locus-tag	class	description
EO946_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EO946_00010	COG0592	DNA-directed DNA polymerase activity
EO946_00015	COG2501	S4 domain
EO946_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EO946_00030	COG0187	DNA topoisomerase II activity
EO946_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EO946_00070	COG0517	IMP dehydrogenase activity
EO946_00070	COG0516	GMP reductase activity
EO946_00075	COG1686	Belongs to the peptidase S11 family
EO946_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EO946_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EO946_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EO946_00100	COG1428	Deoxynucleoside kinase
EO946_00105	COG1428	Deoxynucleoside kinase
EO946_00110	COG1388	LysM domain
EO946_00110	COG3858	chitin binding
EO946_00115	COG1335	isochorismatase
EO946_00120	COG0590	tRNA wobble adenosine to inosine editing
EO946_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EO946_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EO946_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EO946_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EO946_00190	COG3853	Toxic anion resistance protein (TelA)
EO946_00195	COG1982	Orn Lys Arg decarboxylase major
EO946_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EO946_00205	COG3870	Protein conserved in bacteria
EO946_00210	COG1728	Protein conserved in bacteria
EO946_00215	COG0470	DNA polymerase III
EO946_00220	COG1774	PSP1 C-terminal conserved region
EO946_00225	COG4467	Involved in initiation control of chromosome replication
EO946_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EO946_00235	COG2827	Endonuclease containing a URI domain
EO946_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EO946_00245	COG2002	toxin-antitoxin pair type II binding
EO946_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EO946_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EO946_00255	COG0084	hydrolase, TatD family'
EO946_00260	COG3583	domain protein
EO946_00260	COG3584	3D domain protein
EO946_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EO946_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EO946_00280	COG4466	Protein conserved in bacteria
EO946_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EO946_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EO946_00300	COG0251	oxidation-reduction process
EO946_00305	COG2088	sporulation resulting in formation of a cellular spore
EO946_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EO946_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EO946_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EO946_00325	COG0193	aminoacyl-tRNA hydrolase activity
EO946_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EO946_00340	COG2002	toxin-antitoxin pair type II binding
EO946_00345	COG2244	polysaccharide biosynthetic process
EO946_00350	COG3956	TIGRFAM MazG family protein
EO946_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EO946_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EO946_00375	COG1098	S1 RNA binding domain
EO946_00390	COG2208	phosphoserine phosphatase activity
EO946_00395	COG2304	oxidoreductase activity
EO946_00400	COG0515	serine threonine protein kinase
EO946_00405	COG0037	tRNA processing
EO946_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EO946_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EO946_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EO946_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EO946_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EO946_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EO946_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
EO946_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EO946_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EO946_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EO946_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EO946_00470	COG1396	sequence-specific DNA binding
EO946_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EO946_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EO946_00560	COG4463	regulation of RNA biosynthetic process
EO946_00565	COG3880	PFAM UvrB UvrC protein
EO946_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EO946_00575	COG0542	response to heat
EO946_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EO946_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EO946_00590	COG4956	integral membrane protein (PIN domain superfamily)
EO946_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EO946_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EO946_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EO946_00610	COG1045	serine acetyltransferase
EO946_00615	COG0215	cysteine-tRNA ligase activity
EO946_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EO946_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EO946_00630	COG3688	RNA-binding protein containing a PIN domain
EO946_00635	COG1595	DNA-templated transcription, initiation
EO946_00640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EO946_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EO946_00650	COG0250	Participates in transcription elongation, termination and antitermination
EO946_00655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EO946_00660	COG0081	regulation of translation
EO946_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EO946_00670	COG0222	ribosome binding
EO946_00675	COG2813	Specifically methylates the guanine in position
EO946_00680	COG0085	RNA polymerase activity
EO946_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EO946_00690	COG1358	cellular component organization or biogenesis
EO946_00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EO946_00700	COG0049	tRNA binding
EO946_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EO946_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EO946_00715	COG0596	Alpha beta hydrolase
EO946_00720	COG0051	transcription antitermination factor activity, RNA binding
EO946_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EO946_00730	COG0088	Forms part of the polypeptide exit tunnel
EO946_00735	COG0089	rRNA binding
EO946_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EO946_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EO946_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EO946_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EO946_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EO946_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
EO946_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EO946_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EO946_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EO946_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EO946_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EO946_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EO946_00815	COG1841	ribosomal large subunit assembly
EO946_00820	COG0200	Binds to the 23S rRNA
EO946_00825	COG0201	protein transport
EO946_00830	COG0563	adenylate kinase activity
EO946_00835	COG0024	Methionine aminopeptidase
EO946_00840	COG2163	COG2163 Ribosomal protein L14E L6E L27E
EO946_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EO946_00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EO946_00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EO946_00865	COG0202	RNA polymerase activity
EO946_00870	COG0203	ribosomal protein L17
EO946_00875	COG1122	ATPase activity
EO946_00880	COG1122	ATPase activity
EO946_00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EO946_00890	COG0101	tRNA pseudouridine synthase activity
EO946_00910	COG2226	methyltransferase
EO946_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
EO946_00925	COG0489	protein tyrosine kinase activity
EO946_00935	COG2194	sulfuric ester hydrolase activity
EO946_00940	COG0726	polysaccharide deacetylase
EO946_01025	COG0659	secondary active sulfate transmembrane transporter activity
EO946_01030	COG0385	Bile acid
EO946_01035	COG2819	hydrolase of the alpha beta superfamily
EO946_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EO946_01055	COG2207	Transcriptional regulator
EO946_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EO946_01060	COG3876	Protein conserved in bacteria
EO946_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
EO946_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EO946_01075	COG1263	PTS System
EO946_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_01080	COG1737	Transcriptional regulator
EO946_01085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EO946_01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EO946_01095	COG1683	Conserved Protein
EO946_01125	COG1595	DNA-templated transcription, initiation
EO946_01130	COG5662	AntiSigma factor
EO946_01135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EO946_01140	COG4856	YbbR-like protein
EO946_01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EO946_01160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EO946_01165	COG3002	Belongs to the UPF0753 family
EO946_01180	COG5609	conserved protein (DUF2294)
EO946_01190	COG0596	Alpha beta hydrolase
EO946_01195	COG0745	RESPONSE REGULATOR receiver
EO946_01200	COG0642	Histidine kinase
EO946_01210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EO946_01220	COG2211	Major facilitator Superfamily
EO946_01230	COG0028	Belongs to the TPP enzyme family
EO946_01230	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
EO946_01280	COG0515	serine threonine protein kinase
EO946_01295	COG1113	amino acid transport
EO946_01310	COG2602	Beta-lactamase
EO946_01315	COG2124	cytochrome p450
EO946_01325	COG1283	sodium-dependent phosphate transmembrane transporter activity
EO946_01330	COG0584	glycerophosphoryl diester phosphodiesterase
EO946_01335	COG2271	Major facilitator Superfamily
EO946_01350	COG0456	acetyltransferase
EO946_01350	COG1846	Transcriptional regulator
EO946_01355	COG2271	Major facilitator Superfamily
EO946_01370	COG0697	spore germination
EO946_01375	COG1917	Cupin 2, conserved barrel domain protein
EO946_01375	COG2207	Transcriptional regulator
EO946_01380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EO946_01385	COG3591	Belongs to the peptidase S1B family
EO946_01395	COG0596	Alpha beta hydrolase
EO946_01400	COG1183	phosphatidylcholine synthase activity
EO946_01405	COG0586	Pfam SNARE associated Golgi protein
EO946_01410	COG0688	phosphatidylethanolamine metabolic process
EO946_01420	COG2312	Erythromycin esterase
EO946_01430	COG1301	dicarboxylic acid transport
EO946_01440	COG0363	glucosamine-6-phosphate deaminase activity
EO946_01460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EO946_01465	COG0833	amino acid
EO946_01470	COG2040	homocysteine
EO946_01480	COG1115	amino acid carrier protein
EO946_01485	COG2066	Belongs to the glutaminase family
EO946_01490	COG4191	Histidine kinase
EO946_01495	COG0784	Response regulator, receiver
EO946_01500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EO946_01505	COG1012	belongs to the aldehyde dehydrogenase family
EO946_01510	COG2271	Major facilitator Superfamily
EO946_01515	COG4948	Mandelate Racemase Muconate Lactonizing
EO946_01520	COG2186	Transcriptional regulator
EO946_01525	COG2721	sulfolactate sulfo-lyase activity
EO946_01530	COG3173	Aminoglycoside phosphotransferase
EO946_01540	COG0745	RESPONSE REGULATOR receiver
EO946_01545	COG2205	protein histidine kinase activity
EO946_01550	COG1131	(ABC) transporter
EO946_01570	COG3773	Cell wall hydrolase
EO946_01575	COG2304	oxidoreductase activity
EO946_01585	COG3540	Alkaline phosphatase
EO946_01590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EO946_01595	COG0805	protein transport
EO946_01600	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EO946_01605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EO946_01610	COG0477	Major facilitator Superfamily
EO946_01615	COG1309	transcriptional regulator
EO946_01620	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EO946_01625	COG1714	RDD family
EO946_01630	COG3012	SEC-C Motif Domain Protein
EO946_01630	COG1405	negative regulation of cell septum assembly
EO946_01645	COG0667	Aldo Keto reductase
EO946_01660	COG1595	DNA-templated transcription, initiation
EO946_01685	COG1876	peptidase activity
EO946_01690	COG0457	Tetratricopeptide repeat
EO946_01695	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_01700	COG0366	Alpha amylase catalytic
EO946_01705	COG0803	Belongs to the bacterial solute-binding protein 9 family
EO946_01710	COG1121	(ABC) transporter
EO946_01715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EO946_01720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EO946_01725	COG2310	stress, protein
EO946_01730	COG2310	stress, protein
EO946_01735	COG2310	stress, protein
EO946_01740	COG0861	Integral membrane protein TerC family
EO946_01750	COG3853	Toxic anion resistance protein (TelA)
EO946_01755	COG0477	Major facilitator Superfamily
EO946_01760	COG2814	Major facilitator Superfamily
EO946_01765	COG0640	Transcriptional regulator
EO946_01770	COG0517	IMP dehydrogenase activity
EO946_01770	COG4175	Glycine betaine
EO946_01775	COG4176	ABC-type proline glycine betaine transport system permease component
EO946_01780	COG2113	Glycine betaine
EO946_01785	COG1473	amidohydrolase
EO946_01790	COG1288	antiporter activity
EO946_01800	COG0366	Alpha amylase catalytic
EO946_01805	COG0039	L-malate dehydrogenase activity
EO946_01810	COG1620	l-lactate permease
EO946_01815	COG2814	Major facilitator Superfamily
EO946_01820	COG1846	Transcriptional regulator
EO946_01825	COG1280	lysine exporter protein (LysE YggA)
EO946_01830	COG3403	YqcI/YcgG family
EO946_01835	COG1113	amino acid transport
EO946_01840	COG3665	Urea carboxylase-associated protein
EO946_01845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EO946_01850	COG1660	Displays ATPase and GTPase activities
EO946_01855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EO946_01860	COG2226	methyltransferase
EO946_01865	COG0583	DNA-binding transcription factor activity
EO946_01870	COG3458	cephalosporin-C deacetylase activity
EO946_01875	COG3541	Predicted nucleotidyltransferase
EO946_01880	COG0506	proline dehydrogenase activity
EO946_01885	COG1012	belongs to the aldehyde dehydrogenase family
EO946_01890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EO946_01895	COG2508	Transcriptional regulator
EO946_01900	COG3689	TIGRFAM TIGR03943 family protein
EO946_01905	COG0701	Predicted permease
EO946_01910	COG2267	carboxylic ester hydrolase activity
EO946_01915	COG0492	ferredoxin-NADP+ reductase activity
EO946_01920	COG1587	Uroporphyrinogen-III synthase
EO946_01920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EO946_01925	COG2146	nitrite reductase [NAD(P)H] activity
EO946_01930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EO946_01935	COG0243	molybdopterin cofactor binding
EO946_01940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EO946_01945	COG2223	nitrite transmembrane transporter activity
EO946_01950	COG1469	GTP cyclohydrolase I activity
EO946_01955	COG1376	ErfK ybiS ycfS ynhG family protein
EO946_01955	COG1376	ErfK ybiS ycfS ynhG family protein
EO946_01965	COG0523	cobalamin synthesis protein
EO946_01970	COG0765	amino acid transport
EO946_01975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EO946_01980	COG1714	RDD family
EO946_01990	COG1846	Transcriptional regulator
EO946_02000	COG3842	ATPase activity
EO946_02005	COG2723	6-phospho-beta-galactosidase activity
EO946_02015	COG3209	COG3209 Rhs family protein
EO946_02020	COG3290	protein histidine kinase activity
EO946_02020	COG0840	transmembrane signaling receptor activity
EO946_02025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EO946_02030	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EO946_02035	COG1733	regulation of RNA biosynthetic process
EO946_02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_02055	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EO946_02060	COG2814	Major facilitator Superfamily
EO946_02070	COG0697	spore germination
EO946_02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EO946_02085	COG2364	Membrane
EO946_02090	COG1126	abc transporter atp-binding protein
EO946_02095	COG0765	amino acid transport
EO946_02100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EO946_02105	COG0583	DNA-binding transcription factor activity
EO946_02110	COG0163	prenyltransferase activity
EO946_02115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EO946_02130	COG0596	Alpha beta hydrolase
EO946_02135	COG3104	oligopeptide transport
EO946_02140	COG5434	Belongs to the glycosyl hydrolase 28 family
EO946_02150	COG0697	spore germination
EO946_02160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EO946_02165	COG1136	(ABC) transporter
EO946_02170	COG0577	efflux transmembrane transporter activity
EO946_02175	COG0745	RESPONSE REGULATOR receiver
EO946_02180	COG5002	protein histidine kinase activity
EO946_02180	COG3850	Histidine kinase
EO946_02185	COG0457	Tetratricopeptide repeat
EO946_02200	COG0527	aspartate kinase activity
EO946_02205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_02210	COG4605	iron ion homeostasis
EO946_02215	COG4604	ABC transporter, ATP-binding protein
EO946_02220	COG4607	ABC-type enterochelin transport system periplasmic component
EO946_02225	COG2814	Major facilitator Superfamily
EO946_02230	COG1309	transcriptional regulator
EO946_02235	COG0778	Nitroreductase
EO946_02240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EO946_02245	COG0640	Transcriptional regulator
EO946_02250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EO946_02255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EO946_02260	COG1012	belongs to the aldehyde dehydrogenase family
EO946_02265	COG4975	Glucose uptake
EO946_02270	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_02275	COG4549	nuclear export factor GLE1
EO946_02280	COG2372	response to copper ion
EO946_02280	COG1276	copper resistance
EO946_02285	COG1349	DNA-binding transcription factor activity
EO946_02295	COG2213	PTS system mannitol-specific
EO946_02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EO946_02305	COG0246	Mannitol dehydrogenase
EO946_02310	COG0473	3-isopropylmalate dehydrogenase activity
EO946_02315	COG0681	Belongs to the peptidase S26 family
EO946_02320	COG0412	Dienelactone hydrolase
EO946_02325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EO946_02335	COG0561	phosphatase activity
EO946_02340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EO946_02345	COG1914	H( )-stimulated, divalent metal cation uptake system
EO946_02350	COG4336	lyase activity
EO946_02355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EO946_02360	COG1984	allophanate hydrolase subunit 2
EO946_02365	COG1414	Transcriptional regulator
EO946_02370	COG2755	lipolytic protein G-D-S-L family
EO946_02380	COG2329	Antibiotic biosynthesis monooxygenase
EO946_02385	COG0768	penicillin binding
EO946_02390	COG4989	oxidoreductase activity
EO946_02395	COG3711	transcriptional antiterminator
EO946_02400	COG0318	PFAM AMP-dependent synthetase and ligase
EO946_02405	COG2226	methyltransferase
EO946_02410	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_02415	COG1917	Cupin 2, conserved barrel domain protein
EO946_02420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EO946_02425	COG3871	stress protein (general stress protein 26)
EO946_02435	COG2814	Major facilitator Superfamily
EO946_02440	COG1522	sequence-specific DNA binding
EO946_02445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EO946_02445	COG0551	DNA topoisomerase type I activity
EO946_02450	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EO946_02455	COG3706	GGDEF domain
EO946_02460	COG5298	Protein conserved in bacteria
EO946_02465	COG1215	transferase activity, transferring glycosyl groups
EO946_02475	COG0531	amino acid
EO946_02480	COG0494	nUDIX hydrolase
EO946_02485	COG0028	Belongs to the TPP enzyme family
EO946_02495	COG1914	H( )-stimulated, divalent metal cation uptake system
EO946_02500	COG2261	transglycosylase associated protein
EO946_02505	COG4876	unkown
EO946_02510	COG2217	Heavy metal translocating P-type atpase
EO946_02515	COG3729	General stress protein
EO946_02525	COG2329	Antibiotic biosynthesis monooxygenase
EO946_02530	COG3546	catalase activity
EO946_02535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EO946_02540	COG3290	protein histidine kinase activity
EO946_02545	COG4565	transcriptional regulatory protein
EO946_02550	COG1301	dicarboxylic acid transport
EO946_02555	COG0628	permease
EO946_02560	COG1301	dicarboxylic acid transport
EO946_02565	COG1131	(ABC) transporter
EO946_02570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EO946_02580	COG1960	acyl-CoA dehydrogenase activity
