locus-tag	class	description
CD007_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CD007_00010	COG0592	DNA-directed DNA polymerase activity
CD007_00015	COG2501	S4 domain
CD007_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CD007_00030	COG0187	DNA topoisomerase II activity
CD007_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CD007_00070	COG0517	IMP dehydrogenase activity
CD007_00070	COG0516	GMP reductase activity
CD007_00075	COG1686	Belongs to the peptidase S11 family
CD007_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CD007_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CD007_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CD007_00100	COG1428	Deoxynucleoside kinase
CD007_00105	COG1428	Deoxynucleoside kinase
CD007_00110	COG3858	chitin binding
CD007_00110	COG1388	LysM domain
CD007_00115	COG1335	isochorismatase
CD007_00120	COG0590	tRNA wobble adenosine to inosine editing
CD007_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CD007_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CD007_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CD007_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CD007_00190	COG3853	Toxic anion resistance protein (TelA)
CD007_00195	COG1982	Orn Lys Arg decarboxylase major
CD007_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CD007_00205	COG3870	Protein conserved in bacteria
CD007_00210	COG1728	Protein conserved in bacteria
CD007_00215	COG0470	DNA polymerase III
CD007_00220	COG1774	PSP1 C-terminal conserved region
CD007_00225	COG4467	Involved in initiation control of chromosome replication
CD007_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CD007_00235	COG2827	Endonuclease containing a URI domain
CD007_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CD007_00245	COG2002	toxin-antitoxin pair type II binding
CD007_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CD007_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CD007_00255	COG0084	hydrolase, TatD family'
CD007_00260	COG3583	domain protein
CD007_00260	COG3584	3D domain protein
CD007_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CD007_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CD007_00280	COG4466	Protein conserved in bacteria
CD007_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CD007_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CD007_00300	COG0251	oxidation-reduction process
CD007_00305	COG2088	sporulation resulting in formation of a cellular spore
CD007_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CD007_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CD007_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CD007_00325	COG0193	aminoacyl-tRNA hydrolase activity
CD007_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CD007_00340	COG2002	toxin-antitoxin pair type II binding
CD007_00345	COG2244	polysaccharide biosynthetic process
CD007_00350	COG3956	TIGRFAM MazG family protein
CD007_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CD007_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CD007_00375	COG1098	S1 RNA binding domain
CD007_00390	COG2208	phosphoserine phosphatase activity
CD007_00395	COG2304	oxidoreductase activity
CD007_00400	COG0515	serine threonine protein kinase
CD007_00405	COG0037	tRNA processing
CD007_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CD007_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CD007_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CD007_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CD007_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CD007_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CD007_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
CD007_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CD007_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CD007_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CD007_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CD007_00470	COG1396	sequence-specific DNA binding
CD007_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CD007_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CD007_00545	COG4463	regulation of RNA biosynthetic process
CD007_00550	COG3880	PFAM UvrB UvrC protein
CD007_00555	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CD007_00560	COG0542	response to heat
CD007_00565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CD007_00570	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CD007_00575	COG4956	integral membrane protein (PIN domain superfamily)
CD007_00580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CD007_00585	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CD007_00590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CD007_00600	COG1045	serine acetyltransferase
CD007_00605	COG0215	cysteine-tRNA ligase activity
CD007_00610	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CD007_00615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CD007_00620	COG3688	RNA-binding protein containing a PIN domain
CD007_00625	COG1595	DNA-templated transcription, initiation
CD007_00630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CD007_00635	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CD007_00640	COG0250	Participates in transcription elongation, termination and antitermination
CD007_00645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CD007_00650	COG0081	regulation of translation
CD007_00655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CD007_00660	COG0222	ribosome binding
CD007_00665	COG2813	Specifically methylates the guanine in position
CD007_00670	COG0085	RNA polymerase activity
CD007_00675	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CD007_00680	COG1358	cellular component organization or biogenesis
CD007_00685	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CD007_00690	COG0049	tRNA binding
CD007_00695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CD007_00700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CD007_00705	COG0596	Alpha beta hydrolase
CD007_00710	COG0051	transcription antitermination factor activity, RNA binding
CD007_00715	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CD007_00720	COG0088	Forms part of the polypeptide exit tunnel
CD007_00725	COG0089	rRNA binding
CD007_00730	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CD007_00735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CD007_00740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CD007_00745	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CD007_00750	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CD007_00755	COG0255	Belongs to the universal ribosomal protein uL29 family
CD007_00760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CD007_00765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CD007_00775	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CD007_00785	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CD007_00790	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CD007_00795	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CD007_00800	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CD007_00805	COG1841	ribosomal large subunit assembly
CD007_00810	COG0200	Binds to the 23S rRNA
CD007_00815	COG0201	protein transport
CD007_00820	COG0563	adenylate kinase activity
CD007_00825	COG0024	Methionine aminopeptidase
CD007_00830	COG2163	COG2163 Ribosomal protein L14E L6E L27E
CD007_00835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CD007_00840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CD007_00845	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CD007_00850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CD007_00855	COG0202	RNA polymerase activity
CD007_00860	COG0203	ribosomal protein L17
CD007_00865	COG1122	ATPase activity
CD007_00870	COG1122	ATPase activity
CD007_00875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CD007_00880	COG0101	tRNA pseudouridine synthase activity
CD007_00885	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CD007_00890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CD007_00895	COG2226	methyltransferase
CD007_00905	COG0860	N-Acetylmuramoyl-L-alanine amidase
CD007_00910	COG0489	protein tyrosine kinase activity
CD007_00920	COG2194	sulfuric ester hydrolase activity
CD007_00925	COG0726	polysaccharide deacetylase
CD007_01035	COG0659	secondary active sulfate transmembrane transporter activity
CD007_01040	COG0385	Bile acid
CD007_01045	COG2819	hydrolase of the alpha beta superfamily
CD007_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CD007_01065	COG2207	Transcriptional regulator
CD007_01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CD007_01070	COG3876	Protein conserved in bacteria
CD007_01075	COG1472	Belongs to the glycosyl hydrolase 3 family
CD007_01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CD007_01085	COG1263	PTS System
CD007_01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_01090	COG1737	Transcriptional regulator
CD007_01095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CD007_01100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_01105	COG1683	Conserved Protein
CD007_01135	COG1595	DNA-templated transcription, initiation
CD007_01140	COG5662	AntiSigma factor
CD007_01145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CD007_01150	COG4856	YbbR-like protein
CD007_01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CD007_01160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CD007_01165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CD007_01170	COG2169	Transcriptional regulator
CD007_01175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CD007_01180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CD007_01185	COG3002	Belongs to the UPF0753 family
CD007_01190	COG0288	reversible hydration of carbon dioxide
CD007_01200	COG5609	conserved protein (DUF2294)
CD007_01205	COG0640	Transcriptional regulator
CD007_01210	COG2814	Major facilitator Superfamily
CD007_01225	COG0515	serine threonine protein kinase
CD007_01240	COG1113	amino acid transport
CD007_01255	COG2602	Beta-lactamase
CD007_01260	COG2124	cytochrome p450
CD007_01270	COG0531	amino acid
CD007_01275	COG0584	glycerophosphoryl diester phosphodiesterase
CD007_01280	COG2271	Major facilitator Superfamily
CD007_01295	COG0456	acetyltransferase
CD007_01295	COG1846	Transcriptional regulator
CD007_01300	COG2271	Major facilitator Superfamily
CD007_01310	COG3409	Peptidoglycan-binding domain 1 protein
CD007_01315	COG0697	spore germination
CD007_01320	COG1917	Cupin 2, conserved barrel domain protein
CD007_01320	COG2207	Transcriptional regulator
CD007_01325	COG1397	ADP-ribosylglycohydrolase
CD007_01330	COG5444	nuclease activity
CD007_01335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CD007_01340	COG3591	Belongs to the peptidase S1B family
CD007_01350	COG0596	Alpha beta hydrolase
CD007_01355	COG1183	phosphatidylcholine synthase activity
CD007_01360	COG0586	Pfam SNARE associated Golgi protein
CD007_01365	COG0688	phosphatidylethanolamine metabolic process
CD007_01375	COG2312	Erythromycin esterase
CD007_01385	COG1301	dicarboxylic acid transport
CD007_01390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_01390	COG2190	(PTS) system
CD007_01390	COG1263	PTS System
CD007_01395	COG0363	glucosamine-6-phosphate deaminase activity
CD007_01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CD007_01415	COG0833	amino acid
CD007_01420	COG2040	homocysteine
CD007_01430	COG1115	amino acid carrier protein
CD007_01435	COG2066	Belongs to the glutaminase family
CD007_01440	COG4191	Histidine kinase
CD007_01445	COG0784	Response regulator, receiver
CD007_01450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CD007_01455	COG1012	belongs to the aldehyde dehydrogenase family
CD007_01460	COG2271	Major facilitator Superfamily
CD007_01465	COG4948	Mandelate Racemase Muconate Lactonizing
CD007_01470	COG2186	Transcriptional regulator
CD007_01475	COG2721	sulfolactate sulfo-lyase activity
CD007_01480	COG3173	Aminoglycoside phosphotransferase
CD007_01490	COG0697	spore germination
CD007_01495	COG0745	RESPONSE REGULATOR receiver
CD007_01500	COG2205	protein histidine kinase activity
CD007_01505	COG1131	(ABC) transporter
CD007_01520	COG3773	Cell wall hydrolase
CD007_01525	COG2304	oxidoreductase activity
CD007_01535	COG3540	Alkaline phosphatase
CD007_01540	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CD007_01545	COG0805	protein transport
CD007_01550	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CD007_01555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CD007_01560	COG0477	Major facilitator Superfamily
CD007_01565	COG1309	transcriptional regulator
CD007_01570	COG0252	asparaginase activity
CD007_01575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CD007_01580	COG1714	RDD family
CD007_01585	COG3012	SEC-C Motif Domain Protein
CD007_01585	COG1405	negative regulation of cell septum assembly
CD007_01590	COG3290	protein histidine kinase activity
CD007_01595	COG3279	Response regulator of the LytR AlgR family
CD007_01600	COG4555	ABC transporter
CD007_01605	COG1668	transmembrane transport
CD007_01610	COG0667	Aldo Keto reductase
CD007_01620	COG1595	DNA-templated transcription, initiation
CD007_01630	COG1595	DNA-templated transcription, initiation
CD007_01635	COG1876	peptidase activity
CD007_01640	COG0457	Tetratricopeptide repeat
CD007_01645	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_01650	COG0366	Alpha amylase catalytic
CD007_01655	COG0803	Belongs to the bacterial solute-binding protein 9 family
CD007_01660	COG1121	(ABC) transporter
CD007_01665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CD007_01670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CD007_01675	COG2310	stress, protein
CD007_01680	COG2310	stress, protein
CD007_01685	COG2310	stress, protein
CD007_01690	COG0861	Integral membrane protein TerC family
CD007_01700	COG3853	Toxic anion resistance protein (TelA)
CD007_01705	COG0477	Major facilitator Superfamily
CD007_01715	COG2814	Major facilitator Superfamily
CD007_01720	COG0640	Transcriptional regulator
CD007_01725	COG0517	IMP dehydrogenase activity
CD007_01725	COG4175	Glycine betaine
CD007_01730	COG4176	ABC-type proline glycine betaine transport system permease component
CD007_01735	COG2113	Glycine betaine
CD007_01740	COG1473	amidohydrolase
CD007_01745	COG1288	antiporter activity
CD007_01755	COG0366	Alpha amylase catalytic
CD007_01760	COG0039	L-malate dehydrogenase activity
CD007_01765	COG1620	l-lactate permease
CD007_01770	COG2814	Major facilitator Superfamily
CD007_01775	COG1846	Transcriptional regulator
CD007_01780	COG1280	lysine exporter protein (LysE YggA)
CD007_01785	COG3403	YqcI/YcgG family
CD007_01790	COG1113	amino acid transport
CD007_01795	COG3665	Urea carboxylase-associated protein
CD007_01800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CD007_01805	COG1660	Displays ATPase and GTPase activities
CD007_01810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CD007_01815	COG2226	methyltransferase
CD007_01820	COG0583	DNA-binding transcription factor activity
CD007_01825	COG3458	cephalosporin-C deacetylase activity
CD007_01830	COG3541	Predicted nucleotidyltransferase
CD007_01835	COG0506	proline dehydrogenase activity
CD007_01840	COG1012	belongs to the aldehyde dehydrogenase family
CD007_01845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CD007_01850	COG2508	Transcriptional regulator
CD007_01855	COG3689	TIGRFAM TIGR03943 family protein
CD007_01860	COG0701	Predicted permease
CD007_01865	COG2267	carboxylic ester hydrolase activity
CD007_01870	COG0492	ferredoxin-NADP+ reductase activity
CD007_01875	COG1587	Uroporphyrinogen-III synthase
CD007_01875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CD007_01880	COG2146	nitrite reductase [NAD(P)H] activity
CD007_01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CD007_01890	COG0243	molybdopterin cofactor binding
CD007_01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CD007_01900	COG2223	nitrite transmembrane transporter activity
CD007_01905	COG1469	GTP cyclohydrolase I activity
CD007_01910	COG1376	ErfK ybiS ycfS ynhG family protein
CD007_01920	COG0523	cobalamin synthesis protein
CD007_01925	COG0765	amino acid transport
CD007_01930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CD007_01940	COG1714	RDD family
CD007_01950	COG2723	6-phospho-beta-galactosidase activity
CD007_01960	COG3209	COG3209 Rhs family protein
CD007_01965	COG3290	protein histidine kinase activity
CD007_01965	COG0840	transmembrane signaling receptor activity
CD007_01970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CD007_01975	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CD007_01980	COG1733	regulation of RNA biosynthetic process
CD007_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_02000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CD007_02005	COG2814	Major facilitator Superfamily
CD007_02015	COG0697	spore germination
CD007_02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CD007_02030	COG2364	Membrane
CD007_02035	COG1126	abc transporter atp-binding protein
CD007_02040	COG0765	amino acid transport
CD007_02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CD007_02050	COG0583	DNA-binding transcription factor activity
CD007_02055	COG0163	prenyltransferase activity
CD007_02060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CD007_02075	COG0596	Alpha beta hydrolase
CD007_02080	COG3104	oligopeptide transport
CD007_02085	COG5434	Belongs to the glycosyl hydrolase 28 family
CD007_02095	COG0697	spore germination
CD007_02105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CD007_02110	COG1136	(ABC) transporter
CD007_02115	COG0577	efflux transmembrane transporter activity
CD007_02120	COG0745	RESPONSE REGULATOR receiver
CD007_02125	COG3850	Histidine kinase
CD007_02125	COG5002	protein histidine kinase activity
CD007_02130	COG0457	Tetratricopeptide repeat
CD007_02150	COG0527	aspartate kinase activity
CD007_02155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_02160	COG4605	iron ion homeostasis
CD007_02165	COG4604	ABC transporter, ATP-binding protein
CD007_02170	COG4607	ABC-type enterochelin transport system periplasmic component
CD007_02175	COG2814	Major facilitator Superfamily
CD007_02180	COG1309	transcriptional regulator
CD007_02185	COG0778	Nitroreductase
CD007_02190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CD007_02195	COG0640	Transcriptional regulator
CD007_02200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CD007_02205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CD007_02210	COG1012	belongs to the aldehyde dehydrogenase family
CD007_02215	COG4975	Glucose uptake
CD007_02220	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_02225	COG4549	nuclear export factor GLE1
CD007_02230	COG1276	copper resistance
CD007_02230	COG2372	response to copper ion
CD007_02235	COG1349	DNA-binding transcription factor activity
CD007_02245	COG2213	PTS system mannitol-specific
CD007_02250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_02255	COG0246	Mannitol dehydrogenase
CD007_02260	COG0473	3-isopropylmalate dehydrogenase activity
CD007_02265	COG0681	Belongs to the peptidase S26 family
CD007_02270	COG0412	Dienelactone hydrolase
CD007_02275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CD007_02285	COG0561	phosphatase activity
CD007_02290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CD007_02295	COG1914	H( )-stimulated, divalent metal cation uptake system
CD007_02300	COG4336	lyase activity
CD007_02305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CD007_02310	COG1984	allophanate hydrolase subunit 2
CD007_02315	COG1414	Transcriptional regulator
CD007_02320	COG2755	lipolytic protein G-D-S-L family
CD007_02330	COG2329	Antibiotic biosynthesis monooxygenase
CD007_02335	COG0768	penicillin binding
CD007_02340	COG4989	oxidoreductase activity
CD007_02345	COG3711	transcriptional antiterminator
CD007_02350	COG0318	PFAM AMP-dependent synthetase and ligase
CD007_02355	COG2226	methyltransferase
CD007_02360	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_02365	COG1917	Cupin 2, conserved barrel domain protein
CD007_02370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_02375	COG3871	stress protein (general stress protein 26)
CD007_02385	COG2814	Major facilitator Superfamily
CD007_02390	COG1522	sequence-specific DNA binding
CD007_02395	COG0551	DNA topoisomerase type I activity
CD007_02395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CD007_02400	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CD007_02405	COG3706	GGDEF domain
CD007_02410	COG5298	Protein conserved in bacteria
CD007_02415	COG1215	transferase activity, transferring glycosyl groups
CD007_02425	COG0531	amino acid
CD007_02430	COG0494	nUDIX hydrolase
CD007_02435	COG0028	Belongs to the TPP enzyme family
CD007_02445	COG1914	H( )-stimulated, divalent metal cation uptake system
CD007_02450	COG2261	transglycosylase associated protein
CD007_02455	COG4876	unkown
CD007_02460	COG2217	Heavy metal translocating P-type atpase
CD007_02465	COG3729	General stress protein
CD007_02470	COG0662	Cupin 2, conserved barrel domain protein
CD007_02475	COG2329	Antibiotic biosynthesis monooxygenase
CD007_02480	COG3546	catalase activity
CD007_02485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CD007_02490	COG3290	protein histidine kinase activity
CD007_02495	COG4565	transcriptional regulatory protein
CD007_02500	COG1301	dicarboxylic acid transport
CD007_02505	COG0628	permease
CD007_02510	COG1131	(ABC) transporter
CD007_02515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CD007_02525	COG1960	acyl-CoA dehydrogenase activity
