locus-tag class description AT706_00080 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AT706_00085 ENOG410815N Probably functions as a manganese efflux pump (By similarity) AT706_00090 ENOG4107WAU Protein tyrosine phosphatase AT706_00095 ENOG4108YZG isomerase AT706_00100 ENOG4108UIC UPF0340 protein AT706_00105 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) AT706_00110 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) AT706_00120 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) AT706_00145 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) AT706_00150 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) AT706_00155 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) AT706_00160 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) AT706_00170 ENOG4106778 Protein of unknown function (DUF1146) AT706_00180 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) AT706_00185 ENOG4105JFG SpoIID LytB domain protein AT706_00200 ENOG4108TF4 von Willebrand factor, type A AT706_00210 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) AT706_00245 ENOG4108YZ9 Urea amidohydrolase subunit gamma AT706_00250 ENOG4105KI2 Urea amidohydrolase subunit beta AT706_00255 ENOG4105CQM Urea amidohydrolase subunit alpha AT706_00260 ENOG4108Z40 Transcriptional regulator AT706_00265 ENOG4108RYK Nad-dependent epimerase dehydratase AT706_00270 ENOG4106BRK AT706_00275 ENOG4107TXC Transcriptional regulator AT706_00280 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AT706_00290 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) AT706_00300 ENOG4107TCE N-acetyltransferase AT706_00305 ENOG4105FRN stage II sporulation protein AT706_00315 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AT706_00325 ENOG4105BZU Histidine kinase AT706_00330 ENOG4107P26 AT706_00335 ENOG4105D3W isochorismatase AT706_00340 ENOG41080V3 Major Facilitator superfamily AT706_00345 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease AT706_00350 ENOG4108M26 parallel beta-helix repeat protein AT706_00355 ENOG4105CZM Major Facilitator AT706_00360 ENOG4107MII Sugar-specific transcriptional regulator TrmB AT706_00365 ENOG4105MT0 Sporulation transcriptional regulator spoiiid AT706_00370 ENOG4105DFF Rod shape-determining protein mreb AT706_00380 ENOG4105CGA flagellar basal-body rod protein FlgG AT706_00390 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) AT706_00395 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) AT706_00405 ENOG4108VAC response regulator AT706_00430 ENOG4105Z8H single-stranded DNA-binding protein AT706_00435 ENOG4105E98 transcriptional regulator DeoR family AT706_00440 ENOG410667J hydrolase AT706_00445 ENOG4105C0D helicase AT706_00450 ENOG4105KBK Zinc finger, swim domain protein AT706_00460 ENOG4105HTX biosynthesis protein AT706_00465 ENOG4107YJ4 chain length determinant protein AT706_00470 ENOG4108RB3 Capsular polysaccharide biosynthesis protein AT706_00475 ENOG4105C6Y Udp-glucose 6-dehydrogenase AT706_00480 ENOG4108XI2 Domain of unknown function (DUF1963) AT706_00520 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) AT706_00525 ENOG4105FGV Chromate AT706_00530 ENOG4105CAH Chromate AT706_00540 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AT706_00550 ENOG4107XC4 flavin reductase domain protein, FMN-binding AT706_00565 ENOG4106UIA AT706_00580 ENOG4107RSM transcriptional regulator AT706_00590 ENOG4107FQX Alpha-acetolactate decarboxylase AT706_00595 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AT706_00610 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AT706_00615 ENOG4105CNN ABC, transporter AT706_00620 ENOG4105C2J ABC transporter AT706_00625 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) AT706_00630 ENOG4108RVA ribokinase AT706_00635 ENOG4105ETE Transcriptional regulator (LacI family AT706_00640 ENOG4105N98 Capsule biosynthesis protein capB AT706_00650 ENOG4105PNM synthesis protein AT706_00660 ENOG4105K4H Nlp p60 protein AT706_00665 ENOG4105J7I hydrolase AT706_00670 ENOG4108KGH TRANSCRIPTIONal AT706_00675 ENOG4105C54 Major Facilitator superfamily AT706_00680 ENOG4108NHD germination protein AT706_00700 ENOG4105DG6 mannose-6-phosphate isomerase AT706_00750 ENOG41088M2 Glycosyl transferase family 2 AT706_00775 ENOG4105EY8 ABC transporter AT706_00780 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AT706_00800 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AT706_00815 ENOG4105JFG SpoIID LytB domain protein AT706_00820 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AT706_00830 ENOG4105D3Q Sugar transferase AT706_00835 ENOG4105PSV Polysaccharide Biosynthesis Protein AT706_00840 ENOG4107RA4 Glycosyl transferase (Group 1 AT706_00845 ENOG4105C6Y Udp-glucose 6-dehydrogenase AT706_00850 ENOG4105QZI O-Antigen Polymerase AT706_00865 ENOG4107EF8 Glycosyl transferase (Group 1 AT706_00870 ENOG4105ESV Glycosyl transferase, family 4 AT706_00875 ENOG4108KGH TRANSCRIPTIONal AT706_00880 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AT706_00885 ENOG4105BZU Histidine kinase AT706_00890 ENOG4105WH1 Two component transcriptional regulator luxr family AT706_00910 ENOG41081UC Inherit from COG: Competence protein AT706_00915 ENOG4105RU3 AT706_00930 ENOG4105E1Q flagellar hook-associated protein AT706_00935 ENOG4105DTJ flagellar hook-associated protein AT706_00940 ENOG4105MKD AT706_00945 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) AT706_00950 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) AT706_00955 ENOG4105I03 Flagellin AT706_00960 ENOG41083S7 flagellar protein FlaG AT706_00965 ENOG4107RT6 flagellar hook-associated AT706_00970 ENOG4105MQ3 flagellar protein FliS AT706_00985 ENOG4105MS2 ribosomal subunit Interface protein AT706_00995 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) AT706_01010 ENOG4105CAK Cell division ATP-binding protein ftsE AT706_01015 ENOG4105CRP Part of the ABC transporter FtsEX involved in AT706_01020 ENOG4105CN1 protease AT706_01040 ENOG4105MKU Transcriptional regulator AT706_01055 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) AT706_01060 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AT706_01065 ENOG4105I03 Flagellin AT706_01080 ENOG4108PY7 AT706_01085 ENOG41067S9 phage shock protein C, PspC AT706_01090 ENOG41086DT Membrane protein of unknown function AT706_01095 ENOG41088CQ domain protein AT706_01100 ENOG4105FDP GntR family transcriptional regulator AT706_01105 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) AT706_01110 ENOG4105CE4 GlcNAc 6-P deacetylase AT706_01115 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) AT706_01120 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) AT706_01125 ENOG4105HKU nucleoside recognition domain-containing protein AT706_01130 ENOG4107XGZ Hydrolase AT706_01135 ENOG4108S4C acetyltransferase AT706_01140 ENOG4108E16 pectate lyase AT706_01150 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) AT706_01155 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) AT706_01160 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AT706_01165 ENOG4105ECC imidazole-glycerol-phosphate dehydratase AT706_01170 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) AT706_01175 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase AT706_01180 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) AT706_01185 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AT706_01195 ENOG4106FGC AT706_01205 ENOG4105BZ1 (ABC) transporter AT706_01220 ENOG4105C3M thioredoxin reductase AT706_01225 ENOG4108Z4K mutator MutT protein AT706_01230 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) AT706_01235 ENOG4105CHW UPF0052 protein AT706_01240 ENOG4105CIE May be required for sporulation (By similarity) AT706_01245 ENOG4105KRI phosphocarrier protein (HPr AT706_01250 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase AT706_01255 ENOG4107A6P AT706_01265 ENOG4105EWM Histidine kinase AT706_01270 ENOG4105C19 ABC transporter AT706_01280 ENOG4105C5I Dehydrogenase AT706_01285 ENOG4108V2W Carbonate dehydratase AT706_01290 ENOG4105CHH sulfate transporter AT706_01295 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain AT706_01300 ENOG4108URH decarboxylase AT706_01305 ENOG4105FKQ transcriptional regulator AT706_01310 ENOG4108IUK alpha amylase, catalytic AT706_01315 ENOG4107FKK extracellular solute-binding protein family 1 AT706_01320 ENOG4105D56 permease protein AT706_01325 ENOG4105EG2 ABC transporter, permease AT706_01340 ENOG4105CG3 alpha amylase, catalytic region AT706_01345 ENOG4107URF beta-phospho-glucomutase AT706_01350 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) AT706_01410 ENOG4107QTZ amino acid AT706_01415 ENOG4108HKT sucrose-6-phosphate hydrolase AT706_01420 ENOG4105EDQ levansucrase EC 2.4.1.10 AT706_01440 ENOG4105NI3 Protein of unknown function (DUF3237) AT706_01445 ENOG4105PY6 Phenolic acid decarboxylase AT706_01455 ENOG4105EBR Carboxylesterase AT706_01465 ENOG4105HTX biosynthesis protein AT706_01470 ENOG4108QV3 biosynthesis protein AT706_01480 ENOG4108PQP glycosyl transferase group 1 AT706_01485 ENOG4105K64 Glycosyl transferase, family 2 AT706_01490 ENOG4108KMV Glycosyl transferase (Group 1 AT706_01495 ENOG41068W6 Capsular polysaccharide biosynthesis protein AT706_01500 ENOG4107QRS glycosyltransferase group 2 family protein AT706_01510 ENOG4105K64 Glycosyl transferase, family 2 AT706_01520 ENOG4105D3Q Sugar transferase AT706_01525 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family AT706_01530 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AT706_01535 ENOG4108ZPC Polysaccharide pyruvyl transferase AT706_01545 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AT706_01550 ENOG4105DAA L-lactate AT706_01555 ENOG4105JXH GntR family transcriptional regulator AT706_01565 ENOG4107FKK extracellular solute-binding protein family 1 AT706_01575 ENOG4105EG2 ABC transporter, permease AT706_01590 ENOG4108MJI response regulator AT706_01595 ENOG4107R6F Alpha Beta Hydrolase Fold protein AT706_01600 ENOG4108M15 ABC transporter AT706_01605 ENOG4105KCT ABC transporter AT706_01610 ENOG4105BZU Histidine kinase AT706_01620 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AT706_01625 ENOG4107QR9 Iron-sulfur cluster binding protein AT706_01630 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) AT706_01635 ENOG4105VRS hydrolase family 18 AT706_01645 ENOG4107RT3 EamA-like transporter family AT706_01650 ENOG4105GZI Transcriptional regulator AT706_01655 ENOG4105DEN Luciferase family AT706_01660 ENOG4105CMD Transcriptional regulator, GntR family AT706_01675 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AT706_01685 ENOG4105BZA Phosphoglycerate kinase AT706_01690 ENOG4105CP7 Triose-phosphate isomerase AT706_01695 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) AT706_01700 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) AT706_01705 ENOG4105IIU Aminopeptidase AT706_01710 ENOG4107QQG Dehydrogenase AT706_01715 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AT706_01720 ENOG4108IAJ Nad-dependent epimerase dehydratase AT706_01740 ENOG4105FJR Lmbe family AT706_01755 ENOG4108W0I acetyltransferase AT706_01760 ENOG4105T65 Membrane-associated protein AT706_01770 ENOG4108QCI YvbH-like oligomerisation region AT706_01775 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein AT706_01780 ENOG4107HG4 Transcriptional regulator AT706_01785 ENOG4108IJ8 ABC transporter AT706_01790 ENOG4105E90 ABC transporter AT706_01795 ENOG4108HQR Glycine betaine AT706_01800 ENOG4105R40 Glycine betaine carnitine choline AT706_01805 ENOG4107HG4 Transcriptional regulator AT706_01810 ENOG4108IJ8 ABC transporter AT706_01815 ENOG4105E90 ABC transporter AT706_01820 ENOG4108HQR Glycine betaine AT706_01825 ENOG4105R40 Glycine betaine carnitine choline AT706_01830 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin AT706_01850 ENOG4105KVH Transcriptional regulator AT706_01875 ENOG4105XZU Preprotein translocase, subunit SecG AT706_01885 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AT706_01890 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) AT706_01895 ENOG4105EWI Short-chain dehydrogenase reductase Sdr AT706_01900 ENOG4105KBX Transcriptional regulator, TetR family AT706_01905 ENOG4105KPY Small multidrug resistance protein AT706_01910 ENOG4105RXJ AT706_01915 ENOG4105ME7 Membrane AT706_01920 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AT706_01925 ENOG4105D9R oxidoreductase AT706_01930 ENOG4105VPX protein, conserved in bacteria AT706_01935 ENOG410681U heavy metal transport detoxification protein AT706_01940 ENOG4105C59 p-type ATPase AT706_01945 ENOG4105C59 p-type ATPase AT706_01950 ENOG4107ZQN disulfide bond AT706_01960 ENOG4105EN6 Membrane AT706_01970 ENOG4105EEM helicase AT706_01975 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AT706_01980 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) AT706_01985 ENOG4105EEQ Na H antiporter AT706_02000 ENOG4105E0C molybdate abc transporter AT706_02005 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AT706_02010 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family AT706_02015 ENOG4107QZ2 Sulfatase AT706_02020 ENOG4107K5X Membrane-bound metal-dependent hydrolase AT706_02030 ENOG4105D5Q Arginine ornithine antiporter AT706_02040 ENOG4105DQ5 transport system permease protein AT706_02045 ENOG4105EHG Permease protein AT706_02050 ENOG4105E0A ABC, transporter AT706_02055 ENOG4108WMK Efflux transporter RND family MFP subunit AT706_02060 ENOG4105C19 ABC transporter AT706_02065 ENOG4107RBB ABC transporter, permease AT706_02075 ENOG4105F0F Oxalate decarboxylase AT706_02085 ENOG4106DF4 Sigma-70, region 4 AT706_02095 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AT706_02105 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein AT706_02110 ENOG4105EWI Short-chain dehydrogenase reductase Sdr AT706_02120 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) AT706_02125 ENOG4105EHG Permease protein AT706_02130 ENOG4105E0A ABC, transporter AT706_02135 ENOG4108WBT adenosyltransferase AT706_02150 ENOG41087YS Phage shock protein A AT706_02165 ENOG4105ENE Histidine kinase AT706_02170 ENOG4105WH1 Two component transcriptional regulator luxr family AT706_02195 ENOG4105C9Q fumarate hydratase class II AT706_02200 ENOG41067SE Tetr family transcriptional regulator AT706_02210 ENOG4105F3H Histidine kinase AT706_02220 ENOG4105C0H protease AT706_02225 ENOG4105HUF DNA protection during starvation protein AT706_02230 ENOG4105E1F short-chain dehydrogenase reductase AT706_02245 ENOG4105E0A ABC, transporter AT706_02255 ENOG4105EGI Transcriptional regulator AT706_02265 ENOG4105MDS 4-oxalocrotonate tautomerase AT706_02270 ENOG4105C0R drug resistance transporter emrb qaca subfamily AT706_02275 ENOG41067TZ transcriptional regulator, MarR family AT706_02305 ENOG4105CHU acetyl-coa acetyltransferase AT706_02310 ENOG4105C1G acyl-Coa dehydrogenase AT706_02315 ENOG41080E8 Transcriptional regulator, Spx MgsR family AT706_02320 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) AT706_02345 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) AT706_02350 ENOG4108UMI ABC transporter, permease AT706_02355 ENOG4105D01 (LipO)protein AT706_02370 ENOG4105C3K feS assembly ATPase SufC AT706_02375 ENOG4105JRK feS assembly protein SufD AT706_02380 ENOG4105C9B Cysteine desulfurase AT706_02385 ENOG4108UNV SUF system FeS assembly protein, NifU family AT706_02390 ENOG4105DIW FeS assembly protein SUFB AT706_02395 ENOG4105NPE arsR family transcriptional regulator AT706_02400 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase AT706_02415 ENOG4107VFR oxidoreductase AT706_02420 ENOG4105PKS Excinuclease abc c subunit domain protein AT706_02425 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine AT706_02430 ENOG4105XN3 extracellular solute-binding protein family 1 AT706_02435 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component AT706_02440 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component AT706_02445 ENOG4108KPW sugar kinase AT706_02450 ENOG4105FDP GntR family transcriptional regulator AT706_02455 ENOG4108IJ9 (ABC) transporter AT706_02460 ENOG4108K8S endonuclease