locus-tag	class	description
IMZ18_00005	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IMZ18_00010	COG1481	regulation of sporulation
IMZ18_00015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_00020	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IMZ18_00030	COG0745	RESPONSE REGULATOR receiver
IMZ18_00035	COG5002	protein histidine kinase activity
IMZ18_00040	COG1136	(ABC) transporter
IMZ18_00045	COG0577	efflux transmembrane transporter activity
IMZ18_00050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMZ18_00055	COG0288	reversible hydration of carbon dioxide
IMZ18_00060	COG0659	secondary active sulfate transmembrane transporter activity
IMZ18_00070	COG1611	Belongs to the LOG family
IMZ18_00075	COG1609	Transcriptional regulator
IMZ18_00085	COG2182	Extracellular solute-binding protein
IMZ18_00090	COG1175	transmembrane transport
IMZ18_00095	COG3833	ABC-type maltose transport systems, permease component
IMZ18_00100	COG5521	maltodextrose utilization protein MalA
IMZ18_00105	COG1554	hydrolase, family 65, central catalytic
IMZ18_00110	COG0366	Alpha amylase catalytic
IMZ18_00115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMZ18_00120	COG0740	serine-type endopeptidase activity
IMZ18_00130	COG4974	Belongs to the 'phage' integrase family
IMZ18_00240	COG0582	viral genome integration into host DNA
IMZ18_00320	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMZ18_00355	COG5632	N-Acetylmuramoyl-L-alanine amidase
IMZ18_00355	COG1388	LysM domain
IMZ18_00355	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_00375	COG1674	ftsk spoiiie
IMZ18_00395	COG2076	Multidrug Resistance protein
IMZ18_00400	COG2076	Multidrug Resistance protein
IMZ18_00405	COG1309	transcriptional regulator
IMZ18_00410	COG0531	amino acid
IMZ18_00415	COG1621	beta-fructofuranosidase activity
IMZ18_00420	COG1621	beta-fructofuranosidase activity
IMZ18_00430	COG1794	racemase activity, acting on amino acids and derivatives
IMZ18_00445	COG3479	Phenolic acid decarboxylase
IMZ18_00455	COG2272	Belongs to the type-B carboxylesterase lipase family
IMZ18_00460	COG1396	sequence-specific DNA binding
IMZ18_00465	COG3944	biosynthesis protein
IMZ18_00470	COG0489	protein tyrosine kinase activity
IMZ18_00475	COG1086	Polysaccharide biosynthesis protein
IMZ18_00480	COG0438	transferase activity, transferring glycosyl groups
IMZ18_00485	COG1215	transferase activity, transferring glycosyl groups
IMZ18_00490	COG0438	transferase activity, transferring glycosyl groups
IMZ18_00500	COG1216	Glycosyl transferase, family 2
IMZ18_00505	COG5039	Polysaccharide pyruvyl transferase
IMZ18_00510	COG1216	Glycosyl transferase, family 2
IMZ18_00515	COG2244	polysaccharide biosynthetic process
IMZ18_00520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMZ18_00525	COG0110	maltose O-acetyltransferase activity
IMZ18_00530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMZ18_00535	COG5039	Polysaccharide pyruvyl transferase
IMZ18_00545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IMZ18_00550	COG1620	l-lactate permease
IMZ18_00555	COG2186	Transcriptional regulator
IMZ18_00560	COG1609	Transcriptional regulator
IMZ18_00565	COG2182	Extracellular solute-binding protein
IMZ18_00570	COG1175	transmembrane transport
IMZ18_00575	COG3833	ABC-type maltose transport systems, permease component
IMZ18_00580	COG1874	Beta-galactosidase
IMZ18_00585	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IMZ18_00590	COG2208	phosphoserine phosphatase activity
IMZ18_00595	COG0596	Alpha beta hydrolase
IMZ18_00615	COG1131	(ABC) transporter
IMZ18_00620	COG0842	Transport permease protein
IMZ18_00625	COG4585	Histidine kinase
IMZ18_00630	COG2197	response regulator
IMZ18_00635	COG0247	lactate metabolic process
IMZ18_00640	COG1139	Iron-sulfur cluster binding protein
IMZ18_00645	COG1556	Lactate utilization protein
IMZ18_00655	COG1113	amino acid transport
IMZ18_00660	COG0697	spore germination
IMZ18_00665	COG0583	DNA-binding transcription factor activity
IMZ18_00670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMZ18_00675	COG1609	Transcriptional regulator
IMZ18_00680	COG2814	Major facilitator Superfamily
IMZ18_00685	COG2390	Transcriptional regulator
IMZ18_00690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMZ18_00695	COG0126	phosphoglycerate kinase activity
IMZ18_00700	COG0149	triose-phosphate isomerase activity
IMZ18_00705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMZ18_00710	COG0148	phosphopyruvate hydratase activity
IMZ18_00715	COG0456	acetyltransferase
IMZ18_00720	COG4640	response to antibiotic
IMZ18_00725	COG3064	Membrane
IMZ18_00735	COG2095	MarC family integral membrane protein
IMZ18_00740	COG1510	regulation of RNA biosynthetic process
IMZ18_00745	COG1125	glycine betaine transport
IMZ18_00745	COG0517	IMP dehydrogenase activity
IMZ18_00750	COG1174	glycine betaine transport
IMZ18_00755	COG1732	Glycine betaine
IMZ18_00760	COG1174	glycine betaine transport
IMZ18_00765	COG1510	regulation of RNA biosynthetic process
IMZ18_00770	COG0517	IMP dehydrogenase activity
IMZ18_00770	COG1125	glycine betaine transport
IMZ18_00780	COG1732	Glycine betaine
IMZ18_00785	COG1174	glycine betaine transport
IMZ18_00790	COG0840	transmembrane signaling receptor activity
IMZ18_00795	COG1733	regulation of RNA biosynthetic process
IMZ18_00800	COG1396	sequence-specific DNA binding
IMZ18_00805	COG1396	sequence-specific DNA binding
IMZ18_00810	COG1476	TRANSCRIPTIONal
IMZ18_00815	COG0596	Alpha beta hydrolase
IMZ18_00820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMZ18_00825	COG1647	Serine aminopeptidase, S33
IMZ18_00830	COG0557	exoribonuclease II activity
IMZ18_00835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMZ18_01075	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMZ18_01075	COG3942	CHAP domain
IMZ18_01100	COG4824	toxin secretion phage lysis holin
IMZ18_01105	COG5632	N-Acetylmuramoyl-L-alanine amidase
IMZ18_01105	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_01120	COG5444	nuclease activity
IMZ18_01130	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_01135	COG1309	transcriptional regulator
IMZ18_01140	COG2076	Multidrug Resistance protein
IMZ18_01150	COG1289	transmembrane transporter activity
IMZ18_01160	COG0673	inositol 2-dehydrogenase activity
IMZ18_01165	COG1937	Protein conserved in bacteria
IMZ18_01170	COG2608	mercury ion transmembrane transporter activity
IMZ18_01175	COG2217	Heavy metal translocating P-type atpase
IMZ18_01180	COG2217	Heavy metal translocating P-type atpase
IMZ18_01185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IMZ18_01190	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IMZ18_01195	COG2860	membrane
IMZ18_01205	COG3973	AAA domain
IMZ18_01210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IMZ18_01215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMZ18_01220	COG0025	NhaP-type Na H and K H
IMZ18_01230	COG0656	L-ascorbic acid biosynthetic process
IMZ18_01235	COG4149	molybdate abc transporter
IMZ18_01240	COG0725	ABC transporter, periplasmic molybdate-binding protein
IMZ18_01245	COG1910	domain protein
IMZ18_01250	COG1368	sulfuric ester hydrolase activity
IMZ18_01255	COG1988	membrane-bound metal-dependent
IMZ18_01265	COG0531	amino acid
IMZ18_01270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ18_01275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ18_01280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ18_01285	COG1120	ATPase activity
IMZ18_01290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMZ18_01295	COG1136	(ABC) transporter
IMZ18_01300	COG0577	efflux transmembrane transporter activity
IMZ18_01310	COG2140	Oxalate decarboxylase
IMZ18_01330	COG0745	RESPONSE REGULATOR receiver
IMZ18_01335	COG2205	protein histidine kinase activity
IMZ18_01340	COG3386	PFAM SMP-30 Gluconolaconase
IMZ18_01345	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_01350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ18_01360	COG1120	ATPase activity
IMZ18_01365	COG2096	Adenosyltransferase
IMZ18_01370	COG2814	Major facilitator Superfamily
IMZ18_01375	COG4758	membrane
IMZ18_01380	COG1842	Phage shock protein A
IMZ18_01385	COG3595	metallopeptidase activity
IMZ18_01390	COG4758	membrane
IMZ18_01395	COG4585	Histidine kinase
IMZ18_01400	COG2197	response regulator
IMZ18_01410	COG0814	amino acid
IMZ18_01415	COG0697	spore germination
IMZ18_01425	COG0114	fumarate hydratase activity
IMZ18_01435	COG1309	transcriptional regulator
IMZ18_01445	COG2205	protein histidine kinase activity
IMZ18_01445	COG2770	Histidine kinase
IMZ18_01450	COG0745	RESPONSE REGULATOR receiver
IMZ18_01455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMZ18_01460	COG0783	Belongs to the Dps family
IMZ18_01505	COG1131	(ABC) transporter
IMZ18_01525	COG1120	ATPase activity
IMZ18_01535	COG0583	DNA-binding transcription factor activity
IMZ18_01540	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_01545	COG1942	4-Oxalocrotonate Tautomerase
IMZ18_01550	COG0477	Major facilitator Superfamily
IMZ18_01555	COG1846	Transcriptional regulator
IMZ18_01560	COG5577	PFAM Coat F domain
IMZ18_01580	COG1024	Enoyl-CoA hydratase
IMZ18_01580	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMZ18_01585	COG0183	Belongs to the thiolase family
IMZ18_01590	COG1960	acyl-CoA dehydrogenase activity
IMZ18_01595	COG1393	Belongs to the ArsC family
IMZ18_01600	COG0509	glycine decarboxylation via glycine cleavage system
IMZ18_01610	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMZ18_01615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_01625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMZ18_01630	COG2011	ABC-type metal ion transport system permease component
IMZ18_01635	COG1464	Belongs to the NlpA lipoprotein family
IMZ18_01650	COG0396	ATPase activity
IMZ18_01655	COG0719	Fe-S assembly protein
IMZ18_01660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMZ18_01665	COG0822	iron-sulfur transferase activity
IMZ18_01670	COG0719	Fe-S assembly protein
IMZ18_01675	COG0640	Transcriptional regulator
IMZ18_01680	COG0346	lactoylglutathione lyase activity
IMZ18_01695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMZ18_01700	COG0322	excinuclease ABC activity
IMZ18_01705	COG2222	sugar isomerase
IMZ18_01710	COG1653	transport
IMZ18_01715	COG1175	transmembrane transport
IMZ18_01725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ18_01730	COG2188	Transcriptional regulator
IMZ18_01735	COG3842	ATPase activity
IMZ18_01740	COG2356	endonuclease I
IMZ18_01750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMZ18_01755	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IMZ18_01760	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IMZ18_01765	COG2068	MobA-Related Protein
IMZ18_01770	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IMZ18_01775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IMZ18_01780	COG2080	2 iron, 2 sulfur cluster binding
IMZ18_01790	COG2351	hydroxyisourate hydrolase activity
IMZ18_01795	COG3648	Uricase
IMZ18_01795	COG3195	allantoin biosynthetic process
IMZ18_01800	COG2233	PERMEase
IMZ18_01805	COG2233	PERMEase
IMZ18_01810	COG2508	Transcriptional regulator
IMZ18_01825	COG1801	Protein of unknown function DUF72
IMZ18_01830	COG0730	response to heat
IMZ18_01835	COG0737	Belongs to the 5'-nucleotidase family
IMZ18_01840	COG3377	Domain of unknown function (DUF1805)
IMZ18_01850	COG0739	heme binding
IMZ18_01855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IMZ18_01865	COG4470	Protein conserved in bacteria
IMZ18_01870	COG2445	Protein of unknown function DUF86
IMZ18_01875	COG0647	UMP catabolic process
IMZ18_01880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IMZ18_01885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMZ18_01890	COG0460	homoserine dehydrogenase
IMZ18_01895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IMZ18_01900	COG0083	homoserine kinase activity
IMZ18_01905	COG0823	Involved in the tonB-independent uptake of proteins
IMZ18_01905	COG4946	Tricorn protease homolog
IMZ18_01905	COG1506	peptidase
IMZ18_01910	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IMZ18_01915	COG4837	Protein of unknown function (DUF1462)
IMZ18_01920	COG1252	NADH dehydrogenase
IMZ18_01925	COG4844	belongs to the
IMZ18_01930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMZ18_01935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IMZ18_01940	COG0316	Belongs to the HesB IscA family
IMZ18_01945	COG4974	Belongs to the 'phage' integrase family
IMZ18_01955	COG0582	viral genome integration into host DNA
IMZ18_02065	COG0456	acetyltransferase
IMZ18_02070	COG2808	Putative FMN-binding domain
IMZ18_02075	COG0516	GMP reductase activity
IMZ18_02085	COG0492	ferredoxin-NADP+ reductase activity
IMZ18_02090	COG1252	NADH dehydrogenase
IMZ18_02105	COG3584	3D domain protein
IMZ18_02110	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IMZ18_02115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IMZ18_02120	COG2056	Na+-H+ antiporter family
IMZ18_02125	COG1268	BioY protein
IMZ18_02130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMZ18_02135	COG2819	hydrolase of the alpha beta superfamily
IMZ18_02140	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_02145	COG1169	isochorismate synthase
IMZ18_02150	COG1021	2,3-dihydroxybenzoate-AMP ligase
IMZ18_02155	COG1535	isochorismatase
IMZ18_02155	COG3433	isochorismatase activity
IMZ18_02160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMZ18_02165	COG3251	PFAM MbtH domain protein
IMZ18_02170	COG5634	Uncharacterized conserved protein (DUF2278)
IMZ18_02175	COG0686	Belongs to the AlaDH PNT family
IMZ18_02180	COG2508	Transcriptional regulator
IMZ18_02180	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IMZ18_02185	COG4842	Belongs to the WXG100 family
IMZ18_02190	COG5417	Belongs to the EsaB family
IMZ18_02195	COG4499	WXG100 protein secretion system (Wss), protein YukC
IMZ18_02200	COG1674	ftsk spoiiie
IMZ18_02200	COG0433	COG0433 Predicted ATPase
IMZ18_02205	COG1511	domain protein
IMZ18_02215	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_02220	COG1418	mRNA catabolic process
IMZ18_02235	COG0628	permease
IMZ18_02250	COG5506	Protein of unknown function (DUF1694)
IMZ18_02255	COG1335	isochorismatase
IMZ18_02260	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMZ18_02265	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IMZ18_02285	COG0142	geranyltranstransferase activity
IMZ18_02295	COG4585	Histidine kinase
IMZ18_02300	COG2197	response regulator
IMZ18_02305	COG2050	protein possibly involved in aromatic compounds catabolism
IMZ18_02310	COG1320	monovalent cation:proton antiporter activity
IMZ18_02315	COG2212	antiporter activity
IMZ18_02320	COG1863	multisubunit Na H antiporter MnhE subunit
IMZ18_02325	COG0651	ATP synthesis coupled electron transport
IMZ18_02330	COG1006	Multisubunit Na H antiporter MnhC subunit
IMZ18_02335	COG2111	Na H antiporter
IMZ18_02340	COG2111	Na H antiporter
IMZ18_02340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMZ18_02350	COG3493	citrate carrier protein
IMZ18_02355	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMZ18_02360	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMZ18_02365	COG3845	ABC transporter
IMZ18_02370	COG1744	ABC transporter substrate-binding protein PnrA-like
IMZ18_02375	COG4565	transcriptional regulatory protein
IMZ18_02380	COG3290	protein histidine kinase activity
IMZ18_02390	COG3011	Protein conserved in bacteria
IMZ18_02395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMZ18_02400	COG2814	Major facilitator Superfamily
IMZ18_02405	COG5018	Exonuclease
IMZ18_02415	COG2205	protein histidine kinase activity
IMZ18_02420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IMZ18_02430	COG2267	carboxylic ester hydrolase activity
IMZ18_02435	COG1522	sequence-specific DNA binding
IMZ18_02440	COG0436	Aminotransferase
IMZ18_02445	COG1098	S1 RNA binding domain
IMZ18_02450	COG2155	Conserved Protein
IMZ18_02455	COG1979	alcohol dehydrogenase
IMZ18_02460	COG1979	alcohol dehydrogenase
IMZ18_02465	COG0166	Belongs to the GPI family
IMZ18_02480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IMZ18_02495	COG2738	Putative neutral zinc metallopeptidase
IMZ18_02500	COG1253	flavin adenine dinucleotide binding
IMZ18_02505	COG0366	Alpha amylase catalytic
IMZ18_02515	COG0432	Pfam Uncharacterised protein family UPF0047
IMZ18_02540	COG0840	transmembrane signaling receptor activity
IMZ18_02550	COG3347	Dehydrogenase
IMZ18_02550	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_02555	COG1349	DNA-binding transcription factor activity
IMZ18_02560	COG1070	Carbohydrate kinase
IMZ18_02565	COG3254	rhamnose metabolic process
IMZ18_02570	COG4806	L-rhamnose isomerase
IMZ18_02575	COG0673	inositol 2-dehydrogenase activity
IMZ18_02580	COG0628	permease
IMZ18_02585	COG1968	undecaprenyl-diphosphatase activity
IMZ18_02600	COG5553	Cysteine dioxygenase type I
IMZ18_02605	COG0477	Major facilitator Superfamily
IMZ18_02610	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMZ18_02615	COG4682	membrane
IMZ18_02620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMZ18_02625	COG0569	domain protein
IMZ18_02635	COG1510	regulation of RNA biosynthetic process
IMZ18_02640	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_02645	COG1454	alcohol dehydrogenase
IMZ18_02655	COG2318	DinB family
IMZ18_02660	COG1585	Membrane protein implicated in regulation of membrane protease activity
IMZ18_02665	COG2268	Band 7 protein
IMZ18_02670	COG1247	-acetyltransferase
IMZ18_02675	COG3859	Proton-coupled thiamine transporter YuaJ
IMZ18_02800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IMZ18_02805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMZ18_02810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMZ18_02815	COG0297	glycogen (starch) synthase activity
IMZ18_02825	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IMZ18_02830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMZ18_02835	COG0438	transferase activity, transferring glycosyl groups
IMZ18_02840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMZ18_02850	COG0438	transferase activity, transferring glycosyl groups
IMZ18_02855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMZ18_02860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMZ18_02870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IMZ18_02875	COG1169	isochorismate synthase
IMZ18_02885	COG0596	Alpha beta hydrolase
IMZ18_02890	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IMZ18_02895	COG0318	PFAM AMP-dependent synthetase and ligase
IMZ18_02900	COG4948	Mandelate Racemase Muconate Lactonizing
IMZ18_02905	COG0803	Belongs to the bacterial solute-binding protein 9 family
IMZ18_02910	COG1121	(ABC) transporter
IMZ18_02915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMZ18_02915	COG1321	iron dependent repressor
IMZ18_02920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMZ18_02930	COG1294	oxidase, subunit
IMZ18_02935	COG1271	oxidase subunit
IMZ18_02940	COG0254	rRNA binding
IMZ18_02945	COG0288	reversible hydration of carbon dioxide
IMZ18_02950	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMZ18_02955	COG1854	S-ribosylhomocysteine lyase activity
IMZ18_02970	COG0783	Belongs to the Dps family
IMZ18_02975	COG4824	toxin secretion phage lysis holin
IMZ18_02980	COG0494	nUDIX hydrolase
IMZ18_02985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMZ18_02990	COG1116	anion transmembrane transporter activity
IMZ18_02995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMZ18_03000	COG1506	peptidase
IMZ18_03010	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IMZ18_03015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMZ18_03020	COG0367	asparagine synthase
IMZ18_03025	COG1113	amino acid transport
IMZ18_03030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IMZ18_03035	COG2267	carboxylic ester hydrolase activity
IMZ18_03045	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IMZ18_03050	COG1242	4 iron, 4 sulfur cluster binding
IMZ18_03070	COG1725	Transcriptional regulator
IMZ18_03075	COG1131	(ABC) transporter
IMZ18_03090	COG1136	(ABC) transporter