CD007_02540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CD007_02545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_02550	COG1181	Belongs to the D-alanine--D-alanine ligase family
CD007_02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CD007_02565	COG0513	Belongs to the DEAD box helicase family
CD007_02570	COG3402	PFAM membrane-flanked domain
CD007_02575	COG3428	Bacterial PH domain
CD007_02580	COG0705	Rhomboid family
CD007_02585	COG0736	holo-[acyl-carrier-protein] synthase activity
CD007_02590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CD007_02595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CD007_02600	COG0864	Transcriptional regulator
CD007_02605	COG2337	Toxic component of a toxin-antitoxin (TA) module
CD007_02610	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_02615	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_02620	COG2172	sigma factor antagonist activity
CD007_02625	COG2208	phosphoserine phosphatase activity
CD007_02630	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_02635	COG2172	sigma factor antagonist activity
CD007_02640	COG1191	sigma factor activity
CD007_02645	COG2208	phosphoserine phosphatase activity
CD007_02650	COG2183	response to ionizing radiation
CD007_02660	COG3091	SprT-like family
CD007_02700	COG0582	viral genome integration into host DNA
CD007_02715	COG0457	Tetratricopeptide repeat
CD007_02745	COG5444	nuclease activity
CD007_02755	COG1476	TRANSCRIPTIONal
CD007_02765	COG3239	Fatty acid desaturase
CD007_02770	COG1278	Cold shock
CD007_02775	COG1329	Transcriptional regulator
CD007_02785	COG0697	spore germination
CD007_02790	COG2207	Transcriptional regulator
CD007_02790	COG1917	Cupin 2, conserved barrel domain protein
CD007_02795	COG0697	spore germination
CD007_02800	COG3708	Transcriptional regulator
CD007_02800	COG2207	Transcriptional regulator
CD007_02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CD007_02810	COG0477	Major facilitator Superfamily
CD007_02820	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CD007_02840	COG1309	transcriptional regulator
CD007_02845	COG0697	spore germination
CD007_02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CD007_02855	COG2030	dehydratase
CD007_02860	COG3545	Serine hydrolase
CD007_02865	COG1733	regulation of RNA biosynthetic process
CD007_02870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CD007_02875	COG1733	regulation of RNA biosynthetic process
CD007_02880	COG2249	NAD(P)H dehydrogenase (quinone) activity
CD007_02885	COG2814	Major facilitator Superfamily
CD007_02890	COG1309	transcriptional regulator
CD007_02895	COG0640	Transcriptional regulator
CD007_02900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CD007_02910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_02915	COG0697	spore germination
CD007_02920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CD007_02925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CD007_02930	COG0640	Transcriptional regulator
CD007_02935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CD007_02950	COG4585	Histidine kinase
CD007_02955	COG2197	response regulator
CD007_02960	COG2409	Drug exporters of the RND superfamily
CD007_02965	COG0596	Alpha beta hydrolase
CD007_02970	COG1811	Na channel or pump
CD007_02975	COG0789	Transcriptional regulator
CD007_02975	COG4978	Transcriptional regulator
CD007_02980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CD007_02985	COG0778	Nitroreductase
CD007_02990	COG0346	lactoylglutathione lyase activity
CD007_02995	COG2259	Doxx family
CD007_03000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_03020	COG2323	membrane
CD007_03025	COG2323	membrane
CD007_03030	COG0071	Belongs to the small heat shock protein (HSP20) family
CD007_03045	COG1309	transcriptional regulator
CD007_03055	COG0456	acetyltransferase
CD007_03065	COG1113	amino acid transport
CD007_03070	COG2318	DinB family
CD007_03075	COG1846	Transcriptional regulator
CD007_03080	COG2409	Drug exporters of the RND superfamily
CD007_03080	COG1033	growth of symbiont in host cell
CD007_03085	COG0778	Nitroreductase
CD007_03090	COG1846	Transcriptional regulator
CD007_03095	COG2814	Major facilitator Superfamily
CD007_03100	COG0730	response to heat
CD007_03105	COG1802	Transcriptional regulator
CD007_03110	COG1388	LysM domain
CD007_03110	COG3858	chitin binding
CD007_03115	COG1819	glycosyl
CD007_03125	COG1785	Belongs to the alkaline phosphatase family
CD007_03130	COG5646	InterPro IPR014922
CD007_03140	COG0454	-acetyltransferase
CD007_03145	COG1078	dGTPase activity
CD007_03150	COG1388	LysM domain
CD007_03155	COG2814	Major facilitator Superfamily
CD007_03160	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CD007_03165	COG1447	Phosphotransferase system cellobiose-specific component IIA
CD007_03170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CD007_03175	COG2723	6-phospho-beta-galactosidase activity
CD007_03180	COG2188	Transcriptional regulator
CD007_03185	COG1940	carbohydrate kinase activity
CD007_03190	COG1482	cell wall glycoprotein biosynthetic process
CD007_03195	COG4124	Belongs to the glycosyl hydrolase 26 family
CD007_03240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CD007_03245	COG0802	atpase or kinase
CD007_03250	COG1214	PFAM Peptidase M22, glycoprotease
CD007_03255	COG0456	acetyltransferase
CD007_03260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CD007_03265	COG0488	(ABC) transporter
CD007_03270	COG0315	cyclic pyranopterin monophosphate synthase activity
CD007_03275	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CD007_03280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CD007_03285	COG0805	protein transport
CD007_03300	COG1266	CAAX protease self-immunity
CD007_03305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CD007_03310	COG0459	protein refolding
CD007_03320	COG1073	alpha beta
CD007_03330	COG1063	alcohol dehydrogenase
CD007_03335	COG2211	Major facilitator Superfamily
CD007_03340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CD007_03345	COG1842	Phage shock protein A
CD007_03350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CD007_03355	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CD007_03360	COG4260	virion core protein, lumpy skin disease virus
CD007_03370	COG2814	Major facilitator Superfamily
CD007_03375	COG1063	alcohol dehydrogenase
CD007_03380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CD007_03385	COG0823	Involved in the tonB-independent uptake of proteins
CD007_03400	COG2267	carboxylic ester hydrolase activity
CD007_03410	COG2132	Multicopper oxidase
CD007_03415	COG1113	amino acid transport
CD007_03425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CD007_03430	COG0714	Associated with various cellular activities
CD007_03435	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CD007_03440	COG1305	Transglutaminase-like
CD007_03445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CD007_03445	COG0519	Catalyzes the synthesis of GMP from XMP
CD007_03460	COG2252	PERMEase
CD007_03465	COG3064	Membrane
CD007_03475	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CD007_03485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CD007_03490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CD007_03495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CD007_03500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CD007_03505	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CD007_03510	COG0047	phosphoribosylformylglycinamidine synthase activity
CD007_03515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CD007_03520	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CD007_03525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CD007_03530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CD007_03535	COG0138	bifunctional purine biosynthesis protein purh
CD007_03540	COG0151	Belongs to the GarS family
CD007_03545	COG1522	sequence-specific DNA binding
CD007_03550	COG0531	amino acid
CD007_03560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CD007_03565	COG1470	cell adhesion involved in biofilm formation
CD007_03570	COG4496	protein, YerC YecD
CD007_03575	COG0069	glutamate synthase activity
CD007_03580	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CD007_03585	COG0210	DNA helicase
CD007_03590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CD007_03595	COG4851	CamS sex pheromone cAM373 precursor
CD007_03600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CD007_03605	COG1285	pathogenesis
CD007_03610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CD007_03615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CD007_03620	COG0154	amidase activity
CD007_03625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CD007_03635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CD007_03640	COG1597	lipid kinase activity
CD007_03645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CD007_03660	COG5444	nuclease activity
CD007_03665	COG3391	amine dehydrogenase activity
CD007_03670	COG0457	Tetratricopeptide repeat
CD007_03680	COG0217	transcriptional regulatory protein
CD007_03690	COG1309	transcriptional regulator
CD007_03695	COG3631	Ketosteroid isomerase-related protein
CD007_03715	COG3546	catalase activity
CD007_03720	COG0454	-acetyltransferase
CD007_03730	COG5578	integral membrane protein
CD007_03735	COG2972	Histidine kinase
CD007_03740	COG2207	Transcriptional regulator
CD007_03740	COG4753	response regulator
CD007_03745	COG1653	transport
CD007_03750	COG1175	transmembrane transport
CD007_03755	COG0395	ABC-type sugar transport system, permease component
CD007_03760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CD007_03765	COG2207	Transcriptional regulator
CD007_03770	COG2755	lipolytic protein G-D-S-L family
CD007_03780	COG5578	integral membrane protein
CD007_03785	COG3401	FG-GAP repeat protein
CD007_03790	COG3401	FG-GAP repeat protein
CD007_03795	COG2755	lipolytic protein G-D-S-L family
CD007_03800	COG1874	Beta-galactosidase
CD007_03810	COG1653	transport
CD007_03815	COG4209	transmembrane transport
CD007_03820	COG0395	ABC-type sugar transport system, permease component
CD007_03825	COG1486	melibiose metabolic process
CD007_03830	COG2323	membrane
CD007_03835	COG2329	Antibiotic biosynthesis monooxygenase
CD007_03840	COG0346	lactoylglutathione lyase activity
CD007_03855	COG5583	Uncharacterized small protein (DUF2292)
CD007_03860	COG0670	Belongs to the BI1 family
CD007_03865	COG0697	spore germination
CD007_03870	COG1846	Transcriptional regulator
CD007_03875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CD007_03890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CD007_03890	COG2124	cytochrome p450
CD007_03895	COG1368	sulfuric ester hydrolase activity
CD007_03900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CD007_03905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CD007_03910	COG1442	glycosyl transferase family 8
CD007_03915	COG1216	Glycosyl transferase, family 2
CD007_03920	COG1442	glycosyl transferase family 8
CD007_03925	COG2223	nitrite transmembrane transporter activity
CD007_03930	COG1011	Hydrolase
CD007_03935	COG0531	amino acid
CD007_03940	COG1012	belongs to the aldehyde dehydrogenase family
CD007_03945	COG0840	transmembrane signaling receptor activity
CD007_03950	COG0488	(ABC) transporter
CD007_03960	COG0789	Transcriptional regulator
CD007_03965	COG2814	Major facilitator Superfamily
CD007_03970	COG1404	Belongs to the peptidase S8 family
CD007_03985	COG0488	(ABC) transporter
CD007_03990	COG0513	Belongs to the DEAD box helicase family
CD007_03995	COG0456	acetyltransferase
CD007_04000	COG2130	NADP-dependent
CD007_04005	COG1120	ATPase activity
CD007_04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_04015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_04020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CD007_04040	COG3866	Pectate lyase
CD007_04045	COG0471	metal ion transport
CD007_04050	COG3290	protein histidine kinase activity
CD007_04055	COG4565	transcriptional regulatory protein
CD007_04060	COG3181	Tripartite tricarboxylate transporter family receptor
CD007_04065	COG2851	Citrate transporter
CD007_04070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_04075	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CD007_04080	COG1254	Belongs to the acylphosphatase family
CD007_04085	COG2258	MOSC domain
CD007_04105	COG0024	Methionine aminopeptidase
CD007_04110	COG1263	PTS System
CD007_04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_04115	COG1368	sulfuric ester hydrolase activity
CD007_04130	COG1115	amino acid carrier protein
CD007_04135	COG0531	amino acid
CD007_04150	COG0697	spore germination
CD007_04155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_04155	COG1263	PTS System
CD007_04160	COG0366	Alpha amylase catalytic
CD007_04165	COG2188	Transcriptional regulator
CD007_04170	COG0778	Nitroreductase
CD007_04175	COG0737	Belongs to the 5'-nucleotidase family
CD007_04180	COG0693	protein deglycase activity
CD007_04185	COG2814	Major facilitator Superfamily
CD007_04190	COG4840	Belongs to the UPF0435 family
CD007_04195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CD007_04200	COG4980	gas vesicle protein
CD007_04205	COG1295	ribonuclease BN
CD007_04210	COG0477	Major facilitator Superfamily
CD007_04215	COG0387	Pfam Sodium calcium exchanger
CD007_04225	COG0668	transmembrane transport
CD007_04230	COG0535	radical SAM domain protein
CD007_04240	COG0726	polysaccharide deacetylase
CD007_04245	COG2084	Dehydrogenase
CD007_04250	COG0598	Magnesium transport protein CorA
CD007_04255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CD007_04260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CD007_04270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CD007_04275	COG4637	Psort location Cytoplasmic, score
CD007_04280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CD007_04285	COG0022	dehydrogenase e1 component
CD007_04290	COG0508	dehydrogenase complex catalyzes the overall conversion of
CD007_04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CD007_04300	COG3284	Transcriptional regulator
CD007_04310	COG1742	UPF0060 membrane protein
CD007_04335	COG4842	Belongs to the WXG100 family
CD007_04340	COG1486	melibiose metabolic process
CD007_04345	COG1737	Transcriptional regulator
CD007_04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_04350	COG1263	PTS System
CD007_04355	COG5434	Belongs to the glycosyl hydrolase 28 family
CD007_04360	COG1132	(ABC) transporter
CD007_04365	COG1132	(ABC) transporter
CD007_04370	COG2259	Doxx family
CD007_04375	COG2514	catechol 2,3-dioxygenase activity
CD007_04380	COG4585	Histidine kinase
CD007_04385	COG2197	response regulator
CD007_04395	COG1131	(ABC) transporter
CD007_04400	COG1511	domain protein
CD007_04400	COG0842	Transport permease protein
CD007_04405	COG0842	Transport permease protein
CD007_04410	COG1695	Transcriptional regulator
CD007_04415	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CD007_04420	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CD007_04425	COG2318	DinB family
CD007_04430	COG2814	Major facilitator Superfamily
CD007_04435	COG1846	Transcriptional regulator
CD007_04440	COG0392	lysyltransferase activity
CD007_04440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CD007_04445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CD007_04450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_04455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_04460	COG0384	phenazine biosynthesis protein PhzF
CD007_04465	COG0778	Nitroreductase
CD007_04480	COG1090	epimerase
CD007_04485	COG2137	regulation of response to DNA damage stimulus
CD007_04495	COG2814	Major facilitator Superfamily
CD007_04510	COG3103	Sh3 type 3 domain protein
CD007_04515	COG5658	integral membrane protein
CD007_04520	COG0596	Alpha beta hydrolase
CD007_04525	COG0463	Glycosyl transferase, family 2
CD007_04530	COG4485	Bacterial membrane protein, YfhO
CD007_04535	COG1988	membrane-bound metal-dependent
CD007_04540	COG1194	a g-specific adenine glycosylase
CD007_04550	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_04565	COG3557	Belongs to the UPF0374 family
CD007_04570	COG1132	(ABC) transporter
CD007_04575	COG4129	membrane
CD007_04580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CD007_04585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CD007_04590	COG0735	belongs to the Fur family
CD007_04700	COG4326	sporulation control protein
CD007_04710	COG5577	PFAM Coat F domain
CD007_04720	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CD007_04725	COG0277	FAD linked oxidase domain protein
CD007_04735	COG0753	catalase activity
CD007_04740	COG1116	anion transmembrane transporter activity
CD007_04745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CD007_04750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CD007_04755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CD007_04765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CD007_04775	COG1476	TRANSCRIPTIONal
CD007_04785	COG3382	B3 4 domain protein
CD007_04790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CD007_04800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CD007_04805	COG0789	Transcriptional regulator
CD007_04810	COG1664	Polymer-forming cytoskeletal
CD007_04815	COG1664	Polymer-forming cytoskeletal
CD007_04820	COG2766	serine protein kinase
CD007_04825	COG2718	Belongs to the UPF0229 family
CD007_04830	COG1846	Transcriptional regulator
CD007_04835	COG1566	PFAM secretion protein HlyD family protein
CD007_04840	COG2814	Major facilitator Superfamily
CD007_04845	COG0655	NAD(P)H dehydrogenase (quinone) activity
CD007_04865	COG1725	Transcriptional regulator
CD007_04870	COG1131	(ABC) transporter
CD007_04875	COG1131	(ABC) transporter
CD007_04880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CD007_04885	COG1278	Cold shock
CD007_04895	COG1464	Belongs to the NlpA lipoprotein family
CD007_04900	COG3706	GGDEF domain
CD007_04905	COG1823	symporter activity
CD007_04925	COG5577	PFAM Coat F domain
CD007_04930	COG0737	Belongs to the 5'-nucleotidase family
CD007_04930	COG1525	nuclease
CD007_04930	COG4085	toxin activity
CD007_04935	COG3764	Sortase (surface protein transpeptidase)
CD007_04940	COG0564	pseudouridine synthase activity
CD007_04950	COG0517	IMP dehydrogenase activity
CD007_04955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CD007_04960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CD007_04960	COG3153	acetyltransferase
CD007_04965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CD007_04970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CD007_04975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CD007_04980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CD007_04985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CD007_04990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CD007_04995	COG2203	Gaf domain
CD007_04995	COG4585	Histidine kinase
CD007_05000	COG2197	response regulator
CD007_05005	COG0431	NADPH-dependent FMN reductase
CD007_05020	COG1388	LysM domain
CD007_05020	COG0791	NLP P60 protein
CD007_05025	COG1959	2 iron, 2 sulfur cluster binding
CD007_05030	COG0668	transmembrane transport
CD007_05035	COG2719	SpoVR family
CD007_05040	COG1785	Belongs to the alkaline phosphatase family
CD007_05045	COG0791	NLP P60 protein
CD007_05045	COG1388	LysM domain
CD007_05050	COG0583	DNA-binding transcription factor activity
CD007_05055	COG0372	Belongs to the citrate synthase family
CD007_05060	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_05065	COG0531	amino acid
CD007_05070	COG0733	neurotransmitter:sodium symporter activity
CD007_05075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CD007_05080	COG0456	acetyltransferase
CD007_05095	COG1595	DNA-templated transcription, initiation
CD007_05100	COG0667	Aldo Keto reductase
CD007_05105	COG0204	Acyl-transferase
CD007_05110	COG1253	flavin adenine dinucleotide binding
CD007_05115	COG0789	Transcriptional regulator
CD007_05120	COG0436	Aminotransferase
CD007_05125	COG1253	flavin adenine dinucleotide binding
CD007_05130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CD007_05135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CD007_05140	COG0584	glycerophosphoryl diester phosphodiesterase
CD007_05150	COG0668	transmembrane transport
CD007_05155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CD007_05160	COG0726	polysaccharide deacetylase
CD007_05165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CD007_05170	COG1757	Na H antiporter
CD007_05175	COG0589	response to stress
CD007_05185	COG1132	(ABC) transporter
CD007_05190	COG1132	(ABC) transporter
CD007_05195	COG0702	epimerase
CD007_05215	COG0189	ligase activity
CD007_05220	COG0189	ligase activity
CD007_05225	COG4399	Belongs to the UPF0754 family
CD007_05230	COG3679	Belongs to the UPF0342 family
CD007_05235	COG4335	DNA alkylation repair
CD007_05240	COG0561	phosphatase activity
CD007_05245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CD007_05250	COG0475	glutathione-regulated potassium exporter activity
CD007_05255	COG0490	domain, Protein
CD007_05265	COG1024	Enoyl-CoA hydratase
CD007_05275	COG4152	abc transporter atp-binding protein
CD007_05280	COG1668	transmembrane transport
CD007_05285	COG0420	3'-5' exonuclease activity
CD007_05290	COG4717	serine-type aminopeptidase activity
CD007_05295	COG3481	metal-dependent phosphohydrolase, HD sub domain
CD007_05305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CD007_05335	COG1846	Transcriptional regulator
CD007_05340	COG4980	gas vesicle protein
