locus-tag	class	description
CXF51_00010	COG0592	DNA-directed DNA polymerase activity
CXF51_00015	COG2501	S4 domain
CXF51_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CXF51_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CXF51_00070	COG0516	GMP reductase activity
CXF51_00070	COG0517	IMP dehydrogenase activity
CXF51_00075	COG1686	Belongs to the peptidase S11 family
CXF51_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CXF51_00105	COG1428	Deoxynucleoside kinase
CXF51_00110	COG1388	LysM domain
CXF51_00110	COG3858	chitin binding
CXF51_00120	COG0590	tRNA wobble adenosine to inosine editing
CXF51_00205	COG3870	Protein conserved in bacteria
CXF51_00210	COG1728	Protein conserved in bacteria
CXF51_00215	COG0470	DNA polymerase III
CXF51_00220	COG1774	PSP1 C-terminal conserved region
CXF51_00225	COG4467	Involved in initiation control of chromosome replication
CXF51_00235	COG2827	Endonuclease containing a URI domain
CXF51_00280	COG4466	Protein conserved in bacteria
CXF51_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CXF51_00300	COG0251	oxidation-reduction process
CXF51_00305	COG2088	sporulation resulting in formation of a cellular spore
CXF51_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CXF51_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CXF51_00325	COG0193	aminoacyl-tRNA hydrolase activity
CXF51_00340	COG2002	toxin-antitoxin pair type II binding
CXF51_00345	COG2244	polysaccharide biosynthetic process
CXF51_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CXF51_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CXF51_00375	COG1098	S1 RNA binding domain
CXF51_00395	COG2304	oxidoreductase activity
CXF51_00405	COG0037	tRNA processing
CXF51_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CXF51_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CXF51_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CXF51_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXF51_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CXF51_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
CXF51_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXF51_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CXF51_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CXF51_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CXF51_00470	COG1396	sequence-specific DNA binding
CXF51_00560	COG4463	regulation of RNA biosynthetic process
CXF51_00565	COG3880	PFAM UvrB UvrC protein
CXF51_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CXF51_00575	COG0542	response to heat
CXF51_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CXF51_00590	COG4956	integral membrane protein (PIN domain superfamily)
CXF51_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CXF51_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CXF51_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CXF51_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CXF51_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXF51_00655	COG0250	Participates in transcription elongation, termination and antitermination
CXF51_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CXF51_00695	COG1358	cellular component organization or biogenesis
CXF51_00715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CXF51_00725	COG0051	transcription antitermination factor activity, RNA binding
CXF51_00730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CXF51_00735	COG0088	Forms part of the polypeptide exit tunnel
CXF51_00740	COG0089	rRNA binding
CXF51_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CXF51_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CXF51_00760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CXF51_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CXF51_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
CXF51_00775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CXF51_00780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CXF51_00790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CXF51_00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CXF51_00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CXF51_00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CXF51_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CXF51_00820	COG1841	ribosomal large subunit assembly
CXF51_00835	COG0563	adenylate kinase activity
CXF51_00840	COG0024	Methionine aminopeptidase
CXF51_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CXF51_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CXF51_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CXF51_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CXF51_00870	COG0202	RNA polymerase activity
CXF51_00875	COG0203	ribosomal protein L17
CXF51_00885	COG1122	ATPase activity
CXF51_00895	COG0101	tRNA pseudouridine synthase activity
CXF51_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CXF51_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CXF51_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXF51_00925	COG0489	protein tyrosine kinase activity
CXF51_00975	COG2856	Zn peptidase
CXF51_00985	COG1395	domain, Protein
CXF51_01040	COG0305	Participates in initiation and elongation during chromosome replication
CXF51_01050	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CXF51_01150	COG1783	phage Terminase large subunit
CXF51_01160	COG2369	cell adhesion
CXF51_01180	COG4653	Phage capsid family
CXF51_01260	COG3628	GPW Gp25 family protein
CXF51_01270	COG3778	Protein conserved in bacteria
CXF51_01310	COG1388	LysM domain
CXF51_01310	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXF51_01310	COG3409	Peptidoglycan-binding domain 1 protein
CXF51_01330	COG5444	nuclease activity
CXF51_01350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CXF51_01370	COG1395	domain, Protein
CXF51_01535	COG0659	secondary active sulfate transmembrane transporter activity
CXF51_01540	COG0385	Bile acid
CXF51_01545	COG2819	hydrolase of the alpha beta superfamily
CXF51_01550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXF51_01555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXF51_01580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXF51_01585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXF51_01585	COG1263	PTS System
CXF51_01590	COG1737	Transcriptional regulator
CXF51_01595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CXF51_01600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXF51_01605	COG1683	Conserved Protein
CXF51_01635	COG1595	DNA-templated transcription, initiation
CXF51_01640	COG5662	AntiSigma factor
CXF51_01645	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CXF51_01650	COG4856	YbbR-like protein
CXF51_01655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CXF51_01665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CXF51_01685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXF51_01690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CXF51_01710	COG5609	conserved protein (DUF2294)
CXF51_01715	COG0640	Transcriptional regulator
CXF51_01745	COG0642	Histidine kinase
CXF51_01785	COG2602	Beta-lactamase
CXF51_01790	COG2124	cytochrome p450
CXF51_01800	COG0531	amino acid
CXF51_01805	COG0584	glycerophosphoryl diester phosphodiesterase
CXF51_01810	COG2271	Major facilitator Superfamily
CXF51_01830	COG2271	Major facilitator Superfamily
CXF51_01840	COG1917	Cupin 2, conserved barrel domain protein
CXF51_01840	COG2207	Transcriptional regulator
CXF51_01845	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CXF51_01865	COG1183	phosphatidylcholine synthase activity
CXF51_01875	COG0688	phosphatidylethanolamine metabolic process
CXF51_01885	COG2312	Erythromycin esterase
CXF51_01890	COG2207	Transcriptional regulator
CXF51_01935	COG2040	homocysteine
CXF51_01950	COG2066	Belongs to the glutaminase family
CXF51_01960	COG0784	Response regulator, receiver
CXF51_01970	COG1012	belongs to the aldehyde dehydrogenase family
CXF51_01980	COG4948	Mandelate Racemase Muconate Lactonizing
CXF51_01995	COG3173	Aminoglycoside phosphotransferase
CXF51_02035	COG3773	Cell wall hydrolase
CXF51_02055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXF51_02060	COG0805	protein transport
CXF51_02065	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CXF51_02070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXF51_02075	COG0477	Major facilitator Superfamily
CXF51_02095	COG1714	RDD family
CXF51_02100	COG1405	negative regulation of cell septum assembly
CXF51_02100	COG3012	SEC-C Motif Domain Protein
CXF51_02105	COG3290	protein histidine kinase activity
CXF51_02110	COG3279	Response regulator of the LytR AlgR family
CXF51_02115	COG4555	ABC transporter
CXF51_02135	COG1595	DNA-templated transcription, initiation
CXF51_02140	COG1595	DNA-templated transcription, initiation
CXF51_02150	COG0457	Tetratricopeptide repeat
CXF51_02155	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_02160	COG0366	Alpha amylase catalytic
CXF51_02165	COG0803	Belongs to the bacterial solute-binding protein 9 family
CXF51_02170	COG1121	(ABC) transporter
CXF51_02185	COG2310	stress, protein
CXF51_02190	COG2310	stress, protein
CXF51_02215	COG0477	Major facilitator Superfamily
CXF51_02230	COG0640	Transcriptional regulator
CXF51_02235	COG4175	Glycine betaine
CXF51_02235	COG0517	IMP dehydrogenase activity
CXF51_02240	COG4176	ABC-type proline glycine betaine transport system permease component
CXF51_02245	COG2113	Glycine betaine
CXF51_02250	COG1473	amidohydrolase
CXF51_02265	COG0366	Alpha amylase catalytic
CXF51_02270	COG0039	L-malate dehydrogenase activity
CXF51_02280	COG2814	Major facilitator Superfamily
CXF51_02285	COG1846	Transcriptional regulator
CXF51_02290	COG1280	lysine exporter protein (LysE YggA)
CXF51_02295	COG3403	YqcI/YcgG family
CXF51_02300	COG1113	amino acid transport
CXF51_02305	COG3665	Urea carboxylase-associated protein
CXF51_02310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CXF51_02315	COG1660	Displays ATPase and GTPase activities
CXF51_02325	COG2226	methyltransferase
CXF51_02330	COG0583	DNA-binding transcription factor activity
CXF51_02335	COG3458	cephalosporin-C deacetylase activity
CXF51_02345	COG0506	proline dehydrogenase activity
CXF51_02350	COG1012	belongs to the aldehyde dehydrogenase family
CXF51_02360	COG2508	Transcriptional regulator
CXF51_02365	COG3689	TIGRFAM TIGR03943 family protein
CXF51_02370	COG0701	Predicted permease
CXF51_02390	COG2146	nitrite reductase [NAD(P)H] activity
CXF51_02420	COG1376	ErfK ybiS ycfS ynhG family protein
CXF51_02430	COG0523	cobalamin synthesis protein
CXF51_02440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXF51_02470	COG3290	protein histidine kinase activity
CXF51_02470	COG0840	transmembrane signaling receptor activity
CXF51_02475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CXF51_02480	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CXF51_02505	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CXF51_02520	COG0697	spore germination
CXF51_02530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXF51_02550	COG1126	abc transporter atp-binding protein
CXF51_02560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXF51_02565	COG0583	DNA-binding transcription factor activity
CXF51_02575	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CXF51_02590	COG0596	Alpha beta hydrolase
CXF51_02600	COG5434	Belongs to the glycosyl hydrolase 28 family
CXF51_02625	COG1136	(ABC) transporter
CXF51_02630	COG0577	efflux transmembrane transporter activity
CXF51_02670	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXF51_02680	COG4604	ABC transporter, ATP-binding protein
CXF51_02685	COG4607	ABC-type enterochelin transport system periplasmic component
CXF51_02690	COG2814	Major facilitator Superfamily
CXF51_02695	COG1309	transcriptional regulator
CXF51_02700	COG0778	Nitroreductase
CXF51_02705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXF51_02710	COG0640	Transcriptional regulator
CXF51_02730	COG4975	Glucose uptake
CXF51_02740	COG4549	nuclear export factor GLE1
CXF51_02760	COG2213	PTS system mannitol-specific
CXF51_02800	COG0561	phosphatase activity
CXF51_02805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CXF51_02815	COG4336	lyase activity
CXF51_02825	COG1984	allophanate hydrolase subunit 2
CXF51_02835	COG2755	lipolytic protein G-D-S-L family
CXF51_02845	COG2329	Antibiotic biosynthesis monooxygenase
CXF51_02850	COG0768	penicillin binding
CXF51_02870	COG2226	methyltransferase
CXF51_02875	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_02885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXF51_02900	COG2814	Major facilitator Superfamily
CXF51_02920	COG3706	GGDEF domain
CXF51_02940	COG0531	amino acid
CXF51_02945	COG0494	nUDIX hydrolase
