locus-tag	class	description
SD85_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SD85_00010	COG0592	DNA-directed DNA polymerase activity
SD85_00015	COG2501	S4 domain
SD85_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SD85_00030	COG0187	DNA topoisomerase II activity
SD85_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SD85_00070	COG0517	IMP dehydrogenase activity
SD85_00070	COG0516	GMP reductase activity
SD85_00075	COG1686	Belongs to the peptidase S11 family
SD85_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SD85_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SD85_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SD85_00100	COG1428	Deoxynucleoside kinase
SD85_00105	COG1428	Deoxynucleoside kinase
SD85_00110	COG1388	LysM domain
SD85_00110	COG3858	chitin binding
SD85_00115	COG1335	isochorismatase
SD85_00120	COG0590	tRNA wobble adenosine to inosine editing
SD85_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SD85_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SD85_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SD85_00180	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
SD85_00185	COG3853	Toxic anion resistance protein (TelA)
SD85_00190	COG1982	Orn Lys Arg decarboxylase major
SD85_00195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SD85_00200	COG3870	Protein conserved in bacteria
SD85_00205	COG1728	Protein conserved in bacteria
SD85_00210	COG0470	DNA polymerase III
SD85_00215	COG1774	PSP1 C-terminal conserved region
SD85_00220	COG4467	Involved in initiation control of chromosome replication
SD85_00225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SD85_00230	COG2827	Endonuclease containing a URI domain
SD85_00235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SD85_00240	COG2002	toxin-antitoxin pair type II binding
SD85_00245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD85_00245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD85_00250	COG0084	hydrolase, TatD family'
SD85_00255	COG3584	3D domain protein
SD85_00255	COG3583	domain protein
SD85_00260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SD85_00265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SD85_00275	COG4466	Protein conserved in bacteria
SD85_00285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SD85_00290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SD85_00295	COG0251	oxidation-reduction process
SD85_00300	COG2088	sporulation resulting in formation of a cellular spore
SD85_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SD85_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SD85_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SD85_00325	COG0193	aminoacyl-tRNA hydrolase activity
SD85_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SD85_00340	COG2002	toxin-antitoxin pair type II binding
SD85_00345	COG2244	polysaccharide biosynthetic process
SD85_00350	COG3956	TIGRFAM MazG family protein
SD85_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SD85_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SD85_00375	COG1098	S1 RNA binding domain
SD85_00390	COG2208	phosphoserine phosphatase activity
SD85_00395	COG2304	oxidoreductase activity
SD85_00400	COG0515	serine threonine protein kinase
SD85_00405	COG0037	tRNA processing
SD85_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SD85_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SD85_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SD85_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SD85_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SD85_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SD85_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
SD85_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SD85_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SD85_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SD85_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SD85_00470	COG1396	sequence-specific DNA binding
SD85_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SD85_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SD85_00505	COG4463	regulation of RNA biosynthetic process
SD85_00510	COG3880	PFAM UvrB UvrC protein
SD85_00515	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SD85_00520	COG0542	response to heat
SD85_00525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SD85_00530	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SD85_00535	COG4956	integral membrane protein (PIN domain superfamily)
SD85_00540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SD85_00545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SD85_00550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SD85_00560	COG1045	serine acetyltransferase
SD85_00565	COG0215	cysteine-tRNA ligase activity
SD85_00570	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SD85_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SD85_00580	COG3688	RNA-binding protein containing a PIN domain
SD85_00585	COG1595	DNA-templated transcription, initiation
SD85_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SD85_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SD85_00600	COG0250	Participates in transcription elongation, termination and antitermination
SD85_00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SD85_00610	COG0081	regulation of translation
SD85_00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SD85_00620	COG0222	ribosome binding
SD85_00625	COG2813	Specifically methylates the guanine in position
SD85_00630	COG0085	RNA polymerase activity
SD85_00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SD85_00640	COG1358	cellular component organization or biogenesis
SD85_00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SD85_00650	COG0049	tRNA binding
SD85_00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SD85_00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SD85_00665	COG0596	Alpha beta hydrolase
SD85_00670	COG0051	transcription antitermination factor activity, RNA binding
SD85_00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SD85_00680	COG0088	Forms part of the polypeptide exit tunnel
SD85_00685	COG0089	rRNA binding
SD85_00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SD85_00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SD85_00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SD85_00705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SD85_00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SD85_00715	COG0255	Belongs to the universal ribosomal protein uL29 family
SD85_00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SD85_00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SD85_00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SD85_00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SD85_00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SD85_00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SD85_00765	COG1841	ribosomal large subunit assembly
SD85_00770	COG0200	Binds to the 23S rRNA
SD85_00775	COG0201	protein transport
SD85_00780	COG0563	adenylate kinase activity
SD85_00785	COG0024	Methionine aminopeptidase
SD85_00790	COG2163	COG2163 Ribosomal protein L14E L6E L27E
SD85_00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SD85_00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SD85_00810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SD85_00815	COG0202	RNA polymerase activity
SD85_00820	COG0203	ribosomal protein L17
SD85_00825	COG1122	ATPase activity
SD85_00830	COG1122	ATPase activity
SD85_00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SD85_00840	COG0101	tRNA pseudouridine synthase activity
SD85_00860	COG2226	methyltransferase
SD85_00870	COG0860	N-Acetylmuramoyl-L-alanine amidase
SD85_00875	COG0489	protein tyrosine kinase activity
SD85_00885	COG2194	sulfuric ester hydrolase activity
SD85_00890	COG0726	polysaccharide deacetylase
SD85_00960	COG0659	secondary active sulfate transmembrane transporter activity
SD85_00965	COG0385	Bile acid
SD85_00970	COG2819	hydrolase of the alpha beta superfamily
SD85_00975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_00980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_00985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD85_00990	COG2207	Transcriptional regulator
SD85_00990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD85_00995	COG3876	Protein conserved in bacteria
SD85_01000	COG1472	Belongs to the glycosyl hydrolase 3 family
SD85_01005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SD85_01010	COG1263	PTS System
SD85_01010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_01015	COG1737	Transcriptional regulator
SD85_01020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SD85_01025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD85_01030	COG1683	Conserved Protein
SD85_01060	COG1595	DNA-templated transcription, initiation
SD85_01065	COG5662	AntiSigma factor
SD85_01070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SD85_01075	COG4856	YbbR-like protein
SD85_01080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SD85_01090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SD85_01095	COG3002	Belongs to the UPF0753 family
SD85_01110	COG5609	conserved protein (DUF2294)
SD85_01115	COG0596	Alpha beta hydrolase
SD85_01120	COG0745	RESPONSE REGULATOR receiver
SD85_01125	COG0642	Histidine kinase
SD85_01135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SD85_01145	COG2211	Major facilitator Superfamily
SD85_01155	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SD85_01155	COG0028	Belongs to the TPP enzyme family
SD85_01205	COG0515	serine threonine protein kinase
SD85_01220	COG1113	amino acid transport
SD85_01235	COG2602	Beta-lactamase
SD85_01240	COG2124	cytochrome p450
SD85_01250	COG1283	sodium-dependent phosphate transmembrane transporter activity
SD85_01255	COG0584	glycerophosphoryl diester phosphodiesterase
SD85_01260	COG2271	Major facilitator Superfamily
SD85_01270	COG1846	Transcriptional regulator
SD85_01270	COG0456	acetyltransferase
SD85_01275	COG2271	Major facilitator Superfamily
SD85_01290	COG0697	spore germination
SD85_01295	COG2207	Transcriptional regulator
SD85_01295	COG1917	Cupin 2, conserved barrel domain protein
SD85_01300	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SD85_01305	COG3591	Belongs to the peptidase S1B family
SD85_01315	COG0596	Alpha beta hydrolase
SD85_01320	COG1183	phosphatidylcholine synthase activity
SD85_01325	COG0586	Pfam SNARE associated Golgi protein
SD85_01330	COG0688	phosphatidylethanolamine metabolic process
SD85_01340	COG2312	Erythromycin esterase
SD85_01350	COG1301	dicarboxylic acid transport
SD85_01360	COG0363	glucosamine-6-phosphate deaminase activity
SD85_01375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SD85_01380	COG0833	amino acid
SD85_01385	COG2040	homocysteine
SD85_01395	COG1115	amino acid carrier protein
SD85_01400	COG2066	Belongs to the glutaminase family
SD85_01405	COG4191	Histidine kinase
SD85_01410	COG0784	Response regulator, receiver
SD85_01415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SD85_01420	COG1012	belongs to the aldehyde dehydrogenase family
SD85_01425	COG2271	Major facilitator Superfamily
SD85_01430	COG4948	Mandelate Racemase Muconate Lactonizing
SD85_01435	COG2186	Transcriptional regulator
SD85_01440	COG2721	sulfolactate sulfo-lyase activity
SD85_01445	COG3173	Aminoglycoside phosphotransferase
SD85_01455	COG0745	RESPONSE REGULATOR receiver
SD85_01460	COG2205	protein histidine kinase activity
SD85_01465	COG1131	(ABC) transporter
SD85_01485	COG3773	Cell wall hydrolase
SD85_01490	COG2304	oxidoreductase activity
SD85_01500	COG3540	Alkaline phosphatase
SD85_01505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SD85_01510	COG0805	protein transport
SD85_01515	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SD85_01520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SD85_01525	COG0477	Major facilitator Superfamily
SD85_01530	COG1309	transcriptional regulator
SD85_01535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SD85_01540	COG1714	RDD family
SD85_01545	COG3012	SEC-C Motif Domain Protein
SD85_01545	COG1405	negative regulation of cell septum assembly
SD85_01550	COG3290	protein histidine kinase activity
SD85_01555	COG1668	transmembrane transport
SD85_01560	COG0667	Aldo Keto reductase
SD85_01570	COG1595	DNA-templated transcription, initiation
SD85_01585	COG2801	Transposase and inactivated derivatives
SD85_01590	COG1595	DNA-templated transcription, initiation
SD85_01595	COG1876	peptidase activity
SD85_01600	COG0457	Tetratricopeptide repeat
SD85_01605	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_01610	COG0366	Alpha amylase catalytic
SD85_01615	COG0803	Belongs to the bacterial solute-binding protein 9 family
SD85_01620	COG1121	(ABC) transporter
SD85_01625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SD85_01630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SD85_01635	COG2310	stress, protein
SD85_01640	COG2310	stress, protein
SD85_01645	COG2310	stress, protein
SD85_01650	COG0861	Integral membrane protein TerC family
SD85_01660	COG3853	Toxic anion resistance protein (TelA)
SD85_01665	COG0477	Major facilitator Superfamily
SD85_01670	COG0640	Transcriptional regulator
SD85_01675	COG4175	Glycine betaine
SD85_01675	COG0517	IMP dehydrogenase activity
SD85_01680	COG4176	ABC-type proline glycine betaine transport system permease component
SD85_01685	COG2113	Glycine betaine
SD85_01690	COG1473	amidohydrolase
SD85_01695	COG1288	antiporter activity
SD85_01710	COG0366	Alpha amylase catalytic
SD85_01715	COG0039	L-malate dehydrogenase activity
SD85_01720	COG1620	l-lactate permease
SD85_01725	COG2814	Major facilitator Superfamily
SD85_01730	COG1846	Transcriptional regulator
SD85_01735	COG1280	lysine exporter protein (LysE YggA)
SD85_01740	COG3403	YqcI/YcgG family
SD85_01745	COG1113	amino acid transport
SD85_01750	COG3665	Urea carboxylase-associated protein
SD85_01755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SD85_01760	COG1660	Displays ATPase and GTPase activities
SD85_01765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SD85_01770	COG2226	methyltransferase
SD85_01775	COG0583	DNA-binding transcription factor activity
SD85_01780	COG3458	cephalosporin-C deacetylase activity
SD85_01785	COG3541	Predicted nucleotidyltransferase
SD85_01790	COG0506	proline dehydrogenase activity
SD85_01795	COG1012	belongs to the aldehyde dehydrogenase family
SD85_01800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SD85_01805	COG2508	Transcriptional regulator
SD85_01810	COG3689	TIGRFAM TIGR03943 family protein
SD85_01815	COG0701	Predicted permease
SD85_01820	COG2267	carboxylic ester hydrolase activity
SD85_01825	COG0492	ferredoxin-NADP+ reductase activity
SD85_01830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SD85_01830	COG1587	Uroporphyrinogen-III synthase
SD85_01835	COG2146	nitrite reductase [NAD(P)H] activity
SD85_01840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SD85_01845	COG0243	molybdopterin cofactor binding
SD85_01850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SD85_01855	COG2223	nitrite transmembrane transporter activity
SD85_01860	COG1469	GTP cyclohydrolase I activity
SD85_01865	COG1376	ErfK ybiS ycfS ynhG family protein
SD85_01875	COG0523	cobalamin synthesis protein
SD85_01880	COG0765	amino acid transport
SD85_01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SD85_01895	COG1714	RDD family
SD85_01905	COG1846	Transcriptional regulator
SD85_01915	COG3842	ATPase activity
SD85_01920	COG2723	6-phospho-beta-galactosidase activity
SD85_01930	COG3209	COG3209 Rhs family protein
SD85_01935	COG3290	protein histidine kinase activity
SD85_01935	COG0840	transmembrane signaling receptor activity
SD85_01940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SD85_01945	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SD85_01950	COG1733	regulation of RNA biosynthetic process
SD85_01960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_01975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SD85_01980	COG2814	Major facilitator Superfamily
SD85_01990	COG0697	spore germination
SD85_01995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD85_02005	COG2364	Membrane
SD85_02010	COG1126	abc transporter atp-binding protein
SD85_02015	COG0765	amino acid transport
SD85_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SD85_02025	COG0583	DNA-binding transcription factor activity
SD85_02030	COG0163	prenyltransferase activity
SD85_02035	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SD85_02050	COG0596	Alpha beta hydrolase
SD85_02055	COG3104	oligopeptide transport
SD85_02060	COG5434	Belongs to the glycosyl hydrolase 28 family
SD85_02070	COG0697	spore germination
SD85_02080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SD85_02085	COG1136	(ABC) transporter
SD85_02090	COG0577	efflux transmembrane transporter activity
SD85_02095	COG0745	RESPONSE REGULATOR receiver
SD85_02100	COG5002	protein histidine kinase activity
SD85_02100	COG3850	Histidine kinase
SD85_02105	COG0457	Tetratricopeptide repeat
SD85_02120	COG0527	aspartate kinase activity
SD85_02125	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_02130	COG4605	iron ion homeostasis
SD85_02135	COG4604	ABC transporter, ATP-binding protein
SD85_02140	COG4607	ABC-type enterochelin transport system periplasmic component
SD85_02145	COG2814	Major facilitator Superfamily
SD85_02150	COG1309	transcriptional regulator
SD85_02155	COG0778	Nitroreductase
SD85_02160	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SD85_02165	COG0640	Transcriptional regulator
SD85_02170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD85_02175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SD85_02180	COG1012	belongs to the aldehyde dehydrogenase family
SD85_02185	COG4975	Glucose uptake
SD85_02190	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_02195	COG4549	nuclear export factor GLE1
SD85_02200	COG2372	response to copper ion
SD85_02200	COG1276	copper resistance
SD85_02205	COG1349	DNA-binding transcription factor activity
SD85_02215	COG2213	PTS system mannitol-specific
SD85_02220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD85_02225	COG0246	Mannitol dehydrogenase
SD85_02230	COG0473	3-isopropylmalate dehydrogenase activity
SD85_02235	COG0681	Belongs to the peptidase S26 family
SD85_02240	COG0412	Dienelactone hydrolase
SD85_02245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SD85_02255	COG0561	phosphatase activity
SD85_02260	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SD85_02265	COG1914	H( )-stimulated, divalent metal cation uptake system
SD85_02270	COG4336	lyase activity
SD85_02275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SD85_02280	COG1984	allophanate hydrolase subunit 2
SD85_02285	COG1414	Transcriptional regulator
SD85_02290	COG2755	lipolytic protein G-D-S-L family
SD85_02300	COG2329	Antibiotic biosynthesis monooxygenase
SD85_02305	COG0768	penicillin binding
SD85_02310	COG4989	oxidoreductase activity
SD85_02315	COG3711	transcriptional antiterminator
SD85_02320	COG0318	PFAM AMP-dependent synthetase and ligase
SD85_02325	COG2226	methyltransferase
SD85_02330	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_02335	COG1917	Cupin 2, conserved barrel domain protein
SD85_02340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD85_02345	COG3871	stress protein (general stress protein 26)
SD85_02355	COG2814	Major facilitator Superfamily
SD85_02360	COG1522	sequence-specific DNA binding
SD85_02365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SD85_02365	COG0551	DNA topoisomerase type I activity
SD85_02370	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SD85_02375	COG3706	GGDEF domain
SD85_02380	COG5298	Protein conserved in bacteria
SD85_02385	COG1215	transferase activity, transferring glycosyl groups
SD85_02395	COG0531	amino acid
SD85_02400	COG0494	nUDIX hydrolase
SD85_02405	COG0028	Belongs to the TPP enzyme family
SD85_02415	COG1914	H( )-stimulated, divalent metal cation uptake system
SD85_02420	COG2261	transglycosylase associated protein
SD85_02425	COG4876	unkown
SD85_02430	COG2217	Heavy metal translocating P-type atpase
SD85_02435	COG3729	General stress protein
SD85_02445	COG2329	Antibiotic biosynthesis monooxygenase
SD85_02450	COG3546	catalase activity
SD85_02455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SD85_02460	COG3290	protein histidine kinase activity
SD85_02465	COG4565	transcriptional regulatory protein
