locus-tag	class	description
KHRBS_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHRBS_00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KHRBS_00015	COG0594	ribonuclease P activity
KHRBS_00030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHRBS_00035	COG0445	tRNA wobble uridine modification
KHRBS_00040	COG0357	Ribosomal RNA small subunit methyltransferase G
KHRBS_00045	COG1475	DNA binding
KHRBS_00055	COG1192	Involved in chromosome partitioning
KHRBS_00060	COG1475	DNA binding
KHRBS_00070	COG3949	Membrane
KHRBS_00075	COG4481	Protein conserved in bacteria
KHRBS_00080	COG0243	molybdopterin cofactor binding
KHRBS_00085	COG0012	GTP binding
KHRBS_00090	COG0360	Binds together with S18 to 16S ribosomal RNA
KHRBS_00095	COG0629	single-stranded DNA binding
KHRBS_00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHRBS_00105	COG0708	Exodeoxyribonuclease III
KHRBS_00110	COG1609	Transcriptional regulator
KHRBS_00115	COG0346	lactoylglutathione lyase activity
KHRBS_00120	COG0110	maltose O-acetyltransferase activity
KHRBS_00125	COG0477	Major facilitator Superfamily
KHRBS_00125	COG2814	Major facilitator Superfamily
KHRBS_00130	COG1266	CAAX protease self-immunity
KHRBS_00135	COG1331	Highly conserved protein containing a thioredoxin domain
KHRBS_00140	COG0697	spore germination
KHRBS_00160	COG1331	Highly conserved protein containing a thioredoxin domain
KHRBS_00165	COG2814	Major facilitator Superfamily
KHRBS_00170	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHRBS_00175	COG2315	Protein conserved in bacteria
KHRBS_00180	COG0456	acetyltransferase
KHRBS_00185	COG2364	Membrane
KHRBS_00190	COG2153	protein acetylation
KHRBS_00195	COG1846	Transcriptional regulator
KHRBS_00200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_00210	COG2153	protein acetylation
KHRBS_00215	COG0583	DNA-binding transcription factor activity
KHRBS_00220	COG2814	Major facilitator Superfamily
KHRBS_00225	COG1357	PFAM Pentapeptide repeats (8 copies)
KHRBS_00230	COG4319	ketosteroid isomerase
KHRBS_00245	COG2271	Major facilitator Superfamily
KHRBS_00255	COG1227	inorganic diphosphatase activity
KHRBS_00260	COG1733	regulation of RNA biosynthetic process
KHRBS_00265	COG5577	PFAM Coat F domain
KHRBS_00275	COG4241	membrane
KHRBS_00285	COG0359	binds to the 23S rRNA
KHRBS_00290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHRBS_00295	COG2807	transmembrane transport
KHRBS_00300	COG3093	addiction module antidote protein HigA
KHRBS_00320	COG0305	Participates in initiation and elongation during chromosome replication
KHRBS_00325	COG0346	lactoylglutathione lyase activity
KHRBS_00355	COG0745	RESPONSE REGULATOR receiver
KHRBS_00360	COG5002	protein histidine kinase activity
KHRBS_00365	COG4863	YycH protein
KHRBS_00375	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHRBS_00380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHRBS_00410	COG3829	transcription factor binding
KHRBS_00415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHRBS_00420	COG0833	amino acid
KHRBS_00425	COG0010	Belongs to the arginase family
KHRBS_00440	COG0456	acetyltransferase
KHRBS_00445	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KHRBS_00465	COG1063	alcohol dehydrogenase
KHRBS_00475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHRBS_00515	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KHRBS_00525	COG2188	Transcriptional regulator
KHRBS_00530	COG2190	(PTS) system
KHRBS_00535	COG2723	6-phospho-beta-galactosidase activity
KHRBS_00545	COG3634	alkyl hydroperoxide reductase activity
KHRBS_00550	COG0450	alkyl hydroperoxide reductase
KHRBS_00555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHRBS_00560	COG2610	gluconate transmembrane transporter activity
KHRBS_00565	COG1070	Carbohydrate kinase
KHRBS_00570	COG1802	Transcriptional regulator
KHRBS_00575	COG1929	Belongs to the glycerate kinase type-1 family
KHRBS_00585	COG1346	cytolysis
KHRBS_00590	COG1380	Effector of murein hydrolase LrgA
KHRBS_00595	COG1846	Transcriptional regulator
KHRBS_00600	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_00605	COG1309	transcriptional regulator
KHRBS_00610	COG1917	Cupin 2, conserved barrel domain protein
KHRBS_00615	COG2311	Membrane
KHRBS_00620	COG1714	RDD family
KHRBS_00630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHRBS_00645	COG1309	transcriptional regulator
KHRBS_00650	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_00660	COG0326	Molecular chaperone. Has ATPase activity
KHRBS_00665	COG2814	Major facilitator Superfamily
KHRBS_00680	COG0667	Aldo Keto reductase
KHRBS_00685	COG1349	DNA-binding transcription factor activity
KHRBS_00690	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_00700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHRBS_00710	COG1082	Xylose isomerase domain protein TIM barrel
KHRBS_00715	COG2814	Major facilitator Superfamily
KHRBS_00720	COG0673	inositol 2-dehydrogenase activity
KHRBS_00725	COG1082	Xylose isomerase domain protein TIM barrel
KHRBS_00730	COG1082	Xylose isomerase domain protein TIM barrel
KHRBS_00735	COG0191	fructose-bisphosphate aldolase activity
KHRBS_00740	COG0745	RESPONSE REGULATOR receiver
KHRBS_00745	COG2205	protein histidine kinase activity
KHRBS_00750	COG1136	(ABC) transporter
KHRBS_00755	COG0577	efflux transmembrane transporter activity
KHRBS_00760	COG5294	Protein conserved in bacteria
KHRBS_00765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHRBS_00795	COG0561	phosphatase activity
KHRBS_00800	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KHRBS_00820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHRBS_00825	COG0765	amino acid transport
KHRBS_00830	COG1126	abc transporter atp-binding protein
KHRBS_00840	COG2079	MmgE PrpD family protein
KHRBS_00845	COG3192	ethanolamine utilization protein
KHRBS_00855	COG2390	Transcriptional regulator
KHRBS_00860	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHRBS_00865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHRBS_00870	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHRBS_00890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KHRBS_00895	COG2986	histidine ammonia-lyase
KHRBS_00905	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHRBS_00905	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHRBS_00925	COG3507	Belongs to the glycosyl hydrolase 43 family
KHRBS_00940	COG5444	nuclease activity
KHRBS_00955	COG1263	PTS System
KHRBS_00955	COG2190	(PTS) system
KHRBS_00955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_00960	COG2723	6-phospho-beta-galactosidase activity
KHRBS_00965	COG0589	response to stress
KHRBS_00980	COG0697	spore germination
KHRBS_01020	COG3401	FG-GAP repeat protein
KHRBS_01020	COG2755	lipolytic protein G-D-S-L family
KHRBS_01030	COG2270	Major facilitator Superfamily
KHRBS_01040	COG3711	transcriptional antiterminator
KHRBS_01045	COG2273	Hydrolase Family 16
KHRBS_01050	COG2851	Citrate transporter
KHRBS_01055	COG0753	catalase activity
KHRBS_01055	COG0693	protein deglycase activity
KHRBS_01070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHRBS_01075	COG0500	methyltransferase
KHRBS_01085	COG2610	gluconate transmembrane transporter activity
KHRBS_01090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHRBS_01095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KHRBS_01100	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_01105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHRBS_01110	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHRBS_01115	COG4894	glucomannan catabolic process
KHRBS_01130	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHRBS_01135	COG2197	response regulator
KHRBS_01140	COG4585	Histidine kinase
KHRBS_01150	COG0583	DNA-binding transcription factor activity
KHRBS_01155	COG1881	PFAM PEBP family protein
KHRBS_01160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHRBS_01170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHRBS_01175	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_01180	COG2508	Transcriptional regulator
KHRBS_01200	COG0501	Belongs to the peptidase M48B family
KHRBS_01205	COG3493	citrate carrier protein
KHRBS_01215	COG1294	oxidase, subunit
KHRBS_01220	COG4988	ABC transporter
KHRBS_01235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHRBS_01240	COG1595	DNA-templated transcription, initiation
KHRBS_01260	COG1131	(ABC) transporter
KHRBS_01265	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHRBS_01275	COG0753	catalase activity
KHRBS_01280	COG2094	Belongs to the DNA glycosylase MPG family
KHRBS_01290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_01290	COG3711	transcriptional antiterminator
KHRBS_01295	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHRBS_01300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHRBS_01305	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHRBS_01310	COG1486	melibiose metabolic process
KHRBS_01315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHRBS_01320	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KHRBS_01325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHRBS_01330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHRBS_01335	COG1696	Membrane protein involved in D-alanine export
KHRBS_01340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_01355	COG1575	Belongs to the MenA family. Type 1 subfamily
KHRBS_01360	COG2357	RelA SpoT domain protein
KHRBS_01365	COG2814	Major facilitator Superfamily
KHRBS_01385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHRBS_01390	COG1846	Transcriptional regulator
KHRBS_01395	COG5522	Integral membrane protein (intg_mem_TP0381)
KHRBS_01405	COG3711	transcriptional antiterminator
KHRBS_01410	COG1263	PTS System
KHRBS_01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_01420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHRBS_01425	COG0346	lactoylglutathione lyase activity
KHRBS_01430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHRBS_01435	COG4895	conserved protein (DUF2196)
KHRBS_01440	COG2814	Major facilitator Superfamily
KHRBS_01445	COG1346	cytolysis
KHRBS_01450	COG1380	Effector of murein hydrolase LrgA
KHRBS_01455	COG0583	DNA-binding transcription factor activity
KHRBS_01460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHRBS_01465	COG0352	thiamine-phosphate diphosphorylase activity
KHRBS_01470	COG0672	)-iron permease
KHRBS_01475	COG2822	iron ion transport
KHRBS_01480	COG2837	iron assimilation
KHRBS_01485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KHRBS_01490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHRBS_01495	COG3162	membrane
KHRBS_01505	COG1309	transcriptional regulator
KHRBS_01510	COG2246	polysaccharide biosynthetic process
KHRBS_01520	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KHRBS_01525	COG2261	transglycosylase associated protein
KHRBS_01530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHRBS_01535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHRBS_01545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KHRBS_01555	COG0772	Belongs to the SEDS family
KHRBS_01560	COG0778	Nitroreductase
KHRBS_01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHRBS_01585	COG2116	formate transmembrane transporter activity
KHRBS_01590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_01590	COG1263	PTS System
KHRBS_01605	COG0351	phosphomethylpyrimidine kinase
KHRBS_01610	COG1695	Transcriptional regulator
KHRBS_01625	COG1216	Glycosyl transferase, family 2
KHRBS_01630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHRBS_01635	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_01645	COG2233	PERMEase
KHRBS_01650	COG2363	Small membrane protein
KHRBS_01665	COG0463	Glycosyl transferase, family 2
KHRBS_01670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHRBS_01680	COG0456	acetyltransferase
KHRBS_01685	COG2089	acid synthase
KHRBS_01690	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KHRBS_01700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHRBS_01705	COG1088	dTDP-glucose 4,6-dehydratase activity
KHRBS_01710	COG1091	dTDP-4-dehydrorhamnose reductase activity
KHRBS_01715	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KHRBS_01725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHRBS_01730	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_01740	COG0833	amino acid
KHRBS_01745	COG2814	Major facilitator Superfamily
KHRBS_01750	COG0077	Prephenate dehydratase
KHRBS_01755	COG1917	Cupin 2, conserved barrel domain protein
KHRBS_01760	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_01770	COG2814	Major facilitator Superfamily
KHRBS_01775	COG0436	Aminotransferase
KHRBS_01780	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_01790	COG0280	phosphate acetyltransferase
KHRBS_01795	COG0583	DNA-binding transcription factor activity
KHRBS_01800	COG0095	Lipoate-protein ligase
KHRBS_01805	COG0697	spore germination
KHRBS_01815	COG4844	belongs to the
KHRBS_01820	COG1078	dGTPase activity
KHRBS_01825	COG3465	dGTPase activity
KHRBS_01830	COG1959	2 iron, 2 sulfur cluster binding
KHRBS_01835	COG0477	Major facilitator Superfamily
KHRBS_01845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHRBS_01850	COG1846	Transcriptional regulator
KHRBS_01855	COG1942	4-Oxalocrotonate Tautomerase
KHRBS_01860	COG1994	Peptidase M50
KHRBS_01875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHRBS_01885	COG0010	Belongs to the arginase family
KHRBS_01910	COG3391	amine dehydrogenase activity
KHRBS_01925	COG0612	Peptidase, M16
KHRBS_01930	COG0612	Peptidase, M16
KHRBS_01935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHRBS_01940	COG1131	(ABC) transporter
KHRBS_01950	COG0535	radical SAM domain protein
KHRBS_01960	COG4506	Protein conserved in bacteria
KHRBS_01965	COG0018	arginyl-trna synthetase
KHRBS_01970	COG2223	nitrite transmembrane transporter activity
KHRBS_01975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHRBS_01985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHRBS_01990	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHRBS_01995	COG1140	nitrate reductase beta subunit
KHRBS_02000	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KHRBS_02005	COG2181	nitrate reductase activity
KHRBS_02015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHRBS_02020	COG1132	(ABC) transporter
KHRBS_02025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHRBS_02035	COG4294	response to UV
KHRBS_02040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHRBS_02045	COG0247	lactate metabolic process
KHRBS_02045	COG2181	nitrate reductase activity
KHRBS_02050	COG1960	acyl-CoA dehydrogenase activity
KHRBS_02055	COG3343	RNA polymerase activity
KHRBS_02065	COG4821	SIS domain
KHRBS_02070	COG2204	response regulator
KHRBS_02075	COG0191	fructose-bisphosphate aldolase activity
KHRBS_02080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHRBS_02085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHRBS_02115	COG0281	malic enzyme
KHRBS_02120	COG0679	Auxin Efflux Carrier
KHRBS_02125	COG0789	Transcriptional regulator
KHRBS_02130	COG0346	lactoylglutathione lyase activity
KHRBS_02135	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHRBS_02140	COG2890	protein-(glutamine-N5) methyltransferase activity
KHRBS_02160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KHRBS_02165	COG0009	L-threonylcarbamoyladenylate synthase
KHRBS_02170	COG1971	Probably functions as a manganese efflux pump
KHRBS_02175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHRBS_02180	COG0698	ribose 5-phosphate isomerase
KHRBS_02185	COG4475	Protein of unknown function (DUF436)
KHRBS_02190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHRBS_02195	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHRBS_02205	COG0356	it plays a direct role in the translocation of protons across the membrane
KHRBS_02210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHRBS_02220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHRBS_02225	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHRBS_02230	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHRBS_02235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHRBS_02240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHRBS_02245	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHRBS_02255	COG4836	Membrane
KHRBS_02265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHRBS_02270	COG2385	sporulation resulting in formation of a cellular spore
KHRBS_02275	COG2304	oxidoreductase activity
KHRBS_02285	COG2304	oxidoreductase activity
KHRBS_02295	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KHRBS_02300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KHRBS_02305	COG0457	Tetratricopeptide repeat
KHRBS_02310	COG1994	Peptidase M50
KHRBS_02315	COG3237	CsbD-like
KHRBS_02330	COG0831	urea catabolic process
KHRBS_02335	COG0832	Belongs to the urease beta subunit family
KHRBS_02345	COG1959	2 iron, 2 sulfur cluster binding
KHRBS_02350	COG2910	NAD(P)H-binding
KHRBS_02360	COG0789	Transcriptional regulator
KHRBS_02365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHRBS_02385	COG1247	-acetyltransferase
KHRBS_02390	COG0739	heme binding
KHRBS_02415	COG0671	phosphoesterase, PA-phosphatase related
KHRBS_02420	COG0347	Belongs to the P(II) protein family
KHRBS_02425	COG0004	ammonium transporteR
KHRBS_02435	COG1335	isochorismatase
KHRBS_02440	COG0477	Major facilitator Superfamily
KHRBS_02445	COG1953	Uracil, thiamine, allantoin
KHRBS_02450	COG3420	alginic acid biosynthetic process
KHRBS_02455	COG2814	Major facilitator Superfamily
KHRBS_02460	COG1846	Transcriptional regulator
KHRBS_02465	COG1609	Transcriptional regulator
KHRBS_02470	COG1077	Cell shape determining protein MreB Mrl
KHRBS_02475	COG4786	Flagellar basal body rod
KHRBS_02480	COG4786	Flagellar basal body rod
KHRBS_02490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHRBS_02495	COG1970	mechanosensitive ion channel activity
KHRBS_02500	COG2972	Histidine kinase
KHRBS_02500	COG0745	RESPONSE REGULATOR receiver
KHRBS_02505	COG3764	Sortase (surface protein transpeptidase)
KHRBS_02520	COG0629	single-stranded DNA binding
KHRBS_02525	COG1349	DNA-binding transcription factor activity
KHRBS_02530	COG0561	phosphatase activity
KHRBS_02535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHRBS_02550	COG3944	biosynthesis protein
KHRBS_02560	COG4464	protein tyrosine phosphatase activity
KHRBS_02565	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHRBS_02570	COG3878	Protein conserved in bacteria
KHRBS_02585	COG5444	nuclease activity
KHRBS_02615	COG0583	DNA-binding transcription factor activity
KHRBS_02620	COG0655	NAD(P)H dehydrogenase (quinone) activity
KHRBS_02630	COG2059	Chromate
KHRBS_02635	COG2059	Chromate
KHRBS_02640	COG1522	sequence-specific DNA binding
KHRBS_02645	COG0405	Gamma-glutamyltransferase
KHRBS_02655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHRBS_02665	COG5337	Spore coat protein CotH
KHRBS_02685	COG0583	DNA-binding transcription factor activity
KHRBS_02690	COG0028	Belongs to the TPP enzyme family
KHRBS_02695	COG3527	Alpha-acetolactate decarboxylase
KHRBS_02700	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHRBS_02710	COG3103	Sh3 type 3 domain protein
KHRBS_02715	COG1879	ABC-type sugar transport system periplasmic component
KHRBS_02720	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHRBS_02725	COG1129	ABC transporter
KHRBS_02730	COG1869	D-ribose catabolic process