I AT706_02475 ENOG4105C5R Aminotransferase AT706_02480 ENOG4105XRQ Xanthine dehydrogenase accessory factor AT706_02495 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding AT706_02500 ENOG4107YV9 domain protein AT706_02510 ENOG4105VT2 5-hydroxyisourate hydrolase AT706_02515 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) AT706_02530 ENOG4105G9B Transcriptional regulator AT706_02535 ENOG4105CD3 dihydroorotase AT706_02545 ENOG4105I3N Conserved Protein AT706_02555 ENOG4107R8B 5'-nucleotidase AT706_02560 ENOG4105KZD Domain of unknown function (DUF1805) AT706_02565 ENOG4108YTE sporulation protein YunB AT706_02570 ENOG4105FAA peptidase M23 AT706_02575 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) AT706_02580 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) AT706_02585 ENOG4105MMD transcriptional regulator AT706_02595 ENOG4105D4U had-superfamily hydrolase, subfamily iia AT706_02600 ENOG4108W5N phosphatidylglycerophosphatase a AT706_02610 ENOG4105D6E homoserine dehydrogenase AT706_02615 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) AT706_02620 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) AT706_02625 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein AT706_02630 ENOG41083MR nifu domain-containing protein AT706_02645 ENOG4105ZKE UPF0349 protein AT706_02660 ENOG4108YX9 iron--sulfur cluster insertion protein erpA AT706_02665 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 AT706_02685 ENOG4105CAY ferredoxin--nadp reductase AT706_02690 ENOG4105CEP NADH dehydrogenase AT706_02705 ENOG41069ER domain protein AT706_02715 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) AT706_02735 ENOG4105NIV Esterase AT706_02740 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase AT706_02745 ENOG4105E4F Isochorismate synthase AT706_02750 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase AT706_02755 ENOG4105WQI isochorismatase AT706_02760 ENOG4105CEY Amp-dependent synthetase and ligase AT706_02765 ENOG4105WQT MbtH domain protein AT706_02775 ENOG4105DCF alanine dehydrogenase AT706_02780 ENOG4108K8K Transcriptional regulator AT706_02815 ENOG410904N short-chain dehydrogenase reductase AT706_02835 ENOG4105C02 permease AT706_02860 ENOG4105DAP Nicotinate phosphoribosyltransferase AT706_02865 ENOG4105D58 Diguanylate phosphodiesterase AT706_02890 ENOG4105BZU Histidine kinase AT706_02900 ENOG4105KA0 thioesterase Superfamily protein AT706_02905 ENOG4105KJM monovalent cation h antiporter subunit g AT706_02915 ENOG4105SC1 monovalent cation H antiporter subunit E AT706_02920 ENOG4108JPZ Monovalent cation H antiporter subunit D AT706_02925 ENOG4108ZE9 Monovalent cation H antiporter subunit C AT706_02930 ENOG4105HC0 Na H antiporter AT706_02935 ENOG4105D65 subunit l AT706_02955 ENOG4105UIB (ABC) transporter AT706_02960 ENOG4108JQ9 ABC transporter AT706_02965 ENOG4105DIH basic membrane AT706_02970 ENOG4108MRH transcriptional regulatory protein AT706_02985 ENOG4105KIR Thiol-disulfide oxidoreductase dcc AT706_02990 ENOG4105BZ4 penicillin-binding protein AT706_03010 ENOG4105Y38 Kinase-associated protein B AT706_03015 ENOG4108HGU Histidine kinase AT706_03020 ENOG4105C87 Aminotransferase class I and II AT706_03030 ENOG4108MUZ hydrolase AT706_03035 ENOG4108ZB6 transcriptional regulator AsnC family AT706_03040 ENOG4105CHM Aminotransferase AT706_03050 ENOG4105WG9 Conserved Protein AT706_03055 ENOG4107QW4 alcohol dehydrogenase AT706_03065 ENOG4107QYV phosphohexose isomerase AT706_03080 ENOG4107PBV potassium channel AT706_03085 ENOG4107PBV potassium channel AT706_03100 ENOG4105C37 (CBS) domain AT706_03110 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme AT706_03125 ENOG4105C8Q Methyl-accepting chemotaxis AT706_03130 ENOG4105C8Q Methyl-accepting chemotaxis AT706_03135 ENOG4105C8Q Methyl-accepting chemotaxis AT706_03140 ENOG4105C8Q Methyl-accepting chemotaxis AT706_03155 ENOG4105E98 transcriptional regulator DeoR family AT706_03160 ENOG4105DET Rhamnulokinase AT706_03165 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) AT706_03170 ENOG4105DKG l-rhamnose isomerase AT706_03175 ENOG4105EE0 oxidoreductase AT706_03185 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) AT706_03205 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj AT706_03210 ENOG4107I77 yiaA/B two helix domain AT706_03215 ENOG4105CZN Potassium uptake protein AT706_03230 ENOG4105TRT Transcriptional regulator AT706_03235 ENOG4105C26 Dehydrogenase AT706_03240 ENOG4108JB8 alcohol dehydrogenase AT706_03245 ENOG4108VNY MOSC domain protein AT706_03250 ENOG4106DF1 AT706_03260 ENOG4105DZ6 Band 7 protein AT706_03265 ENOG4105VRR gCN5-related N-acetyltransferase AT706_03270 ENOG4105VRR gCN5-related N-acetyltransferase AT706_03275 ENOG4105N67 Proton-coupled thiamine transporter YuaJ AT706_03410 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) AT706_03420 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) AT706_03435 ENOG4108KS4 Spore coat protein AT706_03440 ENOG4107SBE Glycosyl transferase (Group 1 AT706_03455 ENOG4107SBE Glycosyl transferase (Group 1 AT706_03460 ENOG4108IAJ Nad-dependent epimerase dehydratase AT706_03480 ENOG4105E4F Isochorismate synthase AT706_03485 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) AT706_03490 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) AT706_03495 ENOG4108IPT Naphthoate synthase AT706_03500 ENOG4105CEY Amp-dependent synthetase and ligase AT706_03505 ENOG4105DTQ mandelate racemase muconate lactonizing AT706_03510 ENOG4105DSE periplasmic solute binding protein AT706_03515 ENOG4105DIK (ABC) transporter AT706_03520 ENOG4105CC5 ABC transporter AT706_03525 ENOG4105CC5 ABC transporter AT706_03550 ENOG4108V2W Carbonate dehydratase AT706_03555 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) AT706_03560 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) AT706_03575 ENOG4108RMU ferritin dps family protein AT706_03590 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component AT706_03600 ENOG4105D2X ABC transporter substrate-binding protein AT706_03615 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase AT706_03620 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP AT706_03625 ENOG4105CAQ asparagine synthetase AT706_03630 ENOG4105C85 amino acid AT706_03635 ENOG4108Z0R Transferase AT706_03640 ENOG4105E8V Alpha Beta Hydrolase Fold protein AT706_03655 ENOG4105N5T Radical SAM Protein AT706_03670 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family AT706_03675 ENOG4105DVE abc transporter atp-binding protein AT706_03690 ENOG4105C19 ABC transporter AT706_03695 ENOG4107R34 abc transporter permease protein AT706_03705 ENOG4105EWM Histidine kinase AT706_03710 ENOG4105C19 ABC transporter AT706_03720 ENOG4106UBQ AT706_03725 ENOG410605W Major Facilitator AT706_03730 ENOG4105BZU Histidine kinase AT706_03740 ENOG4105C8T Leucyl-tRNA synthetase AT706_03745 ENOG41085GJ domain protein AT706_03755 ENOG4105I1K ABC transporter AT706_03760 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component AT706_03775 ENOG4105NTD Inherit from COG: Hydrolase AT706_03785 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AT706_03790 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AT706_03800 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) AT706_03805 ENOG4106A3M Cytochrome p-450 AT706_03815 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component AT706_03825 ENOG41075H3 AraC family transcriptional regulator AT706_03835 ENOG4105F5H Glycosyl Hydrolase Family 88 AT706_03845 ENOG4105DDC Oxidoreductase domain protein AT706_03850 ENOG4105MU9 integral membrane protein AT706_03860 ENOG4105C94 Transporter AT706_03865 ENOG4105CBX hi0933 family AT706_03880 ENOG4105YW5 deoR family transcriptional regulator AT706_03895 ENOG4105C7N Xanthine uracil vitamin C permease AT706_03900 ENOG4107QSE Dipeptidase AT706_03905 ENOG4105C6T cysteine synthase AT706_03910 ENOG4107F58 2'-5' rna ligase AT706_03925 ENOG4108IUM Glycogen debranching enzyme AT706_03930 ENOG4108V15 phosphotransferase enzyme family AT706_03940 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) AT706_03945 ENOG4105C8F Beta-lactamase domain protein AT706_03950 ENOG4105C6K Malic enzyme AT706_03965 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ AT706_03980 ENOG4108VDD TRNA binding domain protein AT706_03990 ENOG4105DFU Cell wall formation (By similarity) AT706_04010 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase AT706_04015 ENOG4105ETE Transcriptional regulator (LacI family AT706_04020 ENOG4107R0U MotA TolQ exbB proton channel AT706_04025 ENOG4105ER2 Ompa motb domain protein AT706_04030 ENOG4105DGU Histone deacetylase AT706_04035 ENOG4105W87 Cbs domain AT706_04040 ENOG4105F1V Acetoin utilization protein AT706_04050 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AT706_04060 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) AT706_04065 ENOG4105BZU Histidine kinase AT706_04075 ENOG4105U5Y Transcriptional regulator AT706_04110 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) AT706_04115 ENOG4105EFZ amidohydrolase AT706_04120 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AT706_04125 ENOG4105D07 Signal peptide peptidase, SppA AT706_04130 ENOG4105VK3 rdd domain containing protein AT706_04140 ENOG4105KBJ sporulation protein ytfj AT706_04145 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AT706_04155 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) AT706_04160 ENOG4105EPU Molybdenum cofactor synthesis domain protein AT706_04165 ENOG4105CDH Citrulline--aspartate ligase AT706_04170 ENOG4105CH7 arginosuccinase AT706_04185 ENOG4105E8R UPF0173 metal-dependent hydrolase AT706_04190 ENOG4108KSA LysR family transcriptional regulator AT706_04195 ENOG4108XSB acetyltransferase, (GNAT) family AT706_04220 ENOG4105CDA abc transporter atp-binding protein AT706_04225 ENOG4105DEN Luciferase family AT706_04245 ENOG4105CH2 amidohydrolase AT706_04250 ENOG410635A Membrane AT706_04270 ENOG4105SFS phosphoesterase RecJ domain protein AT706_04275 ENOG4106EVM AT706_04285 ENOG4105VV2 AT706_04290 ENOG4105C0B DNA polymerase III (alpha subunit) AT706_04295 ENOG4105C6K Malic enzyme AT706_04300 ENOG4108IEY Carboxyl transferase domain AT706_04310 ENOG4105CTQ phosphohexokinase AT706_04315 ENOG4105CA9 Pyruvate kinase AT706_04320 ENOG4105FS0 cytoplasmic membrane protein AT706_04325 ENOG4108REF Sporulation integral membrane protein ytvi AT706_04335 ENOG4105BZN citrate synthase AT706_04340 ENOG4108HMX isocitrate dehydrogenase (NADP) AT706_04345 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AT706_04350 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AT706_04355 ENOG4105BZU Histidine kinase AT706_04360 ENOG4105C2M dna polymerase I AT706_04365 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) AT706_04380 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) AT706_04385 ENOG4105CV8 reductase AT706_04390 ENOG4105F27 Major Facilitator AT706_04395 ENOG4105KVH Transcriptional regulator AT706_04400 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase AT706_04405 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) AT706_04410 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) AT706_04430 ENOG4108TDW sporulation protein YtxC AT706_04435 ENOG4105C22 threonyL-tRNA synthetase AT706_04440 ENOG4105U0R haloacid dehalogenase-like hydrolase AT706_04445 ENOG4108HRK Histidine kinase AT706_04450 ENOG4105DY9 regulatoR AT706_04460 ENOG41067MG lrgb family AT706_04470 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) AT706_04475 ENOG4105VJV 50s ribosomal protein L35 AT706_04480 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) AT706_04485 ENOG410696E Membrane AT706_04495 ENOG4105CN9 Peptidase m42 family protein AT706_04500 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase AT706_04510 ENOG4105EF1 ribulokinase AT706_04515 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AT706_04525 ENOG4108MDK Dehydrogenase AT706_04540 ENOG4105DRS transport system, permease AT706_04545 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) AT706_04560 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AT706_04565 ENOG4105CQB FAD linked oxidase domain protein AT706_04575 ENOG41067MF small acid-soluble spore protein AT706_04580 ENOG4108RWN rrna methyltransferase AT706_04590 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) AT706_04595 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AT706_04600 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AT706_04615 ENOG4105DCG PHP domain protein AT706_04620 ENOG4105C98 muts2 protein AT706_04630 ENOG4105CEY Amp-dependent synthetase and ligase AT706_04635 ENOG4107Z3H Transcriptional regulator, TetR family AT706_04640 ENOG41060WC Enoyl-CoA hydratase AT706_04645 ENOG4105BZJ Electron transfer flavoprotein AT706_04650 ENOG4105C10 Electron transfer flavoprotein AT706_04655 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) AT706_04660 ENOG4105K63 Thioredoxin AT706_04665 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) AT706_04670 ENOG4105CFH Aspartokinase AT706_04685 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit AT706_04695 ENOG4105E33 succinate dehydrogenase AT706_04705 ENOG4105PFC Transcriptional regulator AT706_04710 ENOG41067TZ transcriptional regulator, MarR family AT706_04715 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AT706_04720 ENOG4108XJQ germination protein AT706_04725 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) AT706_04730 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AT706_04735 ENOG4105M59 Phosphodiesterase, mj0936 family AT706_04745 ENOG4107KM7 Heat induced stress protein YflT AT706_04755 ENOG4105I4A GCN5-related N-acetyltransferase AT706_04765 ENOG4105C7K acetolactate synthase AT706_04770 ENOG4108ZP8 Acetolactate synthase small subunit AT706_04775 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase AT706_04780 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) AT706_04785 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AT706_04790 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AT706_04795 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) AT706_04805 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation AT706_04810 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) AT706_04815 ENOG4108IUQ atp-dependent protease AT706_04820 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AT706_04825 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) AT706_04835 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) AT706_04845 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) AT706_04855 ENOG4105D52 delta-aminolevulinic acid dehydratase AT706_04860 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase AT706_04865 ENOG41068KH stage VI sporulation protein D AT706_04870 ENOG4106AR7 Spore coat protein AT706_04880 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AT706_04885 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AT706_04890 ENOG4106A3R peptidase AT706_04900 ENOG4108Z03 MAF-like protein AT706_04905 ENOG4105W5Q DNA repair protein (RadC AT706_04910 ENOG4105DFF Rod shape-determining protein mreb AT706_04915 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AT706_04920 ENOG4105YHC Rod shape-determining protein MreD AT706_04925 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) AT706_04930 ENOG4107QMS site-determining protein AT706_04945 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) AT706_04950 ENOG4105X36 (ribosomal) protein AT706_04955 ENOG4105K46 50S ribosomal protein l27 AT706_04970 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control AT706_04975 ENOG41090I5 UPF0735 ACT domain-containing protein AT706_04980 ENOG4105CQC Prephenate dehydratase AT706_04995 ENOG4108IYU L-aspartate oxidase AT706_05000 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AT706_05005 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) AT706_05010 ENOG4106678 morphogenetic protein associated with SpoVID AT706_05020 ENOG4105CDY transcriptional regulatory protein AT706_05025 ENOG4105BZG amino acid carrier protein AT706_05050 ENOG4105CK5 oxidoreductase AT706_05055 ENOG4105IE8 Alpha-ketoglutarate