SD85_02470	COG1301	dicarboxylic acid transport
SD85_02475	COG0628	permease
SD85_02480	COG1301	dicarboxylic acid transport
SD85_02485	COG1131	(ABC) transporter
SD85_02490	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
SD85_02500	COG1960	acyl-CoA dehydrogenase activity
SD85_02515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SD85_02520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_02525	COG1181	Belongs to the D-alanine--D-alanine ligase family
SD85_02530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SD85_02535	COG0513	Belongs to the DEAD box helicase family
SD85_02540	COG3402	PFAM membrane-flanked domain
SD85_02545	COG3428	Bacterial PH domain
SD85_02550	COG0705	Rhomboid family
SD85_02555	COG0736	holo-[acyl-carrier-protein] synthase activity
SD85_02560	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SD85_02565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SD85_02570	COG0864	Transcriptional regulator
SD85_02575	COG2337	Toxic component of a toxin-antitoxin (TA) module
SD85_02580	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_02585	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_02590	COG2172	sigma factor antagonist activity
SD85_02595	COG2208	phosphoserine phosphatase activity
SD85_02600	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_02605	COG2172	sigma factor antagonist activity
SD85_02610	COG1191	sigma factor activity
SD85_02615	COG2208	phosphoserine phosphatase activity
SD85_02620	COG2183	response to ionizing radiation
SD85_02630	COG3091	SprT-like family
SD85_02675	COG0789	Transcriptional regulator
SD85_02680	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_02685	COG0667	Aldo Keto reductase
SD85_02690	COG4221	oxidoreductase activity
SD85_02695	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_02705	COG4221	oxidoreductase activity
SD85_02710	COG3239	Fatty acid desaturase
SD85_02715	COG1278	Cold shock
SD85_02720	COG1329	Transcriptional regulator
SD85_02730	COG1396	sequence-specific DNA binding
SD85_02735	COG3708	Transcriptional regulator
SD85_02735	COG2207	Transcriptional regulator
SD85_02745	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SD85_02760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SD85_02765	COG1522	sequence-specific DNA binding
SD85_02770	COG0697	spore germination
SD85_02775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD85_02780	COG2030	dehydratase
SD85_02785	COG3545	Serine hydrolase
SD85_02790	COG1733	regulation of RNA biosynthetic process
SD85_02795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD85_02805	COG0640	Transcriptional regulator
SD85_02810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SD85_02815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SD85_02820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD85_02825	COG0697	spore germination
SD85_02830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD85_02835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SD85_02840	COG0640	Transcriptional regulator
SD85_02845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SD85_02860	COG4585	Histidine kinase
SD85_02865	COG2197	response regulator
SD85_02870	COG2409	Drug exporters of the RND superfamily
SD85_02880	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SD85_02885	COG1114	Component of the transport system for branched-chain amino acids
SD85_02895	COG1811	Na channel or pump
SD85_02900	COG0789	Transcriptional regulator
SD85_02900	COG4978	Transcriptional regulator
SD85_02905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SD85_02910	COG0778	Nitroreductase
SD85_02915	COG0346	lactoylglutathione lyase activity
SD85_02920	COG2259	Doxx family
SD85_02925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_02930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD85_02950	COG2323	membrane
SD85_02955	COG0071	Belongs to the small heat shock protein (HSP20) family
SD85_02970	COG1309	transcriptional regulator
SD85_02980	COG0456	acetyltransferase
SD85_02990	COG0673	inositol 2-dehydrogenase activity
SD85_02995	COG1609	Transcriptional regulator
SD85_03000	COG2814	Major facilitator Superfamily
SD85_03005	COG2814	Major facilitator Superfamily
SD85_03010	COG2814	Major facilitator Superfamily
SD85_03020	COG2814	Major facilitator Superfamily
SD85_03035	COG1113	amino acid transport
SD85_03040	COG2318	DinB family
SD85_03045	COG1846	Transcriptional regulator
SD85_03050	COG1033	growth of symbiont in host cell
SD85_03050	COG2409	Drug exporters of the RND superfamily
SD85_03055	COG0778	Nitroreductase
SD85_03060	COG1846	Transcriptional regulator
SD85_03065	COG1396	sequence-specific DNA binding
SD85_03080	COG2814	Major facilitator Superfamily
SD85_03085	COG0730	response to heat
SD85_03090	COG1802	Transcriptional regulator
SD85_03095	COG1388	LysM domain
SD85_03095	COG3858	chitin binding
SD85_03100	COG1819	glycosyl
SD85_03115	COG1785	Belongs to the alkaline phosphatase family
SD85_03125	COG0454	-acetyltransferase
SD85_03130	COG1078	dGTPase activity
SD85_03135	COG1388	LysM domain
SD85_03140	COG2814	Major facilitator Superfamily
SD85_03145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SD85_03150	COG1447	Phosphotransferase system cellobiose-specific component IIA
SD85_03155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SD85_03160	COG2723	6-phospho-beta-galactosidase activity
SD85_03165	COG2188	Transcriptional regulator
SD85_03170	COG1940	carbohydrate kinase activity
SD85_03175	COG1482	cell wall glycoprotein biosynthetic process
SD85_03180	COG4124	Belongs to the glycosyl hydrolase 26 family
SD85_03225	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SD85_03230	COG0802	atpase or kinase
SD85_03235	COG1214	PFAM Peptidase M22, glycoprotease
SD85_03240	COG0456	acetyltransferase
SD85_03245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SD85_03250	COG0488	(ABC) transporter
SD85_03255	COG0315	cyclic pyranopterin monophosphate synthase activity
SD85_03260	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SD85_03265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SD85_03270	COG0805	protein transport
SD85_03280	COG1266	CAAX protease self-immunity
SD85_03285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SD85_03290	COG0459	protein refolding
SD85_03295	COG1073	alpha beta
SD85_03300	COG0457	Tetratricopeptide repeat
SD85_03305	COG1063	alcohol dehydrogenase
SD85_03310	COG2211	Major facilitator Superfamily
SD85_03315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SD85_03320	COG1842	Phage shock protein A
SD85_03325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SD85_03330	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SD85_03335	COG4260	virion core protein, lumpy skin disease virus
SD85_03345	COG2814	Major facilitator Superfamily
SD85_03350	COG1063	alcohol dehydrogenase
SD85_03355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SD85_03360	COG0823	Involved in the tonB-independent uptake of proteins
SD85_03370	COG2801	Transposase and inactivated derivatives
SD85_03385	COG2267	carboxylic ester hydrolase activity
SD85_03395	COG2132	Multicopper oxidase
SD85_03400	COG1113	amino acid transport
SD85_03410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SD85_03415	COG0714	Associated with various cellular activities
SD85_03420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
SD85_03425	COG1305	Transglutaminase-like
SD85_03430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SD85_03430	COG0519	Catalyzes the synthesis of GMP from XMP
SD85_03435	COG2252	PERMEase
SD85_03440	COG3064	Membrane
SD85_03450	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SD85_03460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SD85_03465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SD85_03470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SD85_03475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SD85_03480	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SD85_03485	COG0047	phosphoribosylformylglycinamidine synthase activity
SD85_03490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SD85_03495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SD85_03500	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SD85_03505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SD85_03510	COG0138	bifunctional purine biosynthesis protein purh
SD85_03515	COG0151	Belongs to the GarS family
SD85_03520	COG1522	sequence-specific DNA binding
SD85_03525	COG0531	amino acid
SD85_03535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SD85_03540	COG1470	cell adhesion involved in biofilm formation
SD85_03545	COG4496	protein, YerC YecD
SD85_03550	COG0069	glutamate synthase activity
SD85_03555	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
SD85_03560	COG0210	DNA helicase
SD85_03565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SD85_03570	COG4851	CamS sex pheromone cAM373 precursor
SD85_03580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SD85_03585	COG1285	pathogenesis
SD85_03590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SD85_03595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SD85_03600	COG0154	amidase activity
SD85_03605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SD85_03610	COG1309	transcriptional regulator
SD85_03615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SD85_03620	COG1597	lipid kinase activity
SD85_03625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SD85_03630	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SD85_03635	COG0732	type I restriction modification DNA specificity domain
SD85_03640	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SD85_03660	COG5444	nuclease activity
SD85_03665	COG3391	amine dehydrogenase activity
SD85_03670	COG0457	Tetratricopeptide repeat
SD85_03680	COG0217	transcriptional regulatory protein
SD85_03690	COG1309	transcriptional regulator
SD85_03695	COG3631	Ketosteroid isomerase-related protein
SD85_03700	COG0702	epimerase
SD85_03705	COG2159	amidohydrolase
SD85_03710	COG1309	transcriptional regulator
SD85_03725	COG3546	catalase activity
SD85_03730	COG0454	-acetyltransferase
SD85_03740	COG5578	integral membrane protein
SD85_03745	COG2972	Histidine kinase
SD85_03750	COG2207	Transcriptional regulator
SD85_03750	COG4753	response regulator
SD85_03755	COG1653	transport
SD85_03760	COG1175	transmembrane transport
SD85_03765	COG0395	ABC-type sugar transport system, permease component
SD85_03770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SD85_03775	COG2207	Transcriptional regulator
SD85_03780	COG2755	lipolytic protein G-D-S-L family
SD85_03790	COG5578	integral membrane protein
SD85_03795	COG3401	FG-GAP repeat protein
SD85_03800	COG3401	FG-GAP repeat protein
SD85_03805	COG2755	lipolytic protein G-D-S-L family
SD85_03810	COG1874	Beta-galactosidase
SD85_03820	COG1653	transport
SD85_03825	COG4209	transmembrane transport
SD85_03830	COG0395	ABC-type sugar transport system, permease component
SD85_03835	COG1486	melibiose metabolic process
SD85_03840	COG2323	membrane
SD85_03845	COG2329	Antibiotic biosynthesis monooxygenase
SD85_03850	COG0346	lactoylglutathione lyase activity
SD85_03860	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_03865	COG5583	Uncharacterized small protein (DUF2292)
SD85_03870	COG0670	Belongs to the BI1 family
SD85_03875	COG1846	Transcriptional regulator
SD85_03880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SD85_03890	COG2124	cytochrome p450
SD85_03890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SD85_03895	COG1368	sulfuric ester hydrolase activity
SD85_03900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SD85_03905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SD85_03910	COG1442	glycosyl transferase family 8
SD85_03915	COG1216	Glycosyl transferase, family 2
SD85_03920	COG1442	glycosyl transferase family 8
SD85_03925	COG2223	nitrite transmembrane transporter activity
SD85_03930	COG1011	Hydrolase
SD85_03935	COG0531	amino acid
SD85_03940	COG1012	belongs to the aldehyde dehydrogenase family
SD85_03945	COG0840	transmembrane signaling receptor activity
SD85_03950	COG0488	(ABC) transporter
SD85_03960	COG0789	Transcriptional regulator
SD85_03965	COG2814	Major facilitator Superfamily
SD85_03980	COG0488	(ABC) transporter
SD85_03985	COG0513	Belongs to the DEAD box helicase family
SD85_03990	COG0456	acetyltransferase
SD85_03995	COG2130	NADP-dependent
SD85_04000	COG1120	ATPase activity
SD85_04005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_04015	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SD85_04030	COG3866	Pectate lyase
SD85_04035	COG0471	metal ion transport
SD85_04040	COG3290	protein histidine kinase activity
SD85_04045	COG4565	transcriptional regulatory protein
SD85_04050	COG3181	Tripartite tricarboxylate transporter family receptor
SD85_04055	COG2851	Citrate transporter
SD85_04060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD85_04065	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
SD85_04070	COG1254	Belongs to the acylphosphatase family
SD85_04075	COG2258	MOSC domain
SD85_04095	COG0024	Methionine aminopeptidase
SD85_04100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_04100	COG1263	PTS System
SD85_04105	COG1368	sulfuric ester hydrolase activity
SD85_04115	COG1115	amino acid carrier protein
SD85_04120	COG0531	amino acid
SD85_04135	COG0697	spore germination
SD85_04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_04140	COG1263	PTS System
SD85_04145	COG0366	Alpha amylase catalytic
SD85_04150	COG2188	Transcriptional regulator
SD85_04155	COG0778	Nitroreductase
SD85_04160	COG0737	Belongs to the 5'-nucleotidase family
SD85_04165	COG0693	protein deglycase activity
SD85_04170	COG2814	Major facilitator Superfamily
SD85_04175	COG4840	Belongs to the UPF0435 family
SD85_04180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SD85_04185	COG4980	gas vesicle protein
SD85_04190	COG1295	ribonuclease BN
SD85_04200	COG0477	Major facilitator Superfamily
SD85_04210	COG0387	Pfam Sodium calcium exchanger
SD85_04220	COG0668	transmembrane transport
SD85_04225	COG0535	radical SAM domain protein
SD85_04235	COG0726	polysaccharide deacetylase
SD85_04240	COG2084	Dehydrogenase
SD85_04245	COG0598	Magnesium transport protein CorA
SD85_04250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SD85_04260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SD85_04265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SD85_04275	COG4637	Psort location Cytoplasmic, score
SD85_04285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SD85_04290	COG0022	dehydrogenase e1 component
SD85_04295	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD85_04300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SD85_04305	COG3284	Transcriptional regulator
SD85_04315	COG1742	UPF0060 membrane protein
SD85_04335	COG4842	Belongs to the WXG100 family
SD85_04340	COG1486	melibiose metabolic process
SD85_04345	COG1737	Transcriptional regulator
SD85_04350	COG1263	PTS System
SD85_04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_04355	COG1132	(ABC) transporter
SD85_04360	COG1132	(ABC) transporter
SD85_04365	COG2259	Doxx family
SD85_04370	COG2514	catechol 2,3-dioxygenase activity
SD85_04375	COG4585	Histidine kinase
SD85_04380	COG2197	response regulator
SD85_04385	COG1131	(ABC) transporter
SD85_04390	COG0842	Transport permease protein
SD85_04390	COG1511	domain protein
SD85_04395	COG0842	Transport permease protein
SD85_04405	COG1695	Transcriptional regulator
SD85_04410	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SD85_04415	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
SD85_04420	COG2318	DinB family
SD85_04425	COG2814	Major facilitator Superfamily
SD85_04430	COG1846	Transcriptional regulator
SD85_04435	COG0392	lysyltransferase activity
SD85_04435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SD85_04440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD85_04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_04450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_04460	COG0778	Nitroreductase
SD85_04475	COG1090	epimerase
SD85_04480	COG2137	regulation of response to DNA damage stimulus
SD85_04495	COG2814	Major facilitator Superfamily
SD85_04510	COG3103	Sh3 type 3 domain protein
SD85_04515	COG5658	integral membrane protein
SD85_04520	COG0596	Alpha beta hydrolase
SD85_04525	COG0463	Glycosyl transferase, family 2
SD85_04530	COG4485	Bacterial membrane protein, YfhO
SD85_04535	COG1988	membrane-bound metal-dependent
SD85_04540	COG1194	a g-specific adenine glycosylase
SD85_04550	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_04565	COG3557	Belongs to the UPF0374 family
SD85_04570	COG1132	(ABC) transporter
SD85_04575	COG4129	membrane
SD85_04580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SD85_04585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SD85_04590	COG0735	belongs to the Fur family
SD85_04710	COG4326	sporulation control protein
SD85_04720	COG5577	PFAM Coat F domain
SD85_04725	COG3340	Belongs to the peptidase S51 family
SD85_04730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SD85_04740	COG0753	catalase activity
SD85_04745	COG1116	anion transmembrane transporter activity
SD85_04750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SD85_04755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SD85_04760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SD85_04770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SD85_04780	COG1476	TRANSCRIPTIONal
SD85_04790	COG3382	B3 4 domain protein
SD85_04795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SD85_04805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SD85_04810	COG0789	Transcriptional regulator
SD85_04815	COG1664	Polymer-forming cytoskeletal
SD85_04820	COG1664	Polymer-forming cytoskeletal
SD85_04825	COG2766	serine protein kinase
SD85_04830	COG2718	Belongs to the UPF0229 family
SD85_04835	COG1846	Transcriptional regulator
SD85_04840	COG1566	PFAM secretion protein HlyD family protein
SD85_04845	COG2814	Major facilitator Superfamily
SD85_04850	COG0655	NAD(P)H dehydrogenase (quinone) activity
SD85_04865	COG1725	Transcriptional regulator
SD85_04870	COG1131	(ABC) transporter
SD85_04875	COG1131	(ABC) transporter
SD85_04885	COG1278	Cold shock
SD85_04890	COG1464	Belongs to the NlpA lipoprotein family
SD85_04895	COG3706	GGDEF domain
SD85_04900	COG1823	symporter activity
SD85_04920	COG5577	PFAM Coat F domain
SD85_04925	COG0737	Belongs to the 5'-nucleotidase family
SD85_04925	COG4085	toxin activity
SD85_04925	COG1525	nuclease
SD85_04930	COG3764	Sortase (surface protein transpeptidase)
SD85_04935	COG0564	pseudouridine synthase activity
SD85_04945	COG0517	IMP dehydrogenase activity
SD85_04950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SD85_04955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SD85_04955	COG3153	acetyltransferase
SD85_04965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SD85_04970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SD85_04975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SD85_04980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SD85_04985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SD85_04990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SD85_04995	COG2203	Gaf domain
SD85_04995	COG4585	Histidine kinase
SD85_05000	COG2197	response regulator
SD85_05005	COG0431	NADPH-dependent FMN reductase
SD85_05020	COG0791	NLP P60 protein
SD85_05020	COG1388	LysM domain
SD85_05025	COG1959	2 iron, 2 sulfur cluster binding
SD85_05030	COG0668	transmembrane transport
SD85_05035	COG2719	SpoVR family
SD85_05040	COG1785	Belongs to the alkaline phosphatase family
SD85_05045	COG0791	NLP P60 protein
SD85_05045	COG1388	LysM domain
SD85_05050	COG0583	DNA-binding transcription factor activity
SD85_05055	COG0372	Belongs to the citrate synthase family
SD85_05060	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_05065	COG0531	amino acid
SD85_05070	COG0733	neurotransmitter:sodium symporter activity
SD85_05075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD85_05080	COG0456	acetyltransferase
SD85_05095	COG1595	DNA-templated transcription, initiation
SD85_05100	COG0667	Aldo Keto reductase
SD85_05105	COG0204	Acyl-transferase
SD85_05110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SD85_05120	COG1253	flavin adenine dinucleotide binding
SD85_05125	COG0789	Transcriptional regulator
SD85_05130	COG0436	Aminotransferase
SD85_05135	COG1253	flavin adenine dinucleotide binding