IMZ18_03095	COG0577	efflux transmembrane transporter activity
IMZ18_03100	COG0745	RESPONSE REGULATOR receiver
IMZ18_03105	COG2205	protein histidine kinase activity
IMZ18_03110	COG1136	(ABC) transporter
IMZ18_03115	COG0577	efflux transmembrane transporter activity
IMZ18_03120	COG2433	Pfam Transposase IS66
IMZ18_03125	COG2814	Major facilitator Superfamily
IMZ18_03130	COG2202	Pas domain
IMZ18_03130	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_03140	COG0495	leucyl-tRNA aminoacylation
IMZ18_03145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMZ18_03150	COG1486	melibiose metabolic process
IMZ18_03155	COG0395	ABC-type sugar transport system, permease component
IMZ18_03160	COG1175	transmembrane transport
IMZ18_03165	COG1653	transport
IMZ18_03175	COG1073	alpha beta
IMZ18_03185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMZ18_03205	COG2124	cytochrome p450
IMZ18_03210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMZ18_03215	COG0395	ABC-type sugar transport system, permease component
IMZ18_03220	COG1653	transport
IMZ18_03230	COG4209	transmembrane transport
IMZ18_03235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IMZ18_03240	COG1653	transport
IMZ18_03260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IMZ18_03265	COG2081	HI0933 family
IMZ18_03270	COG2244	polysaccharide biosynthetic process
IMZ18_03275	COG1187	pseudouridine synthase activity
IMZ18_03280	COG1349	DNA-binding transcription factor activity
IMZ18_03285	COG1131	(ABC) transporter
IMZ18_03290	COG4473	ABC transporter
IMZ18_03295	COG2252	PERMEase
IMZ18_03300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMZ18_03305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMZ18_03310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IMZ18_03320	COG1597	lipid kinase activity
IMZ18_03325	COG1523	belongs to the glycosyl hydrolase 13 family
IMZ18_03330	COG0510	thiamine kinase activity
IMZ18_03340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMZ18_03345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ18_03350	COG0281	malic enzyme
IMZ18_03355	COG5584	Small secreted protein
IMZ18_03360	COG1363	Peptidase, m42
IMZ18_03375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_03380	COG4848	Belongs to the UPF0354 family
IMZ18_03385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ18_03390	COG1674	ftsk spoiiie
IMZ18_03395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMZ18_03400	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMZ18_03405	COG4980	gas vesicle protein
IMZ18_03410	COG3118	belongs to the thioredoxin family
IMZ18_03415	COG1605	Chorismate mutase
IMZ18_03415	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IMZ18_03420	COG1609	Transcriptional regulator
IMZ18_03425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IMZ18_03430	COG1360	Flagellar Motor Protein
IMZ18_03435	COG0123	including yeast histone deacetylase and acetoin utilization protein
IMZ18_03440	COG0517	IMP dehydrogenase activity
IMZ18_03445	COG0454	-acetyltransferase
IMZ18_03450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMZ18_03455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMZ18_03460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMZ18_03465	COG2203	Gaf domain
IMZ18_03465	COG2199	diguanylate cyclase activity
IMZ18_03470	COG1956	GAF domain-containing protein
IMZ18_03475	COG1309	transcriptional regulator
IMZ18_03480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IMZ18_03485	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMZ18_03490	COG1114	Component of the transport system for branched-chain amino acids
IMZ18_03495	COG1104	cysteine desulfurase activity
IMZ18_03500	COG0301	tRNA thio-modification
IMZ18_03510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IMZ18_03515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IMZ18_03520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMZ18_03525	COG0616	signal peptide processing
IMZ18_03530	COG1714	RDD family
IMZ18_03540	COG3874	Sporulation protein YtfJ
IMZ18_03545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMZ18_03550	COG0827	DNA restriction-modification system
IMZ18_03560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMZ18_03565	COG0521	Mo-molybdopterin cofactor biosynthetic process
IMZ18_03570	COG0137	argininosuccinate synthase activity
IMZ18_03575	COG0165	Argininosuccinate lyase
IMZ18_03580	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_03585	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IMZ18_03595	COG4109	DRTGG domain
IMZ18_03605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IMZ18_03625	COG0587	DNA-directed DNA polymerase activity
IMZ18_03630	COG0281	malic enzyme
IMZ18_03635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMZ18_03640	COG0825	malonyl-CoA metabolic process
IMZ18_03645	COG0205	6-phosphofructokinase activity
IMZ18_03650	COG0469	pyruvate kinase activity
IMZ18_03655	COG3030	protein affecting phage T7 exclusion by the F plasmid
IMZ18_03660	COG0628	permease
IMZ18_03665	COG2707	UPF0756 membrane protein
IMZ18_03670	COG0372	Belongs to the citrate synthase family
IMZ18_03675	COG0538	isocitrate dehydrogenase activity
IMZ18_03680	COG0039	L-malate dehydrogenase activity
IMZ18_03685	COG0745	RESPONSE REGULATOR receiver
IMZ18_03690	COG5002	protein histidine kinase activity
IMZ18_03695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMZ18_03695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMZ18_03700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMZ18_03705	COG1971	Probably functions as a manganese efflux pump
IMZ18_03710	COG0237	dephospho-CoA kinase activity
IMZ18_03715	COG0656	L-ascorbic acid biosynthetic process
IMZ18_03720	COG2814	Major facilitator Superfamily
IMZ18_03725	COG1733	regulation of RNA biosynthetic process
IMZ18_03730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IMZ18_03735	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IMZ18_03740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IMZ18_03745	COG3611	Membrane attachment protein
IMZ18_03750	COG1484	DNA-dependent DNA replication
IMZ18_03755	COG0398	Pfam SNARE associated Golgi protein
IMZ18_03765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMZ18_03770	COG1011	Hydrolase
IMZ18_03775	COG3275	phosphorelay sensor kinase activity
IMZ18_03780	COG3279	Response regulator of the LytR AlgR family
IMZ18_03785	COG1380	Effector of murein hydrolase LrgA
IMZ18_03790	COG1346	cytolysis
IMZ18_03800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMZ18_03805	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IMZ18_03810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMZ18_03815	COG3326	Membrane
IMZ18_03825	COG1363	Peptidase, m42
IMZ18_03835	COG2160	L-arabinose isomerase activity
IMZ18_03840	COG1069	ribulokinase activity
IMZ18_03845	COG0235	Class ii aldolase
IMZ18_03850	COG0647	UMP catabolic process
IMZ18_03855	COG0371	Dehydrogenase
IMZ18_03860	COG1653	transport
IMZ18_03865	COG1175	transmembrane transport
IMZ18_03870	COG0395	ABC-type sugar transport system, permease component
IMZ18_03875	COG3534	alpha-L-arabinofuranosidase
IMZ18_03880	COG1966	Carbon starvation protein
IMZ18_03885	COG0346	lactoylglutathione lyase activity
IMZ18_03890	COG0247	lactate metabolic process
IMZ18_03900	COG3835	regulator
IMZ18_03910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMZ18_03920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMZ18_03925	COG0072	phenylalanine-tRNA ligase activity
IMZ18_03925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ18_03930	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMZ18_03935	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IMZ18_03940	COG1286	toxin biosynthetic process
IMZ18_03945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IMZ18_03945	COG1796	DNA polymerase
IMZ18_03950	COG1193	negative regulation of DNA recombination
IMZ18_03955	COG3766	membrane
IMZ18_03960	COG0318	PFAM AMP-dependent synthetase and ligase
IMZ18_03965	COG1309	transcriptional regulator
IMZ18_03970	COG1024	Enoyl-CoA hydratase
IMZ18_03975	COG2086	electron transfer activity
IMZ18_03980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IMZ18_03985	COG3534	alpha-L-arabinofuranosidase
IMZ18_03990	COG3118	belongs to the thioredoxin family
IMZ18_03995	COG0322	excinuclease ABC activity
IMZ18_04000	COG0527	aspartate kinase activity
IMZ18_04005	COG1719	4-vinyl reductase, 4VR
IMZ18_04010	COG2009	succinate dehydrogenase
IMZ18_04015	COG1053	succinate dehydrogenase
IMZ18_04020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IMZ18_04025	COG0824	Thioesterase
IMZ18_04030	COG2197	response regulator
IMZ18_04035	COG1846	Transcriptional regulator
IMZ18_04040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMZ18_04045	COG5401	PFAM Sporulation and spore germination
IMZ18_04050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IMZ18_04055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMZ18_04060	COG0622	Phosphoesterase
IMZ18_04090	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IMZ18_04115	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
IMZ18_04130	COG0028	Belongs to the TPP enzyme family
IMZ18_04135	COG0440	acetolactate synthase activity
IMZ18_04140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IMZ18_04145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMZ18_04150	COG0473	3-isopropylmalate dehydrogenase activity
IMZ18_04155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IMZ18_04160	COG0066	3-isopropylmalate dehydratase activity
IMZ18_04165	COG1477	protein flavinylation
IMZ18_04165	COG0457	Tetratricopeptide repeat
IMZ18_04170	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMZ18_04175	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMZ18_04180	COG1067	ATP-dependent peptidase activity
IMZ18_04180	COG0470	DNA polymerase III
IMZ18_04185	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IMZ18_04190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IMZ18_04200	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IMZ18_04205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMZ18_04210	COG0181	hydroxymethylbilane synthase activity
IMZ18_04215	COG1587	Uroporphyrinogen-III synthase
IMZ18_04220	COG0113	porphobilinogen synthase activity
IMZ18_04225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMZ18_04230	COG1388	LysM domain
IMZ18_04235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMZ18_04245	COG0525	valine-tRNA ligase activity
IMZ18_04255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IMZ18_04265	COG0424	maF-like protein
IMZ18_04270	COG2003	Belongs to the UPF0758 family
IMZ18_04275	COG1077	Cell shape determining protein MreB Mrl
IMZ18_04285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IMZ18_04290	COG0850	regulation of cytokinetic process
IMZ18_04295	COG2894	cell division
IMZ18_04300	COG0739	heme binding
IMZ18_04305	COG1994	Peptidase M50
IMZ18_04310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IMZ18_04315	COG2868	ribosomal protein
IMZ18_04320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IMZ18_04330	COG3290	protein histidine kinase activity
IMZ18_04335	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IMZ18_04340	COG4492	Belongs to the UPF0735 family
IMZ18_04345	COG0077	Prephenate dehydratase
IMZ18_04350	COG1827	regulation of RNA biosynthetic process
IMZ18_04355	COG1104	cysteine desulfurase activity
IMZ18_04360	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IMZ18_04365	COG0157	Belongs to the NadC ModD family
IMZ18_04370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IMZ18_04375	COG1388	LysM domain
IMZ18_04385	COG0217	transcriptional regulatory protein
IMZ18_04390	COG1115	amino acid carrier protein
IMZ18_04410	COG2112	serine threonine protein kinase
IMZ18_04415	COG0673	inositol 2-dehydrogenase activity
IMZ18_04420	COG2814	Major facilitator Superfamily
IMZ18_04430	COG0632	four-way junction helicase activity
IMZ18_04435	COG2255	four-way junction helicase activity
IMZ18_04445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMZ18_04450	COG0343	queuine tRNA-ribosyltransferase activity
IMZ18_04465	COG2323	membrane
IMZ18_04470	COG2244	polysaccharide biosynthetic process
IMZ18_04480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMZ18_04480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IMZ18_04485	COG0490	domain, Protein
IMZ18_04490	COG5416	Lipopolysaccharide assembly protein A domain
IMZ18_04495	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IMZ18_04495	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IMZ18_04500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMZ18_04505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMZ18_04510	COG1490	D-aminoacyl-tRNA deacylase activity
IMZ18_04515	COG3103	Sh3 type 3 domain protein
IMZ18_04515	COG4991	sh3 domain protein
IMZ18_04515	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMZ18_04525	COG0124	histidyl-tRNA synthetase
IMZ18_04530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMZ18_04540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IMZ18_04550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMZ18_04555	COG1959	2 iron, 2 sulfur cluster binding
IMZ18_04560	COG1104	cysteine desulfurase activity
IMZ18_04565	COG0482	sulfurtransferase activity
IMZ18_04570	COG0457	Tetratricopeptide repeat
IMZ18_04575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMZ18_04580	COG3881	PFAM PRC-barrel domain
IMZ18_04595	COG0765	amino acid transport
IMZ18_04600	COG0765	amino acid transport
IMZ18_04605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMZ18_04610	COG1126	abc transporter atp-binding protein
IMZ18_04615	COG0628	permease
IMZ18_04620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMZ18_04625	COG4472	Bacterial protein of unknown function (DUF965)
IMZ18_04630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMZ18_04635	COG3906	Belongs to the UPF0473 family
IMZ18_04640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMZ18_04645	COG4122	O-methyltransferase activity
IMZ18_04650	COG0826	peptidase U32
IMZ18_04655	COG0826	peptidase U32
IMZ18_04660	COG0572	uridine kinase
IMZ18_04665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMZ18_04670	COG0768	penicillin binding
IMZ18_04685	COG2226	methyltransferase
IMZ18_04690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IMZ18_04695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMZ18_04700	COG0626	cystathionine gamma-synthase activity
IMZ18_04715	COG2427	Protein of unknown function (DUF1641)
IMZ18_04720	COG3383	formate dehydrogenase (NAD+) activity
IMZ18_04725	COG5609	conserved protein (DUF2294)
IMZ18_04730	COG2116	formate transmembrane transporter activity
IMZ18_04745	COG2226	methyltransferase
IMZ18_04750	COG1309	transcriptional regulator
IMZ18_04775	COG1595	DNA-templated transcription, initiation
IMZ18_04780	COG1378	Sugar-specific transcriptional regulator TrmB
IMZ18_04785	COG1280	lysine exporter protein (LysE YggA)
IMZ18_04790	COG1113	amino acid transport
IMZ18_04800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IMZ18_04800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IMZ18_04805	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_04810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_04815	COG3715	PTS system
IMZ18_04820	COG3716	PTS system mannose fructose sorbose family IID component
IMZ18_04825	COG1621	beta-fructofuranosidase activity
IMZ18_04830	COG0693	protein deglycase activity
IMZ18_04835	COG1064	alcohol dehydrogenase
IMZ18_04845	COG0789	Transcriptional regulator
IMZ18_04850	COG5577	PFAM Coat F domain
IMZ18_04860	COG1063	alcohol dehydrogenase
IMZ18_04865	COG5577	PFAM Coat F domain
IMZ18_04875	COG0346	lactoylglutathione lyase activity
IMZ18_04885	COG4991	sh3 domain protein
IMZ18_04890	COG4991	sh3 domain protein
IMZ18_04900	COG5566	PFAM Mor transcription activator
IMZ18_04905	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_04910	COG0667	Aldo Keto reductase
IMZ18_04915	COG1595	DNA-templated transcription, initiation
IMZ18_04920	COG3443	Belongs to the bacterial solute-binding protein 9 family
IMZ18_04940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IMZ18_04945	COG2070	2-Nitropropane dioxygenase
IMZ18_04955	COG2318	DinB family
IMZ18_04975	COG1335	isochorismatase
IMZ18_04990	COG2124	cytochrome p450
IMZ18_04995	COG2732	(Barnase) inhibitor
IMZ18_05000	COG1522	sequence-specific DNA binding
IMZ18_05015	COG1114	Component of the transport system for branched-chain amino acids
IMZ18_05025	COG1230	cation diffusion facilitator family transporter
IMZ18_05030	COG2072	flavoprotein involved in K transport
IMZ18_05035	COG0583	DNA-binding transcription factor activity
IMZ18_05040	COG0697	spore germination
IMZ18_05050	COG1253	flavin adenine dinucleotide binding
IMZ18_05055	COG0456	acetyltransferase
IMZ18_05060	COG2814	Major facilitator Superfamily
IMZ18_05065	COG4978	Transcriptional regulator
IMZ18_05065	COG0789	Transcriptional regulator
IMZ18_05190	COG0457	Tetratricopeptide repeat
IMZ18_05200	COG0583	DNA-binding transcription factor activity
IMZ18_05205	COG0114	fumarate hydratase activity
IMZ18_05225	COG3209	COG3209 Rhs family protein
IMZ18_05235	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IMZ18_05240	COG0398	Pfam SNARE associated Golgi protein
IMZ18_05245	COG5632	N-Acetylmuramoyl-L-alanine amidase
IMZ18_05245	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_05250	COG2755	lipolytic protein G-D-S-L family
IMZ18_05260	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IMZ18_05265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMZ18_05270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMZ18_05275	COG1534	Rna-binding protein
IMZ18_05280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMZ18_05285	COG1713	HD superfamily hydrolase involved in NAD metabolism
IMZ18_05290	COG0799	negative regulation of ribosome biogenesis
IMZ18_05295	COG2226	methyltransferase
IMZ18_05300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMZ18_05305	COG1555	photosystem II stabilization
IMZ18_05305	COG1596	polysaccharide export
IMZ18_05310	COG2131	deaminase
IMZ18_05315	COG0658	competence protein
IMZ18_05315	COG2333	competence protein COMEC
IMZ18_05330	COG1466	dna polymerase III delta subunit
IMZ18_05335	COG0268	Binds directly to 16S ribosomal RNA
IMZ18_05340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IMZ18_05345	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMZ18_05355	COG0481	GTPase activity
IMZ18_05360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMZ18_05365	COG1420	regulation of RNA biosynthetic process
IMZ18_05370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMZ18_05380	COG0484	heat shock protein binding
IMZ18_05385	COG2264	protein methyltransferase activity
IMZ18_05390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMZ18_05395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ18_05400	COG1283	sodium-dependent phosphate transmembrane transporter activity
IMZ18_05410	COG1610	YqeY-like protein
IMZ18_05415	COG1030	water channel activity
IMZ18_05420	COG4864	UPF0365 protein
IMZ18_05435	COG0561	phosphatase activity
IMZ18_05440	COG1702	phosphate starvation-inducible protein PhoH
IMZ18_05445	COG1480	7TM receptor with intracellular HD hydrolase
IMZ18_05450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMZ18_05455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IMZ18_05460	COG0295	cytidine deaminase activity
IMZ18_05465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMZ18_05475	COG1381	Involved in DNA repair and RecF pathway recombination
IMZ18_05480	COG0752	glycyl-tRNA synthetase alpha subunit
IMZ18_05485	COG0751	glycine-tRNA ligase activity
IMZ18_05490	COG0517	IMP dehydrogenase activity
IMZ18_05495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IMZ18_05500	COG1671	Belongs to the UPF0178 family
IMZ18_05505	COG0358	DNA primase activity
IMZ18_05510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMZ18_05515	COG2010	Cytochrome c
IMZ18_05520	COG2384	SAM-dependent methyltransferase
