locus-tag	class	description
JOW61_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JOW61_00010	COG0592	DNA-directed DNA polymerase activity
JOW61_00015	COG2501	S4 domain
JOW61_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JOW61_00030	COG0187	DNA topoisomerase II activity
JOW61_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOW61_00070	COG0516	GMP reductase activity
JOW61_00070	COG0517	IMP dehydrogenase activity
JOW61_00075	COG1686	Belongs to the peptidase S11 family
JOW61_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JOW61_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JOW61_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JOW61_00100	COG1428	Deoxynucleoside kinase
JOW61_00105	COG1428	Deoxynucleoside kinase
JOW61_00110	COG1388	LysM domain
JOW61_00110	COG3858	chitin binding
JOW61_00115	COG1335	isochorismatase
JOW61_00120	COG0590	tRNA wobble adenosine to inosine editing
JOW61_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOW61_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JOW61_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JOW61_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JOW61_00190	COG3853	Toxic anion resistance protein (TelA)
JOW61_00195	COG1982	Orn Lys Arg decarboxylase major
JOW61_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JOW61_00205	COG3870	Protein conserved in bacteria
JOW61_00210	COG1728	Protein conserved in bacteria
JOW61_00215	COG0470	DNA polymerase III
JOW61_00220	COG1774	PSP1 C-terminal conserved region
JOW61_00225	COG4467	Involved in initiation control of chromosome replication
JOW61_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JOW61_00235	COG2827	Endonuclease containing a URI domain
JOW61_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JOW61_00245	COG2002	toxin-antitoxin pair type II binding
JOW61_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOW61_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOW61_00255	COG0084	hydrolase, TatD family'
JOW61_00260	COG3583	domain protein
JOW61_00260	COG3584	3D domain protein
JOW61_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JOW61_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JOW61_00280	COG4466	Protein conserved in bacteria
JOW61_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JOW61_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOW61_00300	COG0251	oxidation-reduction process
JOW61_00305	COG2088	sporulation resulting in formation of a cellular spore
JOW61_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JOW61_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOW61_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JOW61_00325	COG0193	aminoacyl-tRNA hydrolase activity
JOW61_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOW61_00340	COG2002	toxin-antitoxin pair type II binding
JOW61_00345	COG2244	polysaccharide biosynthetic process
JOW61_00350	COG3956	TIGRFAM MazG family protein
JOW61_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JOW61_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JOW61_00375	COG1098	S1 RNA binding domain
JOW61_00390	COG2208	phosphoserine phosphatase activity
JOW61_00395	COG2304	oxidoreductase activity
JOW61_00400	COG0515	serine threonine protein kinase
JOW61_00405	COG0037	tRNA processing
JOW61_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JOW61_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOW61_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JOW61_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOW61_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JOW61_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JOW61_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOW61_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
JOW61_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JOW61_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JOW61_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JOW61_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JOW61_00470	COG1396	sequence-specific DNA binding
JOW61_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOW61_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JOW61_00560	COG4463	regulation of RNA biosynthetic process
JOW61_00565	COG3880	PFAM UvrB UvrC protein
JOW61_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JOW61_00575	COG0542	response to heat
JOW61_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JOW61_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JOW61_00590	COG4956	integral membrane protein (PIN domain superfamily)
JOW61_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JOW61_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JOW61_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JOW61_00610	COG1045	serine acetyltransferase
JOW61_00615	COG0215	cysteine-tRNA ligase activity
JOW61_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JOW61_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOW61_00630	COG3688	RNA-binding protein containing a PIN domain
JOW61_00635	COG1595	DNA-templated transcription, initiation
JOW61_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JOW61_00650	COG0250	Participates in transcription elongation, termination and antitermination
JOW61_00660	COG0081	regulation of translation
JOW61_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JOW61_00675	COG2813	Specifically methylates the guanine in position
JOW61_00680	COG0085	RNA polymerase activity
JOW61_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOW61_00690	COG1358	cellular component organization or biogenesis
JOW61_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JOW61_00700	COG0049	tRNA binding
JOW61_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JOW61_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JOW61_00715	COG0596	Alpha beta hydrolase
JOW61_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JOW61_00730	COG0088	Forms part of the polypeptide exit tunnel
JOW61_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOW61_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JOW61_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JOW61_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JOW61_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JOW61_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JOW61_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JOW61_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JOW61_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JOW61_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JOW61_00820	COG0200	Binds to the 23S rRNA
JOW61_00825	COG0201	protein transport
JOW61_00830	COG0563	adenylate kinase activity
JOW61_00835	COG0024	Methionine aminopeptidase
JOW61_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JOW61_00855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JOW61_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JOW61_00865	COG0202	RNA polymerase activity
JOW61_00870	COG0203	ribosomal protein L17
JOW61_00875	COG1122	ATPase activity
JOW61_00880	COG1122	ATPase activity
JOW61_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOW61_00890	COG0101	tRNA pseudouridine synthase activity
JOW61_00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JOW61_00900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JOW61_00905	COG2226	methyltransferase
JOW61_00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOW61_00920	COG0489	protein tyrosine kinase activity
JOW61_00930	COG2194	sulfuric ester hydrolase activity
JOW61_00935	COG0726	polysaccharide deacetylase
JOW61_01015	COG0659	secondary active sulfate transmembrane transporter activity
JOW61_01020	COG0385	Bile acid
JOW61_01025	COG2819	hydrolase of the alpha beta superfamily
JOW61_01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JOW61_01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JOW61_01045	COG2207	Transcriptional regulator
JOW61_01050	COG3876	Protein conserved in bacteria
JOW61_01055	COG1472	Belongs to the glycosyl hydrolase 3 family
JOW61_01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JOW61_01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_01065	COG1263	PTS System
JOW61_01070	COG1737	Transcriptional regulator
JOW61_01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JOW61_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_01085	COG1683	Conserved Protein
JOW61_01115	COG1595	DNA-templated transcription, initiation
JOW61_01120	COG5662	AntiSigma factor
JOW61_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOW61_01130	COG4856	YbbR-like protein
JOW61_01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOW61_01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JOW61_01155	COG2169	Transcriptional regulator
JOW61_01160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOW61_01165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JOW61_01170	COG3002	Belongs to the UPF0753 family
JOW61_01175	COG0288	reversible hydration of carbon dioxide
JOW61_01185	COG5609	conserved protein (DUF2294)
JOW61_01195	COG0642	Histidine kinase
JOW61_01205	COG0515	serine threonine protein kinase
JOW61_01220	COG1113	amino acid transport
JOW61_01235	COG2602	Beta-lactamase
JOW61_01240	COG2124	cytochrome p450
JOW61_01250	COG0531	amino acid
JOW61_01255	COG0584	glycerophosphoryl diester phosphodiesterase
JOW61_01260	COG2271	Major facilitator Superfamily
JOW61_01270	COG0456	acetyltransferase
JOW61_01270	COG1846	Transcriptional regulator
JOW61_01285	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_01290	COG0697	spore germination
JOW61_01295	COG1917	Cupin 2, conserved barrel domain protein
JOW61_01295	COG2207	Transcriptional regulator
JOW61_01320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JOW61_01325	COG3591	Belongs to the peptidase S1B family
JOW61_01335	COG0596	Alpha beta hydrolase
JOW61_01340	COG1183	phosphatidylcholine synthase activity
JOW61_01345	COG0586	Pfam SNARE associated Golgi protein
JOW61_01350	COG0688	phosphatidylethanolamine metabolic process
JOW61_01360	COG2312	Erythromycin esterase
JOW61_01365	COG2207	Transcriptional regulator
JOW61_01370	COG1054	Belongs to the UPF0176 family
JOW61_01375	COG1301	dicarboxylic acid transport
JOW61_01380	COG1263	PTS System
JOW61_01380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_01380	COG2190	(PTS) system
JOW61_01385	COG0363	glucosamine-6-phosphate deaminase activity
JOW61_01390	COG2188	Transcriptional regulator
JOW61_01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JOW61_01405	COG0833	amino acid
JOW61_01410	COG2040	homocysteine
JOW61_01420	COG2066	Belongs to the glutaminase family
JOW61_01425	COG4191	Histidine kinase
JOW61_01430	COG0784	Response regulator, receiver
JOW61_01435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOW61_01440	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_01445	COG2271	Major facilitator Superfamily
JOW61_01450	COG4948	Mandelate Racemase Muconate Lactonizing
JOW61_01455	COG2186	Transcriptional regulator
JOW61_01460	COG2721	sulfolactate sulfo-lyase activity
JOW61_01465	COG3173	Aminoglycoside phosphotransferase
JOW61_01475	COG0697	spore germination
JOW61_01480	COG0745	RESPONSE REGULATOR receiver
JOW61_01485	COG2205	protein histidine kinase activity
JOW61_01490	COG1131	(ABC) transporter
JOW61_01510	COG3773	Cell wall hydrolase
JOW61_01515	COG2304	oxidoreductase activity
JOW61_01525	COG3540	Alkaline phosphatase
JOW61_01530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOW61_01535	COG0805	protein transport
JOW61_01540	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JOW61_01545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOW61_01550	COG0477	Major facilitator Superfamily
JOW61_01555	COG1309	transcriptional regulator
JOW61_01560	COG0252	asparaginase activity
JOW61_01565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JOW61_01570	COG1714	RDD family
JOW61_01575	COG1405	negative regulation of cell septum assembly
JOW61_01575	COG3012	SEC-C Motif Domain Protein
JOW61_01585	COG3279	Response regulator of the LytR AlgR family
JOW61_01595	COG1668	transmembrane transport
JOW61_01600	COG0667	Aldo Keto reductase
JOW61_01615	COG1595	DNA-templated transcription, initiation
JOW61_01620	COG1595	DNA-templated transcription, initiation
JOW61_01625	COG1876	peptidase activity
JOW61_01635	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_01640	COG0366	Alpha amylase catalytic
JOW61_01645	COG0803	Belongs to the bacterial solute-binding protein 9 family
JOW61_01650	COG1121	(ABC) transporter
JOW61_01655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JOW61_01665	COG2310	stress, protein
JOW61_01670	COG2310	stress, protein
JOW61_01675	COG2310	stress, protein
JOW61_01680	COG0861	Integral membrane protein TerC family
JOW61_01690	COG3853	Toxic anion resistance protein (TelA)
JOW61_01700	COG0477	Major facilitator Superfamily
JOW61_01705	COG2814	Major facilitator Superfamily
JOW61_01710	COG0640	Transcriptional regulator
JOW61_01715	COG0517	IMP dehydrogenase activity
JOW61_01715	COG4175	Glycine betaine
JOW61_01720	COG4176	ABC-type proline glycine betaine transport system permease component
JOW61_01725	COG2113	Glycine betaine
JOW61_01730	COG1473	amidohydrolase
JOW61_01735	COG1288	antiporter activity
JOW61_01750	COG0039	L-malate dehydrogenase activity
JOW61_01765	COG3403	YqcI/YcgG family
JOW61_01780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JOW61_01785	COG1660	Displays ATPase and GTPase activities
JOW61_01790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JOW61_01800	COG2226	methyltransferase
JOW61_01805	COG0583	DNA-binding transcription factor activity
JOW61_01810	COG3458	cephalosporin-C deacetylase activity
JOW61_01815	COG3541	Predicted nucleotidyltransferase
JOW61_01820	COG0506	proline dehydrogenase activity
JOW61_01825	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_01830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOW61_01835	COG2508	Transcriptional regulator
JOW61_01840	COG3689	TIGRFAM TIGR03943 family protein
JOW61_01845	COG0701	Predicted permease
JOW61_01850	COG2267	carboxylic ester hydrolase activity
JOW61_01855	COG0492	ferredoxin-NADP+ reductase activity
JOW61_01860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JOW61_01860	COG1587	Uroporphyrinogen-III synthase
JOW61_01865	COG2146	nitrite reductase [NAD(P)H] activity
JOW61_01870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOW61_01875	COG0243	molybdopterin cofactor binding
JOW61_01880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOW61_01885	COG2223	nitrite transmembrane transporter activity
JOW61_01895	COG1376	ErfK ybiS ycfS ynhG family protein
JOW61_01910	COG0765	amino acid transport
JOW61_01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JOW61_01925	COG1714	RDD family
JOW61_01935	COG1846	Transcriptional regulator
JOW61_01950	COG2723	6-phospho-beta-galactosidase activity
JOW61_01960	COG3209	COG3209 Rhs family protein
JOW61_01970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JOW61_01975	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JOW61_01980	COG1733	regulation of RNA biosynthetic process
JOW61_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JOW61_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JOW61_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JOW61_02000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JOW61_02005	COG2814	Major facilitator Superfamily
JOW61_02015	COG0697	spore germination
JOW61_02020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOW61_02030	COG2364	Membrane
JOW61_02035	COG1126	abc transporter atp-binding protein
JOW61_02040	COG0765	amino acid transport
JOW61_02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JOW61_02050	COG0583	DNA-binding transcription factor activity
JOW61_02055	COG0163	prenyltransferase activity
JOW61_02060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JOW61_02075	COG0596	Alpha beta hydrolase
JOW61_02080	COG3104	oligopeptide transport
JOW61_02085	COG5434	Belongs to the glycosyl hydrolase 28 family
JOW61_02095	COG0697	spore germination
JOW61_02105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JOW61_02110	COG1136	(ABC) transporter
JOW61_02115	COG0577	efflux transmembrane transporter activity
JOW61_02120	COG0745	RESPONSE REGULATOR receiver
JOW61_02125	COG5002	protein histidine kinase activity
JOW61_02125	COG3850	Histidine kinase
JOW61_02130	COG0457	Tetratricopeptide repeat
JOW61_02150	COG0527	aspartate kinase activity
JOW61_02155	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_02160	COG4605	iron ion homeostasis
JOW61_02165	COG4604	ABC transporter, ATP-binding protein
JOW61_02170	COG4607	ABC-type enterochelin transport system periplasmic component
JOW61_02180	COG2814	Major facilitator Superfamily
JOW61_02185	COG1309	transcriptional regulator
JOW61_02190	COG0778	Nitroreductase
JOW61_02195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JOW61_02200	COG0640	Transcriptional regulator
JOW61_02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOW61_02210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOW61_02215	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_02220	COG4975	Glucose uptake
JOW61_02225	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_02230	COG4549	nuclear export factor GLE1
JOW61_02235	COG2372	response to copper ion
JOW61_02235	COG1276	copper resistance
JOW61_02240	COG1349	DNA-binding transcription factor activity
JOW61_02250	COG2213	PTS system mannitol-specific
JOW61_02255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_02260	COG0246	Mannitol dehydrogenase
JOW61_02265	COG0473	3-isopropylmalate dehydrogenase activity
JOW61_02270	COG0681	Belongs to the peptidase S26 family
JOW61_02280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JOW61_02290	COG0561	phosphatase activity
JOW61_02295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JOW61_02300	COG1914	H( )-stimulated, divalent metal cation uptake system
JOW61_02305	COG4336	lyase activity
JOW61_02310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JOW61_02315	COG1984	allophanate hydrolase subunit 2
JOW61_02320	COG1414	Transcriptional regulator
JOW61_02325	COG2755	lipolytic protein G-D-S-L family
JOW61_02335	COG2329	Antibiotic biosynthesis monooxygenase
JOW61_02340	COG0768	penicillin binding
JOW61_02345	COG4989	oxidoreductase activity
JOW61_02350	COG3711	transcriptional antiterminator
JOW61_02355	COG0318	PFAM AMP-dependent synthetase and ligase
JOW61_02360	COG2226	methyltransferase
JOW61_02365	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_02370	COG1917	Cupin 2, conserved barrel domain protein
JOW61_02375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_02380	COG3871	stress protein (general stress protein 26)
JOW61_02390	COG2814	Major facilitator Superfamily
JOW61_02395	COG1522	sequence-specific DNA binding
JOW61_02400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOW61_02400	COG0551	DNA topoisomerase type I activity
JOW61_02405	COG0494	nUDIX hydrolase
JOW61_02410	COG0028	Belongs to the TPP enzyme family
JOW61_02435	COG1914	H( )-stimulated, divalent metal cation uptake system
JOW61_02440	COG2261	transglycosylase associated protein
JOW61_02445	COG4876	unkown
JOW61_02450	COG2217	Heavy metal translocating P-type atpase
JOW61_02455	COG3729	General stress protein
JOW61_02460	COG0662	Cupin 2, conserved barrel domain protein
JOW61_02465	COG2329	Antibiotic biosynthesis monooxygenase
JOW61_02470	COG3546	catalase activity
JOW61_02475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JOW61_02480	COG3290	protein histidine kinase activity
JOW61_02485	COG4565	transcriptional regulatory protein
JOW61_02490	COG1301	dicarboxylic acid transport
JOW61_02495	COG0628	permease
JOW61_02505	COG1131	(ABC) transporter
JOW61_02510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JOW61_02520	COG1960	acyl-CoA dehydrogenase activity
JOW61_02535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOW61_02540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_02545	COG1181	Belongs to the D-alanine--D-alanine ligase family
JOW61_02550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JOW61_02555	COG0513	Belongs to the DEAD box helicase family
JOW61_02560	COG3402	PFAM membrane-flanked domain
JOW61_02565	COG3428	Bacterial PH domain
JOW61_02570	COG0705	Rhomboid family
JOW61_02575	COG0736	holo-[acyl-carrier-protein] synthase activity
JOW61_02580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JOW61_02585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOW61_02590	COG0864	Transcriptional regulator