EO946_02595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EO946_02600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_02605	COG1181	Belongs to the D-alanine--D-alanine ligase family
EO946_02610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EO946_02620	COG0513	Belongs to the DEAD box helicase family
EO946_02625	COG3402	PFAM membrane-flanked domain
EO946_02630	COG3428	Bacterial PH domain
EO946_02635	COG0705	Rhomboid family
EO946_02640	COG0736	holo-[acyl-carrier-protein] synthase activity
EO946_02645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EO946_02650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EO946_02655	COG0864	Transcriptional regulator
EO946_02660	COG2337	Toxic component of a toxin-antitoxin (TA) module
EO946_02665	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_02670	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_02675	COG2172	sigma factor antagonist activity
EO946_02680	COG2208	phosphoserine phosphatase activity
EO946_02685	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_02690	COG2172	sigma factor antagonist activity
EO946_02695	COG1191	sigma factor activity
EO946_02700	COG2208	phosphoserine phosphatase activity
EO946_02705	COG2183	response to ionizing radiation
EO946_02715	COG3091	SprT-like family
EO946_02760	COG0789	Transcriptional regulator
EO946_02765	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_02770	COG0667	Aldo Keto reductase
EO946_02775	COG4221	oxidoreductase activity
EO946_02780	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_02790	COG4221	oxidoreductase activity
EO946_02795	COG3239	Fatty acid desaturase
EO946_02805	COG1278	Cold shock
EO946_02810	COG1329	Transcriptional regulator
EO946_02820	COG1396	sequence-specific DNA binding
EO946_02825	COG2207	Transcriptional regulator
EO946_02825	COG3708	Transcriptional regulator
EO946_02835	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EO946_02850	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EO946_02855	COG1522	sequence-specific DNA binding
EO946_02860	COG0697	spore germination
EO946_02865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EO946_02870	COG2030	dehydratase
EO946_02875	COG3545	Serine hydrolase
EO946_02880	COG1733	regulation of RNA biosynthetic process
EO946_02885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EO946_02895	COG0640	Transcriptional regulator
EO946_02900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EO946_02905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EO946_02910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EO946_02915	COG0697	spore germination
EO946_02920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EO946_02925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EO946_02930	COG0640	Transcriptional regulator
EO946_02935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EO946_02950	COG4585	Histidine kinase
EO946_02955	COG2197	response regulator
EO946_02960	COG2409	Drug exporters of the RND superfamily
EO946_02975	COG1114	Component of the transport system for branched-chain amino acids
EO946_02985	COG1811	Na channel or pump
EO946_02990	COG0789	Transcriptional regulator
EO946_02990	COG4978	Transcriptional regulator
EO946_02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EO946_03000	COG0778	Nitroreductase
EO946_03005	COG0346	lactoylglutathione lyase activity
EO946_03010	COG2259	Doxx family
EO946_03015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_03020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EO946_03040	COG2323	membrane
EO946_03045	COG0071	Belongs to the small heat shock protein (HSP20) family
EO946_03060	COG1309	transcriptional regulator
EO946_03070	COG0456	acetyltransferase
EO946_03080	COG0673	inositol 2-dehydrogenase activity
EO946_03085	COG1609	Transcriptional regulator
EO946_03100	COG2814	Major facilitator Superfamily
EO946_03115	COG1113	amino acid transport
EO946_03120	COG2318	DinB family
EO946_03125	COG1846	Transcriptional regulator
EO946_03130	COG2409	Drug exporters of the RND superfamily
EO946_03130	COG1033	growth of symbiont in host cell
EO946_03135	COG0778	Nitroreductase
EO946_03140	COG1846	Transcriptional regulator
EO946_03145	COG1396	sequence-specific DNA binding
EO946_03160	COG2814	Major facilitator Superfamily
EO946_03165	COG0730	response to heat
EO946_03170	COG1802	Transcriptional regulator
EO946_03175	COG3858	chitin binding
EO946_03175	COG1388	LysM domain
EO946_03180	COG1819	glycosyl
EO946_03195	COG1785	Belongs to the alkaline phosphatase family
EO946_03210	COG1078	dGTPase activity
EO946_03215	COG1388	LysM domain
EO946_03220	COG2814	Major facilitator Superfamily
EO946_03225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EO946_03230	COG1447	Phosphotransferase system cellobiose-specific component IIA
EO946_03235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EO946_03240	COG2723	6-phospho-beta-galactosidase activity
EO946_03245	COG2188	Transcriptional regulator
EO946_03250	COG1940	carbohydrate kinase activity
EO946_03255	COG1482	cell wall glycoprotein biosynthetic process
EO946_03260	COG4124	Belongs to the glycosyl hydrolase 26 family
EO946_03305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EO946_03310	COG0802	atpase or kinase
EO946_03315	COG1214	PFAM Peptidase M22, glycoprotease
EO946_03320	COG0456	acetyltransferase
EO946_03325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EO946_03330	COG0488	(ABC) transporter
EO946_03335	COG0315	cyclic pyranopterin monophosphate synthase activity
EO946_03340	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EO946_03345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EO946_03350	COG0805	protein transport
EO946_03360	COG1266	CAAX protease self-immunity
EO946_03365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EO946_03370	COG0459	protein refolding
EO946_03380	COG1073	alpha beta
EO946_03385	COG0457	Tetratricopeptide repeat
EO946_03390	COG1063	alcohol dehydrogenase
EO946_03395	COG2211	Major facilitator Superfamily
EO946_03400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EO946_03405	COG1842	Phage shock protein A
EO946_03410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EO946_03415	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EO946_03420	COG4260	virion core protein, lumpy skin disease virus
EO946_03430	COG2814	Major facilitator Superfamily
EO946_03435	COG1063	alcohol dehydrogenase
EO946_03440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EO946_03445	COG0823	Involved in the tonB-independent uptake of proteins
EO946_03465	COG2267	carboxylic ester hydrolase activity
EO946_03475	COG2132	Multicopper oxidase
EO946_03480	COG1113	amino acid transport
EO946_03490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EO946_03495	COG0714	Associated with various cellular activities
EO946_03500	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EO946_03505	COG1305	Transglutaminase-like
EO946_03510	COG0519	Catalyzes the synthesis of GMP from XMP
EO946_03510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EO946_03515	COG2252	PERMEase
EO946_03520	COG3064	Membrane
EO946_03530	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EO946_03540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EO946_03545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EO946_03550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EO946_03555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EO946_03560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EO946_03565	COG0047	phosphoribosylformylglycinamidine synthase activity
EO946_03570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EO946_03575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EO946_03580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EO946_03585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EO946_03590	COG0138	bifunctional purine biosynthesis protein purh
EO946_03595	COG0151	Belongs to the GarS family
EO946_03600	COG1522	sequence-specific DNA binding
EO946_03605	COG0531	amino acid
EO946_03615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EO946_03620	COG1470	cell adhesion involved in biofilm formation
EO946_03625	COG4496	protein, YerC YecD
EO946_03630	COG0069	glutamate synthase activity
EO946_03635	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EO946_03640	COG0210	DNA helicase
EO946_03645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EO946_03650	COG4851	CamS sex pheromone cAM373 precursor
EO946_03655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EO946_03660	COG1285	pathogenesis
EO946_03665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EO946_03670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EO946_03675	COG0154	amidase activity
EO946_03680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EO946_03685	COG1309	transcriptional regulator
EO946_03690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EO946_03695	COG1597	lipid kinase activity
EO946_03700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EO946_03705	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EO946_03710	COG0732	type I restriction modification DNA specificity domain
EO946_03715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EO946_03735	COG5444	nuclease activity
EO946_03740	COG3391	amine dehydrogenase activity
EO946_03745	COG0457	Tetratricopeptide repeat
EO946_03755	COG0217	transcriptional regulatory protein
EO946_03765	COG1309	transcriptional regulator
EO946_03770	COG3631	Ketosteroid isomerase-related protein
EO946_03775	COG0702	epimerase
EO946_03780	COG2159	amidohydrolase
EO946_03785	COG1309	transcriptional regulator
EO946_03800	COG3546	catalase activity
EO946_03805	COG0454	-acetyltransferase
EO946_03815	COG5578	integral membrane protein
EO946_03820	COG2972	Histidine kinase
EO946_03825	COG4753	response regulator
EO946_03825	COG2207	Transcriptional regulator
EO946_03830	COG1653	transport
EO946_03835	COG1175	transmembrane transport
EO946_03840	COG0395	ABC-type sugar transport system, permease component
EO946_03845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EO946_03850	COG2207	Transcriptional regulator
EO946_03855	COG2755	lipolytic protein G-D-S-L family
EO946_03865	COG5578	integral membrane protein
EO946_03870	COG3401	FG-GAP repeat protein
EO946_03875	COG3401	FG-GAP repeat protein
EO946_03880	COG2755	lipolytic protein G-D-S-L family
EO946_03885	COG1874	Beta-galactosidase
EO946_03895	COG1653	transport
EO946_03900	COG4209	transmembrane transport
EO946_03905	COG0395	ABC-type sugar transport system, permease component
EO946_03910	COG1486	melibiose metabolic process
EO946_03915	COG2323	membrane
EO946_03920	COG2329	Antibiotic biosynthesis monooxygenase
EO946_03925	COG0346	lactoylglutathione lyase activity
EO946_03935	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_03940	COG5583	Uncharacterized small protein (DUF2292)
EO946_03945	COG0670	Belongs to the BI1 family
EO946_03950	COG1846	Transcriptional regulator
EO946_03955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EO946_03965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EO946_03965	COG2124	cytochrome p450
EO946_03970	COG1368	sulfuric ester hydrolase activity
EO946_03975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EO946_03980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EO946_03985	COG1442	glycosyl transferase family 8
EO946_03990	COG1216	Glycosyl transferase, family 2
EO946_03995	COG1442	glycosyl transferase family 8
EO946_04000	COG2223	nitrite transmembrane transporter activity
EO946_04005	COG1011	Hydrolase
EO946_04010	COG0531	amino acid
EO946_04015	COG1012	belongs to the aldehyde dehydrogenase family
EO946_04020	COG0840	transmembrane signaling receptor activity
EO946_04025	COG0488	(ABC) transporter
EO946_04035	COG0789	Transcriptional regulator
EO946_04040	COG2814	Major facilitator Superfamily
EO946_04050	COG0488	(ABC) transporter
EO946_04055	COG0513	Belongs to the DEAD box helicase family
EO946_04060	COG0456	acetyltransferase
EO946_04065	COG2130	NADP-dependent
EO946_04070	COG1120	ATPase activity
EO946_04075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_04080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_04085	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EO946_04100	COG3866	Pectate lyase
EO946_04105	COG0471	metal ion transport
EO946_04110	COG3290	protein histidine kinase activity
EO946_04115	COG4565	transcriptional regulatory protein
EO946_04120	COG3181	Tripartite tricarboxylate transporter family receptor
EO946_04125	COG2851	Citrate transporter
EO946_04130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EO946_04135	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EO946_04140	COG1254	Belongs to the acylphosphatase family
EO946_04145	COG2258	MOSC domain
EO946_04165	COG0024	Methionine aminopeptidase
EO946_04170	COG1263	PTS System
EO946_04170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_04175	COG1368	sulfuric ester hydrolase activity
EO946_04190	COG1115	amino acid carrier protein
EO946_04195	COG0531	amino acid
EO946_04210	COG0697	spore germination
EO946_04215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_04215	COG1263	PTS System
EO946_04220	COG0366	Alpha amylase catalytic
EO946_04225	COG2188	Transcriptional regulator
EO946_04230	COG0778	Nitroreductase
EO946_04235	COG0737	Belongs to the 5'-nucleotidase family
EO946_04240	COG0693	protein deglycase activity
EO946_04245	COG2814	Major facilitator Superfamily
EO946_04250	COG4840	Belongs to the UPF0435 family
EO946_04255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EO946_04260	COG4980	gas vesicle protein
EO946_04265	COG1295	ribonuclease BN
EO946_04270	COG0477	Major facilitator Superfamily
EO946_04275	COG0387	Pfam Sodium calcium exchanger
EO946_04285	COG0668	transmembrane transport
EO946_04290	COG0535	radical SAM domain protein
EO946_04300	COG0726	polysaccharide deacetylase
EO946_04305	COG2084	Dehydrogenase
EO946_04310	COG0598	Magnesium transport protein CorA
EO946_04315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EO946_04325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EO946_04330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EO946_04340	COG4637	Psort location Cytoplasmic, score
EO946_04350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EO946_04355	COG0022	dehydrogenase e1 component
EO946_04360	COG0508	dehydrogenase complex catalyzes the overall conversion of
EO946_04365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EO946_04370	COG3284	Transcriptional regulator
EO946_04380	COG1742	UPF0060 membrane protein
EO946_04400	COG4842	Belongs to the WXG100 family
EO946_04405	COG1486	melibiose metabolic process
EO946_04410	COG1737	Transcriptional regulator
EO946_04415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_04415	COG1263	PTS System
EO946_04420	COG1132	(ABC) transporter
EO946_04425	COG1132	(ABC) transporter
EO946_04430	COG2259	Doxx family
EO946_04435	COG2514	catechol 2,3-dioxygenase activity
EO946_04440	COG4585	Histidine kinase
EO946_04445	COG2197	response regulator
EO946_04450	COG1131	(ABC) transporter
EO946_04455	COG1511	domain protein
EO946_04455	COG0842	Transport permease protein
EO946_04460	COG0842	Transport permease protein
EO946_04470	COG1695	Transcriptional regulator
EO946_04475	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EO946_04480	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EO946_04485	COG2318	DinB family
EO946_04490	COG2814	Major facilitator Superfamily
EO946_04495	COG1846	Transcriptional regulator
EO946_04500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EO946_04500	COG0392	lysyltransferase activity
EO946_04505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EO946_04510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_04515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_04525	COG0778	Nitroreductase
EO946_04540	COG1090	epimerase
EO946_04545	COG2137	regulation of response to DNA damage stimulus
EO946_04560	COG2814	Major facilitator Superfamily
EO946_04575	COG3103	Sh3 type 3 domain protein
EO946_04580	COG5658	integral membrane protein
EO946_04585	COG0596	Alpha beta hydrolase
EO946_04590	COG0463	Glycosyl transferase, family 2
EO946_04595	COG4485	Bacterial membrane protein, YfhO
EO946_04600	COG1988	membrane-bound metal-dependent
EO946_04605	COG1194	a g-specific adenine glycosylase
EO946_04615	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_04630	COG3557	Belongs to the UPF0374 family
EO946_04635	COG1132	(ABC) transporter
EO946_04640	COG4129	membrane
EO946_04645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EO946_04650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EO946_04655	COG0735	belongs to the Fur family
EO946_04765	COG4326	sporulation control protein
EO946_04775	COG5577	PFAM Coat F domain
EO946_04780	COG3340	Belongs to the peptidase S51 family
EO946_04785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EO946_04795	COG0753	catalase activity
EO946_04800	COG1116	anion transmembrane transporter activity
EO946_04805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EO946_04810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EO946_04815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EO946_04825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EO946_04835	COG1476	TRANSCRIPTIONal
EO946_04845	COG3382	B3 4 domain protein
EO946_04850	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EO946_04860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EO946_04865	COG0789	Transcriptional regulator
EO946_04870	COG1664	Polymer-forming cytoskeletal
EO946_04875	COG1664	Polymer-forming cytoskeletal
EO946_04880	COG2766	serine protein kinase
EO946_04885	COG2718	Belongs to the UPF0229 family
EO946_04890	COG1846	Transcriptional regulator
EO946_04895	COG1566	PFAM secretion protein HlyD family protein
EO946_04900	COG2814	Major facilitator Superfamily
EO946_04905	COG0655	NAD(P)H dehydrogenase (quinone) activity
EO946_04920	COG1725	Transcriptional regulator
EO946_04925	COG1131	(ABC) transporter
EO946_04930	COG1131	(ABC) transporter
EO946_04940	COG1278	Cold shock
EO946_04950	COG1464	Belongs to the NlpA lipoprotein family
EO946_04955	COG3706	GGDEF domain
EO946_04960	COG1823	symporter activity
EO946_04980	COG5577	PFAM Coat F domain
EO946_04985	COG0737	Belongs to the 5'-nucleotidase family
EO946_04985	COG4085	toxin activity
EO946_04985	COG1525	nuclease
EO946_04990	COG3764	Sortase (surface protein transpeptidase)
EO946_04995	COG0564	pseudouridine synthase activity
EO946_05005	COG0517	IMP dehydrogenase activity
EO946_05010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EO946_05015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EO946_05015	COG3153	acetyltransferase
EO946_05025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EO946_05030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EO946_05035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EO946_05040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EO946_05045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EO946_05050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EO946_05055	COG4585	Histidine kinase
EO946_05055	COG2203	Gaf domain
EO946_05060	COG2197	response regulator
EO946_05065	COG0431	NADPH-dependent FMN reductase
EO946_05080	COG0791	NLP P60 protein
EO946_05080	COG1388	LysM domain
EO946_05085	COG1959	2 iron, 2 sulfur cluster binding
EO946_05090	COG0668	transmembrane transport
EO946_05095	COG2719	SpoVR family
EO946_05100	COG1785	Belongs to the alkaline phosphatase family
EO946_05105	COG0791	NLP P60 protein
EO946_05105	COG1388	LysM domain
EO946_05110	COG0583	DNA-binding transcription factor activity
EO946_05115	COG0372	Belongs to the citrate synthase family
EO946_05120	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_05125	COG0531	amino acid
EO946_05130	COG0733	neurotransmitter:sodium symporter activity
EO946_05135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EO946_05140	COG0456	acetyltransferase
EO946_05155	COG1595	DNA-templated transcription, initiation
EO946_05160	COG0667	Aldo Keto reductase
EO946_05165	COG0204	Acyl-transferase
EO946_05170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EO946_05180	COG1253	flavin adenine dinucleotide binding
EO946_05185	COG0789	Transcriptional regulator
EO946_05190	COG0436	Aminotransferase
EO946_05195	COG1253	flavin adenine dinucleotide binding
EO946_05200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EO946_05205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EO946_05210	COG0584	glycerophosphoryl diester phosphodiesterase
EO946_05220	COG0668	transmembrane transport
EO946_05225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EO946_05230	COG0726	polysaccharide deacetylase
