locus-tag	class	description
AS891_00010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_00020	COG1733	regulation of RNA biosynthetic process
AS891_00025	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AS891_00030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AS891_00035	COG0840	transmembrane signaling receptor activity
AS891_00035	COG3290	protein histidine kinase activity
AS891_00040	COG3209	COG3209 Rhs family protein
AS891_00050	COG2723	6-phospho-beta-galactosidase activity
AS891_00060	COG1714	RDD family
AS891_00070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_00075	COG0765	amino acid transport
AS891_00080	COG0523	cobalamin synthesis protein
AS891_00090	COG1376	ErfK ybiS ycfS ynhG family protein
AS891_00095	COG1469	GTP cyclohydrolase I activity
AS891_00100	COG2223	nitrite transmembrane transporter activity
AS891_00105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS891_00110	COG0243	molybdopterin cofactor binding
AS891_00115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS891_00120	COG2146	nitrite reductase [NAD(P)H] activity
AS891_00125	COG1587	Uroporphyrinogen-III synthase
AS891_00125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS891_00130	COG0492	ferredoxin-NADP+ reductase activity
AS891_00135	COG2267	carboxylic ester hydrolase activity
AS891_00140	COG0701	Predicted permease
AS891_00145	COG3689	TIGRFAM TIGR03943 family protein
AS891_00150	COG2508	Transcriptional regulator
AS891_00155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_00160	COG1012	belongs to the aldehyde dehydrogenase family
AS891_00165	COG0506	proline dehydrogenase activity
AS891_00170	COG3541	Predicted nucleotidyltransferase
AS891_00175	COG3458	cephalosporin-C deacetylase activity
AS891_00180	COG0583	DNA-binding transcription factor activity
AS891_00185	COG2226	methyltransferase
AS891_00190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS891_00195	COG1660	Displays ATPase and GTPase activities
AS891_00200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AS891_00205	COG3665	Urea carboxylase-associated protein
AS891_00210	COG1113	amino acid transport
AS891_00215	COG3403	YqcI/YcgG family
AS891_00220	COG1280	lysine exporter protein (LysE YggA)
AS891_00225	COG1846	Transcriptional regulator
AS891_00230	COG2814	Major facilitator Superfamily
AS891_00235	COG1620	l-lactate permease
AS891_00240	COG0039	L-malate dehydrogenase activity
AS891_00245	COG0366	Alpha amylase catalytic
AS891_00260	COG1288	antiporter activity
AS891_00265	COG1473	amidohydrolase
AS891_00270	COG2113	Glycine betaine
AS891_00275	COG4176	ABC-type proline glycine betaine transport system permease component
AS891_00280	COG4175	Glycine betaine
AS891_00280	COG0517	IMP dehydrogenase activity
AS891_00285	COG0640	Transcriptional regulator
AS891_00290	COG2814	Major facilitator Superfamily
AS891_00295	COG0477	Major facilitator Superfamily
AS891_00300	COG3853	Toxic anion resistance protein (TelA)
AS891_00310	COG0861	Integral membrane protein TerC family
AS891_00315	COG2310	stress, protein
AS891_00320	COG2310	stress, protein
AS891_00325	COG2310	stress, protein
AS891_00330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_00335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS891_00340	COG1121	(ABC) transporter
AS891_00345	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS891_00350	COG0366	Alpha amylase catalytic
AS891_00355	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_00360	COG0457	Tetratricopeptide repeat
AS891_00365	COG1876	peptidase activity
AS891_00370	COG1595	DNA-templated transcription, initiation
AS891_00375	COG1595	DNA-templated transcription, initiation
AS891_00385	COG0667	Aldo Keto reductase
AS891_00390	COG1668	transmembrane transport
AS891_00395	COG4555	ABC transporter
AS891_00400	COG3279	Response regulator of the LytR AlgR family
AS891_00405	COG3290	protein histidine kinase activity
AS891_00410	COG3012	SEC-C Motif Domain Protein
AS891_00410	COG1405	negative regulation of cell septum assembly
AS891_00415	COG1714	RDD family
AS891_00420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AS891_00425	COG0252	asparaginase activity
AS891_00430	COG1309	transcriptional regulator
AS891_00435	COG0477	Major facilitator Superfamily
AS891_00440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS891_00445	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AS891_00450	COG0805	protein transport
AS891_00455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS891_00460	COG3540	Alkaline phosphatase