IMZ18_05525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMZ18_05530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IMZ18_05540	COG0513	Belongs to the DEAD box helicase family
IMZ18_05545	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IMZ18_05555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMZ18_05560	COG0735	belongs to the Fur family
IMZ18_05565	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
IMZ18_05570	COG4709	membrane
IMZ18_05575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IMZ18_05580	COG1388	LysM domain
IMZ18_05585	COG5521	maltodextrose utilization protein MalA
IMZ18_05590	COG2839	Protein conserved in bacteria
IMZ18_05595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMZ18_05600	COG0477	Major facilitator Superfamily
IMZ18_05605	COG0768	penicillin binding
IMZ18_05610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMZ18_05615	COG0573	inorganic phosphate transmembrane transporter activity
IMZ18_05620	COG0581	inorganic phosphate transmembrane transporter activity
IMZ18_05625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMZ18_05630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMZ18_05635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMZ18_05650	COG0438	transferase activity, transferring glycosyl groups
IMZ18_05660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMZ18_05670	COG0457	Tetratricopeptide repeat
IMZ18_05670	COG0705	Rhomboid family
IMZ18_05675	COG4483	Protein conserved in bacteria
IMZ18_05680	COG1940	carbohydrate kinase activity
IMZ18_05685	COG1368	sulfuric ester hydrolase activity
IMZ18_05690	COG2866	Carboxypeptidase
IMZ18_05700	COG0011	TIGRFAM Protein of
IMZ18_05710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ18_05720	COG1393	Belongs to the ArsC family
IMZ18_05730	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_05735	COG1253	flavin adenine dinucleotide binding
IMZ18_05740	COG0598	Magnesium transport protein CorA
IMZ18_05745	COG0517	IMP dehydrogenase activity
IMZ18_05750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMZ18_05755	COG1459	type II secretion system
IMZ18_05760	COG4537	Required for transformation and DNA binding
IMZ18_05765	COG4970	Tfp pilus assembly protein FimT
IMZ18_05775	COG4940	Competence protein ComGF
IMZ18_05800	COG0681	Belongs to the peptidase S26 family
IMZ18_05810	COG1396	sequence-specific DNA binding
IMZ18_05825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMZ18_05830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IMZ18_05835	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMZ18_05840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IMZ18_05845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMZ18_05850	COG0095	Lipoate-protein ligase
IMZ18_05855	COG1321	iron dependent repressor
IMZ18_05860	COG1752	Esterase of the alpha-beta hydrolase superfamily
IMZ18_05870	COG3872	metal-dependent enzyme
IMZ18_05880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IMZ18_05885	COG0006	proline dipeptidase activity
IMZ18_05890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMZ18_05900	COG3854	ATPases associated with a variety of cellular activities
IMZ18_05945	COG0511	ligase activity, forming carbon-carbon bonds
IMZ18_05950	COG0439	Biotin carboxylase
IMZ18_05955	COG1302	Protein conserved in bacteria
IMZ18_05960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMZ18_05965	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMZ18_05970	COG1570	exodeoxyribonuclease VII activity
IMZ18_05975	COG1722	exodeoxyribonuclease VII activity
IMZ18_05980	COG0142	geranyltranstransferase activity
IMZ18_05985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IMZ18_05990	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IMZ18_05995	COG1438	arginine binding
IMZ18_06000	COG0497	DNA recombination
IMZ18_06005	COG0750	zinc metalloprotease
IMZ18_06010	COG0745	RESPONSE REGULATOR receiver
IMZ18_06015	COG1902	pentaerythritol trinitrate reductase activity
IMZ18_06030	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMZ18_06035	COG0584	glycerophosphoryl diester phosphodiesterase
IMZ18_06045	COG1250	3-hydroxyacyl-CoA dehydrogenase
IMZ18_06050	COG1960	acyl-CoA dehydrogenase activity
IMZ18_06055	COG0372	Belongs to the citrate synthase family
IMZ18_06060	COG2079	MmgE PrpD family protein
IMZ18_06065	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IMZ18_06075	COG3829	transcription factor binding
IMZ18_06075	COG3290	protein histidine kinase activity
IMZ18_06080	COG0280	phosphate acetyltransferase
IMZ18_06085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMZ18_06090	COG3426	butyrate kinase activity
IMZ18_06095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ18_06100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMZ18_06105	COG0022	dehydrogenase e1 component
IMZ18_06110	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMZ18_06115	COG4978	Transcriptional regulator
IMZ18_06115	COG0789	Transcriptional regulator
IMZ18_06125	COG1597	lipid kinase activity
IMZ18_06135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMZ18_06140	COG0765	amino acid transport
IMZ18_06145	COG1126	abc transporter atp-binding protein
IMZ18_06150	COG4129	membrane
IMZ18_06155	COG1376	ErfK ybiS ycfS ynhG family protein
IMZ18_06165	COG0346	lactoylglutathione lyase activity
IMZ18_06175	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMZ18_06180	COG3361	conserved protein (COG2071)
IMZ18_06185	COG0706	membrane insertase activity
IMZ18_06195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMZ18_06200	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMZ18_06205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMZ18_06210	COG1234	tRNA 3'-trailer cleavage
IMZ18_06220	COG0596	Alpha beta hydrolase
IMZ18_06230	COG1902	pentaerythritol trinitrate reductase activity
IMZ18_06240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMZ18_06245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ18_06250	COG0300	oxidoreductase activity
IMZ18_06255	COG3048	D-serine ammonia-lyase activity
IMZ18_06260	COG1072	(Pantothenic acid kinase))
IMZ18_06265	COG0346	lactoylglutathione lyase activity
IMZ18_06275	COG2211	Major facilitator Superfamily
IMZ18_06285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMZ18_06295	COG0456	acetyltransferase
IMZ18_06300	COG2329	Antibiotic biosynthesis monooxygenase
IMZ18_06305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IMZ18_06305	COG0456	acetyltransferase
IMZ18_06310	COG4918	Iron-sulphur cluster biosynthesis
IMZ18_06320	COG1073	alpha beta
IMZ18_06330	COG0667	Aldo Keto reductase
IMZ18_06340	COG0494	nUDIX hydrolase
IMZ18_06345	COG1379	DNA repair
IMZ18_06350	COG1396	sequence-specific DNA binding
IMZ18_06355	COG0252	asparaginase activity
IMZ18_06360	COG1027	Aspartate ammonia-lyase
IMZ18_06365	COG1757	Na H antiporter
IMZ18_06370	COG0281	malic enzyme
IMZ18_06380	COG1300	Membrane
IMZ18_06385	COG0735	belongs to the Fur family
IMZ18_06395	COG4974	Belongs to the 'phage' integrase family
IMZ18_06400	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IMZ18_06405	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IMZ18_06410	COG1686	Belongs to the peptidase S11 family
IMZ18_06415	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_06420	COG2172	sigma factor antagonist activity
IMZ18_06425	COG1191	sigma factor activity
IMZ18_06445	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMZ18_06460	COG0697	spore germination
IMZ18_06465	COG0019	diaminopimelate decarboxylase activity
IMZ18_06470	COG4086	secreted protein
IMZ18_06480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMZ18_06530	COG3328	transposase activity
IMZ18_06585	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IMZ18_06595	COG0681	Belongs to the peptidase S26 family
IMZ18_06605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMZ18_06605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IMZ18_06610	COG0307	riboflavin synthase, alpha
IMZ18_06615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMZ18_06615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMZ18_06620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IMZ18_06625	COG0456	acetyltransferase
IMZ18_06630	COG1547	Domain of unknown function (DUF309)
IMZ18_06635	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMZ18_06640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMZ18_06655	COG1686	Belongs to the peptidase S11 family
IMZ18_06660	COG2715	membrane protein required for spore maturation
IMZ18_06665	COG0700	Nucleoside recognition
IMZ18_06670	COG1187	pseudouridine synthase activity
IMZ18_06675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_06680	COG1333	cytochrome c biogenesis protein
IMZ18_06685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IMZ18_06690	COG0745	RESPONSE REGULATOR receiver
IMZ18_06695	COG5002	protein histidine kinase activity
IMZ18_06700	COG1595	DNA-templated transcription, initiation
IMZ18_06710	COG0710	3-dehydroquinate dehydratase activity
IMZ18_06715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IMZ18_06720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IMZ18_06730	COG1141	Ferredoxin
IMZ18_06735	COG4955	Helix-turn-helix domain
IMZ18_06745	COG1266	CAAX protease self-immunity
IMZ18_06750	COG1388	LysM domain
IMZ18_06760	COG1408	metallophosphoesterase
IMZ18_06765	COG4862	establishment of competence for transformation
IMZ18_06770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMZ18_06775	COG0492	ferredoxin-NADP+ reductase activity
IMZ18_06780	COG2339	peptidase activity
IMZ18_06785	COG3773	Cell wall hydrolase
IMZ18_06785	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_06790	COG2959	enzyme of heme biosynthesis
IMZ18_06795	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IMZ18_06805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMZ18_06810	COG0539	negative regulation of cytoplasmic translation
IMZ18_06815	COG1304	FMN binding
IMZ18_06840	COG1160	GTP binding
IMZ18_06845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMZ18_06860	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IMZ18_06865	COG0776	regulation of translation
IMZ18_06870	COG0302	gtp cyclohydrolase
IMZ18_06880	COG0142	geranyltranstransferase activity
IMZ18_06885	COG2226	methyltransferase
IMZ18_06890	COG0142	geranyltranstransferase activity
IMZ18_06895	COG0105	UTP biosynthetic process
IMZ18_06900	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IMZ18_06905	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMZ18_06910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IMZ18_06915	COG4401	Chorismate mutase type I
IMZ18_06920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMZ18_06925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMZ18_06935	COG0135	phosphoribosylanthranilate isomerase activity
IMZ18_06940	COG0133	tryptophan synthase activity
IMZ18_06955	COG0287	Prephenate dehydrogenase
IMZ18_06960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IMZ18_06965	COG0457	Tetratricopeptide repeat
IMZ18_06970	COG5582	Belongs to the UPF0302 family
IMZ18_06980	COG0723	plastoquinol--plastocyanin reductase activity
IMZ18_06985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IMZ18_06990	COG2010	Cytochrome c
IMZ18_06990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IMZ18_06995	COG4347	Protein of unknown function (DUF1405)
IMZ18_07005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMZ18_07010	COG1694	Mazg nucleotide pyrophosphohydrolase
IMZ18_07015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMZ18_07020	COG1803	Methylglyoxal synthase
IMZ18_07025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMZ18_07030	COG0438	transferase activity, transferring glycosyl groups
IMZ18_07035	COG0617	tRNA 3'-terminal CCA addition
IMZ18_07040	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IMZ18_07040	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IMZ18_07045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IMZ18_07050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IMZ18_07055	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IMZ18_07060	COG1199	ATP-dependent helicase activity
IMZ18_07060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMZ18_07070	COG5353	protein conserved in bacteria
IMZ18_07075	COG0436	Aminotransferase
IMZ18_07080	COG0017	Asparaginyl-tRNA synthetase
IMZ18_07085	COG3935	DnaD domain protein
IMZ18_07090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMZ18_07100	COG4499	WXG100 protein secretion system (Wss), protein YukC
IMZ18_07100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMZ18_07105	COG3331	DNA recombination
IMZ18_07140	COG0071	Belongs to the small heat shock protein (HSP20) family
IMZ18_07145	COG2190	(PTS) system
IMZ18_07150	COG1111	helicase
IMZ18_07150	COG1205	dead DEAH box helicase
IMZ18_07155	COG3359	exonuclease
IMZ18_07170	COG4474	Belongs to the UPF0398 family
IMZ18_07185	COG0116	Belongs to the methyltransferase superfamily
IMZ18_07200	COG1199	ATP-dependent helicase activity
IMZ18_07205	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_07210	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IMZ18_07215	COG1609	Transcriptional regulator
IMZ18_07220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ18_07235	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IMZ18_07240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMZ18_07245	COG2233	PERMEase
IMZ18_07250	COG3424	synthase
IMZ18_07255	COG1755	Isoprenylcysteine carboxyl methyltransferase
IMZ18_07265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IMZ18_07280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMZ18_07290	COG0328	RNA-DNA hybrid ribonuclease activity
IMZ18_07295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IMZ18_07300	COG0328	RNA-DNA hybrid ribonuclease activity
IMZ18_07320	COG1278	Cold shock
IMZ18_07330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMZ18_07335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IMZ18_07340	COG0386	Belongs to the glutathione peroxidase family
IMZ18_07345	COG1418	mRNA catabolic process
IMZ18_07350	COG1413	lyase activity
IMZ18_07355	COG0129	dihydroxy-acid dehydratase activity
IMZ18_07365	COG2136	Putative SAM-dependent methyltransferase
IMZ18_07365	COG2521	methyltransferase
IMZ18_07375	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IMZ18_07380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMZ18_07385	COG0204	Acyl-transferase
IMZ18_07390	COG1272	protein, Hemolysin III
IMZ18_07395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IMZ18_07400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMZ18_07410	COG1999	signal sequence binding
IMZ18_07415	COG2755	lipolytic protein G-D-S-L family
IMZ18_07420	COG4698	Protein conserved in bacteria
IMZ18_07430	COG0534	Mate efflux family protein
IMZ18_07435	COG1846	Transcriptional regulator
IMZ18_07440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMZ18_07445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMZ18_07450	COG1086	Polysaccharide biosynthesis protein
IMZ18_07455	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
IMZ18_07460	COG4641	Protein conserved in bacteria
IMZ18_07475	COG0463	Glycosyl transferase, family 2
IMZ18_07480	COG0456	acetyltransferase
IMZ18_07500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMZ18_07505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMZ18_07510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IMZ18_07515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMZ18_07520	COG0456	acetyltransferase
IMZ18_07525	COG1509	lysine 2,3-aminomutase activity
IMZ18_07535	COG4479	Belongs to the UPF0346 family
IMZ18_07555	COG0671	phosphoesterase, PA-phosphatase related
IMZ18_07570	COG0813	purine-nucleoside phosphorylase activity
IMZ18_07575	COG1876	peptidase activity
IMZ18_07585	COG2226	methyltransferase
IMZ18_07590	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_07590	COG0793	Belongs to the peptidase S41A family
IMZ18_07595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ18_07610	COG0400	carboxylic ester hydrolase activity
IMZ18_07620	COG0778	Nitroreductase
IMZ18_07625	COG1733	regulation of RNA biosynthetic process
IMZ18_07630	COG1942	4-Oxalocrotonate Tautomerase
IMZ18_07650	COG2962	Rard protein
IMZ18_07660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMZ18_07665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IMZ18_07670	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_07675	COG0534	Mate efflux family protein
IMZ18_07680	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IMZ18_07685	COG1819	glycosyl
IMZ18_07690	COG0791	NLP P60 protein
IMZ18_07690	COG1388	LysM domain
IMZ18_07695	COG2032	superoxide dismutase activity
IMZ18_07700	COG0714	Associated with various cellular activities
IMZ18_07705	COG4548	von Willebrand factor, type A
IMZ18_07710	COG0567	Dehydrogenase, E1 component
IMZ18_07715	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMZ18_07720	COG0385	Bile acid
IMZ18_07725	COG0733	neurotransmitter:sodium symporter activity
IMZ18_07730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMZ18_07735	COG1657	PFAM Prenyltransferase squalene oxidase
IMZ18_07740	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_07765	COG0071	Belongs to the small heat shock protein (HSP20) family
IMZ18_07780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IMZ18_07785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IMZ18_07795	COG0514	ATP-dependent DNA helicase (RecQ)
IMZ18_07800	COG1388	LysM domain
IMZ18_07800	COG3584	3D domain protein
IMZ18_07805	COG2197	response regulator
IMZ18_07810	COG4585	Histidine kinase
IMZ18_07815	COG3239	Fatty acid desaturase
IMZ18_07820	COG1619	proteins homologs of microcin C7 resistance protein MccF
IMZ18_07835	COG2322	membrane
IMZ18_07840	COG0741	lytic transglycosylase activity
IMZ18_07845	COG0640	Transcriptional regulator
IMZ18_07855	COG2378	regulation of single-species biofilm formation
IMZ18_07860	COG3708	Transcriptional regulator
IMZ18_07865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ18_07870	COG1309	transcriptional regulator
IMZ18_07875	COG0456	acetyltransferase
IMZ18_07880	COG0662	Cupin 2, conserved barrel domain protein
IMZ18_07880	COG2207	Transcriptional regulator
IMZ18_07885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ18_07890	COG1231	oxidoreductase activity
IMZ18_07895	COG4282	regulation of fungal-type cell wall biogenesis
IMZ18_07900	COG5444	nuclease activity
IMZ18_07920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_07950	COG3328	transposase activity
IMZ18_07955	COG2211	Major facilitator Superfamily
IMZ18_07960	COG2226	methyltransferase
IMZ18_07965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMZ18_08020	COG3328	transposase activity
IMZ18_08050	COG3328	transposase activity
IMZ18_08055	COG2814	Major facilitator Superfamily
IMZ18_08065	COG1131	(ABC) transporter
IMZ18_08080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_08090	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IMZ18_08095	COG0300	oxidoreductase activity
IMZ18_08125	COG0583	DNA-binding transcription factor activity
IMZ18_08130	COG0069	glutamate synthase activity
IMZ18_08130	COG0067	glutamate synthase
IMZ18_08130	COG0070	glutamate synthase
IMZ18_08135	COG0493	'glutamate synthase
IMZ18_08140	COG0604	alcohol dehydrogenase
IMZ18_08145	COG0583	DNA-binding transcription factor activity
IMZ18_08150	COG0405	Gamma-glutamyltransferase
IMZ18_08155	COG0166	Belongs to the GPI family
IMZ18_08160	COG0582	viral genome integration into host DNA
IMZ18_08180	COG0534	Mate efflux family protein
IMZ18_08185	COG2017	converts alpha-aldose to the beta-anomer
IMZ18_08190	COG2027	D-alanyl-D-alanine carboxypeptidase
IMZ18_08210	COG1649	PFAM Uncharacterised BCR, COG1649
IMZ18_08220	COG1960	acyl-CoA dehydrogenase activity
IMZ18_08230	COG0439	Biotin carboxylase
IMZ18_08235	COG0511	ligase activity, forming carbon-carbon bonds
IMZ18_08240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IMZ18_08245	COG1024	Enoyl-CoA hydratase
IMZ18_08250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IMZ18_08255	COG2404	hydrolase activity, acting on ester bonds
