locus-tag	class	description
RP72_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RP72_00010	COG0592	DNA-directed DNA polymerase activity
RP72_00015	COG2501	S4 domain
RP72_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RP72_00030	COG0187	DNA topoisomerase II activity
RP72_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RP72_00070	COG0517	IMP dehydrogenase activity
RP72_00070	COG0516	GMP reductase activity
RP72_00075	COG1686	Belongs to the peptidase S11 family
RP72_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RP72_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RP72_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RP72_00100	COG1428	Deoxynucleoside kinase
RP72_00105	COG1428	Deoxynucleoside kinase
RP72_00110	COG1388	LysM domain
RP72_00110	COG3858	chitin binding
RP72_00115	COG1335	isochorismatase
RP72_00120	COG0590	tRNA wobble adenosine to inosine editing
RP72_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RP72_00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RP72_00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RP72_00180	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
RP72_00185	COG3853	Toxic anion resistance protein (TelA)
RP72_00190	COG1982	Orn Lys Arg decarboxylase major
RP72_00195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RP72_00200	COG3870	Protein conserved in bacteria
RP72_00205	COG1728	Protein conserved in bacteria
RP72_00210	COG0470	DNA polymerase III
RP72_00215	COG1774	PSP1 C-terminal conserved region
RP72_00220	COG4467	Involved in initiation control of chromosome replication
RP72_00225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RP72_00230	COG2827	Endonuclease containing a URI domain
RP72_00235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RP72_00245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RP72_00245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RP72_00250	COG0084	hydrolase, TatD family'
RP72_00255	COG3584	3D domain protein
RP72_00255	COG3583	domain protein
RP72_00260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RP72_00265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RP72_00275	COG4466	Protein conserved in bacteria
RP72_00285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RP72_00290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RP72_00295	COG0251	oxidation-reduction process
RP72_00300	COG2088	sporulation resulting in formation of a cellular spore
RP72_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RP72_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RP72_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RP72_00325	COG0193	aminoacyl-tRNA hydrolase activity
RP72_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RP72_00340	COG2002	toxin-antitoxin pair type II binding
RP72_00345	COG2244	polysaccharide biosynthetic process
RP72_00350	COG3956	TIGRFAM MazG family protein
RP72_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RP72_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RP72_00375	COG1098	S1 RNA binding domain
RP72_00390	COG2208	phosphoserine phosphatase activity
RP72_00395	COG2304	oxidoreductase activity
RP72_00400	COG0515	serine threonine protein kinase
RP72_00405	COG0037	tRNA processing
RP72_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RP72_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RP72_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RP72_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RP72_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RP72_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RP72_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
RP72_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RP72_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RP72_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RP72_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RP72_00470	COG1396	sequence-specific DNA binding
RP72_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RP72_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RP72_00565	COG4463	regulation of RNA biosynthetic process
RP72_00570	COG3880	PFAM UvrB UvrC protein
RP72_00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
RP72_00580	COG0542	response to heat
RP72_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RP72_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
RP72_00595	COG4956	integral membrane protein (PIN domain superfamily)
RP72_00600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RP72_00605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RP72_00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RP72_00620	COG1045	serine acetyltransferase
RP72_00625	COG0215	cysteine-tRNA ligase activity
RP72_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RP72_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RP72_00640	COG3688	RNA-binding protein containing a PIN domain
RP72_00645	COG1595	DNA-templated transcription, initiation
RP72_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RP72_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RP72_00660	COG0250	Participates in transcription elongation, termination and antitermination
RP72_00665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RP72_00670	COG0081	regulation of translation
RP72_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RP72_00680	COG0222	ribosome binding
RP72_00685	COG2813	Specifically methylates the guanine in position
RP72_00690	COG0085	RNA polymerase activity
RP72_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RP72_00700	COG1358	cellular component organization or biogenesis
RP72_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RP72_00710	COG0049	tRNA binding
RP72_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RP72_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RP72_00725	COG0596	Alpha beta hydrolase
RP72_00730	COG0051	transcription antitermination factor activity, RNA binding
RP72_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RP72_00740	COG0088	Forms part of the polypeptide exit tunnel
RP72_00745	COG0089	rRNA binding
RP72_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RP72_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RP72_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RP72_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RP72_00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RP72_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
RP72_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RP72_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RP72_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RP72_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RP72_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RP72_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RP72_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RP72_00825	COG1841	ribosomal large subunit assembly
RP72_00830	COG0200	Binds to the 23S rRNA
RP72_00835	COG0201	protein transport
RP72_00840	COG0563	adenylate kinase activity
RP72_00845	COG0024	Methionine aminopeptidase
RP72_00850	COG2163	COG2163 Ribosomal protein L14E L6E L27E
RP72_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RP72_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RP72_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RP72_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RP72_00875	COG0202	RNA polymerase activity
RP72_00880	COG0203	ribosomal protein L17
RP72_00885	COG1122	ATPase activity
RP72_00890	COG1122	ATPase activity
RP72_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RP72_00900	COG0101	tRNA pseudouridine synthase activity
RP72_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RP72_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RP72_00915	COG2226	methyltransferase
RP72_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
RP72_00930	COG0489	protein tyrosine kinase activity
RP72_00940	COG2194	sulfuric ester hydrolase activity
RP72_00945	COG0726	polysaccharide deacetylase
RP72_01030	COG0659	secondary active sulfate transmembrane transporter activity
RP72_01035	COG0385	Bile acid
RP72_01040	COG2819	hydrolase of the alpha beta superfamily
RP72_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RP72_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RP72_01060	COG2207	Transcriptional regulator
RP72_01065	COG3876	Protein conserved in bacteria
RP72_01070	COG1472	Belongs to the glycosyl hydrolase 3 family
RP72_01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RP72_01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_01080	COG1263	PTS System
RP72_01085	COG1737	Transcriptional regulator
RP72_01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RP72_01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_01100	COG1683	Conserved Protein
RP72_01130	COG1595	DNA-templated transcription, initiation
RP72_01135	COG5662	AntiSigma factor
RP72_01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RP72_01145	COG4856	YbbR-like protein
RP72_01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RP72_01155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RP72_01160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RP72_01165	COG2169	Transcriptional regulator
RP72_01170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RP72_01175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RP72_01180	COG3002	Belongs to the UPF0753 family
RP72_01185	COG0288	reversible hydration of carbon dioxide
RP72_01195	COG5609	conserved protein (DUF2294)
RP72_01205	COG0640	Transcriptional regulator
RP72_01210	COG2814	Major facilitator Superfamily
RP72_01215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RP72_01225	COG0535	radical SAM domain protein
RP72_01230	COG1266	CAAX protease self-immunity
RP72_01235	COG1131	(ABC) transporter
RP72_01245	COG1413	lyase activity
RP72_01250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_01255	COG0596	Alpha beta hydrolase
RP72_01260	COG0745	RESPONSE REGULATOR receiver
RP72_01265	COG0642	Histidine kinase
RP72_01275	COG0515	serine threonine protein kinase
RP72_01290	COG1113	amino acid transport
RP72_01305	COG2602	Beta-lactamase
RP72_01310	COG2124	cytochrome p450
RP72_01320	COG0531	amino acid
RP72_01325	COG0584	glycerophosphoryl diester phosphodiesterase
RP72_01330	COG2271	Major facilitator Superfamily
RP72_01340	COG1846	Transcriptional regulator
RP72_01340	COG0456	acetyltransferase
RP72_01345	COG2271	Major facilitator Superfamily
RP72_01360	COG3409	Peptidoglycan-binding domain 1 protein
RP72_01365	COG0697	spore germination
RP72_01370	COG2207	Transcriptional regulator
RP72_01370	COG1917	Cupin 2, conserved barrel domain protein
RP72_01375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RP72_01380	COG3591	Belongs to the peptidase S1B family
RP72_01390	COG0596	Alpha beta hydrolase
RP72_01395	COG1183	phosphatidylcholine synthase activity
RP72_01400	COG0586	Pfam SNARE associated Golgi protein
RP72_01405	COG0688	phosphatidylethanolamine metabolic process
RP72_01415	COG2312	Erythromycin esterase
RP72_01420	COG2207	Transcriptional regulator
RP72_01430	COG1301	dicarboxylic acid transport
RP72_01435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_01435	COG1263	PTS System
RP72_01435	COG2190	(PTS) system
RP72_01440	COG0363	glucosamine-6-phosphate deaminase activity
RP72_01455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RP72_01460	COG0833	amino acid
RP72_01465	COG2040	homocysteine
RP72_01475	COG1115	amino acid carrier protein
RP72_01480	COG2066	Belongs to the glutaminase family
RP72_01485	COG4191	Histidine kinase
RP72_01490	COG0784	Response regulator, receiver
RP72_01495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RP72_01500	COG1012	belongs to the aldehyde dehydrogenase family
RP72_01505	COG2271	Major facilitator Superfamily
RP72_01510	COG4948	Mandelate Racemase Muconate Lactonizing
RP72_01515	COG2186	Transcriptional regulator
RP72_01520	COG2721	sulfolactate sulfo-lyase activity
RP72_01525	COG3173	Aminoglycoside phosphotransferase
RP72_01535	COG0697	spore germination
RP72_01540	COG0745	RESPONSE REGULATOR receiver
RP72_01545	COG2205	protein histidine kinase activity
RP72_01550	COG1131	(ABC) transporter
RP72_01570	COG3773	Cell wall hydrolase
RP72_01575	COG2304	oxidoreductase activity
RP72_01585	COG3540	Alkaline phosphatase
RP72_01590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RP72_01605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RP72_01610	COG0477	Major facilitator Superfamily
RP72_01615	COG1309	transcriptional regulator
RP72_01620	COG0252	asparaginase activity
RP72_01625	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RP72_01630	COG1714	RDD family
RP72_01635	COG3012	SEC-C Motif Domain Protein
RP72_01635	COG1405	negative regulation of cell septum assembly
RP72_01640	COG3290	protein histidine kinase activity
RP72_01645	COG3279	Response regulator of the LytR AlgR family
RP72_01650	COG4555	ABC transporter
RP72_01655	COG1668	transmembrane transport
RP72_01660	COG0667	Aldo Keto reductase
RP72_01670	COG1595	DNA-templated transcription, initiation
RP72_01675	COG1595	DNA-templated transcription, initiation
RP72_01680	COG1876	peptidase activity
RP72_01685	COG0457	Tetratricopeptide repeat
RP72_01690	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_01695	COG0366	Alpha amylase catalytic
RP72_01700	COG0803	Belongs to the bacterial solute-binding protein 9 family
RP72_01705	COG1121	(ABC) transporter
RP72_01710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RP72_01715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RP72_01720	COG2310	stress, protein
RP72_01725	COG2310	stress, protein
RP72_01730	COG2310	stress, protein
RP72_01735	COG0861	Integral membrane protein TerC family
RP72_01745	COG3853	Toxic anion resistance protein (TelA)
RP72_01750	COG0477	Major facilitator Superfamily
RP72_01755	COG2814	Major facilitator Superfamily
RP72_01760	COG0640	Transcriptional regulator
RP72_01765	COG0517	IMP dehydrogenase activity
RP72_01765	COG4175	Glycine betaine
RP72_01770	COG4176	ABC-type proline glycine betaine transport system permease component
RP72_01775	COG2113	Glycine betaine
RP72_01780	COG1473	amidohydrolase
RP72_01785	COG1288	antiporter activity
RP72_01800	COG0366	Alpha amylase catalytic
RP72_01805	COG0039	L-malate dehydrogenase activity
RP72_01810	COG1620	l-lactate permease
RP72_01815	COG2814	Major facilitator Superfamily
RP72_01820	COG1846	Transcriptional regulator
RP72_01825	COG1280	lysine exporter protein (LysE YggA)
RP72_01830	COG3403	YqcI/YcgG family
RP72_01835	COG1113	amino acid transport
RP72_01840	COG3665	Urea carboxylase-associated protein
RP72_01845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RP72_01850	COG1660	Displays ATPase and GTPase activities
RP72_01855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RP72_01860	COG2226	methyltransferase
RP72_01865	COG0583	DNA-binding transcription factor activity
RP72_01870	COG3458	cephalosporin-C deacetylase activity
RP72_01875	COG3541	Predicted nucleotidyltransferase
RP72_01880	COG0506	proline dehydrogenase activity
RP72_01885	COG1012	belongs to the aldehyde dehydrogenase family
RP72_01895	COG2508	Transcriptional regulator
RP72_01900	COG3689	TIGRFAM TIGR03943 family protein
RP72_01905	COG0701	Predicted permease
RP72_01910	COG2267	carboxylic ester hydrolase activity
RP72_01915	COG0492	ferredoxin-NADP+ reductase activity
RP72_01920	COG1587	Uroporphyrinogen-III synthase
RP72_01920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RP72_01925	COG2146	nitrite reductase [NAD(P)H] activity
RP72_01930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RP72_01935	COG0243	molybdopterin cofactor binding
RP72_01940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RP72_01945	COG2223	nitrite transmembrane transporter activity
RP72_01950	COG1469	GTP cyclohydrolase I activity
RP72_01955	COG1376	ErfK ybiS ycfS ynhG family protein
RP72_01965	COG0523	cobalamin synthesis protein
RP72_01970	COG0765	amino acid transport
RP72_01975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RP72_01985	COG1714	RDD family
RP72_01995	COG2723	6-phospho-beta-galactosidase activity
RP72_02005	COG3209	COG3209 Rhs family protein
RP72_02010	COG3290	protein histidine kinase activity
RP72_02010	COG0840	transmembrane signaling receptor activity
RP72_02015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RP72_02020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RP72_02025	COG1733	regulation of RNA biosynthetic process
RP72_02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_02050	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RP72_02055	COG2814	Major facilitator Superfamily
RP72_02065	COG0697	spore germination
RP72_02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RP72_02080	COG2364	Membrane
RP72_02085	COG1126	abc transporter atp-binding protein
RP72_02090	COG0765	amino acid transport
RP72_02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RP72_02100	COG0583	DNA-binding transcription factor activity
RP72_02105	COG0163	prenyltransferase activity
RP72_02110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RP72_02125	COG0596	Alpha beta hydrolase
RP72_02130	COG3104	oligopeptide transport
RP72_02135	COG5434	Belongs to the glycosyl hydrolase 28 family
RP72_02145	COG0697	spore germination
RP72_02155	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RP72_02160	COG1136	(ABC) transporter
RP72_02165	COG0577	efflux transmembrane transporter activity
RP72_02170	COG0745	RESPONSE REGULATOR receiver
RP72_02175	COG3850	Histidine kinase
RP72_02175	COG5002	protein histidine kinase activity
RP72_02180	COG0457	Tetratricopeptide repeat
RP72_02200	COG0527	aspartate kinase activity
RP72_02205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_02210	COG4605	iron ion homeostasis
RP72_02215	COG4604	ABC transporter, ATP-binding protein
RP72_02220	COG4607	ABC-type enterochelin transport system periplasmic component
RP72_02225	COG2814	Major facilitator Superfamily
RP72_02230	COG1309	transcriptional regulator
RP72_02235	COG0778	Nitroreductase
RP72_02240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RP72_02245	COG0640	Transcriptional regulator
RP72_02250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RP72_02255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RP72_02260	COG1012	belongs to the aldehyde dehydrogenase family
RP72_02265	COG4975	Glucose uptake
RP72_02270	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_02275	COG4549	nuclear export factor GLE1
RP72_02280	COG1276	copper resistance
RP72_02280	COG2372	response to copper ion
RP72_02285	COG1349	DNA-binding transcription factor activity
RP72_02295	COG2213	PTS system mannitol-specific
RP72_02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_02305	COG0246	Mannitol dehydrogenase
RP72_02310	COG0473	3-isopropylmalate dehydrogenase activity
RP72_02315	COG0681	Belongs to the peptidase S26 family
RP72_02325	COG0412	Dienelactone hydrolase
RP72_02330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RP72_02340	COG0561	phosphatase activity
RP72_02345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RP72_02350	COG1914	H( )-stimulated, divalent metal cation uptake system
RP72_02355	COG4336	lyase activity
RP72_02360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RP72_02365	COG1984	allophanate hydrolase subunit 2
RP72_02370	COG1414	Transcriptional regulator
RP72_02375	COG2755	lipolytic protein G-D-S-L family
RP72_02385	COG2329	Antibiotic biosynthesis monooxygenase
RP72_02390	COG0768	penicillin binding
RP72_02395	COG4989	oxidoreductase activity
RP72_02400	COG3711	transcriptional antiterminator
RP72_02405	COG0318	PFAM AMP-dependent synthetase and ligase
RP72_02410	COG2226	methyltransferase
RP72_02415	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_02420	COG1917	Cupin 2, conserved barrel domain protein
RP72_02425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_02430	COG3871	stress protein (general stress protein 26)
RP72_02440	COG2814	Major facilitator Superfamily
RP72_02445	COG1522	sequence-specific DNA binding
RP72_02450	COG0551	DNA topoisomerase type I activity
RP72_02450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RP72_02455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RP72_02460	COG3706	GGDEF domain
RP72_02465	COG5298	Protein conserved in bacteria
RP72_02470	COG1215	transferase activity, transferring glycosyl groups
RP72_02480	COG0531	amino acid
RP72_02485	COG0494	nUDIX hydrolase
RP72_02490	COG0028	Belongs to the TPP enzyme family
RP72_02505	COG1914	H( )-stimulated, divalent metal cation uptake system
RP72_02510	COG2261	transglycosylase associated protein
RP72_02515	COG4876	unkown
RP72_02520	COG2217	Heavy metal translocating P-type atpase
RP72_02525	COG3729	General stress protein
RP72_02530	COG0662	Cupin 2, conserved barrel domain protein
RP72_02535	COG2329	Antibiotic biosynthesis monooxygenase
RP72_02540	COG3546	catalase activity
RP72_02545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RP72_02550	COG3290	protein histidine kinase activity
RP72_02555	COG4565	transcriptional regulatory protein
RP72_02560	COG1301	dicarboxylic acid transport
RP72_02565	COG0628	permease
RP72_02575	COG1131	(ABC) transporter
RP72_02580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RP72_02590	COG1960	acyl-CoA dehydrogenase activity
RP72_02605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RP72_02610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_02615	COG1181	Belongs to the D-alanine--D-alanine ligase family
RP72_02620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RP72_02625	COG0513	Belongs to the DEAD box helicase family
RP72_02630	COG3402	PFAM membrane-flanked domain
RP72_02635	COG3428	Bacterial PH domain
RP72_02640	COG0705	Rhomboid family
RP72_02645	COG0736	holo-[acyl-carrier-protein] synthase activity
RP72_02650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RP72_02655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RP72_02660	COG0864	Transcriptional regulator
RP72_02665	COG2337	Toxic component of a toxin-antitoxin (TA) module