KHRBS_02735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHRBS_02745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHRBS_02755	COG2843	Capsule synthesis protein
KHRBS_02765	COG0791	NLP P60 protein
KHRBS_02770	COG0561	phosphatase activity
KHRBS_02775	COG1316	TRANSCRIPTIONal
KHRBS_02780	COG2814	Major facilitator Superfamily
KHRBS_02790	COG0814	amino acid
KHRBS_02805	COG1482	cell wall glycoprotein biosynthetic process
KHRBS_02810	COG4193	domain, Protein
KHRBS_02865	COG1682	transport, permease protein
KHRBS_02875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHRBS_02895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KHRBS_02900	COG1316	TRANSCRIPTIONal
KHRBS_02930	COG2244	polysaccharide biosynthetic process
KHRBS_02935	COG0297	glycogen (starch) synthase activity
KHRBS_02935	COG0438	transferase activity, transferring glycosyl groups
KHRBS_02940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHRBS_02945	COG3307	-O-antigen
KHRBS_02950	COG3206	protein involved in exopolysaccharide biosynthesis
KHRBS_02955	COG1215	transferase activity, transferring glycosyl groups
KHRBS_02960	COG0438	transferase activity, transferring glycosyl groups
KHRBS_02975	COG1739	Uncharacterized protein family UPF0029
KHRBS_02980	COG4585	Histidine kinase
KHRBS_02985	COG2197	response regulator
KHRBS_02990	COG1307	EDD domain protein, DegV family
KHRBS_02995	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KHRBS_03005	COG1040	competence protein
KHRBS_03015	COG2747	anti-sigma28 factor FlgM
KHRBS_03020	COG3418	PFAM FlgN family protein
KHRBS_03025	COG1256	bacterial-type flagellum assembly
KHRBS_03025	COG4786	Flagellar basal body rod
KHRBS_03030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHRBS_03040	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KHRBS_03045	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KHRBS_03050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHRBS_03055	COG1334	flagellar protein FlaG
KHRBS_03060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KHRBS_03065	COG1516	flagellar protein fliS
KHRBS_03080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHRBS_03090	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHRBS_03095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHRBS_03100	COG2010	Cytochrome c
KHRBS_03105	COG2884	Cell division ATP-binding protein ftsE
KHRBS_03110	COG2177	Part of the ABC transporter FtsEX involved in
KHRBS_03115	COG0793	Belongs to the peptidase S41A family
KHRBS_03115	COG3409	Peptidoglycan-binding domain 1 protein
KHRBS_03125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHRBS_03130	COG2814	Major facilitator Superfamily
KHRBS_03135	COG1309	transcriptional regulator
KHRBS_03140	COG0574	Belongs to the PEP-utilizing enzyme family
KHRBS_03140	COG3848	Pyruvate phosphate dikinase
KHRBS_03145	COG4897	Protein conserved in bacteria
KHRBS_03150	COG0556	nucleotide-excision repair
KHRBS_03155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHRBS_03160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHRBS_03175	COG3595	metallopeptidase activity
KHRBS_03180	COG1983	PspC domain protein
KHRBS_03185	COG1950	PFAM Membrane protein of
KHRBS_03190	COG2814	Major facilitator Superfamily
KHRBS_03195	COG1846	Transcriptional regulator
KHRBS_03205	COG2124	cytochrome p450
KHRBS_03210	COG1846	Transcriptional regulator
KHRBS_03215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KHRBS_03225	COG0363	glucosamine-6-phosphate deaminase activity
KHRBS_03230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHRBS_03235	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHRBS_03240	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHRBS_03245	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KHRBS_03250	COG0546	phosphoglycolate phosphatase activity
KHRBS_03255	COG0110	maltose O-acetyltransferase activity
KHRBS_03260	COG5297	Belongs to the glycosyl hydrolase family 6
KHRBS_03265	COG4990	cell redox homeostasis
KHRBS_03270	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KHRBS_03275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KHRBS_03280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHRBS_03285	COG0131	Imidazoleglycerol-phosphate dehydratase
KHRBS_03290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHRBS_03295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KHRBS_03300	COG0107	imidazoleglycerol-phosphate synthase activity
KHRBS_03305	COG0140	phosphoribosyl-ATP diphosphatase activity
KHRBS_03305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHRBS_03330	COG1132	(ABC) transporter
KHRBS_03335	COG0457	Tetratricopeptide repeat
KHRBS_03340	COG3883	PFAM NLP P60 protein
KHRBS_03340	COG0791	NLP P60 protein
KHRBS_03345	COG0492	ferredoxin-NADP+ reductase activity
KHRBS_03350	COG1051	belongs to the nudix hydrolase family
KHRBS_03360	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KHRBS_03370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_03385	COG0745	RESPONSE REGULATOR receiver
KHRBS_03390	COG5002	protein histidine kinase activity
KHRBS_03395	COG1136	(ABC) transporter
KHRBS_03400	COG0577	efflux transmembrane transporter activity
KHRBS_03405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHRBS_03410	COG0288	reversible hydration of carbon dioxide
KHRBS_03415	COG0659	secondary active sulfate transmembrane transporter activity
KHRBS_03420	COG1694	Mazg nucleotide pyrophosphohydrolase
KHRBS_03425	COG1611	Belongs to the LOG family
KHRBS_03430	COG1609	Transcriptional regulator
KHRBS_03435	COG0366	Alpha amylase catalytic
KHRBS_03440	COG2182	Extracellular solute-binding protein
KHRBS_03445	COG1175	transmembrane transport
KHRBS_03450	COG3833	ABC-type maltose transport systems, permease component
KHRBS_03455	COG5521	maltodextrose utilization protein MalA
KHRBS_03460	COG1554	hydrolase, family 65, central catalytic
KHRBS_03465	COG0366	Alpha amylase catalytic
KHRBS_03470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHRBS_03475	COG0740	serine-type endopeptidase activity
KHRBS_03485	COG3621	Patatin-like phospholipase
KHRBS_03490	COG0277	FAD linked oxidase domain protein
KHRBS_03500	COG2076	Multidrug Resistance protein
KHRBS_03505	COG2076	Multidrug Resistance protein
KHRBS_03510	COG1309	transcriptional regulator
KHRBS_03515	COG0531	amino acid
KHRBS_03520	COG1621	beta-fructofuranosidase activity
KHRBS_03525	COG1621	beta-fructofuranosidase activity
KHRBS_03530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHRBS_03535	COG1794	racemase activity, acting on amino acids and derivatives
KHRBS_03545	COG3479	Phenolic acid decarboxylase
KHRBS_03555	COG2272	Belongs to the type-B carboxylesterase lipase family
KHRBS_03560	COG1396	sequence-specific DNA binding
KHRBS_03565	COG3944	biosynthesis protein
KHRBS_03570	COG0489	protein tyrosine kinase activity
KHRBS_03575	COG1086	Polysaccharide biosynthesis protein
KHRBS_03580	COG0438	transferase activity, transferring glycosyl groups
KHRBS_03585	COG1215	transferase activity, transferring glycosyl groups
KHRBS_03590	COG0438	transferase activity, transferring glycosyl groups
KHRBS_03600	COG1216	Glycosyl transferase, family 2
KHRBS_03605	COG5039	Polysaccharide pyruvyl transferase
KHRBS_03620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KHRBS_03625	COG0110	maltose O-acetyltransferase activity
KHRBS_03630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHRBS_03635	COG5039	Polysaccharide pyruvyl transferase
KHRBS_03645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KHRBS_03650	COG1620	l-lactate permease
KHRBS_03660	COG1609	Transcriptional regulator
KHRBS_03665	COG2182	Extracellular solute-binding protein
KHRBS_03670	COG1175	transmembrane transport
KHRBS_03675	COG3833	ABC-type maltose transport systems, permease component
KHRBS_03680	COG1874	Beta-galactosidase
KHRBS_03685	COG3867	Arabinogalactan endo-beta-1,4-galactanase
KHRBS_03690	COG2208	phosphoserine phosphatase activity
KHRBS_03695	COG0596	Alpha beta hydrolase
KHRBS_03700	COG1131	(ABC) transporter
KHRBS_03705	COG0842	Transport permease protein
KHRBS_03710	COG4585	Histidine kinase
KHRBS_03715	COG2197	response regulator
KHRBS_03720	COG0247	lactate metabolic process
KHRBS_03725	COG1139	Iron-sulfur cluster binding protein
KHRBS_03730	COG1556	Lactate utilization protein
KHRBS_03735	COG3858	chitin binding
KHRBS_03740	COG1113	amino acid transport
KHRBS_03745	COG0697	spore germination
KHRBS_03750	COG0583	DNA-binding transcription factor activity
KHRBS_03755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHRBS_03760	COG1609	Transcriptional regulator
KHRBS_03765	COG2814	Major facilitator Superfamily
KHRBS_03770	COG2390	Transcriptional regulator
KHRBS_03775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHRBS_03785	COG0126	phosphoglycerate kinase activity
KHRBS_03790	COG0149	triose-phosphate isomerase activity
KHRBS_03795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHRBS_03800	COG0148	phosphopyruvate hydratase activity
KHRBS_03805	COG0456	acetyltransferase
KHRBS_03810	COG4640	response to antibiotic
KHRBS_03815	COG3064	Membrane
KHRBS_03825	COG2095	MarC family integral membrane protein
KHRBS_03830	COG1510	regulation of RNA biosynthetic process
KHRBS_03835	COG0517	IMP dehydrogenase activity
KHRBS_03835	COG1125	glycine betaine transport
KHRBS_03840	COG1174	glycine betaine transport
KHRBS_03845	COG1732	Glycine betaine
KHRBS_03850	COG1174	glycine betaine transport
KHRBS_03855	COG0640	Transcriptional regulator
KHRBS_03860	COG5658	integral membrane protein
KHRBS_03880	COG1510	regulation of RNA biosynthetic process
KHRBS_03890	COG1174	glycine betaine transport
KHRBS_03895	COG1732	Glycine betaine
KHRBS_03900	COG1174	glycine betaine transport
KHRBS_03905	COG0840	transmembrane signaling receptor activity
KHRBS_03910	COG1733	regulation of RNA biosynthetic process
KHRBS_03915	COG1396	sequence-specific DNA binding
KHRBS_03920	COG1396	sequence-specific DNA binding
KHRBS_03925	COG1476	TRANSCRIPTIONal
KHRBS_03930	COG0596	Alpha beta hydrolase
KHRBS_03935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHRBS_03940	COG1647	Serine aminopeptidase, S33
KHRBS_03945	COG0557	exoribonuclease II activity
KHRBS_03950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHRBS_03965	COG1309	transcriptional regulator
KHRBS_03970	COG2076	Multidrug Resistance protein
KHRBS_03980	COG1289	transmembrane transporter activity
KHRBS_03985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHRBS_03990	COG0673	inositol 2-dehydrogenase activity
KHRBS_03995	COG1937	Protein conserved in bacteria
KHRBS_04000	COG2608	mercury ion transmembrane transporter activity
KHRBS_04005	COG2217	Heavy metal translocating P-type atpase
KHRBS_04010	COG2217	Heavy metal translocating P-type atpase
KHRBS_04015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KHRBS_04020	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KHRBS_04025	COG2860	membrane
KHRBS_04035	COG3973	AAA domain
KHRBS_04040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHRBS_04045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHRBS_04050	COG0025	NhaP-type Na H and K H
KHRBS_04060	COG0656	L-ascorbic acid biosynthetic process
KHRBS_04065	COG4149	molybdate abc transporter
KHRBS_04070	COG0725	ABC transporter, periplasmic molybdate-binding protein
KHRBS_04075	COG1910	domain protein
KHRBS_04085	COG1988	membrane-bound metal-dependent
KHRBS_04095	COG0531	amino acid
KHRBS_04100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHRBS_04105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_04110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_04115	COG1120	ATPase activity
KHRBS_04120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHRBS_04125	COG1136	(ABC) transporter
KHRBS_04130	COG0577	efflux transmembrane transporter activity
KHRBS_04140	COG2140	Oxalate decarboxylase
KHRBS_04150	COG1191	sigma factor activity
KHRBS_04160	COG0745	RESPONSE REGULATOR receiver
KHRBS_04165	COG2205	protein histidine kinase activity
KHRBS_04170	COG3386	PFAM SMP-30 Gluconolaconase
KHRBS_04175	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_04180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHRBS_04185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_04190	COG1120	ATPase activity
KHRBS_04195	COG2096	Adenosyltransferase
KHRBS_04200	COG2814	Major facilitator Superfamily
KHRBS_04205	COG4758	membrane
KHRBS_04210	COG1842	Phage shock protein A
KHRBS_04215	COG3595	metallopeptidase activity
KHRBS_04220	COG4758	membrane
KHRBS_04225	COG4585	Histidine kinase
KHRBS_04230	COG2197	response regulator
KHRBS_04240	COG0814	amino acid
KHRBS_04245	COG0697	spore germination
KHRBS_04255	COG0114	fumarate hydratase activity
KHRBS_04260	COG1309	transcriptional regulator
KHRBS_04270	COG2205	protein histidine kinase activity
KHRBS_04270	COG2770	Histidine kinase
KHRBS_04275	COG0745	RESPONSE REGULATOR receiver
KHRBS_04280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHRBS_04285	COG0783	Belongs to the Dps family
KHRBS_04290	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_04305	COG1120	ATPase activity
KHRBS_04315	COG0583	DNA-binding transcription factor activity
KHRBS_04330	COG0477	Major facilitator Superfamily
KHRBS_04340	COG5577	PFAM Coat F domain
KHRBS_04365	COG0183	Belongs to the thiolase family
KHRBS_04370	COG1960	acyl-CoA dehydrogenase activity
KHRBS_04375	COG1393	Belongs to the ArsC family
KHRBS_04380	COG0509	glycine decarboxylation via glycine cleavage system
KHRBS_04390	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHRBS_04395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_04405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHRBS_04410	COG2011	ABC-type metal ion transport system permease component
KHRBS_04415	COG1464	Belongs to the NlpA lipoprotein family
KHRBS_04420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHRBS_04430	COG0396	ATPase activity
KHRBS_04435	COG0719	Fe-S assembly protein
KHRBS_04440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHRBS_04445	COG0822	iron-sulfur transferase activity
KHRBS_04450	COG0719	Fe-S assembly protein
KHRBS_04455	COG0640	Transcriptional regulator
KHRBS_04475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHRBS_04480	COG0322	excinuclease ABC activity
KHRBS_04485	COG2222	sugar isomerase
KHRBS_04500	COG0395	ABC-type sugar transport system, permease component
KHRBS_04505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHRBS_04510	COG2188	Transcriptional regulator
KHRBS_04515	COG3842	ATPase activity
KHRBS_04520	COG2356	endonuclease I
KHRBS_04530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHRBS_04535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KHRBS_04540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KHRBS_04545	COG2068	MobA-Related Protein
KHRBS_04550	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KHRBS_04555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KHRBS_04560	COG2080	2 iron, 2 sulfur cluster binding
KHRBS_04570	COG2351	hydroxyisourate hydrolase activity
KHRBS_04575	COG3195	allantoin biosynthetic process
KHRBS_04575	COG3648	Uricase
KHRBS_04580	COG2233	PERMEase
KHRBS_04590	COG2508	Transcriptional regulator
KHRBS_04605	COG1801	Protein of unknown function DUF72
KHRBS_04610	COG0730	response to heat
KHRBS_04615	COG0737	Belongs to the 5'-nucleotidase family
KHRBS_04620	COG3377	Domain of unknown function (DUF1805)
KHRBS_04630	COG0739	heme binding
KHRBS_04635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KHRBS_04645	COG4470	Protein conserved in bacteria
KHRBS_04650	COG2445	Protein of unknown function DUF86
KHRBS_04655	COG0647	UMP catabolic process
KHRBS_04660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KHRBS_04665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHRBS_04670	COG0460	homoserine dehydrogenase
KHRBS_04675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KHRBS_04680	COG0083	homoserine kinase activity
KHRBS_04685	COG0823	Involved in the tonB-independent uptake of proteins
KHRBS_04685	COG4946	Tricorn protease homolog
KHRBS_04685	COG1506	peptidase
KHRBS_04690	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHRBS_04695	COG4837	Protein of unknown function (DUF1462)
KHRBS_04700	COG1252	NADH dehydrogenase
KHRBS_04705	COG4844	belongs to the
KHRBS_04710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHRBS_04715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHRBS_04720	COG0316	Belongs to the HesB IscA family
KHRBS_04725	COG0456	acetyltransferase
KHRBS_04730	COG2808	Putative FMN-binding domain
KHRBS_04735	COG0516	GMP reductase activity
KHRBS_04745	COG0492	ferredoxin-NADP+ reductase activity
KHRBS_04750	COG1252	NADH dehydrogenase
KHRBS_04765	COG3584	3D domain protein
KHRBS_04775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHRBS_04780	COG2056	Na+-H+ antiporter family
KHRBS_04785	COG1268	BioY protein
KHRBS_04790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHRBS_04795	COG2819	hydrolase of the alpha beta superfamily
KHRBS_04800	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_04805	COG1169	isochorismate synthase
KHRBS_04815	COG1535	isochorismatase
KHRBS_04815	COG3433	isochorismatase activity
KHRBS_04825	COG3251	PFAM MbtH domain protein
KHRBS_04830	COG5634	Uncharacterized conserved protein (DUF2278)
KHRBS_04835	COG0686	Belongs to the AlaDH PNT family
KHRBS_04840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KHRBS_04840	COG2508	Transcriptional regulator
KHRBS_04845	COG4842	Belongs to the WXG100 family
KHRBS_04850	COG5417	Belongs to the EsaB family
KHRBS_04855	COG4499	WXG100 protein secretion system (Wss), protein YukC
KHRBS_04860	COG0433	COG0433 Predicted ATPase
KHRBS_04860	COG1674	ftsk spoiiie
KHRBS_04865	COG1511	domain protein
KHRBS_04875	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_04880	COG1418	mRNA catabolic process
KHRBS_04895	COG0628	permease
KHRBS_04910	COG5506	Protein of unknown function (DUF1694)
KHRBS_04915	COG1335	isochorismatase
KHRBS_04920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHRBS_04925	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KHRBS_04940	COG0142	geranyltranstransferase activity
KHRBS_04955	COG2197	response regulator
KHRBS_04960	COG2050	protein possibly involved in aromatic compounds catabolism
KHRBS_04965	COG1320	monovalent cation:proton antiporter activity
KHRBS_04970	COG2212	antiporter activity
KHRBS_04975	COG1863	multisubunit Na H antiporter MnhE subunit
KHRBS_04980	COG0651	ATP synthesis coupled electron transport
KHRBS_04985	COG1006	Multisubunit Na H antiporter MnhC subunit
KHRBS_04990	COG2111	Na H antiporter
KHRBS_05005	COG3493	citrate carrier protein
KHRBS_05030	COG4565	transcriptional regulatory protein
KHRBS_05045	COG3011	Protein conserved in bacteria
KHRBS_05050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHRBS_05055	COG2814	Major facilitator Superfamily
KHRBS_05065	COG5018	Exonuclease
KHRBS_05075	COG2205	protein histidine kinase activity
KHRBS_05080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KHRBS_05090	COG2267	carboxylic ester hydrolase activity
KHRBS_05095	COG1522	sequence-specific DNA binding
KHRBS_05100	COG0436	Aminotransferase
KHRBS_05105	COG1098	S1 RNA binding domain
KHRBS_05110	COG2155	Conserved Protein
KHRBS_05115	COG1979	alcohol dehydrogenase
KHRBS_05120	COG1979	alcohol dehydrogenase
KHRBS_05140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHRBS_05155	COG2738	Putative neutral zinc metallopeptidase
KHRBS_05160	COG1253	flavin adenine dinucleotide binding