JOW61_02595	COG2337	Toxic component of a toxin-antitoxin (TA) module
JOW61_02600	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_02610	COG2172	sigma factor antagonist activity
JOW61_02615	COG2208	phosphoserine phosphatase activity
JOW61_02620	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_02625	COG2172	sigma factor antagonist activity
JOW61_02630	COG1191	sigma factor activity
JOW61_02635	COG2208	phosphoserine phosphatase activity
JOW61_02650	COG1673	EVE domain
JOW61_02655	COG1846	Transcriptional regulator
JOW61_02660	COG2183	response to ionizing radiation
JOW61_02670	COG3091	SprT-like family
JOW61_02710	COG0582	viral genome integration into host DNA
JOW61_02715	COG2856	Zn peptidase
JOW61_02720	COG1396	sequence-specific DNA binding
JOW61_02750	COG1674	ftsk spoiiie
JOW61_02755	COG2946	Replication initiation factor
JOW61_02795	COG0433	COG0433 Predicted ATPase
JOW61_02805	COG5644	endopeptidase inhibitor activity
JOW61_02815	COG0741	lytic transglycosylase activity
JOW61_02815	COG0791	NLP P60 protein
JOW61_02830	COG0457	Tetratricopeptide repeat
JOW61_02860	COG0583	DNA-binding transcription factor activity
JOW61_02865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_02875	COG5444	nuclease activity
JOW61_02880	COG1476	TRANSCRIPTIONal
JOW61_02900	COG0693	protein deglycase activity
JOW61_02905	COG1278	Cold shock
JOW61_02910	COG1329	Transcriptional regulator
JOW61_02915	COG0697	spore germination
JOW61_02920	COG1917	Cupin 2, conserved barrel domain protein
JOW61_02920	COG2207	Transcriptional regulator
JOW61_02930	COG2207	Transcriptional regulator
JOW61_02930	COG3708	Transcriptional regulator
JOW61_02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOW61_02950	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JOW61_02965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_02970	COG1309	transcriptional regulator
JOW61_02975	COG0697	spore germination
JOW61_02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOW61_02985	COG2030	dehydratase
JOW61_02990	COG3545	Serine hydrolase
JOW61_03000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOW61_03005	COG0640	Transcriptional regulator
JOW61_03010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOW61_03020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_03025	COG0697	spore germination
JOW61_03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOW61_03035	COG0076	glutamate decarboxylase activity
JOW61_03040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JOW61_03045	COG0640	Transcriptional regulator
JOW61_03050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOW61_03065	COG4585	Histidine kinase
JOW61_03070	COG2197	response regulator
JOW61_03075	COG2409	Drug exporters of the RND superfamily
JOW61_03080	COG0596	Alpha beta hydrolase
JOW61_03085	COG1811	Na channel or pump
JOW61_03090	COG0789	Transcriptional regulator
JOW61_03090	COG4978	Transcriptional regulator
JOW61_03095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOW61_03100	COG0778	Nitroreductase
JOW61_03105	COG0346	lactoylglutathione lyase activity
JOW61_03110	COG2259	Doxx family
JOW61_03115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_03140	COG2323	membrane
JOW61_03145	COG0071	Belongs to the small heat shock protein (HSP20) family
JOW61_03160	COG1309	transcriptional regulator
JOW61_03170	COG0456	acetyltransferase
JOW61_03175	COG0488	(ABC) transporter
JOW61_03180	COG1113	amino acid transport
JOW61_03185	COG2318	DinB family
JOW61_03190	COG1846	Transcriptional regulator
JOW61_03195	COG2409	Drug exporters of the RND superfamily
JOW61_03195	COG1033	growth of symbiont in host cell
JOW61_03200	COG0778	Nitroreductase
JOW61_03205	COG1846	Transcriptional regulator
JOW61_03210	COG2814	Major facilitator Superfamily
JOW61_03215	COG0730	response to heat
JOW61_03220	COG1802	Transcriptional regulator
JOW61_03225	COG1388	LysM domain
JOW61_03225	COG3858	chitin binding
JOW61_03230	COG1819	glycosyl
JOW61_03240	COG1785	Belongs to the alkaline phosphatase family
JOW61_03245	COG5646	InterPro IPR014922
JOW61_03255	COG0454	-acetyltransferase
JOW61_03260	COG1078	dGTPase activity
JOW61_03265	COG1388	LysM domain
JOW61_03270	COG2814	Major facilitator Superfamily
JOW61_03275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JOW61_03290	COG2723	6-phospho-beta-galactosidase activity
JOW61_03295	COG2188	Transcriptional regulator
JOW61_03300	COG1940	carbohydrate kinase activity
JOW61_03310	COG4124	Belongs to the glycosyl hydrolase 26 family
JOW61_03355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JOW61_03360	COG0802	atpase or kinase
JOW61_03365	COG1214	PFAM Peptidase M22, glycoprotease
JOW61_03370	COG0456	acetyltransferase
JOW61_03375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JOW61_03380	COG0488	(ABC) transporter
JOW61_03385	COG0315	cyclic pyranopterin monophosphate synthase activity
JOW61_03390	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JOW61_03395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOW61_03400	COG0805	protein transport
JOW61_03410	COG1266	CAAX protease self-immunity
JOW61_03420	COG0459	protein refolding
JOW61_03440	COG0457	Tetratricopeptide repeat
JOW61_03445	COG1063	alcohol dehydrogenase
JOW61_03450	COG2211	Major facilitator Superfamily
JOW61_03455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOW61_03465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOW61_03470	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JOW61_03475	COG4260	virion core protein, lumpy skin disease virus
JOW61_03485	COG2814	Major facilitator Superfamily
JOW61_03490	COG1063	alcohol dehydrogenase
JOW61_03495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JOW61_03500	COG0823	Involved in the tonB-independent uptake of proteins
JOW61_03520	COG2267	carboxylic ester hydrolase activity
JOW61_03530	COG2132	Multicopper oxidase
JOW61_03535	COG1113	amino acid transport
JOW61_03545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOW61_03550	COG0714	Associated with various cellular activities
JOW61_03555	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JOW61_03560	COG1305	Transglutaminase-like
JOW61_03565	COG0519	Catalyzes the synthesis of GMP from XMP
JOW61_03565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JOW61_03575	COG2252	PERMEase
JOW61_03580	COG3064	Membrane
JOW61_03590	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JOW61_03600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JOW61_03605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JOW61_03610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JOW61_03615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JOW61_03620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOW61_03625	COG0047	phosphoribosylformylglycinamidine synthase activity
JOW61_03630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOW61_03635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JOW61_03640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JOW61_03645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JOW61_03650	COG0138	bifunctional purine biosynthesis protein purh
JOW61_03655	COG0151	Belongs to the GarS family
JOW61_03660	COG1522	sequence-specific DNA binding
JOW61_03665	COG0531	amino acid
JOW61_03675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JOW61_03680	COG1470	cell adhesion involved in biofilm formation
JOW61_03685	COG4496	protein, YerC YecD
JOW61_03690	COG0069	glutamate synthase activity
JOW61_03695	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JOW61_03700	COG0210	DNA helicase
JOW61_03705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JOW61_03710	COG4851	CamS sex pheromone cAM373 precursor
JOW61_03720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOW61_03725	COG1285	pathogenesis
JOW61_03730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOW61_03735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOW61_03740	COG0154	amidase activity
JOW61_03745	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOW61_03750	COG1309	transcriptional regulator
JOW61_03755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOW61_03760	COG1597	lipid kinase activity
JOW61_03765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOW61_03795	COG5444	nuclease activity
JOW61_03805	COG0457	Tetratricopeptide repeat
JOW61_03815	COG0217	transcriptional regulatory protein
JOW61_03825	COG1309	transcriptional regulator
JOW61_03840	COG3546	catalase activity
JOW61_03845	COG0454	-acetyltransferase
JOW61_03855	COG5578	integral membrane protein
JOW61_03860	COG2972	Histidine kinase
JOW61_03870	COG1653	transport
JOW61_03875	COG1175	transmembrane transport
JOW61_03880	COG0395	ABC-type sugar transport system, permease component
JOW61_03885	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JOW61_03890	COG2207	Transcriptional regulator
JOW61_03895	COG2755	lipolytic protein G-D-S-L family
JOW61_03905	COG5578	integral membrane protein
JOW61_03910	COG3401	FG-GAP repeat protein
JOW61_03915	COG3401	FG-GAP repeat protein
JOW61_03920	COG2755	lipolytic protein G-D-S-L family
JOW61_03935	COG1653	transport
JOW61_03940	COG4209	transmembrane transport
JOW61_03945	COG0395	ABC-type sugar transport system, permease component
JOW61_03950	COG1486	melibiose metabolic process
JOW61_03955	COG2323	membrane
JOW61_03960	COG2329	Antibiotic biosynthesis monooxygenase
JOW61_03965	COG0346	lactoylglutathione lyase activity
JOW61_03980	COG5583	Uncharacterized small protein (DUF2292)
JOW61_03985	COG0670	Belongs to the BI1 family
JOW61_03990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOW61_04000	COG3328	transposase activity
JOW61_04010	COG2124	cytochrome p450
JOW61_04010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOW61_04015	COG1368	sulfuric ester hydrolase activity
JOW61_04020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JOW61_04025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JOW61_04030	COG1442	glycosyl transferase family 8
JOW61_04035	COG1216	Glycosyl transferase, family 2
JOW61_04040	COG1442	glycosyl transferase family 8
JOW61_04045	COG2223	nitrite transmembrane transporter activity
JOW61_04050	COG1011	Hydrolase
JOW61_04055	COG0531	amino acid
JOW61_04060	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_04065	COG0840	transmembrane signaling receptor activity
JOW61_04070	COG0488	(ABC) transporter
JOW61_04080	COG0789	Transcriptional regulator
JOW61_04085	COG2814	Major facilitator Superfamily
JOW61_04100	COG0488	(ABC) transporter
JOW61_04105	COG0513	Belongs to the DEAD box helicase family
JOW61_04115	COG3866	Pectate lyase
JOW61_04120	COG0471	metal ion transport
JOW61_04125	COG3290	protein histidine kinase activity
JOW61_04130	COG4565	transcriptional regulatory protein
JOW61_04135	COG3181	Tripartite tricarboxylate transporter family receptor
JOW61_04140	COG2851	Citrate transporter
JOW61_04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOW61_04150	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JOW61_04155	COG1254	Belongs to the acylphosphatase family
JOW61_04160	COG2258	MOSC domain
JOW61_04180	COG0024	Methionine aminopeptidase
JOW61_04185	COG1263	PTS System
JOW61_04185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_04190	COG1368	sulfuric ester hydrolase activity
JOW61_04205	COG1115	amino acid carrier protein
JOW61_04220	COG0697	spore germination
JOW61_04225	COG1263	PTS System
JOW61_04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_04230	COG0366	Alpha amylase catalytic
JOW61_04235	COG2188	Transcriptional regulator
JOW61_04240	COG0778	Nitroreductase
JOW61_04245	COG0737	Belongs to the 5'-nucleotidase family
JOW61_04250	COG0693	protein deglycase activity
JOW61_04260	COG2814	Major facilitator Superfamily
JOW61_04265	COG4840	Belongs to the UPF0435 family
JOW61_04270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOW61_04275	COG4980	gas vesicle protein
JOW61_04280	COG1295	ribonuclease BN
JOW61_04285	COG0477	Major facilitator Superfamily
JOW61_04290	COG0387	Pfam Sodium calcium exchanger
JOW61_04300	COG0668	transmembrane transport
JOW61_04305	COG0535	radical SAM domain protein
JOW61_04315	COG0726	polysaccharide deacetylase
JOW61_04320	COG2084	Dehydrogenase
JOW61_04325	COG0598	Magnesium transport protein CorA
JOW61_04330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOW61_04335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOW61_04345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOW61_04350	COG4637	Psort location Cytoplasmic, score
JOW61_04360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JOW61_04365	COG0022	dehydrogenase e1 component
JOW61_04370	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOW61_04375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOW61_04380	COG3284	Transcriptional regulator
JOW61_04390	COG1742	UPF0060 membrane protein
JOW61_04415	COG4842	Belongs to the WXG100 family
JOW61_04420	COG1486	melibiose metabolic process
JOW61_04425	COG1737	Transcriptional regulator
JOW61_04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_04430	COG1263	PTS System
JOW61_04435	COG5434	Belongs to the glycosyl hydrolase 28 family
JOW61_04440	COG1132	(ABC) transporter
JOW61_04445	COG1132	(ABC) transporter
JOW61_04450	COG2259	Doxx family
JOW61_04455	COG2514	catechol 2,3-dioxygenase activity
JOW61_04460	COG4977	sequence-specific DNA binding
JOW61_04460	COG1917	Cupin 2, conserved barrel domain protein
JOW61_04465	COG2814	Major facilitator Superfamily
JOW61_04470	COG1082	Xylose isomerase domain protein TIM barrel
JOW61_04480	COG4585	Histidine kinase
JOW61_04485	COG2197	response regulator
JOW61_04490	COG1131	(ABC) transporter
JOW61_04495	COG1511	domain protein
JOW61_04495	COG0842	Transport permease protein
JOW61_04500	COG0842	Transport permease protein
JOW61_04505	COG1695	Transcriptional regulator
JOW61_04510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JOW61_04515	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JOW61_04520	COG1309	transcriptional regulator
JOW61_04525	COG2814	Major facilitator Superfamily
JOW61_04530	COG2318	DinB family
JOW61_04540	COG1846	Transcriptional regulator
JOW61_04545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOW61_04545	COG0392	lysyltransferase activity
JOW61_04550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JOW61_04555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_04560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_04565	COG0384	phenazine biosynthesis protein PhzF
JOW61_04570	COG0778	Nitroreductase
JOW61_04585	COG1090	epimerase
JOW61_04590	COG2137	regulation of response to DNA damage stimulus
JOW61_04600	COG2814	Major facilitator Superfamily
JOW61_04615	COG3103	Sh3 type 3 domain protein
JOW61_04620	COG5658	integral membrane protein
JOW61_04625	COG0596	Alpha beta hydrolase
JOW61_04630	COG0463	Glycosyl transferase, family 2
JOW61_04635	COG4485	Bacterial membrane protein, YfhO
JOW61_04640	COG1988	membrane-bound metal-dependent
JOW61_04645	COG1194	a g-specific adenine glycosylase
JOW61_04655	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_04670	COG3557	Belongs to the UPF0374 family
JOW61_04675	COG1132	(ABC) transporter
JOW61_04680	COG4129	membrane
JOW61_04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JOW61_04690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JOW61_04695	COG0735	belongs to the Fur family
JOW61_04805	COG4326	sporulation control protein
JOW61_04815	COG5577	PFAM Coat F domain
JOW61_04820	COG3340	Belongs to the peptidase S51 family
JOW61_04825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JOW61_04840	COG0753	catalase activity
JOW61_04845	COG1116	anion transmembrane transporter activity
JOW61_04850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JOW61_04855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JOW61_04860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOW61_04870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOW61_04880	COG1476	TRANSCRIPTIONal
JOW61_04890	COG3382	B3 4 domain protein
JOW61_04895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JOW61_04905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JOW61_04910	COG0789	Transcriptional regulator
JOW61_04915	COG1664	Polymer-forming cytoskeletal
JOW61_04920	COG1664	Polymer-forming cytoskeletal
JOW61_04925	COG2766	serine protein kinase
JOW61_04930	COG2718	Belongs to the UPF0229 family
JOW61_04935	COG1846	Transcriptional regulator
JOW61_04940	COG1566	PFAM secretion protein HlyD family protein
JOW61_04945	COG2814	Major facilitator Superfamily
JOW61_04950	COG0655	NAD(P)H dehydrogenase (quinone) activity
JOW61_04970	COG1725	Transcriptional regulator
JOW61_04975	COG1131	(ABC) transporter
JOW61_04980	COG1131	(ABC) transporter
JOW61_04985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JOW61_04990	COG1278	Cold shock
JOW61_04995	COG1464	Belongs to the NlpA lipoprotein family
JOW61_05000	COG3706	GGDEF domain
JOW61_05005	COG1823	symporter activity
JOW61_05010	COG5444	nuclease activity
JOW61_05035	COG0582	viral genome integration into host DNA
JOW61_05040	COG2946	Replication initiation factor
JOW61_05095	COG5644	endopeptidase inhibitor activity
JOW61_05100	COG0791	NLP P60 protein
JOW61_05100	COG0741	lytic transglycosylase activity
JOW61_05120	COG0457	Tetratricopeptide repeat
JOW61_05145	COG0737	Belongs to the 5'-nucleotidase family
JOW61_05145	COG1525	nuclease
JOW61_05145	COG4085	toxin activity
JOW61_05150	COG3764	Sortase (surface protein transpeptidase)
JOW61_05155	COG0564	pseudouridine synthase activity
JOW61_05165	COG0517	IMP dehydrogenase activity
JOW61_05170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JOW61_05175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JOW61_05175	COG3153	acetyltransferase
JOW61_05180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JOW61_05185	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JOW61_05190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JOW61_05195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JOW61_05200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JOW61_05205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOW61_05210	COG4585	Histidine kinase
JOW61_05210	COG2203	Gaf domain
JOW61_05215	COG2197	response regulator
JOW61_05220	COG0431	NADPH-dependent FMN reductase
JOW61_05235	COG1388	LysM domain
JOW61_05235	COG0791	NLP P60 protein
JOW61_05240	COG1959	2 iron, 2 sulfur cluster binding
JOW61_05245	COG0668	transmembrane transport
JOW61_05250	COG2719	SpoVR family
JOW61_05255	COG1785	Belongs to the alkaline phosphatase family
JOW61_05260	COG1388	LysM domain
JOW61_05260	COG0791	NLP P60 protein
JOW61_05265	COG0583	DNA-binding transcription factor activity
JOW61_05270	COG0372	Belongs to the citrate synthase family
JOW61_05275	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_05280	COG0531	amino acid
JOW61_05285	COG0733	neurotransmitter:sodium symporter activity
JOW61_05290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOW61_05295	COG0456	acetyltransferase
JOW61_05310	COG1595	DNA-templated transcription, initiation
JOW61_05315	COG0667	Aldo Keto reductase
JOW61_05320	COG0204	Acyl-transferase
JOW61_05325	COG1253	flavin adenine dinucleotide binding
JOW61_05330	COG0789	Transcriptional regulator
JOW61_05340	COG1253	flavin adenine dinucleotide binding
JOW61_05345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOW61_05350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOW61_05355	COG0584	glycerophosphoryl diester phosphodiesterase
JOW61_05365	COG0668	transmembrane transport
JOW61_05370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JOW61_05375	COG0726	polysaccharide deacetylase
JOW61_05380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JOW61_05385	COG1757	Na H antiporter
JOW61_05390	COG0589	response to stress
JOW61_05400	COG1132	(ABC) transporter
JOW61_05405	COG1132	(ABC) transporter
JOW61_05410	COG0702	epimerase
JOW61_05435	COG0189	ligase activity
JOW61_05440	COG0189	ligase activity
JOW61_05445	COG4399	Belongs to the UPF0754 family
JOW61_05450	COG3679	Belongs to the UPF0342 family
JOW61_05460	COG0561	phosphatase activity
JOW61_05465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JOW61_05470	COG0475	glutathione-regulated potassium exporter activity
JOW61_05475	COG0490	domain, Protein
JOW61_05485	COG1024	Enoyl-CoA hydratase
JOW61_05495	COG4152	abc transporter atp-binding protein
JOW61_05500	COG1668	transmembrane transport
JOW61_05505	COG0420	3'-5' exonuclease activity
