity
MKS87_15800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MKS87_15805	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_15810	COG0165	Argininosuccinate lyase
MKS87_15815	COG0137	argininosuccinate synthase activity
MKS87_15820	COG0521	Mo-molybdopterin cofactor biosynthetic process
MKS87_15825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKS87_15835	COG0827	DNA restriction-modification system
MKS87_15840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKS87_15845	COG3874	Sporulation protein YtfJ
MKS87_15855	COG1714	RDD family
MKS87_15860	COG0616	signal peptide processing
MKS87_15865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKS87_15870	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MKS87_15875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKS87_15885	COG0301	tRNA thio-modification
MKS87_15890	COG1104	cysteine desulfurase activity
MKS87_15895	COG1114	Component of the transport system for branched-chain amino acids
MKS87_15900	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKS87_15905	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MKS87_15910	COG1309	transcriptional regulator
MKS87_15915	COG1956	GAF domain-containing protein
MKS87_15920	COG2199	diguanylate cyclase activity
MKS87_15920	COG2203	Gaf domain
MKS87_15925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKS87_15930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKS87_15935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MKS87_15940	COG0454	-acetyltransferase
MKS87_15945	COG0517	IMP dehydrogenase activity
MKS87_15950	COG0123	including yeast histone deacetylase and acetoin utilization protein
MKS87_15955	COG1360	Flagellar Motor Protein
MKS87_15960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MKS87_15965	COG1609	Transcriptional regulator
MKS87_15970	COG1605	Chorismate mutase
MKS87_15970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MKS87_15975	COG3118	belongs to the thioredoxin family
MKS87_15980	COG4980	gas vesicle protein
MKS87_15985	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKS87_15990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MKS87_15995	COG1674	ftsk spoiiie
MKS87_16000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKS87_16005	COG4848	Belongs to the UPF0354 family
MKS87_16010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_16025	COG1363	Peptidase, m42
MKS87_16030	COG5584	Small secreted protein
MKS87_16035	COG0281	malic enzyme
MKS87_16040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_16045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MKS87_16055	COG0510	thiamine kinase activity
MKS87_16060	COG1523	belongs to the glycosyl hydrolase 13 family
MKS87_16065	COG1597	lipid kinase activity
MKS87_16075	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MKS87_16080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MKS87_16085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MKS87_16090	COG2252	PERMEase
MKS87_16095	COG4473	ABC transporter
MKS87_16100	COG1131	(ABC) transporter
MKS87_16105	COG1349	DNA-binding transcription factor activity
MKS87_16110	COG1187	pseudouridine synthase activity
MKS87_16115	COG2244	polysaccharide biosynthetic process
MKS87_16120	COG2081	HI0933 family
MKS87_16125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MKS87_16135	COG5578	integral membrane protein
MKS87_16140	COG0673	inositol 2-dehydrogenase activity
MKS87_16145	COG1653	transport
MKS87_16150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MKS87_16155	COG4209	transmembrane transport
MKS87_16160	COG2207	Transcriptional regulator
MKS87_16165	COG1653	transport
MKS87_16170	COG0395	ABC-type sugar transport system, permease component
MKS87_16175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKS87_16180	COG2124	cytochrome p450
MKS87_16185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MKS87_16195	COG0156	8-amino-7-oxononanoate synthase activity
MKS87_16200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MKS87_16205	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MKS87_16210	COG1073	alpha beta
MKS87_16215	COG1609	Transcriptional regulator
MKS87_16220	COG1653	transport
MKS87_16225	COG1175	transmembrane transport
MKS87_16230	COG0395	ABC-type sugar transport system, permease component
MKS87_16235	COG1486	melibiose metabolic process
MKS87_16240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKS87_16245	COG0495	leucyl-tRNA aminoacylation
MKS87_16255	COG1366	Belongs to the anti-sigma-factor antagonist family
MKS87_16255	COG2202	Pas domain
MKS87_16260	COG2814	Major facilitator Superfamily
MKS87_16265	COG2433	Pfam Transposase IS66
MKS87_16270	COG0577	efflux transmembrane transporter activity
MKS87_16275	COG1136	(ABC) transporter
MKS87_16280	COG2205	protein histidine kinase activity
MKS87_16285	COG0745	RESPONSE REGULATOR receiver
MKS87_16290	COG0577	efflux transmembrane transporter activity
MKS87_16295	COG1136	(ABC) transporter
MKS87_16310	COG1131	(ABC) transporter
MKS87_16315	COG1725	Transcriptional regulator
MKS87_16330	COG1242	4 iron, 4 sulfur cluster binding
MKS87_16335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MKS87_16345	COG2267	carboxylic ester hydrolase activity
MKS87_16350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MKS87_16355	COG1113	amino acid transport
MKS87_16360	COG0367	asparagine synthase
MKS87_16365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKS87_16370	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MKS87_16380	COG1506	peptidase
MKS87_16385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MKS87_16390	COG1116	anion transmembrane transporter activity
MKS87_16395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MKS87_16400	COG0494	nUDIX hydrolase
MKS87_16405	COG4824	toxin secretion phage lysis holin
MKS87_16410	COG0783	Belongs to the Dps family
MKS87_16425	COG1854	S-ribosylhomocysteine lyase activity
MKS87_16430	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MKS87_16435	COG0288	reversible hydration of carbon dioxide
MKS87_16440	COG0254	rRNA binding
MKS87_16445	COG1271	oxidase subunit
MKS87_16450	COG1294	oxidase, subunit
MKS87_16460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKS87_16465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MKS87_16465	COG1321	iron dependent repressor
MKS87_16470	COG1121	(ABC) transporter
MKS87_16475	COG0803	Belongs to the bacterial solute-binding protein 9 family
MKS87_16480	COG4948	Mandelate Racemase Muconate Lactonizing
MKS87_16485	COG0318	PFAM AMP-dependent synthetase and ligase