SD85_05140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SD85_05145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SD85_05150	COG0584	glycerophosphoryl diester phosphodiesterase
SD85_05160	COG0668	transmembrane transport
SD85_05165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SD85_05170	COG0726	polysaccharide deacetylase
SD85_05175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SD85_05180	COG1757	Na H antiporter
SD85_05185	COG0589	response to stress
SD85_05195	COG1132	(ABC) transporter
SD85_05200	COG1132	(ABC) transporter
SD85_05205	COG0702	epimerase
SD85_05225	COG0189	ligase activity
SD85_05230	COG0189	ligase activity
SD85_05235	COG4399	Belongs to the UPF0754 family
SD85_05240	COG3679	Belongs to the UPF0342 family
SD85_05245	COG4335	DNA alkylation repair
SD85_05250	COG0561	phosphatase activity
SD85_05255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SD85_05260	COG0475	glutathione-regulated potassium exporter activity
SD85_05265	COG0490	domain, Protein
SD85_05275	COG1024	Enoyl-CoA hydratase
SD85_05285	COG4152	abc transporter atp-binding protein
SD85_05290	COG1668	transmembrane transport
SD85_05295	COG0420	3'-5' exonuclease activity
SD85_05300	COG4717	serine-type aminopeptidase activity
SD85_05305	COG3481	metal-dependent phosphohydrolase, HD sub domain
SD85_05315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SD85_05340	COG1846	Transcriptional regulator
SD85_05345	COG4980	gas vesicle protein
SD85_05360	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SD85_05365	COG0537	adenosine 5'-monophosphoramidase activity
SD85_05370	COG1131	(ABC) transporter
SD85_05375	COG4473	ABC transporter
SD85_05385	COG1473	amidohydrolase
SD85_05390	COG3069	C4-dicarboxylate transmembrane transporter activity
SD85_05400	COG2329	Antibiotic biosynthesis monooxygenase
SD85_05405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SD85_05410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SD85_05425	COG1309	transcriptional regulator
SD85_05430	COG1511	domain protein
SD85_05435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SD85_05440	COG4377	Putative membrane peptidase family (DUF2324)
SD85_05450	COG1363	Peptidase, m42
SD85_05455	COG4405	Protein conserved in bacteria
SD85_05460	COG1301	dicarboxylic acid transport
SD85_05470	COG1234	tRNA 3'-trailer cleavage
SD85_05475	COG0095	Lipoate-protein ligase
SD85_05480	COG0702	epimerase
SD85_05485	COG0318	PFAM AMP-dependent synthetase and ligase
SD85_05495	COG0501	Belongs to the peptidase M48B family
SD85_05505	COG0456	acetyltransferase
SD85_05510	COG0604	alcohol dehydrogenase
SD85_05515	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SD85_05520	COG0406	alpha-ribazole phosphatase activity
SD85_05525	COG0183	Belongs to the thiolase family
SD85_05530	COG0318	PFAM AMP-dependent synthetase and ligase
SD85_05535	COG1268	BioY protein
SD85_05540	COG0840	transmembrane signaling receptor activity
SD85_05545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SD85_05545	COG0723	plastoquinol--plastocyanin reductase activity
SD85_05550	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_05560	COG4903	ComK protein
SD85_05565	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_05575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SD85_05590	COG0398	Pfam SNARE associated Golgi protein
SD85_05595	COG0681	Belongs to the peptidase S26 family
SD85_05600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SD85_05605	COG1846	Transcriptional regulator
SD85_05615	COG0738	Major facilitator superfamily
SD85_05620	COG0673	inositol 2-dehydrogenase activity
SD85_05625	COG0561	phosphatase activity
SD85_05630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SD85_05635	COG1609	Transcriptional regulator
SD85_05640	COG3180	Ammonia monooxygenase
SD85_05645	COG2814	Major facilitator Superfamily
SD85_05645	COG0477	Major facilitator Superfamily
SD85_05650	COG4533	DNA binding
SD85_05660	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SD85_05665	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SD85_05670	COG1074	ATP-dependent DNA helicase activity
SD85_05675	COG0420	3'-5' exonuclease activity
SD85_05680	COG0419	ATPase involved in DNA repair
SD85_05685	COG1403	HNH endonuclease
SD85_05725	COG5337	Spore coat protein CotH
SD85_05730	COG0179	Fumarylacetoacetate (FAA) hydrolase
SD85_05740	COG1404	Belongs to the peptidase S8 family
SD85_05750	COG0367	asparagine synthase
SD85_05755	COG2318	DinB family
SD85_05760	COG1562	ergosterol biosynthetic process
SD85_05765	COG0534	Mate efflux family protein
SD85_05770	COG2207	Transcriptional regulator
SD85_05770	COG1917	Cupin 2, conserved barrel domain protein
SD85_05775	COG1609	Transcriptional regulator
SD85_05780	COG0673	inositol 2-dehydrogenase activity
SD85_05785	COG2318	DinB family
SD85_05790	COG1279	arginine transmembrane transporter activity
SD85_05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD85_05800	COG1357	PFAM Pentapeptide repeats (8 copies)
SD85_05805	COG2267	carboxylic ester hydrolase activity
SD85_05810	COG0529	Catalyzes the synthesis of activated sulfate
SD85_05815	COG2046	Belongs to the sulfate adenylyltransferase family
SD85_05820	COG0175	sulfate reduction
SD85_05825	COG2045	Belongs to the ComB family
SD85_05830	COG1809	phosphosulfolactate synthase activity
SD85_05835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD85_05840	COG4948	Mandelate Racemase Muconate Lactonizing
SD85_05845	COG2814	Major facilitator Superfamily
SD85_05850	COG0454	-acetyltransferase
SD85_05855	COG2153	protein acetylation
SD85_05860	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SD85_05860	COG0646	methionine synthase
SD85_05865	COG1666	GTP binding
SD85_05870	COG2996	Protein conserved in bacteria
SD85_05880	COG1307	EDD domain protein, DegV family
SD85_05885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD85_05905	COG0561	phosphatase activity
SD85_05910	COG1073	alpha beta
SD85_05915	COG2151	metal-sulfur cluster biosynthetic enzyme
SD85_05925	COG0277	FAD linked oxidase domain protein
SD85_05930	COG2271	Major facilitator Superfamily
SD85_05935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SD85_05950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SD85_05955	COG0505	Belongs to the CarA family
SD85_05960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SD85_05965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SD85_05980	COG2267	carboxylic ester hydrolase activity
SD85_05990	COG1744	ABC transporter substrate-binding protein PnrA-like
SD85_06005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SD85_06010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SD85_06015	COG5504	Zn-dependent protease
SD85_06020	COG0444	Belongs to the ABC transporter superfamily
SD85_06025	COG4608	Belongs to the ABC transporter superfamily
SD85_06035	COG0601	transmembrane transport
SD85_06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SD85_06050	COG0180	Tryptophanyl-tRNA synthetase
SD85_06055	COG4166	transmembrane transport
SD85_06060	COG0601	transmembrane transport
SD85_06065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SD85_06070	COG0444	Belongs to the ABC transporter superfamily
SD85_06075	COG4608	Belongs to the ABC transporter superfamily
SD85_06080	COG2814	Major facilitator Superfamily
SD85_06085	COG0456	acetyltransferase
SD85_06090	COG1393	Belongs to the ArsC family
SD85_06095	COG0861	Integral membrane protein TerC family
SD85_06100	COG4862	establishment of competence for transformation
SD85_06105	COG4469	Competence protein
SD85_06110	COG1164	Oligoendopeptidase f
SD85_06130	COG2346	COG2346, Truncated hemoglobins
SD85_06135	COG0741	lytic transglycosylase activity
SD85_06140	COG4116	CYTH
SD85_06150	COG2357	RelA SpoT domain protein
SD85_06155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SD85_06160	COG0564	pseudouridine synthase activity
SD85_06165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SD85_06170	COG0475	glutathione-regulated potassium exporter activity
SD85_06170	COG0569	domain protein
SD85_06175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SD85_06180	COG0352	thiamine-phosphate diphosphorylase activity
SD85_06185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SD85_06190	COG2104	thiamine diphosphate biosynthetic process
SD85_06195	COG2022	thiamine diphosphate biosynthetic process
SD85_06200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SD85_06205	COG0351	phosphomethylpyrimidine kinase
SD85_06210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SD85_06270	COG0210	DNA helicase
SD85_06280	COG2153	protein acetylation
SD85_06285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SD85_06290	COG2382	esterase
SD85_06295	COG0626	cystathionine gamma-synthase activity
SD85_06300	COG0626	cystathionine gamma-synthase activity
SD85_06310	COG5505	Protein of unknown function (DUF819)
SD85_06335	COG0457	Tetratricopeptide repeat
SD85_06365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD85_06365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD85_06365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD85_06370	COG1482	cell wall glycoprotein biosynthetic process
SD85_06390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SD85_06410	COG0109	protoheme IX farnesyltransferase activity
SD85_06420	COG0726	polysaccharide deacetylase
SD85_06440	COG5504	Zn-dependent protease
SD85_06445	COG2205	protein histidine kinase activity
SD85_06455	COG3383	formate dehydrogenase (NAD+) activity
SD85_06460	COG2427	Protein of unknown function (DUF1641)
SD85_06470	COG1051	belongs to the nudix hydrolase family
SD85_06480	COG2124	cytochrome p450
SD85_06485	COG1819	glycosyl
SD85_06495	COG1587	Uroporphyrinogen-III synthase
SD85_06500	COG0390	transport system, permease component
SD85_06505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SD85_06510	COG0697	spore germination
SD85_06515	COG4297	protein containing double-stranded beta helix domain
SD85_06525	COG1252	NADH dehydrogenase
SD85_06530	COG1904	glucuronate isomerase
SD85_06535	COG2211	Major facilitator Superfamily
SD85_06540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SD85_06545	COG1063	alcohol dehydrogenase
SD85_06550	COG1312	Catalyzes the dehydration of D-mannonate
SD85_06555	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_06560	COG2271	Major facilitator Superfamily
SD85_06565	COG1609	Transcriptional regulator
SD85_06570	COG0246	Mannitol dehydrogenase
SD85_06575	COG2721	sulfolactate sulfo-lyase activity
SD85_06580	COG0730	response to heat
SD85_06585	COG2318	DinB family
SD85_06590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SD85_06595	COG0457	Tetratricopeptide repeat
SD85_06605	COG2350	Protein conserved in bacteria
SD85_06610	COG3409	Peptidoglycan-binding domain 1 protein
SD85_06610	COG5632	N-Acetylmuramoyl-L-alanine amidase
SD85_06610	COG1388	LysM domain
SD85_06620	COG4195	phage-related replication protein
SD85_06625	COG3546	catalase activity
SD85_06630	COG2856	Zn peptidase
SD85_06635	COG1396	sequence-specific DNA binding
SD85_06645	COG1522	sequence-specific DNA binding
SD85_06650	COG1484	DNA-dependent DNA replication
SD85_06675	COG1595	DNA-templated transcription, initiation
SD85_06680	COG3728	DNA packaging
SD85_06680	COG5484	DNA packaging
SD85_06685	COG1783	phage Terminase large subunit
SD85_06690	COG5518	Phage portal protein
SD85_06695	COG0338	D12 class N6 adenine-specific DNA methyltransferase
SD85_06700	COG4653	Phage capsid family
SD85_06750	COG5412	phage tail tape measure protein
SD85_06750	COG3953	SLT domain
SD85_06750	COG3953	SLT domain
SD85_06750	COG5412	phage tail tape measure protein
SD85_06750	COG5412	phage tail tape measure protein
SD85_06750	COG3953	SLT domain
SD85_06755	COG1652	LysM domain
SD85_06760	COG4193	domain, Protein
SD85_06770	COG3628	GPW Gp25 family protein
SD85_06775	COG3299	homolog of phage Mu protein gp47
SD85_06780	COG3778	Protein conserved in bacteria
SD85_06820	COG3409	Peptidoglycan-binding domain 1 protein
SD85_06820	COG5632	N-Acetylmuramoyl-L-alanine amidase
SD85_06835	COG0306	phosphate transporter
SD85_06840	COG1392	Phosphate transport regulator
SD85_06845	COG0531	amino acid
SD85_06850	COG0346	lactoylglutathione lyase activity
SD85_06855	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SD85_06860	COG0463	Glycosyl transferase, family 2
SD85_06870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SD85_06875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SD85_06880	COG2362	D-Aminopeptidase
SD85_06885	COG0601	transmembrane transport
SD85_06890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SD85_06895	COG0444	Belongs to the ABC transporter superfamily
SD85_06900	COG4166	transmembrane transport
SD85_06905	COG1619	proteins homologs of microcin C7 resistance protein MccF
SD85_06910	COG4948	Mandelate Racemase Muconate Lactonizing
SD85_06915	COG0791	NLP P60 protein
SD85_06920	COG4608	Belongs to the ABC transporter superfamily
SD85_06925	COG2706	6-phosphogluconolactonase activity
SD85_06930	COG1834	amidinotransferase
SD85_06935	COG1607	acyl-coa hydrolase
SD85_06940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SD85_06940	COG1017	nitric oxide dioxygenase activity
SD85_06950	COG2323	membrane
SD85_06955	COG2318	DinB family
SD85_06960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD85_06965	COG2076	Multidrug Resistance protein
SD85_06970	COG2076	Multidrug Resistance protein
SD85_06975	COG0788	formyltetrahydrofolate deformylase activity
SD85_06980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SD85_06985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SD85_06990	COG1764	response to oxidative stress
SD85_06995	COG1846	Transcriptional regulator
SD85_07000	COG1764	response to oxidative stress
SD85_07005	COG0457	Tetratricopeptide repeat
SD85_07005	COG0463	Glycosyl transferase, family 2
SD85_07010	COG0590	tRNA wobble adenosine to inosine editing
SD85_07020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SD85_07025	COG1404	Belongs to the peptidase S8 family
SD85_07030	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_07035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SD85_07040	COG1122	ATPase activity
SD85_07045	COG4721	ABC-type cobalt transport system, permease component
SD85_07055	COG0745	RESPONSE REGULATOR receiver
SD85_07060	COG5002	protein histidine kinase activity
SD85_07060	COG3850	Histidine kinase
SD85_07065	COG3212	peptidase
SD85_07070	COG3212	peptidase
SD85_07085	COG2239	Acts as a magnesium transporter
SD85_07090	COG0789	Transcriptional regulator
SD85_07105	COG1846	Transcriptional regulator
SD85_07110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SD85_07115	COG0726	polysaccharide deacetylase
SD85_07120	COG1408	metallophosphoesterase
SD85_07130	COG0463	Glycosyl transferase, family 2
SD85_07135	COG1793	dna ligase
SD85_07135	COG3285	dna ligase
SD85_07140	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SD85_07145	COG3300	MHYT domain
SD85_07145	COG5001	Diguanylate cyclase
SD85_07150	COG0586	Pfam SNARE associated Golgi protein
SD85_07155	COG0861	Integral membrane protein TerC family
SD85_07160	COG1191	sigma factor activity
SD85_07180	COG0501	Belongs to the peptidase M48B family
SD85_07185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SD85_07200	COG3594	Acyltransferase
SD85_07205	COG5002	protein histidine kinase activity
SD85_07210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SD85_07220	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SD85_07225	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
SD85_07230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SD85_07235	COG0436	Aminotransferase
SD85_07240	COG1850	ribulose-bisphosphate carboxylase activity
SD85_07245	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
SD85_07250	COG0235	Class ii aldolase
SD85_07255	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SD85_07260	COG3339	Conserved Protein
SD85_07275	COG3852	Histidine kinase
SD85_07280	COG1846	Transcriptional regulator
SD85_07285	COG1360	Flagellar Motor Protein
SD85_07290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SD85_07295	COG0542	response to heat
SD85_07300	COG3949	Membrane
SD85_07305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SD85_07310	COG0720	synthase
SD85_07315	COG0602	queuosine metabolic process
SD85_07320	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SD85_07335	COG4873	Protein conserved in bacteria
SD85_07350	COG3773	Cell wall hydrolase
SD85_07355	COG2244	polysaccharide biosynthetic process
SD85_07360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_07365	COG2217	Heavy metal translocating P-type atpase
SD85_07375	COG0006	proline dipeptidase activity
SD85_07385	COG1609	Transcriptional regulator
SD85_07390	COG3711	transcriptional antiterminator
SD85_07395	COG2190	(PTS) system
SD85_07395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_07395	COG1263	PTS System
SD85_07400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD85_07405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SD85_07415	COG1533	DNA photolyase activity
SD85_07420	COG0456	acetyltransferase
SD85_07425	COG0840	transmembrane signaling receptor activity
SD85_07430	COG2084	Dehydrogenase
SD85_07435	COG2340	Cysteine-rich secretory protein family
SD85_07440	COG0768	penicillin binding
SD85_07445	COG4191	Histidine kinase
SD85_07450	COG0436	Aminotransferase
SD85_07460	COG0835	chemotaxis
SD85_07460	COG0784	Response regulator, receiver
SD85_07470	COG2814	Major facilitator Superfamily
SD85_07475	COG1376	ErfK ybiS ycfS ynhG family protein
SD85_07480	COG1408	metallophosphoesterase
SD85_07485	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_07490	COG2200	EAL domain
SD85_07500	COG4703	Protein of unknown function (DUF1797)
SD85_07505	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
SD85_07515	COG0517	IMP dehydrogenase activity
SD85_07520	COG0583	DNA-binding transcription factor activity
SD85_07525	COG0716	FMN binding
SD85_07535	COG0716	FMN binding
SD85_07540	COG2171	N-acyltransferase activity
SD85_07545	COG1473	amidohydrolase
SD85_07555	COG0668	transmembrane transport
SD85_07560	COG0450	alkyl hydroperoxide reductase
SD85_07565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_07580	COG0746	molybdenum cofactor guanylyltransferase activity
SD85_07585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SD85_07590	COG0303	'Molybdopterin
SD85_07595	COG1763	Mo-molybdopterin cofactor biosynthetic process
SD85_07600	COG0314	molybdopterin synthase activity
SD85_07605	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SD85_07610	COG1132	(ABC) transporter
SD85_07615	COG1132	(ABC) transporter
SD85_07625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SD85_07630	COG1136	(ABC) transporter
SD85_07635	COG0577	efflux transmembrane transporter activity
SD85_07640	COG1349	DNA-binding transcription factor activity
SD85_07645	COG1105	Belongs to the carbohydrate kinase PfkB family
SD85_07650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD85_07650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD85_07650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD85_07655	COG2801	Transposase and inactivated derivatives
SD85_07665	COG0681	Belongs to the peptidase S26 family
SD85_07675	COG0488	(ABC) transporter
SD85_07680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SD85_07685	COG2309	aminopeptidase activity
SD85_07695	COG1077	Cell shape determining protein MreB Mrl
SD85_07700	COG2002	toxin-antitoxin pair type II binding
SD85_07705	COG3852	Histidine kinase
SD85_07710	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
SD85_07710	COG2105	PFAM AIG2 family protein
SD85_07715	COG0569	domain protein
SD85_07720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SD85_07725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SD85_07735	COG0561	phosphatase activity
SD85_07740	COG0242	peptide deformylase activity
SD85_07750	COG0497	DNA recombination
SD85_07755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SD85_07760	COG0022	dehydrogenase e1 component
SD85_07765	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD85_07770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SD85_07775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_07785	COG2801	Transposase and inactivated derivatives
SD85_07790	COG1982	Orn Lys Arg decarboxylase major
SD85_07795	COG4476	Belongs to the UPF0223 family
SD85_07800	COG4493	Belongs to the UPF0637 family
SD85_07810	COG0483	inositol monophosphate 1-phosphatase activity
SD85_07820	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SD85_07840	COG1595	DNA-templated transcription, initiation