JOW61_05510	COG4717	serine-type aminopeptidase activity
JOW61_05515	COG3481	metal-dependent phosphohydrolase, HD sub domain
JOW61_05525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JOW61_05555	COG1846	Transcriptional regulator
JOW61_05560	COG4980	gas vesicle protein
JOW61_05575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JOW61_05580	COG0537	adenosine 5'-monophosphoramidase activity
JOW61_05585	COG1131	(ABC) transporter
JOW61_05590	COG4473	ABC transporter
JOW61_05600	COG1473	amidohydrolase
JOW61_05605	COG3069	C4-dicarboxylate transmembrane transporter activity
JOW61_05615	COG2329	Antibiotic biosynthesis monooxygenase
JOW61_05620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JOW61_05625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JOW61_05630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JOW61_05635	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JOW61_05640	COG1309	transcriptional regulator
JOW61_05645	COG1511	domain protein
JOW61_05650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOW61_05655	COG4377	Putative membrane peptidase family (DUF2324)
JOW61_05665	COG1363	Peptidase, m42
JOW61_05670	COG4405	Protein conserved in bacteria
JOW61_05675	COG1301	dicarboxylic acid transport
JOW61_05685	COG1234	tRNA 3'-trailer cleavage
JOW61_05690	COG0095	Lipoate-protein ligase
JOW61_05695	COG0702	epimerase
JOW61_05700	COG0318	PFAM AMP-dependent synthetase and ligase
JOW61_05710	COG0501	Belongs to the peptidase M48B family
JOW61_05720	COG0456	acetyltransferase
JOW61_05725	COG0604	alcohol dehydrogenase
JOW61_05730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JOW61_05735	COG0406	alpha-ribazole phosphatase activity
JOW61_05740	COG0183	Belongs to the thiolase family
JOW61_05745	COG0318	PFAM AMP-dependent synthetase and ligase
JOW61_05750	COG1268	BioY protein
JOW61_05755	COG0840	transmembrane signaling receptor activity
JOW61_05765	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_05775	COG4903	ComK protein
JOW61_05780	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_05790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOW61_05805	COG0398	Pfam SNARE associated Golgi protein
JOW61_05810	COG0681	Belongs to the peptidase S26 family
JOW61_05815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JOW61_05820	COG1846	Transcriptional regulator
JOW61_05830	COG0738	Major facilitator superfamily
JOW61_05835	COG0673	inositol 2-dehydrogenase activity
JOW61_05840	COG0561	phosphatase activity
JOW61_05845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JOW61_05850	COG1609	Transcriptional regulator
JOW61_05855	COG3180	Ammonia monooxygenase
JOW61_05860	COG2814	Major facilitator Superfamily
JOW61_05860	COG0477	Major facilitator Superfamily
JOW61_05865	COG4533	DNA binding
JOW61_05880	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JOW61_05885	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JOW61_05890	COG1074	ATP-dependent DNA helicase activity
JOW61_05895	COG0420	3'-5' exonuclease activity
JOW61_05900	COG0419	ATPase involved in DNA repair
JOW61_05905	COG1403	HNH endonuclease
JOW61_05945	COG5337	Spore coat protein CotH
JOW61_05950	COG0179	Fumarylacetoacetate (FAA) hydrolase
JOW61_05960	COG1404	Belongs to the peptidase S8 family
JOW61_05970	COG0367	asparagine synthase
JOW61_05975	COG1562	ergosterol biosynthetic process
JOW61_05980	COG0534	Mate efflux family protein
JOW61_05985	COG1917	Cupin 2, conserved barrel domain protein
JOW61_05985	COG2207	Transcriptional regulator
JOW61_05990	COG1609	Transcriptional regulator
JOW61_05995	COG0673	inositol 2-dehydrogenase activity
JOW61_06000	COG2318	DinB family
JOW61_06005	COG1279	arginine transmembrane transporter activity
JOW61_06010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JOW61_06015	COG1357	PFAM Pentapeptide repeats (8 copies)
JOW61_06020	COG2267	carboxylic ester hydrolase activity
JOW61_06030	COG2153	protein acetylation
JOW61_06035	COG0646	methionine synthase
JOW61_06035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JOW61_06040	COG1666	GTP binding
JOW61_06045	COG2996	Protein conserved in bacteria
JOW61_06055	COG1307	EDD domain protein, DegV family
JOW61_06060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOW61_06080	COG0561	phosphatase activity
JOW61_06085	COG1073	alpha beta
JOW61_06090	COG2151	metal-sulfur cluster biosynthetic enzyme
JOW61_06110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JOW61_06115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JOW61_06125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JOW61_06130	COG0505	Belongs to the CarA family
JOW61_06135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JOW61_06140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOW61_06160	COG2267	carboxylic ester hydrolase activity
JOW61_06170	COG1744	ABC transporter substrate-binding protein PnrA-like
JOW61_06185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOW61_06190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JOW61_06195	COG5504	Zn-dependent protease
JOW61_06200	COG0444	Belongs to the ABC transporter superfamily
JOW61_06205	COG4608	Belongs to the ABC transporter superfamily
JOW61_06215	COG0601	transmembrane transport
JOW61_06220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOW61_06230	COG0180	Tryptophanyl-tRNA synthetase
JOW61_06235	COG4166	transmembrane transport
JOW61_06240	COG0601	transmembrane transport
JOW61_06245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOW61_06250	COG0444	Belongs to the ABC transporter superfamily
JOW61_06255	COG4608	Belongs to the ABC transporter superfamily
JOW61_06260	COG2814	Major facilitator Superfamily
JOW61_06265	COG0456	acetyltransferase
JOW61_06270	COG1393	Belongs to the ArsC family
JOW61_06275	COG0861	Integral membrane protein TerC family
JOW61_06285	COG4862	establishment of competence for transformation
JOW61_06295	COG4469	Competence protein
JOW61_06300	COG1164	Oligoendopeptidase f
JOW61_06310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JOW61_06315	COG2346	COG2346, Truncated hemoglobins
JOW61_06320	COG0741	lytic transglycosylase activity
JOW61_06325	COG4116	CYTH
JOW61_06335	COG2357	RelA SpoT domain protein
JOW61_06340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOW61_06345	COG0564	pseudouridine synthase activity
JOW61_06350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JOW61_06355	COG0569	domain protein
JOW61_06355	COG0475	glutathione-regulated potassium exporter activity
JOW61_06360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JOW61_06365	COG0352	thiamine-phosphate diphosphorylase activity
JOW61_06370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOW61_06375	COG2104	thiamine diphosphate biosynthetic process
JOW61_06380	COG2022	thiamine diphosphate biosynthetic process
JOW61_06385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JOW61_06390	COG0351	phosphomethylpyrimidine kinase
JOW61_06395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JOW61_06450	COG0210	DNA helicase
JOW61_06460	COG2153	protein acetylation
JOW61_06465	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JOW61_06470	COG2382	esterase
JOW61_06475	COG0626	cystathionine gamma-synthase activity
JOW61_06480	COG0626	cystathionine gamma-synthase activity
JOW61_06485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_06490	COG5505	Protein of unknown function (DUF819)
JOW61_06520	COG1396	sequence-specific DNA binding
JOW61_06595	COG0457	Tetratricopeptide repeat
JOW61_06600	COG5444	nuclease activity
JOW61_06610	COG3328	transposase activity
JOW61_06660	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JOW61_06670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_06670	COG3711	transcriptional antiterminator
JOW61_06675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOW61_06675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOW61_06675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_06680	COG1482	cell wall glycoprotein biosynthetic process
JOW61_06690	COG3328	transposase activity
JOW61_06695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_06705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOW61_06720	COG0109	protoheme IX farnesyltransferase activity
JOW61_06730	COG0726	polysaccharide deacetylase
JOW61_06745	COG5504	Zn-dependent protease
JOW61_06750	COG2205	protein histidine kinase activity
JOW61_06765	COG2427	Protein of unknown function (DUF1641)
JOW61_06775	COG1051	belongs to the nudix hydrolase family
JOW61_06785	COG2124	cytochrome p450
JOW61_06790	COG1819	glycosyl
JOW61_06800	COG1587	Uroporphyrinogen-III synthase
JOW61_06805	COG0390	transport system, permease component
JOW61_06810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JOW61_06815	COG0697	spore germination
JOW61_06830	COG1252	NADH dehydrogenase
JOW61_06835	COG1904	glucuronate isomerase
JOW61_06840	COG2211	Major facilitator Superfamily
JOW61_06845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JOW61_06850	COG1063	alcohol dehydrogenase
JOW61_06855	COG1312	Catalyzes the dehydration of D-mannonate
JOW61_06860	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_06865	COG2271	Major facilitator Superfamily
JOW61_06870	COG1609	Transcriptional regulator
JOW61_06875	COG0246	Mannitol dehydrogenase
JOW61_06880	COG2721	sulfolactate sulfo-lyase activity
JOW61_06885	COG0730	response to heat
JOW61_06890	COG2318	DinB family
JOW61_06910	COG0457	Tetratricopeptide repeat
JOW61_06925	COG5632	N-Acetylmuramoyl-L-alanine amidase
JOW61_06925	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_06925	COG1388	LysM domain
JOW61_06935	COG4195	phage-related replication protein
JOW61_06940	COG3546	catalase activity
JOW61_06945	COG2856	Zn peptidase
JOW61_06950	COG1396	sequence-specific DNA binding
JOW61_06960	COG1522	sequence-specific DNA binding
JOW61_06965	COG1484	DNA-dependent DNA replication
JOW61_06985	COG1595	DNA-templated transcription, initiation
JOW61_06990	COG3728	DNA packaging
JOW61_06990	COG5484	DNA packaging
JOW61_06995	COG1783	phage Terminase large subunit
JOW61_07000	COG5518	Phage portal protein
JOW61_07005	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JOW61_07010	COG4653	Phage capsid family
JOW61_07060	COG3953	SLT domain
JOW61_07060	COG5412	phage tail tape measure protein
JOW61_07060	COG3953	SLT domain
JOW61_07060	COG5412	phage tail tape measure protein
JOW61_07060	COG3953	SLT domain
JOW61_07060	COG5412	phage tail tape measure protein
JOW61_07065	COG1652	LysM domain
JOW61_07070	COG4193	domain, Protein
JOW61_07080	COG3628	GPW Gp25 family protein
JOW61_07085	COG3299	homolog of phage Mu protein gp47
JOW61_07090	COG3778	Protein conserved in bacteria
JOW61_07130	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_07130	COG5632	N-Acetylmuramoyl-L-alanine amidase
JOW61_07150	COG0306	phosphate transporter
JOW61_07155	COG1392	Phosphate transport regulator
JOW61_07160	COG0531	amino acid
JOW61_07165	COG0346	lactoylglutathione lyase activity
JOW61_07170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOW61_07175	COG0463	Glycosyl transferase, family 2
JOW61_07180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOW61_07185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOW61_07190	COG2362	D-Aminopeptidase
JOW61_07195	COG0601	transmembrane transport
JOW61_07200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOW61_07205	COG0444	Belongs to the ABC transporter superfamily
JOW61_07210	COG4166	transmembrane transport
JOW61_07215	COG1619	proteins homologs of microcin C7 resistance protein MccF
JOW61_07220	COG4948	Mandelate Racemase Muconate Lactonizing
JOW61_07225	COG0791	NLP P60 protein
JOW61_07230	COG4608	Belongs to the ABC transporter superfamily
JOW61_07235	COG2706	6-phosphogluconolactonase activity
JOW61_07245	COG1607	acyl-coa hydrolase
JOW61_07250	COG1017	nitric oxide dioxygenase activity
JOW61_07250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JOW61_07260	COG2323	membrane
JOW61_07265	COG2318	DinB family
JOW61_07270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_07275	COG2076	Multidrug Resistance protein
JOW61_07280	COG2076	Multidrug Resistance protein
JOW61_07285	COG0788	formyltetrahydrofolate deformylase activity
JOW61_07290	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOW61_07295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JOW61_07300	COG1764	response to oxidative stress
JOW61_07305	COG1846	Transcriptional regulator
JOW61_07310	COG1764	response to oxidative stress
JOW61_07320	COG0590	tRNA wobble adenosine to inosine editing
JOW61_07325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JOW61_07330	COG1404	Belongs to the peptidase S8 family
JOW61_07335	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_07340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOW61_07345	COG1122	ATPase activity
JOW61_07350	COG4721	ABC-type cobalt transport system, permease component
JOW61_07360	COG0745	RESPONSE REGULATOR receiver
JOW61_07365	COG5002	protein histidine kinase activity
JOW61_07365	COG3850	Histidine kinase
JOW61_07370	COG3212	peptidase
JOW61_07375	COG3212	peptidase
JOW61_07385	COG2239	Acts as a magnesium transporter
JOW61_07390	COG0789	Transcriptional regulator
JOW61_07405	COG1846	Transcriptional regulator
JOW61_07410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOW61_07415	COG0726	polysaccharide deacetylase
JOW61_07420	COG1408	metallophosphoesterase
JOW61_07430	COG0463	Glycosyl transferase, family 2
JOW61_07435	COG3285	dna ligase
JOW61_07435	COG1793	dna ligase
JOW61_07440	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JOW61_07445	COG3300	MHYT domain
JOW61_07445	COG5001	Diguanylate cyclase
JOW61_07450	COG0586	Pfam SNARE associated Golgi protein
JOW61_07455	COG0861	Integral membrane protein TerC family
JOW61_07460	COG1191	sigma factor activity
JOW61_07480	COG0501	Belongs to the peptidase M48B family
JOW61_07485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JOW61_07505	COG3594	Acyltransferase
JOW61_07510	COG5002	protein histidine kinase activity
JOW61_07515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOW61_07525	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JOW61_07530	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JOW61_07535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JOW61_07540	COG0436	Aminotransferase
JOW61_07545	COG1850	ribulose-bisphosphate carboxylase activity
JOW61_07550	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JOW61_07555	COG0235	Class ii aldolase
JOW61_07560	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JOW61_07565	COG3339	Conserved Protein
JOW61_07580	COG3852	Histidine kinase
JOW61_07585	COG1846	Transcriptional regulator
JOW61_07590	COG1360	Flagellar Motor Protein
JOW61_07595	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JOW61_07600	COG0542	response to heat
JOW61_07605	COG3949	Membrane
JOW61_07610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JOW61_07615	COG0720	synthase
JOW61_07620	COG0602	queuosine metabolic process
JOW61_07625	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JOW61_07635	COG4873	Protein conserved in bacteria
JOW61_07645	COG3773	Cell wall hydrolase
JOW61_07650	COG2244	polysaccharide biosynthetic process
JOW61_07655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_07660	COG2217	Heavy metal translocating P-type atpase
JOW61_07670	COG0006	proline dipeptidase activity
JOW61_07675	COG1609	Transcriptional regulator
JOW61_07680	COG3711	transcriptional antiterminator
JOW61_07685	COG2190	(PTS) system
JOW61_07685	COG1263	PTS System
JOW61_07685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_07690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_07695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOW61_07705	COG1533	DNA photolyase activity
JOW61_07710	COG0456	acetyltransferase
JOW61_07715	COG0840	transmembrane signaling receptor activity
JOW61_07720	COG2084	Dehydrogenase
JOW61_07725	COG3328	transposase activity
JOW61_07730	COG2340	Cysteine-rich secretory protein family
JOW61_07735	COG0768	penicillin binding
JOW61_07740	COG4191	Histidine kinase
JOW61_07745	COG0436	Aminotransferase
JOW61_07755	COG0835	chemotaxis
JOW61_07755	COG0784	Response regulator, receiver
JOW61_07765	COG2814	Major facilitator Superfamily
JOW61_07770	COG1376	ErfK ybiS ycfS ynhG family protein
JOW61_07775	COG1408	metallophosphoesterase
JOW61_07780	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_07785	COG2200	EAL domain
JOW61_07790	COG4703	Protein of unknown function (DUF1797)
JOW61_07795	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JOW61_07805	COG0517	IMP dehydrogenase activity
JOW61_07810	COG0583	DNA-binding transcription factor activity
JOW61_07815	COG0716	FMN binding
JOW61_07825	COG0716	FMN binding
JOW61_07830	COG2171	N-acyltransferase activity
JOW61_07835	COG1473	amidohydrolase
JOW61_07845	COG0668	transmembrane transport
JOW61_07850	COG0450	alkyl hydroperoxide reductase
JOW61_07855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_07875	COG0746	molybdenum cofactor guanylyltransferase activity
JOW61_07880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JOW61_07885	COG0303	'Molybdopterin
JOW61_07890	COG1763	Mo-molybdopterin cofactor biosynthetic process
JOW61_07895	COG0314	molybdopterin synthase activity
JOW61_07900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JOW61_07910	COG1132	(ABC) transporter
JOW61_07920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOW61_07925	COG1136	(ABC) transporter
JOW61_07930	COG0577	efflux transmembrane transporter activity
JOW61_07935	COG1349	DNA-binding transcription factor activity
JOW61_07940	COG1105	Belongs to the carbohydrate kinase PfkB family
JOW61_07945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_07945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOW61_07945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JOW61_07950	COG0681	Belongs to the peptidase S26 family
JOW61_07960	COG0488	(ABC) transporter
JOW61_07965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOW61_07970	COG2309	aminopeptidase activity
JOW61_07980	COG1077	Cell shape determining protein MreB Mrl
JOW61_07985	COG2002	toxin-antitoxin pair type II binding
JOW61_07990	COG3852	Histidine kinase
JOW61_07995	COG2105	PFAM AIG2 family protein
JOW61_07995	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JOW61_08000	COG0569	domain protein
JOW61_08005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JOW61_08010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOW61_08015	COG5503	Protein of unknown function (DUF1447)
JOW61_08020	COG0561	phosphatase activity
JOW61_08025	COG0242	peptide deformylase activity
JOW61_08040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JOW61_08045	COG0022	dehydrogenase e1 component
JOW61_08050	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOW61_08055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOW61_08060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_08070	COG1982	Orn Lys Arg decarboxylase major
JOW61_08075	COG4476	Belongs to the UPF0223 family
JOW61_08080	COG4493	Belongs to the UPF0637 family
JOW61_08090	COG0483	inositol monophosphate 1-phosphatase activity
JOW61_08105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JOW61_08145	COG1217	gtp-binding protein TYPA
JOW61_08155	COG4896	Protein conserved in bacteria
JOW61_08165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JOW61_08170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JOW61_08175	COG2066	Belongs to the glutaminase family
JOW61_08180	COG4838	Belongs to the UPF0358 family
JOW61_08185	COG0772	Belongs to the SEDS family
JOW61_08190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JOW61_08195	COG1612	heme a metabolic process
JOW61_08200	COG0109	protoheme IX farnesyltransferase activity
JOW61_08205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JOW61_08205	COG2010	Cytochrome c
JOW61_08210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOW61_08215	COG1845	cytochrome c oxidase, subunit III
JOW61_08220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JOW61_08225	COG3336	cytochrome c oxidase
JOW61_08235	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JOW61_08240	COG2340	Cysteine-rich secretory protein family
JOW61_08255	COG3679	Belongs to the UPF0342 family
JOW61_08260	COG4471	UPF0298 protein
JOW61_08265	COG0742	ribosomal rna small subunit methyltransferase
JOW61_08270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JOW61_08275	COG3314	Sporulation integral membrane protein YlbJ