permease AT706_05065 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) AT706_05070 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) AT706_05075 ENOG41061AI Protein of unknown function (DUF2905) AT706_05080 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) AT706_05085 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) AT706_05090 ENOG4105VIE preprotein translocase, subunit YajC AT706_05095 ENOG4105NAP AT706_05100 ENOG4108QG2 Membrane AT706_05105 ENOG4105CKP Polysaccharide Biosynthesis Protein AT706_05115 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AT706_05120 ENOG4105NCW Trka-c domain protein AT706_05125 ENOG41067VP Protein of unknown function (DUF1049) AT706_05130 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AT706_05135 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) AT706_05140 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AT706_05150 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AT706_05160 ENOG4105CUT histidyl-tRNA synthetase AT706_05165 ENOG4105C9M aspartyl-trna synthetase AT706_05175 ENOG4105CUZ uba thif-type nad fad binding protein AT706_05180 ENOG4105D1H recombination factor protein RarA AT706_05190 ENOG4105C3J Cysteine desulfurase AT706_05195 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) AT706_05205 ENOG4105C7H Helicase, RecD TraA family AT706_05215 ENOG41060CR AT706_05225 ENOG4105DRP amino acid AbC transporter AT706_05230 ENOG4105EAD ABC transporter AT706_05235 ENOG4105CT1 (ABC) transporter AT706_05240 ENOG4105CDA abc transporter atp-binding protein AT706_05245 ENOG4105C02 permease AT706_05250 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) AT706_05255 ENOG4105VBH UPF0297 protein AT706_05260 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) AT706_05265 ENOG4105VPH UPF0473 protein AT706_05270 ENOG4105HHA aminodeoxychorismate lyase AT706_05275 ENOG4108VQJ O-methyltransferase AT706_05280 ENOG4105XYU peptidase (U32 family) AT706_05285 ENOG4105CFP Peptidase U32 AT706_05290 ENOG4105DBI uridine monophosphokinase AT706_05295 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) AT706_05300 ENOG4107XRG penicillin-binding protein AT706_05315 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) AT706_05330 ENOG4105C28 cystathionine AT706_05345 ENOG4108JB9 formate dehydrogenase AT706_05350 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) AT706_05355 ENOG4105TMB Formate nitrite transporter AT706_05375 ENOG41082JN Transcriptional regulator AT706_05380 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AT706_05385 ENOG4105WDR AT706_05390 ENOG4105EXC Acyl-transferase AT706_05395 ENOG4108P49 AntiSigma factor AT706_05400 ENOG4105JVQ RNA Polymerase AT706_05405 ENOG4108NGU Transcriptional regulator AT706_05410 ENOG4105N14 lysine exporter protein LysE YggA AT706_05415 ENOG4105C85 amino acid AT706_05420 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AT706_05425 ENOG4105YHU PTS system AT706_05430 ENOG4108IQ3 PTS system AT706_05435 ENOG4105ETZ PTS System AT706_05440 ENOG4105F3R pts system mannose fructose sorbose family iid AT706_05445 ENOG4108HKT sucrose-6-phosphate hydrolase AT706_05450 ENOG4108Z0Z intracellular protease Pfpi family AT706_05455 ENOG4105DQ4 alcohol dehydrogenase AT706_05465 ENOG4105VUF Transcriptional regulator AT706_05480 ENOG4105E2A Dehydrogenase AT706_05485 ENOG4105PGS Spore coat protein AT706_05495 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase AT706_05500 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein AT706_05505 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein AT706_05510 ENOG4108VQT Alpha beta hydrolase fold protein AT706_05515 ENOG4105X5K response regulator receiver protein AT706_05520 ENOG41083Q9 chitosanase AT706_05525 ENOG4105CPC Aldo Keto reductase AT706_05530 ENOG410904A RNA polymerase AT706_05535 ENOG4108MEK Metal-binding protein YodA AT706_05550 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) AT706_05555 ENOG4105EA8 2-Nitropropane dioxygenase AT706_05560 ENOG41075D4 Aminoglycoside 6-adenylyltransferase AT706_05570 ENOG41064BW Protein of unknown function (DUF2568) AT706_05600 ENOG4108ZRZ Transcriptional regulator (AsnC family) AT706_05605 ENOG4108UMN azlc family AT706_05610 ENOG4105KMT branched-chain amino acid AT706_05630 ENOG41090U3 tautomerase AT706_05635 ENOG4105PGM cation diffusion facilitator family transporter AT706_05640 ENOG4105H3G oxidoreductase AT706_05645 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family AT706_05660 ENOG4105C37 (CBS) domain AT706_05675 ENOG41090E6 transcriptional regulator MERR family AT706_05715 ENOG41082J7 Rhodanese domain protein AT706_05720 ENOG41067TZ transcriptional regulator, MarR family AT706_05725 ENOG41068VA AT706_05730 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AT706_05745 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) AT706_05790 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr AT706_05800 ENOG4108UYN gCN5-related N-acetyltransferase AT706_05810 ENOG4105DHF Membrane AT706_05815 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AT706_05820 ENOG4108SWU Histidine kinase AT706_05835 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AT706_05840 ENOG4105WFK nuclease AT706_05855 ENOG41080BT SNARE associated Golgi AT706_05860 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase AT706_05880 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase AT706_05885 ENOG4105CQW ribosome biogenesis GTPase YqeH AT706_05890 ENOG4105E2X shikimate dehydrogenase AT706_05895 ENOG410812S Rna-binding protein AT706_05900 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) AT706_05905 ENOG4108WF2 Metal Dependent Phosphohydrolase AT706_05915 ENOG4108D32 Methyltransferase AT706_05925 ENOG4105KQC Competence protein AT706_05930 ENOG4108UK2 deaminase AT706_05935 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 AT706_05945 ENOG4105TQK DNA polymerase iii, delta' subunit AT706_05950 ENOG41082YS Binds directly to 16S ribosomal RNA AT706_05955 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) AT706_05960 ENOG4108ZRV stage ii sporulation protein p AT706_05970 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) AT706_05975 ENOG4105CSA Coproporphyrinogen iii oxidase AT706_05980 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) AT706_05985 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ AT706_05990 ENOG4105CFG Acts as a chaperone (By similarity) AT706_06000 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) AT706_06005 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AT706_06010 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AT706_06025 ENOG4105KTH gatB Yqey AT706_06030 ENOG4105F7J membrane-bound serine protease AT706_06035 ENOG4105DI5 UPF0365 protein AT706_06045 ENOG41068P3 sporulation protein YqfC AT706_06050 ENOG4105EI1 sporulation protein yqfd AT706_06055 ENOG4105C9A Phoh family AT706_06065 ENOG4105CTJ Metal Dependent Phosphohydrolase AT706_06070 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) AT706_06075 ENOG4107YR5 Diacylglycerol kinase AT706_06080 ENOG4105KG3 cytidine deaminase AT706_06085 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) AT706_06095 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) AT706_06100 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit AT706_06105 ENOG4105C38 Glycyl-tRNA synthetase beta subunit AT706_06115 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) AT706_06120 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 AT706_06125 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AT706_06130 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AT706_06145 ENOG4105EGD dinuclear metal center protein, YbgI family AT706_06150 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) AT706_06165 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) AT706_06170 ENOG41069ZM Protein of unknown function (DUF2624) AT706_06175 ENOG4108JYZ YitT family AT706_06180 ENOG4105N80 Ferric uptake regulator, Fur family AT706_06185 ENOG4108U5J '-nucleotidase AT706_06190 ENOG41063Y9 AT706_06195 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) AT706_06210 ENOG4105SXS Protein of unknown function (DUF456) AT706_06215 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AT706_06225 ENOG4107RF6 penicillin-binding protein AT706_06230 ENOG4105CVA phosphate AT706_06235 ENOG4105C8U phosphate abc transporter AT706_06240 ENOG4105E2Z phosphate ABC transporter (Permease AT706_06245 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AT706_06250 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) AT706_06255 ENOG41068DG YceG-like family AT706_06275 ENOG4105WDJ 50S ribosomal protein L33 AT706_06280 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AT706_06290 ENOG4107ZXI Rhomboid family AT706_06305 ENOG4105E0M Sulfatase AT706_06330 ENOG4105C5X domain protein AT706_06355 ENOG4105C37 (CBS) domain AT706_06415 ENOG4105VFR signal peptidase AT706_06425 ENOG4108IMY Transcriptional regulator AT706_06440 ENOG4105C0D helicase AT706_06445 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) AT706_06450 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor AT706_06455 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor AT706_06460 ENOG4105WZW rhodanese family AT706_06465 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) AT706_06470 ENOG4105KST dependent repressor AT706_06485 ENOG4105CBJ Metal-dependent enzyme AT706_06495 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) AT706_06500 ENOG4105DC7 peptidase M24 AT706_06505 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) AT706_06515 ENOG4105CD2 stage iii sporulation protein aa AT706_06520 ENOG4105KR5 Stage iii sporulation protein AT706_06525 ENOG4108CQH stage III sporulation protein AC AT706_06530 ENOG4105KQ4 Stage iii sporulation protein ad AT706_06540 ENOG410644B Stage III sporulation protein af AT706_06560 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AT706_06565 ENOG4108ZSR alkaline shock protein AT706_06570 ENOG4105M7K Involved in the transcription termination process (By similarity) AT706_06575 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) AT706_06580 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AT706_06585 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) AT706_06590 ENOG4105CTB Polyprenyl synthetase AT706_06600 ENOG4105DX0 Hemolysin A AT706_06605 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) AT706_06610 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AT706_06615 ENOG4105S1Z Stage IV sporulation protein B AT706_06625 ENOG4107QQR Sporulation AT706_06635 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AT706_06650 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AT706_06655 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AT706_06665 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase AT706_06670 ENOG4105C1G acyl-Coa dehydrogenase AT706_06680 ENOG4105DXD 2-methylcitrate dehydratase AT706_06685 ENOG4105CR4 methylisocitrate lyase AT706_06690 ENOG4106CCJ Protein of unknown function (DUF2627) AT706_06695 ENOG4108JUB Transcriptional regulator AT706_06705 ENOG4107RDP Dehydrogenase AT706_06710 ENOG4105CKM Branched-chain carboxylic acid kinase AT706_06725 ENOG4105CPP Dehydrogenase, E1 component AT706_06730 ENOG4105C7S Dehydrogenase AT706_06745 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) AT706_06750 ENOG4108Y6J UPF0403 protein AT706_06755 ENOG4108HW3 (ABC) transporter AT706_06760 ENOG4105E5Q amino acid AbC transporter AT706_06765 ENOG4105CDA abc transporter atp-binding protein AT706_06770 ENOG4108QEG Membrane AT706_06775 ENOG4108VZI ErfK ybiS ycfS ynhG family protein AT706_06785 ENOG4108ZVT methylmalonyl-coA epimerase AT706_06790 ENOG4108HNZ carboxyl transferase AT706_06795 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AT706_06800 ENOG4108NA0 Uncharacterized conserved protein (COG2071) AT706_06805 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) AT706_06815 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AT706_06820 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AT706_06825 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AT706_06830 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) AT706_06835 ENOG410861F 50S ribosomal protein L33 AT706_06845 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AT706_06855 ENOG4105II7 pyrroline-5-carboxylate reductase AT706_06860 ENOG41069FQ Metallo-beta-lactamase superfamily AT706_06865 ENOG4108IXY short-chain dehydrogenase reductase AT706_06880 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase AT706_06890 ENOG4105E5W Transporter AT706_06900 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) AT706_06910 ENOG4108XET gCN5-related N-acetyltransferase AT706_06915 ENOG4105KAC Antibiotic biosynthesis monooxygenase AT706_06920 ENOG4105RHY Pfam:UPF0157 AT706_06925 ENOG4106HZJ AT706_06945 ENOG4105CPC Aldo Keto reductase AT706_06955 ENOG4108YZ4 nudix hydrolase AT706_06965 ENOG4108IMY Transcriptional regulator AT706_06970 ENOG4105HDK L-asparaginase AT706_06975 ENOG4108IJ0 Aspartate ammonia-lyase AT706_06980 ENOG4105DFD Na H antiporter AT706_06995 ENOG4105MZ9 stage II sporulation protein m AT706_07000 ENOG4105I3K Ferric uptake regulator, Fur family AT706_07010 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AT706_07015 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) AT706_07020 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) AT706_07025 ENOG4105DZ1 carboxypeptidase AT706_07030 ENOG41082AN stage II sporulation protein AT706_07035 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) AT706_07040 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AT706_07055 ENOG41090VF Stage v sporulation protein ac AT706_07060 ENOG4105CZ3 stage V sporulation protein ad AT706_07070 ENOG4105G6R Stage v sporulation protein ae AT706_07080 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) AT706_07085 ENOG4105PTM secreted protein AT706_07090 ENOG4107ZE5 PPIases accelerate the folding of proteins AT706_07100 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) AT706_07105 ENOG4105C3F Signal peptidase i AT706_07115 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AT706_07120 ENOG4108R6K riboflavin synthase, subunit alpha AT706_07125 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) AT706_07130 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) AT706_07145 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) AT706_07150 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) AT706_07160 ENOG4105DZ1 carboxypeptidase AT706_07165 ENOG4108JIC nucleoside recognition domain protein AT706_07175 ENOG4105FE9 pseudouridine synthase AT706_07185 ENOG4107TWT Cytochrome c biogenesis protein AT706_07190 ENOG4105CRE cytochrome C AT706_07195 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AT706_07200 ENOG4105BZU Histidine kinase AT706_07215 ENOG4105FF2 Type I DHQase AT706_07220 ENOG4108JQ1 Dehydrogenase AT706_07230 ENOG4108SAX Membrane AT706_07240 ENOG4105T7X AT706_07245 ENOG4105C9U ATP-dependent DNA helicase RecQ AT706_07250 ENOG4105I7S Abortive infection protein AT706_07265 ENOG4107RGJ metallophosphoesterase AT706_07280 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase AT706_07285 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) AT706_07295 ENOG4105MSI germination protein ypeb AT706_07310 ENOG4105CAT Cytidine monophosphate kinase AT706_07315 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AT706_07320 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) AT706_07335 ENOG4105S2F AT706_07340 ENOG41065D1 AT706_07345 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) AT706_07350 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase AT706_07365 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) AT706_07370 ENOG4105K70 DNA-binding protein AT706_07375 ENOG4105EUJ GTP cyclohydrolase i AT706_07385 ENOG4105XXQ heptaprenyl diphosphate synthase component I AT706_07390 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) AT706_07395 ENOG4105EAH synthase AT706_07400 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) AT706_07410 ENOG4105BZU Histidine kinase AT706_07415 