MKS87_16490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MKS87_16495	COG0596	Alpha beta hydrolase
MKS87_16500	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MKS87_16505	COG1169	isochorismate synthase
MKS87_16510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MKS87_16515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MKS87_16520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKS87_16525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MKS87_16530	COG0438	transferase activity, transferring glycosyl groups
MKS87_16540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKS87_16545	COG0438	transferase activity, transferring glycosyl groups
MKS87_16550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKS87_16555	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MKS87_16560	COG0058	SHG alpha-glucan phosphorylase activity
MKS87_16565	COG0297	glycogen (starch) synthase activity
MKS87_16570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKS87_16575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKS87_16580	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKS87_16705	COG3859	Proton-coupled thiamine transporter YuaJ
MKS87_16710	COG1247	-acetyltransferase
MKS87_16715	COG2268	Band 7 protein
MKS87_16720	COG1585	Membrane protein implicated in regulation of membrane protease activity
MKS87_16725	COG2318	DinB family
MKS87_16735	COG1454	alcohol dehydrogenase
MKS87_16740	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_16745	COG1510	regulation of RNA biosynthetic process
MKS87_16755	COG0569	domain protein
MKS87_16760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MKS87_16765	COG4682	membrane
MKS87_16770	COG1705	Flagellar rod assembly protein muramidase FlgJ
MKS87_16775	COG0477	Major facilitator Superfamily
MKS87_16780	COG5553	Cysteine dioxygenase type I
MKS87_16790	COG1968	undecaprenyl-diphosphatase activity
MKS87_16795	COG0628	permease
MKS87_16800	COG0673	inositol 2-dehydrogenase activity
MKS87_16805	COG4806	L-rhamnose isomerase
MKS87_16810	COG3254	rhamnose metabolic process
MKS87_16815	COG1070	Carbohydrate kinase
MKS87_16820	COG1349	DNA-binding transcription factor activity
MKS87_16825	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_16825	COG3347	Dehydrogenase
MKS87_16830	COG0840	transmembrane signaling receptor activity
MKS87_16835	COG0840	transmembrane signaling receptor activity
MKS87_16840	COG0840	transmembrane signaling receptor activity
MKS87_16845	COG0840	transmembrane signaling receptor activity
MKS87_16865	COG0432	Pfam Uncharacterised protein family UPF0047
MKS87_16875	COG0366	Alpha amylase catalytic
MKS87_16880	COG1253	flavin adenine dinucleotide binding
MKS87_16885	COG2738	Putative neutral zinc metallopeptidase
MKS87_16900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MKS87_16915	COG0166	Belongs to the GPI family
MKS87_16920	COG1979	alcohol dehydrogenase
MKS87_16925	COG1979	alcohol dehydrogenase
MKS87_16930	COG2155	Conserved Protein
MKS87_16935	COG1098	S1 RNA binding domain
MKS87_16940	COG0436	Aminotransferase
MKS87_16945	COG1522	sequence-specific DNA binding
MKS87_16950	COG2267	carboxylic ester hydrolase activity
MKS87_16960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MKS87_16965	COG2205	protein histidine kinase activity
MKS87_16975	COG5018	Exonuclease
MKS87_16985	COG2814	Major facilitator Superfamily
MKS87_16990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKS87_16995	COG3011	Protein conserved in bacteria
MKS87_17005	COG3290	protein histidine kinase activity
MKS87_17010	COG4565	transcriptional regulatory protein
MKS87_17015	COG1744	ABC transporter substrate-binding protein PnrA-like
MKS87_17020	COG3845	ABC transporter
MKS87_17025	COG4603	Belongs to the binding-protein-dependent transport system permease family
MKS87_17030	COG1079	Belongs to the binding-protein-dependent transport system permease family
MKS87_17035	COG3493	citrate carrier protein
MKS87_17045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MKS87_17045	COG2111	Na H antiporter
MKS87_17050	COG2111	Na H antiporter
MKS87_17055	COG1006	Multisubunit Na H antiporter MnhC subunit
MKS87_17060	COG0651	ATP synthesis coupled electron transport
MKS87_17065	COG1863	multisubunit Na H antiporter MnhE subunit
MKS87_17070	COG2212	antiporter activity
MKS87_17075	COG1320	monovalent cation:proton antiporter activity
MKS87_17080	COG2050	protein possibly involved in aromatic compounds catabolism
MKS87_17085	COG2197	response regulator
MKS87_17100	COG0142	geranyltranstransferase activity
MKS87_17120	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MKS87_17125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKS87_17130	COG1335	isochorismatase
MKS87_17135	COG5506	Protein of unknown function (DUF1694)
MKS87_17150	COG0628	permease
MKS87_17165	COG1418	mRNA catabolic process
MKS87_17170	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_17180	COG1511	domain protein
MKS87_17185	COG0433	COG0433 Predicted ATPase
MKS87_17185	COG1674	ftsk spoiiie
MKS87_17190	COG4499	WXG100 protein secretion system (Wss), protein YukC
MKS87_17195	COG5417	Belongs to the EsaB family
MKS87_17200	COG4842	Belongs to the WXG100 family
MKS87_17205	COG2508	Transcriptional regulator
MKS87_17205	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MKS87_17210	COG0686	Belongs to the AlaDH PNT family
MKS87_17215	COG5634	Uncharacterized conserved protein (DUF2278)
MKS87_17220	COG3251	PFAM MbtH domain protein
MKS87_17225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_17230	COG1535	isochorismatase
MKS87_17230	COG3433	isochorismatase activity
MKS87_17235	COG1021	2,3-dihydroxybenzoate-AMP ligase
MKS87_17240	COG1169	isochorismate synthase
MKS87_17245	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_17250	COG2819	hydrolase of the alpha beta superfamily
MKS87_17255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKS87_17260	COG1268	BioY protein
MKS87_17265	COG2056	Na+-H+ antiporter family
MKS87_17270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKS87_17275	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MKS87_17280	COG3584	3D domain protein
MKS87_17295	COG1252	NADH dehydrogenase
MKS87_17300	COG0492	ferredoxin-NADP+ reductase activity
MKS87_17310	COG0516	GMP reductase activity
MKS87_17315	COG2808	Putative FMN-binding domain
MKS87_17320	COG0456	acetyltransferase
MKS87_17325	COG0316	Belongs to the HesB IscA family
MKS87_17330	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKS87_17335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKS87_17340	COG4844	belongs to the
MKS87_17345	COG1252	NADH dehydrogenase