JOW61_08280	COG1752	Esterase of the alpha-beta hydrolase superfamily
JOW61_08285	COG3480	Lon protease (S16) C-terminal proteolytic domain
JOW61_08290	COG1323	Belongs to the UPF0348 family
JOW61_08300	COG1399	metal-binding, possibly nucleic acid-binding protein
JOW61_08315	COG0454	-acetyltransferase
JOW61_08320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOW61_08325	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JOW61_08330	COG2001	Belongs to the MraZ family
JOW61_08335	COG0275	rRNA processing
JOW61_08340	COG4839	cell division protein FtsL
JOW61_08345	COG0768	penicillin binding
JOW61_08350	COG0768	penicillin binding
JOW61_08355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JOW61_08360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JOW61_08365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JOW61_08370	COG0772	Belongs to the SEDS family
JOW61_08375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOW61_08380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JOW61_08385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JOW61_08390	COG3879	Bacterial protein of unknown function (DUF881)
JOW61_08395	COG3879	Bacterial protein of unknown function (DUF881)
JOW61_08400	COG3856	small basic protein
JOW61_08405	COG0849	cell division
JOW61_08410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JOW61_08415	COG1404	Belongs to the peptidase S8 family
JOW61_08415	COG4412	M6 family metalloprotease domain protein
JOW61_08425	COG1191	sigma factor activity
JOW61_08430	COG1191	sigma factor activity
JOW61_08435	COG1119	ATPase activity
JOW61_08440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOW61_08445	COG1873	PFAM PRC-barrel domain
JOW61_08450	COG1496	oxidoreductase activity
JOW61_08455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JOW61_08460	COG1799	cell septum assembly
JOW61_08465	COG0762	integral membrane protein
JOW61_08470	COG2302	S4 RNA-binding domain
JOW61_08475	COG3599	regulation of cell shape
JOW61_08480	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JOW61_08485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JOW61_08490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JOW61_08495	COG0564	pseudouridine synthase activity
JOW61_08500	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JOW61_08505	COG2233	PERMEase
JOW61_08510	COG0540	Belongs to the ATCase OTCase family
JOW61_08515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JOW61_08520	COG0505	Belongs to the CarA family
JOW61_08525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JOW61_08530	COG0543	2 iron, 2 sulfur cluster binding
JOW61_08535	COG0167	dihydroorotate dehydrogenase activity
JOW61_08540	COG0284	orotidine-5'-phosphate decarboxylase activity
JOW61_08545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JOW61_08550	COG0175	sulfate reduction
JOW61_08555	COG0306	phosphate transporter
JOW61_08560	COG2046	Belongs to the sulfate adenylyltransferase family
JOW61_08565	COG0529	Catalyzes the synthesis of activated sulfate
JOW61_08570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JOW61_08575	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JOW61_08580	COG1648	precorrin-2 dehydrogenase activity
JOW61_08590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JOW61_08595	COG1561	YicC-like family, N-terminal region
JOW61_08605	COG0194	GDP metabolic process
JOW61_08610	COG1758	RNA polymerase activity
JOW61_08615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOW61_08620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOW61_08625	COG0242	peptide deformylase activity
JOW61_08630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JOW61_08635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOW61_08635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOW61_08640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JOW61_08645	COG0631	protein serine/threonine phosphatase activity
JOW61_08650	COG2815	serine threonine protein kinase
JOW61_08650	COG0515	serine threonine protein kinase
JOW61_08655	COG1162	GTPase activity
JOW61_08660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JOW61_08665	COG1564	THIamine pyrophosphokinase
JOW61_08675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JOW61_08680	COG1302	Protein conserved in bacteria
JOW61_08685	COG1461	Dihydroxyacetone kinase
JOW61_08690	COG1760	l-serine dehydratase
JOW61_08695	COG1760	l-serine dehydratase
JOW61_08700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOW61_08705	COG2050	protein possibly involved in aromatic compounds catabolism
JOW61_08705	COG1349	DNA-binding transcription factor activity
JOW61_08710	COG0416	fatty acid biosynthetic process
JOW61_08715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JOW61_08720	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_08730	COG0571	ribonuclease III activity
JOW61_08735	COG1196	nuclear chromosome segregation
JOW61_08740	COG0552	protein localization to endoplasmic reticulum
JOW61_08750	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JOW61_08755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOW61_08760	COG0228	four-way junction DNA binding
JOW61_08765	COG1837	Belongs to the UPF0109 family
JOW61_08775	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JOW61_08780	COG0336	Belongs to the RNA methyltransferase TrmD family
JOW61_08785	COG0335	large ribosomal subunit rRNA binding
JOW61_08790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JOW61_08795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOW61_08805	COG2257	FlhB HrpN YscU SpaS Family
JOW61_08810	COG0045	succinate-CoA ligase (ADP-forming) activity
JOW61_08815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JOW61_08820	COG0758	DNA mediated transformation
JOW61_08825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOW61_08830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JOW61_08835	COG4974	Belongs to the 'phage' integrase family
JOW61_08840	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JOW61_08845	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JOW61_08850	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JOW61_08855	COG1815	bacterial-type flagellum-dependent cell motility
JOW61_08860	COG1558	bacterial-type flagellum-dependent cell motility
JOW61_08865	COG1677	Flagellar hook-basal body complex protein FliE
JOW61_08875	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JOW61_08880	COG1317	bacterial-type flagellum organization
JOW61_08885	COG1157	protein secretion by the type III secretion system
JOW61_08890	COG2882	bacterial-type flagellum organization
JOW61_08895	COG3334	PFAM MgtE intracellular
JOW61_08900	COG3144	bacterial-type flagellum assembly
JOW61_08905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JOW61_08910	COG4786	Flagellar basal body rod
JOW61_08915	COG1582	Flagellar protein (FlbD)
JOW61_08920	COG1580	Controls the rotational direction of flagella during chemotaxis
JOW61_08925	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JOW61_08930	COG1776	CheC inhibitor of MCP methylation
JOW61_08930	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JOW61_08935	COG2201	protein-glutamate methylesterase activity
JOW61_08940	COG3190	flagellar
JOW61_08945	COG1338	Plays a role in the flagellum-specific transport system
JOW61_08950	COG1987	bacterial-type flagellum assembly
JOW61_08955	COG1684	flagellar biosynthetic protein fliR
JOW61_08960	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOW61_08965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOW61_08970	COG1419	protein localization to endoplasmic reticulum
JOW61_08975	COG0455	bacterial-type flagellum organization
JOW61_08980	COG2201	protein-glutamate methylesterase activity
JOW61_08985	COG0643	Histidine kinase
JOW61_08985	COG2198	Histidine kinase
JOW61_08990	COG0835	chemotaxis
JOW61_09000	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JOW61_09005	COG1191	sigma factor activity
JOW61_09015	COG0052	Belongs to the universal ribosomal protein uS2 family
JOW61_09020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JOW61_09025	COG0528	UMP kinase activity
JOW61_09030	COG0233	cytoplasmic translational termination
JOW61_09035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOW61_09040	COG4589	Belongs to the CDS family
JOW61_09045	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JOW61_09050	COG0750	zinc metalloprotease
JOW61_09055	COG0442	prolyl-tRNA aminoacylation
JOW61_09060	COG2176	DNA-directed DNA polymerase activity
JOW61_09065	COG0779	Required for maturation of 30S ribosomal subunits
JOW61_09070	COG0195	Participates in both transcription termination and antitermination
JOW61_09075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JOW61_09080	COG1358	cellular component organization or biogenesis
JOW61_09085	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JOW61_09090	COG1550	Protein conserved in bacteria
JOW61_09095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JOW61_09100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JOW61_09105	COG0196	riboflavin kinase activity
JOW61_09110	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JOW61_09115	COG1185	polyribonucleotide nucleotidyltransferase activity
JOW61_09120	COG0726	polysaccharide deacetylase
JOW61_09125	COG0612	Peptidase, M16
JOW61_09130	COG1873	PFAM PRC-barrel domain
JOW61_09135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOW61_09140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOW61_09145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JOW61_09150	COG0527	aspartate kinase activity
JOW61_09155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOW61_09160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOW61_09165	COG0740	serine-type endopeptidase activity
JOW61_09175	COG1674	ftsk spoiiie
JOW61_09175	COG4980	gas vesicle protein
JOW61_09180	COG2188	Transcriptional regulator
JOW61_09185	COG2814	Major facilitator Superfamily
JOW61_09190	COG0612	Peptidase, M16
JOW61_09195	COG0612	Peptidase, M16
JOW61_09200	COG0300	oxidoreductase activity
JOW61_09215	COG1426	Protein conserved in bacteria
JOW61_09220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOW61_09225	COG1058	Belongs to the CinA family
JOW61_09225	COG1546	Belongs to the CinA family
JOW61_09230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JOW61_09235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JOW61_09240	COG1418	mRNA catabolic process
JOW61_09245	COG1692	metallophosphoesterase
JOW61_09250	COG2359	stage V sporulation protein S
JOW61_09255	COG1063	alcohol dehydrogenase
JOW61_09260	COG0156	8-amino-7-oxononanoate synthase activity
JOW61_09265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JOW61_09270	COG4550	Control of competence regulator ComK, YlbF/YmcA
JOW61_09280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOW61_09285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JOW61_09375	COG3328	transposase activity
JOW61_09390	COG3226	Transcriptional regulator
JOW61_09400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOW61_09405	COG1404	Belongs to the peptidase S8 family
JOW61_09415	COG4195	phage-related replication protein
JOW61_09420	COG1764	response to oxidative stress
JOW61_09425	COG2076	Multidrug Resistance protein
JOW61_09430	COG2076	Multidrug Resistance protein
JOW61_09445	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JOW61_09450	COG1923	regulation of RNA biosynthetic process
JOW61_09465	COG1780	Probably involved in ribonucleotide reductase function
JOW61_09470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOW61_09475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOW61_09480	COG4112	unkown
JOW61_09485	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOW61_09490	COG0464	growth
JOW61_09495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOW61_09500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JOW61_09505	COG0789	Transcriptional regulator
JOW61_09510	COG0174	glutamine synthetase
JOW61_09515	COG4974	Belongs to the 'phage' integrase family
JOW61_09535	COG3645	SOS response
JOW61_09535	COG3646	Phage regulatory protein
JOW61_09680	COG5412	phage tail tape measure protein
JOW61_09680	COG3953	SLT domain
JOW61_09725	COG5632	N-Acetylmuramoyl-L-alanine amidase
JOW61_09725	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_09725	COG1388	LysM domain
JOW61_09735	COG5444	nuclease activity
JOW61_09770	COG4282	regulation of fungal-type cell wall biogenesis
JOW61_09805	COG3655	Transcriptional regulator
JOW61_09830	COG0135	phosphoribosylanthranilate isomerase activity
JOW61_09835	COG2211	Major facilitator Superfamily
JOW61_09850	COG3507	Belongs to the glycosyl hydrolase 43 family
JOW61_09855	COG1940	carbohydrate kinase activity
JOW61_09860	COG2115	Belongs to the xylose isomerase family
JOW61_09865	COG1070	Carbohydrate kinase
JOW61_09875	COG3328	transposase activity
JOW61_09880	COG1525	nuclease
JOW61_09885	COG2814	Major facilitator Superfamily
JOW61_09890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOW61_09905	COG0756	dUTP diphosphatase activity
JOW61_09945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOW61_09960	COG3832	glyoxalase III activity
JOW61_10000	COG4195	phage-related replication protein
JOW61_10010	COG0346	lactoylglutathione lyase activity
JOW61_10015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOW61_10020	COG1388	LysM domain
JOW61_10025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JOW61_10030	COG4224	UPF0291 protein
JOW61_10035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JOW61_10045	COG3763	UPF0154 protein
JOW61_10055	COG0785	Cytochrome C biogenesis protein
JOW61_10060	COG2201	protein-glutamate methylesterase activity
JOW61_10065	COG4846	Membrane protein involved in cytochrome C biogenesis
JOW61_10075	COG0071	Belongs to the small heat shock protein (HSP20) family
JOW61_10090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JOW61_10095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_10115	COG0824	Thioesterase
JOW61_10125	COG4841	protein insertion into membrane
JOW61_10130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JOW61_10135	COG1832	CoA-binding protein
JOW61_10140	COG0187	DNA topoisomerase II activity
JOW61_10145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOW61_10155	COG1115	amino acid carrier protein
JOW61_10160	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JOW61_10170	COG5520	Belongs to the glycosyl hydrolase 30 family
JOW61_10180	COG2246	polysaccharide biosynthetic process
JOW61_10185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JOW61_10190	COG0586	Pfam SNARE associated Golgi protein
JOW61_10195	COG2404	hydrolase activity, acting on ester bonds
JOW61_10200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JOW61_10205	COG1024	Enoyl-CoA hydratase
JOW61_10210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JOW61_10215	COG0511	ligase activity, forming carbon-carbon bonds
JOW61_10220	COG0439	Biotin carboxylase
JOW61_10225	COG0318	PFAM AMP-dependent synthetase and ligase
JOW61_10230	COG1960	acyl-CoA dehydrogenase activity
JOW61_10240	COG1649	PFAM Uncharacterised BCR, COG1649
JOW61_10255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JOW61_10260	COG2027	D-alanyl-D-alanine carboxypeptidase
JOW61_10265	COG2017	converts alpha-aldose to the beta-anomer
JOW61_10270	COG0534	Mate efflux family protein
JOW61_10290	COG0582	viral genome integration into host DNA
JOW61_10295	COG0166	Belongs to the GPI family
JOW61_10300	COG0405	Gamma-glutamyltransferase
JOW61_10305	COG0583	DNA-binding transcription factor activity
JOW61_10310	COG0604	alcohol dehydrogenase
JOW61_10315	COG0493	'glutamate synthase
JOW61_10320	COG0067	glutamate synthase
JOW61_10320	COG0069	glutamate synthase activity
JOW61_10320	COG0070	glutamate synthase
JOW61_10325	COG0583	DNA-binding transcription factor activity
JOW61_10355	COG0300	oxidoreductase activity
JOW61_10360	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOW61_10370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_10385	COG1131	(ABC) transporter
JOW61_10395	COG2814	Major facilitator Superfamily
JOW61_10400	COG3328	transposase activity
JOW61_10430	COG3328	transposase activity
JOW61_10485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JOW61_10490	COG2226	methyltransferase
JOW61_10495	COG2211	Major facilitator Superfamily
JOW61_10500	COG3328	transposase activity
JOW61_10530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOW61_10550	COG5444	nuclease activity
JOW61_10555	COG4282	regulation of fungal-type cell wall biogenesis
JOW61_10560	COG1231	oxidoreductase activity
JOW61_10565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOW61_10570	COG0662	Cupin 2, conserved barrel domain protein
JOW61_10570	COG2207	Transcriptional regulator
JOW61_10575	COG0456	acetyltransferase
JOW61_10580	COG1309	transcriptional regulator
JOW61_10585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOW61_10590	COG3708	Transcriptional regulator
JOW61_10595	COG2378	regulation of single-species biofilm formation
JOW61_10605	COG0640	Transcriptional regulator
JOW61_10610	COG0741	lytic transglycosylase activity
JOW61_10615	COG2322	membrane
JOW61_10630	COG1619	proteins homologs of microcin C7 resistance protein MccF
JOW61_10635	COG3239	Fatty acid desaturase
JOW61_10640	COG4585	Histidine kinase
JOW61_10645	COG2197	response regulator
JOW61_10650	COG3584	3D domain protein
JOW61_10650	COG1388	LysM domain
JOW61_10655	COG0514	ATP-dependent DNA helicase (RecQ)
JOW61_10665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOW61_10670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JOW61_10685	COG0071	Belongs to the small heat shock protein (HSP20) family
JOW61_10710	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_10715	COG1657	PFAM Prenyltransferase squalene oxidase
JOW61_10720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOW61_10725	COG0733	neurotransmitter:sodium symporter activity
JOW61_10730	COG0385	Bile acid
JOW61_10735	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOW61_10740	COG0567	Dehydrogenase, E1 component
JOW61_10745	COG4548	von Willebrand factor, type A
JOW61_10750	COG0714	Associated with various cellular activities
JOW61_10755	COG2032	superoxide dismutase activity
JOW61_10760	COG0791	NLP P60 protein
JOW61_10760	COG1388	LysM domain
JOW61_10765	COG1819	glycosyl
JOW61_10770	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOW61_10775	COG0534	Mate efflux family protein
JOW61_10780	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_10785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JOW61_10790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JOW61_10800	COG2962	Rard protein
JOW61_10820	COG1942	4-Oxalocrotonate Tautomerase
JOW61_10825	COG1733	regulation of RNA biosynthetic process
JOW61_10830	COG0778	Nitroreductase
JOW61_10840	COG0400	carboxylic ester hydrolase activity
JOW61_10855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOW61_10860	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_10860	COG0793	Belongs to the peptidase S41A family
JOW61_10865	COG2226	methyltransferase
JOW61_10875	COG1876	peptidase activity
JOW61_10880	COG0813	purine-nucleoside phosphorylase activity
JOW61_10895	COG0671	phosphoesterase, PA-phosphatase related
JOW61_10915	COG4479	Belongs to the UPF0346 family
JOW61_10925	COG1509	lysine 2,3-aminomutase activity
JOW61_10930	COG0456	acetyltransferase
JOW61_10935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOW61_10940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JOW61_10945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOW61_10950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JOW61_10965	COG0456	acetyltransferase
JOW61_10970	COG0463	Glycosyl transferase, family 2
JOW61_10985	COG4641	Protein conserved in bacteria
JOW61_10990	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JOW61_10995	COG1086	Polysaccharide biosynthesis protein
JOW61_11000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOW61_11005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOW61_11010	COG1846	Transcriptional regulator
JOW61_11015	COG0534	Mate efflux family protein
JOW61_11025	COG4698	Protein conserved in bacteria
JOW61_11030	COG2755	lipolytic protein G-D-S-L family
JOW61_11035	COG1999	signal sequence binding
JOW61_11045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JOW61_11050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JOW61_11055	COG1272	protein, Hemolysin III