AS891_00470	COG2304	oxidoreductase activity
AS891_00475	COG3773	Cell wall hydrolase
AS891_00495	COG1131	(ABC) transporter
AS891_00500	COG2205	protein histidine kinase activity
AS891_00505	COG0745	RESPONSE REGULATOR receiver
AS891_00510	COG0697	spore germination
AS891_00520	COG3173	Aminoglycoside phosphotransferase
AS891_00525	COG2721	sulfolactate sulfo-lyase activity
AS891_00530	COG2186	Transcriptional regulator
AS891_00535	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_00540	COG2271	Major facilitator Superfamily
AS891_00545	COG1012	belongs to the aldehyde dehydrogenase family
AS891_00550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS891_00555	COG0784	Response regulator, receiver
AS891_00560	COG4191	Histidine kinase
AS891_00565	COG2066	Belongs to the glutaminase family
AS891_00570	COG1115	amino acid carrier protein
AS891_00580	COG2040	homocysteine
AS891_00585	COG0833	amino acid
AS891_00590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_00605	COG0363	glucosamine-6-phosphate deaminase activity
AS891_00610	COG1263	PTS System
AS891_00610	COG2190	(PTS) system
AS891_00610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_00615	COG1301	dicarboxylic acid transport
AS891_00625	COG2207	Transcriptional regulator
AS891_00630	COG2312	Erythromycin esterase
AS891_00640	COG0688	phosphatidylethanolamine metabolic process
AS891_00645	COG0586	Pfam SNARE associated Golgi protein
AS891_00650	COG1183	phosphatidylcholine synthase activity
AS891_00655	COG0596	Alpha beta hydrolase
AS891_00665	COG3591	Belongs to the peptidase S1B family
AS891_00670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AS891_00675	COG1917	Cupin 2, conserved barrel domain protein
AS891_00675	COG2207	Transcriptional regulator
AS891_00680	COG0697	spore germination
AS891_00685	COG3409	Peptidoglycan-binding domain 1 protein
AS891_00700	COG2271	Major facilitator Superfamily
AS891_00705	COG0456	acetyltransferase
AS891_00705	COG1846	Transcriptional regulator
AS891_00715	COG2271	Major facilitator Superfamily
AS891_00720	COG0584	glycerophosphoryl diester phosphodiesterase
AS891_00725	COG0531	amino acid
AS891_00735	COG2124	cytochrome p450
AS891_00740	COG2602	Beta-lactamase
AS891_00755	COG1113	amino acid transport
AS891_00770	COG0515	serine threonine protein kinase
AS891_00780	COG0642	Histidine kinase
AS891_00785	COG0745	RESPONSE REGULATOR receiver
AS891_00790	COG0596	Alpha beta hydrolase
AS891_00795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_00800	COG1413	lyase activity
AS891_00810	COG1131	(ABC) transporter
AS891_00815	COG1266	CAAX protease self-immunity
AS891_00820	COG0535	radical SAM domain protein
AS891_00830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS891_00835	COG2814	Major facilitator Superfamily
AS891_00840	COG0640	Transcriptional regulator
AS891_00850	COG5609	conserved protein (DUF2294)
AS891_00860	COG0288	reversible hydration of carbon dioxide
AS891_00865	COG3002	Belongs to the UPF0753 family
AS891_00870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS891_00875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS891_00880	COG2169	Transcriptional regulator
AS891_00885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS891_00890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AS891_00895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS891_00900	COG4856	YbbR-like protein
AS891_00905	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS891_00910	COG5662	AntiSigma factor
AS891_00915	COG1595	DNA-templated transcription, initiation
AS891_00945	COG1683	Conserved Protein
AS891_00950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_00955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AS891_00960	COG1737	Transcriptional regulator
AS891_00965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_00965	COG1263	PTS System
AS891_00970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS891_00975	COG1472	Belongs to the glycosyl hydrolase 3 family
AS891_00980	COG3876	Protein conserved in bacteria
AS891_00985	COG2207	Transcriptional regulator
AS891_00985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_00990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_00995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_01000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_01005	COG2819	hydrolase of the alpha beta superfamily
AS891_01010	COG0385	Bile acid
AS891_01015	COG0659	secondary active sulfate transmembrane transporter activity