CXF51_02950	COG0028	Belongs to the TPP enzyme family
CXF51_02965	COG1914	H( )-stimulated, divalent metal cation uptake system
CXF51_02970	COG2261	transglycosylase associated protein
CXF51_02975	COG4876	unkown
CXF51_02980	COG2217	Heavy metal translocating P-type atpase
CXF51_02985	COG3729	General stress protein
CXF51_02990	COG0662	Cupin 2, conserved barrel domain protein
CXF51_03000	COG3546	catalase activity
CXF51_03005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CXF51_03010	COG3290	protein histidine kinase activity
CXF51_03015	COG4565	transcriptional regulatory protein
CXF51_03020	COG1301	dicarboxylic acid transport
CXF51_03060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXF51_03065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_03070	COG1181	Belongs to the D-alanine--D-alanine ligase family
CXF51_03085	COG0513	Belongs to the DEAD box helicase family
CXF51_03095	COG3428	Bacterial PH domain
CXF51_03100	COG0705	Rhomboid family
CXF51_03105	COG0736	holo-[acyl-carrier-protein] synthase activity
CXF51_03115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CXF51_03120	COG0864	Transcriptional regulator
CXF51_03125	COG2337	Toxic component of a toxin-antitoxin (TA) module
CXF51_03135	COG1366	Belongs to the anti-sigma-factor antagonist family
CXF51_03140	COG2172	sigma factor antagonist activity
CXF51_03145	COG2208	phosphoserine phosphatase activity
CXF51_03150	COG1366	Belongs to the anti-sigma-factor antagonist family
CXF51_03155	COG2172	sigma factor antagonist activity
CXF51_03160	COG1191	sigma factor activity
CXF51_03165	COG2208	phosphoserine phosphatase activity
CXF51_03170	COG2183	response to ionizing radiation
CXF51_03180	COG3091	SprT-like family
CXF51_03235	COG1476	TRANSCRIPTIONal
CXF51_03250	COG1278	Cold shock
CXF51_03255	COG1329	Transcriptional regulator
CXF51_03285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXF51_03290	COG0477	Major facilitator Superfamily
CXF51_03315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXF51_03330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CXF51_03335	COG2030	dehydratase
CXF51_03340	COG3545	Serine hydrolase
CXF51_03355	COG1733	regulation of RNA biosynthetic process
CXF51_03360	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXF51_03365	COG2814	Major facilitator Superfamily
CXF51_03370	COG1309	transcriptional regulator
CXF51_03375	COG0640	Transcriptional regulator
CXF51_03380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CXF51_03390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXF51_03395	COG0697	spore germination
CXF51_03405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXF51_03410	COG0640	Transcriptional regulator
CXF51_03430	COG4585	Histidine kinase
CXF51_03445	COG0596	Alpha beta hydrolase
CXF51_03455	COG0789	Transcriptional regulator
CXF51_03455	COG4978	Transcriptional regulator
CXF51_03460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXF51_03470	COG0346	lactoylglutathione lyase activity
CXF51_03475	COG2259	Doxx family
CXF51_03480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_03505	COG0071	Belongs to the small heat shock protein (HSP20) family
CXF51_03530	COG0456	acetyltransferase
CXF51_03540	COG1113	amino acid transport
CXF51_03545	COG2318	DinB family
CXF51_03550	COG1846	Transcriptional regulator
CXF51_03560	COG0778	Nitroreductase
CXF51_03565	COG1846	Transcriptional regulator
CXF51_03575	COG0730	response to heat
CXF51_03580	COG1802	Transcriptional regulator
CXF51_03585	COG3858	chitin binding
CXF51_03585	COG1388	LysM domain
CXF51_03590	COG1819	glycosyl
CXF51_03605	COG5646	InterPro IPR014922
CXF51_03615	COG0454	-acetyltransferase
CXF51_03620	COG1078	dGTPase activity
CXF51_03625	COG1388	LysM domain
CXF51_03630	COG2814	Major facilitator Superfamily
CXF51_03635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXF51_03640	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXF51_03650	COG2723	6-phospho-beta-galactosidase activity
CXF51_03655	COG2188	Transcriptional regulator
CXF51_03660	COG1940	carbohydrate kinase activity
CXF51_03665	COG1482	cell wall glycoprotein biosynthetic process
CXF51_03670	COG4124	Belongs to the glycosyl hydrolase 26 family
CXF51_03715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CXF51_03720	COG0802	atpase or kinase
CXF51_03730	COG0456	acetyltransferase
CXF51_03735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CXF51_03745	COG0315	cyclic pyranopterin monophosphate synthase activity
CXF51_03755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXF51_03775	COG1266	CAAX protease self-immunity
CXF51_03780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CXF51_03785	COG0459	protein refolding
CXF51_03795	COG2856	Zn peptidase
CXF51_03810	COG1396	sequence-specific DNA binding
CXF51_03850	COG5377	YqaJ viral recombinase family
CXF51_03855	COG3723	Recombinational DNA repair protein, rece pathway
CXF51_03860	COG3935	DnaD domain protein
CXF51_03865	COG1484	DNA-dependent DNA replication
CXF51_03945	COG3677	Transposase
CXF51_04090	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXF51_04090	COG3409	Peptidoglycan-binding domain 1 protein
CXF51_04115	COG1073	alpha beta
CXF51_04125	COG1063	alcohol dehydrogenase
CXF51_04140	COG1842	Phage shock protein A
CXF51_04150	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CXF51_04175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CXF51_04195	COG2267	carboxylic ester hydrolase activity
CXF51_04220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CXF51_04225	COG0714	Associated with various cellular activities
CXF51_04240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CXF51_04240	COG0519	Catalyzes the synthesis of GMP from XMP
CXF51_04255	COG2252	PERMEase
CXF51_04260	COG3064	Membrane
CXF51_04270	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CXF51_04280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CXF51_04285	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CXF51_04290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CXF51_04295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CXF51_04300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CXF51_04305	COG0047	phosphoribosylformylglycinamidine synthase activity
CXF51_04320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CXF51_04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CXF51_04330	COG0138	bifunctional purine biosynthesis protein purh
CXF51_04335	COG0151	Belongs to the GarS family
CXF51_04340	COG1522	sequence-specific DNA binding
CXF51_04365	COG4496	protein, YerC YecD
CXF51_04395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXF51_04410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CXF51_04420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CXF51_04425	COG1309	transcriptional regulator
CXF51_04435	COG1597	lipid kinase activity
CXF51_04440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXF51_04500	COG5444	nuclease activity
CXF51_04510	COG3586	endonuclease activity
CXF51_04535	COG0217	transcriptional regulatory protein
CXF51_04550	COG3631	Ketosteroid isomerase-related protein
CXF51_04555	COG0702	epimerase
CXF51_04570	COG3546	catalase activity
CXF51_04575	COG0454	-acetyltransferase
CXF51_04590	COG2972	Histidine kinase
CXF51_04640	COG3401	FG-GAP repeat protein
CXF51_04645	COG3401	FG-GAP repeat protein
CXF51_04665	COG1653	transport
CXF51_04675	COG0395	ABC-type sugar transport system, permease component
CXF51_04690	COG2329	Antibiotic biosynthesis monooxygenase
CXF51_04695	COG0346	lactoylglutathione lyase activity
CXF51_04710	COG5583	Uncharacterized small protein (DUF2292)
CXF51_04715	COG0670	Belongs to the BI1 family
CXF51_04720	COG0697	spore germination
CXF51_04730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CXF51_04750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CXF51_04750	COG2124	cytochrome p450
CXF51_04785	COG1442	glycosyl transferase family 8
CXF51_04795	COG1011	Hydrolase
CXF51_04810	COG0840	transmembrane signaling receptor activity
CXF51_04825	COG0789	Transcriptional regulator
CXF51_04850	COG0456	acetyltransferase
CXF51_04865	COG1120	ATPase activity
CXF51_04870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXF51_04880	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CXF51_04900	COG3866	Pectate lyase
CXF51_04930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXF51_04940	COG1254	Belongs to the acylphosphatase family
CXF51_04970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXF51_04970	COG1263	PTS System
CXF51_04990	COG1115	amino acid carrier protein
CXF51_04995	COG0531	amino acid
CXF51_05020	COG0366	Alpha amylase catalytic
CXF51_05025	COG2188	Transcriptional regulator
CXF51_05040	COG0693	protein deglycase activity
CXF51_05045	COG2814	Major facilitator Superfamily
CXF51_05060	COG4980	gas vesicle protein
CXF51_05070	COG0477	Major facilitator Superfamily
CXF51_05075	COG0387	Pfam Sodium calcium exchanger
CXF51_05085	COG0668	transmembrane transport
CXF51_05090	COG0535	radical SAM domain protein
CXF51_05100	COG0726	polysaccharide deacetylase
CXF51_05105	COG2084	Dehydrogenase
CXF51_05110	COG0598	Magnesium transport protein CorA
CXF51_05120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CXF51_05150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXF51_05155	COG0022	dehydrogenase e1 component
CXF51_05180	COG1742	UPF0060 membrane protein
CXF51_05205	COG4842	Belongs to the WXG100 family
CXF51_05210	COG1486	melibiose metabolic process
CXF51_05215	COG1737	Transcriptional regulator
CXF51_05230	COG1132	(ABC) transporter
CXF51_05235	COG2259	Doxx family
CXF51_05240	COG2514	catechol 2,3-dioxygenase activity
CXF51_05245	COG4585	Histidine kinase
CXF51_05250	COG2197	response regulator
CXF51_05255	COG1131	(ABC) transporter
CXF51_05265	COG0842	Transport permease protein
CXF51_05270	COG1695	Transcriptional regulator
CXF51_05285	COG1309	transcriptional regulator
CXF51_05295	COG2318	DinB family
CXF51_05305	COG1846	Transcriptional regulator
CXF51_05315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXF51_05320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXF51_05325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CXF51_05335	COG0778	Nitroreductase
CXF51_05380	COG3103	Sh3 type 3 domain protein
CXF51_05385	COG5658	integral membrane protein
CXF51_05390	COG0596	Alpha beta hydrolase
CXF51_05395	COG0463	Glycosyl transferase, family 2
CXF51_05410	COG1194	a g-specific adenine glycosylase
CXF51_05435	COG3557	Belongs to the UPF0374 family
CXF51_05450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CXF51_05455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CXF51_05460	COG0735	belongs to the Fur family
CXF51_05570	COG4326	sporulation control protein
CXF51_05580	COG5577	PFAM Coat F domain
CXF51_05585	COG3340	Belongs to the peptidase S51 family
CXF51_05590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CXF51_05620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CXF51_05635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CXF51_05645	COG1476	TRANSCRIPTIONal
CXF51_05670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CXF51_05675	COG0789	Transcriptional regulator
CXF51_05685	COG1664	Polymer-forming cytoskeletal
CXF51_05690	COG2766	serine protein kinase
CXF51_05705	COG1566	PFAM secretion protein HlyD family protein
CXF51_05710	COG2814	Major facilitator Superfamily
CXF51_05715	COG0655	NAD(P)H dehydrogenase (quinone) activity
CXF51_05735	COG1725	Transcriptional regulator
CXF51_05740	COG1131	(ABC) transporter
CXF51_05745	COG1131	(ABC) transporter
CXF51_05750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CXF51_05755	COG1278	Cold shock
CXF51_05765	COG1464	Belongs to the NlpA lipoprotein family
CXF51_05800	COG5577	PFAM Coat F domain
CXF51_05810	COG3764	Sortase (surface protein transpeptidase)
CXF51_05815	COG0564	pseudouridine synthase activity
CXF51_05825	COG0517	IMP dehydrogenase activity
CXF51_05830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CXF51_05850	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CXF51_05855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CXF51_05860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CXF51_05875	COG4585	Histidine kinase
CXF51_05875	COG2203	Gaf domain
CXF51_05880	COG2197	response regulator
CXF51_05900	COG1388	LysM domain
CXF51_05900	COG0791	NLP P60 protein
CXF51_05905	COG1959	2 iron, 2 sulfur cluster binding
CXF51_05910	COG0668	transmembrane transport
CXF51_05915	COG2719	SpoVR family
CXF51_05920	COG1785	Belongs to the alkaline phosphatase family
CXF51_05925	COG1388	LysM domain
CXF51_05925	COG0791	NLP P60 protein
CXF51_05930	COG0583	DNA-binding transcription factor activity
CXF51_05935	COG0372	Belongs to the citrate synthase family
CXF51_05940	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_05950	COG0733	neurotransmitter:sodium symporter activity