JOW61_11060	COG0204	Acyl-transferase
JOW61_11065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOW61_11070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JOW61_11080	COG2521	methyltransferase
JOW61_11080	COG2136	Putative SAM-dependent methyltransferase
JOW61_11090	COG0129	dihydroxy-acid dehydratase activity
JOW61_11095	COG1413	lyase activity
JOW61_11100	COG1418	mRNA catabolic process
JOW61_11105	COG0386	Belongs to the glutathione peroxidase family
JOW61_11110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JOW61_11115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOW61_11125	COG1278	Cold shock
JOW61_11145	COG0328	RNA-DNA hybrid ribonuclease activity
JOW61_11150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOW61_11155	COG0328	RNA-DNA hybrid ribonuclease activity
JOW61_11165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOW61_11180	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JOW61_11190	COG1755	Isoprenylcysteine carboxyl methyltransferase
JOW61_11195	COG3424	synthase
JOW61_11200	COG2233	PERMEase
JOW61_11205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOW61_11210	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JOW61_11220	COG0800	Aldolase
JOW61_11225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOW61_11230	COG1609	Transcriptional regulator
JOW61_11235	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JOW61_11240	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_11245	COG1199	ATP-dependent helicase activity
JOW61_11260	COG0116	Belongs to the methyltransferase superfamily
JOW61_11275	COG4474	Belongs to the UPF0398 family
JOW61_11290	COG3359	exonuclease
JOW61_11295	COG1205	dead DEAH box helicase
JOW61_11295	COG1111	helicase
JOW61_11300	COG2190	(PTS) system
JOW61_11305	COG0071	Belongs to the small heat shock protein (HSP20) family
JOW61_11340	COG3331	DNA recombination
JOW61_11345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JOW61_11345	COG4499	WXG100 protein secretion system (Wss), protein YukC
JOW61_11355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOW61_11360	COG3935	DnaD domain protein
JOW61_11365	COG0017	Asparaginyl-tRNA synthetase
JOW61_11370	COG0436	Aminotransferase
JOW61_11375	COG5353	protein conserved in bacteria
JOW61_11385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JOW61_11385	COG1199	ATP-dependent helicase activity
JOW61_11390	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JOW61_11395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JOW61_11400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JOW61_11405	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JOW61_11405	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JOW61_11410	COG0617	tRNA 3'-terminal CCA addition
JOW61_11415	COG0438	transferase activity, transferring glycosyl groups
JOW61_11420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JOW61_11425	COG1803	Methylglyoxal synthase
JOW61_11430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JOW61_11435	COG1694	Mazg nucleotide pyrophosphohydrolase
JOW61_11440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOW61_11450	COG4347	Protein of unknown function (DUF1405)
JOW61_11455	COG2010	Cytochrome c
JOW61_11455	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JOW61_11460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JOW61_11465	COG0723	plastoquinol--plastocyanin reductase activity
JOW61_11475	COG5582	Belongs to the UPF0302 family
JOW61_11480	COG0457	Tetratricopeptide repeat
JOW61_11485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JOW61_11490	COG0287	Prephenate dehydrogenase
JOW61_11505	COG0133	tryptophan synthase activity
JOW61_11510	COG0135	phosphoribosylanthranilate isomerase activity
JOW61_11520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JOW61_11525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOW61_11530	COG4401	Chorismate mutase type I
JOW61_11535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JOW61_11540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JOW61_11545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JOW61_11550	COG0105	UTP biosynthetic process
JOW61_11555	COG0142	geranyltranstransferase activity
JOW61_11560	COG2226	methyltransferase
JOW61_11565	COG0142	geranyltranstransferase activity
JOW61_11575	COG0302	gtp cyclohydrolase
JOW61_11580	COG0776	regulation of translation
JOW61_11585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JOW61_11600	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JOW61_11605	COG1160	GTP binding
JOW61_11630	COG1304	FMN binding
JOW61_11635	COG0539	negative regulation of cytoplasmic translation
JOW61_11640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JOW61_11650	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JOW61_11655	COG2959	enzyme of heme biosynthesis
JOW61_11660	COG3773	Cell wall hydrolase
JOW61_11660	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_11665	COG2339	peptidase activity
JOW61_11670	COG0492	ferredoxin-NADP+ reductase activity
JOW61_11675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JOW61_11680	COG4862	establishment of competence for transformation
JOW61_11685	COG1408	metallophosphoesterase
JOW61_11695	COG1388	LysM domain
JOW61_11700	COG1266	CAAX protease self-immunity
JOW61_11705	COG0514	ATP-dependent DNA helicase (RecQ)
JOW61_11710	COG4955	Helix-turn-helix domain
JOW61_11715	COG1141	Ferredoxin
JOW61_11720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JOW61_11725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JOW61_11730	COG0710	3-dehydroquinate dehydratase activity
JOW61_11740	COG1595	DNA-templated transcription, initiation
JOW61_11745	COG5002	protein histidine kinase activity
JOW61_11750	COG0745	RESPONSE REGULATOR receiver
JOW61_11755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JOW61_11760	COG1333	cytochrome c biogenesis protein
JOW61_11765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_11770	COG1187	pseudouridine synthase activity
JOW61_11775	COG0700	Nucleoside recognition
JOW61_11780	COG2715	membrane protein required for spore maturation
JOW61_11785	COG1686	Belongs to the peptidase S11 family
JOW61_11795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOW61_11800	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOW61_11805	COG1547	Domain of unknown function (DUF309)
JOW61_11810	COG0456	acetyltransferase
JOW61_11815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JOW61_11820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JOW61_11820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JOW61_11825	COG0307	riboflavin synthase, alpha
JOW61_11830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOW61_11830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOW61_11840	COG0681	Belongs to the peptidase S26 family
JOW61_11850	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
JOW61_11900	COG3328	transposase activity
JOW61_11950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOW61_11960	COG4086	secreted protein
JOW61_11965	COG0019	diaminopimelate decarboxylase activity
JOW61_11970	COG0697	spore germination
JOW61_11985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOW61_12005	COG1191	sigma factor activity
JOW61_12010	COG2172	sigma factor antagonist activity
JOW61_12015	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_12020	COG1686	Belongs to the peptidase S11 family
JOW61_12025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JOW61_12030	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JOW61_12035	COG4974	Belongs to the 'phage' integrase family
JOW61_12045	COG0735	belongs to the Fur family
JOW61_12050	COG1300	Membrane
JOW61_12060	COG0281	malic enzyme
JOW61_12065	COG1757	Na H antiporter
JOW61_12070	COG1027	Aspartate ammonia-lyase
JOW61_12075	COG0252	asparaginase activity
JOW61_12080	COG1396	sequence-specific DNA binding
JOW61_12085	COG1379	DNA repair
JOW61_12090	COG0494	nUDIX hydrolase
JOW61_12100	COG0667	Aldo Keto reductase
JOW61_12110	COG1073	alpha beta
JOW61_12120	COG4918	Iron-sulphur cluster biosynthesis
JOW61_12125	COG0456	acetyltransferase
JOW61_12125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JOW61_12130	COG2329	Antibiotic biosynthesis monooxygenase
JOW61_12135	COG0456	acetyltransferase
JOW61_12145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOW61_12155	COG2211	Major facilitator Superfamily
JOW61_12165	COG0346	lactoylglutathione lyase activity
JOW61_12170	COG1072	(Pantothenic acid kinase))
JOW61_12175	COG3048	D-serine ammonia-lyase activity
JOW61_12180	COG0300	oxidoreductase activity
JOW61_12185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOW61_12190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOW61_12195	COG4187	Peptidase family M20/M25/M40
JOW61_12200	COG1902	pentaerythritol trinitrate reductase activity
JOW61_12210	COG0596	Alpha beta hydrolase
JOW61_12220	COG1234	tRNA 3'-trailer cleavage
JOW61_12225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOW61_12230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOW61_12235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOW61_12245	COG0706	membrane insertase activity
JOW61_12250	COG3361	conserved protein (COG2071)
JOW61_12255	COG2195	Cleaves the N-terminal amino acid of tripeptides
JOW61_12265	COG0346	lactoylglutathione lyase activity
JOW61_12275	COG1376	ErfK ybiS ycfS ynhG family protein
JOW61_12280	COG4129	membrane
JOW61_12285	COG1126	abc transporter atp-binding protein
JOW61_12290	COG0765	amino acid transport
JOW61_12295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JOW61_12305	COG1597	lipid kinase activity
JOW61_12315	COG0789	Transcriptional regulator
JOW61_12315	COG4978	Transcriptional regulator
JOW61_12320	COG0508	dehydrogenase complex catalyzes the overall conversion of
JOW61_12325	COG0022	dehydrogenase e1 component
JOW61_12330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JOW61_12335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JOW61_12340	COG3426	butyrate kinase activity
JOW61_12345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JOW61_12350	COG0280	phosphate acetyltransferase
JOW61_12355	COG3290	protein histidine kinase activity
JOW61_12355	COG3829	transcription factor binding
JOW61_12365	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JOW61_12370	COG2079	MmgE PrpD family protein
JOW61_12375	COG0372	Belongs to the citrate synthase family
JOW61_12380	COG1960	acyl-CoA dehydrogenase activity
JOW61_12385	COG1250	3-hydroxyacyl-CoA dehydrogenase
JOW61_12390	COG0183	Belongs to the thiolase family
JOW61_12395	COG0584	glycerophosphoryl diester phosphodiesterase
JOW61_12400	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOW61_12415	COG1902	pentaerythritol trinitrate reductase activity
JOW61_12420	COG0745	RESPONSE REGULATOR receiver
JOW61_12425	COG0750	zinc metalloprotease
JOW61_12430	COG0497	DNA recombination
JOW61_12435	COG1438	arginine binding
JOW61_12440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JOW61_12445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JOW61_12450	COG0142	geranyltranstransferase activity
JOW61_12455	COG1722	exodeoxyribonuclease VII activity
JOW61_12460	COG1570	exodeoxyribonuclease VII activity
JOW61_12465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JOW61_12470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOW61_12475	COG1302	Protein conserved in bacteria
JOW61_12480	COG0439	Biotin carboxylase
JOW61_12485	COG0511	ligase activity, forming carbon-carbon bonds
JOW61_12530	COG3854	ATPases associated with a variety of cellular activities
JOW61_12540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JOW61_12545	COG0006	proline dipeptidase activity
JOW61_12550	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JOW61_12560	COG3872	metal-dependent enzyme
JOW61_12570	COG1752	Esterase of the alpha-beta hydrolase superfamily
JOW61_12575	COG1321	iron dependent repressor
JOW61_12580	COG0095	Lipoate-protein ligase
JOW61_12585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOW61_12590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOW61_12595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOW61_12600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JOW61_12605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JOW61_12620	COG1396	sequence-specific DNA binding
JOW61_12630	COG0681	Belongs to the peptidase S26 family
JOW61_12655	COG4940	Competence protein ComGF
JOW61_12665	COG4970	Tfp pilus assembly protein FimT
JOW61_12670	COG4537	Required for transformation and DNA binding
JOW61_12675	COG1459	type II secretion system
JOW61_12680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOW61_12685	COG0517	IMP dehydrogenase activity
JOW61_12690	COG0598	Magnesium transport protein CorA
JOW61_12695	COG1253	flavin adenine dinucleotide binding
JOW61_12700	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_12710	COG1393	Belongs to the ArsC family
JOW61_12720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOW61_12730	COG0011	TIGRFAM Protein of
JOW61_12740	COG2866	Carboxypeptidase
JOW61_12745	COG1368	sulfuric ester hydrolase activity
JOW61_12750	COG1940	carbohydrate kinase activity
JOW61_12755	COG4483	Protein conserved in bacteria
JOW61_12760	COG0457	Tetratricopeptide repeat
JOW61_12760	COG0705	Rhomboid family
JOW61_12770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOW61_12780	COG0438	transferase activity, transferring glycosyl groups
JOW61_12795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOW61_12800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JOW61_12805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JOW61_12810	COG0581	inorganic phosphate transmembrane transporter activity
JOW61_12815	COG0573	inorganic phosphate transmembrane transporter activity
JOW61_12820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JOW61_12825	COG0768	penicillin binding
JOW61_12830	COG0477	Major facilitator Superfamily
JOW61_12835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOW61_12840	COG2839	Protein conserved in bacteria
JOW61_12845	COG5521	maltodextrose utilization protein MalA
JOW61_12850	COG1388	LysM domain
JOW61_12855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JOW61_12860	COG4709	membrane
JOW61_12865	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JOW61_12870	COG0735	belongs to the Fur family
JOW61_12875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOW61_12885	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JOW61_12890	COG0513	Belongs to the DEAD box helicase family
JOW61_12900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JOW61_12905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JOW61_12910	COG2384	SAM-dependent methyltransferase
JOW61_12915	COG2010	Cytochrome c
JOW61_12920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOW61_12925	COG0358	DNA primase activity
JOW61_12930	COG1671	Belongs to the UPF0178 family
JOW61_12935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JOW61_12940	COG0517	IMP dehydrogenase activity
JOW61_12945	COG0751	glycine-tRNA ligase activity
JOW61_12950	COG0752	glycyl-tRNA synthetase alpha subunit
JOW61_12955	COG1381	Involved in DNA repair and RecF pathway recombination
JOW61_12965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JOW61_12970	COG0295	cytidine deaminase activity
JOW61_12975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JOW61_12980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JOW61_12985	COG1480	7TM receptor with intracellular HD hydrolase
JOW61_12990	COG1702	phosphate starvation-inducible protein PhoH
JOW61_12995	COG0561	phosphatase activity
JOW61_13010	COG4864	UPF0365 protein
JOW61_13015	COG1030	water channel activity
JOW61_13020	COG1610	YqeY-like protein
JOW61_13030	COG1283	sodium-dependent phosphate transmembrane transporter activity
JOW61_13035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JOW61_13040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JOW61_13045	COG2264	protein methyltransferase activity
JOW61_13050	COG0484	heat shock protein binding
JOW61_13055	COG0443	Heat shock 70 kDa protein
JOW61_13060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOW61_13065	COG1420	regulation of RNA biosynthetic process
JOW61_13070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JOW61_13075	COG0481	GTPase activity
JOW61_13085	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOW61_13090	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JOW61_13095	COG0268	Binds directly to 16S ribosomal RNA
JOW61_13100	COG1466	dna polymerase III delta subunit
JOW61_13115	COG2333	competence protein COMEC
JOW61_13115	COG0658	competence protein
JOW61_13120	COG2131	deaminase
JOW61_13125	COG1596	polysaccharide export
JOW61_13125	COG1555	photosystem II stabilization
JOW61_13130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOW61_13135	COG2226	methyltransferase
JOW61_13140	COG0799	negative regulation of ribosome biogenesis
JOW61_13145	COG1713	HD superfamily hydrolase involved in NAD metabolism
JOW61_13150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOW61_13155	COG1534	Rna-binding protein
JOW61_13160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JOW61_13165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JOW61_13170	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JOW61_13180	COG2755	lipolytic protein G-D-S-L family
JOW61_13185	COG5632	N-Acetylmuramoyl-L-alanine amidase
JOW61_13185	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_13190	COG0398	Pfam SNARE associated Golgi protein
JOW61_13195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JOW61_13205	COG3209	COG3209 Rhs family protein
JOW61_13225	COG0114	fumarate hydratase activity
JOW61_13230	COG0583	DNA-binding transcription factor activity
JOW61_13240	COG0457	Tetratricopeptide repeat
JOW61_13365	COG4978	Transcriptional regulator
JOW61_13365	COG0789	Transcriptional regulator
JOW61_13370	COG2814	Major facilitator Superfamily
JOW61_13375	COG0456	acetyltransferase
JOW61_13380	COG1253	flavin adenine dinucleotide binding
JOW61_13390	COG0697	spore germination
JOW61_13395	COG0583	DNA-binding transcription factor activity
JOW61_13400	COG2072	flavoprotein involved in K transport
JOW61_13405	COG1230	cation diffusion facilitator family transporter
JOW61_13415	COG1114	Component of the transport system for branched-chain amino acids
JOW61_13420	COG1687	branched-chain amino acid
JOW61_13430	COG1522	sequence-specific DNA binding
JOW61_13435	COG2732	(Barnase) inhibitor
JOW61_13440	COG2124	cytochrome p450
JOW61_13455	COG1335	isochorismatase
JOW61_13475	COG2318	DinB family
JOW61_13485	COG2070	2-Nitropropane dioxygenase
JOW61_13490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JOW61_13510	COG3443	Belongs to the bacterial solute-binding protein 9 family
JOW61_13515	COG1595	DNA-templated transcription, initiation
JOW61_13520	COG0667	Aldo Keto reductase
JOW61_13525	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_13530	COG5566	PFAM Mor transcription activator
JOW61_13540	COG4991	sh3 domain protein
JOW61_13545	COG4991	sh3 domain protein
JOW61_13555	COG0346	lactoylglutathione lyase activity
JOW61_13565	COG5577	PFAM Coat F domain
JOW61_13570	COG1063	alcohol dehydrogenase
JOW61_13580	COG5577	PFAM Coat F domain
JOW61_13585	COG0789	Transcriptional regulator
JOW61_13595	COG1064	alcohol dehydrogenase
JOW61_13600	COG0693	protein deglycase activity
JOW61_13605	COG1621	beta-fructofuranosidase activity
JOW61_13610	COG3716	PTS system mannose fructose sorbose family IID component
JOW61_13615	COG3715	PTS system
JOW61_13620	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_13625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_13630	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JOW61_13630	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JOW61_13640	COG1113	amino acid transport
JOW61_13645	COG1280	lysine exporter protein (LysE YggA)
JOW61_13650	COG1378	Sugar-specific transcriptional regulator TrmB
JOW61_13655	COG1595	DNA-templated transcription, initiation
JOW61_13680	COG1309	transcriptional regulator
JOW61_13685	COG2226	methyltransferase
JOW61_13700	COG2116	formate transmembrane transporter activity
JOW61_13705	COG5609	conserved protein (DUF2294)
JOW61_13710	COG3383	formate dehydrogenase (NAD+) activity
JOW61_13715	COG2427	Protein of unknown function (DUF1641)
JOW61_13730	COG0626	cystathionine gamma-synthase activity