AS891_01100	COG0726	polysaccharide deacetylase
AS891_01105	COG2194	sulfuric ester hydrolase activity
AS891_01115	COG0489	protein tyrosine kinase activity
AS891_01120	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_01130	COG2226	methyltransferase
AS891_01135	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AS891_01140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AS891_01145	COG0101	tRNA pseudouridine synthase activity
AS891_01150	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS891_01155	COG1122	ATPase activity
AS891_01160	COG1122	ATPase activity
AS891_01165	COG0203	ribosomal protein L17
AS891_01170	COG0202	RNA polymerase activity
AS891_01175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AS891_01180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AS891_01185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS891_01190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AS891_01195	COG2163	COG2163 Ribosomal protein L14E L6E L27E
AS891_01200	COG0024	Methionine aminopeptidase
AS891_01205	COG0563	adenylate kinase activity
AS891_01210	COG0201	protein transport
AS891_01215	COG0200	Binds to the 23S rRNA
AS891_01220	COG1841	ribosomal large subunit assembly
AS891_01225	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AS891_01230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AS891_01235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AS891_01240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AS891_01250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS891_01260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AS891_01265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AS891_01270	COG0255	Belongs to the universal ribosomal protein uL29 family
AS891_01275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AS891_01280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AS891_01285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AS891_01290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AS891_01295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AS891_01300	COG0089	rRNA binding
AS891_01305	COG0088	Forms part of the polypeptide exit tunnel
AS891_01310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AS891_01315	COG0051	transcription antitermination factor activity, RNA binding
AS891_01320	COG0596	Alpha beta hydrolase
AS891_01325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AS891_01330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AS891_01335	COG0049	tRNA binding
AS891_01340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AS891_01345	COG1358	cellular component organization or biogenesis
AS891_01350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AS891_01355	COG0085	RNA polymerase activity
AS891_01360	COG2813	Specifically methylates the guanine in position
AS891_01365	COG0222	ribosome binding
AS891_01370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AS891_01375	COG0081	regulation of translation
AS891_01380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AS891_01385	COG0250	Participates in transcription elongation, termination and antitermination
AS891_01390	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS891_01395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS891_01400	COG1595	DNA-templated transcription, initiation
AS891_01405	COG3688	RNA-binding protein containing a PIN domain
AS891_01410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS891_01415	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AS891_01420	COG0215	cysteine-tRNA ligase activity
AS891_01425	COG1045	serine acetyltransferase
AS891_01435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AS891_01440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AS891_01445	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AS891_01450	COG4956	integral membrane protein (PIN domain superfamily)
AS891_01455	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AS891_01460	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS891_01465	COG0542	response to heat
AS891_01470	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AS891_01475	COG3880	PFAM UvrB UvrC protein
AS891_01480	COG4463	regulation of RNA biosynthetic process
AS891_01565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AS891_01570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS891_01575	COG1396	sequence-specific DNA binding
