locus-tag	class	description
AWV81_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWV81_00010	COG0592	DNA-directed DNA polymerase activity
AWV81_00015	COG2501	S4 domain
AWV81_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWV81_00030	COG0187	DNA topoisomerase II activity
AWV81_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWV81_00070	COG0516	GMP reductase activity
AWV81_00070	COG0517	IMP dehydrogenase activity
AWV81_00075	COG1686	Belongs to the peptidase S11 family
AWV81_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AWV81_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AWV81_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWV81_00100	COG1428	Deoxynucleoside kinase
AWV81_00105	COG1428	Deoxynucleoside kinase
AWV81_00110	COG3858	chitin binding
AWV81_00110	COG1388	LysM domain
AWV81_00115	COG1335	isochorismatase
AWV81_00120	COG0590	tRNA wobble adenosine to inosine editing
AWV81_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWV81_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AWV81_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWV81_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AWV81_00190	COG3853	Toxic anion resistance protein (TelA)
AWV81_00195	COG1982	Orn Lys Arg decarboxylase major
AWV81_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWV81_00205	COG3870	Protein conserved in bacteria
AWV81_00210	COG1728	Protein conserved in bacteria
AWV81_00215	COG0470	DNA polymerase III
AWV81_00220	COG1774	PSP1 C-terminal conserved region
AWV81_00225	COG4467	Involved in initiation control of chromosome replication
AWV81_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AWV81_00235	COG2827	Endonuclease containing a URI domain
AWV81_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWV81_00245	COG2002	toxin-antitoxin pair type II binding
AWV81_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_00255	COG0084	hydrolase, TatD family'
AWV81_00260	COG3583	domain protein
AWV81_00260	COG3584	3D domain protein
AWV81_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWV81_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWV81_00280	COG4466	Protein conserved in bacteria
AWV81_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWV81_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWV81_00300	COG0251	oxidation-reduction process
AWV81_00305	COG2088	sporulation resulting in formation of a cellular spore
AWV81_00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWV81_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWV81_00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWV81_00330	COG0193	aminoacyl-tRNA hydrolase activity
AWV81_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWV81_00345	COG2002	toxin-antitoxin pair type II binding
AWV81_00350	COG2244	polysaccharide biosynthetic process
AWV81_00355	COG3956	TIGRFAM MazG family protein
AWV81_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWV81_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AWV81_00380	COG1098	S1 RNA binding domain
AWV81_00395	COG2208	phosphoserine phosphatase activity
AWV81_00400	COG2304	oxidoreductase activity
AWV81_00405	COG0515	serine threonine protein kinase
AWV81_00410	COG0037	tRNA processing
AWV81_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWV81_00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWV81_00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWV81_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWV81_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWV81_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWV81_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
AWV81_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWV81_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWV81_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWV81_00475	COG1396	sequence-specific DNA binding
AWV81_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWV81_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWV81_00565	COG4463	regulation of RNA biosynthetic process
AWV81_00570	COG3880	PFAM UvrB UvrC protein
AWV81_00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AWV81_00580	COG0542	response to heat
AWV81_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWV81_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AWV81_00595	COG4956	integral membrane protein (PIN domain superfamily)
AWV81_00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWV81_00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWV81_00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWV81_00620	COG1045	serine acetyltransferase
AWV81_00625	COG0215	cysteine-tRNA ligase activity
AWV81_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWV81_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWV81_00640	COG3688	RNA-binding protein containing a PIN domain
AWV81_00645	COG1595	DNA-templated transcription, initiation
AWV81_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWV81_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWV81_00660	COG0250	Participates in transcription elongation, termination and antitermination
AWV81_00665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWV81_00670	COG0081	regulation of translation
AWV81_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWV81_00680	COG0222	ribosome binding
AWV81_00685	COG2813	Specifically methylates the guanine in position
AWV81_00690	COG0085	RNA polymerase activity
AWV81_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWV81_00700	COG1358	cellular component organization or biogenesis
AWV81_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWV81_00710	COG0049	tRNA binding
AWV81_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWV81_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWV81_00725	COG0596	Alpha beta hydrolase
AWV81_00730	COG0051	transcription antitermination factor activity, RNA binding
AWV81_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWV81_00740	COG0088	Forms part of the polypeptide exit tunnel
AWV81_00745	COG0089	rRNA binding
AWV81_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWV81_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWV81_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AWV81_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWV81_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWV81_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
AWV81_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWV81_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWV81_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWV81_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWV81_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWV81_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWV81_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWV81_00825	COG1841	ribosomal large subunit assembly
AWV81_00830	COG0200	Binds to the 23S rRNA
AWV81_00835	COG0201	protein transport
AWV81_00840	COG0563	adenylate kinase activity
AWV81_00845	COG0024	Methionine aminopeptidase
AWV81_00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
AWV81_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AWV81_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AWV81_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWV81_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWV81_00875	COG0202	RNA polymerase activity
AWV81_00880	COG0203	ribosomal protein L17
AWV81_00885	COG1122	ATPase activity
AWV81_00890	COG1122	ATPase activity
AWV81_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWV81_00900	COG0101	tRNA pseudouridine synthase activity
AWV81_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWV81_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWV81_00915	COG2226	methyltransferase
AWV81_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_00930	COG0489	protein tyrosine kinase activity
AWV81_00940	COG2194	sulfuric ester hydrolase activity
AWV81_00945	COG0726	polysaccharide deacetylase
AWV81_01030	COG0659	secondary active sulfate transmembrane transporter activity
AWV81_01035	COG0385	Bile acid
AWV81_01040	COG2819	hydrolase of the alpha beta superfamily
AWV81_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_01060	COG2207	Transcriptional regulator
AWV81_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_01065	COG3876	Protein conserved in bacteria
AWV81_01070	COG1472	Belongs to the glycosyl hydrolase 3 family
AWV81_01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWV81_01080	COG1263	PTS System
AWV81_01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_01085	COG1737	Transcriptional regulator
AWV81_01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWV81_01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_01100	COG1683	Conserved Protein
AWV81_01130	COG1595	DNA-templated transcription, initiation
AWV81_01135	COG5662	AntiSigma factor
AWV81_01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWV81_01145	COG4856	YbbR-like protein
AWV81_01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWV81_01155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWV81_01165	COG2169	Transcriptional regulator
AWV81_01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWV81_01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWV81_01180	COG3002	Belongs to the UPF0753 family
AWV81_01185	COG0288	reversible hydration of carbon dioxide
AWV81_01195	COG5609	conserved protein (DUF2294)
AWV81_01205	COG0642	Histidine kinase
AWV81_01215	COG0515	serine threonine protein kinase
AWV81_01230	COG1113	amino acid transport
AWV81_01245	COG2602	Beta-lactamase
AWV81_01250	COG2124	cytochrome p450
AWV81_01260	COG0531	amino acid
AWV81_01265	COG0584	glycerophosphoryl diester phosphodiesterase
AWV81_01270	COG2271	Major facilitator Superfamily
AWV81_01280	COG1846	Transcriptional regulator
AWV81_01280	COG0456	acetyltransferase
AWV81_01300	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_01305	COG0697	spore germination
AWV81_01310	COG2207	Transcriptional regulator
AWV81_01310	COG1917	Cupin 2, conserved barrel domain protein
AWV81_01325	COG3179	chitinase
AWV81_01335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AWV81_01340	COG3591	Belongs to the peptidase S1B family
AWV81_01350	COG0596	Alpha beta hydrolase
AWV81_01355	COG1183	phosphatidylcholine synthase activity
AWV81_01360	COG0586	Pfam SNARE associated Golgi protein
AWV81_01365	COG0688	phosphatidylethanolamine metabolic process
AWV81_01375	COG2312	Erythromycin esterase
AWV81_01380	COG2207	Transcriptional regulator
AWV81_01390	COG1301	dicarboxylic acid transport
AWV81_01395	COG2190	(PTS) system
AWV81_01395	COG1263	PTS System
AWV81_01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_01400	COG0363	glucosamine-6-phosphate deaminase activity
AWV81_01415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_01420	COG0833	amino acid
AWV81_01425	COG2040	homocysteine
AWV81_01440	COG2066	Belongs to the glutaminase family
AWV81_01445	COG4191	Histidine kinase
AWV81_01450	COG0784	Response regulator, receiver
AWV81_01455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWV81_01460	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_01465	COG2271	Major facilitator Superfamily
AWV81_01470	COG4948	Mandelate Racemase Muconate Lactonizing
AWV81_01475	COG2186	Transcriptional regulator
AWV81_01480	COG2721	sulfolactate sulfo-lyase activity
AWV81_01485	COG3173	Aminoglycoside phosphotransferase
AWV81_01495	COG0697	spore germination
AWV81_01500	COG0745	RESPONSE REGULATOR receiver
AWV81_01505	COG2205	protein histidine kinase activity
AWV81_01510	COG1131	(ABC) transporter
AWV81_01530	COG3773	Cell wall hydrolase
AWV81_01535	COG2304	oxidoreductase activity
AWV81_01545	COG3540	Alkaline phosphatase
AWV81_01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWV81_01555	COG0805	protein transport
AWV81_01560	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWV81_01565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWV81_01570	COG0477	Major facilitator Superfamily
AWV81_01575	COG1309	transcriptional regulator
AWV81_01580	COG0252	asparaginase activity
AWV81_01585	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWV81_01590	COG1714	RDD family
AWV81_01595	COG3012	SEC-C Motif Domain Protein
AWV81_01595	COG1405	negative regulation of cell septum assembly
AWV81_01605	COG3279	Response regulator of the LytR AlgR family
AWV81_01615	COG1668	transmembrane transport
AWV81_01620	COG0667	Aldo Keto reductase
AWV81_01630	COG1595	DNA-templated transcription, initiation
AWV81_01635	COG1595	DNA-templated transcription, initiation
AWV81_01640	COG1876	peptidase activity
AWV81_01650	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_01655	COG0366	Alpha amylase catalytic
AWV81_01660	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWV81_01665	COG1121	(ABC) transporter
AWV81_01670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWV81_01680	COG2310	stress, protein
AWV81_01685	COG2310	stress, protein
AWV81_01690	COG2310	stress, protein
AWV81_01695	COG0861	Integral membrane protein TerC family
AWV81_01705	COG3853	Toxic anion resistance protein (TelA)
AWV81_01715	COG2801	Transposase and inactivated derivatives
AWV81_01720	COG0477	Major facilitator Superfamily
AWV81_01725	COG2814	Major facilitator Superfamily
AWV81_01730	COG0640	Transcriptional regulator
AWV81_01735	COG4175	Glycine betaine
AWV81_01735	COG0517	IMP dehydrogenase activity
AWV81_01740	COG4176	ABC-type proline glycine betaine transport system permease component
AWV81_01745	COG2113	Glycine betaine
AWV81_01750	COG1473	amidohydrolase
AWV81_01755	COG1288	antiporter activity
AWV81_01775	COG0039	L-malate dehydrogenase activity
AWV81_01785	COG3403	YqcI/YcgG family
AWV81_01800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWV81_01805	COG1660	Displays ATPase and GTPase activities
AWV81_01810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWV81_01825	COG2226	methyltransferase
AWV81_01830	COG0583	DNA-binding transcription factor activity
AWV81_01835	COG3458	cephalosporin-C deacetylase activity
AWV81_01840	COG3541	Predicted nucleotidyltransferase
AWV81_01845	COG0506	proline dehydrogenase activity
AWV81_01850	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_01855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_01860	COG2508	Transcriptional regulator
AWV81_01865	COG3689	TIGRFAM TIGR03943 family protein
AWV81_01870	COG0701	Predicted permease
AWV81_01875	COG2267	carboxylic ester hydrolase activity
AWV81_01880	COG0492	ferredoxin-NADP+ reductase activity
AWV81_01885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWV81_01885	COG1587	Uroporphyrinogen-III synthase
AWV81_01890	COG2146	nitrite reductase [NAD(P)H] activity
AWV81_01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWV81_01900	COG0243	molybdopterin cofactor binding
AWV81_01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWV81_01910	COG2223	nitrite transmembrane transporter activity
AWV81_01920	COG1376	ErfK ybiS ycfS ynhG family protein
AWV81_01935	COG0765	amino acid transport
AWV81_01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_01950	COG1714	RDD family
AWV81_01960	COG1846	Transcriptional regulator
AWV81_01975	COG2723	6-phospho-beta-galactosidase activity
AWV81_01985	COG3209	COG3209 Rhs family protein
AWV81_01995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AWV81_02000	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AWV81_02005	COG1733	regulation of RNA biosynthetic process
AWV81_02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_02030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AWV81_02035	COG2814	Major facilitator Superfamily
AWV81_02045	COG0697	spore germination
AWV81_02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_02060	COG2364	Membrane
AWV81_02065	COG1126	abc transporter atp-binding protein
AWV81_02070	COG0765	amino acid transport
AWV81_02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_02080	COG0583	DNA-binding transcription factor activity
AWV81_02085	COG0163	prenyltransferase activity
AWV81_02090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWV81_02105	COG0596	Alpha beta hydrolase
AWV81_02110	COG3104	oligopeptide transport
AWV81_02115	COG5434	Belongs to the glycosyl hydrolase 28 family
AWV81_02125	COG0697	spore germination
AWV81_02135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWV81_02140	COG1136	(ABC) transporter
AWV81_02145	COG0577	efflux transmembrane transporter activity
AWV81_02150	COG0745	RESPONSE REGULATOR receiver
AWV81_02155	COG3850	Histidine kinase
AWV81_02155	COG5002	protein histidine kinase activity
AWV81_02160	COG0457	Tetratricopeptide repeat
AWV81_02175	COG0527	aspartate kinase activity
AWV81_02180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_02185	COG4605	iron ion homeostasis
AWV81_02190	COG4604	ABC transporter, ATP-binding protein
AWV81_02195	COG4607	ABC-type enterochelin transport system periplasmic component
AWV81_02205	COG2814	Major facilitator Superfamily
AWV81_02210	COG1309	transcriptional regulator
AWV81_02215	COG0778	Nitroreductase
AWV81_02220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AWV81_02225	COG0640	Transcriptional regulator
AWV81_02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_02235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AWV81_02240	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_02245	COG4975	Glucose uptake
AWV81_02250	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_02255	COG4549	nuclear export factor GLE1
AWV81_02260	COG2372	response to copper ion
AWV81_02260	COG1276	copper resistance
AWV81_02265	COG1349	DNA-binding transcription factor activity
AWV81_02275	COG2213	PTS system mannitol-specific
AWV81_02280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_02285	COG0246	Mannitol dehydrogenase
AWV81_02290	COG0473	3-isopropylmalate dehydrogenase activity
AWV81_02295	COG0681	Belongs to the peptidase S26 family
AWV81_02305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWV81_02315	COG0561	phosphatase activity
AWV81_02320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AWV81_02325	COG1914	H( )-stimulated, divalent metal cation uptake system
AWV81_02330	COG4336	lyase activity
AWV81_02335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AWV81_02340	COG1984	allophanate hydrolase subunit 2
AWV81_02345	COG1414	Transcriptional regulator
AWV81_02350	COG2755	lipolytic protein G-D-S-L family
AWV81_02360	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_02365	COG0768	penicillin binding
AWV81_02370	COG4989	oxidoreductase activity
AWV81_02375	COG3711	transcriptional antiterminator
AWV81_02380	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_02385	COG2226	methyltransferase
AWV81_02390	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_02395	COG1917	Cupin 2, conserved barrel domain protein
AWV81_02400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_02405	COG3871	stress protein (general stress protein 26)
AWV81_02415	COG2814	Major facilitator Superfamily
AWV81_02420	COG1522	sequence-specific DNA binding
AWV81_02425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWV81_02425	COG0551	DNA topoisomerase type I activity
AWV81_02430	COG0494	nUDIX hydrolase
AWV81_02435	COG0028	Belongs to the TPP enzyme family
AWV81_02465	COG1914	H( )-stimulated, divalent metal cation uptake system
AWV81_02470	COG2261	transglycosylase associated protein
AWV81_02475	COG4876	unkown
AWV81_02480	COG2217	Heavy metal translocating P-type atpase
AWV81_02485	COG3729	General stress protein
AWV81_02490	COG0662	Cupin 2, conserved barrel domain protein
AWV81_02495	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_02500	COG3546	catalase activity
AWV81_02505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AWV81_02510	COG3290	protein histidine kinase activity
AWV81_02515	COG4565	transcriptional regulatory protein
AWV81_02520	COG1301	dicarboxylic acid transport
AWV81_02525	COG0628	permease
AWV81_02535	COG1131	(ABC) transporter
AWV81_02540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWV81_02550	COG1960	acyl-CoA dehydrogenase activity
AWV81_02565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWV81_02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_02575	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWV81_02580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWV81_02585	COG0513	Belongs to the DEAD box helicase family
AWV81_02590	COG3402	PFAM membrane-flanked domain