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase AT706_07420 ENOG4105D49 3-dehydroquinate synthase AT706_07425 ENOG4105KHN chorismate mutase AT706_07430 ENOG4105CRQ synthase (Component I) AT706_07435 ENOG4108I0Q anthranilate phosphoribosyltransferase AT706_07445 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase AT706_07450 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) AT706_07460 ENOG4105CIH Imidazole acetol-phosphate transaminase AT706_07470 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase AT706_07475 ENOG41068YB TPR repeat-containing protein AT706_07495 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) AT706_07515 ENOG4108JYZ YitT family AT706_07520 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase AT706_07525 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) AT706_07530 ENOG4108Z5K methylglyoxal synthase AT706_07535 ENOG4105FJR Lmbe family AT706_07540 ENOG4105CPK Glycosyl transferase (Group 1 AT706_07545 ENOG4105DJ0 Poly(A) Polymerase AT706_07550 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase AT706_07555 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) AT706_07560 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) AT706_07565 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) AT706_07570 ENOG4105DVT helicase AT706_07575 ENOG4105YAC AT706_07585 ENOG4105CHM Aminotransferase AT706_07590 ENOG4105C5S asparaginyl-tRNA synthetase AT706_07600 ENOG4105CSM endonuclease III AT706_07610 ENOG4105BZ4 penicillin-binding protein AT706_07660 ENOG4108I5C dEAD DEAH box helicase AT706_07665 ENOG4107X2U Inherit from COG: Exonuclease-like protein AT706_07675 ENOG4108UKS UPF0398 protein AT706_07685 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) AT706_07695 ENOG4105DVT helicase AT706_07700 ENOG4105CHR reductase AT706_07710 ENOG4108M60 Transcriptional regulator AT706_07715 ENOG4105D7K pfkb domain protein AT706_07720 ENOG4108UHU Aldolase AT706_07725 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) AT706_07730 ENOG4105CTD carboxy-peptidase AT706_07735 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) AT706_07740 ENOG4105C2W permease AT706_07745 ENOG41065KQ synthase AT706_07755 ENOG410890F Dynamin family AT706_07785 ENOG41081VK Ribonuclease AT706_07825 ENOG4105CVG Homoserine O-transsuccinylase AT706_07830 ENOG4108V06 Glutathione peroxidase AT706_07850 ENOG4105C01 Dihydroxy-acid dehydratase AT706_07855 ENOG4108Y6J UPF0403 protein AT706_07860 ENOG4107YX5 Pfam:DUF548 AT706_07875 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) AT706_07880 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) AT706_07890 ENOG4108UT2 hemolysin iii AT706_07900 ENOG4105C7B Threonine dehydratase AT706_07915 ENOG4108KF3 Electron transport protein SCO1 SenC AT706_07920 ENOG41090WU lipolytic protein G-D-S-L family AT706_07925 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) AT706_07945 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) AT706_07950 ENOG4105E0X reductase AT706_07955 ENOG4105C5E polysaccharide biosynthesis protein AT706_07960 ENOG4107T32 3-phytase (EC 3.1.3.8) AT706_08000 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AT706_08015 ENOG4107S4Y M20 DapE family protein YgeY AT706_08020 ENOG4108TSC N-acetyltransferase AT706_08025 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AT706_08060 ENOG410841Q phosphoesterase PA-phosphatase related protein AT706_08065 ENOG4106Z5R AT706_08075 ENOG4105D3A purine nucleoside phosphorylase DeoD-type AT706_08080 ENOG4108VXD carboxy-peptidase AT706_08100 ENOG4105E1V na solute symporter AT706_08115 ENOG4105FBA Phospholipase Carboxylesterase AT706_08130 ENOG41090U3 tautomerase AT706_08135 ENOG4105C6Z Gluconate AT706_08150 ENOG4105FR1 rard protein AT706_08170 ENOG4106SCS STAS domain AT706_08175 ENOG4107QMU Mate efflux family protein AT706_08185 ENOG41087PP glycosyltransferase MGT family AT706_08190 ENOG4105K4H Nlp p60 protein AT706_08200 ENOG4105GMT ATPase associated with various cellular activities aaa_5 AT706_08205 ENOG4107T89 von Willebrand factor, type A AT706_08215 ENOG4105C7S Dehydrogenase AT706_08220 ENOG4105C09 Bile acid AT706_08225 ENOG4105C8J )-transporter AT706_08230 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AT706_08235 ENOG4105EWU Squalene--hopene cyclase AT706_08240 ENOG4105C26 Dehydrogenase AT706_08280 ENOG4105SCY DNAK suppressor AT706_08285 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) AT706_08295 ENOG4105C9U ATP-dependent DNA helicase RecQ AT706_08300 ENOG41069ER domain protein AT706_08305 ENOG4108S01 response regulator AT706_08310 ENOG4108ZGX Histidine kinase AT706_08315 ENOG4105ECK Fatty Acid Desaturase AT706_08335 ENOG4108SJC Membrane AT706_08345 ENOG4105KTU Transcriptional regulator, arsr family AT706_08355 ENOG4105D29 Helix-turn-helix type 11 domain protein AT706_08365 ENOG4108W8B Beta-lactamase domain protein AT706_08375 ENOG4108HJF gCN5-related N-acetyltransferase AT706_08380 ENOG4105FTV AraC Family Transcriptional Regulator AT706_08385 ENOG4108Z7R Chaperone CsaA AT706_08400 ENOG4106BHF AT706_08405 ENOG4106ANW SMI1_KNR4 AT706_08430 ENOG4108J9Q DNA ligase AT706_08435 ENOG4107T94 Endo-14-beta-xylanase AT706_08440 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) AT706_08460 ENOG4108J4B Beta-lactamase AT706_08465 ENOG4108V4B ThiJ pfpI AT706_08475 ENOG4108Q5Y Membrane AT706_08485 ENOG4105NX3 Membrane AT706_08490 ENOG4105VMP Transcriptional regulator AT706_08500 ENOG41073R8 VanW family AT706_08520 ENOG4105F0F Oxalate decarboxylase AT706_08530 ENOG4108RAV Conserved protein AT706_08535 ENOG4108NR7 pectate lyase AT706_08540 ENOG4105XPP Protein of unknown function (DUF1275) AT706_08545 ENOG4108YQE rare lipoprotein a AT706_08555 ENOG4105EC8 Methyl-accepting chemotaxis AT706_08580 ENOG4108J2R molybdopterin oxidoreductase AT706_08585 ENOG4108M3J Dehydrogenase AT706_08590 ENOG4107U6E carbohydrate kinase FGGY AT706_08595 ENOG4105IE8 Alpha-ketoglutarate permease AT706_08600 ENOG41068WN AT706_08605 ENOG4108UB7 AT706_08625 ENOG4105II7 pyrroline-5-carboxylate reductase AT706_08630 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AT706_08635 ENOG4105C5Q Transcriptional regulator AT706_08640 ENOG4105CBC glutamate synthase AT706_08645 ENOG4105BZ8 glutamate synthase AT706_08650 ENOG4105CB2 alcohol dehydrogenase AT706_08655 ENOG4105SKE transcriptional Regulator LysR family AT706_08660 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) AT706_08685 ENOG4107QJQ Mate efflux family protein AT706_08690 ENOG4108N2V aldose 1-epimerase AT706_08695 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family AT706_08700 ENOG4105C0W non-ribosomal peptide synthetase AT706_08710 ENOG4105C0W non-ribosomal peptide synthetase AT706_08715 ENOG4105CEY Amp-dependent synthetase and ligase AT706_08725 ENOG4106U2H Protein of unknown function (DUF1360) AT706_08730 ENOG4105F32 YngK protein AT706_08745 ENOG4105C1G acyl-Coa dehydrogenase AT706_08750 ENOG4105CEY Amp-dependent synthetase and ligase AT706_08755 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AT706_08760 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit AT706_08765 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase AT706_08770 ENOG4105E39 Enoyl-CoA hydratase AT706_08775 ENOG4107QX3 carboxylase AT706_08785 ENOG4107T5V SNARE associated Golgi AT706_08790 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AT706_08800 ENOG4107SYN Glycosyl hydrolases family 43 AT706_08805 ENOG4108MYR Secreted protein AT706_08820 ENOG4107QWR cellulase (EC 3.2.1.4) AT706_08845 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AT706_08850 ENOG4105K4P CoA-binding domain protein AT706_08855 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) AT706_08860 ENOG4105W8X HesB YadR YfhF-family protein AT706_08865 ENOG4105MI2 AT706_08875 ENOG41067CD Small, acid-soluble spore protein Tlp AT706_08890 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AT706_08895 ENOG4108I0Z Aconitate hydratase AT706_08905 ENOG4107DZX Small, acid-soluble spore protein P AT706_08930 ENOG4107QIV Cytochrome c biogenesis protein AT706_08950 ENOG4105CV1 Transketolase (EC 2.2.1.1) AT706_08955 ENOG4105VPS UPF0291 protein AT706_08960 ENOG4108SVB resolvase AT706_08970 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) AT706_08980 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) AT706_08990 ENOG4105K7W phage-related replication protein AT706_09000 ENOG4105FVX AT706_09015 ENOG4108NHD germination protein AT706_09020 ENOG4108Q8B Spore germination protein AT706_09085 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) AT706_09095 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) AT706_09105 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AT706_09110 ENOG4105C54 Major Facilitator superfamily AT706_09115 ENOG4107Y9E nuclease AT706_09120 ENOG4105CMG Carbohydrate kinase AT706_09125 ENOG4105C93 Xylose Isomerase AT706_09130 ENOG4105E2R ROK family AT706_09135 ENOG4105DSG hydrolase family 43 AT706_09140 ENOG4105CT4 transporter AT706_09170 ENOG4107NTZ AT706_09215 ENOG41079P0 AT706_09240 ENOG4105C5F glutamine synthetase AT706_09245 ENOG4105KV4 Transcriptional regulator AT706_09250 ENOG4105CXI aluminum resistance protein AT706_09255 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AT706_09265 ENOG4106F1P AAA ATPase, central domain protein AT706_09270 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AT706_09275 ENOG4105U6W MutT NUDIX family protein AT706_09280 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AT706_09285 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AT706_09290 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) AT706_09305 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) AT706_09310 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) AT706_09330 ENOG410814C multidrug resistance protein AT706_09335 ENOG4108X3M OsmC Ohr family protein AT706_09340 ENOG4105K7W phage-related replication protein AT706_09350 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin AT706_09365 ENOG4106A3M Cytochrome p-450 AT706_09375 ENOG4105C0W non-ribosomal peptide synthetase AT706_09385 ENOG4107SQU synthase AT706_09390 ENOG4105C0W non-ribosomal peptide synthetase AT706_09395 ENOG4108KQ6 Enoyl-CoA hydratase AT706_09400 ENOG4108MGH Enoyl-CoA hydratase AT706_09405 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase AT706_09410 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase AT706_09415 ENOG41062T2 Acyl carrier protein AT706_09420 ENOG4107QKG PfaD family AT706_09430 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AT706_09440 ENOG4108151 Beta-lactamase domain protein AT706_09445 ENOG4105W1N transcriptional regulator AT706_09450 ENOG4105IIP Membrane AT706_09460 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AT706_09465 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) AT706_09480 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AT706_09485 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AT706_09495 ENOG4105MCT stage V sporulation protein S AT706_09500 ENOG4105D48 metallophosphoesterase AT706_09505 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) AT706_09510 ENOG4108A04 Beta-lactamase AT706_09520 ENOG4105CEV competence damage-inducible protein AT706_09525 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase AT706_09540 ENOG4105XZV Protein of unknown function (DUF3243) AT706_09545 ENOG4108RKS Short-chain dehydrogenase reductase Sdr AT706_09565 ENOG4105FDP GntR family transcriptional regulator AT706_09570 ENOG4105CNU cell division protein FtsK AT706_09580 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit AT706_09590 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) AT706_09600 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AT706_09605 ENOG4108S0H Dipicolinic acid synthetase, b subunit AT706_09610 ENOG4105E35 Dipicolinate synthase subunit A AT706_09625 ENOG4105C1V Peptidase, M16 AT706_09635 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) AT706_09640 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) AT706_09645 ENOG4105DTN riboflavin biosynthesis protein ribF AT706_09650 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) AT706_09655 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) AT706_09660 ENOG4105W7A Protein of unknown function (DUF503) AT706_09665 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) AT706_09670 ENOG4105VHM ribosomal protein AT706_09675 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination AT706_09680 ENOG4105CHV Transcription elongation factor NusA AT706_09685 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) AT706_09690 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) AT706_09695 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) AT706_09700 ENOG4105DZP Membrane-associated zinc metalloprotease AT706_09710 ENOG4105KNE Phosphatidate cytidylyltransferase AT706_09715 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) AT706_09720 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) AT706_09730 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) AT706_09735 ENOG4105CE9 30S ribosomal protein S2 AT706_09745 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AT706_09760 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis AT706_09765 ENOG4105CBS Chea signal transduction histidine kinase AT706_09770 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) AT706_09780 ENOG4105FZW flagellar biosynthesis regulator FlhF AT706_09785 ENOG4105D7B Flagellar biosynthesis protein flha AT706_09790 ENOG4105D00 flagellar biosynthetic protein flhB AT706_09795 ENOG4105D19 Role in flagellar biosynthesis (By similarity) AT706_09800 ENOG4105VS8 Flagellar biosynthetic protein fliq AT706_09805 ENOG4105CN7 Flagellar biosynthetic protein FliP AT706_09815 ENOG4107YTP response regulator receiver protein AT706_09820 ENOG4105DD5 Flagellar motor switch protein AT706_09825 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AT706_09835 ENOG41068WV flagellar FlbD family protein AT706_09840 ENOG4108JQA flagellar AT706_09845 ENOG410822I Flagellar hook capping protein AT706_09850 ENOG410696Y Flagellar hook-length control protein AT706_09860 ENOG4106YF4 Flagellar biosynthesis chaperone AT706_09875 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AT706_09880 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AT706_09885 ENOG4105VQ0 flagellar hook-basal body complex protein fliE AT706_09890 ENOG4108ZC9 flagellar basal-body rod protein flgc AT706_09895 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AT706_09905 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) AT706_09910 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) AT706_09915 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AT706_09920 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) AT706_09925 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AT706_09930 ENOG4105C79 DNA protecting protein DprA AT706_09935 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AT706_09940 ENOG4105CMV Succinyl-CoA synthetase subunit beta AT706_09945 ENOG4105VM1 flagellar AT706_09955 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) AT706_09960 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) AT706_09965 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) AT706_09970 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) AT706_09975 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) AT706_09985 ENOG4108BW8 UPF0109 protein AT706_09990 ENOG4105K5M 30s ribosomal protein S16 AT706_10000 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) AT706_10010 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) AT706_10015 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) AT706_10020 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) AT706_10025 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) AT706_10030 ENOG4105CHR reductase AT706_10035 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AT706_10045 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) AT706_10050 ENOG4105CB5 ATP-dependent DNA helicase recG AT706_10055 ENOG4105EJQ L-serine dehydratase AT706_10065 ENOG4105DP4 dak2 domain fusion