EO946_05235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EO946_05240	COG1757	Na H antiporter
EO946_05245	COG0589	response to stress
EO946_05255	COG1132	(ABC) transporter
EO946_05260	COG1132	(ABC) transporter
EO946_05265	COG0702	epimerase
EO946_05290	COG0189	ligase activity
EO946_05295	COG0189	ligase activity
EO946_05300	COG4399	Belongs to the UPF0754 family
EO946_05305	COG3679	Belongs to the UPF0342 family
EO946_05310	COG4335	DNA alkylation repair
EO946_05315	COG0561	phosphatase activity
EO946_05320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EO946_05325	COG0475	glutathione-regulated potassium exporter activity
EO946_05330	COG0490	domain, Protein
EO946_05340	COG1024	Enoyl-CoA hydratase
EO946_05350	COG4152	abc transporter atp-binding protein
EO946_05355	COG1668	transmembrane transport
EO946_05360	COG0420	3'-5' exonuclease activity
EO946_05365	COG4717	serine-type aminopeptidase activity
EO946_05370	COG3481	metal-dependent phosphohydrolase, HD sub domain
EO946_05380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EO946_05410	COG1846	Transcriptional regulator
EO946_05415	COG4980	gas vesicle protein
EO946_05430	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EO946_05435	COG0537	adenosine 5'-monophosphoramidase activity
EO946_05440	COG1131	(ABC) transporter
EO946_05445	COG4473	ABC transporter
EO946_05455	COG1473	amidohydrolase
EO946_05460	COG3069	C4-dicarboxylate transmembrane transporter activity
EO946_05470	COG2329	Antibiotic biosynthesis monooxygenase
EO946_05475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EO946_05480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EO946_05495	COG1309	transcriptional regulator
EO946_05500	COG1511	domain protein
EO946_05505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EO946_05510	COG4377	Putative membrane peptidase family (DUF2324)
EO946_05520	COG1363	Peptidase, m42
EO946_05525	COG4405	Protein conserved in bacteria
EO946_05530	COG1301	dicarboxylic acid transport
EO946_05540	COG1234	tRNA 3'-trailer cleavage
EO946_05545	COG0095	Lipoate-protein ligase
EO946_05550	COG0702	epimerase
EO946_05555	COG0318	PFAM AMP-dependent synthetase and ligase
EO946_05565	COG0501	Belongs to the peptidase M48B family
EO946_05575	COG0456	acetyltransferase
EO946_05580	COG0604	alcohol dehydrogenase
EO946_05585	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EO946_05590	COG0406	alpha-ribazole phosphatase activity
EO946_05595	COG0183	Belongs to the thiolase family
EO946_05600	COG0318	PFAM AMP-dependent synthetase and ligase
EO946_05605	COG1268	BioY protein
EO946_05610	COG0840	transmembrane signaling receptor activity
EO946_05615	COG0723	plastoquinol--plastocyanin reductase activity
EO946_05615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EO946_05620	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_05630	COG4903	ComK protein
EO946_05635	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_05645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EO946_05660	COG0398	Pfam SNARE associated Golgi protein
EO946_05665	COG0681	Belongs to the peptidase S26 family
EO946_05670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EO946_05675	COG1846	Transcriptional regulator
EO946_05685	COG0738	Major facilitator superfamily
EO946_05690	COG0673	inositol 2-dehydrogenase activity
EO946_05695	COG0561	phosphatase activity
EO946_05700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EO946_05705	COG1609	Transcriptional regulator
EO946_05710	COG3180	Ammonia monooxygenase
EO946_05715	COG0477	Major facilitator Superfamily
EO946_05715	COG2814	Major facilitator Superfamily
EO946_05720	COG4533	DNA binding
EO946_05730	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EO946_05735	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EO946_05740	COG1074	ATP-dependent DNA helicase activity
EO946_05745	COG0420	3'-5' exonuclease activity
EO946_05750	COG0419	ATPase involved in DNA repair
EO946_05755	COG1403	HNH endonuclease
EO946_05795	COG5337	Spore coat protein CotH
EO946_05800	COG0179	Fumarylacetoacetate (FAA) hydrolase
EO946_05810	COG1404	Belongs to the peptidase S8 family
EO946_05820	COG0367	asparagine synthase
EO946_05825	COG2318	DinB family
EO946_05830	COG1562	ergosterol biosynthetic process
EO946_05835	COG0534	Mate efflux family protein
EO946_05840	COG1917	Cupin 2, conserved barrel domain protein
EO946_05840	COG2207	Transcriptional regulator
EO946_05845	COG1609	Transcriptional regulator
EO946_05850	COG0673	inositol 2-dehydrogenase activity
EO946_05855	COG2318	DinB family
EO946_05860	COG1279	arginine transmembrane transporter activity
EO946_05865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EO946_05870	COG1357	PFAM Pentapeptide repeats (8 copies)
EO946_05875	COG2267	carboxylic ester hydrolase activity
EO946_05880	COG0529	Catalyzes the synthesis of activated sulfate
EO946_05885	COG2046	Belongs to the sulfate adenylyltransferase family
EO946_05890	COG0175	sulfate reduction
EO946_05895	COG2045	Belongs to the ComB family
EO946_05900	COG1809	phosphosulfolactate synthase activity
EO946_05905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EO946_05910	COG4948	Mandelate Racemase Muconate Lactonizing
EO946_05915	COG2814	Major facilitator Superfamily
EO946_05920	COG0454	-acetyltransferase
EO946_05925	COG2153	protein acetylation
EO946_05930	COG0646	methionine synthase
EO946_05930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EO946_05935	COG1666	GTP binding
EO946_05940	COG2996	Protein conserved in bacteria
EO946_05950	COG1307	EDD domain protein, DegV family
EO946_05955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EO946_05970	COG0561	phosphatase activity
EO946_05975	COG1073	alpha beta
EO946_05980	COG2151	metal-sulfur cluster biosynthetic enzyme
EO946_05990	COG0277	FAD linked oxidase domain protein
EO946_05995	COG2271	Major facilitator Superfamily
EO946_06000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EO946_06015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EO946_06020	COG0505	Belongs to the CarA family
EO946_06025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EO946_06030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EO946_06045	COG2267	carboxylic ester hydrolase activity
EO946_06055	COG1744	ABC transporter substrate-binding protein PnrA-like
EO946_06070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EO946_06075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EO946_06080	COG5504	Zn-dependent protease
EO946_06085	COG0444	Belongs to the ABC transporter superfamily
EO946_06090	COG4608	Belongs to the ABC transporter superfamily
EO946_06100	COG0601	transmembrane transport
EO946_06105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EO946_06115	COG0180	Tryptophanyl-tRNA synthetase
EO946_06125	COG4166	transmembrane transport
EO946_06130	COG0601	transmembrane transport
EO946_06135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EO946_06140	COG0444	Belongs to the ABC transporter superfamily
EO946_06145	COG4608	Belongs to the ABC transporter superfamily
EO946_06150	COG2814	Major facilitator Superfamily
EO946_06155	COG0456	acetyltransferase
EO946_06160	COG1393	Belongs to the ArsC family
EO946_06165	COG0861	Integral membrane protein TerC family
EO946_06175	COG4862	establishment of competence for transformation
EO946_06185	COG4469	Competence protein
EO946_06190	COG1164	Oligoendopeptidase f
EO946_06210	COG2346	COG2346, Truncated hemoglobins
EO946_06215	COG0741	lytic transglycosylase activity
EO946_06220	COG4116	CYTH
EO946_06230	COG2357	RelA SpoT domain protein
EO946_06235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EO946_06240	COG0564	pseudouridine synthase activity
EO946_06245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EO946_06250	COG0475	glutathione-regulated potassium exporter activity
EO946_06250	COG0569	domain protein
EO946_06255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EO946_06260	COG0352	thiamine-phosphate diphosphorylase activity
EO946_06265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EO946_06270	COG2104	thiamine diphosphate biosynthetic process
EO946_06275	COG2022	thiamine diphosphate biosynthetic process
EO946_06280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EO946_06285	COG0351	phosphomethylpyrimidine kinase
EO946_06290	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EO946_06345	COG0210	DNA helicase
EO946_06355	COG2153	protein acetylation
EO946_06360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EO946_06365	COG2382	esterase
EO946_06370	COG0626	cystathionine gamma-synthase activity
EO946_06375	COG0626	cystathionine gamma-synthase activity
EO946_06385	COG5505	Protein of unknown function (DUF819)
EO946_06410	COG0457	Tetratricopeptide repeat
EO946_06445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EO946_06445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EO946_06445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EO946_06450	COG1482	cell wall glycoprotein biosynthetic process
EO946_06470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EO946_06485	COG0109	protoheme IX farnesyltransferase activity
EO946_06495	COG0726	polysaccharide deacetylase
EO946_06510	COG5504	Zn-dependent protease
EO946_06515	COG2205	protein histidine kinase activity
EO946_06525	COG3383	formate dehydrogenase (NAD+) activity
EO946_06530	COG2427	Protein of unknown function (DUF1641)
EO946_06540	COG1051	belongs to the nudix hydrolase family
EO946_06550	COG2124	cytochrome p450
EO946_06555	COG1819	glycosyl
EO946_06565	COG1587	Uroporphyrinogen-III synthase
EO946_06570	COG0390	transport system, permease component
EO946_06575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EO946_06580	COG0697	spore germination
EO946_06585	COG4297	protein containing double-stranded beta helix domain
EO946_06595	COG1252	NADH dehydrogenase
EO946_06600	COG1904	glucuronate isomerase
EO946_06605	COG2211	Major facilitator Superfamily
EO946_06610	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EO946_06615	COG1063	alcohol dehydrogenase
EO946_06620	COG1312	Catalyzes the dehydration of D-mannonate
EO946_06625	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_06630	COG2271	Major facilitator Superfamily
EO946_06635	COG1609	Transcriptional regulator
EO946_06640	COG0246	Mannitol dehydrogenase
EO946_06645	COG2721	sulfolactate sulfo-lyase activity
EO946_06650	COG0730	response to heat
EO946_06655	COG2318	DinB family
EO946_06660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EO946_06665	COG0457	Tetratricopeptide repeat
EO946_06675	COG2350	Protein conserved in bacteria
EO946_06680	COG5632	N-Acetylmuramoyl-L-alanine amidase
EO946_06680	COG3409	Peptidoglycan-binding domain 1 protein
EO946_06680	COG1388	LysM domain
EO946_06690	COG4195	phage-related replication protein
EO946_06695	COG3546	catalase activity
EO946_06700	COG2856	Zn peptidase
EO946_06705	COG1396	sequence-specific DNA binding
EO946_06715	COG1522	sequence-specific DNA binding
EO946_06720	COG1484	DNA-dependent DNA replication
EO946_06740	COG1595	DNA-templated transcription, initiation
EO946_06745	COG3728	DNA packaging
EO946_06745	COG5484	DNA packaging
EO946_06750	COG1783	phage Terminase large subunit
EO946_06755	COG5518	Phage portal protein
EO946_06760	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EO946_06765	COG4653	Phage capsid family
EO946_06815	COG5412	phage tail tape measure protein
EO946_06815	COG3953	SLT domain
EO946_06815	COG5412	phage tail tape measure protein
EO946_06815	COG5412	phage tail tape measure protein
EO946_06815	COG3953	SLT domain
EO946_06815	COG3953	SLT domain
EO946_06820	COG1652	LysM domain
EO946_06825	COG4193	domain, Protein
EO946_06835	COG3628	GPW Gp25 family protein
EO946_06840	COG3299	homolog of phage Mu protein gp47
EO946_06845	COG3778	Protein conserved in bacteria
EO946_06885	COG5632	N-Acetylmuramoyl-L-alanine amidase
EO946_06885	COG3409	Peptidoglycan-binding domain 1 protein
EO946_06905	COG0306	phosphate transporter
EO946_06910	COG1392	Phosphate transport regulator
EO946_06915	COG0531	amino acid
EO946_06920	COG0346	lactoylglutathione lyase activity
EO946_06930	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EO946_06935	COG0463	Glycosyl transferase, family 2
EO946_06940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EO946_06945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EO946_06950	COG2362	D-Aminopeptidase
EO946_06955	COG0601	transmembrane transport
EO946_06960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EO946_06965	COG0444	Belongs to the ABC transporter superfamily
EO946_06970	COG4166	transmembrane transport
EO946_06975	COG1619	proteins homologs of microcin C7 resistance protein MccF
EO946_06980	COG4948	Mandelate Racemase Muconate Lactonizing
EO946_06985	COG0791	NLP P60 protein
EO946_06990	COG4608	Belongs to the ABC transporter superfamily
EO946_06995	COG2706	6-phosphogluconolactonase activity
EO946_07000	COG1834	amidinotransferase
EO946_07005	COG1607	acyl-coa hydrolase
EO946_07010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EO946_07010	COG1017	nitric oxide dioxygenase activity
EO946_07020	COG2323	membrane
EO946_07025	COG2318	DinB family
EO946_07030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EO946_07035	COG2076	Multidrug Resistance protein
EO946_07040	COG2076	Multidrug Resistance protein
EO946_07045	COG0788	formyltetrahydrofolate deformylase activity
EO946_07050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EO946_07055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EO946_07060	COG1764	response to oxidative stress
EO946_07065	COG1846	Transcriptional regulator
EO946_07070	COG1764	response to oxidative stress
EO946_07075	COG0457	Tetratricopeptide repeat
EO946_07075	COG0463	Glycosyl transferase, family 2
EO946_07080	COG0590	tRNA wobble adenosine to inosine editing
EO946_07090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EO946_07095	COG1404	Belongs to the peptidase S8 family
EO946_07100	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_07105	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EO946_07110	COG1122	ATPase activity
EO946_07115	COG4721	ABC-type cobalt transport system, permease component
EO946_07125	COG0745	RESPONSE REGULATOR receiver
EO946_07130	COG3850	Histidine kinase
EO946_07130	COG5002	protein histidine kinase activity
EO946_07135	COG3212	peptidase
EO946_07140	COG3212	peptidase
EO946_07150	COG2239	Acts as a magnesium transporter
EO946_07155	COG0789	Transcriptional regulator
EO946_07170	COG1846	Transcriptional regulator
EO946_07175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EO946_07180	COG0726	polysaccharide deacetylase
EO946_07185	COG1408	metallophosphoesterase
EO946_07195	COG0463	Glycosyl transferase, family 2
EO946_07200	COG3285	dna ligase
EO946_07200	COG1793	dna ligase
EO946_07205	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EO946_07210	COG3300	MHYT domain
EO946_07210	COG5001	Diguanylate cyclase
EO946_07215	COG0586	Pfam SNARE associated Golgi protein
EO946_07220	COG0861	Integral membrane protein TerC family
EO946_07225	COG1191	sigma factor activity
EO946_07245	COG0501	Belongs to the peptidase M48B family
EO946_07250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EO946_07265	COG3594	Acyltransferase
EO946_07270	COG5002	protein histidine kinase activity
EO946_07275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EO946_07285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EO946_07290	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EO946_07295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EO946_07300	COG0436	Aminotransferase
EO946_07305	COG1850	ribulose-bisphosphate carboxylase activity
EO946_07310	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EO946_07315	COG0235	Class ii aldolase
EO946_07320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EO946_07325	COG3339	Conserved Protein
EO946_07340	COG3852	Histidine kinase
EO946_07350	COG1846	Transcriptional regulator
EO946_07355	COG1360	Flagellar Motor Protein
EO946_07360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EO946_07365	COG0542	response to heat
EO946_07370	COG3949	Membrane
EO946_07375	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EO946_07380	COG0720	synthase
EO946_07385	COG0602	queuosine metabolic process
EO946_07390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EO946_07405	COG4873	Protein conserved in bacteria
EO946_07415	COG3773	Cell wall hydrolase
EO946_07420	COG2244	polysaccharide biosynthetic process
EO946_07425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_07430	COG2217	Heavy metal translocating P-type atpase
EO946_07440	COG0006	proline dipeptidase activity
EO946_07445	COG1609	Transcriptional regulator
EO946_07450	COG3711	transcriptional antiterminator
EO946_07455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_07455	COG1263	PTS System
EO946_07455	COG2190	(PTS) system
EO946_07460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EO946_07465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EO946_07475	COG1533	DNA photolyase activity
EO946_07480	COG0456	acetyltransferase
EO946_07485	COG0840	transmembrane signaling receptor activity
EO946_07490	COG2084	Dehydrogenase
EO946_07495	COG2340	Cysteine-rich secretory protein family
EO946_07500	COG0768	penicillin binding
EO946_07505	COG4191	Histidine kinase
EO946_07510	COG0436	Aminotransferase
EO946_07520	COG0835	chemotaxis
EO946_07520	COG0784	Response regulator, receiver
EO946_07530	COG2814	Major facilitator Superfamily
EO946_07535	COG1376	ErfK ybiS ycfS ynhG family protein
EO946_07540	COG1408	metallophosphoesterase
EO946_07545	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_07550	COG2200	EAL domain
EO946_07555	COG4703	Protein of unknown function (DUF1797)
EO946_07560	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EO946_07570	COG0517	IMP dehydrogenase activity
EO946_07575	COG0583	DNA-binding transcription factor activity
EO946_07580	COG0716	FMN binding
EO946_07590	COG0716	FMN binding
EO946_07595	COG2171	N-acyltransferase activity
EO946_07600	COG1473	amidohydrolase
EO946_07610	COG0668	transmembrane transport
EO946_07615	COG0450	alkyl hydroperoxide reductase
EO946_07620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_07635	COG0746	molybdenum cofactor guanylyltransferase activity
EO946_07640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EO946_07645	COG0303	'Molybdopterin
EO946_07650	COG1763	Mo-molybdopterin cofactor biosynthetic process
EO946_07655	COG0314	molybdopterin synthase activity
EO946_07660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EO946_07665	COG1132	(ABC) transporter
EO946_07670	COG1132	(ABC) transporter
EO946_07680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EO946_07685	COG1136	(ABC) transporter
EO946_07690	COG0577	efflux transmembrane transporter activity
EO946_07695	COG1349	DNA-binding transcription factor activity
EO946_07700	COG1105	Belongs to the carbohydrate kinase PfkB family
EO946_07705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EO946_07705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EO946_07705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EO946_07715	COG0681	Belongs to the peptidase S26 family
EO946_07725	COG0488	(ABC) transporter
EO946_07730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EO946_07735	COG2309	aminopeptidase activity
EO946_07745	COG1077	Cell shape determining protein MreB Mrl
EO946_07750	COG2002	toxin-antitoxin pair type II binding
EO946_07755	COG3852	Histidine kinase
EO946_07760	COG2105	PFAM AIG2 family protein
EO946_07760	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EO946_07765	COG0569	domain protein
EO946_07770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EO946_07775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EO946_07785	COG0561	phosphatase activity
EO946_07790	COG0242	peptide deformylase activity
EO946_07800	COG0497	DNA recombination
EO946_07805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EO946_07810	COG0022	dehydrogenase e1 component
EO946_07815	COG0508	dehydrogenase complex catalyzes the overall conversion of
EO946_07820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EO946_07825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_07840	COG1982	Orn Lys Arg decarboxylase major
EO946_07845	COG4476	Belongs to the UPF0223 family
EO946_07850	COG4493	Belongs to the UPF0637 family
EO946_07860	COG0483	inositol monophosphate 1-phosphatase activity
EO946_07870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EO946_07890	COG1595	DNA-templated transcription, initiation
EO946_07920	COG4896	Protein conserved in bacteria
EO946_07930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EO946_07935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EO946_07940	COG2066	Belongs to the glutaminase family
