locus-tag	class	description
D9C08_00010	COG1132	(ABC) transporter
D9C08_00030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9C08_00030	COG0140	phosphoribosyl-ATP diphosphatase activity
D9C08_00035	COG0107	imidazoleglycerol-phosphate synthase activity
D9C08_00040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9C08_00045	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9C08_00050	COG0131	Imidazoleglycerol-phosphate dehydratase
D9C08_00055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9C08_00060	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9C08_00065	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9C08_00070	COG4990	cell redox homeostasis
D9C08_00075	COG5297	Belongs to the glycosyl hydrolase family 6
D9C08_00085	COG0110	maltose O-acetyltransferase activity
D9C08_00090	COG0546	phosphoglycolate phosphatase activity
D9C08_00095	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9C08_00100	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9C08_00105	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9C08_00110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9C08_00115	COG0363	glucosamine-6-phosphate deaminase activity
D9C08_00125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9C08_00140	COG1950	PFAM Membrane protein of
D9C08_00145	COG1983	PspC domain protein
D9C08_00150	COG3595	metallopeptidase activity
D9C08_00165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C08_00170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9C08_00175	COG0556	nucleotide-excision repair
D9C08_00180	COG4897	Protein conserved in bacteria
D9C08_00185	COG3848	Pyruvate phosphate dikinase
D9C08_00185	COG0574	Belongs to the PEP-utilizing enzyme family
D9C08_00190	COG1309	transcriptional regulator
D9C08_00195	COG2814	Major facilitator Superfamily
D9C08_00200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C08_00210	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_00210	COG0793	Belongs to the peptidase S41A family
D9C08_00215	COG2177	Part of the ABC transporter FtsEX involved in
D9C08_00220	COG2884	Cell division ATP-binding protein ftsE
D9C08_00225	COG2010	Cytochrome c
D9C08_00230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C08_00240	COG0653	protein targeting
D9C08_00250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9C08_00265	COG1516	flagellar protein fliS
D9C08_00270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9C08_00275	COG1334	flagellar protein FlaG
D9C08_00280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C08_00285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9C08_00290	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9C08_00300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C08_00305	COG4786	Flagellar basal body rod
D9C08_00305	COG1256	bacterial-type flagellum assembly
D9C08_00310	COG3418	PFAM FlgN family protein
D9C08_00315	COG2747	anti-sigma28 factor FlgM
D9C08_00325	COG1040	competence protein
D9C08_00335	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9C08_00340	COG1307	EDD domain protein, DegV family
D9C08_00345	COG2197	response regulator
D9C08_00350	COG4585	Histidine kinase
D9C08_00355	COG1739	Uncharacterized protein family UPF0029
D9C08_00360	COG1316	TRANSCRIPTIONal
D9C08_00395	COG1131	(ABC) transporter
D9C08_00405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C08_00410	COG0438	transferase activity, transferring glycosyl groups
D9C08_00415	COG1215	transferase activity, transferring glycosyl groups
D9C08_00420	COG3206	protein involved in exopolysaccharide biosynthesis
D9C08_00425	COG3307	-O-antigen
D9C08_00435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C08_00440	COG0438	transferase activity, transferring glycosyl groups
D9C08_00440	COG0297	glycogen (starch) synthase activity
D9C08_00445	COG2244	polysaccharide biosynthetic process
D9C08_00460	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9C08_00465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C08_00475	COG1134	teichoic acid transport
D9C08_00480	COG1682	transport, permease protein
D9C08_00495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C08_00495	COG0463	Glycosyl transferase, family 2
D9C08_00500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C08_00505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9C08_00510	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D9C08_00515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C08_00520	COG4193	domain, Protein
D9C08_00525	COG1482	cell wall glycoprotein biosynthetic process
D9C08_00550	COG1316	TRANSCRIPTIONal
D9C08_00555	COG0561	phosphatase activity
D9C08_00560	COG0791	NLP P60 protein
D9C08_00575	COG2843	Capsule synthesis protein
D9C08_00585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C08_00600	COG1609	Transcriptional regulator
D9C08_00605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C08_00610	COG1869	D-ribose catabolic process
D9C08_00615	COG1129	ABC transporter
D9C08_00620	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9C08_00625	COG1879	ABC-type sugar transport system periplasmic component
D9C08_00630	COG3103	Sh3 type 3 domain protein
D9C08_00640	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C08_00645	COG3527	Alpha-acetolactate decarboxylase
D9C08_00650	COG0028	Belongs to the TPP enzyme family
D9C08_00655	COG0583	DNA-binding transcription factor activity
D9C08_00675	COG5337	Spore coat protein CotH
D9C08_00685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C08_00695	COG0405	Gamma-glutamyltransferase
D9C08_00700	COG1522	sequence-specific DNA binding
D9C08_00705	COG2059	Chromate
D9C08_00710	COG2059	Chromate
D9C08_00720	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C08_00725	COG0583	DNA-binding transcription factor activity
D9C08_00755	COG5444	nuclease activity
D9C08_00775	COG3878	Protein conserved in bacteria
D9C08_00780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C08_00785	COG4464	protein tyrosine phosphatase activity
D9C08_00790	COG0489	protein tyrosine kinase activity
D9C08_00795	COG3944	biosynthesis protein
D9C08_00805	COG4715	Zinc finger, swim domain protein
D9C08_00810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C08_00820	COG0561	phosphatase activity
D9C08_00825	COG1349	DNA-binding transcription factor activity
D9C08_00830	COG0629	single-stranded DNA binding
D9C08_00845	COG3764	Sortase (surface protein transpeptidase)
D9C08_00850	COG0745	RESPONSE REGULATOR receiver
D9C08_00850	COG2972	Histidine kinase
D9C08_00855	COG1970	mechanosensitive ion channel activity
D9C08_00860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C08_00865	COG0457	Tetratricopeptide repeat
D9C08_00870	COG4786	Flagellar basal body rod
D9C08_00875	COG4786	Flagellar basal body rod
D9C08_00880	COG1077	Cell shape determining protein MreB Mrl
D9C08_00885	COG1609	Transcriptional regulator
D9C08_00895	COG1846	Transcriptional regulator
D9C08_00900	COG2814	Major facilitator Superfamily
D9C08_00905	COG3420	alginic acid biosynthetic process
D9C08_00910	COG1953	Uracil, thiamine, allantoin
D9C08_00915	COG0477	Major facilitator Superfamily
D9C08_00920	COG1335	isochorismatase
D9C08_00930	COG0004	ammonium transporteR
D9C08_00935	COG0347	Belongs to the P(II) protein family
D9C08_00940	COG0671	phosphoesterase, PA-phosphatase related
D9C08_00950	COG0739	heme binding
D9C08_00955	COG1247	-acetyltransferase
D9C08_00965	COG2089	acid synthase
D9C08_00975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C08_00980	COG0789	Transcriptional regulator
D9C08_00995	COG1959	2 iron, 2 sulfur cluster binding
D9C08_01000	COG0804	urea catabolic process
D9C08_01005	COG0832	Belongs to the urease beta subunit family
D9C08_01010	COG0831	urea catabolic process
D9C08_01025	COG3237	CsbD-like
D9C08_01030	COG1994	Peptidase M50
D9C08_01035	COG0457	Tetratricopeptide repeat
D9C08_01045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9C08_01050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9C08_01060	COG2304	oxidoreductase activity
D9C08_01070	COG2304	oxidoreductase activity
D9C08_01075	COG2385	sporulation resulting in formation of a cellular spore
D9C08_01080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C08_01090	COG4836	Membrane
D9C08_01100	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9C08_01105	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9C08_01110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9C08_01115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9C08_01120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C08_01125	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9C08_01130	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C08_01135	COG0356	it plays a direct role in the translocation of protons across the membrane
D9C08_01145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9C08_01150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9C08_01155	COG4475	Protein of unknown function (DUF436)
D9C08_01160	COG0698	ribose 5-phosphate isomerase
D9C08_01165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C08_01170	COG1971	Probably functions as a manganese efflux pump
D9C08_01175	COG0009	L-threonylcarbamoyladenylate synthase
D9C08_01180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9C08_01200	COG2890	protein-(glutamine-N5) methyltransferase activity
D9C08_01205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9C08_01210	COG0346	lactoylglutathione lyase activity
D9C08_01215	COG0789	Transcriptional regulator
D9C08_01220	COG0679	Auxin Efflux Carrier
D9C08_01225	COG0281	malic enzyme
D9C08_01230	COG1435	thymidine kinase activity
D9C08_01235	COG0254	rRNA binding
D9C08_01240	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9C08_01250	COG1494	fructose-1,6-bisphosphatase
D9C08_01255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C08_01260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9C08_01265	COG0191	fructose-bisphosphate aldolase activity
D9C08_01270	COG2204	response regulator
D9C08_01275	COG4821	SIS domain
D9C08_01285	COG0504	CTP synthase activity
D9C08_01290	COG3343	RNA polymerase activity
D9C08_01295	COG1960	acyl-CoA dehydrogenase activity
D9C08_01300	COG2181	nitrate reductase activity
D9C08_01300	COG0247	lactate metabolic process
D9C08_01305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C08_01310	COG4294	response to UV
D9C08_01325	COG0018	arginyl-trna synthetase
D9C08_01330	COG4506	Protein conserved in bacteria
D9C08_01345	COG0535	radical SAM domain protein
D9C08_01355	COG1131	(ABC) transporter
D9C08_01360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C08_01365	COG0612	Peptidase, M16
D9C08_01370	COG0612	Peptidase, M16
D9C08_01380	COG3391	amine dehydrogenase activity
D9C08_01395	COG0457	Tetratricopeptide repeat
D9C08_01410	COG0010	Belongs to the arginase family
D9C08_01415	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9C08_01420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C08_01435	COG1994	Peptidase M50
D9C08_01440	COG1942	4-Oxalocrotonate Tautomerase
D9C08_01445	COG1846	Transcriptional regulator
D9C08_01450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C08_01460	COG0477	Major facilitator Superfamily
D9C08_01465	COG1959	2 iron, 2 sulfur cluster binding
D9C08_01470	COG3465	dGTPase activity
D9C08_01475	COG1078	dGTPase activity
D9C08_01480	COG4844	belongs to the
D9C08_01490	COG0697	spore germination
D9C08_01495	COG0095	Lipoate-protein ligase
D9C08_01500	COG0583	DNA-binding transcription factor activity
D9C08_01505	COG0280	phosphate acetyltransferase
D9C08_01515	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_01520	COG0436	Aminotransferase
D9C08_01525	COG2814	Major facilitator Superfamily
D9C08_01530	COG0151	Belongs to the GarS family
D9C08_01535	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_01540	COG1917	Cupin 2, conserved barrel domain protein
D9C08_01545	COG0077	Prephenate dehydratase
D9C08_01555	COG2814	Major facilitator Superfamily
D9C08_01560	COG0833	amino acid
D9C08_01565	COG4187	Peptidase family M20/M25/M40
D9C08_01570	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_01575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C08_01585	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D9C08_01590	COG1091	dTDP-4-dehydrorhamnose reductase activity
D9C08_01595	COG1088	dTDP-glucose 4,6-dehydratase activity
D9C08_01600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9C08_01605	COG3980	spore coat polysaccharide biosynthesis protein
D9C08_01610	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D9C08_01615	COG2089	acid synthase
D9C08_01620	COG0456	acetyltransferase
D9C08_01625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C08_01630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C08_01635	COG0463	Glycosyl transferase, family 2
D9C08_01650	COG2363	Small membrane protein
D9C08_01655	COG2233	PERMEase
D9C08_01665	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_01670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9C08_01675	COG1216	Glycosyl transferase, family 2
D9C08_01680	COG0351	phosphomethylpyrimidine kinase
D9C08_01700	COG1621	beta-fructofuranosidase activity
D9C08_01705	COG1263	PTS System
D9C08_01705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_01710	COG2116	formate transmembrane transporter activity
D9C08_01715	COG3711	transcriptional antiterminator
D9C08_01725	COG1404	Belongs to the peptidase S8 family
D9C08_01730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C08_01735	COG0778	Nitroreductase
D9C08_01740	COG0772	Belongs to the SEDS family
D9C08_01755	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C08_01760	COG1845	cytochrome c oxidase, subunit III
D9C08_01765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C08_01770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C08_01775	COG2261	transglycosylase associated protein
D9C08_01780	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9C08_01785	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9C08_01790	COG2246	polysaccharide biosynthetic process
D9C08_01795	COG1309	transcriptional regulator
D9C08_01805	COG3162	membrane
D9C08_01810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C08_01815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9C08_01820	COG2837	iron assimilation
D9C08_01825	COG2822	iron ion transport
D9C08_01830	COG0672	)-iron permease
D9C08_01835	COG0352	thiamine-phosphate diphosphorylase activity
D9C08_01840	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9C08_01845	COG0583	DNA-binding transcription factor activity
D9C08_01850	COG1380	Effector of murein hydrolase LrgA
D9C08_01855	COG1346	cytolysis
D9C08_01860	COG2814	Major facilitator Superfamily
D9C08_01865	COG4895	conserved protein (DUF2196)
D9C08_01870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9C08_01875	COG0346	lactoylglutathione lyase activity
D9C08_01885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C08_01895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_01895	COG1263	PTS System
D9C08_01900	COG3711	transcriptional antiterminator
D9C08_01905	COG1442	glycosyl transferase family 8
D9C08_01910	COG5522	Integral membrane protein (intg_mem_TP0381)
D9C08_01915	COG1846	Transcriptional regulator
D9C08_01920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C08_01925	COG2234	aminopeptidase activity
D9C08_01935	COG2357	RelA SpoT domain protein
D9C08_01945	COG1575	Belongs to the MenA family. Type 1 subfamily
D9C08_01965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C08_01970	COG1696	Membrane protein involved in D-alanine export
D9C08_01975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C08_01980	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9C08_01990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C08_01995	COG1486	melibiose metabolic process
D9C08_02000	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C08_02005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C08_02010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C08_02015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_02015	COG3711	transcriptional antiterminator
D9C08_02025	COG2094	Belongs to the DNA glycosylase MPG family
D9C08_02030	COG0753	catalase activity
D9C08_02035	COG2814	Major facilitator Superfamily
D9C08_02040	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C08_02045	COG1131	(ABC) transporter
D9C08_02065	COG1595	DNA-templated transcription, initiation
D9C08_02070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C08_02075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9C08_02080	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9C08_02085	COG4988	ABC transporter
D9C08_02090	COG1294	oxidase, subunit
D9C08_02095	COG1271	oxidase subunit
D9C08_02100	COG3493	citrate carrier protein
D9C08_02105	COG0501	Belongs to the peptidase M48B family
D9C08_02115	COG0726	polysaccharide deacetylase
D9C08_02120	COG3842	ATPase activity
D9C08_02125	COG2508	Transcriptional regulator
D9C08_02130	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_02135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C08_02150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9C08_02165	COG2197	response regulator
D9C08_02170	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C08_02180	COG4894	glucomannan catabolic process
D9C08_02185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C08_02190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C08_02195	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_02200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C08_02205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C08_02210	COG2610	gluconate transmembrane transporter activity
D9C08_02215	COG0500	methyltransferase
D9C08_02220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C08_02235	COG0693	protein deglycase activity
D9C08_02235	COG0753	catalase activity
D9C08_02240	COG2851	Citrate transporter
D9C08_02245	COG2273	Hydrolase Family 16
D9C08_02250	COG3711	transcriptional antiterminator
D9C08_02260	COG2270	Major facilitator Superfamily
D9C08_02265	COG0513	Belongs to the DEAD box helicase family
D9C08_02270	COG3401	FG-GAP repeat protein
D9C08_02270	COG2755	lipolytic protein G-D-S-L family
D9C08_02400	COG0589	response to stress
D9C08_02420	COG5444	nuclease activity
D9C08_02440	COG0494	nUDIX hydrolase
D9C08_02445	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
D9C08_02450	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C08_02465	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9C08_02470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C08_02475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9C08_02490	COG3192	ethanolamine utilization protein
D9C08_02495	COG2079	MmgE PrpD family protein
D9C08_02505	COG1126	abc transporter atp-binding protein
D9C08_02510	COG0765	amino acid transport
D9C08_02515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C08_02530	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9C08_02535	COG0561	phosphatase activity
D9C08_02575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C08_02580	COG5294	Protein conserved in bacteria
D9C08_02585	COG0577	efflux transmembrane transporter activity
D9C08_02590	COG1136	(ABC) transporter
D9C08_02595	COG2205	protein histidine kinase activity
D9C08_02600	COG0745	RESPONSE REGULATOR receiver
D9C08_02605	COG0191	fructose-bisphosphate aldolase activity
D9C08_02610	COG1082	Xylose isomerase domain protein TIM barrel
D9C08_02615	COG1082	Xylose isomerase domain protein TIM barrel
D9C08_02620	COG0673	inositol 2-dehydrogenase activity
D9C08_02625	COG2814	Major facilitator Superfamily
D9C08_02630	COG1082	Xylose isomerase domain protein TIM barrel
D9C08_02635	COG3962	Belongs to the TPP enzyme family
D9C08_02640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C08_02655	COG1349	DNA-binding transcription factor activity
D9C08_02660	COG0667	Aldo Keto reductase
D9C08_02690	COG0326	Molecular chaperone. Has ATPase activity
D9C08_02705	COG1309	transcriptional regulator
D9C08_02710	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_02715	COG1714	RDD family
D9C08_02725	COG1714	RDD family
D9C08_02730	COG2311	Membrane
D9C08_02735	COG1917	Cupin 2, conserved barrel domain protein
D9C08_02740	COG1309	transcriptional regulator
D9C08_02745	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_02750	COG1846	Transcriptional regulator
D9C08_02755	COG1380	Effector of murein hydrolase LrgA
D9C08_02760	COG1346	cytolysis