MKS87_17350	COG4837	Protein of unknown function (DUF1462)
MKS87_17355	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MKS87_17360	COG0823	Involved in the tonB-independent uptake of proteins
MKS87_17360	COG4946	Tricorn protease homolog
MKS87_17360	COG1506	peptidase
MKS87_17365	COG0083	homoserine kinase activity
MKS87_17370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKS87_17375	COG0460	homoserine dehydrogenase
MKS87_17380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKS87_17385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MKS87_17390	COG0647	UMP catabolic process
MKS87_17395	COG2445	Protein of unknown function DUF86
MKS87_17400	COG4470	Protein conserved in bacteria
MKS87_17410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MKS87_17415	COG0739	heme binding
MKS87_17425	COG3377	Domain of unknown function (DUF1805)
MKS87_17430	COG0737	Belongs to the 5'-nucleotidase family
MKS87_17435	COG0730	response to heat
MKS87_17440	COG1801	Protein of unknown function DUF72
MKS87_17450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MKS87_17455	COG2508	Transcriptional regulator
MKS87_17460	COG2233	PERMEase
MKS87_17465	COG2233	PERMEase
MKS87_17470	COG3195	allantoin biosynthetic process
MKS87_17470	COG3648	Uricase
MKS87_17475	COG2351	hydroxyisourate hydrolase activity
MKS87_17485	COG2080	2 iron, 2 sulfur cluster binding
MKS87_17490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MKS87_17495	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MKS87_17500	COG2068	MobA-Related Protein
MKS87_17505	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MKS87_17510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MKS87_17515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MKS87_17525	COG2356	endonuclease I
MKS87_17530	COG3842	ATPase activity
MKS87_17535	COG2188	Transcriptional regulator
MKS87_17540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKS87_17545	COG0395	ABC-type sugar transport system, permease component
MKS87_17550	COG1175	transmembrane transport
MKS87_17555	COG1653	transport
MKS87_17560	COG2222	sugar isomerase
MKS87_17565	COG0322	excinuclease ABC activity
MKS87_17570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MKS87_17585	COG0719	Fe-S assembly protein
MKS87_17590	COG0822	iron-sulfur transferase activity
MKS87_17595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKS87_17600	COG0719	Fe-S assembly protein
MKS87_17605	COG0396	ATPase activity
MKS87_17615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKS87_17620	COG1464	Belongs to the NlpA lipoprotein family
MKS87_17625	COG2011	ABC-type metal ion transport system permease component
MKS87_17630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKS87_17640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MKS87_17645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKS87_17655	COG0509	glycine decarboxylation via glycine cleavage system
MKS87_17660	COG1393	Belongs to the ArsC family
MKS87_17665	COG1960	acyl-CoA dehydrogenase activity
MKS87_17670	COG0183	Belongs to the thiolase family
MKS87_17675	COG1024	Enoyl-CoA hydratase
MKS87_17675	COG1250	3-hydroxyacyl-CoA dehydrogenase
MKS87_17685	COG0506	proline dehydrogenase activity
MKS87_17695	COG5577	PFAM Coat F domain
MKS87_17700	COG1846	Transcriptional regulator
MKS87_17705	COG0477	Major facilitator Superfamily
MKS87_17710	COG1942	4-Oxalocrotonate Tautomerase
MKS87_17715	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_17720	COG0583	DNA-binding transcription factor activity
MKS87_17730	COG1120	ATPase activity
MKS87_17745	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_17750	COG0783	Belongs to the Dps family
MKS87_17755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKS87_17760	COG0745	RESPONSE REGULATOR receiver
MKS87_17765	COG2205	protein histidine kinase activity
MKS87_17765	COG2770	Histidine kinase
MKS87_17775	COG1309	transcriptional regulator
MKS87_17780	COG0114	fumarate hydratase activity
MKS87_17790	COG0697	spore germination
MKS87_17795	COG0814	amino acid
MKS87_17805	COG2197	response regulator
MKS87_17810	COG4585	Histidine kinase
MKS87_17815	COG4758	membrane
MKS87_17820	COG3595	metallopeptidase activity
MKS87_17825	COG1842	Phage shock protein A
MKS87_17830	COG4758	membrane
MKS87_17835	COG2814	Major facilitator Superfamily
MKS87_17840	COG2096	Adenosyltransferase
MKS87_17845	COG1120	ATPase activity
MKS87_17850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_17855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKS87_17860	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_17865	COG3386	PFAM SMP-30 Gluconolaconase
MKS87_17870	COG2205	protein histidine kinase activity
MKS87_17875	COG0745	RESPONSE REGULATOR receiver
MKS87_17885	COG1191	sigma factor activity
MKS87_17895	COG2140	Oxalate decarboxylase
MKS87_17905	COG0577	efflux transmembrane transporter activity
MKS87_17910	COG1136	(ABC) transporter
MKS87_17915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKS87_17920	COG1120	ATPase activity
MKS87_17925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_17930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKS87_17935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKS87_17940	COG0531	amino acid
MKS87_17950	COG1988	membrane-bound metal-dependent
MKS87_17955	COG1368	sulfuric ester hydrolase activity
MKS87_17960	COG1910	domain protein
MKS87_17965	COG0725	ABC transporter, periplasmic molybdate-binding protein
MKS87_17970	COG4149	molybdate abc transporter
MKS87_17975	COG0656	L-ascorbic acid biosynthetic process
MKS87_17985	COG0025	NhaP-type Na H and K H
MKS87_17990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKS87_17995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKS87_18000	COG3973	AAA domain
MKS87_18005	COG2860	membrane
MKS87_18010	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MKS87_18015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MKS87_18020	COG2217	Heavy metal translocating P-type atpase
MKS87_18025	COG2217	Heavy metal translocating P-type atpase
MKS87_18030	COG2608	mercury ion transmembrane transporter activity
MKS87_18035	COG1937	Protein conserved in bacteria
MKS87_18040	COG0673	inositol 2-dehydrogenase activity
MKS87_18045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKS87_18050	COG1289	transmembrane transporter activity
MKS87_18060	COG2076	Multidrug Resistance protein
MKS87_18065	COG1309	transcriptional regulator
MKS87_18070	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_18080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MKS87_18085	COG0557	exoribonuclease II activity