JOW61_13735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JOW61_13740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JOW61_13745	COG2226	methyltransferase
JOW61_13760	COG0768	penicillin binding
JOW61_13765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JOW61_13770	COG0572	uridine kinase
JOW61_13775	COG0826	peptidase U32
JOW61_13780	COG0826	peptidase U32
JOW61_13785	COG4122	O-methyltransferase activity
JOW61_13790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOW61_13795	COG3906	Belongs to the UPF0473 family
JOW61_13800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JOW61_13805	COG4472	Bacterial protein of unknown function (DUF965)
JOW61_13810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JOW61_13815	COG0628	permease
JOW61_13820	COG1126	abc transporter atp-binding protein
JOW61_13825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JOW61_13830	COG0765	amino acid transport
JOW61_13835	COG0765	amino acid transport
JOW61_13850	COG3881	PFAM PRC-barrel domain
JOW61_13855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JOW61_13860	COG0457	Tetratricopeptide repeat
JOW61_13865	COG0482	sulfurtransferase activity
JOW61_13870	COG1104	cysteine desulfurase activity
JOW61_13875	COG1959	2 iron, 2 sulfur cluster binding
JOW61_13880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JOW61_13885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JOW61_13895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JOW61_13900	COG0124	histidyl-tRNA synthetase
JOW61_13910	COG4991	sh3 domain protein
JOW61_13910	COG3103	Sh3 type 3 domain protein
JOW61_13910	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOW61_13915	COG1490	D-aminoacyl-tRNA deacylase activity
JOW61_13920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOW61_13925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOW61_13930	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JOW61_13930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JOW61_13935	COG5416	Lipopolysaccharide assembly protein A domain
JOW61_13940	COG0490	domain, Protein
JOW61_13945	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JOW61_13945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JOW61_13955	COG2244	polysaccharide biosynthetic process
JOW61_13960	COG2323	membrane
JOW61_13970	COG1862	Preprotein translocase
JOW61_13975	COG0343	queuine tRNA-ribosyltransferase activity
JOW61_13980	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JOW61_13990	COG2255	four-way junction helicase activity
JOW61_13995	COG0632	four-way junction helicase activity
JOW61_14005	COG2814	Major facilitator Superfamily
JOW61_14010	COG0673	inositol 2-dehydrogenase activity
JOW61_14015	COG2112	serine threonine protein kinase
JOW61_14035	COG1115	amino acid carrier protein
JOW61_14040	COG0217	transcriptional regulatory protein
JOW61_14050	COG1388	LysM domain
JOW61_14055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JOW61_14060	COG0157	Belongs to the NadC ModD family
JOW61_14065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JOW61_14070	COG1104	cysteine desulfurase activity
JOW61_14075	COG1827	regulation of RNA biosynthetic process
JOW61_14080	COG0077	Prephenate dehydratase
JOW61_14085	COG4492	Belongs to the UPF0735 family
JOW61_14090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JOW61_14095	COG3290	protein histidine kinase activity
JOW61_14105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JOW61_14110	COG2868	ribosomal protein
JOW61_14115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JOW61_14120	COG1994	Peptidase M50
JOW61_14125	COG0739	heme binding
JOW61_14130	COG2894	cell division
JOW61_14135	COG0850	regulation of cytokinetic process
JOW61_14140	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JOW61_14150	COG1077	Cell shape determining protein MreB Mrl
JOW61_14155	COG2003	Belongs to the UPF0758 family
JOW61_14160	COG0424	maF-like protein
JOW61_14170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JOW61_14175	COG0285	dihydrofolate synthase activity
JOW61_14180	COG0525	valine-tRNA ligase activity
JOW61_14190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOW61_14195	COG1388	LysM domain
JOW61_14200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JOW61_14205	COG0113	porphobilinogen synthase activity
JOW61_14210	COG1587	Uroporphyrinogen-III synthase
JOW61_14215	COG0181	hydroxymethylbilane synthase activity
JOW61_14220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JOW61_14225	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JOW61_14235	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JOW61_14240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JOW61_14245	COG0470	DNA polymerase III
JOW61_14245	COG1067	ATP-dependent peptidase activity
JOW61_14250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JOW61_14255	COG0544	peptidyl-prolyl cis-trans isomerase activity
JOW61_14260	COG1477	protein flavinylation
JOW61_14260	COG0457	Tetratricopeptide repeat
JOW61_14265	COG0066	3-isopropylmalate dehydratase activity
JOW61_14270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOW61_14275	COG0473	3-isopropylmalate dehydrogenase activity
JOW61_14280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JOW61_14285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JOW61_14290	COG0440	acetolactate synthase activity
JOW61_14295	COG0028	Belongs to the TPP enzyme family
JOW61_14310	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
JOW61_14335	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JOW61_14365	COG0622	Phosphoesterase
JOW61_14370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JOW61_14375	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JOW61_14380	COG5401	PFAM Sporulation and spore germination
JOW61_14385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JOW61_14390	COG1846	Transcriptional regulator
JOW61_14395	COG2197	response regulator
JOW61_14400	COG0824	Thioesterase
JOW61_14405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JOW61_14410	COG1053	succinate dehydrogenase
JOW61_14415	COG2009	succinate dehydrogenase
JOW61_14420	COG1719	4-vinyl reductase, 4VR
JOW61_14425	COG0527	aspartate kinase activity
JOW61_14430	COG0322	excinuclease ABC activity
JOW61_14435	COG3118	belongs to the thioredoxin family
JOW61_14440	COG3534	alpha-L-arabinofuranosidase
JOW61_14445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JOW61_14450	COG2086	electron transfer activity
JOW61_14455	COG1024	Enoyl-CoA hydratase
JOW61_14460	COG1309	transcriptional regulator
JOW61_14465	COG0318	PFAM AMP-dependent synthetase and ligase
JOW61_14470	COG3766	membrane
JOW61_14475	COG1193	negative regulation of DNA recombination
JOW61_14480	COG1796	DNA polymerase
JOW61_14480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JOW61_14485	COG1286	toxin biosynthetic process
JOW61_14490	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JOW61_14495	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOW61_14500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOW61_14500	COG0072	phenylalanine-tRNA ligase activity
JOW61_14505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JOW61_14515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOW61_14525	COG3835	regulator
JOW61_14530	COG0277	FAD linked oxidase domain protein
JOW61_14535	COG0247	lactate metabolic process
JOW61_14540	COG0346	lactoylglutathione lyase activity
JOW61_14545	COG1966	Carbon starvation protein
JOW61_14550	COG3534	alpha-L-arabinofuranosidase
JOW61_14555	COG0395	ABC-type sugar transport system, permease component
JOW61_14560	COG1175	transmembrane transport
JOW61_14565	COG1653	transport
JOW61_14570	COG0371	Dehydrogenase
JOW61_14575	COG0647	UMP catabolic process
JOW61_14580	COG0235	Class ii aldolase
JOW61_14585	COG1069	ribulokinase activity
JOW61_14590	COG2160	L-arabinose isomerase activity
JOW61_14600	COG1363	Peptidase, m42
JOW61_14610	COG3326	Membrane
JOW61_14615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JOW61_14620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JOW61_14625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOW61_14635	COG1346	cytolysis
JOW61_14640	COG1380	Effector of murein hydrolase LrgA
JOW61_14645	COG3279	Response regulator of the LytR AlgR family
JOW61_14650	COG3275	phosphorelay sensor kinase activity
JOW61_14655	COG1011	Hydrolase
JOW61_14660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOW61_14670	COG0398	Pfam SNARE associated Golgi protein
JOW61_14675	COG1484	DNA-dependent DNA replication
JOW61_14680	COG3611	Membrane attachment protein
JOW61_14685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JOW61_14690	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JOW61_14695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JOW61_14700	COG1733	regulation of RNA biosynthetic process
JOW61_14705	COG2814	Major facilitator Superfamily
JOW61_14710	COG0656	L-ascorbic acid biosynthetic process
JOW61_14715	COG0237	dephospho-CoA kinase activity
JOW61_14720	COG1971	Probably functions as a manganese efflux pump
JOW61_14725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JOW61_14730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOW61_14730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOW61_14735	COG5002	protein histidine kinase activity
JOW61_14740	COG0745	RESPONSE REGULATOR receiver
JOW61_14745	COG0039	L-malate dehydrogenase activity
JOW61_14750	COG0538	isocitrate dehydrogenase activity
JOW61_14755	COG0372	Belongs to the citrate synthase family
JOW61_14760	COG2707	UPF0756 membrane protein
JOW61_14765	COG0628	permease
JOW61_14770	COG3030	protein affecting phage T7 exclusion by the F plasmid
JOW61_14775	COG0469	pyruvate kinase activity
JOW61_14780	COG0205	6-phosphofructokinase activity
JOW61_14785	COG0825	malonyl-CoA metabolic process
JOW61_14790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JOW61_14795	COG0281	malic enzyme
JOW61_14800	COG0587	DNA-directed DNA polymerase activity
JOW61_14820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JOW61_14830	COG4109	DRTGG domain
JOW61_14840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JOW61_14845	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_14850	COG0165	Argininosuccinate lyase
JOW61_14855	COG0137	argininosuccinate synthase activity
JOW61_14860	COG0521	Mo-molybdopterin cofactor biosynthetic process
JOW61_14865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOW61_14875	COG0827	DNA restriction-modification system
JOW61_14880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JOW61_14885	COG3874	Sporulation protein YtfJ
JOW61_14895	COG1714	RDD family
JOW61_14900	COG0616	signal peptide processing
JOW61_14905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOW61_14910	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JOW61_14915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JOW61_14925	COG0301	tRNA thio-modification
JOW61_14930	COG1104	cysteine desulfurase activity
JOW61_14935	COG1114	Component of the transport system for branched-chain amino acids
JOW61_14940	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JOW61_14945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JOW61_14950	COG1309	transcriptional regulator
JOW61_14955	COG1956	GAF domain-containing protein
JOW61_14960	COG2203	Gaf domain
JOW61_14960	COG2199	diguanylate cyclase activity
JOW61_14965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JOW61_14970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOW61_14975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JOW61_14980	COG0454	-acetyltransferase
JOW61_14985	COG0517	IMP dehydrogenase activity
JOW61_14990	COG0123	including yeast histone deacetylase and acetoin utilization protein
JOW61_14995	COG1360	Flagellar Motor Protein
JOW61_15000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JOW61_15005	COG1609	Transcriptional regulator
JOW61_15010	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JOW61_15010	COG1605	Chorismate mutase
JOW61_15015	COG3118	belongs to the thioredoxin family
JOW61_15020	COG4980	gas vesicle protein
JOW61_15025	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOW61_15030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JOW61_15035	COG1674	ftsk spoiiie
JOW61_15040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOW61_15045	COG4848	Belongs to the UPF0354 family
JOW61_15050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_15065	COG1363	Peptidase, m42
JOW61_15070	COG5584	Small secreted protein
JOW61_15075	COG0281	malic enzyme
JOW61_15080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JOW61_15085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JOW61_15095	COG0510	thiamine kinase activity
JOW61_15100	COG1523	belongs to the glycosyl hydrolase 13 family
JOW61_15105	COG1597	lipid kinase activity
JOW61_15115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JOW61_15120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JOW61_15125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOW61_15130	COG2252	PERMEase
JOW61_15135	COG4473	ABC transporter
JOW61_15140	COG1131	(ABC) transporter
JOW61_15145	COG1349	DNA-binding transcription factor activity
JOW61_15150	COG1187	pseudouridine synthase activity
JOW61_15155	COG2244	polysaccharide biosynthetic process
JOW61_15160	COG2081	HI0933 family
JOW61_15165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JOW61_15185	COG1653	transport
JOW61_15190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JOW61_15195	COG4209	transmembrane transport
JOW61_15205	COG1653	transport
JOW61_15210	COG0395	ABC-type sugar transport system, permease component
JOW61_15215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JOW61_15220	COG2124	cytochrome p450
JOW61_15240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JOW61_15250	COG1073	alpha beta
JOW61_15255	COG1609	Transcriptional regulator
JOW61_15260	COG1653	transport
JOW61_15265	COG1175	transmembrane transport
JOW61_15270	COG0395	ABC-type sugar transport system, permease component
JOW61_15275	COG1486	melibiose metabolic process
JOW61_15280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOW61_15285	COG0495	leucyl-tRNA aminoacylation
JOW61_15295	COG1366	Belongs to the anti-sigma-factor antagonist family
JOW61_15295	COG2202	Pas domain
JOW61_15300	COG2814	Major facilitator Superfamily
JOW61_15305	COG2433	Pfam Transposase IS66
JOW61_15310	COG0577	efflux transmembrane transporter activity
JOW61_15315	COG1136	(ABC) transporter
JOW61_15320	COG2205	protein histidine kinase activity
JOW61_15325	COG0745	RESPONSE REGULATOR receiver
JOW61_15330	COG0577	efflux transmembrane transporter activity
JOW61_15335	COG1136	(ABC) transporter
JOW61_15350	COG1131	(ABC) transporter
JOW61_15355	COG1725	Transcriptional regulator
JOW61_15370	COG1242	4 iron, 4 sulfur cluster binding
JOW61_15375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JOW61_15385	COG2267	carboxylic ester hydrolase activity
JOW61_15390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JOW61_15395	COG1113	amino acid transport
JOW61_15400	COG0367	asparagine synthase
JOW61_15405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JOW61_15410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JOW61_15420	COG1506	peptidase
JOW61_15425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JOW61_15430	COG1116	anion transmembrane transporter activity
JOW61_15435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JOW61_15440	COG0494	nUDIX hydrolase
JOW61_15445	COG4824	toxin secretion phage lysis holin
JOW61_15450	COG0783	Belongs to the Dps family
JOW61_15465	COG1854	S-ribosylhomocysteine lyase activity
JOW61_15470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JOW61_15475	COG0288	reversible hydration of carbon dioxide
JOW61_15480	COG0254	rRNA binding
JOW61_15485	COG1271	oxidase subunit
JOW61_15490	COG1294	oxidase, subunit
JOW61_15500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JOW61_15505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JOW61_15505	COG1321	iron dependent repressor
JOW61_15510	COG1121	(ABC) transporter
JOW61_15515	COG0803	Belongs to the bacterial solute-binding protein 9 family
JOW61_15520	COG4948	Mandelate Racemase Muconate Lactonizing
JOW61_15525	COG0318	PFAM AMP-dependent synthetase and ligase
JOW61_15530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JOW61_15535	COG0596	Alpha beta hydrolase
JOW61_15540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JOW61_15545	COG1169	isochorismate synthase
JOW61_15550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JOW61_15555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JOW61_15560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOW61_15565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JOW61_15570	COG0438	transferase activity, transferring glycosyl groups
JOW61_15580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOW61_15585	COG0438	transferase activity, transferring glycosyl groups
JOW61_15590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOW61_15595	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JOW61_15600	COG0058	SHG alpha-glucan phosphorylase activity
JOW61_15605	COG0297	glycogen (starch) synthase activity
JOW61_15610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JOW61_15615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JOW61_15620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JOW61_15745	COG3859	Proton-coupled thiamine transporter YuaJ
JOW61_15750	COG1247	-acetyltransferase
JOW61_15755	COG2268	Band 7 protein
JOW61_15760	COG1585	Membrane protein implicated in regulation of membrane protease activity
JOW61_15765	COG2318	DinB family
JOW61_15775	COG1454	alcohol dehydrogenase
JOW61_15780	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_15785	COG1510	regulation of RNA biosynthetic process
JOW61_15795	COG0569	domain protein
JOW61_15800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JOW61_15805	COG4682	membrane
JOW61_15810	COG1705	Flagellar rod assembly protein muramidase FlgJ
JOW61_15815	COG0477	Major facilitator Superfamily
JOW61_15820	COG5553	Cysteine dioxygenase type I
JOW61_15830	COG1968	undecaprenyl-diphosphatase activity
JOW61_15835	COG0628	permease
JOW61_15840	COG0673	inositol 2-dehydrogenase activity
JOW61_15845	COG4806	L-rhamnose isomerase
JOW61_15850	COG3254	rhamnose metabolic process
JOW61_15855	COG1070	Carbohydrate kinase
JOW61_15860	COG1349	DNA-binding transcription factor activity
JOW61_15865	COG3347	Dehydrogenase
JOW61_15865	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_15875	COG0840	transmembrane signaling receptor activity
JOW61_15885	COG0840	transmembrane signaling receptor activity
JOW61_15900	COG0432	Pfam Uncharacterised protein family UPF0047
JOW61_15910	COG0366	Alpha amylase catalytic
JOW61_15915	COG1253	flavin adenine dinucleotide binding
JOW61_15920	COG2738	Putative neutral zinc metallopeptidase
JOW61_15935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JOW61_15950	COG0166	Belongs to the GPI family
JOW61_15955	COG1979	alcohol dehydrogenase
JOW61_15960	COG1979	alcohol dehydrogenase
JOW61_15965	COG2155	Conserved Protein
JOW61_15970	COG1098	S1 RNA binding domain
JOW61_15975	COG0436	Aminotransferase
JOW61_15980	COG1522	sequence-specific DNA binding
JOW61_15985	COG2267	carboxylic ester hydrolase activity
JOW61_15995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JOW61_16000	COG2205	protein histidine kinase activity
JOW61_16010	COG5018	Exonuclease
JOW61_16015	COG2814	Major facilitator Superfamily
JOW61_16020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JOW61_16025	COG3011	Protein conserved in bacteria
JOW61_16035	COG3290	protein histidine kinase activity
JOW61_16040	COG4565	transcriptional regulatory protein
JOW61_16045	COG1744	ABC transporter substrate-binding protein PnrA-like
JOW61_16050	COG3845	ABC transporter
JOW61_16055	COG4603	Belongs to the binding-protein-dependent transport system permease family
JOW61_16060	COG1079	Belongs to the binding-protein-dependent transport system permease family
JOW61_16065	COG3493	citrate carrier protein
JOW61_16075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JOW61_16075	COG2111	Na H antiporter
JOW61_16080	COG2111	Na H antiporter
JOW61_16085	COG1006	Multisubunit Na H antiporter MnhC subunit
JOW61_16090	COG0651	ATP synthesis coupled electron transport
JOW61_16095	COG1863	multisubunit Na H antiporter MnhE subunit
JOW61_16100	COG2212	antiporter activity
JOW61_16105	COG1320	monovalent cation:proton antiporter activity