EO946_07945	COG4838	Belongs to the UPF0358 family
EO946_07950	COG0772	Belongs to the SEDS family
EO946_07955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EO946_07960	COG1612	heme a metabolic process
EO946_07965	COG0109	protoheme IX farnesyltransferase activity
EO946_07970	COG2010	Cytochrome c
EO946_07970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EO946_07975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EO946_07980	COG1845	cytochrome c oxidase, subunit III
EO946_07985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EO946_07990	COG3336	cytochrome c oxidase
EO946_08000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EO946_08005	COG2340	Cysteine-rich secretory protein family
EO946_08020	COG3679	Belongs to the UPF0342 family
EO946_08025	COG4471	UPF0298 protein
EO946_08030	COG0742	ribosomal rna small subunit methyltransferase
EO946_08035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EO946_08040	COG3314	Sporulation integral membrane protein YlbJ
EO946_08045	COG1752	Esterase of the alpha-beta hydrolase superfamily
EO946_08050	COG3480	Lon protease (S16) C-terminal proteolytic domain
EO946_08055	COG1323	Belongs to the UPF0348 family
EO946_08060	COG1399	metal-binding, possibly nucleic acid-binding protein
EO946_08065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EO946_08075	COG0454	-acetyltransferase
EO946_08080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EO946_08085	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EO946_08090	COG2001	Belongs to the MraZ family
EO946_08095	COG0275	rRNA processing
EO946_08100	COG4839	cell division protein FtsL
EO946_08110	COG0768	penicillin binding
EO946_08115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EO946_08120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EO946_08125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EO946_08130	COG0772	Belongs to the SEDS family
EO946_08135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EO946_08140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EO946_08145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EO946_08150	COG3879	Bacterial protein of unknown function (DUF881)
EO946_08155	COG3879	Bacterial protein of unknown function (DUF881)
EO946_08160	COG3856	small basic protein
EO946_08165	COG0849	cell division
EO946_08170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EO946_08175	COG1404	Belongs to the peptidase S8 family
EO946_08175	COG4412	M6 family metalloprotease domain protein
EO946_08185	COG1191	sigma factor activity
EO946_08190	COG1191	sigma factor activity
EO946_08195	COG1119	ATPase activity
EO946_08200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EO946_08205	COG1873	PFAM PRC-barrel domain
EO946_08215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EO946_08220	COG1799	cell septum assembly
EO946_08225	COG0762	integral membrane protein
EO946_08230	COG2302	S4 RNA-binding domain
EO946_08235	COG3599	regulation of cell shape
EO946_08240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EO946_08245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EO946_08250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EO946_08255	COG0564	pseudouridine synthase activity
EO946_08260	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EO946_08265	COG2233	PERMEase
EO946_08270	COG0540	Belongs to the ATCase OTCase family
EO946_08275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EO946_08280	COG0505	Belongs to the CarA family
EO946_08285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EO946_08290	COG0543	2 iron, 2 sulfur cluster binding
EO946_08295	COG0167	dihydroorotate dehydrogenase activity
EO946_08300	COG0284	orotidine-5'-phosphate decarboxylase activity
EO946_08305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EO946_08310	COG0175	sulfate reduction
EO946_08315	COG0306	phosphate transporter
EO946_08320	COG2046	Belongs to the sulfate adenylyltransferase family
EO946_08325	COG0529	Catalyzes the synthesis of activated sulfate
EO946_08330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EO946_08335	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EO946_08340	COG1648	precorrin-2 dehydrogenase activity
EO946_08350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EO946_08355	COG1561	YicC-like family, N-terminal region
EO946_08360	COG2052	Domain of unknown function (DUF370)
EO946_08365	COG0194	GDP metabolic process
EO946_08370	COG1758	RNA polymerase activity
EO946_08375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EO946_08380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EO946_08385	COG0242	peptide deformylase activity
EO946_08390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EO946_08395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EO946_08395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EO946_08400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EO946_08405	COG0631	protein serine/threonine phosphatase activity
EO946_08410	COG2815	serine threonine protein kinase
EO946_08410	COG0515	serine threonine protein kinase
EO946_08415	COG1162	GTPase activity
EO946_08420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EO946_08425	COG1564	THIamine pyrophosphokinase
EO946_08435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EO946_08440	COG1302	Protein conserved in bacteria
EO946_08445	COG1461	Dihydroxyacetone kinase
EO946_08450	COG1760	l-serine dehydratase
EO946_08455	COG1760	l-serine dehydratase
EO946_08460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EO946_08465	COG2050	protein possibly involved in aromatic compounds catabolism
EO946_08465	COG1349	DNA-binding transcription factor activity
EO946_08470	COG0416	fatty acid biosynthetic process
EO946_08475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EO946_08480	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_08485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EO946_08490	COG0571	ribonuclease III activity
EO946_08495	COG1196	nuclear chromosome segregation
EO946_08500	COG0552	protein localization to endoplasmic reticulum
EO946_08515	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EO946_08520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EO946_08525	COG0228	four-way junction DNA binding
EO946_08530	COG1837	Belongs to the UPF0109 family
EO946_08540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EO946_08545	COG0336	Belongs to the RNA methyltransferase TrmD family
EO946_08550	COG0335	large ribosomal subunit rRNA binding
EO946_08560	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EO946_08570	COG2257	FlhB HrpN YscU SpaS Family
EO946_08575	COG0045	succinate-CoA ligase (ADP-forming) activity
EO946_08580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EO946_08585	COG0758	DNA mediated transformation
EO946_08590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EO946_08595	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EO946_08600	COG4974	Belongs to the 'phage' integrase family
EO946_08605	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EO946_08615	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EO946_08620	COG1815	bacterial-type flagellum-dependent cell motility
EO946_08625	COG1558	bacterial-type flagellum-dependent cell motility
EO946_08630	COG1677	Flagellar hook-basal body complex protein FliE
EO946_08635	COG1766	The M ring may be actively involved in energy transduction
EO946_08640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EO946_08645	COG1317	bacterial-type flagellum organization
EO946_08650	COG1157	protein secretion by the type III secretion system
EO946_08655	COG2882	bacterial-type flagellum organization
EO946_08660	COG3334	PFAM MgtE intracellular
EO946_08665	COG3144	bacterial-type flagellum assembly
EO946_08670	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EO946_08675	COG4786	Flagellar basal body rod
EO946_08680	COG1582	Flagellar protein (FlbD)
EO946_08685	COG1580	Controls the rotational direction of flagella during chemotaxis
EO946_08690	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EO946_08695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EO946_08695	COG1776	CheC inhibitor of MCP methylation
EO946_08700	COG2201	protein-glutamate methylesterase activity
EO946_08705	COG3190	flagellar
EO946_08710	COG1338	Plays a role in the flagellum-specific transport system
EO946_08715	COG1987	bacterial-type flagellum assembly
EO946_08720	COG1684	flagellar biosynthetic protein fliR
EO946_08725	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EO946_08730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EO946_08735	COG1419	protein localization to endoplasmic reticulum
EO946_08740	COG0455	bacterial-type flagellum organization
EO946_08745	COG2201	protein-glutamate methylesterase activity
EO946_08750	COG0643	Histidine kinase
EO946_08750	COG2198	Histidine kinase
EO946_08755	COG0835	chemotaxis
EO946_08760	COG1776	CheC inhibitor of MCP methylation
EO946_08765	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EO946_08770	COG1191	sigma factor activity
EO946_08780	COG0052	Belongs to the universal ribosomal protein uS2 family
EO946_08785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EO946_08790	COG0528	UMP kinase activity
EO946_08795	COG0233	cytoplasmic translational termination
EO946_08800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EO946_08805	COG4589	Belongs to the CDS family
EO946_08810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EO946_08815	COG0750	zinc metalloprotease
EO946_08820	COG0442	prolyl-tRNA aminoacylation
EO946_08825	COG2176	DNA-directed DNA polymerase activity
EO946_08830	COG0779	Required for maturation of 30S ribosomal subunits
EO946_08835	COG0195	Participates in both transcription termination and antitermination
EO946_08840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EO946_08845	COG1358	cellular component organization or biogenesis
EO946_08850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EO946_08855	COG1550	Protein conserved in bacteria
EO946_08860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EO946_08865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EO946_08870	COG0196	riboflavin kinase activity
EO946_08875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EO946_08880	COG1185	polyribonucleotide nucleotidyltransferase activity
EO946_08885	COG0726	polysaccharide deacetylase
EO946_08890	COG0612	Peptidase, M16
EO946_08895	COG1873	PFAM PRC-barrel domain
EO946_08900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EO946_08905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EO946_08910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EO946_08915	COG0527	aspartate kinase activity
EO946_08920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EO946_08925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EO946_08930	COG0740	serine-type endopeptidase activity
EO946_08940	COG1674	ftsk spoiiie
EO946_08940	COG4980	gas vesicle protein
EO946_08945	COG2188	Transcriptional regulator
EO946_08950	COG2814	Major facilitator Superfamily
EO946_08955	COG0612	Peptidase, M16
EO946_08960	COG0612	Peptidase, M16
EO946_08965	COG0300	oxidoreductase activity
EO946_08980	COG1426	Protein conserved in bacteria
EO946_08985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EO946_08990	COG1546	Belongs to the CinA family
EO946_08990	COG1058	Belongs to the CinA family
EO946_08995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EO946_09000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EO946_09005	COG1418	mRNA catabolic process
EO946_09010	COG1692	metallophosphoesterase
EO946_09015	COG2359	stage V sporulation protein S
EO946_09020	COG1063	alcohol dehydrogenase
EO946_09025	COG0156	8-amino-7-oxononanoate synthase activity
EO946_09030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EO946_09035	COG4550	Control of competence regulator ComK, YlbF/YmcA
EO946_09045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EO946_09050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EO946_09070	COG3226	Transcriptional regulator
EO946_09075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EO946_09085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EO946_09090	COG3321	synthase
EO946_09095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EO946_09095	COG2070	2-Nitropropane dioxygenase
EO946_09100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EO946_09105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EO946_09110	COG3425	synthase
EO946_09115	COG1024	Enoyl-CoA hydratase
EO946_09120	COG1024	Enoyl-CoA hydratase
EO946_09125	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_09125	COG3321	synthase
EO946_09125	COG0300	oxidoreductase activity
EO946_09125	COG0318	PFAM AMP-dependent synthetase and ligase
EO946_09125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_09130	COG4221	oxidoreductase activity
EO946_09130	COG3321	synthase
EO946_09130	COG0300	oxidoreductase activity
EO946_09130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EO946_09135	COG3321	synthase
EO946_09135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EO946_09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EO946_09135	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_09135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_09140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_09140	COG4221	oxidoreductase activity
EO946_09140	COG3321	synthase
EO946_09140	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_09145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EO946_09145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EO946_09145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EO946_09145	COG3321	synthase
EO946_09150	COG2124	cytochrome p450
EO946_09160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EO946_09165	COG1404	Belongs to the peptidase S8 family
EO946_09175	COG4195	phage-related replication protein
EO946_09180	COG1764	response to oxidative stress
EO946_09205	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EO946_09210	COG1923	regulation of RNA biosynthetic process
EO946_09225	COG1780	Probably involved in ribonucleotide reductase function
EO946_09230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EO946_09235	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EO946_09240	COG4112	unkown
EO946_09245	COG0860	N-Acetylmuramoyl-L-alanine amidase
EO946_09255	COG0464	growth
EO946_09260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EO946_09265	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EO946_09270	COG0789	Transcriptional regulator
EO946_09275	COG0174	glutamine synthetase
EO946_09300	COG2211	Major facilitator Superfamily
EO946_09305	COG3507	Belongs to the glycosyl hydrolase 43 family
EO946_09320	COG1070	Carbohydrate kinase
EO946_09335	COG2814	Major facilitator Superfamily
EO946_09340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EO946_09350	COG0756	dUTP diphosphatase activity
EO946_09400	COG3832	glyoxalase III activity
EO946_09415	COG2059	Chromate
EO946_09445	COG4195	phage-related replication protein
EO946_09455	COG0346	lactoylglutathione lyase activity
EO946_09470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EO946_09475	COG1388	LysM domain
EO946_09480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EO946_09485	COG4224	UPF0291 protein
EO946_09490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EO946_09500	COG3763	UPF0154 protein
EO946_09510	COG0785	Cytochrome C biogenesis protein
EO946_09515	COG2201	protein-glutamate methylesterase activity
EO946_09520	COG4846	Membrane protein involved in cytochrome C biogenesis
EO946_09530	COG0071	Belongs to the small heat shock protein (HSP20) family
EO946_09545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EO946_09550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_09570	COG0824	Thioesterase
EO946_09580	COG4841	protein insertion into membrane
EO946_09585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EO946_09590	COG1832	CoA-binding protein
EO946_09595	COG0187	DNA topoisomerase II activity
EO946_09600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EO946_09610	COG1115	amino acid carrier protein
EO946_09615	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EO946_09625	COG2246	polysaccharide biosynthetic process
EO946_09630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EO946_09635	COG0586	Pfam SNARE associated Golgi protein
EO946_09670	COG2404	hydrolase activity, acting on ester bonds
EO946_09675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EO946_09680	COG1024	Enoyl-CoA hydratase
EO946_09685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EO946_09690	COG0511	ligase activity, forming carbon-carbon bonds
EO946_09695	COG0439	Biotin carboxylase
EO946_09700	COG0318	PFAM AMP-dependent synthetase and ligase
EO946_09705	COG1960	acyl-CoA dehydrogenase activity
EO946_09720	COG1649	PFAM Uncharacterised BCR, COG1649
EO946_09750	COG2027	D-alanyl-D-alanine carboxypeptidase
EO946_09755	COG2017	converts alpha-aldose to the beta-anomer
EO946_09760	COG0534	Mate efflux family protein
EO946_09785	COG5632	N-Acetylmuramoyl-L-alanine amidase
EO946_09785	COG1388	LysM domain
EO946_09785	COG3409	Peptidoglycan-binding domain 1 protein
EO946_09825	COG1705	Flagellar rod assembly protein muramidase FlgJ
EO946_09825	COG3942	CHAP domain
EO946_09940	COG0582	viral genome integration into host DNA
EO946_10045	COG0582	viral genome integration into host DNA
EO946_10050	COG0166	Belongs to the GPI family
EO946_10055	COG0405	Gamma-glutamyltransferase
EO946_10070	COG0493	'glutamate synthase
EO946_10075	COG0070	glutamate synthase
EO946_10075	COG0069	glutamate synthase activity
EO946_10075	COG0067	glutamate synthase
EO946_10080	COG0583	DNA-binding transcription factor activity
EO946_10085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EO946_10105	COG0300	oxidoreductase activity
EO946_10110	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EO946_10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EO946_10145	COG2814	Major facilitator Superfamily
EO946_10150	COG1070	Carbohydrate kinase
EO946_10155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EO946_10160	COG0243	molybdopterin cofactor binding
EO946_10190	COG5278	phosphoserine phosphatase activity
EO946_10190	COG0840	transmembrane signaling receptor activity
EO946_10195	COG2368	4-hydroxyphenylacetate
EO946_10200	COG4305	rare lipoprotein A
EO946_10205	COG3619	membrane
EO946_10230	COG2135	peptidase activity
EO946_10270	COG2720	vancomycin resistance protein
EO946_10280	COG3655	Transcriptional regulator
EO946_10285	COG3739	integral membrane protein
EO946_10290	COG0583	DNA-binding transcription factor activity
EO946_10295	COG0697	spore germination
EO946_10320	COG0693	protein deglycase activity
EO946_10325	COG2367	Beta-lactamase
EO946_10335	COG3397	chitin binding
EO946_10340	COG2318	DinB family
EO946_10345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EO946_10365	COG1215	transferase activity, transferring glycosyl groups
EO946_10410	COG4974	Belongs to the 'phage' integrase family
EO946_10430	COG2273	Hydrolase Family 16
EO946_10440	COG4282	regulation of fungal-type cell wall biogenesis
EO946_10445	COG1231	oxidoreductase activity
EO946_10450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EO946_10455	COG2207	Transcriptional regulator
EO946_10455	COG0662	Cupin 2, conserved barrel domain protein
EO946_10460	COG0456	acetyltransferase
EO946_10465	COG1309	transcriptional regulator
EO946_10475	COG3708	Transcriptional regulator
EO946_10480	COG2378	regulation of single-species biofilm formation
EO946_10490	COG0640	Transcriptional regulator
EO946_10495	COG0741	lytic transglycosylase activity
EO946_10500	COG2322	membrane
EO946_10515	COG1619	proteins homologs of microcin C7 resistance protein MccF
EO946_10520	COG3239	Fatty acid desaturase
EO946_10525	COG4585	Histidine kinase
EO946_10530	COG2197	response regulator
EO946_10535	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EO946_10540	COG3584	3D domain protein
EO946_10540	COG1388	LysM domain
EO946_10545	COG0514	ATP-dependent DNA helicase (RecQ)
EO946_10555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EO946_10560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EO946_10575	COG1012	belongs to the aldehyde dehydrogenase family
EO946_10580	COG1657	PFAM Prenyltransferase squalene oxidase
EO946_10585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EO946_10590	COG0733	neurotransmitter:sodium symporter activity
EO946_10595	COG0385	Bile acid
EO946_10600	COG0508	dehydrogenase complex catalyzes the overall conversion of
EO946_10605	COG0567	Dehydrogenase, E1 component
EO946_10610	COG4548	von Willebrand factor, type A
EO946_10615	COG0714	Associated with various cellular activities