MKS87_18090	COG1647	Serine aminopeptidase, S33
MKS87_18095	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MKS87_18100	COG0596	Alpha beta hydrolase
MKS87_18105	COG1476	TRANSCRIPTIONal
MKS87_18110	COG1396	sequence-specific DNA binding
MKS87_18115	COG1396	sequence-specific DNA binding
MKS87_18120	COG1733	regulation of RNA biosynthetic process
MKS87_18125	COG0840	transmembrane signaling receptor activity
MKS87_18130	COG1174	glycine betaine transport
MKS87_18135	COG1732	Glycine betaine
MKS87_18140	COG1174	glycine betaine transport
MKS87_18145	COG1125	glycine betaine transport
MKS87_18145	COG0517	IMP dehydrogenase activity
MKS87_18150	COG1510	regulation of RNA biosynthetic process
MKS87_18155	COG1174	glycine betaine transport
MKS87_18160	COG1732	Glycine betaine
MKS87_18165	COG1174	glycine betaine transport
MKS87_18170	COG0517	IMP dehydrogenase activity
MKS87_18170	COG1125	glycine betaine transport
MKS87_18175	COG1510	regulation of RNA biosynthetic process
MKS87_18180	COG2095	MarC family integral membrane protein
MKS87_18190	COG3064	Membrane
MKS87_18195	COG4640	response to antibiotic
MKS87_18200	COG0456	acetyltransferase
MKS87_18205	COG0148	phosphopyruvate hydratase activity
MKS87_18210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKS87_18215	COG0149	triose-phosphate isomerase activity
MKS87_18220	COG0126	phosphoglycerate kinase activity
MKS87_18225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MKS87_18230	COG2390	Transcriptional regulator
MKS87_18235	COG2814	Major facilitator Superfamily
MKS87_18240	COG1609	Transcriptional regulator
MKS87_18245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKS87_18250	COG0583	DNA-binding transcription factor activity
MKS87_18255	COG0697	spore germination
MKS87_18260	COG1113	amino acid transport
MKS87_18265	COG3858	chitin binding
MKS87_18270	COG1556	Lactate utilization protein
MKS87_18275	COG1139	Iron-sulfur cluster binding protein
MKS87_18280	COG0247	lactate metabolic process
MKS87_18285	COG2197	response regulator
MKS87_18290	COG4585	Histidine kinase
MKS87_18295	COG0842	Transport permease protein
MKS87_18300	COG1131	(ABC) transporter
MKS87_18305	COG0596	Alpha beta hydrolase
MKS87_18310	COG2208	phosphoserine phosphatase activity
MKS87_18315	COG3867	Arabinogalactan endo-beta-1,4-galactanase
MKS87_18320	COG1874	Beta-galactosidase
MKS87_18325	COG3833	ABC-type maltose transport systems, permease component
MKS87_18330	COG1175	transmembrane transport
MKS87_18335	COG2182	Extracellular solute-binding protein
MKS87_18340	COG1609	Transcriptional regulator
MKS87_18345	COG2186	Transcriptional regulator
MKS87_18350	COG1620	l-lactate permease
MKS87_18355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MKS87_18365	COG5039	Polysaccharide pyruvyl transferase
MKS87_18370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MKS87_18375	COG0110	maltose O-acetyltransferase activity
MKS87_18380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MKS87_18385	COG2244	polysaccharide biosynthetic process
MKS87_18390	COG1216	Glycosyl transferase, family 2
MKS87_18395	COG5039	Polysaccharide pyruvyl transferase
MKS87_18400	COG1216	Glycosyl transferase, family 2
MKS87_18410	COG0438	transferase activity, transferring glycosyl groups
MKS87_18415	COG1215	transferase activity, transferring glycosyl groups
MKS87_18420	COG0438	transferase activity, transferring glycosyl groups
MKS87_18430	COG0489	protein tyrosine kinase activity
MKS87_18435	COG3944	biosynthesis protein
MKS87_18440	COG1396	sequence-specific DNA binding
MKS87_18445	COG2272	Belongs to the type-B carboxylesterase lipase family
MKS87_18455	COG3479	Phenolic acid decarboxylase
MKS87_18465	COG1794	racemase activity, acting on amino acids and derivatives
MKS87_18470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MKS87_18475	COG1621	beta-fructofuranosidase activity
MKS87_18480	COG1621	beta-fructofuranosidase activity
MKS87_18485	COG0531	amino acid
MKS87_18490	COG1309	transcriptional regulator
MKS87_18495	COG2076	Multidrug Resistance protein
MKS87_18500	COG2076	Multidrug Resistance protein
MKS87_18510	COG0277	FAD linked oxidase domain protein
MKS87_18515	COG3621	Patatin-like phospholipase
MKS87_18525	COG0740	serine-type endopeptidase activity
MKS87_18530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MKS87_18535	COG0366	Alpha amylase catalytic
MKS87_18540	COG1554	hydrolase, family 65, central catalytic
MKS87_18545	COG5521	maltodextrose utilization protein MalA
MKS87_18550	COG3833	ABC-type maltose transport systems, permease component
MKS87_18555	COG1175	transmembrane transport
MKS87_18560	COG2182	Extracellular solute-binding protein
MKS87_18565	COG0366	Alpha amylase catalytic
MKS87_18570	COG1609	Transcriptional regulator
MKS87_18575	COG1611	Belongs to the LOG family
MKS87_18580	COG1694	Mazg nucleotide pyrophosphohydrolase
MKS87_18585	COG0659	secondary active sulfate transmembrane transporter activity
MKS87_18590	COG0288	reversible hydration of carbon dioxide
MKS87_18595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKS87_18600	COG0577	efflux transmembrane transporter activity
MKS87_18605	COG1136	(ABC) transporter
MKS87_18610	COG5002	protein histidine kinase activity
MKS87_18615	COG0745	RESPONSE REGULATOR receiver
MKS87_18625	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MKS87_18630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_18635	COG1481	regulation of sporulation
MKS87_18640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MKS87_18645	COG1660	Displays ATPase and GTPase activities
MKS87_18650	COG1051	belongs to the nudix hydrolase family
MKS87_18655	COG0492	ferredoxin-NADP+ reductase activity
MKS87_18660	COG3883	PFAM NLP P60 protein
MKS87_18660	COG0791	NLP P60 protein
MKS87_18665	COG0457	Tetratricopeptide repeat
MKS87_18670	COG1132	(ABC) transporter
MKS87_18690	COG0140	phosphoribosyl-ATP diphosphatase activity
MKS87_18690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MKS87_18695	COG0107	imidazoleglycerol-phosphate synthase activity
MKS87_18700	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKS87_18705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKS87_18710	COG0131	Imidazoleglycerol-phosphate dehydratase
MKS87_18715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKS87_18720	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MKS87_18725	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKS87_18730	COG4990	cell redox homeostasis
MKS87_18735	COG5297	Belongs to the glycosyl hydrolase family 6
MKS87_18740	COG0110	maltose O-acetyltransferase activity