CD007_05355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CD007_05360	COG0537	adenosine 5'-monophosphoramidase activity
CD007_05365	COG1131	(ABC) transporter
CD007_05370	COG4473	ABC transporter
CD007_05380	COG1473	amidohydrolase
CD007_05385	COG3069	C4-dicarboxylate transmembrane transporter activity
CD007_05395	COG2329	Antibiotic biosynthesis monooxygenase
CD007_05400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CD007_05405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CD007_05420	COG1309	transcriptional regulator
CD007_05425	COG1511	domain protein
CD007_05430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CD007_05435	COG4377	Putative membrane peptidase family (DUF2324)
CD007_05445	COG1363	Peptidase, m42
CD007_05450	COG4405	Protein conserved in bacteria
CD007_05455	COG1301	dicarboxylic acid transport
CD007_05465	COG1234	tRNA 3'-trailer cleavage
CD007_05470	COG0095	Lipoate-protein ligase
CD007_05475	COG0702	epimerase
CD007_05480	COG0318	PFAM AMP-dependent synthetase and ligase
CD007_05490	COG0501	Belongs to the peptidase M48B family
CD007_05500	COG0456	acetyltransferase
CD007_05505	COG0604	alcohol dehydrogenase
CD007_05510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CD007_05515	COG0406	alpha-ribazole phosphatase activity
CD007_05520	COG0183	Belongs to the thiolase family
CD007_05525	COG0318	PFAM AMP-dependent synthetase and ligase
CD007_05530	COG1268	BioY protein
CD007_05535	COG0840	transmembrane signaling receptor activity
CD007_05540	COG0723	plastoquinol--plastocyanin reductase activity
CD007_05540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CD007_05545	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_05555	COG4903	ComK protein
CD007_05560	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_05570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CD007_05585	COG0398	Pfam SNARE associated Golgi protein
CD007_05590	COG0681	Belongs to the peptidase S26 family
CD007_05595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CD007_05600	COG1846	Transcriptional regulator
CD007_05615	COG0738	Major facilitator superfamily
CD007_05620	COG0673	inositol 2-dehydrogenase activity
CD007_05625	COG0561	phosphatase activity
CD007_05630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CD007_05635	COG1609	Transcriptional regulator
CD007_05640	COG3180	Ammonia monooxygenase
CD007_05645	COG2814	Major facilitator Superfamily
CD007_05645	COG0477	Major facilitator Superfamily
CD007_05650	COG4533	DNA binding
CD007_05660	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CD007_05665	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CD007_05670	COG1074	ATP-dependent DNA helicase activity
CD007_05675	COG0420	3'-5' exonuclease activity
CD007_05680	COG0419	ATPase involved in DNA repair
CD007_05685	COG1403	HNH endonuclease
CD007_05725	COG5337	Spore coat protein CotH
CD007_05730	COG0179	Fumarylacetoacetate (FAA) hydrolase
CD007_05740	COG1404	Belongs to the peptidase S8 family
CD007_05750	COG0367	asparagine synthase
CD007_05755	COG2318	DinB family
CD007_05760	COG1562	ergosterol biosynthetic process
CD007_05765	COG0534	Mate efflux family protein
CD007_05770	COG2207	Transcriptional regulator
CD007_05770	COG1917	Cupin 2, conserved barrel domain protein
CD007_05775	COG1609	Transcriptional regulator
CD007_05780	COG0673	inositol 2-dehydrogenase activity
CD007_05785	COG2318	DinB family
CD007_05790	COG1279	arginine transmembrane transporter activity
CD007_05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CD007_05800	COG1357	PFAM Pentapeptide repeats (8 copies)
CD007_05805	COG2267	carboxylic ester hydrolase activity
CD007_05810	COG0529	Catalyzes the synthesis of activated sulfate
CD007_05815	COG2046	Belongs to the sulfate adenylyltransferase family
CD007_05820	COG0175	sulfate reduction
CD007_05825	COG2045	Belongs to the ComB family
CD007_05830	COG1809	phosphosulfolactate synthase activity
CD007_05835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CD007_05840	COG4948	Mandelate Racemase Muconate Lactonizing
CD007_05845	COG2814	Major facilitator Superfamily
CD007_05850	COG0454	-acetyltransferase
CD007_05855	COG2153	protein acetylation
CD007_05860	COG0646	methionine synthase
CD007_05860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CD007_05865	COG1666	GTP binding
CD007_05870	COG2996	Protein conserved in bacteria
CD007_05890	COG1695	Transcriptional regulator
CD007_05905	COG3227	Zinc metalloprotease (Elastase)
CD007_05910	COG1307	EDD domain protein, DegV family
CD007_05915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CD007_05930	COG0561	phosphatase activity
CD007_05935	COG1073	alpha beta
CD007_05940	COG2151	metal-sulfur cluster biosynthetic enzyme
CD007_05950	COG0277	FAD linked oxidase domain protein
CD007_05955	COG2271	Major facilitator Superfamily
CD007_05960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CD007_05975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CD007_05980	COG0505	Belongs to the CarA family
CD007_05985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CD007_05990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CD007_06005	COG2267	carboxylic ester hydrolase activity
CD007_06015	COG1744	ABC transporter substrate-binding protein PnrA-like
CD007_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CD007_06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CD007_06040	COG5504	Zn-dependent protease
CD007_06045	COG0444	Belongs to the ABC transporter superfamily
CD007_06050	COG4608	Belongs to the ABC transporter superfamily
CD007_06060	COG0601	transmembrane transport
CD007_06065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CD007_06075	COG0180	Tryptophanyl-tRNA synthetase
CD007_06080	COG4166	transmembrane transport
CD007_06085	COG0601	transmembrane transport
CD007_06090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CD007_06095	COG0444	Belongs to the ABC transporter superfamily
CD007_06100	COG4608	Belongs to the ABC transporter superfamily
CD007_06105	COG2814	Major facilitator Superfamily
CD007_06110	COG0456	acetyltransferase
CD007_06115	COG1393	Belongs to the ArsC family
CD007_06120	COG0861	Integral membrane protein TerC family
CD007_06125	COG4862	establishment of competence for transformation
CD007_06130	COG4469	Competence protein
CD007_06135	COG1164	Oligoendopeptidase f
CD007_06155	COG2346	COG2346, Truncated hemoglobins
CD007_06160	COG0741	lytic transglycosylase activity
CD007_06165	COG4116	CYTH
CD007_06175	COG2357	RelA SpoT domain protein
CD007_06180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CD007_06185	COG0564	pseudouridine synthase activity
CD007_06190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CD007_06195	COG0569	domain protein
CD007_06195	COG0475	glutathione-regulated potassium exporter activity
CD007_06200	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CD007_06205	COG0352	thiamine-phosphate diphosphorylase activity
CD007_06210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CD007_06215	COG2104	thiamine diphosphate biosynthetic process
CD007_06220	COG2022	thiamine diphosphate biosynthetic process
CD007_06225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CD007_06230	COG0351	phosphomethylpyrimidine kinase
CD007_06235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CD007_06290	COG0210	DNA helicase
CD007_06300	COG2153	protein acetylation
CD007_06305	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CD007_06310	COG2382	esterase
CD007_06315	COG0626	cystathionine gamma-synthase activity
CD007_06320	COG0626	cystathionine gamma-synthase activity
CD007_06325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_06330	COG5505	Protein of unknown function (DUF819)
CD007_06365	COG5444	nuclease activity
CD007_06390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CD007_06395	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_06405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_06405	COG3711	transcriptional antiterminator
CD007_06410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_06410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CD007_06410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CD007_06415	COG1482	cell wall glycoprotein biosynthetic process
CD007_06425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_06435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CD007_06455	COG0109	protoheme IX farnesyltransferase activity
CD007_06465	COG0726	polysaccharide deacetylase
CD007_06485	COG2205	protein histidine kinase activity
CD007_06495	COG3383	formate dehydrogenase (NAD+) activity
CD007_06500	COG2427	Protein of unknown function (DUF1641)
CD007_06520	COG2124	cytochrome p450
CD007_06525	COG1819	glycosyl
CD007_06545	COG1587	Uroporphyrinogen-III synthase
CD007_06550	COG0390	transport system, permease component
CD007_06555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CD007_06560	COG0697	spore germination
CD007_06565	COG4297	protein containing double-stranded beta helix domain
CD007_06575	COG1252	NADH dehydrogenase
CD007_06580	COG1904	glucuronate isomerase
CD007_06585	COG2211	Major facilitator Superfamily
CD007_06590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CD007_06595	COG1063	alcohol dehydrogenase
CD007_06600	COG1312	Catalyzes the dehydration of D-mannonate
CD007_06605	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_06610	COG2271	Major facilitator Superfamily
CD007_06615	COG1609	Transcriptional regulator
CD007_06620	COG0246	Mannitol dehydrogenase
CD007_06625	COG2721	sulfolactate sulfo-lyase activity
CD007_06630	COG0730	response to heat
CD007_06635	COG2318	DinB family
CD007_06640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CD007_06645	COG0457	Tetratricopeptide repeat
CD007_06655	COG2350	Protein conserved in bacteria
CD007_06660	COG5632	N-Acetylmuramoyl-L-alanine amidase
CD007_06660	COG3409	Peptidoglycan-binding domain 1 protein
CD007_06660	COG1388	LysM domain
CD007_06670	COG4195	phage-related replication protein
CD007_06675	COG3546	catalase activity
CD007_06680	COG2856	Zn peptidase
CD007_06685	COG1396	sequence-specific DNA binding
CD007_06695	COG1522	sequence-specific DNA binding
CD007_06700	COG1484	DNA-dependent DNA replication
CD007_06720	COG1595	DNA-templated transcription, initiation
CD007_06725	COG5484	DNA packaging
CD007_06725	COG3728	DNA packaging
CD007_06730	COG1783	phage Terminase large subunit
CD007_06735	COG5518	Phage portal protein
CD007_06740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CD007_06745	COG4653	Phage capsid family
CD007_06795	COG5412	phage tail tape measure protein
CD007_06795	COG3953	SLT domain
CD007_06800	COG1652	LysM domain
CD007_06805	COG4193	domain, Protein
CD007_06815	COG3628	GPW Gp25 family protein
CD007_06820	COG3299	homolog of phage Mu protein gp47
CD007_06825	COG3778	Protein conserved in bacteria
CD007_06865	COG3409	Peptidoglycan-binding domain 1 protein
CD007_06865	COG5632	N-Acetylmuramoyl-L-alanine amidase
CD007_06880	COG0306	phosphate transporter
CD007_06885	COG1392	Phosphate transport regulator
CD007_06890	COG0531	amino acid
CD007_06895	COG0346	lactoylglutathione lyase activity
CD007_06900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CD007_06905	COG0463	Glycosyl transferase, family 2
CD007_06910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CD007_06915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CD007_06920	COG2362	D-Aminopeptidase
CD007_06925	COG0601	transmembrane transport
CD007_06930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CD007_06935	COG0444	Belongs to the ABC transporter superfamily
CD007_06940	COG4166	transmembrane transport
CD007_06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
CD007_06950	COG4948	Mandelate Racemase Muconate Lactonizing
CD007_06955	COG0791	NLP P60 protein
CD007_06960	COG4608	Belongs to the ABC transporter superfamily
CD007_06965	COG2706	6-phosphogluconolactonase activity
CD007_06970	COG1834	amidinotransferase
CD007_06975	COG1607	acyl-coa hydrolase
CD007_06980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CD007_06980	COG1017	nitric oxide dioxygenase activity
CD007_06990	COG2323	membrane
CD007_06995	COG2318	DinB family
CD007_07000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_07005	COG2076	Multidrug Resistance protein
CD007_07010	COG2076	Multidrug Resistance protein
CD007_07015	COG0788	formyltetrahydrofolate deformylase activity
CD007_07020	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CD007_07025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CD007_07030	COG1764	response to oxidative stress
CD007_07035	COG1846	Transcriptional regulator
CD007_07040	COG1764	response to oxidative stress
CD007_07050	COG0590	tRNA wobble adenosine to inosine editing
CD007_07055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CD007_07060	COG1404	Belongs to the peptidase S8 family
CD007_07065	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_07070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CD007_07075	COG1122	ATPase activity
CD007_07080	COG4721	ABC-type cobalt transport system, permease component
CD007_07090	COG0745	RESPONSE REGULATOR receiver
CD007_07095	COG3850	Histidine kinase
CD007_07095	COG5002	protein histidine kinase activity
CD007_07100	COG3212	peptidase
CD007_07105	COG3212	peptidase
CD007_07120	COG2239	Acts as a magnesium transporter
CD007_07125	COG0789	Transcriptional regulator
CD007_07140	COG1846	Transcriptional regulator
CD007_07145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CD007_07150	COG0726	polysaccharide deacetylase
CD007_07155	COG1408	metallophosphoesterase
CD007_07165	COG0463	Glycosyl transferase, family 2
CD007_07170	COG1793	dna ligase
CD007_07170	COG3285	dna ligase
CD007_07175	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CD007_07180	COG3300	MHYT domain
CD007_07180	COG5001	Diguanylate cyclase
CD007_07185	COG0586	Pfam SNARE associated Golgi protein
CD007_07190	COG0861	Integral membrane protein TerC family
CD007_07195	COG1191	sigma factor activity
CD007_07215	COG0501	Belongs to the peptidase M48B family
CD007_07220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CD007_07235	COG3594	Acyltransferase
CD007_07240	COG5002	protein histidine kinase activity
CD007_07245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CD007_07250	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CD007_07255	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CD007_07260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CD007_07265	COG0436	Aminotransferase
CD007_07270	COG1850	ribulose-bisphosphate carboxylase activity
CD007_07275	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CD007_07280	COG0235	Class ii aldolase
CD007_07285	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CD007_07290	COG3339	Conserved Protein
CD007_07305	COG3852	Histidine kinase
CD007_07310	COG1846	Transcriptional regulator
CD007_07315	COG1360	Flagellar Motor Protein
CD007_07320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CD007_07330	COG0542	response to heat
CD007_07335	COG3949	Membrane
CD007_07340	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CD007_07345	COG0720	synthase
CD007_07350	COG0602	queuosine metabolic process
CD007_07355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CD007_07360	COG1733	regulation of RNA biosynthetic process
CD007_07365	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_07370	COG1388	LysM domain
CD007_07370	COG4641	Protein conserved in bacteria
CD007_07375	COG1388	LysM domain
CD007_07380	COG3858	chitin binding
CD007_07385	COG3858	chitin binding
CD007_07395	COG4873	Protein conserved in bacteria
CD007_07405	COG3773	Cell wall hydrolase
CD007_07410	COG2244	polysaccharide biosynthetic process
CD007_07415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_07420	COG2217	Heavy metal translocating P-type atpase
CD007_07430	COG0006	proline dipeptidase activity
CD007_07435	COG1609	Transcriptional regulator
CD007_07440	COG3711	transcriptional antiterminator
CD007_07445	COG2190	(PTS) system
CD007_07445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_07445	COG1263	PTS System
CD007_07450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_07455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CD007_07465	COG1533	DNA photolyase activity
CD007_07470	COG0456	acetyltransferase
CD007_07475	COG0840	transmembrane signaling receptor activity
CD007_07480	COG2084	Dehydrogenase
CD007_07485	COG2340	Cysteine-rich secretory protein family
CD007_07490	COG0768	penicillin binding
CD007_07495	COG4191	Histidine kinase
CD007_07500	COG0436	Aminotransferase
CD007_07510	COG0784	Response regulator, receiver
CD007_07510	COG0835	chemotaxis
CD007_07520	COG2814	Major facilitator Superfamily
CD007_07525	COG1376	ErfK ybiS ycfS ynhG family protein
CD007_07530	COG1408	metallophosphoesterase
CD007_07535	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_07540	COG2200	EAL domain
CD007_07545	COG4703	Protein of unknown function (DUF1797)
CD007_07550	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CD007_07560	COG0517	IMP dehydrogenase activity
CD007_07565	COG0583	DNA-binding transcription factor activity
CD007_07570	COG0716	FMN binding
CD007_07580	COG0716	FMN binding
CD007_07585	COG2171	N-acyltransferase activity
CD007_07590	COG1473	amidohydrolase
CD007_07600	COG0668	transmembrane transport
CD007_07605	COG0450	alkyl hydroperoxide reductase
CD007_07610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_07625	COG0746	molybdenum cofactor guanylyltransferase activity
CD007_07630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CD007_07635	COG0303	'Molybdopterin
CD007_07640	COG1763	Mo-molybdopterin cofactor biosynthetic process
CD007_07645	COG0314	molybdopterin synthase activity
CD007_07650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CD007_07655	COG1132	(ABC) transporter
CD007_07660	COG1132	(ABC) transporter
CD007_07670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CD007_07675	COG1136	(ABC) transporter
CD007_07680	COG0577	efflux transmembrane transporter activity
CD007_07685	COG1349	DNA-binding transcription factor activity
CD007_07690	COG1105	Belongs to the carbohydrate kinase PfkB family
CD007_07695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CD007_07695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CD007_07695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_07700	COG0681	Belongs to the peptidase S26 family
CD007_07710	COG0488	(ABC) transporter
CD007_07715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CD007_07720	COG2309	aminopeptidase activity
CD007_07730	COG1077	Cell shape determining protein MreB Mrl
CD007_07735	COG2002	toxin-antitoxin pair type II binding
CD007_07740	COG3852	Histidine kinase
CD007_07745	COG2105	PFAM AIG2 family protein
CD007_07745	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CD007_07750	COG0569	domain protein
CD007_07755	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CD007_07760	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CD007_07770	COG0561	phosphatase activity
CD007_07775	COG0242	peptide deformylase activity
CD007_07785	COG0497	DNA recombination
CD007_07790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CD007_07795	COG0022	dehydrogenase e1 component
CD007_07800	COG0508	dehydrogenase complex catalyzes the overall conversion of
CD007_07805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CD007_07810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_07820	COG1982	Orn Lys Arg decarboxylase major
CD007_07825	COG4476	Belongs to the UPF0223 family
CD007_07830	COG4493	Belongs to the UPF0637 family
CD007_07840	COG0483	inositol monophosphate 1-phosphatase activity
CD007_07850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CD007_07905	COG4896	Protein conserved in bacteria
CD007_07915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CD007_07920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CD007_07925	COG2066	Belongs to the glutaminase family
CD007_07930	COG4838	Belongs to the UPF0358 family
CD007_07935	COG0772	Belongs to the SEDS family
CD007_07940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CD007_07945	COG1612	heme a metabolic process
CD007_07950	COG0109	protoheme IX farnesyltransferase activity
CD007_07955	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CD007_07955	COG2010	Cytochrome c
CD007_07960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CD007_07965	COG1845	cytochrome c oxidase, subunit III
CD007_07970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CD007_07975	COG3336	cytochrome c oxidase
CD007_07985	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CD007_07990	COG2340	Cysteine-rich secretory protein family
CD007_08005	COG3679	Belongs to the UPF0342 family
CD007_08010	COG4471	UPF0298 protein
CD007_08015	COG0742	ribosomal rna small subunit methyltransferase
CD007_08020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CD007_08025	COG3314	Sporulation integral membrane protein YlbJ
CD007_08030	COG1752	Esterase of the alpha-beta hydrolase superfamily
CD007_08035	COG3480	Lon protease (S16) C-terminal proteolytic domain
CD007_08040	COG1323	Belongs to the UPF0348 family
CD007_08050	COG1399	metal-binding, possibly nucleic acid-binding protein
CD007_08055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CD007_08065	COG0454	-acetyltransferase
CD007_08070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CD007_08075	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CD007_08080	COG2001	Belongs to the MraZ family
CD007_08085	COG0275	rRNA processing
CD007_08090	COG4839	cell division protein FtsL
CD007_08100	COG0768	penicillin binding