RP72_02670	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_02675	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_02680	COG2172	sigma factor antagonist activity
RP72_02685	COG2208	phosphoserine phosphatase activity
RP72_02690	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_02695	COG2172	sigma factor antagonist activity
RP72_02700	COG1191	sigma factor activity
RP72_02705	COG2208	phosphoserine phosphatase activity
RP72_02720	COG1673	EVE domain
RP72_02725	COG1846	Transcriptional regulator
RP72_02730	COG2183	response to ionizing radiation
RP72_02740	COG3091	SprT-like family
RP72_02780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RP72_02785	COG1522	sequence-specific DNA binding
RP72_02790	COG1522	sequence-specific DNA binding
RP72_02795	COG1335	isochorismatase
RP72_02800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RP72_02805	COG2814	Major facilitator Superfamily
RP72_02825	COG0693	protein deglycase activity
RP72_02830	COG1278	Cold shock
RP72_02835	COG1329	Transcriptional regulator
RP72_02840	COG0697	spore germination
RP72_02845	COG2207	Transcriptional regulator
RP72_02845	COG1917	Cupin 2, conserved barrel domain protein
RP72_02850	COG0697	spore germination
RP72_02855	COG3708	Transcriptional regulator
RP72_02855	COG2207	Transcriptional regulator
RP72_02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RP72_02865	COG0477	Major facilitator Superfamily
RP72_02875	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RP72_02885	COG0697	spore germination
RP72_02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RP72_02895	COG2030	dehydratase
RP72_02900	COG3545	Serine hydrolase
RP72_02905	COG1733	regulation of RNA biosynthetic process
RP72_02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RP72_02915	COG1733	regulation of RNA biosynthetic process
RP72_02920	COG2249	NAD(P)H dehydrogenase (quinone) activity
RP72_02925	COG2814	Major facilitator Superfamily
RP72_02930	COG1309	transcriptional regulator
RP72_02940	COG0640	Transcriptional regulator
RP72_02945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RP72_02955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_02960	COG0697	spore germination
RP72_02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RP72_02970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RP72_02975	COG0640	Transcriptional regulator
RP72_02980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RP72_02995	COG4585	Histidine kinase
RP72_03000	COG2197	response regulator
RP72_03005	COG2409	Drug exporters of the RND superfamily
RP72_03010	COG0596	Alpha beta hydrolase
RP72_03015	COG1811	Na channel or pump
RP72_03020	COG4978	Transcriptional regulator
RP72_03020	COG0789	Transcriptional regulator
RP72_03025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RP72_03030	COG0778	Nitroreductase
RP72_03035	COG0346	lactoylglutathione lyase activity
RP72_03040	COG2259	Doxx family
RP72_03045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_03065	COG2323	membrane
RP72_03070	COG2323	membrane
RP72_03075	COG0071	Belongs to the small heat shock protein (HSP20) family
RP72_03090	COG1309	transcriptional regulator
RP72_03100	COG0456	acetyltransferase
RP72_03110	COG1113	amino acid transport
RP72_03115	COG2318	DinB family
RP72_03120	COG1846	Transcriptional regulator
RP72_03125	COG1033	growth of symbiont in host cell
RP72_03125	COG2409	Drug exporters of the RND superfamily
RP72_03130	COG0778	Nitroreductase
RP72_03135	COG1846	Transcriptional regulator
RP72_03140	COG2814	Major facilitator Superfamily
RP72_03145	COG0730	response to heat
RP72_03150	COG1802	Transcriptional regulator
RP72_03155	COG3858	chitin binding
RP72_03155	COG1388	LysM domain
RP72_03160	COG1819	glycosyl
RP72_03170	COG1785	Belongs to the alkaline phosphatase family
RP72_03175	COG5646	InterPro IPR014922
RP72_03185	COG0454	-acetyltransferase
RP72_03190	COG1078	dGTPase activity
RP72_03195	COG1388	LysM domain
RP72_03200	COG2814	Major facilitator Superfamily
RP72_03205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RP72_03210	COG1447	Phosphotransferase system cellobiose-specific component IIA
RP72_03215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RP72_03220	COG2723	6-phospho-beta-galactosidase activity
RP72_03225	COG2188	Transcriptional regulator
RP72_03230	COG1940	carbohydrate kinase activity
RP72_03235	COG1482	cell wall glycoprotein biosynthetic process
RP72_03240	COG4124	Belongs to the glycosyl hydrolase 26 family
RP72_03290	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RP72_03295	COG0802	atpase or kinase
RP72_03300	COG1214	PFAM Peptidase M22, glycoprotease
RP72_03305	COG0456	acetyltransferase
RP72_03310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RP72_03315	COG0488	(ABC) transporter
RP72_03320	COG0315	cyclic pyranopterin monophosphate synthase activity
RP72_03325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
RP72_03330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RP72_03335	COG0805	protein transport
RP72_03345	COG1266	CAAX protease self-immunity
RP72_03350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RP72_03355	COG0459	protein refolding
RP72_03370	COG3378	Phage plasmid primase P4 family
RP72_03385	COG0270	DNA (cytosine-5-)-methyltransferase activity
RP72_03390	COG0270	DNA (cytosine-5-)-methyltransferase activity
RP72_03395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RP72_03415	COG1401	restriction endodeoxyribonuclease activity
RP72_03430	COG1073	alpha beta
RP72_03435	COG0457	Tetratricopeptide repeat
RP72_03440	COG1063	alcohol dehydrogenase
RP72_03445	COG2211	Major facilitator Superfamily
RP72_03450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RP72_03455	COG1842	Phage shock protein A
RP72_03460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RP72_03465	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RP72_03470	COG4260	virion core protein, lumpy skin disease virus
RP72_03480	COG2814	Major facilitator Superfamily
RP72_03485	COG1063	alcohol dehydrogenase
RP72_03490	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RP72_03495	COG0823	Involved in the tonB-independent uptake of proteins
RP72_03510	COG2267	carboxylic ester hydrolase activity
RP72_03520	COG2132	Multicopper oxidase
RP72_03525	COG1113	amino acid transport
RP72_03535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RP72_03540	COG0714	Associated with various cellular activities
RP72_03545	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
RP72_03550	COG1305	Transglutaminase-like
RP72_03555	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RP72_03555	COG0519	Catalyzes the synthesis of GMP from XMP
RP72_03560	COG2252	PERMEase
RP72_03565	COG3064	Membrane
RP72_03575	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
RP72_03585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RP72_03590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RP72_03595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RP72_03600	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RP72_03605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RP72_03610	COG0047	phosphoribosylformylglycinamidine synthase activity
RP72_03615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RP72_03620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RP72_03625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RP72_03630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RP72_03635	COG0138	bifunctional purine biosynthesis protein purh
RP72_03640	COG0151	Belongs to the GarS family
RP72_03645	COG1522	sequence-specific DNA binding
RP72_03650	COG0531	amino acid
RP72_03660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RP72_03665	COG1470	cell adhesion involved in biofilm formation
RP72_03670	COG4496	protein, YerC YecD
RP72_03675	COG0069	glutamate synthase activity
RP72_03685	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
RP72_03690	COG0210	DNA helicase
RP72_03695	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RP72_03700	COG4851	CamS sex pheromone cAM373 precursor
RP72_03705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RP72_03710	COG1285	pathogenesis
RP72_03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RP72_03720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RP72_03725	COG0154	amidase activity
RP72_03730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RP72_03735	COG1309	transcriptional regulator
RP72_03740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RP72_03745	COG1597	lipid kinase activity
RP72_03750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RP72_03755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RP72_03760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RP72_03765	COG1002	Type II restriction enzyme, methylase subunits
RP72_03770	COG1061	Type III restriction enzyme res subunit
RP72_03775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RP72_03795	COG5444	nuclease activity
RP72_03800	COG3391	amine dehydrogenase activity
RP72_03805	COG0457	Tetratricopeptide repeat
RP72_03815	COG0217	transcriptional regulatory protein
RP72_03825	COG1309	transcriptional regulator
RP72_03830	COG3631	Ketosteroid isomerase-related protein
RP72_03835	COG0702	epimerase
RP72_03850	COG3546	catalase activity
RP72_03855	COG0454	-acetyltransferase
RP72_03865	COG5578	integral membrane protein
RP72_03870	COG2972	Histidine kinase
RP72_03875	COG4753	response regulator
RP72_03875	COG2207	Transcriptional regulator
RP72_03880	COG1653	transport
RP72_03885	COG1175	transmembrane transport
RP72_03890	COG0395	ABC-type sugar transport system, permease component
RP72_03895	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RP72_03900	COG2207	Transcriptional regulator
RP72_03905	COG2755	lipolytic protein G-D-S-L family
RP72_03915	COG5578	integral membrane protein
RP72_03920	COG3401	FG-GAP repeat protein
RP72_03925	COG3401	FG-GAP repeat protein
RP72_03930	COG2755	lipolytic protein G-D-S-L family
RP72_03935	COG1874	Beta-galactosidase
RP72_03945	COG1653	transport
RP72_03950	COG4209	transmembrane transport
RP72_03955	COG0395	ABC-type sugar transport system, permease component
RP72_03960	COG1486	melibiose metabolic process
RP72_03965	COG2323	membrane
RP72_03970	COG2329	Antibiotic biosynthesis monooxygenase
RP72_03975	COG0346	lactoylglutathione lyase activity
RP72_03990	COG5583	Uncharacterized small protein (DUF2292)
RP72_03995	COG0670	Belongs to the BI1 family
RP72_04000	COG0697	spore germination
RP72_04005	COG1846	Transcriptional regulator
RP72_04010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RP72_04020	COG2124	cytochrome p450
RP72_04020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RP72_04025	COG1368	sulfuric ester hydrolase activity
RP72_04030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RP72_04035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RP72_04040	COG1442	glycosyl transferase family 8
RP72_04045	COG1216	Glycosyl transferase, family 2
RP72_04050	COG1442	glycosyl transferase family 8
RP72_04055	COG2223	nitrite transmembrane transporter activity
RP72_04060	COG1011	Hydrolase
RP72_04065	COG0531	amino acid
RP72_04070	COG1012	belongs to the aldehyde dehydrogenase family
RP72_04075	COG0840	transmembrane signaling receptor activity
RP72_04080	COG0488	(ABC) transporter
RP72_04090	COG0789	Transcriptional regulator
RP72_04095	COG2814	Major facilitator Superfamily
RP72_04110	COG0488	(ABC) transporter
RP72_04115	COG0513	Belongs to the DEAD box helicase family
RP72_04120	COG0456	acetyltransferase
RP72_04125	COG2130	NADP-dependent
RP72_04140	COG2211	Major facilitator Superfamily
RP72_04145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RP72_04150	COG1120	ATPase activity
RP72_04155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_04160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_04165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RP72_04180	COG3866	Pectate lyase
RP72_04185	COG0471	metal ion transport
RP72_04190	COG3290	protein histidine kinase activity
RP72_04195	COG4565	transcriptional regulatory protein
RP72_04200	COG3181	Tripartite tricarboxylate transporter family receptor
RP72_04210	COG2851	Citrate transporter
RP72_04215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_04220	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
RP72_04225	COG1254	Belongs to the acylphosphatase family
RP72_04230	COG2258	MOSC domain
RP72_04250	COG0024	Methionine aminopeptidase
RP72_04255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_04255	COG1263	PTS System
RP72_04260	COG1368	sulfuric ester hydrolase activity
RP72_04270	COG1115	amino acid carrier protein
RP72_04275	COG0531	amino acid
RP72_04290	COG0697	spore germination
RP72_04295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_04295	COG1263	PTS System
RP72_04300	COG0366	Alpha amylase catalytic
RP72_04305	COG2188	Transcriptional regulator
RP72_04310	COG0778	Nitroreductase
RP72_04315	COG0737	Belongs to the 5'-nucleotidase family
RP72_04320	COG0693	protein deglycase activity
RP72_04325	COG2814	Major facilitator Superfamily
RP72_04330	COG4840	Belongs to the UPF0435 family
RP72_04335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RP72_04340	COG4980	gas vesicle protein
RP72_04345	COG1295	ribonuclease BN
RP72_04355	COG0477	Major facilitator Superfamily
RP72_04365	COG0387	Pfam Sodium calcium exchanger
RP72_04375	COG0668	transmembrane transport
RP72_04380	COG0535	radical SAM domain protein
RP72_04390	COG0726	polysaccharide deacetylase
RP72_04395	COG2084	Dehydrogenase
RP72_04400	COG0598	Magnesium transport protein CorA
RP72_04405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RP72_04410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RP72_04420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RP72_04425	COG4637	Psort location Cytoplasmic, score
RP72_04435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RP72_04440	COG0022	dehydrogenase e1 component
RP72_04445	COG0508	dehydrogenase complex catalyzes the overall conversion of
RP72_04450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RP72_04455	COG3284	Transcriptional regulator
RP72_04465	COG1742	UPF0060 membrane protein
RP72_04490	COG4842	Belongs to the WXG100 family
RP72_04495	COG1486	melibiose metabolic process
RP72_04500	COG1737	Transcriptional regulator
RP72_04505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_04505	COG1263	PTS System
RP72_04510	COG1132	(ABC) transporter
RP72_04515	COG1132	(ABC) transporter
RP72_04520	COG2259	Doxx family
RP72_04525	COG2514	catechol 2,3-dioxygenase activity
RP72_04530	COG4977	sequence-specific DNA binding
RP72_04530	COG1917	Cupin 2, conserved barrel domain protein
RP72_04535	COG2814	Major facilitator Superfamily
RP72_04540	COG1082	Xylose isomerase domain protein TIM barrel
RP72_04545	COG0673	inositol 2-dehydrogenase activity
RP72_04550	COG4585	Histidine kinase
RP72_04555	COG2197	response regulator
RP72_04560	COG1131	(ABC) transporter
RP72_04565	COG0842	Transport permease protein
RP72_04565	COG1511	domain protein
RP72_04570	COG0842	Transport permease protein
RP72_04575	COG1695	Transcriptional regulator
RP72_04580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RP72_04585	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
RP72_04590	COG1309	transcriptional regulator
RP72_04595	COG2814	Major facilitator Superfamily
RP72_04600	COG2318	DinB family
RP72_04605	COG2814	Major facilitator Superfamily
RP72_04610	COG1846	Transcriptional regulator
RP72_04615	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RP72_04615	COG0392	lysyltransferase activity
RP72_04620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RP72_04625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_04630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_04635	COG0384	phenazine biosynthesis protein PhzF
RP72_04640	COG0778	Nitroreductase
RP72_04655	COG1090	epimerase
RP72_04660	COG2137	regulation of response to DNA damage stimulus
RP72_04675	COG2814	Major facilitator Superfamily
RP72_04690	COG3103	Sh3 type 3 domain protein
RP72_04695	COG5658	integral membrane protein
RP72_04700	COG0596	Alpha beta hydrolase
RP72_04705	COG0463	Glycosyl transferase, family 2
RP72_04710	COG4485	Bacterial membrane protein, YfhO
RP72_04715	COG1988	membrane-bound metal-dependent
RP72_04720	COG1194	a g-specific adenine glycosylase
RP72_04730	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_04745	COG3557	Belongs to the UPF0374 family
RP72_04750	COG1132	(ABC) transporter
RP72_04755	COG4129	membrane
RP72_04760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RP72_04765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RP72_04770	COG0735	belongs to the Fur family
RP72_04885	COG4326	sporulation control protein
RP72_04895	COG5577	PFAM Coat F domain
RP72_04900	COG3340	Belongs to the peptidase S51 family
RP72_04905	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RP72_04910	COG0277	FAD linked oxidase domain protein
RP72_04920	COG0753	catalase activity
RP72_04925	COG1116	anion transmembrane transporter activity
RP72_04930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RP72_04935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RP72_04940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RP72_04950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RP72_04960	COG1476	TRANSCRIPTIONal
RP72_04970	COG3382	B3 4 domain protein
RP72_04975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RP72_04985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RP72_04990	COG0789	Transcriptional regulator
RP72_04995	COG1664	Polymer-forming cytoskeletal
RP72_05000	COG1664	Polymer-forming cytoskeletal
RP72_05005	COG2766	serine protein kinase
RP72_05010	COG2718	Belongs to the UPF0229 family
RP72_05020	COG1846	Transcriptional regulator
RP72_05025	COG1566	PFAM secretion protein HlyD family protein
RP72_05030	COG2814	Major facilitator Superfamily
RP72_05035	COG0655	NAD(P)H dehydrogenase (quinone) activity
RP72_05050	COG1725	Transcriptional regulator
RP72_05055	COG1131	(ABC) transporter
RP72_05060	COG1131	(ABC) transporter
RP72_05065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RP72_05070	COG1278	Cold shock
RP72_05080	COG1464	Belongs to the NlpA lipoprotein family
RP72_05085	COG3706	GGDEF domain
RP72_05090	COG1823	symporter activity
RP72_05110	COG5577	PFAM Coat F domain
RP72_05115	COG1525	nuclease
RP72_05115	COG4085	toxin activity
RP72_05115	COG0737	Belongs to the 5'-nucleotidase family
RP72_05120	COG3764	Sortase (surface protein transpeptidase)
RP72_05125	COG0564	pseudouridine synthase activity
RP72_05135	COG0517	IMP dehydrogenase activity
RP72_05140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RP72_05145	COG3153	acetyltransferase
RP72_05145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RP72_05150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RP72_05155	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RP72_05160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RP72_05165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RP72_05170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RP72_05175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RP72_05180	COG2203	Gaf domain
RP72_05180	COG4585	Histidine kinase
RP72_05185	COG2197	response regulator
RP72_05190	COG0431	NADPH-dependent FMN reductase
RP72_05205	COG1388	LysM domain
RP72_05205	COG0791	NLP P60 protein
RP72_05210	COG1959	2 iron, 2 sulfur cluster binding
RP72_05215	COG0668	transmembrane transport
RP72_05220	COG2719	SpoVR family
RP72_05225	COG1785	Belongs to the alkaline phosphatase family
RP72_05230	COG1388	LysM domain
RP72_05230	COG0791	NLP P60 protein
RP72_05235	COG0583	DNA-binding transcription factor activity
RP72_05240	COG0372	Belongs to the citrate synthase family
RP72_05245	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_05250	COG0531	amino acid
RP72_05255	COG0733	neurotransmitter:sodium symporter activity
RP72_05260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RP72_05265	COG0456	acetyltransferase
RP72_05280	COG1595	DNA-templated transcription, initiation
RP72_05285	COG0667	Aldo Keto reductase
RP72_05290	COG0204	Acyl-transferase
RP72_05295	COG1253	flavin adenine dinucleotide binding
RP72_05300	COG0789	Transcriptional regulator
RP72_05305	COG0436	Aminotransferase
RP72_05310	COG1253	flavin adenine dinucleotide binding
RP72_05315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RP72_05320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RP72_05325	COG0584	glycerophosphoryl diester phosphodiesterase
RP72_05335	COG0668	transmembrane transport
RP72_05340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RP72_05345	COG0726	polysaccharide deacetylase
RP72_05350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RP72_05355	COG1757	Na H antiporter
RP72_05360	COG0589	response to stress
RP72_05370	COG1132	(ABC) transporter
RP72_05375	COG1132	(ABC) transporter
RP72_05380	COG0702	epimerase
RP72_05395	COG0189	ligase activity
RP72_05400	COG0189	ligase activity
RP72_05405	COG4399	Belongs to the UPF0754 family
RP72_05410	COG3679	Belongs to the UPF0342 family
RP72_05415	COG4335	DNA alkylation repair
RP72_05420	COG0561	phosphatase activity
RP72_05425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RP72_05430	COG0475	glutathione-regulated potassium exporter activity
RP72_05435	COG0490	domain, Protein
RP72_05445	COG1024	Enoyl-CoA hydratase
RP72_05455	COG4152	abc transporter atp-binding protein
RP72_05460	COG1668	transmembrane transport
RP72_05465	COG0420	3'-5' exonuclease activity
RP72_05470	COG4717	serine-type aminopeptidase activity
RP72_05475	COG3481	metal-dependent phosphohydrolase, HD sub domain
RP72_05485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RP72_05510	COG1846	Transcriptional regulator
RP72_05515	COG4980	gas vesicle protein
RP72_05530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RP72_05535	COG0537	adenosine 5'-monophosphoramidase activity
RP72_05540	COG1131	(ABC) transporter
RP72_05545	COG4473	ABC transporter
RP72_05555	COG1473	amidohydrolase
RP72_05560	COG3069	C4-dicarboxylate transmembrane transporter activity