AWV81_02595	COG3428	Bacterial PH domain
AWV81_02600	COG0705	Rhomboid family
AWV81_02605	COG0736	holo-[acyl-carrier-protein] synthase activity
AWV81_02610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AWV81_02615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWV81_02620	COG0864	Transcriptional regulator
AWV81_02625	COG2337	Toxic component of a toxin-antitoxin (TA) module
AWV81_02630	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_02635	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_02640	COG2172	sigma factor antagonist activity
AWV81_02645	COG2208	phosphoserine phosphatase activity
AWV81_02650	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_02655	COG2172	sigma factor antagonist activity
AWV81_02660	COG1191	sigma factor activity
AWV81_02665	COG2208	phosphoserine phosphatase activity
AWV81_02680	COG1673	EVE domain
AWV81_02685	COG1846	Transcriptional regulator
AWV81_02690	COG2183	response to ionizing radiation
AWV81_02700	COG3091	SprT-like family
AWV81_02740	COG0582	viral genome integration into host DNA
AWV81_02745	COG2856	Zn peptidase
AWV81_02750	COG1396	sequence-specific DNA binding
AWV81_02775	COG1674	ftsk spoiiie
AWV81_02780	COG2946	Replication initiation factor
AWV81_02820	COG0433	COG0433 Predicted ATPase
AWV81_02830	COG5644	endopeptidase inhibitor activity
AWV81_02840	COG0791	NLP P60 protein
AWV81_02840	COG0741	lytic transglycosylase activity
AWV81_02855	COG0457	Tetratricopeptide repeat
AWV81_02885	COG0583	DNA-binding transcription factor activity
AWV81_02890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_02900	COG5444	nuclease activity
AWV81_02905	COG1476	TRANSCRIPTIONal
AWV81_02930	COG0693	protein deglycase activity
AWV81_02935	COG1278	Cold shock
AWV81_02940	COG1329	Transcriptional regulator
AWV81_02945	COG0697	spore germination
AWV81_02950	COG1917	Cupin 2, conserved barrel domain protein
AWV81_02950	COG2207	Transcriptional regulator
AWV81_02960	COG3708	Transcriptional regulator
AWV81_02960	COG2207	Transcriptional regulator
AWV81_02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_02980	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AWV81_02995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_03000	COG1309	transcriptional regulator
AWV81_03005	COG0697	spore germination
AWV81_03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_03015	COG2030	dehydratase
AWV81_03020	COG3545	Serine hydrolase
AWV81_03030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_03035	COG0640	Transcriptional regulator
AWV81_03040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWV81_03050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_03055	COG0697	spore germination
AWV81_03060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_03065	COG0076	glutamate decarboxylase activity
AWV81_03070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWV81_03075	COG0640	Transcriptional regulator
AWV81_03080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AWV81_03090	COG4585	Histidine kinase
AWV81_03095	COG2197	response regulator
AWV81_03100	COG2409	Drug exporters of the RND superfamily
AWV81_03105	COG0596	Alpha beta hydrolase
AWV81_03110	COG1811	Na channel or pump
AWV81_03115	COG4978	Transcriptional regulator
AWV81_03115	COG0789	Transcriptional regulator
AWV81_03120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWV81_03125	COG0778	Nitroreductase
AWV81_03130	COG0346	lactoylglutathione lyase activity
AWV81_03135	COG2259	Doxx family
AWV81_03140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_03170	COG2323	membrane
AWV81_03175	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_03190	COG1309	transcriptional regulator
AWV81_03200	COG0456	acetyltransferase
AWV81_03210	COG1113	amino acid transport
AWV81_03215	COG2318	DinB family
AWV81_03220	COG1846	Transcriptional regulator
AWV81_03225	COG1033	growth of symbiont in host cell
AWV81_03225	COG2409	Drug exporters of the RND superfamily
AWV81_03230	COG0778	Nitroreductase
AWV81_03235	COG1846	Transcriptional regulator
AWV81_03240	COG2814	Major facilitator Superfamily
AWV81_03245	COG0730	response to heat
AWV81_03250	COG1802	Transcriptional regulator
AWV81_03255	COG1388	LysM domain
AWV81_03255	COG3858	chitin binding
AWV81_03260	COG1819	glycosyl
AWV81_03270	COG1785	Belongs to the alkaline phosphatase family
AWV81_03275	COG5646	InterPro IPR014922
AWV81_03285	COG0454	-acetyltransferase
AWV81_03290	COG1078	dGTPase activity
AWV81_03295	COG1388	LysM domain
AWV81_03300	COG2814	Major facilitator Superfamily
AWV81_03305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_03320	COG2723	6-phospho-beta-galactosidase activity
AWV81_03325	COG2188	Transcriptional regulator
AWV81_03330	COG1940	carbohydrate kinase activity
AWV81_03340	COG4124	Belongs to the glycosyl hydrolase 26 family
AWV81_03385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWV81_03390	COG0802	atpase or kinase
AWV81_03395	COG1214	PFAM Peptidase M22, glycoprotease
AWV81_03400	COG0456	acetyltransferase
AWV81_03405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWV81_03410	COG0488	(ABC) transporter
AWV81_03415	COG0315	cyclic pyranopterin monophosphate synthase activity
AWV81_03420	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AWV81_03425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWV81_03430	COG0805	protein transport
AWV81_03440	COG1266	CAAX protease self-immunity
AWV81_03445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWV81_03450	COG0459	protein refolding
AWV81_03465	COG0457	Tetratricopeptide repeat
AWV81_03470	COG1063	alcohol dehydrogenase
AWV81_03475	COG2211	Major facilitator Superfamily
AWV81_03480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_03490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWV81_03495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AWV81_03500	COG4260	virion core protein, lumpy skin disease virus
AWV81_03510	COG2814	Major facilitator Superfamily
AWV81_03515	COG1063	alcohol dehydrogenase
AWV81_03520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWV81_03525	COG0823	Involved in the tonB-independent uptake of proteins
AWV81_03530	COG2801	Transposase and inactivated derivatives
AWV81_03550	COG2267	carboxylic ester hydrolase activity
AWV81_03560	COG2132	Multicopper oxidase
AWV81_03565	COG1113	amino acid transport
AWV81_03575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWV81_03580	COG0714	Associated with various cellular activities
AWV81_03585	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AWV81_03590	COG1305	Transglutaminase-like
AWV81_03595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWV81_03595	COG0519	Catalyzes the synthesis of GMP from XMP
AWV81_03605	COG2252	PERMEase
AWV81_03610	COG3064	Membrane
AWV81_03620	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AWV81_03630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWV81_03635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWV81_03640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWV81_03645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWV81_03650	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWV81_03655	COG0047	phosphoribosylformylglycinamidine synthase activity
AWV81_03660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWV81_03665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWV81_03670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWV81_03675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWV81_03680	COG0138	bifunctional purine biosynthesis protein purh
AWV81_03685	COG0151	Belongs to the GarS family
AWV81_03690	COG1522	sequence-specific DNA binding
AWV81_03695	COG0531	amino acid
AWV81_03705	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AWV81_03710	COG1470	cell adhesion involved in biofilm formation
AWV81_03715	COG4496	protein, YerC YecD
AWV81_03720	COG0069	glutamate synthase activity
AWV81_03730	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AWV81_03735	COG0210	DNA helicase
AWV81_03740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWV81_03745	COG4851	CamS sex pheromone cAM373 precursor
AWV81_03755	COG2801	Transposase and inactivated derivatives
AWV81_03760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_03765	COG1285	pathogenesis
AWV81_03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_03775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWV81_03780	COG0154	amidase activity
AWV81_03785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWV81_03790	COG1309	transcriptional regulator
AWV81_03795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AWV81_03800	COG1597	lipid kinase activity
AWV81_03805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWV81_03830	COG5444	nuclease activity
AWV81_03840	COG0457	Tetratricopeptide repeat
AWV81_03850	COG0217	transcriptional regulatory protein
AWV81_03860	COG1309	transcriptional regulator
AWV81_03875	COG3546	catalase activity
AWV81_03880	COG0454	-acetyltransferase
AWV81_03890	COG5578	integral membrane protein
AWV81_03895	COG2972	Histidine kinase
AWV81_03905	COG1653	transport
AWV81_03910	COG1175	transmembrane transport
AWV81_03915	COG0395	ABC-type sugar transport system, permease component
AWV81_03920	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWV81_03925	COG2207	Transcriptional regulator
AWV81_03930	COG2755	lipolytic protein G-D-S-L family
AWV81_03940	COG5578	integral membrane protein
AWV81_03945	COG3401	FG-GAP repeat protein
AWV81_03950	COG3401	FG-GAP repeat protein
AWV81_03955	COG2755	lipolytic protein G-D-S-L family
AWV81_03970	COG1653	transport
AWV81_03975	COG4209	transmembrane transport
AWV81_03980	COG0395	ABC-type sugar transport system, permease component
AWV81_03985	COG1486	melibiose metabolic process
AWV81_03990	COG2323	membrane
AWV81_03995	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_04000	COG0346	lactoylglutathione lyase activity
AWV81_04015	COG5583	Uncharacterized small protein (DUF2292)
AWV81_04020	COG0670	Belongs to the BI1 family
AWV81_04025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWV81_04035	COG3328	transposase activity
AWV81_04045	COG2124	cytochrome p450
AWV81_04045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWV81_04050	COG1368	sulfuric ester hydrolase activity
AWV81_04055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWV81_04060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWV81_04065	COG1442	glycosyl transferase family 8
AWV81_04070	COG1216	Glycosyl transferase, family 2
AWV81_04075	COG1442	glycosyl transferase family 8
AWV81_04080	COG2223	nitrite transmembrane transporter activity
AWV81_04085	COG1011	Hydrolase
AWV81_04090	COG0531	amino acid
AWV81_04095	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_04100	COG0840	transmembrane signaling receptor activity
AWV81_04105	COG0488	(ABC) transporter
AWV81_04115	COG0789	Transcriptional regulator
AWV81_04120	COG2814	Major facilitator Superfamily
AWV81_04135	COG2801	Transposase and inactivated derivatives
AWV81_04140	COG0488	(ABC) transporter
AWV81_04145	COG0513	Belongs to the DEAD box helicase family
AWV81_04155	COG3866	Pectate lyase
AWV81_04160	COG0471	metal ion transport
AWV81_04165	COG3290	protein histidine kinase activity
AWV81_04170	COG4565	transcriptional regulatory protein
AWV81_04175	COG3181	Tripartite tricarboxylate transporter family receptor
AWV81_04185	COG2851	Citrate transporter
AWV81_04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_04195	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AWV81_04200	COG1254	Belongs to the acylphosphatase family
AWV81_04205	COG2258	MOSC domain
AWV81_04225	COG0024	Methionine aminopeptidase
AWV81_04230	COG1263	PTS System
AWV81_04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_04235	COG1368	sulfuric ester hydrolase activity
AWV81_04245	COG1115	amino acid carrier protein
AWV81_04250	COG0531	amino acid
AWV81_04255	COG0697	spore germination
AWV81_04260	COG1263	PTS System
AWV81_04260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_04265	COG0366	Alpha amylase catalytic
AWV81_04270	COG2188	Transcriptional regulator
AWV81_04275	COG0778	Nitroreductase
AWV81_04280	COG0737	Belongs to the 5'-nucleotidase family
AWV81_04285	COG0693	protein deglycase activity
AWV81_04295	COG2801	Transposase and inactivated derivatives
AWV81_04300	COG2814	Major facilitator Superfamily
AWV81_04305	COG4840	Belongs to the UPF0435 family
AWV81_04310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWV81_04315	COG4980	gas vesicle protein
AWV81_04320	COG1295	ribonuclease BN
AWV81_04330	COG0477	Major facilitator Superfamily
AWV81_04340	COG0387	Pfam Sodium calcium exchanger
AWV81_04350	COG0668	transmembrane transport
AWV81_04355	COG0535	radical SAM domain protein
AWV81_04365	COG0726	polysaccharide deacetylase
AWV81_04370	COG2084	Dehydrogenase
AWV81_04375	COG0598	Magnesium transport protein CorA
AWV81_04380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AWV81_04385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWV81_04395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWV81_04400	COG4637	Psort location Cytoplasmic, score
AWV81_04410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWV81_04415	COG0022	dehydrogenase e1 component
AWV81_04420	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_04425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWV81_04430	COG3284	Transcriptional regulator
AWV81_04440	COG1742	UPF0060 membrane protein
AWV81_04465	COG4842	Belongs to the WXG100 family
AWV81_04470	COG1486	melibiose metabolic process
AWV81_04475	COG1737	Transcriptional regulator
AWV81_04480	COG1263	PTS System
AWV81_04480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_04485	COG5434	Belongs to the glycosyl hydrolase 28 family
AWV81_04490	COG1132	(ABC) transporter
AWV81_04495	COG1132	(ABC) transporter
AWV81_04500	COG2259	Doxx family
AWV81_04505	COG2514	catechol 2,3-dioxygenase activity
AWV81_04510	COG4977	sequence-specific DNA binding
AWV81_04510	COG1917	Cupin 2, conserved barrel domain protein
AWV81_04515	COG2814	Major facilitator Superfamily
AWV81_04520	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_04530	COG4585	Histidine kinase
AWV81_04535	COG2197	response regulator
AWV81_04540	COG1131	(ABC) transporter
AWV81_04545	COG1511	domain protein
AWV81_04545	COG0842	Transport permease protein
AWV81_04550	COG0842	Transport permease protein
AWV81_04555	COG1695	Transcriptional regulator
AWV81_04560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWV81_04565	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AWV81_04570	COG1309	transcriptional regulator
AWV81_04575	COG2814	Major facilitator Superfamily
AWV81_04580	COG2318	DinB family
AWV81_04590	COG1846	Transcriptional regulator
AWV81_04595	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AWV81_04595	COG0392	lysyltransferase activity
AWV81_04600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_04605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_04610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_04615	COG0384	phenazine biosynthesis protein PhzF
AWV81_04620	COG0778	Nitroreductase
AWV81_04635	COG1090	epimerase
AWV81_04640	COG2137	regulation of response to DNA damage stimulus
AWV81_04655	COG2814	Major facilitator Superfamily
AWV81_04670	COG3103	Sh3 type 3 domain protein
AWV81_04675	COG5658	integral membrane protein
AWV81_04680	COG0596	Alpha beta hydrolase
AWV81_04685	COG0463	Glycosyl transferase, family 2
AWV81_04690	COG4485	Bacterial membrane protein, YfhO
AWV81_04695	COG1988	membrane-bound metal-dependent
AWV81_04700	COG1194	a g-specific adenine glycosylase
AWV81_04710	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_04725	COG3557	Belongs to the UPF0374 family
AWV81_04730	COG1132	(ABC) transporter
AWV81_04735	COG4129	membrane
AWV81_04740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWV81_04745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWV81_04750	COG0735	belongs to the Fur family
AWV81_04865	COG4326	sporulation control protein
AWV81_04875	COG5577	PFAM Coat F domain
AWV81_04880	COG3340	Belongs to the peptidase S51 family
AWV81_04885	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWV81_04900	COG0753	catalase activity
AWV81_04905	COG1116	anion transmembrane transporter activity
AWV81_04910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWV81_04915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWV81_04920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWV81_04930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWV81_04940	COG1476	TRANSCRIPTIONal
AWV81_04950	COG3382	B3 4 domain protein
AWV81_04955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWV81_04965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWV81_04970	COG0789	Transcriptional regulator
AWV81_04975	COG1664	Polymer-forming cytoskeletal
AWV81_04980	COG1664	Polymer-forming cytoskeletal
AWV81_04985	COG2766	serine protein kinase
AWV81_04990	COG2718	Belongs to the UPF0229 family
AWV81_05000	COG1846	Transcriptional regulator
AWV81_05005	COG1566	PFAM secretion protein HlyD family protein
AWV81_05010	COG2814	Major facilitator Superfamily
AWV81_05015	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWV81_05030	COG1725	Transcriptional regulator
AWV81_05035	COG1131	(ABC) transporter
AWV81_05040	COG1131	(ABC) transporter
AWV81_05045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWV81_05050	COG1278	Cold shock
AWV81_05055	COG1464	Belongs to the NlpA lipoprotein family
AWV81_05060	COG3706	GGDEF domain
AWV81_05065	COG1823	symporter activity
AWV81_05070	COG5444	nuclease activity
AWV81_05095	COG0582	viral genome integration into host DNA
AWV81_05145	COG5644	endopeptidase inhibitor activity
AWV81_05150	COG0791	NLP P60 protein
AWV81_05150	COG0741	lytic transglycosylase activity
AWV81_05170	COG0457	Tetratricopeptide repeat
AWV81_05190	COG5577	PFAM Coat F domain
AWV81_05195	COG1525	nuclease
AWV81_05195	COG4085	toxin activity
AWV81_05195	COG0737	Belongs to the 5'-nucleotidase family
AWV81_05200	COG3764	Sortase (surface protein transpeptidase)
AWV81_05205	COG0564	pseudouridine synthase activity
AWV81_05215	COG0517	IMP dehydrogenase activity
AWV81_05220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWV81_05225	COG3153	acetyltransferase
AWV81_05225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWV81_05230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWV81_05235	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AWV81_05240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWV81_05245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWV81_05250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWV81_05255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWV81_05260	COG4585	Histidine kinase
AWV81_05260	COG2203	Gaf domain
AWV81_05265	COG2197	response regulator
AWV81_05270	COG0431	NADPH-dependent FMN reductase
AWV81_05285	COG0791	NLP P60 protein
AWV81_05285	COG1388	LysM domain
AWV81_05290	COG1959	2 iron, 2 sulfur cluster binding
AWV81_05295	COG0668	transmembrane transport
AWV81_05300	COG2719	SpoVR family
AWV81_05305	COG1785	Belongs to the alkaline phosphatase family
AWV81_05310	COG1388	LysM domain
AWV81_05310	COG0791	NLP P60 protein
AWV81_05315	COG0583	DNA-binding transcription factor activity
AWV81_05320	COG0372	Belongs to the citrate synthase family
AWV81_05325	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_05330	COG0531	amino acid
AWV81_05335	COG0733	neurotransmitter:sodium symporter activity
AWV81_05340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_05345	COG0456	acetyltransferase
AWV81_05360	COG1595	DNA-templated transcription, initiation
AWV81_05365	COG0667	Aldo Keto reductase
AWV81_05370	COG0204	Acyl-transferase
AWV81_05375	COG1253	flavin adenine dinucleotide binding
AWV81_05380	COG0789	Transcriptional regulator
AWV81_05390	COG1253	flavin adenine dinucleotide binding
AWV81_05395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWV81_05400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWV81_05405	COG0584	glycerophosphoryl diester phosphodiesterase
AWV81_05415	COG0668	transmembrane transport
AWV81_05420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWV81_05425	COG0726	polysaccharide deacetylase
AWV81_05430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_05435	COG1757	Na H antiporter
AWV81_05440	COG0589	response to stress
AWV81_05450	COG1132	(ABC) transporter
AWV81_05455	COG1132	(ABC) transporter
AWV81_05460	COG0702	epimerase