CXF51_05960	COG0456	acetyltransferase
CXF51_05975	COG1595	DNA-templated transcription, initiation
CXF51_05990	COG1253	flavin adenine dinucleotide binding
CXF51_05995	COG0789	Transcriptional regulator
CXF51_06000	COG0436	Aminotransferase
CXF51_06005	COG1253	flavin adenine dinucleotide binding
CXF51_06010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXF51_06015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CXF51_06020	COG0584	glycerophosphoryl diester phosphodiesterase
CXF51_06035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CXF51_06040	COG0726	polysaccharide deacetylase
CXF51_06045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CXF51_06055	COG0589	response to stress
CXF51_06065	COG1132	(ABC) transporter
CXF51_06075	COG0702	epimerase
CXF51_06110	COG3679	Belongs to the UPF0342 family
CXF51_06130	COG0475	glutathione-regulated potassium exporter activity
CXF51_06135	COG0490	domain, Protein
CXF51_06160	COG1668	transmembrane transport
CXF51_06175	COG3481	metal-dependent phosphohydrolase, HD sub domain
CXF51_06215	COG1846	Transcriptional regulator
CXF51_06235	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CXF51_06240	COG0537	adenosine 5'-monophosphoramidase activity
CXF51_06245	COG1131	(ABC) transporter
CXF51_06265	COG3069	C4-dicarboxylate transmembrane transporter activity
CXF51_06275	COG2329	Antibiotic biosynthesis monooxygenase
CXF51_06310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXF51_06325	COG1363	Peptidase, m42
CXF51_06330	COG4405	Protein conserved in bacteria
CXF51_06335	COG1301	dicarboxylic acid transport
CXF51_06345	COG1234	tRNA 3'-trailer cleavage
CXF51_06355	COG0702	epimerase
CXF51_06380	COG0456	acetyltransferase
CXF51_06390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CXF51_06395	COG0406	alpha-ribazole phosphatase activity
CXF51_06400	COG0183	Belongs to the thiolase family
CXF51_06405	COG0318	PFAM AMP-dependent synthetase and ligase
CXF51_06415	COG0840	transmembrane signaling receptor activity
CXF51_06435	COG4903	ComK protein
CXF51_06440	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_06450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXF51_06465	COG0398	Pfam SNARE associated Golgi protein
CXF51_06480	COG1846	Transcriptional regulator
CXF51_06515	COG0477	Major facilitator Superfamily
CXF51_06515	COG2814	Major facilitator Superfamily
CXF51_06530	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CXF51_06545	COG0420	3'-5' exonuclease activity
CXF51_06555	COG1403	HNH endonuclease
CXF51_06625	COG2318	DinB family
CXF51_06635	COG0534	Mate efflux family protein
CXF51_06640	COG1917	Cupin 2, conserved barrel domain protein
CXF51_06640	COG2207	Transcriptional regulator
CXF51_06655	COG2318	DinB family
CXF51_06660	COG1279	arginine transmembrane transporter activity
CXF51_06670	COG1357	PFAM Pentapeptide repeats (8 copies)
CXF51_06680	COG0529	Catalyzes the synthesis of activated sulfate
CXF51_06690	COG0175	sulfate reduction
CXF51_06695	COG2045	Belongs to the ComB family
CXF51_06710	COG4948	Mandelate Racemase Muconate Lactonizing
CXF51_06740	COG2996	Protein conserved in bacteria
CXF51_06760	COG1695	Transcriptional regulator
CXF51_06775	COG3227	Zinc metalloprotease (Elastase)
CXF51_06785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXF51_06800	COG0561	phosphatase activity
CXF51_06805	COG1073	alpha beta
CXF51_06810	COG2151	metal-sulfur cluster biosynthetic enzyme
CXF51_06825	COG2271	Major facilitator Superfamily
CXF51_06860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CXF51_06875	COG2267	carboxylic ester hydrolase activity
CXF51_06900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CXF51_06915	COG0444	Belongs to the ABC transporter superfamily
CXF51_06920	COG4608	Belongs to the ABC transporter superfamily
CXF51_06935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXF51_06960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CXF51_06965	COG0444	Belongs to the ABC transporter superfamily
CXF51_06970	COG4608	Belongs to the ABC transporter superfamily
CXF51_06985	COG1393	Belongs to the ArsC family
CXF51_06990	COG0861	Integral membrane protein TerC family
CXF51_07005	COG1164	Oligoendopeptidase f
CXF51_07030	COG2346	COG2346, Truncated hemoglobins
CXF51_07040	COG4116	CYTH
CXF51_07050	COG2357	RelA SpoT domain protein
CXF51_07055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXF51_07065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CXF51_07075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CXF51_07080	COG0352	thiamine-phosphate diphosphorylase activity
CXF51_07085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CXF51_07090	COG2104	thiamine diphosphate biosynthetic process
CXF51_07095	COG2022	thiamine diphosphate biosynthetic process
CXF51_07100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CXF51_07105	COG0351	phosphomethylpyrimidine kinase
CXF51_07110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CXF51_07175	COG2153	protein acetylation
CXF51_07180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXF51_07185	COG2382	esterase
CXF51_07190	COG0626	cystathionine gamma-synthase activity
CXF51_07195	COG0626	cystathionine gamma-synthase activity
CXF51_07200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXF51_07325	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CXF51_07350	COG1482	cell wall glycoprotein biosynthetic process
CXF51_07370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CXF51_07415	COG5504	Zn-dependent protease
CXF51_07420	COG2205	protein histidine kinase activity
CXF51_07430	COG3383	formate dehydrogenase (NAD+) activity
CXF51_07475	COG0390	transport system, permease component
CXF51_07480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXF51_07485	COG0697	spore germination
CXF51_07490	COG4297	protein containing double-stranded beta helix domain
CXF51_07500	COG1252	NADH dehydrogenase
CXF51_07505	COG1904	glucuronate isomerase
CXF51_07525	COG1312	Catalyzes the dehydration of D-mannonate
CXF51_07530	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_07555	COG0730	response to heat
CXF51_07560	COG2318	DinB family
CXF51_07580	COG2350	Protein conserved in bacteria
CXF51_07585	COG3409	Peptidoglycan-binding domain 1 protein
CXF51_07585	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXF51_07585	COG1388	LysM domain
CXF51_07595	COG4195	phage-related replication protein
CXF51_07605	COG2856	Zn peptidase
CXF51_07610	COG1396	sequence-specific DNA binding
CXF51_07615	COG1522	sequence-specific DNA binding
CXF51_07620	COG1484	DNA-dependent DNA replication
CXF51_07660	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CXF51_07665	COG4653	Phage capsid family
CXF51_07740	COG3299	homolog of phage Mu protein gp47
CXF51_07745	COG3778	Protein conserved in bacteria
CXF51_07800	COG0306	phosphate transporter
CXF51_07805	COG1392	Phosphate transport regulator
CXF51_07845	COG2362	D-Aminopeptidase
CXF51_07870	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXF51_07885	COG4608	Belongs to the ABC transporter superfamily
CXF51_07900	COG1607	acyl-coa hydrolase
CXF51_07905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CXF51_07905	COG1017	nitric oxide dioxygenase activity
CXF51_07915	COG2323	membrane
CXF51_07920	COG2318	DinB family
CXF51_07925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXF51_07935	COG2076	Multidrug Resistance protein
CXF51_07940	COG0788	formyltetrahydrofolate deformylase activity
CXF51_07945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CXF51_07950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CXF51_07955	COG1764	response to oxidative stress
CXF51_07960	COG1846	Transcriptional regulator
CXF51_07965	COG1764	response to oxidative stress
CXF51_07970	COG0590	tRNA wobble adenosine to inosine editing
CXF51_07980	COG1404	Belongs to the peptidase S8 family
CXF51_07985	COG1366	Belongs to the anti-sigma-factor antagonist family
CXF51_07990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CXF51_08000	COG4721	ABC-type cobalt transport system, permease component
CXF51_08015	COG3850	Histidine kinase
CXF51_08015	COG5002	protein histidine kinase activity
CXF51_08025	COG3212	peptidase
CXF51_08040	COG2239	Acts as a magnesium transporter
CXF51_08060	COG1846	Transcriptional regulator
CXF51_08070	COG0726	polysaccharide deacetylase
CXF51_08075	COG1408	metallophosphoesterase
CXF51_08085	COG0463	Glycosyl transferase, family 2
CXF51_08105	COG0586	Pfam SNARE associated Golgi protein
CXF51_08115	COG1191	sigma factor activity
CXF51_08135	COG0501	Belongs to the peptidase M48B family
CXF51_08155	COG3594	Acyltransferase
CXF51_08165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CXF51_08170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CXF51_08175	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CXF51_08185	COG0436	Aminotransferase
CXF51_08200	COG0235	Class ii aldolase
CXF51_08230	COG1846	Transcriptional regulator
CXF51_08235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CXF51_08255	COG0720	synthase
CXF51_08265	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CXF51_08275	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_08285	COG1388	LysM domain
CXF51_08295	COG3858	chitin binding
CXF51_08305	COG4873	Protein conserved in bacteria
CXF51_08325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_08330	COG2217	Heavy metal translocating P-type atpase
CXF51_08345	COG1609	Transcriptional regulator
CXF51_08350	COG3711	transcriptional antiterminator
CXF51_08360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXF51_08365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CXF51_08390	COG2084	Dehydrogenase
CXF51_08395	COG2340	Cysteine-rich secretory protein family
CXF51_08420	COG0784	Response regulator, receiver
CXF51_08420	COG0835	chemotaxis
CXF51_08435	COG1376	ErfK ybiS ycfS ynhG family protein
CXF51_08455	COG4703	Protein of unknown function (DUF1797)
CXF51_08475	COG0583	DNA-binding transcription factor activity
CXF51_08490	COG0716	FMN binding
CXF51_08495	COG2171	N-acyltransferase activity
CXF51_08500	COG1473	amidohydrolase
CXF51_08515	COG0450	alkyl hydroperoxide reductase
CXF51_08520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_08535	COG0746	molybdenum cofactor guanylyltransferase activity
CXF51_08545	COG0303	'Molybdopterin
CXF51_08550	COG1763	Mo-molybdopterin cofactor biosynthetic process
CXF51_08555	COG0314	molybdopterin synthase activity
CXF51_08560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CXF51_08580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXF51_08585	COG1136	(ABC) transporter
CXF51_08595	COG1349	DNA-binding transcription factor activity
CXF51_08625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CXF51_08630	COG2309	aminopeptidase activity
CXF51_08645	COG2002	toxin-antitoxin pair type II binding
CXF51_08660	COG0569	domain protein
CXF51_08670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CXF51_08685	COG0242	peptide deformylase activity
CXF51_08705	COG0022	dehydrogenase e1 component
CXF51_08720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_08735	COG4476	Belongs to the UPF0223 family
CXF51_08835	COG4838	Belongs to the UPF0358 family
CXF51_08855	COG0109	protoheme IX farnesyltransferase activity
CXF51_08860	COG2010	Cytochrome c
CXF51_08860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CXF51_08870	COG1845	cytochrome c oxidase, subunit III
CXF51_08890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CXF51_08915	COG3679	Belongs to the UPF0342 family
CXF51_08920	COG4471	UPF0298 protein
CXF51_08925	COG0742	ribosomal rna small subunit methyltransferase
CXF51_08940	COG1752	Esterase of the alpha-beta hydrolase superfamily
CXF51_08945	COG3480	Lon protease (S16) C-terminal proteolytic domain
CXF51_08960	COG1399	metal-binding, possibly nucleic acid-binding protein
CXF51_08965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CXF51_08975	COG0454	-acetyltransferase
CXF51_08990	COG2001	Belongs to the MraZ family
CXF51_08995	COG0275	rRNA processing
CXF51_09000	COG4839	cell division protein FtsL
CXF51_09015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CXF51_09025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CXF51_09050	COG3879	Bacterial protein of unknown function (DUF881)
CXF51_09055	COG3879	Bacterial protein of unknown function (DUF881)
CXF51_09060	COG3856	small basic protein
CXF51_09070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CXF51_09090	COG1191	sigma factor activity
CXF51_09105	COG1873	PFAM PRC-barrel domain
CXF51_09115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CXF51_09125	COG0762	integral membrane protein