KHRBS_05165	COG0366	Alpha amylase catalytic
KHRBS_05170	COG0432	Pfam Uncharacterised protein family UPF0047
KHRBS_05185	COG0840	transmembrane signaling receptor activity
KHRBS_05190	COG0840	transmembrane signaling receptor activity
KHRBS_05195	COG0840	transmembrane signaling receptor activity
KHRBS_05200	COG0840	transmembrane signaling receptor activity
KHRBS_05205	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_05205	COG3347	Dehydrogenase
KHRBS_05210	COG1349	DNA-binding transcription factor activity
KHRBS_05215	COG1070	Carbohydrate kinase
KHRBS_05220	COG3254	rhamnose metabolic process
KHRBS_05225	COG4806	L-rhamnose isomerase
KHRBS_05230	COG0673	inositol 2-dehydrogenase activity
KHRBS_05235	COG0628	permease
KHRBS_05240	COG1968	undecaprenyl-diphosphatase activity
KHRBS_05250	COG5553	Cysteine dioxygenase type I
KHRBS_05255	COG0477	Major facilitator Superfamily
KHRBS_05260	COG1705	Flagellar rod assembly protein muramidase FlgJ
KHRBS_05265	COG4682	membrane
KHRBS_05270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHRBS_05275	COG0569	domain protein
KHRBS_05285	COG1510	regulation of RNA biosynthetic process
KHRBS_05295	COG1454	alcohol dehydrogenase
KHRBS_05305	COG2318	DinB family
KHRBS_05310	COG1585	Membrane protein implicated in regulation of membrane protease activity
KHRBS_05315	COG2268	Band 7 protein
KHRBS_05320	COG1247	-acetyltransferase
KHRBS_05325	COG3859	Proton-coupled thiamine transporter YuaJ
KHRBS_05455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHRBS_05460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHRBS_05465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHRBS_05470	COG0297	glycogen (starch) synthase activity
KHRBS_05475	COG0058	SHG alpha-glucan phosphorylase activity
KHRBS_05485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHRBS_05490	COG0438	transferase activity, transferring glycosyl groups
KHRBS_05495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHRBS_05505	COG0438	transferase activity, transferring glycosyl groups
KHRBS_05510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHRBS_05515	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHRBS_05520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHRBS_05525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHRBS_05530	COG1169	isochorismate synthase
KHRBS_05535	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KHRBS_05540	COG0596	Alpha beta hydrolase
KHRBS_05545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KHRBS_05550	COG0318	PFAM AMP-dependent synthetase and ligase
KHRBS_05555	COG4948	Mandelate Racemase Muconate Lactonizing
KHRBS_05565	COG1121	(ABC) transporter
KHRBS_05570	COG1321	iron dependent repressor
KHRBS_05570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHRBS_05575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHRBS_05585	COG1294	oxidase, subunit
KHRBS_05590	COG1271	oxidase subunit
KHRBS_05595	COG0254	rRNA binding
KHRBS_05600	COG0288	reversible hydration of carbon dioxide
KHRBS_05605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KHRBS_05610	COG1854	S-ribosylhomocysteine lyase activity
KHRBS_05625	COG0783	Belongs to the Dps family
KHRBS_05630	COG4824	toxin secretion phage lysis holin
KHRBS_05635	COG0494	nUDIX hydrolase
KHRBS_05640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHRBS_05645	COG1116	anion transmembrane transporter activity
KHRBS_05650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHRBS_05655	COG1506	peptidase
KHRBS_05665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KHRBS_05670	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHRBS_05680	COG1113	amino acid transport
KHRBS_05685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KHRBS_05690	COG2267	carboxylic ester hydrolase activity
KHRBS_05700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHRBS_05705	COG1242	4 iron, 4 sulfur cluster binding
KHRBS_05720	COG1725	Transcriptional regulator
KHRBS_05725	COG1131	(ABC) transporter
KHRBS_05740	COG1136	(ABC) transporter
KHRBS_05745	COG0577	efflux transmembrane transporter activity
KHRBS_05750	COG0745	RESPONSE REGULATOR receiver
KHRBS_05755	COG2205	protein histidine kinase activity
KHRBS_05760	COG1136	(ABC) transporter
KHRBS_05765	COG0577	efflux transmembrane transporter activity
KHRBS_05775	COG2814	Major facilitator Superfamily
KHRBS_05780	COG2202	Pas domain
KHRBS_05780	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_05795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHRBS_05800	COG1486	melibiose metabolic process
KHRBS_05825	COG1073	alpha beta
KHRBS_05835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHRBS_05840	COG0156	8-amino-7-oxononanoate synthase activity
KHRBS_05850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KHRBS_05855	COG2124	cytochrome p450
KHRBS_05860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHRBS_05865	COG0395	ABC-type sugar transport system, permease component
KHRBS_05870	COG1653	transport
KHRBS_05885	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KHRBS_05900	COG5578	integral membrane protein
KHRBS_05910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KHRBS_05915	COG2081	HI0933 family
KHRBS_05920	COG2244	polysaccharide biosynthetic process
KHRBS_05925	COG1187	pseudouridine synthase activity
KHRBS_05930	COG1349	DNA-binding transcription factor activity
KHRBS_05935	COG1131	(ABC) transporter
KHRBS_05940	COG4473	ABC transporter
KHRBS_05945	COG2252	PERMEase
KHRBS_05950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHRBS_05955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHRBS_05960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KHRBS_05970	COG1597	lipid kinase activity
KHRBS_05975	COG1523	belongs to the glycosyl hydrolase 13 family
KHRBS_05980	COG0510	thiamine kinase activity
KHRBS_05990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KHRBS_05995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_06000	COG0281	malic enzyme
KHRBS_06005	COG5584	Small secreted protein
KHRBS_06010	COG1363	Peptidase, m42
KHRBS_06020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_06025	COG4848	Belongs to the UPF0354 family
KHRBS_06030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHRBS_06035	COG1674	ftsk spoiiie
KHRBS_06040	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KHRBS_06045	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHRBS_06050	COG4980	gas vesicle protein
KHRBS_06055	COG3118	belongs to the thioredoxin family
KHRBS_06060	COG1605	Chorismate mutase
KHRBS_06060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KHRBS_06065	COG1609	Transcriptional regulator
KHRBS_06075	COG1360	Flagellar Motor Protein
KHRBS_06090	COG0454	-acetyltransferase
KHRBS_06095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHRBS_06100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHRBS_06110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHRBS_06120	COG1956	GAF domain-containing protein
KHRBS_06125	COG1309	transcriptional regulator
KHRBS_06130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KHRBS_06140	COG1114	Component of the transport system for branched-chain amino acids
KHRBS_06145	COG1104	cysteine desulfurase activity
KHRBS_06160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHRBS_06165	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KHRBS_06175	COG0616	signal peptide processing
KHRBS_06180	COG1714	RDD family
KHRBS_06190	COG3874	Sporulation protein YtfJ
KHRBS_06195	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHRBS_06205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHRBS_06210	COG0521	Mo-molybdopterin cofactor biosynthetic process
KHRBS_06215	COG0137	argininosuccinate synthase activity
KHRBS_06220	COG0165	Argininosuccinate lyase
KHRBS_06230	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_06235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KHRBS_06240	COG0583	DNA-binding transcription factor activity
KHRBS_06245	COG0454	-acetyltransferase
KHRBS_06250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHRBS_06255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHRBS_06260	COG0765	amino acid transport
KHRBS_06265	COG0765	amino acid transport
KHRBS_06270	COG1126	abc transporter atp-binding protein
KHRBS_06275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHRBS_06280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KHRBS_06285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHRBS_06290	COG0196	riboflavin kinase activity
KHRBS_06295	COG1473	amidohydrolase
KHRBS_06300	COG0730	response to heat
KHRBS_06310	COG4109	DRTGG domain
KHRBS_06320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHRBS_06350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHRBS_06355	COG0825	malonyl-CoA metabolic process
KHRBS_06360	COG0205	6-phosphofructokinase activity
KHRBS_06365	COG0469	pyruvate kinase activity
KHRBS_06370	COG3030	protein affecting phage T7 exclusion by the F plasmid
KHRBS_06375	COG0628	permease
KHRBS_06385	COG0372	Belongs to the citrate synthase family
KHRBS_06390	COG0538	isocitrate dehydrogenase activity
KHRBS_06395	COG0039	L-malate dehydrogenase activity
KHRBS_06400	COG0745	RESPONSE REGULATOR receiver
KHRBS_06410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHRBS_06410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHRBS_06415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHRBS_06430	COG0237	dephospho-CoA kinase activity
KHRBS_06435	COG0656	L-ascorbic acid biosynthetic process
KHRBS_06440	COG2814	Major facilitator Superfamily
KHRBS_06445	COG1733	regulation of RNA biosynthetic process
KHRBS_06450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHRBS_06455	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KHRBS_06460	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHRBS_06465	COG3611	Membrane attachment protein
KHRBS_06470	COG1484	DNA-dependent DNA replication
KHRBS_06475	COG0398	Pfam SNARE associated Golgi protein
KHRBS_06500	COG3279	Response regulator of the LytR AlgR family
KHRBS_06505	COG1380	Effector of murein hydrolase LrgA
KHRBS_06510	COG1346	cytolysis
KHRBS_06520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHRBS_06525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KHRBS_06530	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHRBS_06535	COG3326	Membrane
KHRBS_06545	COG1363	Peptidase, m42
KHRBS_06550	COG3507	Belongs to the glycosyl hydrolase 43 family
KHRBS_06555	COG2160	L-arabinose isomerase activity
KHRBS_06560	COG1069	ribulokinase activity
KHRBS_06565	COG0235	Class ii aldolase
KHRBS_06570	COG0647	UMP catabolic process
KHRBS_06575	COG0371	Dehydrogenase
KHRBS_06580	COG1653	transport
KHRBS_06585	COG1175	transmembrane transport
KHRBS_06590	COG0395	ABC-type sugar transport system, permease component
KHRBS_06595	COG3534	alpha-L-arabinofuranosidase
KHRBS_06600	COG1966	Carbon starvation protein
KHRBS_06605	COG0346	lactoylglutathione lyase activity
KHRBS_06610	COG0247	lactate metabolic process
KHRBS_06615	COG0277	FAD linked oxidase domain protein
KHRBS_06620	COG3835	regulator
KHRBS_06630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHRBS_06640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHRBS_06650	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHRBS_06655	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KHRBS_06660	COG1286	toxin biosynthetic process
KHRBS_06665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KHRBS_06665	COG1796	DNA polymerase
KHRBS_06675	COG3766	membrane
KHRBS_06680	COG0318	PFAM AMP-dependent synthetase and ligase
KHRBS_06685	COG1309	transcriptional regulator
KHRBS_06690	COG1024	Enoyl-CoA hydratase
KHRBS_06695	COG2086	electron transfer activity
KHRBS_06700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KHRBS_06705	COG3534	alpha-L-arabinofuranosidase
KHRBS_06710	COG3118	belongs to the thioredoxin family
KHRBS_06715	COG0322	excinuclease ABC activity
KHRBS_06720	COG0527	aspartate kinase activity
KHRBS_06725	COG1719	4-vinyl reductase, 4VR
KHRBS_06735	COG2009	succinate dehydrogenase
KHRBS_06740	COG1053	succinate dehydrogenase
KHRBS_06745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KHRBS_06750	COG0824	Thioesterase
KHRBS_06755	COG2197	response regulator
KHRBS_06760	COG1846	Transcriptional regulator
KHRBS_06765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KHRBS_06770	COG5401	PFAM Sporulation and spore germination
KHRBS_06775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHRBS_06780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHRBS_06785	COG0622	Phosphoesterase
KHRBS_06795	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
KHRBS_06805	COG0454	-acetyltransferase
KHRBS_06815	COG0028	Belongs to the TPP enzyme family
KHRBS_06820	COG0440	acetolactate synthase activity
KHRBS_06825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHRBS_06830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHRBS_06835	COG0473	3-isopropylmalate dehydrogenase activity
KHRBS_06840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHRBS_06845	COG0066	3-isopropylmalate dehydratase activity
KHRBS_06850	COG1477	protein flavinylation
KHRBS_06850	COG0457	Tetratricopeptide repeat
KHRBS_06855	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHRBS_06860	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHRBS_06865	COG0470	DNA polymerase III
KHRBS_06865	COG1067	ATP-dependent peptidase activity
KHRBS_06870	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHRBS_06875	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KHRBS_06885	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KHRBS_06890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHRBS_06895	COG0181	hydroxymethylbilane synthase activity
KHRBS_06900	COG1587	Uroporphyrinogen-III synthase
KHRBS_06905	COG0113	porphobilinogen synthase activity
KHRBS_06910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KHRBS_06935	COG0285	dihydrofolate synthase activity
KHRBS_06940	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KHRBS_06950	COG0424	maF-like protein
KHRBS_06960	COG1077	Cell shape determining protein MreB Mrl
KHRBS_06965	COG1792	Involved in formation and maintenance of cell shape
KHRBS_06970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KHRBS_06975	COG0850	regulation of cytokinetic process
KHRBS_06980	COG2894	cell division
KHRBS_06990	COG1994	Peptidase M50
KHRBS_06995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KHRBS_07000	COG2868	ribosomal protein
KHRBS_07005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHRBS_07010	COG3290	protein histidine kinase activity
KHRBS_07015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHRBS_07020	COG4492	Belongs to the UPF0735 family
KHRBS_07025	COG0077	Prephenate dehydratase
KHRBS_07030	COG1827	regulation of RNA biosynthetic process
KHRBS_07035	COG1104	cysteine desulfurase activity
KHRBS_07040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KHRBS_07050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KHRBS_07055	COG1388	LysM domain
KHRBS_07065	COG0217	transcriptional regulatory protein
KHRBS_07070	COG1115	amino acid carrier protein
KHRBS_07090	COG2112	serine threonine protein kinase
KHRBS_07095	COG0673	inositol 2-dehydrogenase activity
KHRBS_07110	COG0632	four-way junction helicase activity
KHRBS_07115	COG2255	four-way junction helicase activity
KHRBS_07125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHRBS_07130	COG0343	queuine tRNA-ribosyltransferase activity
KHRBS_07135	COG1862	Preprotein translocase
KHRBS_07145	COG2323	membrane
KHRBS_07150	COG2244	polysaccharide biosynthetic process
KHRBS_07160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHRBS_07160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHRBS_07170	COG5416	Lipopolysaccharide assembly protein A domain
KHRBS_07175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KHRBS_07175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KHRBS_07180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHRBS_07185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHRBS_07190	COG1490	D-aminoacyl-tRNA deacylase activity
KHRBS_07195	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHRBS_07195	COG3103	Sh3 type 3 domain protein
KHRBS_07195	COG4991	sh3 domain protein
KHRBS_07205	COG0124	histidyl-tRNA synthetase
KHRBS_07210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHRBS_07225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHRBS_07230	COG1959	2 iron, 2 sulfur cluster binding
KHRBS_07235	COG1104	cysteine desulfurase activity
KHRBS_07240	COG0482	sulfurtransferase activity
KHRBS_07245	COG0457	Tetratricopeptide repeat
KHRBS_07250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHRBS_07255	COG3881	PFAM PRC-barrel domain
KHRBS_07275	COG0765	amino acid transport
KHRBS_07280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHRBS_07285	COG1126	abc transporter atp-binding protein
KHRBS_07290	COG0628	permease
KHRBS_07295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHRBS_07300	COG4472	Bacterial protein of unknown function (DUF965)
KHRBS_07305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHRBS_07310	COG3906	Belongs to the UPF0473 family
KHRBS_07315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHRBS_07335	COG0572	uridine kinase
KHRBS_07340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHRBS_07360	COG2226	methyltransferase
KHRBS_07365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHRBS_07370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHRBS_07375	COG0626	cystathionine gamma-synthase activity
KHRBS_07385	COG2427	Protein of unknown function (DUF1641)
KHRBS_07390	COG3383	formate dehydrogenase (NAD+) activity
KHRBS_07395	COG5609	conserved protein (DUF2294)
KHRBS_07400	COG2116	formate transmembrane transporter activity
KHRBS_07415	COG2226	methyltransferase
KHRBS_07420	COG1309	transcriptional regulator
KHRBS_07425	COG2124	cytochrome p450
KHRBS_07425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHRBS_07435	COG2755	lipolytic protein G-D-S-L family
KHRBS_07435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHRBS_07450	COG1378	Sugar-specific transcriptional regulator TrmB
KHRBS_07455	COG1280	lysine exporter protein (LysE YggA)
KHRBS_07460	COG1113	amino acid transport
KHRBS_07465	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KHRBS_07465	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KHRBS_07470	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_07475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_07490	COG1621	beta-fructofuranosidase activity
KHRBS_07495	COG0693	protein deglycase activity
KHRBS_07500	COG1064	alcohol dehydrogenase
KHRBS_07510	COG0789	Transcriptional regulator
KHRBS_07515	COG5577	PFAM Coat F domain
KHRBS_07525	COG1063	alcohol dehydrogenase
KHRBS_07530	COG5577	PFAM Coat F domain
KHRBS_07540	COG0346	lactoylglutathione lyase activity
KHRBS_07545	COG4991	sh3 domain protein
KHRBS_07550	COG4991	sh3 domain protein
KHRBS_07555	COG0596	Alpha beta hydrolase
KHRBS_07560	COG5566	PFAM Mor transcription activator
KHRBS_07565	COG3409	Peptidoglycan-binding domain 1 protein
KHRBS_07570	COG2828	Protein conserved in bacteria
KHRBS_07575	COG0583	DNA-binding transcription factor activity
KHRBS_07580	COG2851	Citrate transporter
KHRBS_07585	COG0667	Aldo Keto reductase
KHRBS_07590	COG1595	DNA-templated transcription, initiation
KHRBS_07595	COG3443	Belongs to the bacterial solute-binding protein 9 family