MKS87_18745	COG0546	phosphoglycolate phosphatase activity
MKS87_18750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MKS87_18755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKS87_18760	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKS87_18765	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKS87_18770	COG0363	glucosamine-6-phosphate deaminase activity
MKS87_18775	COG2188	Transcriptional regulator
MKS87_18780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MKS87_18785	COG1846	Transcriptional regulator
MKS87_18790	COG2124	cytochrome p450
MKS87_18800	COG1846	Transcriptional regulator
MKS87_18805	COG2814	Major facilitator Superfamily
MKS87_18810	COG1950	PFAM Membrane protein of
MKS87_18815	COG1983	PspC domain protein
MKS87_18820	COG3595	metallopeptidase activity
MKS87_18835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKS87_18840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MKS87_18850	COG4897	Protein conserved in bacteria
MKS87_18855	COG3848	Pyruvate phosphate dikinase
MKS87_18855	COG0574	Belongs to the PEP-utilizing enzyme family
MKS87_18860	COG1309	transcriptional regulator
MKS87_18865	COG2814	Major facilitator Superfamily
MKS87_18870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKS87_18880	COG3409	Peptidoglycan-binding domain 1 protein
MKS87_18880	COG0793	Belongs to the peptidase S41A family
MKS87_18885	COG2177	Part of the ABC transporter FtsEX involved in
MKS87_18890	COG2884	Cell division ATP-binding protein ftsE
MKS87_18895	COG2010	Cytochrome c
MKS87_18900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKS87_18910	COG0653	protein targeting
MKS87_18915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKS87_18930	COG1516	flagellar protein fliS
MKS87_18935	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKS87_18940	COG1334	flagellar protein FlaG
MKS87_18945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKS87_18950	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MKS87_18955	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MKS87_18965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKS87_18970	COG4786	Flagellar basal body rod
MKS87_18970	COG1256	bacterial-type flagellum assembly
MKS87_18975	COG3418	PFAM FlgN family protein
MKS87_18980	COG2747	anti-sigma28 factor FlgM
MKS87_18990	COG1040	competence protein
MKS87_19000	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKS87_19005	COG1307	EDD domain protein, DegV family
MKS87_19010	COG2197	response regulator
MKS87_19015	COG4585	Histidine kinase
MKS87_19020	COG1739	Uncharacterized protein family UPF0029
MKS87_19025	COG1316	TRANSCRIPTIONal
MKS87_19030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKS87_19035	COG0438	transferase activity, transferring glycosyl groups
MKS87_19040	COG1215	transferase activity, transferring glycosyl groups
MKS87_19045	COG3206	protein involved in exopolysaccharide biosynthesis
MKS87_19050	COG3307	-O-antigen
MKS87_19055	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKS87_19060	COG0438	transferase activity, transferring glycosyl groups
MKS87_19060	COG0297	glycogen (starch) synthase activity
MKS87_19065	COG2244	polysaccharide biosynthetic process
MKS87_19080	COG0860	N-Acetylmuramoyl-L-alanine amidase
MKS87_19080	COG2247	cell wall binding repeat
MKS87_19085	COG2385	sporulation resulting in formation of a cellular spore
MKS87_19085	COG2247	cell wall binding repeat
MKS87_19095	COG1316	TRANSCRIPTIONal
MKS87_19100	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MKS87_19120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MKS87_19125	COG1134	teichoic acid transport
MKS87_19130	COG1682	transport, permease protein
MKS87_19145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKS87_19145	COG1215	transferase activity, transferring glycosyl groups
MKS87_19150	COG0463	Glycosyl transferase, family 2
MKS87_19195	COG4193	domain, Protein
MKS87_19200	COG1482	cell wall glycoprotein biosynthetic process
MKS87_19205	COG0697	spore germination
MKS87_19210	COG0814	amino acid
MKS87_19220	COG2814	Major facilitator Superfamily
MKS87_19225	COG1316	TRANSCRIPTIONal
MKS87_19230	COG0561	phosphatase activity
MKS87_19235	COG0791	NLP P60 protein
MKS87_19245	COG2843	Capsule synthesis protein
MKS87_19255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKS87_19260	COG1609	Transcriptional regulator
MKS87_19265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKS87_19270	COG1869	D-ribose catabolic process
MKS87_19275	COG1129	ABC transporter
MKS87_19280	COG1172	Belongs to the binding-protein-dependent transport system permease family
MKS87_19285	COG1879	ABC-type sugar transport system periplasmic component
MKS87_19290	COG3103	Sh3 type 3 domain protein
MKS87_19300	COG2249	NAD(P)H dehydrogenase (quinone) activity
MKS87_19305	COG3527	Alpha-acetolactate decarboxylase
MKS87_19310	COG0028	Belongs to the TPP enzyme family
MKS87_19315	COG0583	DNA-binding transcription factor activity
MKS87_19320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKS87_19335	COG5337	Spore coat protein CotH
MKS87_19345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKS87_19355	COG0405	Gamma-glutamyltransferase
MKS87_19360	COG1522	sequence-specific DNA binding
MKS87_19365	COG2059	Chromate
MKS87_19370	COG2059	Chromate
MKS87_19380	COG0655	NAD(P)H dehydrogenase (quinone) activity
MKS87_19385	COG0583	DNA-binding transcription factor activity
MKS87_19400	COG5444	nuclease activity
MKS87_19420	COG3878	Protein conserved in bacteria
MKS87_19425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKS87_19430	COG4464	protein tyrosine phosphatase activity
MKS87_19435	COG0489	protein tyrosine kinase activity
MKS87_19440	COG3944	biosynthesis protein
MKS87_19450	COG4715	Zinc finger, swim domain protein
MKS87_19455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MKS87_19460	COG0561	phosphatase activity
MKS87_19465	COG1349	DNA-binding transcription factor activity
MKS87_19470	COG0629	single-stranded DNA binding
MKS87_19485	COG3764	Sortase (surface protein transpeptidase)
MKS87_19495	COG3279	Response regulator of the LytR AlgR family
MKS87_19505	COG0745	RESPONSE REGULATOR receiver
MKS87_19505	COG2972	Histidine kinase
MKS87_19510	COG1970	mechanosensitive ion channel activity
MKS87_19515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MKS87_19520	COG0457	Tetratricopeptide repeat
MKS87_19525	COG4786	Flagellar basal body rod
MKS87_19530	COG4786	Flagellar basal body rod
MKS87_19535	COG1077	Cell shape determining protein MreB Mrl
MKS87_19540	COG1609	Transcriptional regulator
MKS87_19550	COG1846	Transcriptional regulator