CXF51_09140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CXF51_09145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXF51_09150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CXF51_09155	COG0564	pseudouridine synthase activity
CXF51_09160	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CXF51_09165	COG2233	PERMEase
CXF51_09170	COG0540	Belongs to the ATCase OTCase family
CXF51_09175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CXF51_09180	COG0505	Belongs to the CarA family
CXF51_09190	COG0543	2 iron, 2 sulfur cluster binding
CXF51_09200	COG0284	orotidine-5'-phosphate decarboxylase activity
CXF51_09205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CXF51_09210	COG0175	sulfate reduction
CXF51_09225	COG0529	Catalyzes the synthesis of activated sulfate
CXF51_09235	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CXF51_09255	COG1561	YicC-like family, N-terminal region
CXF51_09260	COG2052	Domain of unknown function (DUF370)
CXF51_09265	COG0194	GDP metabolic process
CXF51_09270	COG1758	RNA polymerase activity
CXF51_09275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CXF51_09280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CXF51_09285	COG0242	peptide deformylase activity
CXF51_09290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CXF51_09300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CXF51_09315	COG1162	GTPase activity
CXF51_09320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CXF51_09325	COG1564	THIamine pyrophosphokinase
CXF51_09335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CXF51_09340	COG1302	Protein conserved in bacteria
CXF51_09345	COG1461	Dihydroxyacetone kinase
CXF51_09350	COG1760	l-serine dehydratase
CXF51_09355	COG1760	l-serine dehydratase
CXF51_09360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CXF51_09365	COG1349	DNA-binding transcription factor activity
CXF51_09365	COG2050	protein possibly involved in aromatic compounds catabolism
CXF51_09375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXF51_09380	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_09385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXF51_09400	COG0552	protein localization to endoplasmic reticulum
CXF51_09410	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CXF51_09415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CXF51_09425	COG1837	Belongs to the UPF0109 family
CXF51_09435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CXF51_09440	COG0336	Belongs to the RNA methyltransferase TrmD family
CXF51_09445	COG0335	large ribosomal subunit rRNA binding
CXF51_09450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CXF51_09470	COG0045	succinate-CoA ligase (ADP-forming) activity
CXF51_09480	COG0758	DNA mediated transformation
CXF51_09500	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CXF51_09505	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CXF51_09515	COG1815	bacterial-type flagellum-dependent cell motility
CXF51_09520	COG1558	bacterial-type flagellum-dependent cell motility
CXF51_09525	COG1677	Flagellar hook-basal body complex protein FliE
CXF51_09530	COG1766	The M ring may be actively involved in energy transduction
CXF51_09535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXF51_09545	COG1157	protein secretion by the type III secretion system
CXF51_09550	COG2882	bacterial-type flagellum organization
CXF51_09555	COG3334	PFAM MgtE intracellular
CXF51_09560	COG3144	bacterial-type flagellum assembly
CXF51_09565	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CXF51_09570	COG4786	Flagellar basal body rod
CXF51_09575	COG1582	Flagellar protein (FlbD)
CXF51_09580	COG1580	Controls the rotational direction of flagella during chemotaxis
CXF51_09585	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXF51_09590	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CXF51_09590	COG1776	CheC inhibitor of MCP methylation
CXF51_09595	COG2201	protein-glutamate methylesterase activity
CXF51_09600	COG3190	flagellar
CXF51_09610	COG1987	bacterial-type flagellum assembly
CXF51_09615	COG1684	flagellar biosynthetic protein fliR
CXF51_09635	COG0455	bacterial-type flagellum organization
CXF51_09640	COG2201	protein-glutamate methylesterase activity
CXF51_09645	COG0643	Histidine kinase
CXF51_09645	COG2198	Histidine kinase
CXF51_09650	COG0835	chemotaxis
CXF51_09655	COG1776	CheC inhibitor of MCP methylation
CXF51_09660	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CXF51_09665	COG1191	sigma factor activity
CXF51_09675	COG0052	Belongs to the universal ribosomal protein uS2 family
CXF51_09685	COG0528	UMP kinase activity
CXF51_09695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CXF51_09705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CXF51_09715	COG0442	prolyl-tRNA aminoacylation
CXF51_09730	COG0195	Participates in both transcription termination and antitermination
CXF51_09735	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CXF51_09740	COG1358	cellular component organization or biogenesis
CXF51_09750	COG1550	Protein conserved in bacteria
CXF51_09755	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CXF51_09770	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CXF51_09790	COG1873	PFAM PRC-barrel domain
CXF51_09810	COG0527	aspartate kinase activity
CXF51_09820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CXF51_09825	COG0740	serine-type endopeptidase activity
CXF51_09835	COG4980	gas vesicle protein
CXF51_09835	COG1674	ftsk spoiiie
CXF51_09850	COG0612	Peptidase, M16
CXF51_09855	COG0612	Peptidase, M16
CXF51_09860	COG0300	oxidoreductase activity
CXF51_09875	COG1426	Protein conserved in bacteria
CXF51_09880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CXF51_09890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CXF51_09895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CXF51_09910	COG2359	stage V sporulation protein S
CXF51_09915	COG1063	alcohol dehydrogenase
CXF51_09930	COG4550	Control of competence regulator ComK, YlbF/YmcA
CXF51_09945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CXF51_09960	COG3226	Transcriptional regulator
CXF51_09965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXF51_09975	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXF51_09985	COG2070	2-Nitropropane dioxygenase
CXF51_09985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CXF51_09990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXF51_09995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CXF51_10005	COG1024	Enoyl-CoA hydratase
CXF51_10040	COG2124	cytochrome p450
CXF51_10050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXF51_10075	COG2076	Multidrug Resistance protein
CXF51_10095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CXF51_10100	COG1923	regulation of RNA biosynthetic process
CXF51_10115	COG1780	Probably involved in ribonucleotide reductase function
CXF51_10125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXF51_10130	COG4112	unkown
CXF51_10135	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXF51_10170	COG4282	regulation of fungal-type cell wall biogenesis
CXF51_10235	COG0457	Tetratricopeptide repeat
CXF51_10310	COG0582	viral genome integration into host DNA
CXF51_10495	COG3655	Transcriptional regulator
CXF51_10570	COG0582	viral genome integration into host DNA
CXF51_10625	COG3645	SOS response
CXF51_10625	COG3646	Phage regulatory protein
CXF51_10705	COG1793	dna ligase
CXF51_10710	COG2135	peptidase activity
CXF51_10765	COG2887	Belongs to the helicase family. UvrD subfamily
CXF51_10820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CXF51_10945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CXF51_10950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_10960	COG0756	dUTP diphosphatase activity
CXF51_10990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXF51_11010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CXF51_11050	COG3331	DNA recombination
CXF51_11070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CXF51_11075	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CXF51_11080	COG0789	Transcriptional regulator
CXF51_11085	COG0174	glutamine synthetase
CXF51_11160	COG3655	Transcriptional regulator
CXF51_11185	COG3507	Belongs to the glycosyl hydrolase 43 family
CXF51_11195	COG2115	Belongs to the xylose isomerase family
CXF51_11210	COG1525	nuclease
CXF51_11215	COG2814	Major facilitator Superfamily
CXF51_11230	COG0756	dUTP diphosphatase activity
CXF51_11275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CXF51_11285	COG3832	glyoxalase III activity
CXF51_11300	COG0697	spore germination
CXF51_11305	COG0531	amino acid
CXF51_11340	COG0346	lactoylglutathione lyase activity
CXF51_11350	COG1388	LysM domain
CXF51_11360	COG4224	UPF0291 protein
CXF51_11385	COG0785	Cytochrome C biogenesis protein
CXF51_11390	COG2201	protein-glutamate methylesterase activity
CXF51_11425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_11455	COG4841	protein insertion into membrane
CXF51_11460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CXF51_11465	COG1832	CoA-binding protein
CXF51_11485	COG1115	amino acid carrier protein
CXF51_11500	COG5520	Belongs to the glycosyl hydrolase 30 family
CXF51_11510	COG2246	polysaccharide biosynthetic process
CXF51_11515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXF51_11525	COG2404	hydrolase activity, acting on ester bonds
CXF51_11530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CXF51_11555	COG0318	PFAM AMP-dependent synthetase and ligase
CXF51_11580	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CXF51_11580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXF51_11630	COG0582	viral genome integration into host DNA
CXF51_11635	COG0166	Belongs to the GPI family
CXF51_11640	COG0405	Gamma-glutamyltransferase
CXF51_11645	COG0583	DNA-binding transcription factor activity
CXF51_11655	COG0493	'glutamate synthase
CXF51_11665	COG0583	DNA-binding transcription factor activity
CXF51_11675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXF51_11700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CXF51_11715	COG2814	Major facilitator Superfamily
CXF51_11755	COG5278	phosphoserine phosphatase activity
CXF51_11755	COG0840	transmembrane signaling receptor activity
CXF51_11765	COG4305	rare lipoprotein A
CXF51_11770	COG3619	membrane
CXF51_11780	COG2135	peptidase activity
CXF51_11800	COG0456	acetyltransferase
CXF51_11820	COG2720	vancomycin resistance protein
CXF51_11830	COG3655	Transcriptional regulator
CXF51_11840	COG0583	DNA-binding transcription factor activity
CXF51_11855	COG0693	protein deglycase activity
CXF51_11860	COG2367	Beta-lactamase
CXF51_11895	COG2314	TM2 domain
CXF51_11900	COG1396	sequence-specific DNA binding
CXF51_11975	COG1793	dna ligase
CXF51_12015	COG1388	LysM domain
CXF51_12040	COG0457	Tetratricopeptide repeat
CXF51_12050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXF51_12055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXF51_12095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXF51_12100	COG2207	Transcriptional regulator
CXF51_12100	COG0662	Cupin 2, conserved barrel domain protein
CXF51_12105	COG0456	acetyltransferase
CXF51_12120	COG3708	Transcriptional regulator
CXF51_12125	COG2378	regulation of single-species biofilm formation
CXF51_12135	COG0640	Transcriptional regulator
CXF51_12160	COG1619	proteins homologs of microcin C7 resistance protein MccF
CXF51_12165	COG3239	Fatty acid desaturase
CXF51_12175	COG2197	response regulator
CXF51_12185	COG3584	3D domain protein
CXF51_12185	COG1388	LysM domain
CXF51_12190	COG0514	ATP-dependent DNA helicase (RecQ)
CXF51_12210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXF51_12265	COG0733	neurotransmitter:sodium symporter activity
CXF51_12270	COG0385	Bile acid
CXF51_12275	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXF51_12280	COG0567	Dehydrogenase, E1 component
CXF51_12290	COG0714	Associated with various cellular activities
CXF51_12295	COG2032	superoxide dismutase activity
CXF51_12300	COG1388	LysM domain
CXF51_12300	COG0791	NLP P60 protein
CXF51_12325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXF51_12330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CXF51_12360	COG1942	4-Oxalocrotonate Tautomerase
CXF51_12365	COG1733	regulation of RNA biosynthetic process
CXF51_12370	COG0778	Nitroreductase
CXF51_12375	COG0400	carboxylic ester hydrolase activity
CXF51_12380	COG0346	lactoylglutathione lyase activity
CXF51_12390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXF51_12395	COG3409	Peptidoglycan-binding domain 1 protein
CXF51_12395	COG0793	Belongs to the peptidase S41A family
CXF51_12410	COG1876	peptidase activity
CXF51_12430	COG0671	phosphoesterase, PA-phosphatase related
CXF51_12455	COG4479	Belongs to the UPF0346 family
CXF51_12465	COG1509	lysine 2,3-aminomutase activity
CXF51_12470	COG0456	acetyltransferase