protein ylov AT706_10070 ENOG4108ZAA Alkaline-shock protein AT706_10075 ENOG4105VB9 50S ribosomal protein l28 AT706_10085 ENOG4105FJ0 thiamine AT706_10090 ENOG4105DJV ribulose-phosphate 3-epimerase AT706_10095 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) AT706_10100 ENOG4105D9P serine threonine protein kinase AT706_10105 ENOG4108ZF3 Phosphatase AT706_10110 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs AT706_10115 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B AT706_10120 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) AT706_10125 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AT706_10130 ENOG4105C25 Primosomal protein n' AT706_10135 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AT706_10145 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) AT706_10150 ENOG4105KC4 UPF0296 protein AT706_10155 ENOG4105DSJ YicC domain protein AT706_10165 ENOG4105F23 Fibronectin-binding protein AT706_10170 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein AT706_10175 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein AT706_10180 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AT706_10185 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) AT706_10190 ENOG4107S4M Sulfate adenylate transferase AT706_10200 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) AT706_10210 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) AT706_10215 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) AT706_10220 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) AT706_10225 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) AT706_10230 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AT706_10235 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AT706_10245 ENOG4105CXT aspartate transcarbamylase AT706_10255 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) AT706_10260 ENOG4105C34 Pseudouridine synthase AT706_10265 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) AT706_10275 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) AT706_10285 ENOG4105DBK s4 domain protein AT706_10290 ENOG41067XK integral membrane protein AT706_10295 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) AT706_10300 ENOG4105DFA alanine racemase domain protein AT706_10305 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AT706_10310 ENOG4105WR5 sporulation protein, YlmC YmxH family AT706_10320 ENOG4105DKW ABC transporter AT706_10330 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AT706_10335 ENOG4105FFI sigma-e processing peptidase spoiiga AT706_10345 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AT706_10350 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AT706_10355 ENOG4105K67 small basic protein AT706_10365 ENOG4108R2U division initiation protein AT706_10370 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) AT706_10375 ENOG4105D4A Cell wall formation (By similarity) AT706_10380 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) AT706_10385 ENOG4105CNI cell division protein FtsW AT706_10390 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) AT706_10395 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) AT706_10405 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AT706_10415 ENOG4105CJN penicillin-binding protein AT706_10425 ENOG4105CJN penicillin-binding protein AT706_10435 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) AT706_10440 ENOG4108V6E Cell division protein mraZ AT706_10465 ENOG41067VY 50S ribosomal protein L32 AT706_10470 ENOG4105KNH Nucleic acid-binding protein AT706_10480 ENOG4105CDE UPF0348 protein AT706_10490 ENOG41063PX domain protein AT706_10495 ENOG4105D78 K07001 NTE family protein AT706_10500 ENOG4105H20 Sporulation integral membrane protein YlbJ AT706_10505 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) AT706_10510 ENOG4106H78 methyltransferase AT706_10515 ENOG4105WUC UPF0298 protein AT706_10535 ENOG4106UY4 Inherit from COG: Scp-like extracellular AT706_10540 ENOG41080XQ Signal transduction protein with cbs domains AT706_10555 ENOG41064X9 cytochrome C oxidase subunit IV AT706_10560 ENOG4105CCU oxidase (Subunit III) AT706_10565 ENOG4105BZ9 Cytochrome C oxidase, subunit I AT706_10575 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) AT706_10585 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) AT706_10590 ENOG4105CNI cell division protein FtsW AT706_10595 ENOG4105ZPI UPF0358 protein AT706_10600 ENOG4105CSV Glutaminase AT706_10610 ENOG4108IAB Phoh family AT706_10625 ENOG4105QA2 AT706_10630 ENOG4105CI3 gtp-binding protein typa AT706_10670 ENOG4105JQZ Methyltransferase AT706_10680 ENOG4105ECY inositol monophosphatase AT706_10695 ENOG4105WBI UPF0223 protein AT706_10700 ENOG4105CXN decarboxylase AT706_10710 ENOG4107QN2 dihydrolipoyl dehydrogenase AT706_10715 ENOG4105C7S Dehydrogenase AT706_10720 ENOG4105CPP Dehydrogenase, E1 component AT706_10740 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) AT706_10745 ENOG4108X4Q Hydrolase AT706_10755 ENOG4105CN5 Metallo-Beta-Lactamase AT706_10765 ENOG4107ZYR domain protein AT706_10775 ENOG4105BZU Histidine kinase AT706_10805 ENOG4105C5H ABC transporter AT706_10815 ENOG4105C3F Signal peptidase i AT706_10820 ENOG4105DM4 PTS System AT706_10825 ENOG4105DE4 1-phosphofructokinase AT706_10830 ENOG4105E98 transcriptional regulator DeoR family AT706_10835 ENOG4107RBB ABC transporter, permease AT706_10840 ENOG4105C19 ABC transporter AT706_10845 ENOG4107X8C Efflux transporter RND family MFP subunit AT706_10855 ENOG4105BZ1 (ABC) transporter AT706_10860 ENOG4105BZ1 (ABC) transporter AT706_10865 ENOG41067WU Molybdopterin converting factor (Subunit 1) AT706_10870 ENOG4108ZAF Molybdopterin AT706_10875 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein AT706_10880 ENOG4105CVM Molybdenum cofactor synthesis domain protein AT706_10885 ENOG4105D06 uba thif-type nad fad binding protein AT706_10890 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) AT706_10905 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AT706_10910 ENOG4105D3R alkyl hydroperoxide reductase AT706_10915 ENOG4105D8X mechanosensitive ion channel AT706_10925 ENOG4105CH2 amidohydrolase AT706_10935 ENOG4105NQC Flavodoxin AT706_10965 ENOG4108XRC Protein of unknown function (DUF458) AT706_10970 ENOG4107IN1 Protein of unknown function (DUF1797) AT706_10980 ENOG4105EPM Diguanylate phosphodiesterase AT706_10985 ENOG4105K6S Short-chain dehydrogenase reductase Sdr AT706_10995 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein AT706_11005 ENOG4105UIN AT706_11010 ENOG4107R88 Chemotaxis protein (CheV) AT706_11020 ENOG4105CHM Aminotransferase AT706_11025 ENOG4105BZU Histidine kinase AT706_11035 ENOG4105K4I Scp-like extracellular AT706_11040 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase AT706_11045 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer AT706_11055 ENOG4105F6S Spore photoproduct lyase AT706_11065 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AT706_11070 ENOG4105KRI phosphocarrier protein (HPr AT706_11080 ENOG4105CID antiterminator AT706_11095 ENOG4105DC7 peptidase M24 AT706_11105 ENOG4105C59 p-type ATPase AT706_11120 ENOG4105F0V Cell wall hydrolase AT706_11155 ENOG4105FEA Spore maturation protein AT706_11160 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) AT706_11165 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AT706_11170 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase AT706_11175 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) AT706_11180 ENOG4108K88 Membrane AT706_11190 ENOG4105E14 MotA TolQ exbB proton channel AT706_11195 ENOG4105ER2 Ompa motb domain protein AT706_11200 ENOG41090MY MarR family Transcriptional regulator AT706_11205 ENOG4105BZU Histidine kinase AT706_11225 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) AT706_11230 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) AT706_11235 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) AT706_11240 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit AT706_11250 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AT706_11255 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) AT706_11260 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) AT706_11270 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AT706_11275 ENOG4105BZU Histidine kinase AT706_11280 ENOG4108TGC Acyltransferase AT706_11300 ENOG4105D0M Protease HtpX homolog AT706_11310 ENOG410681C small acid-soluble spore protein AT706_11320 ENOG4108WZW RNA polymerase sigma AT706_11325 ENOG4107TS3 membrane protein, TerC AT706_11330 ENOG4107T5V SNARE associated Golgi AT706_11335 ENOG4105BZU Histidine kinase AT706_11340 ENOG4105FDF Could be involved in DNA repair (By similarity) AT706_11345 ENOG4105DQE DNA ligase AT706_11390 ENOG4105V75 Transcriptional regulator AT706_11395 ENOG4105CJW magnesium transporter AT706_11415 ENOG4106849 propeptide, pepSY amd peptidase M4 AT706_11425 ENOG41062D9 Histidine kinase AT706_11430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AT706_11435 ENOG4108X43 YKOF domain protein AT706_11440 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein AT706_11445 ENOG4108JJB ABC transporter AT706_11450 ENOG4108W7F transporter, permease AT706_11460 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin AT706_11465 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) AT706_11475 ENOG4107Y2X deaminase AT706_11480 ENOG4108ZHJ Organic hydroperoxide resistance protein AT706_11485 ENOG4105K56 Transcriptional regulator AT706_11500 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) AT706_11505 ENOG4105CIY formyltetrahydrofolate deformylase AT706_11510 ENOG41080TC multidrug resistance protein AT706_11520 ENOG4108428 Inherit from COG: -acetyltransferase AT706_11540 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AT706_11545 ENOG4108S4H thioesterase Superfamily protein AT706_11550 ENOG4107TUM Amidinotransferase AT706_11555 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) AT706_11560 ENOG4108JQ7 (ABC) transporter AT706_11565 ENOG4107SN7 NLP P60 protein AT706_11570 ENOG4105DTQ mandelate racemase muconate lactonizing AT706_11575 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A AT706_11585 ENOG4105C3U ABC transporter AT706_11590 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AT706_11595 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AT706_11600 ENOG4108ME1 Peptidase M55 D-aminopeptidase AT706_11610 ENOG4105C0H protease AT706_11620 ENOG4105CKK Glycosyl transferase, family 2 AT706_11625 ENOG4105EDW glycosyl transferase, family 39 AT706_11635 ENOG4107R7I amino acid AT706_11640 ENOG4107GRR phosphate transport regulator AT706_11645 ENOG4105CJ3 phosphate transporter AT706_11660 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase AT706_11690 ENOG41068G1 AT706_11700 ENOG410906S phage-like element pbsx protein xkdt AT706_11705 ENOG41066EA baseplate J family protein AT706_11710 ENOG4105MFU Protein of unknown function (DUF2634) AT706_11720 ENOG4105X7F AT706_11725 ENOG4108WZM domain protein AT706_11730 ENOG4108FKH Transglycosylase SLT domain AT706_11740 ENOG4105MTC XkdN-like protein AT706_11745 ENOG4105FR7 XkdM protein, phage-like element PBSX AT706_11750 ENOG4105PQS phage protein AT706_11765 ENOG41060SN AT706_11790 ENOG4108MDF Phage Portal Protein AT706_11795 ENOG4105IG6 Phage terminase, large subunit AT706_11800 ENOG4108TFU terminase (Small subunit) AT706_11850 ENOG410635T phage-like element pbsx protein AT706_11855 ENOG4105WEF catalase AT706_11860 ENOG4105K7W phage-related replication protein AT706_11865 ENOG4105KWG Pfam:DUF1696 AT706_11870 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase AT706_11875 ENOG41068K0 YCII-related domain AT706_11890 ENOG4105JD4 ATPase yjob AT706_11900 ENOG4107TSN permease AT706_11905 ENOG4105CTX dehydratase AT706_11910 ENOG4107QZW Altronate oxidoreductase AT706_11915 ENOG4107KJX Transcriptional regulator AT706_11920 ENOG4108I5G Major Facilitator superfamily AT706_11925 ENOG4105DMW Dehydrogenase reductase AT706_11930 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) AT706_11935 ENOG4105CPQ Dehydrogenase AT706_11940 ENOG4105DG4 malate L-lactate dehydrogenase AT706_11945 ENOG4105CT4 transporter AT706_11950 ENOG4105D2H Uronic isomerase AT706_11965 ENOG4105Q95 Cupin 2, conserved barrel domain protein AT706_11975 ENOG4108IXI (ABC) transporter AT706_11980 ENOG4105C4B ABC transporter, permease AT706_11985 ENOG4105EXQ uroporphyrinogen iii synthase hem4 AT706_11995 ENOG41087PP glycosyltransferase MGT family AT706_12000 ENOG4106A3M Cytochrome p-450 AT706_12025 ENOG4108IEG Formate dehydrogenase Alpha subunit AT706_12055 ENOG4107CUJ Protein of unknown function (DUF2690) AT706_12060 ENOG4108ZJ4 polysaccharide deacetylase AT706_12070 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) AT706_12085 ENOG4108Z66 YbaK ebsC protein AT706_12095 ENOG4105VMI -acetyltransferase AT706_12100 ENOG4105G7B Protein of unknown function (DUF2992) AT706_12105 ENOG4105DG6 mannose-6-phosphate isomerase AT706_12110 ENOG4105DM4 PTS System AT706_12175 ENOG4105JHY Membrane AT706_12180 ENOG4105D9U N-acetyltransferase AT706_12185 ENOG4105C28 cystathionine AT706_12190 ENOG4105C28 cystathionine AT706_12200 ENOG4108ZMI UPF0477 protein AT706_12215 ENOG4105ENA helicase AT706_12270 ENOG4107A88 AT706_12275 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH AT706_12280 ENOG4105DWF phosphomethylpyrimidine kinase AT706_12285 ENOG4105D06 uba thif-type nad fad binding protein AT706_12290 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) AT706_12305 ENOG4108VEU Thiamine monophosphate synthase AT706_12310 ENOG4105ETU transcriptional activator (TenA AT706_12325 ENOG4105EMS pseudouridine synthase AT706_12330 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AT706_12345 ENOG4105MIX Adenylate cyclase AT706_12350 ENOG4105E4C Lytic transglycosylase catalytic AT706_12355 ENOG4108Z18 K06886 hemoglobin AT706_12360 ENOG4105T58 Dithiol-disulfide isomerase AT706_12375 ENOG4105DPN Oligoendopeptidase f AT706_12385 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis AT706_12390 ENOG4108ZCF integral membrane protein AT706_12395 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) AT706_12410 ENOG4108JQ7 (ABC) transporter AT706_12420 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AT706_12425 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AT706_12430 ENOG4108J59 Extracellular solute-binding protein, family 5 AT706_12435 ENOG4105C31 Tryptophanyl-tRNA synthetase AT706_12445 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AT706_12460 ENOG4108JQ7 (ABC) transporter AT706_12465 ENOG4105C3U ABC transporter AT706_12475 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AT706_12480 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) AT706_12495 ENOG4107RMD Basic membrane lipoprotein AT706_12520 ENOG4105DBV ornithine carbamoyltransferase AT706_12530 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain AT706_12535 ENOG4105C8Y Acetylornithine aminotransferase AT706_12550 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AT706_12560 ENOG4105IQ5 FAD linked oxidase domain protein AT706_12570 ENOG4105VG1 fes assembly suf system protein AT706_12575 ENOG4108MXZ Esterase AT706_12580 ENOG4108KP7 hydrolase AT706_12590 ENOG41073B9 AT706_12600 ENOG4107AYK membrAne AT706_12605 ENOG4105EPR degv family AT706_12610 ENOG4105D4Y metalloprotease AT706_12615 ENOG410751J AT706_12625 ENOG4105K7K Transcriptional regulator AT706_12645 ENOG4105QNR S1 RNA binding domain protein AT706_12660 ENOG4105MA6 gCN5-related N-acetyltransferase AT706_12665 ENOG4108SZE gCN5-related N-acetyltransferase AT706_12670 ENOG4107RCC Major Facilitator Superfamily AT706_12675 ENOG4105DIA mandelate racemase muconate lactonizing AT706_12685 ENOG41061P3 phosphosulfolactate synthase AT706_12690 ENOG4108N5B 2-phosphosulfolactate phosphatase AT706_12695 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) AT706_12700 ENOG4107RIQ Sulfate adenylate transferase AT706_12705 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) AT706_12710 ENOG4107S9D Alpha beta hydrolase AT706_12715 ENOG4105MYW Pentapeptide repeat protein AT706_12720 