IMZ18_08265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMZ18_08270	COG2246	polysaccharide biosynthetic process
IMZ18_08290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IMZ18_08295	COG1115	amino acid carrier protein
IMZ18_08305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMZ18_08315	COG1832	CoA-binding protein
IMZ18_08320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IMZ18_08325	COG4841	protein insertion into membrane
IMZ18_08340	COG0824	Thioesterase
IMZ18_08360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_08365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IMZ18_08380	COG0071	Belongs to the small heat shock protein (HSP20) family
IMZ18_08390	COG4846	Membrane protein involved in cytochrome C biogenesis
IMZ18_08395	COG2201	protein-glutamate methylesterase activity
IMZ18_08400	COG0785	Cytochrome C biogenesis protein
IMZ18_08410	COG3763	UPF0154 protein
IMZ18_08420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IMZ18_08425	COG4224	UPF0291 protein
IMZ18_08430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMZ18_08435	COG1388	LysM domain
IMZ18_08440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMZ18_08445	COG0346	lactoylglutathione lyase activity
IMZ18_08455	COG4195	phage-related replication protein
IMZ18_08500	COG3832	glyoxalase III activity
IMZ18_08515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMZ18_08560	COG0756	dUTP diphosphatase activity
IMZ18_08575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMZ18_08580	COG2814	Major facilitator Superfamily
IMZ18_08585	COG1525	nuclease
IMZ18_08590	COG3328	transposase activity
IMZ18_08600	COG1070	Carbohydrate kinase
IMZ18_08605	COG2115	Belongs to the xylose isomerase family
IMZ18_08610	COG1940	carbohydrate kinase activity
IMZ18_08615	COG3507	Belongs to the glycosyl hydrolase 43 family
IMZ18_08630	COG2211	Major facilitator Superfamily
IMZ18_08635	COG0135	phosphoribosylanthranilate isomerase activity
IMZ18_08660	COG3655	Transcriptional regulator
IMZ18_08675	COG3328	transposase activity
IMZ18_08695	COG4282	regulation of fungal-type cell wall biogenesis
IMZ18_08730	COG5444	nuclease activity
IMZ18_08740	COG1388	LysM domain
IMZ18_08740	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_08740	COG5632	N-Acetylmuramoyl-L-alanine amidase
IMZ18_08785	COG5412	phage tail tape measure protein
IMZ18_08785	COG3953	SLT domain
IMZ18_08930	COG3645	SOS response
IMZ18_08930	COG3646	Phage regulatory protein
IMZ18_08950	COG4974	Belongs to the 'phage' integrase family
IMZ18_08955	COG0174	glutamine synthetase
IMZ18_08960	COG0789	Transcriptional regulator
IMZ18_08965	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IMZ18_08970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMZ18_08975	COG0464	growth
IMZ18_08980	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMZ18_08985	COG4112	unkown
IMZ18_08990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMZ18_08995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMZ18_09000	COG1780	Probably involved in ribonucleotide reductase function
IMZ18_09015	COG1923	regulation of RNA biosynthetic process
IMZ18_09020	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMZ18_09035	COG2076	Multidrug Resistance protein
IMZ18_09040	COG2076	Multidrug Resistance protein
IMZ18_09045	COG1764	response to oxidative stress
IMZ18_09050	COG4195	phage-related replication protein
IMZ18_09060	COG1404	Belongs to the peptidase S8 family
IMZ18_09065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ18_09075	COG3226	Transcriptional regulator
IMZ18_09090	COG3328	transposase activity
IMZ18_09180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMZ18_09185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMZ18_09195	COG4550	Control of competence regulator ComK, YlbF/YmcA
IMZ18_09200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IMZ18_09205	COG0156	8-amino-7-oxononanoate synthase activity
IMZ18_09210	COG1063	alcohol dehydrogenase
IMZ18_09215	COG2359	stage V sporulation protein S
IMZ18_09220	COG1692	metallophosphoesterase
IMZ18_09225	COG1418	mRNA catabolic process
IMZ18_09230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMZ18_09235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMZ18_09245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMZ18_09250	COG1426	Protein conserved in bacteria
IMZ18_09265	COG0300	oxidoreductase activity
IMZ18_09270	COG0612	Peptidase, M16
IMZ18_09275	COG0612	Peptidase, M16
IMZ18_09280	COG2814	Major facilitator Superfamily
IMZ18_09285	COG2188	Transcriptional regulator
IMZ18_09290	COG4980	gas vesicle protein
IMZ18_09290	COG1674	ftsk spoiiie
IMZ18_09300	COG0740	serine-type endopeptidase activity
IMZ18_09305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMZ18_09310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMZ18_09315	COG0527	aspartate kinase activity
IMZ18_09320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMZ18_09325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMZ18_09330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMZ18_09335	COG1873	PFAM PRC-barrel domain
IMZ18_09340	COG0612	Peptidase, M16
IMZ18_09345	COG0726	polysaccharide deacetylase
IMZ18_09350	COG1185	polyribonucleotide nucleotidyltransferase activity
IMZ18_09355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMZ18_09360	COG0196	riboflavin kinase activity
IMZ18_09365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMZ18_09370	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMZ18_09375	COG1550	Protein conserved in bacteria
IMZ18_09380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IMZ18_09385	COG1358	cellular component organization or biogenesis
IMZ18_09390	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IMZ18_09395	COG0195	Participates in both transcription termination and antitermination
IMZ18_09400	COG0779	Required for maturation of 30S ribosomal subunits
IMZ18_09410	COG0442	prolyl-tRNA aminoacylation
IMZ18_09415	COG0750	zinc metalloprotease
IMZ18_09420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IMZ18_09425	COG4589	Belongs to the CDS family
IMZ18_09430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMZ18_09435	COG0233	cytoplasmic translational termination
IMZ18_09440	COG0528	UMP kinase activity
IMZ18_09445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMZ18_09450	COG0052	Belongs to the universal ribosomal protein uS2 family
IMZ18_09460	COG1191	sigma factor activity
IMZ18_09465	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IMZ18_09475	COG0835	chemotaxis
IMZ18_09480	COG0643	Histidine kinase
IMZ18_09480	COG2198	Histidine kinase
IMZ18_09485	COG2201	protein-glutamate methylesterase activity
IMZ18_09490	COG0455	bacterial-type flagellum organization
IMZ18_09495	COG1419	protein localization to endoplasmic reticulum
IMZ18_09500	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMZ18_09505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IMZ18_09510	COG1684	flagellar biosynthetic protein fliR
IMZ18_09515	COG1987	bacterial-type flagellum assembly
IMZ18_09520	COG1338	Plays a role in the flagellum-specific transport system
IMZ18_09525	COG3190	flagellar
IMZ18_09530	COG2201	protein-glutamate methylesterase activity
IMZ18_09535	COG1776	CheC inhibitor of MCP methylation
IMZ18_09535	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMZ18_09540	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMZ18_09545	COG1580	Controls the rotational direction of flagella during chemotaxis
IMZ18_09550	COG1582	Flagellar protein (FlbD)
IMZ18_09555	COG4786	Flagellar basal body rod
IMZ18_09560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IMZ18_09565	COG3144	bacterial-type flagellum assembly
IMZ18_09570	COG3334	PFAM MgtE intracellular
IMZ18_09575	COG2882	bacterial-type flagellum organization
IMZ18_09580	COG1157	protein secretion by the type III secretion system
IMZ18_09585	COG1317	bacterial-type flagellum organization
IMZ18_09590	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IMZ18_09600	COG1677	Flagellar hook-basal body complex protein FliE
IMZ18_09605	COG1558	bacterial-type flagellum-dependent cell motility
IMZ18_09610	COG1815	bacterial-type flagellum-dependent cell motility
IMZ18_09615	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IMZ18_09620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IMZ18_09625	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IMZ18_09630	COG4974	Belongs to the 'phage' integrase family
IMZ18_09635	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IMZ18_09640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMZ18_09645	COG0758	DNA mediated transformation
IMZ18_09650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IMZ18_09655	COG0045	succinate-CoA ligase (ADP-forming) activity
IMZ18_09660	COG2257	FlhB HrpN YscU SpaS Family
IMZ18_09670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMZ18_09675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMZ18_09680	COG0335	large ribosomal subunit rRNA binding
IMZ18_09685	COG0336	Belongs to the RNA methyltransferase TrmD family
IMZ18_09690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IMZ18_09700	COG1837	Belongs to the UPF0109 family
IMZ18_09705	COG0228	four-way junction DNA binding
IMZ18_09710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMZ18_09715	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMZ18_09725	COG0552	protein localization to endoplasmic reticulum
IMZ18_09730	COG1196	nuclear chromosome segregation
IMZ18_09735	COG0571	ribonuclease III activity
IMZ18_09745	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_09750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMZ18_09755	COG0416	fatty acid biosynthetic process
IMZ18_09760	COG2050	protein possibly involved in aromatic compounds catabolism
IMZ18_09760	COG1349	DNA-binding transcription factor activity
IMZ18_09765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMZ18_09770	COG1760	l-serine dehydratase
IMZ18_09775	COG1760	l-serine dehydratase
IMZ18_09780	COG1461	Dihydroxyacetone kinase
IMZ18_09785	COG1302	Protein conserved in bacteria
IMZ18_09790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMZ18_09800	COG1564	THIamine pyrophosphokinase
IMZ18_09805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMZ18_09810	COG1162	GTPase activity
IMZ18_09820	COG0631	protein serine/threonine phosphatase activity
IMZ18_09825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IMZ18_09830	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMZ18_09830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMZ18_09835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMZ18_09840	COG0242	peptide deformylase activity
IMZ18_09845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMZ18_09850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMZ18_09855	COG1758	RNA polymerase activity
IMZ18_09860	COG0194	GDP metabolic process
IMZ18_09870	COG1561	YicC-like family, N-terminal region
IMZ18_09885	COG1648	precorrin-2 dehydrogenase activity
IMZ18_09890	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
IMZ18_09895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IMZ18_09900	COG0529	Catalyzes the synthesis of activated sulfate
IMZ18_09905	COG2046	Belongs to the sulfate adenylyltransferase family
IMZ18_09910	COG0306	phosphate transporter
IMZ18_09915	COG0175	sulfate reduction
IMZ18_09920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IMZ18_09925	COG0284	orotidine-5'-phosphate decarboxylase activity
IMZ18_09930	COG0167	dihydroorotate dehydrogenase activity
IMZ18_09935	COG0543	2 iron, 2 sulfur cluster binding
IMZ18_09940	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMZ18_09945	COG0505	Belongs to the CarA family
IMZ18_09950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMZ18_09955	COG0540	Belongs to the ATCase OTCase family
IMZ18_09960	COG2233	PERMEase
IMZ18_09965	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMZ18_09970	COG0564	pseudouridine synthase activity
IMZ18_09975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMZ18_09980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IMZ18_09985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMZ18_09990	COG3599	regulation of cell shape
IMZ18_09995	COG2302	S4 RNA-binding domain
IMZ18_10000	COG0762	integral membrane protein
IMZ18_10005	COG1799	cell septum assembly
IMZ18_10010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMZ18_10015	COG1496	oxidoreductase activity
IMZ18_10020	COG1873	PFAM PRC-barrel domain
IMZ18_10025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMZ18_10030	COG1119	ATPase activity
IMZ18_10035	COG1191	sigma factor activity
IMZ18_10040	COG1191	sigma factor activity
IMZ18_10050	COG4412	M6 family metalloprotease domain protein
IMZ18_10050	COG1404	Belongs to the peptidase S8 family
IMZ18_10055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IMZ18_10065	COG3856	small basic protein
IMZ18_10070	COG3879	Bacterial protein of unknown function (DUF881)
IMZ18_10075	COG3879	Bacterial protein of unknown function (DUF881)
IMZ18_10080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMZ18_10085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMZ18_10090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMZ18_10095	COG0772	Belongs to the SEDS family
IMZ18_10100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMZ18_10105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMZ18_10110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMZ18_10115	COG0768	penicillin binding
IMZ18_10120	COG0768	penicillin binding
IMZ18_10125	COG4839	cell division protein FtsL
IMZ18_10130	COG0275	rRNA processing
IMZ18_10135	COG2001	Belongs to the MraZ family
IMZ18_10140	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IMZ18_10145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMZ18_10150	COG0454	-acetyltransferase
IMZ18_10165	COG1399	metal-binding, possibly nucleic acid-binding protein
IMZ18_10175	COG1323	Belongs to the UPF0348 family
IMZ18_10180	COG3480	Lon protease (S16) C-terminal proteolytic domain
IMZ18_10185	COG1752	Esterase of the alpha-beta hydrolase superfamily
IMZ18_10190	COG3314	Sporulation integral membrane protein YlbJ
IMZ18_10195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMZ18_10200	COG0742	ribosomal rna small subunit methyltransferase
IMZ18_10205	COG4471	UPF0298 protein
IMZ18_10210	COG3679	Belongs to the UPF0342 family
IMZ18_10225	COG2340	Cysteine-rich secretory protein family
IMZ18_10230	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IMZ18_10240	COG3336	cytochrome c oxidase
IMZ18_10245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IMZ18_10250	COG1845	cytochrome c oxidase, subunit III
IMZ18_10260	COG2010	Cytochrome c
IMZ18_10260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMZ18_10265	COG0109	protoheme IX farnesyltransferase activity
IMZ18_10270	COG1612	heme a metabolic process
IMZ18_10275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMZ18_10280	COG0772	Belongs to the SEDS family
IMZ18_10285	COG4838	Belongs to the UPF0358 family
IMZ18_10290	COG2066	Belongs to the glutaminase family
IMZ18_10295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IMZ18_10300	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IMZ18_10310	COG4896	Protein conserved in bacteria
IMZ18_10320	COG1217	gtp-binding protein TYPA
IMZ18_10360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IMZ18_10375	COG0483	inositol monophosphate 1-phosphatase activity
IMZ18_10385	COG4493	Belongs to the UPF0637 family
IMZ18_10390	COG4476	Belongs to the UPF0223 family
IMZ18_10395	COG1982	Orn Lys Arg decarboxylase major
IMZ18_10405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_10410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ18_10415	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMZ18_10420	COG0022	dehydrogenase e1 component
IMZ18_10425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMZ18_10440	COG0242	peptide deformylase activity
IMZ18_10445	COG0561	phosphatase activity
IMZ18_10450	COG5503	Protein of unknown function (DUF1447)
IMZ18_10455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMZ18_10460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMZ18_10465	COG0569	domain protein
IMZ18_10470	COG2105	PFAM AIG2 family protein
IMZ18_10470	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IMZ18_10475	COG3852	Histidine kinase
IMZ18_10480	COG2002	toxin-antitoxin pair type II binding
IMZ18_10485	COG1077	Cell shape determining protein MreB Mrl
IMZ18_10495	COG2309	aminopeptidase activity
IMZ18_10500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IMZ18_10505	COG0488	(ABC) transporter
IMZ18_10515	COG0681	Belongs to the peptidase S26 family
IMZ18_10520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ18_10520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_10520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ18_10525	COG1105	Belongs to the carbohydrate kinase PfkB family
IMZ18_10530	COG1349	DNA-binding transcription factor activity
IMZ18_10535	COG0577	efflux transmembrane transporter activity
IMZ18_10540	COG1136	(ABC) transporter
IMZ18_10545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IMZ18_10555	COG1132	(ABC) transporter
IMZ18_10565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IMZ18_10570	COG0314	molybdopterin synthase activity
IMZ18_10575	COG1763	Mo-molybdopterin cofactor biosynthetic process
IMZ18_10580	COG0303	'Molybdopterin
IMZ18_10585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMZ18_10590	COG0746	molybdenum cofactor guanylyltransferase activity
IMZ18_10610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_10615	COG0450	alkyl hydroperoxide reductase
IMZ18_10620	COG0668	transmembrane transport
IMZ18_10630	COG1473	amidohydrolase
IMZ18_10635	COG2171	N-acyltransferase activity
IMZ18_10640	COG0716	FMN binding
IMZ18_10650	COG0716	FMN binding
IMZ18_10655	COG0583	DNA-binding transcription factor activity
IMZ18_10660	COG0517	IMP dehydrogenase activity
IMZ18_10670	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
IMZ18_10675	COG4703	Protein of unknown function (DUF1797)
IMZ18_10680	COG2200	EAL domain
IMZ18_10685	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_10695	COG1408	metallophosphoesterase
IMZ18_10700	COG1376	ErfK ybiS ycfS ynhG family protein
IMZ18_10705	COG2814	Major facilitator Superfamily
IMZ18_10715	COG0784	Response regulator, receiver
IMZ18_10715	COG0835	chemotaxis
IMZ18_10725	COG0436	Aminotransferase
IMZ18_10735	COG0768	penicillin binding
IMZ18_10740	COG2340	Cysteine-rich secretory protein family
IMZ18_10745	COG3328	transposase activity
IMZ18_10750	COG2084	Dehydrogenase
IMZ18_10755	COG0840	transmembrane signaling receptor activity
IMZ18_10760	COG0456	acetyltransferase
IMZ18_10765	COG1533	DNA photolyase activity
IMZ18_10775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IMZ18_10780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_10785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_10785	COG1263	PTS System
IMZ18_10785	COG2190	(PTS) system
IMZ18_10790	COG3711	transcriptional antiterminator
IMZ18_10795	COG1609	Transcriptional regulator
IMZ18_10800	COG0006	proline dipeptidase activity
IMZ18_10810	COG2217	Heavy metal translocating P-type atpase
IMZ18_10815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_10820	COG2244	polysaccharide biosynthetic process
IMZ18_10825	COG3773	Cell wall hydrolase
IMZ18_10835	COG4873	Protein conserved in bacteria
IMZ18_10845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IMZ18_10850	COG0602	queuosine metabolic process
IMZ18_10855	COG0720	synthase
IMZ18_10860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IMZ18_10865	COG3949	Membrane
IMZ18_10870	COG0542	response to heat
IMZ18_10875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IMZ18_10880	COG1360	Flagellar Motor Protein
IMZ18_10885	COG1846	Transcriptional regulator
IMZ18_10890	COG3852	Histidine kinase
IMZ18_10910	COG3339	Conserved Protein
IMZ18_10915	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IMZ18_10920	COG0235	Class ii aldolase
IMZ18_10925	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IMZ18_10930	COG1850	ribulose-bisphosphate carboxylase activity