CD007_08105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CD007_08110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CD007_08115	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CD007_08120	COG0772	Belongs to the SEDS family
CD007_08125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CD007_08130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CD007_08135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CD007_08140	COG3879	Bacterial protein of unknown function (DUF881)
CD007_08145	COG3879	Bacterial protein of unknown function (DUF881)
CD007_08150	COG3856	small basic protein
CD007_08155	COG0849	cell division
CD007_08160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CD007_08165	COG4412	M6 family metalloprotease domain protein
CD007_08165	COG1404	Belongs to the peptidase S8 family
CD007_08175	COG1191	sigma factor activity
CD007_08180	COG1191	sigma factor activity
CD007_08185	COG1119	ATPase activity
CD007_08190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CD007_08195	COG1873	PFAM PRC-barrel domain
CD007_08205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CD007_08210	COG1799	cell septum assembly
CD007_08215	COG0762	integral membrane protein
CD007_08220	COG2302	S4 RNA-binding domain
CD007_08225	COG3599	regulation of cell shape
CD007_08230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CD007_08235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CD007_08240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CD007_08245	COG0564	pseudouridine synthase activity
CD007_08250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CD007_08255	COG2233	PERMEase
CD007_08260	COG0540	Belongs to the ATCase OTCase family
CD007_08265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CD007_08270	COG0505	Belongs to the CarA family
CD007_08275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CD007_08280	COG0543	2 iron, 2 sulfur cluster binding
CD007_08285	COG0167	dihydroorotate dehydrogenase activity
CD007_08290	COG0284	orotidine-5'-phosphate decarboxylase activity
CD007_08295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CD007_08300	COG0175	sulfate reduction
CD007_08305	COG0306	phosphate transporter
CD007_08310	COG2046	Belongs to the sulfate adenylyltransferase family
CD007_08315	COG0529	Catalyzes the synthesis of activated sulfate
CD007_08320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CD007_08325	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CD007_08330	COG1648	precorrin-2 dehydrogenase activity
CD007_08340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CD007_08345	COG1561	YicC-like family, N-terminal region
CD007_08350	COG2052	Domain of unknown function (DUF370)
CD007_08355	COG0194	GDP metabolic process
CD007_08360	COG1758	RNA polymerase activity
CD007_08365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CD007_08370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CD007_08375	COG0242	peptide deformylase activity
CD007_08380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CD007_08385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CD007_08385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CD007_08390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CD007_08395	COG0631	protein serine/threonine phosphatase activity
CD007_08400	COG0515	serine threonine protein kinase
CD007_08400	COG2815	serine threonine protein kinase
CD007_08405	COG1162	GTPase activity
CD007_08410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CD007_08415	COG1564	THIamine pyrophosphokinase
CD007_08425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CD007_08430	COG1302	Protein conserved in bacteria
CD007_08435	COG1461	Dihydroxyacetone kinase
CD007_08440	COG1760	l-serine dehydratase
CD007_08445	COG1760	l-serine dehydratase
CD007_08450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CD007_08455	COG2050	protein possibly involved in aromatic compounds catabolism
CD007_08455	COG1349	DNA-binding transcription factor activity
CD007_08460	COG0416	fatty acid biosynthetic process
CD007_08465	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CD007_08470	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_08475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CD007_08480	COG0571	ribonuclease III activity
CD007_08485	COG1196	nuclear chromosome segregation
CD007_08490	COG0552	protein localization to endoplasmic reticulum
CD007_08500	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CD007_08505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CD007_08510	COG0228	four-way junction DNA binding
CD007_08515	COG1837	Belongs to the UPF0109 family
CD007_08525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CD007_08530	COG0336	Belongs to the RNA methyltransferase TrmD family
CD007_08535	COG0335	large ribosomal subunit rRNA binding
CD007_08540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CD007_08545	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CD007_08555	COG2257	FlhB HrpN YscU SpaS Family
CD007_08560	COG0045	succinate-CoA ligase (ADP-forming) activity
CD007_08565	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CD007_08570	COG0758	DNA mediated transformation
CD007_08575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CD007_08580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CD007_08585	COG4974	Belongs to the 'phage' integrase family
CD007_08590	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CD007_08595	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CD007_08600	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CD007_08605	COG1815	bacterial-type flagellum-dependent cell motility
CD007_08610	COG1558	bacterial-type flagellum-dependent cell motility
CD007_08615	COG1677	Flagellar hook-basal body complex protein FliE
CD007_08620	COG1766	The M ring may be actively involved in energy transduction
CD007_08625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CD007_08630	COG1317	bacterial-type flagellum organization
CD007_08635	COG1157	protein secretion by the type III secretion system
CD007_08640	COG2882	bacterial-type flagellum organization
CD007_08645	COG3334	PFAM MgtE intracellular
CD007_08650	COG3144	bacterial-type flagellum assembly
CD007_08655	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CD007_08660	COG4786	Flagellar basal body rod
CD007_08665	COG1582	Flagellar protein (FlbD)
CD007_08670	COG1580	Controls the rotational direction of flagella during chemotaxis
CD007_08675	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CD007_08680	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CD007_08680	COG1776	CheC inhibitor of MCP methylation
CD007_08685	COG2201	protein-glutamate methylesterase activity
CD007_08690	COG3190	flagellar
CD007_08695	COG1338	Plays a role in the flagellum-specific transport system
CD007_08700	COG1987	bacterial-type flagellum assembly
CD007_08705	COG1684	flagellar biosynthetic protein fliR
CD007_08710	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CD007_08715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CD007_08720	COG1419	protein localization to endoplasmic reticulum
CD007_08725	COG0455	bacterial-type flagellum organization
CD007_08730	COG2201	protein-glutamate methylesterase activity
CD007_08735	COG0643	Histidine kinase
CD007_08735	COG2198	Histidine kinase
CD007_08740	COG0835	chemotaxis
CD007_08745	COG1776	CheC inhibitor of MCP methylation
CD007_08750	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CD007_08755	COG1191	sigma factor activity
CD007_08765	COG0052	Belongs to the universal ribosomal protein uS2 family
CD007_08770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CD007_08775	COG0528	UMP kinase activity
CD007_08780	COG0233	cytoplasmic translational termination
CD007_08785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CD007_08790	COG4589	Belongs to the CDS family
CD007_08795	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CD007_08800	COG0750	zinc metalloprotease
CD007_08805	COG0442	prolyl-tRNA aminoacylation
CD007_08810	COG2176	DNA-directed DNA polymerase activity
CD007_08835	COG0779	Required for maturation of 30S ribosomal subunits
CD007_08840	COG0195	Participates in both transcription termination and antitermination
CD007_08845	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CD007_08850	COG1358	cellular component organization or biogenesis
CD007_08855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CD007_08860	COG1550	Protein conserved in bacteria
CD007_08865	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CD007_08870	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CD007_08875	COG0196	riboflavin kinase activity
CD007_08880	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CD007_08885	COG1185	polyribonucleotide nucleotidyltransferase activity
CD007_08890	COG0726	polysaccharide deacetylase
CD007_08895	COG0612	Peptidase, M16
CD007_08900	COG1873	PFAM PRC-barrel domain
CD007_08905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CD007_08910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CD007_08915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CD007_08920	COG0527	aspartate kinase activity
CD007_08925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CD007_08930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CD007_08935	COG0740	serine-type endopeptidase activity
CD007_08945	COG1674	ftsk spoiiie
CD007_08945	COG4980	gas vesicle protein
CD007_08950	COG2188	Transcriptional regulator
CD007_08955	COG2814	Major facilitator Superfamily
CD007_08960	COG0612	Peptidase, M16
CD007_08965	COG0612	Peptidase, M16
CD007_08970	COG0300	oxidoreductase activity
CD007_08985	COG1426	Protein conserved in bacteria
CD007_08990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CD007_08995	COG1058	Belongs to the CinA family
CD007_08995	COG1546	Belongs to the CinA family
CD007_09000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CD007_09005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CD007_09010	COG1418	mRNA catabolic process
CD007_09015	COG1692	metallophosphoesterase
CD007_09020	COG2359	stage V sporulation protein S
CD007_09025	COG1063	alcohol dehydrogenase
CD007_09030	COG0156	8-amino-7-oxononanoate synthase activity
CD007_09035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CD007_09040	COG4550	Control of competence regulator ComK, YlbF/YmcA
CD007_09050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CD007_09055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CD007_09070	COG3226	Transcriptional regulator
CD007_09075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_09085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CD007_09090	COG3321	synthase
CD007_09095	COG2070	2-Nitropropane dioxygenase
CD007_09095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CD007_09100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CD007_09105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CD007_09110	COG3425	synthase
CD007_09115	COG1024	Enoyl-CoA hydratase
CD007_09120	COG1024	Enoyl-CoA hydratase
CD007_09125	COG3321	synthase
CD007_09125	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_09125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09125	COG0318	PFAM AMP-dependent synthetase and ligase
CD007_09125	COG0300	oxidoreductase activity
CD007_09130	COG3321	synthase
CD007_09130	COG0300	oxidoreductase activity
CD007_09130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CD007_09130	COG4221	oxidoreductase activity
CD007_09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CD007_09135	COG3321	synthase
CD007_09135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CD007_09135	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_09135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09140	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_09140	COG3321	synthase
CD007_09140	COG4221	oxidoreductase activity
CD007_09145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CD007_09145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CD007_09145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CD007_09145	COG3321	synthase
CD007_09150	COG2124	cytochrome p450
CD007_09160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_09165	COG1404	Belongs to the peptidase S8 family
CD007_09175	COG4195	phage-related replication protein
CD007_09180	COG1764	response to oxidative stress
CD007_09185	COG2076	Multidrug Resistance protein
CD007_09190	COG2076	Multidrug Resistance protein
CD007_09205	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CD007_09210	COG1923	regulation of RNA biosynthetic process
CD007_09225	COG1780	Probably involved in ribonucleotide reductase function
CD007_09230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CD007_09235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CD007_09240	COG4112	unkown
CD007_09245	COG0860	N-Acetylmuramoyl-L-alanine amidase
CD007_09255	COG0464	growth
CD007_09260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CD007_09265	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CD007_09270	COG0789	Transcriptional regulator
CD007_09275	COG0174	glutamine synthetase
CD007_09300	COG4282	regulation of fungal-type cell wall biogenesis
CD007_09310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_09340	COG0135	phosphoribosylanthranilate isomerase activity
CD007_09345	COG2211	Major facilitator Superfamily
CD007_09350	COG3507	Belongs to the glycosyl hydrolase 43 family
CD007_09355	COG1940	carbohydrate kinase activity
CD007_09360	COG2115	Belongs to the xylose isomerase family
CD007_09365	COG1070	Carbohydrate kinase
CD007_09380	COG2814	Major facilitator Superfamily
CD007_09385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CD007_09400	COG0756	dUTP diphosphatase activity
CD007_09435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CD007_09445	COG3832	glyoxalase III activity
CD007_09455	COG0697	spore germination
CD007_09460	COG0531	amino acid
CD007_09490	COG4195	phage-related replication protein
CD007_09500	COG0346	lactoylglutathione lyase activity
CD007_09510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CD007_09515	COG1388	LysM domain
CD007_09520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CD007_09525	COG4224	UPF0291 protein
CD007_09530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CD007_09540	COG3763	UPF0154 protein
CD007_09550	COG0785	Cytochrome C biogenesis protein
CD007_09555	COG2201	protein-glutamate methylesterase activity
CD007_09560	COG4846	Membrane protein involved in cytochrome C biogenesis
CD007_09570	COG0071	Belongs to the small heat shock protein (HSP20) family
CD007_09585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CD007_09590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_09610	COG0824	Thioesterase
CD007_09620	COG4841	protein insertion into membrane
CD007_09625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CD007_09630	COG1832	CoA-binding protein
CD007_09635	COG0187	DNA topoisomerase II activity
CD007_09640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CD007_09650	COG1115	amino acid carrier protein
CD007_09655	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CD007_09665	COG5520	Belongs to the glycosyl hydrolase 30 family
CD007_09670	COG3507	Belongs to the glycosyl hydrolase 43 family
CD007_09675	COG2246	polysaccharide biosynthetic process
CD007_09680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CD007_09685	COG0586	Pfam SNARE associated Golgi protein
CD007_09690	COG2404	hydrolase activity, acting on ester bonds
CD007_09695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CD007_09700	COG1024	Enoyl-CoA hydratase
CD007_09705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CD007_09710	COG0511	ligase activity, forming carbon-carbon bonds
CD007_09715	COG0439	Biotin carboxylase
CD007_09720	COG0318	PFAM AMP-dependent synthetase and ligase
CD007_09725	COG1960	acyl-CoA dehydrogenase activity
CD007_09735	COG1649	PFAM Uncharacterised BCR, COG1649
CD007_09745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CD007_09750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_09770	COG2027	D-alanyl-D-alanine carboxypeptidase
CD007_09775	COG2017	converts alpha-aldose to the beta-anomer
CD007_09780	COG0534	Mate efflux family protein
CD007_09795	COG0582	viral genome integration into host DNA
CD007_09800	COG0166	Belongs to the GPI family
CD007_09805	COG0405	Gamma-glutamyltransferase
CD007_09810	COG0583	DNA-binding transcription factor activity
CD007_09820	COG0493	'glutamate synthase
CD007_09825	COG0070	glutamate synthase
CD007_09825	COG0069	glutamate synthase activity
CD007_09825	COG0067	glutamate synthase
CD007_09830	COG0583	DNA-binding transcription factor activity
CD007_09835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CD007_09840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CD007_09850	COG0300	oxidoreductase activity
CD007_09855	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CD007_09865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CD007_09880	COG1131	(ABC) transporter
CD007_09890	COG2814	Major facilitator Superfamily
CD007_09895	COG1070	Carbohydrate kinase
CD007_09900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CD007_09905	COG0243	molybdopterin cofactor binding
CD007_09915	COG2814	Major facilitator Superfamily
CD007_09920	COG0673	inositol 2-dehydrogenase activity
CD007_09925	COG1082	Xylose isomerase domain protein TIM barrel
CD007_09930	COG1609	Transcriptional regulator
CD007_09950	COG5278	phosphoserine phosphatase activity
CD007_09950	COG0840	transmembrane signaling receptor activity
CD007_09955	COG2368	4-hydroxyphenylacetate
CD007_09960	COG4305	rare lipoprotein A
CD007_09965	COG3619	membrane
CD007_09970	COG3866	Pectate lyase
CD007_09975	COG2135	peptidase activity
CD007_09985	COG2140	Oxalate decarboxylase
CD007_10005	COG2720	vancomycin resistance protein
CD007_10020	COG3739	integral membrane protein
CD007_10025	COG0583	DNA-binding transcription factor activity
CD007_10030	COG0697	spore germination
CD007_10040	COG0693	protein deglycase activity
CD007_10045	COG2367	Beta-lactamase
CD007_10070	COG3848	Pyruvate phosphate dikinase
CD007_10070	COG0574	Belongs to the PEP-utilizing enzyme family
CD007_10075	COG0726	polysaccharide deacetylase
CD007_10085	COG2314	TM2 domain
CD007_10115	COG3655	Transcriptional regulator
CD007_10160	COG0457	Tetratricopeptide repeat
CD007_10170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CD007_10180	COG4282	regulation of fungal-type cell wall biogenesis
CD007_10185	COG1231	oxidoreductase activity
CD007_10190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CD007_10195	COG2207	Transcriptional regulator
CD007_10195	COG0662	Cupin 2, conserved barrel domain protein
CD007_10200	COG0456	acetyltransferase
CD007_10205	COG1309	transcriptional regulator
CD007_10210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_10215	COG3708	Transcriptional regulator
CD007_10220	COG2378	regulation of single-species biofilm formation
CD007_10230	COG0640	Transcriptional regulator
CD007_10235	COG0741	lytic transglycosylase activity
CD007_10240	COG2322	membrane
CD007_10255	COG1619	proteins homologs of microcin C7 resistance protein MccF
CD007_10260	COG3239	Fatty acid desaturase
CD007_10265	COG4585	Histidine kinase
CD007_10270	COG2197	response regulator
CD007_10275	COG3584	3D domain protein
CD007_10275	COG1388	LysM domain
CD007_10280	COG0514	ATP-dependent DNA helicase (RecQ)
CD007_10295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CD007_10300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CD007_10315	COG0071	Belongs to the small heat shock protein (HSP20) family
CD007_10340	COG1012	belongs to the aldehyde dehydrogenase family
CD007_10345	COG1657	PFAM Prenyltransferase squalene oxidase
CD007_10350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CD007_10355	COG0733	neurotransmitter:sodium symporter activity
CD007_10360	COG0385	Bile acid
CD007_10365	COG0508	dehydrogenase complex catalyzes the overall conversion of
CD007_10370	COG0567	Dehydrogenase, E1 component
CD007_10375	COG4548	von Willebrand factor, type A
CD007_10380	COG0714	Associated with various cellular activities
CD007_10385	COG2032	superoxide dismutase activity
CD007_10390	COG0791	NLP P60 protein
CD007_10390	COG1388	LysM domain
CD007_10395	COG1819	glycosyl
CD007_10400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CD007_10405	COG0534	Mate efflux family protein
CD007_10410	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_10415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CD007_10420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CD007_10430	COG2962	Rard protein
CD007_10445	COG2610	gluconate transmembrane transporter activity
CD007_10450	COG1942	4-Oxalocrotonate Tautomerase
CD007_10455	COG1733	regulation of RNA biosynthetic process
CD007_10460	COG0778	Nitroreductase
CD007_10465	COG0400	carboxylic ester hydrolase activity
CD007_10470	COG0346	lactoylglutathione lyase activity
CD007_10480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CD007_10485	COG3409	Peptidoglycan-binding domain 1 protein
CD007_10485	COG0793	Belongs to the peptidase S41A family
CD007_10490	COG2226	methyltransferase
CD007_10500	COG1876	peptidase activity
CD007_10505	COG0813	purine-nucleoside phosphorylase activity
CD007_10520	COG0671	phosphoesterase, PA-phosphatase related
CD007_10540	COG4479	Belongs to the UPF0346 family
CD007_10550	COG1509	lysine 2,3-aminomutase activity
CD007_10555	COG0456	acetyltransferase
CD007_10560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CD007_10565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CD007_10570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CD007_10575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CD007_10585	COG0456	acetyltransferase