AS891_01580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS891_01585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS891_01590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS891_01595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_01600	COG0512	Glutamine amidotransferase of anthranilate synthase
AS891_01605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS891_01610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS891_01615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS891_01620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AS891_01625	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AS891_01630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS891_01640	COG0037	tRNA processing
AS891_01645	COG0515	serine threonine protein kinase
AS891_01650	COG2304	oxidoreductase activity
AS891_01655	COG2208	phosphoserine phosphatase activity
AS891_01670	COG1098	S1 RNA binding domain
AS891_01675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AS891_01690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS891_01695	COG3956	TIGRFAM MazG family protein
AS891_01700	COG2244	polysaccharide biosynthetic process
AS891_01705	COG2002	toxin-antitoxin pair type II binding
AS891_01710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AS891_01720	COG0193	aminoacyl-tRNA hydrolase activity
AS891_01725	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AS891_01730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS891_01735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AS891_01745	COG2088	sporulation resulting in formation of a cellular spore
AS891_01750	COG0251	oxidation-reduction process
AS891_01755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS891_01760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AS891_01770	COG4466	Protein conserved in bacteria
AS891_01780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AS891_01785	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS891_01790	COG3584	3D domain protein
AS891_01790	COG3583	domain protein
AS891_01795	COG0084	hydrolase, TatD family'
AS891_01800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_01800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_01805	COG2002	toxin-antitoxin pair type II binding
AS891_01810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AS891_01815	COG2827	Endonuclease containing a URI domain
AS891_01820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AS891_01825	COG4467	Involved in initiation control of chromosome replication
AS891_01830	COG1774	PSP1 C-terminal conserved region
AS891_01835	COG0470	DNA polymerase III
AS891_01840	COG1728	Protein conserved in bacteria
AS891_01845	COG3870	Protein conserved in bacteria
AS891_01850	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS891_01855	COG1982	Orn Lys Arg decarboxylase major
AS891_01860	COG3853	Toxic anion resistance protein (TelA)
AS891_01865	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AS891_01910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AS891_01915	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AS891_01920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS891_01930	COG0590	tRNA wobble adenosine to inosine editing
AS891_01935	COG1335	isochorismatase
AS891_01940	COG3858	chitin binding
AS891_01940	COG1388	LysM domain
AS891_01945	COG1428	Deoxynucleoside kinase
AS891_01950	COG1428	Deoxynucleoside kinase
AS891_01960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AS891_01965	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AS891_01970	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AS891_01975	COG1686	Belongs to the peptidase S11 family
AS891_01980	COG0517	IMP dehydrogenase activity
AS891_01980	COG0516	GMP reductase activity
AS891_02015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS891_02020	COG0187	DNA topoisomerase II activity
AS891_02030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AS891_02035	COG2501	S4 domain
AS891_02040	COG0592	DNA-directed DNA polymerase activity
AS891_02045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AS891_02050	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AS891_02055	COG0594	ribonuclease P activity
AS891_02060	COG0706	membrane insertase activity
AS891_02065	COG1847	R3H domain protein
AS891_02070	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AS891_02075	COG0445	tRNA wobble uridine modification
AS891_02080	COG0357	Ribosomal RNA small subunit methyltransferase G
AS891_02085	COG1475	DNA binding