SD85_07870	COG4896	Protein conserved in bacteria
SD85_07880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SD85_07885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SD85_07890	COG2066	Belongs to the glutaminase family
SD85_07895	COG4838	Belongs to the UPF0358 family
SD85_07900	COG0772	Belongs to the SEDS family
SD85_07905	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SD85_07910	COG1612	heme a metabolic process
SD85_07915	COG0109	protoheme IX farnesyltransferase activity
SD85_07920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SD85_07920	COG2010	Cytochrome c
SD85_07925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SD85_07930	COG1845	cytochrome c oxidase, subunit III
SD85_07935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SD85_07940	COG3336	cytochrome c oxidase
SD85_07950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
SD85_07955	COG2340	Cysteine-rich secretory protein family
SD85_07970	COG3679	Belongs to the UPF0342 family
SD85_07975	COG4471	UPF0298 protein
SD85_07980	COG0742	ribosomal rna small subunit methyltransferase
SD85_07985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SD85_07990	COG3314	Sporulation integral membrane protein YlbJ
SD85_07995	COG1752	Esterase of the alpha-beta hydrolase superfamily
SD85_08000	COG3480	Lon protease (S16) C-terminal proteolytic domain
SD85_08005	COG1323	Belongs to the UPF0348 family
SD85_08010	COG1399	metal-binding, possibly nucleic acid-binding protein
SD85_08015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SD85_08025	COG0454	-acetyltransferase
SD85_08030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SD85_08035	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
SD85_08040	COG2001	Belongs to the MraZ family
SD85_08045	COG0275	rRNA processing
SD85_08050	COG4839	cell division protein FtsL
SD85_08065	COG0768	penicillin binding
SD85_08075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SD85_08085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SD85_08090	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SD85_08095	COG0772	Belongs to the SEDS family
SD85_08100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SD85_08105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SD85_08110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SD85_08115	COG3879	Bacterial protein of unknown function (DUF881)
SD85_08120	COG3879	Bacterial protein of unknown function (DUF881)
SD85_08125	COG3856	small basic protein
SD85_08130	COG0849	cell division
SD85_08135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SD85_08140	COG4412	M6 family metalloprotease domain protein
SD85_08140	COG1404	Belongs to the peptidase S8 family
SD85_08150	COG1191	sigma factor activity
SD85_08155	COG1191	sigma factor activity
SD85_08160	COG1119	ATPase activity
SD85_08165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD85_08170	COG1873	PFAM PRC-barrel domain
SD85_08180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SD85_08185	COG1799	cell septum assembly
SD85_08190	COG0762	integral membrane protein
SD85_08195	COG2302	S4 RNA-binding domain
SD85_08200	COG3599	regulation of cell shape
SD85_08205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SD85_08210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SD85_08215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SD85_08220	COG0564	pseudouridine synthase activity
SD85_08225	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SD85_08230	COG2233	PERMEase
SD85_08235	COG0540	Belongs to the ATCase OTCase family
SD85_08240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SD85_08245	COG0505	Belongs to the CarA family
SD85_08250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SD85_08255	COG0543	2 iron, 2 sulfur cluster binding
SD85_08260	COG0167	dihydroorotate dehydrogenase activity
SD85_08265	COG0284	orotidine-5'-phosphate decarboxylase activity
SD85_08270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SD85_08280	COG0175	sulfate reduction
SD85_08285	COG0306	phosphate transporter
SD85_08290	COG2046	Belongs to the sulfate adenylyltransferase family
SD85_08295	COG0529	Catalyzes the synthesis of activated sulfate
SD85_08300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SD85_08305	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
SD85_08310	COG1648	precorrin-2 dehydrogenase activity
SD85_08320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SD85_08325	COG1561	YicC-like family, N-terminal region
SD85_08330	COG2052	Domain of unknown function (DUF370)
SD85_08335	COG0194	GDP metabolic process
SD85_08340	COG1758	RNA polymerase activity
SD85_08345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SD85_08350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SD85_08355	COG0242	peptide deformylase activity
SD85_08360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SD85_08365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SD85_08365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SD85_08370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SD85_08375	COG0631	protein serine/threonine phosphatase activity
SD85_08380	COG0515	serine threonine protein kinase
SD85_08380	COG2815	serine threonine protein kinase
SD85_08385	COG1162	GTPase activity
SD85_08390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SD85_08395	COG1564	THIamine pyrophosphokinase
SD85_08405	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SD85_08410	COG1302	Protein conserved in bacteria
SD85_08415	COG1461	Dihydroxyacetone kinase
SD85_08420	COG1760	l-serine dehydratase
SD85_08425	COG1760	l-serine dehydratase
SD85_08430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SD85_08435	COG2050	protein possibly involved in aromatic compounds catabolism
SD85_08435	COG1349	DNA-binding transcription factor activity
SD85_08440	COG0416	fatty acid biosynthetic process
SD85_08445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SD85_08450	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_08455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SD85_08460	COG0571	ribonuclease III activity
SD85_08465	COG1196	nuclear chromosome segregation
SD85_08470	COG0552	protein localization to endoplasmic reticulum
SD85_08480	COG2801	Transposase and inactivated derivatives
SD85_08490	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SD85_08495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SD85_08500	COG0228	four-way junction DNA binding
SD85_08505	COG1837	Belongs to the UPF0109 family
SD85_08515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SD85_08520	COG0336	Belongs to the RNA methyltransferase TrmD family
SD85_08525	COG0335	large ribosomal subunit rRNA binding
SD85_08535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SD85_08545	COG2257	FlhB HrpN YscU SpaS Family
SD85_08550	COG0045	succinate-CoA ligase (ADP-forming) activity
SD85_08555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SD85_08560	COG0758	DNA mediated transformation
SD85_08565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SD85_08570	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SD85_08575	COG4974	Belongs to the 'phage' integrase family
SD85_08580	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SD85_08590	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SD85_08595	COG1815	bacterial-type flagellum-dependent cell motility
SD85_08600	COG1558	bacterial-type flagellum-dependent cell motility
SD85_08605	COG1677	Flagellar hook-basal body complex protein FliE
SD85_08610	COG1766	The M ring may be actively involved in energy transduction
SD85_08615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SD85_08620	COG1317	bacterial-type flagellum organization
SD85_08625	COG1157	protein secretion by the type III secretion system
SD85_08630	COG2882	bacterial-type flagellum organization
SD85_08635	COG3334	PFAM MgtE intracellular
SD85_08640	COG3144	bacterial-type flagellum assembly
SD85_08645	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SD85_08650	COG4786	Flagellar basal body rod
SD85_08655	COG1582	Flagellar protein (FlbD)
SD85_08660	COG1580	Controls the rotational direction of flagella during chemotaxis
SD85_08665	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SD85_08670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SD85_08670	COG1776	CheC inhibitor of MCP methylation
SD85_08675	COG2201	protein-glutamate methylesterase activity
SD85_08680	COG3190	flagellar
SD85_08685	COG1338	Plays a role in the flagellum-specific transport system
SD85_08690	COG1987	bacterial-type flagellum assembly
SD85_08695	COG1684	flagellar biosynthetic protein fliR
SD85_08700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SD85_08705	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SD85_08710	COG1419	protein localization to endoplasmic reticulum
SD85_08715	COG0455	bacterial-type flagellum organization
SD85_08720	COG2201	protein-glutamate methylesterase activity
SD85_08725	COG2198	Histidine kinase
SD85_08725	COG0643	Histidine kinase
SD85_08730	COG0835	chemotaxis
SD85_08735	COG1776	CheC inhibitor of MCP methylation
SD85_08740	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SD85_08745	COG1191	sigma factor activity
SD85_08755	COG0052	Belongs to the universal ribosomal protein uS2 family
SD85_08760	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SD85_08765	COG0528	UMP kinase activity
SD85_08770	COG0233	cytoplasmic translational termination
SD85_08775	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SD85_08780	COG4589	Belongs to the CDS family
SD85_08785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SD85_08790	COG0750	zinc metalloprotease
SD85_08795	COG0442	prolyl-tRNA aminoacylation
SD85_08800	COG2176	DNA-directed DNA polymerase activity
SD85_08805	COG0779	Required for maturation of 30S ribosomal subunits
SD85_08810	COG0195	Participates in both transcription termination and antitermination
SD85_08815	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SD85_08820	COG1358	cellular component organization or biogenesis
SD85_08825	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SD85_08830	COG1550	Protein conserved in bacteria
SD85_08835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SD85_08840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SD85_08845	COG0196	riboflavin kinase activity
SD85_08850	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SD85_08855	COG1185	polyribonucleotide nucleotidyltransferase activity
SD85_08860	COG0726	polysaccharide deacetylase
SD85_08865	COG0612	Peptidase, M16
SD85_08870	COG1873	PFAM PRC-barrel domain
SD85_08875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SD85_08880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SD85_08885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SD85_08890	COG0527	aspartate kinase activity
SD85_08895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SD85_08900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SD85_08905	COG0740	serine-type endopeptidase activity
SD85_08915	COG4980	gas vesicle protein
SD85_08915	COG1674	ftsk spoiiie
SD85_08920	COG2188	Transcriptional regulator
SD85_08925	COG2814	Major facilitator Superfamily
SD85_08930	COG0612	Peptidase, M16
SD85_08935	COG0612	Peptidase, M16
SD85_08940	COG0300	oxidoreductase activity
SD85_08955	COG1426	Protein conserved in bacteria
SD85_08960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SD85_08965	COG1546	Belongs to the CinA family
SD85_08965	COG1058	Belongs to the CinA family
SD85_08970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SD85_08975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SD85_08980	COG1418	mRNA catabolic process
SD85_08985	COG1692	metallophosphoesterase
SD85_08990	COG2359	stage V sporulation protein S
SD85_08995	COG1063	alcohol dehydrogenase
SD85_09000	COG0156	8-amino-7-oxononanoate synthase activity
SD85_09005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SD85_09010	COG4550	Control of competence regulator ComK, YlbF/YmcA
SD85_09020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SD85_09025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SD85_09050	COG3226	Transcriptional regulator
SD85_09055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD85_09065	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SD85_09070	COG3321	synthase
SD85_09075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SD85_09075	COG2070	2-Nitropropane dioxygenase
SD85_09080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SD85_09085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SD85_09090	COG3425	synthase
SD85_09095	COG1024	Enoyl-CoA hydratase
SD85_09100	COG1024	Enoyl-CoA hydratase
SD85_09105	COG0300	oxidoreductase activity
SD85_09105	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_09105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_09105	COG0318	PFAM AMP-dependent synthetase and ligase
SD85_09105	COG3321	synthase
SD85_09110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SD85_09110	COG4221	oxidoreductase activity
SD85_09110	COG0300	oxidoreductase activity
SD85_09110	COG3321	synthase
SD85_09115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SD85_09115	COG3321	synthase
SD85_09115	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_09115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SD85_09115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_09120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_09120	COG3321	synthase
SD85_09120	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_09120	COG4221	oxidoreductase activity
SD85_09125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SD85_09125	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SD85_09125	COG3321	synthase
SD85_09125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SD85_09130	COG2124	cytochrome p450
SD85_09140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD85_09145	COG1404	Belongs to the peptidase S8 family
SD85_09155	COG4195	phage-related replication protein
SD85_09160	COG1764	response to oxidative stress
SD85_09185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SD85_09190	COG1923	regulation of RNA biosynthetic process
SD85_09205	COG1780	Probably involved in ribonucleotide reductase function
SD85_09210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SD85_09215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SD85_09220	COG4112	unkown
SD85_09225	COG0860	N-Acetylmuramoyl-L-alanine amidase
SD85_09235	COG0464	growth
SD85_09245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SD85_09250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SD85_09255	COG0789	Transcriptional regulator
SD85_09260	COG0174	glutamine synthetase
SD85_09275	COG2211	Major facilitator Superfamily
SD85_09280	COG3507	Belongs to the glycosyl hydrolase 43 family
SD85_09295	COG1070	Carbohydrate kinase
SD85_09310	COG2814	Major facilitator Superfamily
SD85_09315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SD85_09325	COG0756	dUTP diphosphatase activity
SD85_09375	COG3832	glyoxalase III activity
SD85_09390	COG2059	Chromate
SD85_09395	COG0697	spore germination
SD85_09420	COG4195	phage-related replication protein
SD85_09430	COG0346	lactoylglutathione lyase activity
SD85_09445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SD85_09450	COG1388	LysM domain
SD85_09455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SD85_09460	COG4224	UPF0291 protein
SD85_09465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SD85_09475	COG3763	UPF0154 protein
SD85_09485	COG0785	Cytochrome C biogenesis protein
SD85_09490	COG2201	protein-glutamate methylesterase activity
SD85_09495	COG4846	Membrane protein involved in cytochrome C biogenesis
SD85_09505	COG0071	Belongs to the small heat shock protein (HSP20) family
SD85_09520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SD85_09525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_09545	COG0824	Thioesterase
SD85_09555	COG4841	protein insertion into membrane
SD85_09560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SD85_09565	COG1832	CoA-binding protein
SD85_09570	COG0187	DNA topoisomerase II activity
SD85_09575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SD85_09590	COG1115	amino acid carrier protein
SD85_09595	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SD85_09605	COG2246	polysaccharide biosynthetic process
SD85_09610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SD85_09615	COG0586	Pfam SNARE associated Golgi protein
SD85_09635	COG2404	hydrolase activity, acting on ester bonds
SD85_09640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SD85_09645	COG1024	Enoyl-CoA hydratase
SD85_09650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SD85_09655	COG0511	ligase activity, forming carbon-carbon bonds
SD85_09660	COG0439	Biotin carboxylase
SD85_09665	COG0318	PFAM AMP-dependent synthetase and ligase
SD85_09670	COG1960	acyl-CoA dehydrogenase activity
SD85_09685	COG1649	PFAM Uncharacterised BCR, COG1649
SD85_09715	COG2027	D-alanyl-D-alanine carboxypeptidase
SD85_09720	COG2017	converts alpha-aldose to the beta-anomer
SD85_09725	COG0534	Mate efflux family protein
SD85_09750	COG5632	N-Acetylmuramoyl-L-alanine amidase
SD85_09750	COG1388	LysM domain
SD85_09750	COG3409	Peptidoglycan-binding domain 1 protein
SD85_09785	COG3942	CHAP domain
SD85_09785	COG1705	Flagellar rod assembly protein muramidase FlgJ
SD85_09900	COG0582	viral genome integration into host DNA
SD85_09995	COG0582	viral genome integration into host DNA
SD85_10000	COG0166	Belongs to the GPI family
SD85_10005	COG0405	Gamma-glutamyltransferase
SD85_10010	COG0583	DNA-binding transcription factor activity
SD85_10020	COG0493	'glutamate synthase
SD85_10025	COG0070	glutamate synthase
SD85_10025	COG0067	glutamate synthase
SD85_10025	COG0069	glutamate synthase activity
SD85_10030	COG0583	DNA-binding transcription factor activity
SD85_10035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SD85_10055	COG0300	oxidoreductase activity
SD85_10060	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
SD85_10070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD85_10095	COG2814	Major facilitator Superfamily
SD85_10100	COG1070	Carbohydrate kinase
SD85_10105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SD85_10110	COG0243	molybdopterin cofactor binding
SD85_10140	COG0840	transmembrane signaling receptor activity
SD85_10140	COG5278	phosphoserine phosphatase activity
SD85_10145	COG2368	4-hydroxyphenylacetate
SD85_10150	COG4305	rare lipoprotein A
SD85_10155	COG3619	membrane
SD85_10165	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_10180	COG2135	peptidase activity
SD85_10220	COG2720	vancomycin resistance protein
SD85_10230	COG3655	Transcriptional regulator
SD85_10235	COG3739	integral membrane protein
SD85_10240	COG0583	DNA-binding transcription factor activity
SD85_10245	COG0697	spore germination
SD85_10270	COG0693	protein deglycase activity
SD85_10275	COG2367	Beta-lactamase
SD85_10280	COG4282	regulation of fungal-type cell wall biogenesis
SD85_10285	COG3397	chitin binding
SD85_10290	COG2318	DinB family
SD85_10295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD85_10300	COG0457	Tetratricopeptide repeat
SD85_10310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SD85_10315	COG1215	transferase activity, transferring glycosyl groups
SD85_10355	COG4974	Belongs to the 'phage' integrase family
SD85_10370	COG2273	Hydrolase Family 16
SD85_10375	COG4282	regulation of fungal-type cell wall biogenesis
SD85_10380	COG1231	oxidoreductase activity
SD85_10385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD85_10390	COG0662	Cupin 2, conserved barrel domain protein
SD85_10390	COG2207	Transcriptional regulator
SD85_10395	COG0456	acetyltransferase
SD85_10405	COG1309	transcriptional regulator
SD85_10415	COG3708	Transcriptional regulator
SD85_10420	COG2378	regulation of single-species biofilm formation
SD85_10430	COG0640	Transcriptional regulator
SD85_10435	COG0741	lytic transglycosylase activity
SD85_10440	COG2322	membrane
SD85_10455	COG1619	proteins homologs of microcin C7 resistance protein MccF
SD85_10460	COG3239	Fatty acid desaturase
SD85_10465	COG4585	Histidine kinase
SD85_10470	COG2197	response regulator
SD85_10475	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SD85_10480	COG3584	3D domain protein
SD85_10480	COG1388	LysM domain
SD85_10485	COG0514	ATP-dependent DNA helicase (RecQ)
SD85_10490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SD85_10495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SD85_10510	COG1012	belongs to the aldehyde dehydrogenase family
SD85_10515	COG1657	PFAM Prenyltransferase squalene oxidase
SD85_10520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SD85_10525	COG0733	neurotransmitter:sodium symporter activity
SD85_10530	COG0385	Bile acid
SD85_10535	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD85_10540	COG0567	Dehydrogenase, E1 component
SD85_10545	COG4548	von Willebrand factor, type A
SD85_10550	COG0714	Associated with various cellular activities
SD85_10555	COG2032	superoxide dismutase activity
SD85_10560	COG1388	LysM domain
SD85_10560	COG0791	NLP P60 protein
SD85_10565	COG1819	glycosyl
SD85_10570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SD85_10575	COG0534	Mate efflux family protein
SD85_10580	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_10585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SD85_10590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SD85_10600	COG2962	Rard protein
SD85_10615	COG1942	4-Oxalocrotonate Tautomerase
SD85_10620	COG1733	regulation of RNA biosynthetic process
SD85_10625	COG0778	Nitroreductase
SD85_10630	COG0400	carboxylic ester hydrolase activity
SD85_10645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SD85_10650	COG0793	Belongs to the peptidase S41A family
SD85_10650	COG3409	Peptidoglycan-binding domain 1 protein
SD85_10655	COG2226	methyltransferase
SD85_10665	COG1876	peptidase activity
SD85_10670	COG0813	purine-nucleoside phosphorylase activity
SD85_10685	COG0671	phosphoesterase, PA-phosphatase related
SD85_10705	COG4479	Belongs to the UPF0346 family
SD85_10715	COG1509	lysine 2,3-aminomutase activity
SD85_10720	COG0456	acetyltransferase
SD85_10725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD85_10730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SD85_10735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SD85_10740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SD85_10755	COG0456	acetyltransferase
SD85_10760	COG0463	Glycosyl transferase, family 2
SD85_10775	COG4641	Protein conserved in bacteria
SD85_10780	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
SD85_10785	COG1086	Polysaccharide biosynthesis protein
SD85_10790	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SD85_10795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SD85_10800	COG1846	Transcriptional regulator
SD85_10805	COG0534	Mate efflux family protein
SD85_10815	COG4698	Protein conserved in bacteria
SD85_10820	COG2755	lipolytic protein G-D-S-L family
SD85_10825	COG1999	signal sequence binding
SD85_10840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SD85_10845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SD85_10850	COG1272	protein, Hemolysin III
SD85_10855	COG0204	Acyl-transferase
SD85_10860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SD85_10870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SD85_10880	COG2136	Putative SAM-dependent methyltransferase
SD85_10880	COG2521	methyltransferase
SD85_10890	COG0129	dihydroxy-acid dehydratase activity
SD85_10895	COG1413	lyase activity
SD85_10900	COG1418	mRNA catabolic process
SD85_10905	COG0386	Belongs to the glutathione peroxidase family
SD85_10910	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SD85_10915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SD85_10920	COG1278	Cold shock
SD85_10940	COG0328	RNA-DNA hybrid ribonuclease activity
SD85_10945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SD85_10950	COG0328	RNA-DNA hybrid ribonuclease activity
SD85_10960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SD85_10975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SD85_10980	COG1755	Isoprenylcysteine carboxyl methyltransferase
SD85_10985	COG3424	synthase
SD85_10990	COG2233	PERMEase
SD85_10995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SD85_11000	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SD85_11010	COG0800	Aldolase
SD85_11015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SD85_11020	COG1609	Transcriptional regulator
SD85_11025	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
SD85_11030	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_11035	COG1199	ATP-dependent helicase activity
SD85_11045	COG0116	Belongs to the methyltransferase superfamily
SD85_11055	COG4474	Belongs to the UPF0398 family
SD85_11070	COG3359	exonuclease
SD85_11075	COG1205	dead DEAH box helicase
SD85_11075	COG1111	helicase
SD85_11080	COG2190	(PTS) system
SD85_11085	COG0071	Belongs to the small heat shock protein (HSP20) family
SD85_11120	COG3331	DNA recombination
SD85_11125	COG4499	WXG100 protein secretion system (Wss), protein YukC
SD85_11125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SD85_11135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SD85_11140	COG3935	DnaD domain protein
SD85_11145	COG0017	Asparaginyl-tRNA synthetase
SD85_11150	COG0436	Aminotransferase
SD85_11155	COG5353	protein conserved in bacteria
SD85_11165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SD85_11165	COG1199	ATP-dependent helicase activity
SD85_11170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SD85_11175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SD85_11180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SD85_11190	COG0617	tRNA 3'-terminal CCA addition
SD85_11195	COG0438	transferase activity, transferring glycosyl groups
SD85_11200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SD85_11205	COG1803	Methylglyoxal synthase
SD85_11210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SD85_11215	COG1694	Mazg nucleotide pyrophosphohydrolase
SD85_11220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD85_11230	COG4347	Protein of unknown function (DUF1405)
SD85_11235	COG2010	Cytochrome c
SD85_11235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SD85_11240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SD85_11245	COG0723	plastoquinol--plastocyanin reductase activity
SD85_11255	COG5582	Belongs to the UPF0302 family
SD85_11260	COG0457	Tetratricopeptide repeat
SD85_11265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SD85_11270	COG0287	Prephenate dehydrogenase
SD85_11275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SD85_11280	COG0159	tryptophan synthase activity
SD85_11285	COG0133	tryptophan synthase activity
SD85_11290	COG0135	phosphoribosylanthranilate isomerase activity
SD85_11300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SD85_11305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SD85_11310	COG4401	Chorismate mutase type I
SD85_11315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SD85_11320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SD85_11325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SD85_11335	COG0105	UTP biosynthetic process
SD85_11340	COG0142	geranyltranstransferase activity
SD85_11345	COG2226	methyltransferase
SD85_11350	COG0142	geranyltranstransferase activity
SD85_11360	COG0302	gtp cyclohydrolase
SD85_11365	COG0776	regulation of translation
SD85_11370	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SD85_11385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SD85_11390	COG1160	GTP binding
SD85_11415	COG1304	FMN binding
SD85_11420	COG0539	negative regulation of cytoplasmic translation
SD85_11425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SD85_11435	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SD85_11440	COG2959	enzyme of heme biosynthesis
SD85_11445	COG3773	Cell wall hydrolase
SD85_11445	COG3409	Peptidoglycan-binding domain 1 protein
SD85_11450	COG2339	peptidase activity
SD85_11455	COG0492	ferredoxin-NADP+ reductase activity
SD85_11460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SD85_11465	COG4862	establishment of competence for transformation
SD85_11470	COG1408	metallophosphoesterase
SD85_11480	COG1388	LysM domain
SD85_11485	COG1266	CAAX protease self-immunity
SD85_11490	COG0514	ATP-dependent DNA helicase (RecQ)
SD85_11495	COG4955	Helix-turn-helix domain
SD85_11500	COG1141	Ferredoxin
SD85_11505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SD85_11515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SD85_11520	COG0710	3-dehydroquinate dehydratase activity
SD85_11530	COG1595	DNA-templated transcription, initiation
SD85_11535	COG5002	protein histidine kinase activity
SD85_11540	COG0745	RESPONSE REGULATOR receiver
SD85_11545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SD85_11550	COG1333	cytochrome c biogenesis protein
SD85_11555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_11560	COG1187	pseudouridine synthase activity
SD85_11565	COG0700	Nucleoside recognition
SD85_11570	COG2715	membrane protein required for spore maturation
SD85_11575	COG1686	Belongs to the peptidase S11 family
SD85_11585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SD85_11590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SD85_11595	COG1547	Domain of unknown function (DUF309)
SD85_11600	COG0456	acetyltransferase
SD85_11605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SD85_11610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SD85_11610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SD85_11615	COG0307	riboflavin synthase, alpha
SD85_11620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SD85_11620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SD85_11630	COG0681	Belongs to the peptidase S26 family
SD85_11635	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
SD85_11645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SD85_11655	COG4086	secreted protein
SD85_11660	COG0019	diaminopimelate decarboxylase activity
SD85_11665	COG0697	spore germination
SD85_11680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SD85_11700	COG1191	sigma factor activity
SD85_11705	COG2172	sigma factor antagonist activity
SD85_11710	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_11715	COG1686	Belongs to the peptidase S11 family
SD85_11720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SD85_11725	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SD85_11730	COG4974	Belongs to the 'phage' integrase family
SD85_11740	COG0735	belongs to the Fur family
SD85_11745	COG1300	Membrane
SD85_11755	COG0281	malic enzyme
SD85_11760	COG1757	Na H antiporter
SD85_11765	COG1027	Aspartate ammonia-lyase
SD85_11770	COG0252	asparaginase activity
SD85_11775	COG1396	sequence-specific DNA binding
SD85_11785	COG2801	Transposase and inactivated derivatives
SD85_11795	COG0494	nUDIX hydrolase
SD85_11805	COG0667	Aldo Keto reductase
SD85_11815	COG1073	alpha beta
SD85_11820	COG0772	Belongs to the SEDS family
SD85_11825	COG0772	Belongs to the SEDS family
SD85_11830	COG3339	Conserved Protein
SD85_11840	COG4918	Iron-sulphur cluster biosynthesis
SD85_11845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SD85_11845	COG0456	acetyltransferase
SD85_11850	COG2329	Antibiotic biosynthesis monooxygenase
SD85_11855	COG0456	acetyltransferase
SD85_11865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SD85_11880	COG2211	Major facilitator Superfamily
SD85_11890	COG0346	lactoylglutathione lyase activity
SD85_11895	COG1072	(Pantothenic acid kinase))
SD85_11900	COG3048	D-serine ammonia-lyase activity
SD85_11905	COG0300	oxidoreductase activity
SD85_11910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD85_11915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SD85_11920	COG4187	Peptidase family M20/M25/M40
SD85_11925	COG1902	pentaerythritol trinitrate reductase activity
SD85_11930	COG0596	Alpha beta hydrolase
SD85_11950	COG1234	tRNA 3'-trailer cleavage
SD85_11955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SD85_11960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SD85_11965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SD85_11975	COG0706	membrane insertase activity
SD85_11980	COG3361	conserved protein (COG2071)
SD85_11985	COG2195	Cleaves the N-terminal amino acid of tripeptides
SD85_11990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SD85_11995	COG0346	lactoylglutathione lyase activity
SD85_12005	COG1376	ErfK ybiS ycfS ynhG family protein
SD85_12010	COG4129	membrane
SD85_12015	COG1126	abc transporter atp-binding protein
SD85_12020	COG0765	amino acid transport
SD85_12025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SD85_12035	COG1597	lipid kinase activity
SD85_12040	COG2814	Major facilitator Superfamily
SD85_12045	COG0789	Transcriptional regulator
SD85_12045	COG4978	Transcriptional regulator
SD85_12050	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD85_12055	COG0022	dehydrogenase e1 component
SD85_12060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SD85_12065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SD85_12070	COG3426	butyrate kinase activity
SD85_12075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SD85_12080	COG0280	phosphate acetyltransferase
SD85_12085	COG3290	protein histidine kinase activity
SD85_12085	COG3829	transcription factor binding
SD85_12095	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SD85_12100	COG2079	MmgE PrpD family protein
SD85_12105	COG0372	Belongs to the citrate synthase family
SD85_12110	COG1960	acyl-CoA dehydrogenase activity
SD85_12115	COG1250	3-hydroxyacyl-CoA dehydrogenase
SD85_12120	COG0183	Belongs to the thiolase family
SD85_12125	COG0584	glycerophosphoryl diester phosphodiesterase
SD85_12130	COG0860	N-Acetylmuramoyl-L-alanine amidase
SD85_12145	COG1902	pentaerythritol trinitrate reductase activity
SD85_12155	COG0745	RESPONSE REGULATOR receiver
SD85_12165	COG0750	zinc metalloprotease
SD85_12170	COG0497	DNA recombination
SD85_12175	COG1438	arginine binding
SD85_12180	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SD85_12185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SD85_12190	COG0142	geranyltranstransferase activity
SD85_12195	COG1722	exodeoxyribonuclease VII activity
SD85_12200	COG1570	exodeoxyribonuclease VII activity
SD85_12205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SD85_12210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SD85_12215	COG1302	Protein conserved in bacteria
SD85_12220	COG0439	Biotin carboxylase
SD85_12225	COG0511	ligase activity, forming carbon-carbon bonds
SD85_12265	COG3854	ATPases associated with a variety of cellular activities
SD85_12275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SD85_12280	COG0006	proline dipeptidase activity
SD85_12285	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SD85_12295	COG3872	metal-dependent enzyme
SD85_12305	COG1752	Esterase of the alpha-beta hydrolase superfamily
SD85_12310	COG1321	iron dependent repressor
SD85_12315	COG0095	Lipoate-protein ligase
SD85_12320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SD85_12325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SD85_12330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SD85_12335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SD85_12340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SD85_12355	COG1396	sequence-specific DNA binding
SD85_12365	COG0681	Belongs to the peptidase S26 family
SD85_12390	COG4940	Competence protein ComGF
SD85_12400	COG4970	Tfp pilus assembly protein FimT
SD85_12405	COG4537	Required for transformation and DNA binding
SD85_12410	COG1459	type II secretion system
SD85_12415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SD85_12420	COG0517	IMP dehydrogenase activity
SD85_12425	COG0598	Magnesium transport protein CorA
SD85_12430	COG1253	flavin adenine dinucleotide binding
SD85_12435	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_12445	COG1393	Belongs to the ArsC family
SD85_12455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD85_12465	COG0011	TIGRFAM Protein of
SD85_12475	COG2866	Carboxypeptidase
SD85_12480	COG1368	sulfuric ester hydrolase activity
SD85_12485	COG1940	carbohydrate kinase activity
SD85_12490	COG4483	Protein conserved in bacteria
SD85_12495	COG0705	Rhomboid family
SD85_12495	COG0457	Tetratricopeptide repeat
SD85_12505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SD85_12510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SD85_12515	COG0438	transferase activity, transferring glycosyl groups
SD85_12530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SD85_12535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SD85_12540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SD85_12545	COG0581	inorganic phosphate transmembrane transporter activity
SD85_12550	COG0573	inorganic phosphate transmembrane transporter activity
SD85_12555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SD85_12565	COG0477	Major facilitator Superfamily
SD85_12570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SD85_12575	COG2839	Protein conserved in bacteria
SD85_12580	COG5521	maltodextrose utilization protein MalA
SD85_12585	COG1388	LysM domain
SD85_12590	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SD85_12595	COG4709	membrane
SD85_12600	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
SD85_12605	COG0735	belongs to the Fur family
SD85_12610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD85_12620	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SD85_12625	COG0513	Belongs to the DEAD box helicase family
SD85_12635	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SD85_12640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SD85_12645	COG2384	SAM-dependent methyltransferase
SD85_12650	COG2010	Cytochrome c
SD85_12655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SD85_12660	COG0358	DNA primase activity
SD85_12665	COG1671	Belongs to the UPF0178 family
SD85_12670	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SD85_12675	COG0517	IMP dehydrogenase activity
SD85_12680	COG0751	glycine-tRNA ligase activity
SD85_12685	COG0752	glycyl-tRNA synthetase alpha subunit
SD85_12690	COG1381	Involved in DNA repair and RecF pathway recombination
SD85_12700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SD85_12705	COG0295	cytidine deaminase activity
SD85_12710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SD85_12715	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SD85_12720	COG1480	7TM receptor with intracellular HD hydrolase
SD85_12730	COG1702	phosphate starvation-inducible protein PhoH
SD85_12735	COG0561	phosphatase activity
SD85_12750	COG4864	UPF0365 protein
SD85_12755	COG1030	water channel activity
SD85_12760	COG1610	YqeY-like protein
SD85_12765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SD85_12770	COG1283	sodium-dependent phosphate transmembrane transporter activity
SD85_12775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SD85_12780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SD85_12785	COG2264	protein methyltransferase activity
SD85_12790	COG0484	heat shock protein binding
SD85_12800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SD85_12805	COG1420	regulation of RNA biosynthetic process
SD85_12810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SD85_12815	COG0481	GTPase activity
SD85_12825	COG0860	N-Acetylmuramoyl-L-alanine amidase
SD85_12830	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SD85_12835	COG0268	Binds directly to 16S ribosomal RNA
SD85_12840	COG1466	dna polymerase III delta subunit
SD85_12850	COG0658	competence protein
SD85_12850	COG2333	competence protein COMEC
SD85_12855	COG2131	deaminase
SD85_12860	COG1596	polysaccharide export
SD85_12860	COG1555	photosystem II stabilization
SD85_12865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SD85_12870	COG2226	methyltransferase
SD85_12875	COG0799	negative regulation of ribosome biogenesis
SD85_12880	COG1713	HD superfamily hydrolase involved in NAD metabolism
SD85_12885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SD85_12890	COG1534	Rna-binding protein
SD85_12895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SD85_12900	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SD85_12905	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SD85_12920	COG2755	lipolytic protein G-D-S-L family
SD85_12930	COG3409	Peptidoglycan-binding domain 1 protein
SD85_12930	COG5632	N-Acetylmuramoyl-L-alanine amidase
SD85_12935	COG0398	Pfam SNARE associated Golgi protein
SD85_12940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SD85_12950	COG3209	COG3209 Rhs family protein
SD85_12960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SD85_12965	COG0114	fumarate hydratase activity
SD85_12970	COG0583	DNA-binding transcription factor activity
SD85_12990	COG2070	2-Nitropropane dioxygenase
SD85_12995	COG1846	Transcriptional regulator
SD85_13005	COG1733	regulation of RNA biosynthetic process
SD85_13015	COG2207	Transcriptional regulator
SD85_13025	COG4221	oxidoreductase activity
SD85_13030	COG0456	acetyltransferase
SD85_13035	COG4978	Transcriptional regulator
SD85_13035	COG0789	Transcriptional regulator
SD85_13040	COG2814	Major facilitator Superfamily
SD85_13045	COG1183	phosphatidylcholine synthase activity
SD85_13055	COG2186	Transcriptional regulator
SD85_13060	COG0205	6-phosphofructokinase activity
SD85_13070	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_13075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SD85_13080	COG3959	Transketolase, thiamine diphosphate binding domain
SD85_13095	COG0640	Transcriptional regulator
SD85_13105	COG2315	Protein conserved in bacteria
SD85_13120	COG3443	Belongs to the bacterial solute-binding protein 9 family
SD85_13125	COG4991	sh3 domain protein
SD85_13130	COG4991	sh3 domain protein
SD85_13140	COG5577	PFAM Coat F domain
SD85_13145	COG1063	alcohol dehydrogenase
SD85_13155	COG5577	PFAM Coat F domain
SD85_13165	COG0667	Aldo Keto reductase
SD85_13170	COG2207	Transcriptional regulator
SD85_13175	COG0789	Transcriptional regulator
SD85_13180	COG0789	Transcriptional regulator
SD85_13185	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SD85_13190	COG1064	alcohol dehydrogenase
SD85_13195	COG0693	protein deglycase activity
SD85_13200	COG1621	beta-fructofuranosidase activity
SD85_13205	COG3716	PTS system mannose fructose sorbose family IID component
SD85_13210	COG3715	PTS system
SD85_13215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_13220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD85_13225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SD85_13225	COG3933	PFAM sigma-54 factor interaction domain-containing protein
SD85_13240	COG1113	amino acid transport
SD85_13245	COG1280	lysine exporter protein (LysE YggA)
SD85_13250	COG1378	Sugar-specific transcriptional regulator TrmB
SD85_13255	COG1595	DNA-templated transcription, initiation
SD85_13265	COG2755	lipolytic protein G-D-S-L family
SD85_13265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SD85_13275	COG2124	cytochrome p450
SD85_13275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SD85_13280	COG1309	transcriptional regulator
SD85_13285	COG2226	methyltransferase
SD85_13305	COG2116	formate transmembrane transporter activity
SD85_13310	COG5609	conserved protein (DUF2294)
SD85_13315	COG3383	formate dehydrogenase (NAD+) activity
SD85_13320	COG2427	Protein of unknown function (DUF1641)
SD85_13330	COG0626	cystathionine gamma-synthase activity
SD85_13335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SD85_13340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SD85_13345	COG2226	methyltransferase
SD85_13360	COG0768	penicillin binding
SD85_13365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SD85_13370	COG0572	uridine kinase
SD85_13390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SD85_13395	COG3906	Belongs to the UPF0473 family
SD85_13400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SD85_13405	COG4472	Bacterial protein of unknown function (DUF965)
SD85_13410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SD85_13415	COG0628	permease
SD85_13430	COG3881	PFAM PRC-barrel domain
SD85_13435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SD85_13440	COG0457	Tetratricopeptide repeat
SD85_13445	COG0482	sulfurtransferase activity
SD85_13450	COG1104	cysteine desulfurase activity
SD85_13455	COG1959	2 iron, 2 sulfur cluster binding
SD85_13460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SD85_13475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SD85_13485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SD85_13490	COG0124	histidyl-tRNA synthetase
SD85_13505	COG0860	N-Acetylmuramoyl-L-alanine amidase
SD85_13505	COG3103	Sh3 type 3 domain protein
SD85_13505	COG4991	sh3 domain protein
SD85_13510	COG1490	D-aminoacyl-tRNA deacylase activity
SD85_13515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SD85_13520	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SD85_13525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SD85_13525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SD85_13530	COG5416	Lipopolysaccharide assembly protein A domain
SD85_13535	COG0490	domain, Protein
SD85_13540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SD85_13540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SD85_13550	COG2244	polysaccharide biosynthetic process
SD85_13555	COG2323	membrane
SD85_13565	COG1862	Preprotein translocase
SD85_13570	COG0343	queuine tRNA-ribosyltransferase activity
SD85_13575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SD85_13585	COG2255	four-way junction helicase activity
SD85_13590	COG0632	four-way junction helicase activity
SD85_13600	COG2814	Major facilitator Superfamily
SD85_13605	COG0673	inositol 2-dehydrogenase activity
SD85_13610	COG2112	serine threonine protein kinase
SD85_13620	COG1115	amino acid carrier protein
SD85_13625	COG0217	transcriptional regulatory protein
SD85_13635	COG1388	LysM domain
SD85_13640	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SD85_13645	COG0157	Belongs to the NadC ModD family
SD85_13650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SD85_13655	COG1104	cysteine desulfurase activity
SD85_13660	COG1827	regulation of RNA biosynthetic process
SD85_13665	COG0077	Prephenate dehydratase
SD85_13670	COG4492	Belongs to the UPF0735 family
SD85_13675	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SD85_13680	COG3290	protein histidine kinase activity
SD85_13690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SD85_13695	COG2868	ribosomal protein
SD85_13700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SD85_13705	COG1994	Peptidase M50
SD85_13710	COG0739	heme binding
SD85_13715	COG2894	cell division
SD85_13720	COG0850	regulation of cytokinetic process
SD85_13725	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SD85_13730	COG1792	Involved in formation and maintenance of cell shape
SD85_13735	COG1077	Cell shape determining protein MreB Mrl
SD85_13740	COG2003	Belongs to the UPF0758 family
SD85_13745	COG0424	maF-like protein
SD85_13755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SD85_13760	COG0285	dihydrofolate synthase activity
SD85_13765	COG0525	valine-tRNA ligase activity
SD85_13775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SD85_13780	COG1388	LysM domain
SD85_13785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SD85_13790	COG0113	porphobilinogen synthase activity
SD85_13795	COG1587	Uroporphyrinogen-III synthase
SD85_13800	COG0181	hydroxymethylbilane synthase activity
SD85_13805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SD85_13810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SD85_13820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SD85_13825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SD85_13830	COG0470	DNA polymerase III
SD85_13830	COG1067	ATP-dependent peptidase activity
SD85_13835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SD85_13840	COG0544	peptidyl-prolyl cis-trans isomerase activity
SD85_13845	COG1477	protein flavinylation
SD85_13845	COG0457	Tetratricopeptide repeat
SD85_13850	COG0066	3-isopropylmalate dehydratase activity
SD85_13855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SD85_13860	COG0473	3-isopropylmalate dehydrogenase activity
SD85_13865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SD85_13870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SD85_13875	COG0440	acetolactate synthase activity
SD85_13880	COG0028	Belongs to the TPP enzyme family
SD85_13890	COG0454	-acetyltransferase
SD85_13900	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
SD85_13910	COG0622	Phosphoesterase
SD85_13915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SD85_13920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SD85_13925	COG5401	PFAM Sporulation and spore germination
SD85_13930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SD85_13935	COG1846	Transcriptional regulator
SD85_13940	COG2197	response regulator
SD85_13945	COG0824	Thioesterase
SD85_13950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SD85_13955	COG1053	succinate dehydrogenase
SD85_13960	COG2009	succinate dehydrogenase
SD85_13970	COG1719	4-vinyl reductase, 4VR
SD85_13975	COG0527	aspartate kinase activity
SD85_13980	COG0322	excinuclease ABC activity
SD85_13985	COG3118	belongs to the thioredoxin family
SD85_13990	COG3534	alpha-L-arabinofuranosidase
SD85_13995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SD85_14000	COG2086	electron transfer activity
SD85_14005	COG1024	Enoyl-CoA hydratase
SD85_14010	COG1309	transcriptional regulator
SD85_14015	COG0318	PFAM AMP-dependent synthetase and ligase
SD85_14020	COG3766	membrane
SD85_14025	COG1193	negative regulation of DNA recombination
SD85_14030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SD85_14030	COG1796	DNA polymerase
SD85_14035	COG1286	toxin biosynthetic process
SD85_14040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
SD85_14045	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SD85_14050	COG0072	phenylalanine-tRNA ligase activity
SD85_14050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD85_14055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SD85_14060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SD85_14070	COG0584	glycerophosphoryl diester phosphodiesterase
SD85_14075	COG0277	FAD linked oxidase domain protein
SD85_14080	COG0247	lactate metabolic process
SD85_14085	COG0346	lactoylglutathione lyase activity
SD85_14090	COG1966	Carbon starvation protein
SD85_14105	COG1695	Transcriptional regulator
SD85_14110	COG3534	alpha-L-arabinofuranosidase
SD85_14115	COG0395	ABC-type sugar transport system, permease component
SD85_14120	COG1175	transmembrane transport
SD85_14125	COG1653	transport
SD85_14130	COG0371	Dehydrogenase
SD85_14135	COG0647	UMP catabolic process
SD85_14140	COG0235	Class ii aldolase
SD85_14145	COG1069	ribulokinase activity
SD85_14150	COG2160	L-arabinose isomerase activity
SD85_14155	COG3507	Belongs to the glycosyl hydrolase 43 family
SD85_14160	COG1363	Peptidase, m42
SD85_14170	COG3326	Membrane
SD85_14175	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SD85_14180	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SD85_14185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SD85_14200	COG1346	cytolysis
SD85_14205	COG1380	Effector of murein hydrolase LrgA
SD85_14210	COG3279	Response regulator of the LytR AlgR family
SD85_14215	COG3275	phosphorelay sensor kinase activity
SD85_14225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SD85_14235	COG0398	Pfam SNARE associated Golgi protein
SD85_14240	COG1484	DNA-dependent DNA replication
SD85_14245	COG3611	Membrane attachment protein
SD85_14250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SD85_14255	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SD85_14260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SD85_14265	COG1733	regulation of RNA biosynthetic process
SD85_14270	COG2814	Major facilitator Superfamily
SD85_14275	COG0656	L-ascorbic acid biosynthetic process
SD85_14280	COG0237	dephospho-CoA kinase activity
SD85_14295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SD85_14300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SD85_14300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SD85_14305	COG5002	protein histidine kinase activity
SD85_14310	COG0745	RESPONSE REGULATOR receiver
SD85_14315	COG0039	L-malate dehydrogenase activity
SD85_14320	COG0538	isocitrate dehydrogenase activity
SD85_14325	COG0372	Belongs to the citrate synthase family
SD85_14330	COG2707	UPF0756 membrane protein
SD85_14335	COG0628	permease
SD85_14340	COG3030	protein affecting phage T7 exclusion by the F plasmid
SD85_14345	COG0469	pyruvate kinase activity
SD85_14350	COG0205	6-phosphofructokinase activity
SD85_14355	COG0825	malonyl-CoA metabolic process
SD85_14360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SD85_14365	COG0281	malic enzyme
SD85_14370	COG0587	DNA-directed DNA polymerase activity
SD85_14390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SD85_14400	COG4109	DRTGG domain
SD85_14405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SD85_14410	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_14420	COG0165	Argininosuccinate lyase
SD85_14425	COG0137	argininosuccinate synthase activity
SD85_14430	COG0521	Mo-molybdopterin cofactor biosynthetic process
SD85_14435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SD85_14440	COG0827	DNA restriction-modification system
SD85_14445	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SD85_14450	COG3874	Sporulation protein YtfJ
SD85_14460	COG1714	RDD family
SD85_14465	COG0616	signal peptide processing
SD85_14470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SD85_14475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SD85_14480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SD85_14490	COG0301	tRNA thio-modification
SD85_14495	COG1104	cysteine desulfurase activity
SD85_14500	COG1114	Component of the transport system for branched-chain amino acids
SD85_14505	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SD85_14510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SD85_14515	COG1309	transcriptional regulator
SD85_14520	COG1956	GAF domain-containing protein
SD85_14525	COG2199	diguanylate cyclase activity
SD85_14525	COG2203	Gaf domain
SD85_14530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SD85_14540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SD85_14545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SD85_14550	COG0454	-acetyltransferase
SD85_14555	COG0517	IMP dehydrogenase activity
SD85_14560	COG0123	including yeast histone deacetylase and acetoin utilization protein
SD85_14565	COG1360	Flagellar Motor Protein
SD85_14570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SD85_14575	COG1609	Transcriptional regulator
SD85_14580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SD85_14580	COG1605	Chorismate mutase
SD85_14585	COG3118	belongs to the thioredoxin family
SD85_14590	COG4980	gas vesicle protein
SD85_14595	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
SD85_14600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SD85_14605	COG1674	ftsk spoiiie
SD85_14610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD85_14615	COG4848	Belongs to the UPF0354 family
SD85_14620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_14630	COG1363	Peptidase, m42
SD85_14635	COG5584	Small secreted protein
SD85_14640	COG0281	malic enzyme
SD85_14645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD85_14650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SD85_14660	COG0510	thiamine kinase activity
SD85_14665	COG1523	belongs to the glycosyl hydrolase 13 family
SD85_14670	COG1597	lipid kinase activity
SD85_14680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SD85_14685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SD85_14690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD85_14695	COG2252	PERMEase
SD85_14700	COG4473	ABC transporter
SD85_14705	COG1131	(ABC) transporter
SD85_14710	COG1349	DNA-binding transcription factor activity
SD85_14715	COG1187	pseudouridine synthase activity
SD85_14720	COG2244	polysaccharide biosynthetic process
SD85_14725	COG2081	HI0933 family
SD85_14730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SD85_14740	COG5578	integral membrane protein
SD85_14745	COG0673	inositol 2-dehydrogenase activity
SD85_14750	COG1653	transport
SD85_14755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SD85_14760	COG4209	transmembrane transport
SD85_14765	COG2207	Transcriptional regulator
SD85_14770	COG1653	transport
SD85_14775	COG0395	ABC-type sugar transport system, permease component
SD85_14780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SD85_14785	COG2124	cytochrome p450
SD85_14790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SD85_14800	COG0156	8-amino-7-oxononanoate synthase activity
SD85_14805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SD85_14820	COG1073	alpha beta
SD85_14845	COG1486	melibiose metabolic process
SD85_14850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SD85_14855	COG0495	leucyl-tRNA aminoacylation
SD85_14865	COG2202	Pas domain
SD85_14865	COG1366	Belongs to the anti-sigma-factor antagonist family
SD85_14870	COG2814	Major facilitator Superfamily
SD85_14875	COG2433	Pfam Transposase IS66
SD85_14880	COG0577	efflux transmembrane transporter activity
SD85_14885	COG1136	(ABC) transporter
SD85_14890	COG2205	protein histidine kinase activity
SD85_14895	COG0745	RESPONSE REGULATOR receiver
SD85_14900	COG0577	efflux transmembrane transporter activity
SD85_14905	COG1136	(ABC) transporter
SD85_14920	COG1131	(ABC) transporter
SD85_14925	COG1725	Transcriptional regulator
SD85_14940	COG1242	4 iron, 4 sulfur cluster binding
SD85_14945	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SD85_14955	COG2267	carboxylic ester hydrolase activity
SD85_14960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SD85_14965	COG1113	amino acid transport
SD85_14970	COG0367	asparagine synthase
SD85_14975	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SD85_14980	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SD85_14990	COG1506	peptidase
SD85_14995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SD85_15000	COG1116	anion transmembrane transporter activity
SD85_15005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SD85_15010	COG2801	Transposase and inactivated derivatives
SD85_15020	COG0494	nUDIX hydrolase
SD85_15025	COG4824	toxin secretion phage lysis holin
SD85_15030	COG0783	Belongs to the Dps family
SD85_15045	COG1854	S-ribosylhomocysteine lyase activity
SD85_15050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SD85_15055	COG0288	reversible hydration of carbon dioxide
SD85_15060	COG0254	rRNA binding
SD85_15065	COG1271	oxidase subunit
SD85_15070	COG1294	oxidase, subunit
SD85_15080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SD85_15085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SD85_15085	COG1321	iron dependent repressor
SD85_15090	COG1121	(ABC) transporter
SD85_15095	COG0803	Belongs to the bacterial solute-binding protein 9 family
SD85_15100	COG4948	Mandelate Racemase Muconate Lactonizing
SD85_15105	COG0318	PFAM AMP-dependent synthetase and ligase
SD85_15110	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SD85_15115	COG0596	Alpha beta hydrolase
SD85_15120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SD85_15125	COG1169	isochorismate synthase
SD85_15130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SD85_15135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SD85_15140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SD85_15145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SD85_15150	COG0438	transferase activity, transferring glycosyl groups
SD85_15160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SD85_15165	COG0438	transferase activity, transferring glycosyl groups
SD85_15170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SD85_15175	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
SD85_15180	COG0058	SHG alpha-glucan phosphorylase activity
SD85_15185	COG0297	glycogen (starch) synthase activity
SD85_15190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SD85_15195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SD85_15200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SD85_15330	COG3859	Proton-coupled thiamine transporter YuaJ
SD85_15335	COG1247	-acetyltransferase
SD85_15340	COG2268	Band 7 protein
SD85_15345	COG1585	Membrane protein implicated in regulation of membrane protease activity
SD85_15350	COG2318	DinB family
SD85_15360	COG1454	alcohol dehydrogenase
SD85_15370	COG1510	regulation of RNA biosynthetic process
SD85_15380	COG0569	domain protein
SD85_15385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SD85_15390	COG4682	membrane
SD85_15395	COG1705	Flagellar rod assembly protein muramidase FlgJ
SD85_15400	COG0477	Major facilitator Superfamily
SD85_15405	COG5553	Cysteine dioxygenase type I
SD85_15415	COG1968	undecaprenyl-diphosphatase activity
SD85_15420	COG0628	permease
SD85_15425	COG0673	inositol 2-dehydrogenase activity
SD85_15430	COG4806	L-rhamnose isomerase
SD85_15435	COG3254	rhamnose metabolic process
SD85_15440	COG1070	Carbohydrate kinase
SD85_15445	COG1349	DNA-binding transcription factor activity
SD85_15450	COG3347	Dehydrogenase
SD85_15450	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_15455	COG0840	transmembrane signaling receptor activity
SD85_15460	COG0840	transmembrane signaling receptor activity
SD85_15465	COG0840	transmembrane signaling receptor activity
SD85_15470	COG0840	transmembrane signaling receptor activity
SD85_15485	COG2070	2-Nitropropane dioxygenase
SD85_15490	COG0432	Pfam Uncharacterised protein family UPF0047
SD85_15495	COG0366	Alpha amylase catalytic
SD85_15505	COG2801	Transposase and inactivated derivatives
SD85_15510	COG1253	flavin adenine dinucleotide binding
SD85_15515	COG2738	Putative neutral zinc metallopeptidase
SD85_15530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SD85_15545	COG0166	Belongs to the GPI family
SD85_15550	COG1979	alcohol dehydrogenase
SD85_15555	COG1979	alcohol dehydrogenase
SD85_15560	COG2155	Conserved Protein
SD85_15565	COG1098	S1 RNA binding domain
SD85_15570	COG0436	Aminotransferase
SD85_15575	COG1522	sequence-specific DNA binding
SD85_15580	COG2267	carboxylic ester hydrolase activity
SD85_15590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SD85_15595	COG2205	protein histidine kinase activity
SD85_15605	COG5018	Exonuclease
SD85_15615	COG2814	Major facilitator Superfamily
SD85_15620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SD85_15625	COG3011	Protein conserved in bacteria
SD85_15635	COG3290	protein histidine kinase activity
SD85_15640	COG4565	transcriptional regulatory protein
SD85_15645	COG3493	citrate carrier protein
SD85_15655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SD85_15655	COG2111	Na H antiporter
SD85_15660	COG2111	Na H antiporter
SD85_15665	COG1006	Multisubunit Na H antiporter MnhC subunit
SD85_15670	COG0651	ATP synthesis coupled electron transport
SD85_15675	COG1863	multisubunit Na H antiporter MnhE subunit
SD85_15680	COG2212	antiporter activity
SD85_15685	COG1320	monovalent cation:proton antiporter activity
SD85_15690	COG2050	protein possibly involved in aromatic compounds catabolism
SD85_15695	COG2197	response regulator
SD85_15700	COG4585	Histidine kinase
SD85_15710	COG0142	geranyltranstransferase activity
SD85_15725	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SD85_15730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SD85_15735	COG1335	isochorismatase
SD85_15740	COG5506	Protein of unknown function (DUF1694)
SD85_15755	COG0628	permease
SD85_15770	COG1418	mRNA catabolic process
SD85_15775	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_15785	COG1511	domain protein
SD85_15790	COG1674	ftsk spoiiie
SD85_15790	COG0433	COG0433 Predicted ATPase
SD85_15795	COG4499	WXG100 protein secretion system (Wss), protein YukC
SD85_15800	COG5417	Belongs to the EsaB family
SD85_15805	COG4842	Belongs to the WXG100 family
SD85_15810	COG2508	Transcriptional regulator
SD85_15810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SD85_15815	COG0686	Belongs to the AlaDH PNT family
SD85_15820	COG5634	Uncharacterized conserved protein (DUF2278)
SD85_15825	COG3251	PFAM MbtH domain protein
SD85_15830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_15835	COG1535	isochorismatase
SD85_15835	COG3433	isochorismatase activity
SD85_15840	COG1021	2,3-dihydroxybenzoate-AMP ligase
SD85_15845	COG1169	isochorismate synthase
SD85_15850	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_15855	COG2819	hydrolase of the alpha beta superfamily
SD85_15860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SD85_15865	COG1268	BioY protein
SD85_15870	COG2056	Na+-H+ antiporter family
SD85_15875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SD85_15880	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SD85_15885	COG3584	3D domain protein
SD85_15900	COG1252	NADH dehydrogenase
SD85_15905	COG0492	ferredoxin-NADP+ reductase activity
SD85_15915	COG0516	GMP reductase activity
SD85_15930	COG1131	(ABC) transporter
SD85_15950	COG0456	acetyltransferase
SD85_15960	COG0316	Belongs to the HesB IscA family
SD85_15965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SD85_15970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SD85_15975	COG4844	belongs to the
SD85_15980	COG1252	NADH dehydrogenase
SD85_15985	COG4837	Protein of unknown function (DUF1462)
SD85_15990	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SD85_15995	COG1506	peptidase
SD85_15995	COG4946	Tricorn protease homolog
SD85_15995	COG0823	Involved in the tonB-independent uptake of proteins
SD85_16000	COG0083	homoserine kinase activity
SD85_16005	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SD85_16010	COG0460	homoserine dehydrogenase
SD85_16015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SD85_16020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SD85_16025	COG0647	UMP catabolic process
SD85_16030	COG2445	Protein of unknown function DUF86
SD85_16035	COG4470	Protein conserved in bacteria
SD85_16045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SD85_16050	COG0739	heme binding
SD85_16060	COG3377	Domain of unknown function (DUF1805)
SD85_16065	COG0737	Belongs to the 5'-nucleotidase family
SD85_16070	COG0730	response to heat
SD85_16075	COG1801	Protein of unknown function DUF72
SD85_16085	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SD85_16090	COG2508	Transcriptional regulator
SD85_16095	COG2233	PERMEase
SD85_16100	COG2233	PERMEase
SD85_16105	COG3195	allantoin biosynthetic process
SD85_16105	COG3648	Uricase
SD85_16110	COG2351	hydroxyisourate hydrolase activity
SD85_16125	COG2080	2 iron, 2 sulfur cluster binding
SD85_16130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SD85_16135	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SD85_16140	COG2068	MobA-Related Protein
SD85_16145	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SD85_16150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SD85_16155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD85_16170	COG2356	endonuclease I
SD85_16175	COG3842	ATPase activity
SD85_16180	COG2188	Transcriptional regulator
SD85_16185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SD85_16190	COG0395	ABC-type sugar transport system, permease component
SD85_16195	COG1175	transmembrane transport
SD85_16200	COG1653	transport
SD85_16205	COG2222	sugar isomerase
SD85_16210	COG0322	excinuclease ABC activity
SD85_16215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SD85_16230	COG0346	lactoylglutathione lyase activity
SD85_16235	COG0640	Transcriptional regulator
SD85_16240	COG0719	Fe-S assembly protein
SD85_16245	COG0822	iron-sulfur transferase activity
SD85_16250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SD85_16255	COG0719	Fe-S assembly protein
SD85_16260	COG0396	ATPase activity
SD85_16270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SD85_16275	COG1464	Belongs to the NlpA lipoprotein family
SD85_16280	COG2011	ABC-type metal ion transport system permease component
SD85_16285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SD85_16295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD85_16300	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SD85_16310	COG0509	glycine decarboxylation via glycine cleavage system
SD85_16315	COG1393	Belongs to the ArsC family
SD85_16320	COG1960	acyl-CoA dehydrogenase activity
SD85_16325	COG0183	Belongs to the thiolase family
SD85_16330	COG1250	3-hydroxyacyl-CoA dehydrogenase
SD85_16330	COG1024	Enoyl-CoA hydratase
SD85_16340	COG0506	proline dehydrogenase activity
SD85_16350	COG5577	PFAM Coat F domain
SD85_16355	COG1846	Transcriptional regulator
SD85_16360	COG0477	Major facilitator Superfamily
SD85_16365	COG1942	4-Oxalocrotonate Tautomerase
SD85_16370	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_16375	COG0583	DNA-binding transcription factor activity
SD85_16385	COG1120	ATPase activity
SD85_16400	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_16405	COG0783	Belongs to the Dps family
SD85_16410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SD85_16415	COG0745	RESPONSE REGULATOR receiver
SD85_16420	COG2205	protein histidine kinase activity
SD85_16420	COG2770	Histidine kinase
SD85_16430	COG1309	transcriptional regulator
SD85_16435	COG0114	fumarate hydratase activity
SD85_16445	COG0697	spore germination
SD85_16450	COG0814	amino acid
SD85_16460	COG2197	response regulator
SD85_16465	COG4585	Histidine kinase
SD85_16470	COG4758	membrane
SD85_16475	COG3595	metallopeptidase activity
SD85_16480	COG1842	Phage shock protein A
SD85_16485	COG4758	membrane
SD85_16490	COG2814	Major facilitator Superfamily
SD85_16495	COG2096	Adenosyltransferase
SD85_16500	COG1120	ATPase activity
SD85_16505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_16510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD85_16520	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_16525	COG3386	PFAM SMP-30 Gluconolaconase
SD85_16530	COG2205	protein histidine kinase activity
SD85_16535	COG0745	RESPONSE REGULATOR receiver
SD85_16545	COG1191	sigma factor activity
SD85_16555	COG2140	Oxalate decarboxylase
SD85_16565	COG0577	efflux transmembrane transporter activity
SD85_16570	COG1136	(ABC) transporter
SD85_16575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SD85_16580	COG1120	ATPase activity
SD85_16585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD85_16595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD85_16610	COG0531	amino acid
SD85_16620	COG1988	membrane-bound metal-dependent
SD85_16625	COG1368	sulfuric ester hydrolase activity
SD85_16630	COG1910	domain protein
SD85_16635	COG0725	ABC transporter, periplasmic molybdate-binding protein
SD85_16640	COG4149	molybdate abc transporter
SD85_16645	COG0656	L-ascorbic acid biosynthetic process
SD85_16655	COG0025	NhaP-type Na H and K H
SD85_16660	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SD85_16665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SD85_16670	COG3973	AAA domain
SD85_16675	COG2860	membrane
SD85_16680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SD85_16685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SD85_16690	COG2217	Heavy metal translocating P-type atpase
SD85_16695	COG2217	Heavy metal translocating P-type atpase
SD85_16700	COG2608	mercury ion transmembrane transporter activity
SD85_16705	COG1937	Protein conserved in bacteria
SD85_16710	COG0673	inositol 2-dehydrogenase activity
SD85_16715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SD85_16720	COG1289	transmembrane transporter activity
SD85_16725	COG1802	Transcriptional regulator
SD85_16730	COG0697	spore germination
SD85_16735	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_16760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SD85_16765	COG0557	exoribonuclease II activity
SD85_16770	COG1647	Serine aminopeptidase, S33
SD85_16775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SD85_16780	COG0596	Alpha beta hydrolase
SD85_16785	COG1476	TRANSCRIPTIONal
SD85_16790	COG1396	sequence-specific DNA binding
SD85_16795	COG1396	sequence-specific DNA binding
SD85_16800	COG1733	regulation of RNA biosynthetic process
SD85_16855	COG1174	glycine betaine transport
SD85_16860	COG1732	Glycine betaine
SD85_16865	COG1174	glycine betaine transport
SD85_16870	COG0517	IMP dehydrogenase activity
SD85_16870	COG1125	glycine betaine transport
SD85_16875	COG1510	regulation of RNA biosynthetic process
SD85_16880	COG2801	Transposase and inactivated derivatives
SD85_16890	COG1174	glycine betaine transport
SD85_16895	COG1732	Glycine betaine
SD85_16900	COG1174	glycine betaine transport
SD85_16905	COG1125	glycine betaine transport
SD85_16905	COG0517	IMP dehydrogenase activity
SD85_16910	COG1510	regulation of RNA biosynthetic process
SD85_16920	COG3064	Membrane
SD85_16925	COG4640	response to antibiotic
SD85_16930	COG0456	acetyltransferase
SD85_16940	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SD85_16945	COG0149	triose-phosphate isomerase activity
SD85_16950	COG0126	phosphoglycerate kinase activity
SD85_16960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SD85_16965	COG2390	Transcriptional regulator
SD85_16970	COG2814	Major facilitator Superfamily
SD85_16975	COG1609	Transcriptional regulator
SD85_16980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SD85_16985	COG0697	spore germination
SD85_16990	COG1113	amino acid transport
SD85_16995	COG3858	chitin binding
SD85_17000	COG1556	Lactate utilization protein
SD85_17005	COG1139	Iron-sulfur cluster binding protein
SD85_17010	COG0247	lactate metabolic process
SD85_17025	COG2197	response regulator
SD85_17030	COG4585	Histidine kinase
SD85_17035	COG0842	Transport permease protein
SD85_17040	COG1131	(ABC) transporter
SD85_17045	COG0596	Alpha beta hydrolase
SD85_17050	COG2208	phosphoserine phosphatase activity
SD85_17060	COG1874	Beta-galactosidase
SD85_17065	COG3833	ABC-type maltose transport systems, permease component
SD85_17070	COG1175	transmembrane transport
SD85_17075	COG2182	Extracellular solute-binding protein
SD85_17080	COG1609	Transcriptional regulator
SD85_17085	COG2186	Transcriptional regulator
SD85_17090	COG1620	l-lactate permease
SD85_17095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SD85_17105	COG5039	Polysaccharide pyruvyl transferase
SD85_17110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SD85_17115	COG0110	maltose O-acetyltransferase activity
SD85_17120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SD85_17125	COG2244	polysaccharide biosynthetic process
SD85_17130	COG1216	Glycosyl transferase, family 2
SD85_17135	COG5039	Polysaccharide pyruvyl transferase
SD85_17140	COG1216	Glycosyl transferase, family 2
SD85_17150	COG0438	transferase activity, transferring glycosyl groups
SD85_17155	COG1215	transferase activity, transferring glycosyl groups
SD85_17160	COG0438	transferase activity, transferring glycosyl groups
SD85_17165	COG1086	Polysaccharide biosynthesis protein
SD85_17170	COG0489	protein tyrosine kinase activity
SD85_17175	COG3944	biosynthesis protein
SD85_17180	COG1396	sequence-specific DNA binding
SD85_17185	COG2272	Belongs to the type-B carboxylesterase lipase family
SD85_17195	COG3479	Phenolic acid decarboxylase
SD85_17205	COG1794	racemase activity, acting on amino acids and derivatives
SD85_17210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SD85_17215	COG1621	beta-fructofuranosidase activity
SD85_17220	COG1621	beta-fructofuranosidase activity
SD85_17225	COG0531	amino acid
SD85_17230	COG1309	transcriptional regulator
SD85_17235	COG2076	Multidrug Resistance protein
SD85_17240	COG2076	Multidrug Resistance protein
SD85_17260	COG1611	Belongs to the LOG family
SD85_17265	COG1694	Mazg nucleotide pyrophosphohydrolase
SD85_17270	COG0659	secondary active sulfate transmembrane transporter activity
SD85_17275	COG0288	reversible hydration of carbon dioxide
SD85_17280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SD85_17285	COG0577	efflux transmembrane transporter activity
SD85_17290	COG1136	(ABC) transporter
SD85_17295	COG5002	protein histidine kinase activity
SD85_17300	COG0745	RESPONSE REGULATOR receiver
SD85_17310	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SD85_17315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD85_17320	COG1481	regulation of sporulation
SD85_17325	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SD85_17330	COG1660	Displays ATPase and GTPase activities
SD85_17335	COG1051	belongs to the nudix hydrolase family
SD85_17340	COG0492	ferredoxin-NADP+ reductase activity
SD85_17345	COG3883	PFAM NLP P60 protein
SD85_17345	COG0791	NLP P60 protein
SD85_17350	COG0457	Tetratricopeptide repeat
SD85_17355	COG1132	(ABC) transporter
SD85_17375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SD85_17375	COG0140	phosphoribosyl-ATP diphosphatase activity
SD85_17380	COG0107	imidazoleglycerol-phosphate synthase activity
SD85_17385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SD85_17390	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SD85_17395	COG0131	Imidazoleglycerol-phosphate dehydratase
SD85_17400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SD85_17405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SD85_17410	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SD85_17415	COG4990	cell redox homeostasis
SD85_17420	COG5297	Belongs to the glycosyl hydrolase family 6
SD85_17425	COG0110	maltose O-acetyltransferase activity
SD85_17430	COG0546	phosphoglycolate phosphatase activity
SD85_17435	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SD85_17440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SD85_17445	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SD85_17450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SD85_17455	COG0363	glucosamine-6-phosphate deaminase activity
SD85_17465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SD85_17470	COG1846	Transcriptional regulator
SD85_17475	COG2124	cytochrome p450
SD85_17485	COG1846	Transcriptional regulator
SD85_17490	COG2814	Major facilitator Superfamily
SD85_17495	COG1950	PFAM Membrane protein of
SD85_17500	COG1983	PspC domain protein
SD85_17505	COG3595	metallopeptidase activity
SD85_17520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SD85_17530	COG4897	Protein conserved in bacteria
SD85_17535	COG0574	Belongs to the PEP-utilizing enzyme family
SD85_17535	COG3848	Pyruvate phosphate dikinase
SD85_17540	COG1309	transcriptional regulator
SD85_17545	COG2814	Major facilitator Superfamily
SD85_17550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SD85_17560	COG0793	Belongs to the peptidase S41A family
SD85_17560	COG3409	Peptidoglycan-binding domain 1 protein
SD85_17565	COG2177	Part of the ABC transporter FtsEX involved in
SD85_17570	COG2884	Cell division ATP-binding protein ftsE
SD85_17575	COG2010	Cytochrome c
SD85_17580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD85_17585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SD85_17590	COG0653	protein targeting
SD85_17595	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SD85_17610	COG1516	flagellar protein fliS
SD85_17615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SD85_17620	COG1334	flagellar protein FlaG
SD85_17625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SD85_17630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SD85_17635	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
SD85_17645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SD85_17650	COG4786	Flagellar basal body rod
SD85_17650	COG1256	bacterial-type flagellum assembly
SD85_17655	COG3418	PFAM FlgN family protein
SD85_17660	COG2747	anti-sigma28 factor FlgM
SD85_17670	COG1040	competence protein
SD85_17680	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SD85_17685	COG1307	EDD domain protein, DegV family
SD85_17690	COG2197	response regulator
SD85_17695	COG4585	Histidine kinase
SD85_17700	COG1739	Uncharacterized protein family UPF0029
SD85_17705	COG1316	TRANSCRIPTIONal
SD85_17710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SD85_17715	COG0438	transferase activity, transferring glycosyl groups
SD85_17720	COG1215	transferase activity, transferring glycosyl groups
SD85_17725	COG3206	protein involved in exopolysaccharide biosynthesis
SD85_17730	COG3307	-O-antigen
SD85_17735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SD85_17740	COG0438	transferase activity, transferring glycosyl groups
SD85_17740	COG0297	glycogen (starch) synthase activity
SD85_17745	COG2244	polysaccharide biosynthetic process
SD85_17760	COG0860	N-Acetylmuramoyl-L-alanine amidase
SD85_17760	COG2247	cell wall binding repeat
SD85_17765	COG2247	cell wall binding repeat
SD85_17765	COG2385	sporulation resulting in formation of a cellular spore
SD85_17775	COG1316	TRANSCRIPTIONal
SD85_17780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SD85_17800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SD85_17805	COG1134	teichoic acid transport
SD85_17810	COG1682	transport, permease protein
SD85_17825	COG1215	transferase activity, transferring glycosyl groups
SD85_17825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SD85_17830	COG0463	Glycosyl transferase, family 2
SD85_17875	COG4193	domain, Protein
SD85_17880	COG1482	cell wall glycoprotein biosynthetic process
SD85_17890	COG0697	spore germination
SD85_17895	COG0814	amino acid
SD85_17905	COG2814	Major facilitator Superfamily
SD85_17910	COG1316	TRANSCRIPTIONal
SD85_17915	COG0561	phosphatase activity
SD85_17920	COG0791	NLP P60 protein
SD85_17930	COG2843	Capsule synthesis protein
SD85_17940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SD85_17945	COG1609	Transcriptional regulator
SD85_17950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SD85_17955	COG1869	D-ribose catabolic process
SD85_17960	COG1129	ABC transporter
SD85_17965	COG1172	Belongs to the binding-protein-dependent transport system permease family
SD85_17970	COG1879	ABC-type sugar transport system periplasmic component
SD85_17975	COG3103	Sh3 type 3 domain protein
SD85_17985	COG2249	NAD(P)H dehydrogenase (quinone) activity
SD85_17990	COG3527	Alpha-acetolactate decarboxylase
SD85_17995	COG0028	Belongs to the TPP enzyme family
SD85_18000	COG0583	DNA-binding transcription factor activity
SD85_18005	COG5337	Spore coat protein CotH
SD85_18015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SD85_18025	COG0405	Gamma-glutamyltransferase
SD85_18030	COG1522	sequence-specific DNA binding
SD85_18035	COG2059	Chromate
SD85_18040	COG2059	Chromate
SD85_18050	COG0655	NAD(P)H dehydrogenase (quinone) activity
SD85_18055	COG0583	DNA-binding transcription factor activity
SD85_18065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD85_18065	COG2207	Transcriptional regulator
SD85_18095	COG5444	nuclease activity
SD85_18110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SD85_18115	COG4464	protein tyrosine phosphatase activity
SD85_18120	COG0489	protein tyrosine kinase activity
SD85_18125	COG3944	biosynthesis protein
SD85_18135	COG4715	Zinc finger, swim domain protein
SD85_18140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SD85_18145	COG0561	phosphatase activity
SD85_18150	COG1349	DNA-binding transcription factor activity
SD85_18155	COG0629	single-stranded DNA binding
SD85_18170	COG3764	Sortase (surface protein transpeptidase)
SD85_18180	COG3279	Response regulator of the LytR AlgR family
SD85_18185	COG0745	RESPONSE REGULATOR receiver
SD85_18185	COG2972	Histidine kinase
SD85_18190	COG1970	mechanosensitive ion channel activity
SD85_18195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SD85_18200	COG0457	Tetratricopeptide repeat
SD85_18205	COG4786	Flagellar basal body rod
SD85_18210	COG4786	Flagellar basal body rod
SD85_18215	COG1077	Cell shape determining protein MreB Mrl
SD85_18220	COG1609	Transcriptional regulator
SD85_18225	COG1846	Transcriptional regulator
SD85_18230	COG2814	Major facilitator Superfamily
SD85_18235	COG3420	alginic acid biosynthetic process
SD85_18240	COG1953	Uracil, thiamine, allantoin
SD85_18245	COG0477	Major facilitator Superfamily
SD85_18250	COG1335	isochorismatase
SD85_18260	COG0004	ammonium transporteR
SD85_18265	COG0347	Belongs to the P(II) protein family
SD85_18270	COG0671	phosphoesterase, PA-phosphatase related
SD85_18280	COG0739	heme binding
SD85_18285	COG1247	-acetyltransferase
SD85_18295	COG2089	acid synthase
SD85_18305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SD85_18310	COG0789	Transcriptional regulator
SD85_18320	COG2910	NAD(P)H-binding
SD85_18325	COG1959	2 iron, 2 sulfur cluster binding
SD85_18330	COG0804	urea catabolic process
SD85_18335	COG0832	Belongs to the urease beta subunit family
SD85_18340	COG0831	urea catabolic process
SD85_18360	COG0559	Belongs to the binding-protein-dependent transport system permease family
SD85_18370	COG3237	CsbD-like
SD85_18375	COG1994	Peptidase M50
SD85_18380	COG0457	Tetratricopeptide repeat
SD85_18385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SD85_18390	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SD85_18400	COG2304	oxidoreductase activity
SD85_18410	COG2304	oxidoreductase activity
SD85_18415	COG2385	sporulation resulting in formation of a cellular spore
SD85_18420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SD85_18430	COG4836	Membrane
SD85_18445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SD85_18450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SD85_18455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SD85_18460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SD85_18465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SD85_18475	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SD85_18480	COG0356	it plays a direct role in the translocation of protons across the membrane
SD85_18490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SD85_18495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SD85_18500	COG4475	Protein of unknown function (DUF436)
SD85_18505	COG0698	ribose 5-phosphate isomerase
SD85_18510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SD85_18515	COG1971	Probably functions as a manganese efflux pump
SD85_18520	COG0009	L-threonylcarbamoyladenylate synthase
SD85_18525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SD85_18545	COG2890	protein-(glutamine-N5) methyltransferase activity
SD85_18550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SD85_18555	COG0346	lactoylglutathione lyase activity
SD85_18560	COG0789	Transcriptional regulator
SD85_18565	COG0679	Auxin Efflux Carrier
SD85_18570	COG0281	malic enzyme
SD85_18575	COG1435	thymidine kinase activity
SD85_18580	COG0254	rRNA binding
SD85_18585	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SD85_18595	COG1494	fructose-1,6-bisphosphatase
SD85_18600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SD85_18605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SD85_18610	COG0191	fructose-bisphosphate aldolase activity
SD85_18615	COG2204	response regulator
SD85_18620	COG4821	SIS domain
SD85_18625	COG0504	CTP synthase activity
SD85_18630	COG3343	RNA polymerase activity
SD85_18635	COG1960	acyl-CoA dehydrogenase activity
SD85_18640	COG0247	lactate metabolic process
SD85_18640	COG2181	nitrate reductase activity
SD85_18645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SD85_18650	COG4294	response to UV
SD85_18660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SD85_18665	COG1132	(ABC) transporter
SD85_18670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SD85_18680	COG2181	nitrate reductase activity
SD85_18685	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SD85_18690	COG1140	nitrate reductase beta subunit
SD85_18695	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SD85_18700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SD85_18710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SD85_18715	COG2223	nitrite transmembrane transporter activity
SD85_18720	COG0018	arginyl-trna synthetase
SD85_18725	COG4506	Protein conserved in bacteria
SD85_18735	COG0535	radical SAM domain protein
SD85_18745	COG1131	(ABC) transporter
SD85_18770	COG3391	amine dehydrogenase activity
SD85_18780	COG0457	Tetratricopeptide repeat
SD85_18790	COG0010	Belongs to the arginase family
SD85_18795	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SD85_18800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SD85_18810	COG1994	Peptidase M50
SD85_18815	COG1942	4-Oxalocrotonate Tautomerase
SD85_18820	COG1846	Transcriptional regulator
SD85_18825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SD85_18835	COG3465	dGTPase activity
SD85_18840	COG1078	dGTPase activity
SD85_18845	COG4844	belongs to the
SD85_18855	COG0697	spore germination
SD85_18860	COG0095	Lipoate-protein ligase
SD85_18865	COG0583	DNA-binding transcription factor activity
SD85_18870	COG0280	phosphate acetyltransferase
SD85_18880	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_18885	COG0436	Aminotransferase
SD85_18890	COG2814	Major facilitator Superfamily
SD85_18895	COG0151	Belongs to the GarS family
SD85_18900	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_18905	COG1917	Cupin 2, conserved barrel domain protein
SD85_18910	COG0077	Prephenate dehydratase
SD85_18915	COG2814	Major facilitator Superfamily
SD85_18920	COG0833	amino acid
SD85_18925	COG4187	Peptidase family M20/M25/M40
SD85_18930	COG1012	belongs to the aldehyde dehydrogenase family
SD85_18935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SD85_18945	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SD85_18950	COG1091	dTDP-4-dehydrorhamnose reductase activity
SD85_18955	COG1088	dTDP-glucose 4,6-dehydratase activity
SD85_18960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SD85_18965	COG3980	spore coat polysaccharide biosynthesis protein
SD85_18970	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
SD85_18975	COG2089	acid synthase
SD85_18980	COG0456	acetyltransferase
SD85_18985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SD85_18990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SD85_18995	COG0463	Glycosyl transferase, family 2
SD85_19010	COG2363	Small membrane protein
SD85_19015	COG2233	PERMEase
SD85_19025	COG1012	belongs to the aldehyde dehydrogenase family
SD85_19030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SD85_19035	COG1216	Glycosyl transferase, family 2
SD85_19050	COG1695	Transcriptional regulator
SD85_19055	COG0351	phosphomethylpyrimidine kinase
SD85_19065	COG1621	beta-fructofuranosidase activity
SD85_19070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_19070	COG1263	PTS System
SD85_19075	COG2116	formate transmembrane transporter activity
SD85_19080	COG3711	transcriptional antiterminator
SD85_19090	COG1404	Belongs to the peptidase S8 family
SD85_19095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SD85_19100	COG0778	Nitroreductase
SD85_19105	COG0772	Belongs to the SEDS family
SD85_19150	COG2261	transglycosylase associated protein
SD85_19155	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SD85_19160	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SD85_19165	COG2246	polysaccharide biosynthetic process
SD85_19170	COG1309	transcriptional regulator
SD85_19180	COG3162	membrane
SD85_19185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SD85_19190	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SD85_19195	COG2837	iron assimilation
SD85_19200	COG2822	iron ion transport
SD85_19205	COG0352	thiamine-phosphate diphosphorylase activity
SD85_19210	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SD85_19215	COG0583	DNA-binding transcription factor activity
SD85_19220	COG1380	Effector of murein hydrolase LrgA
SD85_19225	COG1346	cytolysis
SD85_19230	COG1131	(ABC) transporter
SD85_19255	COG1346	cytolysis
SD85_19260	COG2814	Major facilitator Superfamily
SD85_19265	COG4895	conserved protein (DUF2196)
SD85_19270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SD85_19275	COG0346	lactoylglutathione lyase activity
SD85_19285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SD85_19290	COG1404	Belongs to the peptidase S8 family
SD85_19295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_19295	COG1263	PTS System
SD85_19300	COG3711	transcriptional antiterminator
SD85_19305	COG1442	glycosyl transferase family 8
SD85_19310	COG5522	Integral membrane protein (intg_mem_TP0381)
SD85_19315	COG1846	Transcriptional regulator
SD85_19320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SD85_19325	COG2234	aminopeptidase activity
SD85_19330	COG2357	RelA SpoT domain protein
SD85_19340	COG1575	Belongs to the MenA family. Type 1 subfamily
SD85_19355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD85_19360	COG1696	Membrane protein involved in D-alanine export
SD85_19365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SD85_19370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SD85_19375	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SD85_19380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SD85_19385	COG1486	melibiose metabolic process
SD85_19390	COG1447	Phosphotransferase system cellobiose-specific component IIA
SD85_19395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SD85_19400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SD85_19405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD85_19405	COG3711	transcriptional antiterminator
SD85_19410	COG2094	Belongs to the DNA glycosylase MPG family
SD85_19415	COG0753	catalase activity
SD85_19420	COG2814	Major facilitator Superfamily
SD85_19425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
SD85_19430	COG1131	(ABC) transporter
SD85_19450	COG1595	DNA-templated transcription, initiation
SD85_19455	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SD85_19460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SD85_19465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SD85_19470	COG4988	ABC transporter
SD85_19475	COG1294	oxidase, subunit
SD85_19480	COG1271	oxidase subunit
SD85_19485	COG3493	citrate carrier protein
SD85_19490	COG0501	Belongs to the peptidase M48B family
SD85_19500	COG0726	polysaccharide deacetylase
SD85_19515	COG3842	ATPase activity
SD85_19520	COG2508	Transcriptional regulator
SD85_19525	COG1012	belongs to the aldehyde dehydrogenase family
SD85_19530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD85_19540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SD85_19550	COG2195	Cleaves the N-terminal amino acid of tripeptides
SD85_19565	COG4894	glucomannan catabolic process
SD85_19570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SD85_19575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SD85_19580	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_19585	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SD85_19590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SD85_19595	COG2610	gluconate transmembrane transporter activity
SD85_19605	COG0500	methyltransferase
SD85_19610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SD85_19625	COG0753	catalase activity
SD85_19625	COG0693	protein deglycase activity
SD85_19630	COG2851	Citrate transporter
SD85_19635	COG2323	membrane
SD85_19645	COG2723	6-phospho-beta-galactosidase activity
SD85_19650	COG2190	(PTS) system
SD85_19650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_19650	COG1263	PTS System
SD85_19655	COG3711	transcriptional antiterminator
SD85_19665	COG2270	Major facilitator Superfamily
SD85_19670	COG0513	Belongs to the DEAD box helicase family
SD85_19675	COG3401	FG-GAP repeat protein
SD85_19675	COG2755	lipolytic protein G-D-S-L family
SD85_19785	COG0697	spore germination
SD85_19795	COG0861	Integral membrane protein TerC family
SD85_19800	COG0589	response to stress
SD85_19805	COG2723	6-phospho-beta-galactosidase activity
SD85_19810	COG2190	(PTS) system
SD85_19810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD85_19810	COG1263	PTS System
SD85_19845	COG5444	nuclease activity
SD85_19860	COG3507	Belongs to the glycosyl hydrolase 43 family
SD85_19865	COG0673	inositol 2-dehydrogenase activity
SD85_19875	COG2986	histidine ammonia-lyase
SD85_19880	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SD85_19885	COG1228	amidohydrolase
SD85_19890	COG0010	Belongs to the arginase family
SD85_19895	COG0833	amino acid
SD85_19900	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SD85_19905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SD85_19910	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SD85_19915	COG2390	Transcriptional regulator
SD85_19925	COG3192	ethanolamine utilization protein
SD85_19930	COG2079	MmgE PrpD family protein
SD85_19940	COG1126	abc transporter atp-binding protein
SD85_19945	COG0765	amino acid transport
SD85_19950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SD85_19970	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SD85_19975	COG0561	phosphatase activity
SD85_20005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD85_20010	COG5294	Protein conserved in bacteria
SD85_20015	COG0577	efflux transmembrane transporter activity
SD85_20020	COG1136	(ABC) transporter
SD85_20025	COG2205	protein histidine kinase activity
SD85_20030	COG0745	RESPONSE REGULATOR receiver
SD85_20035	COG0191	fructose-bisphosphate aldolase activity
SD85_20040	COG1082	Xylose isomerase domain protein TIM barrel
SD85_20045	COG1082	Xylose isomerase domain protein TIM barrel
SD85_20050	COG0673	inositol 2-dehydrogenase activity
SD85_20055	COG2814	Major facilitator Superfamily
SD85_20060	COG1082	Xylose isomerase domain protein TIM barrel
SD85_20065	COG3962	Belongs to the TPP enzyme family
SD85_20070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SD85_20080	COG1012	belongs to the aldehyde dehydrogenase family
SD85_20085	COG1349	DNA-binding transcription factor activity
SD85_20090	COG0667	Aldo Keto reductase
SD85_20105	COG2814	Major facilitator Superfamily
SD85_20110	COG0326	Molecular chaperone. Has ATPase activity
SD85_20120	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_20125	COG1309	transcriptional regulator
SD85_20130	COG1012	belongs to the aldehyde dehydrogenase family
SD85_20140	COG1714	RDD family
SD85_20145	COG2311	Membrane
SD85_20150	COG1917	Cupin 2, conserved barrel domain protein
SD85_20155	COG1309	transcriptional regulator
SD85_20160	COG1028	Short-chain dehydrogenase reductase Sdr
SD85_20165	COG1846	Transcriptional regulator
SD85_20170	COG1380	Effector of murein hydrolase LrgA
SD85_20175	COG1346	cytolysis
SD85_20185	COG5039	Polysaccharide pyruvyl transferase
SD85_20190	COG1929	Belongs to the glycerate kinase type-1 family
SD85_20195	COG1802	Transcriptional regulator
SD85_20200	COG1070	Carbohydrate kinase
SD85_20205	COG2610	gluconate transmembrane transporter activity
SD85_20210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SD85_20215	COG0450	alkyl hydroperoxide reductase
SD85_20220	COG3634	alkyl hydroperoxide reductase activity
SD85_20230	COG2723	6-phospho-beta-galactosidase activity
SD85_20240	COG2188	Transcriptional regulator
SD85_20250	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SD85_20255	COG0270	DNA (cytosine-5-)-methyltransferase activity
SD85_20280	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SD85_20305	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
SD85_20310	COG0456	acetyltransferase
SD85_20315	COG0457	Tetratricopeptide repeat
SD85_20325	COG0010	Belongs to the arginase family
SD85_20330	COG0833	amino acid
SD85_20335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SD85_20340	COG3829	transcription factor binding
SD85_20350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SD85_20355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SD85_20360	COG4853	Protein conserved in bacteria
SD85_20365	COG4863	YycH protein
SD85_20370	COG5002	protein histidine kinase activity
SD85_20375	COG0745	RESPONSE REGULATOR receiver
SD85_20405	COG0346	lactoylglutathione lyase activity
SD85_20410	COG0305	Participates in initiation and elongation during chromosome replication
SD85_20430	COG3093	addiction module antidote protein HigA
SD85_20435	COG2807	transmembrane transport
SD85_20440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SD85_20445	COG0359	binds to the 23S rRNA
SD85_20450	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SD85_20455	COG4241	membrane
SD85_20465	COG5577	PFAM Coat F domain
SD85_20470	COG1733	regulation of RNA biosynthetic process
SD85_20475	COG1227	inorganic diphosphatase activity
SD85_20490	COG2271	Major facilitator Superfamily
SD85_20505	COG2814	Major facilitator Superfamily
SD85_20510	COG0583	DNA-binding transcription factor activity
SD85_20515	COG2153	protein acetylation
SD85_20525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD85_20530	COG1733	regulation of RNA biosynthetic process
SD85_20540	COG1846	Transcriptional regulator
SD85_20545	COG2153	protein acetylation
SD85_20550	COG2364	Membrane
SD85_20555	COG1331	Highly conserved protein containing a thioredoxin domain
SD85_20560	COG1266	CAAX protease self-immunity
SD85_20565	COG2814	Major facilitator Superfamily
SD85_20565	COG0477	Major facilitator Superfamily
SD85_20570	COG0110	maltose O-acetyltransferase activity
SD85_20575	COG0346	lactoylglutathione lyase activity
SD85_20580	COG1609	Transcriptional regulator
SD85_20585	COG0708	Exodeoxyribonuclease III
SD85_20590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SD85_20595	COG0629	single-stranded DNA binding
SD85_20600	COG0360	Binds together with S18 to 16S ribosomal RNA
SD85_20605	COG0012	GTP binding
SD85_20610	COG0243	molybdopterin cofactor binding
SD85_20615	COG4481	Protein conserved in bacteria
SD85_20620	COG3949	Membrane
SD85_20630	COG1475	DNA binding
SD85_20635	COG1192	Involved in chromosome partitioning
SD85_20645	COG1475	DNA binding
SD85_20650	COG0357	Ribosomal RNA small subunit methyltransferase G
SD85_20655	COG0445	tRNA wobble uridine modification
SD85_20660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SD85_20665	COG1847	R3H domain protein
SD85_20670	COG0706	membrane insertase activity
SD85_20675	COG0594	ribonuclease P activity
SD85_20680	COG0230	Belongs to the bacterial ribosomal protein bL34 family