CD007_10590	COG0463	Glycosyl transferase, family 2
CD007_10605	COG4641	Protein conserved in bacteria
CD007_10610	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CD007_10615	COG1086	Polysaccharide biosynthesis protein
CD007_10620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CD007_10625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CD007_10630	COG1846	Transcriptional regulator
CD007_10635	COG0534	Mate efflux family protein
CD007_10645	COG4698	Protein conserved in bacteria
CD007_10650	COG2755	lipolytic protein G-D-S-L family
CD007_10655	COG1999	signal sequence binding
CD007_10665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CD007_10670	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CD007_10675	COG1272	protein, Hemolysin III
CD007_10680	COG0204	Acyl-transferase
CD007_10685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CD007_10690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CD007_10700	COG2136	Putative SAM-dependent methyltransferase
CD007_10700	COG2521	methyltransferase
CD007_10710	COG0129	dihydroxy-acid dehydratase activity
CD007_10715	COG1413	lyase activity
CD007_10720	COG1418	mRNA catabolic process
CD007_10725	COG0386	Belongs to the glutathione peroxidase family
CD007_10730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CD007_10735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CD007_10740	COG1278	Cold shock
CD007_10760	COG0328	RNA-DNA hybrid ribonuclease activity
CD007_10765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CD007_10770	COG0328	RNA-DNA hybrid ribonuclease activity
CD007_10780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CD007_10795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CD007_10800	COG1755	Isoprenylcysteine carboxyl methyltransferase
CD007_10805	COG3424	synthase
CD007_10810	COG2233	PERMEase
CD007_10815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CD007_10820	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CD007_10830	COG0800	Aldolase
CD007_10835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CD007_10840	COG1609	Transcriptional regulator
CD007_10845	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CD007_10850	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_10855	COG1199	ATP-dependent helicase activity
CD007_10870	COG0116	Belongs to the methyltransferase superfamily
CD007_10885	COG4474	Belongs to the UPF0398 family
CD007_10895	COG3359	exonuclease
CD007_10900	COG1111	helicase
CD007_10900	COG1205	dead DEAH box helicase
CD007_10905	COG2190	(PTS) system
CD007_10910	COG0071	Belongs to the small heat shock protein (HSP20) family
CD007_10945	COG3331	DNA recombination
CD007_10950	COG4499	WXG100 protein secretion system (Wss), protein YukC
CD007_10950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CD007_10960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CD007_10965	COG3935	DnaD domain protein
CD007_10970	COG0017	Asparaginyl-tRNA synthetase
CD007_10975	COG0436	Aminotransferase
CD007_10980	COG5353	protein conserved in bacteria
CD007_10990	COG1199	ATP-dependent helicase activity
CD007_10990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CD007_10995	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CD007_11000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CD007_11005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CD007_11010	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CD007_11010	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CD007_11015	COG0617	tRNA 3'-terminal CCA addition
CD007_11020	COG0438	transferase activity, transferring glycosyl groups
CD007_11025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CD007_11030	COG1803	Methylglyoxal synthase
CD007_11035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CD007_11040	COG1694	Mazg nucleotide pyrophosphohydrolase
CD007_11045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CD007_11055	COG4347	Protein of unknown function (DUF1405)
CD007_11060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CD007_11060	COG2010	Cytochrome c
CD007_11065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CD007_11070	COG0723	plastoquinol--plastocyanin reductase activity
CD007_11080	COG5582	Belongs to the UPF0302 family
CD007_11085	COG0457	Tetratricopeptide repeat
CD007_11090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CD007_11095	COG0287	Prephenate dehydrogenase
CD007_11100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CD007_11110	COG0133	tryptophan synthase activity
CD007_11115	COG0135	phosphoribosylanthranilate isomerase activity
CD007_11125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CD007_11130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CD007_11135	COG4401	Chorismate mutase type I
CD007_11140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CD007_11145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CD007_11150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CD007_11155	COG0105	UTP biosynthetic process
CD007_11160	COG0142	geranyltranstransferase activity
CD007_11165	COG2226	methyltransferase
CD007_11170	COG0142	geranyltranstransferase activity
CD007_11180	COG0302	gtp cyclohydrolase
CD007_11185	COG0776	regulation of translation
CD007_11190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CD007_11205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CD007_11210	COG1160	GTP binding
CD007_11235	COG1304	FMN binding
CD007_11240	COG0539	negative regulation of cytoplasmic translation
CD007_11245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CD007_11255	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CD007_11260	COG2959	enzyme of heme biosynthesis
CD007_11265	COG3773	Cell wall hydrolase
CD007_11265	COG3409	Peptidoglycan-binding domain 1 protein
CD007_11270	COG2339	peptidase activity
CD007_11275	COG0492	ferredoxin-NADP+ reductase activity
CD007_11280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CD007_11285	COG4862	establishment of competence for transformation
CD007_11290	COG1408	metallophosphoesterase
CD007_11300	COG1388	LysM domain
CD007_11305	COG1266	CAAX protease self-immunity
CD007_11310	COG0514	ATP-dependent DNA helicase (RecQ)
CD007_11315	COG4955	Helix-turn-helix domain
CD007_11320	COG1141	Ferredoxin
CD007_11325	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CD007_11330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CD007_11335	COG0710	3-dehydroquinate dehydratase activity
CD007_11345	COG1595	DNA-templated transcription, initiation
CD007_11350	COG5002	protein histidine kinase activity
CD007_11355	COG0745	RESPONSE REGULATOR receiver
CD007_11360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CD007_11365	COG1333	cytochrome c biogenesis protein
CD007_11370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_11375	COG1187	pseudouridine synthase activity
CD007_11380	COG0700	Nucleoside recognition
CD007_11385	COG2715	membrane protein required for spore maturation
CD007_11390	COG1686	Belongs to the peptidase S11 family
CD007_11400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CD007_11405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CD007_11410	COG1547	Domain of unknown function (DUF309)
CD007_11415	COG0456	acetyltransferase
CD007_11420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CD007_11425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CD007_11425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CD007_11430	COG0307	riboflavin synthase, alpha
CD007_11435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CD007_11435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CD007_11445	COG0681	Belongs to the peptidase S26 family
CD007_11465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CD007_11475	COG4086	secreted protein
CD007_11480	COG0019	diaminopimelate decarboxylase activity
CD007_11485	COG0697	spore germination
CD007_11500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CD007_11520	COG1191	sigma factor activity
CD007_11525	COG2172	sigma factor antagonist activity
CD007_11530	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_11535	COG1686	Belongs to the peptidase S11 family
CD007_11540	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CD007_11545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CD007_11550	COG4974	Belongs to the 'phage' integrase family
CD007_11560	COG0735	belongs to the Fur family
CD007_11565	COG1300	Membrane
CD007_11575	COG0281	malic enzyme
CD007_11580	COG1757	Na H antiporter
CD007_11585	COG1027	Aspartate ammonia-lyase
CD007_11590	COG0252	asparaginase activity
CD007_11595	COG1396	sequence-specific DNA binding
CD007_11600	COG1379	DNA repair
CD007_11605	COG0494	nUDIX hydrolase
CD007_11615	COG0667	Aldo Keto reductase
CD007_11625	COG1073	alpha beta
CD007_11635	COG4918	Iron-sulphur cluster biosynthesis
CD007_11640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CD007_11640	COG0456	acetyltransferase
CD007_11645	COG2329	Antibiotic biosynthesis monooxygenase
CD007_11650	COG0456	acetyltransferase
CD007_11660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CD007_11670	COG2211	Major facilitator Superfamily
CD007_11680	COG0346	lactoylglutathione lyase activity
CD007_11685	COG1072	(Pantothenic acid kinase))
CD007_11690	COG3048	D-serine ammonia-lyase activity
CD007_11695	COG0300	oxidoreductase activity
CD007_11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_11705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CD007_11710	COG4187	Peptidase family M20/M25/M40
CD007_11715	COG1902	pentaerythritol trinitrate reductase activity
CD007_11720	COG0596	Alpha beta hydrolase
CD007_11730	COG1234	tRNA 3'-trailer cleavage
CD007_11735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CD007_11740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CD007_11745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CD007_11755	COG0706	membrane insertase activity
CD007_11760	COG3361	conserved protein (COG2071)
CD007_11765	COG2195	Cleaves the N-terminal amino acid of tripeptides
CD007_11770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CD007_11775	COG0346	lactoylglutathione lyase activity
CD007_11780	COG1376	ErfK ybiS ycfS ynhG family protein
CD007_11785	COG4129	membrane
CD007_11790	COG1126	abc transporter atp-binding protein
CD007_11795	COG0765	amino acid transport
CD007_11800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CD007_11810	COG1597	lipid kinase activity
CD007_11815	COG2814	Major facilitator Superfamily
CD007_11820	COG0789	Transcriptional regulator
CD007_11820	COG4978	Transcriptional regulator
CD007_11825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CD007_11830	COG0022	dehydrogenase e1 component
CD007_11835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CD007_11840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CD007_11845	COG3426	butyrate kinase activity
CD007_11850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CD007_11855	COG0280	phosphate acetyltransferase
CD007_11860	COG3290	protein histidine kinase activity
CD007_11860	COG3829	transcription factor binding
CD007_11870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CD007_11875	COG2079	MmgE PrpD family protein
CD007_11880	COG0372	Belongs to the citrate synthase family
CD007_11885	COG1960	acyl-CoA dehydrogenase activity
CD007_11890	COG1250	3-hydroxyacyl-CoA dehydrogenase
CD007_11895	COG0183	Belongs to the thiolase family
CD007_11900	COG0584	glycerophosphoryl diester phosphodiesterase
CD007_11905	COG0860	N-Acetylmuramoyl-L-alanine amidase
CD007_11915	COG1902	pentaerythritol trinitrate reductase activity
CD007_11920	COG0745	RESPONSE REGULATOR receiver
CD007_11925	COG0750	zinc metalloprotease
CD007_11930	COG0497	DNA recombination
CD007_11935	COG1438	arginine binding
CD007_11940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CD007_11945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CD007_11950	COG0142	geranyltranstransferase activity
CD007_11955	COG1722	exodeoxyribonuclease VII activity
CD007_11960	COG1570	exodeoxyribonuclease VII activity
CD007_11965	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CD007_11970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CD007_11975	COG1302	Protein conserved in bacteria
CD007_11980	COG0439	Biotin carboxylase
CD007_11985	COG0511	ligase activity, forming carbon-carbon bonds
CD007_12025	COG3854	ATPases associated with a variety of cellular activities
CD007_12035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CD007_12040	COG0006	proline dipeptidase activity
CD007_12045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CD007_12055	COG3872	metal-dependent enzyme
CD007_12065	COG1752	Esterase of the alpha-beta hydrolase superfamily
CD007_12070	COG1321	iron dependent repressor
CD007_12075	COG0095	Lipoate-protein ligase
CD007_12080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CD007_12085	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CD007_12090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CD007_12095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CD007_12100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CD007_12115	COG1396	sequence-specific DNA binding
CD007_12125	COG0681	Belongs to the peptidase S26 family
CD007_12150	COG4940	Competence protein ComGF
CD007_12160	COG4970	Tfp pilus assembly protein FimT
CD007_12165	COG4537	Required for transformation and DNA binding
CD007_12170	COG1459	type II secretion system
CD007_12175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CD007_12185	COG0598	Magnesium transport protein CorA
CD007_12190	COG1253	flavin adenine dinucleotide binding
CD007_12195	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_12205	COG1393	Belongs to the ArsC family
CD007_12215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_12225	COG0011	TIGRFAM Protein of
CD007_12235	COG2866	Carboxypeptidase
CD007_12240	COG1368	sulfuric ester hydrolase activity
CD007_12245	COG1940	carbohydrate kinase activity
CD007_12250	COG4483	Protein conserved in bacteria
CD007_12255	COG0457	Tetratricopeptide repeat
CD007_12255	COG0705	Rhomboid family
CD007_12265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CD007_12270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CD007_12275	COG0438	transferase activity, transferring glycosyl groups
CD007_12290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CD007_12295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CD007_12300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CD007_12305	COG0581	inorganic phosphate transmembrane transporter activity
CD007_12310	COG0573	inorganic phosphate transmembrane transporter activity
CD007_12315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CD007_12325	COG0477	Major facilitator Superfamily
CD007_12330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CD007_12335	COG2839	Protein conserved in bacteria
CD007_12340	COG5521	maltodextrose utilization protein MalA
CD007_12345	COG1388	LysM domain
CD007_12350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CD007_12355	COG4709	membrane
CD007_12360	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CD007_12365	COG0735	belongs to the Fur family
CD007_12370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CD007_12380	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CD007_12385	COG0513	Belongs to the DEAD box helicase family
CD007_12395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CD007_12400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CD007_12405	COG2384	SAM-dependent methyltransferase
CD007_12410	COG2010	Cytochrome c
CD007_12420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CD007_12425	COG0358	DNA primase activity
CD007_12430	COG1671	Belongs to the UPF0178 family
CD007_12435	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CD007_12440	COG0517	IMP dehydrogenase activity
CD007_12445	COG0751	glycine-tRNA ligase activity
CD007_12450	COG0752	glycyl-tRNA synthetase alpha subunit
CD007_12455	COG1381	Involved in DNA repair and RecF pathway recombination
CD007_12465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CD007_12470	COG0295	cytidine deaminase activity
CD007_12475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CD007_12480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CD007_12485	COG1480	7TM receptor with intracellular HD hydrolase
CD007_12490	COG1702	phosphate starvation-inducible protein PhoH
CD007_12495	COG0561	phosphatase activity
CD007_12510	COG4864	UPF0365 protein
CD007_12515	COG1030	water channel activity
CD007_12520	COG1610	YqeY-like protein
CD007_12525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CD007_12530	COG1283	sodium-dependent phosphate transmembrane transporter activity
CD007_12535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CD007_12540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CD007_12545	COG2264	protein methyltransferase activity
CD007_12550	COG0484	heat shock protein binding
CD007_12555	COG0443	Heat shock 70 kDa protein
CD007_12560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CD007_12565	COG1420	regulation of RNA biosynthetic process
CD007_12570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CD007_12575	COG0481	GTPase activity
CD007_12585	COG0860	N-Acetylmuramoyl-L-alanine amidase
CD007_12590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CD007_12595	COG0268	Binds directly to 16S ribosomal RNA
CD007_12600	COG1466	dna polymerase III delta subunit
CD007_12610	COG2333	competence protein COMEC
CD007_12610	COG0658	competence protein
CD007_12615	COG2131	deaminase
CD007_12620	COG1555	photosystem II stabilization
CD007_12620	COG1596	polysaccharide export
CD007_12625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CD007_12630	COG2226	methyltransferase
CD007_12635	COG0799	negative regulation of ribosome biogenesis
CD007_12640	COG1713	HD superfamily hydrolase involved in NAD metabolism
CD007_12645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CD007_12650	COG1534	Rna-binding protein
CD007_12655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CD007_12660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CD007_12665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CD007_12675	COG2755	lipolytic protein G-D-S-L family
CD007_12680	COG3409	Peptidoglycan-binding domain 1 protein
CD007_12680	COG5632	N-Acetylmuramoyl-L-alanine amidase
CD007_12685	COG0398	Pfam SNARE associated Golgi protein
CD007_12690	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CD007_12700	COG3209	COG3209 Rhs family protein
CD007_12710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CD007_12720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CD007_12725	COG0798	PFAM Bile acid sodium symporter
CD007_12730	COG0346	lactoylglutathione lyase activity
CD007_12735	COG0640	Transcriptional regulator
CD007_12740	COG3403	YqcI/YcgG family
CD007_12745	COG0457	Tetratricopeptide repeat
CD007_12760	COG5444	nuclease activity
CD007_12780	COG5632	N-Acetylmuramoyl-L-alanine amidase
CD007_12780	COG3409	Peptidoglycan-binding domain 1 protein
CD007_12785	COG4824	toxin secretion phage lysis holin
CD007_12815	COG3778	Protein conserved in bacteria
CD007_12820	COG3299	homolog of phage Mu protein gp47
CD007_12825	COG3628	GPW Gp25 family protein
CD007_12835	COG4193	domain, Protein
CD007_12840	COG1652	LysM domain
CD007_12845	COG3953	SLT domain
CD007_12845	COG5280	Phage tail tape measure protein TP901
CD007_12910	COG4653	Phage capsid family
CD007_12915	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CD007_12925	COG2369	cell adhesion
CD007_12930	COG5518	Phage portal protein
CD007_12935	COG1783	phage Terminase large subunit
CD007_12940	COG5484	DNA packaging
CD007_12950	COG3677	Transposase
CD007_12965	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CD007_12975	COG1484	DNA-dependent DNA replication
CD007_12980	COG3935	DnaD domain protein
CD007_12985	COG3723	Recombinational DNA repair protein, rece pathway
CD007_12990	COG5377	YqaJ viral recombinase family
CD007_13015	COG1476	TRANSCRIPTIONal
CD007_13020	COG3620	sequence-specific DNA binding
CD007_13030	COG0563	adenylate kinase activity
CD007_13035	COG2856	Zn peptidase
CD007_13045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CD007_13055	COG3223	Belongs to the PsiE family
CD007_13060	COG0642	Histidine kinase
CD007_13060	COG5002	protein histidine kinase activity
CD007_13065	COG0745	RESPONSE REGULATOR receiver
CD007_13070	COG2311	Membrane
CD007_13075	COG0454	-acetyltransferase
CD007_13080	COG2249	NAD(P)H dehydrogenase (quinone) activity
CD007_13090	COG0730	response to heat
CD007_13095	COG0425	Belongs to the sulfur carrier protein TusA family
CD007_13110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CD007_13110	COG0425	Belongs to the sulfur carrier protein TusA family
CD007_13120	COG2210	Belongs to the sulfur carrier protein TusA family
CD007_13125	COG1937	Protein conserved in bacteria
CD007_13140	COG0662	Cupin 2, conserved barrel domain protein
CD007_13155	COG0789	Transcriptional regulator
CD007_13155	COG4978	Transcriptional regulator
CD007_13160	COG2814	Major facilitator Superfamily
CD007_13165	COG0456	acetyltransferase
CD007_13170	COG1253	flavin adenine dinucleotide binding
CD007_13180	COG0697	spore germination
CD007_13185	COG0583	DNA-binding transcription factor activity
CD007_13190	COG2072	flavoprotein involved in K transport
CD007_13195	COG1230	cation diffusion facilitator family transporter
CD007_13200	COG1942	4-Oxalocrotonate Tautomerase
CD007_13205	COG0583	DNA-binding transcription factor activity
CD007_13215	COG1114	Component of the transport system for branched-chain amino acids