EO946_10620	COG2032	superoxide dismutase activity
EO946_10625	COG1388	LysM domain
EO946_10625	COG0791	NLP P60 protein
EO946_10630	COG1819	glycosyl
EO946_10635	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EO946_10640	COG0534	Mate efflux family protein
EO946_10645	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_10650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EO946_10655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EO946_10665	COG2962	Rard protein
EO946_10680	COG1942	4-Oxalocrotonate Tautomerase
EO946_10690	COG1733	regulation of RNA biosynthetic process
EO946_10695	COG0778	Nitroreductase
EO946_10700	COG0400	carboxylic ester hydrolase activity
EO946_10715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EO946_10720	COG0793	Belongs to the peptidase S41A family
EO946_10720	COG3409	Peptidoglycan-binding domain 1 protein
EO946_10725	COG2226	methyltransferase
EO946_10735	COG1876	peptidase activity
EO946_10740	COG0813	purine-nucleoside phosphorylase activity
EO946_10755	COG0671	phosphoesterase, PA-phosphatase related
EO946_10780	COG4479	Belongs to the UPF0346 family
EO946_10790	COG1509	lysine 2,3-aminomutase activity
EO946_10795	COG0456	acetyltransferase
EO946_10800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EO946_10805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EO946_10810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EO946_10815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EO946_10830	COG0456	acetyltransferase
EO946_10835	COG0463	Glycosyl transferase, family 2
EO946_10850	COG4641	Protein conserved in bacteria
EO946_10855	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
EO946_10860	COG1086	Polysaccharide biosynthesis protein
EO946_10865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EO946_10870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EO946_10875	COG1846	Transcriptional regulator
EO946_10880	COG0534	Mate efflux family protein
EO946_10890	COG4698	Protein conserved in bacteria
EO946_10895	COG2755	lipolytic protein G-D-S-L family
EO946_10900	COG1999	signal sequence binding
EO946_10910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EO946_10915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EO946_10920	COG1272	protein, Hemolysin III
EO946_10925	COG0204	Acyl-transferase
EO946_10930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EO946_10940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EO946_10950	COG2136	Putative SAM-dependent methyltransferase
EO946_10950	COG2521	methyltransferase
EO946_10960	COG0129	dihydroxy-acid dehydratase activity
EO946_10965	COG1413	lyase activity
EO946_10970	COG1418	mRNA catabolic process
EO946_10975	COG0386	Belongs to the glutathione peroxidase family
EO946_10980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EO946_10985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EO946_10995	COG1278	Cold shock
EO946_11015	COG0328	RNA-DNA hybrid ribonuclease activity
EO946_11020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EO946_11025	COG0328	RNA-DNA hybrid ribonuclease activity
EO946_11035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EO946_11050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EO946_11060	COG1755	Isoprenylcysteine carboxyl methyltransferase
EO946_11065	COG3424	synthase
EO946_11070	COG2233	PERMEase
EO946_11075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EO946_11080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EO946_11090	COG0800	Aldolase
EO946_11095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EO946_11100	COG1609	Transcriptional regulator
EO946_11105	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EO946_11110	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_11115	COG1199	ATP-dependent helicase activity
EO946_11130	COG0116	Belongs to the methyltransferase superfamily
EO946_11145	COG4474	Belongs to the UPF0398 family
EO946_11160	COG3359	exonuclease
EO946_11165	COG1111	helicase
EO946_11165	COG1205	dead DEAH box helicase
EO946_11170	COG2190	(PTS) system
EO946_11175	COG0071	Belongs to the small heat shock protein (HSP20) family
EO946_11210	COG3331	DNA recombination
EO946_11215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EO946_11215	COG4499	WXG100 protein secretion system (Wss), protein YukC
EO946_11225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EO946_11230	COG3935	DnaD domain protein
EO946_11235	COG0017	Asparaginyl-tRNA synthetase
EO946_11240	COG0436	Aminotransferase
EO946_11245	COG5353	protein conserved in bacteria
EO946_11255	COG1199	ATP-dependent helicase activity
EO946_11255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EO946_11260	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EO946_11265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EO946_11270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EO946_11280	COG0617	tRNA 3'-terminal CCA addition
EO946_11285	COG0438	transferase activity, transferring glycosyl groups
EO946_11290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EO946_11295	COG1803	Methylglyoxal synthase
EO946_11300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EO946_11305	COG1694	Mazg nucleotide pyrophosphohydrolase
EO946_11310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EO946_11320	COG4347	Protein of unknown function (DUF1405)
EO946_11325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EO946_11325	COG2010	Cytochrome c
EO946_11330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EO946_11335	COG0723	plastoquinol--plastocyanin reductase activity
EO946_11345	COG5582	Belongs to the UPF0302 family
EO946_11350	COG0457	Tetratricopeptide repeat
EO946_11360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EO946_11365	COG0287	Prephenate dehydrogenase
EO946_11370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EO946_11375	COG0159	tryptophan synthase activity
EO946_11380	COG0133	tryptophan synthase activity
EO946_11385	COG0135	phosphoribosylanthranilate isomerase activity
EO946_11395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EO946_11400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EO946_11405	COG4401	Chorismate mutase type I
EO946_11410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EO946_11415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EO946_11420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EO946_11425	COG0105	UTP biosynthetic process
EO946_11430	COG0142	geranyltranstransferase activity
EO946_11435	COG2226	methyltransferase
EO946_11440	COG0142	geranyltranstransferase activity
EO946_11450	COG0302	gtp cyclohydrolase
EO946_11455	COG0776	regulation of translation
EO946_11460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EO946_11475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EO946_11480	COG1160	GTP binding
EO946_11505	COG1304	FMN binding
EO946_11510	COG0539	negative regulation of cytoplasmic translation
EO946_11515	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EO946_11525	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EO946_11530	COG2959	enzyme of heme biosynthesis
EO946_11535	COG3409	Peptidoglycan-binding domain 1 protein
EO946_11535	COG3773	Cell wall hydrolase
EO946_11540	COG2339	peptidase activity
EO946_11545	COG0492	ferredoxin-NADP+ reductase activity
EO946_11550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EO946_11555	COG4862	establishment of competence for transformation
EO946_11560	COG1408	metallophosphoesterase
EO946_11570	COG1388	LysM domain
EO946_11575	COG1266	CAAX protease self-immunity
EO946_11580	COG0514	ATP-dependent DNA helicase (RecQ)
EO946_11585	COG4955	Helix-turn-helix domain
EO946_11590	COG1141	Ferredoxin
EO946_11595	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EO946_11600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EO946_11605	COG0710	3-dehydroquinate dehydratase activity
EO946_11615	COG1595	DNA-templated transcription, initiation
EO946_11620	COG5002	protein histidine kinase activity
EO946_11625	COG0745	RESPONSE REGULATOR receiver
EO946_11630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EO946_11635	COG1333	cytochrome c biogenesis protein
EO946_11640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_11645	COG1187	pseudouridine synthase activity
EO946_11650	COG0700	Nucleoside recognition
EO946_11655	COG2715	membrane protein required for spore maturation
EO946_11660	COG1686	Belongs to the peptidase S11 family
EO946_11670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EO946_11675	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EO946_11680	COG1547	Domain of unknown function (DUF309)
EO946_11685	COG0456	acetyltransferase
EO946_11690	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EO946_11695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EO946_11695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EO946_11700	COG0307	riboflavin synthase, alpha
EO946_11705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EO946_11705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EO946_11715	COG0681	Belongs to the peptidase S26 family
EO946_11725	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EO946_11735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EO946_11745	COG4086	secreted protein
EO946_11750	COG0019	diaminopimelate decarboxylase activity
EO946_11755	COG0697	spore germination
EO946_11770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EO946_11790	COG1191	sigma factor activity
EO946_11795	COG2172	sigma factor antagonist activity
EO946_11800	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_11805	COG1686	Belongs to the peptidase S11 family
EO946_11810	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EO946_11815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EO946_11820	COG4974	Belongs to the 'phage' integrase family
EO946_11830	COG0735	belongs to the Fur family
EO946_11835	COG1300	Membrane
EO946_11845	COG0281	malic enzyme
EO946_11850	COG1757	Na H antiporter
EO946_11855	COG1027	Aspartate ammonia-lyase
EO946_11860	COG0252	asparaginase activity
EO946_11865	COG1396	sequence-specific DNA binding
EO946_11885	COG0494	nUDIX hydrolase
EO946_11895	COG0667	Aldo Keto reductase
EO946_11905	COG1073	alpha beta
EO946_11910	COG0772	Belongs to the SEDS family
EO946_11915	COG0772	Belongs to the SEDS family
EO946_11920	COG3339	Conserved Protein
EO946_11930	COG4918	Iron-sulphur cluster biosynthesis
EO946_11935	COG0456	acetyltransferase
EO946_11935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EO946_11940	COG2329	Antibiotic biosynthesis monooxygenase
EO946_11945	COG0456	acetyltransferase
EO946_11955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EO946_11970	COG2211	Major facilitator Superfamily
EO946_11975	COG0346	lactoylglutathione lyase activity
EO946_11980	COG1072	(Pantothenic acid kinase))
EO946_11985	COG3048	D-serine ammonia-lyase activity
EO946_11990	COG0300	oxidoreductase activity
EO946_11995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EO946_12000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EO946_12005	COG4187	Peptidase family M20/M25/M40
EO946_12010	COG1902	pentaerythritol trinitrate reductase activity
EO946_12015	COG0596	Alpha beta hydrolase
EO946_12030	COG1234	tRNA 3'-trailer cleavage
EO946_12035	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EO946_12040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EO946_12045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EO946_12055	COG0706	membrane insertase activity
EO946_12060	COG3361	conserved protein (COG2071)
EO946_12065	COG2195	Cleaves the N-terminal amino acid of tripeptides
EO946_12070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EO946_12075	COG0346	lactoylglutathione lyase activity
EO946_12080	COG1376	ErfK ybiS ycfS ynhG family protein
EO946_12085	COG4129	membrane
EO946_12090	COG1126	abc transporter atp-binding protein
EO946_12095	COG0765	amino acid transport
EO946_12100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EO946_12110	COG1597	lipid kinase activity
EO946_12115	COG2814	Major facilitator Superfamily
EO946_12120	COG0789	Transcriptional regulator
EO946_12120	COG4978	Transcriptional regulator
EO946_12125	COG0508	dehydrogenase complex catalyzes the overall conversion of
EO946_12130	COG0022	dehydrogenase e1 component
EO946_12135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EO946_12140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EO946_12145	COG3426	butyrate kinase activity
EO946_12150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EO946_12155	COG0280	phosphate acetyltransferase
EO946_12160	COG3829	transcription factor binding
EO946_12160	COG3290	protein histidine kinase activity
EO946_12170	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EO946_12175	COG2079	MmgE PrpD family protein
EO946_12180	COG0372	Belongs to the citrate synthase family
EO946_12185	COG1960	acyl-CoA dehydrogenase activity
EO946_12190	COG1250	3-hydroxyacyl-CoA dehydrogenase
EO946_12195	COG0183	Belongs to the thiolase family
EO946_12200	COG0584	glycerophosphoryl diester phosphodiesterase
EO946_12205	COG0860	N-Acetylmuramoyl-L-alanine amidase
EO946_12220	COG1902	pentaerythritol trinitrate reductase activity
EO946_12225	COG0745	RESPONSE REGULATOR receiver
EO946_12235	COG0750	zinc metalloprotease
EO946_12240	COG0497	DNA recombination
EO946_12245	COG1438	arginine binding
EO946_12250	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EO946_12255	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EO946_12260	COG0142	geranyltranstransferase activity
EO946_12265	COG1722	exodeoxyribonuclease VII activity
EO946_12270	COG1570	exodeoxyribonuclease VII activity
EO946_12275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EO946_12280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EO946_12285	COG1302	Protein conserved in bacteria
EO946_12290	COG0439	Biotin carboxylase
EO946_12295	COG0511	ligase activity, forming carbon-carbon bonds
EO946_12335	COG3854	ATPases associated with a variety of cellular activities
EO946_12345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EO946_12350	COG0006	proline dipeptidase activity
EO946_12355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EO946_12365	COG3872	metal-dependent enzyme
EO946_12375	COG1752	Esterase of the alpha-beta hydrolase superfamily
EO946_12380	COG1321	iron dependent repressor
EO946_12385	COG0095	Lipoate-protein ligase
EO946_12390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EO946_12395	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EO946_12400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EO946_12405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EO946_12410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EO946_12430	COG1396	sequence-specific DNA binding
EO946_12440	COG0681	Belongs to the peptidase S26 family
EO946_12465	COG4940	Competence protein ComGF
EO946_12475	COG4970	Tfp pilus assembly protein FimT
EO946_12480	COG4537	Required for transformation and DNA binding
EO946_12485	COG1459	type II secretion system
EO946_12490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EO946_12500	COG0517	IMP dehydrogenase activity
EO946_12505	COG0598	Magnesium transport protein CorA
EO946_12510	COG1253	flavin adenine dinucleotide binding
EO946_12515	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_12525	COG1393	Belongs to the ArsC family
EO946_12535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EO946_12545	COG0011	TIGRFAM Protein of
EO946_12555	COG2866	Carboxypeptidase
EO946_12560	COG1368	sulfuric ester hydrolase activity
EO946_12565	COG1940	carbohydrate kinase activity
EO946_12570	COG4483	Protein conserved in bacteria
EO946_12575	COG0705	Rhomboid family
EO946_12575	COG0457	Tetratricopeptide repeat
EO946_12585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EO946_12590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EO946_12595	COG0438	transferase activity, transferring glycosyl groups
EO946_12610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EO946_12615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EO946_12620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EO946_12625	COG0581	inorganic phosphate transmembrane transporter activity
EO946_12630	COG0573	inorganic phosphate transmembrane transporter activity
EO946_12635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EO946_12645	COG0477	Major facilitator Superfamily
EO946_12650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EO946_12655	COG2839	Protein conserved in bacteria
EO946_12660	COG5521	maltodextrose utilization protein MalA
EO946_12665	COG1388	LysM domain
EO946_12670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EO946_12675	COG4709	membrane
EO946_12680	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EO946_12685	COG0735	belongs to the Fur family
EO946_12690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EO946_12700	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EO946_12705	COG0513	Belongs to the DEAD box helicase family
EO946_12715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EO946_12720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EO946_12725	COG2384	SAM-dependent methyltransferase
EO946_12730	COG2010	Cytochrome c
EO946_12735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EO946_12740	COG0358	DNA primase activity
EO946_12745	COG1671	Belongs to the UPF0178 family
EO946_12750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EO946_12755	COG0517	IMP dehydrogenase activity
EO946_12760	COG0751	glycine-tRNA ligase activity
EO946_12765	COG0752	glycyl-tRNA synthetase alpha subunit
EO946_12770	COG1381	Involved in DNA repair and RecF pathway recombination
EO946_12780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EO946_12785	COG0295	cytidine deaminase activity
EO946_12790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EO946_12795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EO946_12800	COG1480	7TM receptor with intracellular HD hydrolase
EO946_12805	COG1702	phosphate starvation-inducible protein PhoH
EO946_12810	COG0561	phosphatase activity
EO946_12825	COG4864	UPF0365 protein
EO946_12830	COG1030	water channel activity
EO946_12835	COG1610	YqeY-like protein
EO946_12840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EO946_12845	COG1283	sodium-dependent phosphate transmembrane transporter activity
EO946_12850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EO946_12855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EO946_12860	COG2264	protein methyltransferase activity
EO946_12865	COG0484	heat shock protein binding
EO946_12875	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EO946_12880	COG1420	regulation of RNA biosynthetic process
EO946_12885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EO946_12890	COG0481	GTPase activity
EO946_12900	COG0860	N-Acetylmuramoyl-L-alanine amidase
EO946_12905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EO946_12910	COG0268	Binds directly to 16S ribosomal RNA
EO946_12915	COG1466	dna polymerase III delta subunit
EO946_12930	COG0658	competence protein
EO946_12930	COG2333	competence protein COMEC
EO946_12935	COG2131	deaminase
EO946_12940	COG1596	polysaccharide export
EO946_12940	COG1555	photosystem II stabilization
EO946_12945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EO946_12950	COG2226	methyltransferase
EO946_12955	COG0799	negative regulation of ribosome biogenesis
EO946_12960	COG1713	HD superfamily hydrolase involved in NAD metabolism
EO946_12965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EO946_12970	COG1534	Rna-binding protein
EO946_12975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EO946_12980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EO946_12985	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EO946_12995	COG2755	lipolytic protein G-D-S-L family
EO946_13005	COG3409	Peptidoglycan-binding domain 1 protein
EO946_13005	COG5632	N-Acetylmuramoyl-L-alanine amidase
EO946_13010	COG0398	Pfam SNARE associated Golgi protein
EO946_13015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EO946_13025	COG3209	COG3209 Rhs family protein
EO946_13035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EO946_13045	COG0114	fumarate hydratase activity
EO946_13050	COG0583	DNA-binding transcription factor activity
EO946_13070	COG2070	2-Nitropropane dioxygenase
EO946_13075	COG1846	Transcriptional regulator
EO946_13085	COG1733	regulation of RNA biosynthetic process
EO946_13095	COG2207	Transcriptional regulator
EO946_13105	COG4221	oxidoreductase activity
EO946_13110	COG0456	acetyltransferase
EO946_13115	COG0789	Transcriptional regulator
EO946_13115	COG4978	Transcriptional regulator
EO946_13120	COG2814	Major facilitator Superfamily
EO946_13125	COG1183	phosphatidylcholine synthase activity