AWV81_05480	COG0189	ligase activity
AWV81_05485	COG0189	ligase activity
AWV81_05490	COG4399	Belongs to the UPF0754 family
AWV81_05495	COG3679	Belongs to the UPF0342 family
AWV81_05505	COG0561	phosphatase activity
AWV81_05510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWV81_05515	COG0475	glutathione-regulated potassium exporter activity
AWV81_05520	COG0490	domain, Protein
AWV81_05530	COG1024	Enoyl-CoA hydratase
AWV81_05540	COG4152	abc transporter atp-binding protein
AWV81_05545	COG1668	transmembrane transport
AWV81_05550	COG0420	3'-5' exonuclease activity
AWV81_05555	COG4717	serine-type aminopeptidase activity
AWV81_05560	COG3481	metal-dependent phosphohydrolase, HD sub domain
AWV81_05570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWV81_05590	COG1846	Transcriptional regulator
AWV81_05595	COG4980	gas vesicle protein
AWV81_05610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AWV81_05615	COG0537	adenosine 5'-monophosphoramidase activity
AWV81_05620	COG1131	(ABC) transporter
AWV81_05625	COG4473	ABC transporter
AWV81_05635	COG1473	amidohydrolase
AWV81_05640	COG3069	C4-dicarboxylate transmembrane transporter activity
AWV81_05650	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_05655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_05660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWV81_05675	COG1309	transcriptional regulator
AWV81_05680	COG1511	domain protein
AWV81_05685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWV81_05690	COG4377	Putative membrane peptidase family (DUF2324)
AWV81_05700	COG1363	Peptidase, m42
AWV81_05705	COG4405	Protein conserved in bacteria
AWV81_05710	COG1301	dicarboxylic acid transport
AWV81_05720	COG1234	tRNA 3'-trailer cleavage
AWV81_05725	COG0095	Lipoate-protein ligase
AWV81_05730	COG0702	epimerase
AWV81_05735	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_05745	COG0501	Belongs to the peptidase M48B family
AWV81_05755	COG0456	acetyltransferase
AWV81_05760	COG0604	alcohol dehydrogenase
AWV81_05765	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AWV81_05770	COG0406	alpha-ribazole phosphatase activity
AWV81_05775	COG0183	Belongs to the thiolase family
AWV81_05780	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_05785	COG1268	BioY protein
AWV81_05790	COG0840	transmembrane signaling receptor activity
AWV81_05800	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_05810	COG4903	ComK protein
AWV81_05815	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_05825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_05840	COG0398	Pfam SNARE associated Golgi protein
AWV81_05845	COG0681	Belongs to the peptidase S26 family
AWV81_05850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWV81_05855	COG1846	Transcriptional regulator
AWV81_05875	COG0738	Major facilitator superfamily
AWV81_05880	COG0673	inositol 2-dehydrogenase activity
AWV81_05885	COG0561	phosphatase activity
AWV81_05890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWV81_05895	COG1609	Transcriptional regulator
AWV81_05900	COG3180	Ammonia monooxygenase
AWV81_05905	COG0477	Major facilitator Superfamily
AWV81_05905	COG2814	Major facilitator Superfamily
AWV81_05910	COG4533	DNA binding
AWV81_05925	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWV81_05930	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AWV81_05935	COG1074	ATP-dependent DNA helicase activity
AWV81_05940	COG0420	3'-5' exonuclease activity
AWV81_05945	COG0419	ATPase involved in DNA repair
AWV81_05950	COG1403	HNH endonuclease
AWV81_05995	COG5337	Spore coat protein CotH
AWV81_06000	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWV81_06010	COG1404	Belongs to the peptidase S8 family
AWV81_06020	COG0367	asparagine synthase
AWV81_06025	COG1562	ergosterol biosynthetic process
AWV81_06030	COG0534	Mate efflux family protein
AWV81_06035	COG1917	Cupin 2, conserved barrel domain protein
AWV81_06035	COG2207	Transcriptional regulator
AWV81_06040	COG1609	Transcriptional regulator
AWV81_06045	COG0673	inositol 2-dehydrogenase activity
AWV81_06050	COG2318	DinB family
AWV81_06055	COG1279	arginine transmembrane transporter activity
AWV81_06060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWV81_06065	COG1357	PFAM Pentapeptide repeats (8 copies)
AWV81_06070	COG2267	carboxylic ester hydrolase activity
AWV81_06080	COG2153	protein acetylation
AWV81_06085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWV81_06085	COG0646	methionine synthase
AWV81_06090	COG1666	GTP binding
AWV81_06095	COG2996	Protein conserved in bacteria
AWV81_06105	COG1307	EDD domain protein, DegV family
AWV81_06110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_06130	COG0561	phosphatase activity
AWV81_06135	COG1073	alpha beta
AWV81_06140	COG2151	metal-sulfur cluster biosynthetic enzyme
AWV81_06160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWV81_06175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWV81_06180	COG0505	Belongs to the CarA family
AWV81_06185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWV81_06190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWV81_06195	COG2801	Transposase and inactivated derivatives
AWV81_06215	COG2267	carboxylic ester hydrolase activity
AWV81_06225	COG1744	ABC transporter substrate-binding protein PnrA-like
AWV81_06240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWV81_06245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWV81_06250	COG5504	Zn-dependent protease
AWV81_06255	COG0444	Belongs to the ABC transporter superfamily
AWV81_06260	COG4608	Belongs to the ABC transporter superfamily
AWV81_06270	COG0601	transmembrane transport
AWV81_06275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWV81_06285	COG0180	Tryptophanyl-tRNA synthetase
AWV81_06290	COG4166	transmembrane transport
AWV81_06295	COG0601	transmembrane transport
AWV81_06300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWV81_06305	COG0444	Belongs to the ABC transporter superfamily
AWV81_06310	COG4608	Belongs to the ABC transporter superfamily
AWV81_06315	COG2814	Major facilitator Superfamily
AWV81_06320	COG0456	acetyltransferase
AWV81_06325	COG1393	Belongs to the ArsC family
AWV81_06330	COG0861	Integral membrane protein TerC family
AWV81_06335	COG4862	establishment of competence for transformation
AWV81_06340	COG4469	Competence protein
AWV81_06345	COG1164	Oligoendopeptidase f
AWV81_06365	COG2346	COG2346, Truncated hemoglobins
AWV81_06370	COG0741	lytic transglycosylase activity
AWV81_06375	COG4116	CYTH
AWV81_06385	COG2357	RelA SpoT domain protein
AWV81_06390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWV81_06395	COG0564	pseudouridine synthase activity
AWV81_06400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWV81_06405	COG0569	domain protein
AWV81_06405	COG0475	glutathione-regulated potassium exporter activity
AWV81_06410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AWV81_06415	COG0352	thiamine-phosphate diphosphorylase activity
AWV81_06420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWV81_06425	COG2104	thiamine diphosphate biosynthetic process
AWV81_06430	COG2022	thiamine diphosphate biosynthetic process
AWV81_06435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_06440	COG0351	phosphomethylpyrimidine kinase
AWV81_06445	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AWV81_06505	COG0210	DNA helicase
AWV81_06515	COG2153	protein acetylation
AWV81_06520	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWV81_06525	COG2382	esterase
AWV81_06530	COG0626	cystathionine gamma-synthase activity
AWV81_06535	COG0626	cystathionine gamma-synthase activity
AWV81_06540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_06545	COG5505	Protein of unknown function (DUF819)
AWV81_06575	COG1396	sequence-specific DNA binding
AWV81_06645	COG0457	Tetratricopeptide repeat
AWV81_06650	COG5444	nuclease activity
AWV81_06660	COG3328	transposase activity
AWV81_06715	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AWV81_06725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_06725	COG3711	transcriptional antiterminator
AWV81_06730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_06730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_06730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_06735	COG1482	cell wall glycoprotein biosynthetic process
AWV81_06750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_06760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AWV81_06775	COG0109	protoheme IX farnesyltransferase activity
AWV81_06785	COG0726	polysaccharide deacetylase
AWV81_06805	COG5504	Zn-dependent protease
AWV81_06810	COG2205	protein histidine kinase activity
AWV81_06825	COG2427	Protein of unknown function (DUF1641)
AWV81_06835	COG1051	belongs to the nudix hydrolase family
AWV81_06845	COG2124	cytochrome p450
AWV81_06850	COG1819	glycosyl
AWV81_06860	COG1587	Uroporphyrinogen-III synthase
AWV81_06865	COG0390	transport system, permease component
AWV81_06870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWV81_06875	COG0697	spore germination
AWV81_06890	COG1252	NADH dehydrogenase
AWV81_06895	COG1904	glucuronate isomerase
AWV81_06900	COG2211	Major facilitator Superfamily
AWV81_06905	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AWV81_06910	COG1063	alcohol dehydrogenase
AWV81_06915	COG1312	Catalyzes the dehydration of D-mannonate
AWV81_06920	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_06925	COG2271	Major facilitator Superfamily
AWV81_06930	COG1609	Transcriptional regulator
AWV81_06935	COG0246	Mannitol dehydrogenase
AWV81_06940	COG2721	sulfolactate sulfo-lyase activity
AWV81_06945	COG0730	response to heat
AWV81_06950	COG2318	DinB family
AWV81_06960	COG2801	Transposase and inactivated derivatives
AWV81_06970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWV81_06975	COG0457	Tetratricopeptide repeat
AWV81_06990	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_06990	COG1388	LysM domain
AWV81_06990	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_07000	COG4195	phage-related replication protein
AWV81_07005	COG3546	catalase activity
AWV81_07010	COG2856	Zn peptidase
AWV81_07015	COG1396	sequence-specific DNA binding
AWV81_07025	COG1522	sequence-specific DNA binding
AWV81_07030	COG1484	DNA-dependent DNA replication
AWV81_07055	COG1595	DNA-templated transcription, initiation
AWV81_07060	COG3728	DNA packaging
AWV81_07060	COG5484	DNA packaging
AWV81_07065	COG1783	phage Terminase large subunit
AWV81_07070	COG5518	Phage portal protein
AWV81_07075	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWV81_07080	COG4653	Phage capsid family
AWV81_07135	COG1652	LysM domain
AWV81_07140	COG4193	domain, Protein
AWV81_07150	COG3628	GPW Gp25 family protein
AWV81_07155	COG3299	homolog of phage Mu protein gp47
AWV81_07160	COG3778	Protein conserved in bacteria
AWV81_07200	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_07200	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_07215	COG0306	phosphate transporter
AWV81_07220	COG1392	Phosphate transport regulator
AWV81_07225	COG0531	amino acid
AWV81_07230	COG0346	lactoylglutathione lyase activity
AWV81_07235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWV81_07240	COG0463	Glycosyl transferase, family 2
AWV81_07250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_07255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_07260	COG2362	D-Aminopeptidase
AWV81_07265	COG0601	transmembrane transport
AWV81_07270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWV81_07275	COG0444	Belongs to the ABC transporter superfamily
AWV81_07280	COG4166	transmembrane transport
AWV81_07285	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWV81_07290	COG4948	Mandelate Racemase Muconate Lactonizing
AWV81_07295	COG0791	NLP P60 protein
AWV81_07300	COG4608	Belongs to the ABC transporter superfamily
AWV81_07305	COG2706	6-phosphogluconolactonase activity
AWV81_07315	COG1607	acyl-coa hydrolase
AWV81_07320	COG1017	nitric oxide dioxygenase activity
AWV81_07320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWV81_07330	COG2323	membrane
AWV81_07335	COG2318	DinB family
AWV81_07340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_07345	COG2076	Multidrug Resistance protein
AWV81_07350	COG2076	Multidrug Resistance protein
AWV81_07355	COG0788	formyltetrahydrofolate deformylase activity
AWV81_07360	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWV81_07365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWV81_07370	COG1764	response to oxidative stress
AWV81_07375	COG1846	Transcriptional regulator
AWV81_07380	COG1764	response to oxidative stress
AWV81_07390	COG0590	tRNA wobble adenosine to inosine editing
AWV81_07395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWV81_07400	COG1404	Belongs to the peptidase S8 family
AWV81_07405	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_07410	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWV81_07415	COG1122	ATPase activity
AWV81_07420	COG4721	ABC-type cobalt transport system, permease component
AWV81_07430	COG0745	RESPONSE REGULATOR receiver
AWV81_07435	COG5002	protein histidine kinase activity
AWV81_07435	COG3850	Histidine kinase
AWV81_07440	COG3212	peptidase
AWV81_07445	COG3212	peptidase
AWV81_07465	COG2239	Acts as a magnesium transporter
AWV81_07470	COG0789	Transcriptional regulator
AWV81_07485	COG1846	Transcriptional regulator
AWV81_07490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWV81_07495	COG0726	polysaccharide deacetylase
AWV81_07500	COG1408	metallophosphoesterase
AWV81_07510	COG0463	Glycosyl transferase, family 2
AWV81_07515	COG3285	dna ligase
AWV81_07515	COG1793	dna ligase
AWV81_07520	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AWV81_07525	COG5001	Diguanylate cyclase
AWV81_07525	COG3300	MHYT domain
AWV81_07530	COG0586	Pfam SNARE associated Golgi protein
AWV81_07535	COG0861	Integral membrane protein TerC family
AWV81_07540	COG1191	sigma factor activity
AWV81_07560	COG0501	Belongs to the peptidase M48B family
AWV81_07565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWV81_07590	COG3594	Acyltransferase
AWV81_07595	COG5002	protein histidine kinase activity
AWV81_07600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AWV81_07610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWV81_07615	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AWV81_07620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWV81_07625	COG0436	Aminotransferase
AWV81_07630	COG1850	ribulose-bisphosphate carboxylase activity
AWV81_07635	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AWV81_07640	COG0235	Class ii aldolase
AWV81_07645	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWV81_07650	COG3339	Conserved Protein
AWV81_07665	COG3852	Histidine kinase
AWV81_07670	COG1846	Transcriptional regulator
AWV81_07675	COG1360	Flagellar Motor Protein
AWV81_07680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AWV81_07685	COG0542	response to heat
AWV81_07690	COG3949	Membrane
AWV81_07695	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWV81_07700	COG0720	synthase
AWV81_07705	COG0602	queuosine metabolic process
AWV81_07710	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWV81_07720	COG4873	Protein conserved in bacteria
AWV81_07735	COG3773	Cell wall hydrolase
AWV81_07740	COG2244	polysaccharide biosynthetic process
AWV81_07745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_07750	COG2217	Heavy metal translocating P-type atpase
AWV81_07760	COG0006	proline dipeptidase activity
AWV81_07770	COG1609	Transcriptional regulator
AWV81_07775	COG3711	transcriptional antiterminator
AWV81_07780	COG1263	PTS System
AWV81_07780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_07780	COG2190	(PTS) system
AWV81_07785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_07790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWV81_07800	COG1533	DNA photolyase activity
AWV81_07805	COG0456	acetyltransferase
AWV81_07810	COG0840	transmembrane signaling receptor activity
AWV81_07815	COG2084	Dehydrogenase
AWV81_07820	COG3328	transposase activity
AWV81_07825	COG2340	Cysteine-rich secretory protein family
AWV81_07830	COG0768	penicillin binding
AWV81_07835	COG4191	Histidine kinase
AWV81_07840	COG0436	Aminotransferase
AWV81_07850	COG0835	chemotaxis
AWV81_07850	COG0784	Response regulator, receiver
AWV81_07860	COG2814	Major facilitator Superfamily
AWV81_07865	COG1376	ErfK ybiS ycfS ynhG family protein
AWV81_07870	COG1408	metallophosphoesterase
AWV81_07875	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_07880	COG2200	EAL domain
AWV81_07890	COG4703	Protein of unknown function (DUF1797)
AWV81_07895	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AWV81_07905	COG0517	IMP dehydrogenase activity
AWV81_07910	COG0583	DNA-binding transcription factor activity
AWV81_07915	COG0716	FMN binding
AWV81_07925	COG0716	FMN binding
AWV81_07930	COG2171	N-acyltransferase activity
AWV81_07935	COG1473	amidohydrolase
AWV81_07945	COG0668	transmembrane transport
AWV81_07950	COG0450	alkyl hydroperoxide reductase
AWV81_07955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_07965	COG2801	Transposase and inactivated derivatives
AWV81_07980	COG0746	molybdenum cofactor guanylyltransferase activity
AWV81_07985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_07990	COG0303	'Molybdopterin
AWV81_07995	COG1763	Mo-molybdopterin cofactor biosynthetic process
AWV81_08000	COG0314	molybdopterin synthase activity
AWV81_08005	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWV81_08015	COG1132	(ABC) transporter
AWV81_08025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWV81_08030	COG1136	(ABC) transporter
AWV81_08035	COG0577	efflux transmembrane transporter activity
AWV81_08040	COG1349	DNA-binding transcription factor activity
AWV81_08045	COG1105	Belongs to the carbohydrate kinase PfkB family
AWV81_08050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_08050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWV81_08050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_08055	COG0681	Belongs to the peptidase S26 family
AWV81_08065	COG0488	(ABC) transporter
AWV81_08070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWV81_08075	COG2309	aminopeptidase activity
AWV81_08085	COG1077	Cell shape determining protein MreB Mrl
AWV81_08090	COG2002	toxin-antitoxin pair type II binding
AWV81_08095	COG3852	Histidine kinase
AWV81_08100	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AWV81_08100	COG2105	PFAM AIG2 family protein
AWV81_08105	COG0569	domain protein
AWV81_08110	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AWV81_08115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWV81_08125	COG0561	phosphatase activity
AWV81_08130	COG0242	peptide deformylase activity
AWV81_08145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWV81_08150	COG0022	dehydrogenase e1 component
AWV81_08155	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_08160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWV81_08165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_08170	COG1982	Orn Lys Arg decarboxylase major
AWV81_08175	COG4476	Belongs to the UPF0223 family
AWV81_08180	COG4493	Belongs to the UPF0637 family
AWV81_08190	COG0483	inositol monophosphate 1-phosphatase activity
AWV81_08205	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AWV81_08260	COG4896	Protein conserved in bacteria
AWV81_08270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWV81_08275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWV81_08280	COG2066	Belongs to the glutaminase family
AWV81_08285	COG4838	Belongs to the UPF0358 family
AWV81_08290	COG0772	Belongs to the SEDS family
AWV81_08295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AWV81_08300	COG1612	heme a metabolic process
AWV81_08305	COG0109	protoheme IX farnesyltransferase activity
AWV81_08310	COG2010	Cytochrome c
AWV81_08310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWV81_08315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWV81_08320	COG1845	cytochrome c oxidase, subunit III
AWV81_08325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWV81_08330	COG3336	cytochrome c oxidase
AWV81_08340	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AWV81_08345	COG2340	Cysteine-rich secretory protein family
AWV81_08360	COG3679	Belongs to the UPF0342 family
AWV81_08365	COG4471	UPF0298 protein
AWV81_08370	COG0742	ribosomal rna small subunit methyltransferase