RP72_05570	COG2329	Antibiotic biosynthesis monooxygenase
RP72_05575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RP72_05580	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RP72_05595	COG1309	transcriptional regulator
RP72_05600	COG1511	domain protein
RP72_05605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RP72_05610	COG4377	Putative membrane peptidase family (DUF2324)
RP72_05620	COG1363	Peptidase, m42
RP72_05625	COG4405	Protein conserved in bacteria
RP72_05630	COG1301	dicarboxylic acid transport
RP72_05640	COG1234	tRNA 3'-trailer cleavage
RP72_05645	COG0095	Lipoate-protein ligase
RP72_05650	COG0702	epimerase
RP72_05655	COG0318	PFAM AMP-dependent synthetase and ligase
RP72_05665	COG0501	Belongs to the peptidase M48B family
RP72_05670	COG1404	Belongs to the peptidase S8 family
RP72_05675	COG0456	acetyltransferase
RP72_05680	COG0604	alcohol dehydrogenase
RP72_05685	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RP72_05690	COG0406	alpha-ribazole phosphatase activity
RP72_05695	COG0183	Belongs to the thiolase family
RP72_05700	COG0318	PFAM AMP-dependent synthetase and ligase
RP72_05705	COG1268	BioY protein
RP72_05710	COG0840	transmembrane signaling receptor activity
RP72_05715	COG0723	plastoquinol--plastocyanin reductase activity
RP72_05715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RP72_05720	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_05730	COG4903	ComK protein
RP72_05735	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_05745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RP72_05760	COG0398	Pfam SNARE associated Golgi protein
RP72_05765	COG0681	Belongs to the peptidase S26 family
RP72_05770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RP72_05775	COG1846	Transcriptional regulator
RP72_05780	COG0738	Major facilitator superfamily
RP72_05785	COG0673	inositol 2-dehydrogenase activity
RP72_05790	COG0561	phosphatase activity
RP72_05795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RP72_05800	COG1609	Transcriptional regulator
RP72_05805	COG3180	Ammonia monooxygenase
RP72_05810	COG2814	Major facilitator Superfamily
RP72_05810	COG0477	Major facilitator Superfamily
RP72_05815	COG4533	DNA binding
RP72_05825	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RP72_05830	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RP72_05835	COG1074	ATP-dependent DNA helicase activity
RP72_05840	COG0420	3'-5' exonuclease activity
RP72_05845	COG0419	ATPase involved in DNA repair
RP72_05850	COG1403	HNH endonuclease
RP72_05895	COG5337	Spore coat protein CotH
RP72_05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
RP72_05910	COG1404	Belongs to the peptidase S8 family
RP72_05920	COG0367	asparagine synthase
RP72_05925	COG2318	DinB family
RP72_05930	COG1562	ergosterol biosynthetic process
RP72_05935	COG0534	Mate efflux family protein
RP72_05940	COG2207	Transcriptional regulator
RP72_05940	COG1917	Cupin 2, conserved barrel domain protein
RP72_05945	COG1609	Transcriptional regulator
RP72_05950	COG0673	inositol 2-dehydrogenase activity
RP72_05955	COG2318	DinB family
RP72_05960	COG1279	arginine transmembrane transporter activity
RP72_05965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RP72_05970	COG1357	PFAM Pentapeptide repeats (8 copies)
RP72_05975	COG2267	carboxylic ester hydrolase activity
RP72_05980	COG0529	Catalyzes the synthesis of activated sulfate
RP72_05985	COG2046	Belongs to the sulfate adenylyltransferase family
RP72_05990	COG0175	sulfate reduction
RP72_05995	COG2045	Belongs to the ComB family
RP72_06000	COG1809	phosphosulfolactate synthase activity
RP72_06005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RP72_06010	COG4948	Mandelate Racemase Muconate Lactonizing
RP72_06015	COG2814	Major facilitator Superfamily
RP72_06020	COG0454	-acetyltransferase
RP72_06025	COG2153	protein acetylation
RP72_06030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RP72_06030	COG0646	methionine synthase
RP72_06035	COG1666	GTP binding
RP72_06040	COG2996	Protein conserved in bacteria
RP72_06060	COG1695	Transcriptional regulator
RP72_06075	COG3227	Zinc metalloprotease (Elastase)
RP72_06080	COG1307	EDD domain protein, DegV family
RP72_06085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RP72_06105	COG0561	phosphatase activity
RP72_06110	COG1073	alpha beta
RP72_06115	COG2151	metal-sulfur cluster biosynthetic enzyme
RP72_06125	COG0277	FAD linked oxidase domain protein
RP72_06130	COG2271	Major facilitator Superfamily
RP72_06135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RP72_06150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RP72_06155	COG0505	Belongs to the CarA family
RP72_06160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RP72_06165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RP72_06180	COG2267	carboxylic ester hydrolase activity
RP72_06190	COG1744	ABC transporter substrate-binding protein PnrA-like
RP72_06205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RP72_06210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RP72_06215	COG5504	Zn-dependent protease
RP72_06220	COG0444	Belongs to the ABC transporter superfamily
RP72_06225	COG4608	Belongs to the ABC transporter superfamily
RP72_06235	COG0601	transmembrane transport
RP72_06240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RP72_06250	COG0180	Tryptophanyl-tRNA synthetase
RP72_06255	COG4166	transmembrane transport
RP72_06260	COG0601	transmembrane transport
RP72_06265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RP72_06270	COG0444	Belongs to the ABC transporter superfamily
RP72_06275	COG4608	Belongs to the ABC transporter superfamily
RP72_06280	COG2814	Major facilitator Superfamily
RP72_06285	COG0456	acetyltransferase
RP72_06290	COG1393	Belongs to the ArsC family
RP72_06295	COG0861	Integral membrane protein TerC family
RP72_06300	COG4862	establishment of competence for transformation
RP72_06305	COG4469	Competence protein
RP72_06310	COG1164	Oligoendopeptidase f
RP72_06330	COG2346	COG2346, Truncated hemoglobins
RP72_06335	COG0741	lytic transglycosylase activity
RP72_06340	COG4116	CYTH
RP72_06350	COG2357	RelA SpoT domain protein
RP72_06355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RP72_06360	COG0564	pseudouridine synthase activity
RP72_06365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RP72_06370	COG0475	glutathione-regulated potassium exporter activity
RP72_06370	COG0569	domain protein
RP72_06375	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RP72_06380	COG0352	thiamine-phosphate diphosphorylase activity
RP72_06385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RP72_06390	COG2104	thiamine diphosphate biosynthetic process
RP72_06395	COG2022	thiamine diphosphate biosynthetic process
RP72_06400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RP72_06405	COG0351	phosphomethylpyrimidine kinase
RP72_06410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RP72_06470	COG0210	DNA helicase
RP72_06480	COG2153	protein acetylation
RP72_06485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RP72_06490	COG2382	esterase
RP72_06495	COG0626	cystathionine gamma-synthase activity
RP72_06500	COG0626	cystathionine gamma-synthase activity
RP72_06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_06510	COG5505	Protein of unknown function (DUF819)
RP72_06545	COG3677	Transposase
RP72_06560	COG5484	DNA packaging
RP72_06565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RP72_06570	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_06580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_06580	COG3711	transcriptional antiterminator
RP72_06585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RP72_06585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RP72_06585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_06590	COG1482	cell wall glycoprotein biosynthetic process
RP72_06600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_06610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RP72_06625	COG0109	protoheme IX farnesyltransferase activity
RP72_06635	COG0726	polysaccharide deacetylase
RP72_06655	COG5504	Zn-dependent protease
RP72_06660	COG2205	protein histidine kinase activity
RP72_06670	COG3383	formate dehydrogenase (NAD+) activity
RP72_06675	COG2427	Protein of unknown function (DUF1641)
RP72_06685	COG1051	belongs to the nudix hydrolase family
RP72_06695	COG2124	cytochrome p450
RP72_06700	COG1819	glycosyl
RP72_06710	COG1587	Uroporphyrinogen-III synthase
RP72_06715	COG0390	transport system, permease component
RP72_06720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RP72_06725	COG0697	spore germination
RP72_06730	COG4297	protein containing double-stranded beta helix domain
RP72_06740	COG1252	NADH dehydrogenase
RP72_06745	COG1904	glucuronate isomerase
RP72_06750	COG2211	Major facilitator Superfamily
RP72_06755	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
RP72_06760	COG1063	alcohol dehydrogenase
RP72_06765	COG1312	Catalyzes the dehydration of D-mannonate
RP72_06770	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_06775	COG2271	Major facilitator Superfamily
RP72_06780	COG1609	Transcriptional regulator
RP72_06785	COG0246	Mannitol dehydrogenase
RP72_06790	COG2721	sulfolactate sulfo-lyase activity
RP72_06795	COG0730	response to heat
RP72_06800	COG2318	DinB family
RP72_06805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RP72_06810	COG0457	Tetratricopeptide repeat
RP72_06820	COG2350	Protein conserved in bacteria
RP72_06825	COG3409	Peptidoglycan-binding domain 1 protein
RP72_06825	COG5632	N-Acetylmuramoyl-L-alanine amidase
RP72_06825	COG1388	LysM domain
RP72_06835	COG4195	phage-related replication protein
RP72_06840	COG3546	catalase activity
RP72_06845	COG2856	Zn peptidase
RP72_06850	COG1396	sequence-specific DNA binding
RP72_06860	COG1522	sequence-specific DNA binding
RP72_06865	COG1484	DNA-dependent DNA replication
RP72_06890	COG1595	DNA-templated transcription, initiation
RP72_06895	COG5484	DNA packaging
RP72_06895	COG3728	DNA packaging
RP72_06900	COG1783	phage Terminase large subunit
RP72_06905	COG5518	Phage portal protein
RP72_06910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RP72_06915	COG4653	Phage capsid family
RP72_06965	COG3953	SLT domain
RP72_06965	COG5412	phage tail tape measure protein
RP72_06970	COG1652	LysM domain
RP72_06975	COG4193	domain, Protein
RP72_06985	COG3628	GPW Gp25 family protein
RP72_06990	COG3299	homolog of phage Mu protein gp47
RP72_06995	COG3778	Protein conserved in bacteria
RP72_07035	COG3409	Peptidoglycan-binding domain 1 protein
RP72_07035	COG5632	N-Acetylmuramoyl-L-alanine amidase
RP72_07050	COG0306	phosphate transporter
RP72_07055	COG1392	Phosphate transport regulator
RP72_07060	COG0531	amino acid
RP72_07065	COG0346	lactoylglutathione lyase activity
RP72_07070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RP72_07075	COG0463	Glycosyl transferase, family 2
RP72_07085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RP72_07090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RP72_07095	COG2362	D-Aminopeptidase
RP72_07100	COG0601	transmembrane transport
RP72_07105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RP72_07110	COG0444	Belongs to the ABC transporter superfamily
RP72_07115	COG4166	transmembrane transport
RP72_07120	COG1619	proteins homologs of microcin C7 resistance protein MccF
RP72_07125	COG4948	Mandelate Racemase Muconate Lactonizing
RP72_07130	COG0791	NLP P60 protein
RP72_07135	COG4608	Belongs to the ABC transporter superfamily
RP72_07140	COG2706	6-phosphogluconolactonase activity
RP72_07145	COG1834	amidinotransferase
RP72_07150	COG1607	acyl-coa hydrolase
RP72_07155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RP72_07155	COG1017	nitric oxide dioxygenase activity
RP72_07165	COG2323	membrane
RP72_07170	COG2318	DinB family
RP72_07175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_07180	COG2076	Multidrug Resistance protein
RP72_07185	COG2076	Multidrug Resistance protein
RP72_07190	COG0788	formyltetrahydrofolate deformylase activity
RP72_07195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RP72_07200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RP72_07205	COG1764	response to oxidative stress
RP72_07210	COG1846	Transcriptional regulator
RP72_07215	COG1764	response to oxidative stress
RP72_07225	COG0590	tRNA wobble adenosine to inosine editing
RP72_07230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RP72_07235	COG1404	Belongs to the peptidase S8 family
RP72_07240	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_07245	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RP72_07250	COG1122	ATPase activity
RP72_07255	COG4721	ABC-type cobalt transport system, permease component
RP72_07265	COG0745	RESPONSE REGULATOR receiver
RP72_07270	COG3850	Histidine kinase
RP72_07270	COG5002	protein histidine kinase activity
RP72_07275	COG3212	peptidase
RP72_07280	COG3212	peptidase
RP72_07300	COG2239	Acts as a magnesium transporter
RP72_07305	COG0789	Transcriptional regulator
RP72_07320	COG1846	Transcriptional regulator
RP72_07325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RP72_07330	COG0726	polysaccharide deacetylase
RP72_07335	COG1408	metallophosphoesterase
RP72_07345	COG0463	Glycosyl transferase, family 2
RP72_07350	COG3285	dna ligase
RP72_07350	COG1793	dna ligase
RP72_07355	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RP72_07360	COG5001	Diguanylate cyclase
RP72_07360	COG3300	MHYT domain
RP72_07365	COG0586	Pfam SNARE associated Golgi protein
RP72_07370	COG0861	Integral membrane protein TerC family
RP72_07375	COG1191	sigma factor activity
RP72_07395	COG0501	Belongs to the peptidase M48B family
RP72_07400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RP72_07415	COG3594	Acyltransferase
RP72_07420	COG5002	protein histidine kinase activity
RP72_07425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RP72_07435	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RP72_07440	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
RP72_07445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RP72_07450	COG0436	Aminotransferase
RP72_07455	COG1850	ribulose-bisphosphate carboxylase activity
RP72_07460	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
RP72_07465	COG0235	Class ii aldolase
RP72_07470	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
RP72_07475	COG3339	Conserved Protein
RP72_07490	COG3852	Histidine kinase
RP72_07495	COG1846	Transcriptional regulator
RP72_07500	COG1360	Flagellar Motor Protein
RP72_07505	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RP72_07510	COG0542	response to heat
RP72_07515	COG3949	Membrane
RP72_07520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RP72_07525	COG0720	synthase
RP72_07530	COG0602	queuosine metabolic process
RP72_07535	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RP72_07540	COG1733	regulation of RNA biosynthetic process
RP72_07545	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_07550	COG1388	LysM domain
RP72_07550	COG4641	Protein conserved in bacteria
RP72_07555	COG1388	LysM domain
RP72_07560	COG3858	chitin binding
RP72_07565	COG3858	chitin binding
RP72_07575	COG4873	Protein conserved in bacteria
RP72_07590	COG3773	Cell wall hydrolase
RP72_07595	COG2244	polysaccharide biosynthetic process
RP72_07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_07605	COG2217	Heavy metal translocating P-type atpase
RP72_07615	COG0006	proline dipeptidase activity
RP72_07625	COG1609	Transcriptional regulator
RP72_07630	COG3711	transcriptional antiterminator
RP72_07635	COG2190	(PTS) system
RP72_07635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_07635	COG1263	PTS System
RP72_07640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_07645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RP72_07655	COG1533	DNA photolyase activity
RP72_07660	COG0456	acetyltransferase
RP72_07665	COG0840	transmembrane signaling receptor activity
RP72_07670	COG2084	Dehydrogenase
RP72_07675	COG2340	Cysteine-rich secretory protein family
RP72_07680	COG0768	penicillin binding
RP72_07685	COG4191	Histidine kinase
RP72_07690	COG0436	Aminotransferase
RP72_07700	COG0784	Response regulator, receiver
RP72_07700	COG0835	chemotaxis
RP72_07710	COG2814	Major facilitator Superfamily
RP72_07715	COG1376	ErfK ybiS ycfS ynhG family protein
RP72_07720	COG1408	metallophosphoesterase
RP72_07725	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_07730	COG3409	Peptidoglycan-binding domain 1 protein
RP72_07735	COG3409	Peptidoglycan-binding domain 1 protein
RP72_07745	COG2200	EAL domain
RP72_07755	COG4703	Protein of unknown function (DUF1797)
RP72_07760	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
RP72_07770	COG0517	IMP dehydrogenase activity
RP72_07775	COG0583	DNA-binding transcription factor activity
RP72_07780	COG0716	FMN binding
RP72_07790	COG0716	FMN binding
RP72_07795	COG2171	N-acyltransferase activity
RP72_07800	COG1473	amidohydrolase
RP72_07810	COG0668	transmembrane transport
RP72_07815	COG0450	alkyl hydroperoxide reductase
RP72_07820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_07835	COG0746	molybdenum cofactor guanylyltransferase activity
RP72_07840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RP72_07845	COG0303	'Molybdopterin
RP72_07850	COG1763	Mo-molybdopterin cofactor biosynthetic process
RP72_07855	COG0314	molybdopterin synthase activity
RP72_07860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RP72_07865	COG1132	(ABC) transporter
RP72_07870	COG1132	(ABC) transporter
RP72_07880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RP72_07885	COG1136	(ABC) transporter
RP72_07890	COG0577	efflux transmembrane transporter activity
RP72_07895	COG1349	DNA-binding transcription factor activity
RP72_07900	COG1105	Belongs to the carbohydrate kinase PfkB family
RP72_07905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RP72_07905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RP72_07905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_07910	COG0681	Belongs to the peptidase S26 family
RP72_07920	COG0488	(ABC) transporter
RP72_07925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RP72_07930	COG2309	aminopeptidase activity
RP72_07940	COG1077	Cell shape determining protein MreB Mrl
RP72_07945	COG2002	toxin-antitoxin pair type II binding
RP72_07950	COG3852	Histidine kinase
RP72_07955	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RP72_07955	COG2105	PFAM AIG2 family protein
RP72_07960	COG0569	domain protein
RP72_07965	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RP72_07970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RP72_07980	COG0561	phosphatase activity
RP72_07985	COG0242	peptide deformylase activity
RP72_07995	COG0497	DNA recombination
RP72_08000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RP72_08005	COG0022	dehydrogenase e1 component
RP72_08010	COG0508	dehydrogenase complex catalyzes the overall conversion of
RP72_08015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RP72_08020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_08025	COG1982	Orn Lys Arg decarboxylase major
RP72_08030	COG4476	Belongs to the UPF0223 family
RP72_08035	COG4493	Belongs to the UPF0637 family
RP72_08045	COG0483	inositol monophosphate 1-phosphatase activity
RP72_08055	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RP72_08075	COG1595	DNA-templated transcription, initiation
RP72_08105	COG4896	Protein conserved in bacteria
RP72_08115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RP72_08120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RP72_08125	COG2066	Belongs to the glutaminase family
RP72_08130	COG4838	Belongs to the UPF0358 family
RP72_08135	COG0772	Belongs to the SEDS family
RP72_08140	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RP72_08145	COG1612	heme a metabolic process
RP72_08150	COG0109	protoheme IX farnesyltransferase activity
RP72_08155	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RP72_08155	COG2010	Cytochrome c
RP72_08160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RP72_08165	COG1845	cytochrome c oxidase, subunit III
RP72_08170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RP72_08175	COG3336	cytochrome c oxidase
RP72_08185	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
RP72_08190	COG2340	Cysteine-rich secretory protein family
RP72_08205	COG3679	Belongs to the UPF0342 family
RP72_08210	COG4471	UPF0298 protein
RP72_08215	COG0742	ribosomal rna small subunit methyltransferase
RP72_08220	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RP72_08225	COG3314	Sporulation integral membrane protein YlbJ
RP72_08230	COG1752	Esterase of the alpha-beta hydrolase superfamily
RP72_08235	COG3480	Lon protease (S16) C-terminal proteolytic domain
RP72_08240	COG1323	Belongs to the UPF0348 family
RP72_08250	COG1399	metal-binding, possibly nucleic acid-binding protein
RP72_08255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RP72_08265	COG0454	-acetyltransferase
RP72_08270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RP72_08275	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
RP72_08280	COG2001	Belongs to the MraZ family
RP72_08285	COG0275	rRNA processing
RP72_08290	COG4839	cell division protein FtsL
RP72_08305	COG0768	penicillin binding
RP72_08315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RP72_08325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RP72_08330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RP72_08335	COG0772	Belongs to the SEDS family
RP72_08340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RP72_08345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RP72_08350	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RP72_08355	COG3879	Bacterial protein of unknown function (DUF881)
RP72_08360	COG3879	Bacterial protein of unknown function (DUF881)
RP72_08365	COG3856	small basic protein
RP72_08370	COG0849	cell division
RP72_08375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RP72_08380	COG1404	Belongs to the peptidase S8 family
RP72_08380	COG4412	M6 family metalloprotease domain protein