IMZ18_10935	COG0436	Aminotransferase
IMZ18_10940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMZ18_10945	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IMZ18_10950	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IMZ18_10960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMZ18_10965	COG5002	protein histidine kinase activity
IMZ18_10970	COG3594	Acyltransferase
IMZ18_10985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMZ18_10990	COG0501	Belongs to the peptidase M48B family
IMZ18_11010	COG1191	sigma factor activity
IMZ18_11015	COG0861	Integral membrane protein TerC family
IMZ18_11020	COG0586	Pfam SNARE associated Golgi protein
IMZ18_11025	COG5001	Diguanylate cyclase
IMZ18_11025	COG3300	MHYT domain
IMZ18_11030	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IMZ18_11035	COG1793	dna ligase
IMZ18_11035	COG3285	dna ligase
IMZ18_11040	COG0463	Glycosyl transferase, family 2
IMZ18_11050	COG1408	metallophosphoesterase
IMZ18_11055	COG0726	polysaccharide deacetylase
IMZ18_11060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMZ18_11065	COG1846	Transcriptional regulator
IMZ18_11080	COG0789	Transcriptional regulator
IMZ18_11085	COG2239	Acts as a magnesium transporter
IMZ18_11095	COG3212	peptidase
IMZ18_11100	COG3212	peptidase
IMZ18_11105	COG5002	protein histidine kinase activity
IMZ18_11105	COG3850	Histidine kinase
IMZ18_11110	COG0745	RESPONSE REGULATOR receiver
IMZ18_11120	COG4721	ABC-type cobalt transport system, permease component
IMZ18_11125	COG1122	ATPase activity
IMZ18_11130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMZ18_11135	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_11140	COG1404	Belongs to the peptidase S8 family
IMZ18_11145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMZ18_11150	COG0590	tRNA wobble adenosine to inosine editing
IMZ18_11160	COG1764	response to oxidative stress
IMZ18_11165	COG1846	Transcriptional regulator
IMZ18_11170	COG1764	response to oxidative stress
IMZ18_11175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMZ18_11180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMZ18_11185	COG0788	formyltetrahydrofolate deformylase activity
IMZ18_11190	COG2076	Multidrug Resistance protein
IMZ18_11195	COG2076	Multidrug Resistance protein
IMZ18_11200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_11205	COG2318	DinB family
IMZ18_11210	COG2323	membrane
IMZ18_11220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IMZ18_11220	COG1017	nitric oxide dioxygenase activity
IMZ18_11225	COG1607	acyl-coa hydrolase
IMZ18_11235	COG2706	6-phosphogluconolactonase activity
IMZ18_11240	COG4608	Belongs to the ABC transporter superfamily
IMZ18_11245	COG0791	NLP P60 protein
IMZ18_11250	COG4948	Mandelate Racemase Muconate Lactonizing
IMZ18_11255	COG1619	proteins homologs of microcin C7 resistance protein MccF
IMZ18_11260	COG4166	transmembrane transport
IMZ18_11265	COG0444	Belongs to the ABC transporter superfamily
IMZ18_11270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMZ18_11275	COG0601	transmembrane transport
IMZ18_11280	COG2362	D-Aminopeptidase
IMZ18_11285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMZ18_11290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMZ18_11295	COG0463	Glycosyl transferase, family 2
IMZ18_11300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IMZ18_11305	COG0346	lactoylglutathione lyase activity
IMZ18_11310	COG0531	amino acid
IMZ18_11315	COG1392	Phosphate transport regulator
IMZ18_11320	COG0306	phosphate transporter
IMZ18_11340	COG5632	N-Acetylmuramoyl-L-alanine amidase
IMZ18_11340	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_11380	COG3778	Protein conserved in bacteria
IMZ18_11385	COG3299	homolog of phage Mu protein gp47
IMZ18_11390	COG3628	GPW Gp25 family protein
IMZ18_11400	COG4193	domain, Protein
IMZ18_11405	COG1652	LysM domain
IMZ18_11460	COG4653	Phage capsid family
IMZ18_11465	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IMZ18_11470	COG5518	Phage portal protein
IMZ18_11475	COG1783	phage Terminase large subunit
IMZ18_11480	COG3728	DNA packaging
IMZ18_11480	COG5484	DNA packaging
IMZ18_11485	COG1595	DNA-templated transcription, initiation
IMZ18_11505	COG1484	DNA-dependent DNA replication
IMZ18_11510	COG1522	sequence-specific DNA binding
IMZ18_11520	COG1396	sequence-specific DNA binding
IMZ18_11525	COG2856	Zn peptidase
IMZ18_11530	COG3546	catalase activity
IMZ18_11535	COG4195	phage-related replication protein
IMZ18_11545	COG5632	N-Acetylmuramoyl-L-alanine amidase
IMZ18_11545	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_11545	COG1388	LysM domain
IMZ18_11560	COG0457	Tetratricopeptide repeat
IMZ18_11580	COG2318	DinB family
IMZ18_11585	COG0730	response to heat
IMZ18_11590	COG2721	sulfolactate sulfo-lyase activity
IMZ18_11595	COG0246	Mannitol dehydrogenase
IMZ18_11600	COG1609	Transcriptional regulator
IMZ18_11605	COG2271	Major facilitator Superfamily
IMZ18_11610	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_11615	COG1312	Catalyzes the dehydration of D-mannonate
IMZ18_11620	COG1063	alcohol dehydrogenase
IMZ18_11625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IMZ18_11630	COG2211	Major facilitator Superfamily
IMZ18_11640	COG1252	NADH dehydrogenase
IMZ18_11655	COG0697	spore germination
IMZ18_11660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMZ18_11665	COG0390	transport system, permease component
IMZ18_11670	COG1587	Uroporphyrinogen-III synthase
IMZ18_11680	COG1819	glycosyl
IMZ18_11685	COG2124	cytochrome p450
IMZ18_11695	COG1051	belongs to the nudix hydrolase family
IMZ18_11705	COG2427	Protein of unknown function (DUF1641)
IMZ18_11720	COG2205	protein histidine kinase activity
IMZ18_11725	COG5504	Zn-dependent protease
IMZ18_11740	COG0726	polysaccharide deacetylase
IMZ18_11750	COG0109	protoheme IX farnesyltransferase activity
IMZ18_11765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMZ18_11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_11790	COG1482	cell wall glycoprotein biosynthetic process
IMZ18_11795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_11795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ18_11795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMZ18_11800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_11800	COG3711	transcriptional antiterminator
IMZ18_11810	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IMZ18_11860	COG3328	transposase activity
IMZ18_11870	COG5444	nuclease activity
IMZ18_11875	COG0457	Tetratricopeptide repeat
IMZ18_11950	COG1396	sequence-specific DNA binding
IMZ18_11980	COG5505	Protein of unknown function (DUF819)
IMZ18_11985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_11990	COG0626	cystathionine gamma-synthase activity
IMZ18_11995	COG0626	cystathionine gamma-synthase activity
IMZ18_12000	COG2382	esterase
IMZ18_12005	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IMZ18_12010	COG2153	protein acetylation
IMZ18_12020	COG0210	DNA helicase
IMZ18_12075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMZ18_12080	COG0351	phosphomethylpyrimidine kinase
IMZ18_12085	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMZ18_12090	COG2022	thiamine diphosphate biosynthetic process
IMZ18_12095	COG2104	thiamine diphosphate biosynthetic process
IMZ18_12100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMZ18_12105	COG0352	thiamine-phosphate diphosphorylase activity
IMZ18_12110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IMZ18_12115	COG0569	domain protein
IMZ18_12115	COG0475	glutathione-regulated potassium exporter activity
IMZ18_12120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IMZ18_12125	COG0564	pseudouridine synthase activity
IMZ18_12130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IMZ18_12135	COG2357	RelA SpoT domain protein
IMZ18_12145	COG4116	CYTH
IMZ18_12150	COG0741	lytic transglycosylase activity
IMZ18_12155	COG2346	COG2346, Truncated hemoglobins
IMZ18_12160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMZ18_12175	COG4469	Competence protein
IMZ18_12185	COG4862	establishment of competence for transformation
IMZ18_12195	COG0861	Integral membrane protein TerC family
IMZ18_12200	COG1393	Belongs to the ArsC family
IMZ18_12205	COG0456	acetyltransferase
IMZ18_12210	COG2814	Major facilitator Superfamily
IMZ18_12215	COG4608	Belongs to the ABC transporter superfamily
IMZ18_12220	COG0444	Belongs to the ABC transporter superfamily
IMZ18_12225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMZ18_12230	COG0601	transmembrane transport
IMZ18_12235	COG4166	transmembrane transport
IMZ18_12240	COG0180	Tryptophanyl-tRNA synthetase
IMZ18_12250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMZ18_12255	COG0601	transmembrane transport
IMZ18_12265	COG4608	Belongs to the ABC transporter superfamily
IMZ18_12270	COG0444	Belongs to the ABC transporter superfamily
IMZ18_12275	COG5504	Zn-dependent protease
IMZ18_12280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMZ18_12285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMZ18_12300	COG1744	ABC transporter substrate-binding protein PnrA-like
IMZ18_12310	COG2267	carboxylic ester hydrolase activity
IMZ18_12330	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMZ18_12335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMZ18_12340	COG0505	Belongs to the CarA family
IMZ18_12345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMZ18_12355	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMZ18_12360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMZ18_12380	COG2151	metal-sulfur cluster biosynthetic enzyme
IMZ18_12385	COG1073	alpha beta
IMZ18_12390	COG0561	phosphatase activity
IMZ18_12410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMZ18_12415	COG1307	EDD domain protein, DegV family
IMZ18_12430	COG2996	Protein conserved in bacteria
IMZ18_12435	COG1666	GTP binding
IMZ18_12440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IMZ18_12440	COG0646	methionine synthase
IMZ18_12445	COG2153	protein acetylation
IMZ18_12455	COG2267	carboxylic ester hydrolase activity
IMZ18_12460	COG1357	PFAM Pentapeptide repeats (8 copies)
IMZ18_12465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ18_12470	COG1279	arginine transmembrane transporter activity
IMZ18_12475	COG2318	DinB family
IMZ18_12480	COG0673	inositol 2-dehydrogenase activity
IMZ18_12485	COG1609	Transcriptional regulator
IMZ18_12490	COG2207	Transcriptional regulator
IMZ18_12490	COG1917	Cupin 2, conserved barrel domain protein
IMZ18_12495	COG0534	Mate efflux family protein
IMZ18_12500	COG1562	ergosterol biosynthetic process
IMZ18_12505	COG0367	asparagine synthase
IMZ18_12515	COG1404	Belongs to the peptidase S8 family
IMZ18_12525	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMZ18_12530	COG5337	Spore coat protein CotH
IMZ18_12570	COG1403	HNH endonuclease
IMZ18_12575	COG0419	ATPase involved in DNA repair
IMZ18_12580	COG0420	3'-5' exonuclease activity
IMZ18_12585	COG1074	ATP-dependent DNA helicase activity
IMZ18_12590	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IMZ18_12595	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IMZ18_12610	COG4533	DNA binding
IMZ18_12615	COG0477	Major facilitator Superfamily
IMZ18_12615	COG2814	Major facilitator Superfamily
IMZ18_12620	COG3180	Ammonia monooxygenase
IMZ18_12625	COG1609	Transcriptional regulator
IMZ18_12630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMZ18_12635	COG0561	phosphatase activity
IMZ18_12640	COG0673	inositol 2-dehydrogenase activity
IMZ18_12645	COG0738	Major facilitator superfamily
IMZ18_12660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMZ18_12665	COG0681	Belongs to the peptidase S26 family
IMZ18_12670	COG0398	Pfam SNARE associated Golgi protein
IMZ18_12685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ18_12695	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_12700	COG4903	ComK protein
IMZ18_12710	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_12720	COG0840	transmembrane signaling receptor activity
IMZ18_12725	COG1268	BioY protein
IMZ18_12730	COG0318	PFAM AMP-dependent synthetase and ligase
IMZ18_12735	COG0183	Belongs to the thiolase family
IMZ18_12740	COG0406	alpha-ribazole phosphatase activity
IMZ18_12745	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IMZ18_12750	COG0604	alcohol dehydrogenase
IMZ18_12755	COG0456	acetyltransferase
IMZ18_12765	COG0501	Belongs to the peptidase M48B family
IMZ18_12775	COG0318	PFAM AMP-dependent synthetase and ligase
IMZ18_12780	COG0702	epimerase
IMZ18_12785	COG0095	Lipoate-protein ligase
IMZ18_12790	COG1234	tRNA 3'-trailer cleavage
IMZ18_12805	COG4405	Protein conserved in bacteria
IMZ18_12810	COG1363	Peptidase, m42
IMZ18_12820	COG4377	Putative membrane peptidase family (DUF2324)
IMZ18_12825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IMZ18_12830	COG1511	domain protein
IMZ18_12835	COG1309	transcriptional regulator
IMZ18_12840	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IMZ18_12845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IMZ18_12850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IMZ18_12855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMZ18_12860	COG2329	Antibiotic biosynthesis monooxygenase
IMZ18_12870	COG3069	C4-dicarboxylate transmembrane transporter activity
IMZ18_12875	COG1473	amidohydrolase
IMZ18_12885	COG4473	ABC transporter
IMZ18_12890	COG1131	(ABC) transporter
IMZ18_12895	COG0537	adenosine 5'-monophosphoramidase activity
IMZ18_12900	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMZ18_12915	COG4980	gas vesicle protein
IMZ18_12920	COG1846	Transcriptional regulator
IMZ18_12950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMZ18_12960	COG3481	metal-dependent phosphohydrolase, HD sub domain
IMZ18_12965	COG4717	serine-type aminopeptidase activity
IMZ18_12970	COG0420	3'-5' exonuclease activity
IMZ18_12975	COG1668	transmembrane transport
IMZ18_12980	COG4152	abc transporter atp-binding protein
IMZ18_12990	COG1024	Enoyl-CoA hydratase
IMZ18_13005	COG0475	glutathione-regulated potassium exporter activity
IMZ18_13010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IMZ18_13015	COG0561	phosphatase activity
IMZ18_13025	COG3679	Belongs to the UPF0342 family
IMZ18_13030	COG4399	Belongs to the UPF0754 family
IMZ18_13040	COG0189	ligase activity
IMZ18_13065	COG0702	epimerase
IMZ18_13070	COG1132	(ABC) transporter
IMZ18_13075	COG1132	(ABC) transporter
IMZ18_13085	COG0589	response to stress
IMZ18_13090	COG1757	Na H antiporter
IMZ18_13095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMZ18_13100	COG0726	polysaccharide deacetylase
IMZ18_13105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IMZ18_13110	COG0668	transmembrane transport
IMZ18_13120	COG0584	glycerophosphoryl diester phosphodiesterase
IMZ18_13130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IMZ18_13135	COG1253	flavin adenine dinucleotide binding
IMZ18_13145	COG0789	Transcriptional regulator
IMZ18_13150	COG1253	flavin adenine dinucleotide binding
IMZ18_13155	COG0204	Acyl-transferase
IMZ18_13160	COG0667	Aldo Keto reductase
IMZ18_13165	COG1595	DNA-templated transcription, initiation
IMZ18_13180	COG0456	acetyltransferase
IMZ18_13185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ18_13190	COG0733	neurotransmitter:sodium symporter activity
IMZ18_13195	COG0531	amino acid
IMZ18_13200	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_13205	COG0372	Belongs to the citrate synthase family
IMZ18_13210	COG0583	DNA-binding transcription factor activity
IMZ18_13215	COG0791	NLP P60 protein
IMZ18_13215	COG1388	LysM domain
IMZ18_13220	COG1785	Belongs to the alkaline phosphatase family
IMZ18_13225	COG2719	SpoVR family
IMZ18_13230	COG0668	transmembrane transport
IMZ18_13235	COG1959	2 iron, 2 sulfur cluster binding
IMZ18_13240	COG0791	NLP P60 protein
IMZ18_13240	COG1388	LysM domain
IMZ18_13255	COG0431	NADPH-dependent FMN reductase
IMZ18_13260	COG2197	response regulator
IMZ18_13265	COG2203	Gaf domain
IMZ18_13265	COG4585	Histidine kinase
IMZ18_13270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMZ18_13275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMZ18_13280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IMZ18_13285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMZ18_13290	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IMZ18_13295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IMZ18_13300	COG3153	acetyltransferase
IMZ18_13300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IMZ18_13305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMZ18_13310	COG0517	IMP dehydrogenase activity
IMZ18_13320	COG0564	pseudouridine synthase activity
IMZ18_13325	COG3764	Sortase (surface protein transpeptidase)
IMZ18_13330	COG1525	nuclease
IMZ18_13330	COG4085	toxin activity
IMZ18_13330	COG0737	Belongs to the 5'-nucleotidase family
IMZ18_13355	COG0457	Tetratricopeptide repeat
IMZ18_13375	COG0791	NLP P60 protein
IMZ18_13375	COG0741	lytic transglycosylase activity
IMZ18_13380	COG5644	endopeptidase inhibitor activity
IMZ18_13435	COG2946	Replication initiation factor
IMZ18_13440	COG0582	viral genome integration into host DNA
IMZ18_13465	COG5444	nuclease activity
IMZ18_13470	COG1823	symporter activity
IMZ18_13475	COG3706	GGDEF domain
IMZ18_13480	COG1464	Belongs to the NlpA lipoprotein family
IMZ18_13485	COG1278	Cold shock
IMZ18_13490	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IMZ18_13495	COG1131	(ABC) transporter
IMZ18_13500	COG1131	(ABC) transporter
IMZ18_13505	COG1725	Transcriptional regulator
IMZ18_13525	COG0655	NAD(P)H dehydrogenase (quinone) activity
IMZ18_13530	COG2814	Major facilitator Superfamily
IMZ18_13535	COG1566	PFAM secretion protein HlyD family protein
IMZ18_13540	COG1846	Transcriptional regulator
IMZ18_13545	COG2718	Belongs to the UPF0229 family
IMZ18_13550	COG2766	serine protein kinase
IMZ18_13555	COG1664	Polymer-forming cytoskeletal
IMZ18_13560	COG1664	Polymer-forming cytoskeletal
IMZ18_13565	COG0789	Transcriptional regulator
IMZ18_13570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMZ18_13580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IMZ18_13585	COG3382	B3 4 domain protein
IMZ18_13595	COG1476	TRANSCRIPTIONal
IMZ18_13605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMZ18_13615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMZ18_13620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IMZ18_13625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMZ18_13630	COG1116	anion transmembrane transporter activity
IMZ18_13635	COG0753	catalase activity
IMZ18_13650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IMZ18_13655	COG3340	Belongs to the peptidase S51 family
IMZ18_13660	COG5577	PFAM Coat F domain
IMZ18_13670	COG4326	sporulation control protein
IMZ18_13780	COG0735	belongs to the Fur family
IMZ18_13785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IMZ18_13790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IMZ18_13795	COG4129	membrane
IMZ18_13800	COG1132	(ABC) transporter
IMZ18_13805	COG3557	Belongs to the UPF0374 family
IMZ18_13820	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_13830	COG1194	a g-specific adenine glycosylase
IMZ18_13835	COG1988	membrane-bound metal-dependent
IMZ18_13840	COG4485	Bacterial membrane protein, YfhO
IMZ18_13845	COG0463	Glycosyl transferase, family 2
IMZ18_13850	COG0596	Alpha beta hydrolase
IMZ18_13855	COG5658	integral membrane protein
IMZ18_13860	COG3103	Sh3 type 3 domain protein
IMZ18_13875	COG2814	Major facilitator Superfamily
IMZ18_13885	COG2137	regulation of response to DNA damage stimulus
IMZ18_13890	COG1090	epimerase
IMZ18_13905	COG0778	Nitroreductase
IMZ18_13910	COG0384	phenazine biosynthesis protein PhzF
IMZ18_13915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ18_13920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ18_13925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ18_13930	COG0392	lysyltransferase activity
IMZ18_13930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IMZ18_13935	COG1846	Transcriptional regulator
IMZ18_13945	COG2318	DinB family