AWV81_08375	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWV81_08380	COG3314	Sporulation integral membrane protein YlbJ
AWV81_08385	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWV81_08390	COG3480	Lon protease (S16) C-terminal proteolytic domain
AWV81_08395	COG1323	Belongs to the UPF0348 family
AWV81_08405	COG1399	metal-binding, possibly nucleic acid-binding protein
AWV81_08410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWV81_08420	COG0454	-acetyltransferase
AWV81_08425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWV81_08430	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AWV81_08435	COG2001	Belongs to the MraZ family
AWV81_08440	COG0275	rRNA processing
AWV81_08445	COG4839	cell division protein FtsL
AWV81_08460	COG0768	penicillin binding
AWV81_08470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWV81_08480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWV81_08485	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWV81_08490	COG0772	Belongs to the SEDS family
AWV81_08495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWV81_08500	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWV81_08505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AWV81_08510	COG3879	Bacterial protein of unknown function (DUF881)
AWV81_08515	COG3879	Bacterial protein of unknown function (DUF881)
AWV81_08520	COG3856	small basic protein
AWV81_08525	COG0849	cell division
AWV81_08530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWV81_08535	COG4412	M6 family metalloprotease domain protein
AWV81_08535	COG1404	Belongs to the peptidase S8 family
AWV81_08545	COG1191	sigma factor activity
AWV81_08550	COG1191	sigma factor activity
AWV81_08555	COG1119	ATPase activity
AWV81_08560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_08565	COG1873	PFAM PRC-barrel domain
AWV81_08575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWV81_08580	COG1799	cell septum assembly
AWV81_08585	COG0762	integral membrane protein
AWV81_08590	COG2302	S4 RNA-binding domain
AWV81_08595	COG3599	regulation of cell shape
AWV81_08600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWV81_08605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWV81_08610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWV81_08615	COG0564	pseudouridine synthase activity
AWV81_08620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWV81_08625	COG2233	PERMEase
AWV81_08630	COG0540	Belongs to the ATCase OTCase family
AWV81_08635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWV81_08640	COG0505	Belongs to the CarA family
AWV81_08645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWV81_08650	COG0543	2 iron, 2 sulfur cluster binding
AWV81_08655	COG0167	dihydroorotate dehydrogenase activity
AWV81_08660	COG0284	orotidine-5'-phosphate decarboxylase activity
AWV81_08665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWV81_08670	COG0175	sulfate reduction
AWV81_08675	COG0306	phosphate transporter
AWV81_08680	COG2046	Belongs to the sulfate adenylyltransferase family
AWV81_08685	COG0529	Catalyzes the synthesis of activated sulfate
AWV81_08690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWV81_08695	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AWV81_08700	COG1648	precorrin-2 dehydrogenase activity
AWV81_08710	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWV81_08715	COG1561	YicC-like family, N-terminal region
AWV81_08720	COG2052	Domain of unknown function (DUF370)
AWV81_08725	COG0194	GDP metabolic process
AWV81_08730	COG1758	RNA polymerase activity
AWV81_08735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWV81_08740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWV81_08745	COG0242	peptide deformylase activity
AWV81_08750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWV81_08755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWV81_08755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWV81_08760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWV81_08765	COG0631	protein serine/threonine phosphatase activity
AWV81_08770	COG2815	serine threonine protein kinase
AWV81_08770	COG0515	serine threonine protein kinase
AWV81_08775	COG1162	GTPase activity
AWV81_08780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWV81_08785	COG1564	THIamine pyrophosphokinase
AWV81_08795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWV81_08800	COG1302	Protein conserved in bacteria
AWV81_08805	COG1461	Dihydroxyacetone kinase
AWV81_08810	COG1760	l-serine dehydratase
AWV81_08815	COG1760	l-serine dehydratase
AWV81_08820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWV81_08825	COG2050	protein possibly involved in aromatic compounds catabolism
AWV81_08825	COG1349	DNA-binding transcription factor activity
AWV81_08830	COG0416	fatty acid biosynthetic process
AWV81_08835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWV81_08840	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_08845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWV81_08850	COG0571	ribonuclease III activity
AWV81_08855	COG1196	nuclear chromosome segregation
AWV81_08860	COG0552	protein localization to endoplasmic reticulum
AWV81_08870	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AWV81_08875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWV81_08880	COG0228	four-way junction DNA binding
AWV81_08885	COG1837	Belongs to the UPF0109 family
AWV81_08895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWV81_08900	COG0336	Belongs to the RNA methyltransferase TrmD family
AWV81_08905	COG0335	large ribosomal subunit rRNA binding
AWV81_08910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWV81_08915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWV81_08925	COG2257	FlhB HrpN YscU SpaS Family
AWV81_08930	COG0045	succinate-CoA ligase (ADP-forming) activity
AWV81_08935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AWV81_08940	COG0758	DNA mediated transformation
AWV81_08945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWV81_08950	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWV81_08955	COG4974	Belongs to the 'phage' integrase family
AWV81_08960	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AWV81_08965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AWV81_08970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AWV81_08975	COG1815	bacterial-type flagellum-dependent cell motility
AWV81_08980	COG1558	bacterial-type flagellum-dependent cell motility
AWV81_08985	COG1677	Flagellar hook-basal body complex protein FliE
AWV81_08995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWV81_09000	COG1317	bacterial-type flagellum organization
AWV81_09005	COG1157	protein secretion by the type III secretion system
AWV81_09010	COG2882	bacterial-type flagellum organization
AWV81_09015	COG3334	PFAM MgtE intracellular
AWV81_09020	COG3144	bacterial-type flagellum assembly
AWV81_09025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AWV81_09030	COG4786	Flagellar basal body rod
AWV81_09035	COG1582	Flagellar protein (FlbD)
AWV81_09040	COG1580	Controls the rotational direction of flagella during chemotaxis
AWV81_09045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWV81_09050	COG1776	CheC inhibitor of MCP methylation
AWV81_09050	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AWV81_09055	COG2201	protein-glutamate methylesterase activity
AWV81_09060	COG3190	flagellar
AWV81_09065	COG1338	Plays a role in the flagellum-specific transport system
AWV81_09070	COG1987	bacterial-type flagellum assembly
AWV81_09075	COG1684	flagellar biosynthetic protein fliR
AWV81_09080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWV81_09085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AWV81_09090	COG1419	protein localization to endoplasmic reticulum
AWV81_09095	COG0455	bacterial-type flagellum organization
AWV81_09100	COG2201	protein-glutamate methylesterase activity
AWV81_09105	COG2198	Histidine kinase
AWV81_09105	COG0643	Histidine kinase
AWV81_09110	COG0835	chemotaxis
AWV81_09120	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AWV81_09125	COG1191	sigma factor activity
AWV81_09135	COG0052	Belongs to the universal ribosomal protein uS2 family
AWV81_09140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWV81_09145	COG0528	UMP kinase activity
AWV81_09150	COG0233	cytoplasmic translational termination
AWV81_09155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWV81_09160	COG4589	Belongs to the CDS family
AWV81_09165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWV81_09170	COG0750	zinc metalloprotease
AWV81_09175	COG0442	prolyl-tRNA aminoacylation
AWV81_09180	COG2176	DNA-directed DNA polymerase activity
AWV81_09185	COG0779	Required for maturation of 30S ribosomal subunits
AWV81_09190	COG0195	Participates in both transcription termination and antitermination
AWV81_09195	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AWV81_09200	COG1358	cellular component organization or biogenesis
AWV81_09205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWV81_09210	COG1550	Protein conserved in bacteria
AWV81_09215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWV81_09220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWV81_09225	COG0196	riboflavin kinase activity
AWV81_09230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWV81_09235	COG1185	polyribonucleotide nucleotidyltransferase activity
AWV81_09240	COG0726	polysaccharide deacetylase
AWV81_09245	COG0612	Peptidase, M16
AWV81_09250	COG1873	PFAM PRC-barrel domain
AWV81_09260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWV81_09265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWV81_09270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWV81_09275	COG0527	aspartate kinase activity
AWV81_09280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWV81_09285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWV81_09290	COG0740	serine-type endopeptidase activity
AWV81_09300	COG4980	gas vesicle protein
AWV81_09300	COG1674	ftsk spoiiie
AWV81_09305	COG2188	Transcriptional regulator
AWV81_09310	COG2814	Major facilitator Superfamily
AWV81_09315	COG0612	Peptidase, M16
AWV81_09320	COG0612	Peptidase, M16
AWV81_09325	COG0300	oxidoreductase activity
AWV81_09340	COG1426	Protein conserved in bacteria
AWV81_09345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWV81_09350	COG1546	Belongs to the CinA family
AWV81_09350	COG1058	Belongs to the CinA family
AWV81_09355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWV81_09360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWV81_09365	COG1418	mRNA catabolic process
AWV81_09370	COG1692	metallophosphoesterase
AWV81_09375	COG2359	stage V sporulation protein S
AWV81_09380	COG1063	alcohol dehydrogenase
AWV81_09385	COG0156	8-amino-7-oxononanoate synthase activity
AWV81_09390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWV81_09395	COG4550	Control of competence regulator ComK, YlbF/YmcA
AWV81_09405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWV81_09410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWV81_09515	COG3226	Transcriptional regulator
AWV81_09525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_09530	COG1404	Belongs to the peptidase S8 family
AWV81_09540	COG4195	phage-related replication protein
AWV81_09545	COG1764	response to oxidative stress
AWV81_09550	COG2076	Multidrug Resistance protein
AWV81_09555	COG2076	Multidrug Resistance protein
AWV81_09570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWV81_09575	COG1923	regulation of RNA biosynthetic process
AWV81_09590	COG1780	Probably involved in ribonucleotide reductase function
AWV81_09595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWV81_09600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWV81_09605	COG4112	unkown
AWV81_09610	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_09615	COG0464	growth
AWV81_09625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWV81_09630	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWV81_09635	COG0789	Transcriptional regulator
AWV81_09640	COG0174	glutamine synthetase
AWV81_09645	COG4974	Belongs to the 'phage' integrase family
AWV81_09665	COG3646	Phage regulatory protein
AWV81_09665	COG3645	SOS response
AWV81_09810	COG5412	phage tail tape measure protein
AWV81_09810	COG3953	SLT domain
AWV81_09850	COG1388	LysM domain
AWV81_09850	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_09850	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_09860	COG5444	nuclease activity
AWV81_09895	COG4282	regulation of fungal-type cell wall biogenesis
AWV81_09915	COG3328	transposase activity
AWV81_09930	COG3655	Transcriptional regulator
AWV81_09955	COG0135	phosphoribosylanthranilate isomerase activity
AWV81_09960	COG2211	Major facilitator Superfamily
AWV81_09975	COG3507	Belongs to the glycosyl hydrolase 43 family
AWV81_09980	COG1940	carbohydrate kinase activity
AWV81_09985	COG2115	Belongs to the xylose isomerase family
AWV81_09990	COG1070	Carbohydrate kinase
AWV81_09995	COG3328	transposase activity
AWV81_10000	COG1525	nuclease
AWV81_10005	COG2814	Major facilitator Superfamily
AWV81_10010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWV81_10025	COG0756	dUTP diphosphatase activity
AWV81_10065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWV81_10085	COG3832	glyoxalase III activity
AWV81_10130	COG4195	phage-related replication protein
AWV81_10140	COG0346	lactoylglutathione lyase activity
AWV81_10150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWV81_10155	COG1388	LysM domain
AWV81_10160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AWV81_10165	COG4224	UPF0291 protein
AWV81_10170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWV81_10180	COG3763	UPF0154 protein
AWV81_10190	COG0785	Cytochrome C biogenesis protein
AWV81_10195	COG2201	protein-glutamate methylesterase activity
AWV81_10200	COG4846	Membrane protein involved in cytochrome C biogenesis
AWV81_10210	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_10225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AWV81_10230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_10250	COG0824	Thioesterase
AWV81_10260	COG4841	protein insertion into membrane
AWV81_10265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AWV81_10270	COG1832	CoA-binding protein
AWV81_10275	COG0187	DNA topoisomerase II activity
AWV81_10280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWV81_10295	COG1115	amino acid carrier protein
AWV81_10300	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AWV81_10310	COG5520	Belongs to the glycosyl hydrolase 30 family
AWV81_10320	COG2246	polysaccharide biosynthetic process
AWV81_10325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWV81_10330	COG0586	Pfam SNARE associated Golgi protein
AWV81_10335	COG2404	hydrolase activity, acting on ester bonds
AWV81_10340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AWV81_10345	COG1024	Enoyl-CoA hydratase
AWV81_10350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWV81_10355	COG0511	ligase activity, forming carbon-carbon bonds
AWV81_10360	COG0439	Biotin carboxylase
AWV81_10365	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_10370	COG1960	acyl-CoA dehydrogenase activity
AWV81_10380	COG1649	PFAM Uncharacterised BCR, COG1649
AWV81_10395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_10400	COG2027	D-alanyl-D-alanine carboxypeptidase
AWV81_10405	COG2017	converts alpha-aldose to the beta-anomer
AWV81_10410	COG0534	Mate efflux family protein
AWV81_10425	COG2801	Transposase and inactivated derivatives
AWV81_10435	COG0582	viral genome integration into host DNA
AWV81_10440	COG0166	Belongs to the GPI family
AWV81_10445	COG0405	Gamma-glutamyltransferase
AWV81_10450	COG0583	DNA-binding transcription factor activity
AWV81_10455	COG0604	alcohol dehydrogenase
AWV81_10460	COG0493	'glutamate synthase
AWV81_10465	COG0067	glutamate synthase
AWV81_10465	COG0069	glutamate synthase activity
AWV81_10465	COG0070	glutamate synthase
AWV81_10470	COG0583	DNA-binding transcription factor activity
AWV81_10495	COG0300	oxidoreductase activity
AWV81_10500	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AWV81_10510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_10525	COG1131	(ABC) transporter
AWV81_10535	COG2814	Major facilitator Superfamily
AWV81_10540	COG3328	transposase activity
AWV81_10565	COG2801	Transposase and inactivated derivatives
AWV81_10585	COG3328	transposase activity
AWV81_10640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_10645	COG2226	methyltransferase
AWV81_10650	COG2211	Major facilitator Superfamily
AWV81_10660	COG3328	transposase activity
AWV81_10685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWV81_10705	COG5444	nuclease activity
AWV81_10710	COG4282	regulation of fungal-type cell wall biogenesis
AWV81_10715	COG1231	oxidoreductase activity
AWV81_10720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_10725	COG2207	Transcriptional regulator
AWV81_10725	COG0662	Cupin 2, conserved barrel domain protein
AWV81_10730	COG0456	acetyltransferase
AWV81_10735	COG1309	transcriptional regulator
AWV81_10740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_10745	COG3708	Transcriptional regulator
AWV81_10750	COG2378	regulation of single-species biofilm formation
AWV81_10760	COG0640	Transcriptional regulator
AWV81_10765	COG0741	lytic transglycosylase activity
AWV81_10770	COG2322	membrane
AWV81_10785	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWV81_10790	COG3239	Fatty acid desaturase
AWV81_10795	COG4585	Histidine kinase
AWV81_10800	COG2197	response regulator
AWV81_10805	COG1388	LysM domain
AWV81_10805	COG3584	3D domain protein
AWV81_10810	COG0514	ATP-dependent DNA helicase (RecQ)
AWV81_10825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AWV81_10830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWV81_10845	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_10870	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_10875	COG1657	PFAM Prenyltransferase squalene oxidase
AWV81_10880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWV81_10885	COG0733	neurotransmitter:sodium symporter activity
AWV81_10890	COG0385	Bile acid
AWV81_10895	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_10900	COG0567	Dehydrogenase, E1 component
AWV81_10905	COG4548	von Willebrand factor, type A
AWV81_10910	COG0714	Associated with various cellular activities
AWV81_10915	COG2032	superoxide dismutase activity
AWV81_10920	COG1388	LysM domain
AWV81_10920	COG0791	NLP P60 protein
AWV81_10925	COG1819	glycosyl
AWV81_10930	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWV81_10935	COG0534	Mate efflux family protein
AWV81_10940	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_10945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWV81_10950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWV81_10960	COG2962	Rard protein
AWV81_10980	COG1942	4-Oxalocrotonate Tautomerase
AWV81_10985	COG1733	regulation of RNA biosynthetic process
AWV81_10990	COG0778	Nitroreductase
AWV81_11000	COG2801	Transposase and inactivated derivatives
AWV81_11005	COG0400	carboxylic ester hydrolase activity
AWV81_11020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_11025	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_11025	COG0793	Belongs to the peptidase S41A family
AWV81_11030	COG2226	methyltransferase
AWV81_11040	COG1876	peptidase activity
AWV81_11045	COG0813	purine-nucleoside phosphorylase activity
AWV81_11060	COG0671	phosphoesterase, PA-phosphatase related
AWV81_11085	COG4479	Belongs to the UPF0346 family
AWV81_11095	COG1509	lysine 2,3-aminomutase activity
AWV81_11100	COG0456	acetyltransferase
AWV81_11105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_11110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWV81_11115	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWV81_11120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWV81_11135	COG0456	acetyltransferase
AWV81_11140	COG0463	Glycosyl transferase, family 2
AWV81_11155	COG4641	Protein conserved in bacteria
AWV81_11160	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AWV81_11165	COG1086	Polysaccharide biosynthesis protein
AWV81_11170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWV81_11175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWV81_11180	COG1846	Transcriptional regulator
AWV81_11185	COG0534	Mate efflux family protein