KHRBS_07610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KHRBS_07620	COG2070	2-Nitropropane dioxygenase
KHRBS_07630	COG2318	DinB family
KHRBS_07640	COG1335	isochorismatase
KHRBS_07655	COG2124	cytochrome p450
KHRBS_07660	COG2732	(Barnase) inhibitor
KHRBS_07665	COG1522	sequence-specific DNA binding
KHRBS_07690	COG0583	DNA-binding transcription factor activity
KHRBS_07700	COG1230	cation diffusion facilitator family transporter
KHRBS_07705	COG2072	flavoprotein involved in K transport
KHRBS_07725	COG1253	flavin adenine dinucleotide binding
KHRBS_07730	COG0456	acetyltransferase
KHRBS_07735	COG2814	Major facilitator Superfamily
KHRBS_07755	COG0662	Cupin 2, conserved barrel domain protein
KHRBS_07760	COG1937	Protein conserved in bacteria
KHRBS_07770	COG0425	Belongs to the sulfur carrier protein TusA family
KHRBS_07770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHRBS_07780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHRBS_07780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_07790	COG0730	response to heat
KHRBS_07795	COG4124	Belongs to the glycosyl hydrolase 26 family
KHRBS_07820	COG3209	COG3209 Rhs family protein
KHRBS_07835	COG0398	Pfam SNARE associated Golgi protein
KHRBS_07840	COG3409	Peptidoglycan-binding domain 1 protein
KHRBS_07840	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHRBS_07845	COG2755	lipolytic protein G-D-S-L family
KHRBS_07860	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KHRBS_07870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHRBS_07875	COG1534	Rna-binding protein
KHRBS_07880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHRBS_07885	COG1713	HD superfamily hydrolase involved in NAD metabolism
KHRBS_07890	COG0799	negative regulation of ribosome biogenesis
KHRBS_07895	COG2226	methyltransferase
KHRBS_07900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHRBS_07910	COG2131	deaminase
KHRBS_07915	COG2333	competence protein COMEC
KHRBS_07915	COG0658	competence protein
KHRBS_07925	COG1466	dna polymerase III delta subunit
KHRBS_07930	COG0268	Binds directly to 16S ribosomal RNA
KHRBS_07940	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHRBS_07955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHRBS_07960	COG1420	regulation of RNA biosynthetic process
KHRBS_07965	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHRBS_07970	COG0443	Heat shock 70 kDa protein
KHRBS_07975	COG0484	heat shock protein binding
KHRBS_07980	COG2264	protein methyltransferase activity
KHRBS_07985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHRBS_07990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHRBS_07995	COG1283	sodium-dependent phosphate transmembrane transporter activity
KHRBS_08000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KHRBS_08005	COG1610	YqeY-like protein
KHRBS_08035	COG1702	phosphate starvation-inducible protein PhoH
KHRBS_08045	COG1480	7TM receptor with intracellular HD hydrolase
KHRBS_08050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHRBS_08055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KHRBS_08060	COG0295	cytidine deaminase activity
KHRBS_08065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHRBS_08075	COG1381	Involved in DNA repair and RecF pathway recombination
KHRBS_08080	COG0752	glycyl-tRNA synthetase alpha subunit
KHRBS_08085	COG0751	glycine-tRNA ligase activity
KHRBS_08095	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KHRBS_08100	COG1671	Belongs to the UPF0178 family
KHRBS_08105	COG0358	DNA primase activity
KHRBS_08110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHRBS_08115	COG2010	Cytochrome c
KHRBS_08120	COG2384	SAM-dependent methyltransferase
KHRBS_08125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHRBS_08130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHRBS_08140	COG0513	Belongs to the DEAD box helicase family
KHRBS_08145	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHRBS_08155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHRBS_08160	COG0735	belongs to the Fur family
KHRBS_08165	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KHRBS_08170	COG4709	membrane
KHRBS_08175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHRBS_08180	COG1388	LysM domain
KHRBS_08190	COG5521	maltodextrose utilization protein MalA
KHRBS_08195	COG2839	Protein conserved in bacteria
KHRBS_08200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHRBS_08205	COG0477	Major facilitator Superfamily
KHRBS_08215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHRBS_08220	COG0573	inorganic phosphate transmembrane transporter activity
KHRBS_08225	COG0581	inorganic phosphate transmembrane transporter activity
KHRBS_08230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHRBS_08235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHRBS_08240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHRBS_08255	COG0438	transferase activity, transferring glycosyl groups
KHRBS_08260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHRBS_08265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHRBS_08280	COG4483	Protein conserved in bacteria
KHRBS_08285	COG1940	carbohydrate kinase activity
KHRBS_08305	COG0011	TIGRFAM Protein of
KHRBS_08315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_08325	COG1393	Belongs to the ArsC family
KHRBS_08335	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_08340	COG1253	flavin adenine dinucleotide binding
KHRBS_08345	COG0598	Magnesium transport protein CorA
KHRBS_08350	COG0517	IMP dehydrogenase activity
KHRBS_08360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHRBS_08365	COG1459	type II secretion system
KHRBS_08370	COG4537	Required for transformation and DNA binding
KHRBS_08385	COG4940	Competence protein ComGF
KHRBS_08410	COG0681	Belongs to the peptidase S26 family
KHRBS_08420	COG1396	sequence-specific DNA binding
KHRBS_08440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHRBS_08445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHRBS_08455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHRBS_08460	COG0095	Lipoate-protein ligase
KHRBS_08465	COG1321	iron dependent repressor
KHRBS_08480	COG3872	metal-dependent enzyme
KHRBS_08490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KHRBS_08495	COG0006	proline dipeptidase activity
KHRBS_08500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHRBS_08510	COG3854	ATPases associated with a variety of cellular activities
KHRBS_08550	COG0511	ligase activity, forming carbon-carbon bonds
KHRBS_08555	COG0439	Biotin carboxylase
KHRBS_08560	COG1302	Protein conserved in bacteria
KHRBS_08565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHRBS_08570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHRBS_08575	COG1570	exodeoxyribonuclease VII activity
KHRBS_08580	COG1722	exodeoxyribonuclease VII activity
KHRBS_08585	COG0142	geranyltranstransferase activity
KHRBS_08590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHRBS_08595	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KHRBS_08600	COG1438	arginine binding
KHRBS_08605	COG0497	DNA recombination
KHRBS_08620	COG0745	RESPONSE REGULATOR receiver
KHRBS_08630	COG1902	pentaerythritol trinitrate reductase activity
KHRBS_08645	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHRBS_08655	COG0183	Belongs to the thiolase family
KHRBS_08660	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHRBS_08665	COG1960	acyl-CoA dehydrogenase activity
KHRBS_08670	COG0372	Belongs to the citrate synthase family
KHRBS_08675	COG2079	MmgE PrpD family protein
KHRBS_08680	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KHRBS_08690	COG3290	protein histidine kinase activity
KHRBS_08690	COG3829	transcription factor binding
KHRBS_08695	COG0280	phosphate acetyltransferase
KHRBS_08700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHRBS_08705	COG3426	butyrate kinase activity
KHRBS_08710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHRBS_08715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHRBS_08720	COG0022	dehydrogenase e1 component
KHRBS_08725	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHRBS_08730	COG4978	Transcriptional regulator
KHRBS_08730	COG0789	Transcriptional regulator
KHRBS_08735	COG2814	Major facilitator Superfamily
KHRBS_08740	COG1597	lipid kinase activity
KHRBS_08750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHRBS_08755	COG0765	amino acid transport
KHRBS_08760	COG1126	abc transporter atp-binding protein
KHRBS_08765	COG4129	membrane
KHRBS_08770	COG1376	ErfK ybiS ycfS ynhG family protein
KHRBS_08780	COG0346	lactoylglutathione lyase activity
KHRBS_08785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHRBS_08790	COG2195	Cleaves the N-terminal amino acid of tripeptides
KHRBS_08795	COG3361	conserved protein (COG2071)
KHRBS_08800	COG0706	membrane insertase activity
KHRBS_08810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHRBS_08820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHRBS_08825	COG1234	tRNA 3'-trailer cleavage
KHRBS_08835	COG0596	Alpha beta hydrolase
KHRBS_08840	COG1902	pentaerythritol trinitrate reductase activity
KHRBS_08845	COG4187	Peptidase family M20/M25/M40
KHRBS_08850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHRBS_08855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_08860	COG0300	oxidoreductase activity
KHRBS_08865	COG3048	D-serine ammonia-lyase activity
KHRBS_08870	COG1072	(Pantothenic acid kinase))
KHRBS_08875	COG0346	lactoylglutathione lyase activity
KHRBS_08905	COG0456	acetyltransferase
KHRBS_08910	COG2329	Antibiotic biosynthesis monooxygenase
KHRBS_08920	COG4918	Iron-sulphur cluster biosynthesis
KHRBS_08930	COG1073	alpha beta
KHRBS_08940	COG0667	Aldo Keto reductase
KHRBS_08950	COG0494	nUDIX hydrolase
KHRBS_08955	COG1379	DNA repair
KHRBS_08960	COG1396	sequence-specific DNA binding
KHRBS_08970	COG1027	Aspartate ammonia-lyase
KHRBS_08975	COG1757	Na H antiporter
KHRBS_08980	COG0281	malic enzyme
KHRBS_08990	COG1300	Membrane
KHRBS_08995	COG0735	belongs to the Fur family
KHRBS_09005	COG4974	Belongs to the 'phage' integrase family
KHRBS_09010	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KHRBS_09015	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHRBS_09025	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_09030	COG2172	sigma factor antagonist activity
KHRBS_09035	COG1191	sigma factor activity
KHRBS_09055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHRBS_09070	COG0697	spore germination
KHRBS_09075	COG0019	diaminopimelate decarboxylase activity
KHRBS_09080	COG4086	secreted protein
KHRBS_09085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHRBS_09105	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KHRBS_09110	COG0681	Belongs to the peptidase S26 family
KHRBS_09120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHRBS_09120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHRBS_09125	COG0307	riboflavin synthase, alpha
KHRBS_09130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KHRBS_09130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KHRBS_09135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KHRBS_09140	COG0456	acetyltransferase
KHRBS_09145	COG1547	Domain of unknown function (DUF309)
KHRBS_09150	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHRBS_09155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHRBS_09165	COG1686	Belongs to the peptidase S11 family
KHRBS_09170	COG2715	membrane protein required for spore maturation
KHRBS_09175	COG0700	Nucleoside recognition
KHRBS_09180	COG1187	pseudouridine synthase activity
KHRBS_09190	COG1333	cytochrome c biogenesis protein
KHRBS_09195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHRBS_09200	COG0745	RESPONSE REGULATOR receiver
KHRBS_09205	COG5002	protein histidine kinase activity
KHRBS_09210	COG1595	DNA-templated transcription, initiation
KHRBS_09220	COG0710	3-dehydroquinate dehydratase activity
KHRBS_09225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHRBS_09230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHRBS_09235	COG1141	Ferredoxin
KHRBS_09240	COG4955	Helix-turn-helix domain
KHRBS_09245	COG0514	ATP-dependent DNA helicase (RecQ)
KHRBS_09250	COG1266	CAAX protease self-immunity
KHRBS_09255	COG1388	LysM domain
KHRBS_09265	COG1408	metallophosphoesterase
KHRBS_09270	COG4862	establishment of competence for transformation
KHRBS_09275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KHRBS_09280	COG0492	ferredoxin-NADP+ reductase activity
KHRBS_09285	COG2339	peptidase activity
KHRBS_09290	COG3773	Cell wall hydrolase
KHRBS_09290	COG3409	Peptidoglycan-binding domain 1 protein
KHRBS_09295	COG2959	enzyme of heme biosynthesis
KHRBS_09300	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KHRBS_09310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KHRBS_09315	COG0539	negative regulation of cytoplasmic translation
KHRBS_09345	COG1160	GTP binding
KHRBS_09350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHRBS_09365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KHRBS_09370	COG0776	regulation of translation
KHRBS_09375	COG0302	gtp cyclohydrolase
KHRBS_09390	COG2226	methyltransferase
KHRBS_09395	COG0142	geranyltranstransferase activity
KHRBS_09400	COG0105	UTP biosynthetic process
KHRBS_09410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KHRBS_09415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHRBS_09420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHRBS_09425	COG4401	Chorismate mutase type I
KHRBS_09430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHRBS_09435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHRBS_09445	COG0135	phosphoribosylanthranilate isomerase activity
KHRBS_09450	COG0133	tryptophan synthase activity
KHRBS_09455	COG0159	tryptophan synthase activity
KHRBS_09460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHRBS_09465	COG0287	Prephenate dehydrogenase
KHRBS_09470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KHRBS_09475	COG0457	Tetratricopeptide repeat
KHRBS_09480	COG5582	Belongs to the UPF0302 family
KHRBS_09490	COG0723	plastoquinol--plastocyanin reductase activity
KHRBS_09495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHRBS_09520	COG1694	Mazg nucleotide pyrophosphohydrolase
KHRBS_09525	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KHRBS_09530	COG1803	Methylglyoxal synthase
KHRBS_09535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHRBS_09540	COG0438	transferase activity, transferring glycosyl groups
KHRBS_09545	COG0617	tRNA 3'-terminal CCA addition
KHRBS_09555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KHRBS_09560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KHRBS_09565	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KHRBS_09580	COG5353	protein conserved in bacteria
KHRBS_09585	COG0436	Aminotransferase
KHRBS_09590	COG0017	Asparaginyl-tRNA synthetase
KHRBS_09595	COG3935	DnaD domain protein
KHRBS_09600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHRBS_09610	COG4499	WXG100 protein secretion system (Wss), protein YukC
KHRBS_09610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHRBS_09650	COG0071	Belongs to the small heat shock protein (HSP20) family
KHRBS_09655	COG2190	(PTS) system
KHRBS_09660	COG1205	dead DEAH box helicase
KHRBS_09660	COG1111	helicase
KHRBS_09665	COG3359	exonuclease
KHRBS_09675	COG4474	Belongs to the UPF0398 family
KHRBS_09705	COG1199	ATP-dependent helicase activity
KHRBS_09710	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_09715	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KHRBS_09720	COG1609	Transcriptional regulator
KHRBS_09725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHRBS_09730	COG0800	Aldolase
KHRBS_09740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KHRBS_09745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHRBS_09755	COG3424	synthase
KHRBS_09760	COG1755	Isoprenylcysteine carboxyl methyltransferase
KHRBS_09785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHRBS_09795	COG0328	RNA-DNA hybrid ribonuclease activity
KHRBS_09800	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHRBS_09805	COG0328	RNA-DNA hybrid ribonuclease activity
KHRBS_09825	COG1278	Cold shock
KHRBS_09830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHRBS_09835	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KHRBS_09840	COG0386	Belongs to the glutathione peroxidase family
KHRBS_09845	COG1418	mRNA catabolic process
KHRBS_09850	COG1413	lyase activity
KHRBS_09855	COG0129	dihydroxy-acid dehydratase activity
KHRBS_09865	COG2521	methyltransferase
KHRBS_09865	COG2136	Putative SAM-dependent methyltransferase
KHRBS_09880	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHRBS_09885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHRBS_09890	COG0204	Acyl-transferase
KHRBS_09895	COG1272	protein, Hemolysin III
KHRBS_09905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KHRBS_09920	COG1999	signal sequence binding
KHRBS_09925	COG2755	lipolytic protein G-D-S-L family
KHRBS_09930	COG4698	Protein conserved in bacteria
KHRBS_09940	COG0534	Mate efflux family protein
KHRBS_09945	COG1846	Transcriptional regulator
KHRBS_09950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHRBS_09955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHRBS_09960	COG1086	Polysaccharide biosynthesis protein
KHRBS_09965	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
KHRBS_09970	COG4641	Protein conserved in bacteria
KHRBS_09985	COG0463	Glycosyl transferase, family 2
KHRBS_09990	COG0456	acetyltransferase
KHRBS_10005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHRBS_10010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHRBS_10015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KHRBS_10020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHRBS_10025	COG0456	acetyltransferase
KHRBS_10035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHRBS_10055	COG4282	regulation of fungal-type cell wall biogenesis
KHRBS_10065	COG5444	nuclease activity
KHRBS_10115	COG0457	Tetratricopeptide repeat
KHRBS_10155	COG2433	Pfam Transposase IS66
KHRBS_10190	COG0582	viral genome integration into host DNA
KHRBS_10290	COG4373	Mu-like prophage FluMu protein gp28
KHRBS_10325	COG0776	regulation of translation
KHRBS_10505	COG0582	viral genome integration into host DNA
KHRBS_10520	COG3655	Transcriptional regulator
KHRBS_10630	COG1793	dna ligase
KHRBS_10635	COG2135	peptidase activity
KHRBS_10695	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KHRBS_10705	COG3584	3D domain protein
KHRBS_10730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHRBS_10735	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KHRBS_10840	COG1780	Probably involved in ribonucleotide reductase function
KHRBS_10855	COG1372	Participates in initiation and elongation during chromosome replication
KHRBS_10855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHRBS_10885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_10900	COG0756	dUTP diphosphatase activity
KHRBS_10925	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHRBS_10930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHRBS_10960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KHRBS_11010	COG3331	DNA recombination
KHRBS_11015	COG2337	Toxic component of a toxin-antitoxin (TA) module
KHRBS_11030	COG1509	lysine 2,3-aminomutase activity
KHRBS_11040	COG4479	Belongs to the UPF0346 family
KHRBS_11065	COG0671	phosphoesterase, PA-phosphatase related