IMZ18_13950	COG2814	Major facilitator Superfamily
IMZ18_13955	COG1309	transcriptional regulator
IMZ18_13960	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IMZ18_13965	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IMZ18_13970	COG1695	Transcriptional regulator
IMZ18_13975	COG0842	Transport permease protein
IMZ18_13980	COG0842	Transport permease protein
IMZ18_13980	COG1511	domain protein
IMZ18_13985	COG1131	(ABC) transporter
IMZ18_13990	COG2197	response regulator
IMZ18_13995	COG4585	Histidine kinase
IMZ18_14005	COG1082	Xylose isomerase domain protein TIM barrel
IMZ18_14010	COG2814	Major facilitator Superfamily
IMZ18_14015	COG1917	Cupin 2, conserved barrel domain protein
IMZ18_14015	COG4977	sequence-specific DNA binding
IMZ18_14020	COG2514	catechol 2,3-dioxygenase activity
IMZ18_14025	COG2259	Doxx family
IMZ18_14030	COG1132	(ABC) transporter
IMZ18_14035	COG1132	(ABC) transporter
IMZ18_14040	COG5434	Belongs to the glycosyl hydrolase 28 family
IMZ18_14045	COG1263	PTS System
IMZ18_14045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_14050	COG1737	Transcriptional regulator
IMZ18_14055	COG1486	melibiose metabolic process
IMZ18_14065	COG4842	Belongs to the WXG100 family
IMZ18_14090	COG1742	UPF0060 membrane protein
IMZ18_14100	COG3284	Transcriptional regulator
IMZ18_14105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMZ18_14110	COG0508	dehydrogenase complex catalyzes the overall conversion of
IMZ18_14115	COG0022	dehydrogenase e1 component
IMZ18_14120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IMZ18_14130	COG4637	Psort location Cytoplasmic, score
IMZ18_14135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMZ18_14145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMZ18_14150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IMZ18_14155	COG0598	Magnesium transport protein CorA
IMZ18_14160	COG2084	Dehydrogenase
IMZ18_14165	COG0726	polysaccharide deacetylase
IMZ18_14175	COG0535	radical SAM domain protein
IMZ18_14180	COG0668	transmembrane transport
IMZ18_14190	COG0387	Pfam Sodium calcium exchanger
IMZ18_14195	COG0477	Major facilitator Superfamily
IMZ18_14200	COG1295	ribonuclease BN
IMZ18_14205	COG4980	gas vesicle protein
IMZ18_14210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMZ18_14215	COG4840	Belongs to the UPF0435 family
IMZ18_14220	COG2814	Major facilitator Superfamily
IMZ18_14230	COG0693	protein deglycase activity
IMZ18_14235	COG0737	Belongs to the 5'-nucleotidase family
IMZ18_14250	COG0778	Nitroreductase
IMZ18_14255	COG2188	Transcriptional regulator
IMZ18_14260	COG0366	Alpha amylase catalytic
IMZ18_14265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_14265	COG1263	PTS System
IMZ18_14270	COG0697	spore germination
IMZ18_14285	COG1115	amino acid carrier protein
IMZ18_14300	COG1368	sulfuric ester hydrolase activity
IMZ18_14305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_14305	COG1263	PTS System
IMZ18_14310	COG0024	Methionine aminopeptidase
IMZ18_14330	COG2258	MOSC domain
IMZ18_14335	COG1254	Belongs to the acylphosphatase family
IMZ18_14340	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IMZ18_14345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMZ18_14350	COG2851	Citrate transporter
IMZ18_14355	COG3181	Tripartite tricarboxylate transporter family receptor
IMZ18_14360	COG4565	transcriptional regulatory protein
IMZ18_14365	COG3290	protein histidine kinase activity
IMZ18_14370	COG0471	metal ion transport
IMZ18_14375	COG3866	Pectate lyase
IMZ18_14385	COG0513	Belongs to the DEAD box helicase family
IMZ18_14390	COG0488	(ABC) transporter
IMZ18_14405	COG2814	Major facilitator Superfamily
IMZ18_14410	COG0789	Transcriptional regulator
IMZ18_14420	COG0488	(ABC) transporter
IMZ18_14425	COG0840	transmembrane signaling receptor activity
IMZ18_14430	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_14435	COG0531	amino acid
IMZ18_14440	COG1011	Hydrolase
IMZ18_14445	COG2223	nitrite transmembrane transporter activity
IMZ18_14450	COG1442	glycosyl transferase family 8
IMZ18_14455	COG1216	Glycosyl transferase, family 2
IMZ18_14460	COG1442	glycosyl transferase family 8
IMZ18_14465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IMZ18_14470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IMZ18_14475	COG1368	sulfuric ester hydrolase activity
IMZ18_14480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IMZ18_14480	COG2124	cytochrome p450
IMZ18_14495	COG3328	transposase activity
IMZ18_14505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IMZ18_14510	COG0670	Belongs to the BI1 family
IMZ18_14515	COG5583	Uncharacterized small protein (DUF2292)
IMZ18_14530	COG0346	lactoylglutathione lyase activity
IMZ18_14535	COG2329	Antibiotic biosynthesis monooxygenase
IMZ18_14540	COG2323	membrane
IMZ18_14545	COG1486	melibiose metabolic process
IMZ18_14550	COG0395	ABC-type sugar transport system, permease component
IMZ18_14555	COG4209	transmembrane transport
IMZ18_14560	COG1653	transport
IMZ18_14575	COG2755	lipolytic protein G-D-S-L family
IMZ18_14580	COG3401	FG-GAP repeat protein
IMZ18_14585	COG3401	FG-GAP repeat protein
IMZ18_14590	COG5578	integral membrane protein
IMZ18_14600	COG2755	lipolytic protein G-D-S-L family
IMZ18_14605	COG2207	Transcriptional regulator
IMZ18_14610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IMZ18_14615	COG0395	ABC-type sugar transport system, permease component
IMZ18_14620	COG1175	transmembrane transport
IMZ18_14625	COG1653	transport
IMZ18_14635	COG2972	Histidine kinase
IMZ18_14640	COG5578	integral membrane protein
IMZ18_14650	COG0454	-acetyltransferase
IMZ18_14655	COG3546	catalase activity
IMZ18_14670	COG1309	transcriptional regulator
IMZ18_14680	COG0217	transcriptional regulatory protein
IMZ18_14690	COG0457	Tetratricopeptide repeat
IMZ18_14700	COG5444	nuclease activity
IMZ18_14730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMZ18_14735	COG1597	lipid kinase activity
IMZ18_14740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IMZ18_14745	COG1309	transcriptional regulator
IMZ18_14755	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMZ18_14760	COG0154	amidase activity
IMZ18_14765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMZ18_14770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ18_14775	COG1285	pathogenesis
IMZ18_14780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IMZ18_14795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMZ18_14800	COG0210	DNA helicase
IMZ18_14805	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IMZ18_14810	COG0069	glutamate synthase activity
IMZ18_14815	COG4496	protein, YerC YecD
IMZ18_14820	COG1470	cell adhesion involved in biofilm formation
IMZ18_14825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMZ18_14835	COG0531	amino acid
IMZ18_14840	COG1522	sequence-specific DNA binding
IMZ18_14845	COG0151	Belongs to the GarS family
IMZ18_14855	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMZ18_14860	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMZ18_14865	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMZ18_14870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMZ18_14875	COG0047	phosphoribosylformylglycinamidine synthase activity
IMZ18_14880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMZ18_14885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IMZ18_14890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMZ18_14895	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IMZ18_14900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMZ18_14910	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IMZ18_14920	COG3064	Membrane
IMZ18_14925	COG2252	PERMEase
IMZ18_14935	COG0519	Catalyzes the synthesis of GMP from XMP
IMZ18_14935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IMZ18_14940	COG1305	Transglutaminase-like
IMZ18_14945	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
IMZ18_14950	COG0714	Associated with various cellular activities
IMZ18_14955	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMZ18_14965	COG1113	amino acid transport
IMZ18_14970	COG2132	Multicopper oxidase
IMZ18_14980	COG2267	carboxylic ester hydrolase activity
IMZ18_15000	COG0823	Involved in the tonB-independent uptake of proteins
IMZ18_15005	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IMZ18_15010	COG1063	alcohol dehydrogenase
IMZ18_15015	COG2814	Major facilitator Superfamily
IMZ18_15025	COG4260	virion core protein, lumpy skin disease virus
IMZ18_15030	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IMZ18_15035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMZ18_15045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ18_15050	COG2211	Major facilitator Superfamily
IMZ18_15055	COG1063	alcohol dehydrogenase
IMZ18_15060	COG0457	Tetratricopeptide repeat
IMZ18_15075	COG0459	protein refolding
IMZ18_15085	COG1266	CAAX protease self-immunity
IMZ18_15095	COG0805	protein transport
IMZ18_15100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMZ18_15105	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IMZ18_15110	COG0315	cyclic pyranopterin monophosphate synthase activity
IMZ18_15115	COG0488	(ABC) transporter
IMZ18_15120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMZ18_15125	COG0456	acetyltransferase
IMZ18_15130	COG1214	PFAM Peptidase M22, glycoprotease
IMZ18_15135	COG0802	atpase or kinase
IMZ18_15140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IMZ18_15185	COG4124	Belongs to the glycosyl hydrolase 26 family
IMZ18_15195	COG1940	carbohydrate kinase activity
IMZ18_15200	COG2188	Transcriptional regulator
IMZ18_15205	COG2723	6-phospho-beta-galactosidase activity
IMZ18_15220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMZ18_15225	COG2814	Major facilitator Superfamily
IMZ18_15230	COG1388	LysM domain
IMZ18_15235	COG1078	dGTPase activity
IMZ18_15240	COG0454	-acetyltransferase
IMZ18_15250	COG5646	InterPro IPR014922
IMZ18_15255	COG1785	Belongs to the alkaline phosphatase family
IMZ18_15265	COG1819	glycosyl
IMZ18_15270	COG1388	LysM domain
IMZ18_15270	COG3858	chitin binding
IMZ18_15275	COG1802	Transcriptional regulator
IMZ18_15280	COG0730	response to heat
IMZ18_15285	COG2814	Major facilitator Superfamily
IMZ18_15290	COG1846	Transcriptional regulator
IMZ18_15295	COG0778	Nitroreductase
IMZ18_15300	COG2409	Drug exporters of the RND superfamily
IMZ18_15300	COG1033	growth of symbiont in host cell
IMZ18_15305	COG1846	Transcriptional regulator
IMZ18_15310	COG2318	DinB family
IMZ18_15315	COG1113	amino acid transport
IMZ18_15320	COG0488	(ABC) transporter
IMZ18_15325	COG0456	acetyltransferase
IMZ18_15335	COG1309	transcriptional regulator
IMZ18_15350	COG0071	Belongs to the small heat shock protein (HSP20) family
IMZ18_15355	COG2323	membrane
IMZ18_15380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_15385	COG2259	Doxx family
IMZ18_15390	COG0346	lactoylglutathione lyase activity
IMZ18_15395	COG0778	Nitroreductase
IMZ18_15400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMZ18_15405	COG0789	Transcriptional regulator
IMZ18_15405	COG4978	Transcriptional regulator
IMZ18_15420	COG2409	Drug exporters of the RND superfamily
IMZ18_15425	COG2197	response regulator
IMZ18_15430	COG4585	Histidine kinase
IMZ18_15445	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IMZ18_15450	COG0640	Transcriptional regulator
IMZ18_15455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMZ18_15460	COG0076	glutamate decarboxylase activity
IMZ18_15465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ18_15470	COG0697	spore germination
IMZ18_15475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_15485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMZ18_15490	COG0640	Transcriptional regulator
IMZ18_15495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMZ18_15505	COG3545	Serine hydrolase
IMZ18_15510	COG2030	dehydratase
IMZ18_15515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ18_15520	COG0697	spore germination
IMZ18_15525	COG1309	transcriptional regulator
IMZ18_15530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_15545	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
IMZ18_15565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ18_15570	COG3708	Transcriptional regulator
IMZ18_15570	COG2207	Transcriptional regulator
IMZ18_15580	COG1917	Cupin 2, conserved barrel domain protein
IMZ18_15580	COG2207	Transcriptional regulator
IMZ18_15585	COG0697	spore germination
IMZ18_15590	COG1329	Transcriptional regulator
IMZ18_15595	COG1278	Cold shock
IMZ18_15600	COG0693	protein deglycase activity
IMZ18_15620	COG1476	TRANSCRIPTIONal
IMZ18_15625	COG5444	nuclease activity
IMZ18_15635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_15640	COG0583	DNA-binding transcription factor activity
IMZ18_15670	COG0457	Tetratricopeptide repeat
IMZ18_15685	COG0791	NLP P60 protein
IMZ18_15685	COG0741	lytic transglycosylase activity
IMZ18_15695	COG5644	endopeptidase inhibitor activity
IMZ18_15705	COG0433	COG0433 Predicted ATPase
IMZ18_15745	COG2946	Replication initiation factor
IMZ18_15750	COG1674	ftsk spoiiie
IMZ18_15780	COG1396	sequence-specific DNA binding
IMZ18_15785	COG2856	Zn peptidase
IMZ18_15790	COG0582	viral genome integration into host DNA
IMZ18_15830	COG3091	SprT-like family
IMZ18_15840	COG2183	response to ionizing radiation
IMZ18_15845	COG1846	Transcriptional regulator
IMZ18_15850	COG1673	EVE domain
IMZ18_15865	COG2208	phosphoserine phosphatase activity
IMZ18_15870	COG1191	sigma factor activity
IMZ18_15875	COG2172	sigma factor antagonist activity
IMZ18_15880	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_15885	COG2208	phosphoserine phosphatase activity
IMZ18_15890	COG2172	sigma factor antagonist activity
IMZ18_15895	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_15900	COG1366	Belongs to the anti-sigma-factor antagonist family
IMZ18_15905	COG2337	Toxic component of a toxin-antitoxin (TA) module
IMZ18_15910	COG0864	Transcriptional regulator
IMZ18_15915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IMZ18_15920	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IMZ18_15925	COG0736	holo-[acyl-carrier-protein] synthase activity
IMZ18_15930	COG0705	Rhomboid family
IMZ18_15935	COG3428	Bacterial PH domain
IMZ18_15940	COG3402	PFAM membrane-flanked domain
IMZ18_15945	COG0513	Belongs to the DEAD box helicase family
IMZ18_15950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMZ18_15955	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMZ18_15960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IMZ18_15965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMZ18_15980	COG1960	acyl-CoA dehydrogenase activity
IMZ18_15990	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IMZ18_15995	COG1131	(ABC) transporter
IMZ18_16005	COG0628	permease
IMZ18_16010	COG1301	dicarboxylic acid transport
IMZ18_16015	COG4565	transcriptional regulatory protein
IMZ18_16020	COG3290	protein histidine kinase activity
IMZ18_16025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IMZ18_16030	COG3546	catalase activity
IMZ18_16035	COG2329	Antibiotic biosynthesis monooxygenase
IMZ18_16040	COG0662	Cupin 2, conserved barrel domain protein
IMZ18_16045	COG3729	General stress protein
IMZ18_16050	COG2217	Heavy metal translocating P-type atpase
IMZ18_16055	COG4876	unkown
IMZ18_16060	COG2261	transglycosylase associated protein
IMZ18_16065	COG1914	H( )-stimulated, divalent metal cation uptake system
IMZ18_16090	COG0028	Belongs to the TPP enzyme family
IMZ18_16095	COG0494	nUDIX hydrolase
IMZ18_16100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMZ18_16100	COG0551	DNA topoisomerase type I activity
IMZ18_16105	COG1522	sequence-specific DNA binding
IMZ18_16110	COG2814	Major facilitator Superfamily
IMZ18_16120	COG3871	stress protein (general stress protein 26)
IMZ18_16125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_16135	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_16140	COG2226	methyltransferase
IMZ18_16145	COG0318	PFAM AMP-dependent synthetase and ligase
IMZ18_16150	COG3711	transcriptional antiterminator
IMZ18_16155	COG4989	oxidoreductase activity
IMZ18_16160	COG0768	penicillin binding
IMZ18_16165	COG2329	Antibiotic biosynthesis monooxygenase
IMZ18_16175	COG2755	lipolytic protein G-D-S-L family
IMZ18_16180	COG1414	Transcriptional regulator
IMZ18_16185	COG1984	allophanate hydrolase subunit 2
IMZ18_16190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IMZ18_16195	COG4336	lyase activity
IMZ18_16200	COG1914	H( )-stimulated, divalent metal cation uptake system
IMZ18_16205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IMZ18_16210	COG0561	phosphatase activity
IMZ18_16220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMZ18_16230	COG0681	Belongs to the peptidase S26 family
IMZ18_16235	COG0473	3-isopropylmalate dehydrogenase activity
IMZ18_16240	COG0246	Mannitol dehydrogenase
IMZ18_16255	COG1349	DNA-binding transcription factor activity
IMZ18_16260	COG2372	response to copper ion
IMZ18_16260	COG1276	copper resistance
IMZ18_16265	COG4549	nuclear export factor GLE1
IMZ18_16270	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_16280	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_16285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IMZ18_16290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ18_16295	COG0640	Transcriptional regulator
IMZ18_16300	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IMZ18_16305	COG0778	Nitroreductase
IMZ18_16310	COG1309	transcriptional regulator
IMZ18_16315	COG2814	Major facilitator Superfamily
IMZ18_16325	COG4607	ABC-type enterochelin transport system periplasmic component
IMZ18_16330	COG4604	ABC transporter, ATP-binding protein
IMZ18_16335	COG4605	iron ion homeostasis
IMZ18_16340	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ18_16345	COG0527	aspartate kinase activity
IMZ18_16365	COG0457	Tetratricopeptide repeat
IMZ18_16370	COG5002	protein histidine kinase activity
IMZ18_16370	COG3850	Histidine kinase
IMZ18_16375	COG0745	RESPONSE REGULATOR receiver
IMZ18_16380	COG0577	efflux transmembrane transporter activity
IMZ18_16385	COG1136	(ABC) transporter
IMZ18_16390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IMZ18_16410	COG5434	Belongs to the glycosyl hydrolase 28 family
IMZ18_16415	COG3104	oligopeptide transport
IMZ18_16420	COG0596	Alpha beta hydrolase
IMZ18_16435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IMZ18_16440	COG0163	prenyltransferase activity
IMZ18_16445	COG0583	DNA-binding transcription factor activity
IMZ18_16450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMZ18_16455	COG0765	amino acid transport
IMZ18_16460	COG1126	abc transporter atp-binding protein
IMZ18_16465	COG2364	Membrane
IMZ18_16475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMZ18_16480	COG0697	spore germination
IMZ18_16495	COG2814	Major facilitator Superfamily
IMZ18_16500	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IMZ18_16510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMZ18_16515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMZ18_16520	COG1733	regulation of RNA biosynthetic process
IMZ18_16525	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IMZ18_16530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IMZ18_16540	COG3209	COG3209 Rhs family protein
IMZ18_16550	COG2723	6-phospho-beta-galactosidase activity
IMZ18_16565	COG1846	Transcriptional regulator
IMZ18_16575	COG1714	RDD family
IMZ18_16585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMZ18_16590	COG0765	amino acid transport
IMZ18_16605	COG1376	ErfK ybiS ycfS ynhG family protein
IMZ18_16615	COG2223	nitrite transmembrane transporter activity
IMZ18_16620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMZ18_16625	COG0243	molybdopterin cofactor binding
IMZ18_16630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IMZ18_16635	COG2146	nitrite reductase [NAD(P)H] activity
IMZ18_16640	COG1587	Uroporphyrinogen-III synthase
IMZ18_16640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IMZ18_16645	COG0492	ferredoxin-NADP+ reductase activity
IMZ18_16650	COG2267	carboxylic ester hydrolase activity