AWV81_11195	COG4698	Protein conserved in bacteria
AWV81_11200	COG2755	lipolytic protein G-D-S-L family
AWV81_11205	COG1999	signal sequence binding
AWV81_11220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWV81_11225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AWV81_11230	COG1272	protein, Hemolysin III
AWV81_11235	COG0204	Acyl-transferase
AWV81_11240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWV81_11245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWV81_11255	COG2136	Putative SAM-dependent methyltransferase
AWV81_11255	COG2521	methyltransferase
AWV81_11265	COG0129	dihydroxy-acid dehydratase activity
AWV81_11270	COG1413	lyase activity
AWV81_11275	COG1418	mRNA catabolic process
AWV81_11280	COG0386	Belongs to the glutathione peroxidase family
AWV81_11285	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AWV81_11290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWV81_11295	COG1278	Cold shock
AWV81_11315	COG0328	RNA-DNA hybrid ribonuclease activity
AWV81_11320	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AWV81_11325	COG0328	RNA-DNA hybrid ribonuclease activity
AWV81_11335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWV81_11355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AWV81_11360	COG1755	Isoprenylcysteine carboxyl methyltransferase
AWV81_11365	COG3424	synthase
AWV81_11370	COG2233	PERMEase
AWV81_11375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWV81_11380	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AWV81_11390	COG0800	Aldolase
AWV81_11395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_11400	COG1609	Transcriptional regulator
AWV81_11405	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AWV81_11410	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_11415	COG1199	ATP-dependent helicase activity
AWV81_11425	COG0116	Belongs to the methyltransferase superfamily
AWV81_11440	COG4474	Belongs to the UPF0398 family
AWV81_11450	COG3359	exonuclease
AWV81_11455	COG1111	helicase
AWV81_11455	COG1205	dead DEAH box helicase
AWV81_11460	COG2190	(PTS) system
AWV81_11465	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_11500	COG3331	DNA recombination
AWV81_11505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_11505	COG4499	WXG100 protein secretion system (Wss), protein YukC
AWV81_11515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWV81_11520	COG3935	DnaD domain protein
AWV81_11525	COG0017	Asparaginyl-tRNA synthetase
AWV81_11530	COG0436	Aminotransferase
AWV81_11535	COG5353	protein conserved in bacteria
AWV81_11545	COG1199	ATP-dependent helicase activity
AWV81_11545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWV81_11550	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AWV81_11555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWV81_11560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWV81_11565	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWV81_11565	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWV81_11570	COG0617	tRNA 3'-terminal CCA addition
AWV81_11575	COG0438	transferase activity, transferring glycosyl groups
AWV81_11580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AWV81_11585	COG1803	Methylglyoxal synthase
AWV81_11590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWV81_11595	COG1694	Mazg nucleotide pyrophosphohydrolase
AWV81_11600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_11610	COG4347	Protein of unknown function (DUF1405)
AWV81_11615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWV81_11615	COG2010	Cytochrome c
AWV81_11620	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWV81_11625	COG0723	plastoquinol--plastocyanin reductase activity
AWV81_11635	COG5582	Belongs to the UPF0302 family
AWV81_11640	COG0457	Tetratricopeptide repeat
AWV81_11645	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWV81_11650	COG0287	Prephenate dehydrogenase
AWV81_11665	COG0133	tryptophan synthase activity
AWV81_11670	COG0135	phosphoribosylanthranilate isomerase activity
AWV81_11680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWV81_11685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWV81_11690	COG4401	Chorismate mutase type I
AWV81_11695	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWV81_11700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWV81_11705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AWV81_11715	COG0105	UTP biosynthetic process
AWV81_11720	COG0142	geranyltranstransferase activity
AWV81_11725	COG2226	methyltransferase
AWV81_11730	COG0142	geranyltranstransferase activity
AWV81_11740	COG0302	gtp cyclohydrolase
AWV81_11745	COG0776	regulation of translation
AWV81_11750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AWV81_11765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWV81_11770	COG1160	GTP binding
AWV81_11795	COG1304	FMN binding
AWV81_11800	COG0539	negative regulation of cytoplasmic translation
AWV81_11805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWV81_11815	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AWV81_11820	COG2959	enzyme of heme biosynthesis
AWV81_11825	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_11825	COG3773	Cell wall hydrolase
AWV81_11830	COG2339	peptidase activity
AWV81_11835	COG0492	ferredoxin-NADP+ reductase activity
AWV81_11840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWV81_11845	COG4862	establishment of competence for transformation
AWV81_11850	COG1408	metallophosphoesterase
AWV81_11860	COG1388	LysM domain
AWV81_11865	COG1266	CAAX protease self-immunity
AWV81_11870	COG0514	ATP-dependent DNA helicase (RecQ)
AWV81_11875	COG4955	Helix-turn-helix domain
AWV81_11880	COG1141	Ferredoxin
AWV81_11885	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AWV81_11890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWV81_11895	COG0710	3-dehydroquinate dehydratase activity
AWV81_11905	COG1595	DNA-templated transcription, initiation
AWV81_11910	COG5002	protein histidine kinase activity
AWV81_11915	COG0745	RESPONSE REGULATOR receiver
AWV81_11920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWV81_11925	COG1333	cytochrome c biogenesis protein
AWV81_11930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_11935	COG1187	pseudouridine synthase activity
AWV81_11940	COG0700	Nucleoside recognition
AWV81_11945	COG2715	membrane protein required for spore maturation
AWV81_11950	COG1686	Belongs to the peptidase S11 family
AWV81_11960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AWV81_11965	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AWV81_11970	COG1547	Domain of unknown function (DUF309)
AWV81_11975	COG0456	acetyltransferase
AWV81_11980	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWV81_11985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWV81_11985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWV81_11990	COG0307	riboflavin synthase, alpha
AWV81_11995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWV81_11995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWV81_12005	COG0681	Belongs to the peptidase S26 family
AWV81_12015	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AWV81_12030	COG2433	Pfam Transposase IS66
AWV81_12060	COG3328	transposase activity
AWV81_12110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWV81_12120	COG4086	secreted protein
AWV81_12125	COG0019	diaminopimelate decarboxylase activity
AWV81_12130	COG0697	spore germination
AWV81_12145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWV81_12165	COG1191	sigma factor activity
AWV81_12170	COG2172	sigma factor antagonist activity
AWV81_12175	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_12180	COG1686	Belongs to the peptidase S11 family
AWV81_12185	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWV81_12190	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AWV81_12195	COG4974	Belongs to the 'phage' integrase family
AWV81_12205	COG0735	belongs to the Fur family
AWV81_12210	COG1300	Membrane
AWV81_12220	COG0281	malic enzyme
AWV81_12225	COG1757	Na H antiporter
AWV81_12230	COG1027	Aspartate ammonia-lyase
AWV81_12235	COG0252	asparaginase activity
AWV81_12240	COG1396	sequence-specific DNA binding
AWV81_12245	COG1379	DNA repair
AWV81_12250	COG0494	nUDIX hydrolase
AWV81_12260	COG0667	Aldo Keto reductase
AWV81_12270	COG1073	alpha beta
AWV81_12280	COG4918	Iron-sulphur cluster biosynthesis
AWV81_12285	COG0456	acetyltransferase
AWV81_12285	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AWV81_12290	COG2329	Antibiotic biosynthesis monooxygenase
AWV81_12295	COG0456	acetyltransferase
AWV81_12305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWV81_12315	COG2211	Major facilitator Superfamily
AWV81_12325	COG0346	lactoylglutathione lyase activity
AWV81_12330	COG1072	(Pantothenic acid kinase))
AWV81_12335	COG3048	D-serine ammonia-lyase activity
AWV81_12340	COG0300	oxidoreductase activity
AWV81_12345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_12350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_12355	COG4187	Peptidase family M20/M25/M40
AWV81_12360	COG1902	pentaerythritol trinitrate reductase activity
AWV81_12370	COG0511	ligase activity, forming carbon-carbon bonds
AWV81_12375	COG0439	Biotin carboxylase
AWV81_12380	COG1302	Protein conserved in bacteria
AWV81_12385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWV81_12390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWV81_12395	COG1570	exodeoxyribonuclease VII activity
AWV81_12400	COG1722	exodeoxyribonuclease VII activity
AWV81_12405	COG0142	geranyltranstransferase activity
AWV81_12410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWV81_12415	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWV81_12420	COG1438	arginine binding
AWV81_12425	COG0497	DNA recombination
AWV81_12430	COG0750	zinc metalloprotease
AWV81_12440	COG0745	RESPONSE REGULATOR receiver
AWV81_12450	COG1902	pentaerythritol trinitrate reductase activity
AWV81_12465	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_12470	COG0584	glycerophosphoryl diester phosphodiesterase
AWV81_12475	COG0183	Belongs to the thiolase family
AWV81_12480	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWV81_12485	COG1960	acyl-CoA dehydrogenase activity
AWV81_12490	COG0372	Belongs to the citrate synthase family
AWV81_12495	COG2079	MmgE PrpD family protein
AWV81_12500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AWV81_12510	COG3829	transcription factor binding
AWV81_12510	COG3290	protein histidine kinase activity
AWV81_12515	COG0280	phosphate acetyltransferase
AWV81_12520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWV81_12525	COG3426	butyrate kinase activity
AWV81_12530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWV81_12535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWV81_12540	COG0022	dehydrogenase e1 component
AWV81_12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWV81_12550	COG0789	Transcriptional regulator
AWV81_12550	COG4978	Transcriptional regulator
AWV81_12560	COG1597	lipid kinase activity
AWV81_12570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_12575	COG0765	amino acid transport
AWV81_12580	COG1126	abc transporter atp-binding protein
AWV81_12585	COG4129	membrane
AWV81_12590	COG1376	ErfK ybiS ycfS ynhG family protein
AWV81_12600	COG0346	lactoylglutathione lyase activity
AWV81_12610	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWV81_12615	COG3361	conserved protein (COG2071)
AWV81_12620	COG0706	membrane insertase activity
AWV81_12630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWV81_12635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWV81_12640	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWV81_12645	COG1234	tRNA 3'-trailer cleavage
AWV81_12655	COG0596	Alpha beta hydrolase
AWV81_12700	COG3854	ATPases associated with a variety of cellular activities
AWV81_12710	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWV81_12715	COG0006	proline dipeptidase activity
AWV81_12720	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWV81_12730	COG3872	metal-dependent enzyme
AWV81_12740	COG1752	Esterase of the alpha-beta hydrolase superfamily
AWV81_12745	COG1321	iron dependent repressor
AWV81_12750	COG0095	Lipoate-protein ligase
AWV81_12755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWV81_12760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWV81_12765	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWV81_12770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWV81_12775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWV81_12790	COG1396	sequence-specific DNA binding
AWV81_12800	COG0681	Belongs to the peptidase S26 family
AWV81_12825	COG4940	Competence protein ComGF
AWV81_12835	COG4970	Tfp pilus assembly protein FimT
AWV81_12840	COG4537	Required for transformation and DNA binding
AWV81_12845	COG1459	type II secretion system
AWV81_12850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWV81_12860	COG0517	IMP dehydrogenase activity
AWV81_12865	COG0598	Magnesium transport protein CorA
AWV81_12870	COG1253	flavin adenine dinucleotide binding
AWV81_12875	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_12885	COG1393	Belongs to the ArsC family
AWV81_12895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_12905	COG0011	TIGRFAM Protein of
AWV81_12915	COG2866	Carboxypeptidase
AWV81_12920	COG1368	sulfuric ester hydrolase activity
AWV81_12925	COG1940	carbohydrate kinase activity
AWV81_12930	COG4483	Protein conserved in bacteria
AWV81_12935	COG0705	Rhomboid family
AWV81_12935	COG0457	Tetratricopeptide repeat
AWV81_12945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AWV81_12950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AWV81_12955	COG0438	transferase activity, transferring glycosyl groups
AWV81_12970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWV81_12975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWV81_12980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWV81_12985	COG0581	inorganic phosphate transmembrane transporter activity
AWV81_12990	COG0573	inorganic phosphate transmembrane transporter activity
AWV81_12995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWV81_13005	COG0477	Major facilitator Superfamily
AWV81_13010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWV81_13015	COG2839	Protein conserved in bacteria
AWV81_13020	COG5521	maltodextrose utilization protein MalA
AWV81_13025	COG1388	LysM domain
AWV81_13030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWV81_13035	COG4709	membrane
AWV81_13040	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AWV81_13045	COG0735	belongs to the Fur family
AWV81_13050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_13060	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AWV81_13065	COG0513	Belongs to the DEAD box helicase family
AWV81_13075	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWV81_13080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AWV81_13085	COG2384	SAM-dependent methyltransferase
AWV81_13090	COG2010	Cytochrome c
AWV81_13095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWV81_13100	COG0358	DNA primase activity
AWV81_13105	COG1671	Belongs to the UPF0178 family
AWV81_13110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AWV81_13115	COG0517	IMP dehydrogenase activity
AWV81_13120	COG0751	glycine-tRNA ligase activity
AWV81_13125	COG0752	glycyl-tRNA synthetase alpha subunit
AWV81_13130	COG1381	Involved in DNA repair and RecF pathway recombination
AWV81_13140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWV81_13145	COG0295	cytidine deaminase activity
AWV81_13150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWV81_13155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWV81_13160	COG1480	7TM receptor with intracellular HD hydrolase
AWV81_13170	COG1702	phosphate starvation-inducible protein PhoH
AWV81_13175	COG0561	phosphatase activity
AWV81_13190	COG4864	UPF0365 protein
AWV81_13195	COG1030	water channel activity
AWV81_13200	COG1610	YqeY-like protein
AWV81_13205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AWV81_13210	COG1283	sodium-dependent phosphate transmembrane transporter activity
AWV81_13215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWV81_13220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWV81_13225	COG2264	protein methyltransferase activity
AWV81_13230	COG0484	heat shock protein binding
AWV81_13235	COG0443	Heat shock 70 kDa protein
AWV81_13240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWV81_13245	COG1420	regulation of RNA biosynthetic process
AWV81_13250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWV81_13255	COG0481	GTPase activity
AWV81_13265	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_13270	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AWV81_13275	COG0268	Binds directly to 16S ribosomal RNA
AWV81_13280	COG1466	dna polymerase III delta subunit
AWV81_13290	COG2333	competence protein COMEC
AWV81_13290	COG0658	competence protein
AWV81_13295	COG2131	deaminase
AWV81_13300	COG1555	photosystem II stabilization
AWV81_13300	COG1596	polysaccharide export
AWV81_13305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWV81_13310	COG2226	methyltransferase
AWV81_13315	COG0799	negative regulation of ribosome biogenesis
AWV81_13320	COG1713	HD superfamily hydrolase involved in NAD metabolism
AWV81_13325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWV81_13330	COG1534	Rna-binding protein
AWV81_13335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWV81_13340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWV81_13345	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWV81_13360	COG2755	lipolytic protein G-D-S-L family
AWV81_13365	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_13365	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_13370	COG0398	Pfam SNARE associated Golgi protein
AWV81_13375	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AWV81_13385	COG3209	COG3209 Rhs family protein
AWV81_13405	COG0114	fumarate hydratase activity
AWV81_13410	COG0583	DNA-binding transcription factor activity
AWV81_13420	COG0457	Tetratricopeptide repeat
AWV81_13525	COG4978	Transcriptional regulator
AWV81_13525	COG0789	Transcriptional regulator
AWV81_13530	COG2814	Major facilitator Superfamily
AWV81_13535	COG0456	acetyltransferase
AWV81_13540	COG1253	flavin adenine dinucleotide binding
AWV81_13550	COG0697	spore germination
AWV81_13555	COG0583	DNA-binding transcription factor activity
AWV81_13560	COG2072	flavoprotein involved in K transport
AWV81_13565	COG1230	cation diffusion facilitator family transporter
AWV81_13575	COG1114	Component of the transport system for branched-chain amino acids
AWV81_13580	COG1687	branched-chain amino acid
AWV81_13590	COG1522	sequence-specific DNA binding
AWV81_13595	COG2732	(Barnase) inhibitor
AWV81_13600	COG2124	cytochrome p450
AWV81_13615	COG1335	isochorismatase
AWV81_13625	COG2318	DinB family
AWV81_13635	COG2070	2-Nitropropane dioxygenase
AWV81_13640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWV81_13655	COG3443	Belongs to the bacterial solute-binding protein 9 family
AWV81_13660	COG1595	DNA-templated transcription, initiation
AWV81_13665	COG0667	Aldo Keto reductase
AWV81_13670	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_13675	COG5566	PFAM Mor transcription activator
AWV81_13680	COG0596	Alpha beta hydrolase
AWV81_13685	COG4991	sh3 domain protein
AWV81_13690	COG4991	sh3 domain protein
AWV81_13695	COG0346	lactoylglutathione lyase activity
AWV81_13705	COG5577	PFAM Coat F domain
AWV81_13710	COG1063	alcohol dehydrogenase
AWV81_13720	COG5577	PFAM Coat F domain
AWV81_13725	COG0789	Transcriptional regulator
AWV81_13735	COG1064	alcohol dehydrogenase
AWV81_13740	COG0693	protein deglycase activity
AWV81_13745	COG1621	beta-fructofuranosidase activity
AWV81_13750	COG3716	PTS system mannose fructose sorbose family IID component
AWV81_13755	COG3715	PTS system
AWV81_13760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_13765	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_13770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AWV81_13770	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AWV81_13775	COG1113	amino acid transport
AWV81_13780	COG1280	lysine exporter protein (LysE YggA)
AWV81_13785	COG1378	Sugar-specific transcriptional regulator TrmB
AWV81_13790	COG1595	DNA-templated transcription, initiation