KHRBS_11080	COG0813	purine-nucleoside phosphorylase activity
KHRBS_11085	COG1876	peptidase activity
KHRBS_11115	COG0346	lactoylglutathione lyase activity
KHRBS_11120	COG0400	carboxylic ester hydrolase activity
KHRBS_11125	COG0778	Nitroreductase
KHRBS_11130	COG1733	regulation of RNA biosynthetic process
KHRBS_11135	COG1942	4-Oxalocrotonate Tautomerase
KHRBS_11140	COG2610	gluconate transmembrane transporter activity
KHRBS_11155	COG2962	Rard protein
KHRBS_11165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHRBS_11170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHRBS_11175	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_11185	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHRBS_11190	COG1819	glycosyl
KHRBS_11195	COG0791	NLP P60 protein
KHRBS_11195	COG1388	LysM domain
KHRBS_11200	COG2032	superoxide dismutase activity
KHRBS_11205	COG0714	Associated with various cellular activities
KHRBS_11210	COG4548	von Willebrand factor, type A
KHRBS_11215	COG0567	Dehydrogenase, E1 component
KHRBS_11220	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHRBS_11225	COG0385	Bile acid
KHRBS_11230	COG0733	neurotransmitter:sodium symporter activity
KHRBS_11235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHRBS_11245	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_11270	COG0071	Belongs to the small heat shock protein (HSP20) family
KHRBS_11290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHRBS_11305	COG0514	ATP-dependent DNA helicase (RecQ)
KHRBS_11310	COG1388	LysM domain
KHRBS_11310	COG3584	3D domain protein
KHRBS_11315	COG2197	response regulator
KHRBS_11325	COG3239	Fatty acid desaturase
KHRBS_11330	COG1619	proteins homologs of microcin C7 resistance protein MccF
KHRBS_11345	COG2322	membrane
KHRBS_11350	COG0741	lytic transglycosylase activity
KHRBS_11355	COG0640	Transcriptional regulator
KHRBS_11365	COG2378	regulation of single-species biofilm formation
KHRBS_11370	COG3708	Transcriptional regulator
KHRBS_11375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_11380	COG1309	transcriptional regulator
KHRBS_11385	COG0456	acetyltransferase
KHRBS_11390	COG2207	Transcriptional regulator
KHRBS_11390	COG0662	Cupin 2, conserved barrel domain protein
KHRBS_11395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHRBS_11400	COG1231	oxidoreductase activity
KHRBS_11405	COG4282	regulation of fungal-type cell wall biogenesis
KHRBS_11430	COG1175	transmembrane transport
KHRBS_11435	COG0395	ABC-type sugar transport system, permease component
KHRBS_11485	COG1396	sequence-specific DNA binding
KHRBS_11490	COG2314	TM2 domain
KHRBS_11500	COG0726	polysaccharide deacetylase
KHRBS_11505	COG3848	Pyruvate phosphate dikinase
KHRBS_11505	COG0574	Belongs to the PEP-utilizing enzyme family
KHRBS_11530	COG2367	Beta-lactamase
KHRBS_11535	COG0693	protein deglycase activity
KHRBS_11545	COG0697	spore germination
KHRBS_11550	COG0583	DNA-binding transcription factor activity
KHRBS_11555	COG3739	integral membrane protein
KHRBS_11560	COG3655	Transcriptional regulator
KHRBS_11570	COG2720	vancomycin resistance protein
KHRBS_11590	COG2140	Oxalate decarboxylase
KHRBS_11600	COG2135	peptidase activity
KHRBS_11605	COG3866	Pectate lyase
KHRBS_11610	COG3619	membrane
KHRBS_11615	COG4305	rare lipoprotein A
KHRBS_11620	COG2368	4-hydroxyphenylacetate
KHRBS_11625	COG0840	transmembrane signaling receptor activity
KHRBS_11625	COG5278	phosphoserine phosphatase activity
KHRBS_11655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHRBS_11660	COG1070	Carbohydrate kinase
KHRBS_11665	COG2814	Major facilitator Superfamily
KHRBS_11675	COG1131	(ABC) transporter
KHRBS_11690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_11700	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHRBS_11705	COG0300	oxidoreductase activity
KHRBS_11715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHRBS_11720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHRBS_11725	COG0583	DNA-binding transcription factor activity
KHRBS_11735	COG0493	'glutamate synthase
KHRBS_11740	COG0604	alcohol dehydrogenase
KHRBS_11745	COG0583	DNA-binding transcription factor activity
KHRBS_11750	COG0405	Gamma-glutamyltransferase
KHRBS_11755	COG0166	Belongs to the GPI family
KHRBS_11760	COG0582	viral genome integration into host DNA
KHRBS_11775	COG0534	Mate efflux family protein
KHRBS_11780	COG2017	converts alpha-aldose to the beta-anomer
KHRBS_11785	COG2027	D-alanyl-D-alanine carboxypeptidase
KHRBS_11790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_11795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_11800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_11810	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KHRBS_11810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_11820	COG1649	PFAM Uncharacterised BCR, COG1649
KHRBS_11835	COG1960	acyl-CoA dehydrogenase activity
KHRBS_11840	COG0318	PFAM AMP-dependent synthetase and ligase
KHRBS_11845	COG0439	Biotin carboxylase
KHRBS_11850	COG0511	ligase activity, forming carbon-carbon bonds
KHRBS_11855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHRBS_11860	COG1024	Enoyl-CoA hydratase
KHRBS_11870	COG2404	hydrolase activity, acting on ester bonds
KHRBS_11875	COG0586	Pfam SNARE associated Golgi protein
KHRBS_11880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHRBS_11885	COG2246	polysaccharide biosynthetic process
KHRBS_11890	COG3507	Belongs to the glycosyl hydrolase 43 family
KHRBS_11895	COG5520	Belongs to the glycosyl hydrolase 30 family
KHRBS_11910	COG1115	amino acid carrier protein
KHRBS_11930	COG0187	DNA topoisomerase II activity
KHRBS_11935	COG1832	CoA-binding protein
KHRBS_11940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KHRBS_11945	COG4841	protein insertion into membrane
KHRBS_11955	COG0824	Thioesterase
KHRBS_11975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_11995	COG0071	Belongs to the small heat shock protein (HSP20) family
KHRBS_12005	COG4846	Membrane protein involved in cytochrome C biogenesis
KHRBS_12010	COG2201	protein-glutamate methylesterase activity
KHRBS_12025	COG3763	UPF0154 protein
KHRBS_12035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHRBS_12040	COG4224	UPF0291 protein
KHRBS_12050	COG1388	LysM domain
KHRBS_12055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHRBS_12065	COG0346	lactoylglutathione lyase activity
KHRBS_12075	COG4195	phage-related replication protein
KHRBS_12105	COG0531	amino acid
KHRBS_12125	COG3832	glyoxalase III activity
KHRBS_12140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHRBS_12180	COG0756	dUTP diphosphatase activity
KHRBS_12195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHRBS_12200	COG2814	Major facilitator Superfamily
KHRBS_12205	COG1525	nuclease
KHRBS_12210	COG1070	Carbohydrate kinase
KHRBS_12215	COG2115	Belongs to the xylose isomerase family
KHRBS_12220	COG1940	carbohydrate kinase activity
KHRBS_12225	COG3507	Belongs to the glycosyl hydrolase 43 family
KHRBS_12230	COG2211	Major facilitator Superfamily
KHRBS_12235	COG0135	phosphoribosylanthranilate isomerase activity
KHRBS_12260	COG3655	Transcriptional regulator
KHRBS_12290	COG4282	regulation of fungal-type cell wall biogenesis
KHRBS_12310	COG0174	glutamine synthetase
KHRBS_12315	COG0789	Transcriptional regulator
KHRBS_12320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KHRBS_12325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHRBS_12335	COG0464	growth
KHRBS_12340	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHRBS_12345	COG4112	unkown
KHRBS_12350	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHRBS_12360	COG1780	Probably involved in ribonucleotide reductase function
KHRBS_12375	COG1923	regulation of RNA biosynthetic process
KHRBS_12380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHRBS_12395	COG2076	Multidrug Resistance protein
KHRBS_12400	COG2076	Multidrug Resistance protein
KHRBS_12405	COG1764	response to oxidative stress
KHRBS_12410	COG4195	phage-related replication protein
KHRBS_12420	COG1404	Belongs to the peptidase S8 family
KHRBS_12425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_12445	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_12445	COG4221	oxidoreductase activity
KHRBS_12445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_12445	COG3321	synthase
KHRBS_12450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHRBS_12450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_12450	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_12450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHRBS_12450	COG3321	synthase
KHRBS_12455	COG4221	oxidoreductase activity
KHRBS_12455	COG3321	synthase
KHRBS_12455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHRBS_12455	COG0300	oxidoreductase activity
KHRBS_12465	COG1024	Enoyl-CoA hydratase
KHRBS_12470	COG1024	Enoyl-CoA hydratase
KHRBS_12475	COG3425	synthase
KHRBS_12480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHRBS_12485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHRBS_12490	COG2070	2-Nitropropane dioxygenase
KHRBS_12490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHRBS_12495	COG3321	synthase
KHRBS_12505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHRBS_12515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_12520	COG3226	Transcriptional regulator
KHRBS_12540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHRBS_12545	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHRBS_12555	COG4550	Control of competence regulator ComK, YlbF/YmcA
KHRBS_12560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHRBS_12565	COG0156	8-amino-7-oxononanoate synthase activity
KHRBS_12570	COG1063	alcohol dehydrogenase
KHRBS_12575	COG2359	stage V sporulation protein S
KHRBS_12580	COG1692	metallophosphoesterase
KHRBS_12585	COG1418	mRNA catabolic process
KHRBS_12590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHRBS_12595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHRBS_12605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHRBS_12625	COG0300	oxidoreductase activity
KHRBS_12630	COG0612	Peptidase, M16
KHRBS_12635	COG0612	Peptidase, M16
KHRBS_12645	COG2188	Transcriptional regulator
KHRBS_12660	COG0740	serine-type endopeptidase activity
KHRBS_12665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHRBS_12670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHRBS_12680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHRBS_12690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHRBS_12700	COG1873	PFAM PRC-barrel domain
KHRBS_12710	COG0726	polysaccharide deacetylase
KHRBS_12715	COG1185	polyribonucleotide nucleotidyltransferase activity
KHRBS_12720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHRBS_12725	COG0196	riboflavin kinase activity
KHRBS_12730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHRBS_12735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHRBS_12740	COG1550	Protein conserved in bacteria
KHRBS_12745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHRBS_12750	COG1358	cellular component organization or biogenesis
KHRBS_12755	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KHRBS_12760	COG0195	Participates in both transcription termination and antitermination
KHRBS_12765	COG0779	Required for maturation of 30S ribosomal subunits
KHRBS_12770	COG2176	DNA-directed DNA polymerase activity
KHRBS_12775	COG0442	prolyl-tRNA aminoacylation
KHRBS_12780	COG0750	zinc metalloprotease
KHRBS_12785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KHRBS_12790	COG4589	Belongs to the CDS family
KHRBS_12795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHRBS_12800	COG0233	cytoplasmic translational termination
KHRBS_12805	COG0528	UMP kinase activity
KHRBS_12810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHRBS_12825	COG1191	sigma factor activity
KHRBS_12830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KHRBS_12835	COG1776	CheC inhibitor of MCP methylation
KHRBS_12840	COG0835	chemotaxis
KHRBS_12845	COG0643	Histidine kinase
KHRBS_12845	COG2198	Histidine kinase
KHRBS_12850	COG2201	protein-glutamate methylesterase activity
KHRBS_12855	COG0455	bacterial-type flagellum organization
KHRBS_12860	COG1419	protein localization to endoplasmic reticulum
KHRBS_12865	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHRBS_12870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHRBS_12875	COG1684	flagellar biosynthetic protein fliR
KHRBS_12880	COG1987	bacterial-type flagellum assembly
KHRBS_12885	COG1338	Plays a role in the flagellum-specific transport system
KHRBS_12895	COG2201	protein-glutamate methylesterase activity
KHRBS_12900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHRBS_12900	COG1776	CheC inhibitor of MCP methylation
KHRBS_12910	COG1580	Controls the rotational direction of flagella during chemotaxis
KHRBS_12915	COG1582	Flagellar protein (FlbD)
KHRBS_12920	COG4786	Flagellar basal body rod
KHRBS_12925	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KHRBS_12930	COG3144	bacterial-type flagellum assembly
KHRBS_12940	COG2882	bacterial-type flagellum organization
KHRBS_12945	COG1157	protein secretion by the type III secretion system
KHRBS_12950	COG1317	bacterial-type flagellum organization
KHRBS_12960	COG1766	The M ring may be actively involved in energy transduction
KHRBS_12965	COG1677	Flagellar hook-basal body complex protein FliE
KHRBS_12970	COG1558	bacterial-type flagellum-dependent cell motility
KHRBS_12975	COG1815	bacterial-type flagellum-dependent cell motility
KHRBS_12980	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KHRBS_12985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHRBS_12990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHRBS_12995	COG4974	Belongs to the 'phage' integrase family
KHRBS_13005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHRBS_13010	COG0758	DNA mediated transformation
KHRBS_13015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHRBS_13020	COG0045	succinate-CoA ligase (ADP-forming) activity
KHRBS_13025	COG2257	FlhB HrpN YscU SpaS Family
KHRBS_13035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHRBS_13040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHRBS_13045	COG0335	large ribosomal subunit rRNA binding
KHRBS_13050	COG0336	Belongs to the RNA methyltransferase TrmD family
KHRBS_13055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHRBS_13065	COG1837	Belongs to the UPF0109 family
KHRBS_13070	COG0228	four-way junction DNA binding
KHRBS_13075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHRBS_13080	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHRBS_13090	COG0552	protein localization to endoplasmic reticulum
KHRBS_13100	COG0571	ribonuclease III activity
KHRBS_13105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHRBS_13110	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_13120	COG0416	fatty acid biosynthetic process
KHRBS_13125	COG1349	DNA-binding transcription factor activity
KHRBS_13125	COG2050	protein possibly involved in aromatic compounds catabolism
KHRBS_13130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHRBS_13135	COG1760	l-serine dehydratase
KHRBS_13140	COG1760	l-serine dehydratase
KHRBS_13145	COG1461	Dihydroxyacetone kinase
KHRBS_13150	COG1302	Protein conserved in bacteria
KHRBS_13155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KHRBS_13165	COG1564	THIamine pyrophosphokinase
KHRBS_13170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KHRBS_13175	COG1162	GTPase activity
KHRBS_13180	COG2815	serine threonine protein kinase
KHRBS_13180	COG0515	serine threonine protein kinase
KHRBS_13185	COG0631	protein serine/threonine phosphatase activity
KHRBS_13190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KHRBS_13195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHRBS_13195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHRBS_13200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHRBS_13205	COG0242	peptide deformylase activity
KHRBS_13220	COG1758	RNA polymerase activity
KHRBS_13225	COG0194	GDP metabolic process
KHRBS_13230	COG2052	Domain of unknown function (DUF370)
KHRBS_13235	COG1561	YicC-like family, N-terminal region
KHRBS_13240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHRBS_13255	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KHRBS_13260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHRBS_13265	COG0529	Catalyzes the synthesis of activated sulfate
KHRBS_13270	COG2046	Belongs to the sulfate adenylyltransferase family
KHRBS_13275	COG0306	phosphate transporter
KHRBS_13280	COG0175	sulfate reduction
KHRBS_13285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHRBS_13295	COG0167	dihydroorotate dehydrogenase activity
KHRBS_13300	COG0543	2 iron, 2 sulfur cluster binding
KHRBS_13305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHRBS_13310	COG0505	Belongs to the CarA family
KHRBS_13320	COG0540	Belongs to the ATCase OTCase family
KHRBS_13325	COG2233	PERMEase
KHRBS_13330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHRBS_13335	COG0564	pseudouridine synthase activity
KHRBS_13340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHRBS_13345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHRBS_13350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHRBS_13355	COG3599	regulation of cell shape
KHRBS_13365	COG0762	integral membrane protein
KHRBS_13370	COG1799	cell septum assembly
KHRBS_13375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHRBS_13385	COG1873	PFAM PRC-barrel domain
KHRBS_13395	COG1119	ATPase activity
KHRBS_13400	COG1191	sigma factor activity
KHRBS_13420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHRBS_13425	COG0849	cell division
KHRBS_13430	COG3856	small basic protein
KHRBS_13435	COG3879	Bacterial protein of unknown function (DUF881)
KHRBS_13440	COG3879	Bacterial protein of unknown function (DUF881)
KHRBS_13445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KHRBS_13450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KHRBS_13455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHRBS_13460	COG0772	Belongs to the SEDS family
KHRBS_13465	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHRBS_13470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHRBS_13480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHRBS_13490	COG0768	penicillin binding
KHRBS_13505	COG4839	cell division protein FtsL
KHRBS_13510	COG0275	rRNA processing
KHRBS_13515	COG2001	Belongs to the MraZ family
KHRBS_13520	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KHRBS_13525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHRBS_13530	COG0454	-acetyltransferase
KHRBS_13540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KHRBS_13545	COG1399	metal-binding, possibly nucleic acid-binding protein
KHRBS_13555	COG1323	Belongs to the UPF0348 family
KHRBS_13560	COG3480	Lon protease (S16) C-terminal proteolytic domain
KHRBS_13565	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHRBS_13570	COG3314	Sporulation integral membrane protein YlbJ
KHRBS_13575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHRBS_13580	COG0742	ribosomal rna small subunit methyltransferase
KHRBS_13585	COG4471	UPF0298 protein
KHRBS_13590	COG3679	Belongs to the UPF0342 family
KHRBS_13605	COG2340	Cysteine-rich secretory protein family
KHRBS_13610	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KHRBS_13620	COG3336	cytochrome c oxidase