RP72_08390	COG1191	sigma factor activity
RP72_08395	COG1191	sigma factor activity
RP72_08400	COG1119	ATPase activity
RP72_08405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RP72_08410	COG1873	PFAM PRC-barrel domain
RP72_08420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RP72_08425	COG1799	cell septum assembly
RP72_08430	COG0762	integral membrane protein
RP72_08435	COG2302	S4 RNA-binding domain
RP72_08440	COG3599	regulation of cell shape
RP72_08445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RP72_08450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RP72_08455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RP72_08460	COG0564	pseudouridine synthase activity
RP72_08465	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
RP72_08470	COG2233	PERMEase
RP72_08475	COG0540	Belongs to the ATCase OTCase family
RP72_08480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RP72_08485	COG0505	Belongs to the CarA family
RP72_08490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RP72_08495	COG0543	2 iron, 2 sulfur cluster binding
RP72_08500	COG0167	dihydroorotate dehydrogenase activity
RP72_08505	COG0284	orotidine-5'-phosphate decarboxylase activity
RP72_08510	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RP72_08520	COG0175	sulfate reduction
RP72_08525	COG0306	phosphate transporter
RP72_08530	COG2046	Belongs to the sulfate adenylyltransferase family
RP72_08535	COG0529	Catalyzes the synthesis of activated sulfate
RP72_08540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RP72_08545	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
RP72_08550	COG1648	precorrin-2 dehydrogenase activity
RP72_08560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RP72_08565	COG1561	YicC-like family, N-terminal region
RP72_08570	COG2052	Domain of unknown function (DUF370)
RP72_08575	COG0194	GDP metabolic process
RP72_08580	COG1758	RNA polymerase activity
RP72_08585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RP72_08590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RP72_08595	COG0242	peptide deformylase activity
RP72_08600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RP72_08605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RP72_08605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RP72_08610	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RP72_08615	COG0631	protein serine/threonine phosphatase activity
RP72_08620	COG2815	serine threonine protein kinase
RP72_08620	COG0515	serine threonine protein kinase
RP72_08625	COG1162	GTPase activity
RP72_08630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RP72_08635	COG1564	THIamine pyrophosphokinase
RP72_08645	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RP72_08650	COG1302	Protein conserved in bacteria
RP72_08655	COG1461	Dihydroxyacetone kinase
RP72_08660	COG1760	l-serine dehydratase
RP72_08665	COG1760	l-serine dehydratase
RP72_08670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RP72_08675	COG1349	DNA-binding transcription factor activity
RP72_08675	COG2050	protein possibly involved in aromatic compounds catabolism
RP72_08680	COG0416	fatty acid biosynthetic process
RP72_08685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RP72_08690	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_08695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RP72_08700	COG0571	ribonuclease III activity
RP72_08705	COG1196	nuclear chromosome segregation
RP72_08710	COG0552	protein localization to endoplasmic reticulum
RP72_08720	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
RP72_08725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RP72_08730	COG0228	four-way junction DNA binding
RP72_08735	COG1837	Belongs to the UPF0109 family
RP72_08745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RP72_08750	COG0336	Belongs to the RNA methyltransferase TrmD family
RP72_08755	COG0335	large ribosomal subunit rRNA binding
RP72_08760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RP72_08765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RP72_08775	COG2257	FlhB HrpN YscU SpaS Family
RP72_08780	COG0045	succinate-CoA ligase (ADP-forming) activity
RP72_08785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RP72_08790	COG0758	DNA mediated transformation
RP72_08795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RP72_08800	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RP72_08805	COG4974	Belongs to the 'phage' integrase family
RP72_08810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RP72_08815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RP72_08820	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RP72_08825	COG1815	bacterial-type flagellum-dependent cell motility
RP72_08830	COG1558	bacterial-type flagellum-dependent cell motility
RP72_08835	COG1677	Flagellar hook-basal body complex protein FliE
RP72_08840	COG1766	The M ring may be actively involved in energy transduction
RP72_08845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RP72_08850	COG1317	bacterial-type flagellum organization
RP72_08855	COG1157	protein secretion by the type III secretion system
RP72_08860	COG2882	bacterial-type flagellum organization
RP72_08865	COG3334	PFAM MgtE intracellular
RP72_08870	COG3144	bacterial-type flagellum assembly
RP72_08875	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RP72_08880	COG4786	Flagellar basal body rod
RP72_08885	COG1582	Flagellar protein (FlbD)
RP72_08890	COG1580	Controls the rotational direction of flagella during chemotaxis
RP72_08895	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RP72_08900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RP72_08900	COG1776	CheC inhibitor of MCP methylation
RP72_08905	COG2201	protein-glutamate methylesterase activity
RP72_08910	COG3190	flagellar
RP72_08915	COG1338	Plays a role in the flagellum-specific transport system
RP72_08920	COG1987	bacterial-type flagellum assembly
RP72_08925	COG1684	flagellar biosynthetic protein fliR
RP72_08930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RP72_08935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RP72_08940	COG1419	protein localization to endoplasmic reticulum
RP72_08945	COG0455	bacterial-type flagellum organization
RP72_08950	COG2201	protein-glutamate methylesterase activity
RP72_08955	COG2198	Histidine kinase
RP72_08955	COG0643	Histidine kinase
RP72_08960	COG0835	chemotaxis
RP72_08965	COG1776	CheC inhibitor of MCP methylation
RP72_08970	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RP72_08975	COG1191	sigma factor activity
RP72_08985	COG0052	Belongs to the universal ribosomal protein uS2 family
RP72_08990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RP72_08995	COG0528	UMP kinase activity
RP72_09000	COG0233	cytoplasmic translational termination
RP72_09005	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RP72_09010	COG4589	Belongs to the CDS family
RP72_09015	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RP72_09020	COG0750	zinc metalloprotease
RP72_09025	COG0442	prolyl-tRNA aminoacylation
RP72_09030	COG2176	DNA-directed DNA polymerase activity
RP72_09035	COG0779	Required for maturation of 30S ribosomal subunits
RP72_09040	COG0195	Participates in both transcription termination and antitermination
RP72_09045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RP72_09050	COG1358	cellular component organization or biogenesis
RP72_09055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RP72_09060	COG1550	Protein conserved in bacteria
RP72_09065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RP72_09070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RP72_09075	COG0196	riboflavin kinase activity
RP72_09080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RP72_09085	COG1185	polyribonucleotide nucleotidyltransferase activity
RP72_09090	COG0726	polysaccharide deacetylase
RP72_09095	COG0612	Peptidase, M16
RP72_09100	COG1873	PFAM PRC-barrel domain
RP72_09110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RP72_09115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RP72_09120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RP72_09125	COG0527	aspartate kinase activity
RP72_09130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RP72_09135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RP72_09140	COG0740	serine-type endopeptidase activity
RP72_09150	COG4980	gas vesicle protein
RP72_09150	COG1674	ftsk spoiiie
RP72_09155	COG2188	Transcriptional regulator
RP72_09160	COG2814	Major facilitator Superfamily
RP72_09165	COG0612	Peptidase, M16
RP72_09170	COG0612	Peptidase, M16
RP72_09175	COG0300	oxidoreductase activity
RP72_09190	COG1426	Protein conserved in bacteria
RP72_09195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RP72_09200	COG1058	Belongs to the CinA family
RP72_09200	COG1546	Belongs to the CinA family
RP72_09205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RP72_09210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RP72_09215	COG1418	mRNA catabolic process
RP72_09220	COG1692	metallophosphoesterase
RP72_09225	COG2359	stage V sporulation protein S
RP72_09230	COG1063	alcohol dehydrogenase
RP72_09235	COG0156	8-amino-7-oxononanoate synthase activity
RP72_09240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RP72_09245	COG4550	Control of competence regulator ComK, YlbF/YmcA
RP72_09255	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RP72_09260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RP72_09280	COG3226	Transcriptional regulator
RP72_09285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_09295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RP72_09300	COG3321	synthase
RP72_09305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RP72_09305	COG2070	2-Nitropropane dioxygenase
RP72_09310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RP72_09315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RP72_09320	COG3425	synthase
RP72_09325	COG1024	Enoyl-CoA hydratase
RP72_09330	COG1024	Enoyl-CoA hydratase
RP72_09335	COG0318	PFAM AMP-dependent synthetase and ligase
RP72_09335	COG0300	oxidoreductase activity
RP72_09335	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_09335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09335	COG3321	synthase
RP72_09340	COG4221	oxidoreductase activity
RP72_09340	COG3321	synthase
RP72_09340	COG0300	oxidoreductase activity
RP72_09340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RP72_09345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RP72_09345	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_09345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09345	COG3321	synthase
RP72_09345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RP72_09350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09350	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_09350	COG3321	synthase
RP72_09350	COG4221	oxidoreductase activity
RP72_09355	COG3321	synthase
RP72_09355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RP72_09355	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RP72_09355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RP72_09360	COG2124	cytochrome p450
RP72_09370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_09375	COG1404	Belongs to the peptidase S8 family
RP72_09385	COG4195	phage-related replication protein
RP72_09390	COG1764	response to oxidative stress
RP72_09395	COG2076	Multidrug Resistance protein
RP72_09400	COG2076	Multidrug Resistance protein
RP72_09415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RP72_09420	COG1923	regulation of RNA biosynthetic process
RP72_09435	COG1780	Probably involved in ribonucleotide reductase function
RP72_09440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RP72_09445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RP72_09450	COG4112	unkown
RP72_09455	COG0860	N-Acetylmuramoyl-L-alanine amidase
RP72_09460	COG0464	growth
RP72_09470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RP72_09475	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RP72_09480	COG0789	Transcriptional regulator
RP72_09485	COG0174	glutamine synthetase
RP72_09505	COG4282	regulation of fungal-type cell wall biogenesis
RP72_09515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_09540	COG0135	phosphoribosylanthranilate isomerase activity
RP72_09545	COG2211	Major facilitator Superfamily
RP72_09550	COG3507	Belongs to the glycosyl hydrolase 43 family
RP72_09555	COG1940	carbohydrate kinase activity
RP72_09560	COG2115	Belongs to the xylose isomerase family
RP72_09565	COG1070	Carbohydrate kinase
RP72_09570	COG1525	nuclease
RP72_09575	COG2814	Major facilitator Superfamily
RP72_09580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RP72_09590	COG0756	dUTP diphosphatase activity
RP72_09600	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RP72_09625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RP72_09640	COG3832	glyoxalase III activity
RP72_09655	COG0697	spore germination
RP72_09660	COG0531	amino acid
RP72_09690	COG4195	phage-related replication protein
RP72_09700	COG0346	lactoylglutathione lyase activity
RP72_09710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RP72_09715	COG1388	LysM domain
RP72_09720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RP72_09725	COG4224	UPF0291 protein
RP72_09730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RP72_09740	COG3763	UPF0154 protein
RP72_09750	COG0785	Cytochrome C biogenesis protein
RP72_09755	COG2201	protein-glutamate methylesterase activity
RP72_09760	COG4846	Membrane protein involved in cytochrome C biogenesis
RP72_09770	COG0071	Belongs to the small heat shock protein (HSP20) family
RP72_09785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RP72_09790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_09810	COG0824	Thioesterase
RP72_09820	COG4841	protein insertion into membrane
RP72_09825	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RP72_09830	COG1832	CoA-binding protein
RP72_09835	COG0187	DNA topoisomerase II activity
RP72_09840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RP72_09855	COG1115	amino acid carrier protein
RP72_09860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RP72_09870	COG5520	Belongs to the glycosyl hydrolase 30 family
RP72_09875	COG3507	Belongs to the glycosyl hydrolase 43 family
RP72_09885	COG2246	polysaccharide biosynthetic process
RP72_09890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RP72_09895	COG0586	Pfam SNARE associated Golgi protein
RP72_09900	COG2404	hydrolase activity, acting on ester bonds
RP72_09905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RP72_09910	COG1024	Enoyl-CoA hydratase
RP72_09915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RP72_09920	COG0511	ligase activity, forming carbon-carbon bonds
RP72_09925	COG0439	Biotin carboxylase
RP72_09930	COG0318	PFAM AMP-dependent synthetase and ligase
RP72_09935	COG1960	acyl-CoA dehydrogenase activity
RP72_09950	COG1649	PFAM Uncharacterised BCR, COG1649
RP72_09960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RP72_09960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_09985	COG2027	D-alanyl-D-alanine carboxypeptidase
RP72_09990	COG2017	converts alpha-aldose to the beta-anomer
RP72_09995	COG0534	Mate efflux family protein
RP72_10010	COG0582	viral genome integration into host DNA
RP72_10015	COG0166	Belongs to the GPI family
RP72_10020	COG0405	Gamma-glutamyltransferase
RP72_10025	COG0583	DNA-binding transcription factor activity
RP72_10030	COG0604	alcohol dehydrogenase
RP72_10035	COG0493	'glutamate synthase
RP72_10040	COG0067	glutamate synthase
RP72_10040	COG0069	glutamate synthase activity
RP72_10040	COG0070	glutamate synthase
RP72_10045	COG0583	DNA-binding transcription factor activity
RP72_10050	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RP72_10055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RP72_10065	COG0300	oxidoreductase activity
RP72_10070	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
RP72_10080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_10085	COG2814	Major facilitator Superfamily
RP72_10090	COG1070	Carbohydrate kinase
RP72_10095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RP72_10100	COG0243	molybdopterin cofactor binding
RP72_10125	COG0840	transmembrane signaling receptor activity
RP72_10125	COG5278	phosphoserine phosphatase activity
RP72_10130	COG2368	4-hydroxyphenylacetate
RP72_10135	COG4305	rare lipoprotein A
RP72_10140	COG3619	membrane
RP72_10145	COG3866	Pectate lyase
RP72_10150	COG2135	peptidase activity
RP72_10160	COG2140	Oxalate decarboxylase
RP72_10170	COG0456	acetyltransferase
RP72_10185	COG2720	vancomycin resistance protein
RP72_10195	COG3655	Transcriptional regulator
RP72_10200	COG3739	integral membrane protein
RP72_10205	COG0583	DNA-binding transcription factor activity
RP72_10210	COG0697	spore germination
RP72_10220	COG0693	protein deglycase activity
RP72_10225	COG2367	Beta-lactamase
RP72_10245	COG3848	Pyruvate phosphate dikinase
RP72_10245	COG0574	Belongs to the PEP-utilizing enzyme family
RP72_10250	COG0726	polysaccharide deacetylase
RP72_10255	COG2314	TM2 domain
RP72_10260	COG1396	sequence-specific DNA binding
RP72_10275	COG2135	peptidase activity
RP72_10280	COG1793	dna ligase
RP72_10310	COG0457	Tetratricopeptide repeat
RP72_10320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RP72_10325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RP72_10340	COG5290	Psort location Cytoplasmic, score
RP72_10360	COG5444	nuclease activity
RP72_10365	COG4282	regulation of fungal-type cell wall biogenesis
RP72_10370	COG1231	oxidoreductase activity
RP72_10375	COG5434	Belongs to the glycosyl hydrolase 28 family
RP72_10380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RP72_10385	COG2207	Transcriptional regulator
RP72_10385	COG0662	Cupin 2, conserved barrel domain protein
RP72_10390	COG0456	acetyltransferase
RP72_10395	COG1309	transcriptional regulator
RP72_10400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_10405	COG3708	Transcriptional regulator
RP72_10410	COG2378	regulation of single-species biofilm formation
RP72_10420	COG0640	Transcriptional regulator
RP72_10425	COG0741	lytic transglycosylase activity
RP72_10430	COG2322	membrane
RP72_10445	COG1619	proteins homologs of microcin C7 resistance protein MccF
RP72_10450	COG3239	Fatty acid desaturase
RP72_10455	COG4585	Histidine kinase
RP72_10460	COG2197	response regulator
RP72_10465	COG1388	LysM domain
RP72_10465	COG3584	3D domain protein
RP72_10470	COG0514	ATP-dependent DNA helicase (RecQ)
RP72_10480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RP72_10485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RP72_10500	COG0071	Belongs to the small heat shock protein (HSP20) family
RP72_10525	COG1012	belongs to the aldehyde dehydrogenase family
RP72_10530	COG1657	PFAM Prenyltransferase squalene oxidase
RP72_10535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RP72_10540	COG0733	neurotransmitter:sodium symporter activity
RP72_10545	COG0385	Bile acid
RP72_10550	COG0508	dehydrogenase complex catalyzes the overall conversion of
RP72_10555	COG0567	Dehydrogenase, E1 component
RP72_10560	COG4548	von Willebrand factor, type A
RP72_10565	COG0714	Associated with various cellular activities
RP72_10570	COG2032	superoxide dismutase activity
RP72_10575	COG1388	LysM domain
RP72_10575	COG0791	NLP P60 protein
RP72_10580	COG1819	glycosyl
RP72_10585	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RP72_10590	COG0534	Mate efflux family protein
RP72_10595	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_10600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RP72_10605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RP72_10615	COG2962	Rard protein
RP72_10630	COG2610	gluconate transmembrane transporter activity
RP72_10635	COG1942	4-Oxalocrotonate Tautomerase
RP72_10640	COG1733	regulation of RNA biosynthetic process
RP72_10645	COG0778	Nitroreductase
RP72_10650	COG0400	carboxylic ester hydrolase activity
RP72_10655	COG0346	lactoylglutathione lyase activity
RP72_10665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RP72_10670	COG3409	Peptidoglycan-binding domain 1 protein
RP72_10670	COG0793	Belongs to the peptidase S41A family
RP72_10675	COG2226	methyltransferase
RP72_10685	COG1876	peptidase activity
RP72_10690	COG0813	purine-nucleoside phosphorylase activity
RP72_10705	COG0671	phosphoesterase, PA-phosphatase related
RP72_10730	COG4479	Belongs to the UPF0346 family
RP72_10740	COG1509	lysine 2,3-aminomutase activity
RP72_10745	COG0456	acetyltransferase
RP72_10750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RP72_10755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RP72_10760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RP72_10765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RP72_10780	COG0456	acetyltransferase
RP72_10785	COG0463	Glycosyl transferase, family 2
RP72_10800	COG4641	Protein conserved in bacteria
RP72_10805	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
RP72_10810	COG1086	Polysaccharide biosynthesis protein
RP72_10820	COG3331	DNA recombination
RP72_10870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RP72_10905	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
RP72_10910	COG0756	dUTP diphosphatase activity
RP72_10915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_10950	COG1780	Probably involved in ribonucleotide reductase function
RP72_11040	COG0270	DNA (cytosine-5-)-methyltransferase activity
RP72_11050	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
RP72_11055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RP72_11080	COG3584	3D domain protein
RP72_11085	COG0587	DNA-directed DNA polymerase activity
RP72_11090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RP72_11095	COG0358	DNA primase activity
RP72_11100	COG0305	Participates in initiation and elongation during chromosome replication
RP72_11110	COG2887	Belongs to the helicase family. UvrD subfamily
RP72_11140	COG5434	Belongs to the glycosyl hydrolase 28 family