CD007_13220	COG1687	branched-chain amino acid
CD007_13225	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CD007_13230	COG1522	sequence-specific DNA binding
CD007_13235	COG2732	(Barnase) inhibitor
CD007_13240	COG2124	cytochrome p450
CD007_13250	COG1335	isochorismatase
CD007_13260	COG2318	DinB family
CD007_13270	COG2070	2-Nitropropane dioxygenase
CD007_13285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CD007_13295	COG2186	Transcriptional regulator
CD007_13305	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_13310	COG3958	Transketolase
CD007_13315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CD007_13320	COG0477	Major facilitator Superfamily
CD007_13325	COG1846	Transcriptional regulator
CD007_13330	COG3443	Belongs to the bacterial solute-binding protein 9 family
CD007_13335	COG1595	DNA-templated transcription, initiation
CD007_13340	COG0667	Aldo Keto reductase
CD007_13345	COG2851	Citrate transporter
CD007_13350	COG0583	DNA-binding transcription factor activity
CD007_13355	COG2828	Protein conserved in bacteria
CD007_13360	COG3409	Peptidoglycan-binding domain 1 protein
CD007_13365	COG5566	PFAM Mor transcription activator
CD007_13370	COG0596	Alpha beta hydrolase
CD007_13375	COG4991	sh3 domain protein
CD007_13380	COG4991	sh3 domain protein
CD007_13385	COG0346	lactoylglutathione lyase activity
CD007_13395	COG5577	PFAM Coat F domain
CD007_13400	COG1063	alcohol dehydrogenase
CD007_13410	COG5577	PFAM Coat F domain
CD007_13415	COG0789	Transcriptional regulator
CD007_13425	COG1064	alcohol dehydrogenase
CD007_13430	COG0693	protein deglycase activity
CD007_13435	COG1621	beta-fructofuranosidase activity
CD007_13440	COG3716	PTS system mannose fructose sorbose family IID component
CD007_13445	COG3715	PTS system
CD007_13450	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_13455	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_13460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CD007_13460	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CD007_13465	COG1113	amino acid transport
CD007_13470	COG1280	lysine exporter protein (LysE YggA)
CD007_13475	COG1378	Sugar-specific transcriptional regulator TrmB
CD007_13480	COG1595	DNA-templated transcription, initiation
CD007_13490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CD007_13490	COG2755	lipolytic protein G-D-S-L family
CD007_13500	COG2124	cytochrome p450
CD007_13500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CD007_13505	COG1309	transcriptional regulator
CD007_13510	COG2226	methyltransferase
CD007_13520	COG2116	formate transmembrane transporter activity
CD007_13525	COG5609	conserved protein (DUF2294)
CD007_13530	COG3383	formate dehydrogenase (NAD+) activity
CD007_13535	COG2427	Protein of unknown function (DUF1641)
CD007_13545	COG0626	cystathionine gamma-synthase activity
CD007_13550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CD007_13555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CD007_13560	COG2226	methyltransferase
CD007_13575	COG0768	penicillin binding
CD007_13580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CD007_13585	COG0572	uridine kinase
CD007_13605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CD007_13610	COG3906	Belongs to the UPF0473 family
CD007_13615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CD007_13620	COG4472	Bacterial protein of unknown function (DUF965)
CD007_13625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CD007_13630	COG0628	permease
CD007_13635	COG1126	abc transporter atp-binding protein
CD007_13640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CD007_13645	COG0765	amino acid transport
CD007_13650	COG0765	amino acid transport
CD007_13665	COG3881	PFAM PRC-barrel domain
CD007_13670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CD007_13675	COG0457	Tetratricopeptide repeat
CD007_13680	COG0482	sulfurtransferase activity
CD007_13685	COG1104	cysteine desulfurase activity
CD007_13690	COG1959	2 iron, 2 sulfur cluster binding
CD007_13695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CD007_13700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CD007_13710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CD007_13715	COG0124	histidyl-tRNA synthetase
CD007_13725	COG3103	Sh3 type 3 domain protein
CD007_13725	COG4991	sh3 domain protein
CD007_13725	COG0860	N-Acetylmuramoyl-L-alanine amidase
CD007_13730	COG1490	D-aminoacyl-tRNA deacylase activity
CD007_13735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CD007_13740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CD007_13745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CD007_13745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CD007_13750	COG5416	Lipopolysaccharide assembly protein A domain
CD007_13755	COG0490	domain, Protein
CD007_13760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CD007_13760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CD007_13770	COG2244	polysaccharide biosynthetic process
CD007_13775	COG2323	membrane
CD007_13785	COG1862	Preprotein translocase
CD007_13790	COG0343	queuine tRNA-ribosyltransferase activity
CD007_13795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CD007_13805	COG2255	four-way junction helicase activity
CD007_13810	COG0632	four-way junction helicase activity
CD007_13820	COG2814	Major facilitator Superfamily
CD007_13825	COG0673	inositol 2-dehydrogenase activity
CD007_13830	COG2112	serine threonine protein kinase
CD007_13845	COG1115	amino acid carrier protein
CD007_13850	COG0217	transcriptional regulatory protein
CD007_13860	COG1388	LysM domain
CD007_13865	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CD007_13870	COG0157	Belongs to the NadC ModD family
CD007_13875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CD007_13880	COG1104	cysteine desulfurase activity
CD007_13885	COG1827	regulation of RNA biosynthetic process
CD007_13890	COG0077	Prephenate dehydratase
CD007_13895	COG4492	Belongs to the UPF0735 family
CD007_13900	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CD007_13905	COG3290	protein histidine kinase activity
CD007_13910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CD007_13915	COG2868	ribosomal protein
CD007_13920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CD007_13925	COG1994	Peptidase M50
CD007_13930	COG0739	heme binding
CD007_13935	COG2894	cell division
CD007_13940	COG0850	regulation of cytokinetic process
CD007_13945	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CD007_13950	COG1792	Involved in formation and maintenance of cell shape
CD007_13955	COG1077	Cell shape determining protein MreB Mrl
CD007_13960	COG2003	Belongs to the UPF0758 family
CD007_13965	COG0424	maF-like protein
CD007_13975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CD007_13980	COG0285	dihydrofolate synthase activity
CD007_13985	COG0525	valine-tRNA ligase activity
CD007_13995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CD007_14000	COG1388	LysM domain
CD007_14005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CD007_14010	COG0113	porphobilinogen synthase activity
CD007_14015	COG1587	Uroporphyrinogen-III synthase
CD007_14020	COG0181	hydroxymethylbilane synthase activity
CD007_14025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CD007_14030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CD007_14040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CD007_14045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CD007_14050	COG0470	DNA polymerase III
CD007_14050	COG1067	ATP-dependent peptidase activity
CD007_14055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CD007_14060	COG0544	peptidyl-prolyl cis-trans isomerase activity
CD007_14065	COG1477	protein flavinylation
CD007_14065	COG0457	Tetratricopeptide repeat
CD007_14070	COG0066	3-isopropylmalate dehydratase activity
CD007_14075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CD007_14080	COG0473	3-isopropylmalate dehydrogenase activity
CD007_14085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CD007_14090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CD007_14095	COG0440	acetolactate synthase activity
CD007_14100	COG0028	Belongs to the TPP enzyme family
CD007_14115	COG0454	-acetyltransferase
CD007_14120	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CD007_14130	COG0622	Phosphoesterase
CD007_14135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CD007_14140	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CD007_14145	COG5401	PFAM Sporulation and spore germination
CD007_14150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CD007_14155	COG1846	Transcriptional regulator
CD007_14160	COG2197	response regulator
CD007_14165	COG0824	Thioesterase
CD007_14170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CD007_14175	COG1053	succinate dehydrogenase
CD007_14180	COG2009	succinate dehydrogenase
CD007_14185	COG1719	4-vinyl reductase, 4VR
CD007_14190	COG0527	aspartate kinase activity
CD007_14200	COG0322	excinuclease ABC activity
CD007_14205	COG3118	belongs to the thioredoxin family
CD007_14215	COG3534	alpha-L-arabinofuranosidase
CD007_14220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CD007_14225	COG2086	electron transfer activity
CD007_14230	COG1024	Enoyl-CoA hydratase
CD007_14235	COG1309	transcriptional regulator
CD007_14240	COG0318	PFAM AMP-dependent synthetase and ligase
CD007_14250	COG3766	membrane
CD007_14255	COG1193	negative regulation of DNA recombination
CD007_14260	COG1796	DNA polymerase
CD007_14260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CD007_14265	COG1286	toxin biosynthetic process
CD007_14270	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CD007_14275	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CD007_14280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CD007_14280	COG0072	phenylalanine-tRNA ligase activity
CD007_14285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CD007_14295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CD007_14305	COG3835	regulator
CD007_14310	COG0277	FAD linked oxidase domain protein
CD007_14315	COG0247	lactate metabolic process
CD007_14320	COG0346	lactoylglutathione lyase activity
CD007_14330	COG1966	Carbon starvation protein
CD007_14335	COG3534	alpha-L-arabinofuranosidase
CD007_14340	COG0395	ABC-type sugar transport system, permease component
CD007_14345	COG1175	transmembrane transport
CD007_14350	COG1653	transport
CD007_14355	COG0371	Dehydrogenase
CD007_14360	COG0647	UMP catabolic process
CD007_14365	COG0235	Class ii aldolase
CD007_14370	COG1069	ribulokinase activity
CD007_14375	COG2160	L-arabinose isomerase activity
CD007_14380	COG3507	Belongs to the glycosyl hydrolase 43 family
CD007_14385	COG1363	Peptidase, m42
CD007_14395	COG3326	Membrane
CD007_14400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CD007_14405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CD007_14410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CD007_14420	COG1346	cytolysis
CD007_14425	COG1380	Effector of murein hydrolase LrgA
CD007_14430	COG3279	Response regulator of the LytR AlgR family
CD007_14435	COG3275	phosphorelay sensor kinase activity
CD007_14445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CD007_14455	COG0398	Pfam SNARE associated Golgi protein
CD007_14460	COG1484	DNA-dependent DNA replication
CD007_14465	COG3611	Membrane attachment protein
CD007_14470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CD007_14475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CD007_14480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CD007_14485	COG1733	regulation of RNA biosynthetic process
CD007_14490	COG2814	Major facilitator Superfamily
CD007_14495	COG0656	L-ascorbic acid biosynthetic process
CD007_14500	COG0237	dephospho-CoA kinase activity
CD007_14505	COG1971	Probably functions as a manganese efflux pump
CD007_14510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CD007_14515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CD007_14515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CD007_14520	COG5002	protein histidine kinase activity
CD007_14525	COG0745	RESPONSE REGULATOR receiver
CD007_14535	COG0039	L-malate dehydrogenase activity
CD007_14540	COG0538	isocitrate dehydrogenase activity
CD007_14545	COG0372	Belongs to the citrate synthase family
CD007_14550	COG2707	UPF0756 membrane protein
CD007_14555	COG0628	permease
CD007_14560	COG3030	protein affecting phage T7 exclusion by the F plasmid
CD007_14565	COG0469	pyruvate kinase activity
CD007_14570	COG0205	6-phosphofructokinase activity
CD007_14575	COG0825	malonyl-CoA metabolic process
CD007_14580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CD007_14585	COG0281	malic enzyme
CD007_14590	COG0587	DNA-directed DNA polymerase activity
CD007_14610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CD007_14620	COG4109	DRTGG domain
CD007_14625	COG0730	response to heat
CD007_14630	COG1473	amidohydrolase
CD007_14635	COG0196	riboflavin kinase activity
CD007_14640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CD007_14645	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CD007_14650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CD007_14655	COG1126	abc transporter atp-binding protein
CD007_14660	COG0765	amino acid transport
CD007_14665	COG0765	amino acid transport
CD007_14670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CD007_14675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CD007_14680	COG0454	-acetyltransferase
CD007_14685	COG0583	DNA-binding transcription factor activity
CD007_14690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CD007_14695	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_14705	COG0165	Argininosuccinate lyase
CD007_14710	COG0137	argininosuccinate synthase activity
CD007_14715	COG0521	Mo-molybdopterin cofactor biosynthetic process
CD007_14720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CD007_14730	COG0827	DNA restriction-modification system
CD007_14735	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CD007_14740	COG3874	Sporulation protein YtfJ
CD007_14750	COG1714	RDD family
CD007_14755	COG0616	signal peptide processing
CD007_14760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CD007_14765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CD007_14770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CD007_14780	COG0301	tRNA thio-modification
CD007_14785	COG1104	cysteine desulfurase activity
CD007_14790	COG1114	Component of the transport system for branched-chain amino acids
CD007_14795	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CD007_14800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CD007_14805	COG1309	transcriptional regulator
CD007_14810	COG1956	GAF domain-containing protein
CD007_14815	COG2199	diguanylate cyclase activity
CD007_14815	COG2203	Gaf domain
CD007_14825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CD007_14830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CD007_14840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CD007_14845	COG0454	-acetyltransferase
CD007_14850	COG0517	IMP dehydrogenase activity
CD007_14855	COG0123	including yeast histone deacetylase and acetoin utilization protein
CD007_14860	COG1360	Flagellar Motor Protein
CD007_14865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CD007_14870	COG1609	Transcriptional regulator
CD007_14875	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CD007_14875	COG1605	Chorismate mutase
CD007_14880	COG3118	belongs to the thioredoxin family
CD007_14885	COG4980	gas vesicle protein
CD007_14890	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CD007_14895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CD007_14900	COG1674	ftsk spoiiie
CD007_14905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CD007_14910	COG4848	Belongs to the UPF0354 family
CD007_14915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_14925	COG1363	Peptidase, m42
CD007_14930	COG5584	Small secreted protein
CD007_14935	COG0281	malic enzyme
CD007_14940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_14945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CD007_14955	COG0510	thiamine kinase activity
CD007_14960	COG1523	belongs to the glycosyl hydrolase 13 family
CD007_14965	COG1597	lipid kinase activity
CD007_14975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CD007_14980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CD007_14985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CD007_14990	COG2252	PERMEase
CD007_14995	COG4473	ABC transporter
CD007_15000	COG1131	(ABC) transporter
CD007_15005	COG1349	DNA-binding transcription factor activity
CD007_15010	COG1187	pseudouridine synthase activity
CD007_15015	COG2244	polysaccharide biosynthetic process
CD007_15020	COG2081	HI0933 family
CD007_15025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CD007_15035	COG5578	integral membrane protein
CD007_15040	COG0673	inositol 2-dehydrogenase activity
CD007_15045	COG1653	transport
CD007_15050	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CD007_15055	COG4209	transmembrane transport
CD007_15060	COG2207	Transcriptional regulator
CD007_15065	COG1653	transport
CD007_15070	COG0395	ABC-type sugar transport system, permease component
CD007_15075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CD007_15080	COG2124	cytochrome p450
CD007_15085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CD007_15095	COG0156	8-amino-7-oxononanoate synthase activity
CD007_15100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CD007_15110	COG1073	alpha beta
CD007_15135	COG1486	melibiose metabolic process
CD007_15140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CD007_15145	COG0495	leucyl-tRNA aminoacylation
CD007_15155	COG1366	Belongs to the anti-sigma-factor antagonist family
CD007_15155	COG2202	Pas domain
CD007_15160	COG2814	Major facilitator Superfamily
CD007_15165	COG2433	Pfam Transposase IS66
CD007_15170	COG0577	efflux transmembrane transporter activity
CD007_15175	COG1136	(ABC) transporter
CD007_15180	COG2205	protein histidine kinase activity
CD007_15185	COG0745	RESPONSE REGULATOR receiver
CD007_15190	COG0577	efflux transmembrane transporter activity
CD007_15195	COG1136	(ABC) transporter
CD007_15210	COG1131	(ABC) transporter
CD007_15215	COG1725	Transcriptional regulator
CD007_15225	COG1242	4 iron, 4 sulfur cluster binding
CD007_15230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CD007_15240	COG2267	carboxylic ester hydrolase activity
CD007_15245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CD007_15250	COG1113	amino acid transport
CD007_15255	COG0367	asparagine synthase
CD007_15260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CD007_15265	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CD007_15275	COG1506	peptidase
CD007_15280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CD007_15285	COG1116	anion transmembrane transporter activity
CD007_15290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CD007_15295	COG0494	nUDIX hydrolase
CD007_15300	COG4824	toxin secretion phage lysis holin
CD007_15305	COG0783	Belongs to the Dps family
CD007_15320	COG1854	S-ribosylhomocysteine lyase activity
CD007_15325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CD007_15330	COG0288	reversible hydration of carbon dioxide
CD007_15335	COG0254	rRNA binding
CD007_15340	COG1271	oxidase subunit
CD007_15345	COG1294	oxidase, subunit
CD007_15355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CD007_15360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CD007_15360	COG1321	iron dependent repressor
CD007_15365	COG1121	(ABC) transporter
CD007_15370	COG0803	Belongs to the bacterial solute-binding protein 9 family
CD007_15375	COG4948	Mandelate Racemase Muconate Lactonizing
CD007_15380	COG0318	PFAM AMP-dependent synthetase and ligase
CD007_15385	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CD007_15390	COG0596	Alpha beta hydrolase
CD007_15395	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CD007_15400	COG1169	isochorismate synthase
CD007_15405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CD007_15410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CD007_15415	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CD007_15420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CD007_15425	COG0438	transferase activity, transferring glycosyl groups
CD007_15435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CD007_15440	COG0438	transferase activity, transferring glycosyl groups
CD007_15445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CD007_15450	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CD007_15455	COG0058	SHG alpha-glucan phosphorylase activity
CD007_15460	COG0297	glycogen (starch) synthase activity
CD007_15465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CD007_15470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CD007_15475	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CD007_15600	COG3859	Proton-coupled thiamine transporter YuaJ
CD007_15605	COG1247	-acetyltransferase
CD007_15610	COG2268	Band 7 protein
CD007_15615	COG1585	Membrane protein implicated in regulation of membrane protease activity
CD007_15620	COG2318	DinB family
CD007_15630	COG1454	alcohol dehydrogenase
CD007_15640	COG1510	regulation of RNA biosynthetic process
CD007_15650	COG0569	domain protein
CD007_15655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CD007_15660	COG4682	membrane
CD007_15665	COG1705	Flagellar rod assembly protein muramidase FlgJ
CD007_15670	COG0477	Major facilitator Superfamily
CD007_15675	COG5553	Cysteine dioxygenase type I
CD007_15685	COG1968	undecaprenyl-diphosphatase activity