AWV81_13815	COG1309	transcriptional regulator
AWV81_13820	COG2226	methyltransferase
AWV81_13830	COG2116	formate transmembrane transporter activity
AWV81_13835	COG5609	conserved protein (DUF2294)
AWV81_13840	COG3383	formate dehydrogenase (NAD+) activity
AWV81_13845	COG2427	Protein of unknown function (DUF1641)
AWV81_13860	COG0626	cystathionine gamma-synthase activity
AWV81_13865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWV81_13870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWV81_13875	COG2226	methyltransferase
AWV81_13890	COG0768	penicillin binding
AWV81_13895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AWV81_13900	COG0572	uridine kinase
AWV81_13920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWV81_13925	COG3906	Belongs to the UPF0473 family
AWV81_13930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWV81_13935	COG4472	Bacterial protein of unknown function (DUF965)
AWV81_13940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWV81_13945	COG0628	permease
AWV81_13950	COG1126	abc transporter atp-binding protein
AWV81_13955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_13960	COG0765	amino acid transport
AWV81_13965	COG0765	amino acid transport
AWV81_13980	COG3881	PFAM PRC-barrel domain
AWV81_13985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWV81_13990	COG0457	Tetratricopeptide repeat
AWV81_13995	COG0482	sulfurtransferase activity
AWV81_14000	COG1104	cysteine desulfurase activity
AWV81_14005	COG1959	2 iron, 2 sulfur cluster binding
AWV81_14010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWV81_14015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AWV81_14025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWV81_14030	COG0124	histidyl-tRNA synthetase
AWV81_14040	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_14040	COG4991	sh3 domain protein
AWV81_14040	COG3103	Sh3 type 3 domain protein
AWV81_14045	COG1490	D-aminoacyl-tRNA deacylase activity
AWV81_14050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWV81_14055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWV81_14060	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWV81_14060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWV81_14065	COG5416	Lipopolysaccharide assembly protein A domain
AWV81_14070	COG0490	domain, Protein
AWV81_14075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWV81_14075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWV81_14085	COG2244	polysaccharide biosynthetic process
AWV81_14090	COG2323	membrane
AWV81_14100	COG1862	Preprotein translocase
AWV81_14105	COG0343	queuine tRNA-ribosyltransferase activity
AWV81_14110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWV81_14120	COG2255	four-way junction helicase activity
AWV81_14125	COG0632	four-way junction helicase activity
AWV81_14135	COG2814	Major facilitator Superfamily
AWV81_14140	COG0673	inositol 2-dehydrogenase activity
AWV81_14145	COG2112	serine threonine protein kinase
AWV81_14165	COG1115	amino acid carrier protein
AWV81_14170	COG0217	transcriptional regulatory protein
AWV81_14180	COG1388	LysM domain
AWV81_14185	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWV81_14190	COG0157	Belongs to the NadC ModD family
AWV81_14195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWV81_14200	COG1104	cysteine desulfurase activity
AWV81_14205	COG1827	regulation of RNA biosynthetic process
AWV81_14210	COG0077	Prephenate dehydratase
AWV81_14215	COG4492	Belongs to the UPF0735 family
AWV81_14220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWV81_14225	COG3290	protein histidine kinase activity
AWV81_14235	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWV81_14240	COG2868	ribosomal protein
AWV81_14245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWV81_14250	COG1994	Peptidase M50
AWV81_14255	COG0739	heme binding
AWV81_14260	COG2894	cell division
AWV81_14265	COG0850	regulation of cytokinetic process
AWV81_14270	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AWV81_14275	COG1792	Involved in formation and maintenance of cell shape
AWV81_14280	COG1077	Cell shape determining protein MreB Mrl
AWV81_14285	COG2003	Belongs to the UPF0758 family
AWV81_14290	COG0424	maF-like protein
AWV81_14300	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWV81_14305	COG0285	dihydrofolate synthase activity
AWV81_14310	COG0525	valine-tRNA ligase activity
AWV81_14320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_14325	COG1388	LysM domain
AWV81_14330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWV81_14335	COG0113	porphobilinogen synthase activity
AWV81_14340	COG1587	Uroporphyrinogen-III synthase
AWV81_14345	COG0181	hydroxymethylbilane synthase activity
AWV81_14350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWV81_14355	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWV81_14365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWV81_14370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWV81_14375	COG1067	ATP-dependent peptidase activity
AWV81_14375	COG0470	DNA polymerase III
AWV81_14380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWV81_14385	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWV81_14390	COG0457	Tetratricopeptide repeat
AWV81_14390	COG1477	protein flavinylation
AWV81_14395	COG0066	3-isopropylmalate dehydratase activity
AWV81_14400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWV81_14405	COG0473	3-isopropylmalate dehydrogenase activity
AWV81_14410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWV81_14415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWV81_14420	COG0440	acetolactate synthase activity
AWV81_14425	COG0028	Belongs to the TPP enzyme family
AWV81_14445	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AWV81_14455	COG2801	Transposase and inactivated derivatives
AWV81_14480	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AWV81_14505	COG0622	Phosphoesterase
AWV81_14510	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWV81_14515	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AWV81_14520	COG5401	PFAM Sporulation and spore germination
AWV81_14525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWV81_14530	COG1846	Transcriptional regulator
AWV81_14535	COG2197	response regulator
AWV81_14540	COG0824	Thioesterase
AWV81_14545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWV81_14550	COG1053	succinate dehydrogenase
AWV81_14555	COG2009	succinate dehydrogenase
AWV81_14565	COG1719	4-vinyl reductase, 4VR
AWV81_14570	COG0527	aspartate kinase activity
AWV81_14575	COG0322	excinuclease ABC activity
AWV81_14580	COG3118	belongs to the thioredoxin family
AWV81_14585	COG3534	alpha-L-arabinofuranosidase
AWV81_14590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AWV81_14595	COG2086	electron transfer activity
AWV81_14600	COG1024	Enoyl-CoA hydratase
AWV81_14605	COG1309	transcriptional regulator
AWV81_14610	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_14615	COG3766	membrane
AWV81_14620	COG1193	negative regulation of DNA recombination
AWV81_14625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWV81_14625	COG1796	DNA polymerase
AWV81_14630	COG1286	toxin biosynthetic process
AWV81_14635	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AWV81_14640	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWV81_14645	COG0072	phenylalanine-tRNA ligase activity
AWV81_14645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_14650	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWV81_14660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWV81_14670	COG3835	regulator
AWV81_14675	COG0277	FAD linked oxidase domain protein
AWV81_14680	COG0247	lactate metabolic process
AWV81_14685	COG0346	lactoylglutathione lyase activity
AWV81_14690	COG1966	Carbon starvation protein
AWV81_14695	COG3534	alpha-L-arabinofuranosidase
AWV81_14700	COG0395	ABC-type sugar transport system, permease component
AWV81_14705	COG1175	transmembrane transport
AWV81_14710	COG1653	transport
AWV81_14715	COG0371	Dehydrogenase
AWV81_14720	COG0647	UMP catabolic process
AWV81_14725	COG0235	Class ii aldolase
AWV81_14730	COG1069	ribulokinase activity
AWV81_14735	COG2160	L-arabinose isomerase activity
AWV81_14745	COG1363	Peptidase, m42
AWV81_14755	COG3326	Membrane
AWV81_14760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWV81_14765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWV81_14770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWV81_14780	COG1346	cytolysis
AWV81_14785	COG1380	Effector of murein hydrolase LrgA
AWV81_14790	COG3279	Response regulator of the LytR AlgR family
AWV81_14795	COG3275	phosphorelay sensor kinase activity
AWV81_14805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWV81_14815	COG0398	Pfam SNARE associated Golgi protein
AWV81_14820	COG1484	DNA-dependent DNA replication
AWV81_14825	COG3611	Membrane attachment protein
AWV81_14830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWV81_14835	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWV81_14840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWV81_14845	COG1733	regulation of RNA biosynthetic process
AWV81_14850	COG2814	Major facilitator Superfamily
AWV81_14855	COG0656	L-ascorbic acid biosynthetic process
AWV81_14860	COG0237	dephospho-CoA kinase activity
AWV81_14875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWV81_14880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWV81_14880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWV81_14885	COG5002	protein histidine kinase activity
AWV81_14890	COG0745	RESPONSE REGULATOR receiver
AWV81_14895	COG0039	L-malate dehydrogenase activity
AWV81_14900	COG0538	isocitrate dehydrogenase activity
AWV81_14905	COG0372	Belongs to the citrate synthase family
AWV81_14910	COG2707	UPF0756 membrane protein
AWV81_14915	COG0628	permease
AWV81_14920	COG3030	protein affecting phage T7 exclusion by the F plasmid
AWV81_14925	COG0469	pyruvate kinase activity
AWV81_14930	COG0205	6-phosphofructokinase activity
AWV81_14935	COG0825	malonyl-CoA metabolic process
AWV81_14940	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWV81_14945	COG0281	malic enzyme
AWV81_14950	COG0587	DNA-directed DNA polymerase activity
AWV81_14970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AWV81_14980	COG4109	DRTGG domain
AWV81_14990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWV81_14995	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_15005	COG0165	Argininosuccinate lyase
AWV81_15010	COG0137	argininosuccinate synthase activity
AWV81_15015	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWV81_15020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AWV81_15030	COG0827	DNA restriction-modification system
AWV81_15035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AWV81_15040	COG3874	Sporulation protein YtfJ
AWV81_15050	COG1714	RDD family
AWV81_15055	COG0616	signal peptide processing
AWV81_15060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWV81_15065	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AWV81_15070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWV81_15080	COG0301	tRNA thio-modification
AWV81_15085	COG1104	cysteine desulfurase activity
AWV81_15090	COG1114	Component of the transport system for branched-chain amino acids
AWV81_15095	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AWV81_15100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AWV81_15105	COG1309	transcriptional regulator
AWV81_15110	COG1956	GAF domain-containing protein
AWV81_15115	COG2203	Gaf domain
AWV81_15115	COG2199	diguanylate cyclase activity
AWV81_15120	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWV81_15130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWV81_15135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWV81_15140	COG0454	-acetyltransferase
AWV81_15145	COG0517	IMP dehydrogenase activity
AWV81_15150	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWV81_15155	COG1360	Flagellar Motor Protein
AWV81_15160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AWV81_15165	COG1609	Transcriptional regulator
AWV81_15170	COG1605	Chorismate mutase
AWV81_15170	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWV81_15175	COG3118	belongs to the thioredoxin family
AWV81_15180	COG4980	gas vesicle protein
AWV81_15185	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AWV81_15190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWV81_15195	COG1674	ftsk spoiiie
AWV81_15200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWV81_15205	COG4848	Belongs to the UPF0354 family
AWV81_15210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_15220	COG1363	Peptidase, m42
AWV81_15225	COG5584	Small secreted protein
AWV81_15230	COG0281	malic enzyme
AWV81_15235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWV81_15240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWV81_15250	COG0510	thiamine kinase activity
AWV81_15255	COG1523	belongs to the glycosyl hydrolase 13 family
AWV81_15260	COG1597	lipid kinase activity
AWV81_15270	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AWV81_15275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWV81_15280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_15285	COG2252	PERMEase
AWV81_15290	COG4473	ABC transporter
AWV81_15295	COG1131	(ABC) transporter
AWV81_15300	COG1349	DNA-binding transcription factor activity
AWV81_15305	COG1187	pseudouridine synthase activity
AWV81_15310	COG2244	polysaccharide biosynthetic process
AWV81_15315	COG2081	HI0933 family
AWV81_15320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AWV81_15340	COG1653	transport
AWV81_15345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWV81_15350	COG4209	transmembrane transport
AWV81_15360	COG1653	transport
AWV81_15365	COG0395	ABC-type sugar transport system, permease component
AWV81_15370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWV81_15375	COG2124	cytochrome p450
AWV81_15395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWV81_15400	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AWV81_15405	COG1073	alpha beta
AWV81_15430	COG1486	melibiose metabolic process
AWV81_15435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWV81_15440	COG0495	leucyl-tRNA aminoacylation
AWV81_15450	COG2202	Pas domain
AWV81_15450	COG1366	Belongs to the anti-sigma-factor antagonist family
AWV81_15455	COG2814	Major facilitator Superfamily
AWV81_15460	COG2433	Pfam Transposase IS66
AWV81_15465	COG0577	efflux transmembrane transporter activity
AWV81_15470	COG1136	(ABC) transporter
AWV81_15475	COG2205	protein histidine kinase activity
AWV81_15480	COG0745	RESPONSE REGULATOR receiver
AWV81_15485	COG0577	efflux transmembrane transporter activity
AWV81_15490	COG1136	(ABC) transporter
AWV81_15505	COG1131	(ABC) transporter
AWV81_15510	COG1725	Transcriptional regulator
AWV81_15525	COG1242	4 iron, 4 sulfur cluster binding
AWV81_15530	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AWV81_15540	COG2267	carboxylic ester hydrolase activity
AWV81_15545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWV81_15550	COG1113	amino acid transport
AWV81_15555	COG0367	asparagine synthase
AWV81_15560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWV81_15565	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AWV81_15575	COG1506	peptidase
AWV81_15580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWV81_15585	COG1116	anion transmembrane transporter activity
AWV81_15590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWV81_15595	COG0494	nUDIX hydrolase
AWV81_15600	COG4824	toxin secretion phage lysis holin
AWV81_15605	COG0783	Belongs to the Dps family
AWV81_15620	COG1854	S-ribosylhomocysteine lyase activity
AWV81_15625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWV81_15630	COG0288	reversible hydration of carbon dioxide
AWV81_15635	COG0254	rRNA binding
AWV81_15640	COG1271	oxidase subunit
AWV81_15645	COG1294	oxidase, subunit
AWV81_15655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWV81_15660	COG1321	iron dependent repressor
AWV81_15660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWV81_15665	COG1121	(ABC) transporter
AWV81_15670	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWV81_15675	COG4948	Mandelate Racemase Muconate Lactonizing
AWV81_15680	COG0318	PFAM AMP-dependent synthetase and ligase
AWV81_15685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AWV81_15690	COG0596	Alpha beta hydrolase
AWV81_15695	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AWV81_15700	COG1169	isochorismate synthase
AWV81_15705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AWV81_15710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWV81_15715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWV81_15720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWV81_15725	COG0438	transferase activity, transferring glycosyl groups
AWV81_15735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_15740	COG0438	transferase activity, transferring glycosyl groups
AWV81_15745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_15750	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AWV81_15755	COG0058	SHG alpha-glucan phosphorylase activity
AWV81_15760	COG0297	glycogen (starch) synthase activity
AWV81_15765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWV81_15770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWV81_15775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWV81_15905	COG3859	Proton-coupled thiamine transporter YuaJ
AWV81_15910	COG1247	-acetyltransferase
AWV81_15915	COG2268	Band 7 protein
AWV81_15920	COG1585	Membrane protein implicated in regulation of membrane protease activity
AWV81_15925	COG2318	DinB family
AWV81_15935	COG1454	alcohol dehydrogenase
AWV81_15945	COG1510	regulation of RNA biosynthetic process
AWV81_15955	COG0569	domain protein
AWV81_15960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWV81_15965	COG4682	membrane
AWV81_15970	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWV81_15975	COG0477	Major facilitator Superfamily
AWV81_15980	COG5553	Cysteine dioxygenase type I
AWV81_15990	COG1968	undecaprenyl-diphosphatase activity
AWV81_15995	COG0628	permease
AWV81_16000	COG0673	inositol 2-dehydrogenase activity
AWV81_16005	COG4806	L-rhamnose isomerase
AWV81_16010	COG3254	rhamnose metabolic process
AWV81_16015	COG1070	Carbohydrate kinase
AWV81_16020	COG1349	DNA-binding transcription factor activity
AWV81_16025	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_16025	COG3347	Dehydrogenase
AWV81_16040	COG0840	transmembrane signaling receptor activity
AWV81_16050	COG0840	transmembrane signaling receptor activity
AWV81_16065	COG0432	Pfam Uncharacterised protein family UPF0047
AWV81_16070	COG0366	Alpha amylase catalytic
AWV81_16075	COG1253	flavin adenine dinucleotide binding
AWV81_16080	COG2738	Putative neutral zinc metallopeptidase
AWV81_16095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AWV81_16110	COG0166	Belongs to the GPI family
AWV81_16115	COG1979	alcohol dehydrogenase
AWV81_16120	COG1979	alcohol dehydrogenase
AWV81_16125	COG2155	Conserved Protein
AWV81_16130	COG1098	S1 RNA binding domain
AWV81_16135	COG0436	Aminotransferase
AWV81_16140	COG1522	sequence-specific DNA binding
AWV81_16145	COG2267	carboxylic ester hydrolase activity
AWV81_16155	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AWV81_16160	COG2205	protein histidine kinase activity
AWV81_16170	COG5018	Exonuclease
AWV81_16180	COG2814	Major facilitator Superfamily
AWV81_16185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_16190	COG3011	Protein conserved in bacteria
AWV81_16200	COG3290	protein histidine kinase activity
AWV81_16205	COG4565	transcriptional regulatory protein
AWV81_16230	COG3493	citrate carrier protein
AWV81_16240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWV81_16240	COG2111	Na H antiporter
AWV81_16245	COG2111	Na H antiporter
AWV81_16250	COG1006	Multisubunit Na H antiporter MnhC subunit
AWV81_16255	COG0651	ATP synthesis coupled electron transport
AWV81_16260	COG1863	multisubunit Na H antiporter MnhE subunit
AWV81_16265	COG2212	antiporter activity
AWV81_16270	COG1320	monovalent cation:proton antiporter activity
AWV81_16275	COG2050	protein possibly involved in aromatic compounds catabolism
AWV81_16280	COG2197	response regulator
AWV81_16285	COG4585	Histidine kinase
AWV81_16295	COG0142	geranyltranstransferase activity