KHRBS_13625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KHRBS_13630	COG1845	cytochrome c oxidase, subunit III
KHRBS_13635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHRBS_13640	COG2010	Cytochrome c
KHRBS_13640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHRBS_13645	COG0109	protoheme IX farnesyltransferase activity
KHRBS_13650	COG1612	heme a metabolic process
KHRBS_13655	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KHRBS_13665	COG4838	Belongs to the UPF0358 family
KHRBS_13670	COG2066	Belongs to the glutaminase family
KHRBS_13675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHRBS_13680	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KHRBS_13690	COG4896	Protein conserved in bacteria
KHRBS_13720	COG1595	DNA-templated transcription, initiation
KHRBS_13740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KHRBS_13750	COG0483	inositol monophosphate 1-phosphatase activity
KHRBS_13760	COG4493	Belongs to the UPF0637 family
KHRBS_13765	COG4476	Belongs to the UPF0223 family
KHRBS_13770	COG1982	Orn Lys Arg decarboxylase major
KHRBS_13775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_13780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHRBS_13785	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHRBS_13790	COG0022	dehydrogenase e1 component
KHRBS_13795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHRBS_13810	COG0242	peptide deformylase activity
KHRBS_13815	COG0561	phosphatase activity
KHRBS_13825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHRBS_13830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHRBS_13835	COG0569	domain protein
KHRBS_13840	COG2105	PFAM AIG2 family protein
KHRBS_13840	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KHRBS_13845	COG3852	Histidine kinase
KHRBS_13850	COG2002	toxin-antitoxin pair type II binding
KHRBS_13855	COG1077	Cell shape determining protein MreB Mrl
KHRBS_13865	COG2309	aminopeptidase activity
KHRBS_13870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHRBS_13875	COG0488	(ABC) transporter
KHRBS_13885	COG0681	Belongs to the peptidase S26 family
KHRBS_13890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_13890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHRBS_13890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHRBS_13895	COG1105	Belongs to the carbohydrate kinase PfkB family
KHRBS_13900	COG1349	DNA-binding transcription factor activity
KHRBS_13905	COG0577	efflux transmembrane transporter activity
KHRBS_13910	COG1136	(ABC) transporter
KHRBS_13915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHRBS_13925	COG1132	(ABC) transporter
KHRBS_13930	COG1132	(ABC) transporter
KHRBS_13935	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KHRBS_13940	COG0314	molybdopterin synthase activity
KHRBS_13945	COG1763	Mo-molybdopterin cofactor biosynthetic process
KHRBS_13950	COG0303	'Molybdopterin
KHRBS_13955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHRBS_13960	COG0746	molybdenum cofactor guanylyltransferase activity
KHRBS_13980	COG0450	alkyl hydroperoxide reductase
KHRBS_13985	COG0668	transmembrane transport
KHRBS_14000	COG2171	N-acyltransferase activity
KHRBS_14005	COG0716	FMN binding
KHRBS_14015	COG0716	FMN binding
KHRBS_14020	COG0583	DNA-binding transcription factor activity
KHRBS_14025	COG0517	IMP dehydrogenase activity
KHRBS_14035	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KHRBS_14040	COG4703	Protein of unknown function (DUF1797)
KHRBS_14050	COG2200	EAL domain
KHRBS_14070	COG1408	metallophosphoesterase
KHRBS_14075	COG1376	ErfK ybiS ycfS ynhG family protein
KHRBS_14080	COG2814	Major facilitator Superfamily
KHRBS_14090	COG0784	Response regulator, receiver
KHRBS_14090	COG0835	chemotaxis
KHRBS_14100	COG0436	Aminotransferase
KHRBS_14110	COG0768	penicillin binding
KHRBS_14120	COG2084	Dehydrogenase
KHRBS_14125	COG0840	transmembrane signaling receptor activity
KHRBS_14130	COG1533	DNA photolyase activity
KHRBS_14140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHRBS_14145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_14150	COG1263	PTS System
KHRBS_14150	COG2190	(PTS) system
KHRBS_14150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_14155	COG3711	transcriptional antiterminator
KHRBS_14160	COG1609	Transcriptional regulator
KHRBS_14170	COG0006	proline dipeptidase activity
KHRBS_14180	COG2217	Heavy metal translocating P-type atpase
KHRBS_14185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_14190	COG2244	polysaccharide biosynthetic process
KHRBS_14195	COG3773	Cell wall hydrolase
KHRBS_14210	COG4873	Protein conserved in bacteria
KHRBS_14220	COG3858	chitin binding
KHRBS_14225	COG1388	LysM domain
KHRBS_14230	COG1388	LysM domain
KHRBS_14230	COG4641	Protein conserved in bacteria
KHRBS_14235	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_14240	COG1733	regulation of RNA biosynthetic process
KHRBS_14245	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KHRBS_14250	COG0602	queuosine metabolic process
KHRBS_14255	COG0720	synthase
KHRBS_14260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KHRBS_14265	COG3949	Membrane
KHRBS_14270	COG0542	response to heat
KHRBS_14275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHRBS_14280	COG1360	Flagellar Motor Protein
KHRBS_14285	COG1846	Transcriptional regulator
KHRBS_14290	COG3852	Histidine kinase
KHRBS_14305	COG3339	Conserved Protein
KHRBS_14310	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KHRBS_14315	COG0235	Class ii aldolase
KHRBS_14320	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KHRBS_14325	COG1850	ribulose-bisphosphate carboxylase activity
KHRBS_14335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHRBS_14340	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KHRBS_14345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KHRBS_14355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHRBS_14365	COG3594	Acyltransferase
KHRBS_14380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHRBS_14385	COG0501	Belongs to the peptidase M48B family
KHRBS_14405	COG1191	sigma factor activity
KHRBS_14410	COG0861	Integral membrane protein TerC family
KHRBS_14415	COG0586	Pfam SNARE associated Golgi protein
KHRBS_14420	COG5001	Diguanylate cyclase
KHRBS_14420	COG3300	MHYT domain
KHRBS_14425	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KHRBS_14435	COG0463	Glycosyl transferase, family 2
KHRBS_14455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHRBS_14460	COG1846	Transcriptional regulator
KHRBS_14475	COG0789	Transcriptional regulator
KHRBS_14480	COG2239	Acts as a magnesium transporter
KHRBS_14495	COG3212	peptidase
KHRBS_14505	COG3850	Histidine kinase
KHRBS_14505	COG5002	protein histidine kinase activity
KHRBS_14510	COG0745	RESPONSE REGULATOR receiver
KHRBS_14520	COG4721	ABC-type cobalt transport system, permease component
KHRBS_14525	COG1122	ATPase activity
KHRBS_14530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHRBS_14535	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_14540	COG1404	Belongs to the peptidase S8 family
KHRBS_14545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHRBS_14550	COG0590	tRNA wobble adenosine to inosine editing
KHRBS_14560	COG1764	response to oxidative stress
KHRBS_14565	COG1846	Transcriptional regulator
KHRBS_14570	COG1764	response to oxidative stress
KHRBS_14575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHRBS_14580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHRBS_14585	COG0788	formyltetrahydrofolate deformylase activity
KHRBS_14590	COG2076	Multidrug Resistance protein
KHRBS_14595	COG2076	Multidrug Resistance protein
KHRBS_14600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_14605	COG2318	DinB family
KHRBS_14610	COG2323	membrane
KHRBS_14625	COG1607	acyl-coa hydrolase
KHRBS_14630	COG1834	amidinotransferase
KHRBS_14635	COG2706	6-phosphogluconolactonase activity
KHRBS_14640	COG4608	Belongs to the ABC transporter superfamily
KHRBS_14645	COG0791	NLP P60 protein
KHRBS_14650	COG4948	Mandelate Racemase Muconate Lactonizing
KHRBS_14655	COG1619	proteins homologs of microcin C7 resistance protein MccF
KHRBS_14660	COG4166	transmembrane transport
KHRBS_14665	COG0444	Belongs to the ABC transporter superfamily
KHRBS_14685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHRBS_14690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHRBS_14700	COG0463	Glycosyl transferase, family 2
KHRBS_14705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHRBS_14710	COG0346	lactoylglutathione lyase activity
KHRBS_14715	COG0531	amino acid
KHRBS_14720	COG1392	Phosphate transport regulator
KHRBS_14725	COG0306	phosphate transporter
KHRBS_14740	COG3409	Peptidoglycan-binding domain 1 protein
KHRBS_14740	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHRBS_14780	COG3778	Protein conserved in bacteria
KHRBS_14785	COG3299	homolog of phage Mu protein gp47
KHRBS_14790	COG3628	GPW Gp25 family protein
KHRBS_14800	COG4193	domain, Protein
KHRBS_14805	COG1652	LysM domain
KHRBS_14810	COG3953	SLT domain
KHRBS_14810	COG5412	phage tail tape measure protein
KHRBS_14810	COG3953	SLT domain
KHRBS_14810	COG5412	phage tail tape measure protein
KHRBS_14860	COG4653	Phage capsid family
KHRBS_14865	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KHRBS_14870	COG5518	Phage portal protein
KHRBS_14875	COG1783	phage Terminase large subunit
KHRBS_14880	COG5484	DNA packaging
KHRBS_14880	COG3728	DNA packaging
KHRBS_14885	COG1595	DNA-templated transcription, initiation
KHRBS_14910	COG1484	DNA-dependent DNA replication
KHRBS_14925	COG1396	sequence-specific DNA binding
KHRBS_14930	COG2856	Zn peptidase
KHRBS_14935	COG3546	catalase activity
KHRBS_14940	COG4195	phage-related replication protein
KHRBS_14950	COG1388	LysM domain
KHRBS_14950	COG3409	Peptidoglycan-binding domain 1 protein
KHRBS_14950	COG5632	N-Acetylmuramoyl-L-alanine amidase
KHRBS_14955	COG2350	Protein conserved in bacteria
KHRBS_14970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHRBS_14975	COG2318	DinB family
KHRBS_14980	COG0730	response to heat
KHRBS_14985	COG2721	sulfolactate sulfo-lyase activity
KHRBS_14995	COG1609	Transcriptional regulator
KHRBS_15000	COG2271	Major facilitator Superfamily
KHRBS_15005	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_15010	COG1312	Catalyzes the dehydration of D-mannonate
KHRBS_15015	COG1063	alcohol dehydrogenase
KHRBS_15020	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KHRBS_15025	COG2211	Major facilitator Superfamily
KHRBS_15030	COG1904	glucuronate isomerase
KHRBS_15045	COG4297	protein containing double-stranded beta helix domain
KHRBS_15050	COG0697	spore germination
KHRBS_15055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHRBS_15060	COG0390	transport system, permease component
KHRBS_15065	COG1587	Uroporphyrinogen-III synthase
KHRBS_15080	COG2124	cytochrome p450
KHRBS_15100	COG2427	Protein of unknown function (DUF1641)
KHRBS_15105	COG3383	formate dehydrogenase (NAD+) activity
KHRBS_15115	COG2205	protein histidine kinase activity
KHRBS_15120	COG5504	Zn-dependent protease
KHRBS_15140	COG0726	polysaccharide deacetylase
KHRBS_15150	COG0109	protoheme IX farnesyltransferase activity
KHRBS_15165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHRBS_15175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_15185	COG1482	cell wall glycoprotein biosynthetic process
KHRBS_15195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_15195	COG3711	transcriptional antiterminator
KHRBS_15205	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_15210	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KHRBS_15225	COG3677	Transposase
KHRBS_15260	COG5505	Protein of unknown function (DUF819)
KHRBS_15265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_15270	COG0626	cystathionine gamma-synthase activity
KHRBS_15275	COG0626	cystathionine gamma-synthase activity
KHRBS_15305	COG2382	esterase
KHRBS_15310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KHRBS_15315	COG2153	protein acetylation
KHRBS_15325	COG0210	DNA helicase
KHRBS_15385	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KHRBS_15390	COG0351	phosphomethylpyrimidine kinase
KHRBS_15395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHRBS_15400	COG2022	thiamine diphosphate biosynthetic process
KHRBS_15405	COG2104	thiamine diphosphate biosynthetic process
KHRBS_15420	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KHRBS_15430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KHRBS_15435	COG0564	pseudouridine synthase activity
KHRBS_15440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHRBS_15455	COG4116	CYTH
KHRBS_15460	COG0741	lytic transglycosylase activity
KHRBS_15465	COG2346	COG2346, Truncated hemoglobins
KHRBS_15485	COG1164	Oligoendopeptidase f
KHRBS_15490	COG4469	Competence protein
KHRBS_15495	COG4862	establishment of competence for transformation
KHRBS_15500	COG0861	Integral membrane protein TerC family
KHRBS_15505	COG1393	Belongs to the ArsC family
KHRBS_15510	COG0456	acetyltransferase
KHRBS_15515	COG2814	Major facilitator Superfamily
KHRBS_15520	COG4608	Belongs to the ABC transporter superfamily
KHRBS_15525	COG0444	Belongs to the ABC transporter superfamily
KHRBS_15530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHRBS_15535	COG0601	transmembrane transport
KHRBS_15540	COG4166	transmembrane transport
KHRBS_15545	COG0180	Tryptophanyl-tRNA synthetase
KHRBS_15555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHRBS_15560	COG0601	transmembrane transport
KHRBS_15570	COG4608	Belongs to the ABC transporter superfamily
KHRBS_15575	COG0444	Belongs to the ABC transporter superfamily
KHRBS_15580	COG5504	Zn-dependent protease
KHRBS_15585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHRBS_15590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHRBS_15605	COG1744	ABC transporter substrate-binding protein PnrA-like
KHRBS_15630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHRBS_15645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHRBS_15660	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHRBS_15665	COG2271	Major facilitator Superfamily
KHRBS_15670	COG0277	FAD linked oxidase domain protein
KHRBS_15680	COG2151	metal-sulfur cluster biosynthetic enzyme
KHRBS_15685	COG1073	alpha beta
KHRBS_15690	COG0561	phosphatase activity
KHRBS_15710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHRBS_15715	COG1307	EDD domain protein, DegV family
KHRBS_15720	COG3227	Zinc metalloprotease (Elastase)
KHRBS_15735	COG1695	Transcriptional regulator
KHRBS_15755	COG2996	Protein conserved in bacteria
KHRBS_15760	COG1666	GTP binding
KHRBS_15765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KHRBS_15765	COG0646	methionine synthase
KHRBS_15770	COG2153	protein acetylation
KHRBS_15775	COG0454	-acetyltransferase
KHRBS_15780	COG2814	Major facilitator Superfamily
KHRBS_15785	COG4948	Mandelate Racemase Muconate Lactonizing
KHRBS_15790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHRBS_15795	COG1809	phosphosulfolactate synthase activity
KHRBS_15800	COG2045	Belongs to the ComB family
KHRBS_15805	COG0175	sulfate reduction
KHRBS_15810	COG2046	Belongs to the sulfate adenylyltransferase family
KHRBS_15815	COG0529	Catalyzes the synthesis of activated sulfate
KHRBS_15820	COG2267	carboxylic ester hydrolase activity
KHRBS_15825	COG1357	PFAM Pentapeptide repeats (8 copies)
KHRBS_15830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHRBS_15835	COG1279	arginine transmembrane transporter activity
KHRBS_15840	COG2318	DinB family
KHRBS_15845	COG0673	inositol 2-dehydrogenase activity
KHRBS_15850	COG1609	Transcriptional regulator
KHRBS_15855	COG2207	Transcriptional regulator
KHRBS_15855	COG1917	Cupin 2, conserved barrel domain protein
KHRBS_15860	COG0534	Mate efflux family protein
KHRBS_15865	COG1562	ergosterol biosynthetic process
KHRBS_15875	COG0367	asparagine synthase
KHRBS_15885	COG1404	Belongs to the peptidase S8 family
KHRBS_15895	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHRBS_15900	COG5337	Spore coat protein CotH
KHRBS_15945	COG1403	HNH endonuclease
KHRBS_15955	COG0420	3'-5' exonuclease activity
KHRBS_15960	COG1074	ATP-dependent DNA helicase activity
KHRBS_15965	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KHRBS_15970	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KHRBS_15980	COG4533	DNA binding
KHRBS_15985	COG2814	Major facilitator Superfamily
KHRBS_15985	COG0477	Major facilitator Superfamily
KHRBS_15990	COG3180	Ammonia monooxygenase
KHRBS_16005	COG0561	phosphatase activity
KHRBS_16025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHRBS_16030	COG0681	Belongs to the peptidase S26 family
KHRBS_16035	COG0398	Pfam SNARE associated Golgi protein
KHRBS_16050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHRBS_16060	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_16065	COG4903	ComK protein
KHRBS_16075	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_16080	COG0723	plastoquinol--plastocyanin reductase activity
KHRBS_16080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHRBS_16085	COG0840	transmembrane signaling receptor activity
KHRBS_16090	COG1268	BioY protein
KHRBS_16095	COG0318	PFAM AMP-dependent synthetase and ligase
KHRBS_16100	COG0183	Belongs to the thiolase family
KHRBS_16105	COG0406	alpha-ribazole phosphatase activity
KHRBS_16110	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KHRBS_16115	COG0604	alcohol dehydrogenase
KHRBS_16120	COG0456	acetyltransferase
KHRBS_16125	COG1404	Belongs to the peptidase S8 family
KHRBS_16130	COG0501	Belongs to the peptidase M48B family
KHRBS_16140	COG0318	PFAM AMP-dependent synthetase and ligase
KHRBS_16145	COG0702	epimerase
KHRBS_16150	COG0095	Lipoate-protein ligase
KHRBS_16155	COG1234	tRNA 3'-trailer cleavage
KHRBS_16175	COG4405	Protein conserved in bacteria
KHRBS_16180	COG1363	Peptidase, m42
KHRBS_16190	COG4377	Putative membrane peptidase family (DUF2324)
KHRBS_16200	COG1511	domain protein
KHRBS_16205	COG1309	transcriptional regulator
KHRBS_16220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KHRBS_16225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHRBS_16230	COG2329	Antibiotic biosynthesis monooxygenase
KHRBS_16240	COG3069	C4-dicarboxylate transmembrane transporter activity
KHRBS_16260	COG1131	(ABC) transporter
KHRBS_16265	COG0537	adenosine 5'-monophosphoramidase activity
KHRBS_16270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHRBS_16285	COG4980	gas vesicle protein
KHRBS_16310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHRBS_16320	COG3481	metal-dependent phosphohydrolase, HD sub domain
KHRBS_16325	COG4717	serine-type aminopeptidase activity
KHRBS_16330	COG0420	3'-5' exonuclease activity
KHRBS_16335	COG1668	transmembrane transport
KHRBS_16340	COG4152	abc transporter atp-binding protein
KHRBS_16350	COG1024	Enoyl-CoA hydratase
KHRBS_16360	COG0490	domain, Protein
KHRBS_16365	COG0475	glutathione-regulated potassium exporter activity
KHRBS_16370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHRBS_16375	COG0561	phosphatase activity
KHRBS_16380	COG4335	DNA alkylation repair
KHRBS_16385	COG3679	Belongs to the UPF0342 family
KHRBS_16390	COG4399	Belongs to the UPF0754 family
KHRBS_16395	COG0189	ligase activity
KHRBS_16400	COG0189	ligase activity
KHRBS_16415	COG0702	epimerase
KHRBS_16420	COG1132	(ABC) transporter
KHRBS_16425	COG1132	(ABC) transporter
KHRBS_16435	COG0589	response to stress
KHRBS_16440	COG1757	Na H antiporter