D9C08_02765	COG5039	Polysaccharide pyruvyl transferase
D9C08_02770	COG1929	Belongs to the glycerate kinase type-1 family
D9C08_02775	COG1802	Transcriptional regulator
D9C08_02780	COG1070	Carbohydrate kinase
D9C08_02785	COG2610	gluconate transmembrane transporter activity
D9C08_02790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C08_02795	COG0450	alkyl hydroperoxide reductase
D9C08_02800	COG3634	alkyl hydroperoxide reductase activity
D9C08_02805	COG2723	6-phospho-beta-galactosidase activity
D9C08_02810	COG2190	(PTS) system
D9C08_02820	COG2188	Transcriptional regulator
D9C08_02830	COG1131	(ABC) transporter
D9C08_02835	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D9C08_02850	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C08_02885	COG0210	DNA helicase
D9C08_02930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9C08_02945	COG1063	alcohol dehydrogenase
D9C08_02970	COG0456	acetyltransferase
D9C08_02990	COG0010	Belongs to the arginase family
D9C08_02995	COG0833	amino acid
D9C08_03000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C08_03020	COG5658	integral membrane protein
D9C08_03025	COG0640	Transcriptional regulator
D9C08_03030	COG3829	transcription factor binding
D9C08_03045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C08_03050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9C08_03055	COG4853	Protein conserved in bacteria
D9C08_03060	COG4863	YycH protein
D9C08_03065	COG5002	protein histidine kinase activity
D9C08_03070	COG0745	RESPONSE REGULATOR receiver
D9C08_03100	COG0346	lactoylglutathione lyase activity
D9C08_03105	COG0305	Participates in initiation and elongation during chromosome replication
D9C08_03120	COG3093	addiction module antidote protein HigA
D9C08_03125	COG2807	transmembrane transport
D9C08_03130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C08_03135	COG0359	binds to the 23S rRNA
D9C08_03140	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9C08_03160	COG1733	regulation of RNA biosynthetic process
D9C08_03165	COG1227	inorganic diphosphatase activity
D9C08_03185	COG4978	Transcriptional regulator
D9C08_03185	COG0789	Transcriptional regulator
D9C08_03195	COG4319	ketosteroid isomerase
D9C08_03200	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C08_03215	COG1846	Transcriptional regulator
D9C08_03220	COG2153	protein acetylation
D9C08_03225	COG2364	Membrane
D9C08_03240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C08_03250	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D9C08_03255	COG1331	Highly conserved protein containing a thioredoxin domain
D9C08_03260	COG1266	CAAX protease self-immunity
D9C08_03265	COG0477	Major facilitator Superfamily
D9C08_03265	COG2814	Major facilitator Superfamily
D9C08_03270	COG0110	maltose O-acetyltransferase activity
D9C08_03275	COG0346	lactoylglutathione lyase activity
D9C08_03285	COG0708	Exodeoxyribonuclease III
D9C08_03290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9C08_03295	COG0629	single-stranded DNA binding
D9C08_03300	COG0360	Binds together with S18 to 16S ribosomal RNA
D9C08_03305	COG0012	GTP binding
D9C08_03310	COG0243	molybdopterin cofactor binding
D9C08_03315	COG4481	Protein conserved in bacteria
D9C08_03320	COG3949	Membrane
D9C08_03335	COG1475	DNA binding
D9C08_03340	COG1192	Involved in chromosome partitioning
D9C08_03350	COG1475	DNA binding
D9C08_03355	COG0357	Ribosomal RNA small subunit methyltransferase G
D9C08_03360	COG0445	tRNA wobble uridine modification
D9C08_03365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9C08_03370	COG1847	R3H domain protein
D9C08_03375	COG0706	membrane insertase activity
D9C08_03380	COG0594	ribonuclease P activity
D9C08_03385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D9C08_03390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9C08_03395	COG0592	DNA-directed DNA polymerase activity
D9C08_03400	COG2501	S4 domain
D9C08_03405	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9C08_03415	COG0187	DNA topoisomerase II activity
D9C08_03420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C08_03455	COG0517	IMP dehydrogenase activity
D9C08_03455	COG0516	GMP reductase activity
D9C08_03460	COG1686	Belongs to the peptidase S11 family
D9C08_03465	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9C08_03470	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9C08_03475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9C08_03485	COG1428	Deoxynucleoside kinase
D9C08_03490	COG1428	Deoxynucleoside kinase
D9C08_03495	COG1388	LysM domain
D9C08_03495	COG3858	chitin binding
D9C08_03500	COG1335	isochorismatase
D9C08_03505	COG0590	tRNA wobble adenosine to inosine editing
D9C08_03515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9C08_03520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9C08_03525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9C08_03570	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9C08_03575	COG3853	Toxic anion resistance protein (TelA)
D9C08_03580	COG1982	Orn Lys Arg decarboxylase major
D9C08_03585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C08_03590	COG3870	Protein conserved in bacteria
D9C08_03595	COG1728	Protein conserved in bacteria
D9C08_03600	COG0470	DNA polymerase III
D9C08_03605	COG1774	PSP1 C-terminal conserved region
D9C08_03610	COG4467	Involved in initiation control of chromosome replication
D9C08_03615	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9C08_03620	COG2827	Endonuclease containing a URI domain
D9C08_03625	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9C08_03630	COG2002	toxin-antitoxin pair type II binding
D9C08_03635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C08_03635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C08_03640	COG0084	hydrolase, TatD family'
D9C08_03645	COG3584	3D domain protein
D9C08_03645	COG3583	domain protein
D9C08_03650	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C08_03655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9C08_03665	COG4466	Protein conserved in bacteria
D9C08_03675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9C08_03680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C08_03685	COG0251	oxidation-reduction process
D9C08_03690	COG2088	sporulation resulting in formation of a cellular spore
D9C08_03695	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9C08_03700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9C08_03705	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9C08_03710	COG0193	aminoacyl-tRNA hydrolase activity
D9C08_03720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9C08_03725	COG2002	toxin-antitoxin pair type II binding
D9C08_03730	COG2244	polysaccharide biosynthetic process
D9C08_03735	COG3956	TIGRFAM MazG family protein
D9C08_03740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9C08_03755	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9C08_03760	COG1098	S1 RNA binding domain
D9C08_03775	COG2208	phosphoserine phosphatase activity
D9C08_03780	COG2304	oxidoreductase activity
D9C08_03785	COG0515	serine threonine protein kinase
D9C08_03790	COG0037	tRNA processing
D9C08_03800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C08_03805	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9C08_03810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9C08_03815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C08_03820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C08_03835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C08_03840	COG0512	Glutamine amidotransferase of anthranilate synthase
D9C08_03845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C08_03850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9C08_03855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9C08_03860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9C08_03865	COG1396	sequence-specific DNA binding
D9C08_03870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C08_03875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9C08_03955	COG4463	regulation of RNA biosynthetic process
D9C08_03960	COG3880	PFAM UvrB UvrC protein
D9C08_03965	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9C08_03970	COG0542	response to heat
D9C08_03975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9C08_03980	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9C08_03985	COG4956	integral membrane protein (PIN domain superfamily)
D9C08_03990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9C08_03995	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9C08_04000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9C08_04005	COG1045	serine acetyltransferase
D9C08_04010	COG0215	cysteine-tRNA ligase activity
D9C08_04015	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9C08_04020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C08_04025	COG3688	RNA-binding protein containing a PIN domain
D9C08_04030	COG1595	DNA-templated transcription, initiation
D9C08_04035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C08_04040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C08_04045	COG0250	Participates in transcription elongation, termination and antitermination
D9C08_04050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9C08_04055	COG0081	regulation of translation
D9C08_04060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9C08_04065	COG0222	ribosome binding
D9C08_04070	COG2813	Specifically methylates the guanine in position
D9C08_04075	COG0085	RNA polymerase activity
D9C08_04080	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9C08_04085	COG1358	cellular component organization or biogenesis
D9C08_04090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9C08_04095	COG0049	tRNA binding
D9C08_04100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9C08_04105	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9C08_04110	COG0596	Alpha beta hydrolase
D9C08_04115	COG0051	transcription antitermination factor activity, RNA binding
D9C08_04120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9C08_04125	COG0088	Forms part of the polypeptide exit tunnel
D9C08_04130	COG0089	rRNA binding
D9C08_04135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9C08_04140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9C08_04145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9C08_04150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9C08_04155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9C08_04160	COG0255	Belongs to the universal ribosomal protein uL29 family
D9C08_04165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9C08_04170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9C08_04180	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9C08_04190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9C08_04195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9C08_04200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9C08_04205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9C08_04210	COG1841	ribosomal large subunit assembly
D9C08_04215	COG0200	Binds to the 23S rRNA
D9C08_04220	COG0201	protein transport
D9C08_04225	COG0563	adenylate kinase activity
D9C08_04230	COG0024	Methionine aminopeptidase
D9C08_04235	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9C08_04240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9C08_04245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9C08_04250	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9C08_04255	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9C08_04260	COG0202	RNA polymerase activity
D9C08_04265	COG0203	ribosomal protein L17
D9C08_04270	COG1122	ATPase activity
D9C08_04275	COG1122	ATPase activity
D9C08_04280	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C08_04285	COG0101	tRNA pseudouridine synthase activity
D9C08_04290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9C08_04295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9C08_04300	COG2226	methyltransferase
D9C08_04310	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C08_04315	COG0489	protein tyrosine kinase activity
D9C08_04325	COG2194	sulfuric ester hydrolase activity
D9C08_04330	COG0726	polysaccharide deacetylase
D9C08_04460	COG0659	secondary active sulfate transmembrane transporter activity
D9C08_04465	COG0385	Bile acid
D9C08_04470	COG2819	hydrolase of the alpha beta superfamily
D9C08_04475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_04480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_04485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C08_04490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C08_04490	COG2207	Transcriptional regulator
D9C08_04500	COG1472	Belongs to the glycosyl hydrolase 3 family
D9C08_04505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C08_04510	COG1263	PTS System
D9C08_04510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_04515	COG1737	Transcriptional regulator
D9C08_04520	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9C08_04525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_04530	COG1683	Conserved Protein
D9C08_04560	COG1595	DNA-templated transcription, initiation
D9C08_04565	COG5662	AntiSigma factor
D9C08_04570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C08_04575	COG4856	YbbR-like protein
D9C08_04580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C08_04585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9C08_04615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C08_04620	COG3002	Belongs to the UPF0753 family
D9C08_04625	COG0288	reversible hydration of carbon dioxide
D9C08_04635	COG5609	conserved protein (DUF2294)
D9C08_04655	COG0515	serine threonine protein kinase
D9C08_04670	COG1113	amino acid transport
D9C08_04690	COG2602	Beta-lactamase
D9C08_04695	COG2124	cytochrome p450
D9C08_04705	COG0531	amino acid
D9C08_04710	COG0584	glycerophosphoryl diester phosphodiesterase
D9C08_04715	COG2271	Major facilitator Superfamily
D9C08_04730	COG1846	Transcriptional regulator
D9C08_04730	COG0456	acetyltransferase
D9C08_04750	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_04760	COG1917	Cupin 2, conserved barrel domain protein
D9C08_04760	COG2207	Transcriptional regulator
D9C08_04785	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9C08_04790	COG3591	Belongs to the peptidase S1B family
D9C08_04800	COG0596	Alpha beta hydrolase
D9C08_04805	COG1183	phosphatidylcholine synthase activity
D9C08_04810	COG0586	Pfam SNARE associated Golgi protein
D9C08_04815	COG0688	phosphatidylethanolamine metabolic process
D9C08_04825	COG2312	Erythromycin esterase
D9C08_04830	COG2207	Transcriptional regulator
D9C08_04840	COG1301	dicarboxylic acid transport
D9C08_04845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_04845	COG2190	(PTS) system
D9C08_04845	COG1263	PTS System
D9C08_04850	COG0363	glucosamine-6-phosphate deaminase activity
D9C08_04865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C08_04870	COG0833	amino acid
D9C08_04875	COG2040	homocysteine
D9C08_04890	COG2066	Belongs to the glutaminase family
D9C08_04895	COG4191	Histidine kinase
D9C08_04900	COG0784	Response regulator, receiver
D9C08_04910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C08_04915	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_04920	COG2271	Major facilitator Superfamily
D9C08_04925	COG4948	Mandelate Racemase Muconate Lactonizing
D9C08_04930	COG2186	Transcriptional regulator
D9C08_04935	COG2721	sulfolactate sulfo-lyase activity
D9C08_04940	COG3173	Aminoglycoside phosphotransferase
D9C08_04950	COG0697	spore germination
D9C08_04955	COG0745	RESPONSE REGULATOR receiver
D9C08_04960	COG2205	protein histidine kinase activity
D9C08_04965	COG1131	(ABC) transporter
D9C08_04985	COG3773	Cell wall hydrolase
D9C08_04995	COG2304	oxidoreductase activity
D9C08_05005	COG3540	Alkaline phosphatase
D9C08_05010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C08_05015	COG0805	protein transport
D9C08_05020	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D9C08_05025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C08_05030	COG0477	Major facilitator Superfamily
D9C08_05035	COG1309	transcriptional regulator
D9C08_05040	COG0252	asparaginase activity
D9C08_05045	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C08_05050	COG1714	RDD family
D9C08_05055	COG1405	negative regulation of cell septum assembly
D9C08_05055	COG3012	SEC-C Motif Domain Protein
D9C08_05060	COG3290	protein histidine kinase activity
D9C08_05065	COG3279	Response regulator of the LytR AlgR family
D9C08_05070	COG4555	ABC transporter
D9C08_05075	COG1668	transmembrane transport
D9C08_05100	COG1595	DNA-templated transcription, initiation
D9C08_05105	COG1595	DNA-templated transcription, initiation
D9C08_05110	COG1876	peptidase activity
D9C08_05115	COG0457	Tetratricopeptide repeat
D9C08_05120	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_05125	COG0366	Alpha amylase catalytic
D9C08_05130	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C08_05135	COG1121	(ABC) transporter
D9C08_05140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C08_05160	COG2310	stress, protein
D9C08_05165	COG2310	stress, protein
D9C08_05170	COG2310	stress, protein
D9C08_05175	COG0861	Integral membrane protein TerC family
D9C08_05185	COG3853	Toxic anion resistance protein (TelA)
D9C08_05190	COG0477	Major facilitator Superfamily
D9C08_05200	COG2814	Major facilitator Superfamily
D9C08_05205	COG0640	Transcriptional regulator
D9C08_05210	COG0517	IMP dehydrogenase activity
D9C08_05210	COG4175	Glycine betaine
D9C08_05215	COG4176	ABC-type proline glycine betaine transport system permease component
D9C08_05220	COG2113	Glycine betaine
D9C08_05225	COG1473	amidohydrolase
D9C08_05230	COG1288	antiporter activity
D9C08_05245	COG0039	L-malate dehydrogenase activity
D9C08_05250	COG1620	l-lactate permease
D9C08_05260	COG3403	YqcI/YcgG family
D9C08_05270	COG3665	Urea carboxylase-associated protein
D9C08_05275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9C08_05280	COG1660	Displays ATPase and GTPase activities
D9C08_05290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9C08_05295	COG2226	methyltransferase
D9C08_05300	COG0583	DNA-binding transcription factor activity
D9C08_05305	COG3458	cephalosporin-C deacetylase activity
D9C08_05310	COG3541	Predicted nucleotidyltransferase
D9C08_05315	COG0506	proline dehydrogenase activity
D9C08_05320	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_05325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C08_05330	COG2508	Transcriptional regulator
D9C08_05335	COG3689	TIGRFAM TIGR03943 family protein
D9C08_05340	COG0701	Predicted permease
D9C08_05345	COG2267	carboxylic ester hydrolase activity
D9C08_05350	COG0492	ferredoxin-NADP+ reductase activity
D9C08_05355	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C08_05355	COG1587	Uroporphyrinogen-III synthase
D9C08_05360	COG2146	nitrite reductase [NAD(P)H] activity
D9C08_05365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C08_05370	COG0243	molybdopterin cofactor binding
D9C08_05375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C08_05380	COG2223	nitrite transmembrane transporter activity
D9C08_05390	COG1376	ErfK ybiS ycfS ynhG family protein
D9C08_05405	COG0765	amino acid transport
D9C08_05410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C08_05420	COG1714	RDD family
D9C08_05430	COG1846	Transcriptional regulator
D9C08_05445	COG2723	6-phospho-beta-galactosidase activity
D9C08_05455	COG3209	COG3209 Rhs family protein
D9C08_05465	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9C08_05470	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9C08_05475	COG1733	regulation of RNA biosynthetic process
D9C08_05480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C08_05485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C08_05490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C08_05495	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9C08_05500	COG2814	Major facilitator Superfamily
D9C08_05510	COG0697	spore germination
D9C08_05520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C08_05530	COG2364	Membrane
D9C08_05535	COG1126	abc transporter atp-binding protein
D9C08_05540	COG0765	amino acid transport
D9C08_05545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C08_05550	COG0583	DNA-binding transcription factor activity
D9C08_05555	COG0163	prenyltransferase activity