JOW61_16110	COG2050	protein possibly involved in aromatic compounds catabolism
JOW61_16115	COG2197	response regulator
JOW61_16120	COG4585	Histidine kinase
JOW61_16130	COG0142	geranyltranstransferase activity
JOW61_16150	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JOW61_16155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JOW61_16160	COG1335	isochorismatase
JOW61_16165	COG5506	Protein of unknown function (DUF1694)
JOW61_16180	COG0628	permease
JOW61_16195	COG1418	mRNA catabolic process
JOW61_16200	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_16210	COG1511	domain protein
JOW61_16215	COG1674	ftsk spoiiie
JOW61_16215	COG0433	COG0433 Predicted ATPase
JOW61_16220	COG4499	WXG100 protein secretion system (Wss), protein YukC
JOW61_16225	COG5417	Belongs to the EsaB family
JOW61_16230	COG4842	Belongs to the WXG100 family
JOW61_16235	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JOW61_16235	COG2508	Transcriptional regulator
JOW61_16240	COG0686	Belongs to the AlaDH PNT family
JOW61_16245	COG5634	Uncharacterized conserved protein (DUF2278)
JOW61_16250	COG3251	PFAM MbtH domain protein
JOW61_16255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JOW61_16260	COG3433	isochorismatase activity
JOW61_16260	COG1535	isochorismatase
JOW61_16265	COG1021	2,3-dihydroxybenzoate-AMP ligase
JOW61_16270	COG1169	isochorismate synthase
JOW61_16275	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_16280	COG2819	hydrolase of the alpha beta superfamily
JOW61_16285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JOW61_16290	COG1268	BioY protein
JOW61_16295	COG2056	Na+-H+ antiporter family
JOW61_16300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JOW61_16305	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JOW61_16310	COG3584	3D domain protein
JOW61_16325	COG1252	NADH dehydrogenase
JOW61_16330	COG0492	ferredoxin-NADP+ reductase activity
JOW61_16340	COG0516	GMP reductase activity
JOW61_16345	COG2808	Putative FMN-binding domain
JOW61_16350	COG0456	acetyltransferase
JOW61_16460	COG0582	viral genome integration into host DNA
JOW61_16470	COG4974	Belongs to the 'phage' integrase family
JOW61_16475	COG0316	Belongs to the HesB IscA family
JOW61_16480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JOW61_16485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOW61_16490	COG4844	belongs to the
JOW61_16495	COG1252	NADH dehydrogenase
JOW61_16500	COG4837	Protein of unknown function (DUF1462)
JOW61_16505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JOW61_16510	COG4946	Tricorn protease homolog
JOW61_16510	COG1506	peptidase
JOW61_16510	COG0823	Involved in the tonB-independent uptake of proteins
JOW61_16515	COG0083	homoserine kinase activity
JOW61_16520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JOW61_16525	COG0460	homoserine dehydrogenase
JOW61_16530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOW61_16535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JOW61_16540	COG0647	UMP catabolic process
JOW61_16545	COG2445	Protein of unknown function DUF86
JOW61_16550	COG4470	Protein conserved in bacteria
JOW61_16560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JOW61_16565	COG0739	heme binding
JOW61_16575	COG3377	Domain of unknown function (DUF1805)
JOW61_16580	COG0737	Belongs to the 5'-nucleotidase family
JOW61_16585	COG0730	response to heat
JOW61_16590	COG1801	Protein of unknown function DUF72
JOW61_16600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JOW61_16605	COG2508	Transcriptional regulator
JOW61_16610	COG2233	PERMEase
JOW61_16615	COG2233	PERMEase
JOW61_16620	COG3195	allantoin biosynthetic process
JOW61_16620	COG3648	Uricase
JOW61_16625	COG2351	hydroxyisourate hydrolase activity
JOW61_16635	COG2080	2 iron, 2 sulfur cluster binding
JOW61_16640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JOW61_16645	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JOW61_16650	COG2068	MobA-Related Protein
JOW61_16655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JOW61_16660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JOW61_16665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JOW61_16675	COG2356	endonuclease I
JOW61_16680	COG3842	ATPase activity
JOW61_16685	COG2188	Transcriptional regulator
JOW61_16690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOW61_16700	COG1175	transmembrane transport
JOW61_16705	COG1653	transport
JOW61_16710	COG2222	sugar isomerase
JOW61_16715	COG0322	excinuclease ABC activity
JOW61_16720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JOW61_16735	COG0346	lactoylglutathione lyase activity
JOW61_16740	COG0640	Transcriptional regulator
JOW61_16745	COG0719	Fe-S assembly protein
JOW61_16750	COG0822	iron-sulfur transferase activity
JOW61_16755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOW61_16760	COG0719	Fe-S assembly protein
JOW61_16765	COG0396	ATPase activity
JOW61_16780	COG1464	Belongs to the NlpA lipoprotein family
JOW61_16785	COG2011	ABC-type metal ion transport system permease component
JOW61_16790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JOW61_16800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JOW61_16805	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JOW61_16815	COG0509	glycine decarboxylation via glycine cleavage system
JOW61_16820	COG1393	Belongs to the ArsC family
JOW61_16825	COG1960	acyl-CoA dehydrogenase activity
JOW61_16830	COG0183	Belongs to the thiolase family
JOW61_16835	COG1250	3-hydroxyacyl-CoA dehydrogenase
JOW61_16835	COG1024	Enoyl-CoA hydratase
JOW61_16855	COG5577	PFAM Coat F domain
JOW61_16860	COG1846	Transcriptional regulator
JOW61_16865	COG0477	Major facilitator Superfamily
JOW61_16870	COG1942	4-Oxalocrotonate Tautomerase
JOW61_16875	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_16880	COG0583	DNA-binding transcription factor activity
JOW61_16890	COG1120	ATPase activity
JOW61_16910	COG1131	(ABC) transporter
JOW61_16955	COG0783	Belongs to the Dps family
JOW61_16960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOW61_16965	COG0745	RESPONSE REGULATOR receiver
JOW61_16970	COG2770	Histidine kinase
JOW61_16970	COG2205	protein histidine kinase activity
JOW61_16980	COG1309	transcriptional regulator
JOW61_16985	COG0114	fumarate hydratase activity
JOW61_16995	COG0697	spore germination
JOW61_17000	COG0814	amino acid
JOW61_17010	COG2197	response regulator
JOW61_17015	COG4585	Histidine kinase
JOW61_17020	COG4758	membrane
JOW61_17025	COG3595	metallopeptidase activity
JOW61_17030	COG1842	Phage shock protein A
JOW61_17035	COG4758	membrane
JOW61_17040	COG2814	Major facilitator Superfamily
JOW61_17045	COG2096	Adenosyltransferase
JOW61_17050	COG1120	ATPase activity
JOW61_17055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_17060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JOW61_17065	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_17070	COG3386	PFAM SMP-30 Gluconolaconase
JOW61_17075	COG2205	protein histidine kinase activity
JOW61_17080	COG0745	RESPONSE REGULATOR receiver
JOW61_17100	COG2140	Oxalate decarboxylase
JOW61_17110	COG0577	efflux transmembrane transporter activity
JOW61_17115	COG1136	(ABC) transporter
JOW61_17120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOW61_17125	COG1120	ATPase activity
JOW61_17130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_17135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOW61_17140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JOW61_17145	COG0531	amino acid
JOW61_17155	COG1988	membrane-bound metal-dependent
JOW61_17160	COG1368	sulfuric ester hydrolase activity
JOW61_17165	COG1910	domain protein
JOW61_17170	COG0725	ABC transporter, periplasmic molybdate-binding protein
JOW61_17175	COG4149	molybdate abc transporter
JOW61_17180	COG0656	L-ascorbic acid biosynthetic process
JOW61_17190	COG0025	NhaP-type Na H and K H
JOW61_17195	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOW61_17200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOW61_17205	COG3973	AAA domain
JOW61_17215	COG2860	membrane
JOW61_17220	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JOW61_17225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JOW61_17230	COG2217	Heavy metal translocating P-type atpase
JOW61_17235	COG2217	Heavy metal translocating P-type atpase
JOW61_17240	COG2608	mercury ion transmembrane transporter activity
JOW61_17245	COG1937	Protein conserved in bacteria
JOW61_17250	COG0673	inositol 2-dehydrogenase activity
JOW61_17260	COG1289	transmembrane transporter activity
JOW61_17270	COG2076	Multidrug Resistance protein
JOW61_17275	COG1309	transcriptional regulator
JOW61_17280	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_17290	COG5444	nuclease activity
JOW61_17305	COG5632	N-Acetylmuramoyl-L-alanine amidase
JOW61_17305	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_17310	COG4824	toxin secretion phage lysis holin
JOW61_17335	COG3942	CHAP domain
JOW61_17335	COG1705	Flagellar rod assembly protein muramidase FlgJ
JOW61_17575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JOW61_17580	COG0557	exoribonuclease II activity
JOW61_17585	COG1647	Serine aminopeptidase, S33
JOW61_17590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JOW61_17595	COG0596	Alpha beta hydrolase
JOW61_17600	COG1476	TRANSCRIPTIONal
JOW61_17605	COG1396	sequence-specific DNA binding
JOW61_17610	COG1396	sequence-specific DNA binding
JOW61_17615	COG1733	regulation of RNA biosynthetic process
JOW61_17620	COG0840	transmembrane signaling receptor activity
JOW61_17625	COG1174	glycine betaine transport
JOW61_17630	COG1732	Glycine betaine
JOW61_17635	COG1174	glycine betaine transport
JOW61_17640	COG0517	IMP dehydrogenase activity
JOW61_17640	COG1125	glycine betaine transport
JOW61_17645	COG1510	regulation of RNA biosynthetic process
JOW61_17650	COG1174	glycine betaine transport
JOW61_17655	COG1732	Glycine betaine
JOW61_17660	COG1174	glycine betaine transport
JOW61_17665	COG1125	glycine betaine transport
JOW61_17665	COG0517	IMP dehydrogenase activity
JOW61_17670	COG1510	regulation of RNA biosynthetic process
JOW61_17675	COG2095	MarC family integral membrane protein
JOW61_17685	COG3064	Membrane
JOW61_17690	COG4640	response to antibiotic
JOW61_17695	COG0456	acetyltransferase
JOW61_17700	COG0148	phosphopyruvate hydratase activity
JOW61_17705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JOW61_17710	COG0149	triose-phosphate isomerase activity
JOW61_17715	COG0126	phosphoglycerate kinase activity
JOW61_17720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JOW61_17725	COG2390	Transcriptional regulator
JOW61_17730	COG2814	Major facilitator Superfamily
JOW61_17735	COG1609	Transcriptional regulator
JOW61_17740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOW61_17745	COG0583	DNA-binding transcription factor activity
JOW61_17750	COG0697	spore germination
JOW61_17755	COG1113	amino acid transport
JOW61_17765	COG1556	Lactate utilization protein
JOW61_17770	COG1139	Iron-sulfur cluster binding protein
JOW61_17775	COG0247	lactate metabolic process
JOW61_17780	COG2197	response regulator
JOW61_17785	COG4585	Histidine kinase
JOW61_17790	COG0842	Transport permease protein
JOW61_17795	COG1131	(ABC) transporter
JOW61_17815	COG0596	Alpha beta hydrolase
JOW61_17820	COG2208	phosphoserine phosphatase activity
JOW61_17825	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JOW61_17830	COG1874	Beta-galactosidase
JOW61_17835	COG3833	ABC-type maltose transport systems, permease component
JOW61_17840	COG1175	transmembrane transport
JOW61_17845	COG2182	Extracellular solute-binding protein
JOW61_17850	COG1609	Transcriptional regulator
JOW61_17855	COG2186	Transcriptional regulator
JOW61_17860	COG1620	l-lactate permease
JOW61_17865	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JOW61_17875	COG5039	Polysaccharide pyruvyl transferase
JOW61_17880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JOW61_17885	COG0110	maltose O-acetyltransferase activity
JOW61_17890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JOW61_17895	COG2244	polysaccharide biosynthetic process
JOW61_17900	COG1216	Glycosyl transferase, family 2
JOW61_17905	COG5039	Polysaccharide pyruvyl transferase
JOW61_17910	COG1216	Glycosyl transferase, family 2
JOW61_17920	COG0438	transferase activity, transferring glycosyl groups
JOW61_17925	COG1215	transferase activity, transferring glycosyl groups
JOW61_17930	COG0438	transferase activity, transferring glycosyl groups
JOW61_17935	COG1086	Polysaccharide biosynthesis protein
JOW61_17940	COG0489	protein tyrosine kinase activity
JOW61_17945	COG3944	biosynthesis protein
JOW61_17950	COG1396	sequence-specific DNA binding
JOW61_17955	COG2272	Belongs to the type-B carboxylesterase lipase family
JOW61_17965	COG3479	Phenolic acid decarboxylase
JOW61_17980	COG1794	racemase activity, acting on amino acids and derivatives
JOW61_17990	COG1621	beta-fructofuranosidase activity
JOW61_17995	COG1621	beta-fructofuranosidase activity
JOW61_18000	COG0531	amino acid
JOW61_18005	COG1309	transcriptional regulator
JOW61_18010	COG2076	Multidrug Resistance protein
JOW61_18015	COG2076	Multidrug Resistance protein
JOW61_18035	COG1674	ftsk spoiiie
JOW61_18055	COG1388	LysM domain
JOW61_18055	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_18055	COG5632	N-Acetylmuramoyl-L-alanine amidase
JOW61_18090	COG1705	Flagellar rod assembly protein muramidase FlgJ
JOW61_18170	COG0582	viral genome integration into host DNA
JOW61_18280	COG4974	Belongs to the 'phage' integrase family
JOW61_18290	COG0740	serine-type endopeptidase activity
JOW61_18295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JOW61_18300	COG0366	Alpha amylase catalytic
JOW61_18305	COG1554	hydrolase, family 65, central catalytic
JOW61_18310	COG5521	maltodextrose utilization protein MalA
JOW61_18315	COG3833	ABC-type maltose transport systems, permease component
JOW61_18320	COG1175	transmembrane transport
JOW61_18325	COG2182	Extracellular solute-binding protein
JOW61_18335	COG1609	Transcriptional regulator
JOW61_18340	COG1611	Belongs to the LOG family
JOW61_18350	COG0659	secondary active sulfate transmembrane transporter activity
JOW61_18355	COG0288	reversible hydration of carbon dioxide
JOW61_18360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOW61_18365	COG0577	efflux transmembrane transporter activity
JOW61_18370	COG1136	(ABC) transporter
JOW61_18375	COG5002	protein histidine kinase activity
JOW61_18380	COG0745	RESPONSE REGULATOR receiver
JOW61_18390	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JOW61_18395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_18400	COG1481	regulation of sporulation
JOW61_18405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JOW61_18410	COG1660	Displays ATPase and GTPase activities
JOW61_18415	COG1051	belongs to the nudix hydrolase family
JOW61_18420	COG0492	ferredoxin-NADP+ reductase activity
JOW61_18425	COG0791	NLP P60 protein
JOW61_18425	COG3883	PFAM NLP P60 protein
JOW61_18430	COG0457	Tetratricopeptide repeat
JOW61_18435	COG1132	(ABC) transporter
JOW61_18455	COG0140	phosphoribosyl-ATP diphosphatase activity
JOW61_18455	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JOW61_18460	COG0107	imidazoleglycerol-phosphate synthase activity
JOW61_18465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JOW61_18470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JOW61_18475	COG0131	Imidazoleglycerol-phosphate dehydratase
JOW61_18480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JOW61_18485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JOW61_18490	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JOW61_18495	COG4990	cell redox homeostasis
JOW61_18500	COG5297	Belongs to the glycosyl hydrolase family 6
JOW61_18515	COG0546	phosphoglycolate phosphatase activity
JOW61_18520	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JOW61_18525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JOW61_18530	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JOW61_18535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOW61_18540	COG0363	glucosamine-6-phosphate deaminase activity
JOW61_18545	COG2188	Transcriptional regulator
JOW61_18550	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JOW61_18560	COG1950	PFAM Membrane protein of
JOW61_18565	COG1983	PspC domain protein
JOW61_18570	COG3595	metallopeptidase activity
JOW61_18585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOW61_18590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JOW61_18595	COG0556	nucleotide-excision repair
JOW61_18600	COG4897	Protein conserved in bacteria
JOW61_18605	COG0574	Belongs to the PEP-utilizing enzyme family
JOW61_18605	COG3848	Pyruvate phosphate dikinase
JOW61_18610	COG1309	transcriptional regulator
JOW61_18615	COG2814	Major facilitator Superfamily
JOW61_18620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOW61_18630	COG0793	Belongs to the peptidase S41A family
JOW61_18630	COG3409	Peptidoglycan-binding domain 1 protein
JOW61_18635	COG2177	Part of the ABC transporter FtsEX involved in
JOW61_18640	COG2884	Cell division ATP-binding protein ftsE
JOW61_18645	COG2010	Cytochrome c
JOW61_18650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOW61_18660	COG0653	protein targeting
JOW61_18665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JOW61_18680	COG1516	flagellar protein fliS
JOW61_18685	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JOW61_18690	COG1334	flagellar protein FlaG
JOW61_18695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOW61_18700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JOW61_18705	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JOW61_18715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOW61_18720	COG1256	bacterial-type flagellum assembly
JOW61_18720	COG4786	Flagellar basal body rod
JOW61_18725	COG3418	PFAM FlgN family protein
JOW61_18730	COG2747	anti-sigma28 factor FlgM
JOW61_18740	COG1040	competence protein
JOW61_18750	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JOW61_18755	COG1307	EDD domain protein, DegV family
JOW61_18760	COG2197	response regulator
JOW61_18765	COG4585	Histidine kinase
JOW61_18770	COG1739	Uncharacterized protein family UPF0029
JOW61_18775	COG1316	TRANSCRIPTIONal
JOW61_18805	COG1131	(ABC) transporter
JOW61_18815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JOW61_18820	COG0438	transferase activity, transferring glycosyl groups
JOW61_18825	COG1215	transferase activity, transferring glycosyl groups
JOW61_18830	COG3206	protein involved in exopolysaccharide biosynthesis
JOW61_18835	COG3307	-O-antigen
JOW61_18840	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOW61_18845	COG0438	transferase activity, transferring glycosyl groups
JOW61_18845	COG0297	glycogen (starch) synthase activity
JOW61_18850	COG2244	polysaccharide biosynthetic process
JOW61_18865	COG2247	cell wall binding repeat
JOW61_18865	COG0860	N-Acetylmuramoyl-L-alanine amidase
JOW61_18870	COG2247	cell wall binding repeat
JOW61_18870	COG2385	sporulation resulting in formation of a cellular spore
JOW61_18895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JOW61_18900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JOW61_18910	COG1134	teichoic acid transport
JOW61_18915	COG1682	transport, permease protein
JOW61_18930	COG0463	Glycosyl transferase, family 2
JOW61_18930	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOW61_18935	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOW61_18940	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JOW61_18945	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JOW61_18950	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOW61_18955	COG4193	domain, Protein
JOW61_18960	COG1482	cell wall glycoprotein biosynthetic process
JOW61_18965	COG0697	spore germination
JOW61_18970	COG0814	amino acid
JOW61_18985	COG1316	TRANSCRIPTIONal
JOW61_18990	COG0561	phosphatase activity
JOW61_18995	COG0791	NLP P60 protein
JOW61_19005	COG2843	Capsule synthesis protein
JOW61_19015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JOW61_19020	COG1609	Transcriptional regulator
JOW61_19025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOW61_19030	COG1869	D-ribose catabolic process
JOW61_19035	COG1129	ABC transporter
JOW61_19040	COG1172	Belongs to the binding-protein-dependent transport system permease family
JOW61_19045	COG1879	ABC-type sugar transport system periplasmic component
JOW61_19050	COG3103	Sh3 type 3 domain protein