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AT706_12725 ENOG4108ZUB Lysine exporter protein (Lyse ygga) AT706_12730 ENOG4105SF0 DinB family AT706_12735 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AT706_12740 ENOG4105ETE Transcriptional regulator (LacI family AT706_12745 ENOG4106HBX Transcriptional Regulator AraC Family AT706_12750 ENOG4105UQX Mate efflux family protein AT706_12760 ENOG4105CAQ asparagine synthetase AT706_12770 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin AT706_12780 ENOG4105ERH Fumarylacetoacetate hydrolase AT706_12835 ENOG4105EYH Exonuclease AT706_12845 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation AT706_12860 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding AT706_12865 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) AT706_12870 ENOG4106K7D Major facilitator family transporter AT706_12875 ENOG4108KK1 membrane protein AbrB duplication AT706_12890 ENOG4105TRI Hydrolase AT706_12905 ENOG4108INS Transcriptional regulator AT706_12910 ENOG4107SCK Monooxygenase AT706_12925 ENOG41060YP AT706_12930 ENOG4106CAD Protein of unknown function (DUF3311) AT706_12935 ENOG4105E1V na solute symporter AT706_12940 ENOG4105X3H Excalibur domain protein AT706_12945 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AT706_12950 ENOG4105XVF Competence transcription factor AT706_12970 ENOG4106YBV Methyl-accepting chemotaxis AT706_12975 ENOG4107ZYJ bioY protein AT706_12980 ENOG4107F3J Amp-dependent synthetase and ligase AT706_12990 ENOG4107TB6 phosphoglycerate mutase AT706_12995 ENOG4108HUF Transporter AT706_13010 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin AT706_13015 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 AT706_13025 ENOG4105CEY Amp-dependent synthetase and ligase AT706_13035 ENOG4105DF9 Lipoate-protein, ligase AT706_13040 ENOG4108RQ5 Beta-lactamase domain-containing protein AT706_13045 ENOG4106AXD AT706_13060 ENOG4105DER m42 family AT706_13070 ENOG41090T1 Membrane AT706_13080 ENOG4105ECB domain protein AT706_13090 ENOG4105C1Q protoporphyrinogen oxidase AT706_13095 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) AT706_13100 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) AT706_13105 ENOG4105BZ4 penicillin-binding protein AT706_13110 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation AT706_13145 ENOG4105K59 histidine triad (HIT) protein AT706_13150 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) AT706_13155 ENOG4105NBU tryptophan transport protein AT706_13190 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) AT706_13200 ENOG4105EQI Metal Dependent Phosphohydrolase AT706_13205 ENOG4106D4I domain protein AT706_13210 ENOG4107VRP DNA repair exonuclease AT706_13215 ENOG4105RHA ABC transporter, permease AT706_13220 ENOG4108IUX (ABC) transporter AT706_13230 ENOG4105CGU Enoyl-CoA hydratase AT706_13240 ENOG4105NCW Trka-c domain protein AT706_13245 ENOG4107S91 Sodium hydrogen exchanger AT706_13250 ENOG4105D4P Coproporphyrinogen iii oxidase AT706_13260 ENOG4105F1N DNA alkylation repair AT706_13265 ENOG4105WZB UPF0342 protein AT706_13270 ENOG4106MP8 UPF0754 membrane protein AT706_13280 ENOG410839P AT706_13300 ENOG4105BZ1 (ABC) transporter AT706_13305 ENOG4105BZ1 (ABC) transporter AT706_13325 ENOG4105F0I Aminotransferase AT706_13330 ENOG4107VMI polysaccharide deacetylase AT706_13335 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) AT706_13340 ENOG4105D64 Mechanosensitive ion channel AT706_13350 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AT706_13355 ENOG4105WMR Protein CrcB homolog AT706_13365 ENOG4105C37 (CBS) domain AT706_13370 ENOG4105CHM Aminotransferase AT706_13380 ENOG4105C37 (CBS) domain AT706_13385 ENOG4105F6E Acyl-transferase AT706_13390 ENOG4108FN7 Aldo keto reductase AT706_13395 ENOG4108AEY RNA polymerase sigma factor AT706_13400 ENOG4105J37 AT706_13420 ENOG4105C8J )-transporter AT706_13425 ENOG4105CUB amino acid AT706_13430 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AT706_13435 ENOG4105BZN citrate synthase AT706_13450 ENOG4105G6Z alkaline phosphatase AT706_13455 ENOG4105ED1 spovr family AT706_13495 ENOG4105WH1 Two component transcriptional regulator luxr family AT706_13500 ENOG4105BZU Histidine kinase AT706_13510 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AT706_13515 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AT706_13525 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator AT706_13530 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) AT706_13535 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase AT706_13540 ENOG4107YBY Hydrolase AT706_13545 ENOG41080XP Cbs domain AT706_13555 ENOG4108YBP pseudouridine synthase AT706_13595 ENOG4105BZU Histidine kinase AT706_13605 ENOG4105VEQ Cold shock protein AT706_13610 ENOG4108TU7 Inherit from COG: (ABC) transporter AT706_13615 ENOG4105CJ1 ABC, transporter AT706_13620 ENOG4105CZV ABC transporter AT706_13625 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family AT706_13640 ENOG4105CS1 NAD(P)H quinone oxidoreductase AT706_13645 ENOG4105C0R drug resistance transporter emrb qaca subfamily AT706_13650 ENOG4105CW7 secretion protein, HlyD family AT706_13655 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes AT706_13665 ENOG4106AKX UPF0229 protein AT706_13670 ENOG4105CYN Serine protein kinase AT706_13690 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AT706_13700 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AT706_13715 ENOG4105VZ8 Transcriptional regulator AT706_13720 ENOG4107D63 AT706_13725 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) AT706_13735 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) AT706_13740 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AT706_13745 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein AT706_13750 ENOG4105E2Y ABC, transporter AT706_13765 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) AT706_13770 ENOG4105EC3 peptidase S51, dipeptidase E AT706_13785 ENOG4108N23 SpoOM-related protein AT706_13900 ENOG4105G5W regulator Fur family AT706_13905 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AT706_13915 ENOG4107NBY Membrane AT706_13920 ENOG4105BZ1 (ABC) transporter AT706_13925 ENOG4105EVI UPF0374 protein AT706_13940 ENOG4105CAN Short-chain dehydrogenase reductase Sdr AT706_13945 ENOG4106BXE AT706_13950 ENOG4105CEN a g-specific adenine glycosylase AT706_13955 ENOG41067AE Membrane-bound metal-dependent hydrolase AT706_13960 ENOG4105EJV Membrane AT706_13965 ENOG4105CKK Glycosyl transferase, family 2 AT706_13970 ENOG4105D74 hydrolase AT706_13975 ENOG4106AKJ AT706_13995 ENOG4105F27 Major Facilitator AT706_14015 ENOG4105ECP epimerase AT706_14030 ENOG4107Y03 Nitroreductase AT706_14035 ENOG4105JAB phenazine biosynthesis protein, phzf family AT706_14040 ENOG4108IHU transport system permease protein AT706_14045 ENOG4105DQ5 transport system permease protein AT706_14050 ENOG4108MES Periplasmic binding protein AT706_14060 ENOG410834F Transcriptional regulator AT706_14065 ENOG4105C0R drug resistance transporter emrb qaca subfamily AT706_14070 ENOG4108YYS metal-dependent hydrolase (By similarity) AT706_14075 ENOG4107Y80 Major Facilitator superfamily AT706_14080 ENOG4105YA8 Transcriptional regulator AT706_14085 ENOG4105H93 Acyltransferase family AT706_14090 ENOG4105CJ1 ABC, transporter AT706_14105 ENOG4105EJ2 Transcriptional regulator AT706_14110 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold AT706_14115 ENOG4105U3E Transcriptional regulator AT706_14125 ENOG4108KYE ABC-2 type transporter AT706_14130 ENOG41090VJ ABC-2 type transporter AT706_14135 ENOG4105CJ1 ABC, transporter AT706_14140 ENOG4105WH1 Two component transcriptional regulator luxr family AT706_14145 ENOG4105BZU Histidine kinase AT706_14150 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase AT706_14160 ENOG4105BZ1 (ABC) transporter AT706_14165 ENOG4105BZ1 (ABC) transporter AT706_14170 ENOG4105CI1 PTS System AT706_14175 ENOG4108Q3X Transcriptional regulator AT706_14180 ENOG4105F8D glycoside hydrolase family 4 AT706_14205 ENOG4105KK4 UPF0060 membrane protein AT706_14210 ENOG41069DP small acid-soluble spore protein AT706_14215 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family AT706_14225 ENOG4107QKR Dehydrogenase AT706_14235 ENOG4107RUY (E1 component), alpha subunit AT706_14260 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AT706_14270 ENOG4105D7N magnesium and cobalt transport protein CorA AT706_14275 ENOG4106KE4 Dehydrogenase AT706_14295 ENOG4105D8X mechanosensitive ion channel AT706_14305 ENOG4105UPD Calcium Proton AT706_14315 ENOG4108ISG Major Facilitator AT706_14325 ENOG4107U9T Pfam:Ribonuclease_BN AT706_14335 ENOG4105KJF protein tyrosine phosphatase AT706_14350 ENOG4107RKG DJ-1/PfpI family AT706_14355 ENOG4105CGH 5'-nucleotidase AT706_14360 ENOG4108RCM Nitroreductase AT706_14365 ENOG4107414 GntR family transcriptional regulator AT706_14370 ENOG4105CG3 alpha amylase, catalytic region AT706_14375 ENOG4105C5Y PTS System AT706_14380 ENOG4105E1K spore germination protein AT706_14385 ENOG4108Q5U germination protein, ger(x)c family AT706_14395 ENOG4105GEU Spore germination protein AT706_14420 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) AT706_14440 ENOG4108RPX mosc domain containing protein AT706_14445 ENOG410855V Acylphosphatase AT706_14475 ENOG4108MRH transcriptional regulatory protein AT706_14485 ENOG4107QPK )-transporter AT706_14490 ENOG4108J20 pectate lyase AT706_14505 ENOG4108HUF Transporter AT706_14510 ENOG4105DQ5 transport system permease protein AT706_14515 ENOG4108U1V ABC transporter, permease AT706_14520 ENOG4105E0A ABC, transporter AT706_14525 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein AT706_14535 ENOG4105FDU atp-dependent rna helicase AT706_14540 ENOG4105C5H ABC transporter AT706_14555 ENOG4105DXB Major Facilitator superfamily AT706_14560 ENOG4107SWG transcriptional regulator MERR family AT706_14570 ENOG4105C5H ABC transporter AT706_14575 ENOG4105FKZ Methyl-accepting chemotaxis AT706_14580 ENOG4105C26 Dehydrogenase AT706_14585 ENOG4105CUB amino acid AT706_14595 ENOG4105EU0 Major facilitator Superfamily AT706_14600 ENOG41090R9 glycosyltransferase AT706_14605 ENOG4107R51 Glycosyl transferase, family 2 AT706_14610 ENOG41090R9 glycosyltransferase AT706_14620 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase AT706_14625 ENOG4105E0M Sulfatase AT706_14630 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) AT706_14635 ENOG4108R1P AT706_14640 ENOG41061H0 Monooxygenase AT706_14645 ENOG4106I4J membrane AT706_14665 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AT706_14670 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) AT706_14675 ENOG4105H67 Protein of unknown function (DUF421) AT706_14680 ENOG4105F8D glycoside hydrolase family 4 AT706_14685 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component AT706_14695 ENOG4105E0S extracellular solute-binding protein family 1 AT706_14700 ENOG4105EKC AT706_14710 ENOG4107TDE lipolytic protein G-D-S-L family AT706_14715 ENOG4105CX8 fg-gap repeat protein AT706_14720 ENOG4105CX8 fg-gap repeat protein AT706_14735 ENOG4107TDE lipolytic protein G-D-S-L family AT706_14740 ENOG41075H3 AraC family transcriptional regulator AT706_14745 ENOG4105F5H Glycosyl Hydrolase Family 88 AT706_14750 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component AT706_14755 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component AT706_14760 ENOG410769Z extracellular solute-binding protein family 1 AT706_14765 ENOG4105EQD regulatoR AT706_14770 ENOG4105C2F Histidine kinase AT706_14785 ENOG4105M18 -acetyltransferase AT706_14790 ENOG4105WEF catalase AT706_14805 ENOG4107S9F NmrA family AT706_14810 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein AT706_14815 ENOG4105M4P Tetr family transcriptional regulator AT706_14825 ENOG4105CDY transcriptional regulatory protein AT706_14845 ENOG4108HFV AT706_14905 ENOG41069I7 AT706_14910 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AT706_14915 ENOG4105CBD Diacylglycerol kinase AT706_14925 ENOG4108IG5 Transcriptional regulator AT706_14930 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AT706_14935 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) AT706_14940 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) AT706_14945 ENOG4105CK7 Sodium proline symporter AT706_14950 ENOG4105KT7 mgtC SapB transporter AT706_14955 ENOG4105CRN Aminoglycoside phosphotransferase AT706_14965 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) AT706_14970 ENOG4105C4R Atp-dependent dna helicase AT706_14975 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) AT706_14985 ENOG4105CBC glutamate synthase AT706_14990 ENOG4105KGF protein, YerC YecD AT706_14995 ENOG4108R5T secreted protein AT706_15010 ENOG4105DVH amino acid AT706_15020 ENOG4105C12 Phosphoribosylglycinamide synthetase AT706_15025 ENOG4105DC1 bifunctional purine biosynthesis protein purh AT706_15030 ENOG4108V3E phosphoribosylglycinamide formyltransferase AT706_15035 ENOG4105CXB phosphoribosylaminoimidazole synthetase AT706_15045 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii AT706_15050 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I AT706_15055 ENOG4105VR9 phosphoribosylformylglycinamidine synthase AT706_15060 ENOG4105C8V SAICAR synthetase AT706_15065 ENOG4105C83 adenylosuccinate lyase AT706_15070 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AT706_15075 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AT706_15100 ENOG4105C7N Xanthine uracil vitamin C permease AT706_15130 ENOG4105C7R Atpase associated with various cellular activities aaa_3 AT706_15145 ENOG4105C85 amino acid AT706_15150 ENOG4107STQ Multicopper oxidase AT706_15160 ENOG4107YUH hydrolase AT706_15190 ENOG4107QNK )-transporter AT706_15195 ENOG4108ZMR Ion transport 2 domain-containing protein AT706_15205 ENOG4108WV1 Pfam:DUF477 AT706_15210 ENOG4105DQX Zinc finger domain AT706_15215 ENOG41087YS Phage shock protein A AT706_15225 ENOG4105CT4 transporter AT706_15230 ENOG4105CPQ Dehydrogenase AT706_15235 ENOG4105PGZ NB-ARC domain AT706_15245 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) AT706_15250 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) AT706_15255 ENOG4108TYN CAAX amino terminal protease family protein AT706_15265 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AT706_15270 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AT706_15275 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) AT706_15280 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AT706_15285 ENOG4105C5H ABC transporter AT706_15290 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) AT706_15295 ENOG410801F ribosomal-protein-alanine acetyltransferase AT706_15300 ENOG41072GX Peptidase M22 Glycoprotease AT706_15305 ENOG4105K8N protein family UPF0079, ATPase AT706_15310 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AT706_15355 ENOG4105D3P Mannan endo-1,4-beta-mannosidase AT706_15360 ENOG4105DG6 mannose-6-phosphate isomerase AT706_15365 ENOG4105EVU fructokinase AT706_15370 ENOG4108TZY GntR Family Transcriptional Regulator AT706_15375 ENOG4105CS2 ec 3.2.1.21 AT706_15380 ENOG4105CK1 PTS System AT706_15385 ENOG4105VCP PTS System AT706_15390 ENOG4105VZJ PTS System AT706_15395 ENOG4105F27 Major Facilitator AT706_15400 ENOG41090UD (LipO)protein AT706_15405 ENOG4107TVP HD domain protein AT706_15410 ENOG4108YM7 Gcn5-related n-acetyltransferase AT706_15420 ENOG4108ZMX Domain of unknown function (DU1801) AT706_15425 ENOG4105G6Z alkaline phosphatase AT706_15440 ENOG4105VRS hydrolase family 18 AT706_15445 ENOG4105DRR Transcriptional regulator, GntR family AT706_15455 ENOG4105C2C drug resistance transporter, Bcr CflA AT706_15460 ENOG4105FS7 Transcriptional regulator AT706_15465 ENOG4108TVJ Nitroreductase AT706_15470 ENOG4105EYF MMPL domain protein AT706_15475 ENOG41062A4 Transcriptional regulator AT706_15485 ENOG4105C85 amino acid AT706_15500 ENOG4105F27 Major Facilitator AT706_15510 ENOG4105WQG acetyltransferase AT706_15520 ENOG4105PF9 Transcriptional regulator AT706_15545 ENOG410900G Protein of unknown function (DUF421) AT706_15565 ENOG4105XXY Thioredoxin