EO946_13135	COG2186	Transcriptional regulator
EO946_13145	COG0205	6-phosphofructokinase activity
EO946_13150	COG0205	6-phosphofructokinase activity
EO946_13160	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_13165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EO946_13170	COG3959	Transketolase, thiamine diphosphate binding domain
EO946_13185	COG0640	Transcriptional regulator
EO946_13200	COG1115	amino acid carrier protein
EO946_13210	COG2315	Protein conserved in bacteria
EO946_13225	COG3443	Belongs to the bacterial solute-binding protein 9 family
EO946_13230	COG4991	sh3 domain protein
EO946_13235	COG4991	sh3 domain protein
EO946_13245	COG5577	PFAM Coat F domain
EO946_13250	COG1063	alcohol dehydrogenase
EO946_13260	COG5577	PFAM Coat F domain
EO946_13270	COG0667	Aldo Keto reductase
EO946_13275	COG2207	Transcriptional regulator
EO946_13280	COG0789	Transcriptional regulator
EO946_13285	COG0789	Transcriptional regulator
EO946_13290	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EO946_13295	COG1064	alcohol dehydrogenase
EO946_13300	COG0693	protein deglycase activity
EO946_13305	COG1621	beta-fructofuranosidase activity
EO946_13315	COG3716	PTS system mannose fructose sorbose family IID component
EO946_13320	COG3715	PTS system
EO946_13325	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_13330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EO946_13335	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EO946_13335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EO946_13350	COG1113	amino acid transport
EO946_13355	COG1280	lysine exporter protein (LysE YggA)
EO946_13360	COG1378	Sugar-specific transcriptional regulator TrmB
EO946_13365	COG1595	DNA-templated transcription, initiation
EO946_13375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EO946_13375	COG2755	lipolytic protein G-D-S-L family
EO946_13385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EO946_13385	COG2124	cytochrome p450
EO946_13390	COG1309	transcriptional regulator
EO946_13395	COG2226	methyltransferase
EO946_13410	COG2116	formate transmembrane transporter activity
EO946_13415	COG5609	conserved protein (DUF2294)
EO946_13420	COG3383	formate dehydrogenase (NAD+) activity
EO946_13425	COG2427	Protein of unknown function (DUF1641)
EO946_13435	COG0626	cystathionine gamma-synthase activity
EO946_13440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EO946_13445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EO946_13450	COG2226	methyltransferase
EO946_13465	COG0768	penicillin binding
EO946_13470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EO946_13475	COG0572	uridine kinase
EO946_13495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EO946_13500	COG3906	Belongs to the UPF0473 family
EO946_13505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EO946_13510	COG4472	Bacterial protein of unknown function (DUF965)
EO946_13515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EO946_13520	COG0628	permease
EO946_13535	COG3881	PFAM PRC-barrel domain
EO946_13540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EO946_13545	COG0457	Tetratricopeptide repeat
EO946_13550	COG0482	sulfurtransferase activity
EO946_13555	COG1104	cysteine desulfurase activity
EO946_13560	COG1959	2 iron, 2 sulfur cluster binding
EO946_13565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EO946_13575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EO946_13585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EO946_13590	COG0124	histidyl-tRNA synthetase
EO946_13600	COG4991	sh3 domain protein
EO946_13600	COG3103	Sh3 type 3 domain protein
EO946_13600	COG0860	N-Acetylmuramoyl-L-alanine amidase
EO946_13605	COG1490	D-aminoacyl-tRNA deacylase activity
EO946_13610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EO946_13615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EO946_13620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EO946_13620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EO946_13625	COG5416	Lipopolysaccharide assembly protein A domain
EO946_13630	COG0490	domain, Protein
EO946_13635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EO946_13635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EO946_13645	COG2244	polysaccharide biosynthetic process
EO946_13650	COG2323	membrane
EO946_13660	COG1862	Preprotein translocase
EO946_13665	COG0343	queuine tRNA-ribosyltransferase activity
EO946_13670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EO946_13680	COG2255	four-way junction helicase activity
EO946_13685	COG0632	four-way junction helicase activity
EO946_13695	COG2814	Major facilitator Superfamily
EO946_13700	COG0673	inositol 2-dehydrogenase activity
EO946_13705	COG2112	serine threonine protein kinase
EO946_13715	COG1115	amino acid carrier protein
EO946_13720	COG0217	transcriptional regulatory protein
EO946_13730	COG1388	LysM domain
EO946_13735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EO946_13740	COG0157	Belongs to the NadC ModD family
EO946_13745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EO946_13750	COG1104	cysteine desulfurase activity
EO946_13755	COG1827	regulation of RNA biosynthetic process
EO946_13760	COG0077	Prephenate dehydratase
EO946_13765	COG4492	Belongs to the UPF0735 family
EO946_13770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EO946_13775	COG3290	protein histidine kinase activity
EO946_13785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EO946_13790	COG2868	ribosomal protein
EO946_13795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EO946_13800	COG1994	Peptidase M50
EO946_13805	COG0739	heme binding
EO946_13810	COG2894	cell division
EO946_13815	COG0850	regulation of cytokinetic process
EO946_13820	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EO946_13825	COG1792	Involved in formation and maintenance of cell shape
EO946_13830	COG1077	Cell shape determining protein MreB Mrl
EO946_13835	COG2003	Belongs to the UPF0758 family
EO946_13840	COG0424	maF-like protein
EO946_13850	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EO946_13855	COG0285	dihydrofolate synthase activity
EO946_13860	COG0525	valine-tRNA ligase activity
EO946_13870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EO946_13875	COG1388	LysM domain
EO946_13880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EO946_13885	COG0113	porphobilinogen synthase activity
EO946_13890	COG1587	Uroporphyrinogen-III synthase
EO946_13895	COG0181	hydroxymethylbilane synthase activity
EO946_13900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EO946_13905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EO946_13915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EO946_13920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EO946_13925	COG1067	ATP-dependent peptidase activity
EO946_13925	COG0470	DNA polymerase III
EO946_13930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EO946_13935	COG0544	peptidyl-prolyl cis-trans isomerase activity
EO946_13940	COG1477	protein flavinylation
EO946_13940	COG0457	Tetratricopeptide repeat
EO946_13945	COG0066	3-isopropylmalate dehydratase activity
EO946_13950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EO946_13955	COG0473	3-isopropylmalate dehydrogenase activity
EO946_13960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EO946_13965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EO946_13970	COG0440	acetolactate synthase activity
EO946_13975	COG0028	Belongs to the TPP enzyme family
EO946_13985	COG0454	-acetyltransferase
EO946_13995	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
EO946_14005	COG0622	Phosphoesterase
EO946_14010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EO946_14015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EO946_14020	COG5401	PFAM Sporulation and spore germination
EO946_14025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EO946_14030	COG1846	Transcriptional regulator
EO946_14035	COG2197	response regulator
EO946_14040	COG0824	Thioesterase
EO946_14045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EO946_14050	COG1053	succinate dehydrogenase
EO946_14055	COG2009	succinate dehydrogenase
EO946_14060	COG1719	4-vinyl reductase, 4VR
EO946_14065	COG0527	aspartate kinase activity
EO946_14075	COG0322	excinuclease ABC activity
EO946_14080	COG3118	belongs to the thioredoxin family
EO946_14090	COG3534	alpha-L-arabinofuranosidase
EO946_14095	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EO946_14100	COG2086	electron transfer activity
EO946_14105	COG1024	Enoyl-CoA hydratase
EO946_14110	COG1309	transcriptional regulator
EO946_14115	COG0318	PFAM AMP-dependent synthetase and ligase
EO946_14120	COG3766	membrane
EO946_14125	COG1193	negative regulation of DNA recombination
EO946_14130	COG1796	DNA polymerase
EO946_14130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EO946_14135	COG1286	toxin biosynthetic process
EO946_14140	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EO946_14145	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EO946_14150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EO946_14150	COG0072	phenylalanine-tRNA ligase activity
EO946_14155	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EO946_14165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EO946_14175	COG0584	glycerophosphoryl diester phosphodiesterase
EO946_14180	COG3493	citrate carrier protein
EO946_14185	COG0277	FAD linked oxidase domain protein
EO946_14190	COG0247	lactate metabolic process
EO946_14195	COG0346	lactoylglutathione lyase activity
EO946_14205	COG1966	Carbon starvation protein
EO946_14220	COG1695	Transcriptional regulator
EO946_14225	COG3534	alpha-L-arabinofuranosidase
EO946_14230	COG0395	ABC-type sugar transport system, permease component
EO946_14235	COG1175	transmembrane transport
EO946_14240	COG1653	transport
EO946_14245	COG0371	Dehydrogenase
EO946_14250	COG0647	UMP catabolic process
EO946_14255	COG0235	Class ii aldolase
EO946_14260	COG1069	ribulokinase activity
EO946_14265	COG2160	L-arabinose isomerase activity
EO946_14270	COG3507	Belongs to the glycosyl hydrolase 43 family
EO946_14275	COG1363	Peptidase, m42
EO946_14285	COG3326	Membrane
EO946_14290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EO946_14295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EO946_14300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EO946_14315	COG1346	cytolysis
EO946_14320	COG1380	Effector of murein hydrolase LrgA
EO946_14325	COG3279	Response regulator of the LytR AlgR family
EO946_14330	COG3275	phosphorelay sensor kinase activity
EO946_14340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EO946_14350	COG0398	Pfam SNARE associated Golgi protein
EO946_14355	COG1484	DNA-dependent DNA replication
EO946_14360	COG3611	Membrane attachment protein
EO946_14365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EO946_14370	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EO946_14375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EO946_14380	COG1733	regulation of RNA biosynthetic process
EO946_14385	COG2814	Major facilitator Superfamily
EO946_14390	COG0656	L-ascorbic acid biosynthetic process
EO946_14395	COG0237	dephospho-CoA kinase activity
EO946_14400	COG1971	Probably functions as a manganese efflux pump
EO946_14405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EO946_14410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EO946_14410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EO946_14415	COG5002	protein histidine kinase activity
EO946_14420	COG0745	RESPONSE REGULATOR receiver
EO946_14425	COG0039	L-malate dehydrogenase activity
EO946_14430	COG0538	isocitrate dehydrogenase activity
EO946_14435	COG0372	Belongs to the citrate synthase family
EO946_14440	COG2707	UPF0756 membrane protein
EO946_14445	COG0628	permease
EO946_14450	COG3030	protein affecting phage T7 exclusion by the F plasmid
EO946_14455	COG0469	pyruvate kinase activity
EO946_14460	COG0205	6-phosphofructokinase activity
EO946_14465	COG0825	malonyl-CoA metabolic process
EO946_14470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EO946_14475	COG0281	malic enzyme
EO946_14480	COG0587	DNA-directed DNA polymerase activity
EO946_14500	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EO946_14510	COG4109	DRTGG domain
EO946_14515	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EO946_14520	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_14530	COG0165	Argininosuccinate lyase
EO946_14535	COG0137	argininosuccinate synthase activity
EO946_14540	COG0521	Mo-molybdopterin cofactor biosynthetic process
EO946_14545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EO946_14550	COG0827	DNA restriction-modification system
EO946_14555	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EO946_14560	COG3874	Sporulation protein YtfJ
EO946_14570	COG1714	RDD family
EO946_14575	COG0616	signal peptide processing
EO946_14580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EO946_14585	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EO946_14590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EO946_14600	COG0301	tRNA thio-modification
EO946_14605	COG1104	cysteine desulfurase activity
EO946_14610	COG1114	Component of the transport system for branched-chain amino acids
EO946_14615	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EO946_14620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EO946_14625	COG1309	transcriptional regulator
EO946_14630	COG1956	GAF domain-containing protein
EO946_14635	COG2203	Gaf domain
EO946_14635	COG2199	diguanylate cyclase activity
EO946_14645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EO946_14650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EO946_14655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EO946_14660	COG0454	-acetyltransferase
EO946_14665	COG0517	IMP dehydrogenase activity
EO946_14670	COG0123	including yeast histone deacetylase and acetoin utilization protein
EO946_14675	COG1360	Flagellar Motor Protein
EO946_14680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EO946_14685	COG1609	Transcriptional regulator
EO946_14690	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EO946_14690	COG1605	Chorismate mutase
EO946_14695	COG3118	belongs to the thioredoxin family
EO946_14700	COG4980	gas vesicle protein
EO946_14705	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EO946_14710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EO946_14715	COG1674	ftsk spoiiie
EO946_14720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EO946_14725	COG4848	Belongs to the UPF0354 family
EO946_14730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_14745	COG1363	Peptidase, m42
EO946_14750	COG5584	Small secreted protein
EO946_14755	COG0281	malic enzyme
EO946_14760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EO946_14765	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EO946_14775	COG0510	thiamine kinase activity
EO946_14780	COG1523	belongs to the glycosyl hydrolase 13 family
EO946_14785	COG1597	lipid kinase activity
EO946_14795	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EO946_14800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EO946_14805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EO946_14810	COG2252	PERMEase
EO946_14815	COG4473	ABC transporter
EO946_14820	COG1131	(ABC) transporter
EO946_14825	COG1349	DNA-binding transcription factor activity
EO946_14830	COG1187	pseudouridine synthase activity
EO946_14835	COG2244	polysaccharide biosynthetic process
EO946_14840	COG2081	HI0933 family
EO946_14845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EO946_14855	COG5578	integral membrane protein
EO946_14860	COG0673	inositol 2-dehydrogenase activity
EO946_14865	COG1653	transport
EO946_14870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EO946_14875	COG4209	transmembrane transport
EO946_14880	COG2207	Transcriptional regulator
EO946_14885	COG1653	transport
EO946_14890	COG0395	ABC-type sugar transport system, permease component
EO946_14895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EO946_14900	COG2124	cytochrome p450
EO946_14905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EO946_14915	COG0156	8-amino-7-oxononanoate synthase activity
EO946_14920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EO946_14935	COG1073	alpha beta
EO946_14960	COG1486	melibiose metabolic process
EO946_14965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EO946_14970	COG0495	leucyl-tRNA aminoacylation
EO946_14980	COG2202	Pas domain
EO946_14980	COG1366	Belongs to the anti-sigma-factor antagonist family
EO946_14985	COG2814	Major facilitator Superfamily
EO946_14990	COG2433	Pfam Transposase IS66
EO946_14995	COG0577	efflux transmembrane transporter activity
EO946_15000	COG1136	(ABC) transporter
EO946_15005	COG2205	protein histidine kinase activity
EO946_15010	COG0745	RESPONSE REGULATOR receiver
EO946_15015	COG0577	efflux transmembrane transporter activity
EO946_15020	COG1136	(ABC) transporter
EO946_15035	COG1131	(ABC) transporter
EO946_15040	COG1725	Transcriptional regulator
EO946_15055	COG1242	4 iron, 4 sulfur cluster binding
EO946_15060	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EO946_15070	COG2267	carboxylic ester hydrolase activity
EO946_15075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EO946_15080	COG1113	amino acid transport
EO946_15085	COG0367	asparagine synthase
EO946_15090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EO946_15095	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EO946_15105	COG1506	peptidase
EO946_15110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EO946_15115	COG1116	anion transmembrane transporter activity
EO946_15120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EO946_15130	COG0494	nUDIX hydrolase
EO946_15135	COG4824	toxin secretion phage lysis holin
EO946_15145	COG0783	Belongs to the Dps family
EO946_15160	COG1854	S-ribosylhomocysteine lyase activity
EO946_15165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EO946_15170	COG0288	reversible hydration of carbon dioxide
EO946_15175	COG0254	rRNA binding
EO946_15180	COG1271	oxidase subunit
EO946_15185	COG1294	oxidase, subunit
EO946_15195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EO946_15200	COG1321	iron dependent repressor
EO946_15200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EO946_15205	COG1121	(ABC) transporter
EO946_15210	COG0803	Belongs to the bacterial solute-binding protein 9 family
EO946_15215	COG4948	Mandelate Racemase Muconate Lactonizing
EO946_15220	COG0318	PFAM AMP-dependent synthetase and ligase
EO946_15225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EO946_15230	COG0596	Alpha beta hydrolase
EO946_15235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EO946_15240	COG1169	isochorismate synthase
EO946_15245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EO946_15250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EO946_15255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EO946_15260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EO946_15265	COG0438	transferase activity, transferring glycosyl groups
EO946_15275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EO946_15280	COG0438	transferase activity, transferring glycosyl groups
EO946_15285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EO946_15290	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EO946_15295	COG0058	SHG alpha-glucan phosphorylase activity
EO946_15300	COG0297	glycogen (starch) synthase activity
EO946_15305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EO946_15310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EO946_15315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EO946_15440	COG3859	Proton-coupled thiamine transporter YuaJ
EO946_15445	COG1247	-acetyltransferase
EO946_15450	COG2268	Band 7 protein
EO946_15455	COG1585	Membrane protein implicated in regulation of membrane protease activity
EO946_15460	COG2318	DinB family
EO946_15470	COG1454	alcohol dehydrogenase
EO946_15480	COG1510	regulation of RNA biosynthetic process
EO946_15490	COG0569	domain protein
EO946_15495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EO946_15500	COG4682	membrane
EO946_15505	COG1705	Flagellar rod assembly protein muramidase FlgJ
EO946_15510	COG0477	Major facilitator Superfamily
EO946_15515	COG5553	Cysteine dioxygenase type I
EO946_15525	COG1968	undecaprenyl-diphosphatase activity
EO946_15530	COG0628	permease
EO946_15535	COG0673	inositol 2-dehydrogenase activity
EO946_15540	COG4806	L-rhamnose isomerase
EO946_15545	COG3254	rhamnose metabolic process
EO946_15550	COG1070	Carbohydrate kinase
EO946_15555	COG1349	DNA-binding transcription factor activity
EO946_15560	COG3347	Dehydrogenase