AWV81_16310	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AWV81_16315	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWV81_16320	COG1335	isochorismatase
AWV81_16325	COG5506	Protein of unknown function (DUF1694)
AWV81_16340	COG0628	permease
AWV81_16355	COG1418	mRNA catabolic process
AWV81_16360	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_16370	COG1511	domain protein
AWV81_16375	COG0433	COG0433 Predicted ATPase
AWV81_16375	COG1674	ftsk spoiiie
AWV81_16380	COG4499	WXG100 protein secretion system (Wss), protein YukC
AWV81_16385	COG5417	Belongs to the EsaB family
AWV81_16390	COG4842	Belongs to the WXG100 family
AWV81_16395	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AWV81_16395	COG2508	Transcriptional regulator
AWV81_16400	COG0686	Belongs to the AlaDH PNT family
AWV81_16405	COG5634	Uncharacterized conserved protein (DUF2278)
AWV81_16410	COG3251	PFAM MbtH domain protein
AWV81_16415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_16420	COG3433	isochorismatase activity
AWV81_16420	COG1535	isochorismatase
AWV81_16425	COG1021	2,3-dihydroxybenzoate-AMP ligase
AWV81_16430	COG1169	isochorismate synthase
AWV81_16435	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_16440	COG2819	hydrolase of the alpha beta superfamily
AWV81_16445	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AWV81_16450	COG1268	BioY protein
AWV81_16455	COG2056	Na+-H+ antiporter family
AWV81_16460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWV81_16465	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AWV81_16470	COG3584	3D domain protein
AWV81_16485	COG1252	NADH dehydrogenase
AWV81_16490	COG0492	ferredoxin-NADP+ reductase activity
AWV81_16500	COG0516	GMP reductase activity
AWV81_16505	COG2808	Putative FMN-binding domain
AWV81_16510	COG0456	acetyltransferase
AWV81_16605	COG0582	viral genome integration into host DNA
AWV81_16615	COG4974	Belongs to the 'phage' integrase family
AWV81_16620	COG0316	Belongs to the HesB IscA family
AWV81_16625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWV81_16630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWV81_16635	COG4844	belongs to the
AWV81_16640	COG1252	NADH dehydrogenase
AWV81_16645	COG4837	Protein of unknown function (DUF1462)
AWV81_16650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWV81_16655	COG0823	Involved in the tonB-independent uptake of proteins
AWV81_16655	COG4946	Tricorn protease homolog
AWV81_16655	COG1506	peptidase
AWV81_16660	COG0083	homoserine kinase activity
AWV81_16665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWV81_16670	COG0460	homoserine dehydrogenase
AWV81_16675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWV81_16680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWV81_16685	COG0647	UMP catabolic process
AWV81_16690	COG2445	Protein of unknown function DUF86
AWV81_16695	COG4470	Protein conserved in bacteria
AWV81_16705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWV81_16710	COG0739	heme binding
AWV81_16720	COG3377	Domain of unknown function (DUF1805)
AWV81_16725	COG0737	Belongs to the 5'-nucleotidase family
AWV81_16730	COG0730	response to heat
AWV81_16735	COG1801	Protein of unknown function DUF72
AWV81_16745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWV81_16750	COG2508	Transcriptional regulator
AWV81_16755	COG2233	PERMEase
AWV81_16760	COG2233	PERMEase
AWV81_16765	COG3648	Uricase
AWV81_16765	COG3195	allantoin biosynthetic process
AWV81_16770	COG2351	hydroxyisourate hydrolase activity
AWV81_16780	COG2080	2 iron, 2 sulfur cluster binding
AWV81_16785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AWV81_16790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AWV81_16795	COG2068	MobA-Related Protein
AWV81_16800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AWV81_16805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWV81_16810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWV81_16820	COG2356	endonuclease I
AWV81_16825	COG3842	ATPase activity
AWV81_16830	COG2188	Transcriptional regulator
AWV81_16835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_16845	COG1175	transmembrane transport
AWV81_16850	COG1653	transport
AWV81_16855	COG2222	sugar isomerase
AWV81_16860	COG0322	excinuclease ABC activity
AWV81_16865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWV81_16880	COG0346	lactoylglutathione lyase activity
AWV81_16885	COG0640	Transcriptional regulator
AWV81_16890	COG0719	Fe-S assembly protein
AWV81_16895	COG0822	iron-sulfur transferase activity
AWV81_16900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWV81_16905	COG0719	Fe-S assembly protein
AWV81_16910	COG0396	ATPase activity
AWV81_16925	COG1464	Belongs to the NlpA lipoprotein family
AWV81_16930	COG2011	ABC-type metal ion transport system permease component
AWV81_16935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWV81_16945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWV81_16950	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AWV81_16960	COG0509	glycine decarboxylation via glycine cleavage system
AWV81_16965	COG1393	Belongs to the ArsC family
AWV81_16970	COG1960	acyl-CoA dehydrogenase activity
AWV81_16975	COG0183	Belongs to the thiolase family
AWV81_16980	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWV81_16980	COG1024	Enoyl-CoA hydratase
AWV81_17000	COG5577	PFAM Coat F domain
AWV81_17005	COG1846	Transcriptional regulator
AWV81_17010	COG0477	Major facilitator Superfamily
AWV81_17015	COG1942	4-Oxalocrotonate Tautomerase
AWV81_17020	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_17025	COG0583	DNA-binding transcription factor activity
AWV81_17035	COG1120	ATPase activity
AWV81_17055	COG1131	(ABC) transporter
AWV81_17105	COG0783	Belongs to the Dps family
AWV81_17110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_17115	COG0745	RESPONSE REGULATOR receiver
AWV81_17120	COG2205	protein histidine kinase activity
AWV81_17120	COG2770	Histidine kinase
AWV81_17130	COG1309	transcriptional regulator
AWV81_17135	COG0114	fumarate hydratase activity
AWV81_17145	COG0697	spore germination
AWV81_17150	COG0814	amino acid
AWV81_17160	COG2197	response regulator
AWV81_17165	COG4585	Histidine kinase
AWV81_17170	COG4758	membrane
AWV81_17175	COG3595	metallopeptidase activity
AWV81_17180	COG1842	Phage shock protein A
AWV81_17185	COG4758	membrane
AWV81_17190	COG2814	Major facilitator Superfamily
AWV81_17195	COG2096	Adenosyltransferase
AWV81_17200	COG1120	ATPase activity
AWV81_17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_17210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_17215	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_17220	COG3386	PFAM SMP-30 Gluconolaconase
AWV81_17225	COG2205	protein histidine kinase activity
AWV81_17230	COG0745	RESPONSE REGULATOR receiver
AWV81_17250	COG2140	Oxalate decarboxylase
AWV81_17260	COG0577	efflux transmembrane transporter activity
AWV81_17265	COG1136	(ABC) transporter
AWV81_17270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWV81_17275	COG1120	ATPase activity
AWV81_17280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_17285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWV81_17290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_17300	COG0531	amino acid
AWV81_17310	COG1988	membrane-bound metal-dependent
AWV81_17315	COG1368	sulfuric ester hydrolase activity
AWV81_17320	COG1910	domain protein
AWV81_17325	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWV81_17330	COG4149	molybdate abc transporter
AWV81_17335	COG0656	L-ascorbic acid biosynthetic process
AWV81_17345	COG0025	NhaP-type Na H and K H
AWV81_17350	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AWV81_17355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWV81_17360	COG3973	AAA domain
AWV81_17370	COG2860	membrane
AWV81_17375	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AWV81_17380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWV81_17385	COG2217	Heavy metal translocating P-type atpase
AWV81_17390	COG2217	Heavy metal translocating P-type atpase
AWV81_17395	COG2608	mercury ion transmembrane transporter activity
AWV81_17400	COG1937	Protein conserved in bacteria
AWV81_17405	COG0673	inositol 2-dehydrogenase activity
AWV81_17415	COG1289	transmembrane transporter activity
AWV81_17425	COG2076	Multidrug Resistance protein
AWV81_17430	COG1309	transcriptional regulator
AWV81_17435	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_17445	COG5444	nuclease activity
AWV81_17460	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_17460	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_17465	COG4824	toxin secretion phage lysis holin
AWV81_17485	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWV81_17485	COG3942	CHAP domain
AWV81_17705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AWV81_17710	COG0557	exoribonuclease II activity
AWV81_17715	COG1647	Serine aminopeptidase, S33
AWV81_17720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWV81_17725	COG0596	Alpha beta hydrolase
AWV81_17730	COG1476	TRANSCRIPTIONal
AWV81_17735	COG1396	sequence-specific DNA binding
AWV81_17740	COG1396	sequence-specific DNA binding
AWV81_17745	COG1733	regulation of RNA biosynthetic process
AWV81_17750	COG0840	transmembrane signaling receptor activity
AWV81_17755	COG1174	glycine betaine transport
AWV81_17760	COG1732	Glycine betaine
AWV81_17765	COG1174	glycine betaine transport
AWV81_17770	COG0517	IMP dehydrogenase activity
AWV81_17770	COG1125	glycine betaine transport
AWV81_17775	COG1510	regulation of RNA biosynthetic process
AWV81_17780	COG1174	glycine betaine transport
AWV81_17785	COG1732	Glycine betaine
AWV81_17790	COG1174	glycine betaine transport
AWV81_17795	COG1125	glycine betaine transport
AWV81_17795	COG0517	IMP dehydrogenase activity
AWV81_17800	COG1510	regulation of RNA biosynthetic process
AWV81_17805	COG2095	MarC family integral membrane protein
AWV81_17815	COG3064	Membrane
AWV81_17820	COG4640	response to antibiotic
AWV81_17825	COG0456	acetyltransferase
AWV81_17830	COG0148	phosphopyruvate hydratase activity
AWV81_17835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWV81_17840	COG0149	triose-phosphate isomerase activity
AWV81_17845	COG0126	phosphoglycerate kinase activity
AWV81_17855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWV81_17860	COG2390	Transcriptional regulator
AWV81_17865	COG2814	Major facilitator Superfamily
AWV81_17870	COG1609	Transcriptional regulator
AWV81_17875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWV81_17880	COG0583	DNA-binding transcription factor activity
AWV81_17885	COG0697	spore germination
AWV81_17890	COG1113	amino acid transport
AWV81_17900	COG1556	Lactate utilization protein
AWV81_17905	COG1139	Iron-sulfur cluster binding protein
AWV81_17910	COG0247	lactate metabolic process
AWV81_17915	COG2197	response regulator
AWV81_17920	COG4585	Histidine kinase
AWV81_17925	COG0842	Transport permease protein
AWV81_17930	COG1131	(ABC) transporter
AWV81_17950	COG0596	Alpha beta hydrolase
AWV81_17955	COG2208	phosphoserine phosphatase activity
AWV81_17960	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AWV81_17965	COG1874	Beta-galactosidase
AWV81_17970	COG3833	ABC-type maltose transport systems, permease component
AWV81_17975	COG1175	transmembrane transport
AWV81_17980	COG2182	Extracellular solute-binding protein
AWV81_17985	COG1609	Transcriptional regulator
AWV81_17990	COG2186	Transcriptional regulator
AWV81_17995	COG1620	l-lactate permease
AWV81_18000	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AWV81_18010	COG5039	Polysaccharide pyruvyl transferase
AWV81_18015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWV81_18020	COG0110	maltose O-acetyltransferase activity
AWV81_18025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWV81_18030	COG2244	polysaccharide biosynthetic process
AWV81_18035	COG1216	Glycosyl transferase, family 2
AWV81_18040	COG5039	Polysaccharide pyruvyl transferase
AWV81_18045	COG1216	Glycosyl transferase, family 2
AWV81_18055	COG0438	transferase activity, transferring glycosyl groups
AWV81_18060	COG1215	transferase activity, transferring glycosyl groups
AWV81_18065	COG0438	transferase activity, transferring glycosyl groups
AWV81_18070	COG1086	Polysaccharide biosynthesis protein
AWV81_18075	COG0489	protein tyrosine kinase activity
AWV81_18080	COG3944	biosynthesis protein
AWV81_18085	COG1396	sequence-specific DNA binding
AWV81_18090	COG2272	Belongs to the type-B carboxylesterase lipase family
AWV81_18100	COG3479	Phenolic acid decarboxylase
AWV81_18110	COG1794	racemase activity, acting on amino acids and derivatives
AWV81_18120	COG1621	beta-fructofuranosidase activity
AWV81_18125	COG1621	beta-fructofuranosidase activity
AWV81_18130	COG0531	amino acid
AWV81_18135	COG1309	transcriptional regulator
AWV81_18140	COG2076	Multidrug Resistance protein
AWV81_18145	COG2076	Multidrug Resistance protein
AWV81_18165	COG1674	ftsk spoiiie
AWV81_18185	COG5632	N-Acetylmuramoyl-L-alanine amidase
AWV81_18185	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_18185	COG1388	LysM domain
AWV81_18220	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWV81_18300	COG0582	viral genome integration into host DNA
AWV81_18400	COG4974	Belongs to the 'phage' integrase family
AWV81_18410	COG0740	serine-type endopeptidase activity
AWV81_18415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWV81_18420	COG0366	Alpha amylase catalytic
AWV81_18425	COG1554	hydrolase, family 65, central catalytic
AWV81_18430	COG5521	maltodextrose utilization protein MalA
AWV81_18435	COG3833	ABC-type maltose transport systems, permease component
AWV81_18440	COG1175	transmembrane transport
AWV81_18445	COG2182	Extracellular solute-binding protein
AWV81_18455	COG1609	Transcriptional regulator
AWV81_18460	COG1611	Belongs to the LOG family
AWV81_18470	COG0659	secondary active sulfate transmembrane transporter activity
AWV81_18475	COG0288	reversible hydration of carbon dioxide
AWV81_18480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWV81_18485	COG0577	efflux transmembrane transporter activity
AWV81_18490	COG1136	(ABC) transporter
AWV81_18495	COG5002	protein histidine kinase activity
AWV81_18500	COG0745	RESPONSE REGULATOR receiver
AWV81_18510	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AWV81_18515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_18520	COG1481	regulation of sporulation
AWV81_18525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWV81_18530	COG1660	Displays ATPase and GTPase activities
AWV81_18535	COG1051	belongs to the nudix hydrolase family
AWV81_18540	COG0492	ferredoxin-NADP+ reductase activity
AWV81_18545	COG0791	NLP P60 protein
AWV81_18545	COG3883	PFAM NLP P60 protein
AWV81_18550	COG0457	Tetratricopeptide repeat
AWV81_18555	COG1132	(ABC) transporter
AWV81_18575	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWV81_18575	COG0140	phosphoribosyl-ATP diphosphatase activity
AWV81_18580	COG0107	imidazoleglycerol-phosphate synthase activity
AWV81_18585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWV81_18590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AWV81_18595	COG0131	Imidazoleglycerol-phosphate dehydratase
AWV81_18600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWV81_18605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWV81_18610	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWV81_18615	COG4990	cell redox homeostasis
AWV81_18620	COG5297	Belongs to the glycosyl hydrolase family 6
AWV81_18630	COG2801	Transposase and inactivated derivatives
AWV81_18640	COG0546	phosphoglycolate phosphatase activity
AWV81_18645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AWV81_18650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWV81_18655	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AWV81_18660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWV81_18665	COG0363	glucosamine-6-phosphate deaminase activity
AWV81_18675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AWV81_18690	COG1950	PFAM Membrane protein of
AWV81_18695	COG1983	PspC domain protein
AWV81_18700	COG3595	metallopeptidase activity
AWV81_18715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWV81_18720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWV81_18725	COG0556	nucleotide-excision repair
AWV81_18730	COG4897	Protein conserved in bacteria
AWV81_18735	COG0574	Belongs to the PEP-utilizing enzyme family
AWV81_18735	COG3848	Pyruvate phosphate dikinase
AWV81_18740	COG1309	transcriptional regulator
AWV81_18745	COG2814	Major facilitator Superfamily
AWV81_18750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_18760	COG0793	Belongs to the peptidase S41A family
AWV81_18760	COG3409	Peptidoglycan-binding domain 1 protein
AWV81_18765	COG2177	Part of the ABC transporter FtsEX involved in
AWV81_18770	COG2884	Cell division ATP-binding protein ftsE
AWV81_18775	COG2010	Cytochrome c
AWV81_18780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_18785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AWV81_18790	COG0653	protein targeting
AWV81_18795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWV81_18810	COG1516	flagellar protein fliS
AWV81_18815	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AWV81_18820	COG1334	flagellar protein FlaG
AWV81_18825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWV81_18830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AWV81_18835	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AWV81_18845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AWV81_18850	COG4786	Flagellar basal body rod
AWV81_18850	COG1256	bacterial-type flagellum assembly
AWV81_18855	COG3418	PFAM FlgN family protein
AWV81_18860	COG2747	anti-sigma28 factor FlgM
AWV81_18870	COG1040	competence protein
AWV81_18880	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AWV81_18885	COG1307	EDD domain protein, DegV family
AWV81_18890	COG2197	response regulator
AWV81_18895	COG4585	Histidine kinase
AWV81_18900	COG1739	Uncharacterized protein family UPF0029
AWV81_18905	COG1316	TRANSCRIPTIONal
AWV81_18940	COG1131	(ABC) transporter
AWV81_18950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWV81_18955	COG0438	transferase activity, transferring glycosyl groups
AWV81_18960	COG1215	transferase activity, transferring glycosyl groups
AWV81_18965	COG3206	protein involved in exopolysaccharide biosynthesis
AWV81_18970	COG3307	-O-antigen
AWV81_18975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWV81_18980	COG0297	glycogen (starch) synthase activity
AWV81_18980	COG0438	transferase activity, transferring glycosyl groups
AWV81_18985	COG2244	polysaccharide biosynthetic process
AWV81_19000	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWV81_19000	COG2247	cell wall binding repeat
AWV81_19005	COG2247	cell wall binding repeat
AWV81_19005	COG2385	sporulation resulting in formation of a cellular spore
AWV81_19035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWV81_19040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AWV81_19050	COG1134	teichoic acid transport
AWV81_19055	COG1682	transport, permease protein
AWV81_19070	COG0463	Glycosyl transferase, family 2
AWV81_19070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_19075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_19080	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AWV81_19085	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AWV81_19090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_19095	COG4193	domain, Protein
AWV81_19100	COG1482	cell wall glycoprotein biosynthetic process
AWV81_19110	COG0697	spore germination
AWV81_19115	COG0814	amino acid
AWV81_19130	COG1316	TRANSCRIPTIONal
AWV81_19135	COG0561	phosphatase activity
AWV81_19140	COG0791	NLP P60 protein
AWV81_19150	COG2843	Capsule synthesis protein
AWV81_19160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWV81_19165	COG1609	Transcriptional regulator
AWV81_19170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_19175	COG1869	D-ribose catabolic process
AWV81_19180	COG1129	ABC transporter
AWV81_19185	COG1172	Belongs to the binding-protein-dependent transport system permease family
AWV81_19190	COG1879	ABC-type sugar transport system periplasmic component
AWV81_19195	COG3103	Sh3 type 3 domain protein
AWV81_19205	COG2249	NAD(P)H dehydrogenase (quinone) activity
AWV81_19210	COG3527	Alpha-acetolactate decarboxylase
AWV81_19215	COG0028	Belongs to the TPP enzyme family