AT706_15570 ENOG4108VGI doxx family AT706_15575 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase AT706_15580 ENOG4108TVJ Nitroreductase AT706_15585 ENOG41076HS cation diffusion facilitator family transporter AT706_15590 ENOG4108Z5V transcriptional regulator, merr family AT706_15595 ENOG4108UQV Membrane AT706_15600 ENOG4108WC5 Alpha Beta Hydrolase Fold protein AT706_15605 ENOG4105EYF MMPL domain protein AT706_15610 ENOG4108VB1 regulatoR AT706_15615 ENOG4105ENE Histidine kinase AT706_15625 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) AT706_15630 ENOG4108ZHR arsR family transcriptional regulator AT706_15635 ENOG4108SQ9 flavin reductase domain protein, FMN-binding AT706_15645 ENOG4107Y9U Membrane AT706_15650 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AT706_15655 ENOG4105US7 Histidine kinase AT706_15665 ENOG4108ZJ4 polysaccharide deacetylase AT706_15670 ENOG4108KGH TRANSCRIPTIONal AT706_15675 ENOG4105Z7P Acetyltransferase (GNAT) family AT706_15685 ENOG4107R5R arsenical pump membrane protein AT706_15690 ENOG41082YX Transcriptional regulator, arsr family AT706_15700 ENOG4108JGH Tetr family transcriptional regulator AT706_15705 ENOG4105EQ0 Major Facilitator superfamily AT706_15710 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein AT706_15715 ENOG4105KVH Transcriptional regulator AT706_15725 ENOG4107Z6X Transcriptional regulator AT706_15730 ENOG4105MJ9 esterase AT706_15735 ENOG4108ZMQ domain protein AT706_15740 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family AT706_15745 ENOG4105T38 integral membrane protein AT706_15750 ENOG4105GIG AT706_15755 ENOG4105CZ9 Domain of unknown function (DU1801) AT706_15765 ENOG4105DXI Major Facilitator superfamily AT706_15770 ENOG4107U9B transcriptional regulator AT706_15775 ENOG41086D8 Transcriptional regulator AT706_15780 ENOG4108UZ3 Transporter AT706_15785 ENOG4108MCI Transcriptional regulator, ARAC family AT706_15790 ENOG4108VJ1 Transcriptional regulator (CarD family AT706_15795 ENOG4105VEQ Cold shock protein AT706_15800 ENOG4105ECK Fatty Acid Desaturase AT706_15810 ENOG4105VZ8 Transcriptional regulator AT706_15825 ENOG4105BZ1 (ABC) transporter AT706_15830 ENOG4105CJA serine threonine protein kinase AT706_15835 ENOG4105CJA serine threonine protein kinase AT706_15895 ENOG4105RV9 Transcriptional regulator AT706_15900 ENOG4105M5P UPF0310 protein AT706_15915 ENOG41064BQ Phosphatase AT706_15925 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) AT706_15930 ENOG4105WN5 stage II sporulation protein AT706_15935 ENOG4107SGM protein serine threonine phosphatase AT706_15940 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase AT706_15945 ENOG4105FUA antagonist AT706_15950 ENOG4107MMM Anti-sigma-factor antagonist AT706_15955 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) AT706_15965 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AT706_15970 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein AT706_15975 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) AT706_15985 ENOG4105CKV Membrane AT706_15990 ENOG410905X membrane-flanked domain protein AT706_15995 ENOG4105C1J atp-dependent rna helicase AT706_16000 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) AT706_16005 ENOG4105CPF Cell wall formation (By similarity) AT706_16010 ENOG4105SZ6 Thioredoxin AT706_16030 ENOG4105FDT acyl-CoA dehydrogenase AT706_16045 ENOG4105CJ1 ABC, transporter AT706_16055 ENOG4106F5Q Membrane AT706_16060 ENOG4107QJT sodium dicarboxylate symporter AT706_16065 ENOG4108MRH transcriptional regulatory protein AT706_16070 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism AT706_16075 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AT706_16090 ENOG41082W1 Cupin 2, conserved barrel domain protein AT706_16095 ENOG4105QVS general stress protein AT706_16100 ENOG4105EU9 AT706_16105 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) AT706_16115 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) AT706_16140 ENOG4105C0X amino acid AT706_16150 ENOG4107R8N Glycosyl transferase, family 2 AT706_16155 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) AT706_16170 ENOG4105C9U ATP-dependent DNA helicase RecQ AT706_16180 ENOG4105VCH membrane AT706_16190 ENOG410606W general stress protein AT706_16205 ENOG4105CYX Short-chain dehydrogenase reductase Sdr AT706_16210 ENOG4105HMZ Methyltransferase AT706_16220 ENOG4105ETD TRANSCRIPTIONal AT706_16225 ENOG4107QM2 Aldo Keto reductase AT706_16230 ENOG4107RVG penicillin-binding protein AT706_16235 ENOG41061CK Antibiotic biosynthesis monooxygenase AT706_16245 ENOG4105XJB lipolytic protein G-D-S-L family AT706_16250 ENOG4107258 Transcriptional regulator AT706_16260 ENOG4105P4J Allophanate hydrolase, subunit 1 AT706_16265 ENOG4105CFM UPF0317 protein AT706_16270 ENOG4105C5A transporter AT706_16275 ENOG4105E7W lamb ycsf family protein AT706_16300 ENOG4108ZX0 Signal peptidase I AT706_16305 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AT706_16330 ENOG4108ZYE Transcriptional regulator AT706_16335 ENOG4108T5E Copper resistance protein AT706_16340 ENOG4105KTB nuclear export factor GLE1 AT706_16345 ENOG4105H9W Short-chain dehydrogenase reductase Sdr AT706_16355 ENOG4105C26 Dehydrogenase AT706_16360 ENOG4108JPW Aminotransferase AT706_16370 ENOG4105YVS arsR family transcriptional regulator AT706_16375 ENOG41067V3 Antibiotic biosynthesis monooxygenase AT706_16380 ENOG4108DBC nitroreductase AT706_16385 ENOG4105R8C Transcriptional regulator AT706_16400 ENOG4108IPW abc transporter atp-binding protein AT706_16405 ENOG4105CM4 permease protein AT706_16410 ENOG4105DHS permease protein AT706_16415 ENOG4105CFH Aspartokinase AT706_16435 ENOG4105BZU Histidine kinase AT706_16440 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AT706_16445 ENOG4107WD8 ABC transporter, permease AT706_16465 ENOG4105E1K spore germination protein AT706_16480 ENOG4105DUX Transporter AT706_16490 ENOG41069ZX AT706_16495 ENOG41069ZX AT706_16500 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AT706_16505 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AT706_16510 ENOG4106P55 Transcriptional regulator AT706_16520 ENOG4105DRP amino acid AbC transporter AT706_16525 ENOG4105CDA abc transporter atp-binding protein AT706_16535 ENOG4105W8Z 4'-phosphopantetheinyl transferase AT706_16545 ENOG4105SX7 Transporter AT706_16575 ENOG4105CEY Amp-dependent synthetase and ligase AT706_16585 ENOG4105KVH Transcriptional regulator AT706_16590 ENOG4108VA3 3-hexulose-6-phosphate synthase AT706_16595 ENOG41080HJ 6-phospho 3-hexuloisomerase AT706_16600 ENOG4105C8Q Methyl-accepting chemotaxis AT706_16615 ENOG4105CS2 ec 3.2.1.21 AT706_16625 ENOG4105HHM rdd domain containing protein AT706_16635 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein AT706_16640 ENOG4105E5Q amino acid AbC transporter AT706_16645 ENOG4105CKI cobalamin synthesis protein AT706_16655 ENOG4105S7A ErfK ybiS ycfS ynhG family protein AT706_16675 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AT706_16680 ENOG4108IFG nitrite reductase, (NAD(P)H) AT706_16685 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit AT706_16690 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) AT706_16700 ENOG4105U6C Alpha beta hydrolase fold protein AT706_16705 ENOG4108PJD permease AT706_16715 ENOG4107YHD transcriptional regulator AT706_16720 ENOG4105CK7 Sodium proline symporter AT706_16725 ENOG4105C26 Dehydrogenase AT706_16735 ENOG410756H nucleotidyltransferase AT706_16740 ENOG4105I82 acetyl xylan esterase AT706_16745 ENOG4105C5Q Transcriptional regulator AT706_16750 ENOG41089UC methyltransferase, type 11 AT706_16755 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) AT706_16760 ENOG4105I1F Resistance protein AT706_16765 ENOG4107RA1 nh(3)-dependent nad( ) synthetase AT706_16770 ENOG4105EIG urea carboxylase-associated protein 1 AT706_16805 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) AT706_16840 ENOG4107SQ8 Glycine betaine AT706_16845 ENOG4108IJ7 Glycine betaine AT706_16850 ENOG4108A65 Transcriptional regulator AT706_16855 ENOG4107XZQ multidrug resistance protein AT706_16860 ENOG41079KZ Major Facilitator Superfamily AT706_16870 ENOG4108TTB tellurium resistance protein AT706_16875 ENOG4107TS3 membrane protein, TerC AT706_16880 ENOG4106FN3 tellurium resistance protein AT706_16885 ENOG4106FN3 tellurium resistance protein AT706_16890 ENOG4108N0M stress protein AT706_16895 ENOG4105DEN Luciferase family AT706_16905 ENOG4105DIK (ABC) transporter AT706_16910 ENOG4105DSE periplasmic solute binding protein AT706_16920 ENOG4105H9W Short-chain dehydrogenase reductase Sdr AT706_16950 ENOG4107SET aldo keto reductase AT706_16955 ENOG4108SDH ABC, transporter AT706_16960 ENOG4108IUW ABC transporter AT706_16965 ENOG4107Y7X LytTR AT706_16975 ENOG41060AI SEC-C motif AT706_16985 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold AT706_16990 ENOG4107RB3 L-asparaginase AT706_16995 ENOG4105J7D transcriptional regulator AT706_17000 ENOG4105C0R drug resistance transporter emrb qaca subfamily AT706_17005 ENOG4107EPV Aminotransferase class V AT706_17010 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) AT706_17015 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AT706_17020 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AT706_17025 ENOG4105DGI Alkaline phosphatase AT706_17035 ENOG4105MUA Resistance protein AT706_17070 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AT706_17075 ENOG4106UX7 integral membrane protein AT706_17090 ENOG4105CTX dehydratase AT706_17095 ENOG41073TP transcriptional regulator AT706_17100 ENOG4105EQX glucarate dehydratase AT706_17105 ENOG4105DJB Major Facilitator Superfamily AT706_17110 ENOG4105C26 Dehydrogenase AT706_17115 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase AT706_17130 ENOG4105CSV Glutaminase AT706_17145 ENOG4108J5H Homocysteine s-methyltransferase AT706_17150 ENOG4108IQI permease AT706_17155 ENOG4105CM2 brancheD-chain amino acid aminotransferase AT706_17165 ENOG4108X79 transcriptional regulator AT706_17170 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) AT706_17175 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane AT706_17185 ENOG4105C72 UPF0176 protein AT706_17205 ENOG4107ZTW SNARE associated Golgi AT706_17210 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase AT706_17215 ENOG4108WC5 Alpha Beta Hydrolase Fold protein AT706_17225 ENOG4108TCS Glutamyl endopeptidase AT706_17230 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR AT706_17235 ENOG4106BHF AT706_17240 ENOG41065RQ ADP-ribosylation crystallin J1 AT706_17245 ENOG4106AXJ AraC family transcriptional regulator AT706_17250 ENOG410631K Membrane AT706_17260 ENOG4105DCM major facilitator superfamily AT706_17265 ENOG410645S MarR family Transcriptional regulator AT706_17275 ENOG4105CXY transporter AT706_17280 ENOG4107VXM glycerophosphoryl diester phosphodiesterase AT706_17285 ENOG4107QTZ amino acid AT706_17295 ENOG4107E6A Cytochrome p-450 AT706_17300 ENOG4108HWY Beta-lactamase AT706_17310 ENOG4106DDH Sporulation-specific SASP protein AT706_17320 ENOG4106K80 AT706_17330 ENOG4105G0J serine threonine protein kinase AT706_17365 ENOG4108RWP Major Facilitator Superfamily protein AT706_17370 ENOG4105WAB arsR family transcriptional regulator AT706_17380 ENOG4105GPN Uncharacterized conserved protein (DUF2294) AT706_17400 ENOG4108TWJ NADH dehydrogenase subunit 5 AT706_17410 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) AT706_17415 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) AT706_17420 ENOG4107U5W ybbr family AT706_17425 ENOG4105C8B TIGR00159 family AT706_17435 ENOG4105EMN RNA polymerase sigma factor AT706_17465 ENOG4105EWC Purine nucleoside phosphorylase AT706_17475 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate AT706_17495 ENOG4105D17 glycoside hydrolase, family 3 domain protein AT706_17500 ENOG4105EHZ conserved protein UCP016719 AT706_17505 ENOG410874W AraC family transcriptional regulator AT706_17525 ENOG4108SA1 esterase AT706_17535 ENOG4105CHH sulfate transporter AT706_17620 ENOG4108NMV polysaccharide deacetylase AT706_17635 ENOG4105D1F ATP-binding protein AT706_17650 ENOG4108I0C methyltransferase AT706_17655 ENOG4108UJD 30S ribosomal protein S9 AT706_17660 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) AT706_17665 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) AT706_17670 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) AT706_17675 ENOG4108JJB ABC transporter AT706_17680 ENOG4108JJB ABC transporter AT706_17685 ENOG4108ZT0 50S ribosomal protein l17 AT706_17690 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AT706_17695 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) AT706_17700 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits AT706_17710 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) AT706_17720 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AT706_17730 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AT706_17735 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) AT706_17740 ENOG4105VPB 50S ribosomal protein L30 AT706_17745 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) AT706_17750 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) AT706_17755 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) AT706_17760 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) AT706_17770 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits AT706_17780 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) AT706_17785 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal AT706_17790 ENOG41082SA 50s ribosomal protein l29 AT706_17795 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) AT706_17800 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) AT706_17805 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) AT706_17810 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) AT706_17815 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity AT706_17820 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) AT706_17825 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) AT706_17830 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) AT706_17835 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) AT706_17840 ENOG4107SKW Inherit from COG: Alpha beta hydrolase AT706_17845 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) AT706_17850 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) AT706_17855 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) AT706_17860 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) AT706_17865 ENOG4105XPM ribosomal protein AT706_17870 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AT706_17875 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) AT706_17880 ENOG4107Y49 methyltransferase AT706_17885 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) AT706_17890 ENOG4108VZM 50s ribosomal protein L10 AT706_17900 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) AT706_17905 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AT706_17925 ENOG4105M0M Tetracycline resistance protein AT706_17930 ENOG4105C2N RNA methyltransferase TrmH family group 3 AT706_17935 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) AT706_17940 ENOG4105C8N cysteinyl-tRNA synthetase AT706_17945 ENOG4105D7W serine acetyltransferase AT706_17955 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) AT706_17960 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) AT706_17965 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) AT706_17970 ENOG4105CTP PilT protein domain protein AT706_17975 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) AT706_17980 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AT706_17990 ENOG41066A3 ATP guanido phosphotransferase AT706_17995 ENOG4108Z0C Uvrb UvrC protein AT706_18085 ENOG4105CRK lysyL-tRNA synthetase AT706_18090 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AT706_18100 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AT706_18105 ENOG4105KRF dihydroneopterin aldolase AT706_18110 ENOG4105EEI dihydropteroate synthase AT706_18115 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 AT706_18120 ENOG4105DDQ anthranilate