RP72_11140	COG3420	alginic acid biosynthetic process
RP72_11145	COG4195	phage-related replication protein
RP72_11160	COG2135	peptidase activity
RP72_11165	COG1793	dna ligase
RP72_11220	COG4474	Belongs to the UPF0398 family
RP72_11230	COG1388	LysM domain
RP72_11250	COG3645	SOS response
RP72_11250	COG3646	Phage regulatory protein
RP72_11305	COG3655	Transcriptional regulator
RP72_11320	COG0582	viral genome integration into host DNA
RP72_11395	COG3655	Transcriptional regulator
RP72_11430	COG1395	domain, Protein
RP72_11445	COG0776	regulation of translation
RP72_11475	COG4373	Mu-like prophage FluMu protein gp28
RP72_11575	COG0582	viral genome integration into host DNA
RP72_11605	COG0741	lytic transglycosylase activity
RP72_11605	COG0739	heme binding
RP72_11605	COG1196	nuclear chromosome segregation
RP72_11615	COG2433	Pfam Transposase IS66
RP72_11625	COG4632	Exopolysaccharide biosynthesis protein
RP72_11625	COG5434	Belongs to the glycosyl hydrolase 28 family
RP72_11640	COG5632	N-Acetylmuramoyl-L-alanine amidase
RP72_11655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RP72_11660	COG0463	Glycosyl transferase, family 2
RP72_11665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_11670	COG2274	protein secretion by the type I secretion system
RP72_11670	COG3271	cysteine-type peptidase activity
RP72_11685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RP72_11715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RP72_11730	COG5444	nuclease activity
RP72_11735	COG4282	regulation of fungal-type cell wall biogenesis
RP72_11745	COG1525	nuclease
RP72_11755	COG2746	aminoglycoside 3-N-acetyltransferase activity
RP72_11780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RP72_11785	COG1086	Polysaccharide biosynthesis protein
RP72_11790	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RP72_11795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RP72_11800	COG1846	Transcriptional regulator
RP72_11805	COG0534	Mate efflux family protein
RP72_11815	COG4698	Protein conserved in bacteria
RP72_11820	COG2755	lipolytic protein G-D-S-L family
RP72_11825	COG1999	signal sequence binding
RP72_11840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RP72_11845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RP72_11850	COG1272	protein, Hemolysin III
RP72_11855	COG0204	Acyl-transferase
RP72_11860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RP72_11865	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RP72_11870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RP72_11880	COG2521	methyltransferase
RP72_11880	COG2136	Putative SAM-dependent methyltransferase
RP72_11890	COG0129	dihydroxy-acid dehydratase activity
RP72_11895	COG1413	lyase activity
RP72_11900	COG1418	mRNA catabolic process
RP72_11905	COG0386	Belongs to the glutathione peroxidase family
RP72_11910	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RP72_11915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RP72_11920	COG1278	Cold shock
RP72_11940	COG0328	RNA-DNA hybrid ribonuclease activity
RP72_11945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RP72_11950	COG0328	RNA-DNA hybrid ribonuclease activity
RP72_11960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RP72_11980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RP72_11985	COG1755	Isoprenylcysteine carboxyl methyltransferase
RP72_11990	COG3424	synthase
RP72_11995	COG2233	PERMEase
RP72_12000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RP72_12005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
RP72_12015	COG0800	Aldolase
RP72_12020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RP72_12025	COG1609	Transcriptional regulator
RP72_12030	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
RP72_12035	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_12040	COG1199	ATP-dependent helicase activity
RP72_12050	COG0116	Belongs to the methyltransferase superfamily
RP72_12060	COG4474	Belongs to the UPF0398 family
RP72_12070	COG3359	exonuclease
RP72_12075	COG1111	helicase
RP72_12075	COG1205	dead DEAH box helicase
RP72_12080	COG2190	(PTS) system
RP72_12085	COG0071	Belongs to the small heat shock protein (HSP20) family
RP72_12120	COG3331	DNA recombination
RP72_12125	COG4499	WXG100 protein secretion system (Wss), protein YukC
RP72_12125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RP72_12135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RP72_12140	COG3935	DnaD domain protein
RP72_12145	COG0017	Asparaginyl-tRNA synthetase
RP72_12150	COG0436	Aminotransferase
RP72_12155	COG5353	protein conserved in bacteria
RP72_12165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RP72_12165	COG1199	ATP-dependent helicase activity
RP72_12170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RP72_12175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RP72_12180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RP72_12185	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RP72_12185	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RP72_12190	COG0617	tRNA 3'-terminal CCA addition
RP72_12195	COG0438	transferase activity, transferring glycosyl groups
RP72_12200	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RP72_12205	COG1803	Methylglyoxal synthase
RP72_12210	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RP72_12215	COG1694	Mazg nucleotide pyrophosphohydrolase
RP72_12220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RP72_12230	COG4347	Protein of unknown function (DUF1405)
RP72_12235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RP72_12235	COG2010	Cytochrome c
RP72_12240	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RP72_12245	COG0723	plastoquinol--plastocyanin reductase activity
RP72_12255	COG5582	Belongs to the UPF0302 family
RP72_12260	COG0457	Tetratricopeptide repeat
RP72_12265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RP72_12270	COG0287	Prephenate dehydrogenase
RP72_12275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RP72_12280	COG0159	tryptophan synthase activity
RP72_12285	COG0133	tryptophan synthase activity
RP72_12290	COG0135	phosphoribosylanthranilate isomerase activity
RP72_12300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RP72_12305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RP72_12310	COG4401	Chorismate mutase type I
RP72_12315	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RP72_12320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RP72_12325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RP72_12335	COG0105	UTP biosynthetic process
RP72_12340	COG0142	geranyltranstransferase activity
RP72_12345	COG2226	methyltransferase
RP72_12350	COG0142	geranyltranstransferase activity
RP72_12360	COG0302	gtp cyclohydrolase
RP72_12365	COG0776	regulation of translation
RP72_12370	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RP72_12385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RP72_12390	COG1160	GTP binding
RP72_12415	COG1304	FMN binding
RP72_12420	COG0539	negative regulation of cytoplasmic translation
RP72_12425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RP72_12435	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RP72_12440	COG2959	enzyme of heme biosynthesis
RP72_12445	COG3773	Cell wall hydrolase
RP72_12445	COG3409	Peptidoglycan-binding domain 1 protein
RP72_12450	COG2339	peptidase activity
RP72_12455	COG0492	ferredoxin-NADP+ reductase activity
RP72_12460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RP72_12465	COG4862	establishment of competence for transformation
RP72_12470	COG1408	metallophosphoesterase
RP72_12480	COG1388	LysM domain
RP72_12485	COG1266	CAAX protease self-immunity
RP72_12490	COG0514	ATP-dependent DNA helicase (RecQ)
RP72_12495	COG4955	Helix-turn-helix domain
RP72_12500	COG1141	Ferredoxin
RP72_12505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
RP72_12515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RP72_12520	COG0710	3-dehydroquinate dehydratase activity
RP72_12530	COG1595	DNA-templated transcription, initiation
RP72_12535	COG5002	protein histidine kinase activity
RP72_12540	COG0745	RESPONSE REGULATOR receiver
RP72_12545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RP72_12550	COG1333	cytochrome c biogenesis protein
RP72_12555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_12560	COG1187	pseudouridine synthase activity
RP72_12565	COG0700	Nucleoside recognition
RP72_12570	COG2715	membrane protein required for spore maturation
RP72_12575	COG1686	Belongs to the peptidase S11 family
RP72_12585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RP72_12590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RP72_12595	COG1547	Domain of unknown function (DUF309)
RP72_12600	COG0456	acetyltransferase
RP72_12605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RP72_12610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RP72_12610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RP72_12615	COG0307	riboflavin synthase, alpha
RP72_12620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RP72_12620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RP72_12630	COG0681	Belongs to the peptidase S26 family
RP72_12635	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
RP72_12660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RP72_12665	COG4086	secreted protein
RP72_12670	COG0019	diaminopimelate decarboxylase activity
RP72_12675	COG0697	spore germination
RP72_12690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RP72_12710	COG1191	sigma factor activity
RP72_12715	COG2172	sigma factor antagonist activity
RP72_12720	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_12725	COG1686	Belongs to the peptidase S11 family
RP72_12730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RP72_12735	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RP72_12740	COG4974	Belongs to the 'phage' integrase family
RP72_12750	COG0735	belongs to the Fur family
RP72_12755	COG1300	Membrane
RP72_12765	COG0281	malic enzyme
RP72_12770	COG1757	Na H antiporter
RP72_12775	COG1027	Aspartate ammonia-lyase
RP72_12780	COG0252	asparaginase activity
RP72_12785	COG1396	sequence-specific DNA binding
RP72_12790	COG1379	DNA repair
RP72_12795	COG0494	nUDIX hydrolase
RP72_12805	COG0667	Aldo Keto reductase
RP72_12815	COG1073	alpha beta
RP72_12825	COG4918	Iron-sulphur cluster biosynthesis
RP72_12830	COG0456	acetyltransferase
RP72_12830	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RP72_12835	COG2329	Antibiotic biosynthesis monooxygenase
RP72_12840	COG0456	acetyltransferase
RP72_12850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RP72_12860	COG2211	Major facilitator Superfamily
RP72_12870	COG0346	lactoylglutathione lyase activity
RP72_12875	COG1072	(Pantothenic acid kinase))
RP72_12880	COG3048	D-serine ammonia-lyase activity
RP72_12885	COG0300	oxidoreductase activity
RP72_12890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_12895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RP72_12900	COG4187	Peptidase family M20/M25/M40
RP72_12905	COG1902	pentaerythritol trinitrate reductase activity
RP72_12910	COG0596	Alpha beta hydrolase
RP72_12915	COG1234	tRNA 3'-trailer cleavage
RP72_12920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RP72_12925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RP72_12930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RP72_12940	COG0706	membrane insertase activity
RP72_12945	COG3361	conserved protein (COG2071)
RP72_12950	COG2195	Cleaves the N-terminal amino acid of tripeptides
RP72_12955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RP72_12960	COG0346	lactoylglutathione lyase activity
RP72_12970	COG1376	ErfK ybiS ycfS ynhG family protein
RP72_12975	COG4129	membrane
RP72_12980	COG1126	abc transporter atp-binding protein
RP72_12985	COG0765	amino acid transport
RP72_12990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RP72_13000	COG1597	lipid kinase activity
RP72_13005	COG2814	Major facilitator Superfamily
RP72_13010	COG4978	Transcriptional regulator
RP72_13010	COG0789	Transcriptional regulator
RP72_13015	COG0508	dehydrogenase complex catalyzes the overall conversion of
RP72_13020	COG0022	dehydrogenase e1 component
RP72_13025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RP72_13030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RP72_13035	COG3426	butyrate kinase activity
RP72_13040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RP72_13045	COG0280	phosphate acetyltransferase
RP72_13050	COG3290	protein histidine kinase activity
RP72_13050	COG3829	transcription factor binding
RP72_13060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RP72_13065	COG2079	MmgE PrpD family protein
RP72_13070	COG0372	Belongs to the citrate synthase family
RP72_13075	COG1960	acyl-CoA dehydrogenase activity
RP72_13080	COG1250	3-hydroxyacyl-CoA dehydrogenase
RP72_13085	COG0183	Belongs to the thiolase family
RP72_13090	COG0584	glycerophosphoryl diester phosphodiesterase
RP72_13095	COG0860	N-Acetylmuramoyl-L-alanine amidase
RP72_13110	COG1902	pentaerythritol trinitrate reductase activity
RP72_13130	COG0750	zinc metalloprotease
RP72_13135	COG0497	DNA recombination
RP72_13140	COG1438	arginine binding
RP72_13145	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RP72_13150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RP72_13155	COG0142	geranyltranstransferase activity
RP72_13160	COG1722	exodeoxyribonuclease VII activity
RP72_13165	COG1570	exodeoxyribonuclease VII activity
RP72_13170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RP72_13175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RP72_13180	COG1302	Protein conserved in bacteria
RP72_13185	COG0439	Biotin carboxylase
RP72_13190	COG0511	ligase activity, forming carbon-carbon bonds
RP72_13230	COG3854	ATPases associated with a variety of cellular activities
RP72_13240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RP72_13245	COG0006	proline dipeptidase activity
RP72_13250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RP72_13260	COG3872	metal-dependent enzyme
RP72_13270	COG1752	Esterase of the alpha-beta hydrolase superfamily
RP72_13275	COG1321	iron dependent repressor
RP72_13280	COG0095	Lipoate-protein ligase
RP72_13285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RP72_13290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RP72_13295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RP72_13300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RP72_13305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RP72_13320	COG1396	sequence-specific DNA binding
RP72_13330	COG0681	Belongs to the peptidase S26 family
RP72_13355	COG4940	Competence protein ComGF
RP72_13365	COG4970	Tfp pilus assembly protein FimT
RP72_13370	COG4537	Required for transformation and DNA binding
RP72_13375	COG1459	type II secretion system
RP72_13380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RP72_13390	COG0598	Magnesium transport protein CorA
RP72_13395	COG1253	flavin adenine dinucleotide binding
RP72_13400	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_13410	COG1393	Belongs to the ArsC family
RP72_13420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_13430	COG0011	TIGRFAM Protein of
RP72_13440	COG2866	Carboxypeptidase
RP72_13445	COG1368	sulfuric ester hydrolase activity
RP72_13450	COG1940	carbohydrate kinase activity
RP72_13455	COG4483	Protein conserved in bacteria
RP72_13460	COG0705	Rhomboid family
RP72_13460	COG0457	Tetratricopeptide repeat
RP72_13470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RP72_13475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RP72_13480	COG0438	transferase activity, transferring glycosyl groups
RP72_13495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RP72_13500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RP72_13505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RP72_13510	COG0581	inorganic phosphate transmembrane transporter activity
RP72_13515	COG0573	inorganic phosphate transmembrane transporter activity
RP72_13520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RP72_13530	COG0477	Major facilitator Superfamily
RP72_13535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RP72_13540	COG2839	Protein conserved in bacteria
RP72_13545	COG5521	maltodextrose utilization protein MalA
RP72_13555	COG1388	LysM domain
RP72_13560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RP72_13565	COG4709	membrane
RP72_13570	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
RP72_13575	COG0735	belongs to the Fur family
RP72_13580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RP72_13590	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
RP72_13595	COG0513	Belongs to the DEAD box helicase family
RP72_13605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RP72_13610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RP72_13615	COG2384	SAM-dependent methyltransferase
RP72_13620	COG2010	Cytochrome c
RP72_13625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RP72_13630	COG0358	DNA primase activity
RP72_13635	COG1671	Belongs to the UPF0178 family
RP72_13640	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RP72_13645	COG0517	IMP dehydrogenase activity
RP72_13650	COG0751	glycine-tRNA ligase activity
RP72_13655	COG0752	glycyl-tRNA synthetase alpha subunit
RP72_13660	COG1381	Involved in DNA repair and RecF pathway recombination
RP72_13670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RP72_13675	COG0295	cytidine deaminase activity
RP72_13680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RP72_13685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RP72_13690	COG1480	7TM receptor with intracellular HD hydrolase
RP72_13700	COG1702	phosphate starvation-inducible protein PhoH
RP72_13705	COG0561	phosphatase activity
RP72_13720	COG4864	UPF0365 protein
RP72_13725	COG1030	water channel activity
RP72_13730	COG1610	YqeY-like protein
RP72_13735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RP72_13740	COG1283	sodium-dependent phosphate transmembrane transporter activity
RP72_13745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RP72_13750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RP72_13755	COG2264	protein methyltransferase activity
RP72_13760	COG0484	heat shock protein binding
RP72_13765	COG0443	Heat shock 70 kDa protein
RP72_13770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RP72_13775	COG1420	regulation of RNA biosynthetic process
RP72_13780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RP72_13785	COG0481	GTPase activity
RP72_13795	COG0860	N-Acetylmuramoyl-L-alanine amidase
RP72_13800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RP72_13805	COG0268	Binds directly to 16S ribosomal RNA
RP72_13810	COG1466	dna polymerase III delta subunit
RP72_13820	COG0658	competence protein
RP72_13820	COG2333	competence protein COMEC
RP72_13825	COG2131	deaminase
RP72_13830	COG1555	photosystem II stabilization
RP72_13830	COG1596	polysaccharide export
RP72_13835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RP72_13840	COG2226	methyltransferase
RP72_13845	COG0799	negative regulation of ribosome biogenesis
RP72_13850	COG1713	HD superfamily hydrolase involved in NAD metabolism
RP72_13855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RP72_13860	COG1534	Rna-binding protein
RP72_13865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RP72_13870	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RP72_13875	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RP72_13890	COG2755	lipolytic protein G-D-S-L family
RP72_13895	COG3409	Peptidoglycan-binding domain 1 protein
RP72_13895	COG5632	N-Acetylmuramoyl-L-alanine amidase
RP72_13900	COG0398	Pfam SNARE associated Golgi protein
RP72_13905	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RP72_13915	COG3209	COG3209 Rhs family protein
RP72_13925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RP72_13930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RP72_13935	COG0798	PFAM Bile acid sodium symporter
RP72_13940	COG0346	lactoylglutathione lyase activity
RP72_13945	COG0640	Transcriptional regulator
RP72_13950	COG3403	YqcI/YcgG family
RP72_13955	COG0457	Tetratricopeptide repeat
RP72_13970	COG5444	nuclease activity
RP72_13995	COG3409	Peptidoglycan-binding domain 1 protein
RP72_13995	COG5632	N-Acetylmuramoyl-L-alanine amidase
RP72_14000	COG4824	toxin secretion phage lysis holin
RP72_14030	COG3778	Protein conserved in bacteria
RP72_14035	COG3299	homolog of phage Mu protein gp47
RP72_14040	COG3628	GPW Gp25 family protein
RP72_14050	COG4193	domain, Protein
RP72_14055	COG1652	LysM domain
RP72_14060	COG3953	SLT domain
RP72_14060	COG5280	Phage tail tape measure protein TP901
RP72_14120	COG4653	Phage capsid family
RP72_14125	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RP72_14135	COG2369	cell adhesion
RP72_14140	COG5518	Phage portal protein
RP72_14145	COG1783	phage Terminase large subunit
RP72_14150	COG5484	DNA packaging
RP72_14160	COG3677	Transposase
RP72_14175	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
RP72_14190	COG1484	DNA-dependent DNA replication
RP72_14195	COG3935	DnaD domain protein
RP72_14200	COG3723	Recombinational DNA repair protein, rece pathway
RP72_14205	COG5377	YqaJ viral recombinase family
RP72_14230	COG1476	TRANSCRIPTIONal
RP72_14235	COG3620	sequence-specific DNA binding
RP72_14245	COG0563	adenylate kinase activity
RP72_14250	COG2856	Zn peptidase
RP72_14265	COG3223	Belongs to the PsiE family
RP72_14270	COG0642	Histidine kinase
RP72_14270	COG5002	protein histidine kinase activity
RP72_14275	COG0745	RESPONSE REGULATOR receiver
RP72_14280	COG2311	Membrane
RP72_14290	COG0454	-acetyltransferase
RP72_14295	COG2249	NAD(P)H dehydrogenase (quinone) activity
RP72_14305	COG0730	response to heat
RP72_14310	COG0425	Belongs to the sulfur carrier protein TusA family
RP72_14315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RP72_14315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_14325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RP72_14325	COG0425	Belongs to the sulfur carrier protein TusA family