MKS87_19555	COG2814	Major facilitator Superfamily
MKS87_19560	COG3420	alginic acid biosynthetic process
MKS87_19565	COG1953	Uracil, thiamine, allantoin
MKS87_19570	COG0477	Major facilitator Superfamily
MKS87_19575	COG1335	isochorismatase
MKS87_19585	COG0004	ammonium transporteR
MKS87_19590	COG0347	Belongs to the P(II) protein family
MKS87_19595	COG0671	phosphoesterase, PA-phosphatase related
MKS87_19605	COG0739	heme binding
MKS87_19610	COG1247	-acetyltransferase
MKS87_19630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKS87_19635	COG0789	Transcriptional regulator
MKS87_19645	COG2910	NAD(P)H-binding
MKS87_19650	COG1959	2 iron, 2 sulfur cluster binding
MKS87_19655	COG0804	urea catabolic process
MKS87_19660	COG0832	Belongs to the urease beta subunit family
MKS87_19665	COG0831	urea catabolic process
MKS87_19680	COG3237	CsbD-like
MKS87_19685	COG1994	Peptidase M50
MKS87_19690	COG0457	Tetratricopeptide repeat
MKS87_19695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MKS87_19700	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MKS87_19710	COG2304	oxidoreductase activity
MKS87_19720	COG2304	oxidoreductase activity
MKS87_19725	COG2385	sporulation resulting in formation of a cellular spore
MKS87_19730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKS87_19740	COG4836	Membrane
MKS87_19750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MKS87_19755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKS87_19760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKS87_19765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKS87_19770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKS87_19775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKS87_19785	COG0356	it plays a direct role in the translocation of protons across the membrane
MKS87_19795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKS87_19800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKS87_19805	COG4475	Protein of unknown function (DUF436)
MKS87_19810	COG0698	ribose 5-phosphate isomerase
MKS87_19815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKS87_19820	COG1971	Probably functions as a manganese efflux pump
MKS87_19825	COG0009	L-threonylcarbamoyladenylate synthase
MKS87_19830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MKS87_19850	COG2890	protein-(glutamine-N5) methyltransferase activity
MKS87_19855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKS87_19860	COG0346	lactoylglutathione lyase activity
MKS87_19865	COG0789	Transcriptional regulator
MKS87_19870	COG0679	Auxin Efflux Carrier
MKS87_19875	COG0281	malic enzyme
MKS87_19880	COG1435	thymidine kinase activity
MKS87_19890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKS87_19900	COG1494	fructose-1,6-bisphosphatase
MKS87_19905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKS87_19910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKS87_19915	COG0191	fructose-bisphosphate aldolase activity
MKS87_19920	COG2204	response regulator
MKS87_19925	COG4821	SIS domain
MKS87_19930	COG0504	CTP synthase activity
MKS87_19935	COG3343	RNA polymerase activity
MKS87_19940	COG1960	acyl-CoA dehydrogenase activity
MKS87_19945	COG0247	lactate metabolic process
MKS87_19945	COG2181	nitrate reductase activity
MKS87_19950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKS87_19955	COG4294	response to UV
MKS87_19965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKS87_19970	COG1132	(ABC) transporter
MKS87_19975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKS87_19985	COG2181	nitrate reductase activity
MKS87_19990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MKS87_19995	COG1140	nitrate reductase beta subunit
MKS87_20000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKS87_20005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MKS87_20015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MKS87_20020	COG2223	nitrite transmembrane transporter activity
MKS87_20025	COG0018	arginyl-trna synthetase
MKS87_20030	COG4506	Protein conserved in bacteria
MKS87_20045	COG0535	radical SAM domain protein
MKS87_20055	COG1131	(ABC) transporter
MKS87_20060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MKS87_20065	COG0612	Peptidase, M16
MKS87_20070	COG0612	Peptidase, M16
MKS87_20080	COG3391	amine dehydrogenase activity
MKS87_20085	COG3391	amine dehydrogenase activity
MKS87_20090	COG0457	Tetratricopeptide repeat
MKS87_20120	COG1131	(ABC) transporter
MKS87_20130	COG0010	Belongs to the arginase family
MKS87_20135	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MKS87_20140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MKS87_20150	COG1994	Peptidase M50
MKS87_20155	COG1942	4-Oxalocrotonate Tautomerase
MKS87_20160	COG1846	Transcriptional regulator
MKS87_20165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKS87_20170	COG0477	Major facilitator Superfamily
MKS87_20175	COG1959	2 iron, 2 sulfur cluster binding
MKS87_20180	COG3465	dGTPase activity
MKS87_20185	COG1078	dGTPase activity
MKS87_20190	COG4844	belongs to the
MKS87_20200	COG0697	spore germination
MKS87_20205	COG0095	Lipoate-protein ligase
MKS87_20210	COG0583	DNA-binding transcription factor activity
MKS87_20215	COG0280	phosphate acetyltransferase
MKS87_20220	COG3253	May function as heme-dependent peroxidase
MKS87_20225	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_20230	COG0436	Aminotransferase
MKS87_20235	COG2814	Major facilitator Superfamily
MKS87_20240	COG0151	Belongs to the GarS family
MKS87_20245	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_20250	COG1917	Cupin 2, conserved barrel domain protein
MKS87_20255	COG0077	Prephenate dehydratase
MKS87_20260	COG2814	Major facilitator Superfamily
MKS87_20265	COG0833	amino acid
MKS87_20270	COG4187	Peptidase family M20/M25/M40
MKS87_20275	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_20280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MKS87_20290	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MKS87_20295	COG1091	dTDP-4-dehydrorhamnose reductase activity
MKS87_20300	COG1088	dTDP-glucose 4,6-dehydratase activity
MKS87_20305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKS87_20310	COG3980	spore coat polysaccharide biosynthesis protein
MKS87_20315	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
MKS87_20320	COG2089	acid synthase
MKS87_20325	COG0456	acetyltransferase
MKS87_20330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MKS87_20335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKS87_20340	COG0463	Glycosyl transferase, family 2