CXF51_12485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXF51_12490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CXF51_12520	COG4641	Protein conserved in bacteria
CXF51_12525	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CXF51_12535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXF51_12540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CXF51_12545	COG1846	Transcriptional regulator
CXF51_12550	COG0534	Mate efflux family protein
CXF51_12565	COG2755	lipolytic protein G-D-S-L family
CXF51_12570	COG1999	signal sequence binding
CXF51_12590	COG1272	protein, Hemolysin III
CXF51_12595	COG0204	Acyl-transferase
CXF51_12600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXF51_12605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CXF51_12610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXF51_12620	COG2521	methyltransferase
CXF51_12620	COG2136	Putative SAM-dependent methyltransferase
CXF51_12645	COG0386	Belongs to the glutathione peroxidase family
CXF51_12650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CXF51_12655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CXF51_12660	COG1278	Cold shock
CXF51_12680	COG0328	RNA-DNA hybrid ribonuclease activity
CXF51_12685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CXF51_12700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXF51_12725	COG1755	Isoprenylcysteine carboxyl methyltransferase
CXF51_12730	COG3424	synthase
CXF51_12735	COG2233	PERMEase
CXF51_12760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXF51_12770	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CXF51_12775	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_12780	COG1199	ATP-dependent helicase activity
CXF51_12835	COG0071	Belongs to the small heat shock protein (HSP20) family
CXF51_12870	COG3331	DNA recombination
CXF51_12895	COG0017	Asparaginyl-tRNA synthetase
CXF51_12900	COG0436	Aminotransferase
CXF51_12905	COG5353	protein conserved in bacteria
CXF51_12920	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CXF51_12925	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CXF51_12930	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CXF51_12935	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CXF51_12935	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CXF51_12940	COG0617	tRNA 3'-terminal CCA addition
CXF51_12955	COG1803	Methylglyoxal synthase
CXF51_12960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CXF51_12965	COG1694	Mazg nucleotide pyrophosphohydrolase
CXF51_12980	COG4347	Protein of unknown function (DUF1405)
CXF51_12985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXF51_12985	COG2010	Cytochrome c
CXF51_12990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CXF51_12995	COG0723	plastoquinol--plastocyanin reductase activity
CXF51_13005	COG5582	Belongs to the UPF0302 family
CXF51_13010	COG0457	Tetratricopeptide repeat
CXF51_13015	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CXF51_13020	COG0287	Prephenate dehydrogenase
CXF51_13060	COG4401	Chorismate mutase type I
CXF51_13070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CXF51_13080	COG0105	UTP biosynthetic process
CXF51_13085	COG0142	geranyltranstransferase activity
CXF51_13090	COG2226	methyltransferase
CXF51_13095	COG0142	geranyltranstransferase activity
CXF51_13105	COG0302	gtp cyclohydrolase
CXF51_13110	COG0776	regulation of translation
CXF51_13115	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CXF51_13165	COG0539	negative regulation of cytoplasmic translation
CXF51_13170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CXF51_13185	COG2959	enzyme of heme biosynthesis
CXF51_13195	COG2339	peptidase activity
CXF51_13210	COG4862	establishment of competence for transformation
CXF51_13235	COG0514	ATP-dependent DNA helicase (RecQ)
CXF51_13240	COG4955	Helix-turn-helix domain
CXF51_13245	COG1141	Ferredoxin
CXF51_13260	COG0710	3-dehydroquinate dehydratase activity
CXF51_13270	COG1595	DNA-templated transcription, initiation
CXF51_13300	COG1187	pseudouridine synthase activity
CXF51_13305	COG0700	Nucleoside recognition
CXF51_13330	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CXF51_13335	COG1547	Domain of unknown function (DUF309)
CXF51_13345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CXF51_13355	COG0307	riboflavin synthase, alpha
CXF51_13370	COG0681	Belongs to the peptidase S26 family
CXF51_13380	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CXF51_13405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CXF51_13410	COG4086	secreted protein
CXF51_13415	COG0019	diaminopimelate decarboxylase activity
CXF51_13420	COG0697	spore germination
CXF51_13455	COG1191	sigma factor activity
CXF51_13460	COG2172	sigma factor antagonist activity
CXF51_13465	COG1366	Belongs to the anti-sigma-factor antagonist family
CXF51_13475	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CXF51_13480	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CXF51_13495	COG0735	belongs to the Fur family
CXF51_13500	COG1300	Membrane
CXF51_13510	COG0281	malic enzyme
CXF51_13515	COG1757	Na H antiporter
CXF51_13520	COG1027	Aspartate ammonia-lyase
CXF51_13530	COG1396	sequence-specific DNA binding
CXF51_13570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CXF51_13570	COG0456	acetyltransferase
CXF51_13575	COG2329	Antibiotic biosynthesis monooxygenase
CXF51_13590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CXF51_13610	COG0346	lactoylglutathione lyase activity
CXF51_13630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXF51_13635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CXF51_13645	COG1902	pentaerythritol trinitrate reductase activity
CXF51_13650	COG0596	Alpha beta hydrolase
CXF51_13660	COG1234	tRNA 3'-trailer cleavage
CXF51_13665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CXF51_13670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CXF51_13685	COG0706	membrane insertase activity
CXF51_13715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXF51_13730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXF51_13735	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_13750	COG0109	protoheme IX farnesyltransferase activity
CXF51_13755	COG3361	conserved protein (COG2071)
CXF51_13760	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXF51_13770	COG0346	lactoylglutathione lyase activity
CXF51_13775	COG1376	ErfK ybiS ycfS ynhG family protein
CXF51_13780	COG4129	membrane
CXF51_13790	COG0765	amino acid transport
CXF51_13805	COG1597	lipid kinase activity
CXF51_13815	COG4978	Transcriptional regulator
CXF51_13815	COG0789	Transcriptional regulator
CXF51_13820	COG0508	dehydrogenase complex catalyzes the overall conversion of
CXF51_13830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CXF51_13845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CXF51_13850	COG0280	phosphate acetyltransferase
CXF51_13865	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CXF51_13885	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXF51_13900	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXF51_13910	COG1902	pentaerythritol trinitrate reductase activity
CXF51_13915	COG0745	RESPONSE REGULATOR receiver
CXF51_13930	COG1438	arginine binding
CXF51_13940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CXF51_13945	COG0142	geranyltranstransferase activity
CXF51_13950	COG1722	exodeoxyribonuclease VII activity
CXF51_13960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CXF51_13965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CXF51_13970	COG1302	Protein conserved in bacteria
CXF51_13980	COG0511	ligase activity, forming carbon-carbon bonds
CXF51_14030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CXF51_14035	COG0006	proline dipeptidase activity
CXF51_14040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CXF51_14050	COG3872	metal-dependent enzyme
CXF51_14070	COG0095	Lipoate-protein ligase
CXF51_14075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXF51_14080	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CXF51_14110	COG1396	sequence-specific DNA binding
CXF51_14155	COG4970	Tfp pilus assembly protein FimT
CXF51_14170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CXF51_14175	COG0517	IMP dehydrogenase activity
CXF51_14185	COG1253	flavin adenine dinucleotide binding
CXF51_14190	COG1366	Belongs to the anti-sigma-factor antagonist family
CXF51_14200	COG1393	Belongs to the ArsC family
CXF51_14220	COG0011	TIGRFAM Protein of
CXF51_14230	COG2866	Carboxypeptidase
CXF51_14240	COG1940	carbohydrate kinase activity
CXF51_14245	COG4483	Protein conserved in bacteria
CXF51_14250	COG0457	Tetratricopeptide repeat
CXF51_14250	COG0705	Rhomboid family
CXF51_14260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CXF51_14265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CXF51_14285	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CXF51_14295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CXF51_14300	COG0581	inorganic phosphate transmembrane transporter activity
CXF51_14305	COG0573	inorganic phosphate transmembrane transporter activity
CXF51_14325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CXF51_14335	COG5521	maltodextrose utilization protein MalA
CXF51_14340	COG1388	LysM domain
CXF51_14345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CXF51_14350	COG4709	membrane
CXF51_14355	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CXF51_14360	COG0735	belongs to the Fur family
CXF51_14365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CXF51_14390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CXF51_14400	COG2384	SAM-dependent methyltransferase
CXF51_14405	COG2010	Cytochrome c
CXF51_14415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CXF51_14425	COG1671	Belongs to the UPF0178 family
CXF51_14435	COG0517	IMP dehydrogenase activity
CXF51_14440	COG0751	glycine-tRNA ligase activity
CXF51_14460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CXF51_14465	COG0295	cytidine deaminase activity
CXF51_14470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CXF51_14475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CXF51_14485	COG1702	phosphate starvation-inducible protein PhoH
CXF51_14505	COG4864	UPF0365 protein
CXF51_14510	COG1030	water channel activity
CXF51_14520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CXF51_14525	COG1283	sodium-dependent phosphate transmembrane transporter activity
CXF51_14530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CXF51_14535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CXF51_14550	COG0443	Heat shock 70 kDa protein
CXF51_14555	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CXF51_14565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CXF51_14610	COG2131	deaminase
CXF51_14625	COG2226	methyltransferase
CXF51_14630	COG0799	negative regulation of ribosome biogenesis
CXF51_14635	COG1713	HD superfamily hydrolase involved in NAD metabolism
CXF51_14640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CXF51_14645	COG1534	Rna-binding protein
CXF51_14660	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CXF51_14675	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXF51_14675	COG3409	Peptidoglycan-binding domain 1 protein
CXF51_14680	COG0398	Pfam SNARE associated Golgi protein
CXF51_14685	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CXF51_14695	COG3209	COG3209 Rhs family protein
CXF51_14715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXF51_14725	COG0346	lactoylglutathione lyase activity
CXF51_14730	COG0640	Transcriptional regulator
CXF51_14735	COG3403	YqcI/YcgG family
CXF51_14755	COG5444	nuclease activity
CXF51_14775	COG3409	Peptidoglycan-binding domain 1 protein
CXF51_14775	COG5632	N-Acetylmuramoyl-L-alanine amidase
CXF51_14780	COG4824	toxin secretion phage lysis holin
CXF51_14810	COG3778	Protein conserved in bacteria
CXF51_14815	COG3299	homolog of phage Mu protein gp47
CXF51_14820	COG3628	GPW Gp25 family protein
CXF51_14830	COG4193	domain, Protein
CXF51_14835	COG1652	LysM domain
CXF51_14905	COG4653	Phage capsid family
CXF51_14930	COG1783	phage Terminase large subunit
CXF51_14935	COG5484	DNA packaging
CXF51_14945	COG3677	Transposase
CXF51_14970	COG1484	DNA-dependent DNA replication
CXF51_14975	COG3935	DnaD domain protein
CXF51_14985	COG5377	YqaJ viral recombinase family
CXF51_15015	COG3620	sequence-specific DNA binding
CXF51_15025	COG0563	adenylate kinase activity
CXF51_15030	COG2856	Zn peptidase
CXF51_15045	COG0534	Mate efflux family protein
CXF51_15055	COG0730	response to heat
CXF51_15060	COG0425	Belongs to the sulfur carrier protein TusA family
CXF51_15065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CXF51_15065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXF51_15085	COG2210	Belongs to the sulfur carrier protein TusA family