IMZ18_16655	COG0701	Predicted permease
IMZ18_16660	COG3689	TIGRFAM TIGR03943 family protein
IMZ18_16665	COG2508	Transcriptional regulator
IMZ18_16670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ18_16675	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_16680	COG0506	proline dehydrogenase activity
IMZ18_16685	COG3541	Predicted nucleotidyltransferase
IMZ18_16690	COG3458	cephalosporin-C deacetylase activity
IMZ18_16695	COG0583	DNA-binding transcription factor activity
IMZ18_16700	COG2226	methyltransferase
IMZ18_16710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMZ18_16715	COG1660	Displays ATPase and GTPase activities
IMZ18_16720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IMZ18_16735	COG3403	YqcI/YcgG family
IMZ18_16750	COG0039	L-malate dehydrogenase activity
IMZ18_16765	COG1288	antiporter activity
IMZ18_16770	COG1473	amidohydrolase
IMZ18_16775	COG2113	Glycine betaine
IMZ18_16780	COG4176	ABC-type proline glycine betaine transport system permease component
IMZ18_16785	COG4175	Glycine betaine
IMZ18_16785	COG0517	IMP dehydrogenase activity
IMZ18_16790	COG0640	Transcriptional regulator
IMZ18_16795	COG2814	Major facilitator Superfamily
IMZ18_16800	COG0477	Major facilitator Superfamily
IMZ18_16810	COG3853	Toxic anion resistance protein (TelA)
IMZ18_16820	COG0861	Integral membrane protein TerC family
IMZ18_16825	COG2310	stress, protein
IMZ18_16830	COG2310	stress, protein
IMZ18_16835	COG2310	stress, protein
IMZ18_16845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMZ18_16850	COG1121	(ABC) transporter
IMZ18_16855	COG0803	Belongs to the bacterial solute-binding protein 9 family
IMZ18_16860	COG0366	Alpha amylase catalytic
IMZ18_16865	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_16875	COG1876	peptidase activity
IMZ18_16880	COG1595	DNA-templated transcription, initiation
IMZ18_16885	COG1595	DNA-templated transcription, initiation
IMZ18_16905	COG0667	Aldo Keto reductase
IMZ18_16910	COG1668	transmembrane transport
IMZ18_16920	COG3279	Response regulator of the LytR AlgR family
IMZ18_16930	COG1405	negative regulation of cell septum assembly
IMZ18_16930	COG3012	SEC-C Motif Domain Protein
IMZ18_16935	COG1714	RDD family
IMZ18_16940	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IMZ18_16945	COG0252	asparaginase activity
IMZ18_16950	COG1309	transcriptional regulator
IMZ18_16955	COG0477	Major facilitator Superfamily
IMZ18_16960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IMZ18_16965	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IMZ18_16970	COG0805	protein transport
IMZ18_16975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IMZ18_16980	COG3540	Alkaline phosphatase
IMZ18_16990	COG2304	oxidoreductase activity
IMZ18_16995	COG3773	Cell wall hydrolase
IMZ18_17015	COG1131	(ABC) transporter
IMZ18_17020	COG2205	protein histidine kinase activity
IMZ18_17025	COG0745	RESPONSE REGULATOR receiver
IMZ18_17030	COG0697	spore germination
IMZ18_17040	COG3173	Aminoglycoside phosphotransferase
IMZ18_17045	COG2721	sulfolactate sulfo-lyase activity
IMZ18_17050	COG2186	Transcriptional regulator
IMZ18_17055	COG4948	Mandelate Racemase Muconate Lactonizing
IMZ18_17060	COG2271	Major facilitator Superfamily
IMZ18_17065	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_17070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IMZ18_17075	COG0784	Response regulator, receiver
IMZ18_17080	COG4191	Histidine kinase
IMZ18_17085	COG2066	Belongs to the glutaminase family
IMZ18_17095	COG2040	homocysteine
IMZ18_17100	COG0833	amino acid
IMZ18_17105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMZ18_17115	COG2188	Transcriptional regulator
IMZ18_17120	COG0363	glucosamine-6-phosphate deaminase activity
IMZ18_17125	COG2190	(PTS) system
IMZ18_17125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_17125	COG1263	PTS System
IMZ18_17130	COG1301	dicarboxylic acid transport
IMZ18_17140	COG1054	Belongs to the UPF0176 family
IMZ18_17145	COG2207	Transcriptional regulator
IMZ18_17150	COG2312	Erythromycin esterase
IMZ18_17160	COG0688	phosphatidylethanolamine metabolic process
IMZ18_17165	COG0586	Pfam SNARE associated Golgi protein
IMZ18_17170	COG1183	phosphatidylcholine synthase activity
IMZ18_17175	COG0596	Alpha beta hydrolase
IMZ18_17185	COG3591	Belongs to the peptidase S1B family
IMZ18_17190	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IMZ18_17215	COG1917	Cupin 2, conserved barrel domain protein
IMZ18_17215	COG2207	Transcriptional regulator
IMZ18_17220	COG0697	spore germination
IMZ18_17225	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_17240	COG0456	acetyltransferase
IMZ18_17240	COG1846	Transcriptional regulator
IMZ18_17250	COG2271	Major facilitator Superfamily
IMZ18_17255	COG0584	glycerophosphoryl diester phosphodiesterase
IMZ18_17260	COG0531	amino acid
IMZ18_17270	COG2124	cytochrome p450
IMZ18_17275	COG2602	Beta-lactamase
IMZ18_17290	COG1113	amino acid transport
IMZ18_17305	COG0515	serine threonine protein kinase
IMZ18_17315	COG0642	Histidine kinase
IMZ18_17325	COG5609	conserved protein (DUF2294)
IMZ18_17335	COG0288	reversible hydration of carbon dioxide
IMZ18_17340	COG3002	Belongs to the UPF0753 family
IMZ18_17345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IMZ18_17350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMZ18_17355	COG2169	Transcriptional regulator
IMZ18_17370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMZ18_17375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMZ18_17380	COG4856	YbbR-like protein
IMZ18_17385	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IMZ18_17390	COG5662	AntiSigma factor
IMZ18_17395	COG1595	DNA-templated transcription, initiation
IMZ18_17425	COG1683	Conserved Protein
IMZ18_17430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMZ18_17435	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IMZ18_17440	COG1737	Transcriptional regulator
IMZ18_17445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_17445	COG1263	PTS System
IMZ18_17450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IMZ18_17455	COG1472	Belongs to the glycosyl hydrolase 3 family
IMZ18_17460	COG3876	Protein conserved in bacteria
IMZ18_17465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ18_17465	COG2207	Transcriptional regulator
IMZ18_17470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ18_17475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ18_17480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IMZ18_17485	COG2819	hydrolase of the alpha beta superfamily
IMZ18_17490	COG0385	Bile acid
IMZ18_17495	COG0659	secondary active sulfate transmembrane transporter activity
IMZ18_17575	COG0726	polysaccharide deacetylase
IMZ18_17580	COG2194	sulfuric ester hydrolase activity
IMZ18_17590	COG0489	protein tyrosine kinase activity
IMZ18_17595	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMZ18_17605	COG2226	methyltransferase
IMZ18_17610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMZ18_17615	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMZ18_17620	COG0101	tRNA pseudouridine synthase activity
IMZ18_17625	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IMZ18_17630	COG1122	ATPase activity
IMZ18_17635	COG1122	ATPase activity
IMZ18_17640	COG0203	ribosomal protein L17
IMZ18_17645	COG0202	RNA polymerase activity
IMZ18_17650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMZ18_17655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMZ18_17660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IMZ18_17675	COG0024	Methionine aminopeptidase
IMZ18_17680	COG0563	adenylate kinase activity
IMZ18_17685	COG0201	protein transport
IMZ18_17690	COG0200	Binds to the 23S rRNA
IMZ18_17700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMZ18_17705	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMZ18_17710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMZ18_17715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMZ18_17725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IMZ18_17735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMZ18_17740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMZ18_17750	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMZ18_17755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMZ18_17770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IMZ18_17780	COG0088	Forms part of the polypeptide exit tunnel
IMZ18_17785	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMZ18_17795	COG0596	Alpha beta hydrolase
IMZ18_17800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMZ18_17805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMZ18_17810	COG0049	tRNA binding
IMZ18_17815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMZ18_17820	COG1358	cellular component organization or biogenesis
IMZ18_17825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMZ18_17830	COG0085	RNA polymerase activity
IMZ18_17835	COG2813	Specifically methylates the guanine in position
IMZ18_17845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IMZ18_17850	COG0081	regulation of translation
IMZ18_17860	COG0250	Participates in transcription elongation, termination and antitermination
IMZ18_17865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IMZ18_17875	COG1595	DNA-templated transcription, initiation
IMZ18_17880	COG3688	RNA-binding protein containing a PIN domain
IMZ18_17885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMZ18_17890	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMZ18_17895	COG0215	cysteine-tRNA ligase activity
IMZ18_17900	COG1045	serine acetyltransferase
IMZ18_17905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMZ18_17910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IMZ18_17915	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IMZ18_17920	COG4956	integral membrane protein (PIN domain superfamily)
IMZ18_17925	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IMZ18_17930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMZ18_17935	COG0542	response to heat
IMZ18_17940	COG3869	Catalyzes the specific phosphorylation of arginine residues in
IMZ18_17945	COG3880	PFAM UvrB UvrC protein
IMZ18_17950	COG4463	regulation of RNA biosynthetic process
IMZ18_18025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMZ18_18030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMZ18_18035	COG1396	sequence-specific DNA binding
IMZ18_18040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMZ18_18045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMZ18_18050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMZ18_18055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMZ18_18065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IMZ18_18070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMZ18_18075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMZ18_18080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IMZ18_18085	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IMZ18_18090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMZ18_18095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMZ18_18100	COG0037	tRNA processing
IMZ18_18110	COG2304	oxidoreductase activity
IMZ18_18115	COG2208	phosphoserine phosphatase activity
IMZ18_18130	COG1098	S1 RNA binding domain
IMZ18_18135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IMZ18_18150	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IMZ18_18155	COG3956	TIGRFAM MazG family protein
IMZ18_18160	COG2244	polysaccharide biosynthetic process
IMZ18_18165	COG2002	toxin-antitoxin pair type II binding
IMZ18_18170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMZ18_18180	COG0193	aminoacyl-tRNA hydrolase activity
IMZ18_18185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IMZ18_18190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMZ18_18195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IMZ18_18200	COG2088	sporulation resulting in formation of a cellular spore
IMZ18_18205	COG0251	oxidation-reduction process
IMZ18_18210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMZ18_18215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMZ18_18225	COG4466	Protein conserved in bacteria
IMZ18_18235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMZ18_18240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IMZ18_18245	COG3583	domain protein
IMZ18_18245	COG3584	3D domain protein
IMZ18_18250	COG0084	hydrolase, TatD family'
IMZ18_18255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ18_18255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMZ18_18260	COG2002	toxin-antitoxin pair type II binding
IMZ18_18265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMZ18_18270	COG2827	Endonuclease containing a URI domain
IMZ18_18275	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IMZ18_18280	COG4467	Involved in initiation control of chromosome replication
IMZ18_18285	COG1774	PSP1 C-terminal conserved region
IMZ18_18290	COG0470	DNA polymerase III
IMZ18_18295	COG1728	Protein conserved in bacteria
IMZ18_18300	COG3870	Protein conserved in bacteria
IMZ18_18305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IMZ18_18310	COG1982	Orn Lys Arg decarboxylase major
IMZ18_18315	COG3853	Toxic anion resistance protein (TelA)
IMZ18_18320	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IMZ18_18365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMZ18_18370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMZ18_18375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMZ18_18385	COG0590	tRNA wobble adenosine to inosine editing
IMZ18_18390	COG1335	isochorismatase
IMZ18_18395	COG3858	chitin binding
IMZ18_18395	COG1388	LysM domain
IMZ18_18400	COG1428	Deoxynucleoside kinase
IMZ18_18405	COG1428	Deoxynucleoside kinase
IMZ18_18415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMZ18_18420	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IMZ18_18425	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IMZ18_18430	COG1686	Belongs to the peptidase S11 family
IMZ18_18435	COG0516	GMP reductase activity
IMZ18_18435	COG0517	IMP dehydrogenase activity
IMZ18_18475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMZ18_18480	COG0187	DNA topoisomerase II activity
IMZ18_18490	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMZ18_18495	COG2501	S4 domain
IMZ18_18500	COG0592	DNA-directed DNA polymerase activity
IMZ18_18505	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IMZ18_18515	COG0594	ribonuclease P activity
IMZ18_18520	COG0706	membrane insertase activity
IMZ18_18525	COG1847	R3H domain protein
IMZ18_18530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMZ18_18535	COG0445	tRNA wobble uridine modification
IMZ18_18540	COG0357	Ribosomal RNA small subunit methyltransferase G
IMZ18_18545	COG1475	DNA binding
IMZ18_18555	COG1192	Involved in chromosome partitioning
IMZ18_18560	COG1475	DNA binding
IMZ18_18570	COG3949	Membrane
IMZ18_18575	COG4481	Protein conserved in bacteria
IMZ18_18580	COG0243	molybdopterin cofactor binding
IMZ18_18585	COG0012	GTP binding
IMZ18_18590	COG0360	Binds together with S18 to 16S ribosomal RNA
IMZ18_18595	COG0629	single-stranded DNA binding
IMZ18_18600	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMZ18_18605	COG0708	Exodeoxyribonuclease III
IMZ18_18620	COG0542	response to heat
IMZ18_18625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IMZ18_18630	COG0346	lactoylglutathione lyase activity
IMZ18_18635	COG0477	Major facilitator Superfamily
IMZ18_18635	COG2814	Major facilitator Superfamily
IMZ18_18640	COG1266	CAAX protease self-immunity
IMZ18_18650	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IMZ18_18655	COG1331	Highly conserved protein containing a thioredoxin domain
IMZ18_18660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMZ18_18665	COG2315	Protein conserved in bacteria
IMZ18_18670	COG0456	acetyltransferase
IMZ18_18675	COG2364	Membrane
IMZ18_18680	COG2153	protein acetylation
IMZ18_18685	COG1846	Transcriptional regulator
IMZ18_18700	COG1357	PFAM Pentapeptide repeats (8 copies)
IMZ18_18705	COG4319	ketosteroid isomerase
IMZ18_18715	COG4978	Transcriptional regulator
IMZ18_18715	COG0789	Transcriptional regulator
IMZ18_18720	COG2271	Major facilitator Superfamily
IMZ18_18740	COG1227	inorganic diphosphatase activity
IMZ18_18745	COG1733	regulation of RNA biosynthetic process
IMZ18_18760	COG4241	membrane
IMZ18_18765	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IMZ18_18770	COG0359	binds to the 23S rRNA
IMZ18_18775	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IMZ18_18780	COG2807	transmembrane transport
IMZ18_18785	COG3093	addiction module antidote protein HigA
IMZ18_18800	COG0305	Participates in initiation and elongation during chromosome replication
IMZ18_18805	COG0346	lactoylglutathione lyase activity
IMZ18_18835	COG0745	RESPONSE REGULATOR receiver
IMZ18_18840	COG5002	protein histidine kinase activity
IMZ18_18845	COG4863	YycH protein
IMZ18_18850	COG4853	Protein conserved in bacteria
IMZ18_18855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IMZ18_18860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMZ18_18875	COG3829	transcription factor binding
IMZ18_18880	COG0640	Transcriptional regulator
IMZ18_18885	COG5658	integral membrane protein
IMZ18_18905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMZ18_18910	COG0833	amino acid
IMZ18_18915	COG0010	Belongs to the arginase family
IMZ18_18925	COG0457	Tetratricopeptide repeat
IMZ18_18930	COG0456	acetyltransferase
IMZ18_18935	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IMZ18_18955	COG1063	alcohol dehydrogenase
IMZ18_18970	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMZ18_19005	COG2963	transposase activity
IMZ18_19035	COG0210	DNA helicase
IMZ18_19065	COG0071	Belongs to the small heat shock protein (HSP20) family
IMZ18_19080	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IMZ18_19085	COG1131	(ABC) transporter
IMZ18_19095	COG2188	Transcriptional regulator
IMZ18_19105	COG2723	6-phospho-beta-galactosidase activity
IMZ18_19110	COG3634	alkyl hydroperoxide reductase activity
IMZ18_19115	COG0450	alkyl hydroperoxide reductase
IMZ18_19120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMZ18_19130	COG1070	Carbohydrate kinase
IMZ18_19135	COG1802	Transcriptional regulator
IMZ18_19140	COG1929	Belongs to the glycerate kinase type-1 family
IMZ18_19145	COG5039	Polysaccharide pyruvyl transferase
IMZ18_19150	COG1346	cytolysis
IMZ18_19155	COG1380	Effector of murein hydrolase LrgA
IMZ18_19160	COG1846	Transcriptional regulator
IMZ18_19165	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_19170	COG1309	transcriptional regulator
IMZ18_19175	COG1917	Cupin 2, conserved barrel domain protein
IMZ18_19230	COG0326	Molecular chaperone. Has ATPase activity
IMZ18_19260	COG0667	Aldo Keto reductase
IMZ18_19265	COG1349	DNA-binding transcription factor activity
IMZ18_19285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ18_19290	COG3962	Belongs to the TPP enzyme family
IMZ18_19295	COG1082	Xylose isomerase domain protein TIM barrel
IMZ18_19300	COG2814	Major facilitator Superfamily
IMZ18_19305	COG0673	inositol 2-dehydrogenase activity
IMZ18_19310	COG1082	Xylose isomerase domain protein TIM barrel
IMZ18_19315	COG1082	Xylose isomerase domain protein TIM barrel
IMZ18_19320	COG0191	fructose-bisphosphate aldolase activity
IMZ18_19325	COG0745	RESPONSE REGULATOR receiver
IMZ18_19330	COG2205	protein histidine kinase activity
IMZ18_19345	COG5294	Protein conserved in bacteria
IMZ18_19350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IMZ18_19380	COG0561	phosphatase activity
IMZ18_19385	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IMZ18_19390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMZ18_19395	COG0456	acetyltransferase
IMZ18_19400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMZ18_19405	COG0765	amino acid transport
IMZ18_19410	COG1126	abc transporter atp-binding protein
IMZ18_19415	COG1473	amidohydrolase
IMZ18_19420	COG2079	MmgE PrpD family protein
IMZ18_19425	COG3192	ethanolamine utilization protein
IMZ18_19435	COG2390	Transcriptional regulator