MKS87_20350	COG2363	Small membrane protein
MKS87_20355	COG2233	PERMEase
MKS87_20365	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_20370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKS87_20375	COG1216	Glycosyl transferase, family 2
MKS87_20390	COG1695	Transcriptional regulator
MKS87_20395	COG0351	phosphomethylpyrimidine kinase
MKS87_20405	COG1621	beta-fructofuranosidase activity
MKS87_20410	COG1263	PTS System
MKS87_20410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_20415	COG2116	formate transmembrane transporter activity
MKS87_20420	COG3711	transcriptional antiterminator
MKS87_20430	COG1404	Belongs to the peptidase S8 family
MKS87_20435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKS87_20440	COG0778	Nitroreductase
MKS87_20445	COG0772	Belongs to the SEDS family
MKS87_20455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MKS87_20460	COG1845	cytochrome c oxidase, subunit III
MKS87_20465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKS87_20470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MKS87_20475	COG2261	transglycosylase associated protein
MKS87_20480	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MKS87_20485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKS87_20490	COG2246	polysaccharide biosynthetic process
MKS87_20495	COG1309	transcriptional regulator
MKS87_20505	COG3162	membrane
MKS87_20510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKS87_20515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MKS87_20520	COG2837	iron assimilation
MKS87_20525	COG2822	iron ion transport
MKS87_20530	COG0672	)-iron permease
MKS87_20535	COG0352	thiamine-phosphate diphosphorylase activity
MKS87_20540	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKS87_20545	COG0583	DNA-binding transcription factor activity
MKS87_20550	COG1380	Effector of murein hydrolase LrgA
MKS87_20555	COG1346	cytolysis
MKS87_20560	COG2814	Major facilitator Superfamily
MKS87_20565	COG4895	conserved protein (DUF2196)
MKS87_20570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MKS87_20575	COG0346	lactoylglutathione lyase activity
MKS87_20580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKS87_20585	COG1404	Belongs to the peptidase S8 family
MKS87_20590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_20590	COG1263	PTS System
MKS87_20595	COG3711	transcriptional antiterminator
MKS87_20600	COG1442	glycosyl transferase family 8
MKS87_20605	COG5522	Integral membrane protein (intg_mem_TP0381)
MKS87_20610	COG1846	Transcriptional regulator
MKS87_20615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKS87_20620	COG2234	aminopeptidase activity
MKS87_20635	COG2814	Major facilitator Superfamily
MKS87_20640	COG2357	RelA SpoT domain protein
MKS87_20645	COG1575	Belongs to the MenA family. Type 1 subfamily
MKS87_20660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MKS87_20665	COG1696	Membrane protein involved in D-alanine export
MKS87_20670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKS87_20675	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKS87_20680	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKS87_20685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MKS87_20690	COG1486	melibiose metabolic process
MKS87_20695	COG1447	Phosphotransferase system cellobiose-specific component IIA
MKS87_20700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKS87_20705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKS87_20710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MKS87_20710	COG3711	transcriptional antiterminator
MKS87_20720	COG2094	Belongs to the DNA glycosylase MPG family
MKS87_20725	COG0753	catalase activity
MKS87_20730	COG2814	Major facilitator Superfamily
MKS87_20735	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MKS87_20740	COG1131	(ABC) transporter
MKS87_20760	COG1595	DNA-templated transcription, initiation
MKS87_20765	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MKS87_20770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MKS87_20775	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MKS87_20780	COG4988	ABC transporter
MKS87_20785	COG1294	oxidase, subunit
MKS87_20790	COG1271	oxidase subunit
MKS87_20795	COG3493	citrate carrier protein
MKS87_20800	COG0501	Belongs to the peptidase M48B family
MKS87_20810	COG0726	polysaccharide deacetylase
MKS87_20815	COG3842	ATPase activity
MKS87_20820	COG2508	Transcriptional regulator
MKS87_20825	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_20830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKS87_20840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKS87_20845	COG1881	PFAM PEBP family protein
MKS87_20850	COG0583	DNA-binding transcription factor activity
MKS87_20860	COG4585	Histidine kinase
MKS87_20865	COG2197	response regulator
MKS87_20870	COG2195	Cleaves the N-terminal amino acid of tripeptides
MKS87_20880	COG4894	glucomannan catabolic process
MKS87_20885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKS87_20890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKS87_20895	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_20900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MKS87_20905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKS87_20910	COG2610	gluconate transmembrane transporter activity
MKS87_20915	COG0500	methyltransferase
MKS87_20920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKS87_20935	COG0753	catalase activity
MKS87_20935	COG0693	protein deglycase activity
MKS87_20940	COG2851	Citrate transporter
MKS87_20945	COG2273	Hydrolase Family 16
MKS87_20950	COG3711	transcriptional antiterminator
MKS87_20960	COG2270	Major facilitator Superfamily
MKS87_20965	COG0513	Belongs to the DEAD box helicase family
MKS87_20970	COG3401	FG-GAP repeat protein
MKS87_20970	COG2755	lipolytic protein G-D-S-L family
MKS87_21025	COG0697	spore germination
MKS87_21030	COG0589	response to stress
MKS87_21035	COG2723	6-phospho-beta-galactosidase activity
MKS87_21040	COG2190	(PTS) system
MKS87_21040	COG1263	PTS System
MKS87_21040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MKS87_21055	COG5444	nuclease activity
MKS87_21070	COG3507	Belongs to the glycosyl hydrolase 43 family
MKS87_21085	COG2986	histidine ammonia-lyase
MKS87_21090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MKS87_21095	COG1228	amidohydrolase
MKS87_21100	COG0010	Belongs to the arginase family
MKS87_21105	COG0833	amino acid
MKS87_21110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MKS87_21115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKS87_21120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKS87_21125	COG2390	Transcriptional regulator