AS891_02095	COG1192	Involved in chromosome partitioning
AS891_02100	COG1475	DNA binding
AS891_02110	COG3949	Membrane
AS891_02115	COG4481	Protein conserved in bacteria
AS891_02120	COG0243	molybdopterin cofactor binding
AS891_02125	COG0012	GTP binding
AS891_02130	COG0360	Binds together with S18 to 16S ribosomal RNA
AS891_02135	COG0629	single-stranded DNA binding
AS891_02140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AS891_02145	COG0708	Exodeoxyribonuclease III
AS891_02150	COG1609	Transcriptional regulator
AS891_02155	COG0346	lactoylglutathione lyase activity
AS891_02160	COG0110	maltose O-acetyltransferase activity
AS891_02165	COG2814	Major facilitator Superfamily
AS891_02165	COG0477	Major facilitator Superfamily
AS891_02170	COG1266	CAAX protease self-immunity
AS891_02175	COG1331	Highly conserved protein containing a thioredoxin domain
AS891_02180	COG0697	spore germination
AS891_02185	COG0789	Transcriptional regulator
AS891_02190	COG1331	Highly conserved protein containing a thioredoxin domain
AS891_02195	COG2814	Major facilitator Superfamily
AS891_02200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS891_02205	COG2315	Protein conserved in bacteria
AS891_02210	COG0456	acetyltransferase
AS891_02215	COG2364	Membrane
AS891_02220	COG2153	protein acetylation
AS891_02225	COG1846	Transcriptional regulator
AS891_02230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_02240	COG2153	protein acetylation
AS891_02245	COG0583	DNA-binding transcription factor activity
AS891_02250	COG2814	Major facilitator Superfamily
AS891_02255	COG1357	PFAM Pentapeptide repeats (8 copies)
AS891_02260	COG4319	ketosteroid isomerase
AS891_02270	COG1131	(ABC) transporter
AS891_02300	COG4319	ketosteroid isomerase
AS891_02310	COG2271	Major facilitator Superfamily
AS891_02325	COG1227	inorganic diphosphatase activity
AS891_02330	COG1733	regulation of RNA biosynthetic process
AS891_02335	COG5577	PFAM Coat F domain
AS891_02345	COG4241	membrane
AS891_02350	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AS891_02355	COG0359	binds to the 23S rRNA
AS891_02360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS891_02365	COG2807	transmembrane transport
AS891_02370	COG3093	addiction module antidote protein HigA
AS891_02390	COG0305	Participates in initiation and elongation during chromosome replication
AS891_02395	COG0346	lactoylglutathione lyase activity
AS891_02425	COG0745	RESPONSE REGULATOR receiver
AS891_02430	COG5002	protein histidine kinase activity
AS891_02435	COG4863	YycH protein
AS891_02440	COG4853	Protein conserved in bacteria
AS891_02445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS891_02450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_02460	COG5002	protein histidine kinase activity
AS891_02465	COG3829	transcription factor binding
AS891_02470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS891_02475	COG0833	amino acid
AS891_02480	COG0010	Belongs to the arginase family
AS891_02490	COG0457	Tetratricopeptide repeat
AS891_02495	COG0456	acetyltransferase
AS891_02500	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AS891_02520	COG1063	alcohol dehydrogenase
AS891_02530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AS891_02535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS891_02545	COG5293	efflux transmembrane transporter activity
AS891_02550	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AS891_02560	COG0535	radical SAM domain protein
AS891_02565	COG1994	Peptidase M50
AS891_02570	COG1131	(ABC) transporter
AS891_02585	COG2188	Transcriptional regulator
AS891_02590	COG2190	(PTS) system
AS891_02595	COG2723	6-phospho-beta-galactosidase activity
AS891_02600	COG3634	alkyl hydroperoxide reductase activity
AS891_02605	COG0450	alkyl hydroperoxide reductase
AS891_02610	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS891_02615	COG2610	gluconate transmembrane transporter activity
AS891_02620	COG1070	Carbohydrate kinase
AS891_02625	COG1802	Transcriptional regulator
AS891_02630	COG1929	Belongs to the glycerate kinase type-1 family
AS891_02635	COG5039	Polysaccharide pyruvyl transferase
AS891_02640	COG1346	cytolysis
AS891_02645	COG1380	Effector of murein hydrolase LrgA
AS891_02650	COG1846	Transcriptional regulator
AS891_02655	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_02660	COG1309	transcriptional regulator
AS891_02665	COG1917	Cupin 2, conserved barrel domain protein
AS891_02670	COG2311	Membrane
AS891_02675	COG1714	RDD family