CXF51_15105	COG0662	Cupin 2, conserved barrel domain protein
CXF51_15120	COG0789	Transcriptional regulator
CXF51_15120	COG4978	Transcriptional regulator
CXF51_15125	COG2814	Major facilitator Superfamily
CXF51_15130	COG0456	acetyltransferase
CXF51_15150	COG0583	DNA-binding transcription factor activity
CXF51_15160	COG1230	cation diffusion facilitator family transporter
CXF51_15165	COG1942	4-Oxalocrotonate Tautomerase
CXF51_15170	COG0583	DNA-binding transcription factor activity
CXF51_15185	COG1687	branched-chain amino acid
CXF51_15190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CXF51_15195	COG1522	sequence-specific DNA binding
CXF51_15250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CXF51_15265	COG3443	Belongs to the bacterial solute-binding protein 9 family
CXF51_15270	COG1595	DNA-templated transcription, initiation
CXF51_15290	COG2828	Protein conserved in bacteria
CXF51_15295	COG3409	Peptidoglycan-binding domain 1 protein
CXF51_15305	COG0596	Alpha beta hydrolase
CXF51_15315	COG4991	sh3 domain protein
CXF51_15330	COG5577	PFAM Coat F domain
CXF51_15345	COG5577	PFAM Coat F domain
CXF51_15385	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CXF51_15410	COG1378	Sugar-specific transcriptional regulator TrmB
CXF51_15465	COG5609	conserved protein (DUF2294)
CXF51_15485	COG0626	cystathionine gamma-synthase activity
CXF51_15495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CXF51_15500	COG2226	methyltransferase
CXF51_15520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CXF51_15525	COG0572	uridine kinase
CXF51_15550	COG3906	Belongs to the UPF0473 family
CXF51_15555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CXF51_15560	COG4472	Bacterial protein of unknown function (DUF965)
CXF51_15565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CXF51_15575	COG0628	permease
CXF51_15580	COG1126	abc transporter atp-binding protein
CXF51_15585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXF51_15595	COG0765	amino acid transport
CXF51_15620	COG0457	Tetratricopeptide repeat
CXF51_15635	COG1959	2 iron, 2 sulfur cluster binding
CXF51_15640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CXF51_15645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CXF51_15655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CXF51_15660	COG0124	histidyl-tRNA synthetase
CXF51_15670	COG4991	sh3 domain protein
CXF51_15670	COG3103	Sh3 type 3 domain protein
CXF51_15670	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXF51_15675	COG1490	D-aminoacyl-tRNA deacylase activity
CXF51_15680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CXF51_15685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CXF51_15690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CXF51_15690	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CXF51_15695	COG5416	Lipopolysaccharide assembly protein A domain
CXF51_15700	COG0490	domain, Protein
CXF51_15720	COG2323	membrane
CXF51_15730	COG1862	Preprotein translocase
CXF51_15735	COG0343	queuine tRNA-ribosyltransferase activity
CXF51_15740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CXF51_15750	COG2255	four-way junction helicase activity
CXF51_15755	COG0632	four-way junction helicase activity
CXF51_15770	COG0673	inositol 2-dehydrogenase activity
CXF51_15775	COG2112	serine threonine protein kinase
CXF51_15800	COG0217	transcriptional regulatory protein
CXF51_15815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CXF51_15825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CXF51_15835	COG1827	regulation of RNA biosynthetic process
CXF51_15840	COG0077	Prephenate dehydratase
CXF51_15855	COG3290	protein histidine kinase activity
CXF51_15865	COG2868	ribosomal protein
CXF51_15870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CXF51_15880	COG0739	heme binding
CXF51_15885	COG2894	cell division
CXF51_15895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CXF51_15900	COG1792	Involved in formation and maintenance of cell shape
CXF51_15910	COG2003	Belongs to the UPF0758 family
CXF51_15960	COG0113	porphobilinogen synthase activity
CXF51_15970	COG0181	hydroxymethylbilane synthase activity
CXF51_15975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CXF51_15990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CXF51_16000	COG1067	ATP-dependent peptidase activity
CXF51_16000	COG0470	DNA polymerase III
CXF51_16005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CXF51_16010	COG0544	peptidyl-prolyl cis-trans isomerase activity
CXF51_16015	COG1477	protein flavinylation
CXF51_16015	COG0457	Tetratricopeptide repeat
CXF51_16020	COG0066	3-isopropylmalate dehydratase activity
CXF51_16030	COG0473	3-isopropylmalate dehydrogenase activity
CXF51_16045	COG0440	acetolactate synthase activity
CXF51_16060	COG0454	-acetyltransferase
CXF51_16075	COG0622	Phosphoesterase
CXF51_16080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CXF51_16085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CXF51_16090	COG5401	PFAM Sporulation and spore germination
CXF51_16095	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CXF51_16100	COG1846	Transcriptional regulator
CXF51_16105	COG2197	response regulator
CXF51_16115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CXF51_16120	COG1053	succinate dehydrogenase
CXF51_16125	COG2009	succinate dehydrogenase
CXF51_16130	COG1719	4-vinyl reductase, 4VR
CXF51_16135	COG0527	aspartate kinase activity
CXF51_16150	COG3118	belongs to the thioredoxin family
CXF51_16165	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CXF51_16170	COG2086	electron transfer activity
CXF51_16180	COG1309	transcriptional regulator
CXF51_16190	COG3766	membrane
CXF51_16210	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CXF51_16215	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CXF51_16235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CXF51_16260	COG0346	lactoylglutathione lyase activity
CXF51_16295	COG0371	Dehydrogenase
CXF51_16300	COG0647	UMP catabolic process
CXF51_16310	COG1069	ribulokinase activity
CXF51_16315	COG2160	L-arabinose isomerase activity
CXF51_16320	COG3507	Belongs to the glycosyl hydrolase 43 family
CXF51_16335	COG3326	Membrane
CXF51_16340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CXF51_16345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CXF51_16350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CXF51_16385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CXF51_16395	COG0398	Pfam SNARE associated Golgi protein
CXF51_16400	COG1484	DNA-dependent DNA replication
CXF51_16415	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CXF51_16430	COG2814	Major facilitator Superfamily
CXF51_16435	COG0656	L-ascorbic acid biosynthetic process
CXF51_16440	COG0237	dephospho-CoA kinase activity
CXF51_16455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXF51_16455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CXF51_16460	COG5002	protein histidine kinase activity
CXF51_16465	COG0745	RESPONSE REGULATOR receiver
CXF51_16475	COG0039	L-malate dehydrogenase activity
CXF51_16480	COG0538	isocitrate dehydrogenase activity
CXF51_16490	COG2707	UPF0756 membrane protein
CXF51_16500	COG3030	protein affecting phage T7 exclusion by the F plasmid
CXF51_16505	COG0469	pyruvate kinase activity
CXF51_16510	COG0205	6-phosphofructokinase activity
CXF51_16525	COG0281	malic enzyme
CXF51_16550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CXF51_16565	COG0730	response to heat
CXF51_16580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXF51_16610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CXF51_16625	COG0583	DNA-binding transcription factor activity
CXF51_16630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CXF51_16635	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_16645	COG0165	Argininosuccinate lyase
CXF51_16655	COG0521	Mo-molybdopterin cofactor biosynthetic process
CXF51_16675	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CXF51_16690	COG1714	RDD family
CXF51_16700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CXF51_16705	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CXF51_16710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CXF51_16720	COG0301	tRNA thio-modification
CXF51_16745	COG1309	transcriptional regulator
CXF51_16750	COG1956	GAF domain-containing protein
CXF51_16770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CXF51_16785	COG0454	-acetyltransferase
CXF51_16815	COG1605	Chorismate mutase
CXF51_16815	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CXF51_16820	COG3118	belongs to the thioredoxin family
CXF51_16825	COG4980	gas vesicle protein
CXF51_16835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CXF51_16845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CXF51_16850	COG4848	Belongs to the UPF0354 family
CXF51_16855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CXF51_16865	COG1363	Peptidase, m42
CXF51_16870	COG5584	Small secreted protein
CXF51_16875	COG0281	malic enzyme
CXF51_16895	COG0510	thiamine kinase activity
CXF51_16900	COG1523	belongs to the glycosyl hydrolase 13 family
CXF51_16915	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CXF51_16920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CXF51_16940	COG1131	(ABC) transporter
CXF51_16945	COG1349	DNA-binding transcription factor activity
CXF51_16975	COG5578	integral membrane protein
CXF51_16985	COG1653	transport
CXF51_16990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CXF51_17005	COG1653	transport
CXF51_17015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CXF51_17025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CXF51_17035	COG0156	8-amino-7-oxononanoate synthase activity
CXF51_17050	COG1073	alpha beta
CXF51_17075	COG1486	melibiose metabolic process
CXF51_17085	COG0495	leucyl-tRNA aminoacylation
CXF51_17095	COG1366	Belongs to the anti-sigma-factor antagonist family
CXF51_17095	COG2202	Pas domain
CXF51_17100	COG2814	Major facilitator Superfamily
CXF51_17105	COG2433	Pfam Transposase IS66
CXF51_17115	COG1136	(ABC) transporter
CXF51_17120	COG2205	protein histidine kinase activity
CXF51_17135	COG1136	(ABC) transporter
CXF51_17150	COG1131	(ABC) transporter
CXF51_17160	COG1242	4 iron, 4 sulfur cluster binding
CXF51_17165	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CXF51_17180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CXF51_17195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CXF51_17230	COG0494	nUDIX hydrolase
CXF51_17255	COG1854	S-ribosylhomocysteine lyase activity
CXF51_17260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CXF51_17265	COG0288	reversible hydration of carbon dioxide
CXF51_17270	COG0254	rRNA binding
CXF51_17295	COG1321	iron dependent repressor
CXF51_17295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CXF51_17300	COG1121	(ABC) transporter
CXF51_17315	COG0318	PFAM AMP-dependent synthetase and ligase
CXF51_17325	COG0596	Alpha beta hydrolase
CXF51_17340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CXF51_17375	COG0438	transferase activity, transferring glycosyl groups
CXF51_17380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CXF51_17385	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CXF51_17395	COG0297	glycogen (starch) synthase activity
CXF51_17405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CXF51_17410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CXF51_17535	COG3859	Proton-coupled thiamine transporter YuaJ
CXF51_17540	COG1247	-acetyltransferase
CXF51_17545	COG2268	Band 7 protein
CXF51_17550	COG1585	Membrane protein implicated in regulation of membrane protease activity
CXF51_17555	COG2318	DinB family
CXF51_17565	COG1454	alcohol dehydrogenase
CXF51_17585	COG0569	domain protein
CXF51_17590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CXF51_17610	COG5553	Cysteine dioxygenase type I
CXF51_17625	COG0628	permease
CXF51_17630	COG0673	inositol 2-dehydrogenase activity
CXF51_17640	COG3254	rhamnose metabolic process
CXF51_17645	COG1070	Carbohydrate kinase
CXF51_17650	COG1349	DNA-binding transcription factor activity
CXF51_17675	COG0840	transmembrane signaling receptor activity
CXF51_17695	COG0432	Pfam Uncharacterised protein family UPF0047
CXF51_17710	COG2738	Putative neutral zinc metallopeptidase
CXF51_17750	COG1979	alcohol dehydrogenase
CXF51_17755	COG2155	Conserved Protein
CXF51_17770	COG1522	sequence-specific DNA binding
CXF51_17775	COG2267	carboxylic ester hydrolase activity
CXF51_17785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CXF51_17800	COG5018	Exonuclease
CXF51_17810	COG2814	Major facilitator Superfamily
CXF51_17875	COG2111	Na H antiporter
CXF51_17895	COG2212	antiporter activity