D9C08_05560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9C08_05575	COG0596	Alpha beta hydrolase
D9C08_05580	COG3104	oligopeptide transport
D9C08_05585	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C08_05600	COG0697	spore germination
D9C08_05610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C08_05615	COG1136	(ABC) transporter
D9C08_05620	COG0577	efflux transmembrane transporter activity
D9C08_05625	COG0745	RESPONSE REGULATOR receiver
D9C08_05630	COG3850	Histidine kinase
D9C08_05630	COG5002	protein histidine kinase activity
D9C08_05635	COG0457	Tetratricopeptide repeat
D9C08_05655	COG0527	aspartate kinase activity
D9C08_05660	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_05665	COG4605	iron ion homeostasis
D9C08_05670	COG4604	ABC transporter, ATP-binding protein
D9C08_05675	COG4607	ABC-type enterochelin transport system periplasmic component
D9C08_05680	COG2814	Major facilitator Superfamily
D9C08_05685	COG1309	transcriptional regulator
D9C08_05690	COG0778	Nitroreductase
D9C08_05695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C08_05700	COG0640	Transcriptional regulator
D9C08_05705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C08_05710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9C08_05715	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_05720	COG4975	Glucose uptake
D9C08_05725	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_05730	COG4549	nuclear export factor GLE1
D9C08_05735	COG1276	copper resistance
D9C08_05735	COG2372	response to copper ion
D9C08_05740	COG1349	DNA-binding transcription factor activity
D9C08_05750	COG2213	PTS system mannitol-specific
D9C08_05755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_05760	COG0246	Mannitol dehydrogenase
D9C08_05765	COG0473	3-isopropylmalate dehydrogenase activity
D9C08_05770	COG0681	Belongs to the peptidase S26 family
D9C08_05780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C08_05795	COG0561	phosphatase activity
D9C08_05800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9C08_05805	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C08_05810	COG4336	lyase activity
D9C08_05815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9C08_05820	COG1984	allophanate hydrolase subunit 2
D9C08_05825	COG1414	Transcriptional regulator
D9C08_05830	COG2755	lipolytic protein G-D-S-L family
D9C08_05840	COG2329	Antibiotic biosynthesis monooxygenase
D9C08_05845	COG0768	penicillin binding
D9C08_05850	COG4989	oxidoreductase activity
D9C08_05855	COG3711	transcriptional antiterminator
D9C08_05860	COG0318	PFAM AMP-dependent synthetase and ligase
D9C08_05865	COG2226	methyltransferase
D9C08_05870	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_05875	COG1917	Cupin 2, conserved barrel domain protein
D9C08_05880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_05885	COG3871	stress protein (general stress protein 26)
D9C08_05895	COG2814	Major facilitator Superfamily
D9C08_05900	COG1522	sequence-specific DNA binding
D9C08_05905	COG0551	DNA topoisomerase type I activity
D9C08_05905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C08_05910	COG0494	nUDIX hydrolase
D9C08_05915	COG0028	Belongs to the TPP enzyme family
D9C08_05940	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C08_05945	COG2261	transglycosylase associated protein
D9C08_05950	COG4876	unkown
D9C08_05955	COG2217	Heavy metal translocating P-type atpase
D9C08_05960	COG3729	General stress protein
D9C08_05965	COG0662	Cupin 2, conserved barrel domain protein
D9C08_05970	COG2329	Antibiotic biosynthesis monooxygenase
D9C08_05975	COG3546	catalase activity
D9C08_05980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9C08_05985	COG3290	protein histidine kinase activity
D9C08_05990	COG4565	transcriptional regulatory protein
D9C08_05995	COG1301	dicarboxylic acid transport
D9C08_06000	COG0628	permease
D9C08_06005	COG1131	(ABC) transporter
D9C08_06010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C08_06020	COG1960	acyl-CoA dehydrogenase activity
D9C08_06035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C08_06040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_06045	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9C08_06050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9C08_06060	COG0513	Belongs to the DEAD box helicase family
D9C08_06065	COG3402	PFAM membrane-flanked domain
D9C08_06070	COG3428	Bacterial PH domain
D9C08_06075	COG0705	Rhomboid family
D9C08_06080	COG0736	holo-[acyl-carrier-protein] synthase activity
D9C08_06085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9C08_06090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C08_06095	COG0864	Transcriptional regulator
D9C08_06100	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9C08_06105	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_06110	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_06115	COG2172	sigma factor antagonist activity
D9C08_06120	COG2208	phosphoserine phosphatase activity
D9C08_06125	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_06130	COG2172	sigma factor antagonist activity
D9C08_06135	COG1191	sigma factor activity
D9C08_06140	COG2208	phosphoserine phosphatase activity
D9C08_06145	COG2183	response to ionizing radiation
D9C08_06155	COG3091	SprT-like family
D9C08_06205	COG0583	DNA-binding transcription factor activity
D9C08_06210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_06220	COG5444	nuclease activity
D9C08_06230	COG1476	TRANSCRIPTIONal
D9C08_06255	COG0693	protein deglycase activity
D9C08_06260	COG1278	Cold shock
D9C08_06265	COG1329	Transcriptional regulator
D9C08_06285	COG0697	spore germination
D9C08_06290	COG1917	Cupin 2, conserved barrel domain protein
D9C08_06290	COG2207	Transcriptional regulator
D9C08_06295	COG0697	spore germination
D9C08_06300	COG3708	Transcriptional regulator
D9C08_06300	COG2207	Transcriptional regulator
D9C08_06305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C08_06315	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D9C08_06335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_06340	COG1309	transcriptional regulator
D9C08_06345	COG0697	spore germination
D9C08_06350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C08_06355	COG2030	dehydratase
D9C08_06360	COG3545	Serine hydrolase
D9C08_06365	COG1733	regulation of RNA biosynthetic process
D9C08_06370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C08_06375	COG0640	Transcriptional regulator
D9C08_06380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C08_06390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_06395	COG0697	spore germination
D9C08_06400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C08_06405	COG0076	glutamate decarboxylase activity
D9C08_06410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C08_06415	COG0640	Transcriptional regulator
D9C08_06435	COG4585	Histidine kinase
D9C08_06440	COG2197	response regulator
D9C08_06445	COG2409	Drug exporters of the RND superfamily
D9C08_06460	COG0596	Alpha beta hydrolase
D9C08_06465	COG1811	Na channel or pump
D9C08_06470	COG0789	Transcriptional regulator
D9C08_06470	COG4978	Transcriptional regulator
D9C08_06475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C08_06480	COG0778	Nitroreductase
D9C08_06485	COG0346	lactoylglutathione lyase activity
D9C08_06490	COG2259	Doxx family
D9C08_06495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_06510	COG2323	membrane
D9C08_06515	COG2323	membrane
D9C08_06520	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C08_06535	COG1309	transcriptional regulator
D9C08_06545	COG0456	acetyltransferase
D9C08_06555	COG1113	amino acid transport
D9C08_06560	COG2318	DinB family
D9C08_06565	COG1846	Transcriptional regulator
D9C08_06570	COG1033	growth of symbiont in host cell
D9C08_06570	COG2409	Drug exporters of the RND superfamily
D9C08_06575	COG0778	Nitroreductase
D9C08_06580	COG1846	Transcriptional regulator
D9C08_06585	COG2814	Major facilitator Superfamily
D9C08_06590	COG0730	response to heat
D9C08_06595	COG1802	Transcriptional regulator
D9C08_06600	COG3858	chitin binding
D9C08_06600	COG1388	LysM domain
D9C08_06605	COG1819	glycosyl
D9C08_06615	COG1785	Belongs to the alkaline phosphatase family
D9C08_06620	COG5646	InterPro IPR014922
D9C08_06630	COG0454	-acetyltransferase
D9C08_06635	COG1078	dGTPase activity
D9C08_06640	COG1388	LysM domain
D9C08_06645	COG2814	Major facilitator Superfamily
D9C08_06650	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C08_06665	COG2723	6-phospho-beta-galactosidase activity
D9C08_06670	COG2188	Transcriptional regulator
D9C08_06675	COG1940	carbohydrate kinase activity
D9C08_06685	COG4124	Belongs to the glycosyl hydrolase 26 family
D9C08_06730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9C08_06735	COG0802	atpase or kinase
D9C08_06740	COG1214	PFAM Peptidase M22, glycoprotease
D9C08_06745	COG0456	acetyltransferase
D9C08_06750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9C08_06760	COG0488	(ABC) transporter
D9C08_06765	COG0315	cyclic pyranopterin monophosphate synthase activity
D9C08_06770	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9C08_06775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C08_06780	COG0805	protein transport
D9C08_06795	COG1266	CAAX protease self-immunity
D9C08_06800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9C08_06805	COG0459	protein refolding
D9C08_06810	COG4974	Belongs to the 'phage' integrase family
D9C08_06815	COG2856	Zn peptidase
D9C08_06820	COG1396	sequence-specific DNA binding
D9C08_06880	COG3935	DnaD domain protein
D9C08_06885	COG1484	DNA-dependent DNA replication
D9C08_06890	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D9C08_06930	COG3677	Transposase
D9C08_07020	COG3953	SLT domain
D9C08_07020	COG5280	Phage tail tape measure protein TP901
D9C08_07030	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C08_07065	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_07065	COG1388	LysM domain
D9C08_07065	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C08_07075	COG5444	nuclease activity
D9C08_07125	COG0457	Tetratricopeptide repeat
D9C08_07130	COG1063	alcohol dehydrogenase
D9C08_07135	COG2211	Major facilitator Superfamily
D9C08_07140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C08_07145	COG1842	Phage shock protein A
D9C08_07150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C08_07155	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D9C08_07160	COG4260	virion core protein, lumpy skin disease virus
D9C08_07170	COG2814	Major facilitator Superfamily
D9C08_07175	COG1063	alcohol dehydrogenase
D9C08_07180	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9C08_07185	COG0823	Involved in the tonB-independent uptake of proteins
D9C08_07205	COG2267	carboxylic ester hydrolase activity
D9C08_07215	COG2132	Multicopper oxidase
D9C08_07220	COG1113	amino acid transport
D9C08_07230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C08_07235	COG0714	Associated with various cellular activities
D9C08_07240	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9C08_07245	COG1305	Transglutaminase-like
D9C08_07250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9C08_07250	COG0519	Catalyzes the synthesis of GMP from XMP
D9C08_07265	COG2252	PERMEase
D9C08_07270	COG3064	Membrane
D9C08_07285	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9C08_07295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9C08_07300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9C08_07305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9C08_07310	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9C08_07315	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C08_07320	COG0047	phosphoribosylformylglycinamidine synthase activity
D9C08_07325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C08_07330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9C08_07335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9C08_07340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9C08_07345	COG0138	bifunctional purine biosynthesis protein purh
D9C08_07350	COG0151	Belongs to the GarS family
D9C08_07355	COG1522	sequence-specific DNA binding
D9C08_07370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C08_07375	COG1470	cell adhesion involved in biofilm formation
D9C08_07380	COG4496	protein, YerC YecD
D9C08_07385	COG0069	glutamate synthase activity
D9C08_07390	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9C08_07395	COG0210	DNA helicase
D9C08_07400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9C08_07405	COG4851	CamS sex pheromone cAM373 precursor
D9C08_07410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C08_07415	COG1285	pathogenesis
D9C08_07420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C08_07425	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C08_07430	COG0154	amidase activity
D9C08_07435	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C08_07440	COG1309	transcriptional regulator
D9C08_07445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9C08_07450	COG1597	lipid kinase activity
D9C08_07455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C08_07485	COG0457	Tetratricopeptide repeat
D9C08_07505	COG5444	nuclease activity
D9C08_07515	COG3586	endonuclease activity
D9C08_07525	COG0457	Tetratricopeptide repeat
D9C08_07535	COG0217	transcriptional regulatory protein
D9C08_07545	COG1309	transcriptional regulator
D9C08_07550	COG3631	Ketosteroid isomerase-related protein
D9C08_07555	COG0702	epimerase
D9C08_07570	COG3546	catalase activity
D9C08_07575	COG0454	-acetyltransferase
D9C08_07585	COG5578	integral membrane protein
D9C08_07590	COG2972	Histidine kinase
D9C08_07600	COG1653	transport
D9C08_07610	COG0395	ABC-type sugar transport system, permease component
D9C08_07615	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C08_07620	COG2207	Transcriptional regulator
D9C08_07625	COG2755	lipolytic protein G-D-S-L family
D9C08_07635	COG5578	integral membrane protein
D9C08_07645	COG3401	FG-GAP repeat protein
D9C08_07655	COG1874	Beta-galactosidase
D9C08_07665	COG1653	transport
D9C08_07670	COG4209	transmembrane transport
D9C08_07675	COG0395	ABC-type sugar transport system, permease component
D9C08_07680	COG1486	melibiose metabolic process
D9C08_07685	COG2323	membrane
D9C08_07690	COG2329	Antibiotic biosynthesis monooxygenase
D9C08_07695	COG0346	lactoylglutathione lyase activity
D9C08_07710	COG5583	Uncharacterized small protein (DUF2292)
D9C08_07715	COG0670	Belongs to the BI1 family
D9C08_07720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C08_07725	COG1715	Restriction endonuclease
D9C08_07735	COG2124	cytochrome p450
D9C08_07735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C08_07740	COG1368	sulfuric ester hydrolase activity
D9C08_07745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9C08_07750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C08_07760	COG1216	Glycosyl transferase, family 2
D9C08_07765	COG1442	glycosyl transferase family 8
D9C08_07770	COG2223	nitrite transmembrane transporter activity
D9C08_07775	COG1011	Hydrolase
D9C08_07780	COG0531	amino acid
D9C08_07785	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_07790	COG0840	transmembrane signaling receptor activity
D9C08_07795	COG0488	(ABC) transporter
D9C08_07805	COG0789	Transcriptional regulator
D9C08_07810	COG2814	Major facilitator Superfamily
D9C08_07830	COG0488	(ABC) transporter
D9C08_07835	COG0513	Belongs to the DEAD box helicase family
D9C08_07840	COG0456	acetyltransferase
D9C08_07845	COG3328	transposase activity
D9C08_07855	COG2130	NADP-dependent
D9C08_07860	COG1120	ATPase activity
D9C08_07865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_07870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_07875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C08_07890	COG3866	Pectate lyase
D9C08_07895	COG0471	metal ion transport
D9C08_07900	COG3290	protein histidine kinase activity
D9C08_07905	COG4565	transcriptional regulatory protein
D9C08_07910	COG3181	Tripartite tricarboxylate transporter family receptor
D9C08_07915	COG2851	Citrate transporter
D9C08_07920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C08_07925	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9C08_07930	COG1254	Belongs to the acylphosphatase family
D9C08_07935	COG2258	MOSC domain
D9C08_07955	COG0024	Methionine aminopeptidase
D9C08_07960	COG1263	PTS System
D9C08_07960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_07965	COG1368	sulfuric ester hydrolase activity
D9C08_07990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_07990	COG1263	PTS System
D9C08_07995	COG0366	Alpha amylase catalytic
D9C08_08000	COG2188	Transcriptional regulator
D9C08_08005	COG0778	Nitroreductase
D9C08_08010	COG0737	Belongs to the 5'-nucleotidase family
D9C08_08015	COG0693	protein deglycase activity
D9C08_08020	COG2814	Major facilitator Superfamily
D9C08_08025	COG4840	Belongs to the UPF0435 family
D9C08_08030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C08_08035	COG4980	gas vesicle protein
D9C08_08040	COG1295	ribonuclease BN
D9C08_08045	COG0477	Major facilitator Superfamily
D9C08_08050	COG0387	Pfam Sodium calcium exchanger
D9C08_08060	COG0668	transmembrane transport
D9C08_08065	COG0535	radical SAM domain protein
D9C08_08075	COG0726	polysaccharide deacetylase
D9C08_08080	COG2084	Dehydrogenase
D9C08_08085	COG0598	Magnesium transport protein CorA
D9C08_08090	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C08_08095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C08_08105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C08_08110	COG4637	Psort location Cytoplasmic, score
D9C08_08120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C08_08125	COG0022	dehydrogenase e1 component
D9C08_08130	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C08_08135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C08_08140	COG3284	Transcriptional regulator
D9C08_08150	COG1742	UPF0060 membrane protein
D9C08_08175	COG4842	Belongs to the WXG100 family
D9C08_08180	COG1486	melibiose metabolic process
D9C08_08185	COG1737	Transcriptional regulator
D9C08_08190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_08190	COG1263	PTS System
D9C08_08195	COG1132	(ABC) transporter
D9C08_08200	COG1132	(ABC) transporter
D9C08_08205	COG2259	Doxx family
D9C08_08210	COG2514	catechol 2,3-dioxygenase activity
D9C08_08215	COG4585	Histidine kinase
D9C08_08220	COG2197	response regulator
D9C08_08225	COG1131	(ABC) transporter
D9C08_08230	COG1511	domain protein
D9C08_08230	COG0842	Transport permease protein
D9C08_08235	COG0842	Transport permease protein
D9C08_08240	COG1695	Transcriptional regulator
D9C08_08245	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C08_08250	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9C08_08255	COG1309	transcriptional regulator
D9C08_08260	COG2814	Major facilitator Superfamily
D9C08_08265	COG2318	DinB family
D9C08_08275	COG1846	Transcriptional regulator
D9C08_08280	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9C08_08280	COG0392	lysyltransferase activity
D9C08_08285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C08_08290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_08295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_08300	COG0384	phenazine biosynthesis protein PhzF
D9C08_08305	COG0778	Nitroreductase
D9C08_08320	COG1090	epimerase
D9C08_08325	COG2137	regulation of response to DNA damage stimulus
D9C08_08335	COG2814	Major facilitator Superfamily
D9C08_08355	COG3103	Sh3 type 3 domain protein
D9C08_08360	COG5658	integral membrane protein
D9C08_08365	COG0596	Alpha beta hydrolase
D9C08_08370	COG0463	Glycosyl transferase, family 2
D9C08_08375	COG4485	Bacterial membrane protein, YfhO
D9C08_08380	COG1988	membrane-bound metal-dependent
D9C08_08385	COG1194	a g-specific adenine glycosylase
D9C08_08395	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_08410	COG3557	Belongs to the UPF0374 family
D9C08_08415	COG1132	(ABC) transporter
D9C08_08420	COG4129	membrane
D9C08_08425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C08_08430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9C08_08435	COG0735	belongs to the Fur family
D9C08_08560	COG4326	sporulation control protein
D9C08_08570	COG5577	PFAM Coat F domain
D9C08_08575	COG3340	Belongs to the peptidase S51 family
D9C08_08580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9C08_08595	COG0753	catalase activity