EO946_15560	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_15565	COG0840	transmembrane signaling receptor activity
EO946_15570	COG0840	transmembrane signaling receptor activity
EO946_15575	COG0840	transmembrane signaling receptor activity
EO946_15580	COG0840	transmembrane signaling receptor activity
EO946_15595	COG2070	2-Nitropropane dioxygenase
EO946_15600	COG0432	Pfam Uncharacterised protein family UPF0047
EO946_15605	COG0366	Alpha amylase catalytic
EO946_15615	COG1253	flavin adenine dinucleotide binding
EO946_15620	COG2738	Putative neutral zinc metallopeptidase
EO946_15635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EO946_15650	COG0166	Belongs to the GPI family
EO946_15655	COG1979	alcohol dehydrogenase
EO946_15660	COG1979	alcohol dehydrogenase
EO946_15665	COG2155	Conserved Protein
EO946_15670	COG1098	S1 RNA binding domain
EO946_15675	COG0436	Aminotransferase
EO946_15680	COG1522	sequence-specific DNA binding
EO946_15685	COG2267	carboxylic ester hydrolase activity
EO946_15695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EO946_15700	COG2205	protein histidine kinase activity
EO946_15710	COG5018	Exonuclease
EO946_15720	COG2814	Major facilitator Superfamily
EO946_15725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EO946_15730	COG3011	Protein conserved in bacteria
EO946_15740	COG3290	protein histidine kinase activity
EO946_15745	COG4565	transcriptional regulatory protein
EO946_15750	COG3493	citrate carrier protein
EO946_15760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EO946_15760	COG2111	Na H antiporter
EO946_15765	COG2111	Na H antiporter
EO946_15770	COG1006	Multisubunit Na H antiporter MnhC subunit
EO946_15775	COG0651	ATP synthesis coupled electron transport
EO946_15780	COG1863	multisubunit Na H antiporter MnhE subunit
EO946_15785	COG2212	antiporter activity
EO946_15790	COG1320	monovalent cation:proton antiporter activity
EO946_15795	COG2050	protein possibly involved in aromatic compounds catabolism
EO946_15800	COG2197	response regulator
EO946_15805	COG4585	Histidine kinase
EO946_15815	COG0142	geranyltranstransferase activity
EO946_15835	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EO946_15840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EO946_15845	COG1335	isochorismatase
EO946_15850	COG5506	Protein of unknown function (DUF1694)
EO946_15865	COG0628	permease
EO946_15880	COG1418	mRNA catabolic process
EO946_15885	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_15895	COG1511	domain protein
EO946_15900	COG1674	ftsk spoiiie
EO946_15900	COG0433	COG0433 Predicted ATPase
EO946_15905	COG4499	WXG100 protein secretion system (Wss), protein YukC
EO946_15910	COG5417	Belongs to the EsaB family
EO946_15915	COG4842	Belongs to the WXG100 family
EO946_15920	COG2508	Transcriptional regulator
EO946_15920	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EO946_15925	COG0686	Belongs to the AlaDH PNT family
EO946_15930	COG5634	Uncharacterized conserved protein (DUF2278)
EO946_15935	COG3251	PFAM MbtH domain protein
EO946_15940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_15945	COG3433	isochorismatase activity
EO946_15945	COG1535	isochorismatase
EO946_15950	COG1021	2,3-dihydroxybenzoate-AMP ligase
EO946_15955	COG1169	isochorismate synthase
EO946_15960	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_15965	COG2819	hydrolase of the alpha beta superfamily
EO946_15970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EO946_15975	COG1268	BioY protein
EO946_15980	COG2056	Na+-H+ antiporter family
EO946_15985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EO946_15990	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EO946_15995	COG3584	3D domain protein
EO946_16010	COG1252	NADH dehydrogenase
EO946_16015	COG0492	ferredoxin-NADP+ reductase activity
EO946_16025	COG0516	GMP reductase activity
EO946_16040	COG1131	(ABC) transporter
EO946_16065	COG0456	acetyltransferase
EO946_16075	COG0316	Belongs to the HesB IscA family
EO946_16080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EO946_16085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EO946_16090	COG4844	belongs to the
EO946_16095	COG1252	NADH dehydrogenase
EO946_16100	COG4837	Protein of unknown function (DUF1462)
EO946_16105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EO946_16110	COG4946	Tricorn protease homolog
EO946_16110	COG1506	peptidase
EO946_16110	COG0823	Involved in the tonB-independent uptake of proteins
EO946_16115	COG0083	homoserine kinase activity
EO946_16120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EO946_16125	COG0460	homoserine dehydrogenase
EO946_16130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EO946_16135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EO946_16140	COG0647	UMP catabolic process
EO946_16145	COG2445	Protein of unknown function DUF86
EO946_16150	COG4470	Protein conserved in bacteria
EO946_16160	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EO946_16165	COG0739	heme binding
EO946_16175	COG3377	Domain of unknown function (DUF1805)
EO946_16180	COG0737	Belongs to the 5'-nucleotidase family
EO946_16185	COG0730	response to heat
EO946_16190	COG1801	Protein of unknown function DUF72
EO946_16200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EO946_16205	COG2508	Transcriptional regulator
EO946_16210	COG2233	PERMEase
EO946_16215	COG2233	PERMEase
EO946_16220	COG3195	allantoin biosynthetic process
EO946_16220	COG3648	Uricase
EO946_16225	COG2351	hydroxyisourate hydrolase activity
EO946_16240	COG2080	2 iron, 2 sulfur cluster binding
EO946_16245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EO946_16250	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EO946_16255	COG2068	MobA-Related Protein
EO946_16260	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EO946_16265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EO946_16270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EO946_16280	COG2356	endonuclease I
EO946_16285	COG3842	ATPase activity
EO946_16290	COG2188	Transcriptional regulator
EO946_16295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EO946_16300	COG0395	ABC-type sugar transport system, permease component
EO946_16305	COG1175	transmembrane transport
EO946_16310	COG1653	transport
EO946_16315	COG2222	sugar isomerase
EO946_16320	COG0322	excinuclease ABC activity
EO946_16325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EO946_16340	COG0346	lactoylglutathione lyase activity
EO946_16345	COG0640	Transcriptional regulator
EO946_16350	COG0719	Fe-S assembly protein
EO946_16355	COG0822	iron-sulfur transferase activity
EO946_16360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EO946_16365	COG0719	Fe-S assembly protein
EO946_16370	COG0396	ATPase activity
EO946_16385	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EO946_16390	COG1464	Belongs to the NlpA lipoprotein family
EO946_16395	COG2011	ABC-type metal ion transport system permease component
EO946_16400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EO946_16410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EO946_16415	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EO946_16425	COG0509	glycine decarboxylation via glycine cleavage system
EO946_16430	COG1393	Belongs to the ArsC family
EO946_16435	COG1960	acyl-CoA dehydrogenase activity
EO946_16440	COG0183	Belongs to the thiolase family
EO946_16445	COG1250	3-hydroxyacyl-CoA dehydrogenase
EO946_16445	COG1024	Enoyl-CoA hydratase
EO946_16455	COG0506	proline dehydrogenase activity
EO946_16465	COG5577	PFAM Coat F domain
EO946_16470	COG1846	Transcriptional regulator
EO946_16475	COG0477	Major facilitator Superfamily
EO946_16480	COG1942	4-Oxalocrotonate Tautomerase
EO946_16485	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_16490	COG0583	DNA-binding transcription factor activity
EO946_16500	COG1120	ATPase activity
EO946_16515	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_16520	COG0783	Belongs to the Dps family
EO946_16525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EO946_16530	COG0745	RESPONSE REGULATOR receiver
EO946_16535	COG2770	Histidine kinase
EO946_16535	COG2205	protein histidine kinase activity
EO946_16545	COG1309	transcriptional regulator
EO946_16550	COG0114	fumarate hydratase activity
EO946_16560	COG0697	spore germination
EO946_16565	COG0814	amino acid
EO946_16575	COG2197	response regulator
EO946_16580	COG4585	Histidine kinase
EO946_16585	COG4758	membrane
EO946_16590	COG3595	metallopeptidase activity
EO946_16595	COG1842	Phage shock protein A
EO946_16600	COG4758	membrane
EO946_16605	COG2814	Major facilitator Superfamily
EO946_16610	COG2096	Adenosyltransferase
EO946_16615	COG1120	ATPase activity
EO946_16620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_16625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EO946_16630	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_16635	COG3386	PFAM SMP-30 Gluconolaconase
EO946_16640	COG2205	protein histidine kinase activity
EO946_16645	COG0745	RESPONSE REGULATOR receiver
EO946_16655	COG1191	sigma factor activity
EO946_16665	COG2140	Oxalate decarboxylase
EO946_16675	COG0577	efflux transmembrane transporter activity
EO946_16680	COG1136	(ABC) transporter
EO946_16685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EO946_16690	COG1120	ATPase activity
EO946_16695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_16700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EO946_16705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EO946_16715	COG0531	amino acid
EO946_16730	COG1988	membrane-bound metal-dependent
EO946_16735	COG1368	sulfuric ester hydrolase activity
EO946_16740	COG1910	domain protein
EO946_16745	COG0725	ABC transporter, periplasmic molybdate-binding protein
EO946_16750	COG4149	molybdate abc transporter
EO946_16755	COG0656	L-ascorbic acid biosynthetic process
EO946_16765	COG0025	NhaP-type Na H and K H
EO946_16770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EO946_16775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EO946_16780	COG3973	AAA domain
EO946_16785	COG2860	membrane
EO946_16790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EO946_16795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EO946_16800	COG2217	Heavy metal translocating P-type atpase
EO946_16805	COG2217	Heavy metal translocating P-type atpase
EO946_16810	COG2608	mercury ion transmembrane transporter activity
EO946_16815	COG1937	Protein conserved in bacteria
EO946_16820	COG0673	inositol 2-dehydrogenase activity
EO946_16825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EO946_16830	COG1289	transmembrane transporter activity
EO946_16835	COG1802	Transcriptional regulator
EO946_16840	COG0697	spore germination
EO946_16845	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_16870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EO946_16875	COG0557	exoribonuclease II activity
EO946_16880	COG1647	Serine aminopeptidase, S33
EO946_16885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EO946_16890	COG0596	Alpha beta hydrolase
EO946_16895	COG1476	TRANSCRIPTIONal
EO946_16900	COG1396	sequence-specific DNA binding
EO946_16905	COG1396	sequence-specific DNA binding
EO946_16910	COG1733	regulation of RNA biosynthetic process
EO946_16965	COG1174	glycine betaine transport
EO946_16970	COG1732	Glycine betaine
EO946_16975	COG1174	glycine betaine transport
EO946_16980	COG0517	IMP dehydrogenase activity
EO946_16980	COG1125	glycine betaine transport
EO946_16985	COG1510	regulation of RNA biosynthetic process
EO946_16995	COG1174	glycine betaine transport
EO946_17000	COG1732	Glycine betaine
EO946_17005	COG1174	glycine betaine transport
EO946_17010	COG1125	glycine betaine transport
EO946_17010	COG0517	IMP dehydrogenase activity
EO946_17015	COG1510	regulation of RNA biosynthetic process
EO946_17020	COG2095	MarC family integral membrane protein
EO946_17030	COG3064	Membrane
EO946_17035	COG4640	response to antibiotic
EO946_17040	COG0456	acetyltransferase
EO946_17050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EO946_17055	COG0149	triose-phosphate isomerase activity
EO946_17060	COG0126	phosphoglycerate kinase activity
EO946_17070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EO946_17075	COG2390	Transcriptional regulator
EO946_17080	COG2814	Major facilitator Superfamily
EO946_17085	COG1609	Transcriptional regulator
EO946_17090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EO946_17095	COG0697	spore germination
EO946_17100	COG1113	amino acid transport
EO946_17105	COG3858	chitin binding
EO946_17110	COG1556	Lactate utilization protein
EO946_17115	COG1139	Iron-sulfur cluster binding protein
EO946_17120	COG0247	lactate metabolic process
EO946_17135	COG2197	response regulator
EO946_17140	COG4585	Histidine kinase
EO946_17145	COG0842	Transport permease protein
EO946_17150	COG1131	(ABC) transporter
EO946_17155	COG0596	Alpha beta hydrolase
EO946_17160	COG2208	phosphoserine phosphatase activity
EO946_17170	COG1874	Beta-galactosidase
EO946_17175	COG3833	ABC-type maltose transport systems, permease component
EO946_17180	COG1175	transmembrane transport
EO946_17185	COG2182	Extracellular solute-binding protein
EO946_17190	COG1609	Transcriptional regulator
EO946_17195	COG2186	Transcriptional regulator
EO946_17200	COG1620	l-lactate permease
EO946_17205	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EO946_17215	COG5039	Polysaccharide pyruvyl transferase
EO946_17220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EO946_17225	COG0110	maltose O-acetyltransferase activity
EO946_17230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EO946_17235	COG2244	polysaccharide biosynthetic process
EO946_17240	COG1216	Glycosyl transferase, family 2
EO946_17245	COG5039	Polysaccharide pyruvyl transferase
EO946_17250	COG1216	Glycosyl transferase, family 2
EO946_17260	COG0438	transferase activity, transferring glycosyl groups
EO946_17265	COG1215	transferase activity, transferring glycosyl groups
EO946_17270	COG0438	transferase activity, transferring glycosyl groups
EO946_17275	COG1086	Polysaccharide biosynthesis protein
EO946_17280	COG0489	protein tyrosine kinase activity
EO946_17285	COG3944	biosynthesis protein
EO946_17290	COG1396	sequence-specific DNA binding
EO946_17295	COG2272	Belongs to the type-B carboxylesterase lipase family
EO946_17305	COG3479	Phenolic acid decarboxylase
EO946_17315	COG1794	racemase activity, acting on amino acids and derivatives
EO946_17320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EO946_17325	COG1621	beta-fructofuranosidase activity
EO946_17330	COG1621	beta-fructofuranosidase activity
EO946_17335	COG0531	amino acid
EO946_17340	COG1309	transcriptional regulator
EO946_17345	COG2076	Multidrug Resistance protein
EO946_17350	COG2076	Multidrug Resistance protein
EO946_17370	COG1611	Belongs to the LOG family
EO946_17375	COG1694	Mazg nucleotide pyrophosphohydrolase
EO946_17380	COG0659	secondary active sulfate transmembrane transporter activity
EO946_17385	COG0288	reversible hydration of carbon dioxide
EO946_17390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EO946_17395	COG0577	efflux transmembrane transporter activity
EO946_17400	COG1136	(ABC) transporter
EO946_17405	COG5002	protein histidine kinase activity
EO946_17410	COG0745	RESPONSE REGULATOR receiver
EO946_17420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EO946_17425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EO946_17430	COG1481	regulation of sporulation
EO946_17435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EO946_17440	COG1660	Displays ATPase and GTPase activities
EO946_17445	COG1051	belongs to the nudix hydrolase family
EO946_17450	COG0492	ferredoxin-NADP+ reductase activity
EO946_17455	COG3883	PFAM NLP P60 protein
EO946_17455	COG0791	NLP P60 protein
EO946_17460	COG0457	Tetratricopeptide repeat
EO946_17465	COG1132	(ABC) transporter
EO946_17485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EO946_17485	COG0140	phosphoribosyl-ATP diphosphatase activity
EO946_17490	COG0107	imidazoleglycerol-phosphate synthase activity
EO946_17495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EO946_17500	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EO946_17505	COG0131	Imidazoleglycerol-phosphate dehydratase
EO946_17510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EO946_17515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EO946_17520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EO946_17525	COG4990	cell redox homeostasis
EO946_17530	COG5297	Belongs to the glycosyl hydrolase family 6
EO946_17535	COG0110	maltose O-acetyltransferase activity
EO946_17540	COG0546	phosphoglycolate phosphatase activity
EO946_17545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EO946_17550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EO946_17555	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EO946_17560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EO946_17565	COG0363	glucosamine-6-phosphate deaminase activity
EO946_17575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EO946_17580	COG1846	Transcriptional regulator
EO946_17585	COG2124	cytochrome p450
EO946_17595	COG1846	Transcriptional regulator
EO946_17600	COG2814	Major facilitator Superfamily
EO946_17605	COG1950	PFAM Membrane protein of
EO946_17610	COG1983	PspC domain protein
EO946_17615	COG3595	metallopeptidase activity
EO946_17630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EO946_17640	COG4897	Protein conserved in bacteria
EO946_17650	COG3848	Pyruvate phosphate dikinase
EO946_17650	COG0574	Belongs to the PEP-utilizing enzyme family
EO946_17655	COG1309	transcriptional regulator
EO946_17660	COG2814	Major facilitator Superfamily
EO946_17665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EO946_17675	COG0793	Belongs to the peptidase S41A family
EO946_17675	COG3409	Peptidoglycan-binding domain 1 protein
EO946_17680	COG2177	Part of the ABC transporter FtsEX involved in
EO946_17685	COG2884	Cell division ATP-binding protein ftsE
EO946_17690	COG2010	Cytochrome c
EO946_17695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EO946_17705	COG0653	protein targeting
EO946_17710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EO946_17725	COG1516	flagellar protein fliS
EO946_17730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EO946_17735	COG1334	flagellar protein FlaG
EO946_17740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EO946_17745	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EO946_17750	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EO946_17760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EO946_17765	COG4786	Flagellar basal body rod
EO946_17765	COG1256	bacterial-type flagellum assembly
EO946_17770	COG3418	PFAM FlgN family protein
EO946_17775	COG2747	anti-sigma28 factor FlgM
EO946_17785	COG1040	competence protein
EO946_17795	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EO946_17800	COG1307	EDD domain protein, DegV family
EO946_17805	COG2197	response regulator
EO946_17810	COG4585	Histidine kinase
EO946_17815	COG1739	Uncharacterized protein family UPF0029
EO946_17820	COG1316	TRANSCRIPTIONal
EO946_17825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EO946_17830	COG0438	transferase activity, transferring glycosyl groups
EO946_17835	COG1215	transferase activity, transferring glycosyl groups
EO946_17840	COG3206	protein involved in exopolysaccharide biosynthesis
EO946_17845	COG3307	-O-antigen
EO946_17850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EO946_17855	COG0297	glycogen (starch) synthase activity
EO946_17855	COG0438	transferase activity, transferring glycosyl groups
EO946_17860	COG2244	polysaccharide biosynthetic process
EO946_17875	COG0860	N-Acetylmuramoyl-L-alanine amidase
EO946_17875	COG2247	cell wall binding repeat
EO946_17880	COG2385	sporulation resulting in formation of a cellular spore
EO946_17880	COG2247	cell wall binding repeat
EO946_17890	COG1316	TRANSCRIPTIONal
EO946_17895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EO946_17915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EO946_17920	COG1134	teichoic acid transport
EO946_17925	COG1682	transport, permease protein
EO946_17940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EO946_17940	COG1215	transferase activity, transferring glycosyl groups
EO946_17945	COG0463	Glycosyl transferase, family 2
EO946_17990	COG4193	domain, Protein
EO946_17995	COG1482	cell wall glycoprotein biosynthetic process
EO946_18000	COG0697	spore germination
EO946_18005	COG0814	amino acid
EO946_18015	COG2814	Major facilitator Superfamily
EO946_18020	COG1316	TRANSCRIPTIONal
EO946_18025	COG0561	phosphatase activity
EO946_18030	COG0791	NLP P60 protein
EO946_18040	COG2843	Capsule synthesis protein
EO946_18050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EO946_18055	COG1609	Transcriptional regulator