AWV81_19220	COG0583	DNA-binding transcription factor activity
AWV81_19225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AWV81_19240	COG5337	Spore coat protein CotH
AWV81_19250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWV81_19260	COG0405	Gamma-glutamyltransferase
AWV81_19265	COG1522	sequence-specific DNA binding
AWV81_19270	COG2059	Chromate
AWV81_19275	COG2059	Chromate
AWV81_19285	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWV81_19290	COG0583	DNA-binding transcription factor activity
AWV81_19320	COG5444	nuclease activity
AWV81_19340	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWV81_19345	COG4464	protein tyrosine phosphatase activity
AWV81_19350	COG0489	protein tyrosine kinase activity
AWV81_19355	COG3944	biosynthesis protein
AWV81_19365	COG4715	Zinc finger, swim domain protein
AWV81_19370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWV81_19375	COG0561	phosphatase activity
AWV81_19380	COG1349	DNA-binding transcription factor activity
AWV81_19385	COG0629	single-stranded DNA binding
AWV81_19400	COG3764	Sortase (surface protein transpeptidase)
AWV81_19405	COG2972	Histidine kinase
AWV81_19405	COG0745	RESPONSE REGULATOR receiver
AWV81_19410	COG1970	mechanosensitive ion channel activity
AWV81_19415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWV81_19420	COG0457	Tetratricopeptide repeat
AWV81_19425	COG4786	Flagellar basal body rod
AWV81_19430	COG4786	Flagellar basal body rod
AWV81_19435	COG1077	Cell shape determining protein MreB Mrl
AWV81_19440	COG1609	Transcriptional regulator
AWV81_19445	COG1846	Transcriptional regulator
AWV81_19450	COG2814	Major facilitator Superfamily
AWV81_19455	COG3420	alginic acid biosynthetic process
AWV81_19460	COG1953	Uracil, thiamine, allantoin
AWV81_19465	COG0477	Major facilitator Superfamily
AWV81_19470	COG1335	isochorismatase
AWV81_19480	COG0004	ammonium transporteR
AWV81_19485	COG0347	Belongs to the P(II) protein family
AWV81_19490	COG0671	phosphoesterase, PA-phosphatase related
AWV81_19500	COG0739	heme binding
AWV81_19505	COG1247	-acetyltransferase
AWV81_19515	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AWV81_19525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWV81_19530	COG0789	Transcriptional regulator
AWV81_19540	COG2910	NAD(P)H-binding
AWV81_19545	COG1959	2 iron, 2 sulfur cluster binding
AWV81_19550	COG0804	urea catabolic process
AWV81_19555	COG0832	Belongs to the urease beta subunit family
AWV81_19560	COG0831	urea catabolic process
AWV81_19570	COG3237	CsbD-like
AWV81_19575	COG1994	Peptidase M50
AWV81_19580	COG0457	Tetratricopeptide repeat
AWV81_19585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWV81_19590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AWV81_19600	COG2304	oxidoreductase activity
AWV81_19610	COG2304	oxidoreductase activity
AWV81_19615	COG2385	sporulation resulting in formation of a cellular spore
AWV81_19620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWV81_19630	COG4836	Membrane
AWV81_19640	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWV81_19645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWV81_19650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWV81_19655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWV81_19660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWV81_19665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWV81_19675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWV81_19680	COG0356	it plays a direct role in the translocation of protons across the membrane
AWV81_19690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWV81_19695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWV81_19700	COG4475	Protein of unknown function (DUF436)
AWV81_19705	COG0698	ribose 5-phosphate isomerase
AWV81_19710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWV81_19715	COG1971	Probably functions as a manganese efflux pump
AWV81_19720	COG0009	L-threonylcarbamoyladenylate synthase
AWV81_19725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AWV81_19745	COG2890	protein-(glutamine-N5) methyltransferase activity
AWV81_19750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWV81_19755	COG0346	lactoylglutathione lyase activity
AWV81_19760	COG0789	Transcriptional regulator
AWV81_19765	COG0679	Auxin Efflux Carrier
AWV81_19770	COG0281	malic enzyme
AWV81_19775	COG1435	thymidine kinase activity
AWV81_19780	COG0254	rRNA binding
AWV81_19785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AWV81_19795	COG1494	fructose-1,6-bisphosphatase
AWV81_19800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWV81_19805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWV81_19810	COG0191	fructose-bisphosphate aldolase activity
AWV81_19815	COG2204	response regulator
AWV81_19820	COG4821	SIS domain
AWV81_19825	COG0504	CTP synthase activity
AWV81_19830	COG3343	RNA polymerase activity
AWV81_19835	COG1960	acyl-CoA dehydrogenase activity
AWV81_19840	COG0247	lactate metabolic process
AWV81_19840	COG2181	nitrate reductase activity
AWV81_19845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWV81_19850	COG4294	response to UV
AWV81_19860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWV81_19870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWV81_19875	COG2181	nitrate reductase activity
AWV81_19880	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AWV81_19885	COG1140	nitrate reductase beta subunit
AWV81_19890	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AWV81_19895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWV81_19905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWV81_19910	COG2223	nitrite transmembrane transporter activity
AWV81_19915	COG0018	arginyl-trna synthetase
AWV81_19920	COG4506	Protein conserved in bacteria
AWV81_19930	COG0535	radical SAM domain protein
AWV81_19940	COG1131	(ABC) transporter
AWV81_19945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWV81_19950	COG0612	Peptidase, M16
AWV81_19955	COG0612	Peptidase, M16
AWV81_19965	COG3391	amine dehydrogenase activity
AWV81_19970	COG3391	amine dehydrogenase activity
AWV81_19980	COG0457	Tetratricopeptide repeat
AWV81_19995	COG0010	Belongs to the arginase family
AWV81_20000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWV81_20005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWV81_20020	COG1994	Peptidase M50
AWV81_20025	COG1942	4-Oxalocrotonate Tautomerase
AWV81_20030	COG1846	Transcriptional regulator
AWV81_20035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWV81_20045	COG0477	Major facilitator Superfamily
AWV81_20050	COG1959	2 iron, 2 sulfur cluster binding
AWV81_20055	COG3465	dGTPase activity
AWV81_20060	COG1078	dGTPase activity
AWV81_20065	COG4844	belongs to the
AWV81_20075	COG0697	spore germination
AWV81_20080	COG0095	Lipoate-protein ligase
AWV81_20085	COG0583	DNA-binding transcription factor activity
AWV81_20090	COG0280	phosphate acetyltransferase
AWV81_20100	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_20105	COG0436	Aminotransferase
AWV81_20110	COG2814	Major facilitator Superfamily
AWV81_20115	COG0151	Belongs to the GarS family
AWV81_20120	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_20125	COG1917	Cupin 2, conserved barrel domain protein
AWV81_20130	COG0077	Prephenate dehydratase
AWV81_20135	COG2814	Major facilitator Superfamily
AWV81_20140	COG0833	amino acid
AWV81_20145	COG4187	Peptidase family M20/M25/M40
AWV81_20150	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_20155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWV81_20165	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AWV81_20170	COG1091	dTDP-4-dehydrorhamnose reductase activity
AWV81_20175	COG1088	dTDP-glucose 4,6-dehydratase activity
AWV81_20180	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AWV81_20185	COG3980	spore coat polysaccharide biosynthesis protein
AWV81_20190	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AWV81_20195	COG2089	acid synthase
AWV81_20200	COG0456	acetyltransferase
AWV81_20205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AWV81_20210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AWV81_20215	COG0463	Glycosyl transferase, family 2
AWV81_20230	COG2363	Small membrane protein
AWV81_20235	COG2233	PERMEase
AWV81_20245	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_20250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AWV81_20255	COG1216	Glycosyl transferase, family 2
AWV81_20260	COG0351	phosphomethylpyrimidine kinase
AWV81_20270	COG1621	beta-fructofuranosidase activity
AWV81_20275	COG1263	PTS System
AWV81_20275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_20280	COG2116	formate transmembrane transporter activity
AWV81_20295	COG1404	Belongs to the peptidase S8 family
AWV81_20300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWV81_20305	COG0778	Nitroreductase
AWV81_20310	COG0772	Belongs to the SEDS family
AWV81_20325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AWV81_20330	COG1845	cytochrome c oxidase, subunit III
AWV81_20335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWV81_20340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWV81_20345	COG2261	transglycosylase associated protein
AWV81_20350	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AWV81_20355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AWV81_20360	COG2246	polysaccharide biosynthetic process
AWV81_20365	COG1309	transcriptional regulator
AWV81_20375	COG3162	membrane
AWV81_20380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWV81_20385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AWV81_20390	COG2837	iron assimilation
AWV81_20395	COG2822	iron ion transport
AWV81_20400	COG0672	)-iron permease
AWV81_20405	COG0352	thiamine-phosphate diphosphorylase activity
AWV81_20410	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AWV81_20415	COG0583	DNA-binding transcription factor activity
AWV81_20420	COG1380	Effector of murein hydrolase LrgA
AWV81_20425	COG1346	cytolysis
AWV81_20430	COG2814	Major facilitator Superfamily
AWV81_20435	COG4895	conserved protein (DUF2196)
AWV81_20440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWV81_20445	COG0346	lactoylglutathione lyase activity
AWV81_20460	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_20470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_20470	COG1263	PTS System
AWV81_20475	COG3711	transcriptional antiterminator
AWV81_20480	COG1442	glycosyl transferase family 8
AWV81_20485	COG5522	Integral membrane protein (intg_mem_TP0381)
AWV81_20490	COG1846	Transcriptional regulator
AWV81_20495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWV81_20500	COG2234	aminopeptidase activity
AWV81_20505	COG2357	RelA SpoT domain protein
AWV81_20515	COG2801	Transposase and inactivated derivatives
AWV81_20520	COG1575	Belongs to the MenA family. Type 1 subfamily
AWV81_20535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AWV81_20540	COG1696	Membrane protein involved in D-alanine export
AWV81_20545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWV81_20550	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AWV81_20560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWV81_20565	COG1486	melibiose metabolic process
AWV81_20570	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWV81_20575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_20580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWV81_20585	COG3711	transcriptional antiterminator
AWV81_20585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWV81_20595	COG2094	Belongs to the DNA glycosylase MPG family
AWV81_20600	COG0753	catalase activity
AWV81_20605	COG2814	Major facilitator Superfamily
AWV81_20610	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AWV81_20615	COG1131	(ABC) transporter
AWV81_20635	COG1595	DNA-templated transcription, initiation
AWV81_20640	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AWV81_20645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWV81_20650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AWV81_20655	COG4988	ABC transporter
AWV81_20660	COG1294	oxidase, subunit
AWV81_20665	COG1271	oxidase subunit
AWV81_20670	COG3493	citrate carrier protein
AWV81_20675	COG0501	Belongs to the peptidase M48B family
AWV81_20685	COG0726	polysaccharide deacetylase
AWV81_20690	COG3842	ATPase activity
AWV81_20695	COG2508	Transcriptional regulator
AWV81_20700	COG1012	belongs to the aldehyde dehydrogenase family
AWV81_20705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWV81_20715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWV81_20725	COG4585	Histidine kinase
AWV81_20730	COG2197	response regulator
AWV81_20735	COG2195	Cleaves the N-terminal amino acid of tripeptides
AWV81_20750	COG4894	glucomannan catabolic process
AWV81_20755	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWV81_20760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWV81_20765	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_20770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWV81_20775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWV81_20780	COG2610	gluconate transmembrane transporter activity
AWV81_20790	COG0500	methyltransferase
AWV81_20795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWV81_20810	COG0753	catalase activity
AWV81_20810	COG0693	protein deglycase activity
AWV81_20815	COG2851	Citrate transporter
AWV81_20820	COG2273	Hydrolase Family 16
AWV81_20825	COG3711	transcriptional antiterminator
AWV81_20835	COG2270	Major facilitator Superfamily
AWV81_20840	COG0513	Belongs to the DEAD box helicase family
AWV81_20845	COG2755	lipolytic protein G-D-S-L family
AWV81_20845	COG3401	FG-GAP repeat protein
AWV81_20960	COG0697	spore germination
AWV81_20975	COG0589	response to stress
AWV81_20985	COG2190	(PTS) system
AWV81_20985	COG1263	PTS System
AWV81_20985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWV81_20995	COG5444	nuclease activity
AWV81_21005	COG5444	nuclease activity
AWV81_21025	COG0494	nUDIX hydrolase
AWV81_21030	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AWV81_21035	COG3507	Belongs to the glycosyl hydrolase 43 family
AWV81_21050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AWV81_21055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWV81_21060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWV81_21065	COG2390	Transcriptional regulator
AWV81_21075	COG3192	ethanolamine utilization protein
AWV81_21080	COG2079	MmgE PrpD family protein
AWV81_21090	COG1126	abc transporter atp-binding protein
AWV81_21095	COG0765	amino acid transport
AWV81_21100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWV81_21115	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AWV81_21120	COG0561	phosphatase activity
AWV81_21150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWV81_21155	COG5294	Protein conserved in bacteria
AWV81_21170	COG2205	protein histidine kinase activity
AWV81_21175	COG0745	RESPONSE REGULATOR receiver
AWV81_21180	COG0191	fructose-bisphosphate aldolase activity
AWV81_21185	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_21190	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_21195	COG0673	inositol 2-dehydrogenase activity
AWV81_21200	COG2814	Major facilitator Superfamily
AWV81_21205	COG1082	Xylose isomerase domain protein TIM barrel
AWV81_21210	COG3962	Belongs to the TPP enzyme family
AWV81_21215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWV81_21235	COG1349	DNA-binding transcription factor activity
AWV81_21240	COG0667	Aldo Keto reductase
AWV81_21270	COG0326	Molecular chaperone. Has ATPase activity
AWV81_21325	COG1917	Cupin 2, conserved barrel domain protein
AWV81_21330	COG1309	transcriptional regulator
AWV81_21335	COG1028	Short-chain dehydrogenase reductase Sdr
AWV81_21340	COG1846	Transcriptional regulator
AWV81_21345	COG1380	Effector of murein hydrolase LrgA
AWV81_21350	COG1346	cytolysis
AWV81_21355	COG5039	Polysaccharide pyruvyl transferase
AWV81_21360	COG1929	Belongs to the glycerate kinase type-1 family
AWV81_21365	COG1802	Transcriptional regulator
AWV81_21370	COG1070	Carbohydrate kinase
AWV81_21375	COG2610	gluconate transmembrane transporter activity
AWV81_21380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWV81_21385	COG0450	alkyl hydroperoxide reductase
AWV81_21390	COG3634	alkyl hydroperoxide reductase activity
AWV81_21395	COG2723	6-phospho-beta-galactosidase activity
AWV81_21410	COG2188	Transcriptional regulator
AWV81_21420	COG1131	(ABC) transporter
AWV81_21425	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AWV81_21440	COG0071	Belongs to the small heat shock protein (HSP20) family
AWV81_21470	COG0210	DNA helicase
AWV81_21500	COG2963	transposase activity
AWV81_21535	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AWV81_21545	COG1063	alcohol dehydrogenase
AWV81_21565	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AWV81_21570	COG0456	acetyltransferase
AWV81_21575	COG0457	Tetratricopeptide repeat
AWV81_21585	COG0010	Belongs to the arginase family
AWV81_21590	COG0833	amino acid
AWV81_21595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWV81_21615	COG5658	integral membrane protein
AWV81_21620	COG0640	Transcriptional regulator
AWV81_21625	COG3829	transcription factor binding
AWV81_21635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWV81_21640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWV81_21645	COG4853	Protein conserved in bacteria
AWV81_21650	COG4863	YycH protein
AWV81_21655	COG5002	protein histidine kinase activity
AWV81_21660	COG0745	RESPONSE REGULATOR receiver
AWV81_21690	COG0346	lactoylglutathione lyase activity
AWV81_21695	COG0305	Participates in initiation and elongation during chromosome replication
AWV81_21715	COG3093	addiction module antidote protein HigA
AWV81_21720	COG2807	transmembrane transport
AWV81_21725	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWV81_21730	COG0359	binds to the 23S rRNA
AWV81_21735	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AWV81_21740	COG4241	membrane
AWV81_21755	COG1733	regulation of RNA biosynthetic process
AWV81_21760	COG1227	inorganic diphosphatase activity
AWV81_21775	COG2271	Major facilitator Superfamily
AWV81_21780	COG4978	Transcriptional regulator
AWV81_21780	COG0789	Transcriptional regulator
AWV81_21790	COG4319	ketosteroid isomerase
AWV81_21795	COG1357	PFAM Pentapeptide repeats (8 copies)
AWV81_21810	COG1846	Transcriptional regulator
AWV81_21815	COG2153	protein acetylation
AWV81_21820	COG2364	Membrane
AWV81_21825	COG0456	acetyltransferase
AWV81_21830	COG2315	Protein conserved in bacteria
AWV81_21835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWV81_21840	COG1331	Highly conserved protein containing a thioredoxin domain
AWV81_21845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AWV81_21850	COG1331	Highly conserved protein containing a thioredoxin domain
AWV81_21855	COG1266	CAAX protease self-immunity
AWV81_21860	COG2814	Major facilitator Superfamily
AWV81_21860	COG0477	Major facilitator Superfamily
AWV81_21865	COG0346	lactoylglutathione lyase activity
AWV81_21870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWV81_21875	COG0542	response to heat
AWV81_21890	COG0708	Exodeoxyribonuclease III
AWV81_21895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWV81_21900	COG0629	single-stranded DNA binding
AWV81_21905	COG0360	Binds together with S18 to 16S ribosomal RNA
AWV81_21910	COG0012	GTP binding
AWV81_21915	COG0243	molybdopterin cofactor binding
AWV81_21920	COG4481	Protein conserved in bacteria
AWV81_21925	COG3949	Membrane
AWV81_21935	COG1475	DNA binding
AWV81_21940	COG1192	Involved in chromosome partitioning
AWV81_21950	COG1475	DNA binding
AWV81_21955	COG0357	Ribosomal RNA small subunit methyltransferase G
AWV81_21960	COG0445	tRNA wobble uridine modification
AWV81_21965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWV81_21970	COG1847	R3H domain protein
AWV81_21975	COG0706	membrane insertase activity
AWV81_21980	COG0594	ribonuclease P activity
AWV81_21985	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AWV81_22020	COG0457	Tetratricopeptide repeat
AWV81_22155	COG3883	PFAM NLP P60 protein
AWV81_22155	COG0791	NLP P60 protein
AWV81_22210	COG0629	single-stranded DNA binding
AWV81_22225	COG0582	viral genome integration into host DNA
AWV81_22255	COG1793	dna ligase
AWV81_22270	COG1525	nuclease
AWV81_22390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII