locus-tag	class	description
GYO_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GYO_0002	COG0592	DNA-directed DNA polymerase activity
GYO_0003	COG2501	S4 domain
GYO_0004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GYO_0006	COG0187	DNA topoisomerase II activity
GYO_0008	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GYO_0013	COG0517	IMP dehydrogenase activity
GYO_0013	COG0516	GMP reductase activity
GYO_0014	COG1686	Belongs to the peptidase S11 family
GYO_0015	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GYO_0016	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GYO_0017	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GYO_0019	COG1428	Deoxynucleoside kinase
GYO_0020	COG1428	Deoxynucleoside kinase
GYO_0022	COG1335	isochorismatase
GYO_0023	COG0590	tRNA wobble adenosine to inosine editing
GYO_0024	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GYO_0025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GYO_0026	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GYO_0034	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GYO_0035	COG3853	Toxic anion resistance protein (TelA)
GYO_0036	COG1982	Orn Lys Arg decarboxylase major
GYO_0037	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GYO_0038	COG3870	Protein conserved in bacteria
GYO_0039	COG1728	Protein conserved in bacteria
GYO_0040	COG0470	DNA polymerase III
GYO_0041	COG1774	PSP1 C-terminal conserved region
GYO_0042	COG4467	Involved in initiation control of chromosome replication
GYO_0043	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GYO_0044	COG2827	Endonuclease containing a URI domain
GYO_0045	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GYO_0046	COG2002	toxin-antitoxin pair type II binding
GYO_0047	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYO_0047	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYO_0048	COG0084	hydrolase, TatD family'
GYO_0049	COG3583	domain protein
GYO_0049	COG3584	3D domain protein
GYO_0050	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GYO_0051	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GYO_0053	COG4466	Protein conserved in bacteria
GYO_0055	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GYO_0056	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GYO_0057	COG0251	oxidation-reduction process
GYO_0058	COG2088	sporulation resulting in formation of a cellular spore
GYO_0062	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GYO_0063	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GYO_0064	COG0193	aminoacyl-tRNA hydrolase activity
GYO_0066	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GYO_0067	COG2002	toxin-antitoxin pair type II binding
GYO_0068	COG2244	polysaccharide biosynthetic process
GYO_0069	COG3956	TIGRFAM MazG family protein
GYO_0070	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GYO_0073	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GYO_0074	COG1098	S1 RNA binding domain
GYO_0078	COG2304	oxidoreductase activity
GYO_0079	COG0515	serine threonine protein kinase
GYO_0080	COG0037	tRNA processing
GYO_0082	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GYO_0083	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GYO_0084	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GYO_0085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GYO_0086	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GYO_0089	COG0512	Glutamine amidotransferase of anthranilate synthase
GYO_0090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYO_0091	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GYO_0092	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GYO_0093	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GYO_0094	COG1396	sequence-specific DNA binding
GYO_0095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GYO_0096	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GYO_0109	COG4463	regulation of RNA biosynthetic process
GYO_0110	COG3880	PFAM UvrB UvrC protein
GYO_0111	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GYO_0112	COG0542	response to heat
GYO_0113	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GYO_0114	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GYO_0115	COG4956	integral membrane protein (PIN domain superfamily)
GYO_0116	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GYO_0117	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GYO_0118	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GYO_0121	COG1045	serine acetyltransferase
GYO_0122	COG0215	cysteine-tRNA ligase activity
GYO_0123	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GYO_0124	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYO_0125	COG3688	RNA-binding protein containing a PIN domain
GYO_0126	COG1595	DNA-templated transcription, initiation
GYO_0127	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GYO_0128	COG0250	Participates in transcription elongation, termination and antitermination
GYO_0129	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GYO_0130	COG0081	regulation of translation
GYO_0131	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GYO_0132	COG0222	ribosome binding
GYO_0133	COG2813	Specifically methylates the guanine in position
GYO_0134	COG0085	RNA polymerase activity
GYO_0135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GYO_0136	COG1358	cellular component organization or biogenesis
GYO_0137	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GYO_0138	COG0049	tRNA binding
GYO_0139	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GYO_0140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GYO_0141	COG0596	Alpha beta hydrolase
GYO_0142	COG0051	transcription antitermination factor activity, RNA binding
GYO_0143	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GYO_0144	COG0088	Forms part of the polypeptide exit tunnel
GYO_0145	COG0089	rRNA binding
GYO_0146	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GYO_0147	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GYO_0148	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GYO_0149	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GYO_0150	COG0255	Belongs to the universal ribosomal protein uL29 family
GYO_0151	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GYO_0152	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GYO_0154	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GYO_0156	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GYO_0157	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GYO_0158	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GYO_0160	COG1841	ribosomal large subunit assembly
GYO_0161	COG0200	Binds to the 23S rRNA
GYO_0162	COG0201	protein transport
GYO_0163	COG0563	adenylate kinase activity
GYO_0164	COG0024	Methionine aminopeptidase
GYO_0165	COG2163	COG2163 Ribosomal protein L14E L6E L27E
GYO_0166	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GYO_0167	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GYO_0168	COG0202	RNA polymerase activity
GYO_0169	COG0203	ribosomal protein L17
GYO_0170	COG1122	ATPase activity
GYO_0173	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GYO_0174	COG0101	tRNA pseudouridine synthase activity
GYO_0175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GYO_0176	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GYO_0178	COG2226	methyltransferase
GYO_0180	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYO_0181	COG0489	protein tyrosine kinase activity
GYO_0183	COG2194	sulfuric ester hydrolase activity
GYO_0184	COG0726	polysaccharide deacetylase
GYO_0190	COG2856	Zn peptidase
GYO_0192	COG1395	domain, Protein
GYO_0202	COG0305	Participates in initiation and elongation during chromosome replication
GYO_0203	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GYO_0210	COG1902	pentaerythritol trinitrate reductase activity
GYO_0223	COG1783	phage Terminase large subunit
GYO_0224	COG5518	Phage portal protein
GYO_0225	COG2369	cell adhesion
GYO_0227	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GYO_0228	COG4653	Phage capsid family
GYO_0239	COG5280	Phage tail tape measure protein TP901
GYO_0239	COG3953	SLT domain
GYO_0240	COG1652	LysM domain
GYO_0241	COG4193	domain, Protein
GYO_0243	COG3628	GPW Gp25 family protein
GYO_0244	COG3299	homolog of phage Mu protein gp47
GYO_0245	COG3778	Protein conserved in bacteria
GYO_0251	COG4824	toxin secretion phage lysis holin
GYO_0252	COG5632	N-Acetylmuramoyl-L-alanine amidase
GYO_0252	COG1388	LysM domain
GYO_0252	COG3409	Peptidoglycan-binding domain 1 protein
GYO_0254	COG5444	nuclease activity
GYO_0255	COG0457	Tetratricopeptide repeat
GYO_0269	COG2856	Zn peptidase
GYO_0271	COG1395	domain, Protein
GYO_0281	COG0305	Participates in initiation and elongation during chromosome replication
GYO_0282	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GYO_0289	COG1902	pentaerythritol trinitrate reductase activity
GYO_0302	COG1783	phage Terminase large subunit
GYO_0303	COG5518	Phage portal protein
GYO_0304	COG2369	cell adhesion
GYO_0306	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GYO_0307	COG4653	Phage capsid family
GYO_0318	COG5280	Phage tail tape measure protein TP901
GYO_0318	COG3953	SLT domain
GYO_0319	COG1652	LysM domain
GYO_0320	COG4193	domain, Protein
GYO_0322	COG3628	GPW Gp25 family protein
GYO_0323	COG3299	homolog of phage Mu protein gp47
GYO_0324	COG3778	Protein conserved in bacteria
GYO_0330	COG4824	toxin secretion phage lysis holin
GYO_0331	COG5632	N-Acetylmuramoyl-L-alanine amidase
GYO_0331	COG1388	LysM domain
GYO_0331	COG3409	Peptidoglycan-binding domain 1 protein
GYO_0333	COG5444	nuclease activity
GYO_0334	COG0457	Tetratricopeptide repeat
GYO_0345	COG0738	Major facilitator superfamily
GYO_0346	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GYO_0348	COG1063	alcohol dehydrogenase
GYO_0349	COG0659	secondary active sulfate transmembrane transporter activity
GYO_0350	COG0385	Bile acid
GYO_0351	COG2819	hydrolase of the alpha beta superfamily
GYO_0352	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_0353	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_0354	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYO_0355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYO_0355	COG2207	Transcriptional regulator
GYO_0357	COG3876	Protein conserved in bacteria
GYO_0358	COG1472	Belongs to the glycosyl hydrolase 3 family
GYO_0359	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GYO_0360	COG1263	PTS System
GYO_0360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_0361	COG1737	Transcriptional regulator
GYO_0362	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GYO_0363	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYO_0364	COG1683	Conserved Protein
GYO_0370	COG1595	DNA-templated transcription, initiation
GYO_0371	COG5662	AntiSigma factor
GYO_0372	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GYO_0373	COG4856	YbbR-like protein
GYO_0374	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYO_0376	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GYO_0377	COG3002	Belongs to the UPF0753 family
GYO_0378	COG0288	reversible hydration of carbon dioxide
GYO_0380	COG5609	conserved protein (DUF2294)
GYO_0382	COG0640	Transcriptional regulator
GYO_0383	COG2814	Major facilitator Superfamily
GYO_0384	COG1413	lyase activity
GYO_0386	COG0789	Transcriptional regulator
GYO_0387	COG0596	Alpha beta hydrolase
GYO_0388	COG0745	RESPONSE REGULATOR receiver
GYO_0389	COG0642	Histidine kinase
GYO_0392	COG0515	serine threonine protein kinase
GYO_0395	COG1113	amino acid transport
GYO_0398	COG2602	Beta-lactamase
GYO_0400	COG2124	cytochrome p450
GYO_0402	COG1283	sodium-dependent phosphate transmembrane transporter activity
GYO_0403	COG0584	glycerophosphoryl diester phosphodiesterase
GYO_0404	COG2271	Major facilitator Superfamily
GYO_0407	COG1846	Transcriptional regulator
GYO_0407	COG0456	acetyltransferase
GYO_0408	COG2271	Major facilitator Superfamily
GYO_0410	COG3409	Peptidoglycan-binding domain 1 protein
GYO_0413	COG1917	Cupin 2, conserved barrel domain protein
GYO_0413	COG2207	Transcriptional regulator
GYO_0417	COG3179	chitinase
GYO_0422	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GYO_0423	COG3591	Belongs to the peptidase S1B family
GYO_0425	COG0596	Alpha beta hydrolase
GYO_0426	COG1183	phosphatidylcholine synthase activity
GYO_0428	COG0688	phosphatidylethanolamine metabolic process
GYO_0430	COG2312	Erythromycin esterase
GYO_0432	COG1301	dicarboxylic acid transport
GYO_0433	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_0433	COG1263	PTS System
GYO_0433	COG2190	(PTS) system
GYO_0434	COG0363	glucosamine-6-phosphate deaminase activity
GYO_0437	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYO_0438	COG0833	amino acid
GYO_0439	COG2040	homocysteine
GYO_0440	COG1115	amino acid carrier protein
GYO_0441	COG2066	Belongs to the glutaminase family
GYO_0443	COG0784	Response regulator, receiver
GYO_0445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYO_0446	COG1012	belongs to the aldehyde dehydrogenase family
GYO_0447	COG2271	Major facilitator Superfamily
GYO_0448	COG4948	Mandelate Racemase Muconate Lactonizing
GYO_0449	COG2186	Transcriptional regulator
GYO_0450	COG2721	sulfolactate sulfo-lyase activity
GYO_0451	COG3173	Aminoglycoside phosphotransferase
GYO_0453	COG0697	spore germination
GYO_0454	COG0745	RESPONSE REGULATOR receiver
GYO_0455	COG2205	protein histidine kinase activity
GYO_0456	COG1131	(ABC) transporter
GYO_0460	COG3773	Cell wall hydrolase
GYO_0461	COG2304	oxidoreductase activity
GYO_0463	COG3540	Alkaline phosphatase
GYO_0464	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GYO_0465	COG0805	protein transport
GYO_0466	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GYO_0467	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GYO_0468	COG0477	Major facilitator Superfamily
GYO_0469	COG1309	transcriptional regulator
GYO_0470	COG0252	asparaginase activity
GYO_0471	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GYO_0472	COG1714	RDD family
GYO_0473	COG3012	SEC-C Motif Domain Protein
GYO_0473	COG1405	negative regulation of cell septum assembly
GYO_0474	COG3290	protein histidine kinase activity
GYO_0475	COG3279	Response regulator of the LytR AlgR family
GYO_0476	COG4555	ABC transporter
GYO_0477	COG1668	transmembrane transport
GYO_0478	COG0667	Aldo Keto reductase
GYO_0480	COG1595	DNA-templated transcription, initiation
GYO_0482	COG1595	DNA-templated transcription, initiation
GYO_0483	COG1876	peptidase activity
GYO_0484	COG0457	Tetratricopeptide repeat
GYO_0485	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_0486	COG0366	Alpha amylase catalytic
GYO_0488	COG0803	Belongs to the bacterial solute-binding protein 9 family
GYO_0489	COG1121	(ABC) transporter
GYO_0492	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GYO_0493	COG2310	stress, protein
GYO_0494	COG2310	stress, protein
GYO_0495	COG2310	stress, protein
GYO_0496	COG0861	Integral membrane protein TerC family
GYO_0498	COG3853	Toxic anion resistance protein (TelA)
GYO_0499	COG0477	Major facilitator Superfamily
GYO_0500	COG2814	Major facilitator Superfamily
GYO_0501	COG0640	Transcriptional regulator
GYO_0502	COG0517	IMP dehydrogenase activity
GYO_0502	COG4175	Glycine betaine
GYO_0503	COG4176	ABC-type proline glycine betaine transport system permease component
GYO_0504	COG2113	Glycine betaine
GYO_0505	COG1473	amidohydrolase
GYO_0506	COG1288	antiporter activity
GYO_0508	COG0366	Alpha amylase catalytic
GYO_0510	COG1620	l-lactate permease
GYO_0511	COG2814	Major facilitator Superfamily
GYO_0512	COG1846	Transcriptional regulator
GYO_0513	COG1280	lysine exporter protein (LysE YggA)
GYO_0514	COG3403	YqcI/YcgG family
GYO_0515	COG1113	amino acid transport
GYO_0516	COG3665	Urea carboxylase-associated protein
GYO_0517	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GYO_0518	COG1660	Displays ATPase and GTPase activities
GYO_0520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GYO_0521	COG2226	methyltransferase
GYO_0522	COG0583	DNA-binding transcription factor activity
GYO_0523	COG3458	cephalosporin-C deacetylase activity
GYO_0524	COG3541	Predicted nucleotidyltransferase
GYO_0525	COG0506	proline dehydrogenase activity
GYO_0528	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYO_0529	COG2508	Transcriptional regulator
GYO_0530	COG3689	TIGRFAM TIGR03943 family protein
GYO_0531	COG0701	Predicted permease
GYO_0532	COG2267	carboxylic ester hydrolase activity
GYO_0535	COG1587	Uroporphyrinogen-III synthase
GYO_0535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GYO_0536	COG2146	nitrite reductase [NAD(P)H] activity
GYO_0537	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GYO_0538	COG0243	molybdopterin cofactor binding
GYO_0539	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GYO_0540	COG2223	nitrite transmembrane transporter activity
GYO_0541	COG1469	GTP cyclohydrolase I activity
GYO_0542	COG1376	ErfK ybiS ycfS ynhG family protein
GYO_0544	COG0523	cobalamin synthesis protein
GYO_0545	COG0765	amino acid transport
GYO_0546	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GYO_0549	COG1714	RDD family
GYO_0551	COG1846	Transcriptional regulator
GYO_0553	COG3842	ATPase activity
GYO_0554	COG2723	6-phospho-beta-galactosidase activity
GYO_0556	COG3209	COG3209 Rhs family protein
GYO_0557	COG3290	protein histidine kinase activity
GYO_0557	COG0840	transmembrane signaling receptor activity
GYO_0558	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GYO_0559	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GYO_0560	COG1733	regulation of RNA biosynthetic process
GYO_0563	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GYO_0564	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GYO_0565	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GYO_0566	COG2814	Major facilitator Superfamily
GYO_0568	COG0697	spore germination
GYO_0569	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYO_0571	COG2364	Membrane
GYO_0573	COG0457	Tetratricopeptide repeat
GYO_0574	COG1126	abc transporter atp-binding protein
GYO_0575	COG0765	amino acid transport
GYO_0576	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GYO_0577	COG0583	DNA-binding transcription factor activity
GYO_0578	COG0163	prenyltransferase activity
GYO_0579	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GYO_0582	COG0596	Alpha beta hydrolase
GYO_0583	COG3104	oligopeptide transport
GYO_0584	COG5434	Belongs to the glycosyl hydrolase 28 family
GYO_0586	COG0697	spore germination
GYO_0588	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GYO_0589	COG1136	(ABC) transporter
GYO_0590	COG0577	efflux transmembrane transporter activity
GYO_0591	COG0745	RESPONSE REGULATOR receiver
GYO_0592	COG5002	protein histidine kinase activity
GYO_0592	COG3850	Histidine kinase
GYO_0593	COG0457	Tetratricopeptide repeat
GYO_0595	COG0527	aspartate kinase activity
GYO_0596	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_0597	COG4605	iron ion homeostasis
GYO_0598	COG4604	ABC transporter, ATP-binding protein
GYO_0599	COG4607	ABC-type enterochelin transport system periplasmic component
GYO_0600	COG2814	Major facilitator Superfamily
GYO_0601	COG1309	transcriptional regulator
GYO_0602	COG0778	Nitroreductase
GYO_0603	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GYO_0604	COG0640	Transcriptional regulator
GYO_0605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYO_0606	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GYO_0607	COG1012	belongs to the aldehyde dehydrogenase family
GYO_0609	COG4975	Glucose uptake
GYO_0610	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_0611	COG4549	nuclear export factor GLE1
GYO_0612	COG2372	response to copper ion
GYO_0612	COG1276	copper resistance
GYO_0613	COG1349	DNA-binding transcription factor activity
GYO_0615	COG2213	PTS system mannitol-specific
GYO_0616	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_0617	COG0246	Mannitol dehydrogenase
GYO_0618	COG0473	3-isopropylmalate dehydrogenase activity
GYO_0619	COG0412	Dienelactone hydrolase
GYO_0620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GYO_0622	COG0561	phosphatase activity
GYO_0623	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GYO_0624	COG1914	H( )-stimulated, divalent metal cation uptake system
GYO_0625	COG4336	lyase activity
GYO_0626	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GYO_0627	COG1984	allophanate hydrolase subunit 2
GYO_0628	COG1414	Transcriptional regulator
GYO_0629	COG2755	lipolytic protein G-D-S-L family
GYO_0631	COG2329	Antibiotic biosynthesis monooxygenase
GYO_0632	COG0768	penicillin binding
GYO_0633	COG4989	oxidoreductase activity
GYO_0634	COG3711	transcriptional antiterminator
GYO_0635	COG0318	PFAM AMP-dependent synthetase and ligase
GYO_0636	COG2226	methyltransferase
GYO_0637	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_0638	COG1917	Cupin 2, conserved barrel domain protein
GYO_0639	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYO_0640	COG3871	stress protein (general stress protein 26)
GYO_0642	COG2814	Major facilitator Superfamily
GYO_0643	COG1522	sequence-specific DNA binding
GYO_0644	COG0551	DNA topoisomerase type I activity
GYO_0644	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GYO_0645	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GYO_0646	COG3706	GGDEF domain
GYO_0647	COG5298	Protein conserved in bacteria
GYO_0648	COG1215	transferase activity, transferring glycosyl groups
GYO_0650	COG0531	amino acid
GYO_0651	COG0494	nUDIX hydrolase
GYO_0652	COG0028	Belongs to the TPP enzyme family
GYO_0655	COG1914	H( )-stimulated, divalent metal cation uptake system
GYO_0656	COG2261	transglycosylase associated protein
GYO_0657	COG4876	unkown
GYO_0658	COG2217	Heavy metal translocating P-type atpase
GYO_0659	COG3729	General stress protein
GYO_0660	COG0662	Cupin 2, conserved barrel domain protein
GYO_0661	COG2329	Antibiotic biosynthesis monooxygenase
GYO_0662	COG3546	catalase activity
GYO_0663	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GYO_0664	COG3290	protein histidine kinase activity
GYO_0665	COG4565	transcriptional regulatory protein
GYO_0666	COG1301	dicarboxylic acid transport
GYO_0667	COG0628	permease
GYO_0668	COG1301	dicarboxylic acid transport
GYO_0669	COG1131	(ABC) transporter
GYO_0670	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GYO_0672	COG1960	acyl-CoA dehydrogenase activity
GYO_0675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GYO_0676	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_0677	COG1181	Belongs to the D-alanine--D-alanine ligase family
GYO_0678	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GYO_0679	COG0513	Belongs to the DEAD box helicase family
GYO_0680	COG3402	PFAM membrane-flanked domain
GYO_0681	COG3428	Bacterial PH domain
GYO_0682	COG0705	Rhomboid family
GYO_0683	COG0736	holo-[acyl-carrier-protein] synthase activity
GYO_0685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GYO_0686	COG0864	Transcriptional regulator
GYO_0687	COG2337	Toxic component of a toxin-antitoxin (TA) module
GYO_0688	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_0689	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_0690	COG2172	sigma factor antagonist activity
GYO_0691	COG2208	phosphoserine phosphatase activity
GYO_0692	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_0693	COG2172	sigma factor antagonist activity
GYO_0694	COG1191	sigma factor activity
GYO_0695	COG2208	phosphoserine phosphatase activity
GYO_0696	COG2183	response to ionizing radiation
GYO_0698	COG3091	SprT-like family
GYO_0707	COG2814	Major facilitator Superfamily
GYO_0708	COG4221	oxidoreductase activity
GYO_0711	COG1309	transcriptional regulator
GYO_0715	COG1522	sequence-specific DNA binding
GYO_0716	COG1309	transcriptional regulator
GYO_0719	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GYO_0720	COG1522	sequence-specific DNA binding
GYO_0721	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GYO_0722	COG2814	Major facilitator Superfamily
GYO_0723	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYO_0724	COG2807	transmembrane transport
GYO_0725	COG0583	DNA-binding transcription factor activity
GYO_0726	COG2258	MOSC domain
GYO_0727	COG1280	lysine exporter protein (LysE YggA)
GYO_0730	COG3239	Fatty acid desaturase
GYO_0732	COG1278	Cold shock
GYO_0733	COG1329	Transcriptional regulator
GYO_0738	COG2807	transmembrane transport
GYO_0739	COG1396	sequence-specific DNA binding
GYO_0740	COG2207	Transcriptional regulator
GYO_0740	COG3708	Transcriptional regulator
GYO_0742	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GYO_0746	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_0747	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_0748	COG1309	transcriptional regulator
GYO_0750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GYO_0751	COG1522	sequence-specific DNA binding
GYO_0752	COG0697	spore germination
GYO_0753	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYO_0754	COG2030	dehydratase
GYO_0755	COG3545	Serine hydrolase
GYO_0756	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYO_0757	COG1733	regulation of RNA biosynthetic process
GYO_0758	COG2249	NAD(P)H dehydrogenase (quinone) activity
GYO_0760	COG0640	Transcriptional regulator
GYO_0761	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GYO_0762	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GYO_0763	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYO_0765	COG0726	polysaccharide deacetylase
GYO_0767	COG5002	protein histidine kinase activity
GYO_0768	COG0745	RESPONSE REGULATOR receiver
GYO_0769	COG0697	spore germination
GYO_0770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYO_0771	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GYO_0772	COG0640	Transcriptional regulator
GYO_0773	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GYO_0776	COG4585	Histidine kinase
GYO_0777	COG2197	response regulator
GYO_0778	COG2409	Drug exporters of the RND superfamily
GYO_0782	COG1114	Component of the transport system for branched-chain amino acids
GYO_0784	COG1811	Na channel or pump
GYO_0785	COG0789	Transcriptional regulator
GYO_0785	COG4978	Transcriptional regulator
GYO_0786	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GYO_0787	COG0778	Nitroreductase
GYO_0788	COG0346	lactoylglutathione lyase activity
GYO_0789	COG2259	Doxx family
GYO_0790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_0798	COG0071	Belongs to the small heat shock protein (HSP20) family
GYO_0802	COG1309	transcriptional regulator
GYO_0804	COG0456	acetyltransferase
GYO_0807	COG0673	inositol 2-dehydrogenase activity
GYO_0808	COG1609	Transcriptional regulator
GYO_0809	COG2814	Major facilitator Superfamily
GYO_0811	COG2814	Major facilitator Superfamily
GYO_0814	COG1113	amino acid transport
GYO_0815	COG2318	DinB family
GYO_0816	COG1846	Transcriptional regulator
GYO_0817	COG2409	Drug exporters of the RND superfamily
GYO_0817	COG1033	growth of symbiont in host cell
GYO_0818	COG0778	Nitroreductase
GYO_0819	COG1846	Transcriptional regulator
GYO_0820	COG1396	sequence-specific DNA binding
GYO_0824	COG2814	Major facilitator Superfamily
GYO_0826	COG2801	Transposase and inactivated derivatives
GYO_0827	COG0730	response to heat
GYO_0828	COG1802	Transcriptional regulator
GYO_0829	COG1388	LysM domain
GYO_0829	COG3858	chitin binding
GYO_0830	COG1819	glycosyl
GYO_0832	COG1785	Belongs to the alkaline phosphatase family
GYO_0835	COG0454	-acetyltransferase
GYO_0836	COG1078	dGTPase activity
GYO_0837	COG1388	LysM domain
GYO_0838	COG2814	Major facilitator Superfamily
GYO_0839	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GYO_0840	COG1447	Phosphotransferase system cellobiose-specific component IIA
GYO_0841	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GYO_0842	COG2723	6-phospho-beta-galactosidase activity
GYO_0843	COG2188	Transcriptional regulator
GYO_0844	COG1940	carbohydrate kinase activity
GYO_0845	COG1482	cell wall glycoprotein biosynthetic process
GYO_0846	COG4124	Belongs to the glycosyl hydrolase 26 family
GYO_0853	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GYO_0854	COG0802	atpase or kinase
GYO_0855	COG1214	PFAM Peptidase M22, glycoprotease
GYO_0856	COG0456	acetyltransferase
GYO_0857	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GYO_0859	COG0488	(ABC) transporter
GYO_0860	COG0315	cyclic pyranopterin monophosphate synthase activity
GYO_0861	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GYO_0862	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GYO_0863	COG0805	protein transport
GYO_0865	COG1266	CAAX protease self-immunity
GYO_0866	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GYO_0867	COG0459	protein refolding
GYO_0870	COG0457	Tetratricopeptide repeat
GYO_0871	COG1063	alcohol dehydrogenase
GYO_0872	COG2211	Major facilitator Superfamily
GYO_0873	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYO_0874	COG1842	Phage shock protein A
GYO_0875	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GYO_0876	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GYO_0877	COG4260	virion core protein, lumpy skin disease virus
GYO_0879	COG2814	Major facilitator Superfamily
GYO_0880	COG1063	alcohol dehydrogenase
GYO_0881	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GYO_0882	COG0823	Involved in the tonB-independent uptake of proteins
GYO_0885	COG2267	carboxylic ester hydrolase activity
GYO_0890	COG1113	amino acid transport
GYO_0891	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GYO_0892	COG0714	Associated with various cellular activities
GYO_0893	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GYO_0894	COG1305	Transglutaminase-like
GYO_0895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GYO_0895	COG0519	Catalyzes the synthesis of GMP from XMP
GYO_0897	COG2252	PERMEase
GYO_0898	COG3064	Membrane
GYO_0900	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GYO_0902	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GYO_0903	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GYO_0904	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GYO_0905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GYO_0906	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GYO_0907	COG0047	phosphoribosylformylglycinamidine synthase activity
GYO_0908	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GYO_0909	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GYO_0910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GYO_0911	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GYO_0912	COG0138	bifunctional purine biosynthesis protein purh
GYO_0913	COG0151	Belongs to the GarS family
GYO_0914	COG1522	sequence-specific DNA binding
GYO_0915	COG0531	amino acid
GYO_0918	COG1470	cell adhesion involved in biofilm formation
GYO_0919	COG4496	protein, YerC YecD
GYO_0920	COG0069	glutamate synthase activity
GYO_0922	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GYO_0923	COG0210	DNA helicase
GYO_0924	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GYO_0925	COG4851	CamS sex pheromone cAM373 precursor
GYO_0926	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GYO_0927	COG1285	pathogenesis
GYO_0928	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYO_0930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GYO_0931	COG0154	amidase activity
GYO_0932	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GYO_0933	COG1309	transcriptional regulator
GYO_0935	COG1597	lipid kinase activity
GYO_0936	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GYO_0939	COG5444	nuclease activity
GYO_0941	COG3586	endonuclease activity
GYO_0942	COG3391	amine dehydrogenase activity
GYO_0945	COG0217	transcriptional regulatory protein
GYO_0947	COG1309	transcriptional regulator
GYO_0948	COG3631	Ketosteroid isomerase-related protein
GYO_0949	COG0702	epimerase
GYO_0952	COG3546	catalase activity
GYO_0953	COG0454	-acetyltransferase
GYO_0954	COG5578	integral membrane protein
GYO_0955	COG2972	Histidine kinase
GYO_0956	COG4753	response regulator
GYO_0956	COG2207	Transcriptional regulator
GYO_0957	COG1653	transport
GYO_0958	COG1175	transmembrane transport
GYO_0959	COG0395	ABC-type sugar transport system, permease component
GYO_0960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GYO_0961	COG2207	Transcriptional regulator
GYO_0962	COG2755	lipolytic protein G-D-S-L family
GYO_0964	COG5578	integral membrane protein
GYO_0965	COG3401	FG-GAP repeat protein
GYO_0966	COG3401	FG-GAP repeat protein
GYO_0967	COG2755	lipolytic protein G-D-S-L family
GYO_0968	COG1874	Beta-galactosidase
GYO_0970	COG1653	transport
GYO_0971	COG4209	transmembrane transport
GYO_0972	COG0395	ABC-type sugar transport system, permease component
GYO_0973	COG1486	melibiose metabolic process
GYO_0974	COG2323	membrane
GYO_0975	COG2329	Antibiotic biosynthesis monooxygenase
GYO_0976	COG0346	lactoylglutathione lyase activity
GYO_0979	COG5583	Uncharacterized small protein (DUF2292)
GYO_0980	COG0670	Belongs to the BI1 family
GYO_0981	COG0697	spore germination
GYO_0982	COG1846	Transcriptional regulator
GYO_0983	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GYO_0984	COG1715	Restriction endonuclease
GYO_0986	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GYO_0986	COG2124	cytochrome p450
GYO_0987	COG1368	sulfuric ester hydrolase activity
GYO_0989	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GYO_0990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYO_0991	COG1442	glycosyl transferase family 8
GYO_0993	COG1442	glycosyl transferase family 8
GYO_0994	COG2223	nitrite transmembrane transporter activity
GYO_0997	COG0531	amino acid
GYO_0998	COG1012	belongs to the aldehyde dehydrogenase family
GYO_1000	COG0488	(ABC) transporter
GYO_1002	COG0789	Transcriptional regulator
GYO_1003	COG2814	Major facilitator Superfamily
GYO_1007	COG0488	(ABC) transporter
GYO_1008	COG0513	Belongs to the DEAD box helicase family
GYO_1009	COG0456	acetyltransferase
GYO_1010	COG2130	NADP-dependent
GYO_1012	COG2211	Major facilitator Superfamily
GYO_1013	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYO_1014	COG1120	ATPase activity
GYO_1015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_1016	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_1017	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GYO_1020	COG3866	Pectate lyase
GYO_1021	COG0471	metal ion transport
GYO_1023	COG3290	protein histidine kinase activity
GYO_1024	COG4565	transcriptional regulatory protein
GYO_1025	COG3181	Tripartite tricarboxylate transporter family receptor
GYO_1027	COG2851	Citrate transporter
GYO_1028	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_1029	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GYO_1030	COG1254	Belongs to the acylphosphatase family
GYO_1031	COG2258	MOSC domain
GYO_1036	COG0024	Methionine aminopeptidase
GYO_1037	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_1037	COG1263	PTS System
GYO_1038	COG1368	sulfuric ester hydrolase activity
GYO_1040	COG1115	amino acid carrier protein
GYO_1041	COG0531	amino acid
GYO_1044	COG0697	spore germination
GYO_1045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_1045	COG1263	PTS System
GYO_1046	COG0366	Alpha amylase catalytic
GYO_1047	COG2188	Transcriptional regulator
GYO_1048	COG0778	Nitroreductase
GYO_1049	COG0737	Belongs to the 5'-nucleotidase family
GYO_1051	COG0693	protein deglycase activity
GYO_1052	COG2814	Major facilitator Superfamily
GYO_1054	COG4840	Belongs to the UPF0435 family
GYO_1055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GYO_1056	COG4980	gas vesicle protein
GYO_1057	COG1295	ribonuclease BN
GYO_1058	COG0477	Major facilitator Superfamily
GYO_1059	COG0387	Pfam Sodium calcium exchanger
GYO_1061	COG0668	transmembrane transport
GYO_1062	COG0535	radical SAM domain protein
GYO_1064	COG0726	polysaccharide deacetylase
GYO_1065	COG2084	Dehydrogenase
GYO_1066	COG0598	Magnesium transport protein CorA
GYO_1067	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GYO_1068	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GYO_1069	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GYO_1071	COG4637	Psort location Cytoplasmic, score
GYO_1075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GYO_1076	COG0022	dehydrogenase e1 component
GYO_1077	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYO_1078	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYO_1079	COG3284	Transcriptional regulator
GYO_1081	COG1742	UPF0060 membrane protein
GYO_1085	COG4842	Belongs to the WXG100 family
GYO_1086	COG1486	melibiose metabolic process
GYO_1087	COG1737	Transcriptional regulator
GYO_1088	COG1263	PTS System
GYO_1088	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_1089	COG1132	(ABC) transporter
GYO_1090	COG1132	(ABC) transporter
GYO_1091	COG2259	Doxx family
GYO_1092	COG2514	catechol 2,3-dioxygenase activity
GYO_1093	COG1917	Cupin 2, conserved barrel domain protein
GYO_1093	COG4977	sequence-specific DNA binding
GYO_1094	COG2814	Major facilitator Superfamily
GYO_1095	COG1082	Xylose isomerase domain protein TIM barrel
GYO_1096	COG0673	inositol 2-dehydrogenase activity
GYO_1097	COG4585	Histidine kinase
GYO_1098	COG2197	response regulator
GYO_1100	COG1131	(ABC) transporter
GYO_1101	COG1511	domain protein
GYO_1101	COG0842	Transport permease protein
GYO_1102	COG0842	Transport permease protein
GYO_1104	COG1695	Transcriptional regulator
GYO_1105	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GYO_1106	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GYO_1108	COG2318	DinB family
GYO_1109	COG2814	Major facilitator Superfamily
GYO_1110	COG1846	Transcriptional regulator
GYO_1111	COG0392	lysyltransferase activity
GYO_1111	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GYO_1112	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYO_1113	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_1114	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_1116	COG0384	phenazine biosynthesis protein PhzF
GYO_1117	COG0778	Nitroreductase
GYO_1119	COG1090	epimerase
GYO_1120	COG2137	regulation of response to DNA damage stimulus
GYO_1122	COG2814	Major facilitator Superfamily
GYO_1125	COG3103	Sh3 type 3 domain protein
GYO_1126	COG5658	integral membrane protein
GYO_1127	COG0596	Alpha beta hydrolase
GYO_1128	COG0463	Glycosyl transferase, family 2
GYO_1129	COG4485	Bacterial membrane protein, YfhO
GYO_1130	COG1988	membrane-bound metal-dependent
GYO_1131	COG1194	a g-specific adenine glycosylase
GYO_1133	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_1136	COG3557	Belongs to the UPF0374 family
GYO_1137	COG1132	(ABC) transporter
GYO_1138	COG4129	membrane
GYO_1139	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GYO_1140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GYO_1141	COG0735	belongs to the Fur family
GYO_1161	COG4326	sporulation control protein
GYO_1163	COG5577	PFAM Coat F domain
GYO_1164	COG3340	Belongs to the peptidase S51 family
GYO_1166	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GYO_1168	COG0753	catalase activity
GYO_1169	COG1116	anion transmembrane transporter activity
GYO_1170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GYO_1171	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GYO_1172	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GYO_1174	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GYO_1176	COG1476	TRANSCRIPTIONal
GYO_1178	COG3382	B3 4 domain protein
GYO_1179	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GYO_1181	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GYO_1182	COG0789	Transcriptional regulator
GYO_1183	COG1664	Polymer-forming cytoskeletal
GYO_1184	COG1664	Polymer-forming cytoskeletal
GYO_1186	COG2766	serine protein kinase
GYO_1187	COG2718	Belongs to the UPF0229 family
GYO_1188	COG1846	Transcriptional regulator
GYO_1189	COG1566	PFAM secretion protein HlyD family protein
GYO_1190	COG2814	Major facilitator Superfamily
GYO_1191	COG0655	NAD(P)H dehydrogenase (quinone) activity
GYO_1194	COG1725	Transcriptional regulator
GYO_1195	COG1131	(ABC) transporter
GYO_1196	COG1131	(ABC) transporter
GYO_1197	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GYO_1198	COG1278	Cold shock
GYO_1199	COG1464	Belongs to the NlpA lipoprotein family
GYO_1200	COG3706	GGDEF domain
GYO_1201	COG1823	symporter activity
GYO_1206	COG0737	Belongs to the 5'-nucleotidase family
GYO_1206	COG1525	nuclease
GYO_1206	COG4085	toxin activity
GYO_1207	COG3764	Sortase (surface protein transpeptidase)
GYO_1208	COG0564	pseudouridine synthase activity
GYO_1210	COG0517	IMP dehydrogenase activity
GYO_1211	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GYO_1212	COG3153	acetyltransferase
GYO_1212	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYO_1214	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GYO_1215	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GYO_1216	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GYO_1217	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GYO_1218	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GYO_1219	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYO_1220	COG2203	Gaf domain
GYO_1220	COG4585	Histidine kinase
GYO_1221	COG2197	response regulator
GYO_1222	COG0431	NADPH-dependent FMN reductase
GYO_1225	COG1388	LysM domain
GYO_1225	COG0791	NLP P60 protein
GYO_1226	COG1959	2 iron, 2 sulfur cluster binding
GYO_1227	COG0668	transmembrane transport
GYO_1229	COG1785	Belongs to the alkaline phosphatase family
GYO_1230	COG1388	LysM domain
GYO_1230	COG0791	NLP P60 protein
GYO_1231	COG0583	DNA-binding transcription factor activity
GYO_1232	COG0372	Belongs to the citrate synthase family
GYO_1233	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_1234	COG0531	amino acid
GYO_1236	COG0733	neurotransmitter:sodium symporter activity
GYO_1237	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYO_1238	COG0456	acetyltransferase
GYO_1241	COG1595	DNA-templated transcription, initiation
GYO_1242	COG0667	Aldo Keto reductase
GYO_1243	COG0204	Acyl-transferase
GYO_1244	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYO_1246	COG1253	flavin adenine dinucleotide binding
GYO_1247	COG0789	Transcriptional regulator
GYO_1248	COG0436	Aminotransferase
GYO_1250	COG1253	flavin adenine dinucleotide binding
GYO_1251	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GYO_1252	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GYO_1253	COG0584	glycerophosphoryl diester phosphodiesterase
GYO_1255	COG0668	transmembrane transport
GYO_1256	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GYO_1257	COG0726	polysaccharide deacetylase
GYO_1258	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYO_1259	COG1757	Na H antiporter
GYO_1260	COG0589	response to stress
GYO_1262	COG1132	(ABC) transporter
GYO_1263	COG1132	(ABC) transporter
GYO_1264	COG0702	epimerase
GYO_1269	COG0189	ligase activity
GYO_1270	COG0189	ligase activity
GYO_1271	COG4399	Belongs to the UPF0754 family
GYO_1272	COG3679	Belongs to the UPF0342 family
GYO_1273	COG4335	DNA alkylation repair
GYO_1274	COG0561	phosphatase activity
GYO_1275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYO_1276	COG0475	glutathione-regulated potassium exporter activity
GYO_1277	COG0490	domain, Protein
GYO_1279	COG1024	Enoyl-CoA hydratase
GYO_1281	COG4152	abc transporter atp-binding protein
GYO_1282	COG1668	transmembrane transport
GYO_1283	COG0420	3'-5' exonuclease activity
GYO_1284	COG4717	serine-type aminopeptidase activity
GYO_1285	COG3481	metal-dependent phosphohydrolase, HD sub domain
GYO_1287	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GYO_1292	COG1846	Transcriptional regulator
GYO_1293	COG4980	gas vesicle protein
GYO_1296	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GYO_1297	COG0537	adenosine 5'-monophosphoramidase activity
GYO_1298	COG1131	(ABC) transporter
GYO_1299	COG4473	ABC transporter
GYO_1301	COG1473	amidohydrolase
GYO_1303	COG3069	C4-dicarboxylate transmembrane transporter activity
GYO_1305	COG2329	Antibiotic biosynthesis monooxygenase
GYO_1306	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYO_1307	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GYO_1311	COG1309	transcriptional regulator
GYO_1312	COG1511	domain protein
GYO_1313	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYO_1314	COG4377	Putative membrane peptidase family (DUF2324)
GYO_1318	COG1363	Peptidase, m42
GYO_1319	COG4405	Protein conserved in bacteria
GYO_1320	COG1301	dicarboxylic acid transport
GYO_1322	COG1234	tRNA 3'-trailer cleavage
GYO_1323	COG0095	Lipoate-protein ligase
GYO_1324	COG0702	epimerase
GYO_1325	COG0318	PFAM AMP-dependent synthetase and ligase
GYO_1327	COG0501	Belongs to the peptidase M48B family
GYO_1328	COG1404	Belongs to the peptidase S8 family
GYO_1331	COG0456	acetyltransferase
GYO_1333	COG0604	alcohol dehydrogenase
GYO_1335	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GYO_1336	COG0406	alpha-ribazole phosphatase activity
GYO_1337	COG0183	Belongs to the thiolase family
GYO_1338	COG0318	PFAM AMP-dependent synthetase and ligase
GYO_1339	COG1268	BioY protein
GYO_1340	COG0840	transmembrane signaling receptor activity
GYO_1341	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYO_1341	COG0723	plastoquinol--plastocyanin reductase activity
GYO_1342	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_1344	COG4903	ComK protein
GYO_1345	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_1348	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYO_1351	COG0398	Pfam SNARE associated Golgi protein
GYO_1352	COG0681	Belongs to the peptidase S26 family
GYO_1353	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GYO_1354	COG1846	Transcriptional regulator
GYO_1356	COG0738	Major facilitator superfamily
GYO_1357	COG0673	inositol 2-dehydrogenase activity
GYO_1358	COG0561	phosphatase activity
GYO_1359	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYO_1360	COG1609	Transcriptional regulator
GYO_1361	COG3180	Ammonia monooxygenase
GYO_1362	COG0477	Major facilitator Superfamily
GYO_1362	COG2814	Major facilitator Superfamily
GYO_1363	COG4533	DNA binding
GYO_1365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GYO_1366	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GYO_1367	COG1074	ATP-dependent DNA helicase activity
GYO_1368	COG0420	3'-5' exonuclease activity
GYO_1369	COG0419	ATPase involved in DNA repair
GYO_1370	COG1403	HNH endonuclease
GYO_1378	COG5337	Spore coat protein CotH
GYO_1380	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYO_1382	COG1404	Belongs to the peptidase S8 family
GYO_1384	COG0367	asparagine synthase
GYO_1385	COG2318	DinB family
GYO_1387	COG1562	ergosterol biosynthetic process
GYO_1388	COG0534	Mate efflux family protein
GYO_1389	COG1917	Cupin 2, conserved barrel domain protein
GYO_1389	COG2207	Transcriptional regulator
GYO_1390	COG1609	Transcriptional regulator
GYO_1391	COG0673	inositol 2-dehydrogenase activity
GYO_1392	COG2318	DinB family
GYO_1393	COG1279	arginine transmembrane transporter activity
GYO_1394	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYO_1395	COG1357	PFAM Pentapeptide repeats (8 copies)
GYO_1396	COG2267	carboxylic ester hydrolase activity
GYO_1397	COG0529	Catalyzes the synthesis of activated sulfate
GYO_1398	COG2046	Belongs to the sulfate adenylyltransferase family
GYO_1399	COG0175	sulfate reduction
GYO_1400	COG2045	Belongs to the ComB family
GYO_1401	COG1809	phosphosulfolactate synthase activity
GYO_1402	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYO_1403	COG4948	Mandelate Racemase Muconate Lactonizing
GYO_1404	COG2814	Major facilitator Superfamily
GYO_1405	COG0454	-acetyltransferase
GYO_1406	COG2153	protein acetylation
GYO_1408	COG1666	GTP binding
GYO_1409	COG2996	Protein conserved in bacteria
GYO_1411	COG1307	EDD domain protein, DegV family
GYO_1412	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYO_1416	COG0561	phosphatase activity
GYO_1417	COG1073	alpha beta
GYO_1418	COG2151	metal-sulfur cluster biosynthetic enzyme
GYO_1422	COG2271	Major facilitator Superfamily
GYO_1423	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GYO_1426	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GYO_1427	COG0505	Belongs to the CarA family
GYO_1428	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GYO_1429	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GYO_1432	COG2267	carboxylic ester hydrolase activity
GYO_1434	COG1744	ABC transporter substrate-binding protein PnrA-like
GYO_1437	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYO_1438	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GYO_1439	COG5504	Zn-dependent protease
GYO_1440	COG0444	Belongs to the ABC transporter superfamily
GYO_1441	COG4608	Belongs to the ABC transporter superfamily
GYO_1443	COG0601	transmembrane transport
GYO_1444	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYO_1446	COG0180	Tryptophanyl-tRNA synthetase
GYO_1447	COG4166	transmembrane transport
GYO_1448	COG0601	transmembrane transport
GYO_1449	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYO_1450	COG0444	Belongs to the ABC transporter superfamily
GYO_1451	COG4608	Belongs to the ABC transporter superfamily
GYO_1452	COG2814	Major facilitator Superfamily
GYO_1453	COG0456	acetyltransferase
GYO_1454	COG1393	Belongs to the ArsC family
GYO_1455	COG0861	Integral membrane protein TerC family
GYO_1456	COG4862	establishment of competence for transformation
GYO_1457	COG4469	Competence protein
GYO_1458	COG1164	Oligoendopeptidase f
GYO_1461	COG2346	COG2346, Truncated hemoglobins
GYO_1462	COG0741	lytic transglycosylase activity
GYO_1463	COG4116	CYTH
GYO_1465	COG2357	RelA SpoT domain protein
GYO_1466	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GYO_1467	COG0564	pseudouridine synthase activity
GYO_1468	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GYO_1469	COG0569	domain protein
GYO_1469	COG0475	glutathione-regulated potassium exporter activity
GYO_1470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GYO_1471	COG0352	thiamine-phosphate diphosphorylase activity
GYO_1472	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYO_1473	COG2104	thiamine diphosphate biosynthetic process
GYO_1474	COG2022	thiamine diphosphate biosynthetic process
GYO_1475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GYO_1476	COG0351	phosphomethylpyrimidine kinase
GYO_1477	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GYO_1489	COG0210	DNA helicase
GYO_1491	COG2153	protein acetylation
GYO_1492	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GYO_1493	COG2382	esterase
GYO_1494	COG0626	cystathionine gamma-synthase activity
GYO_1495	COG0626	cystathionine gamma-synthase activity
GYO_1496	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYO_1501	COG0457	Tetratricopeptide repeat
GYO_1502	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GYO_1503	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_1503	COG3711	transcriptional antiterminator
GYO_1504	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYO_1504	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYO_1504	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_1505	COG1482	cell wall glycoprotein biosynthetic process
GYO_1507	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYO_1509	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GYO_1513	COG0109	protoheme IX farnesyltransferase activity
GYO_1515	COG0726	polysaccharide deacetylase
GYO_1521	COG2205	protein histidine kinase activity
GYO_1523	COG3383	formate dehydrogenase (NAD+) activity
GYO_1524	COG2427	Protein of unknown function (DUF1641)
GYO_1526	COG1051	belongs to the nudix hydrolase family
GYO_1528	COG2124	cytochrome p450
GYO_1529	COG1819	glycosyl
GYO_1531	COG1587	Uroporphyrinogen-III synthase
GYO_1532	COG0390	transport system, permease component
GYO_1533	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GYO_1534	COG0697	spore germination
GYO_1535	COG4297	protein containing double-stranded beta helix domain
GYO_1537	COG1252	NADH dehydrogenase
GYO_1539	COG1904	glucuronate isomerase
GYO_1540	COG2211	Major facilitator Superfamily
GYO_1541	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GYO_1542	COG1063	alcohol dehydrogenase
GYO_1543	COG1312	Catalyzes the dehydration of D-mannonate
GYO_1544	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_1545	COG2271	Major facilitator Superfamily
GYO_1546	COG1609	Transcriptional regulator
GYO_1547	COG0246	Mannitol dehydrogenase
GYO_1548	COG2721	sulfolactate sulfo-lyase activity
GYO_1549	COG0730	response to heat
GYO_1550	COG2318	DinB family
GYO_1551	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GYO_1552	COG0457	Tetratricopeptide repeat
GYO_1554	COG2350	Protein conserved in bacteria
GYO_1556	COG3409	Peptidoglycan-binding domain 1 protein
GYO_1556	COG1388	LysM domain
GYO_1556	COG5632	N-Acetylmuramoyl-L-alanine amidase
GYO_1558	COG4195	phage-related replication protein
GYO_1559	COG3546	catalase activity
GYO_1560	COG2856	Zn peptidase
GYO_1561	COG1396	sequence-specific DNA binding
GYO_1563	COG1522	sequence-specific DNA binding
GYO_1564	COG1484	DNA-dependent DNA replication
GYO_1568	COG1595	DNA-templated transcription, initiation
GYO_1569	COG5484	DNA packaging
GYO_1569	COG3728	DNA packaging
GYO_1570	COG1783	phage Terminase large subunit
GYO_1571	COG5518	Phage portal protein
GYO_1572	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GYO_1573	COG4653	Phage capsid family
GYO_1583	COG5412	phage tail tape measure protein
GYO_1583	COG3953	SLT domain
GYO_1583	COG5412	phage tail tape measure protein
GYO_1583	COG3953	SLT domain
GYO_1583	COG5412	phage tail tape measure protein
GYO_1583	COG3953	SLT domain
GYO_1584	COG1652	LysM domain
GYO_1585	COG4193	domain, Protein
GYO_1587	COG3628	GPW Gp25 family protein
GYO_1588	COG3299	homolog of phage Mu protein gp47
GYO_1589	COG3778	Protein conserved in bacteria
GYO_1597	COG3409	Peptidoglycan-binding domain 1 protein
GYO_1597	COG5632	N-Acetylmuramoyl-L-alanine amidase
GYO_1601	COG0306	phosphate transporter
GYO_1602	COG1392	Phosphate transport regulator
GYO_1603	COG0531	amino acid
GYO_1604	COG0346	lactoylglutathione lyase activity
GYO_1606	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GYO_1607	COG0463	Glycosyl transferase, family 2
GYO_1609	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYO_1610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYO_1611	COG2362	D-Aminopeptidase
GYO_1612	COG0601	transmembrane transport
GYO_1613	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYO_1614	COG0444	Belongs to the ABC transporter superfamily
GYO_1615	COG4166	transmembrane transport
GYO_1616	COG1619	proteins homologs of microcin C7 resistance protein MccF
GYO_1617	COG4948	Mandelate Racemase Muconate Lactonizing
GYO_1618	COG0791	NLP P60 protein
GYO_1619	COG4608	Belongs to the ABC transporter superfamily
GYO_1620	COG2706	6-phosphogluconolactonase activity
GYO_1621	COG1834	amidinotransferase
GYO_1622	COG1607	acyl-coa hydrolase
GYO_1623	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GYO_1623	COG1017	nitric oxide dioxygenase activity
GYO_1625	COG2323	membrane
GYO_1626	COG2318	DinB family
GYO_1627	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYO_1628	COG2076	Multidrug Resistance protein
GYO_1629	COG2076	Multidrug Resistance protein
GYO_1630	COG0788	formyltetrahydrofolate deformylase activity
GYO_1631	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GYO_1632	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GYO_1633	COG1764	response to oxidative stress
GYO_1634	COG1846	Transcriptional regulator
GYO_1635	COG1764	response to oxidative stress
GYO_1636	COG0463	Glycosyl transferase, family 2
GYO_1636	COG0457	Tetratricopeptide repeat
GYO_1637	COG0590	tRNA wobble adenosine to inosine editing
GYO_1639	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GYO_1641	COG1404	Belongs to the peptidase S8 family
GYO_1643	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_1644	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GYO_1645	COG1122	ATPase activity
GYO_1646	COG4721	ABC-type cobalt transport system, permease component
GYO_1648	COG0745	RESPONSE REGULATOR receiver
GYO_1650	COG3212	peptidase
GYO_1651	COG3212	peptidase
GYO_1654	COG2239	Acts as a magnesium transporter
GYO_1655	COG0789	Transcriptional regulator
GYO_1658	COG1846	Transcriptional regulator
GYO_1659	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GYO_1660	COG0726	polysaccharide deacetylase
GYO_1661	COG1408	metallophosphoesterase
GYO_1663	COG0463	Glycosyl transferase, family 2
GYO_1664	COG1793	dna ligase
GYO_1664	COG3285	dna ligase
GYO_1665	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GYO_1666	COG5001	Diguanylate cyclase
GYO_1666	COG3300	MHYT domain
GYO_1668	COG0586	Pfam SNARE associated Golgi protein
GYO_1669	COG0861	Integral membrane protein TerC family
GYO_1670	COG1191	sigma factor activity
GYO_1674	COG0501	Belongs to the peptidase M48B family
GYO_1675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GYO_1678	COG3594	Acyltransferase
GYO_1679	COG5002	protein histidine kinase activity
GYO_1680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GYO_1682	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GYO_1683	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GYO_1684	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYO_1685	COG0436	Aminotransferase
GYO_1686	COG1850	ribulose-bisphosphate carboxylase activity
GYO_1687	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GYO_1688	COG0235	Class ii aldolase
GYO_1689	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GYO_1690	COG3339	Conserved Protein
GYO_1694	COG3852	Histidine kinase
GYO_1695	COG1846	Transcriptional regulator
GYO_1696	COG1360	Flagellar Motor Protein
GYO_1697	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GYO_1698	COG0542	response to heat
GYO_1700	COG3949	Membrane
GYO_1701	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GYO_1702	COG0720	synthase
GYO_1703	COG0602	queuosine metabolic process
GYO_1704	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GYO_1707	COG1388	LysM domain
GYO_1708	COG3858	chitin binding
GYO_1710	COG4873	Protein conserved in bacteria
GYO_1713	COG3773	Cell wall hydrolase
GYO_1714	COG2244	polysaccharide biosynthetic process
GYO_1717	COG2217	Heavy metal translocating P-type atpase
GYO_1719	COG0006	proline dipeptidase activity
GYO_1721	COG1609	Transcriptional regulator
GYO_1722	COG3711	transcriptional antiterminator
GYO_1723	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_1723	COG2190	(PTS) system
GYO_1723	COG1263	PTS System
GYO_1724	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_1725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GYO_1727	COG1533	DNA photolyase activity
GYO_1728	COG0456	acetyltransferase
GYO_1729	COG0840	transmembrane signaling receptor activity
GYO_1730	COG2084	Dehydrogenase
GYO_1731	COG2340	Cysteine-rich secretory protein family
GYO_1732	COG0768	penicillin binding
GYO_1733	COG4191	Histidine kinase
GYO_1734	COG0436	Aminotransferase
GYO_1737	COG0784	Response regulator, receiver
GYO_1737	COG0835	chemotaxis
GYO_1739	COG2814	Major facilitator Superfamily
GYO_1740	COG1376	ErfK ybiS ycfS ynhG family protein
GYO_1741	COG1408	metallophosphoesterase
GYO_1742	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_1743	COG2200	EAL domain
GYO_1745	COG4703	Protein of unknown function (DUF1797)
GYO_1746	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GYO_1748	COG0517	IMP dehydrogenase activity
GYO_1749	COG0583	DNA-binding transcription factor activity
GYO_1750	COG0716	FMN binding
GYO_1752	COG0716	FMN binding
GYO_1753	COG2171	N-acyltransferase activity
GYO_1754	COG1473	amidohydrolase
GYO_1756	COG0668	transmembrane transport
GYO_1757	COG0450	alkyl hydroperoxide reductase
GYO_1758	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_1762	COG0746	molybdenum cofactor guanylyltransferase activity
GYO_1763	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GYO_1764	COG0303	'Molybdopterin
GYO_1765	COG1763	Mo-molybdopterin cofactor biosynthetic process
GYO_1766	COG0314	molybdopterin synthase activity
GYO_1767	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GYO_1768	COG1132	(ABC) transporter
GYO_1769	COG1132	(ABC) transporter
GYO_1771	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GYO_1772	COG1136	(ABC) transporter
GYO_1773	COG0577	efflux transmembrane transporter activity
GYO_1774	COG1349	DNA-binding transcription factor activity
GYO_1775	COG1105	Belongs to the carbohydrate kinase PfkB family
GYO_1776	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYO_1776	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYO_1776	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_1777	COG0681	Belongs to the peptidase S26 family
GYO_1779	COG0488	(ABC) transporter
GYO_1780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GYO_1781	COG2309	aminopeptidase activity
GYO_1783	COG1077	Cell shape determining protein MreB Mrl
GYO_1784	COG2002	toxin-antitoxin pair type II binding
GYO_1785	COG3852	Histidine kinase
GYO_1786	COG2105	PFAM AIG2 family protein
GYO_1786	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GYO_1787	COG0569	domain protein
GYO_1788	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYO_1789	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GYO_1792	COG0561	phosphatase activity
GYO_1793	COG0242	peptide deformylase activity
GYO_1796	COG0497	DNA recombination
GYO_1797	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GYO_1798	COG0022	dehydrogenase e1 component
GYO_1799	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYO_1800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYO_1801	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_1804	COG1982	Orn Lys Arg decarboxylase major
GYO_1805	COG4476	Belongs to the UPF0223 family
GYO_1806	COG4493	Belongs to the UPF0637 family
GYO_1808	COG0483	inositol monophosphate 1-phosphatase activity
GYO_1810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GYO_1815	COG1595	DNA-templated transcription, initiation
GYO_1821	COG4896	Protein conserved in bacteria
GYO_1823	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GYO_1824	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GYO_1825	COG2066	Belongs to the glutaminase family
GYO_1826	COG4838	Belongs to the UPF0358 family
GYO_1827	COG0772	Belongs to the SEDS family
GYO_1828	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GYO_1830	COG1612	heme a metabolic process
GYO_1831	COG0109	protoheme IX farnesyltransferase activity
GYO_1833	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GYO_1833	COG2010	Cytochrome c
GYO_1834	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GYO_1835	COG1845	cytochrome c oxidase, subunit III
GYO_1836	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GYO_1837	COG3336	cytochrome c oxidase
GYO_1839	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GYO_1840	COG2340	Cysteine-rich secretory protein family
GYO_1844	COG3679	Belongs to the UPF0342 family
GYO_1845	COG4471	UPF0298 protein
GYO_1846	COG0742	ribosomal rna small subunit methyltransferase
GYO_1847	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GYO_1848	COG3314	Sporulation integral membrane protein YlbJ
GYO_1849	COG1752	Esterase of the alpha-beta hydrolase superfamily
GYO_1850	COG3480	Lon protease (S16) C-terminal proteolytic domain
GYO_1851	COG1323	Belongs to the UPF0348 family
GYO_1853	COG1399	metal-binding, possibly nucleic acid-binding protein
GYO_1856	COG0454	-acetyltransferase
GYO_1857	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GYO_1858	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GYO_1859	COG2001	Belongs to the MraZ family
GYO_1860	COG0275	rRNA processing
GYO_1861	COG4839	cell division protein FtsL
GYO_1863	COG0768	penicillin binding
GYO_1864	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GYO_1865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYO_1866	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GYO_1867	COG0772	Belongs to the SEDS family
GYO_1868	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GYO_1869	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GYO_1870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GYO_1871	COG3879	Bacterial protein of unknown function (DUF881)
GYO_1872	COG3879	Bacterial protein of unknown function (DUF881)
GYO_1873	COG3856	small basic protein
GYO_1874	COG0849	cell division
GYO_1875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GYO_1877	COG4412	M6 family metalloprotease domain protein
GYO_1877	COG1404	Belongs to the peptidase S8 family
GYO_1879	COG1191	sigma factor activity
GYO_1880	COG1191	sigma factor activity
GYO_1881	COG1119	ATPase activity
GYO_1882	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GYO_1883	COG1873	PFAM PRC-barrel domain
GYO_1886	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GYO_1887	COG1799	cell septum assembly
GYO_1888	COG0762	integral membrane protein
GYO_1889	COG2302	S4 RNA-binding domain
GYO_1890	COG3599	regulation of cell shape
GYO_1892	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GYO_1893	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GYO_1894	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GYO_1895	COG0564	pseudouridine synthase activity
GYO_1896	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GYO_1897	COG2233	PERMEase
GYO_1898	COG0540	Belongs to the ATCase OTCase family
GYO_1899	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GYO_1900	COG0505	Belongs to the CarA family
GYO_1901	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GYO_1902	COG0543	2 iron, 2 sulfur cluster binding
GYO_1903	COG0167	dihydroorotate dehydrogenase activity
GYO_1904	COG0284	orotidine-5'-phosphate decarboxylase activity
GYO_1905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GYO_1906	COG0175	sulfate reduction
GYO_1907	COG0306	phosphate transporter
GYO_1908	COG2046	Belongs to the sulfate adenylyltransferase family
GYO_1909	COG0529	Catalyzes the synthesis of activated sulfate
GYO_1910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GYO_1911	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GYO_1912	COG1648	precorrin-2 dehydrogenase activity
GYO_1914	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GYO_1915	COG1561	YicC-like family, N-terminal region
GYO_1916	COG2052	Domain of unknown function (DUF370)
GYO_1917	COG0194	GDP metabolic process
GYO_1918	COG1758	RNA polymerase activity
GYO_1919	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GYO_1921	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GYO_1922	COG0242	peptide deformylase activity
GYO_1923	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GYO_1925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GYO_1925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYO_1926	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GYO_1927	COG0631	protein serine/threonine phosphatase activity
GYO_1928	COG2815	serine threonine protein kinase
GYO_1928	COG0515	serine threonine protein kinase
GYO_1929	COG1162	GTPase activity
GYO_1930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GYO_1931	COG1564	THIamine pyrophosphokinase
GYO_1932	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GYO_1933	COG1302	Protein conserved in bacteria
GYO_1934	COG1461	Dihydroxyacetone kinase
GYO_1935	COG1760	l-serine dehydratase
GYO_1936	COG1760	l-serine dehydratase
GYO_1937	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GYO_1938	COG1349	DNA-binding transcription factor activity
GYO_1938	COG2050	protein possibly involved in aromatic compounds catabolism
GYO_1939	COG0416	fatty acid biosynthetic process
GYO_1940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GYO_1941	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_1942	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYO_1943	COG0571	ribonuclease III activity
GYO_1944	COG1196	nuclear chromosome segregation
GYO_1945	COG0552	protein localization to endoplasmic reticulum
GYO_1947	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GYO_1948	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GYO_1949	COG0228	four-way junction DNA binding
GYO_1950	COG1837	Belongs to the UPF0109 family
GYO_1952	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GYO_1953	COG0336	Belongs to the RNA methyltransferase TrmD family
GYO_1954	COG0335	large ribosomal subunit rRNA binding
GYO_1956	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GYO_1960	COG2257	FlhB HrpN YscU SpaS Family
GYO_1961	COG0045	succinate-CoA ligase (ADP-forming) activity
GYO_1962	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GYO_1964	COG0758	DNA mediated transformation
GYO_1966	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GYO_1967	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GYO_1968	COG4974	Belongs to the 'phage' integrase family
GYO_1969	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GYO_1970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GYO_1971	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GYO_1972	COG1815	bacterial-type flagellum-dependent cell motility
GYO_1973	COG1558	bacterial-type flagellum-dependent cell motility
GYO_1974	COG1677	Flagellar hook-basal body complex protein FliE
GYO_1975	COG1766	The M ring may be actively involved in energy transduction
GYO_1976	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GYO_1977	COG1317	bacterial-type flagellum organization
GYO_1978	COG1157	protein secretion by the type III secretion system
GYO_1979	COG2882	bacterial-type flagellum organization
GYO_1980	COG3334	PFAM MgtE intracellular
GYO_1981	COG3144	bacterial-type flagellum assembly
GYO_1982	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GYO_1983	COG4786	Flagellar basal body rod
GYO_1984	COG1582	Flagellar protein (FlbD)
GYO_1985	COG1580	Controls the rotational direction of flagella during chemotaxis
GYO_1986	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GYO_1987	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GYO_1987	COG1776	CheC inhibitor of MCP methylation
GYO_1988	COG2201	protein-glutamate methylesterase activity
GYO_1989	COG3190	flagellar
GYO_1990	COG1338	Plays a role in the flagellum-specific transport system
GYO_1991	COG1987	bacterial-type flagellum assembly
GYO_1992	COG1684	flagellar biosynthetic protein fliR
GYO_1993	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GYO_1994	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GYO_1995	COG1419	protein localization to endoplasmic reticulum
GYO_1996	COG0455	bacterial-type flagellum organization
GYO_1997	COG2201	protein-glutamate methylesterase activity
GYO_1998	COG2198	Histidine kinase
GYO_1998	COG0643	Histidine kinase
GYO_1999	COG0835	chemotaxis
GYO_2000	COG1776	CheC inhibitor of MCP methylation
GYO_2001	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GYO_2002	COG1191	sigma factor activity
GYO_2004	COG0052	Belongs to the universal ribosomal protein uS2 family
GYO_2005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GYO_2006	COG0528	UMP kinase activity
GYO_2007	COG0233	cytoplasmic translational termination
GYO_2008	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GYO_2009	COG4589	Belongs to the CDS family
GYO_2010	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GYO_2011	COG0750	zinc metalloprotease
GYO_2012	COG0442	prolyl-tRNA aminoacylation
GYO_2013	COG2176	DNA-directed DNA polymerase activity
GYO_2014	COG0779	Required for maturation of 30S ribosomal subunits
GYO_2015	COG0195	Participates in both transcription termination and antitermination
GYO_2016	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GYO_2017	COG1358	cellular component organization or biogenesis
GYO_2019	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GYO_2020	COG1550	Protein conserved in bacteria
GYO_2021	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GYO_2023	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GYO_2024	COG0196	riboflavin kinase activity
GYO_2025	COG1185	polyribonucleotide nucleotidyltransferase activity
GYO_2026	COG0726	polysaccharide deacetylase
GYO_2027	COG0612	Peptidase, M16
GYO_2028	COG1873	PFAM PRC-barrel domain
GYO_2029	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GYO_2030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GYO_2031	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GYO_2032	COG0527	aspartate kinase activity
GYO_2033	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYO_2034	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GYO_2035	COG0740	serine-type endopeptidase activity
GYO_2037	COG4980	gas vesicle protein
GYO_2037	COG1674	ftsk spoiiie
GYO_2038	COG2188	Transcriptional regulator
GYO_2039	COG2814	Major facilitator Superfamily
GYO_2040	COG0612	Peptidase, M16
GYO_2041	COG0612	Peptidase, M16
GYO_2042	COG0300	oxidoreductase activity
GYO_2045	COG1426	Protein conserved in bacteria
GYO_2046	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GYO_2047	COG1058	Belongs to the CinA family
GYO_2047	COG1546	Belongs to the CinA family
GYO_2048	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GYO_2049	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GYO_2050	COG1418	mRNA catabolic process
GYO_2051	COG1692	metallophosphoesterase
GYO_2052	COG2359	stage V sporulation protein S
GYO_2054	COG1063	alcohol dehydrogenase
GYO_2055	COG0156	8-amino-7-oxononanoate synthase activity
GYO_2056	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYO_2057	COG4550	Control of competence regulator ComK, YlbF/YmcA
GYO_2060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GYO_2063	COG3226	Transcriptional regulator
GYO_2064	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_2065	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GYO_2066	COG3321	synthase
GYO_2067	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GYO_2067	COG2070	2-Nitropropane dioxygenase
GYO_2068	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYO_2069	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GYO_2070	COG3425	synthase
GYO_2071	COG1024	Enoyl-CoA hydratase
GYO_2072	COG1024	Enoyl-CoA hydratase
GYO_2073	COG0318	PFAM AMP-dependent synthetase and ligase
GYO_2073	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GYO_2073	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_2073	COG0300	oxidoreductase activity
GYO_2073	COG3321	synthase
GYO_2074	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYO_2074	COG0300	oxidoreductase activity
GYO_2074	COG4221	oxidoreductase activity
GYO_2074	COG3321	synthase
GYO_2075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYO_2075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYO_2075	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_2075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GYO_2075	COG3321	synthase
GYO_2076	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GYO_2076	COG4221	oxidoreductase activity
GYO_2076	COG3321	synthase
GYO_2076	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_2077	COG3321	synthase
GYO_2077	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYO_2077	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GYO_2077	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GYO_2078	COG2124	cytochrome p450
GYO_2080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_2082	COG1404	Belongs to the peptidase S8 family
GYO_2085	COG4195	phage-related replication protein
GYO_2086	COG1764	response to oxidative stress
GYO_2091	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GYO_2092	COG1923	regulation of RNA biosynthetic process
GYO_2096	COG1780	Probably involved in ribonucleotide reductase function
GYO_2097	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYO_2098	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYO_2099	COG4112	unkown
GYO_2100	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYO_2102	COG0464	growth
GYO_2103	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GYO_2104	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GYO_2105	COG0789	Transcriptional regulator
GYO_2106	COG0174	glutamine synthetase
GYO_2111	COG2211	Major facilitator Superfamily
GYO_2112	COG3507	Belongs to the glycosyl hydrolase 43 family
GYO_2115	COG1070	Carbohydrate kinase
GYO_2117	COG1525	nuclease
GYO_2119	COG2814	Major facilitator Superfamily
GYO_2120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GYO_2124	COG0756	dUTP diphosphatase activity
GYO_2135	COG3832	glyoxalase III activity
GYO_2138	COG2059	Chromate
GYO_2139	COG0697	spore germination
GYO_2140	COG0531	amino acid
GYO_2147	COG4195	phage-related replication protein
GYO_2150	COG0346	lactoylglutathione lyase activity
GYO_2152	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GYO_2153	COG1388	LysM domain
GYO_2154	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GYO_2155	COG4224	UPF0291 protein
GYO_2156	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GYO_2159	COG3763	UPF0154 protein
GYO_2161	COG0785	Cytochrome C biogenesis protein
GYO_2162	COG2201	protein-glutamate methylesterase activity
GYO_2163	COG4846	Membrane protein involved in cytochrome C biogenesis
GYO_2165	COG0071	Belongs to the small heat shock protein (HSP20) family
GYO_2168	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GYO_2169	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_2173	COG0824	Thioesterase
GYO_2175	COG4841	protein insertion into membrane
GYO_2176	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GYO_2177	COG1832	CoA-binding protein
GYO_2178	COG0187	DNA topoisomerase II activity
GYO_2179	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GYO_2182	COG1115	amino acid carrier protein
GYO_2183	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GYO_2185	COG2246	polysaccharide biosynthetic process
GYO_2186	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GYO_2187	COG0586	Pfam SNARE associated Golgi protein
GYO_2188	COG2404	hydrolase activity, acting on ester bonds
GYO_2189	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GYO_2190	COG1024	Enoyl-CoA hydratase
GYO_2191	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GYO_2192	COG0511	ligase activity, forming carbon-carbon bonds
GYO_2193	COG0439	Biotin carboxylase
GYO_2194	COG0318	PFAM AMP-dependent synthetase and ligase
GYO_2195	COG1960	acyl-CoA dehydrogenase activity
GYO_2198	COG1649	PFAM Uncharacterised BCR, COG1649
GYO_2204	COG2027	D-alanyl-D-alanine carboxypeptidase
GYO_2205	COG2017	converts alpha-aldose to the beta-anomer
GYO_2206	COG0534	Mate efflux family protein
GYO_2209	COG0582	viral genome integration into host DNA
GYO_2211	COG0166	Belongs to the GPI family
GYO_2212	COG0405	Gamma-glutamyltransferase
GYO_2213	COG0583	DNA-binding transcription factor activity
GYO_2214	COG0604	alcohol dehydrogenase
GYO_2215	COG0493	'glutamate synthase
GYO_2216	COG0070	glutamate synthase
GYO_2216	COG0069	glutamate synthase activity
GYO_2216	COG0067	glutamate synthase
GYO_2217	COG0583	DNA-binding transcription factor activity
GYO_2218	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GYO_2223	COG0300	oxidoreductase activity
GYO_2224	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GYO_2230	COG1131	(ABC) transporter
GYO_2232	COG2814	Major facilitator Superfamily
GYO_2233	COG1070	Carbohydrate kinase
GYO_2234	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GYO_2235	COG0243	molybdopterin cofactor binding
GYO_2241	COG5278	phosphoserine phosphatase activity
GYO_2241	COG0840	transmembrane signaling receptor activity
GYO_2242	COG2368	4-hydroxyphenylacetate
GYO_2243	COG4305	rare lipoprotein A
GYO_2244	COG3619	membrane
GYO_2246	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_2249	COG2135	peptidase activity
GYO_2251	COG2140	Oxalate decarboxylase
GYO_2256	COG2720	vancomycin resistance protein
GYO_2258	COG3655	Transcriptional regulator
GYO_2259	COG3739	integral membrane protein
GYO_2260	COG0583	DNA-binding transcription factor activity
GYO_2261	COG0697	spore germination
GYO_2267	COG0693	protein deglycase activity
GYO_2268	COG2367	Beta-lactamase
GYO_2269	COG4282	regulation of fungal-type cell wall biogenesis
GYO_2271	COG3397	chitin binding
GYO_2273	COG2318	DinB family
GYO_2274	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYO_2275	COG0726	polysaccharide deacetylase
GYO_2279	COG2273	Hydrolase Family 16
GYO_2281	COG2124	cytochrome p450
GYO_2286	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GYO_2287	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GYO_2288	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYO_2294	COG0110	maltose O-acetyltransferase activity
GYO_2298	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYO_2299	COG4282	regulation of fungal-type cell wall biogenesis
GYO_2300	COG1231	oxidoreductase activity
GYO_2302	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYO_2303	COG2207	Transcriptional regulator
GYO_2303	COG0662	Cupin 2, conserved barrel domain protein
GYO_2306	COG1309	transcriptional regulator
GYO_2307	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_2308	COG3708	Transcriptional regulator
GYO_2309	COG2378	regulation of single-species biofilm formation
GYO_2311	COG0640	Transcriptional regulator
GYO_2312	COG0741	lytic transglycosylase activity
GYO_2313	COG2322	membrane
GYO_2318	COG3239	Fatty acid desaturase
GYO_2320	COG4585	Histidine kinase
GYO_2321	COG2197	response regulator
GYO_2322	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYO_2325	COG3584	3D domain protein
GYO_2325	COG1388	LysM domain
GYO_2326	COG0514	ATP-dependent DNA helicase (RecQ)
GYO_2327	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GYO_2328	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GYO_2333	COG1012	belongs to the aldehyde dehydrogenase family
GYO_2334	COG1657	PFAM Prenyltransferase squalene oxidase
GYO_2335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GYO_2336	COG0733	neurotransmitter:sodium symporter activity
GYO_2337	COG0385	Bile acid
GYO_2338	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYO_2339	COG0567	Dehydrogenase, E1 component
GYO_2340	COG4548	von Willebrand factor, type A
GYO_2341	COG0714	Associated with various cellular activities
GYO_2342	COG2032	superoxide dismutase activity
GYO_2343	COG0791	NLP P60 protein
GYO_2343	COG1388	LysM domain
GYO_2344	COG1819	glycosyl
GYO_2345	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GYO_2346	COG0534	Mate efflux family protein
GYO_2347	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_2348	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GYO_2349	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GYO_2351	COG2962	Rard protein
GYO_2354	COG2610	gluconate transmembrane transporter activity
GYO_2356	COG1942	4-Oxalocrotonate Tautomerase
GYO_2358	COG1733	regulation of RNA biosynthetic process
GYO_2359	COG0778	Nitroreductase
GYO_2360	COG0400	carboxylic ester hydrolase activity
GYO_2361	COG0346	lactoylglutathione lyase activity
GYO_2363	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYO_2364	COG3409	Peptidoglycan-binding domain 1 protein
GYO_2364	COG0793	Belongs to the peptidase S41A family
GYO_2365	COG2226	methyltransferase
GYO_2367	COG1876	peptidase activity
GYO_2368	COG0813	purine-nucleoside phosphorylase activity
GYO_2371	COG0671	phosphoesterase, PA-phosphatase related
GYO_2375	COG4479	Belongs to the UPF0346 family
GYO_2377	COG1509	lysine 2,3-aminomutase activity
GYO_2378	COG0456	acetyltransferase
GYO_2379	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GYO_2380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GYO_2381	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GYO_2382	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GYO_2384	COG0456	acetyltransferase
GYO_2385	COG0463	Glycosyl transferase, family 2
GYO_2388	COG4641	Protein conserved in bacteria
GYO_2389	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
GYO_2390	COG1086	Polysaccharide biosynthesis protein
GYO_2392	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYO_2393	COG1846	Transcriptional regulator
GYO_2394	COG0534	Mate efflux family protein
GYO_2396	COG4698	Protein conserved in bacteria
GYO_2397	COG2755	lipolytic protein G-D-S-L family
GYO_2398	COG1999	signal sequence binding
GYO_2400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GYO_2401	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GYO_2402	COG1272	protein, Hemolysin III
GYO_2403	COG0204	Acyl-transferase
GYO_2404	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GYO_2406	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GYO_2408	COG2136	Putative SAM-dependent methyltransferase
GYO_2408	COG2521	methyltransferase
GYO_2410	COG0129	dihydroxy-acid dehydratase activity
GYO_2411	COG1413	lyase activity
GYO_2412	COG1418	mRNA catabolic process
GYO_2413	COG0386	Belongs to the glutathione peroxidase family
GYO_2414	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GYO_2415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GYO_2417	COG1278	Cold shock
GYO_2421	COG0328	RNA-DNA hybrid ribonuclease activity
GYO_2422	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GYO_2423	COG0328	RNA-DNA hybrid ribonuclease activity
GYO_2425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GYO_2428	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GYO_2429	COG1755	Isoprenylcysteine carboxyl methyltransferase
GYO_2430	COG3424	synthase
GYO_2431	COG2233	PERMEase
GYO_2432	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GYO_2433	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GYO_2435	COG0800	Aldolase
GYO_2436	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYO_2437	COG1609	Transcriptional regulator
GYO_2439	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GYO_2440	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_2441	COG1199	ATP-dependent helicase activity
GYO_2443	COG0116	Belongs to the methyltransferase superfamily
GYO_2445	COG4474	Belongs to the UPF0398 family
GYO_2447	COG3359	exonuclease
GYO_2448	COG1111	helicase
GYO_2448	COG1205	dead DEAH box helicase
GYO_2449	COG2190	(PTS) system
GYO_2450	COG0071	Belongs to the small heat shock protein (HSP20) family
GYO_2457	COG3331	DNA recombination
GYO_2458	COG4499	WXG100 protein secretion system (Wss), protein YukC
GYO_2458	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYO_2460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GYO_2461	COG3935	DnaD domain protein
GYO_2462	COG0017	Asparaginyl-tRNA synthetase
GYO_2463	COG0436	Aminotransferase
GYO_2464	COG5353	protein conserved in bacteria
GYO_2466	COG1199	ATP-dependent helicase activity
GYO_2466	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GYO_2467	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GYO_2468	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GYO_2469	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GYO_2472	COG0617	tRNA 3'-terminal CCA addition
GYO_2473	COG0438	transferase activity, transferring glycosyl groups
GYO_2474	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GYO_2475	COG1803	Methylglyoxal synthase
GYO_2476	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GYO_2477	COG1694	Mazg nucleotide pyrophosphohydrolase
GYO_2478	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYO_2480	COG4347	Protein of unknown function (DUF1405)
GYO_2481	COG2010	Cytochrome c
GYO_2481	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GYO_2482	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GYO_2483	COG0723	plastoquinol--plastocyanin reductase activity
GYO_2485	COG5582	Belongs to the UPF0302 family
GYO_2486	COG0457	Tetratricopeptide repeat
GYO_2487	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GYO_2488	COG0287	Prephenate dehydrogenase
GYO_2489	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GYO_2490	COG0159	tryptophan synthase activity
GYO_2491	COG0133	tryptophan synthase activity
GYO_2492	COG0135	phosphoribosylanthranilate isomerase activity
GYO_2494	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYO_2495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GYO_2496	COG4401	Chorismate mutase type I
GYO_2497	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GYO_2498	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GYO_2499	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GYO_2501	COG0105	UTP biosynthetic process
GYO_2502	COG0142	geranyltranstransferase activity
GYO_2503	COG2226	methyltransferase
GYO_2504	COG0142	geranyltranstransferase activity
GYO_2506	COG0302	gtp cyclohydrolase
GYO_2507	COG0776	regulation of translation
GYO_2512	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GYO_2513	COG1160	GTP binding
GYO_2518	COG1304	FMN binding
GYO_2519	COG0539	negative regulation of cytoplasmic translation
GYO_2520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GYO_2522	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GYO_2523	COG2959	enzyme of heme biosynthesis
GYO_2524	COG3773	Cell wall hydrolase
GYO_2524	COG3409	Peptidoglycan-binding domain 1 protein
GYO_2526	COG2339	peptidase activity
GYO_2527	COG0492	ferredoxin-NADP+ reductase activity
GYO_2528	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYO_2529	COG4862	establishment of competence for transformation
GYO_2530	COG1408	metallophosphoesterase
GYO_2532	COG1388	LysM domain
GYO_2533	COG1266	CAAX protease self-immunity
GYO_2534	COG0514	ATP-dependent DNA helicase (RecQ)
GYO_2535	COG4955	Helix-turn-helix domain
GYO_2536	COG1141	Ferredoxin
GYO_2537	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GYO_2539	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GYO_2540	COG0710	3-dehydroquinate dehydratase activity
GYO_2542	COG1595	DNA-templated transcription, initiation
GYO_2543	COG5002	protein histidine kinase activity
GYO_2544	COG0745	RESPONSE REGULATOR receiver
GYO_2545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GYO_2546	COG1333	cytochrome c biogenesis protein
GYO_2547	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_2549	COG1187	pseudouridine synthase activity
GYO_2551	COG2715	membrane protein required for spore maturation
GYO_2552	COG1686	Belongs to the peptidase S11 family
GYO_2554	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GYO_2555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GYO_2556	COG1547	Domain of unknown function (DUF309)
GYO_2557	COG0456	acetyltransferase
GYO_2558	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GYO_2559	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYO_2559	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYO_2560	COG0307	riboflavin synthase, alpha
GYO_2561	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYO_2561	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYO_2564	COG0681	Belongs to the peptidase S26 family
GYO_2567	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
GYO_2569	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GYO_2570	COG4086	secreted protein
GYO_2571	COG0019	diaminopimelate decarboxylase activity
GYO_2575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYO_2579	COG1191	sigma factor activity
GYO_2580	COG2172	sigma factor antagonist activity
GYO_2581	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_2584	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GYO_2585	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GYO_2586	COG4974	Belongs to the 'phage' integrase family
GYO_2588	COG0735	belongs to the Fur family
GYO_2589	COG1300	Membrane
GYO_2591	COG0281	malic enzyme
GYO_2592	COG1757	Na H antiporter
GYO_2593	COG1027	Aspartate ammonia-lyase
GYO_2594	COG0252	asparaginase activity
GYO_2595	COG1396	sequence-specific DNA binding
GYO_2596	COG1379	DNA repair
GYO_2597	COG0494	nUDIX hydrolase
GYO_2599	COG0667	Aldo Keto reductase
GYO_2601	COG1073	alpha beta
GYO_2602	COG0772	Belongs to the SEDS family
GYO_2603	COG0772	Belongs to the SEDS family
GYO_2604	COG3339	Conserved Protein
GYO_2606	COG4918	Iron-sulphur cluster biosynthesis
GYO_2607	COG0456	acetyltransferase
GYO_2607	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GYO_2608	COG2329	Antibiotic biosynthesis monooxygenase
GYO_2609	COG0456	acetyltransferase
GYO_2611	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYO_2616	COG2211	Major facilitator Superfamily
GYO_2618	COG0346	lactoylglutathione lyase activity
GYO_2619	COG1072	(Pantothenic acid kinase))
GYO_2620	COG3048	D-serine ammonia-lyase activity
GYO_2621	COG0300	oxidoreductase activity
GYO_2622	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_2623	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYO_2624	COG4187	Peptidase family M20/M25/M40
GYO_2625	COG1902	pentaerythritol trinitrate reductase activity
GYO_2626	COG0596	Alpha beta hydrolase
GYO_2628	COG1234	tRNA 3'-trailer cleavage
GYO_2630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GYO_2631	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GYO_2632	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYO_2634	COG0706	membrane insertase activity
GYO_2635	COG3361	conserved protein (COG2071)
GYO_2636	COG2195	Cleaves the N-terminal amino acid of tripeptides
GYO_2637	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GYO_2638	COG0346	lactoylglutathione lyase activity
GYO_2639	COG1376	ErfK ybiS ycfS ynhG family protein
GYO_2640	COG4129	membrane
GYO_2641	COG1126	abc transporter atp-binding protein
GYO_2642	COG0765	amino acid transport
GYO_2643	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GYO_2645	COG1597	lipid kinase activity
GYO_2646	COG2814	Major facilitator Superfamily
GYO_2647	COG4978	Transcriptional regulator
GYO_2647	COG0789	Transcriptional regulator
GYO_2648	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYO_2649	COG0022	dehydrogenase e1 component
GYO_2650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GYO_2651	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYO_2652	COG3426	butyrate kinase activity
GYO_2653	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYO_2654	COG0280	phosphate acetyltransferase
GYO_2655	COG3290	protein histidine kinase activity
GYO_2655	COG3829	transcription factor binding
GYO_2657	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GYO_2658	COG2079	MmgE PrpD family protein
GYO_2659	COG0372	Belongs to the citrate synthase family
GYO_2660	COG1960	acyl-CoA dehydrogenase activity
GYO_2661	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYO_2662	COG0183	Belongs to the thiolase family
GYO_2664	COG0584	glycerophosphoryl diester phosphodiesterase
GYO_2665	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYO_2668	COG1902	pentaerythritol trinitrate reductase activity
GYO_2673	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GYO_2678	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GYO_2679	COG0745	RESPONSE REGULATOR receiver
GYO_2681	COG0750	zinc metalloprotease
GYO_2682	COG0497	DNA recombination
GYO_2684	COG1438	arginine binding
GYO_2685	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GYO_2686	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GYO_2688	COG0142	geranyltranstransferase activity
GYO_2689	COG1722	exodeoxyribonuclease VII activity
GYO_2690	COG1570	exodeoxyribonuclease VII activity
GYO_2691	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GYO_2692	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYO_2693	COG1302	Protein conserved in bacteria
GYO_2694	COG0439	Biotin carboxylase
GYO_2695	COG0511	ligase activity, forming carbon-carbon bonds
GYO_2703	COG3854	ATPases associated with a variety of cellular activities
GYO_2705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GYO_2706	COG0006	proline dipeptidase activity
GYO_2707	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GYO_2709	COG3872	metal-dependent enzyme
GYO_2711	COG1752	Esterase of the alpha-beta hydrolase superfamily
GYO_2712	COG1321	iron dependent repressor
GYO_2713	COG0095	Lipoate-protein ligase
GYO_2714	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYO_2715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GYO_2716	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GYO_2717	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GYO_2718	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GYO_2721	COG1396	sequence-specific DNA binding
GYO_2723	COG0681	Belongs to the peptidase S26 family
GYO_2728	COG4940	Competence protein ComGF
GYO_2732	COG4970	Tfp pilus assembly protein FimT
GYO_2733	COG4537	Required for transformation and DNA binding
GYO_2734	COG1459	type II secretion system
GYO_2735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GYO_2736	COG0517	IMP dehydrogenase activity
GYO_2737	COG0598	Magnesium transport protein CorA
GYO_2738	COG1253	flavin adenine dinucleotide binding
GYO_2739	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_2741	COG1393	Belongs to the ArsC family
GYO_2743	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_2745	COG0011	TIGRFAM Protein of
GYO_2747	COG2866	Carboxypeptidase
GYO_2748	COG1368	sulfuric ester hydrolase activity
GYO_2749	COG1940	carbohydrate kinase activity
GYO_2750	COG4483	Protein conserved in bacteria
GYO_2752	COG0705	Rhomboid family
GYO_2752	COG0457	Tetratricopeptide repeat
GYO_2755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GYO_2756	COG0438	transferase activity, transferring glycosyl groups
GYO_2759	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GYO_2760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GYO_2761	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GYO_2762	COG0581	inorganic phosphate transmembrane transporter activity
GYO_2763	COG0573	inorganic phosphate transmembrane transporter activity
GYO_2764	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GYO_2766	COG0477	Major facilitator Superfamily
GYO_2767	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GYO_2768	COG2839	Protein conserved in bacteria
GYO_2769	COG5521	maltodextrose utilization protein MalA
GYO_2770	COG1388	LysM domain
GYO_2771	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GYO_2772	COG4709	membrane
GYO_2773	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GYO_2774	COG0735	belongs to the Fur family
GYO_2775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYO_2777	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GYO_2778	COG0513	Belongs to the DEAD box helicase family
GYO_2780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GYO_2781	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GYO_2782	COG2384	SAM-dependent methyltransferase
GYO_2783	COG2010	Cytochrome c
GYO_2785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GYO_2786	COG0358	DNA primase activity
GYO_2787	COG1671	Belongs to the UPF0178 family
GYO_2788	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GYO_2789	COG0517	IMP dehydrogenase activity
GYO_2790	COG0751	glycine-tRNA ligase activity
GYO_2791	COG0752	glycyl-tRNA synthetase alpha subunit
GYO_2792	COG1381	Involved in DNA repair and RecF pathway recombination
GYO_2794	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GYO_2795	COG0295	cytidine deaminase activity
GYO_2797	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GYO_2798	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GYO_2799	COG1480	7TM receptor with intracellular HD hydrolase
GYO_2801	COG1702	phosphate starvation-inducible protein PhoH
GYO_2806	COG4864	UPF0365 protein
GYO_2807	COG1030	water channel activity
GYO_2808	COG1610	YqeY-like protein
GYO_2809	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GYO_2810	COG1283	sodium-dependent phosphate transmembrane transporter activity
GYO_2811	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYO_2812	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GYO_2813	COG2264	protein methyltransferase activity
GYO_2814	COG0484	heat shock protein binding
GYO_2816	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GYO_2817	COG1420	regulation of RNA biosynthetic process
GYO_2818	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYO_2819	COG0481	GTPase activity
GYO_2821	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYO_2822	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GYO_2823	COG0268	Binds directly to 16S ribosomal RNA
GYO_2824	COG1466	dna polymerase III delta subunit
GYO_2827	COG0658	competence protein
GYO_2827	COG2333	competence protein COMEC
GYO_2828	COG2131	deaminase
GYO_2829	COG1555	photosystem II stabilization
GYO_2829	COG1596	polysaccharide export
GYO_2830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYO_2831	COG2226	methyltransferase
GYO_2832	COG0799	negative regulation of ribosome biogenesis
GYO_2833	COG1713	HD superfamily hydrolase involved in NAD metabolism
GYO_2834	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GYO_2835	COG1534	Rna-binding protein
GYO_2836	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GYO_2837	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GYO_2838	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GYO_2840	COG2755	lipolytic protein G-D-S-L family
GYO_2841	COG5632	N-Acetylmuramoyl-L-alanine amidase
GYO_2841	COG3409	Peptidoglycan-binding domain 1 protein
GYO_2842	COG0398	Pfam SNARE associated Golgi protein
GYO_2843	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GYO_2845	COG3209	COG3209 Rhs family protein
GYO_2848	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GYO_2850	COG0251	oxidation-reduction process
GYO_2852	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GYO_2855	COG0457	Tetratricopeptide repeat
GYO_2857	COG5444	nuclease activity
GYO_2858	COG5444	nuclease activity
GYO_2866	COG0730	response to heat
GYO_2867	COG0425	Belongs to the sulfur carrier protein TusA family
GYO_2868	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYO_2868	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_2870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYO_2870	COG0425	Belongs to the sulfur carrier protein TusA family
GYO_2872	COG2210	Belongs to the sulfur carrier protein TusA family
GYO_2877	COG2197	response regulator
GYO_2878	COG4585	Histidine kinase
GYO_2879	COG0730	response to heat
GYO_2881	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GYO_2884	COG3711	transcriptional antiterminator
GYO_2885	COG2723	6-phospho-beta-galactosidase activity
GYO_2886	COG1263	PTS System
GYO_2886	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_2886	COG2190	(PTS) system
GYO_2887	COG2217	Heavy metal translocating P-type atpase
GYO_2888	COG2608	mercury ion transmembrane transporter activity
GYO_2889	COG1937	Protein conserved in bacteria
GYO_2892	COG2856	Zn peptidase
GYO_2896	COG1733	regulation of RNA biosynthetic process
GYO_2900	COG2732	(Barnase) inhibitor
GYO_2903	COG4978	Transcriptional regulator
GYO_2903	COG0789	Transcriptional regulator
GYO_2904	COG2814	Major facilitator Superfamily
GYO_2905	COG0456	acetyltransferase
GYO_2906	COG1253	flavin adenine dinucleotide binding
GYO_2909	COG4193	domain, Protein
GYO_2913	COG4978	Transcriptional regulator
GYO_2913	COG0789	Transcriptional regulator
GYO_2915	COG2315	Protein conserved in bacteria
GYO_2918	COG3443	Belongs to the bacterial solute-binding protein 9 family
GYO_2919	COG1595	DNA-templated transcription, initiation
GYO_2920	COG0667	Aldo Keto reductase
GYO_2921	COG3409	Peptidoglycan-binding domain 1 protein
GYO_2922	COG5566	PFAM Mor transcription activator
GYO_2923	COG0596	Alpha beta hydrolase
GYO_2924	COG4991	sh3 domain protein
GYO_2925	COG4991	sh3 domain protein
GYO_2927	COG5577	PFAM Coat F domain
GYO_2928	COG1063	alcohol dehydrogenase
GYO_2930	COG5577	PFAM Coat F domain
GYO_2931	COG2207	Transcriptional regulator
GYO_2933	COG0789	Transcriptional regulator
GYO_2934	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GYO_2935	COG1064	alcohol dehydrogenase
GYO_2936	COG0693	protein deglycase activity
GYO_2937	COG1621	beta-fructofuranosidase activity
GYO_2938	COG3716	PTS system mannose fructose sorbose family IID component
GYO_2939	COG3715	PTS system
GYO_2940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_2941	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_2942	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GYO_2942	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GYO_2946	COG1113	amino acid transport
GYO_2947	COG1280	lysine exporter protein (LysE YggA)
GYO_2948	COG1378	Sugar-specific transcriptional regulator TrmB
GYO_2949	COG1595	DNA-templated transcription, initiation
GYO_2951	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GYO_2951	COG2755	lipolytic protein G-D-S-L family
GYO_2953	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GYO_2953	COG2124	cytochrome p450
GYO_2954	COG1309	transcriptional regulator
GYO_2955	COG2226	methyltransferase
GYO_2959	COG2116	formate transmembrane transporter activity
GYO_2961	COG5609	conserved protein (DUF2294)
GYO_2962	COG3383	formate dehydrogenase (NAD+) activity
GYO_2963	COG2427	Protein of unknown function (DUF1641)
GYO_2965	COG0626	cystathionine gamma-synthase activity
GYO_2966	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GYO_2967	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GYO_2968	COG2226	methyltransferase
GYO_2971	COG0768	penicillin binding
GYO_2972	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GYO_2973	COG0572	uridine kinase
GYO_2977	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GYO_2979	COG3906	Belongs to the UPF0473 family
GYO_2980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GYO_2981	COG4472	Bacterial protein of unknown function (DUF965)
GYO_2982	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GYO_2983	COG0628	permease
GYO_2986	COG3881	PFAM PRC-barrel domain
GYO_2987	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GYO_2988	COG0457	Tetratricopeptide repeat
GYO_2989	COG0482	sulfurtransferase activity
GYO_2990	COG1104	cysteine desulfurase activity
GYO_2991	COG1959	2 iron, 2 sulfur cluster binding
GYO_2992	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GYO_2993	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GYO_2995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GYO_2996	COG0124	histidyl-tRNA synthetase
GYO_2998	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYO_2998	COG3103	Sh3 type 3 domain protein
GYO_2998	COG4991	sh3 domain protein
GYO_2999	COG1490	D-aminoacyl-tRNA deacylase activity
GYO_3000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GYO_3001	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GYO_3002	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GYO_3002	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GYO_3003	COG5416	Lipopolysaccharide assembly protein A domain
GYO_3004	COG0490	domain, Protein
GYO_3005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GYO_3005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GYO_3007	COG2244	polysaccharide biosynthetic process
GYO_3008	COG2323	membrane
GYO_3010	COG1862	Preprotein translocase
GYO_3011	COG0343	queuine tRNA-ribosyltransferase activity
GYO_3012	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GYO_3014	COG2255	four-way junction helicase activity
GYO_3015	COG0632	four-way junction helicase activity
GYO_3017	COG2814	Major facilitator Superfamily
GYO_3018	COG0673	inositol 2-dehydrogenase activity
GYO_3019	COG2112	serine threonine protein kinase
GYO_3021	COG1115	amino acid carrier protein
GYO_3022	COG0217	transcriptional regulatory protein
GYO_3024	COG1388	LysM domain
GYO_3025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GYO_3026	COG0157	Belongs to the NadC ModD family
GYO_3027	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GYO_3028	COG1104	cysteine desulfurase activity
GYO_3029	COG1827	regulation of RNA biosynthetic process
GYO_3030	COG0077	Prephenate dehydratase
GYO_3031	COG4492	Belongs to the UPF0735 family
GYO_3032	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GYO_3033	COG3290	protein histidine kinase activity
GYO_3035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GYO_3036	COG2868	ribosomal protein
GYO_3037	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GYO_3038	COG1994	Peptidase M50
GYO_3039	COG0739	heme binding
GYO_3041	COG2894	cell division
GYO_3042	COG0850	regulation of cytokinetic process
GYO_3043	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GYO_3044	COG1792	Involved in formation and maintenance of cell shape
GYO_3045	COG1077	Cell shape determining protein MreB Mrl
GYO_3046	COG2003	Belongs to the UPF0758 family
GYO_3047	COG0424	maF-like protein
GYO_3049	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GYO_3051	COG0285	dihydrofolate synthase activity
GYO_3052	COG0525	valine-tRNA ligase activity
GYO_3054	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GYO_3055	COG1388	LysM domain
GYO_3056	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GYO_3057	COG0113	porphobilinogen synthase activity
GYO_3058	COG1587	Uroporphyrinogen-III synthase
GYO_3059	COG0181	hydroxymethylbilane synthase activity
GYO_3060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GYO_3061	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GYO_3063	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GYO_3064	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GYO_3065	COG0470	DNA polymerase III
GYO_3065	COG1067	ATP-dependent peptidase activity
GYO_3066	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GYO_3067	COG0544	peptidyl-prolyl cis-trans isomerase activity
GYO_3068	COG1477	protein flavinylation
GYO_3068	COG0457	Tetratricopeptide repeat
GYO_3070	COG0066	3-isopropylmalate dehydratase activity
GYO_3071	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GYO_3072	COG0473	3-isopropylmalate dehydrogenase activity
GYO_3073	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GYO_3074	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GYO_3075	COG0440	acetolactate synthase activity
GYO_3076	COG0028	Belongs to the TPP enzyme family
GYO_3078	COG0454	-acetyltransferase
GYO_3079	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GYO_3081	COG0622	Phosphoesterase
GYO_3082	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GYO_3083	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GYO_3084	COG5401	PFAM Sporulation and spore germination
GYO_3085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GYO_3086	COG1846	Transcriptional regulator
GYO_3087	COG2197	response regulator
GYO_3088	COG0824	Thioesterase
GYO_3089	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GYO_3090	COG1053	succinate dehydrogenase
GYO_3091	COG2009	succinate dehydrogenase
GYO_3092	COG1719	4-vinyl reductase, 4VR
GYO_3093	COG0527	aspartate kinase activity
GYO_3096	COG0322	excinuclease ABC activity
GYO_3097	COG3118	belongs to the thioredoxin family
GYO_3098	COG3534	alpha-L-arabinofuranosidase
GYO_3099	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GYO_3100	COG2086	electron transfer activity
GYO_3101	COG1024	Enoyl-CoA hydratase
GYO_3102	COG1309	transcriptional regulator
GYO_3103	COG0318	PFAM AMP-dependent synthetase and ligase
GYO_3104	COG3766	membrane
GYO_3105	COG1193	negative regulation of DNA recombination
GYO_3106	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GYO_3106	COG1796	DNA polymerase
GYO_3107	COG1286	toxin biosynthetic process
GYO_3108	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GYO_3109	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GYO_3110	COG0072	phenylalanine-tRNA ligase activity
GYO_3110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYO_3111	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GYO_3112	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYO_3114	COG3835	regulator
GYO_3115	COG0277	FAD linked oxidase domain protein
GYO_3116	COG0247	lactate metabolic process
GYO_3117	COG0346	lactoylglutathione lyase activity
GYO_3118	COG1966	Carbon starvation protein
GYO_3121	COG1695	Transcriptional regulator
GYO_3122	COG3534	alpha-L-arabinofuranosidase
GYO_3123	COG0395	ABC-type sugar transport system, permease component
GYO_3124	COG1175	transmembrane transport
GYO_3125	COG1653	transport
GYO_3126	COG0371	Dehydrogenase
GYO_3127	COG0647	UMP catabolic process
GYO_3128	COG0235	Class ii aldolase
GYO_3129	COG1069	ribulokinase activity
GYO_3130	COG2160	L-arabinose isomerase activity
GYO_3132	COG3507	Belongs to the glycosyl hydrolase 43 family
GYO_3133	COG1363	Peptidase, m42
GYO_3135	COG3326	Membrane
GYO_3136	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GYO_3137	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GYO_3140	COG1346	cytolysis
GYO_3141	COG1380	Effector of murein hydrolase LrgA
GYO_3142	COG3279	Response regulator of the LytR AlgR family
GYO_3143	COG3275	phosphorelay sensor kinase activity
GYO_3145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GYO_3147	COG0398	Pfam SNARE associated Golgi protein
GYO_3148	COG1484	DNA-dependent DNA replication
GYO_3149	COG3611	Membrane attachment protein
GYO_3150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GYO_3151	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GYO_3152	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GYO_3153	COG1733	regulation of RNA biosynthetic process
GYO_3154	COG2814	Major facilitator Superfamily
GYO_3155	COG0656	L-ascorbic acid biosynthetic process
GYO_3156	COG0237	dephospho-CoA kinase activity
GYO_3157	COG1971	Probably functions as a manganese efflux pump
GYO_3158	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GYO_3159	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GYO_3159	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GYO_3161	COG5002	protein histidine kinase activity
GYO_3162	COG0745	RESPONSE REGULATOR receiver
GYO_3164	COG0039	L-malate dehydrogenase activity
GYO_3165	COG0538	isocitrate dehydrogenase activity
GYO_3166	COG0372	Belongs to the citrate synthase family
GYO_3167	COG2707	UPF0756 membrane protein
GYO_3168	COG0628	permease
GYO_3170	COG3030	protein affecting phage T7 exclusion by the F plasmid
GYO_3171	COG0469	pyruvate kinase activity
GYO_3172	COG0205	6-phosphofructokinase activity
GYO_3173	COG0825	malonyl-CoA metabolic process
GYO_3174	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GYO_3175	COG0281	malic enzyme
GYO_3176	COG0587	DNA-directed DNA polymerase activity
GYO_3180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GYO_3183	COG4109	DRTGG domain
GYO_3184	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GYO_3185	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3188	COG0165	Argininosuccinate lyase
GYO_3189	COG0137	argininosuccinate synthase activity
GYO_3190	COG0521	Mo-molybdopterin cofactor biosynthetic process
GYO_3191	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GYO_3193	COG0827	DNA restriction-modification system
GYO_3194	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GYO_3195	COG3874	Sporulation protein YtfJ
GYO_3197	COG1714	RDD family
GYO_3198	COG0616	signal peptide processing
GYO_3200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GYO_3201	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GYO_3202	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GYO_3204	COG0301	tRNA thio-modification
GYO_3205	COG1104	cysteine desulfurase activity
GYO_3206	COG1114	Component of the transport system for branched-chain amino acids
GYO_3207	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GYO_3208	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GYO_3209	COG1309	transcriptional regulator
GYO_3210	COG1956	GAF domain-containing protein
GYO_3211	COG2199	diguanylate cyclase activity
GYO_3211	COG2203	Gaf domain
GYO_3213	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GYO_3215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GYO_3216	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GYO_3217	COG0454	-acetyltransferase
GYO_3218	COG0517	IMP dehydrogenase activity
GYO_3219	COG0123	including yeast histone deacetylase and acetoin utilization protein
GYO_3220	COG1360	Flagellar Motor Protein
GYO_3221	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GYO_3222	COG1609	Transcriptional regulator
GYO_3223	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GYO_3223	COG1605	Chorismate mutase
GYO_3224	COG3118	belongs to the thioredoxin family
GYO_3225	COG4980	gas vesicle protein
GYO_3226	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GYO_3227	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GYO_3228	COG1674	ftsk spoiiie
GYO_3229	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYO_3230	COG4848	Belongs to the UPF0354 family
GYO_3231	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_3234	COG1363	Peptidase, m42
GYO_3235	COG5584	Small secreted protein
GYO_3236	COG0281	malic enzyme
GYO_3237	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_3238	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GYO_3240	COG0510	thiamine kinase activity
GYO_3241	COG1523	belongs to the glycosyl hydrolase 13 family
GYO_3242	COG1597	lipid kinase activity
GYO_3244	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GYO_3245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GYO_3246	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GYO_3248	COG4473	ABC transporter
GYO_3249	COG1131	(ABC) transporter
GYO_3250	COG1349	DNA-binding transcription factor activity
GYO_3251	COG1187	pseudouridine synthase activity
GYO_3252	COG2244	polysaccharide biosynthetic process
GYO_3253	COG2081	HI0933 family
GYO_3255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GYO_3257	COG5578	integral membrane protein
GYO_3258	COG0673	inositol 2-dehydrogenase activity
GYO_3259	COG1653	transport
GYO_3260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GYO_3261	COG4209	transmembrane transport
GYO_3262	COG2207	Transcriptional regulator
GYO_3263	COG1653	transport
GYO_3264	COG0395	ABC-type sugar transport system, permease component
GYO_3266	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYO_3267	COG2124	cytochrome p450
GYO_3268	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GYO_3270	COG0156	8-amino-7-oxononanoate synthase activity
GYO_3271	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GYO_3274	COG1073	alpha beta
GYO_3279	COG1486	melibiose metabolic process
GYO_3281	COG2801	Transposase and inactivated derivatives
GYO_3282	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYO_3283	COG0495	leucyl-tRNA aminoacylation
GYO_3285	COG1366	Belongs to the anti-sigma-factor antagonist family
GYO_3285	COG2202	Pas domain
GYO_3286	COG2814	Major facilitator Superfamily
GYO_3287	COG2433	Pfam Transposase IS66
GYO_3288	COG0577	efflux transmembrane transporter activity
GYO_3289	COG1136	(ABC) transporter
GYO_3290	COG2205	protein histidine kinase activity
GYO_3291	COG0745	RESPONSE REGULATOR receiver
GYO_3292	COG0577	efflux transmembrane transporter activity
GYO_3293	COG1136	(ABC) transporter
GYO_3296	COG1131	(ABC) transporter
GYO_3297	COG1725	Transcriptional regulator
GYO_3300	COG1242	4 iron, 4 sulfur cluster binding
GYO_3301	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GYO_3303	COG2267	carboxylic ester hydrolase activity
GYO_3304	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GYO_3305	COG1113	amino acid transport
GYO_3306	COG0367	asparagine synthase
GYO_3307	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GYO_3308	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GYO_3310	COG1506	peptidase
GYO_3311	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GYO_3312	COG1116	anion transmembrane transporter activity
GYO_3313	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GYO_3314	COG0494	nUDIX hydrolase
GYO_3315	COG4824	toxin secretion phage lysis holin
GYO_3317	COG0783	Belongs to the Dps family
GYO_3320	COG1854	S-ribosylhomocysteine lyase activity
GYO_3321	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GYO_3322	COG0288	reversible hydration of carbon dioxide
GYO_3323	COG0254	rRNA binding
GYO_3325	COG1271	oxidase subunit
GYO_3326	COG1294	oxidase, subunit
GYO_3328	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GYO_3329	COG1321	iron dependent repressor
GYO_3329	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GYO_3330	COG1121	(ABC) transporter
GYO_3331	COG0803	Belongs to the bacterial solute-binding protein 9 family
GYO_3332	COG4948	Mandelate Racemase Muconate Lactonizing
GYO_3333	COG0318	PFAM AMP-dependent synthetase and ligase
GYO_3334	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GYO_3335	COG0596	Alpha beta hydrolase
GYO_3336	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GYO_3337	COG1169	isochorismate synthase
GYO_3339	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GYO_3340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GYO_3341	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GYO_3342	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYO_3343	COG0438	transferase activity, transferring glycosyl groups
GYO_3345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GYO_3346	COG0438	transferase activity, transferring glycosyl groups
GYO_3347	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GYO_3348	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GYO_3349	COG0058	SHG alpha-glucan phosphorylase activity
GYO_3350	COG0297	glycogen (starch) synthase activity
GYO_3351	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GYO_3352	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GYO_3353	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GYO_3377	COG3859	Proton-coupled thiamine transporter YuaJ
GYO_3378	COG1247	-acetyltransferase
GYO_3379	COG2268	Band 7 protein
GYO_3380	COG1585	Membrane protein implicated in regulation of membrane protease activity
GYO_3381	COG2318	DinB family
GYO_3383	COG1454	alcohol dehydrogenase
GYO_3385	COG1510	regulation of RNA biosynthetic process
GYO_3387	COG0569	domain protein
GYO_3388	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GYO_3389	COG4682	membrane
GYO_3390	COG1705	Flagellar rod assembly protein muramidase FlgJ
GYO_3391	COG0477	Major facilitator Superfamily
GYO_3398	COG1968	undecaprenyl-diphosphatase activity
GYO_3399	COG0628	permease
GYO_3400	COG0673	inositol 2-dehydrogenase activity
GYO_3401	COG4806	L-rhamnose isomerase
GYO_3402	COG3254	rhamnose metabolic process
GYO_3403	COG1070	Carbohydrate kinase
GYO_3404	COG1349	DNA-binding transcription factor activity
GYO_3405	COG3347	Dehydrogenase
GYO_3405	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3406	COG0840	transmembrane signaling receptor activity
GYO_3407	COG0840	transmembrane signaling receptor activity
GYO_3408	COG0840	transmembrane signaling receptor activity
GYO_3409	COG0840	transmembrane signaling receptor activity
GYO_3413	COG2070	2-Nitropropane dioxygenase
GYO_3414	COG0432	Pfam Uncharacterised protein family UPF0047
GYO_3415	COG0366	Alpha amylase catalytic
GYO_3416	COG1253	flavin adenine dinucleotide binding
GYO_3417	COG2738	Putative neutral zinc metallopeptidase
GYO_3420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GYO_3423	COG0166	Belongs to the GPI family
GYO_3424	COG1979	alcohol dehydrogenase
GYO_3425	COG1979	alcohol dehydrogenase
GYO_3426	COG2155	Conserved Protein
GYO_3427	COG1098	S1 RNA binding domain
GYO_3428	COG0436	Aminotransferase
GYO_3429	COG1522	sequence-specific DNA binding
GYO_3430	COG2267	carboxylic ester hydrolase activity
GYO_3432	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GYO_3433	COG2205	protein histidine kinase activity
GYO_3435	COG5018	Exonuclease
GYO_3437	COG2814	Major facilitator Superfamily
GYO_3438	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYO_3439	COG3011	Protein conserved in bacteria
GYO_3441	COG3290	protein histidine kinase activity
GYO_3442	COG4565	transcriptional regulatory protein
GYO_3447	COG3493	citrate carrier protein
GYO_3450	COG2111	Na H antiporter
GYO_3450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GYO_3451	COG2111	Na H antiporter
GYO_3452	COG1006	Multisubunit Na H antiporter MnhC subunit
GYO_3453	COG0651	ATP synthesis coupled electron transport
GYO_3454	COG1863	multisubunit Na H antiporter MnhE subunit
GYO_3455	COG2212	antiporter activity
GYO_3456	COG1320	monovalent cation:proton antiporter activity
GYO_3457	COG2050	protein possibly involved in aromatic compounds catabolism
GYO_3458	COG2197	response regulator
GYO_3459	COG4585	Histidine kinase
GYO_3461	COG0142	geranyltranstransferase activity
GYO_3465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GYO_3466	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GYO_3467	COG1335	isochorismatase
GYO_3468	COG5506	Protein of unknown function (DUF1694)
GYO_3471	COG0628	permease
GYO_3474	COG1418	mRNA catabolic process
GYO_3475	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3477	COG1511	domain protein
GYO_3478	COG1674	ftsk spoiiie
GYO_3478	COG0433	COG0433 Predicted ATPase
GYO_3479	COG4499	WXG100 protein secretion system (Wss), protein YukC
GYO_3480	COG5417	Belongs to the EsaB family
GYO_3481	COG4842	Belongs to the WXG100 family
GYO_3482	COG2508	Transcriptional regulator
GYO_3482	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GYO_3483	COG0686	Belongs to the AlaDH PNT family
GYO_3485	COG5634	Uncharacterized conserved protein (DUF2278)
GYO_3486	COG3251	PFAM MbtH domain protein
GYO_3487	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GYO_3488	COG3433	isochorismatase activity
GYO_3488	COG1535	isochorismatase
GYO_3489	COG1021	2,3-dihydroxybenzoate-AMP ligase
GYO_3490	COG1169	isochorismate synthase
GYO_3491	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3493	COG2819	hydrolase of the alpha beta superfamily
GYO_3494	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GYO_3495	COG1268	BioY protein
GYO_3496	COG2056	Na+-H+ antiporter family
GYO_3497	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GYO_3498	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GYO_3499	COG3584	3D domain protein
GYO_3502	COG1252	NADH dehydrogenase
GYO_3503	COG0492	ferredoxin-NADP+ reductase activity
GYO_3505	COG0516	GMP reductase activity
GYO_3506	COG2808	Putative FMN-binding domain
GYO_3507	COG0456	acetyltransferase
GYO_3509	COG0316	Belongs to the HesB IscA family
GYO_3510	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GYO_3511	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GYO_3512	COG4844	belongs to the
GYO_3513	COG1252	NADH dehydrogenase
GYO_3514	COG4837	Protein of unknown function (DUF1462)
GYO_3515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GYO_3516	COG4946	Tricorn protease homolog
GYO_3516	COG1506	peptidase
GYO_3516	COG0823	Involved in the tonB-independent uptake of proteins
GYO_3517	COG0083	homoserine kinase activity
GYO_3518	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GYO_3519	COG0460	homoserine dehydrogenase
GYO_3520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GYO_3521	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GYO_3522	COG0647	UMP catabolic process
GYO_3523	COG2445	Protein of unknown function DUF86
GYO_3524	COG4470	Protein conserved in bacteria
GYO_3526	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GYO_3527	COG0739	heme binding
GYO_3529	COG3377	Domain of unknown function (DUF1805)
GYO_3530	COG0737	Belongs to the 5'-nucleotidase family
GYO_3531	COG0730	response to heat
GYO_3532	COG1801	Protein of unknown function DUF72
GYO_3534	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GYO_3535	COG2508	Transcriptional regulator
GYO_3536	COG2233	PERMEase
GYO_3537	COG2233	PERMEase
GYO_3538	COG3648	Uricase
GYO_3538	COG3195	allantoin biosynthetic process
GYO_3539	COG2351	hydroxyisourate hydrolase activity
GYO_3540	COG0457	Tetratricopeptide repeat
GYO_3544	COG0785	Cytochrome C biogenesis protein
GYO_3545	COG2080	2 iron, 2 sulfur cluster binding
GYO_3546	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GYO_3547	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GYO_3548	COG2068	MobA-Related Protein
GYO_3549	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GYO_3550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GYO_3551	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GYO_3552	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYO_3554	COG2356	endonuclease I
GYO_3555	COG3842	ATPase activity
GYO_3556	COG2188	Transcriptional regulator
GYO_3557	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYO_3558	COG0395	ABC-type sugar transport system, permease component
GYO_3559	COG1175	transmembrane transport
GYO_3560	COG1653	transport
GYO_3561	COG2222	sugar isomerase
GYO_3562	COG0322	excinuclease ABC activity
GYO_3563	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYO_3566	COG0346	lactoylglutathione lyase activity
GYO_3567	COG0719	Fe-S assembly protein
GYO_3568	COG0822	iron-sulfur transferase activity
GYO_3569	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GYO_3570	COG0719	Fe-S assembly protein
GYO_3571	COG0396	ATPase activity
GYO_3573	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GYO_3574	COG1464	Belongs to the NlpA lipoprotein family
GYO_3575	COG2011	ABC-type metal ion transport system permease component
GYO_3576	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GYO_3579	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYO_3580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GYO_3582	COG0509	glycine decarboxylation via glycine cleavage system
GYO_3583	COG1393	Belongs to the ArsC family
GYO_3584	COG1960	acyl-CoA dehydrogenase activity
GYO_3585	COG0183	Belongs to the thiolase family
GYO_3586	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYO_3586	COG1024	Enoyl-CoA hydratase
GYO_3588	COG0506	proline dehydrogenase activity
GYO_3590	COG5577	PFAM Coat F domain
GYO_3591	COG1846	Transcriptional regulator
GYO_3592	COG0477	Major facilitator Superfamily
GYO_3593	COG1942	4-Oxalocrotonate Tautomerase
GYO_3594	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3595	COG0583	DNA-binding transcription factor activity
GYO_3597	COG1120	ATPase activity
GYO_3601	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3602	COG0783	Belongs to the Dps family
GYO_3603	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYO_3605	COG0745	RESPONSE REGULATOR receiver
GYO_3606	COG2205	protein histidine kinase activity
GYO_3606	COG2770	Histidine kinase
GYO_3608	COG1309	transcriptional regulator
GYO_3609	COG0114	fumarate hydratase activity
GYO_3611	COG0697	spore germination
GYO_3612	COG0814	amino acid
GYO_3614	COG2197	response regulator
GYO_3615	COG4585	Histidine kinase
GYO_3616	COG4758	membrane
GYO_3617	COG3595	metallopeptidase activity
GYO_3618	COG1842	Phage shock protein A
GYO_3619	COG4758	membrane
GYO_3621	COG2814	Major facilitator Superfamily
GYO_3622	COG2096	Adenosyltransferase
GYO_3623	COG1120	ATPase activity
GYO_3624	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_3625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYO_3626	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3627	COG3386	PFAM SMP-30 Gluconolaconase
GYO_3628	COG2205	protein histidine kinase activity
GYO_3629	COG0745	RESPONSE REGULATOR receiver
GYO_3631	COG1191	sigma factor activity
GYO_3633	COG2140	Oxalate decarboxylase
GYO_3635	COG0577	efflux transmembrane transporter activity
GYO_3636	COG1136	(ABC) transporter
GYO_3637	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GYO_3638	COG1120	ATPase activity
GYO_3639	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_3640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYO_3641	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYO_3644	COG0531	amino acid
GYO_3646	COG1988	membrane-bound metal-dependent
GYO_3647	COG1368	sulfuric ester hydrolase activity
GYO_3648	COG1910	domain protein
GYO_3649	COG0725	ABC transporter, periplasmic molybdate-binding protein
GYO_3650	COG4149	molybdate abc transporter
GYO_3651	COG0656	L-ascorbic acid biosynthetic process
GYO_3654	COG0025	NhaP-type Na H and K H
GYO_3655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GYO_3656	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GYO_3657	COG3973	AAA domain
GYO_3659	COG2860	membrane
GYO_3660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GYO_3661	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GYO_3662	COG2217	Heavy metal translocating P-type atpase
GYO_3663	COG2217	Heavy metal translocating P-type atpase
GYO_3664	COG2608	mercury ion transmembrane transporter activity
GYO_3665	COG1937	Protein conserved in bacteria
GYO_3666	COG0673	inositol 2-dehydrogenase activity
GYO_3667	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GYO_3668	COG1289	transmembrane transporter activity
GYO_3669	COG1802	Transcriptional regulator
GYO_3670	COG0697	spore germination
GYO_3673	COG2076	Multidrug Resistance protein
GYO_3674	COG1309	transcriptional regulator
GYO_3675	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_3677	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GYO_3678	COG0557	exoribonuclease II activity
GYO_3679	COG1647	Serine aminopeptidase, S33
GYO_3680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GYO_3681	COG0596	Alpha beta hydrolase
GYO_3682	COG1476	TRANSCRIPTIONal
GYO_3683	COG1396	sequence-specific DNA binding
GYO_3684	COG1396	sequence-specific DNA binding
GYO_3685	COG1733	regulation of RNA biosynthetic process
GYO_3686	COG0840	transmembrane signaling receptor activity
GYO_3697	COG1174	glycine betaine transport
GYO_3698	COG1732	Glycine betaine
GYO_3699	COG1174	glycine betaine transport
GYO_3700	COG1125	glycine betaine transport
GYO_3700	COG0517	IMP dehydrogenase activity
GYO_3702	COG1510	regulation of RNA biosynthetic process
GYO_3703	COG1174	glycine betaine transport
GYO_3704	COG1732	Glycine betaine
GYO_3705	COG1174	glycine betaine transport
GYO_3706	COG1125	glycine betaine transport
GYO_3706	COG0517	IMP dehydrogenase activity
GYO_3707	COG1510	regulation of RNA biosynthetic process
GYO_3709	COG3064	Membrane
GYO_3710	COG4640	response to antibiotic
GYO_3712	COG0456	acetyltransferase
GYO_3714	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GYO_3715	COG0149	triose-phosphate isomerase activity
GYO_3716	COG0126	phosphoglycerate kinase activity
GYO_3718	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GYO_3719	COG2390	Transcriptional regulator
GYO_3721	COG2814	Major facilitator Superfamily
GYO_3722	COG1609	Transcriptional regulator
GYO_3723	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GYO_3725	COG0583	DNA-binding transcription factor activity
GYO_3726	COG0697	spore germination
GYO_3727	COG1113	amino acid transport
GYO_3728	COG3858	chitin binding
GYO_3729	COG2801	Transposase and inactivated derivatives
GYO_3731	COG3858	chitin binding
GYO_3732	COG1556	Lactate utilization protein
GYO_3733	COG1139	Iron-sulfur cluster binding protein
GYO_3734	COG0247	lactate metabolic process
GYO_3738	COG2197	response regulator
GYO_3739	COG4585	Histidine kinase
GYO_3740	COG0842	Transport permease protein
GYO_3741	COG1131	(ABC) transporter
GYO_3742	COG0596	Alpha beta hydrolase
GYO_3743	COG2208	phosphoserine phosphatase activity
GYO_3744	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GYO_3745	COG1874	Beta-galactosidase
GYO_3746	COG3833	ABC-type maltose transport systems, permease component
GYO_3747	COG1175	transmembrane transport
GYO_3748	COG2182	Extracellular solute-binding protein
GYO_3749	COG1609	Transcriptional regulator
GYO_3753	COG1620	l-lactate permease
GYO_3754	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GYO_3757	COG5039	Polysaccharide pyruvyl transferase
GYO_3758	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYO_3759	COG0110	maltose O-acetyltransferase activity
GYO_3760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GYO_3761	COG2244	polysaccharide biosynthetic process
GYO_3762	COG1216	Glycosyl transferase, family 2
GYO_3763	COG5039	Polysaccharide pyruvyl transferase
GYO_3764	COG1216	Glycosyl transferase, family 2
GYO_3766	COG0438	transferase activity, transferring glycosyl groups
GYO_3767	COG1215	transferase activity, transferring glycosyl groups
GYO_3768	COG0438	transferase activity, transferring glycosyl groups
GYO_3769	COG1086	Polysaccharide biosynthesis protein
GYO_3770	COG0489	protein tyrosine kinase activity
GYO_3771	COG3944	biosynthesis protein
GYO_3772	COG1396	sequence-specific DNA binding
GYO_3773	COG2272	Belongs to the type-B carboxylesterase lipase family
GYO_3775	COG3479	Phenolic acid decarboxylase
GYO_3777	COG1794	racemase activity, acting on amino acids and derivatives
GYO_3778	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GYO_3780	COG1621	beta-fructofuranosidase activity
GYO_3781	COG1621	beta-fructofuranosidase activity
GYO_3782	COG0531	amino acid
GYO_3783	COG1309	transcriptional regulator
GYO_3784	COG2076	Multidrug Resistance protein
GYO_3785	COG2076	Multidrug Resistance protein
GYO_3789	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GYO_3790	COG0366	Alpha amylase catalytic
GYO_3791	COG1554	hydrolase, family 65, central catalytic
GYO_3792	COG5521	maltodextrose utilization protein MalA
GYO_3793	COG3833	ABC-type maltose transport systems, permease component
GYO_3794	COG1175	transmembrane transport
GYO_3795	COG2182	Extracellular solute-binding protein
GYO_3796	COG0366	Alpha amylase catalytic
GYO_3797	COG1609	Transcriptional regulator
GYO_3798	COG1611	Belongs to the LOG family
GYO_3799	COG1694	Mazg nucleotide pyrophosphohydrolase
GYO_3800	COG0659	secondary active sulfate transmembrane transporter activity
GYO_3801	COG0288	reversible hydration of carbon dioxide
GYO_3802	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GYO_3803	COG0577	efflux transmembrane transporter activity
GYO_3804	COG1136	(ABC) transporter
GYO_3805	COG5002	protein histidine kinase activity
GYO_3806	COG0745	RESPONSE REGULATOR receiver
GYO_3808	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GYO_3809	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_3810	COG1481	regulation of sporulation
GYO_3811	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GYO_3812	COG1660	Displays ATPase and GTPase activities
GYO_3813	COG1051	belongs to the nudix hydrolase family
GYO_3815	COG0492	ferredoxin-NADP+ reductase activity
GYO_3816	COG0791	NLP P60 protein
GYO_3816	COG3883	PFAM NLP P60 protein
GYO_3817	COG0457	Tetratricopeptide repeat
GYO_3818	COG1132	(ABC) transporter
GYO_3823	COG0140	phosphoribosyl-ATP diphosphatase activity
GYO_3823	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GYO_3824	COG0107	imidazoleglycerol-phosphate synthase activity
GYO_3825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GYO_3826	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GYO_3827	COG0131	Imidazoleglycerol-phosphate dehydratase
GYO_3828	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GYO_3829	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GYO_3830	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GYO_3831	COG4990	cell redox homeostasis
GYO_3832	COG5297	Belongs to the glycosyl hydrolase family 6
GYO_3833	COG0110	maltose O-acetyltransferase activity
GYO_3834	COG0546	phosphoglycolate phosphatase activity
GYO_3835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GYO_3836	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GYO_3837	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GYO_3838	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GYO_3839	COG0363	glucosamine-6-phosphate deaminase activity
GYO_3841	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GYO_3842	COG1846	Transcriptional regulator
GYO_3843	COG2124	cytochrome p450
GYO_3846	COG1846	Transcriptional regulator
GYO_3847	COG2814	Major facilitator Superfamily
GYO_3848	COG1950	PFAM Membrane protein of
GYO_3849	COG1983	PspC domain protein
GYO_3850	COG3595	metallopeptidase activity
GYO_3853	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GYO_3854	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GYO_3855	COG0556	nucleotide-excision repair
GYO_3856	COG4897	Protein conserved in bacteria
GYO_3859	COG0574	Belongs to the PEP-utilizing enzyme family
GYO_3859	COG3848	Pyruvate phosphate dikinase
GYO_3860	COG1309	transcriptional regulator
GYO_3861	COG2814	Major facilitator Superfamily
GYO_3862	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYO_3864	COG3409	Peptidoglycan-binding domain 1 protein
GYO_3864	COG0793	Belongs to the peptidase S41A family
GYO_3865	COG2177	Part of the ABC transporter FtsEX involved in
GYO_3866	COG2884	Cell division ATP-binding protein ftsE
GYO_3867	COG2010	Cytochrome c
GYO_3868	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYO_3869	COG2801	Transposase and inactivated derivatives
GYO_3871	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GYO_3872	COG0653	protein targeting
GYO_3873	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GYO_3877	COG1516	flagellar protein fliS
GYO_3878	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GYO_3879	COG1334	flagellar protein FlaG
GYO_3880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GYO_3881	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GYO_3882	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GYO_3884	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GYO_3885	COG1256	bacterial-type flagellum assembly
GYO_3885	COG4786	Flagellar basal body rod
GYO_3886	COG3418	PFAM FlgN family protein
GYO_3887	COG2747	anti-sigma28 factor FlgM
GYO_3889	COG1040	competence protein
GYO_3891	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GYO_3892	COG1307	EDD domain protein, DegV family
GYO_3893	COG2197	response regulator
GYO_3894	COG4585	Histidine kinase
GYO_3895	COG1739	Uncharacterized protein family UPF0029
GYO_3896	COG1316	TRANSCRIPTIONal
GYO_3903	COG1131	(ABC) transporter
GYO_3905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYO_3906	COG0438	transferase activity, transferring glycosyl groups
GYO_3907	COG1215	transferase activity, transferring glycosyl groups
GYO_3908	COG3206	protein involved in exopolysaccharide biosynthesis
GYO_3909	COG3307	-O-antigen
GYO_3910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GYO_3911	COG0297	glycogen (starch) synthase activity
GYO_3911	COG0438	transferase activity, transferring glycosyl groups
GYO_3912	COG2244	polysaccharide biosynthetic process
GYO_3915	COG2247	cell wall binding repeat
GYO_3915	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYO_3916	COG2385	sporulation resulting in formation of a cellular spore
GYO_3916	COG2247	cell wall binding repeat
GYO_3918	COG1316	TRANSCRIPTIONal
GYO_3919	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GYO_3923	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GYO_3924	COG1134	teichoic acid transport
GYO_3925	COG1682	transport, permease protein
GYO_3927	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GYO_3929	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GYO_3937	COG4193	domain, Protein
GYO_3938	COG1482	cell wall glycoprotein biosynthetic process
GYO_3940	COG0814	amino acid
GYO_3942	COG2814	Major facilitator Superfamily
GYO_3943	COG1316	TRANSCRIPTIONal
GYO_3944	COG0561	phosphatase activity
GYO_3945	COG0791	NLP P60 protein
GYO_3947	COG2843	Capsule synthesis protein
GYO_3949	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GYO_3950	COG1609	Transcriptional regulator
GYO_3951	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYO_3952	COG1869	D-ribose catabolic process
GYO_3953	COG1129	ABC transporter
GYO_3954	COG1172	Belongs to the binding-protein-dependent transport system permease family
GYO_3955	COG1879	ABC-type sugar transport system periplasmic component
GYO_3956	COG3103	Sh3 type 3 domain protein
GYO_3958	COG2249	NAD(P)H dehydrogenase (quinone) activity
GYO_3959	COG3527	Alpha-acetolactate decarboxylase
GYO_3960	COG0028	Belongs to the TPP enzyme family
GYO_3961	COG0583	DNA-binding transcription factor activity
GYO_3962	COG5337	Spore coat protein CotH
GYO_3964	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GYO_3966	COG0405	Gamma-glutamyltransferase
GYO_3967	COG1522	sequence-specific DNA binding
GYO_3968	COG2059	Chromate
GYO_3969	COG2059	Chromate
GYO_3971	COG0655	NAD(P)H dehydrogenase (quinone) activity
GYO_3972	COG0583	DNA-binding transcription factor activity
GYO_3974	COG2207	Transcriptional regulator
GYO_3974	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYO_3980	COG5444	nuclease activity
GYO_3984	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GYO_3985	COG4464	protein tyrosine phosphatase activity
GYO_3986	COG0489	protein tyrosine kinase activity
GYO_3987	COG3944	biosynthesis protein
GYO_3989	COG4715	Zinc finger, swim domain protein
GYO_3990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GYO_3992	COG0561	phosphatase activity
GYO_3993	COG1349	DNA-binding transcription factor activity
GYO_3994	COG0629	single-stranded DNA binding
GYO_3997	COG3764	Sortase (surface protein transpeptidase)
GYO_3999	COG3279	Response regulator of the LytR AlgR family
GYO_4000	COG2972	Histidine kinase
GYO_4000	COG0745	RESPONSE REGULATOR receiver
GYO_4001	COG1970	mechanosensitive ion channel activity
GYO_4002	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GYO_4003	COG0457	Tetratricopeptide repeat
GYO_4004	COG4786	Flagellar basal body rod
GYO_4005	COG4786	Flagellar basal body rod
GYO_4006	COG1077	Cell shape determining protein MreB Mrl
GYO_4007	COG1609	Transcriptional regulator
GYO_4008	COG1846	Transcriptional regulator
GYO_4009	COG2814	Major facilitator Superfamily
GYO_4010	COG3420	alginic acid biosynthetic process
GYO_4011	COG1953	Uracil, thiamine, allantoin
GYO_4012	COG0477	Major facilitator Superfamily
GYO_4013	COG1335	isochorismatase
GYO_4015	COG0004	ammonium transporteR
GYO_4016	COG0347	Belongs to the P(II) protein family
GYO_4017	COG0671	phosphoesterase, PA-phosphatase related
GYO_4019	COG0739	heme binding
GYO_4020	COG1247	-acetyltransferase
GYO_4022	COG2089	acid synthase
GYO_4024	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYO_4025	COG0789	Transcriptional regulator
GYO_4027	COG2910	NAD(P)H-binding
GYO_4028	COG1959	2 iron, 2 sulfur cluster binding
GYO_4029	COG0804	urea catabolic process
GYO_4030	COG0832	Belongs to the urease beta subunit family
GYO_4031	COG0831	urea catabolic process
GYO_4033	COG0411	ABC transporter
GYO_4035	COG0559	Belongs to the binding-protein-dependent transport system permease family
GYO_4037	COG3237	CsbD-like
GYO_4038	COG1994	Peptidase M50
GYO_4039	COG0457	Tetratricopeptide repeat
GYO_4041	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GYO_4042	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GYO_4044	COG2304	oxidoreductase activity
GYO_4046	COG2304	oxidoreductase activity
GYO_4047	COG2385	sporulation resulting in formation of a cellular spore
GYO_4049	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GYO_4051	COG4836	Membrane
GYO_4055	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GYO_4056	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GYO_4057	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GYO_4058	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GYO_4059	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GYO_4061	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GYO_4062	COG0356	it plays a direct role in the translocation of protons across the membrane
GYO_4064	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GYO_4065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GYO_4066	COG4475	Protein of unknown function (DUF436)
GYO_4067	COG0698	ribose 5-phosphate isomerase
GYO_4069	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GYO_4070	COG1971	Probably functions as a manganese efflux pump
GYO_4071	COG0009	L-threonylcarbamoyladenylate synthase
GYO_4072	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GYO_4076	COG2890	protein-(glutamine-N5) methyltransferase activity
GYO_4077	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GYO_4078	COG0346	lactoylglutathione lyase activity
GYO_4079	COG0789	Transcriptional regulator
GYO_4080	COG0679	Auxin Efflux Carrier
GYO_4081	COG0281	malic enzyme
GYO_4082	COG1435	thymidine kinase activity
GYO_4083	COG0254	rRNA binding
GYO_4084	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GYO_4086	COG1494	fructose-1,6-bisphosphatase
GYO_4087	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GYO_4089	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GYO_4090	COG0191	fructose-bisphosphate aldolase activity
GYO_4091	COG2204	response regulator
GYO_4092	COG4821	SIS domain
GYO_4093	COG0504	CTP synthase activity
GYO_4095	COG3343	RNA polymerase activity
GYO_4096	COG1960	acyl-CoA dehydrogenase activity
GYO_4097	COG2181	nitrate reductase activity
GYO_4097	COG0247	lactate metabolic process
GYO_4098	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYO_4099	COG4294	response to UV
GYO_4101	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GYO_4102	COG1132	(ABC) transporter
GYO_4103	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYO_4105	COG2181	nitrate reductase activity
GYO_4106	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GYO_4107	COG1140	nitrate reductase beta subunit
GYO_4108	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GYO_4110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYO_4112	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYO_4113	COG2223	nitrite transmembrane transporter activity
GYO_4114	COG0018	arginyl-trna synthetase
GYO_4115	COG4506	Protein conserved in bacteria
GYO_4117	COG0535	radical SAM domain protein
GYO_4119	COG1131	(ABC) transporter
GYO_4124	COG3391	amine dehydrogenase activity
GYO_4126	COG0457	Tetratricopeptide repeat
GYO_4131	COG1131	(ABC) transporter
GYO_4133	COG0010	Belongs to the arginase family
GYO_4134	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GYO_4135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYO_4138	COG1994	Peptidase M50
GYO_4139	COG1942	4-Oxalocrotonate Tautomerase
GYO_4140	COG1846	Transcriptional regulator
GYO_4141	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GYO_4145	COG3465	dGTPase activity
GYO_4146	COG1078	dGTPase activity
GYO_4147	COG4844	belongs to the
GYO_4149	COG0697	spore germination
GYO_4150	COG0095	Lipoate-protein ligase
GYO_4151	COG0583	DNA-binding transcription factor activity
GYO_4152	COG0280	phosphate acetyltransferase
GYO_4154	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_4155	COG0436	Aminotransferase
GYO_4156	COG2814	Major facilitator Superfamily
GYO_4157	COG0151	Belongs to the GarS family
GYO_4158	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_4159	COG1917	Cupin 2, conserved barrel domain protein
GYO_4160	COG0077	Prephenate dehydratase
GYO_4161	COG2814	Major facilitator Superfamily
GYO_4162	COG0833	amino acid
GYO_4163	COG4187	Peptidase family M20/M25/M40
GYO_4164	COG1012	belongs to the aldehyde dehydrogenase family
GYO_4166	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYO_4170	COG1088	dTDP-glucose 4,6-dehydratase activity
GYO_4171	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GYO_4173	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GYO_4174	COG2089	acid synthase
GYO_4175	COG0456	acetyltransferase
GYO_4176	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYO_4177	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GYO_4178	COG0463	Glycosyl transferase, family 2
GYO_4181	COG2363	Small membrane protein
GYO_4182	COG2233	PERMEase
GYO_4185	COG1012	belongs to the aldehyde dehydrogenase family
GYO_4186	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GYO_4187	COG1216	Glycosyl transferase, family 2
GYO_4190	COG1695	Transcriptional regulator
GYO_4192	COG0351	phosphomethylpyrimidine kinase
GYO_4194	COG1621	beta-fructofuranosidase activity
GYO_4195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_4195	COG1263	PTS System
GYO_4196	COG2116	formate transmembrane transporter activity
GYO_4197	COG3711	transcriptional antiterminator
GYO_4199	COG1404	Belongs to the peptidase S8 family
GYO_4200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GYO_4201	COG0778	Nitroreductase
GYO_4203	COG0772	Belongs to the SEDS family
GYO_4211	COG2261	transglycosylase associated protein
GYO_4212	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GYO_4213	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GYO_4214	COG2246	polysaccharide biosynthetic process
GYO_4215	COG1309	transcriptional regulator
GYO_4217	COG3162	membrane
GYO_4218	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYO_4219	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GYO_4220	COG2837	iron assimilation
GYO_4221	COG2822	iron ion transport
GYO_4222	COG0672	)-iron permease
GYO_4224	COG0352	thiamine-phosphate diphosphorylase activity
GYO_4225	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GYO_4226	COG0583	DNA-binding transcription factor activity
GYO_4227	COG1380	Effector of murein hydrolase LrgA
GYO_4228	COG1346	cytolysis
GYO_4231	COG4895	conserved protein (DUF2196)
GYO_4232	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GYO_4233	COG0346	lactoylglutathione lyase activity
GYO_4235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GYO_4237	COG1404	Belongs to the peptidase S8 family
GYO_4238	COG1263	PTS System
GYO_4238	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_4239	COG3711	transcriptional antiterminator
GYO_4240	COG1442	glycosyl transferase family 8
GYO_4241	COG5522	Integral membrane protein (intg_mem_TP0381)
GYO_4242	COG1846	Transcriptional regulator
GYO_4243	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GYO_4245	COG2234	aminopeptidase activity
GYO_4246	COG2357	RelA SpoT domain protein
GYO_4247	COG1575	Belongs to the MenA family. Type 1 subfamily
GYO_4251	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GYO_4252	COG1696	Membrane protein involved in D-alanine export
GYO_4253	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYO_4254	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GYO_4255	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GYO_4256	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYO_4257	COG1486	melibiose metabolic process
GYO_4258	COG1447	Phosphotransferase system cellobiose-specific component IIA
GYO_4259	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GYO_4260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GYO_4261	COG3711	transcriptional antiterminator
GYO_4261	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYO_4263	COG2094	Belongs to the DNA glycosylase MPG family
GYO_4264	COG0753	catalase activity
GYO_4265	COG2814	Major facilitator Superfamily
GYO_4266	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GYO_4267	COG1131	(ABC) transporter
GYO_4271	COG1595	DNA-templated transcription, initiation
GYO_4272	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GYO_4273	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GYO_4274	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GYO_4275	COG4988	ABC transporter
GYO_4276	COG1294	oxidase, subunit
GYO_4277	COG1271	oxidase subunit
GYO_4278	COG3493	citrate carrier protein
GYO_4279	COG0501	Belongs to the peptidase M48B family
GYO_4281	COG0726	polysaccharide deacetylase
GYO_4285	COG3842	ATPase activity
GYO_4286	COG2508	Transcriptional regulator
GYO_4287	COG1012	belongs to the aldehyde dehydrogenase family
GYO_4288	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYO_4290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GYO_4293	COG4585	Histidine kinase
GYO_4294	COG2197	response regulator
GYO_4295	COG2195	Cleaves the N-terminal amino acid of tripeptides
GYO_4298	COG4894	glucomannan catabolic process
GYO_4300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GYO_4301	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GYO_4302	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_4303	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GYO_4304	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GYO_4305	COG2610	gluconate transmembrane transporter activity
GYO_4306	COG0500	methyltransferase
GYO_4307	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GYO_4310	COG0753	catalase activity
GYO_4310	COG0693	protein deglycase activity
GYO_4311	COG2851	Citrate transporter
GYO_4312	COG2323	membrane
GYO_4314	COG2723	6-phospho-beta-galactosidase activity
GYO_4315	COG2190	(PTS) system
GYO_4315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_4315	COG1263	PTS System
GYO_4317	COG3711	transcriptional antiterminator
GYO_4320	COG2270	Major facilitator Superfamily
GYO_4321	COG0513	Belongs to the DEAD box helicase family
GYO_4322	COG3401	FG-GAP repeat protein
GYO_4322	COG2755	lipolytic protein G-D-S-L family
GYO_4327	COG0697	spore germination
GYO_4331	COG0697	spore germination
GYO_4332	COG0589	response to stress
GYO_4333	COG2723	6-phospho-beta-galactosidase activity
GYO_4334	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYO_4334	COG2190	(PTS) system
GYO_4334	COG1263	PTS System
GYO_4336	COG5444	nuclease activity
GYO_4339	COG3507	Belongs to the glycosyl hydrolase 43 family
GYO_4342	COG2986	histidine ammonia-lyase
GYO_4343	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GYO_4344	COG1228	amidohydrolase
GYO_4345	COG0010	Belongs to the arginase family
GYO_4346	COG0833	amino acid
GYO_4347	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GYO_4348	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GYO_4349	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GYO_4351	COG2390	Transcriptional regulator
GYO_4353	COG3192	ethanolamine utilization protein
GYO_4354	COG2079	MmgE PrpD family protein
GYO_4356	COG1126	abc transporter atp-binding protein
GYO_4357	COG0765	amino acid transport
GYO_4358	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GYO_4361	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GYO_4362	COG0561	phosphatase activity
GYO_4368	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYO_4369	COG5294	Protein conserved in bacteria
GYO_4370	COG0577	efflux transmembrane transporter activity
GYO_4371	COG1136	(ABC) transporter
GYO_4372	COG2205	protein histidine kinase activity
GYO_4373	COG0745	RESPONSE REGULATOR receiver
GYO_4374	COG0191	fructose-bisphosphate aldolase activity
GYO_4376	COG1082	Xylose isomerase domain protein TIM barrel
GYO_4377	COG0673	inositol 2-dehydrogenase activity
GYO_4378	COG2814	Major facilitator Superfamily
GYO_4379	COG1082	Xylose isomerase domain protein TIM barrel
GYO_4380	COG3962	Belongs to the TPP enzyme family
GYO_4381	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYO_4383	COG1012	belongs to the aldehyde dehydrogenase family
GYO_4384	COG1349	DNA-binding transcription factor activity
GYO_4385	COG0667	Aldo Keto reductase
GYO_4388	COG2814	Major facilitator Superfamily
GYO_4389	COG0326	Molecular chaperone. Has ATPase activity
GYO_4391	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_4392	COG1309	transcriptional regulator
GYO_4393	COG1012	belongs to the aldehyde dehydrogenase family
GYO_4394	COG1714	RDD family
GYO_4396	COG1714	RDD family
GYO_4397	COG2311	Membrane
GYO_4398	COG1917	Cupin 2, conserved barrel domain protein
GYO_4399	COG1309	transcriptional regulator
GYO_4400	COG1028	Short-chain dehydrogenase reductase Sdr
GYO_4401	COG1846	Transcriptional regulator
GYO_4402	COG1380	Effector of murein hydrolase LrgA
GYO_4403	COG1346	cytolysis
GYO_4406	COG5039	Polysaccharide pyruvyl transferase
GYO_4407	COG1929	Belongs to the glycerate kinase type-1 family
GYO_4408	COG1802	Transcriptional regulator
GYO_4409	COG1070	Carbohydrate kinase
GYO_4410	COG2610	gluconate transmembrane transporter activity
GYO_4411	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GYO_4413	COG0450	alkyl hydroperoxide reductase
GYO_4414	COG3634	alkyl hydroperoxide reductase activity
GYO_4415	COG3177	Filamentation induced by cAMP protein fic
GYO_4418	COG2723	6-phospho-beta-galactosidase activity
GYO_4420	COG2188	Transcriptional regulator
GYO_4423	COG1131	(ABC) transporter
GYO_4424	COG1994	Peptidase M50
GYO_4425	COG0535	radical SAM domain protein
GYO_4427	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GYO_4431	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GYO_4433	COG1063	alcohol dehydrogenase
GYO_4437	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GYO_4438	COG0456	acetyltransferase
GYO_4439	COG0457	Tetratricopeptide repeat
GYO_4441	COG0010	Belongs to the arginase family
GYO_4442	COG0833	amino acid
GYO_4443	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GYO_4444	COG3829	transcription factor binding
GYO_4445	COG5002	protein histidine kinase activity
GYO_4445	COG3850	Histidine kinase
GYO_4449	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYO_4450	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GYO_4451	COG4853	Protein conserved in bacteria
GYO_4452	COG4863	YycH protein
GYO_4453	COG5002	protein histidine kinase activity
GYO_4454	COG0745	RESPONSE REGULATOR receiver
GYO_4460	COG0346	lactoylglutathione lyase activity
GYO_4462	COG0305	Participates in initiation and elongation during chromosome replication
GYO_4465	COG3093	addiction module antidote protein HigA
GYO_4466	COG2807	transmembrane transport
GYO_4467	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GYO_4468	COG0359	binds to the 23S rRNA
GYO_4469	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GYO_4470	COG4241	membrane
GYO_4472	COG5577	PFAM Coat F domain
GYO_4473	COG1733	regulation of RNA biosynthetic process
GYO_4474	COG1227	inorganic diphosphatase activity
GYO_4476	COG2271	Major facilitator Superfamily
GYO_4478	COG4978	Transcriptional regulator
GYO_4478	COG0789	Transcriptional regulator
GYO_4480	COG4319	ketosteroid isomerase
GYO_4481	COG1357	PFAM Pentapeptide repeats (8 copies)
GYO_4482	COG2814	Major facilitator Superfamily
GYO_4483	COG0583	DNA-binding transcription factor activity
GYO_4484	COG2153	protein acetylation
GYO_4487	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYO_4488	COG1733	regulation of RNA biosynthetic process
GYO_4490	COG1846	Transcriptional regulator
GYO_4491	COG2153	protein acetylation
GYO_4492	COG2364	Membrane
GYO_4495	COG0640	Transcriptional regulator
GYO_4496	COG1331	Highly conserved protein containing a thioredoxin domain
GYO_4497	COG1266	CAAX protease self-immunity
GYO_4498	COG0477	Major facilitator Superfamily
GYO_4498	COG2814	Major facilitator Superfamily
GYO_4499	COG0110	maltose O-acetyltransferase activity
GYO_4500	COG0346	lactoylglutathione lyase activity
GYO_4501	COG1609	Transcriptional regulator
GYO_4502	COG0708	Exodeoxyribonuclease III
GYO_4503	COG0629	single-stranded DNA binding
GYO_4504	COG0360	Binds together with S18 to 16S ribosomal RNA
GYO_4505	COG0012	GTP binding
GYO_4506	COG0012	GTP binding
GYO_4507	COG0243	molybdopterin cofactor binding
GYO_4508	COG4481	Protein conserved in bacteria
GYO_4509	COG3949	Membrane
GYO_4511	COG1475	DNA binding
GYO_4512	COG1192	Involved in chromosome partitioning
GYO_4514	COG1475	DNA binding
GYO_4515	COG0357	Ribosomal RNA small subunit methyltransferase G
GYO_4516	COG0445	tRNA wobble uridine modification
GYO_4517	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GYO_4518	COG1847	R3H domain protein
GYO_4519	COG0706	membrane insertase activity
GYO_4520	COG0594	ribonuclease P activity
GYO_4551	COG0039	L-malate dehydrogenase activity
GYO_4553	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYO_4554	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GYO_4555	COG0840	transmembrane signaling receptor activity
GYO_4556	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GYO_4558	COG2252	PERMEase