CD007_15690	COG0628	permease
CD007_15695	COG0673	inositol 2-dehydrogenase activity
CD007_15700	COG4806	L-rhamnose isomerase
CD007_15705	COG3254	rhamnose metabolic process
CD007_15710	COG1070	Carbohydrate kinase
CD007_15715	COG1349	DNA-binding transcription factor activity
CD007_15720	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_15720	COG3347	Dehydrogenase
CD007_15730	COG0840	transmembrane signaling receptor activity
CD007_15735	COG0840	transmembrane signaling receptor activity
CD007_15740	COG0840	transmembrane signaling receptor activity
CD007_15745	COG0840	transmembrane signaling receptor activity
CD007_15760	COG0432	Pfam Uncharacterised protein family UPF0047
CD007_15765	COG0366	Alpha amylase catalytic
CD007_15770	COG1253	flavin adenine dinucleotide binding
CD007_15775	COG2738	Putative neutral zinc metallopeptidase
CD007_15790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CD007_15805	COG0166	Belongs to the GPI family
CD007_15810	COG1979	alcohol dehydrogenase
CD007_15815	COG1979	alcohol dehydrogenase
CD007_15820	COG2155	Conserved Protein
CD007_15825	COG1098	S1 RNA binding domain
CD007_15830	COG0436	Aminotransferase
CD007_15835	COG1522	sequence-specific DNA binding
CD007_15840	COG2267	carboxylic ester hydrolase activity
CD007_15850	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CD007_15855	COG2205	protein histidine kinase activity
CD007_15865	COG5018	Exonuclease
CD007_15875	COG2814	Major facilitator Superfamily
CD007_15880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CD007_15885	COG3011	Protein conserved in bacteria
CD007_15895	COG3290	protein histidine kinase activity
CD007_15900	COG4565	transcriptional regulatory protein
CD007_15925	COG3493	citrate carrier protein
CD007_15935	COG2111	Na H antiporter
CD007_15935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CD007_15940	COG2111	Na H antiporter
CD007_15945	COG1006	Multisubunit Na H antiporter MnhC subunit
CD007_15950	COG0651	ATP synthesis coupled electron transport
CD007_15955	COG1863	multisubunit Na H antiporter MnhE subunit
CD007_15960	COG2212	antiporter activity
CD007_15965	COG1320	monovalent cation:proton antiporter activity
CD007_15970	COG2050	protein possibly involved in aromatic compounds catabolism
CD007_15975	COG2197	response regulator
CD007_15980	COG4585	Histidine kinase
CD007_15990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CD007_15995	COG1335	isochorismatase
CD007_16000	COG5506	Protein of unknown function (DUF1694)
CD007_16015	COG0628	permease
CD007_16030	COG1418	mRNA catabolic process
CD007_16035	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_16045	COG1511	domain protein
CD007_16050	COG1674	ftsk spoiiie
CD007_16050	COG0433	COG0433 Predicted ATPase
CD007_16055	COG4499	WXG100 protein secretion system (Wss), protein YukC
CD007_16060	COG5417	Belongs to the EsaB family
CD007_16065	COG4842	Belongs to the WXG100 family
CD007_16070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CD007_16070	COG2508	Transcriptional regulator
CD007_16075	COG0686	Belongs to the AlaDH PNT family
CD007_16080	COG5634	Uncharacterized conserved protein (DUF2278)
CD007_16085	COG3251	PFAM MbtH domain protein
CD007_16090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_16095	COG1535	isochorismatase
CD007_16095	COG3433	isochorismatase activity
CD007_16100	COG1021	2,3-dihydroxybenzoate-AMP ligase
CD007_16105	COG1169	isochorismate synthase
CD007_16110	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_16115	COG2819	hydrolase of the alpha beta superfamily
CD007_16120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CD007_16125	COG1268	BioY protein
CD007_16130	COG2056	Na+-H+ antiporter family
CD007_16135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CD007_16140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CD007_16145	COG3584	3D domain protein
CD007_16160	COG1252	NADH dehydrogenase
CD007_16165	COG0492	ferredoxin-NADP+ reductase activity
CD007_16175	COG0516	GMP reductase activity
CD007_16180	COG2808	Putative FMN-binding domain
CD007_16185	COG0456	acetyltransferase
CD007_16190	COG0316	Belongs to the HesB IscA family
CD007_16195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CD007_16200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CD007_16205	COG4844	belongs to the
CD007_16210	COG1252	NADH dehydrogenase
CD007_16215	COG4837	Protein of unknown function (DUF1462)
CD007_16220	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CD007_16225	COG1506	peptidase
CD007_16225	COG4946	Tricorn protease homolog
CD007_16225	COG0823	Involved in the tonB-independent uptake of proteins
CD007_16230	COG0083	homoserine kinase activity
CD007_16235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CD007_16240	COG0460	homoserine dehydrogenase
CD007_16245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CD007_16250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CD007_16255	COG0647	UMP catabolic process
CD007_16260	COG2445	Protein of unknown function DUF86
CD007_16265	COG4470	Protein conserved in bacteria
CD007_16275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CD007_16280	COG0739	heme binding
CD007_16290	COG3377	Domain of unknown function (DUF1805)
CD007_16295	COG0737	Belongs to the 5'-nucleotidase family
CD007_16300	COG0730	response to heat
CD007_16305	COG1801	Protein of unknown function DUF72
CD007_16315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CD007_16320	COG2508	Transcriptional regulator
CD007_16325	COG2233	PERMEase
CD007_16330	COG2233	PERMEase
CD007_16335	COG3195	allantoin biosynthetic process
CD007_16335	COG3648	Uricase
CD007_16340	COG2351	hydroxyisourate hydrolase activity
CD007_16350	COG2080	2 iron, 2 sulfur cluster binding
CD007_16355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CD007_16360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CD007_16365	COG2068	MobA-Related Protein
CD007_16370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CD007_16375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CD007_16380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CD007_16385	COG2356	endonuclease I
CD007_16390	COG3842	ATPase activity
CD007_16395	COG2188	Transcriptional regulator
CD007_16400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CD007_16405	COG0395	ABC-type sugar transport system, permease component
CD007_16410	COG1175	transmembrane transport
CD007_16415	COG1653	transport
CD007_16420	COG2222	sugar isomerase
CD007_16425	COG0322	excinuclease ABC activity
CD007_16430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CD007_16445	COG0346	lactoylglutathione lyase activity
CD007_16450	COG0640	Transcriptional regulator
CD007_16455	COG0719	Fe-S assembly protein
CD007_16460	COG0822	iron-sulfur transferase activity
CD007_16465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CD007_16470	COG0719	Fe-S assembly protein
CD007_16475	COG0396	ATPase activity
CD007_16490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CD007_16495	COG1464	Belongs to the NlpA lipoprotein family
CD007_16500	COG2011	ABC-type metal ion transport system permease component
CD007_16505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CD007_16515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CD007_16520	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CD007_16530	COG0509	glycine decarboxylation via glycine cleavage system
CD007_16535	COG1393	Belongs to the ArsC family
CD007_16540	COG1960	acyl-CoA dehydrogenase activity
CD007_16545	COG0183	Belongs to the thiolase family
CD007_16550	COG1024	Enoyl-CoA hydratase
CD007_16550	COG1250	3-hydroxyacyl-CoA dehydrogenase
CD007_16560	COG0506	proline dehydrogenase activity
CD007_16570	COG5577	PFAM Coat F domain
CD007_16575	COG1846	Transcriptional regulator
CD007_16580	COG0477	Major facilitator Superfamily
CD007_16585	COG1942	4-Oxalocrotonate Tautomerase
CD007_16595	COG0583	DNA-binding transcription factor activity
CD007_16605	COG1120	ATPase activity
CD007_16620	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_16625	COG0783	Belongs to the Dps family
CD007_16630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CD007_16635	COG0745	RESPONSE REGULATOR receiver
CD007_16640	COG2770	Histidine kinase
CD007_16640	COG2205	protein histidine kinase activity
CD007_16650	COG1309	transcriptional regulator
CD007_16655	COG0114	fumarate hydratase activity
CD007_16665	COG0697	spore germination
CD007_16670	COG0814	amino acid
CD007_16680	COG2197	response regulator
CD007_16685	COG4585	Histidine kinase
CD007_16690	COG4758	membrane
CD007_16695	COG3595	metallopeptidase activity
CD007_16700	COG1842	Phage shock protein A
CD007_16705	COG4758	membrane
CD007_16710	COG2814	Major facilitator Superfamily
CD007_16715	COG2096	Adenosyltransferase
CD007_16720	COG1120	ATPase activity
CD007_16725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_16730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CD007_16735	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_16740	COG3386	PFAM SMP-30 Gluconolaconase
CD007_16745	COG2205	protein histidine kinase activity
CD007_16750	COG0745	RESPONSE REGULATOR receiver
CD007_16760	COG1191	sigma factor activity
CD007_16770	COG2140	Oxalate decarboxylase
CD007_16780	COG0577	efflux transmembrane transporter activity
CD007_16785	COG1136	(ABC) transporter
CD007_16790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CD007_16795	COG1120	ATPase activity
CD007_16800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_16805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CD007_16810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CD007_16820	COG0531	amino acid
CD007_16835	COG1988	membrane-bound metal-dependent
CD007_16840	COG1368	sulfuric ester hydrolase activity
CD007_16845	COG1910	domain protein
CD007_16850	COG0725	ABC transporter, periplasmic molybdate-binding protein
CD007_16855	COG4149	molybdate abc transporter
CD007_16860	COG0656	L-ascorbic acid biosynthetic process
CD007_16870	COG0025	NhaP-type Na H and K H
CD007_16875	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CD007_16880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CD007_16885	COG3973	AAA domain
CD007_16895	COG2860	membrane
CD007_16900	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CD007_16905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CD007_16910	COG2217	Heavy metal translocating P-type atpase
CD007_16915	COG2217	Heavy metal translocating P-type atpase
CD007_16920	COG2608	mercury ion transmembrane transporter activity
CD007_16925	COG1937	Protein conserved in bacteria
CD007_16930	COG0673	inositol 2-dehydrogenase activity
CD007_16935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CD007_16940	COG1289	transmembrane transporter activity
CD007_16950	COG2076	Multidrug Resistance protein
CD007_16955	COG1309	transcriptional regulator
CD007_16960	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_16985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CD007_16990	COG0557	exoribonuclease II activity
CD007_16995	COG1647	Serine aminopeptidase, S33
CD007_17000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CD007_17005	COG0596	Alpha beta hydrolase
CD007_17010	COG1476	TRANSCRIPTIONal
CD007_17015	COG1396	sequence-specific DNA binding
CD007_17020	COG1396	sequence-specific DNA binding
CD007_17025	COG1733	regulation of RNA biosynthetic process
CD007_17030	COG0840	transmembrane signaling receptor activity
CD007_17085	COG1174	glycine betaine transport
CD007_17090	COG1732	Glycine betaine
CD007_17095	COG1174	glycine betaine transport
CD007_17100	COG1125	glycine betaine transport
CD007_17100	COG0517	IMP dehydrogenase activity
CD007_17105	COG1510	regulation of RNA biosynthetic process
CD007_17110	COG1174	glycine betaine transport
CD007_17115	COG1732	Glycine betaine
CD007_17120	COG1174	glycine betaine transport
CD007_17125	COG0517	IMP dehydrogenase activity
CD007_17125	COG1125	glycine betaine transport
CD007_17130	COG1510	regulation of RNA biosynthetic process
CD007_17135	COG2095	MarC family integral membrane protein
CD007_17145	COG3064	Membrane
CD007_17150	COG4640	response to antibiotic
CD007_17155	COG0456	acetyltransferase
CD007_17160	COG0148	phosphopyruvate hydratase activity
CD007_17165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CD007_17170	COG0149	triose-phosphate isomerase activity
CD007_17175	COG0126	phosphoglycerate kinase activity
CD007_17180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CD007_17185	COG2390	Transcriptional regulator
CD007_17190	COG2814	Major facilitator Superfamily
CD007_17195	COG1609	Transcriptional regulator
CD007_17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CD007_17210	COG0583	DNA-binding transcription factor activity
CD007_17215	COG0697	spore germination
CD007_17220	COG1113	amino acid transport
CD007_17225	COG3858	chitin binding
CD007_17230	COG1556	Lactate utilization protein
CD007_17235	COG1139	Iron-sulfur cluster binding protein
CD007_17240	COG0247	lactate metabolic process
CD007_17245	COG2197	response regulator
CD007_17250	COG4585	Histidine kinase
CD007_17255	COG0842	Transport permease protein
CD007_17260	COG1131	(ABC) transporter
CD007_17265	COG0596	Alpha beta hydrolase
CD007_17270	COG2208	phosphoserine phosphatase activity
CD007_17275	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CD007_17280	COG1874	Beta-galactosidase
CD007_17285	COG3833	ABC-type maltose transport systems, permease component
CD007_17290	COG1175	transmembrane transport
CD007_17295	COG2182	Extracellular solute-binding protein
CD007_17300	COG1609	Transcriptional regulator
CD007_17305	COG2186	Transcriptional regulator
CD007_17310	COG1620	l-lactate permease
CD007_17315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CD007_17320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CD007_17330	COG5039	Polysaccharide pyruvyl transferase
CD007_17335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CD007_17340	COG0110	maltose O-acetyltransferase activity
CD007_17345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CD007_17350	COG2244	polysaccharide biosynthetic process
CD007_17355	COG1216	Glycosyl transferase, family 2
CD007_17360	COG5039	Polysaccharide pyruvyl transferase
CD007_17365	COG1216	Glycosyl transferase, family 2
CD007_17375	COG0438	transferase activity, transferring glycosyl groups
CD007_17380	COG1215	transferase activity, transferring glycosyl groups
CD007_17385	COG0438	transferase activity, transferring glycosyl groups
CD007_17390	COG1086	Polysaccharide biosynthesis protein
CD007_17395	COG0489	protein tyrosine kinase activity
CD007_17400	COG3944	biosynthesis protein
CD007_17405	COG1396	sequence-specific DNA binding
CD007_17410	COG2272	Belongs to the type-B carboxylesterase lipase family
CD007_17420	COG3479	Phenolic acid decarboxylase
CD007_17430	COG1794	racemase activity, acting on amino acids and derivatives
CD007_17435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CD007_17440	COG1621	beta-fructofuranosidase activity
CD007_17445	COG1621	beta-fructofuranosidase activity
CD007_17450	COG0531	amino acid
CD007_17455	COG1309	transcriptional regulator
CD007_17460	COG2076	Multidrug Resistance protein
CD007_17465	COG2076	Multidrug Resistance protein
CD007_17480	COG0740	serine-type endopeptidase activity
CD007_17485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CD007_17490	COG0366	Alpha amylase catalytic
CD007_17495	COG1554	hydrolase, family 65, central catalytic
CD007_17500	COG5521	maltodextrose utilization protein MalA
CD007_17505	COG3833	ABC-type maltose transport systems, permease component
CD007_17510	COG1175	transmembrane transport
CD007_17515	COG2182	Extracellular solute-binding protein
CD007_17520	COG0366	Alpha amylase catalytic
CD007_17525	COG1609	Transcriptional regulator
CD007_17530	COG1611	Belongs to the LOG family
CD007_17535	COG1694	Mazg nucleotide pyrophosphohydrolase
CD007_17540	COG0659	secondary active sulfate transmembrane transporter activity
CD007_17545	COG0288	reversible hydration of carbon dioxide
CD007_17550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CD007_17555	COG0577	efflux transmembrane transporter activity
CD007_17560	COG1136	(ABC) transporter
CD007_17565	COG5002	protein histidine kinase activity
CD007_17570	COG0745	RESPONSE REGULATOR receiver
CD007_17585	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CD007_17590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_17595	COG1481	regulation of sporulation
CD007_17600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CD007_17605	COG1660	Displays ATPase and GTPase activities
CD007_17610	COG1051	belongs to the nudix hydrolase family
CD007_17615	COG0492	ferredoxin-NADP+ reductase activity
CD007_17620	COG3883	PFAM NLP P60 protein
CD007_17620	COG0791	NLP P60 protein
CD007_17625	COG0457	Tetratricopeptide repeat
CD007_17630	COG1132	(ABC) transporter
CD007_17650	COG0140	phosphoribosyl-ATP diphosphatase activity
CD007_17650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CD007_17655	COG0107	imidazoleglycerol-phosphate synthase activity
CD007_17660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CD007_17665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CD007_17670	COG0131	Imidazoleglycerol-phosphate dehydratase
CD007_17675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CD007_17680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CD007_17685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CD007_17690	COG4990	cell redox homeostasis
CD007_17695	COG5297	Belongs to the glycosyl hydrolase family 6
CD007_17700	COG0110	maltose O-acetyltransferase activity
CD007_17705	COG0546	phosphoglycolate phosphatase activity
CD007_17710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CD007_17715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CD007_17720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CD007_17725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CD007_17730	COG0363	glucosamine-6-phosphate deaminase activity
CD007_17740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CD007_17745	COG1846	Transcriptional regulator
CD007_17760	COG1846	Transcriptional regulator
CD007_17765	COG2814	Major facilitator Superfamily
CD007_17770	COG1950	PFAM Membrane protein of
CD007_17775	COG1983	PspC domain protein
CD007_17780	COG3595	metallopeptidase activity
CD007_17800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CD007_17805	COG0556	nucleotide-excision repair
CD007_17810	COG4897	Protein conserved in bacteria
CD007_17815	COG3848	Pyruvate phosphate dikinase
CD007_17815	COG0574	Belongs to the PEP-utilizing enzyme family
CD007_17820	COG1309	transcriptional regulator
CD007_17825	COG2814	Major facilitator Superfamily
CD007_17830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CD007_17840	COG3409	Peptidoglycan-binding domain 1 protein
CD007_17840	COG0793	Belongs to the peptidase S41A family
CD007_17845	COG2177	Part of the ABC transporter FtsEX involved in
CD007_17850	COG2884	Cell division ATP-binding protein ftsE
CD007_17855	COG2010	Cytochrome c
CD007_17860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CD007_17870	COG0653	protein targeting
CD007_17875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CD007_17890	COG1516	flagellar protein fliS
CD007_17895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CD007_17900	COG1334	flagellar protein FlaG
CD007_17905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CD007_17910	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CD007_17915	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CD007_17925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CD007_17930	COG1256	bacterial-type flagellum assembly
CD007_17930	COG4786	Flagellar basal body rod
CD007_17935	COG3418	PFAM FlgN family protein
CD007_17940	COG2747	anti-sigma28 factor FlgM
CD007_17950	COG1040	competence protein
CD007_17960	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CD007_17965	COG1307	EDD domain protein, DegV family
CD007_17970	COG2197	response regulator
CD007_17975	COG4585	Histidine kinase
CD007_17980	COG1739	Uncharacterized protein family UPF0029
CD007_17985	COG1316	TRANSCRIPTIONal
CD007_17990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CD007_17995	COG0438	transferase activity, transferring glycosyl groups
CD007_18000	COG1215	transferase activity, transferring glycosyl groups
CD007_18005	COG3206	protein involved in exopolysaccharide biosynthesis
CD007_18010	COG3307	-O-antigen
CD007_18015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CD007_18020	COG0297	glycogen (starch) synthase activity
CD007_18020	COG0438	transferase activity, transferring glycosyl groups
CD007_18025	COG2244	polysaccharide biosynthetic process
CD007_18040	COG0860	N-Acetylmuramoyl-L-alanine amidase
CD007_18040	COG2247	cell wall binding repeat
CD007_18045	COG2247	cell wall binding repeat
CD007_18045	COG2385	sporulation resulting in formation of a cellular spore
CD007_18055	COG1316	TRANSCRIPTIONal
CD007_18060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CD007_18080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CD007_18085	COG1134	teichoic acid transport
CD007_18090	COG1682	transport, permease protein
CD007_18095	COG1215	transferase activity, transferring glycosyl groups
CD007_18095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CD007_18100	COG0463	Glycosyl transferase, family 2
CD007_18145	COG4193	domain, Protein
CD007_18150	COG1482	cell wall glycoprotein biosynthetic process
CD007_18155	COG0697	spore germination
CD007_18160	COG0814	amino acid
CD007_18170	COG2814	Major facilitator Superfamily
CD007_18175	COG1316	TRANSCRIPTIONal
CD007_18180	COG0561	phosphatase activity