RP72_14330	COG2210	Belongs to the sulfur carrier protein TusA family
RP72_14335	COG1937	Protein conserved in bacteria
RP72_14340	COG0662	Cupin 2, conserved barrel domain protein
RP72_14355	COG0789	Transcriptional regulator
RP72_14355	COG4978	Transcriptional regulator
RP72_14360	COG2814	Major facilitator Superfamily
RP72_14365	COG0456	acetyltransferase
RP72_14370	COG1253	flavin adenine dinucleotide binding
RP72_14380	COG0697	spore germination
RP72_14385	COG0583	DNA-binding transcription factor activity
RP72_14390	COG2072	flavoprotein involved in K transport
RP72_14395	COG1230	cation diffusion facilitator family transporter
RP72_14400	COG1942	4-Oxalocrotonate Tautomerase
RP72_14405	COG0583	DNA-binding transcription factor activity
RP72_14415	COG1114	Component of the transport system for branched-chain amino acids
RP72_14420	COG1687	branched-chain amino acid
RP72_14425	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
RP72_14430	COG1522	sequence-specific DNA binding
RP72_14435	COG2732	(Barnase) inhibitor
RP72_14440	COG2124	cytochrome p450
RP72_14450	COG1335	isochorismatase
RP72_14460	COG2318	DinB family
RP72_14470	COG2070	2-Nitropropane dioxygenase
RP72_14475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RP72_14490	COG3443	Belongs to the bacterial solute-binding protein 9 family
RP72_14495	COG1595	DNA-templated transcription, initiation
RP72_14500	COG0667	Aldo Keto reductase
RP72_14505	COG2851	Citrate transporter
RP72_14510	COG0583	DNA-binding transcription factor activity
RP72_14515	COG2828	Protein conserved in bacteria
RP72_14520	COG3409	Peptidoglycan-binding domain 1 protein
RP72_14525	COG5566	PFAM Mor transcription activator
RP72_14530	COG0596	Alpha beta hydrolase
RP72_14535	COG4991	sh3 domain protein
RP72_14540	COG4991	sh3 domain protein
RP72_14545	COG0346	lactoylglutathione lyase activity
RP72_14555	COG5577	PFAM Coat F domain
RP72_14560	COG1063	alcohol dehydrogenase
RP72_14570	COG5577	PFAM Coat F domain
RP72_14575	COG0789	Transcriptional regulator
RP72_14585	COG1064	alcohol dehydrogenase
RP72_14590	COG0693	protein deglycase activity
RP72_14595	COG1621	beta-fructofuranosidase activity
RP72_14600	COG3716	PTS system mannose fructose sorbose family IID component
RP72_14605	COG3715	PTS system
RP72_14610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_14615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_14620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RP72_14620	COG3933	PFAM sigma-54 factor interaction domain-containing protein
RP72_14625	COG1113	amino acid transport
RP72_14630	COG1280	lysine exporter protein (LysE YggA)
RP72_14635	COG1378	Sugar-specific transcriptional regulator TrmB
RP72_14640	COG1595	DNA-templated transcription, initiation
RP72_14650	COG2755	lipolytic protein G-D-S-L family
RP72_14650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RP72_14660	COG2124	cytochrome p450
RP72_14660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RP72_14665	COG1309	transcriptional regulator
RP72_14670	COG2226	methyltransferase
RP72_14680	COG2116	formate transmembrane transporter activity
RP72_14685	COG5609	conserved protein (DUF2294)
RP72_14690	COG3383	formate dehydrogenase (NAD+) activity
RP72_14695	COG2427	Protein of unknown function (DUF1641)
RP72_14705	COG0626	cystathionine gamma-synthase activity
RP72_14710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RP72_14715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RP72_14720	COG2226	methyltransferase
RP72_14735	COG0768	penicillin binding
RP72_14740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RP72_14745	COG0572	uridine kinase
RP72_14765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RP72_14770	COG3906	Belongs to the UPF0473 family
RP72_14775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RP72_14780	COG4472	Bacterial protein of unknown function (DUF965)
RP72_14785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RP72_14790	COG0628	permease
RP72_14795	COG1126	abc transporter atp-binding protein
RP72_14800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RP72_14805	COG0765	amino acid transport
RP72_14810	COG0765	amino acid transport
RP72_14825	COG3881	PFAM PRC-barrel domain
RP72_14830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RP72_14835	COG0457	Tetratricopeptide repeat
RP72_14840	COG0482	sulfurtransferase activity
RP72_14845	COG1104	cysteine desulfurase activity
RP72_14850	COG1959	2 iron, 2 sulfur cluster binding
RP72_14855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RP72_14860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RP72_14870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RP72_14875	COG0124	histidyl-tRNA synthetase
RP72_14885	COG0860	N-Acetylmuramoyl-L-alanine amidase
RP72_14885	COG4991	sh3 domain protein
RP72_14885	COG3103	Sh3 type 3 domain protein
RP72_14890	COG1490	D-aminoacyl-tRNA deacylase activity
RP72_14895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RP72_14900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RP72_14905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RP72_14905	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RP72_14910	COG5416	Lipopolysaccharide assembly protein A domain
RP72_14915	COG0490	domain, Protein
RP72_14920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RP72_14920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RP72_14930	COG2244	polysaccharide biosynthetic process
RP72_14935	COG2323	membrane
RP72_14945	COG1862	Preprotein translocase
RP72_14950	COG0343	queuine tRNA-ribosyltransferase activity
RP72_14955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RP72_14965	COG2255	four-way junction helicase activity
RP72_14970	COG0632	four-way junction helicase activity
RP72_14980	COG2814	Major facilitator Superfamily
RP72_14985	COG0673	inositol 2-dehydrogenase activity
RP72_14990	COG2112	serine threonine protein kinase
RP72_15010	COG1115	amino acid carrier protein
RP72_15015	COG0217	transcriptional regulatory protein
RP72_15025	COG1388	LysM domain
RP72_15030	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RP72_15035	COG0157	Belongs to the NadC ModD family
RP72_15040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RP72_15045	COG1104	cysteine desulfurase activity
RP72_15050	COG1827	regulation of RNA biosynthetic process
RP72_15055	COG0077	Prephenate dehydratase
RP72_15060	COG4492	Belongs to the UPF0735 family
RP72_15065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RP72_15070	COG3290	protein histidine kinase activity
RP72_15080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RP72_15085	COG2868	ribosomal protein
RP72_15090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RP72_15095	COG1994	Peptidase M50
RP72_15100	COG0739	heme binding
RP72_15105	COG2894	cell division
RP72_15110	COG0850	regulation of cytokinetic process
RP72_15115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RP72_15120	COG1792	Involved in formation and maintenance of cell shape
RP72_15125	COG1077	Cell shape determining protein MreB Mrl
RP72_15130	COG2003	Belongs to the UPF0758 family
RP72_15135	COG0424	maF-like protein
RP72_15145	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RP72_15150	COG0285	dihydrofolate synthase activity
RP72_15155	COG0525	valine-tRNA ligase activity
RP72_15165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RP72_15170	COG1388	LysM domain
RP72_15175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RP72_15180	COG0113	porphobilinogen synthase activity
RP72_15185	COG1587	Uroporphyrinogen-III synthase
RP72_15190	COG0181	hydroxymethylbilane synthase activity
RP72_15195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RP72_15200	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RP72_15210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RP72_15215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RP72_15220	COG0470	DNA polymerase III
RP72_15220	COG1067	ATP-dependent peptidase activity
RP72_15225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RP72_15230	COG0544	peptidyl-prolyl cis-trans isomerase activity
RP72_15235	COG0457	Tetratricopeptide repeat
RP72_15235	COG1477	protein flavinylation
RP72_15240	COG0066	3-isopropylmalate dehydratase activity
RP72_15245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RP72_15250	COG0473	3-isopropylmalate dehydrogenase activity
RP72_15255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RP72_15260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RP72_15265	COG0440	acetolactate synthase activity
RP72_15270	COG0028	Belongs to the TPP enzyme family
RP72_15280	COG0454	-acetyltransferase
RP72_15290	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
RP72_15300	COG0622	Phosphoesterase
RP72_15305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RP72_15310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RP72_15315	COG5401	PFAM Sporulation and spore germination
RP72_15320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RP72_15325	COG1846	Transcriptional regulator
RP72_15330	COG2197	response regulator
RP72_15335	COG0824	Thioesterase
RP72_15340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RP72_15345	COG1053	succinate dehydrogenase
RP72_15350	COG2009	succinate dehydrogenase
RP72_15360	COG1719	4-vinyl reductase, 4VR
RP72_15365	COG0527	aspartate kinase activity
RP72_15370	COG0322	excinuclease ABC activity
RP72_15375	COG3118	belongs to the thioredoxin family
RP72_15380	COG3534	alpha-L-arabinofuranosidase
RP72_15385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RP72_15390	COG2086	electron transfer activity
RP72_15395	COG1024	Enoyl-CoA hydratase
RP72_15400	COG1309	transcriptional regulator
RP72_15405	COG0318	PFAM AMP-dependent synthetase and ligase
RP72_15410	COG3766	membrane
RP72_15415	COG1193	negative regulation of DNA recombination
RP72_15420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RP72_15420	COG1796	DNA polymerase
RP72_15425	COG1286	toxin biosynthetic process
RP72_15430	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RP72_15435	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RP72_15440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RP72_15440	COG0072	phenylalanine-tRNA ligase activity
RP72_15445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RP72_15455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RP72_15465	COG3835	regulator
RP72_15470	COG0277	FAD linked oxidase domain protein
RP72_15475	COG0247	lactate metabolic process
RP72_15480	COG0346	lactoylglutathione lyase activity
RP72_15490	COG1966	Carbon starvation protein
RP72_15495	COG3534	alpha-L-arabinofuranosidase
RP72_15500	COG0395	ABC-type sugar transport system, permease component
RP72_15505	COG1175	transmembrane transport
RP72_15510	COG1653	transport
RP72_15515	COG0371	Dehydrogenase
RP72_15520	COG0647	UMP catabolic process
RP72_15525	COG0235	Class ii aldolase
RP72_15530	COG1069	ribulokinase activity
RP72_15535	COG2160	L-arabinose isomerase activity
RP72_15540	COG3507	Belongs to the glycosyl hydrolase 43 family
RP72_15545	COG1363	Peptidase, m42
RP72_15555	COG3326	Membrane
RP72_15560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RP72_15565	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RP72_15570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RP72_15580	COG1346	cytolysis
RP72_15585	COG1380	Effector of murein hydrolase LrgA
RP72_15590	COG3279	Response regulator of the LytR AlgR family
RP72_15595	COG3275	phosphorelay sensor kinase activity
RP72_15605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RP72_15615	COG0398	Pfam SNARE associated Golgi protein
RP72_15620	COG1484	DNA-dependent DNA replication
RP72_15625	COG3611	Membrane attachment protein
RP72_15630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RP72_15635	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RP72_15640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RP72_15645	COG1733	regulation of RNA biosynthetic process
RP72_15650	COG2814	Major facilitator Superfamily
RP72_15655	COG0656	L-ascorbic acid biosynthetic process
RP72_15660	COG0237	dephospho-CoA kinase activity
RP72_15675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RP72_15680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RP72_15680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RP72_15685	COG5002	protein histidine kinase activity
RP72_15690	COG0745	RESPONSE REGULATOR receiver
RP72_15695	COG0039	L-malate dehydrogenase activity
RP72_15700	COG0538	isocitrate dehydrogenase activity
RP72_15705	COG0372	Belongs to the citrate synthase family
RP72_15710	COG2707	UPF0756 membrane protein
RP72_15715	COG0628	permease
RP72_15720	COG3030	protein affecting phage T7 exclusion by the F plasmid
RP72_15725	COG0469	pyruvate kinase activity
RP72_15730	COG0205	6-phosphofructokinase activity
RP72_15735	COG0825	malonyl-CoA metabolic process
RP72_15740	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RP72_15745	COG0281	malic enzyme
RP72_15750	COG0587	DNA-directed DNA polymerase activity
RP72_15770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RP72_15780	COG4109	DRTGG domain
RP72_15790	COG0730	response to heat
RP72_15795	COG1473	amidohydrolase
RP72_15800	COG0196	riboflavin kinase activity
RP72_15805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RP72_15810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RP72_15815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RP72_15820	COG1126	abc transporter atp-binding protein
RP72_15825	COG0765	amino acid transport
RP72_15830	COG0765	amino acid transport
RP72_15835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RP72_15840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RP72_15845	COG0454	-acetyltransferase
RP72_15850	COG0583	DNA-binding transcription factor activity
RP72_15855	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RP72_15860	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_15870	COG0165	Argininosuccinate lyase
RP72_15875	COG0137	argininosuccinate synthase activity
RP72_15880	COG0521	Mo-molybdopterin cofactor biosynthetic process
RP72_15885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RP72_15890	COG0827	DNA restriction-modification system
RP72_15895	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RP72_15900	COG3874	Sporulation protein YtfJ
RP72_15910	COG1714	RDD family
RP72_15915	COG0616	signal peptide processing
RP72_15920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RP72_15925	COG1574	metal-dependent hydrolase with the TIM-barrel fold
RP72_15930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RP72_15940	COG0301	tRNA thio-modification
RP72_15945	COG1104	cysteine desulfurase activity
RP72_15950	COG1114	Component of the transport system for branched-chain amino acids
RP72_15955	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
RP72_15960	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RP72_15965	COG1309	transcriptional regulator
RP72_15970	COG1956	GAF domain-containing protein
RP72_15975	COG2199	diguanylate cyclase activity
RP72_15975	COG2203	Gaf domain
RP72_15980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RP72_15990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RP72_15995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RP72_16000	COG0454	-acetyltransferase
RP72_16005	COG0517	IMP dehydrogenase activity
RP72_16010	COG0123	including yeast histone deacetylase and acetoin utilization protein
RP72_16015	COG1360	Flagellar Motor Protein
RP72_16020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RP72_16025	COG1609	Transcriptional regulator
RP72_16030	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RP72_16030	COG1605	Chorismate mutase
RP72_16035	COG3118	belongs to the thioredoxin family
RP72_16040	COG4980	gas vesicle protein
RP72_16045	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
RP72_16050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RP72_16055	COG1674	ftsk spoiiie
RP72_16060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RP72_16065	COG4848	Belongs to the UPF0354 family
RP72_16070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_16080	COG1363	Peptidase, m42
RP72_16085	COG5584	Small secreted protein
RP72_16090	COG0281	malic enzyme
RP72_16095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_16100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RP72_16110	COG0510	thiamine kinase activity
RP72_16115	COG1523	belongs to the glycosyl hydrolase 13 family
RP72_16120	COG1597	lipid kinase activity
RP72_16130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RP72_16135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RP72_16140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RP72_16145	COG2252	PERMEase
RP72_16150	COG4473	ABC transporter
RP72_16155	COG1131	(ABC) transporter
RP72_16160	COG1349	DNA-binding transcription factor activity
RP72_16165	COG1187	pseudouridine synthase activity
RP72_16170	COG2244	polysaccharide biosynthetic process
RP72_16175	COG2081	HI0933 family
RP72_16180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RP72_16190	COG5578	integral membrane protein
RP72_16195	COG0673	inositol 2-dehydrogenase activity
RP72_16200	COG1653	transport
RP72_16205	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RP72_16210	COG4209	transmembrane transport
RP72_16215	COG2207	Transcriptional regulator
RP72_16220	COG1653	transport
RP72_16225	COG0395	ABC-type sugar transport system, permease component
RP72_16230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RP72_16235	COG2124	cytochrome p450
RP72_16240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RP72_16245	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RP72_16250	COG0156	8-amino-7-oxononanoate synthase activity
RP72_16255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RP72_16260	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
RP72_16265	COG1073	alpha beta
RP72_16290	COG1486	melibiose metabolic process
RP72_16295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RP72_16300	COG0495	leucyl-tRNA aminoacylation
RP72_16310	COG2202	Pas domain
RP72_16310	COG1366	Belongs to the anti-sigma-factor antagonist family
RP72_16315	COG2814	Major facilitator Superfamily
RP72_16320	COG2433	Pfam Transposase IS66
RP72_16325	COG0577	efflux transmembrane transporter activity
RP72_16330	COG1136	(ABC) transporter
RP72_16335	COG2205	protein histidine kinase activity
RP72_16340	COG0745	RESPONSE REGULATOR receiver
RP72_16345	COG0577	efflux transmembrane transporter activity
RP72_16350	COG1136	(ABC) transporter
RP72_16365	COG1131	(ABC) transporter
RP72_16370	COG1725	Transcriptional regulator
RP72_16385	COG1242	4 iron, 4 sulfur cluster binding
RP72_16390	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RP72_16400	COG2267	carboxylic ester hydrolase activity
RP72_16405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RP72_16410	COG1113	amino acid transport
RP72_16415	COG0367	asparagine synthase
RP72_16420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RP72_16425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RP72_16435	COG1506	peptidase
RP72_16440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RP72_16445	COG1116	anion transmembrane transporter activity
RP72_16450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RP72_16455	COG0494	nUDIX hydrolase
RP72_16460	COG4824	toxin secretion phage lysis holin
RP72_16465	COG0783	Belongs to the Dps family
RP72_16480	COG1854	S-ribosylhomocysteine lyase activity
RP72_16485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RP72_16490	COG0288	reversible hydration of carbon dioxide
RP72_16495	COG0254	rRNA binding
RP72_16500	COG1271	oxidase subunit
RP72_16505	COG1294	oxidase, subunit
RP72_16515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RP72_16520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RP72_16520	COG1321	iron dependent repressor
RP72_16525	COG1121	(ABC) transporter
RP72_16530	COG0803	Belongs to the bacterial solute-binding protein 9 family
RP72_16535	COG4948	Mandelate Racemase Muconate Lactonizing
RP72_16540	COG0318	PFAM AMP-dependent synthetase and ligase
RP72_16545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RP72_16550	COG0596	Alpha beta hydrolase
RP72_16555	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RP72_16560	COG1169	isochorismate synthase
RP72_16565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RP72_16570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RP72_16575	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RP72_16580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RP72_16585	COG0438	transferase activity, transferring glycosyl groups
RP72_16595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RP72_16600	COG0438	transferase activity, transferring glycosyl groups
RP72_16605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RP72_16610	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
RP72_16615	COG0058	SHG alpha-glucan phosphorylase activity
RP72_16620	COG0297	glycogen (starch) synthase activity
RP72_16625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RP72_16630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RP72_16635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RP72_16765	COG3859	Proton-coupled thiamine transporter YuaJ
RP72_16770	COG1247	-acetyltransferase
RP72_16775	COG2268	Band 7 protein
RP72_16780	COG1585	Membrane protein implicated in regulation of membrane protease activity
RP72_16785	COG2318	DinB family
RP72_16795	COG1454	alcohol dehydrogenase
RP72_16805	COG1510	regulation of RNA biosynthetic process
RP72_16815	COG0569	domain protein
RP72_16820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RP72_16825	COG4682	membrane
RP72_16830	COG1705	Flagellar rod assembly protein muramidase FlgJ
RP72_16835	COG0477	Major facilitator Superfamily
RP72_16840	COG5553	Cysteine dioxygenase type I
RP72_16850	COG1968	undecaprenyl-diphosphatase activity
RP72_16855	COG0628	permease
RP72_16860	COG0673	inositol 2-dehydrogenase activity
RP72_16865	COG4806	L-rhamnose isomerase