KHRBS_16445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHRBS_16450	COG0726	polysaccharide deacetylase
KHRBS_16455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHRBS_16460	COG0668	transmembrane transport
KHRBS_16470	COG0584	glycerophosphoryl diester phosphodiesterase
KHRBS_16475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHRBS_16480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHRBS_16485	COG1253	flavin adenine dinucleotide binding
KHRBS_16490	COG0436	Aminotransferase
KHRBS_16495	COG0789	Transcriptional regulator
KHRBS_16500	COG1253	flavin adenine dinucleotide binding
KHRBS_16505	COG0204	Acyl-transferase
KHRBS_16510	COG0667	Aldo Keto reductase
KHRBS_16515	COG1595	DNA-templated transcription, initiation
KHRBS_16530	COG0456	acetyltransferase
KHRBS_16535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHRBS_16540	COG0733	neurotransmitter:sodium symporter activity
KHRBS_16550	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_16560	COG0583	DNA-binding transcription factor activity
KHRBS_16565	COG0791	NLP P60 protein
KHRBS_16565	COG1388	LysM domain
KHRBS_16570	COG1785	Belongs to the alkaline phosphatase family
KHRBS_16575	COG2719	SpoVR family
KHRBS_16580	COG0668	transmembrane transport
KHRBS_16585	COG1959	2 iron, 2 sulfur cluster binding
KHRBS_16590	COG1388	LysM domain
KHRBS_16590	COG0791	NLP P60 protein
KHRBS_16605	COG0431	NADPH-dependent FMN reductase
KHRBS_16610	COG2197	response regulator
KHRBS_16620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHRBS_16630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHRBS_16635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHRBS_16640	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KHRBS_16645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHRBS_16650	COG3153	acetyltransferase
KHRBS_16650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHRBS_16655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHRBS_16660	COG0517	IMP dehydrogenase activity
KHRBS_16670	COG0564	pseudouridine synthase activity
KHRBS_16675	COG3764	Sortase (surface protein transpeptidase)
KHRBS_16685	COG5577	PFAM Coat F domain
KHRBS_16705	COG1823	symporter activity
KHRBS_16725	COG1278	Cold shock
KHRBS_16730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHRBS_16735	COG1131	(ABC) transporter
KHRBS_16740	COG1131	(ABC) transporter
KHRBS_16745	COG1725	Transcriptional regulator
KHRBS_16760	COG0655	NAD(P)H dehydrogenase (quinone) activity
KHRBS_16765	COG2814	Major facilitator Superfamily
KHRBS_16770	COG1566	PFAM secretion protein HlyD family protein
KHRBS_16775	COG1846	Transcriptional regulator
KHRBS_16785	COG2718	Belongs to the UPF0229 family
KHRBS_16790	COG2766	serine protein kinase
KHRBS_16795	COG1664	Polymer-forming cytoskeletal
KHRBS_16800	COG1664	Polymer-forming cytoskeletal
KHRBS_16810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KHRBS_16820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHRBS_16825	COG3382	B3 4 domain protein
KHRBS_16835	COG1476	TRANSCRIPTIONal
KHRBS_16845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHRBS_16855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHRBS_16860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHRBS_16865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHRBS_16870	COG1116	anion transmembrane transporter activity
KHRBS_16875	COG0753	catalase activity
KHRBS_16885	COG0277	FAD linked oxidase domain protein
KHRBS_16890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KHRBS_16900	COG5577	PFAM Coat F domain
KHRBS_16910	COG4326	sporulation control protein
KHRBS_17025	COG0735	belongs to the Fur family
KHRBS_17030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHRBS_17035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KHRBS_17040	COG4129	membrane
KHRBS_17045	COG1132	(ABC) transporter
KHRBS_17050	COG3557	Belongs to the UPF0374 family
KHRBS_17065	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_17075	COG1194	a g-specific adenine glycosylase
KHRBS_17080	COG1988	membrane-bound metal-dependent
KHRBS_17085	COG4485	Bacterial membrane protein, YfhO
KHRBS_17090	COG0463	Glycosyl transferase, family 2
KHRBS_17095	COG0596	Alpha beta hydrolase
KHRBS_17100	COG5658	integral membrane protein
KHRBS_17105	COG3103	Sh3 type 3 domain protein
KHRBS_17120	COG2814	Major facilitator Superfamily
KHRBS_17135	COG2137	regulation of response to DNA damage stimulus
KHRBS_17140	COG1090	epimerase
KHRBS_17155	COG0778	Nitroreductase
KHRBS_17160	COG0384	phenazine biosynthesis protein PhzF
KHRBS_17165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_17170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_17175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHRBS_17180	COG0392	lysyltransferase activity
KHRBS_17180	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHRBS_17195	COG2318	DinB family
KHRBS_17200	COG2814	Major facilitator Superfamily
KHRBS_17205	COG1309	transcriptional regulator
KHRBS_17210	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KHRBS_17215	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KHRBS_17220	COG1695	Transcriptional regulator
KHRBS_17225	COG0842	Transport permease protein
KHRBS_17230	COG1511	domain protein
KHRBS_17230	COG0842	Transport permease protein
KHRBS_17235	COG1131	(ABC) transporter
KHRBS_17240	COG2197	response regulator
KHRBS_17245	COG4585	Histidine kinase
KHRBS_17250	COG2514	catechol 2,3-dioxygenase activity
KHRBS_17255	COG2259	Doxx family
KHRBS_17260	COG1132	(ABC) transporter
KHRBS_17265	COG1132	(ABC) transporter
KHRBS_17270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_17270	COG1263	PTS System
KHRBS_17275	COG1737	Transcriptional regulator
KHRBS_17280	COG1486	melibiose metabolic process
KHRBS_17285	COG4842	Belongs to the WXG100 family
KHRBS_17320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHRBS_17325	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHRBS_17330	COG0022	dehydrogenase e1 component
KHRBS_17335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHRBS_17345	COG4637	Psort location Cytoplasmic, score
KHRBS_17360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHRBS_17365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHRBS_17370	COG0598	Magnesium transport protein CorA
KHRBS_17375	COG2084	Dehydrogenase
KHRBS_17380	COG0726	polysaccharide deacetylase
KHRBS_17390	COG0535	radical SAM domain protein
KHRBS_17395	COG0668	transmembrane transport
KHRBS_17405	COG0387	Pfam Sodium calcium exchanger
KHRBS_17415	COG0477	Major facilitator Superfamily
KHRBS_17435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHRBS_17440	COG4840	Belongs to the UPF0435 family
KHRBS_17445	COG2814	Major facilitator Superfamily
KHRBS_17450	COG0693	protein deglycase activity
KHRBS_17455	COG0737	Belongs to the 5'-nucleotidase family
KHRBS_17460	COG0778	Nitroreductase
KHRBS_17465	COG2188	Transcriptional regulator
KHRBS_17470	COG0366	Alpha amylase catalytic
KHRBS_17475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_17475	COG1263	PTS System
KHRBS_17480	COG0697	spore germination
KHRBS_17485	COG0531	amino acid
KHRBS_17490	COG1115	amino acid carrier protein
KHRBS_17505	COG1263	PTS System
KHRBS_17505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_17510	COG0024	Methionine aminopeptidase
KHRBS_17530	COG2258	MOSC domain
KHRBS_17535	COG1254	Belongs to the acylphosphatase family
KHRBS_17540	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KHRBS_17545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHRBS_17550	COG2851	Citrate transporter
KHRBS_17560	COG3181	Tripartite tricarboxylate transporter family receptor
KHRBS_17565	COG4565	transcriptional regulatory protein
KHRBS_17570	COG3290	protein histidine kinase activity
KHRBS_17575	COG0471	metal ion transport
KHRBS_17580	COG3866	Pectate lyase
KHRBS_17595	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KHRBS_17600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_17605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_17610	COG1120	ATPase activity
KHRBS_17620	COG2211	Major facilitator Superfamily
KHRBS_17635	COG2130	NADP-dependent
KHRBS_17640	COG0456	acetyltransferase
KHRBS_17645	COG0513	Belongs to the DEAD box helicase family
KHRBS_17650	COG0488	(ABC) transporter
KHRBS_17665	COG2814	Major facilitator Superfamily
KHRBS_17670	COG0789	Transcriptional regulator
KHRBS_17680	COG0488	(ABC) transporter
KHRBS_17685	COG0840	transmembrane signaling receptor activity
KHRBS_17690	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_17700	COG1011	Hydrolase
KHRBS_17705	COG2223	nitrite transmembrane transporter activity
KHRBS_17710	COG1442	glycosyl transferase family 8
KHRBS_17715	COG1216	Glycosyl transferase, family 2
KHRBS_17725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHRBS_17730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KHRBS_17735	COG1368	sulfuric ester hydrolase activity
KHRBS_17740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHRBS_17740	COG2124	cytochrome p450
KHRBS_17750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHRBS_17755	COG1846	Transcriptional regulator
KHRBS_17760	COG0697	spore germination
KHRBS_17765	COG0670	Belongs to the BI1 family
KHRBS_17770	COG5583	Uncharacterized small protein (DUF2292)
KHRBS_17785	COG0346	lactoylglutathione lyase activity
KHRBS_17790	COG2329	Antibiotic biosynthesis monooxygenase
KHRBS_17795	COG2323	membrane
KHRBS_17800	COG1486	melibiose metabolic process
KHRBS_17805	COG0395	ABC-type sugar transport system, permease component
KHRBS_17810	COG4209	transmembrane transport
KHRBS_17815	COG1653	transport
KHRBS_17825	COG1874	Beta-galactosidase
KHRBS_17840	COG3401	FG-GAP repeat protein
KHRBS_17845	COG5578	integral membrane protein
KHRBS_17855	COG2755	lipolytic protein G-D-S-L family
KHRBS_17860	COG2207	Transcriptional regulator
KHRBS_17865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KHRBS_17870	COG0395	ABC-type sugar transport system, permease component
KHRBS_17875	COG1175	transmembrane transport
KHRBS_17880	COG1653	transport
KHRBS_17885	COG2207	Transcriptional regulator
KHRBS_17885	COG4753	response regulator
KHRBS_17890	COG2972	Histidine kinase
KHRBS_17895	COG5578	integral membrane protein
KHRBS_17905	COG0454	-acetyltransferase
KHRBS_17910	COG3546	catalase activity
KHRBS_17925	COG0702	epimerase
KHRBS_17930	COG3631	Ketosteroid isomerase-related protein
KHRBS_17935	COG1309	transcriptional regulator
KHRBS_17945	COG0217	transcriptional regulatory protein
KHRBS_17970	COG3391	amine dehydrogenase activity
KHRBS_17995	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHRBS_18010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHRBS_18015	COG1597	lipid kinase activity
KHRBS_18025	COG1309	transcriptional regulator
KHRBS_18030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHRBS_18040	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHRBS_18045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHRBS_18050	COG1285	pathogenesis
KHRBS_18055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHRBS_18060	COG4851	CamS sex pheromone cAM373 precursor
KHRBS_18065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHRBS_18075	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KHRBS_18085	COG0069	glutamate synthase activity
KHRBS_18090	COG4496	protein, YerC YecD
KHRBS_18095	COG1470	cell adhesion involved in biofilm formation
KHRBS_18100	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHRBS_18115	COG1522	sequence-specific DNA binding
KHRBS_18120	COG0151	Belongs to the GarS family
KHRBS_18125	COG0138	bifunctional purine biosynthesis protein purh
KHRBS_18130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHRBS_18135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KHRBS_18140	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHRBS_18145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHRBS_18150	COG0047	phosphoribosylformylglycinamidine synthase activity
KHRBS_18155	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHRBS_18160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KHRBS_18165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHRBS_18170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHRBS_18175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHRBS_18185	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KHRBS_18195	COG3064	Membrane
KHRBS_18200	COG2252	PERMEase
KHRBS_18215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KHRBS_18215	COG0519	Catalyzes the synthesis of GMP from XMP
KHRBS_18220	COG1305	Transglutaminase-like
KHRBS_18225	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KHRBS_18230	COG0714	Associated with various cellular activities
KHRBS_18235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHRBS_18245	COG1113	amino acid transport
KHRBS_18250	COG2132	Multicopper oxidase
KHRBS_18260	COG2267	carboxylic ester hydrolase activity
KHRBS_18275	COG0823	Involved in the tonB-independent uptake of proteins
KHRBS_18280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHRBS_18285	COG1063	alcohol dehydrogenase
KHRBS_18290	COG2814	Major facilitator Superfamily
KHRBS_18300	COG4260	virion core protein, lumpy skin disease virus
KHRBS_18305	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KHRBS_18310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHRBS_18315	COG1842	Phage shock protein A
KHRBS_18320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHRBS_18325	COG2211	Major facilitator Superfamily
KHRBS_18330	COG1063	alcohol dehydrogenase
KHRBS_18335	COG0457	Tetratricopeptide repeat
KHRBS_18340	COG1073	alpha beta
KHRBS_18350	COG0459	protein refolding
KHRBS_18355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHRBS_18360	COG1266	CAAX protease self-immunity
KHRBS_18370	COG0805	protein transport
KHRBS_18375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHRBS_18380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHRBS_18385	COG0315	cyclic pyranopterin monophosphate synthase activity
KHRBS_18390	COG0488	(ABC) transporter
KHRBS_18395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHRBS_18400	COG0456	acetyltransferase
KHRBS_18405	COG1214	PFAM Peptidase M22, glycoprotease
KHRBS_18410	COG0802	atpase or kinase
KHRBS_18415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KHRBS_18460	COG4124	Belongs to the glycosyl hydrolase 26 family
KHRBS_18465	COG1482	cell wall glycoprotein biosynthetic process
KHRBS_18470	COG1940	carbohydrate kinase activity
KHRBS_18475	COG2188	Transcriptional regulator
KHRBS_18480	COG2723	6-phospho-beta-galactosidase activity
KHRBS_18490	COG1447	Phosphotransferase system cellobiose-specific component IIA
KHRBS_18495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHRBS_18500	COG2814	Major facilitator Superfamily
KHRBS_18505	COG1388	LysM domain
KHRBS_18510	COG1078	dGTPase activity
KHRBS_18515	COG0454	-acetyltransferase
KHRBS_18525	COG5646	InterPro IPR014922
KHRBS_18530	COG1785	Belongs to the alkaline phosphatase family
KHRBS_18540	COG1819	glycosyl
KHRBS_18550	COG1802	Transcriptional regulator
KHRBS_18555	COG0730	response to heat
KHRBS_18560	COG2814	Major facilitator Superfamily
KHRBS_18565	COG1846	Transcriptional regulator
KHRBS_18570	COG0778	Nitroreductase
KHRBS_18575	COG2409	Drug exporters of the RND superfamily
KHRBS_18575	COG1033	growth of symbiont in host cell
KHRBS_18580	COG1846	Transcriptional regulator
KHRBS_18585	COG2318	DinB family
KHRBS_18590	COG1113	amino acid transport
KHRBS_18600	COG0456	acetyltransferase
KHRBS_18610	COG1309	transcriptional regulator
KHRBS_18625	COG0071	Belongs to the small heat shock protein (HSP20) family
KHRBS_18630	COG2323	membrane
KHRBS_18655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_18660	COG2259	Doxx family
KHRBS_18670	COG0778	Nitroreductase
KHRBS_18675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHRBS_18680	COG0789	Transcriptional regulator
KHRBS_18680	COG4978	Transcriptional regulator
KHRBS_18685	COG1811	Na channel or pump
KHRBS_18690	COG0596	Alpha beta hydrolase
KHRBS_18700	COG2197	response regulator
KHRBS_18705	COG4585	Histidine kinase
KHRBS_18715	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHRBS_18725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHRBS_18730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHRBS_18735	COG0697	spore germination
KHRBS_18740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_18750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KHRBS_18755	COG0640	Transcriptional regulator
KHRBS_18760	COG1309	transcriptional regulator
KHRBS_18765	COG2814	Major facilitator Superfamily
KHRBS_18770	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHRBS_18775	COG1733	regulation of RNA biosynthetic process
KHRBS_18780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHRBS_18785	COG1733	regulation of RNA biosynthetic process
KHRBS_18790	COG3545	Serine hydrolase
KHRBS_18795	COG2030	dehydratase
KHRBS_18800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHRBS_18805	COG0697	spore germination
KHRBS_18815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_18840	COG0477	Major facilitator Superfamily
KHRBS_18845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHRBS_18850	COG3708	Transcriptional regulator
KHRBS_18850	COG2207	Transcriptional regulator
KHRBS_18855	COG0697	spore germination
KHRBS_18860	COG2207	Transcriptional regulator
KHRBS_18860	COG1917	Cupin 2, conserved barrel domain protein
KHRBS_18865	COG0697	spore germination
KHRBS_18870	COG1329	Transcriptional regulator
KHRBS_18875	COG1278	Cold shock
KHRBS_18880	COG0693	protein deglycase activity
KHRBS_18905	COG1476	TRANSCRIPTIONal
KHRBS_18950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_18990	COG3091	SprT-like family
KHRBS_19000	COG2183	response to ionizing radiation
KHRBS_19005	COG2208	phosphoserine phosphatase activity
KHRBS_19010	COG1191	sigma factor activity
KHRBS_19015	COG2172	sigma factor antagonist activity
KHRBS_19020	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_19025	COG2208	phosphoserine phosphatase activity
KHRBS_19030	COG2172	sigma factor antagonist activity
KHRBS_19035	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_19040	COG1366	Belongs to the anti-sigma-factor antagonist family
KHRBS_19045	COG2337	Toxic component of a toxin-antitoxin (TA) module
KHRBS_19050	COG0864	Transcriptional regulator
KHRBS_19065	COG0736	holo-[acyl-carrier-protein] synthase activity
KHRBS_19080	COG3402	PFAM membrane-flanked domain
KHRBS_19085	COG0513	Belongs to the DEAD box helicase family
KHRBS_19090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHRBS_19095	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHRBS_19100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHRBS_19105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHRBS_19120	COG1960	acyl-CoA dehydrogenase activity
KHRBS_19130	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KHRBS_19135	COG1131	(ABC) transporter
KHRBS_19150	COG1301	dicarboxylic acid transport
KHRBS_19155	COG4565	transcriptional regulatory protein
KHRBS_19160	COG3290	protein histidine kinase activity
KHRBS_19170	COG3546	catalase activity
KHRBS_19175	COG2329	Antibiotic biosynthesis monooxygenase
KHRBS_19180	COG0662	Cupin 2, conserved barrel domain protein
KHRBS_19185	COG3729	General stress protein
KHRBS_19190	COG2217	Heavy metal translocating P-type atpase
KHRBS_19195	COG4876	unkown
KHRBS_19200	COG2261	transglycosylase associated protein
KHRBS_19205	COG1914	H( )-stimulated, divalent metal cation uptake system