EO946_18060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EO946_18065	COG1869	D-ribose catabolic process
EO946_18070	COG1129	ABC transporter
EO946_18075	COG1172	Belongs to the binding-protein-dependent transport system permease family
EO946_18080	COG1879	ABC-type sugar transport system periplasmic component
EO946_18085	COG3103	Sh3 type 3 domain protein
EO946_18095	COG2249	NAD(P)H dehydrogenase (quinone) activity
EO946_18100	COG3527	Alpha-acetolactate decarboxylase
EO946_18105	COG0028	Belongs to the TPP enzyme family
EO946_18110	COG0583	DNA-binding transcription factor activity
EO946_18115	COG5337	Spore coat protein CotH
EO946_18125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EO946_18135	COG0405	Gamma-glutamyltransferase
EO946_18140	COG1522	sequence-specific DNA binding
EO946_18145	COG2059	Chromate
EO946_18150	COG2059	Chromate
EO946_18160	COG0655	NAD(P)H dehydrogenase (quinone) activity
EO946_18165	COG0583	DNA-binding transcription factor activity
EO946_18175	COG2207	Transcriptional regulator
EO946_18175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EO946_18210	COG5444	nuclease activity
EO946_18225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EO946_18230	COG4464	protein tyrosine phosphatase activity
EO946_18235	COG0489	protein tyrosine kinase activity
EO946_18240	COG3944	biosynthesis protein
EO946_18250	COG4715	Zinc finger, swim domain protein
EO946_18255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EO946_18260	COG0561	phosphatase activity
EO946_18265	COG1349	DNA-binding transcription factor activity
EO946_18270	COG0629	single-stranded DNA binding
EO946_18285	COG3764	Sortase (surface protein transpeptidase)
EO946_18295	COG3279	Response regulator of the LytR AlgR family
EO946_18300	COG2972	Histidine kinase
EO946_18300	COG0745	RESPONSE REGULATOR receiver
EO946_18305	COG1970	mechanosensitive ion channel activity
EO946_18310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EO946_18315	COG0457	Tetratricopeptide repeat
EO946_18320	COG4786	Flagellar basal body rod
EO946_18325	COG4786	Flagellar basal body rod
EO946_18330	COG1077	Cell shape determining protein MreB Mrl
EO946_18335	COG1609	Transcriptional regulator
EO946_18345	COG1846	Transcriptional regulator
EO946_18350	COG2814	Major facilitator Superfamily
EO946_18355	COG3420	alginic acid biosynthetic process
EO946_18360	COG1953	Uracil, thiamine, allantoin
EO946_18365	COG0477	Major facilitator Superfamily
EO946_18370	COG1335	isochorismatase
EO946_18380	COG0004	ammonium transporteR
EO946_18385	COG0347	Belongs to the P(II) protein family
EO946_18390	COG0671	phosphoesterase, PA-phosphatase related
EO946_18400	COG0739	heme binding
EO946_18405	COG1247	-acetyltransferase
EO946_18415	COG2089	acid synthase
EO946_18425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EO946_18430	COG0789	Transcriptional regulator
EO946_18440	COG2910	NAD(P)H-binding
EO946_18445	COG1959	2 iron, 2 sulfur cluster binding
EO946_18450	COG0804	urea catabolic process
EO946_18455	COG0832	Belongs to the urease beta subunit family
EO946_18460	COG0831	urea catabolic process
EO946_18480	COG0559	Belongs to the binding-protein-dependent transport system permease family
EO946_18490	COG3237	CsbD-like
EO946_18495	COG1994	Peptidase M50
EO946_18500	COG0457	Tetratricopeptide repeat
EO946_18505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EO946_18510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EO946_18520	COG2304	oxidoreductase activity
EO946_18525	COG2304	oxidoreductase activity
EO946_18530	COG2385	sporulation resulting in formation of a cellular spore
EO946_18535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EO946_18545	COG4836	Membrane
EO946_18565	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EO946_18570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EO946_18575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EO946_18580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EO946_18585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EO946_18590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EO946_18595	COG0356	it plays a direct role in the translocation of protons across the membrane
EO946_18605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EO946_18610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EO946_18615	COG4475	Protein of unknown function (DUF436)
EO946_18620	COG0698	ribose 5-phosphate isomerase
EO946_18625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EO946_18630	COG1971	Probably functions as a manganese efflux pump
EO946_18635	COG0009	L-threonylcarbamoyladenylate synthase
EO946_18640	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EO946_18660	COG2890	protein-(glutamine-N5) methyltransferase activity
EO946_18665	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EO946_18670	COG0346	lactoylglutathione lyase activity
EO946_18675	COG0789	Transcriptional regulator
EO946_18680	COG0679	Auxin Efflux Carrier
EO946_18685	COG0281	malic enzyme
EO946_18690	COG1435	thymidine kinase activity
EO946_18695	COG0254	rRNA binding
EO946_18700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EO946_18710	COG1494	fructose-1,6-bisphosphatase
EO946_18715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EO946_18720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EO946_18725	COG0191	fructose-bisphosphate aldolase activity
EO946_18730	COG2204	response regulator
EO946_18735	COG4821	SIS domain
EO946_18740	COG0504	CTP synthase activity
EO946_18745	COG3343	RNA polymerase activity
EO946_18750	COG1960	acyl-CoA dehydrogenase activity
EO946_18755	COG2181	nitrate reductase activity
EO946_18755	COG0247	lactate metabolic process
EO946_18760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EO946_18765	COG4294	response to UV
EO946_18775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EO946_18780	COG1132	(ABC) transporter
EO946_18785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EO946_18795	COG2181	nitrate reductase activity
EO946_18800	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EO946_18805	COG1140	nitrate reductase beta subunit
EO946_18810	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EO946_18815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EO946_18825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EO946_18830	COG2223	nitrite transmembrane transporter activity
EO946_18835	COG0018	arginyl-trna synthetase
EO946_18840	COG4506	Protein conserved in bacteria
EO946_18850	COG0535	radical SAM domain protein
EO946_18860	COG1131	(ABC) transporter
EO946_18885	COG3391	amine dehydrogenase activity
EO946_18895	COG0457	Tetratricopeptide repeat
EO946_18905	COG0010	Belongs to the arginase family
EO946_18910	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EO946_18915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EO946_18930	COG1994	Peptidase M50
EO946_18935	COG1942	4-Oxalocrotonate Tautomerase
EO946_18940	COG1846	Transcriptional regulator
EO946_18945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EO946_18955	COG3465	dGTPase activity
EO946_18960	COG1078	dGTPase activity
EO946_18965	COG4844	belongs to the
EO946_18975	COG0697	spore germination
EO946_18980	COG0095	Lipoate-protein ligase
EO946_18985	COG0583	DNA-binding transcription factor activity
EO946_18990	COG0280	phosphate acetyltransferase
EO946_19000	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_19005	COG0436	Aminotransferase
EO946_19010	COG2814	Major facilitator Superfamily
EO946_19015	COG0151	Belongs to the GarS family
EO946_19020	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_19025	COG1917	Cupin 2, conserved barrel domain protein
EO946_19030	COG0077	Prephenate dehydratase
EO946_19035	COG2814	Major facilitator Superfamily
EO946_19040	COG0833	amino acid
EO946_19045	COG4187	Peptidase family M20/M25/M40
EO946_19050	COG1012	belongs to the aldehyde dehydrogenase family
EO946_19055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EO946_19065	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EO946_19070	COG1091	dTDP-4-dehydrorhamnose reductase activity
EO946_19075	COG1088	dTDP-glucose 4,6-dehydratase activity
EO946_19080	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EO946_19085	COG3980	spore coat polysaccharide biosynthesis protein
EO946_19090	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EO946_19095	COG2089	acid synthase
EO946_19100	COG0456	acetyltransferase
EO946_19105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EO946_19110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EO946_19115	COG0463	Glycosyl transferase, family 2
EO946_19130	COG2363	Small membrane protein
EO946_19135	COG2233	PERMEase
EO946_19145	COG1012	belongs to the aldehyde dehydrogenase family
EO946_19150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EO946_19155	COG1216	Glycosyl transferase, family 2
EO946_19170	COG1695	Transcriptional regulator
EO946_19175	COG0351	phosphomethylpyrimidine kinase
EO946_19185	COG1621	beta-fructofuranosidase activity
EO946_19190	COG1263	PTS System
EO946_19190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_19195	COG2116	formate transmembrane transporter activity
EO946_19200	COG3711	transcriptional antiterminator
EO946_19210	COG1404	Belongs to the peptidase S8 family
EO946_19215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EO946_19220	COG0778	Nitroreductase
EO946_19225	COG0772	Belongs to the SEDS family
EO946_19260	COG2261	transglycosylase associated protein
EO946_19265	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EO946_19270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EO946_19275	COG2246	polysaccharide biosynthetic process
EO946_19280	COG1309	transcriptional regulator
EO946_19290	COG3162	membrane
EO946_19295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EO946_19300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EO946_19305	COG2837	iron assimilation
EO946_19310	COG2822	iron ion transport
EO946_19315	COG0352	thiamine-phosphate diphosphorylase activity
EO946_19320	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EO946_19325	COG0583	DNA-binding transcription factor activity
EO946_19330	COG1380	Effector of murein hydrolase LrgA
EO946_19335	COG1346	cytolysis
EO946_19340	COG1131	(ABC) transporter
EO946_19365	COG1346	cytolysis
EO946_19370	COG2814	Major facilitator Superfamily
EO946_19375	COG4895	conserved protein (DUF2196)
EO946_19380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EO946_19385	COG0346	lactoylglutathione lyase activity
EO946_19395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EO946_19405	COG1404	Belongs to the peptidase S8 family
EO946_19415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_19415	COG1263	PTS System
EO946_19420	COG3711	transcriptional antiterminator
EO946_19425	COG1442	glycosyl transferase family 8
EO946_19430	COG5522	Integral membrane protein (intg_mem_TP0381)
EO946_19435	COG1846	Transcriptional regulator
EO946_19440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EO946_19445	COG2234	aminopeptidase activity
EO946_19450	COG2357	RelA SpoT domain protein
EO946_19460	COG1575	Belongs to the MenA family. Type 1 subfamily
EO946_19470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EO946_19475	COG1696	Membrane protein involved in D-alanine export
EO946_19480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EO946_19485	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EO946_19490	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EO946_19495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EO946_19500	COG1486	melibiose metabolic process
EO946_19505	COG1447	Phosphotransferase system cellobiose-specific component IIA
EO946_19510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EO946_19515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EO946_19520	COG3711	transcriptional antiterminator
EO946_19520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EO946_19530	COG2094	Belongs to the DNA glycosylase MPG family
EO946_19535	COG0753	catalase activity
EO946_19540	COG2814	Major facilitator Superfamily
EO946_19545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EO946_19550	COG1131	(ABC) transporter
EO946_19570	COG1595	DNA-templated transcription, initiation
EO946_19575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EO946_19580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EO946_19585	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EO946_19590	COG4988	ABC transporter
EO946_19595	COG1294	oxidase, subunit
EO946_19600	COG1271	oxidase subunit
EO946_19605	COG3493	citrate carrier protein
EO946_19620	COG0726	polysaccharide deacetylase
EO946_19635	COG3842	ATPase activity
EO946_19640	COG2508	Transcriptional regulator
EO946_19645	COG1012	belongs to the aldehyde dehydrogenase family
EO946_19650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EO946_19660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EO946_19670	COG2195	Cleaves the N-terminal amino acid of tripeptides
EO946_19680	COG4894	glucomannan catabolic process
EO946_19685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EO946_19690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EO946_19695	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_19700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EO946_19705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EO946_19710	COG2610	gluconate transmembrane transporter activity
EO946_19715	COG0500	methyltransferase
EO946_19720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EO946_19735	COG0753	catalase activity
EO946_19735	COG0693	protein deglycase activity
EO946_19740	COG2851	Citrate transporter
EO946_19745	COG2323	membrane
EO946_19755	COG2723	6-phospho-beta-galactosidase activity
EO946_19760	COG2190	(PTS) system
EO946_19760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_19760	COG1263	PTS System
EO946_19765	COG3711	transcriptional antiterminator
EO946_19775	COG2270	Major facilitator Superfamily
EO946_19780	COG0513	Belongs to the DEAD box helicase family
EO946_19785	COG2755	lipolytic protein G-D-S-L family
EO946_19785	COG3401	FG-GAP repeat protein
EO946_19900	COG0697	spore germination
EO946_19910	COG0861	Integral membrane protein TerC family
EO946_19915	COG0589	response to stress
EO946_19920	COG2723	6-phospho-beta-galactosidase activity
EO946_19925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EO946_19925	COG2190	(PTS) system
EO946_19925	COG1263	PTS System
EO946_19960	COG5444	nuclease activity
EO946_19975	COG3507	Belongs to the glycosyl hydrolase 43 family
EO946_19980	COG0673	inositol 2-dehydrogenase activity
EO946_19990	COG2986	histidine ammonia-lyase
EO946_19995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EO946_20000	COG1228	amidohydrolase
EO946_20005	COG0010	Belongs to the arginase family
EO946_20010	COG0833	amino acid
EO946_20015	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EO946_20020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EO946_20025	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EO946_20030	COG2390	Transcriptional regulator
EO946_20040	COG3192	ethanolamine utilization protein
EO946_20045	COG2079	MmgE PrpD family protein
EO946_20055	COG1126	abc transporter atp-binding protein
EO946_20060	COG0765	amino acid transport
EO946_20065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EO946_20080	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EO946_20085	COG0561	phosphatase activity
EO946_20115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EO946_20120	COG5294	Protein conserved in bacteria
EO946_20125	COG0577	efflux transmembrane transporter activity
EO946_20130	COG1136	(ABC) transporter
EO946_20135	COG2205	protein histidine kinase activity
EO946_20140	COG0745	RESPONSE REGULATOR receiver
EO946_20145	COG0191	fructose-bisphosphate aldolase activity
EO946_20150	COG1082	Xylose isomerase domain protein TIM barrel
EO946_20155	COG1082	Xylose isomerase domain protein TIM barrel
EO946_20160	COG0673	inositol 2-dehydrogenase activity
EO946_20165	COG2814	Major facilitator Superfamily
EO946_20170	COG1082	Xylose isomerase domain protein TIM barrel
EO946_20175	COG3962	Belongs to the TPP enzyme family
EO946_20180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EO946_20190	COG1012	belongs to the aldehyde dehydrogenase family
EO946_20195	COG1349	DNA-binding transcription factor activity
EO946_20200	COG0667	Aldo Keto reductase
EO946_20215	COG2814	Major facilitator Superfamily
EO946_20220	COG0326	Molecular chaperone. Has ATPase activity
EO946_20230	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_20240	COG1309	transcriptional regulator
EO946_20245	COG1012	belongs to the aldehyde dehydrogenase family
EO946_20260	COG1714	RDD family
EO946_20265	COG2311	Membrane
EO946_20270	COG1917	Cupin 2, conserved barrel domain protein
EO946_20275	COG1309	transcriptional regulator
EO946_20280	COG1028	Short-chain dehydrogenase reductase Sdr
EO946_20285	COG1846	Transcriptional regulator
EO946_20290	COG1380	Effector of murein hydrolase LrgA
EO946_20295	COG1346	cytolysis
EO946_20305	COG5039	Polysaccharide pyruvyl transferase
EO946_20310	COG1929	Belongs to the glycerate kinase type-1 family
EO946_20315	COG1802	Transcriptional regulator
EO946_20320	COG1070	Carbohydrate kinase
EO946_20325	COG2610	gluconate transmembrane transporter activity
EO946_20330	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EO946_20335	COG0450	alkyl hydroperoxide reductase
EO946_20340	COG3634	alkyl hydroperoxide reductase activity
EO946_20350	COG2723	6-phospho-beta-galactosidase activity
EO946_20360	COG2188	Transcriptional regulator
EO946_20370	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EO946_20375	COG0270	DNA (cytosine-5-)-methyltransferase activity
EO946_20400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EO946_20425	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EO946_20430	COG0456	acetyltransferase
EO946_20435	COG0457	Tetratricopeptide repeat
EO946_20445	COG0010	Belongs to the arginase family
EO946_20450	COG0833	amino acid
EO946_20455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EO946_20460	COG3829	transcription factor binding
EO946_20470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EO946_20475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EO946_20480	COG4853	Protein conserved in bacteria
EO946_20485	COG4863	YycH protein
EO946_20490	COG5002	protein histidine kinase activity
EO946_20495	COG0745	RESPONSE REGULATOR receiver
EO946_20525	COG0346	lactoylglutathione lyase activity
EO946_20530	COG0305	Participates in initiation and elongation during chromosome replication
EO946_20545	COG3093	addiction module antidote protein HigA
EO946_20550	COG2807	transmembrane transport
EO946_20555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EO946_20560	COG0359	binds to the 23S rRNA
EO946_20565	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EO946_20570	COG4241	membrane
EO946_20580	COG5577	PFAM Coat F domain
EO946_20585	COG1733	regulation of RNA biosynthetic process
EO946_20590	COG1227	inorganic diphosphatase activity
EO946_20605	COG2271	Major facilitator Superfamily
EO946_20620	COG2814	Major facilitator Superfamily
EO946_20625	COG0583	DNA-binding transcription factor activity
EO946_20630	COG2153	protein acetylation
EO946_20640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EO946_20655	COG1846	Transcriptional regulator
EO946_20660	COG2153	protein acetylation
EO946_20665	COG2364	Membrane
EO946_20670	COG1331	Highly conserved protein containing a thioredoxin domain
EO946_20675	COG1266	CAAX protease self-immunity
EO946_20680	COG2814	Major facilitator Superfamily
EO946_20680	COG0477	Major facilitator Superfamily
EO946_20685	COG0110	maltose O-acetyltransferase activity
EO946_20690	COG0346	lactoylglutathione lyase activity
EO946_20695	COG1609	Transcriptional regulator
EO946_20700	COG0708	Exodeoxyribonuclease III
EO946_20705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EO946_20710	COG0629	single-stranded DNA binding
EO946_20715	COG0360	Binds together with S18 to 16S ribosomal RNA
EO946_20720	COG0012	GTP binding
EO946_20725	COG0243	molybdopterin cofactor binding
EO946_20730	COG4481	Protein conserved in bacteria
EO946_20735	COG3949	Membrane
EO946_20745	COG1475	DNA binding
EO946_20750	COG1192	Involved in chromosome partitioning
EO946_20760	COG1475	DNA binding
EO946_20765	COG0357	Ribosomal RNA small subunit methyltransferase G
EO946_20770	COG0445	tRNA wobble uridine modification
EO946_20775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EO946_20780	COG1847	R3H domain protein
EO946_20785	COG0706	membrane insertase activity
EO946_20790	COG0594	ribonuclease P activity
EO946_20795	COG0230	Belongs to the bacterial ribosomal protein bL34 family