CXF51_17900	COG1320	monovalent cation:proton antiporter activity
CXF51_17905	COG2050	protein possibly involved in aromatic compounds catabolism
CXF51_17925	COG0142	geranyltranstransferase activity
CXF51_17940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CXF51_17950	COG1335	isochorismatase
CXF51_17955	COG5506	Protein of unknown function (DUF1694)
CXF51_17990	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_18020	COG4842	Belongs to the WXG100 family
CXF51_18040	COG0686	Belongs to the AlaDH PNT family
CXF51_18050	COG3251	PFAM MbtH domain protein
CXF51_18060	COG1535	isochorismatase
CXF51_18060	COG3433	isochorismatase activity
CXF51_18065	COG1021	2,3-dihydroxybenzoate-AMP ligase
CXF51_18070	COG1169	isochorismate synthase
CXF51_18075	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_18080	COG2819	hydrolase of the alpha beta superfamily
CXF51_18085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CXF51_18090	COG1268	BioY protein
CXF51_18100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CXF51_18110	COG3584	3D domain protein
CXF51_18125	COG1252	NADH dehydrogenase
CXF51_18140	COG0516	GMP reductase activity
CXF51_18145	COG2808	Putative FMN-binding domain
CXF51_18155	COG0316	Belongs to the HesB IscA family
CXF51_18160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CXF51_18165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXF51_18170	COG4844	belongs to the
CXF51_18175	COG1252	NADH dehydrogenase
CXF51_18180	COG4837	Protein of unknown function (DUF1462)
CXF51_18185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CXF51_18190	COG0823	Involved in the tonB-independent uptake of proteins
CXF51_18190	COG1506	peptidase
CXF51_18190	COG4946	Tricorn protease homolog
CXF51_18195	COG0083	homoserine kinase activity
CXF51_18205	COG0460	homoserine dehydrogenase
CXF51_18215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CXF51_18220	COG0647	UMP catabolic process
CXF51_18225	COG2445	Protein of unknown function DUF86
CXF51_18230	COG4470	Protein conserved in bacteria
CXF51_18240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CXF51_18245	COG0739	heme binding
CXF51_18255	COG3377	Domain of unknown function (DUF1805)
CXF51_18260	COG0737	Belongs to the 5'-nucleotidase family
CXF51_18265	COG0730	response to heat
CXF51_18270	COG1801	Protein of unknown function DUF72
CXF51_18280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CXF51_18285	COG2508	Transcriptional regulator
CXF51_18295	COG2233	PERMEase
CXF51_18300	COG3648	Uricase
CXF51_18300	COG3195	allantoin biosynthetic process
CXF51_18305	COG2351	hydroxyisourate hydrolase activity
CXF51_18315	COG2080	2 iron, 2 sulfur cluster binding
CXF51_18320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CXF51_18340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CXF51_18345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CXF51_18390	COG0322	excinuclease ABC activity
CXF51_18410	COG0346	lactoylglutathione lyase activity
CXF51_18415	COG0640	Transcriptional regulator
CXF51_18420	COG0719	Fe-S assembly protein
CXF51_18425	COG0822	iron-sulfur transferase activity
CXF51_18430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CXF51_18435	COG0719	Fe-S assembly protein
CXF51_18440	COG0396	ATPase activity
CXF51_18455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CXF51_18465	COG2011	ABC-type metal ion transport system permease component
CXF51_18480	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CXF51_18490	COG0509	glycine decarboxylation via glycine cleavage system
CXF51_18495	COG1393	Belongs to the ArsC family
CXF51_18510	COG1250	3-hydroxyacyl-CoA dehydrogenase
CXF51_18510	COG1024	Enoyl-CoA hydratase
CXF51_18520	COG0506	proline dehydrogenase activity
CXF51_18530	COG5577	PFAM Coat F domain
CXF51_18535	COG1846	Transcriptional regulator
CXF51_18550	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_18555	COG0583	DNA-binding transcription factor activity
CXF51_18565	COG1120	ATPase activity
CXF51_18580	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_18585	COG0783	Belongs to the Dps family
CXF51_18590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXF51_18595	COG0745	RESPONSE REGULATOR receiver
CXF51_18600	COG2770	Histidine kinase
CXF51_18600	COG2205	protein histidine kinase activity
CXF51_18610	COG1309	transcriptional regulator
CXF51_18615	COG0114	fumarate hydratase activity
CXF51_18645	COG4585	Histidine kinase
CXF51_18655	COG3595	metallopeptidase activity
CXF51_18670	COG2814	Major facilitator Superfamily
CXF51_18675	COG2096	Adenosyltransferase
CXF51_18695	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_18740	COG0577	efflux transmembrane transporter activity
CXF51_18745	COG1136	(ABC) transporter
CXF51_18750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CXF51_18755	COG1120	ATPase activity
CXF51_18780	COG0531	amino acid
CXF51_18795	COG1988	membrane-bound metal-dependent
CXF51_18800	COG1368	sulfuric ester hydrolase activity
CXF51_18805	COG1910	domain protein
CXF51_18815	COG4149	molybdate abc transporter
CXF51_18830	COG0025	NhaP-type Na H and K H
CXF51_18855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CXF51_18860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CXF51_18875	COG2608	mercury ion transmembrane transporter activity
CXF51_18880	COG1937	Protein conserved in bacteria
CXF51_18885	COG0673	inositol 2-dehydrogenase activity
CXF51_18905	COG2076	Multidrug Resistance protein
CXF51_18910	COG1309	transcriptional regulator
CXF51_18915	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_18925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CXF51_18940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CXF51_18950	COG1476	TRANSCRIPTIONal
CXF51_18955	COG1396	sequence-specific DNA binding
CXF51_18965	COG1733	regulation of RNA biosynthetic process
CXF51_18980	COG1732	Glycine betaine
CXF51_18985	COG1174	glycine betaine transport
CXF51_19005	COG1732	Glycine betaine
CXF51_19010	COG1174	glycine betaine transport
CXF51_19015	COG1125	glycine betaine transport
CXF51_19015	COG0517	IMP dehydrogenase activity
CXF51_19020	COG1510	regulation of RNA biosynthetic process
CXF51_19025	COG2095	MarC family integral membrane protein
CXF51_19035	COG3064	Membrane
CXF51_19040	COG4640	response to antibiotic
CXF51_19045	COG0456	acetyltransferase
CXF51_19050	COG0148	phosphopyruvate hydratase activity
CXF51_19055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CXF51_19060	COG0149	triose-phosphate isomerase activity
CXF51_19065	COG0126	phosphoglycerate kinase activity
CXF51_19070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CXF51_19080	COG2814	Major facilitator Superfamily
CXF51_19090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXF51_19100	COG0583	DNA-binding transcription factor activity
CXF51_19105	COG0697	spore germination
CXF51_19110	COG0697	spore germination
CXF51_19115	COG0697	spore germination
CXF51_19135	COG1139	Iron-sulfur cluster binding protein
CXF51_19140	COG0247	lactate metabolic process
CXF51_19145	COG2197	response regulator
CXF51_19155	COG0842	Transport permease protein
CXF51_19160	COG1131	(ABC) transporter
CXF51_19165	COG0596	Alpha beta hydrolase
CXF51_19170	COG2208	phosphoserine phosphatase activity
CXF51_19185	COG3833	ABC-type maltose transport systems, permease component
CXF51_19205	COG2186	Transcriptional regulator
CXF51_19225	COG5039	Polysaccharide pyruvyl transferase
CXF51_19250	COG1216	Glycosyl transferase, family 2
CXF51_19260	COG1216	Glycosyl transferase, family 2
CXF51_19270	COG0438	transferase activity, transferring glycosyl groups
CXF51_19275	COG1215	transferase activity, transferring glycosyl groups
CXF51_19280	COG0438	transferase activity, transferring glycosyl groups
CXF51_19285	COG1086	Polysaccharide biosynthesis protein
CXF51_19295	COG3944	biosynthesis protein
CXF51_19315	COG3479	Phenolic acid decarboxylase
CXF51_19325	COG1794	racemase activity, acting on amino acids and derivatives
CXF51_19345	COG0531	amino acid
CXF51_19350	COG1309	transcriptional regulator
CXF51_19360	COG2076	Multidrug Resistance protein
CXF51_19375	COG3621	Patatin-like phospholipase
CXF51_19385	COG0740	serine-type endopeptidase activity
CXF51_19395	COG0366	Alpha amylase catalytic
CXF51_19400	COG1554	hydrolase, family 65, central catalytic
CXF51_19405	COG5521	maltodextrose utilization protein MalA
CXF51_19415	COG1175	transmembrane transport
CXF51_19420	COG2182	Extracellular solute-binding protein
CXF51_19435	COG1611	Belongs to the LOG family
CXF51_19440	COG1694	Mazg nucleotide pyrophosphohydrolase
CXF51_19445	COG0659	secondary active sulfate transmembrane transporter activity
CXF51_19450	COG0288	reversible hydration of carbon dioxide
CXF51_19460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CXF51_19465	COG0577	efflux transmembrane transporter activity
CXF51_19470	COG1136	(ABC) transporter
CXF51_19495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CXF51_19510	COG1660	Displays ATPase and GTPase activities
CXF51_19515	COG1051	belongs to the nudix hydrolase family
CXF51_19520	COG0492	ferredoxin-NADP+ reductase activity
CXF51_19560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CXF51_19560	COG0140	phosphoribosyl-ATP diphosphatase activity
CXF51_19565	COG0107	imidazoleglycerol-phosphate synthase activity
CXF51_19575	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CXF51_19580	COG0131	Imidazoleglycerol-phosphate dehydratase
CXF51_19590	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CXF51_19595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CXF51_19600	COG4990	cell redox homeostasis
CXF51_19610	COG0110	maltose O-acetyltransferase activity
CXF51_19615	COG0546	phosphoglycolate phosphatase activity
CXF51_19635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CXF51_19640	COG0363	glucosamine-6-phosphate deaminase activity
CXF51_19660	COG2124	cytochrome p450
CXF51_19680	COG1950	PFAM Membrane protein of
CXF51_19685	COG1983	PspC domain protein
CXF51_19705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXF51_19715	COG0556	nucleotide-excision repair
CXF51_19720	COG4897	Protein conserved in bacteria
CXF51_19730	COG1309	transcriptional regulator
CXF51_19740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXF51_19755	COG2177	Part of the ABC transporter FtsEX involved in
CXF51_19760	COG2884	Cell division ATP-binding protein ftsE
CXF51_19775	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CXF51_19785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CXF51_19800	COG1516	flagellar protein fliS
CXF51_19810	COG1334	flagellar protein FlaG
CXF51_19815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXF51_19820	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CXF51_19835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CXF51_19860	COG1040	competence protein
CXF51_19890	COG1739	Uncharacterized protein family UPF0029
CXF51_19915	COG1215	transferase activity, transferring glycosyl groups
CXF51_19925	COG3307	-O-antigen
CXF51_19935	COG0438	transferase activity, transferring glycosyl groups
CXF51_19935	COG0297	glycogen (starch) synthase activity
CXF51_19940	COG2244	polysaccharide biosynthetic process
CXF51_19950	COG0860	N-Acetylmuramoyl-L-alanine amidase
CXF51_19950	COG2247	cell wall binding repeat
CXF51_19955	COG2385	sporulation resulting in formation of a cellular spore
CXF51_19955	COG2247	cell wall binding repeat
CXF51_19965	COG1316	TRANSCRIPTIONal
CXF51_19975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXF51_20010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CXF51_20020	COG1682	transport, permease protein
CXF51_20030	COG0438	transferase activity, transferring glycosyl groups
CXF51_20035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CXF51_20040	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CXF51_20055	COG4193	domain, Protein
CXF51_20065	COG0697	spore germination
CXF51_20080	COG2814	Major facilitator Superfamily
CXF51_20095	COG0791	NLP P60 protein
CXF51_20125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXF51_20130	COG1869	D-ribose catabolic process
CXF51_20140	COG1172	Belongs to the binding-protein-dependent transport system permease family
CXF51_20150	COG3103	Sh3 type 3 domain protein
CXF51_20160	COG2249	NAD(P)H dehydrogenase (quinone) activity
CXF51_20165	COG3527	Alpha-acetolactate decarboxylase
CXF51_20175	COG0583	DNA-binding transcription factor activity
CXF51_20205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CXF51_20215	COG0405	Gamma-glutamyltransferase
CXF51_20220	COG1522	sequence-specific DNA binding
CXF51_20225	COG2059	Chromate
CXF51_20230	COG2059	Chromate
CXF51_20240	COG0655	NAD(P)H dehydrogenase (quinone) activity
CXF51_20245	COG0583	DNA-binding transcription factor activity