D9C08_08600	COG1116	anion transmembrane transporter activity
D9C08_08605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C08_08610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C08_08615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C08_08625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9C08_08635	COG1476	TRANSCRIPTIONal
D9C08_08645	COG3382	B3 4 domain protein
D9C08_08650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9C08_08660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9C08_08665	COG0789	Transcriptional regulator
D9C08_08670	COG1664	Polymer-forming cytoskeletal
D9C08_08675	COG1664	Polymer-forming cytoskeletal
D9C08_08680	COG2766	serine protein kinase
D9C08_08685	COG2718	Belongs to the UPF0229 family
D9C08_08690	COG1846	Transcriptional regulator
D9C08_08695	COG1566	PFAM secretion protein HlyD family protein
D9C08_08700	COG2814	Major facilitator Superfamily
D9C08_08705	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C08_08725	COG1725	Transcriptional regulator
D9C08_08730	COG1131	(ABC) transporter
D9C08_08735	COG1131	(ABC) transporter
D9C08_08740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C08_08745	COG1278	Cold shock
D9C08_08755	COG1464	Belongs to the NlpA lipoprotein family
D9C08_08760	COG3706	GGDEF domain
D9C08_08765	COG1823	symporter activity
D9C08_08770	COG5444	nuclease activity
D9C08_08795	COG0582	viral genome integration into host DNA
D9C08_08800	COG2946	Replication initiation factor
D9C08_08850	COG5644	endopeptidase inhibitor activity
D9C08_08855	COG0741	lytic transglycosylase activity
D9C08_08855	COG0791	NLP P60 protein
D9C08_08875	COG0457	Tetratricopeptide repeat
D9C08_08900	COG4085	toxin activity
D9C08_08900	COG1525	nuclease
D9C08_08900	COG0737	Belongs to the 5'-nucleotidase family
D9C08_08905	COG3764	Sortase (surface protein transpeptidase)
D9C08_08910	COG0564	pseudouridine synthase activity
D9C08_08920	COG0517	IMP dehydrogenase activity
D9C08_08925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C08_08930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C08_08930	COG3153	acetyltransferase
D9C08_08940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C08_08945	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9C08_08950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9C08_08955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9C08_08960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9C08_08965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C08_08970	COG2203	Gaf domain
D9C08_08970	COG4585	Histidine kinase
D9C08_08975	COG2197	response regulator
D9C08_08980	COG0431	NADPH-dependent FMN reductase
D9C08_08995	COG0791	NLP P60 protein
D9C08_08995	COG1388	LysM domain
D9C08_09000	COG1959	2 iron, 2 sulfur cluster binding
D9C08_09010	COG0668	transmembrane transport
D9C08_09015	COG2719	SpoVR family
D9C08_09020	COG1785	Belongs to the alkaline phosphatase family
D9C08_09025	COG0791	NLP P60 protein
D9C08_09025	COG1388	LysM domain
D9C08_09030	COG0583	DNA-binding transcription factor activity
D9C08_09035	COG0372	Belongs to the citrate synthase family
D9C08_09040	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_09050	COG0531	amino acid
D9C08_09055	COG0733	neurotransmitter:sodium symporter activity
D9C08_09060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C08_09065	COG0456	acetyltransferase
D9C08_09080	COG1595	DNA-templated transcription, initiation
D9C08_09085	COG0667	Aldo Keto reductase
D9C08_09090	COG0204	Acyl-transferase
D9C08_09095	COG1253	flavin adenine dinucleotide binding
D9C08_09100	COG0789	Transcriptional regulator
D9C08_09110	COG1253	flavin adenine dinucleotide binding
D9C08_09115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C08_09120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C08_09125	COG0584	glycerophosphoryl diester phosphodiesterase
D9C08_09135	COG0668	transmembrane transport
D9C08_09140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9C08_09145	COG0726	polysaccharide deacetylase
D9C08_09150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C08_09155	COG1757	Na H antiporter
D9C08_09160	COG0589	response to stress
D9C08_09170	COG1132	(ABC) transporter
D9C08_09175	COG1132	(ABC) transporter
D9C08_09180	COG0702	epimerase
D9C08_09200	COG0189	ligase activity
D9C08_09205	COG0189	ligase activity
D9C08_09210	COG4399	Belongs to the UPF0754 family
D9C08_09215	COG3679	Belongs to the UPF0342 family
D9C08_09225	COG0561	phosphatase activity
D9C08_09230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C08_09235	COG0475	glutathione-regulated potassium exporter activity
D9C08_09240	COG0490	domain, Protein
D9C08_09250	COG1024	Enoyl-CoA hydratase
D9C08_09260	COG4152	abc transporter atp-binding protein
D9C08_09265	COG1668	transmembrane transport
D9C08_09270	COG0420	3'-5' exonuclease activity
D9C08_09275	COG4717	serine-type aminopeptidase activity
D9C08_09280	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9C08_09290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C08_09320	COG1846	Transcriptional regulator
D9C08_09325	COG4980	gas vesicle protein
D9C08_09340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9C08_09345	COG0537	adenosine 5'-monophosphoramidase activity
D9C08_09350	COG1131	(ABC) transporter
D9C08_09355	COG4473	ABC transporter
D9C08_09365	COG1473	amidohydrolase
D9C08_09370	COG3069	C4-dicarboxylate transmembrane transporter activity
D9C08_09380	COG2329	Antibiotic biosynthesis monooxygenase
D9C08_09385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C08_09390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9C08_09405	COG1309	transcriptional regulator
D9C08_09410	COG1511	domain protein
D9C08_09425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C08_09430	COG4377	Putative membrane peptidase family (DUF2324)
D9C08_09440	COG1363	Peptidase, m42
D9C08_09445	COG4405	Protein conserved in bacteria
D9C08_09450	COG1301	dicarboxylic acid transport
D9C08_09460	COG1234	tRNA 3'-trailer cleavage
D9C08_09465	COG0095	Lipoate-protein ligase
D9C08_09470	COG0702	epimerase
D9C08_09475	COG0318	PFAM AMP-dependent synthetase and ligase
D9C08_09490	COG0501	Belongs to the peptidase M48B family
D9C08_09500	COG0456	acetyltransferase
D9C08_09505	COG0604	alcohol dehydrogenase
D9C08_09510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C08_09520	COG0406	alpha-ribazole phosphatase activity
D9C08_09525	COG0183	Belongs to the thiolase family
D9C08_09530	COG0318	PFAM AMP-dependent synthetase and ligase
D9C08_09535	COG1268	BioY protein
D9C08_09540	COG0840	transmembrane signaling receptor activity
D9C08_09550	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_09560	COG4903	ComK protein
D9C08_09565	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_09575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C08_09590	COG0398	Pfam SNARE associated Golgi protein
D9C08_09595	COG0681	Belongs to the peptidase S26 family
D9C08_09600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C08_09605	COG1846	Transcriptional regulator
D9C08_09625	COG0738	Major facilitator superfamily
D9C08_09630	COG0673	inositol 2-dehydrogenase activity
D9C08_09635	COG0561	phosphatase activity
D9C08_09640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C08_09645	COG1609	Transcriptional regulator
D9C08_09650	COG3180	Ammonia monooxygenase
D9C08_09655	COG2814	Major facilitator Superfamily
D9C08_09655	COG0477	Major facilitator Superfamily
D9C08_09660	COG4533	DNA binding
D9C08_09670	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9C08_09675	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9C08_09680	COG1074	ATP-dependent DNA helicase activity
D9C08_09685	COG0420	3'-5' exonuclease activity
D9C08_09690	COG0419	ATPase involved in DNA repair
D9C08_09695	COG1403	HNH endonuclease
D9C08_09735	COG5337	Spore coat protein CotH
D9C08_09740	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9C08_09750	COG1404	Belongs to the peptidase S8 family
D9C08_09765	COG0367	asparagine synthase
D9C08_09770	COG1562	ergosterol biosynthetic process
D9C08_09775	COG0534	Mate efflux family protein
D9C08_09780	COG1917	Cupin 2, conserved barrel domain protein
D9C08_09780	COG2207	Transcriptional regulator
D9C08_09785	COG1609	Transcriptional regulator
D9C08_09790	COG0673	inositol 2-dehydrogenase activity
D9C08_09795	COG2318	DinB family
D9C08_09800	COG1279	arginine transmembrane transporter activity
D9C08_09805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C08_09810	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C08_09815	COG2267	carboxylic ester hydrolase activity
D9C08_09825	COG2153	protein acetylation
D9C08_09830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9C08_09830	COG0646	methionine synthase
D9C08_09835	COG1666	GTP binding
D9C08_09840	COG2996	Protein conserved in bacteria
D9C08_09860	COG1695	Transcriptional regulator
D9C08_09875	COG3227	Zinc metalloprotease (Elastase)
D9C08_09880	COG1307	EDD domain protein, DegV family
D9C08_09885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C08_09900	COG0561	phosphatase activity
D9C08_09905	COG1073	alpha beta
D9C08_09910	COG2151	metal-sulfur cluster biosynthetic enzyme
D9C08_09920	COG0277	FAD linked oxidase domain protein
D9C08_09930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9C08_09945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C08_09950	COG0505	Belongs to the CarA family
D9C08_09955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C08_09960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9C08_09980	COG2267	carboxylic ester hydrolase activity
D9C08_09990	COG1744	ABC transporter substrate-binding protein PnrA-like
D9C08_10005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C08_10010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C08_10015	COG5504	Zn-dependent protease
D9C08_10020	COG0444	Belongs to the ABC transporter superfamily
D9C08_10025	COG4608	Belongs to the ABC transporter superfamily
D9C08_10035	COG0601	transmembrane transport
D9C08_10040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C08_10050	COG0180	Tryptophanyl-tRNA synthetase
D9C08_10055	COG4166	transmembrane transport
D9C08_10060	COG0601	transmembrane transport
D9C08_10065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C08_10070	COG0444	Belongs to the ABC transporter superfamily
D9C08_10075	COG4608	Belongs to the ABC transporter superfamily
D9C08_10080	COG2814	Major facilitator Superfamily
D9C08_10090	COG1393	Belongs to the ArsC family
D9C08_10095	COG0861	Integral membrane protein TerC family
D9C08_10105	COG4862	establishment of competence for transformation
D9C08_10115	COG4469	Competence protein
D9C08_10120	COG1164	Oligoendopeptidase f
D9C08_10140	COG2346	COG2346, Truncated hemoglobins
D9C08_10145	COG0741	lytic transglycosylase activity
D9C08_10150	COG4116	CYTH
D9C08_10160	COG2357	RelA SpoT domain protein
D9C08_10165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C08_10170	COG0564	pseudouridine synthase activity
D9C08_10175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9C08_10180	COG0475	glutathione-regulated potassium exporter activity
D9C08_10180	COG0569	domain protein
D9C08_10185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9C08_10190	COG0352	thiamine-phosphate diphosphorylase activity
D9C08_10195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C08_10200	COG2104	thiamine diphosphate biosynthetic process
D9C08_10205	COG2022	thiamine diphosphate biosynthetic process
D9C08_10210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C08_10215	COG0351	phosphomethylpyrimidine kinase
D9C08_10220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9C08_10275	COG0210	DNA helicase
D9C08_10285	COG2153	protein acetylation
D9C08_10290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C08_10295	COG2382	esterase
D9C08_10300	COG0626	cystathionine gamma-synthase activity
D9C08_10305	COG0626	cystathionine gamma-synthase activity
D9C08_10310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_10315	COG5505	Protein of unknown function (DUF819)
D9C08_10350	COG1396	sequence-specific DNA binding
D9C08_10475	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C08_10485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_10485	COG3711	transcriptional antiterminator
D9C08_10495	COG1482	cell wall glycoprotein biosynthetic process
D9C08_10510	COG3328	transposase activity
D9C08_10515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_10525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C08_10540	COG0109	protoheme IX farnesyltransferase activity
D9C08_10550	COG0726	polysaccharide deacetylase
D9C08_10570	COG2205	protein histidine kinase activity
D9C08_10580	COG3383	formate dehydrogenase (NAD+) activity
D9C08_10585	COG2427	Protein of unknown function (DUF1641)
D9C08_10595	COG1051	belongs to the nudix hydrolase family
D9C08_10605	COG2124	cytochrome p450
D9C08_10610	COG1819	glycosyl
D9C08_10620	COG1587	Uroporphyrinogen-III synthase
D9C08_10630	COG0390	transport system, permease component
D9C08_10635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C08_10640	COG0697	spore germination
D9C08_10655	COG1252	NADH dehydrogenase
D9C08_10660	COG1904	glucuronate isomerase
D9C08_10670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9C08_10675	COG1063	alcohol dehydrogenase
D9C08_10680	COG1312	Catalyzes the dehydration of D-mannonate
D9C08_10685	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_10690	COG2271	Major facilitator Superfamily
D9C08_10695	COG1609	Transcriptional regulator
D9C08_10700	COG0246	Mannitol dehydrogenase
D9C08_10705	COG2721	sulfolactate sulfo-lyase activity
D9C08_10710	COG0730	response to heat
D9C08_10720	COG2318	DinB family
D9C08_10740	COG0457	Tetratricopeptide repeat
D9C08_10755	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C08_10755	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_10755	COG1388	LysM domain
D9C08_10765	COG4195	phage-related replication protein
D9C08_10770	COG3546	catalase activity
D9C08_10775	COG2856	Zn peptidase
D9C08_10780	COG1396	sequence-specific DNA binding
D9C08_10790	COG1522	sequence-specific DNA binding
D9C08_10795	COG1484	DNA-dependent DNA replication
D9C08_10815	COG1595	DNA-templated transcription, initiation
D9C08_10820	COG3728	DNA packaging
D9C08_10820	COG5484	DNA packaging
D9C08_10825	COG1783	phage Terminase large subunit
D9C08_10830	COG5518	Phage portal protein
D9C08_10835	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9C08_10840	COG4653	Phage capsid family
D9C08_10890	COG3953	SLT domain
D9C08_10890	COG5412	phage tail tape measure protein
D9C08_10890	COG3953	SLT domain
D9C08_10890	COG5412	phage tail tape measure protein
D9C08_10890	COG3953	SLT domain
D9C08_10890	COG5412	phage tail tape measure protein
D9C08_10895	COG1652	LysM domain
D9C08_10900	COG4193	domain, Protein
D9C08_10910	COG3628	GPW Gp25 family protein
D9C08_10915	COG3299	homolog of phage Mu protein gp47
D9C08_10920	COG3778	Protein conserved in bacteria
D9C08_10960	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C08_10960	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_10980	COG0306	phosphate transporter
D9C08_10985	COG1392	Phosphate transport regulator
D9C08_10990	COG0531	amino acid
D9C08_10995	COG0346	lactoylglutathione lyase activity
D9C08_11000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C08_11005	COG0463	Glycosyl transferase, family 2
D9C08_11010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C08_11015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C08_11020	COG2362	D-Aminopeptidase
D9C08_11025	COG0601	transmembrane transport
D9C08_11030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C08_11035	COG0444	Belongs to the ABC transporter superfamily
D9C08_11040	COG4166	transmembrane transport
D9C08_11045	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C08_11050	COG4948	Mandelate Racemase Muconate Lactonizing
D9C08_11055	COG0791	NLP P60 protein
D9C08_11060	COG4608	Belongs to the ABC transporter superfamily
D9C08_11065	COG2706	6-phosphogluconolactonase activity
D9C08_11075	COG1607	acyl-coa hydrolase
D9C08_11080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9C08_11080	COG1017	nitric oxide dioxygenase activity
D9C08_11090	COG2323	membrane
D9C08_11095	COG2318	DinB family
D9C08_11100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_11105	COG2076	Multidrug Resistance protein
D9C08_11110	COG2076	Multidrug Resistance protein
D9C08_11115	COG0788	formyltetrahydrofolate deformylase activity
D9C08_11120	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C08_11125	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9C08_11130	COG1764	response to oxidative stress
D9C08_11135	COG1846	Transcriptional regulator
D9C08_11140	COG1764	response to oxidative stress
D9C08_11150	COG0590	tRNA wobble adenosine to inosine editing
D9C08_11155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C08_11160	COG1404	Belongs to the peptidase S8 family
D9C08_11165	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_11170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C08_11175	COG1122	ATPase activity
D9C08_11180	COG4721	ABC-type cobalt transport system, permease component
D9C08_11190	COG0745	RESPONSE REGULATOR receiver
D9C08_11195	COG5002	protein histidine kinase activity
D9C08_11195	COG3850	Histidine kinase
D9C08_11200	COG3212	peptidase
D9C08_11205	COG3212	peptidase
D9C08_11220	COG2239	Acts as a magnesium transporter
D9C08_11225	COG0789	Transcriptional regulator
D9C08_11240	COG1846	Transcriptional regulator
D9C08_11245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C08_11250	COG0726	polysaccharide deacetylase
D9C08_11255	COG1408	metallophosphoesterase
D9C08_11265	COG0463	Glycosyl transferase, family 2
D9C08_11270	COG1793	dna ligase
D9C08_11270	COG3285	dna ligase
D9C08_11275	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9C08_11280	COG5001	Diguanylate cyclase
D9C08_11280	COG3300	MHYT domain
D9C08_11285	COG0586	Pfam SNARE associated Golgi protein
D9C08_11290	COG0861	Integral membrane protein TerC family
D9C08_11295	COG1191	sigma factor activity
D9C08_11315	COG0501	Belongs to the peptidase M48B family
D9C08_11320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C08_11335	COG3594	Acyltransferase
D9C08_11340	COG5002	protein histidine kinase activity
D9C08_11345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C08_11355	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9C08_11360	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9C08_11365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C08_11370	COG0436	Aminotransferase
D9C08_11375	COG1850	ribulose-bisphosphate carboxylase activity
D9C08_11380	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9C08_11385	COG0235	Class ii aldolase
D9C08_11390	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9C08_11395	COG3339	Conserved Protein
D9C08_11410	COG3852	Histidine kinase
D9C08_11415	COG1846	Transcriptional regulator
D9C08_11420	COG1360	Flagellar Motor Protein
D9C08_11425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C08_11430	COG0542	response to heat
D9C08_11435	COG3949	Membrane
D9C08_11440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9C08_11445	COG0720	synthase
D9C08_11450	COG0602	queuosine metabolic process
D9C08_11455	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9C08_11465	COG4873	Protein conserved in bacteria
D9C08_11475	COG3773	Cell wall hydrolase
D9C08_11480	COG2244	polysaccharide biosynthetic process
D9C08_11485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_11490	COG2217	Heavy metal translocating P-type atpase
D9C08_11500	COG0006	proline dipeptidase activity
D9C08_11505	COG1609	Transcriptional regulator
D9C08_11515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_11515	COG2190	(PTS) system
D9C08_11515	COG1263	PTS System
D9C08_11520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_11525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9C08_11535	COG1533	DNA photolyase activity
D9C08_11540	COG0456	acetyltransferase
D9C08_11545	COG0840	transmembrane signaling receptor activity
D9C08_11550	COG2084	Dehydrogenase
D9C08_11565	COG3328	transposase activity
D9C08_11575	COG2340	Cysteine-rich secretory protein family
D9C08_11580	COG0768	penicillin binding
D9C08_11585	COG4191	Histidine kinase
D9C08_11590	COG0436	Aminotransferase
D9C08_11600	COG0784	Response regulator, receiver
D9C08_11600	COG0835	chemotaxis