synthase AT706_18125 ENOG4105CRQ synthase (Component I) AT706_18130 ENOG4105C6T cysteine synthase AT706_18135 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase AT706_18140 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) AT706_18150 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AT706_18155 ENOG4108UGV hypoxanthine phosphoribosyltransferase AT706_18160 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AT706_18190 ENOG41060GV RNA binding s1 domain protein AT706_18205 ENOG4105VYY sporulation protein yabp AT706_18210 ENOG41082I2 s4 domain protein AT706_18215 ENOG4108IY2 MazG family AT706_18225 ENOG4108M14 stage v sporulation protein t AT706_18230 ENOG4108JA2 transcriptioN-repair coupling factor AT706_18240 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) AT706_18245 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) AT706_18250 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AT706_18255 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) AT706_18265 ENOG4105K4W Could be involved in septation (By similarity) AT706_18270 ENOG4105KME endoribonuclease L-psp AT706_18275 ENOG4105DFT pur operon repressor AT706_18280 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) AT706_18285 ENOG4105XEW small acid-soluble spore protein AT706_18290 ENOG4105W42 Veg protein AT706_18295 ENOG4105XFA sporulation peptidase YabG AT706_18300 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) AT706_18310 ENOG41069ER domain protein AT706_18315 ENOG4105F8V Hydrolase, tatD family AT706_18320 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) AT706_18325 ENOG4105KRN Transcriptional regulator, abrb family AT706_18330 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AT706_18335 ENOG4105VC4 domain protein AT706_18340 ENOG41060K3 Methyltransferase AT706_18345 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) AT706_18350 ENOG4105MA4 psp1 domain protein AT706_18355 ENOG4105FA2 dna polymerase iii AT706_18360 ENOG4105XVJ Protein of unknown function (DUF327) AT706_18365 ENOG4105X0R protein from nitrogen regulatory protein P-II AT706_18370 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) AT706_18375 ENOG4105CXN decarboxylase AT706_18380 ENOG4105CDW Resistance protein AT706_18420 ENOG41067KS pro-sigma K processing AT706_18430 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) AT706_18435 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) AT706_18440 ENOG4105C6E dna polymerase iii AT706_18445 ENOG4108Z6B deaminase AT706_18450 ENOG4105GTG Isochorismatase AT706_18455 ENOG4105VRS hydrolase family 18 AT706_18465 ENOG4105ZMH deoxynucleoside kinase AT706_18475 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) AT706_18480 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) AT706_18485 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) AT706_18495 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AT706_18530 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AT706_18535 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AT706_18550 ENOG410848D S4 domain protein YaaA AT706_18555 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AT706_18560 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) AT706_18570 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) AT706_18585 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) AT706_18590 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) AT706_18595 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) AT706_18610 ENOG4107QJE Chromosome Partitioning Protein AT706_18615 ENOG4105FA0 parb-like partition protein AT706_18620 ENOG4108ZDA Sporulation protein YyaC AT706_18630 ENOG4105VDK protein, conserved in bacteria AT706_18635 ENOG4108J2R molybdopterin oxidoreductase AT706_18640 ENOG4105C3G gtp-binding protein AT706_18645 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) AT706_18650 ENOG4108UUM single-stranded DNA-binding protein AT706_18655 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) AT706_18660 ENOG4105CGK Exodeoxyribonuclease III AT706_18670 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase AT706_18675 ENOG4108UW5 maltose o-acetyltransferase AT706_18685 ENOG4107FCW Abortive infection protein AT706_18690 ENOG4105C7Z Conserved Protein AT706_18700 ENOG4107YVC modification (methylase) AT706_18705 ENOG4105C7Z Conserved Protein AT706_18710 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AT706_18720 ENOG41085FC arsR family transcriptional regulator AT706_18725 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase AT706_18730 ENOG4105D6J arsenicaL-resistance protein AT706_18735 ENOG4108UXE Protein tyrosine phosphatase AT706_18740 ENOG4105C7Z Conserved Protein AT706_18745 ENOG4105NAE bifunctional deaminase-reductase domain protein AT706_18750 ENOG4105UNS Pfam:DUF419 AT706_18755 ENOG4108U7W acetyltransferase AT706_18765 ENOG41082BV acetyltransferase AT706_18770 ENOG4108U05 Transcriptional regulator AT706_18785 ENOG4108VP3 Lysine exporter protein (LysE YggA) AT706_18790 ENOG4107V2S Transcriptional regulator AT706_18795 ENOG41081I9 integral membrane protein AT706_18800 ENOG41082BV acetyltransferase AT706_18805 ENOG4107RSM transcriptional regulator AT706_18810 ENOG4105D94 Major Facilitator Superfamily AT706_18815 ENOG4105DDN Pentapeptide repeat-containing protein AT706_18820 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein AT706_18830 ENOG41090E6 transcriptional regulator MERR family AT706_18850 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase AT706_18855 ENOG4105KVH Transcriptional regulator AT706_18870 ENOG4108XMW Membrane AT706_18875 ENOG4105BZR domain protein AT706_18880 ENOG4105K9Q Binds to the 23S rRNA (By similarity) AT706_18885 ENOG4105EDW glycosyl transferase, family 39 AT706_18890 ENOG4105DJ2 Major Facilitator Superfamily AT706_18915 ENOG4105CDU Replicative dna helicase AT706_18920 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase AT706_18925 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis AT706_18950 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AT706_18955 ENOG4105BZU Histidine kinase AT706_18970 ENOG4105Q2H domain protein AT706_18975 ENOG4105C0H protease AT706_18985 ENOG4105BZU Histidine kinase AT706_18990 ENOG4108JUB Transcriptional regulator AT706_18995 ENOG4105C8Y Acetylornithine aminotransferase AT706_19000 ENOG4108IQI permease AT706_19005 ENOG41066UZ arginase EC 3.5.3.1 AT706_19015 ENOG410780I phosphoprotein phosphatase activity AT706_19020 ENOG4105WQG acetyltransferase AT706_19025 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) AT706_19045 ENOG4105E2A Dehydrogenase AT706_19060 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) AT706_19075 ENOG4107QMH DNA methylase AT706_19085 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 AT706_19090 ENOG4108Z15 abc transporter atp-binding protein AT706_19095 ENOG4106KKU AT706_19105 ENOG4108S3Y transcriptional regulator AT706_19115 ENOG4105CS2 ec 3.2.1.21 AT706_19125 ENOG4108JU3 Alkyl hydroperoxide reductase AT706_19130 ENOG4105D3R alkyl hydroperoxide reductase AT706_19135 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AT706_19140 ENOG4105C6Z Gluconate AT706_19145 ENOG4105CMG Carbohydrate kinase AT706_19150 ENOG4105G3Z GntR family transcriptional regulator AT706_19155 ENOG4105BZW Glycerate kinase AT706_19165 ENOG41067MG lrgb family AT706_19175 ENOG41061AU MarR family Transcriptional regulator AT706_19180 ENOG4107JEE Short-chain dehydrogenase reductase Sdr AT706_19185 ENOG4105J7D transcriptional regulator AT706_19200 ENOG41085PJ rdd domain containing protein AT706_19210 ENOG4108ITS PQQ enzyme repeat AT706_19215 ENOG41085PJ rdd domain containing protein AT706_19220 ENOG4105C26 Dehydrogenase AT706_19225 ENOG4105ST3 Transcriptional regulator AT706_19230 ENOG41061TZ Short-chain dehydrogenase reductase Sdr AT706_19240 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) AT706_19245 ENOG4107QNK )-transporter AT706_19260 ENOG4105CPC Aldo Keto reductase AT706_19270 ENOG4105C26 Dehydrogenase AT706_19280 ENOG4105D7K pfkb domain protein AT706_19285 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) AT706_19290 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) AT706_19300 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AT706_19305 ENOG4105F0H myo-inositol catabolism protein AT706_19310 ENOG4107TRN Xylose isomerase domain protein TIM barrel AT706_19315 ENOG4105D2N Aldolase AT706_19345 ENOG4108V5C ABC transporter AT706_19375 ENOG410667J hydrolase AT706_19380 ENOG4107QHE Choloylglycine hydrolase AT706_19385 ENOG4105CPU Monooxygenase AT706_19390 ENOG4108XSB acetyltransferase, (GNAT) family AT706_19395 ENOG4105EAB amino acid AbC transporter AT706_19400 ENOG4108HW4 amino acid AbC transporter AT706_19410 ENOG4105CH2 amidohydrolase AT706_19415 ENOG4108PGP mmge prpd family protein AT706_19420 ENOG4105ENY Ethanolamine utilization protein eutH AT706_19425 ENOG4108TM9 integral membrane protein AT706_19430 ENOG4107RHR regulatoR AT706_19440 ENOG4105D9N nucleoside AT706_19445 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) AT706_19455 ENOG4107W25 arginase agmatinase formiminoglutamase AT706_19460 ENOG4105CI2 imidazolone-5-propionate hydrolase AT706_19465 ENOG4105CGP Urocanate hydratase AT706_19470 ENOG4105C84 Histidine ammonia-lyase AT706_19480 ENOG4106Z5D Glycoside Hydrolase Family 43 AT706_19485 ENOG4105M6F mutator MutT protein AT706_19495 ENOG4108F3G Type I restriction-modification system, R subunit AT706_19510 ENOG4107EV6 Inherit from COG: YD repeat protein AT706_19560 ENOG4105C5Y PTS System AT706_19565 ENOG4105CS2 ec 3.2.1.21 AT706_19570 ENOG4107YZX Universal stress protein AT706_19595 ENOG4107TDE lipolytic protein G-D-S-L family AT706_19600 ENOG4105C1J atp-dependent rna helicase AT706_19605 ENOG4105DEU major facilitator superfamily AT706_19615 ENOG4105CID antiterminator AT706_19620 ENOG4108RZ2 Glycoside hydrolase family 16 AT706_19625 ENOG4105D4T Citrate transporter AT706_19630 ENOG4105CH6 catalase AT706_19650 ENOG4105DHI Methyltransferase AT706_19660 ENOG4105CY2 Citrate transporter AT706_19665 ENOG4105D6N CoA-transferase, subunit a AT706_19670 ENOG4108IIH CoA-transferase subunit B AT706_19675 ENOG4105DTD Dehydrogenase AT706_19705 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AT706_19710 ENOG4105WH1 Two component transcriptional regulator luxr family AT706_19715 ENOG4105BZU Histidine kinase AT706_19725 ENOG4108WAV Transcriptional regulator AT706_19730 ENOG4105KIS phospholipid-binding protein AT706_19735 ENOG4105CMR udp-glucose 4-epimerase AT706_19745 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) AT706_19765 ENOG4107BJW polysaccharide deacetylase AT706_19780 ENOG4105D2K citrate carrier protein AT706_19785 ENOG4105C4M (Ubiquinol oxidase) subunit I AT706_19790 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AT706_19795 ENOG4108JJ9 ABC, transporter AT706_19800 ENOG4108JJ8 (ABC) transporter AT706_19805 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AT706_19810 ENOG4105ETS cytosine purines uracil thiamine allantoin AT706_19830 ENOG41069JR AT706_19835 ENOG4105DA5 (ABC) transporter AT706_19850 ENOG4105CH6 catalase AT706_19855 ENOG4108VX5 3-methyladenine DNA glycosylase AT706_19865 ENOG4105EMD TRANSCRIPTIONal AT706_19870 ENOG4105VZJ PTS System AT706_19875 ENOG4105CK1 PTS System AT706_19880 ENOG4105VCP PTS System AT706_19885 ENOG4105F8D glycoside hydrolase family 4 AT706_19890 ENOG4105CM2 brancheD-chain amino acid aminotransferase AT706_19895 ENOG4108VHC Short-chain dehydrogenase reductase Sdr AT706_19900 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD AT706_19910 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein AT706_19915 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) AT706_19930 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AT706_19940 ENOG4105IIU Aminopeptidase AT706_19945 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) AT706_19950 ENOG4105GVJ transcriptional regulator AT706_19960 ENOG4105X1N Glycosyl transferase family 8 AT706_19975 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin AT706_19985 ENOG4105CK1 PTS System AT706_20000 ENOG4105DR4 Methyltransferase AT706_20010 ENOG4105D8G Major Facilitator superfamily AT706_20015 ENOG41067MG lrgb family AT706_20020 ENOG4105VAW lrga family AT706_20025 ENOG4105CMU LysR family (Transcriptional regulator AT706_20035 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) AT706_20040 ENOG4107SJW iron permease, FTR1 AT706_20045 ENOG410650H (LipO)protein AT706_20050 ENOG4105DBE peroxidase AT706_20055 ENOG4107ZXU DSBA oxidoreductase AT706_20080 ENOG4105WH5 Teichoic acid glycosylation protein AT706_20085 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) AT706_20095 ENOG4107BMA Transglycosylase associated protein AT706_20100 ENOG4105E2S oxidase) subunit II AT706_20105 ENOG4105BZ9 Cytochrome C oxidase, subunit I AT706_20110 ENOG4105CCU oxidase (Subunit III) AT706_20115 ENOG41060D1 Quinol oxidase AT706_20130 ENOG4108DBC nitroreductase AT706_20135 ENOG4105DEN Luciferase family AT706_20140 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin AT706_20160 ENOG4105C5Y PTS System AT706_20175 ENOG4105DWF phosphomethylpyrimidine kinase AT706_20180 ENOG4108RJ9 Glycosyl transferase, family 2 AT706_20185 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) AT706_20190 ENOG4105C26 Dehydrogenase AT706_20230 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AT706_20235 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD AT706_20245 ENOG4107TY6 Acylneuraminate cytidylyltransferase AT706_20250 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG AT706_20255 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AT706_20260 ENOG4105C1B dTDP-glucose 4-6-dehydratase AT706_20265 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase AT706_20270 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase AT706_20280 ENOG4105D82 Glutamate dehydrogenase AT706_20285 ENOG4105C26 Dehydrogenase AT706_20300 ENOG4105FCW Major Facilitator superfamily AT706_20305 ENOG41061WN bacilysin biosynthesis protein AT706_20310 ENOG4106CHD Bacilysin biosynthesis protein bacB AT706_20315 ENOG4105CHR reductase AT706_20320 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase AT706_20330 ENOG4105CHM Aminotransferase AT706_20345 ENOG4108IJ2 phosphate acetyltransferase AT706_20350 ENOG4105DUM transcriptional regulator, lysR family AT706_20355 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) AT706_20360 ENOG4108RNG Permease of the drug metabolite transporter AT706_20365 ENOG4108VCI transcription factor, rsfa family AT706_20375 ENOG4105DCI Phosphohydrolase AT706_20385 ENOG41062ES Transcriptional regulator AT706_20390 ENOG4105C57 major facilitator superfamily AT706_20400 ENOG4105C22 threonyL-tRNA synthetase AT706_20405 ENOG41067TZ transcriptional regulator, MarR family AT706_20410 ENOG41069HH 4-oxalocrotonate tautomerase AT706_20415 ENOG4108Z4T Peptidase M50 AT706_20420 ENOG4108XFG YwhD family AT706_20425 ENOG4105BZ4 penicillin-binding protein AT706_20430 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) AT706_20435 ENOG4105CYW agmatinase AT706_20445 ENOG4108RDQ ABC transporter AT706_20475 ENOG4107JM4 Tetratricopeptide repeat AT706_20525 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E AT706_20535 ENOG410684U Domain of unknown function (DUF1934) AT706_20540 ENOG4105C75 arginyL-tRNA synthetase AT706_20550 ENOG4107V6Q Cyclic nucleotide-binding domain AT706_20570 ENOG4108IUE nitrate reductase beta subunit AT706_20575 ENOG4105R3A Nitrate reductase AT706_20590 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) AT706_20595 ENOG4105BZ1 (ABC) transporter AT706_20600 ENOG4105NAE bifunctional deaminase-reductase domain protein AT706_20610 ENOG4105E5J UV damage endonuclease AT706_20620 ENOG4105DF6 Fe-S oxidoreductase AT706_20625 ENOG4105C1G acyl-Coa dehydrogenase AT706_20635 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) AT706_20645 ENOG410812K response regulator receiver protein AT706_20650 ENOG4105D2N Aldolase AT706_20655 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway AT706_20665 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)