MKS87_21135	COG3192	ethanolamine utilization protein
MKS87_21140	COG2079	MmgE PrpD family protein
MKS87_21145	COG1473	amidohydrolase
MKS87_21150	COG1126	abc transporter atp-binding protein
MKS87_21155	COG0765	amino acid transport
MKS87_21160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MKS87_21165	COG0456	acetyltransferase
MKS87_21170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKS87_21180	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MKS87_21185	COG0561	phosphatase activity
MKS87_21215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MKS87_21220	COG5294	Protein conserved in bacteria
MKS87_21225	COG0577	efflux transmembrane transporter activity
MKS87_21230	COG1136	(ABC) transporter
MKS87_21235	COG2205	protein histidine kinase activity
MKS87_21240	COG0745	RESPONSE REGULATOR receiver
MKS87_21245	COG0191	fructose-bisphosphate aldolase activity
MKS87_21250	COG1082	Xylose isomerase domain protein TIM barrel
MKS87_21255	COG1082	Xylose isomerase domain protein TIM barrel
MKS87_21260	COG0673	inositol 2-dehydrogenase activity
MKS87_21265	COG2814	Major facilitator Superfamily
MKS87_21270	COG1082	Xylose isomerase domain protein TIM barrel
MKS87_21275	COG3962	Belongs to the TPP enzyme family
MKS87_21280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKS87_21290	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_21295	COG1349	DNA-binding transcription factor activity
MKS87_21300	COG0667	Aldo Keto reductase
MKS87_21315	COG2814	Major facilitator Superfamily
MKS87_21320	COG0326	Molecular chaperone. Has ATPase activity
MKS87_21330	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_21335	COG1309	transcriptional regulator
MKS87_21340	COG1012	belongs to the aldehyde dehydrogenase family
MKS87_21345	COG1714	RDD family
MKS87_21350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MKS87_21360	COG1714	RDD family
MKS87_21365	COG2311	Membrane
MKS87_21370	COG1917	Cupin 2, conserved barrel domain protein
MKS87_21375	COG1309	transcriptional regulator
MKS87_21380	COG1028	Short-chain dehydrogenase reductase Sdr
MKS87_21385	COG1846	Transcriptional regulator
MKS87_21390	COG1380	Effector of murein hydrolase LrgA
MKS87_21395	COG1346	cytolysis
MKS87_21400	COG5039	Polysaccharide pyruvyl transferase
MKS87_21405	COG1929	Belongs to the glycerate kinase type-1 family
MKS87_21410	COG1802	Transcriptional regulator
MKS87_21415	COG1070	Carbohydrate kinase
MKS87_21420	COG2610	gluconate transmembrane transporter activity
MKS87_21425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKS87_21430	COG0450	alkyl hydroperoxide reductase
MKS87_21435	COG3634	alkyl hydroperoxide reductase activity
MKS87_21445	COG2723	6-phospho-beta-galactosidase activity
MKS87_21450	COG2190	(PTS) system
MKS87_21460	COG2188	Transcriptional regulator
MKS87_21475	COG1131	(ABC) transporter
MKS87_21480	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MKS87_21515	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKS87_21530	COG1063	alcohol dehydrogenase
MKS87_21550	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MKS87_21555	COG0456	acetyltransferase
MKS87_21560	COG0457	Tetratricopeptide repeat
MKS87_21570	COG0010	Belongs to the arginase family
MKS87_21575	COG0833	amino acid
MKS87_21580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MKS87_21585	COG3829	transcription factor binding
MKS87_21590	COG5002	protein histidine kinase activity
MKS87_21595	COG0745	RESPONSE REGULATOR receiver
MKS87_21615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKS87_21620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MKS87_21625	COG4853	Protein conserved in bacteria
MKS87_21630	COG4863	YycH protein
MKS87_21635	COG5002	protein histidine kinase activity
MKS87_21640	COG0745	RESPONSE REGULATOR receiver
MKS87_21670	COG0346	lactoylglutathione lyase activity
MKS87_21675	COG0305	Participates in initiation and elongation during chromosome replication
MKS87_21690	COG3093	addiction module antidote protein HigA
MKS87_21695	COG2807	transmembrane transport
MKS87_21700	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKS87_21705	COG0359	binds to the 23S rRNA
MKS87_21710	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MKS87_21715	COG4241	membrane
MKS87_21725	COG5577	PFAM Coat F domain
MKS87_21730	COG1733	regulation of RNA biosynthetic process
MKS87_21735	COG1227	inorganic diphosphatase activity
MKS87_21745	COG2271	Major facilitator Superfamily
MKS87_21750	COG4978	Transcriptional regulator
MKS87_21750	COG0789	Transcriptional regulator
MKS87_21760	COG4319	ketosteroid isomerase
MKS87_21765	COG1357	PFAM Pentapeptide repeats (8 copies)
MKS87_21770	COG2814	Major facilitator Superfamily
MKS87_21775	COG0583	DNA-binding transcription factor activity
MKS87_21780	COG2153	protein acetylation
MKS87_21795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MKS87_21800	COG1846	Transcriptional regulator
MKS87_21805	COG2153	protein acetylation
MKS87_21810	COG2364	Membrane
MKS87_21815	COG0456	acetyltransferase
MKS87_21820	COG2315	Protein conserved in bacteria
MKS87_21825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKS87_21835	COG2814	Major facilitator Superfamily
MKS87_21860	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MKS87_21865	COG1331	Highly conserved protein containing a thioredoxin domain
MKS87_21875	COG1331	Highly conserved protein containing a thioredoxin domain
MKS87_21880	COG1266	CAAX protease self-immunity
MKS87_21885	COG2814	Major facilitator Superfamily
MKS87_21885	COG0477	Major facilitator Superfamily
MKS87_21890	COG0110	maltose O-acetyltransferase activity
MKS87_21895	COG0346	lactoylglutathione lyase activity
MKS87_21900	COG1609	Transcriptional regulator
MKS87_21905	COG0708	Exodeoxyribonuclease III
MKS87_21910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKS87_21915	COG0629	single-stranded DNA binding
MKS87_21920	COG0360	Binds together with S18 to 16S ribosomal RNA
MKS87_21925	COG0012	GTP binding
MKS87_21930	COG0243	molybdopterin cofactor binding
MKS87_21935	COG4481	Protein conserved in bacteria
MKS87_21940	COG3949	Membrane
MKS87_21950	COG1475	DNA binding
MKS87_21955	COG1192	Involved in chromosome partitioning
MKS87_21965	COG1475	DNA binding
MKS87_21970	COG0357	Ribosomal RNA small subunit methyltransferase G
MKS87_21975	COG0445	tRNA wobble uridine modification
MKS87_21980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKS87_21985	COG1847	R3H domain protein
MKS87_21990	COG0706	membrane insertase activity
MKS87_21995	COG0594	ribonuclease P activity