D9C08_11610	COG2814	Major facilitator Superfamily
D9C08_11615	COG1376	ErfK ybiS ycfS ynhG family protein
D9C08_11620	COG1408	metallophosphoesterase
D9C08_11625	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_11630	COG2200	EAL domain
D9C08_11635	COG4703	Protein of unknown function (DUF1797)
D9C08_11640	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9C08_11650	COG0517	IMP dehydrogenase activity
D9C08_11655	COG0583	DNA-binding transcription factor activity
D9C08_11660	COG0716	FMN binding
D9C08_11670	COG0716	FMN binding
D9C08_11675	COG2171	N-acyltransferase activity
D9C08_11680	COG1473	amidohydrolase
D9C08_11690	COG0668	transmembrane transport
D9C08_11695	COG0450	alkyl hydroperoxide reductase
D9C08_11700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_11720	COG0746	molybdenum cofactor guanylyltransferase activity
D9C08_11725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C08_11730	COG0303	'Molybdopterin
D9C08_11735	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9C08_11740	COG0314	molybdopterin synthase activity
D9C08_11745	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9C08_11750	COG1132	(ABC) transporter
D9C08_11755	COG1132	(ABC) transporter
D9C08_11765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C08_11770	COG1136	(ABC) transporter
D9C08_11775	COG0577	efflux transmembrane transporter activity
D9C08_11780	COG1349	DNA-binding transcription factor activity
D9C08_11785	COG1105	Belongs to the carbohydrate kinase PfkB family
D9C08_11790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_11790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C08_11790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C08_11795	COG0681	Belongs to the peptidase S26 family
D9C08_11805	COG0488	(ABC) transporter
D9C08_11810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C08_11820	COG2309	aminopeptidase activity
D9C08_11830	COG1077	Cell shape determining protein MreB Mrl
D9C08_11835	COG2002	toxin-antitoxin pair type II binding
D9C08_11840	COG3852	Histidine kinase
D9C08_11855	COG2105	PFAM AIG2 family protein
D9C08_11855	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9C08_11860	COG0569	domain protein
D9C08_11865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C08_11870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C08_11880	COG0561	phosphatase activity
D9C08_11885	COG0242	peptide deformylase activity
D9C08_11895	COG0497	DNA recombination
D9C08_11900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C08_11905	COG0022	dehydrogenase e1 component
D9C08_11910	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C08_11915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C08_11920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_11935	COG1982	Orn Lys Arg decarboxylase major
D9C08_11940	COG4476	Belongs to the UPF0223 family
D9C08_11945	COG4493	Belongs to the UPF0637 family
D9C08_11955	COG0483	inositol monophosphate 1-phosphatase activity
D9C08_11965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9C08_12020	COG4896	Protein conserved in bacteria
D9C08_12030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9C08_12035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C08_12040	COG2066	Belongs to the glutaminase family
D9C08_12045	COG4838	Belongs to the UPF0358 family
D9C08_12050	COG0772	Belongs to the SEDS family
D9C08_12055	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9C08_12065	COG1612	heme a metabolic process
D9C08_12070	COG0109	protoheme IX farnesyltransferase activity
D9C08_12075	COG2010	Cytochrome c
D9C08_12075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C08_12080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C08_12085	COG1845	cytochrome c oxidase, subunit III
D9C08_12090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C08_12095	COG3336	cytochrome c oxidase
D9C08_12105	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9C08_12110	COG2340	Cysteine-rich secretory protein family
D9C08_12125	COG3679	Belongs to the UPF0342 family
D9C08_12130	COG4471	UPF0298 protein
D9C08_12135	COG0742	ribosomal rna small subunit methyltransferase
D9C08_12140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9C08_12145	COG3314	Sporulation integral membrane protein YlbJ
D9C08_12150	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C08_12155	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9C08_12160	COG1323	Belongs to the UPF0348 family
D9C08_12170	COG1399	metal-binding, possibly nucleic acid-binding protein
D9C08_12175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9C08_12185	COG0454	-acetyltransferase
D9C08_12190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C08_12195	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9C08_12200	COG2001	Belongs to the MraZ family
D9C08_12205	COG0275	rRNA processing
D9C08_12210	COG4839	cell division protein FtsL
D9C08_12220	COG0768	penicillin binding
D9C08_12225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9C08_12230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C08_12235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C08_12240	COG0772	Belongs to the SEDS family
D9C08_12245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C08_12250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9C08_12255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9C08_12260	COG3879	Bacterial protein of unknown function (DUF881)
D9C08_12265	COG3879	Bacterial protein of unknown function (DUF881)
D9C08_12270	COG3856	small basic protein
D9C08_12275	COG0849	cell division
D9C08_12280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9C08_12285	COG1404	Belongs to the peptidase S8 family
D9C08_12285	COG4412	M6 family metalloprotease domain protein
D9C08_12295	COG1191	sigma factor activity
D9C08_12300	COG1191	sigma factor activity
D9C08_12305	COG1119	ATPase activity
D9C08_12310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C08_12315	COG1873	PFAM PRC-barrel domain
D9C08_12325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9C08_12330	COG1799	cell septum assembly
D9C08_12335	COG0762	integral membrane protein
D9C08_12340	COG2302	S4 RNA-binding domain
D9C08_12345	COG3599	regulation of cell shape
D9C08_12350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9C08_12360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C08_12365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9C08_12370	COG0564	pseudouridine synthase activity
D9C08_12375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9C08_12380	COG2233	PERMEase
D9C08_12385	COG0540	Belongs to the ATCase OTCase family
D9C08_12390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C08_12395	COG0505	Belongs to the CarA family
D9C08_12400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C08_12405	COG0543	2 iron, 2 sulfur cluster binding
D9C08_12410	COG0167	dihydroorotate dehydrogenase activity
D9C08_12415	COG0284	orotidine-5'-phosphate decarboxylase activity
D9C08_12420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9C08_12425	COG0175	sulfate reduction
D9C08_12430	COG0306	phosphate transporter
D9C08_12435	COG2046	Belongs to the sulfate adenylyltransferase family
D9C08_12440	COG0529	Catalyzes the synthesis of activated sulfate
D9C08_12450	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9C08_12455	COG1648	precorrin-2 dehydrogenase activity
D9C08_12465	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C08_12470	COG1561	YicC-like family, N-terminal region
D9C08_12475	COG2052	Domain of unknown function (DUF370)
D9C08_12480	COG0194	GDP metabolic process
D9C08_12485	COG1758	RNA polymerase activity
D9C08_12490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C08_12495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C08_12500	COG0242	peptide deformylase activity
D9C08_12505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9C08_12510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C08_12510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9C08_12515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9C08_12520	COG0631	protein serine/threonine phosphatase activity
D9C08_12525	COG0515	serine threonine protein kinase
D9C08_12525	COG2815	serine threonine protein kinase
D9C08_12530	COG1162	GTPase activity
D9C08_12535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9C08_12540	COG1564	THIamine pyrophosphokinase
D9C08_12550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9C08_12555	COG1302	Protein conserved in bacteria
D9C08_12560	COG1461	Dihydroxyacetone kinase
D9C08_12565	COG1760	l-serine dehydratase
D9C08_12570	COG1760	l-serine dehydratase
D9C08_12575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9C08_12580	COG1349	DNA-binding transcription factor activity
D9C08_12580	COG2050	protein possibly involved in aromatic compounds catabolism
D9C08_12585	COG0416	fatty acid biosynthetic process
D9C08_12590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C08_12595	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_12600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C08_12605	COG0571	ribonuclease III activity
D9C08_12610	COG1196	nuclear chromosome segregation
D9C08_12615	COG0552	protein localization to endoplasmic reticulum
D9C08_12625	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9C08_12630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9C08_12635	COG0228	four-way junction DNA binding
D9C08_12640	COG1837	Belongs to the UPF0109 family
D9C08_12650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9C08_12655	COG0336	Belongs to the RNA methyltransferase TrmD family
D9C08_12660	COG0335	large ribosomal subunit rRNA binding
D9C08_12665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C08_12670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C08_12680	COG2257	FlhB HrpN YscU SpaS Family
D9C08_12685	COG0045	succinate-CoA ligase (ADP-forming) activity
D9C08_12690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9C08_12695	COG0758	DNA mediated transformation
D9C08_12700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C08_12705	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9C08_12710	COG4974	Belongs to the 'phage' integrase family
D9C08_12715	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9C08_12720	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9C08_12725	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C08_12730	COG1815	bacterial-type flagellum-dependent cell motility
D9C08_12735	COG1558	bacterial-type flagellum-dependent cell motility
D9C08_12740	COG1677	Flagellar hook-basal body complex protein FliE
D9C08_12745	COG1766	The M ring may be actively involved in energy transduction
D9C08_12750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C08_12755	COG1317	bacterial-type flagellum organization
D9C08_12760	COG1157	protein secretion by the type III secretion system
D9C08_12765	COG2882	bacterial-type flagellum organization
D9C08_12770	COG3334	PFAM MgtE intracellular
D9C08_12775	COG3144	bacterial-type flagellum assembly
D9C08_12780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9C08_12785	COG4786	Flagellar basal body rod
D9C08_12790	COG1582	Flagellar protein (FlbD)
D9C08_12795	COG1580	Controls the rotational direction of flagella during chemotaxis
D9C08_12800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C08_12805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C08_12805	COG1776	CheC inhibitor of MCP methylation
D9C08_12810	COG2201	protein-glutamate methylesterase activity
D9C08_12815	COG3190	flagellar
D9C08_12820	COG1338	Plays a role in the flagellum-specific transport system
D9C08_12825	COG1987	bacterial-type flagellum assembly
D9C08_12830	COG1684	flagellar biosynthetic protein fliR
D9C08_12835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C08_12840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C08_12845	COG1419	protein localization to endoplasmic reticulum
D9C08_12850	COG0455	bacterial-type flagellum organization
D9C08_12855	COG2201	protein-glutamate methylesterase activity
D9C08_12860	COG0643	Histidine kinase
D9C08_12860	COG2198	Histidine kinase
D9C08_12865	COG0835	chemotaxis
D9C08_12870	COG1776	CheC inhibitor of MCP methylation
D9C08_12875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9C08_12880	COG1191	sigma factor activity
D9C08_12890	COG0052	Belongs to the universal ribosomal protein uS2 family
D9C08_12895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9C08_12900	COG0528	UMP kinase activity
D9C08_12905	COG0233	cytoplasmic translational termination
D9C08_12910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9C08_12915	COG4589	Belongs to the CDS family
D9C08_12920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9C08_12925	COG0750	zinc metalloprotease
D9C08_12930	COG0442	prolyl-tRNA aminoacylation
D9C08_12935	COG2176	DNA-directed DNA polymerase activity
D9C08_12940	COG0779	Required for maturation of 30S ribosomal subunits
D9C08_12945	COG0195	Participates in both transcription termination and antitermination
D9C08_12950	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9C08_12955	COG1358	cellular component organization or biogenesis
D9C08_12960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9C08_12965	COG1550	Protein conserved in bacteria
D9C08_12970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9C08_12975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9C08_12980	COG0196	riboflavin kinase activity
D9C08_12985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9C08_12990	COG1185	polyribonucleotide nucleotidyltransferase activity
D9C08_12995	COG0726	polysaccharide deacetylase
D9C08_13000	COG0612	Peptidase, M16
D9C08_13005	COG1873	PFAM PRC-barrel domain
D9C08_13010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C08_13015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C08_13020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9C08_13025	COG0527	aspartate kinase activity
D9C08_13030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C08_13035	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C08_13040	COG0740	serine-type endopeptidase activity
D9C08_13050	COG1674	ftsk spoiiie
D9C08_13050	COG4980	gas vesicle protein
D9C08_13055	COG2188	Transcriptional regulator
D9C08_13060	COG2814	Major facilitator Superfamily
D9C08_13065	COG0612	Peptidase, M16
D9C08_13070	COG0612	Peptidase, M16
D9C08_13075	COG0300	oxidoreductase activity
D9C08_13090	COG1426	Protein conserved in bacteria
D9C08_13095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9C08_13100	COG1546	Belongs to the CinA family
D9C08_13100	COG1058	Belongs to the CinA family
D9C08_13105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9C08_13110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C08_13115	COG1418	mRNA catabolic process
D9C08_13120	COG1692	metallophosphoesterase
D9C08_13125	COG2359	stage V sporulation protein S
D9C08_13130	COG1063	alcohol dehydrogenase
D9C08_13135	COG0156	8-amino-7-oxononanoate synthase activity
D9C08_13145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C08_13150	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9C08_13160	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9C08_13165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9C08_13240	COG3328	transposase activity
D9C08_13260	COG3226	Transcriptional regulator
D9C08_13270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C08_13275	COG1404	Belongs to the peptidase S8 family
D9C08_13285	COG4195	phage-related replication protein
D9C08_13290	COG1764	response to oxidative stress
D9C08_13295	COG2076	Multidrug Resistance protein
D9C08_13300	COG2076	Multidrug Resistance protein
D9C08_13315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9C08_13320	COG1923	regulation of RNA biosynthetic process
D9C08_13335	COG1780	Probably involved in ribonucleotide reductase function
D9C08_13340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C08_13345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C08_13350	COG4112	unkown
D9C08_13355	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C08_13365	COG0464	growth
D9C08_13370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9C08_13375	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9C08_13380	COG0789	Transcriptional regulator
D9C08_13385	COG0174	glutamine synthetase
D9C08_13405	COG5444	nuclease activity
D9C08_13435	COG4282	regulation of fungal-type cell wall biogenesis
D9C08_13450	COG3328	transposase activity
D9C08_13460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_13475	COG3655	Transcriptional regulator
D9C08_13500	COG0135	phosphoribosylanthranilate isomerase activity
D9C08_13505	COG2211	Major facilitator Superfamily
D9C08_13510	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C08_13515	COG1940	carbohydrate kinase activity
D9C08_13520	COG2115	Belongs to the xylose isomerase family
D9C08_13525	COG1070	Carbohydrate kinase
D9C08_13540	COG3328	transposase activity
D9C08_13545	COG1525	nuclease
D9C08_13550	COG2814	Major facilitator Superfamily
D9C08_13555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C08_13570	COG0756	dUTP diphosphatase activity
D9C08_13615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C08_13625	COG3832	glyoxalase III activity
D9C08_13670	COG4195	phage-related replication protein
D9C08_13680	COG0346	lactoylglutathione lyase activity
D9C08_13690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9C08_13695	COG1388	LysM domain
D9C08_13700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C08_13705	COG4224	UPF0291 protein
D9C08_13710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9C08_13720	COG3763	UPF0154 protein
D9C08_13730	COG0785	Cytochrome C biogenesis protein
D9C08_13735	COG2201	protein-glutamate methylesterase activity
D9C08_13740	COG4846	Membrane protein involved in cytochrome C biogenesis
D9C08_13755	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C08_13770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9C08_13775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_13795	COG0824	Thioesterase
D9C08_13805	COG4841	protein insertion into membrane
D9C08_13810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9C08_13815	COG1832	CoA-binding protein
D9C08_13820	COG0187	DNA topoisomerase II activity
D9C08_13825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C08_13835	COG1115	amino acid carrier protein
D9C08_13840	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9C08_13860	COG2246	polysaccharide biosynthetic process
D9C08_13865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C08_13870	COG0586	Pfam SNARE associated Golgi protein
D9C08_13875	COG2404	hydrolase activity, acting on ester bonds
D9C08_13880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C08_13885	COG1024	Enoyl-CoA hydratase
D9C08_13890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C08_13895	COG0511	ligase activity, forming carbon-carbon bonds
D9C08_13900	COG0439	Biotin carboxylase
D9C08_13905	COG0318	PFAM AMP-dependent synthetase and ligase
D9C08_13910	COG1960	acyl-CoA dehydrogenase activity
D9C08_13930	COG1649	PFAM Uncharacterised BCR, COG1649
D9C08_13945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C08_13950	COG2027	D-alanyl-D-alanine carboxypeptidase
D9C08_13955	COG2017	converts alpha-aldose to the beta-anomer
D9C08_13960	COG0534	Mate efflux family protein
D9C08_13975	COG0582	viral genome integration into host DNA
D9C08_13980	COG0166	Belongs to the GPI family
D9C08_13985	COG0405	Gamma-glutamyltransferase
D9C08_13990	COG0583	DNA-binding transcription factor activity
D9C08_13995	COG0604	alcohol dehydrogenase
D9C08_14000	COG0493	'glutamate synthase
D9C08_14005	COG0067	glutamate synthase
D9C08_14005	COG0069	glutamate synthase activity
D9C08_14005	COG0070	glutamate synthase
D9C08_14010	COG0583	DNA-binding transcription factor activity
D9C08_14040	COG0300	oxidoreductase activity
D9C08_14045	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C08_14055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_14070	COG1131	(ABC) transporter
D9C08_14080	COG2814	Major facilitator Superfamily
D9C08_14090	COG2323	membrane
D9C08_14095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C08_14105	COG2323	membrane
D9C08_14120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C08_14140	COG3546	catalase activity
D9C08_14155	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C08_14180	COG0840	transmembrane signaling receptor activity
D9C08_14180	COG5278	phosphoserine phosphatase activity