CXF51_20315	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CXF51_20330	COG3944	biosynthesis protein
CXF51_20360	COG0629	single-stranded DNA binding
CXF51_20375	COG3764	Sortase (surface protein transpeptidase)
CXF51_20385	COG1970	mechanosensitive ion channel activity
CXF51_20390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CXF51_20395	COG0457	Tetratricopeptide repeat
CXF51_20405	COG4786	Flagellar basal body rod
CXF51_20410	COG1077	Cell shape determining protein MreB Mrl
CXF51_20415	COG1609	Transcriptional regulator
CXF51_20425	COG1846	Transcriptional regulator
CXF51_20430	COG2814	Major facilitator Superfamily
CXF51_20445	COG0477	Major facilitator Superfamily
CXF51_20485	COG1247	-acetyltransferase
CXF51_20500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXF51_20505	COG0789	Transcriptional regulator
CXF51_20515	COG2910	NAD(P)H-binding
CXF51_20520	COG1959	2 iron, 2 sulfur cluster binding
CXF51_20530	COG0832	Belongs to the urease beta subunit family
CXF51_20535	COG0831	urea catabolic process
CXF51_20550	COG3237	CsbD-like
CXF51_20555	COG1994	Peptidase M50
CXF51_20560	COG0457	Tetratricopeptide repeat
CXF51_20575	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CXF51_20585	COG2304	oxidoreductase activity
CXF51_20590	COG2304	oxidoreductase activity
CXF51_20595	COG2385	sporulation resulting in formation of a cellular spore
CXF51_20600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CXF51_20620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CXF51_20625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CXF51_20630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CXF51_20635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CXF51_20640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CXF51_20645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CXF51_20650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CXF51_20655	COG0356	it plays a direct role in the translocation of protons across the membrane
CXF51_20665	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CXF51_20670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CXF51_20675	COG4475	Protein of unknown function (DUF436)
CXF51_20680	COG0698	ribose 5-phosphate isomerase
CXF51_20685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CXF51_20690	COG1971	Probably functions as a manganese efflux pump
CXF51_20720	COG2890	protein-(glutamine-N5) methyltransferase activity
CXF51_20725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CXF51_20730	COG0346	lactoylglutathione lyase activity
CXF51_20735	COG0789	Transcriptional regulator
CXF51_20750	COG1435	thymidine kinase activity
CXF51_20755	COG0254	rRNA binding
CXF51_20775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CXF51_20780	COG0191	fructose-bisphosphate aldolase activity
CXF51_20785	COG2204	response regulator
CXF51_20790	COG4821	SIS domain
CXF51_20805	COG1960	acyl-CoA dehydrogenase activity
CXF51_20810	COG0247	lactate metabolic process
CXF51_20810	COG2181	nitrate reductase activity
CXF51_20815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXF51_20820	COG4294	response to UV
CXF51_20840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CXF51_20845	COG2181	nitrate reductase activity
CXF51_20850	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CXF51_20855	COG1140	nitrate reductase beta subunit
CXF51_20860	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CXF51_20865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CXF51_20890	COG4506	Protein conserved in bacteria
CXF51_20905	COG0535	radical SAM domain protein
CXF51_20915	COG1131	(ABC) transporter
CXF51_20920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CXF51_20930	COG0612	Peptidase, M16
CXF51_20940	COG3391	amine dehydrogenase activity
CXF51_20945	COG3391	amine dehydrogenase activity
CXF51_20995	COG0010	Belongs to the arginase family
CXF51_21000	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CXF51_21015	COG1994	Peptidase M50
CXF51_21020	COG1942	4-Oxalocrotonate Tautomerase
CXF51_21025	COG1846	Transcriptional regulator
CXF51_21030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CXF51_21040	COG1959	2 iron, 2 sulfur cluster binding
CXF51_21045	COG3465	dGTPase activity
CXF51_21050	COG1078	dGTPase activity
CXF51_21070	COG0095	Lipoate-protein ligase
CXF51_21075	COG0583	DNA-binding transcription factor activity
CXF51_21080	COG0280	phosphate acetyltransferase
CXF51_21090	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_21115	COG1917	Cupin 2, conserved barrel domain protein
CXF51_21125	COG2814	Major facilitator Superfamily
CXF51_21135	COG4187	Peptidase family M20/M25/M40
CXF51_21140	COG1012	belongs to the aldehyde dehydrogenase family
CXF51_21155	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CXF51_21170	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CXF51_21175	COG3980	spore coat polysaccharide biosynthesis protein
CXF51_21180	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CXF51_21240	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CXF51_21245	COG1216	Glycosyl transferase, family 2
CXF51_21260	COG1695	Transcriptional regulator
CXF51_21265	COG0351	phosphomethylpyrimidine kinase
CXF51_21285	COG2116	formate transmembrane transporter activity
CXF51_21305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CXF51_21310	COG0778	Nitroreductase
CXF51_21325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CXF51_21330	COG1845	cytochrome c oxidase, subunit III
CXF51_21335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CXF51_21350	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CXF51_21375	COG3162	membrane
CXF51_21380	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CXF51_21385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CXF51_21395	COG2822	iron ion transport
CXF51_21400	COG0672	)-iron permease
CXF51_21405	COG0352	thiamine-phosphate diphosphorylase activity
CXF51_21410	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CXF51_21415	COG0583	DNA-binding transcription factor activity
CXF51_21425	COG1346	cytolysis
CXF51_21430	COG2814	Major facilitator Superfamily
CXF51_21435	COG4895	conserved protein (DUF2196)
CXF51_21440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CXF51_21465	COG3711	transcriptional antiterminator
CXF51_21515	COG1575	Belongs to the MenA family. Type 1 subfamily
CXF51_21530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CXF51_21540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CXF51_21560	COG1486	melibiose metabolic process
CXF51_21565	COG1447	Phosphotransferase system cellobiose-specific component IIA
CXF51_21570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CXF51_21590	COG2094	Belongs to the DNA glycosylase MPG family
CXF51_21630	COG1595	DNA-templated transcription, initiation
CXF51_21645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CXF51_21655	COG1294	oxidase, subunit
CXF51_21660	COG1271	oxidase subunit
CXF51_21670	COG0501	Belongs to the peptidase M48B family
CXF51_21680	COG0726	polysaccharide deacetylase
CXF51_21690	COG2508	Transcriptional regulator
CXF51_21695	COG1012	belongs to the aldehyde dehydrogenase family
CXF51_21710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CXF51_21725	COG2197	response regulator
CXF51_21730	COG2195	Cleaves the N-terminal amino acid of tripeptides
CXF51_21740	COG4894	glucomannan catabolic process
CXF51_21755	COG1028	Short-chain dehydrogenase reductase Sdr
CXF51_21765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CXF51_21775	COG0500	methyltransferase
CXF51_21780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXF51_21795	COG0693	protein deglycase activity
CXF51_21795	COG0753	catalase activity
CXF51_21800	COG2851	Citrate transporter
CXF51_21810	COG3711	transcriptional antiterminator
CXF51_21820	COG2270	Major facilitator Superfamily
CXF51_21825	COG0513	Belongs to the DEAD box helicase family
CXF51_21830	COG3401	FG-GAP repeat protein
CXF51_21830	COG2755	lipolytic protein G-D-S-L family
CXF51_21905	COG0789	Transcriptional regulator
CXF51_21960	COG3507	Belongs to the glycosyl hydrolase 43 family
CXF51_21975	COG2986	histidine ammonia-lyase
CXF51_21985	COG1228	amidohydrolase
CXF51_22000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CXF51_22005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CXF51_22015	COG2390	Transcriptional regulator
CXF51_22025	COG3192	ethanolamine utilization protein
CXF51_22030	COG2079	MmgE PrpD family protein
CXF51_22040	COG1126	abc transporter atp-binding protein
CXF51_22070	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CXF51_22075	COG0561	phosphatase activity
CXF51_22105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CXF51_22110	COG5294	Protein conserved in bacteria
CXF51_22120	COG1136	(ABC) transporter
CXF51_22125	COG2205	protein histidine kinase activity
CXF51_22130	COG0745	RESPONSE REGULATOR receiver
CXF51_22135	COG0191	fructose-bisphosphate aldolase activity
CXF51_22140	COG1082	Xylose isomerase domain protein TIM barrel
CXF51_22145	COG1082	Xylose isomerase domain protein TIM barrel
CXF51_22150	COG0673	inositol 2-dehydrogenase activity
CXF51_22160	COG1082	Xylose isomerase domain protein TIM barrel
CXF51_22170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CXF51_22175	COG3718	enzyme involved in inositol metabolism
CXF51_22180	COG1012	belongs to the aldehyde dehydrogenase family
CXF51_22185	COG1349	DNA-binding transcription factor activity
CXF51_22205	COG2814	Major facilitator Superfamily
CXF51_22210	COG0326	Molecular chaperone. Has ATPase activity
CXF51_22235	COG0456	acetyltransferase
CXF51_22265	COG2814	Major facilitator Superfamily
CXF51_22270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CXF51_22280	COG1714	RDD family
CXF51_22285	COG2311	Membrane
CXF51_22295	COG1309	transcriptional regulator
CXF51_22305	COG1846	Transcriptional regulator
CXF51_22315	COG1346	cytolysis
CXF51_22330	COG1802	Transcriptional regulator
CXF51_22345	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CXF51_22350	COG0450	alkyl hydroperoxide reductase
CXF51_22355	COG3634	alkyl hydroperoxide reductase activity
CXF51_22360	COG2723	6-phospho-beta-galactosidase activity
CXF51_22410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CXF51_22445	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CXF51_22450	COG0456	acetyltransferase
CXF51_22465	COG0010	Belongs to the arginase family
CXF51_22470	COG0833	amino acid
CXF51_22475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CXF51_22480	COG3829	transcription factor binding
CXF51_22485	COG5002	protein histidine kinase activity
CXF51_22505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CXF51_22510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CXF51_22515	COG4853	Protein conserved in bacteria
CXF51_22525	COG5002	protein histidine kinase activity
CXF51_22530	COG0745	RESPONSE REGULATOR receiver
CXF51_22565	COG0305	Participates in initiation and elongation during chromosome replication
CXF51_22580	COG3093	addiction module antidote protein HigA
CXF51_22585	COG2807	transmembrane transport
CXF51_22605	COG4241	membrane
CXF51_22615	COG5577	PFAM Coat F domain
CXF51_22620	COG1733	regulation of RNA biosynthetic process
CXF51_22625	COG1227	inorganic diphosphatase activity
CXF51_22635	COG2271	Major facilitator Superfamily
CXF51_22655	COG1357	PFAM Pentapeptide repeats (8 copies)
CXF51_22670	COG2153	protein acetylation
CXF51_22685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CXF51_22695	COG2153	protein acetylation
CXF51_22700	COG2364	Membrane
CXF51_22705	COG0456	acetyltransferase
CXF51_22715	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CXF51_22735	COG1331	Highly conserved protein containing a thioredoxin domain
CXF51_22740	COG0789	Transcriptional regulator
CXF51_22740	COG4978	Transcriptional regulator
CXF51_22745	COG1811	Na channel or pump
CXF51_22750	COG1331	Highly conserved protein containing a thioredoxin domain
CXF51_22765	COG0477	Major facilitator Superfamily
CXF51_22765	COG2814	Major facilitator Superfamily
CXF51_22770	COG0110	maltose O-acetyltransferase activity
CXF51_22775	COG0346	lactoylglutathione lyase activity
CXF51_22780	COG1609	Transcriptional regulator
CXF51_22785	COG0708	Exodeoxyribonuclease III
CXF51_22790	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CXF51_22800	COG0360	Binds together with S18 to 16S ribosomal RNA
CXF51_22805	COG0012	GTP binding
CXF51_22810	COG0243	molybdopterin cofactor binding
CXF51_22815	COG4481	Protein conserved in bacteria
CXF51_22820	COG3949	Membrane
CXF51_22835	COG1192	Involved in chromosome partitioning
CXF51_22845	COG1475	DNA binding
CXF51_22850	COG0357	Ribosomal RNA small subunit methyltransferase G
CXF51_22875	COG0594	ribonuclease P activity
CXF51_22880	COG0230	Belongs to the bacterial ribosomal protein bL34 family