JOW61_19060	COG2249	NAD(P)H dehydrogenase (quinone) activity
JOW61_19065	COG3527	Alpha-acetolactate decarboxylase
JOW61_19070	COG0028	Belongs to the TPP enzyme family
JOW61_19075	COG0583	DNA-binding transcription factor activity
JOW61_19080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOW61_19095	COG5337	Spore coat protein CotH
JOW61_19105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JOW61_19115	COG0405	Gamma-glutamyltransferase
JOW61_19120	COG1522	sequence-specific DNA binding
JOW61_19125	COG2059	Chromate
JOW61_19130	COG2059	Chromate
JOW61_19140	COG0655	NAD(P)H dehydrogenase (quinone) activity
JOW61_19145	COG0583	DNA-binding transcription factor activity
JOW61_19175	COG5444	nuclease activity
JOW61_19200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOW61_19205	COG4464	protein tyrosine phosphatase activity
JOW61_19210	COG0489	protein tyrosine kinase activity
JOW61_19215	COG3944	biosynthesis protein
JOW61_19225	COG4715	Zinc finger, swim domain protein
JOW61_19230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JOW61_19235	COG0561	phosphatase activity
JOW61_19240	COG1349	DNA-binding transcription factor activity
JOW61_19245	COG0629	single-stranded DNA binding
JOW61_19260	COG3764	Sortase (surface protein transpeptidase)
JOW61_19270	COG2972	Histidine kinase
JOW61_19270	COG0745	RESPONSE REGULATOR receiver
JOW61_19275	COG1970	mechanosensitive ion channel activity
JOW61_19280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JOW61_19285	COG0457	Tetratricopeptide repeat
JOW61_19290	COG4786	Flagellar basal body rod
JOW61_19295	COG4786	Flagellar basal body rod
JOW61_19300	COG1077	Cell shape determining protein MreB Mrl
JOW61_19305	COG1609	Transcriptional regulator
JOW61_19315	COG1846	Transcriptional regulator
JOW61_19320	COG2814	Major facilitator Superfamily
JOW61_19325	COG3420	alginic acid biosynthetic process
JOW61_19330	COG1953	Uracil, thiamine, allantoin
JOW61_19335	COG0477	Major facilitator Superfamily
JOW61_19340	COG1335	isochorismatase
JOW61_19350	COG0004	ammonium transporteR
JOW61_19355	COG0347	Belongs to the P(II) protein family
JOW61_19360	COG0671	phosphoesterase, PA-phosphatase related
JOW61_19370	COG0739	heme binding
JOW61_19375	COG1247	-acetyltransferase
JOW61_19385	COG2089	acid synthase
JOW61_19395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOW61_19400	COG0789	Transcriptional regulator
JOW61_19410	COG2910	NAD(P)H-binding
JOW61_19415	COG1959	2 iron, 2 sulfur cluster binding
JOW61_19420	COG0804	urea catabolic process
JOW61_19425	COG0832	Belongs to the urease beta subunit family
JOW61_19430	COG0831	urea catabolic process
JOW61_19445	COG3237	CsbD-like
JOW61_19450	COG1994	Peptidase M50
JOW61_19455	COG0457	Tetratricopeptide repeat
JOW61_19460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JOW61_19465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JOW61_19475	COG2304	oxidoreductase activity
JOW61_19485	COG2304	oxidoreductase activity
JOW61_19490	COG2385	sporulation resulting in formation of a cellular spore
JOW61_19495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOW61_19505	COG4836	Membrane
JOW61_19515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JOW61_19520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JOW61_19525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JOW61_19530	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JOW61_19535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOW61_19540	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JOW61_19550	COG0356	it plays a direct role in the translocation of protons across the membrane
JOW61_19560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JOW61_19565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JOW61_19570	COG4475	Protein of unknown function (DUF436)
JOW61_19575	COG0698	ribose 5-phosphate isomerase
JOW61_19580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOW61_19585	COG1971	Probably functions as a manganese efflux pump
JOW61_19590	COG0009	L-threonylcarbamoyladenylate synthase
JOW61_19595	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JOW61_19615	COG2890	protein-(glutamine-N5) methyltransferase activity
JOW61_19620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JOW61_19625	COG0346	lactoylglutathione lyase activity
JOW61_19630	COG0789	Transcriptional regulator
JOW61_19635	COG0679	Auxin Efflux Carrier
JOW61_19640	COG0281	malic enzyme
JOW61_19645	COG1435	thymidine kinase activity
JOW61_19655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JOW61_19665	COG1494	fructose-1,6-bisphosphatase
JOW61_19670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOW61_19680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JOW61_19685	COG0191	fructose-bisphosphate aldolase activity
JOW61_19690	COG2204	response regulator
JOW61_19695	COG4821	SIS domain
JOW61_19700	COG0504	CTP synthase activity
JOW61_19705	COG3343	RNA polymerase activity
JOW61_19710	COG1960	acyl-CoA dehydrogenase activity
JOW61_19715	COG0247	lactate metabolic process
JOW61_19715	COG2181	nitrate reductase activity
JOW61_19720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOW61_19725	COG4294	response to UV
JOW61_19735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOW61_19745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOW61_19755	COG2181	nitrate reductase activity
JOW61_19760	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JOW61_19765	COG1140	nitrate reductase beta subunit
JOW61_19770	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOW61_19775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JOW61_19785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JOW61_19790	COG2223	nitrite transmembrane transporter activity
JOW61_19795	COG0018	arginyl-trna synthetase
JOW61_19800	COG4506	Protein conserved in bacteria
JOW61_19815	COG0535	radical SAM domain protein
JOW61_19825	COG1131	(ABC) transporter
JOW61_19830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JOW61_19835	COG0612	Peptidase, M16
JOW61_19840	COG0612	Peptidase, M16
JOW61_19850	COG3391	amine dehydrogenase activity
JOW61_19855	COG3391	amine dehydrogenase activity
JOW61_19860	COG0457	Tetratricopeptide repeat
JOW61_19870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOW61_19875	COG0010	Belongs to the arginase family
JOW61_19880	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JOW61_19885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JOW61_19900	COG1994	Peptidase M50
JOW61_19905	COG1942	4-Oxalocrotonate Tautomerase
JOW61_19910	COG1846	Transcriptional regulator
JOW61_19915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOW61_19920	COG0477	Major facilitator Superfamily
JOW61_19925	COG1959	2 iron, 2 sulfur cluster binding
JOW61_19930	COG3465	dGTPase activity
JOW61_19935	COG1078	dGTPase activity
JOW61_19940	COG4844	belongs to the
JOW61_19950	COG0697	spore germination
JOW61_19955	COG0095	Lipoate-protein ligase
JOW61_19960	COG0583	DNA-binding transcription factor activity
JOW61_19965	COG0280	phosphate acetyltransferase
JOW61_19970	COG3253	May function as heme-dependent peroxidase
JOW61_19975	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_19980	COG0436	Aminotransferase
JOW61_19985	COG2814	Major facilitator Superfamily
JOW61_19990	COG0151	Belongs to the GarS family
JOW61_19995	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_20000	COG1917	Cupin 2, conserved barrel domain protein
JOW61_20005	COG0077	Prephenate dehydratase
JOW61_20010	COG2814	Major facilitator Superfamily
JOW61_20015	COG0833	amino acid
JOW61_20020	COG4187	Peptidase family M20/M25/M40
JOW61_20025	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_20030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JOW61_20040	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JOW61_20045	COG1091	dTDP-4-dehydrorhamnose reductase activity
JOW61_20050	COG1088	dTDP-glucose 4,6-dehydratase activity
JOW61_20055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JOW61_20060	COG3980	spore coat polysaccharide biosynthesis protein
JOW61_20065	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JOW61_20070	COG2089	acid synthase
JOW61_20075	COG0456	acetyltransferase
JOW61_20080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JOW61_20085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOW61_20090	COG0463	Glycosyl transferase, family 2
JOW61_20100	COG2363	Small membrane protein
JOW61_20105	COG2233	PERMEase
JOW61_20115	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_20120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JOW61_20125	COG1216	Glycosyl transferase, family 2
JOW61_20130	COG0351	phosphomethylpyrimidine kinase
JOW61_20140	COG1621	beta-fructofuranosidase activity
JOW61_20145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_20145	COG1263	PTS System
JOW61_20150	COG2116	formate transmembrane transporter activity
JOW61_20165	COG1404	Belongs to the peptidase S8 family
JOW61_20170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOW61_20175	COG0778	Nitroreductase
JOW61_20180	COG0772	Belongs to the SEDS family
JOW61_20195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JOW61_20200	COG1845	cytochrome c oxidase, subunit III
JOW61_20205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOW61_20210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JOW61_20215	COG2261	transglycosylase associated protein
JOW61_20220	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JOW61_20225	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JOW61_20230	COG2246	polysaccharide biosynthetic process
JOW61_20235	COG1309	transcriptional regulator
JOW61_20245	COG3162	membrane
JOW61_20250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOW61_20255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JOW61_20260	COG2837	iron assimilation
JOW61_20265	COG2822	iron ion transport
JOW61_20270	COG0672	)-iron permease
JOW61_20275	COG0352	thiamine-phosphate diphosphorylase activity
JOW61_20280	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JOW61_20285	COG0583	DNA-binding transcription factor activity
JOW61_20290	COG1380	Effector of murein hydrolase LrgA
JOW61_20295	COG1346	cytolysis
JOW61_20300	COG2814	Major facilitator Superfamily
JOW61_20305	COG4895	conserved protein (DUF2196)
JOW61_20310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JOW61_20315	COG0346	lactoylglutathione lyase activity
JOW61_20325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JOW61_20335	COG1263	PTS System
JOW61_20335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_20340	COG3711	transcriptional antiterminator
JOW61_20345	COG1442	glycosyl transferase family 8
JOW61_20350	COG5522	Integral membrane protein (intg_mem_TP0381)
JOW61_20355	COG1846	Transcriptional regulator
JOW61_20360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOW61_20365	COG2234	aminopeptidase activity
JOW61_20370	COG2357	RelA SpoT domain protein
JOW61_20380	COG1575	Belongs to the MenA family. Type 1 subfamily
JOW61_20395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JOW61_20400	COG1696	Membrane protein involved in D-alanine export
JOW61_20405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOW61_20410	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JOW61_20420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JOW61_20425	COG1486	melibiose metabolic process
JOW61_20430	COG1447	Phosphotransferase system cellobiose-specific component IIA
JOW61_20435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JOW61_20440	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JOW61_20445	COG3711	transcriptional antiterminator
JOW61_20445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JOW61_20455	COG2094	Belongs to the DNA glycosylase MPG family
JOW61_20460	COG0753	catalase activity
JOW61_20465	COG2814	Major facilitator Superfamily
JOW61_20470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JOW61_20475	COG1131	(ABC) transporter
JOW61_20495	COG1595	DNA-templated transcription, initiation
JOW61_20500	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JOW61_20505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JOW61_20510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JOW61_20515	COG4988	ABC transporter
JOW61_20520	COG1294	oxidase, subunit
JOW61_20525	COG1271	oxidase subunit
JOW61_20530	COG3493	citrate carrier protein
JOW61_20535	COG0501	Belongs to the peptidase M48B family
JOW61_20545	COG0726	polysaccharide deacetylase
JOW61_20550	COG3842	ATPase activity
JOW61_20555	COG2508	Transcriptional regulator
JOW61_20560	COG1012	belongs to the aldehyde dehydrogenase family
JOW61_20565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOW61_20570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JOW61_20580	COG4585	Histidine kinase
JOW61_20585	COG2197	response regulator
JOW61_20590	COG2195	Cleaves the N-terminal amino acid of tripeptides
JOW61_20600	COG4894	glucomannan catabolic process
JOW61_20605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JOW61_20610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JOW61_20615	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_20620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JOW61_20625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOW61_20630	COG2610	gluconate transmembrane transporter activity
JOW61_20635	COG0500	methyltransferase
JOW61_20640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOW61_20655	COG0753	catalase activity
JOW61_20655	COG0693	protein deglycase activity
JOW61_20660	COG2851	Citrate transporter
JOW61_20665	COG2273	Hydrolase Family 16
JOW61_20670	COG3711	transcriptional antiterminator
JOW61_20680	COG2270	Major facilitator Superfamily
JOW61_20685	COG0513	Belongs to the DEAD box helicase family
JOW61_20690	COG2755	lipolytic protein G-D-S-L family
JOW61_20690	COG3401	FG-GAP repeat protein
JOW61_20815	COG0589	response to stress
JOW61_20825	COG2190	(PTS) system
JOW61_20825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JOW61_20825	COG1263	PTS System
JOW61_20845	COG5444	nuclease activity
JOW61_20865	COG0494	nUDIX hydrolase
JOW61_20870	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JOW61_20875	COG3507	Belongs to the glycosyl hydrolase 43 family
JOW61_20890	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JOW61_20895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOW61_20900	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JOW61_20905	COG2390	Transcriptional regulator
JOW61_20915	COG3192	ethanolamine utilization protein
JOW61_20920	COG2079	MmgE PrpD family protein
JOW61_20925	COG1473	amidohydrolase
JOW61_20930	COG1126	abc transporter atp-binding protein
JOW61_20935	COG0765	amino acid transport
JOW61_20940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JOW61_20945	COG0456	acetyltransferase
JOW61_20950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOW61_20955	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JOW61_20960	COG0561	phosphatase activity
JOW61_20990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JOW61_20995	COG5294	Protein conserved in bacteria
JOW61_21010	COG2205	protein histidine kinase activity
JOW61_21015	COG0745	RESPONSE REGULATOR receiver
JOW61_21020	COG0191	fructose-bisphosphate aldolase activity
JOW61_21025	COG1082	Xylose isomerase domain protein TIM barrel
JOW61_21030	COG1082	Xylose isomerase domain protein TIM barrel
JOW61_21035	COG0673	inositol 2-dehydrogenase activity
JOW61_21040	COG2814	Major facilitator Superfamily
JOW61_21045	COG1082	Xylose isomerase domain protein TIM barrel
JOW61_21050	COG3962	Belongs to the TPP enzyme family
JOW61_21055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOW61_21075	COG1349	DNA-binding transcription factor activity
JOW61_21080	COG0667	Aldo Keto reductase
JOW61_21110	COG0326	Molecular chaperone. Has ATPase activity
JOW61_21165	COG1917	Cupin 2, conserved barrel domain protein
JOW61_21170	COG1309	transcriptional regulator
JOW61_21175	COG1028	Short-chain dehydrogenase reductase Sdr
JOW61_21180	COG1846	Transcriptional regulator
JOW61_21185	COG1380	Effector of murein hydrolase LrgA
JOW61_21190	COG1346	cytolysis
JOW61_21195	COG5039	Polysaccharide pyruvyl transferase
JOW61_21200	COG1929	Belongs to the glycerate kinase type-1 family
JOW61_21205	COG1802	Transcriptional regulator
JOW61_21210	COG1070	Carbohydrate kinase
JOW61_21215	COG2610	gluconate transmembrane transporter activity
JOW61_21220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOW61_21225	COG0450	alkyl hydroperoxide reductase
JOW61_21230	COG3634	alkyl hydroperoxide reductase activity
JOW61_21235	COG2723	6-phospho-beta-galactosidase activity
JOW61_21245	COG2188	Transcriptional regulator
JOW61_21255	COG1131	(ABC) transporter
JOW61_21260	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JOW61_21275	COG0071	Belongs to the small heat shock protein (HSP20) family
JOW61_21305	COG0210	DNA helicase
JOW61_21335	COG2963	transposase activity
JOW61_21370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JOW61_21385	COG1063	alcohol dehydrogenase
JOW61_21405	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JOW61_21410	COG0456	acetyltransferase
JOW61_21415	COG0457	Tetratricopeptide repeat
JOW61_21425	COG0010	Belongs to the arginase family
JOW61_21430	COG0833	amino acid
JOW61_21435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JOW61_21455	COG5658	integral membrane protein
JOW61_21460	COG0640	Transcriptional regulator
JOW61_21465	COG3829	transcription factor binding
JOW61_21480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOW61_21485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JOW61_21490	COG4853	Protein conserved in bacteria
JOW61_21495	COG4863	YycH protein
JOW61_21500	COG5002	protein histidine kinase activity
JOW61_21505	COG0745	RESPONSE REGULATOR receiver
JOW61_21535	COG0346	lactoylglutathione lyase activity
JOW61_21540	COG0305	Participates in initiation and elongation during chromosome replication
JOW61_21555	COG3093	addiction module antidote protein HigA
JOW61_21560	COG2807	transmembrane transport
JOW61_21565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOW61_21570	COG0359	binds to the 23S rRNA
JOW61_21575	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JOW61_21580	COG4241	membrane
JOW61_21595	COG1733	regulation of RNA biosynthetic process
JOW61_21600	COG1227	inorganic diphosphatase activity
JOW61_21615	COG2271	Major facilitator Superfamily
JOW61_21620	COG0789	Transcriptional regulator
JOW61_21620	COG4978	Transcriptional regulator
JOW61_21630	COG4319	ketosteroid isomerase
JOW61_21635	COG1357	PFAM Pentapeptide repeats (8 copies)
JOW61_21650	COG1846	Transcriptional regulator
JOW61_21655	COG2153	protein acetylation
JOW61_21660	COG2364	Membrane
JOW61_21665	COG0456	acetyltransferase
JOW61_21670	COG2315	Protein conserved in bacteria
JOW61_21675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOW61_21680	COG1331	Highly conserved protein containing a thioredoxin domain
JOW61_21685	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JOW61_21690	COG1331	Highly conserved protein containing a thioredoxin domain
JOW61_21695	COG1266	CAAX protease self-immunity
JOW61_21700	COG0477	Major facilitator Superfamily
JOW61_21700	COG2814	Major facilitator Superfamily
JOW61_21705	COG0346	lactoylglutathione lyase activity
JOW61_21710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JOW61_21715	COG0542	response to heat
JOW61_21730	COG0708	Exodeoxyribonuclease III
JOW61_21735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JOW61_21740	COG0629	single-stranded DNA binding
JOW61_21745	COG0360	Binds together with S18 to 16S ribosomal RNA
JOW61_21750	COG0012	GTP binding
JOW61_21755	COG0243	molybdopterin cofactor binding
JOW61_21760	COG4481	Protein conserved in bacteria
JOW61_21765	COG3949	Membrane
JOW61_21775	COG1475	DNA binding
JOW61_21780	COG1192	Involved in chromosome partitioning
JOW61_21790	COG1475	DNA binding
JOW61_21795	COG0357	Ribosomal RNA small subunit methyltransferase G
JOW61_21800	COG0445	tRNA wobble uridine modification
JOW61_21805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JOW61_21810	COG1847	R3H domain protein
JOW61_21815	COG0706	membrane insertase activity
JOW61_21820	COG0594	ribonuclease P activity
JOW61_21845	COG0629	single-stranded DNA binding
JOW61_21905	COG0791	NLP P60 protein
JOW61_21905	COG3883	PFAM NLP P60 protein
JOW61_22045	COG0457	Tetratricopeptide repeat
JOW61_22090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOW61_22195	COG1525	nuclease
JOW61_22210	COG1793	dna ligase