D9C08_14185	COG2368	4-hydroxyphenylacetate
D9C08_14190	COG4305	rare lipoprotein A
D9C08_14195	COG3619	membrane
D9C08_14215	COG2140	Oxalate decarboxylase
D9C08_14245	COG2720	vancomycin resistance protein
D9C08_14255	COG3655	Transcriptional regulator
D9C08_14260	COG3739	integral membrane protein
D9C08_14265	COG0583	DNA-binding transcription factor activity
D9C08_14270	COG0697	spore germination
D9C08_14280	COG0693	protein deglycase activity
D9C08_14285	COG2367	Beta-lactamase
D9C08_14315	COG0574	Belongs to the PEP-utilizing enzyme family
D9C08_14315	COG3848	Pyruvate phosphate dikinase
D9C08_14320	COG0726	polysaccharide deacetylase
D9C08_14330	COG2314	TM2 domain
D9C08_14335	COG1396	sequence-specific DNA binding
D9C08_14415	COG3655	Transcriptional regulator
D9C08_14445	COG3328	transposase activity
D9C08_14465	COG0457	Tetratricopeptide repeat
D9C08_14470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_14480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C08_14485	COG2226	methyltransferase
D9C08_14490	COG2211	Major facilitator Superfamily
D9C08_14495	COG3328	transposase activity
D9C08_14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C08_14545	COG5444	nuclease activity
D9C08_14550	COG4282	regulation of fungal-type cell wall biogenesis
D9C08_14555	COG1231	oxidoreductase activity
D9C08_14560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C08_14565	COG0662	Cupin 2, conserved barrel domain protein
D9C08_14565	COG2207	Transcriptional regulator
D9C08_14570	COG0456	acetyltransferase
D9C08_14575	COG1309	transcriptional regulator
D9C08_14580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C08_14585	COG3708	Transcriptional regulator
D9C08_14590	COG2378	regulation of single-species biofilm formation
D9C08_14600	COG0640	Transcriptional regulator
D9C08_14605	COG0741	lytic transglycosylase activity
D9C08_14620	COG2322	membrane
D9C08_14635	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C08_14640	COG3239	Fatty acid desaturase
D9C08_14645	COG4585	Histidine kinase
D9C08_14650	COG2197	response regulator
D9C08_14655	COG1388	LysM domain
D9C08_14655	COG3584	3D domain protein
D9C08_14660	COG0514	ATP-dependent DNA helicase (RecQ)
D9C08_14675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C08_14680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C08_14695	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C08_14720	COG1012	belongs to the aldehyde dehydrogenase family
D9C08_14725	COG1657	PFAM Prenyltransferase squalene oxidase
D9C08_14730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C08_14735	COG0733	neurotransmitter:sodium symporter activity
D9C08_14740	COG0385	Bile acid
D9C08_14745	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C08_14750	COG0567	Dehydrogenase, E1 component
D9C08_14755	COG4548	von Willebrand factor, type A
D9C08_14760	COG0714	Associated with various cellular activities
D9C08_14765	COG2032	superoxide dismutase activity
D9C08_14770	COG0791	NLP P60 protein
D9C08_14770	COG1388	LysM domain
D9C08_14775	COG1819	glycosyl
D9C08_14780	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C08_14785	COG0534	Mate efflux family protein
D9C08_14790	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_14800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C08_14805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C08_14815	COG2962	Rard protein
D9C08_14830	COG2610	gluconate transmembrane transporter activity
D9C08_14835	COG1942	4-Oxalocrotonate Tautomerase
D9C08_14840	COG1733	regulation of RNA biosynthetic process
D9C08_14845	COG0778	Nitroreductase
D9C08_14850	COG0400	carboxylic ester hydrolase activity
D9C08_14855	COG0346	lactoylglutathione lyase activity
D9C08_14865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C08_14870	COG0793	Belongs to the peptidase S41A family
D9C08_14870	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_14875	COG2226	methyltransferase
D9C08_14885	COG1876	peptidase activity
D9C08_14890	COG0813	purine-nucleoside phosphorylase activity
D9C08_14905	COG0671	phosphoesterase, PA-phosphatase related
D9C08_14930	COG4479	Belongs to the UPF0346 family
D9C08_14940	COG1509	lysine 2,3-aminomutase activity
D9C08_14945	COG0456	acetyltransferase
D9C08_14950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C08_14960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C08_14965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C08_14980	COG0456	acetyltransferase
D9C08_14985	COG0463	Glycosyl transferase, family 2
D9C08_15000	COG4641	Protein conserved in bacteria
D9C08_15005	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D9C08_15010	COG1086	Polysaccharide biosynthesis protein
D9C08_15015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C08_15020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C08_15025	COG1846	Transcriptional regulator
D9C08_15030	COG0534	Mate efflux family protein
D9C08_15040	COG4698	Protein conserved in bacteria
D9C08_15045	COG2755	lipolytic protein G-D-S-L family
D9C08_15050	COG1999	signal sequence binding
D9C08_15060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9C08_15065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C08_15070	COG1272	protein, Hemolysin III
D9C08_15075	COG0204	Acyl-transferase
D9C08_15080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C08_15085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C08_15095	COG2521	methyltransferase
D9C08_15095	COG2136	Putative SAM-dependent methyltransferase
D9C08_15105	COG0129	dihydroxy-acid dehydratase activity
D9C08_15110	COG1413	lyase activity
D9C08_15115	COG1418	mRNA catabolic process
D9C08_15120	COG0386	Belongs to the glutathione peroxidase family
D9C08_15125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9C08_15130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C08_15140	COG1278	Cold shock
D9C08_15160	COG0328	RNA-DNA hybrid ribonuclease activity
D9C08_15165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9C08_15170	COG0328	RNA-DNA hybrid ribonuclease activity
D9C08_15180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C08_15195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C08_15205	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9C08_15215	COG2233	PERMEase
D9C08_15220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C08_15225	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9C08_15235	COG0800	Aldolase
D9C08_15240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C08_15245	COG1609	Transcriptional regulator
D9C08_15250	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9C08_15255	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_15260	COG1199	ATP-dependent helicase activity
D9C08_15275	COG0116	Belongs to the methyltransferase superfamily
D9C08_15290	COG4474	Belongs to the UPF0398 family
D9C08_15305	COG3359	exonuclease
D9C08_15310	COG1205	dead DEAH box helicase
D9C08_15310	COG1111	helicase
D9C08_15315	COG2190	(PTS) system
D9C08_15320	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C08_15355	COG3331	DNA recombination
D9C08_15360	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C08_15360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C08_15370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9C08_15375	COG3935	DnaD domain protein
D9C08_15380	COG0017	Asparaginyl-tRNA synthetase
D9C08_15385	COG0436	Aminotransferase
D9C08_15390	COG5353	protein conserved in bacteria
D9C08_15400	COG1199	ATP-dependent helicase activity
D9C08_15400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9C08_15405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9C08_15410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9C08_15415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9C08_15420	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D9C08_15420	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D9C08_15425	COG0617	tRNA 3'-terminal CCA addition
D9C08_15430	COG0438	transferase activity, transferring glycosyl groups
D9C08_15435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C08_15440	COG1803	Methylglyoxal synthase
D9C08_15445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9C08_15450	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C08_15455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C08_15465	COG4347	Protein of unknown function (DUF1405)
D9C08_15470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C08_15470	COG2010	Cytochrome c
D9C08_15475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C08_15480	COG0723	plastoquinol--plastocyanin reductase activity
D9C08_15490	COG5582	Belongs to the UPF0302 family
D9C08_15495	COG0457	Tetratricopeptide repeat
D9C08_15500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9C08_15505	COG0287	Prephenate dehydrogenase
D9C08_15520	COG0133	tryptophan synthase activity
D9C08_15525	COG0135	phosphoribosylanthranilate isomerase activity
D9C08_15535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9C08_15540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C08_15545	COG4401	Chorismate mutase type I
D9C08_15550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9C08_15555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9C08_15560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9C08_15565	COG0105	UTP biosynthetic process
D9C08_15570	COG0142	geranyltranstransferase activity
D9C08_15575	COG2226	methyltransferase
D9C08_15580	COG0142	geranyltranstransferase activity
D9C08_15590	COG0302	gtp cyclohydrolase
D9C08_15605	COG0776	regulation of translation
D9C08_15610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C08_15625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9C08_15630	COG1160	GTP binding
D9C08_15660	COG1304	FMN binding
D9C08_15665	COG0539	negative regulation of cytoplasmic translation
D9C08_15670	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9C08_15680	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9C08_15685	COG2959	enzyme of heme biosynthesis
D9C08_15690	COG3773	Cell wall hydrolase
D9C08_15690	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_15695	COG2339	peptidase activity
D9C08_15700	COG0492	ferredoxin-NADP+ reductase activity
D9C08_15705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C08_15710	COG4862	establishment of competence for transformation
D9C08_15715	COG1408	metallophosphoesterase
D9C08_15725	COG1388	LysM domain
D9C08_15730	COG1266	CAAX protease self-immunity
D9C08_15735	COG0514	ATP-dependent DNA helicase (RecQ)
D9C08_15740	COG4955	Helix-turn-helix domain
D9C08_15745	COG1141	Ferredoxin
D9C08_15750	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9C08_15755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C08_15760	COG0710	3-dehydroquinate dehydratase activity
D9C08_15770	COG1595	DNA-templated transcription, initiation
D9C08_15775	COG5002	protein histidine kinase activity
D9C08_15780	COG0745	RESPONSE REGULATOR receiver
D9C08_15785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C08_15790	COG1333	cytochrome c biogenesis protein
D9C08_15795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_15800	COG1187	pseudouridine synthase activity
D9C08_15805	COG0700	Nucleoside recognition
D9C08_15810	COG2715	membrane protein required for spore maturation
D9C08_15815	COG1686	Belongs to the peptidase S11 family
D9C08_15825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9C08_15830	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9C08_15835	COG1547	Domain of unknown function (DUF309)
D9C08_15840	COG0456	acetyltransferase
D9C08_15845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9C08_15850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C08_15850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C08_15855	COG0307	riboflavin synthase, alpha
D9C08_15860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C08_15860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C08_15870	COG0681	Belongs to the peptidase S26 family
D9C08_15880	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9C08_15930	COG3328	transposase activity
D9C08_15940	COG3012	SEC-C Motif Domain Protein
D9C08_15950	COG0457	Tetratricopeptide repeat
D9C08_15960	COG3328	transposase activity
D9C08_16020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9C08_16035	COG4086	secreted protein
D9C08_16040	COG0019	diaminopimelate decarboxylase activity
D9C08_16045	COG0697	spore germination
D9C08_16060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C08_16080	COG1191	sigma factor activity
D9C08_16085	COG2172	sigma factor antagonist activity
D9C08_16090	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_16095	COG1686	Belongs to the peptidase S11 family
D9C08_16100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9C08_16105	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9C08_16110	COG4974	Belongs to the 'phage' integrase family
D9C08_16120	COG0735	belongs to the Fur family
D9C08_16125	COG1300	Membrane
D9C08_16135	COG0281	malic enzyme
D9C08_16140	COG1757	Na H antiporter
D9C08_16145	COG1027	Aspartate ammonia-lyase
D9C08_16150	COG0252	asparaginase activity
D9C08_16155	COG1396	sequence-specific DNA binding
D9C08_16160	COG1379	DNA repair
D9C08_16165	COG0494	nUDIX hydrolase
D9C08_16175	COG0667	Aldo Keto reductase
D9C08_16185	COG1073	alpha beta
D9C08_16195	COG4918	Iron-sulphur cluster biosynthesis
D9C08_16200	COG0456	acetyltransferase
D9C08_16200	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9C08_16205	COG2329	Antibiotic biosynthesis monooxygenase
D9C08_16210	COG0456	acetyltransferase
D9C08_16220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C08_16230	COG2211	Major facilitator Superfamily
D9C08_16235	COG0346	lactoylglutathione lyase activity
D9C08_16240	COG1072	(Pantothenic acid kinase))
D9C08_16245	COG3048	D-serine ammonia-lyase activity
D9C08_16250	COG0300	oxidoreductase activity
D9C08_16255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C08_16260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C08_16275	COG4187	Peptidase family M20/M25/M40
D9C08_16280	COG1902	pentaerythritol trinitrate reductase activity
D9C08_16285	COG0596	Alpha beta hydrolase
D9C08_16295	COG1234	tRNA 3'-trailer cleavage
D9C08_16300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9C08_16305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C08_16310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C08_16320	COG0706	membrane insertase activity
D9C08_16325	COG3361	conserved protein (COG2071)
D9C08_16330	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C08_16335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C08_16340	COG0346	lactoylglutathione lyase activity
D9C08_16345	COG1376	ErfK ybiS ycfS ynhG family protein
D9C08_16350	COG4129	membrane
D9C08_16355	COG1126	abc transporter atp-binding protein
D9C08_16360	COG0765	amino acid transport
D9C08_16365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C08_16375	COG1597	lipid kinase activity
D9C08_16380	COG2814	Major facilitator Superfamily
D9C08_16385	COG4978	Transcriptional regulator
D9C08_16385	COG0789	Transcriptional regulator
D9C08_16390	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C08_16395	COG0022	dehydrogenase e1 component
D9C08_16400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C08_16405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C08_16410	COG3426	butyrate kinase activity
D9C08_16415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C08_16420	COG0280	phosphate acetyltransferase
D9C08_16425	COG3829	transcription factor binding
D9C08_16425	COG3290	protein histidine kinase activity
D9C08_16435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9C08_16440	COG2079	MmgE PrpD family protein
D9C08_16445	COG0372	Belongs to the citrate synthase family
D9C08_16450	COG1960	acyl-CoA dehydrogenase activity
D9C08_16455	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C08_16460	COG0183	Belongs to the thiolase family
D9C08_16465	COG0584	glycerophosphoryl diester phosphodiesterase
D9C08_16470	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C08_16485	COG1902	pentaerythritol trinitrate reductase activity
D9C08_16490	COG0745	RESPONSE REGULATOR receiver
D9C08_16500	COG0750	zinc metalloprotease
D9C08_16505	COG0497	DNA recombination
D9C08_16510	COG1438	arginine binding
D9C08_16515	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9C08_16520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9C08_16525	COG0142	geranyltranstransferase activity
D9C08_16530	COG1722	exodeoxyribonuclease VII activity
D9C08_16535	COG1570	exodeoxyribonuclease VII activity
D9C08_16540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9C08_16545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C08_16550	COG1302	Protein conserved in bacteria
D9C08_16555	COG0439	Biotin carboxylase
D9C08_16560	COG0511	ligase activity, forming carbon-carbon bonds
D9C08_16610	COG3854	ATPases associated with a variety of cellular activities
D9C08_16620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9C08_16625	COG0006	proline dipeptidase activity
D9C08_16630	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9C08_16640	COG3872	metal-dependent enzyme
D9C08_16650	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C08_16655	COG1321	iron dependent repressor
D9C08_16660	COG0095	Lipoate-protein ligase
D9C08_16665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C08_16670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C08_16675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C08_16680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9C08_16685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C08_16700	COG1396	sequence-specific DNA binding
D9C08_16710	COG0681	Belongs to the peptidase S26 family
D9C08_16735	COG4940	Competence protein ComGF
D9C08_16745	COG4970	Tfp pilus assembly protein FimT
D9C08_16750	COG4537	Required for transformation and DNA binding
D9C08_16755	COG1459	type II secretion system
D9C08_16760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9C08_16765	COG0517	IMP dehydrogenase activity
D9C08_16770	COG0598	Magnesium transport protein CorA
D9C08_16775	COG1253	flavin adenine dinucleotide binding
D9C08_16780	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_16790	COG1393	Belongs to the ArsC family
D9C08_16805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C08_16815	COG0011	TIGRFAM Protein of
D9C08_16825	COG2866	Carboxypeptidase
D9C08_16830	COG1368	sulfuric ester hydrolase activity
D9C08_16835	COG1940	carbohydrate kinase activity
D9C08_16840	COG4483	Protein conserved in bacteria
D9C08_16845	COG0705	Rhomboid family
D9C08_16845	COG0457	Tetratricopeptide repeat
D9C08_16855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9C08_16860	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C08_16865	COG0438	transferase activity, transferring glycosyl groups
D9C08_16880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C08_16885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C08_16890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C08_16895	COG0581	inorganic phosphate transmembrane transporter activity
D9C08_16900	COG0573	inorganic phosphate transmembrane transporter activity
D9C08_16905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9C08_16915	COG0477	Major facilitator Superfamily
D9C08_16920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C08_16925	COG2839	Protein conserved in bacteria
D9C08_16930	COG5521	maltodextrose utilization protein MalA
D9C08_16935	COG1388	LysM domain
D9C08_16940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9C08_16945	COG4709	membrane
D9C08_16950	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9C08_16955	COG0735	belongs to the Fur family
D9C08_16960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C08_16970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9C08_16975	COG0513	Belongs to the DEAD box helicase family
D9C08_16985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9C08_16990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9C08_16995	COG2384	SAM-dependent methyltransferase
D9C08_17000	COG2010	Cytochrome c
D9C08_17010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9C08_17015	COG0358	DNA primase activity
D9C08_17020	COG1671	Belongs to the UPF0178 family
D9C08_17025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9C08_17030	COG0517	IMP dehydrogenase activity
D9C08_17035	COG0751	glycine-tRNA ligase activity
D9C08_17040	COG0752	glycyl-tRNA synthetase alpha subunit