IMZ18_19440	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IMZ18_19445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMZ18_19450	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IMZ18_19465	COG3507	Belongs to the glycosyl hydrolase 43 family
IMZ18_19470	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IMZ18_19475	COG0494	nUDIX hydrolase
IMZ18_19495	COG5444	nuclease activity
IMZ18_19525	COG0589	response to stress
IMZ18_19540	COG0697	spore germination
IMZ18_19655	COG2755	lipolytic protein G-D-S-L family
IMZ18_19655	COG3401	FG-GAP repeat protein
IMZ18_19660	COG0513	Belongs to the DEAD box helicase family
IMZ18_19665	COG2270	Major facilitator Superfamily
IMZ18_19675	COG3711	transcriptional antiterminator
IMZ18_19680	COG2273	Hydrolase Family 16
IMZ18_19685	COG2851	Citrate transporter
IMZ18_19690	COG0693	protein deglycase activity
IMZ18_19690	COG0753	catalase activity
IMZ18_19705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMZ18_19710	COG0500	methyltransferase
IMZ18_19715	COG2610	gluconate transmembrane transporter activity
IMZ18_19720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IMZ18_19725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IMZ18_19730	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_19735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMZ18_19740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMZ18_19745	COG4894	glucomannan catabolic process
IMZ18_19755	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMZ18_19760	COG2197	response regulator
IMZ18_19765	COG4585	Histidine kinase
IMZ18_19775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMZ18_19780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMZ18_19785	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_19790	COG2508	Transcriptional regulator
IMZ18_19795	COG3842	ATPase activity
IMZ18_19810	COG0726	polysaccharide deacetylase
IMZ18_19820	COG0501	Belongs to the peptidase M48B family
IMZ18_19825	COG3493	citrate carrier protein
IMZ18_19830	COG1271	oxidase subunit
IMZ18_19835	COG1294	oxidase, subunit
IMZ18_19840	COG4988	ABC transporter
IMZ18_19845	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IMZ18_19850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMZ18_19855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IMZ18_19860	COG1595	DNA-templated transcription, initiation
IMZ18_19880	COG1131	(ABC) transporter
IMZ18_19885	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IMZ18_19890	COG2814	Major facilitator Superfamily
IMZ18_19895	COG0753	catalase activity
IMZ18_19900	COG2094	Belongs to the DNA glycosylase MPG family
IMZ18_19910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMZ18_19910	COG3711	transcriptional antiterminator
IMZ18_19915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMZ18_19920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMZ18_19925	COG1447	Phosphotransferase system cellobiose-specific component IIA
IMZ18_19930	COG1486	melibiose metabolic process
IMZ18_19935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMZ18_19945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IMZ18_19950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMZ18_19955	COG1696	Membrane protein involved in D-alanine export
IMZ18_19960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IMZ18_19975	COG1575	Belongs to the MenA family. Type 1 subfamily
IMZ18_19985	COG2357	RelA SpoT domain protein
IMZ18_19995	COG2234	aminopeptidase activity
IMZ18_20000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMZ18_20005	COG1846	Transcriptional regulator
IMZ18_20010	COG5522	Integral membrane protein (intg_mem_TP0381)
IMZ18_20015	COG1442	glycosyl transferase family 8
IMZ18_20025	COG3711	transcriptional antiterminator
IMZ18_20030	COG1263	PTS System
IMZ18_20030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_20040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMZ18_20050	COG0346	lactoylglutathione lyase activity
IMZ18_20055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IMZ18_20060	COG4895	conserved protein (DUF2196)
IMZ18_20065	COG2814	Major facilitator Superfamily
IMZ18_20070	COG1346	cytolysis
IMZ18_20075	COG1380	Effector of murein hydrolase LrgA
IMZ18_20080	COG0583	DNA-binding transcription factor activity
IMZ18_20085	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IMZ18_20090	COG0352	thiamine-phosphate diphosphorylase activity
IMZ18_20095	COG0672	)-iron permease
IMZ18_20100	COG2822	iron ion transport
IMZ18_20105	COG2837	iron assimilation
IMZ18_20110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMZ18_20120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IMZ18_20125	COG3162	membrane
IMZ18_20135	COG1309	transcriptional regulator
IMZ18_20140	COG2246	polysaccharide biosynthetic process
IMZ18_20145	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMZ18_20150	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IMZ18_20155	COG2261	transglycosylase associated protein
IMZ18_20160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IMZ18_20165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IMZ18_20170	COG1845	cytochrome c oxidase, subunit III
IMZ18_20175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IMZ18_20190	COG0772	Belongs to the SEDS family
IMZ18_20195	COG0778	Nitroreductase
IMZ18_20200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMZ18_20205	COG1404	Belongs to the peptidase S8 family
IMZ18_20220	COG2116	formate transmembrane transporter activity
IMZ18_20225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMZ18_20225	COG1263	PTS System
IMZ18_20230	COG1621	beta-fructofuranosidase activity
IMZ18_20240	COG0351	phosphomethylpyrimidine kinase
IMZ18_20245	COG1216	Glycosyl transferase, family 2
IMZ18_20250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMZ18_20255	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_20265	COG2233	PERMEase
IMZ18_20270	COG2363	Small membrane protein
IMZ18_20280	COG0463	Glycosyl transferase, family 2
IMZ18_20285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ18_20290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMZ18_20295	COG0456	acetyltransferase
IMZ18_20300	COG2089	acid synthase
IMZ18_20305	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
IMZ18_20310	COG3980	spore coat polysaccharide biosynthesis protein
IMZ18_20315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMZ18_20320	COG1088	dTDP-glucose 4,6-dehydratase activity
IMZ18_20325	COG1091	dTDP-4-dehydrorhamnose reductase activity
IMZ18_20330	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IMZ18_20340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMZ18_20345	COG1012	belongs to the aldehyde dehydrogenase family
IMZ18_20350	COG4187	Peptidase family M20/M25/M40
IMZ18_20355	COG0833	amino acid
IMZ18_20360	COG2814	Major facilitator Superfamily
IMZ18_20365	COG0077	Prephenate dehydratase
IMZ18_20370	COG1917	Cupin 2, conserved barrel domain protein
IMZ18_20375	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_20380	COG0151	Belongs to the GarS family
IMZ18_20385	COG2814	Major facilitator Superfamily
IMZ18_20390	COG0436	Aminotransferase
IMZ18_20395	COG1028	Short-chain dehydrogenase reductase Sdr
IMZ18_20400	COG3253	May function as heme-dependent peroxidase
IMZ18_20405	COG0280	phosphate acetyltransferase
IMZ18_20410	COG0583	DNA-binding transcription factor activity
IMZ18_20415	COG0095	Lipoate-protein ligase
IMZ18_20420	COG0697	spore germination
IMZ18_20430	COG4844	belongs to the
IMZ18_20435	COG1078	dGTPase activity
IMZ18_20440	COG3465	dGTPase activity
IMZ18_20445	COG1959	2 iron, 2 sulfur cluster binding
IMZ18_20450	COG0477	Major facilitator Superfamily
IMZ18_20460	COG1846	Transcriptional regulator
IMZ18_20465	COG1942	4-Oxalocrotonate Tautomerase
IMZ18_20470	COG1994	Peptidase M50
IMZ18_20485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMZ18_20490	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IMZ18_20495	COG0010	Belongs to the arginase family
IMZ18_20500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMZ18_20510	COG0457	Tetratricopeptide repeat
IMZ18_20515	COG3391	amine dehydrogenase activity
IMZ18_20520	COG3391	amine dehydrogenase activity
IMZ18_20530	COG0612	Peptidase, M16
IMZ18_20535	COG0612	Peptidase, M16
IMZ18_20540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMZ18_20545	COG1131	(ABC) transporter
IMZ18_20555	COG0535	radical SAM domain protein
IMZ18_20570	COG4506	Protein conserved in bacteria
IMZ18_20575	COG0018	arginyl-trna synthetase
IMZ18_20580	COG2223	nitrite transmembrane transporter activity
IMZ18_20585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMZ18_20595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMZ18_20605	COG1140	nitrate reductase beta subunit
IMZ18_20610	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IMZ18_20615	COG2181	nitrate reductase activity
IMZ18_20625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMZ18_20635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMZ18_20645	COG4294	response to UV
IMZ18_20650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMZ18_20655	COG2181	nitrate reductase activity
IMZ18_20655	COG0247	lactate metabolic process
IMZ18_20665	COG3343	RNA polymerase activity
IMZ18_20670	COG0504	CTP synthase activity
IMZ18_20675	COG4821	SIS domain
IMZ18_20680	COG2204	response regulator
IMZ18_20685	COG0191	fructose-bisphosphate aldolase activity
IMZ18_20690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMZ18_20700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMZ18_20705	COG1494	fructose-1,6-bisphosphatase
IMZ18_20715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMZ18_20725	COG1435	thymidine kinase activity
IMZ18_20730	COG0281	malic enzyme
IMZ18_20735	COG0679	Auxin Efflux Carrier
IMZ18_20740	COG0789	Transcriptional regulator
IMZ18_20745	COG0346	lactoylglutathione lyase activity
IMZ18_20750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMZ18_20755	COG2890	protein-(glutamine-N5) methyltransferase activity
IMZ18_20775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IMZ18_20780	COG0009	L-threonylcarbamoyladenylate synthase
IMZ18_20785	COG1971	Probably functions as a manganese efflux pump
IMZ18_20790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IMZ18_20795	COG0698	ribose 5-phosphate isomerase
IMZ18_20800	COG4475	Protein of unknown function (DUF436)
IMZ18_20805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IMZ18_20810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMZ18_20820	COG0356	it plays a direct role in the translocation of protons across the membrane
IMZ18_20830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IMZ18_20835	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMZ18_20840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IMZ18_20845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IMZ18_20850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IMZ18_20855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IMZ18_20865	COG4836	Membrane
IMZ18_20875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMZ18_20880	COG2385	sporulation resulting in formation of a cellular spore
IMZ18_20885	COG2304	oxidoreductase activity
IMZ18_20895	COG2304	oxidoreductase activity
IMZ18_20905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IMZ18_20910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IMZ18_20915	COG0457	Tetratricopeptide repeat
IMZ18_20920	COG1994	Peptidase M50
IMZ18_20925	COG3237	CsbD-like
IMZ18_20945	COG0832	Belongs to the urease beta subunit family
IMZ18_20950	COG0804	urea catabolic process
IMZ18_20955	COG1959	2 iron, 2 sulfur cluster binding
IMZ18_20960	COG2910	NAD(P)H-binding
IMZ18_20970	COG0789	Transcriptional regulator
IMZ18_20975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMZ18_20985	COG2089	acid synthase
IMZ18_20995	COG1247	-acetyltransferase
IMZ18_21000	COG0739	heme binding
IMZ18_21010	COG0671	phosphoesterase, PA-phosphatase related
IMZ18_21015	COG0347	Belongs to the P(II) protein family
IMZ18_21020	COG0004	ammonium transporteR
IMZ18_21030	COG1335	isochorismatase
IMZ18_21035	COG0477	Major facilitator Superfamily
IMZ18_21040	COG1953	Uracil, thiamine, allantoin
IMZ18_21045	COG3420	alginic acid biosynthetic process
IMZ18_21050	COG2814	Major facilitator Superfamily
IMZ18_21055	COG1846	Transcriptional regulator
IMZ18_21065	COG1609	Transcriptional regulator
IMZ18_21070	COG1077	Cell shape determining protein MreB Mrl
IMZ18_21075	COG4786	Flagellar basal body rod
IMZ18_21080	COG4786	Flagellar basal body rod
IMZ18_21085	COG0457	Tetratricopeptide repeat
IMZ18_21090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMZ18_21095	COG1970	mechanosensitive ion channel activity
IMZ18_21100	COG2972	Histidine kinase
IMZ18_21100	COG0745	RESPONSE REGULATOR receiver
IMZ18_21110	COG3764	Sortase (surface protein transpeptidase)
IMZ18_21125	COG0629	single-stranded DNA binding
IMZ18_21130	COG1349	DNA-binding transcription factor activity
IMZ18_21135	COG0561	phosphatase activity
IMZ18_21140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IMZ18_21145	COG4715	Zinc finger, swim domain protein
IMZ18_21155	COG3944	biosynthesis protein
IMZ18_21160	COG0489	protein tyrosine kinase activity
IMZ18_21165	COG4464	protein tyrosine phosphatase activity
IMZ18_21170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMZ18_21195	COG5444	nuclease activity
IMZ18_21225	COG0583	DNA-binding transcription factor activity
IMZ18_21230	COG0655	NAD(P)H dehydrogenase (quinone) activity
IMZ18_21240	COG2059	Chromate
IMZ18_21245	COG2059	Chromate
IMZ18_21250	COG1522	sequence-specific DNA binding
IMZ18_21255	COG0405	Gamma-glutamyltransferase
IMZ18_21265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMZ18_21275	COG5337	Spore coat protein CotH
IMZ18_21290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IMZ18_21295	COG0583	DNA-binding transcription factor activity
IMZ18_21300	COG0028	Belongs to the TPP enzyme family
IMZ18_21305	COG3527	Alpha-acetolactate decarboxylase
IMZ18_21315	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMZ18_21330	COG3103	Sh3 type 3 domain protein
IMZ18_21335	COG1879	ABC-type sugar transport system periplasmic component
IMZ18_21340	COG1172	Belongs to the binding-protein-dependent transport system permease family
IMZ18_21345	COG1129	ABC transporter
IMZ18_21350	COG1869	D-ribose catabolic process
IMZ18_21355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMZ18_21360	COG1609	Transcriptional regulator
IMZ18_21365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMZ18_21375	COG2843	Capsule synthesis protein
IMZ18_21385	COG0791	NLP P60 protein
IMZ18_21390	COG0561	phosphatase activity
IMZ18_21395	COG1316	TRANSCRIPTIONal
IMZ18_21410	COG0814	amino acid
IMZ18_21415	COG0697	spore germination
IMZ18_21420	COG1482	cell wall glycoprotein biosynthetic process
IMZ18_21425	COG4193	domain, Protein
IMZ18_21430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ18_21435	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IMZ18_21440	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IMZ18_21445	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ18_21450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IMZ18_21450	COG0463	Glycosyl transferase, family 2
IMZ18_21465	COG1682	transport, permease protein
IMZ18_21470	COG1134	teichoic acid transport
IMZ18_21480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMZ18_21485	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMZ18_21505	COG2247	cell wall binding repeat
IMZ18_21505	COG2385	sporulation resulting in formation of a cellular spore
IMZ18_21510	COG2247	cell wall binding repeat
IMZ18_21510	COG0860	N-Acetylmuramoyl-L-alanine amidase
IMZ18_21525	COG2244	polysaccharide biosynthetic process
IMZ18_21530	COG0438	transferase activity, transferring glycosyl groups
IMZ18_21530	COG0297	glycogen (starch) synthase activity
IMZ18_21535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IMZ18_21540	COG3307	-O-antigen
IMZ18_21545	COG3206	protein involved in exopolysaccharide biosynthesis
IMZ18_21550	COG1215	transferase activity, transferring glycosyl groups
IMZ18_21555	COG0438	transferase activity, transferring glycosyl groups
IMZ18_21560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMZ18_21570	COG1131	(ABC) transporter
IMZ18_21600	COG1316	TRANSCRIPTIONal
IMZ18_21605	COG1739	Uncharacterized protein family UPF0029
IMZ18_21610	COG4585	Histidine kinase
IMZ18_21615	COG2197	response regulator
IMZ18_21620	COG1307	EDD domain protein, DegV family
IMZ18_21625	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IMZ18_21635	COG1040	competence protein
IMZ18_21645	COG2747	anti-sigma28 factor FlgM
IMZ18_21650	COG3418	PFAM FlgN family protein
IMZ18_21655	COG4786	Flagellar basal body rod
IMZ18_21655	COG1256	bacterial-type flagellum assembly
IMZ18_21660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMZ18_21670	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IMZ18_21675	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IMZ18_21680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMZ18_21685	COG1334	flagellar protein FlaG
IMZ18_21690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IMZ18_21695	COG1516	flagellar protein fliS
IMZ18_21710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IMZ18_21715	COG0653	protein targeting
IMZ18_21725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMZ18_21730	COG2010	Cytochrome c
IMZ18_21735	COG2884	Cell division ATP-binding protein ftsE
IMZ18_21740	COG2177	Part of the ABC transporter FtsEX involved in
IMZ18_21745	COG0793	Belongs to the peptidase S41A family
IMZ18_21745	COG3409	Peptidoglycan-binding domain 1 protein
IMZ18_21755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMZ18_21760	COG2814	Major facilitator Superfamily
IMZ18_21765	COG1309	transcriptional regulator
IMZ18_21770	COG3848	Pyruvate phosphate dikinase
IMZ18_21770	COG0574	Belongs to the PEP-utilizing enzyme family
IMZ18_21775	COG4897	Protein conserved in bacteria
IMZ18_21780	COG0556	nucleotide-excision repair
IMZ18_21785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMZ18_21790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IMZ18_21805	COG3595	metallopeptidase activity
IMZ18_21810	COG1983	PspC domain protein
IMZ18_21815	COG1950	PFAM Membrane protein of
IMZ18_21825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IMZ18_21830	COG2188	Transcriptional regulator
IMZ18_21835	COG0363	glucosamine-6-phosphate deaminase activity
IMZ18_21840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IMZ18_21845	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IMZ18_21850	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMZ18_21855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IMZ18_21860	COG0546	phosphoglycolate phosphatase activity
IMZ18_21875	COG5297	Belongs to the glycosyl hydrolase family 6
IMZ18_21880	COG4990	cell redox homeostasis
IMZ18_21885	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMZ18_21890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMZ18_21895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMZ18_21900	COG0131	Imidazoleglycerol-phosphate dehydratase
IMZ18_21905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IMZ18_21910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMZ18_21915	COG0107	imidazoleglycerol-phosphate synthase activity
IMZ18_21920	COG0140	phosphoribosyl-ATP diphosphatase activity
IMZ18_21920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMZ18_21940	COG1132	(ABC) transporter
IMZ18_21945	COG0457	Tetratricopeptide repeat
IMZ18_21950	COG0791	NLP P60 protein
IMZ18_21950	COG3883	PFAM NLP P60 protein
IMZ18_21955	COG0492	ferredoxin-NADP+ reductase activity
IMZ18_21960	COG1051	belongs to the nudix hydrolase family
IMZ18_21965	COG1660	Displays ATPase and GTPase activities
IMZ18_22020	COG0457	Tetratricopeptide repeat
IMZ18_22065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMZ18_22140	COG1525	nuclease
IMZ18_22155	COG1793	dna ligase
IMZ18_22185	COG0582	viral genome integration into host DNA
IMZ18_22200	COG0629	single-stranded DNA binding
IMZ18_22260	COG0791	NLP P60 protein
IMZ18_22260	COG3883	PFAM NLP P60 protein