KHRBS_19215	COG0028	Belongs to the TPP enzyme family
KHRBS_19225	COG0531	amino acid
KHRBS_19240	COG5298	Protein conserved in bacteria
KHRBS_19245	COG3706	GGDEF domain
KHRBS_19250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KHRBS_19255	COG0551	DNA topoisomerase type I activity
KHRBS_19255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHRBS_19260	COG1522	sequence-specific DNA binding
KHRBS_19265	COG2814	Major facilitator Superfamily
KHRBS_19275	COG3871	stress protein (general stress protein 26)
KHRBS_19280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_19290	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_19295	COG2226	methyltransferase
KHRBS_19300	COG0318	PFAM AMP-dependent synthetase and ligase
KHRBS_19305	COG3711	transcriptional antiterminator
KHRBS_19310	COG4989	oxidoreductase activity
KHRBS_19315	COG0768	penicillin binding
KHRBS_19320	COG2329	Antibiotic biosynthesis monooxygenase
KHRBS_19330	COG2755	lipolytic protein G-D-S-L family
KHRBS_19335	COG1414	Transcriptional regulator
KHRBS_19340	COG1984	allophanate hydrolase subunit 2
KHRBS_19345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KHRBS_19350	COG4336	lyase activity
KHRBS_19355	COG1914	H( )-stimulated, divalent metal cation uptake system
KHRBS_19360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KHRBS_19365	COG0561	phosphatase activity
KHRBS_19375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHRBS_19380	COG0412	Dienelactone hydrolase
KHRBS_19390	COG0681	Belongs to the peptidase S26 family
KHRBS_19395	COG0473	3-isopropylmalate dehydrogenase activity
KHRBS_19400	COG0246	Mannitol dehydrogenase
KHRBS_19405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHRBS_19410	COG2213	PTS system mannitol-specific
KHRBS_19420	COG1349	DNA-binding transcription factor activity
KHRBS_19425	COG1276	copper resistance
KHRBS_19425	COG2372	response to copper ion
KHRBS_19430	COG4549	nuclear export factor GLE1
KHRBS_19435	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_19445	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_19450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHRBS_19460	COG0640	Transcriptional regulator
KHRBS_19465	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KHRBS_19470	COG0778	Nitroreductase
KHRBS_19475	COG1309	transcriptional regulator
KHRBS_19480	COG2814	Major facilitator Superfamily
KHRBS_19485	COG4607	ABC-type enterochelin transport system periplasmic component
KHRBS_19490	COG4604	ABC transporter, ATP-binding protein
KHRBS_19495	COG4605	iron ion homeostasis
KHRBS_19500	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_19505	COG0527	aspartate kinase activity
KHRBS_19520	COG0457	Tetratricopeptide repeat
KHRBS_19525	COG3850	Histidine kinase
KHRBS_19525	COG5002	protein histidine kinase activity
KHRBS_19535	COG0577	efflux transmembrane transporter activity
KHRBS_19540	COG1136	(ABC) transporter
KHRBS_19545	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KHRBS_19555	COG0697	spore germination
KHRBS_19565	COG5434	Belongs to the glycosyl hydrolase 28 family
KHRBS_19570	COG3104	oligopeptide transport
KHRBS_19575	COG0596	Alpha beta hydrolase
KHRBS_19590	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KHRBS_19595	COG0163	prenyltransferase activity
KHRBS_19600	COG0583	DNA-binding transcription factor activity
KHRBS_19605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHRBS_19610	COG0765	amino acid transport
KHRBS_19615	COG1126	abc transporter atp-binding protein
KHRBS_19620	COG2364	Membrane
KHRBS_19630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHRBS_19635	COG0697	spore germination
KHRBS_19645	COG2814	Major facilitator Superfamily
KHRBS_19650	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KHRBS_19655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_19665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHRBS_19675	COG1733	regulation of RNA biosynthetic process
KHRBS_19680	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KHRBS_19685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KHRBS_19690	COG3290	protein histidine kinase activity
KHRBS_19690	COG0840	transmembrane signaling receptor activity
KHRBS_19695	COG3209	COG3209 Rhs family protein
KHRBS_19705	COG2723	6-phospho-beta-galactosidase activity
KHRBS_19715	COG1714	RDD family
KHRBS_19730	COG0765	amino acid transport
KHRBS_19735	COG0523	cobalamin synthesis protein
KHRBS_19745	COG1376	ErfK ybiS ycfS ynhG family protein
KHRBS_19765	COG0243	molybdopterin cofactor binding
KHRBS_19770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHRBS_19775	COG2146	nitrite reductase [NAD(P)H] activity
KHRBS_19780	COG1587	Uroporphyrinogen-III synthase
KHRBS_19780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHRBS_19785	COG0492	ferredoxin-NADP+ reductase activity
KHRBS_19790	COG2267	carboxylic ester hydrolase activity
KHRBS_19795	COG0701	Predicted permease
KHRBS_19800	COG3689	TIGRFAM TIGR03943 family protein
KHRBS_19805	COG2508	Transcriptional regulator
KHRBS_19810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHRBS_19815	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_19820	COG0506	proline dehydrogenase activity
KHRBS_19825	COG3541	Predicted nucleotidyltransferase
KHRBS_19830	COG3458	cephalosporin-C deacetylase activity
KHRBS_19835	COG0583	DNA-binding transcription factor activity
KHRBS_19840	COG2226	methyltransferase
KHRBS_19845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHRBS_19850	COG1660	Displays ATPase and GTPase activities
KHRBS_19855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KHRBS_19860	COG3665	Urea carboxylase-associated protein
KHRBS_19870	COG3403	YqcI/YcgG family
KHRBS_19880	COG1846	Transcriptional regulator
KHRBS_19885	COG2814	Major facilitator Superfamily
KHRBS_19890	COG1620	l-lactate permease
KHRBS_19895	COG0039	L-malate dehydrogenase activity
KHRBS_19900	COG0366	Alpha amylase catalytic
KHRBS_19915	COG1288	antiporter activity
KHRBS_19920	COG1473	amidohydrolase
KHRBS_19925	COG2113	Glycine betaine
KHRBS_19930	COG4176	ABC-type proline glycine betaine transport system permease component
KHRBS_19935	COG4175	Glycine betaine
KHRBS_19935	COG0517	IMP dehydrogenase activity
KHRBS_19940	COG0640	Transcriptional regulator
KHRBS_19945	COG2814	Major facilitator Superfamily
KHRBS_19950	COG0477	Major facilitator Superfamily
KHRBS_19955	COG3853	Toxic anion resistance protein (TelA)
KHRBS_19965	COG0861	Integral membrane protein TerC family
KHRBS_19970	COG2310	stress, protein
KHRBS_19975	COG2310	stress, protein
KHRBS_19980	COG2310	stress, protein
KHRBS_19985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHRBS_19990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHRBS_19995	COG1121	(ABC) transporter
KHRBS_20000	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHRBS_20005	COG0366	Alpha amylase catalytic
KHRBS_20010	COG1028	Short-chain dehydrogenase reductase Sdr
KHRBS_20025	COG1595	DNA-templated transcription, initiation
KHRBS_20030	COG1595	DNA-templated transcription, initiation
KHRBS_20040	COG0667	Aldo Keto reductase
KHRBS_20045	COG1668	transmembrane transport
KHRBS_20050	COG4555	ABC transporter
KHRBS_20055	COG3279	Response regulator of the LytR AlgR family
KHRBS_20060	COG3290	protein histidine kinase activity
KHRBS_20065	COG3012	SEC-C Motif Domain Protein
KHRBS_20065	COG1405	negative regulation of cell septum assembly
KHRBS_20070	COG1714	RDD family
KHRBS_20075	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KHRBS_20080	COG0252	asparaginase activity
KHRBS_20085	COG1309	transcriptional regulator
KHRBS_20090	COG0477	Major facilitator Superfamily
KHRBS_20095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHRBS_20100	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHRBS_20105	COG0805	protein transport
KHRBS_20110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHRBS_20115	COG3540	Alkaline phosphatase
KHRBS_20125	COG2304	oxidoreductase activity
KHRBS_20130	COG3773	Cell wall hydrolase
KHRBS_20150	COG1131	(ABC) transporter
KHRBS_20155	COG2205	protein histidine kinase activity
KHRBS_20160	COG0745	RESPONSE REGULATOR receiver
KHRBS_20175	COG3173	Aminoglycoside phosphotransferase
KHRBS_20180	COG2721	sulfolactate sulfo-lyase activity
KHRBS_20190	COG4948	Mandelate Racemase Muconate Lactonizing
KHRBS_20195	COG2271	Major facilitator Superfamily
KHRBS_20200	COG1012	belongs to the aldehyde dehydrogenase family
KHRBS_20205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHRBS_20210	COG0784	Response regulator, receiver
KHRBS_20215	COG4191	Histidine kinase
KHRBS_20220	COG2066	Belongs to the glutaminase family
KHRBS_20225	COG1115	amino acid carrier protein
KHRBS_20235	COG2040	homocysteine
KHRBS_20260	COG0363	glucosamine-6-phosphate deaminase activity
KHRBS_20265	COG1263	PTS System
KHRBS_20265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_20265	COG2190	(PTS) system
KHRBS_20290	COG0688	phosphatidylethanolamine metabolic process
KHRBS_20295	COG0586	Pfam SNARE associated Golgi protein
KHRBS_20300	COG1183	phosphatidylcholine synthase activity
KHRBS_20305	COG0596	Alpha beta hydrolase
KHRBS_20320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHRBS_20325	COG1917	Cupin 2, conserved barrel domain protein
KHRBS_20325	COG2207	Transcriptional regulator
KHRBS_20330	COG0697	spore germination
KHRBS_20335	COG3409	Peptidoglycan-binding domain 1 protein
KHRBS_20345	COG2271	Major facilitator Superfamily
KHRBS_20350	COG1846	Transcriptional regulator
KHRBS_20350	COG0456	acetyltransferase
KHRBS_20360	COG2271	Major facilitator Superfamily
KHRBS_20365	COG0584	glycerophosphoryl diester phosphodiesterase
KHRBS_20370	COG0531	amino acid
KHRBS_20385	COG2602	Beta-lactamase
KHRBS_20400	COG1113	amino acid transport
KHRBS_20415	COG0515	serine threonine protein kinase
KHRBS_20425	COG0642	Histidine kinase
KHRBS_20430	COG0745	RESPONSE REGULATOR receiver
KHRBS_20435	COG0596	Alpha beta hydrolase
KHRBS_20445	COG1413	lyase activity
KHRBS_20455	COG1131	(ABC) transporter
KHRBS_20460	COG1266	CAAX protease self-immunity
KHRBS_20465	COG0535	radical SAM domain protein
KHRBS_20485	COG0640	Transcriptional regulator
KHRBS_20490	COG5609	conserved protein (DUF2294)
KHRBS_20500	COG0288	reversible hydration of carbon dioxide
KHRBS_20505	COG3002	Belongs to the UPF0753 family
KHRBS_20520	COG2169	Transcriptional regulator
KHRBS_20525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHRBS_20530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHRBS_20535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHRBS_20540	COG4856	YbbR-like protein
KHRBS_20545	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHRBS_20550	COG5662	AntiSigma factor
KHRBS_20555	COG1595	DNA-templated transcription, initiation
KHRBS_20585	COG1683	Conserved Protein
KHRBS_20590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHRBS_20595	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHRBS_20600	COG1737	Transcriptional regulator
KHRBS_20605	COG1263	PTS System
KHRBS_20605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHRBS_20610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KHRBS_20615	COG1472	Belongs to the glycosyl hydrolase 3 family
KHRBS_20620	COG3876	Protein conserved in bacteria
KHRBS_20625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KHRBS_20625	COG2207	Transcriptional regulator
KHRBS_20635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_20640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHRBS_20645	COG2819	hydrolase of the alpha beta superfamily
KHRBS_20650	COG0385	Bile acid
KHRBS_20655	COG0659	secondary active sulfate transmembrane transporter activity
KHRBS_20740	COG0726	polysaccharide deacetylase
KHRBS_20745	COG2194	sulfuric ester hydrolase activity
KHRBS_20755	COG0489	protein tyrosine kinase activity
KHRBS_20760	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHRBS_20770	COG2226	methyltransferase
KHRBS_20775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KHRBS_20780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHRBS_20790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHRBS_20800	COG1122	ATPase activity
KHRBS_20805	COG0203	ribosomal protein L17
KHRBS_20815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHRBS_20820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHRBS_20825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHRBS_20830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHRBS_20835	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KHRBS_20840	COG0024	Methionine aminopeptidase
KHRBS_20845	COG0563	adenylate kinase activity
KHRBS_20850	COG0201	protein transport
KHRBS_20855	COG0200	Binds to the 23S rRNA
KHRBS_20860	COG1841	ribosomal large subunit assembly
KHRBS_20865	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHRBS_20870	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHRBS_20875	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHRBS_20880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHRBS_20890	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHRBS_20900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHRBS_20905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHRBS_20910	COG0255	Belongs to the universal ribosomal protein uL29 family
KHRBS_20915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHRBS_20920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHRBS_20925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHRBS_20930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHRBS_20935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHRBS_20940	COG0089	rRNA binding
KHRBS_20945	COG0088	Forms part of the polypeptide exit tunnel
KHRBS_20950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHRBS_20955	COG0051	transcription antitermination factor activity, RNA binding
KHRBS_20965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHRBS_20970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHRBS_20980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHRBS_20985	COG1358	cellular component organization or biogenesis
KHRBS_20990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHRBS_20995	COG0085	RNA polymerase activity
KHRBS_21000	COG2813	Specifically methylates the guanine in position
KHRBS_21005	COG0222	ribosome binding
KHRBS_21010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHRBS_21015	COG0081	regulation of translation
KHRBS_21020	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHRBS_21025	COG0250	Participates in transcription elongation, termination and antitermination
KHRBS_21030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHRBS_21035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHRBS_21040	COG1595	DNA-templated transcription, initiation
KHRBS_21045	COG3688	RNA-binding protein containing a PIN domain
KHRBS_21050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHRBS_21055	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHRBS_21060	COG0215	cysteine-tRNA ligase activity
KHRBS_21075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHRBS_21080	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KHRBS_21085	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KHRBS_21090	COG4956	integral membrane protein (PIN domain superfamily)
KHRBS_21095	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KHRBS_21100	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHRBS_21105	COG0542	response to heat
KHRBS_21110	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KHRBS_21115	COG3880	PFAM UvrB UvrC protein
KHRBS_21120	COG4463	regulation of RNA biosynthetic process
KHRBS_21200	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KHRBS_21205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHRBS_21210	COG1396	sequence-specific DNA binding
KHRBS_21215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KHRBS_21220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHRBS_21225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHRBS_21235	COG0512	Glutamine amidotransferase of anthranilate synthase
KHRBS_21240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHRBS_21245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHRBS_21250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHRBS_21255	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHRBS_21260	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHRBS_21265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHRBS_21275	COG0037	tRNA processing
KHRBS_21285	COG2304	oxidoreductase activity
KHRBS_21290	COG2208	phosphoserine phosphatase activity
KHRBS_21305	COG1098	S1 RNA binding domain
KHRBS_21310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KHRBS_21325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KHRBS_21335	COG2244	polysaccharide biosynthetic process
KHRBS_21340	COG2002	toxin-antitoxin pair type II binding
KHRBS_21345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHRBS_21355	COG0193	aminoacyl-tRNA hydrolase activity
KHRBS_21360	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KHRBS_21365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHRBS_21370	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHRBS_21380	COG2088	sporulation resulting in formation of a cellular spore
KHRBS_21385	COG0251	oxidation-reduction process
KHRBS_21390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHRBS_21395	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHRBS_21405	COG4466	Protein conserved in bacteria
KHRBS_21415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHRBS_21420	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHRBS_21425	COG3584	3D domain protein
KHRBS_21425	COG3583	domain protein
KHRBS_21435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHRBS_21435	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHRBS_21440	COG2002	toxin-antitoxin pair type II binding
KHRBS_21445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHRBS_21450	COG2827	Endonuclease containing a URI domain
KHRBS_21455	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KHRBS_21460	COG4467	Involved in initiation control of chromosome replication
KHRBS_21465	COG1774	PSP1 C-terminal conserved region
KHRBS_21470	COG0470	DNA polymerase III
KHRBS_21475	COG1728	Protein conserved in bacteria
KHRBS_21480	COG3870	Protein conserved in bacteria
KHRBS_21485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHRBS_21490	COG1982	Orn Lys Arg decarboxylase major
KHRBS_21500	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KHRBS_21550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHRBS_21555	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHRBS_21565	COG0590	tRNA wobble adenosine to inosine editing
KHRBS_21575	COG3858	chitin binding
KHRBS_21575	COG1388	LysM domain
KHRBS_21580	COG1428	Deoxynucleoside kinase
KHRBS_21585	COG1428	Deoxynucleoside kinase
KHRBS_21595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHRBS_21605	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KHRBS_21610	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KHRBS_21615	COG1686	Belongs to the peptidase S11 family
KHRBS_21620	COG0516	GMP reductase activity
KHRBS_21620	COG0517	IMP dehydrogenase activity
KHRBS_21655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHRBS_21660	COG0187	DNA topoisomerase II activity
KHRBS_21670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHRBS_21675	COG2501	S4 domain
KHRBS_21680	COG0592	DNA-directed DNA polymerase activity