D9C08_17045	COG1381	Involved in DNA repair and RecF pathway recombination
D9C08_17055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9C08_17060	COG0295	cytidine deaminase activity
D9C08_17065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9C08_17070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9C08_17075	COG1480	7TM receptor with intracellular HD hydrolase
D9C08_17080	COG1702	phosphate starvation-inducible protein PhoH
D9C08_17085	COG0561	phosphatase activity
D9C08_17100	COG4864	UPF0365 protein
D9C08_17105	COG1030	water channel activity
D9C08_17110	COG1610	YqeY-like protein
D9C08_17115	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9C08_17120	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9C08_17125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C08_17130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9C08_17135	COG2264	protein methyltransferase activity
D9C08_17140	COG0484	heat shock protein binding
D9C08_17145	COG0443	Heat shock 70 kDa protein
D9C08_17150	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9C08_17155	COG1420	regulation of RNA biosynthetic process
D9C08_17160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C08_17165	COG0481	GTPase activity
D9C08_17175	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C08_17180	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9C08_17185	COG0268	Binds directly to 16S ribosomal RNA
D9C08_17190	COG1466	dna polymerase III delta subunit
D9C08_17205	COG2333	competence protein COMEC
D9C08_17205	COG0658	competence protein
D9C08_17210	COG2131	deaminase
D9C08_17215	COG1596	polysaccharide export
D9C08_17215	COG1555	photosystem II stabilization
D9C08_17220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C08_17225	COG2226	methyltransferase
D9C08_17230	COG0799	negative regulation of ribosome biogenesis
D9C08_17235	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9C08_17240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9C08_17245	COG1534	Rna-binding protein
D9C08_17250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9C08_17255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C08_17260	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9C08_17270	COG2755	lipolytic protein G-D-S-L family
D9C08_17275	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_17275	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C08_17280	COG0398	Pfam SNARE associated Golgi protein
D9C08_17285	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D9C08_17295	COG3209	COG3209 Rhs family protein
D9C08_17315	COG0114	fumarate hydratase activity
D9C08_17320	COG0583	DNA-binding transcription factor activity
D9C08_17335	COG0457	Tetratricopeptide repeat
D9C08_17460	COG0789	Transcriptional regulator
D9C08_17460	COG4978	Transcriptional regulator
D9C08_17465	COG2814	Major facilitator Superfamily
D9C08_17470	COG0456	acetyltransferase
D9C08_17475	COG3328	transposase activity
D9C08_17485	COG1253	flavin adenine dinucleotide binding
D9C08_17495	COG0697	spore germination
D9C08_17500	COG0583	DNA-binding transcription factor activity
D9C08_17505	COG2072	flavoprotein involved in K transport
D9C08_17510	COG1230	cation diffusion facilitator family transporter
D9C08_17525	COG1114	Component of the transport system for branched-chain amino acids
D9C08_17530	COG1687	branched-chain amino acid
D9C08_17535	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D9C08_17540	COG1522	sequence-specific DNA binding
D9C08_17545	COG2732	(Barnase) inhibitor
D9C08_17555	COG1335	isochorismatase
D9C08_17570	COG2318	DinB family
D9C08_17580	COG2070	2-Nitropropane dioxygenase
D9C08_17595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C08_17615	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9C08_17620	COG1595	DNA-templated transcription, initiation
D9C08_17625	COG0667	Aldo Keto reductase
D9C08_17630	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_17635	COG5566	PFAM Mor transcription activator
D9C08_17640	COG0596	Alpha beta hydrolase
D9C08_17645	COG4991	sh3 domain protein
D9C08_17650	COG4991	sh3 domain protein
D9C08_17660	COG0346	lactoylglutathione lyase activity
D9C08_17670	COG5577	PFAM Coat F domain
D9C08_17675	COG1063	alcohol dehydrogenase
D9C08_17685	COG5577	PFAM Coat F domain
D9C08_17690	COG0789	Transcriptional regulator
D9C08_17700	COG1064	alcohol dehydrogenase
D9C08_17705	COG0693	protein deglycase activity
D9C08_17710	COG1621	beta-fructofuranosidase activity
D9C08_17715	COG3716	PTS system mannose fructose sorbose family IID component
D9C08_17720	COG3715	PTS system
D9C08_17725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C08_17730	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_17735	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D9C08_17735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C08_17745	COG1113	amino acid transport
D9C08_17750	COG1280	lysine exporter protein (LysE YggA)
D9C08_17755	COG1378	Sugar-specific transcriptional regulator TrmB
D9C08_17760	COG1595	DNA-templated transcription, initiation
D9C08_17780	COG2124	cytochrome p450
D9C08_17780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C08_17785	COG1309	transcriptional regulator
D9C08_17790	COG2226	methyltransferase
D9C08_17805	COG2116	formate transmembrane transporter activity
D9C08_17810	COG5609	conserved protein (DUF2294)
D9C08_17815	COG3383	formate dehydrogenase (NAD+) activity
D9C08_17820	COG2427	Protein of unknown function (DUF1641)
D9C08_17830	COG0626	cystathionine gamma-synthase activity
D9C08_17835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C08_17840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9C08_17845	COG2226	methyltransferase
D9C08_17860	COG0768	penicillin binding
D9C08_17865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9C08_17870	COG0572	uridine kinase
D9C08_17890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C08_17895	COG3906	Belongs to the UPF0473 family
D9C08_17900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9C08_17905	COG4472	Bacterial protein of unknown function (DUF965)
D9C08_17910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9C08_17915	COG0628	permease
D9C08_17920	COG1126	abc transporter atp-binding protein
D9C08_17925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C08_17935	COG0765	amino acid transport
D9C08_17955	COG3881	PFAM PRC-barrel domain
D9C08_17960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9C08_17965	COG0457	Tetratricopeptide repeat
D9C08_17970	COG0482	sulfurtransferase activity
D9C08_17975	COG1104	cysteine desulfurase activity
D9C08_17980	COG1959	2 iron, 2 sulfur cluster binding
D9C08_17985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9C08_17990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9C08_18000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9C08_18005	COG0124	histidyl-tRNA synthetase
D9C08_18015	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C08_18015	COG4991	sh3 domain protein
D9C08_18015	COG3103	Sh3 type 3 domain protein
D9C08_18020	COG1490	D-aminoacyl-tRNA deacylase activity
D9C08_18025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9C08_18030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C08_18035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9C08_18035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9C08_18040	COG5416	Lipopolysaccharide assembly protein A domain
D9C08_18045	COG0490	domain, Protein
D9C08_18050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C08_18050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C08_18060	COG2244	polysaccharide biosynthetic process
D9C08_18065	COG2323	membrane
D9C08_18075	COG1862	Preprotein translocase
D9C08_18080	COG0343	queuine tRNA-ribosyltransferase activity
D9C08_18085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9C08_18095	COG2255	four-way junction helicase activity
D9C08_18100	COG0632	four-way junction helicase activity
D9C08_18110	COG2814	Major facilitator Superfamily
D9C08_18115	COG0673	inositol 2-dehydrogenase activity
D9C08_18120	COG2112	serine threonine protein kinase
D9C08_18140	COG1115	amino acid carrier protein
D9C08_18145	COG0217	transcriptional regulatory protein
D9C08_18155	COG1388	LysM domain
D9C08_18160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9C08_18165	COG0157	Belongs to the NadC ModD family
D9C08_18170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9C08_18175	COG1104	cysteine desulfurase activity
D9C08_18180	COG1827	regulation of RNA biosynthetic process
D9C08_18185	COG0077	Prephenate dehydratase
D9C08_18190	COG4492	Belongs to the UPF0735 family
D9C08_18195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9C08_18200	COG3290	protein histidine kinase activity
D9C08_18210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9C08_18215	COG2868	ribosomal protein
D9C08_18220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9C08_18225	COG1994	Peptidase M50
D9C08_18230	COG0739	heme binding
D9C08_18235	COG2894	cell division
D9C08_18240	COG0850	regulation of cytokinetic process
D9C08_18245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9C08_18250	COG1792	Involved in formation and maintenance of cell shape
D9C08_18255	COG1077	Cell shape determining protein MreB Mrl
D9C08_18260	COG2003	Belongs to the UPF0758 family
D9C08_18265	COG0424	maF-like protein
D9C08_18275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9C08_18280	COG0285	dihydrofolate synthase activity
D9C08_18285	COG0525	valine-tRNA ligase activity
D9C08_18295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C08_18300	COG1388	LysM domain
D9C08_18305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C08_18310	COG0113	porphobilinogen synthase activity
D9C08_18315	COG1587	Uroporphyrinogen-III synthase
D9C08_18320	COG0181	hydroxymethylbilane synthase activity
D9C08_18325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C08_18330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9C08_18340	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9C08_18345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9C08_18350	COG0470	DNA polymerase III
D9C08_18350	COG1067	ATP-dependent peptidase activity
D9C08_18355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9C08_18360	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9C08_18365	COG1477	protein flavinylation
D9C08_18365	COG0457	Tetratricopeptide repeat
D9C08_18370	COG0066	3-isopropylmalate dehydratase activity
D9C08_18375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9C08_18380	COG0473	3-isopropylmalate dehydrogenase activity
D9C08_18385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C08_18390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9C08_18395	COG0440	acetolactate synthase activity
D9C08_18400	COG0028	Belongs to the TPP enzyme family
D9C08_18415	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D9C08_18445	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
D9C08_18470	COG0622	Phosphoesterase
D9C08_18475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9C08_18480	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9C08_18485	COG5401	PFAM Sporulation and spore germination
D9C08_18490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C08_18495	COG1846	Transcriptional regulator
D9C08_18500	COG2197	response regulator
D9C08_18505	COG0824	Thioesterase
D9C08_18510	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9C08_18515	COG1053	succinate dehydrogenase
D9C08_18520	COG2009	succinate dehydrogenase
D9C08_18525	COG1719	4-vinyl reductase, 4VR
D9C08_18530	COG0527	aspartate kinase activity
D9C08_18540	COG0322	excinuclease ABC activity
D9C08_18545	COG3118	belongs to the thioredoxin family
D9C08_18550	COG3534	alpha-L-arabinofuranosidase
D9C08_18555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9C08_18560	COG2086	electron transfer activity
D9C08_18565	COG1024	Enoyl-CoA hydratase
D9C08_18570	COG1309	transcriptional regulator
D9C08_18575	COG0318	PFAM AMP-dependent synthetase and ligase
D9C08_18580	COG3766	membrane
D9C08_18585	COG1193	negative regulation of DNA recombination
D9C08_18590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C08_18590	COG1796	DNA polymerase
D9C08_18595	COG1286	toxin biosynthetic process
D9C08_18600	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9C08_18605	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C08_18610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C08_18610	COG0072	phenylalanine-tRNA ligase activity
D9C08_18615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9C08_18625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C08_18635	COG3835	regulator
D9C08_18640	COG0277	FAD linked oxidase domain protein
D9C08_18645	COG0247	lactate metabolic process
D9C08_18650	COG0346	lactoylglutathione lyase activity
D9C08_18660	COG1966	Carbon starvation protein
D9C08_18665	COG3534	alpha-L-arabinofuranosidase
D9C08_18670	COG0395	ABC-type sugar transport system, permease component
D9C08_18675	COG1175	transmembrane transport
D9C08_18680	COG1653	transport
D9C08_18685	COG0371	Dehydrogenase
D9C08_18695	COG0235	Class ii aldolase
D9C08_18700	COG1069	ribulokinase activity
D9C08_18705	COG2160	L-arabinose isomerase activity
D9C08_18710	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C08_18715	COG1363	Peptidase, m42
D9C08_18725	COG3326	Membrane
D9C08_18730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9C08_18735	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9C08_18740	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9C08_18750	COG1346	cytolysis
D9C08_18755	COG1380	Effector of murein hydrolase LrgA
D9C08_18760	COG3279	Response regulator of the LytR AlgR family
D9C08_18765	COG3275	phosphorelay sensor kinase activity
D9C08_18775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C08_18785	COG0398	Pfam SNARE associated Golgi protein
D9C08_18790	COG1484	DNA-dependent DNA replication
D9C08_18795	COG3611	Membrane attachment protein
D9C08_18800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9C08_18805	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9C08_18810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C08_18815	COG1733	regulation of RNA biosynthetic process
D9C08_18820	COG2814	Major facilitator Superfamily
D9C08_18825	COG0656	L-ascorbic acid biosynthetic process
D9C08_18830	COG0237	dephospho-CoA kinase activity
D9C08_18835	COG1971	Probably functions as a manganese efflux pump
D9C08_18840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9C08_18845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C08_18845	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C08_18850	COG5002	protein histidine kinase activity
D9C08_18855	COG0745	RESPONSE REGULATOR receiver
D9C08_18860	COG0039	L-malate dehydrogenase activity
D9C08_18865	COG0538	isocitrate dehydrogenase activity
D9C08_18870	COG0372	Belongs to the citrate synthase family
D9C08_18880	COG2707	UPF0756 membrane protein
D9C08_18885	COG0628	permease
D9C08_18890	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9C08_18895	COG0469	pyruvate kinase activity
D9C08_18900	COG0205	6-phosphofructokinase activity
D9C08_18905	COG0825	malonyl-CoA metabolic process
D9C08_18910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9C08_18915	COG0281	malic enzyme
D9C08_18920	COG0587	DNA-directed DNA polymerase activity
D9C08_18940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9C08_18950	COG4109	DRTGG domain
D9C08_18955	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9C08_18960	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_18970	COG0165	Argininosuccinate lyase
D9C08_18975	COG0137	argininosuccinate synthase activity
D9C08_18980	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9C08_18985	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9C08_18995	COG0827	DNA restriction-modification system
D9C08_19000	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9C08_19005	COG3874	Sporulation protein YtfJ
D9C08_19015	COG1714	RDD family
D9C08_19020	COG0616	signal peptide processing
D9C08_19025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C08_19040	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9C08_19045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C08_19055	COG0301	tRNA thio-modification
D9C08_19060	COG1104	cysteine desulfurase activity
D9C08_19065	COG1114	Component of the transport system for branched-chain amino acids
D9C08_19070	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9C08_19075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C08_19080	COG1309	transcriptional regulator
D9C08_19085	COG1956	GAF domain-containing protein
D9C08_19090	COG2199	diguanylate cyclase activity
D9C08_19090	COG2203	Gaf domain
D9C08_19100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9C08_19105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C08_19110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C08_19115	COG0454	-acetyltransferase
D9C08_19120	COG0517	IMP dehydrogenase activity
D9C08_19125	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9C08_19130	COG1360	Flagellar Motor Protein
D9C08_19135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C08_19140	COG1609	Transcriptional regulator
D9C08_19145	COG1605	Chorismate mutase
D9C08_19145	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9C08_19150	COG3118	belongs to the thioredoxin family
D9C08_19155	COG4980	gas vesicle protein
D9C08_19160	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C08_19165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9C08_19170	COG1674	ftsk spoiiie
D9C08_19175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C08_19180	COG4848	Belongs to the UPF0354 family
D9C08_19185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_19200	COG1363	Peptidase, m42
D9C08_19205	COG5584	Small secreted protein
D9C08_19210	COG0281	malic enzyme
D9C08_19215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C08_19220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9C08_19230	COG0510	thiamine kinase activity
D9C08_19235	COG1523	belongs to the glycosyl hydrolase 13 family
D9C08_19240	COG1597	lipid kinase activity
D9C08_19250	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C08_19255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C08_19260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C08_19265	COG2252	PERMEase
D9C08_19270	COG4473	ABC transporter
D9C08_19275	COG1131	(ABC) transporter
D9C08_19280	COG1349	DNA-binding transcription factor activity
D9C08_19285	COG1187	pseudouridine synthase activity
D9C08_19290	COG2244	polysaccharide biosynthetic process
D9C08_19295	COG2081	HI0933 family
D9C08_19300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9C08_19320	COG1653	transport
D9C08_19325	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C08_19330	COG4209	transmembrane transport
D9C08_19340	COG1653	transport
D9C08_19345	COG0395	ABC-type sugar transport system, permease component
D9C08_19350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C08_19355	COG2124	cytochrome p450
D9C08_19360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9C08_19370	COG0156	8-amino-7-oxononanoate synthase activity
D9C08_19385	COG1073	alpha beta
D9C08_19410	COG1486	melibiose metabolic process
D9C08_19415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C08_19420	COG0495	leucyl-tRNA aminoacylation
D9C08_19430	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C08_19430	COG2202	Pas domain
D9C08_19435	COG2814	Major facilitator Superfamily
D9C08_19445	COG0577	efflux transmembrane transporter activity
D9C08_19450	COG1136	(ABC) transporter
D9C08_19455	COG2205	protein histidine kinase activity
D9C08_19460	COG0745	RESPONSE REGULATOR receiver
D9C08_19465	COG0577	efflux transmembrane transporter activity
D9C08_19470	COG1136	(ABC) transporter
D9C08_19485	COG1131	(ABC) transporter
D9C08_19490	COG1725	Transcriptional regulator
D9C08_19505	COG1242	4 iron, 4 sulfur cluster binding
D9C08_19510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9C08_19520	COG2267	carboxylic ester hydrolase activity
D9C08_19525	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9C08_19530	COG1113	amino acid transport
D9C08_19535	COG0367	asparagine synthase
D9C08_19540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9C08_19545	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9C08_19555	COG1506	peptidase
D9C08_19560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C08_19565	COG1116	anion transmembrane transporter activity