RP72_16870	COG3254	rhamnose metabolic process
RP72_16875	COG1070	Carbohydrate kinase
RP72_16880	COG1349	DNA-binding transcription factor activity
RP72_16885	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_16885	COG3347	Dehydrogenase
RP72_16890	COG0840	transmembrane signaling receptor activity
RP72_16895	COG0840	transmembrane signaling receptor activity
RP72_16900	COG0840	transmembrane signaling receptor activity
RP72_16905	COG0840	transmembrane signaling receptor activity
RP72_16920	COG0432	Pfam Uncharacterised protein family UPF0047
RP72_16925	COG0366	Alpha amylase catalytic
RP72_16930	COG1253	flavin adenine dinucleotide binding
RP72_16935	COG2738	Putative neutral zinc metallopeptidase
RP72_16950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RP72_16965	COG0166	Belongs to the GPI family
RP72_16970	COG1979	alcohol dehydrogenase
RP72_16975	COG1979	alcohol dehydrogenase
RP72_16980	COG2155	Conserved Protein
RP72_16985	COG1098	S1 RNA binding domain
RP72_16990	COG0436	Aminotransferase
RP72_16995	COG1522	sequence-specific DNA binding
RP72_17000	COG2267	carboxylic ester hydrolase activity
RP72_17010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RP72_17015	COG2205	protein histidine kinase activity
RP72_17025	COG5018	Exonuclease
RP72_17035	COG2814	Major facilitator Superfamily
RP72_17040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RP72_17045	COG3011	Protein conserved in bacteria
RP72_17055	COG3290	protein histidine kinase activity
RP72_17060	COG4565	transcriptional regulatory protein
RP72_17085	COG3493	citrate carrier protein
RP72_17095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RP72_17095	COG2111	Na H antiporter
RP72_17100	COG2111	Na H antiporter
RP72_17105	COG1006	Multisubunit Na H antiporter MnhC subunit
RP72_17110	COG0651	ATP synthesis coupled electron transport
RP72_17115	COG1863	multisubunit Na H antiporter MnhE subunit
RP72_17120	COG2212	antiporter activity
RP72_17125	COG1320	monovalent cation:proton antiporter activity
RP72_17130	COG2050	protein possibly involved in aromatic compounds catabolism
RP72_17135	COG2197	response regulator
RP72_17140	COG4585	Histidine kinase
RP72_17150	COG0142	geranyltranstransferase activity
RP72_17165	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
RP72_17170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RP72_17175	COG1335	isochorismatase
RP72_17180	COG5506	Protein of unknown function (DUF1694)
RP72_17195	COG0628	permease
RP72_17210	COG1418	mRNA catabolic process
RP72_17215	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_17225	COG1511	domain protein
RP72_17230	COG0433	COG0433 Predicted ATPase
RP72_17230	COG1674	ftsk spoiiie
RP72_17235	COG4499	WXG100 protein secretion system (Wss), protein YukC
RP72_17240	COG5417	Belongs to the EsaB family
RP72_17245	COG4842	Belongs to the WXG100 family
RP72_17250	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RP72_17250	COG2508	Transcriptional regulator
RP72_17255	COG0686	Belongs to the AlaDH PNT family
RP72_17260	COG5634	Uncharacterized conserved protein (DUF2278)
RP72_17265	COG3251	PFAM MbtH domain protein
RP72_17270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_17275	COG1535	isochorismatase
RP72_17275	COG3433	isochorismatase activity
RP72_17280	COG1021	2,3-dihydroxybenzoate-AMP ligase
RP72_17285	COG1169	isochorismate synthase
RP72_17290	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_17295	COG2819	hydrolase of the alpha beta superfamily
RP72_17300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RP72_17305	COG1268	BioY protein
RP72_17310	COG2056	Na+-H+ antiporter family
RP72_17315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RP72_17320	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
RP72_17325	COG3584	3D domain protein
RP72_17340	COG1252	NADH dehydrogenase
RP72_17345	COG0492	ferredoxin-NADP+ reductase activity
RP72_17355	COG0516	GMP reductase activity
RP72_17360	COG2808	Putative FMN-binding domain
RP72_17365	COG0456	acetyltransferase
RP72_17370	COG0316	Belongs to the HesB IscA family
RP72_17375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RP72_17380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RP72_17385	COG4844	belongs to the
RP72_17390	COG1252	NADH dehydrogenase
RP72_17395	COG4837	Protein of unknown function (DUF1462)
RP72_17400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RP72_17405	COG0823	Involved in the tonB-independent uptake of proteins
RP72_17405	COG4946	Tricorn protease homolog
RP72_17405	COG1506	peptidase
RP72_17410	COG0083	homoserine kinase activity
RP72_17415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RP72_17420	COG0460	homoserine dehydrogenase
RP72_17425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RP72_17430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RP72_17435	COG0647	UMP catabolic process
RP72_17440	COG2445	Protein of unknown function DUF86
RP72_17445	COG4470	Protein conserved in bacteria
RP72_17455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RP72_17460	COG0739	heme binding
RP72_17470	COG3377	Domain of unknown function (DUF1805)
RP72_17475	COG0737	Belongs to the 5'-nucleotidase family
RP72_17480	COG0730	response to heat
RP72_17485	COG1801	Protein of unknown function DUF72
RP72_17495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RP72_17500	COG2508	Transcriptional regulator
RP72_17505	COG2233	PERMEase
RP72_17510	COG2233	PERMEase
RP72_17515	COG3195	allantoin biosynthetic process
RP72_17515	COG3648	Uricase
RP72_17520	COG2351	hydroxyisourate hydrolase activity
RP72_17530	COG2080	2 iron, 2 sulfur cluster binding
RP72_17535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RP72_17540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RP72_17545	COG2068	MobA-Related Protein
RP72_17550	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RP72_17555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RP72_17560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RP72_17570	COG2356	endonuclease I
RP72_17575	COG3842	ATPase activity
RP72_17580	COG2188	Transcriptional regulator
RP72_17585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RP72_17590	COG0395	ABC-type sugar transport system, permease component
RP72_17595	COG1175	transmembrane transport
RP72_17600	COG1653	transport
RP72_17605	COG2222	sugar isomerase
RP72_17610	COG0322	excinuclease ABC activity
RP72_17615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RP72_17630	COG0346	lactoylglutathione lyase activity
RP72_17635	COG0640	Transcriptional regulator
RP72_17640	COG0719	Fe-S assembly protein
RP72_17645	COG0822	iron-sulfur transferase activity
RP72_17650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RP72_17655	COG0719	Fe-S assembly protein
RP72_17660	COG0396	ATPase activity
RP72_17670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RP72_17675	COG1464	Belongs to the NlpA lipoprotein family
RP72_17680	COG2011	ABC-type metal ion transport system permease component
RP72_17685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RP72_17695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RP72_17700	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RP72_17710	COG0509	glycine decarboxylation via glycine cleavage system
RP72_17715	COG1393	Belongs to the ArsC family
RP72_17720	COG1960	acyl-CoA dehydrogenase activity
RP72_17725	COG0183	Belongs to the thiolase family
RP72_17730	COG1024	Enoyl-CoA hydratase
RP72_17730	COG1250	3-hydroxyacyl-CoA dehydrogenase
RP72_17740	COG0506	proline dehydrogenase activity
RP72_17750	COG5577	PFAM Coat F domain
RP72_17755	COG1846	Transcriptional regulator
RP72_17760	COG0477	Major facilitator Superfamily
RP72_17765	COG1942	4-Oxalocrotonate Tautomerase
RP72_17770	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_17775	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_17780	COG0583	DNA-binding transcription factor activity
RP72_17790	COG1120	ATPase activity
RP72_17810	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_17815	COG0783	Belongs to the Dps family
RP72_17820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RP72_17825	COG0745	RESPONSE REGULATOR receiver
RP72_17830	COG2770	Histidine kinase
RP72_17830	COG2205	protein histidine kinase activity
RP72_17840	COG1309	transcriptional regulator
RP72_17845	COG0114	fumarate hydratase activity
RP72_17855	COG0697	spore germination
RP72_17860	COG0814	amino acid
RP72_17870	COG2197	response regulator
RP72_17875	COG4585	Histidine kinase
RP72_17880	COG4758	membrane
RP72_17885	COG3595	metallopeptidase activity
RP72_17890	COG1842	Phage shock protein A
RP72_17895	COG4758	membrane
RP72_17900	COG2814	Major facilitator Superfamily
RP72_17905	COG2096	Adenosyltransferase
RP72_17910	COG1120	ATPase activity
RP72_17915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_17920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RP72_17930	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_17935	COG3386	PFAM SMP-30 Gluconolaconase
RP72_17940	COG2205	protein histidine kinase activity
RP72_17945	COG0745	RESPONSE REGULATOR receiver
RP72_17955	COG1191	sigma factor activity
RP72_17965	COG2140	Oxalate decarboxylase
RP72_17975	COG0577	efflux transmembrane transporter activity
RP72_17980	COG1136	(ABC) transporter
RP72_17985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RP72_17990	COG1120	ATPase activity
RP72_17995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_18000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RP72_18005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RP72_18015	COG0531	amino acid
RP72_18025	COG1988	membrane-bound metal-dependent
RP72_18030	COG1368	sulfuric ester hydrolase activity
RP72_18035	COG1910	domain protein
RP72_18040	COG0725	ABC transporter, periplasmic molybdate-binding protein
RP72_18045	COG4149	molybdate abc transporter
RP72_18050	COG0656	L-ascorbic acid biosynthetic process
RP72_18060	COG0025	NhaP-type Na H and K H
RP72_18065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RP72_18070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RP72_18075	COG3973	AAA domain
RP72_18080	COG2860	membrane
RP72_18085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RP72_18090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RP72_18095	COG2217	Heavy metal translocating P-type atpase
RP72_18100	COG2217	Heavy metal translocating P-type atpase
RP72_18105	COG2608	mercury ion transmembrane transporter activity
RP72_18110	COG1937	Protein conserved in bacteria
RP72_18115	COG0673	inositol 2-dehydrogenase activity
RP72_18120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RP72_18125	COG1289	transmembrane transporter activity
RP72_18135	COG2076	Multidrug Resistance protein
RP72_18140	COG1309	transcriptional regulator
RP72_18145	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_18150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RP72_18155	COG0557	exoribonuclease II activity
RP72_18160	COG1647	Serine aminopeptidase, S33
RP72_18165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RP72_18170	COG0596	Alpha beta hydrolase
RP72_18175	COG1476	TRANSCRIPTIONal
RP72_18180	COG1396	sequence-specific DNA binding
RP72_18185	COG1396	sequence-specific DNA binding
RP72_18190	COG1733	regulation of RNA biosynthetic process
RP72_18195	COG0840	transmembrane signaling receptor activity
RP72_18200	COG1174	glycine betaine transport
RP72_18205	COG1732	Glycine betaine
RP72_18210	COG1174	glycine betaine transport
RP72_18215	COG1125	glycine betaine transport
RP72_18215	COG0517	IMP dehydrogenase activity
RP72_18220	COG1510	regulation of RNA biosynthetic process
RP72_18240	COG5658	integral membrane protein
RP72_18245	COG0640	Transcriptional regulator
RP72_18250	COG1174	glycine betaine transport
RP72_18255	COG1732	Glycine betaine
RP72_18260	COG1174	glycine betaine transport
RP72_18265	COG1125	glycine betaine transport
RP72_18265	COG0517	IMP dehydrogenase activity
RP72_18270	COG1510	regulation of RNA biosynthetic process
RP72_18275	COG2095	MarC family integral membrane protein
RP72_18285	COG3064	Membrane
RP72_18290	COG4640	response to antibiotic
RP72_18295	COG0456	acetyltransferase
RP72_18300	COG0148	phosphopyruvate hydratase activity
RP72_18305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RP72_18310	COG0149	triose-phosphate isomerase activity
RP72_18315	COG0126	phosphoglycerate kinase activity
RP72_18325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RP72_18330	COG2390	Transcriptional regulator
RP72_18335	COG2814	Major facilitator Superfamily
RP72_18340	COG1609	Transcriptional regulator
RP72_18345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RP72_18350	COG0583	DNA-binding transcription factor activity
RP72_18355	COG0697	spore germination
RP72_18360	COG1113	amino acid transport
RP72_18365	COG3858	chitin binding
RP72_18370	COG1556	Lactate utilization protein
RP72_18375	COG1139	Iron-sulfur cluster binding protein
RP72_18380	COG0247	lactate metabolic process
RP72_18385	COG2197	response regulator
RP72_18390	COG4585	Histidine kinase
RP72_18395	COG0842	Transport permease protein
RP72_18400	COG1131	(ABC) transporter
RP72_18405	COG0596	Alpha beta hydrolase
RP72_18410	COG2208	phosphoserine phosphatase activity
RP72_18415	COG3867	Arabinogalactan endo-beta-1,4-galactanase
RP72_18420	COG1874	Beta-galactosidase
RP72_18425	COG3833	ABC-type maltose transport systems, permease component
RP72_18430	COG1175	transmembrane transport
RP72_18435	COG2182	Extracellular solute-binding protein
RP72_18440	COG1609	Transcriptional regulator
RP72_18445	COG2186	Transcriptional regulator
RP72_18450	COG1620	l-lactate permease
RP72_18455	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RP72_18465	COG5039	Polysaccharide pyruvyl transferase
RP72_18470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RP72_18475	COG0110	maltose O-acetyltransferase activity
RP72_18480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RP72_18485	COG2244	polysaccharide biosynthetic process
RP72_18490	COG1216	Glycosyl transferase, family 2
RP72_18495	COG5039	Polysaccharide pyruvyl transferase
RP72_18500	COG1216	Glycosyl transferase, family 2
RP72_18510	COG0438	transferase activity, transferring glycosyl groups
RP72_18515	COG1215	transferase activity, transferring glycosyl groups
RP72_18520	COG0438	transferase activity, transferring glycosyl groups
RP72_18525	COG1086	Polysaccharide biosynthesis protein
RP72_18530	COG0489	protein tyrosine kinase activity
RP72_18535	COG3944	biosynthesis protein
RP72_18540	COG1396	sequence-specific DNA binding
RP72_18545	COG2272	Belongs to the type-B carboxylesterase lipase family
RP72_18555	COG3479	Phenolic acid decarboxylase
RP72_18565	COG1794	racemase activity, acting on amino acids and derivatives
RP72_18570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RP72_18575	COG1621	beta-fructofuranosidase activity
RP72_18580	COG1621	beta-fructofuranosidase activity
RP72_18585	COG0531	amino acid
RP72_18590	COG1309	transcriptional regulator
RP72_18595	COG2076	Multidrug Resistance protein
RP72_18600	COG2076	Multidrug Resistance protein
RP72_18610	COG0277	FAD linked oxidase domain protein
RP72_18615	COG3621	Patatin-like phospholipase
RP72_18625	COG0740	serine-type endopeptidase activity
RP72_18630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RP72_18635	COG0366	Alpha amylase catalytic
RP72_18645	COG5521	maltodextrose utilization protein MalA
RP72_18650	COG3833	ABC-type maltose transport systems, permease component
RP72_18655	COG1175	transmembrane transport
RP72_18660	COG2182	Extracellular solute-binding protein
RP72_18665	COG0366	Alpha amylase catalytic
RP72_18670	COG1609	Transcriptional regulator
RP72_18675	COG1611	Belongs to the LOG family
RP72_18680	COG1694	Mazg nucleotide pyrophosphohydrolase
RP72_18685	COG0659	secondary active sulfate transmembrane transporter activity
RP72_18690	COG0288	reversible hydration of carbon dioxide
RP72_18695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RP72_18700	COG0577	efflux transmembrane transporter activity
RP72_18705	COG1136	(ABC) transporter
RP72_18710	COG5002	protein histidine kinase activity
RP72_18715	COG0745	RESPONSE REGULATOR receiver
RP72_18725	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RP72_18730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_18735	COG1481	regulation of sporulation
RP72_18740	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RP72_18745	COG1660	Displays ATPase and GTPase activities
RP72_18750	COG1051	belongs to the nudix hydrolase family
RP72_18755	COG0492	ferredoxin-NADP+ reductase activity
RP72_18760	COG3883	PFAM NLP P60 protein
RP72_18760	COG0791	NLP P60 protein
RP72_18765	COG0457	Tetratricopeptide repeat
RP72_18770	COG1132	(ABC) transporter
RP72_18790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RP72_18790	COG0140	phosphoribosyl-ATP diphosphatase activity
RP72_18795	COG0107	imidazoleglycerol-phosphate synthase activity
RP72_18800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RP72_18805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RP72_18810	COG0131	Imidazoleglycerol-phosphate dehydratase
RP72_18815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RP72_18820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RP72_18825	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RP72_18830	COG4990	cell redox homeostasis
RP72_18835	COG5297	Belongs to the glycosyl hydrolase family 6
RP72_18840	COG0110	maltose O-acetyltransferase activity
RP72_18845	COG0546	phosphoglycolate phosphatase activity
RP72_18850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RP72_18855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RP72_18860	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RP72_18865	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RP72_18870	COG0363	glucosamine-6-phosphate deaminase activity
RP72_18880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RP72_18885	COG1846	Transcriptional regulator
RP72_18890	COG2124	cytochrome p450
RP72_18900	COG1846	Transcriptional regulator
RP72_18905	COG2814	Major facilitator Superfamily
RP72_18910	COG1950	PFAM Membrane protein of
RP72_18915	COG1983	PspC domain protein
RP72_18920	COG3595	metallopeptidase activity
RP72_18935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RP72_18940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RP72_18945	COG0556	nucleotide-excision repair
RP72_18950	COG4897	Protein conserved in bacteria
RP72_18955	COG0574	Belongs to the PEP-utilizing enzyme family
RP72_18955	COG3848	Pyruvate phosphate dikinase
RP72_18960	COG1309	transcriptional regulator
RP72_18965	COG2814	Major facilitator Superfamily
RP72_18970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RP72_18980	COG3409	Peptidoglycan-binding domain 1 protein
RP72_18980	COG0793	Belongs to the peptidase S41A family
RP72_18985	COG2177	Part of the ABC transporter FtsEX involved in
RP72_18990	COG2884	Cell division ATP-binding protein ftsE
RP72_18995	COG2010	Cytochrome c
RP72_19000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RP72_19005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RP72_19010	COG0653	protein targeting
RP72_19015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RP72_19030	COG1516	flagellar protein fliS
RP72_19035	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RP72_19040	COG1334	flagellar protein FlaG
RP72_19045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RP72_19050	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RP72_19055	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
RP72_19065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RP72_19070	COG1256	bacterial-type flagellum assembly
RP72_19070	COG4786	Flagellar basal body rod
RP72_19075	COG3418	PFAM FlgN family protein
RP72_19080	COG2747	anti-sigma28 factor FlgM
RP72_19090	COG1040	competence protein
RP72_19100	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RP72_19105	COG1307	EDD domain protein, DegV family
RP72_19110	COG2197	response regulator
RP72_19115	COG4585	Histidine kinase
RP72_19120	COG1739	Uncharacterized protein family UPF0029
RP72_19125	COG1316	TRANSCRIPTIONal
RP72_19130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RP72_19135	COG0438	transferase activity, transferring glycosyl groups
RP72_19140	COG1215	transferase activity, transferring glycosyl groups
RP72_19145	COG3206	protein involved in exopolysaccharide biosynthesis
RP72_19150	COG3307	-O-antigen
RP72_19155	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RP72_19160	COG0438	transferase activity, transferring glycosyl groups
RP72_19160	COG0297	glycogen (starch) synthase activity
RP72_19165	COG2244	polysaccharide biosynthetic process
RP72_19170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RP72_19180	COG2247	cell wall binding repeat
RP72_19180	COG0860	N-Acetylmuramoyl-L-alanine amidase
RP72_19185	COG2247	cell wall binding repeat
RP72_19185	COG2385	sporulation resulting in formation of a cellular spore
RP72_19195	COG1316	TRANSCRIPTIONal
RP72_19200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RP72_19205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RP72_19210	COG1215	transferase activity, transferring glycosyl groups
RP72_19210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RP72_19215	COG0463	Glycosyl transferase, family 2
RP72_19230	COG1134	teichoic acid transport
RP72_19235	COG1682	transport, permease protein
RP72_19240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RP72_19245	COG0438	transferase activity, transferring glycosyl groups
RP72_19250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RP72_19255	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RP72_19260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RP72_19270	COG4193	domain, Protein
RP72_19275	COG1482	cell wall glycoprotein biosynthetic process
RP72_19285	COG0697	spore germination
RP72_19290	COG0814	amino acid
RP72_19300	COG2814	Major facilitator Superfamily
RP72_19305	COG1316	TRANSCRIPTIONal
RP72_19310	COG0561	phosphatase activity
RP72_19315	COG0791	NLP P60 protein
RP72_19325	COG2843	Capsule synthesis protein