CD007_18185	COG0791	NLP P60 protein
CD007_18195	COG2843	Capsule synthesis protein
CD007_18205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CD007_18210	COG1609	Transcriptional regulator
CD007_18215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CD007_18220	COG1869	D-ribose catabolic process
CD007_18225	COG1129	ABC transporter
CD007_18230	COG1172	Belongs to the binding-protein-dependent transport system permease family
CD007_18235	COG1879	ABC-type sugar transport system periplasmic component
CD007_18240	COG3103	Sh3 type 3 domain protein
CD007_18250	COG2249	NAD(P)H dehydrogenase (quinone) activity
CD007_18255	COG3527	Alpha-acetolactate decarboxylase
CD007_18260	COG0028	Belongs to the TPP enzyme family
CD007_18265	COG0583	DNA-binding transcription factor activity
CD007_18270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CD007_18285	COG5337	Spore coat protein CotH
CD007_18295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CD007_18305	COG0405	Gamma-glutamyltransferase
CD007_18310	COG1522	sequence-specific DNA binding
CD007_18315	COG2059	Chromate
CD007_18320	COG2059	Chromate
CD007_18335	COG5444	nuclease activity
CD007_18355	COG3878	Protein conserved in bacteria
CD007_18360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CD007_18365	COG4464	protein tyrosine phosphatase activity
CD007_18370	COG0489	protein tyrosine kinase activity
CD007_18375	COG3944	biosynthesis protein
CD007_18385	COG4715	Zinc finger, swim domain protein
CD007_18390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CD007_18400	COG0561	phosphatase activity
CD007_18405	COG1349	DNA-binding transcription factor activity
CD007_18410	COG0629	single-stranded DNA binding
CD007_18425	COG3764	Sortase (surface protein transpeptidase)
CD007_18435	COG3279	Response regulator of the LytR AlgR family
CD007_18455	COG1970	mechanosensitive ion channel activity
CD007_18460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CD007_18465	COG0457	Tetratricopeptide repeat
CD007_18470	COG4786	Flagellar basal body rod
CD007_18475	COG4786	Flagellar basal body rod
CD007_18480	COG1077	Cell shape determining protein MreB Mrl
CD007_18485	COG1609	Transcriptional regulator
CD007_18495	COG1846	Transcriptional regulator
CD007_18500	COG2814	Major facilitator Superfamily
CD007_18505	COG3420	alginic acid biosynthetic process
CD007_18510	COG1953	Uracil, thiamine, allantoin
CD007_18515	COG0477	Major facilitator Superfamily
CD007_18520	COG1335	isochorismatase
CD007_18530	COG0004	ammonium transporteR
CD007_18535	COG0347	Belongs to the P(II) protein family
CD007_18540	COG0671	phosphoesterase, PA-phosphatase related
CD007_18550	COG0739	heme binding
CD007_18555	COG1247	-acetyltransferase
CD007_18570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CD007_18575	COG0789	Transcriptional regulator
CD007_18585	COG2910	NAD(P)H-binding
CD007_18590	COG1959	2 iron, 2 sulfur cluster binding
CD007_18595	COG0804	urea catabolic process
CD007_18600	COG0832	Belongs to the urease beta subunit family
CD007_18605	COG0831	urea catabolic process
CD007_18620	COG3237	CsbD-like
CD007_18625	COG1994	Peptidase M50
CD007_18630	COG0457	Tetratricopeptide repeat
CD007_18640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CD007_18645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CD007_18655	COG2304	oxidoreductase activity
CD007_18665	COG2304	oxidoreductase activity
CD007_18670	COG2385	sporulation resulting in formation of a cellular spore
CD007_18675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CD007_18685	COG4836	Membrane
CD007_18695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CD007_18700	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CD007_18705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CD007_18710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CD007_18715	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CD007_18720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CD007_18725	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CD007_18730	COG0356	it plays a direct role in the translocation of protons across the membrane
CD007_18740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CD007_18745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CD007_18750	COG4475	Protein of unknown function (DUF436)
CD007_18755	COG0698	ribose 5-phosphate isomerase
CD007_18760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CD007_18765	COG1971	Probably functions as a manganese efflux pump
CD007_18770	COG0009	L-threonylcarbamoyladenylate synthase
CD007_18775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CD007_18795	COG2890	protein-(glutamine-N5) methyltransferase activity
CD007_18800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CD007_18805	COG0346	lactoylglutathione lyase activity
CD007_18810	COG0789	Transcriptional regulator
CD007_18815	COG0679	Auxin Efflux Carrier
CD007_18820	COG0281	malic enzyme
CD007_18825	COG1435	thymidine kinase activity
CD007_18830	COG0254	rRNA binding
CD007_18835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CD007_18840	COG1494	fructose-1,6-bisphosphatase
CD007_18845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CD007_18850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CD007_18855	COG0191	fructose-bisphosphate aldolase activity
CD007_18860	COG2204	response regulator
CD007_18865	COG4821	SIS domain
CD007_18870	COG0504	CTP synthase activity
CD007_18875	COG3343	RNA polymerase activity
CD007_18880	COG1960	acyl-CoA dehydrogenase activity
CD007_18885	COG2181	nitrate reductase activity
CD007_18885	COG0247	lactate metabolic process
CD007_18890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CD007_18895	COG4294	response to UV
CD007_18905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CD007_18910	COG1132	(ABC) transporter
CD007_18915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CD007_18925	COG2181	nitrate reductase activity
CD007_18930	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CD007_18935	COG1140	nitrate reductase beta subunit
CD007_18940	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CD007_18945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CD007_18955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CD007_18960	COG2223	nitrite transmembrane transporter activity
CD007_18965	COG0018	arginyl-trna synthetase
CD007_18970	COG4506	Protein conserved in bacteria
CD007_18985	COG0535	radical SAM domain protein
CD007_18995	COG1131	(ABC) transporter
CD007_19000	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CD007_19005	COG0612	Peptidase, M16
CD007_19010	COG0612	Peptidase, M16
CD007_19020	COG3391	amine dehydrogenase activity
CD007_19025	COG3391	amine dehydrogenase activity
CD007_19035	COG0457	Tetratricopeptide repeat
CD007_19065	COG1131	(ABC) transporter
CD007_19075	COG0010	Belongs to the arginase family
CD007_19080	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CD007_19085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CD007_19100	COG1994	Peptidase M50
CD007_19105	COG1942	4-Oxalocrotonate Tautomerase
CD007_19110	COG1846	Transcriptional regulator
CD007_19115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CD007_19125	COG1959	2 iron, 2 sulfur cluster binding
CD007_19130	COG3465	dGTPase activity
CD007_19135	COG1078	dGTPase activity
CD007_19140	COG4844	belongs to the
CD007_19150	COG0697	spore germination
CD007_19155	COG0095	Lipoate-protein ligase
CD007_19160	COG0583	DNA-binding transcription factor activity
CD007_19165	COG0280	phosphate acetyltransferase
CD007_19175	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_19180	COG0436	Aminotransferase
CD007_19185	COG2814	Major facilitator Superfamily
CD007_19190	COG0151	Belongs to the GarS family
CD007_19195	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_19200	COG1917	Cupin 2, conserved barrel domain protein
CD007_19205	COG0077	Prephenate dehydratase
CD007_19210	COG2814	Major facilitator Superfamily
CD007_19215	COG0833	amino acid
CD007_19220	COG4187	Peptidase family M20/M25/M40
CD007_19225	COG1012	belongs to the aldehyde dehydrogenase family
CD007_19230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CD007_19240	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CD007_19245	COG1091	dTDP-4-dehydrorhamnose reductase activity
CD007_19250	COG1088	dTDP-glucose 4,6-dehydratase activity
CD007_19255	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CD007_19260	COG3980	spore coat polysaccharide biosynthesis protein
CD007_19265	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CD007_19270	COG2089	acid synthase
CD007_19275	COG0456	acetyltransferase
CD007_19280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CD007_19285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CD007_19290	COG0463	Glycosyl transferase, family 2
CD007_19305	COG2363	Small membrane protein
CD007_19310	COG2233	PERMEase
CD007_19320	COG1012	belongs to the aldehyde dehydrogenase family
CD007_19325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CD007_19330	COG1216	Glycosyl transferase, family 2
CD007_19345	COG1695	Transcriptional regulator
CD007_19350	COG0351	phosphomethylpyrimidine kinase
CD007_19360	COG1621	beta-fructofuranosidase activity
CD007_19365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_19365	COG1263	PTS System
CD007_19370	COG2116	formate transmembrane transporter activity
CD007_19375	COG3711	transcriptional antiterminator
CD007_19385	COG1404	Belongs to the peptidase S8 family
CD007_19390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CD007_19395	COG0778	Nitroreductase
CD007_19400	COG0772	Belongs to the SEDS family
CD007_19410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CD007_19415	COG1845	cytochrome c oxidase, subunit III
CD007_19420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CD007_19425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CD007_19430	COG2261	transglycosylase associated protein
CD007_19435	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CD007_19440	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CD007_19445	COG2246	polysaccharide biosynthetic process
CD007_19450	COG1309	transcriptional regulator
CD007_19460	COG3162	membrane
CD007_19465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CD007_19470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CD007_19475	COG2837	iron assimilation
CD007_19480	COG2822	iron ion transport
CD007_19485	COG0672	)-iron permease
CD007_19490	COG0352	thiamine-phosphate diphosphorylase activity
CD007_19495	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CD007_19500	COG0583	DNA-binding transcription factor activity
CD007_19505	COG1380	Effector of murein hydrolase LrgA
CD007_19510	COG1346	cytolysis
CD007_19515	COG2814	Major facilitator Superfamily
CD007_19520	COG4895	conserved protein (DUF2196)
CD007_19525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CD007_19530	COG0346	lactoylglutathione lyase activity
CD007_19545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CD007_19550	COG1404	Belongs to the peptidase S8 family
CD007_19555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_19555	COG1263	PTS System
CD007_19560	COG3711	transcriptional antiterminator
CD007_19565	COG1442	glycosyl transferase family 8
CD007_19570	COG5522	Integral membrane protein (intg_mem_TP0381)
CD007_19575	COG1846	Transcriptional regulator
CD007_19580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CD007_19585	COG2234	aminopeptidase activity
CD007_19600	COG2814	Major facilitator Superfamily
CD007_19605	COG2357	RelA SpoT domain protein
CD007_19610	COG1575	Belongs to the MenA family. Type 1 subfamily
CD007_19625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CD007_19630	COG1696	Membrane protein involved in D-alanine export
CD007_19635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CD007_19640	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CD007_19645	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CD007_19650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CD007_19655	COG1486	melibiose metabolic process
CD007_19660	COG1447	Phosphotransferase system cellobiose-specific component IIA
CD007_19665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CD007_19670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CD007_19675	COG3711	transcriptional antiterminator
CD007_19675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CD007_19685	COG2094	Belongs to the DNA glycosylase MPG family
CD007_19690	COG0753	catalase activity
CD007_19695	COG2814	Major facilitator Superfamily
CD007_19700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CD007_19705	COG1131	(ABC) transporter
CD007_19725	COG1595	DNA-templated transcription, initiation
CD007_19730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CD007_19735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CD007_19740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CD007_19745	COG4988	ABC transporter
CD007_19750	COG1294	oxidase, subunit
CD007_19755	COG1271	oxidase subunit
CD007_19760	COG3493	citrate carrier protein
CD007_19765	COG0501	Belongs to the peptidase M48B family
CD007_19775	COG0726	polysaccharide deacetylase
CD007_19790	COG3842	ATPase activity
CD007_19795	COG2508	Transcriptional regulator
CD007_19800	COG1012	belongs to the aldehyde dehydrogenase family
CD007_19805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CD007_19815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CD007_19820	COG1881	PFAM PEBP family protein
CD007_19825	COG0583	DNA-binding transcription factor activity
CD007_19835	COG4585	Histidine kinase
CD007_19840	COG2197	response regulator
CD007_19845	COG2195	Cleaves the N-terminal amino acid of tripeptides
CD007_19855	COG4894	glucomannan catabolic process
CD007_19860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CD007_19865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CD007_19870	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_19875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CD007_19880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CD007_19885	COG2610	gluconate transmembrane transporter activity
CD007_19890	COG0500	methyltransferase
CD007_19895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CD007_19910	COG0753	catalase activity
CD007_19910	COG0693	protein deglycase activity
CD007_19915	COG2851	Citrate transporter
CD007_19920	COG2273	Hydrolase Family 16
CD007_19925	COG3711	transcriptional antiterminator
CD007_19935	COG2270	Major facilitator Superfamily
CD007_19940	COG0513	Belongs to the DEAD box helicase family
CD007_19945	COG3401	FG-GAP repeat protein
CD007_19945	COG2755	lipolytic protein G-D-S-L family
CD007_19990	COG3209	COG3209 Rhs family protein
CD007_19995	COG0697	spore germination
CD007_20000	COG0589	response to stress
CD007_20005	COG2723	6-phospho-beta-galactosidase activity
CD007_20010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_20010	COG2190	(PTS) system
CD007_20010	COG1263	PTS System
CD007_20055	COG3507	Belongs to the glycosyl hydrolase 43 family
CD007_20065	COG2986	histidine ammonia-lyase
CD007_20070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CD007_20075	COG1228	amidohydrolase
CD007_20080	COG0010	Belongs to the arginase family
CD007_20085	COG0833	amino acid
CD007_20090	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CD007_20095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CD007_20100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CD007_20105	COG2390	Transcriptional regulator
CD007_20115	COG3192	ethanolamine utilization protein
CD007_20120	COG2079	MmgE PrpD family protein
CD007_20130	COG1126	abc transporter atp-binding protein
CD007_20135	COG0765	amino acid transport
CD007_20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CD007_20155	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CD007_20160	COG0561	phosphatase activity
CD007_20190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CD007_20195	COG5294	Protein conserved in bacteria
CD007_20200	COG0577	efflux transmembrane transporter activity
CD007_20205	COG1136	(ABC) transporter
CD007_20210	COG2205	protein histidine kinase activity
CD007_20215	COG0745	RESPONSE REGULATOR receiver
CD007_20220	COG0191	fructose-bisphosphate aldolase activity
CD007_20225	COG1082	Xylose isomerase domain protein TIM barrel
CD007_20230	COG1082	Xylose isomerase domain protein TIM barrel
CD007_20235	COG0673	inositol 2-dehydrogenase activity
CD007_20240	COG2814	Major facilitator Superfamily
CD007_20245	COG1082	Xylose isomerase domain protein TIM barrel
CD007_20250	COG3962	Belongs to the TPP enzyme family
CD007_20255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CD007_20265	COG1012	belongs to the aldehyde dehydrogenase family
CD007_20270	COG1349	DNA-binding transcription factor activity
CD007_20275	COG0667	Aldo Keto reductase
CD007_20290	COG2814	Major facilitator Superfamily
CD007_20295	COG0326	Molecular chaperone. Has ATPase activity
CD007_20305	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_20335	COG1309	transcriptional regulator
CD007_20340	COG1012	belongs to the aldehyde dehydrogenase family
CD007_20345	COG1714	RDD family
CD007_20350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CD007_20360	COG1714	RDD family
CD007_20365	COG2311	Membrane
CD007_20370	COG1917	Cupin 2, conserved barrel domain protein
CD007_20375	COG1309	transcriptional regulator
CD007_20380	COG1028	Short-chain dehydrogenase reductase Sdr
CD007_20385	COG1846	Transcriptional regulator
CD007_20390	COG1380	Effector of murein hydrolase LrgA
CD007_20395	COG1346	cytolysis
CD007_20400	COG5039	Polysaccharide pyruvyl transferase
CD007_20405	COG1929	Belongs to the glycerate kinase type-1 family
CD007_20410	COG1802	Transcriptional regulator
CD007_20415	COG1070	Carbohydrate kinase
CD007_20420	COG2610	gluconate transmembrane transporter activity
CD007_20425	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CD007_20430	COG0450	alkyl hydroperoxide reductase
CD007_20435	COG3634	alkyl hydroperoxide reductase activity
CD007_20455	COG1263	PTS System
CD007_20455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CD007_20460	COG2188	Transcriptional regulator
CD007_20475	COG1131	(ABC) transporter
CD007_20480	COG1994	Peptidase M50
CD007_20485	COG0535	radical SAM domain protein
CD007_20495	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CD007_20505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CD007_20520	COG1063	alcohol dehydrogenase
CD007_20540	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CD007_20545	COG0456	acetyltransferase
CD007_20550	COG0457	Tetratricopeptide repeat
CD007_20560	COG0010	Belongs to the arginase family
CD007_20565	COG0833	amino acid
CD007_20570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CD007_20575	COG3829	transcription factor binding
CD007_20580	COG5002	protein histidine kinase activity
CD007_20585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CD007_20590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CD007_20595	COG4853	Protein conserved in bacteria
CD007_20600	COG4863	YycH protein
CD007_20605	COG5002	protein histidine kinase activity
CD007_20610	COG0745	RESPONSE REGULATOR receiver
CD007_20640	COG0346	lactoylglutathione lyase activity
CD007_20645	COG0305	Participates in initiation and elongation during chromosome replication
CD007_20660	COG3093	addiction module antidote protein HigA
CD007_20665	COG2807	transmembrane transport
CD007_20670	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CD007_20675	COG0359	binds to the 23S rRNA
CD007_20680	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CD007_20685	COG4241	membrane
CD007_20695	COG5577	PFAM Coat F domain
CD007_20700	COG1733	regulation of RNA biosynthetic process
CD007_20705	COG1227	inorganic diphosphatase activity
CD007_20720	COG2271	Major facilitator Superfamily
CD007_20725	COG4978	Transcriptional regulator
CD007_20725	COG0789	Transcriptional regulator
CD007_20735	COG4319	ketosteroid isomerase
CD007_20740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CD007_20745	COG1846	Transcriptional regulator
CD007_20750	COG2153	protein acetylation
CD007_20755	COG2364	Membrane
CD007_20760	COG0456	acetyltransferase
CD007_20765	COG2315	Protein conserved in bacteria
CD007_20770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CD007_20785	COG0789	Transcriptional regulator
CD007_20790	COG0697	spore germination
CD007_20795	COG1331	Highly conserved protein containing a thioredoxin domain
CD007_20800	COG1266	CAAX protease self-immunity
CD007_20805	COG2814	Major facilitator Superfamily
CD007_20805	COG0477	Major facilitator Superfamily
CD007_20810	COG0110	maltose O-acetyltransferase activity
CD007_20815	COG0346	lactoylglutathione lyase activity
CD007_20820	COG1609	Transcriptional regulator
CD007_20825	COG0708	Exodeoxyribonuclease III
CD007_20830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CD007_20835	COG0629	single-stranded DNA binding
CD007_20840	COG0360	Binds together with S18 to 16S ribosomal RNA
CD007_20845	COG0012	GTP binding
CD007_20850	COG0243	molybdopterin cofactor binding
CD007_20855	COG4481	Protein conserved in bacteria
CD007_20860	COG3949	Membrane
CD007_20870	COG1475	DNA binding
CD007_20875	COG1192	Involved in chromosome partitioning
CD007_20885	COG1475	DNA binding
CD007_20890	COG0357	Ribosomal RNA small subunit methyltransferase G
CD007_20895	COG0445	tRNA wobble uridine modification
CD007_20900	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CD007_20905	COG1847	R3H domain protein
CD007_20910	COG0706	membrane insertase activity
CD007_20915	COG0594	ribonuclease P activity
CD007_20920	COG0230	Belongs to the bacterial ribosomal protein bL34 family