D9C08_19570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C08_19575	COG0494	nUDIX hydrolase
D9C08_19580	COG4824	toxin secretion phage lysis holin
D9C08_19585	COG0783	Belongs to the Dps family
D9C08_19600	COG1854	S-ribosylhomocysteine lyase activity
D9C08_19605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9C08_19610	COG0288	reversible hydration of carbon dioxide
D9C08_19615	COG0254	rRNA binding
D9C08_19620	COG1271	oxidase subunit
D9C08_19625	COG1294	oxidase, subunit
D9C08_19635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C08_19640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C08_19640	COG1321	iron dependent repressor
D9C08_19645	COG1121	(ABC) transporter
D9C08_19650	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C08_19660	COG4948	Mandelate Racemase Muconate Lactonizing
D9C08_19665	COG0318	PFAM AMP-dependent synthetase and ligase
D9C08_19670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9C08_19675	COG0596	Alpha beta hydrolase
D9C08_19680	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9C08_19685	COG1169	isochorismate synthase
D9C08_19690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C08_19695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C08_19700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C08_19705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C08_19710	COG0438	transferase activity, transferring glycosyl groups
D9C08_19720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C08_19725	COG0438	transferase activity, transferring glycosyl groups
D9C08_19730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C08_19735	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9C08_19740	COG0058	SHG alpha-glucan phosphorylase activity
D9C08_19745	COG0297	glycogen (starch) synthase activity
D9C08_19750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C08_19755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C08_19760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9C08_19885	COG3859	Proton-coupled thiamine transporter YuaJ
D9C08_19890	COG1247	-acetyltransferase
D9C08_19895	COG2268	Band 7 protein
D9C08_19900	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9C08_19905	COG2318	DinB family
D9C08_19920	COG1454	alcohol dehydrogenase
D9C08_19930	COG1510	regulation of RNA biosynthetic process
D9C08_19940	COG0569	domain protein
D9C08_19945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C08_19950	COG4682	membrane
D9C08_19955	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C08_19960	COG0477	Major facilitator Superfamily
D9C08_19965	COG5553	Cysteine dioxygenase type I
D9C08_19975	COG1968	undecaprenyl-diphosphatase activity
D9C08_19980	COG0628	permease
D9C08_19985	COG0673	inositol 2-dehydrogenase activity
D9C08_19990	COG4806	L-rhamnose isomerase
D9C08_19995	COG3254	rhamnose metabolic process
D9C08_20000	COG1070	Carbohydrate kinase
D9C08_20005	COG1349	DNA-binding transcription factor activity
D9C08_20010	COG3347	Dehydrogenase
D9C08_20010	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_20025	COG0840	transmembrane signaling receptor activity
D9C08_20030	COG0840	transmembrane signaling receptor activity
D9C08_20035	COG0840	transmembrane signaling receptor activity
D9C08_20060	COG1253	flavin adenine dinucleotide binding
D9C08_20065	COG2738	Putative neutral zinc metallopeptidase
D9C08_20080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9C08_20095	COG0166	Belongs to the GPI family
D9C08_20100	COG1979	alcohol dehydrogenase
D9C08_20105	COG1979	alcohol dehydrogenase
D9C08_20110	COG2155	Conserved Protein
D9C08_20115	COG1098	S1 RNA binding domain
D9C08_20120	COG0436	Aminotransferase
D9C08_20125	COG1522	sequence-specific DNA binding
D9C08_20130	COG2267	carboxylic ester hydrolase activity
D9C08_20140	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9C08_20145	COG2205	protein histidine kinase activity
D9C08_20155	COG5018	Exonuclease
D9C08_20165	COG2814	Major facilitator Superfamily
D9C08_20170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C08_20175	COG3011	Protein conserved in bacteria
D9C08_20185	COG3290	protein histidine kinase activity
D9C08_20190	COG4565	transcriptional regulatory protein
D9C08_20215	COG3493	citrate carrier protein
D9C08_20225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C08_20225	COG2111	Na H antiporter
D9C08_20230	COG2111	Na H antiporter
D9C08_20235	COG1006	Multisubunit Na H antiporter MnhC subunit
D9C08_20240	COG0651	ATP synthesis coupled electron transport
D9C08_20245	COG1863	multisubunit Na H antiporter MnhE subunit
D9C08_20250	COG2212	antiporter activity
D9C08_20255	COG1320	monovalent cation:proton antiporter activity
D9C08_20260	COG2050	protein possibly involved in aromatic compounds catabolism
D9C08_20265	COG2197	response regulator
D9C08_20270	COG4585	Histidine kinase
D9C08_20280	COG0142	geranyltranstransferase activity
D9C08_20300	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9C08_20305	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9C08_20310	COG1335	isochorismatase
D9C08_20315	COG5506	Protein of unknown function (DUF1694)
D9C08_20330	COG0628	permease
D9C08_20345	COG1418	mRNA catabolic process
D9C08_20350	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_20360	COG1511	domain protein
D9C08_20365	COG1674	ftsk spoiiie
D9C08_20365	COG0433	COG0433 Predicted ATPase
D9C08_20370	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C08_20375	COG5417	Belongs to the EsaB family
D9C08_20380	COG4842	Belongs to the WXG100 family
D9C08_20390	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C08_20390	COG2508	Transcriptional regulator
D9C08_20395	COG0686	Belongs to the AlaDH PNT family
D9C08_20400	COG5634	Uncharacterized conserved protein (DUF2278)
D9C08_20405	COG3251	PFAM MbtH domain protein
D9C08_20415	COG1535	isochorismatase
D9C08_20415	COG3433	isochorismatase activity
D9C08_20420	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9C08_20425	COG1169	isochorismate synthase
D9C08_20430	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_20435	COG2819	hydrolase of the alpha beta superfamily
D9C08_20440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C08_20445	COG1268	BioY protein
D9C08_20450	COG2056	Na+-H+ antiporter family
D9C08_20455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9C08_20460	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9C08_20465	COG3584	3D domain protein
D9C08_20480	COG1252	NADH dehydrogenase
D9C08_20485	COG0492	ferredoxin-NADP+ reductase activity
D9C08_20495	COG0516	GMP reductase activity
D9C08_20510	COG0316	Belongs to the HesB IscA family
D9C08_20515	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9C08_20520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C08_20530	COG4844	belongs to the
D9C08_20535	COG1252	NADH dehydrogenase
D9C08_20540	COG4837	Protein of unknown function (DUF1462)
D9C08_20545	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9C08_20550	COG0823	Involved in the tonB-independent uptake of proteins
D9C08_20550	COG4946	Tricorn protease homolog
D9C08_20550	COG1506	peptidase
D9C08_20555	COG0083	homoserine kinase activity
D9C08_20560	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9C08_20565	COG0460	homoserine dehydrogenase
D9C08_20570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C08_20575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C08_20580	COG0647	UMP catabolic process
D9C08_20585	COG2445	Protein of unknown function DUF86
D9C08_20590	COG4470	Protein conserved in bacteria
D9C08_20600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9C08_20605	COG0739	heme binding
D9C08_20615	COG3377	Domain of unknown function (DUF1805)
D9C08_20620	COG0737	Belongs to the 5'-nucleotidase family
D9C08_20625	COG0730	response to heat
D9C08_20630	COG1801	Protein of unknown function DUF72
D9C08_20640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C08_20645	COG2508	Transcriptional regulator
D9C08_20650	COG2233	PERMEase
D9C08_20655	COG2233	PERMEase
D9C08_20660	COG3648	Uricase
D9C08_20660	COG3195	allantoin biosynthetic process
D9C08_20665	COG2351	hydroxyisourate hydrolase activity
D9C08_20680	COG2080	2 iron, 2 sulfur cluster binding
D9C08_20685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9C08_20690	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9C08_20695	COG2068	MobA-Related Protein
D9C08_20700	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9C08_20705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9C08_20710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C08_20720	COG2356	endonuclease I
D9C08_20725	COG3842	ATPase activity
D9C08_20730	COG2188	Transcriptional regulator
D9C08_20735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C08_20745	COG1175	transmembrane transport
D9C08_20750	COG1653	transport
D9C08_20755	COG2222	sugar isomerase
D9C08_20760	COG0322	excinuclease ABC activity
D9C08_20765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C08_20785	COG0346	lactoylglutathione lyase activity
D9C08_20790	COG0640	Transcriptional regulator
D9C08_20800	COG5444	nuclease activity
D9C08_20810	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C08_20810	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_20815	COG4824	toxin secretion phage lysis holin
D9C08_20850	COG3953	SLT domain
D9C08_20850	COG5412	phage tail tape measure protein
D9C08_20945	COG0582	viral genome integration into host DNA
D9C08_21025	COG3800	Transcriptional regulator
D9C08_21025	COG1396	sequence-specific DNA binding
D9C08_21045	COG0719	Fe-S assembly protein
D9C08_21050	COG0822	iron-sulfur transferase activity
D9C08_21055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C08_21060	COG0719	Fe-S assembly protein
D9C08_21065	COG0396	ATPase activity
D9C08_21080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C08_21085	COG1464	Belongs to the NlpA lipoprotein family
D9C08_21090	COG2011	ABC-type metal ion transport system permease component
D9C08_21095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9C08_21105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C08_21110	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C08_21120	COG0509	glycine decarboxylation via glycine cleavage system
D9C08_21125	COG1393	Belongs to the ArsC family
D9C08_21130	COG1960	acyl-CoA dehydrogenase activity
D9C08_21135	COG0183	Belongs to the thiolase family
D9C08_21140	COG1024	Enoyl-CoA hydratase
D9C08_21140	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C08_21150	COG0506	proline dehydrogenase activity
D9C08_21160	COG5577	PFAM Coat F domain
D9C08_21165	COG1846	Transcriptional regulator
D9C08_21170	COG0477	Major facilitator Superfamily
D9C08_21175	COG1942	4-Oxalocrotonate Tautomerase
D9C08_21180	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_21185	COG0583	DNA-binding transcription factor activity
D9C08_21195	COG1120	ATPase activity
D9C08_21215	COG1131	(ABC) transporter
D9C08_21265	COG0783	Belongs to the Dps family
D9C08_21275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C08_21280	COG0745	RESPONSE REGULATOR receiver
D9C08_21285	COG2770	Histidine kinase
D9C08_21285	COG2205	protein histidine kinase activity
D9C08_21295	COG1309	transcriptional regulator
D9C08_21300	COG0114	fumarate hydratase activity
D9C08_21310	COG0697	spore germination
D9C08_21315	COG0814	amino acid
D9C08_21325	COG2197	response regulator
D9C08_21330	COG4585	Histidine kinase
D9C08_21335	COG4758	membrane
D9C08_21340	COG3595	metallopeptidase activity
D9C08_21345	COG1842	Phage shock protein A
D9C08_21350	COG4758	membrane
D9C08_21355	COG2814	Major facilitator Superfamily
D9C08_21360	COG2096	Adenosyltransferase
D9C08_21365	COG1120	ATPase activity
D9C08_21370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_21375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C08_21380	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_21385	COG3386	PFAM SMP-30 Gluconolaconase
D9C08_21390	COG2205	protein histidine kinase activity
D9C08_21395	COG0745	RESPONSE REGULATOR receiver
D9C08_21405	COG1191	sigma factor activity
D9C08_21415	COG2140	Oxalate decarboxylase
D9C08_21425	COG0577	efflux transmembrane transporter activity
D9C08_21430	COG1136	(ABC) transporter
D9C08_21435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C08_21440	COG1120	ATPase activity
D9C08_21445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_21450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C08_21455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C08_21465	COG0531	amino acid
D9C08_21480	COG1988	membrane-bound metal-dependent
D9C08_21485	COG1368	sulfuric ester hydrolase activity
D9C08_21490	COG1910	domain protein
D9C08_21495	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9C08_21500	COG4149	molybdate abc transporter
D9C08_21505	COG0656	L-ascorbic acid biosynthetic process
D9C08_21515	COG0025	NhaP-type Na H and K H
D9C08_21520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C08_21525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C08_21530	COG3973	AAA domain
D9C08_21540	COG2860	membrane
D9C08_21545	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9C08_21550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9C08_21555	COG2217	Heavy metal translocating P-type atpase
D9C08_21565	COG2217	Heavy metal translocating P-type atpase
D9C08_21570	COG2608	mercury ion transmembrane transporter activity
D9C08_21575	COG1937	Protein conserved in bacteria
D9C08_21580	COG0673	inositol 2-dehydrogenase activity
D9C08_21590	COG1289	transmembrane transporter activity
D9C08_21600	COG2076	Multidrug Resistance protein
D9C08_21605	COG1309	transcriptional regulator
D9C08_21610	COG1028	Short-chain dehydrogenase reductase Sdr
D9C08_21620	COG5444	nuclease activity
D9C08_21635	COG3409	Peptidoglycan-binding domain 1 protein
D9C08_21635	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C08_21640	COG4824	toxin secretion phage lysis holin
D9C08_21665	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C08_21665	COG3942	CHAP domain
D9C08_21780	COG0582	viral genome integration into host DNA
D9C08_21890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9C08_21895	COG0557	exoribonuclease II activity
D9C08_21900	COG1647	Serine aminopeptidase, S33
D9C08_21905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C08_21910	COG0596	Alpha beta hydrolase
D9C08_21915	COG1476	TRANSCRIPTIONal
D9C08_21920	COG1396	sequence-specific DNA binding
D9C08_21925	COG1396	sequence-specific DNA binding
D9C08_21930	COG1733	regulation of RNA biosynthetic process
D9C08_21935	COG0840	transmembrane signaling receptor activity
D9C08_21945	COG1174	glycine betaine transport
D9C08_21950	COG1732	Glycine betaine
D9C08_21955	COG1174	glycine betaine transport
D9C08_21960	COG0517	IMP dehydrogenase activity
D9C08_21960	COG1125	glycine betaine transport
D9C08_21965	COG1510	regulation of RNA biosynthetic process
D9C08_21970	COG1174	glycine betaine transport
D9C08_21975	COG1732	Glycine betaine
D9C08_21980	COG1174	glycine betaine transport
D9C08_21985	COG1125	glycine betaine transport
D9C08_21985	COG0517	IMP dehydrogenase activity
D9C08_21990	COG1510	regulation of RNA biosynthetic process
D9C08_21995	COG2095	MarC family integral membrane protein
D9C08_22005	COG3064	Membrane
D9C08_22010	COG4640	response to antibiotic
D9C08_22015	COG0456	acetyltransferase
D9C08_22020	COG0148	phosphopyruvate hydratase activity
D9C08_22025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9C08_22030	COG0149	triose-phosphate isomerase activity
D9C08_22035	COG0126	phosphoglycerate kinase activity
D9C08_22040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C08_22045	COG2390	Transcriptional regulator
D9C08_22050	COG2814	Major facilitator Superfamily
D9C08_22055	COG1609	Transcriptional regulator
D9C08_22060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C08_22070	COG0583	DNA-binding transcription factor activity
D9C08_22075	COG0697	spore germination
D9C08_22080	COG1113	amino acid transport
D9C08_22090	COG1556	Lactate utilization protein
D9C08_22095	COG1139	Iron-sulfur cluster binding protein
D9C08_22100	COG0247	lactate metabolic process
D9C08_22115	COG2197	response regulator
D9C08_22120	COG4585	Histidine kinase
D9C08_22125	COG0842	Transport permease protein
D9C08_22130	COG1131	(ABC) transporter
D9C08_22135	COG0596	Alpha beta hydrolase
D9C08_22140	COG2208	phosphoserine phosphatase activity
D9C08_22145	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9C08_22150	COG1874	Beta-galactosidase
D9C08_22155	COG3833	ABC-type maltose transport systems, permease component
D9C08_22160	COG1175	transmembrane transport
D9C08_22165	COG2182	Extracellular solute-binding protein
D9C08_22170	COG1609	Transcriptional regulator
D9C08_22175	COG2186	Transcriptional regulator
D9C08_22180	COG1620	l-lactate permease
D9C08_22195	COG5039	Polysaccharide pyruvyl transferase
D9C08_22200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C08_22205	COG0110	maltose O-acetyltransferase activity
D9C08_22210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9C08_22215	COG2244	polysaccharide biosynthetic process
D9C08_22220	COG1216	Glycosyl transferase, family 2
D9C08_22225	COG5039	Polysaccharide pyruvyl transferase
D9C08_22230	COG1216	Glycosyl transferase, family 2
D9C08_22240	COG0438	transferase activity, transferring glycosyl groups
D9C08_22245	COG1215	transferase activity, transferring glycosyl groups
D9C08_22250	COG0438	transferase activity, transferring glycosyl groups
D9C08_22255	COG1086	Polysaccharide biosynthesis protein
D9C08_22260	COG0489	protein tyrosine kinase activity
D9C08_22265	COG3944	biosynthesis protein
D9C08_22270	COG1396	sequence-specific DNA binding
D9C08_22275	COG2272	Belongs to the type-B carboxylesterase lipase family
D9C08_22285	COG3479	Phenolic acid decarboxylase
D9C08_22310	COG1621	beta-fructofuranosidase activity
D9C08_22315	COG1621	beta-fructofuranosidase activity
D9C08_22320	COG0531	amino acid
D9C08_22325	COG1309	transcriptional regulator
D9C08_22330	COG2076	Multidrug Resistance protein
D9C08_22335	COG2076	Multidrug Resistance protein
D9C08_22350	COG0740	serine-type endopeptidase activity
D9C08_22355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C08_22360	COG0366	Alpha amylase catalytic
D9C08_22365	COG1554	hydrolase, family 65, central catalytic
D9C08_22370	COG5521	maltodextrose utilization protein MalA
D9C08_22375	COG3833	ABC-type maltose transport systems, permease component
D9C08_22380	COG1175	transmembrane transport
D9C08_22385	COG2182	Extracellular solute-binding protein
D9C08_22390	COG0366	Alpha amylase catalytic
D9C08_22395	COG1609	Transcriptional regulator
D9C08_22400	COG1611	Belongs to the LOG family
D9C08_22405	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C08_22410	COG0659	secondary active sulfate transmembrane transporter activity
D9C08_22415	COG0288	reversible hydration of carbon dioxide
D9C08_22420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C08_22425	COG0577	efflux transmembrane transporter activity
D9C08_22430	COG1136	(ABC) transporter
D9C08_22435	COG5002	protein histidine kinase activity
D9C08_22440	COG0745	RESPONSE REGULATOR receiver
D9C08_22450	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9C08_22455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C08_22460	COG1481	regulation of sporulation
D9C08_22465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9C08_22470	COG1660	Displays ATPase and GTPase activities
D9C08_22475	COG1051	belongs to the nudix hydrolase family
D9C08_22480	COG0492	ferredoxin-NADP+ reductase activity
D9C08_22485	COG3883	PFAM NLP P60 protein
D9C08_22485	COG0791	NLP P60 protein
D9C08_22545	COG1136	(ABC) transporter
D9C08_22545	COG0577	efflux transmembrane transporter activity
D9C08_22595	COG0457	Tetratricopeptide repeat
D9C08_22640	COG1191	sigma factor activity
D9C08_22705	COG3328	transposase activity
D9C08_22755	COG2002	toxin-antitoxin pair type II binding
D9C08_22780	COG1674	ftsk spoiiie
D9C08_22780	COG1196	nuclear chromosome segregation
D9C08_22840	COG3328	transposase activity
D9C08_22875	COG3209	COG3209 Rhs family protein
D9C08_22900	COG0457	Tetratricopeptide repeat
D9C08_22910	COG2003	Belongs to the UPF0758 family
D9C08_22960	COG3764	Sortase (surface protein transpeptidase)
D9C08_23015	COG4086	secreted protein
D9C08_23110	COG2805	Type II/IV secretion system protein
D9C08_23175	COG0653	protein targeting
D9C08_23295	COG0457	Tetratricopeptide repeat
D9C08_23325	COG0457	Tetratricopeptide repeat