RP72_19335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RP72_19340	COG1609	Transcriptional regulator
RP72_19345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RP72_19350	COG1869	D-ribose catabolic process
RP72_19355	COG1129	ABC transporter
RP72_19360	COG1172	Belongs to the binding-protein-dependent transport system permease family
RP72_19365	COG1879	ABC-type sugar transport system periplasmic component
RP72_19370	COG3103	Sh3 type 3 domain protein
RP72_19380	COG2249	NAD(P)H dehydrogenase (quinone) activity
RP72_19385	COG3527	Alpha-acetolactate decarboxylase
RP72_19390	COG0028	Belongs to the TPP enzyme family
RP72_19395	COG0583	DNA-binding transcription factor activity
RP72_19400	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RP72_19415	COG5337	Spore coat protein CotH
RP72_19425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RP72_19435	COG0405	Gamma-glutamyltransferase
RP72_19440	COG1522	sequence-specific DNA binding
RP72_19445	COG2059	Chromate
RP72_19450	COG2059	Chromate
RP72_19460	COG0655	NAD(P)H dehydrogenase (quinone) activity
RP72_19465	COG0583	DNA-binding transcription factor activity
RP72_19470	COG1515	deoxyribonuclease V activity
RP72_19475	COG2849	repeat protein
RP72_19480	COG5444	nuclease activity
RP72_19495	COG3878	Protein conserved in bacteria
RP72_19500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RP72_19505	COG4464	protein tyrosine phosphatase activity
RP72_19510	COG0489	protein tyrosine kinase activity
RP72_19515	COG3944	biosynthesis protein
RP72_19525	COG4715	Zinc finger, swim domain protein
RP72_19530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RP72_19535	COG0561	phosphatase activity
RP72_19540	COG1349	DNA-binding transcription factor activity
RP72_19545	COG0629	single-stranded DNA binding
RP72_19560	COG3764	Sortase (surface protein transpeptidase)
RP72_19565	COG0745	RESPONSE REGULATOR receiver
RP72_19565	COG2972	Histidine kinase
RP72_19570	COG1970	mechanosensitive ion channel activity
RP72_19575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RP72_19580	COG0457	Tetratricopeptide repeat
RP72_19585	COG4786	Flagellar basal body rod
RP72_19590	COG4786	Flagellar basal body rod
RP72_19595	COG1077	Cell shape determining protein MreB Mrl
RP72_19600	COG1609	Transcriptional regulator
RP72_19605	COG1846	Transcriptional regulator
RP72_19610	COG2814	Major facilitator Superfamily
RP72_19615	COG3420	alginic acid biosynthetic process
RP72_19620	COG1953	Uracil, thiamine, allantoin
RP72_19625	COG0477	Major facilitator Superfamily
RP72_19630	COG1335	isochorismatase
RP72_19640	COG0004	ammonium transporteR
RP72_19645	COG0347	Belongs to the P(II) protein family
RP72_19650	COG0671	phosphoesterase, PA-phosphatase related
RP72_19660	COG0739	heme binding
RP72_19665	COG1247	-acetyltransferase
RP72_19685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RP72_19690	COG0789	Transcriptional regulator
RP72_19700	COG2910	NAD(P)H-binding
RP72_19705	COG1959	2 iron, 2 sulfur cluster binding
RP72_19710	COG0804	urea catabolic process
RP72_19715	COG0832	Belongs to the urease beta subunit family
RP72_19720	COG0831	urea catabolic process
RP72_19730	COG3237	CsbD-like
RP72_19735	COG1994	Peptidase M50
RP72_19740	COG0457	Tetratricopeptide repeat
RP72_19745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RP72_19750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RP72_19760	COG2304	oxidoreductase activity
RP72_19770	COG2304	oxidoreductase activity
RP72_19775	COG2385	sporulation resulting in formation of a cellular spore
RP72_19780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RP72_19790	COG4836	Membrane
RP72_19800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RP72_19805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RP72_19810	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RP72_19815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RP72_19820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RP72_19825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RP72_19835	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RP72_19840	COG0356	it plays a direct role in the translocation of protons across the membrane
RP72_19850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RP72_19855	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RP72_19860	COG4475	Protein of unknown function (DUF436)
RP72_19865	COG0698	ribose 5-phosphate isomerase
RP72_19870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RP72_19875	COG1971	Probably functions as a manganese efflux pump
RP72_19880	COG0009	L-threonylcarbamoyladenylate synthase
RP72_19885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RP72_19905	COG2890	protein-(glutamine-N5) methyltransferase activity
RP72_19910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RP72_19915	COG0346	lactoylglutathione lyase activity
RP72_19920	COG0789	Transcriptional regulator
RP72_19925	COG0679	Auxin Efflux Carrier
RP72_19930	COG0281	malic enzyme
RP72_19935	COG1435	thymidine kinase activity
RP72_19940	COG0254	rRNA binding
RP72_19945	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RP72_19955	COG1494	fructose-1,6-bisphosphatase
RP72_19960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RP72_19965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RP72_19970	COG0191	fructose-bisphosphate aldolase activity
RP72_19975	COG2204	response regulator
RP72_19980	COG4821	SIS domain
RP72_19985	COG0504	CTP synthase activity
RP72_19990	COG3343	RNA polymerase activity
RP72_19995	COG1960	acyl-CoA dehydrogenase activity
RP72_20000	COG2181	nitrate reductase activity
RP72_20000	COG0247	lactate metabolic process
RP72_20005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RP72_20010	COG4294	response to UV
RP72_20020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RP72_20025	COG1132	(ABC) transporter
RP72_20030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RP72_20035	COG2181	nitrate reductase activity
RP72_20040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RP72_20045	COG1140	nitrate reductase beta subunit
RP72_20050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RP72_20055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RP72_20065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RP72_20070	COG2223	nitrite transmembrane transporter activity
RP72_20075	COG0018	arginyl-trna synthetase
RP72_20080	COG4506	Protein conserved in bacteria
RP72_20090	COG0535	radical SAM domain protein
RP72_20100	COG1131	(ABC) transporter
RP72_20105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RP72_20110	COG0612	Peptidase, M16
RP72_20115	COG0612	Peptidase, M16
RP72_20125	COG3391	amine dehydrogenase activity
RP72_20130	COG3391	amine dehydrogenase activity
RP72_20140	COG0457	Tetratricopeptide repeat
RP72_20150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RP72_20155	COG0010	Belongs to the arginase family
RP72_20160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RP72_20165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RP72_20175	COG1994	Peptidase M50
RP72_20180	COG1942	4-Oxalocrotonate Tautomerase
RP72_20185	COG1846	Transcriptional regulator
RP72_20190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RP72_20200	COG0477	Major facilitator Superfamily
RP72_20205	COG1959	2 iron, 2 sulfur cluster binding
RP72_20210	COG3465	dGTPase activity
RP72_20215	COG1078	dGTPase activity
RP72_20220	COG4844	belongs to the
RP72_20230	COG0697	spore germination
RP72_20235	COG0095	Lipoate-protein ligase
RP72_20240	COG0583	DNA-binding transcription factor activity
RP72_20245	COG0280	phosphate acetyltransferase
RP72_20255	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_20260	COG0436	Aminotransferase
RP72_20265	COG2814	Major facilitator Superfamily
RP72_20270	COG0151	Belongs to the GarS family
RP72_20275	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_20280	COG1917	Cupin 2, conserved barrel domain protein
RP72_20285	COG0077	Prephenate dehydratase
RP72_20290	COG2814	Major facilitator Superfamily
RP72_20295	COG0833	amino acid
RP72_20300	COG4187	Peptidase family M20/M25/M40
RP72_20305	COG1012	belongs to the aldehyde dehydrogenase family
RP72_20310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RP72_20320	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RP72_20325	COG1091	dTDP-4-dehydrorhamnose reductase activity
RP72_20330	COG1088	dTDP-glucose 4,6-dehydratase activity
RP72_20335	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RP72_20340	COG3980	spore coat polysaccharide biosynthesis protein
RP72_20345	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
RP72_20350	COG2089	acid synthase
RP72_20355	COG0456	acetyltransferase
RP72_20360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RP72_20365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RP72_20370	COG0463	Glycosyl transferase, family 2
RP72_20385	COG2363	Small membrane protein
RP72_20390	COG2233	PERMEase
RP72_20400	COG1012	belongs to the aldehyde dehydrogenase family
RP72_20405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RP72_20410	COG1216	Glycosyl transferase, family 2
RP72_20425	COG1695	Transcriptional regulator
RP72_20430	COG0351	phosphomethylpyrimidine kinase
RP72_20440	COG1621	beta-fructofuranosidase activity
RP72_20445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_20445	COG1263	PTS System
RP72_20450	COG2116	formate transmembrane transporter activity
RP72_20455	COG3711	transcriptional antiterminator
RP72_20465	COG1404	Belongs to the peptidase S8 family
RP72_20470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RP72_20475	COG0778	Nitroreductase
RP72_20480	COG0772	Belongs to the SEDS family
RP72_20490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RP72_20495	COG1845	cytochrome c oxidase, subunit III
RP72_20500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RP72_20505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RP72_20510	COG2261	transglycosylase associated protein
RP72_20515	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
RP72_20520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RP72_20525	COG2246	polysaccharide biosynthetic process
RP72_20530	COG1309	transcriptional regulator
RP72_20540	COG3162	membrane
RP72_20545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RP72_20550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RP72_20555	COG2837	iron assimilation
RP72_20560	COG2822	iron ion transport
RP72_20565	COG0672	)-iron permease
RP72_20570	COG0352	thiamine-phosphate diphosphorylase activity
RP72_20575	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RP72_20580	COG0583	DNA-binding transcription factor activity
RP72_20585	COG1380	Effector of murein hydrolase LrgA
RP72_20590	COG1346	cytolysis
RP72_20595	COG2814	Major facilitator Superfamily
RP72_20600	COG4895	conserved protein (DUF2196)
RP72_20605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RP72_20610	COG0346	lactoylglutathione lyase activity
RP72_20620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RP72_20625	COG1404	Belongs to the peptidase S8 family
RP72_20630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_20630	COG1263	PTS System
RP72_20635	COG3711	transcriptional antiterminator
RP72_20640	COG1442	glycosyl transferase family 8
RP72_20645	COG5522	Integral membrane protein (intg_mem_TP0381)
RP72_20650	COG1846	Transcriptional regulator
RP72_20655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RP72_20660	COG2234	aminopeptidase activity
RP72_20665	COG2357	RelA SpoT domain protein
RP72_20670	COG1575	Belongs to the MenA family. Type 1 subfamily
RP72_20685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RP72_20690	COG1696	Membrane protein involved in D-alanine export
RP72_20695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RP72_20700	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RP72_20705	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
RP72_20710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RP72_20715	COG1486	melibiose metabolic process
RP72_20720	COG1447	Phosphotransferase system cellobiose-specific component IIA
RP72_20725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RP72_20730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RP72_20735	COG3711	transcriptional antiterminator
RP72_20735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RP72_20745	COG2094	Belongs to the DNA glycosylase MPG family
RP72_20750	COG0753	catalase activity
RP72_20755	COG2814	Major facilitator Superfamily
RP72_20760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RP72_20765	COG1131	(ABC) transporter
RP72_20785	COG1595	DNA-templated transcription, initiation
RP72_20790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RP72_20795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RP72_20800	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RP72_20805	COG4988	ABC transporter
RP72_20810	COG1294	oxidase, subunit
RP72_20815	COG1271	oxidase subunit
RP72_20820	COG3493	citrate carrier protein
RP72_20825	COG0501	Belongs to the peptidase M48B family
RP72_20835	COG0726	polysaccharide deacetylase
RP72_20840	COG3842	ATPase activity
RP72_20845	COG2508	Transcriptional regulator
RP72_20850	COG1012	belongs to the aldehyde dehydrogenase family
RP72_20855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RP72_20865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RP72_20870	COG1881	PFAM PEBP family protein
RP72_20875	COG0583	DNA-binding transcription factor activity
RP72_20885	COG4585	Histidine kinase
RP72_20890	COG2197	response regulator
RP72_20895	COG2195	Cleaves the N-terminal amino acid of tripeptides
RP72_20910	COG4894	glucomannan catabolic process
RP72_20915	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RP72_20920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RP72_20925	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_20930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RP72_20935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RP72_20940	COG2610	gluconate transmembrane transporter activity
RP72_20950	COG0500	methyltransferase
RP72_20955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RP72_20975	COG0693	protein deglycase activity
RP72_20975	COG0753	catalase activity
RP72_20980	COG2851	Citrate transporter
RP72_20985	COG2273	Hydrolase Family 16
RP72_20990	COG3711	transcriptional antiterminator
RP72_21000	COG2270	Major facilitator Superfamily
RP72_21005	COG0513	Belongs to the DEAD box helicase family
RP72_21010	COG3401	FG-GAP repeat protein
RP72_21010	COG2755	lipolytic protein G-D-S-L family
RP72_21065	COG3209	COG3209 Rhs family protein
RP72_21070	COG0697	spore germination
RP72_21075	COG0589	response to stress
RP72_21080	COG2723	6-phospho-beta-galactosidase activity
RP72_21085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RP72_21085	COG2190	(PTS) system
RP72_21085	COG1263	PTS System
RP72_21100	COG5444	nuclease activity
RP72_21115	COG3507	Belongs to the glycosyl hydrolase 43 family
RP72_21130	COG2986	histidine ammonia-lyase
RP72_21135	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RP72_21140	COG1228	amidohydrolase
RP72_21145	COG0010	Belongs to the arginase family
RP72_21150	COG0833	amino acid
RP72_21155	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RP72_21160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RP72_21165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RP72_21170	COG2390	Transcriptional regulator
RP72_21180	COG3192	ethanolamine utilization protein
RP72_21185	COG2079	MmgE PrpD family protein
RP72_21195	COG1126	abc transporter atp-binding protein
RP72_21200	COG0765	amino acid transport
RP72_21205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RP72_21225	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
RP72_21230	COG0561	phosphatase activity
RP72_21260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RP72_21265	COG5294	Protein conserved in bacteria
RP72_21270	COG0577	efflux transmembrane transporter activity
RP72_21275	COG1136	(ABC) transporter
RP72_21280	COG2205	protein histidine kinase activity
RP72_21285	COG0745	RESPONSE REGULATOR receiver
RP72_21290	COG0191	fructose-bisphosphate aldolase activity
RP72_21295	COG1082	Xylose isomerase domain protein TIM barrel
RP72_21300	COG1082	Xylose isomerase domain protein TIM barrel
RP72_21305	COG0673	inositol 2-dehydrogenase activity
RP72_21310	COG2814	Major facilitator Superfamily
RP72_21315	COG1082	Xylose isomerase domain protein TIM barrel
RP72_21320	COG3962	Belongs to the TPP enzyme family
RP72_21325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RP72_21330	COG3718	enzyme involved in inositol metabolism
RP72_21335	COG1012	belongs to the aldehyde dehydrogenase family
RP72_21340	COG1349	DNA-binding transcription factor activity
RP72_21345	COG0667	Aldo Keto reductase
RP72_21360	COG2814	Major facilitator Superfamily
RP72_21365	COG0326	Molecular chaperone. Has ATPase activity
RP72_21375	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_21380	COG1309	transcriptional regulator
RP72_21385	COG1012	belongs to the aldehyde dehydrogenase family
RP72_21390	COG0456	acetyltransferase
RP72_21395	COG2850	peptidyl-arginine hydroxylation
RP72_21400	COG2226	methyltransferase
RP72_21415	COG0367	asparagine synthase
RP72_21420	COG2814	Major facilitator Superfamily
RP72_21425	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RP72_21435	COG1714	RDD family
RP72_21440	COG2311	Membrane
RP72_21445	COG1917	Cupin 2, conserved barrel domain protein
RP72_21450	COG1309	transcriptional regulator
RP72_21455	COG1028	Short-chain dehydrogenase reductase Sdr
RP72_21460	COG1846	Transcriptional regulator
RP72_21465	COG1380	Effector of murein hydrolase LrgA
RP72_21470	COG1346	cytolysis
RP72_21475	COG5039	Polysaccharide pyruvyl transferase
RP72_21480	COG1929	Belongs to the glycerate kinase type-1 family
RP72_21485	COG1802	Transcriptional regulator
RP72_21490	COG1070	Carbohydrate kinase
RP72_21495	COG2610	gluconate transmembrane transporter activity
RP72_21500	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RP72_21505	COG0450	alkyl hydroperoxide reductase
RP72_21510	COG3634	alkyl hydroperoxide reductase activity
RP72_21515	COG2723	6-phospho-beta-galactosidase activity
RP72_21520	COG2190	(PTS) system
RP72_21525	COG2188	Transcriptional regulator
RP72_21540	COG1131	(ABC) transporter
RP72_21545	COG1994	Peptidase M50
RP72_21550	COG0535	radical SAM domain protein
RP72_21560	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
RP72_21565	COG5293	efflux transmembrane transporter activity
RP72_21580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RP72_21590	COG1063	alcohol dehydrogenase
RP72_21610	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
RP72_21615	COG0456	acetyltransferase
RP72_21620	COG0457	Tetratricopeptide repeat
RP72_21630	COG0010	Belongs to the arginase family
RP72_21635	COG0833	amino acid
RP72_21640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RP72_21645	COG3829	transcription factor binding
RP72_21650	COG5002	protein histidine kinase activity
RP72_21660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RP72_21665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RP72_21670	COG4853	Protein conserved in bacteria
RP72_21675	COG4863	YycH protein
RP72_21680	COG5002	protein histidine kinase activity
RP72_21685	COG0745	RESPONSE REGULATOR receiver
RP72_21715	COG0346	lactoylglutathione lyase activity
RP72_21720	COG0305	Participates in initiation and elongation during chromosome replication
RP72_21740	COG3093	addiction module antidote protein HigA
RP72_21745	COG2807	transmembrane transport
RP72_21750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RP72_21755	COG0359	binds to the 23S rRNA
RP72_21760	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RP72_21765	COG4241	membrane
RP72_21775	COG5577	PFAM Coat F domain
RP72_21780	COG1733	regulation of RNA biosynthetic process
RP72_21785	COG1227	inorganic diphosphatase activity
RP72_21800	COG2271	Major facilitator Superfamily
RP72_21810	COG4319	ketosteroid isomerase
RP72_21840	COG1131	(ABC) transporter
RP72_21850	COG4319	ketosteroid isomerase
RP72_21855	COG1357	PFAM Pentapeptide repeats (8 copies)
RP72_21860	COG2814	Major facilitator Superfamily
RP72_21865	COG0583	DNA-binding transcription factor activity
RP72_21870	COG2153	protein acetylation
RP72_21880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RP72_21885	COG1846	Transcriptional regulator
RP72_21890	COG2153	protein acetylation
RP72_21895	COG2364	Membrane
RP72_21900	COG0456	acetyltransferase
RP72_21905	COG2315	Protein conserved in bacteria
RP72_21910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RP72_21915	COG2814	Major facilitator Superfamily
RP72_21920	COG1331	Highly conserved protein containing a thioredoxin domain
RP72_21925	COG0789	Transcriptional regulator
RP72_21930	COG0697	spore germination
RP72_21935	COG1331	Highly conserved protein containing a thioredoxin domain
RP72_21940	COG1266	CAAX protease self-immunity
RP72_21945	COG0477	Major facilitator Superfamily
RP72_21945	COG2814	Major facilitator Superfamily
RP72_21950	COG0110	maltose O-acetyltransferase activity
RP72_21955	COG0346	lactoylglutathione lyase activity
RP72_21960	COG1609	Transcriptional regulator
RP72_21965	COG0708	Exodeoxyribonuclease III
RP72_21970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RP72_21975	COG0629	single-stranded DNA binding
RP72_21980	COG0360	Binds together with S18 to 16S ribosomal RNA
RP72_21985	COG0012	GTP binding
RP72_21990	COG0243	molybdopterin cofactor binding
RP72_21995	COG4481	Protein conserved in bacteria
RP72_22000	COG3949	Membrane
RP72_22010	COG1475	DNA binding
RP72_22015	COG1192	Involved in chromosome partitioning
RP72_22025	COG1475	DNA binding
RP72_22030	COG0357	Ribosomal RNA small subunit methyltransferase G
RP72_22035	COG0445	tRNA wobble uridine modification
RP72_22040	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RP72_22045	COG1847	R3H domain protein
RP72_22050	COG0706	membrane insertase activity
RP72_22055	COG0594	ribonuclease P activity
RP72_22060	COG0230	Belongs to the bacterial ribosomal protein bL34 family