AS891_02685	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS891_02690	COG2814	Major facilitator Superfamily
AS891_02695	COG0367	asparagine synthase
AS891_02710	COG2226	methyltransferase
AS891_02715	COG2850	peptidyl-arginine hydroxylation
AS891_02720	COG0456	acetyltransferase
AS891_02725	COG1012	belongs to the aldehyde dehydrogenase family
AS891_02730	COG1309	transcriptional regulator
AS891_02735	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_02745	COG0326	Molecular chaperone. Has ATPase activity
AS891_02750	COG2814	Major facilitator Superfamily
AS891_02765	COG0667	Aldo Keto reductase
AS891_02770	COG1349	DNA-binding transcription factor activity
AS891_02775	COG1012	belongs to the aldehyde dehydrogenase family
AS891_02780	COG3718	enzyme involved in inositol metabolism
AS891_02785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_02790	COG3962	Belongs to the TPP enzyme family
AS891_02795	COG1082	Xylose isomerase domain protein TIM barrel
AS891_02800	COG2814	Major facilitator Superfamily
AS891_02805	COG0673	inositol 2-dehydrogenase activity
AS891_02810	COG1082	Xylose isomerase domain protein TIM barrel
AS891_02815	COG1082	Xylose isomerase domain protein TIM barrel
AS891_02820	COG0191	fructose-bisphosphate aldolase activity
AS891_02825	COG0745	RESPONSE REGULATOR receiver
AS891_02830	COG2205	protein histidine kinase activity
AS891_02835	COG1136	(ABC) transporter
AS891_02840	COG0577	efflux transmembrane transporter activity
AS891_02845	COG5294	Protein conserved in bacteria
AS891_02850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_02880	COG0561	phosphatase activity
AS891_02885	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AS891_02905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_02910	COG0765	amino acid transport
AS891_02915	COG1126	abc transporter atp-binding protein
AS891_02925	COG2079	MmgE PrpD family protein
AS891_02930	COG3192	ethanolamine utilization protein
AS891_02940	COG2390	Transcriptional regulator
AS891_02945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AS891_02950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS891_02955	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AS891_02960	COG0833	amino acid
AS891_02965	COG0010	Belongs to the arginase family
AS891_02970	COG1228	amidohydrolase
AS891_02975	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AS891_02980	COG2986	histidine ammonia-lyase
AS891_02995	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_03010	COG5444	nuclease activity
AS891_03025	COG1263	PTS System
AS891_03025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_03025	COG2190	(PTS) system
AS891_03030	COG2723	6-phospho-beta-galactosidase activity
AS891_03035	COG0589	response to stress
AS891_03040	COG0697	spore germination
AS891_03045	COG3209	COG3209 Rhs family protein
AS891_03100	COG3401	FG-GAP repeat protein
AS891_03100	COG2755	lipolytic protein G-D-S-L family
AS891_03105	COG0513	Belongs to the DEAD box helicase family
AS891_03110	COG2270	Major facilitator Superfamily
AS891_03120	COG3711	transcriptional antiterminator
AS891_03125	COG2273	Hydrolase Family 16
AS891_03130	COG2851	Citrate transporter
AS891_03135	COG0753	catalase activity
AS891_03135	COG0693	protein deglycase activity
AS891_03155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS891_03160	COG0500	methyltransferase
AS891_03170	COG2610	gluconate transmembrane transporter activity
AS891_03175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS891_03180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS891_03185	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_03190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS891_03195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS891_03200	COG4894	glucomannan catabolic process
AS891_03215	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS891_03220	COG2197	response regulator
AS891_03225	COG4585	Histidine kinase
AS891_03235	COG0583	DNA-binding transcription factor activity
AS891_03240	COG1881	PFAM PEBP family protein
AS891_03245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS891_03255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_03260	COG1012	belongs to the aldehyde dehydrogenase family
AS891_03265	COG2508	Transcriptional regulator
AS891_03270	COG3842	ATPase activity
AS891_03275	COG0726	polysaccharide deacetylase
AS891_03285	COG0501	Belongs to the peptidase M48B family
AS891_03290	COG3493	citrate carrier protein
AS891_03295	COG1271	oxidase subunit
AS891_03300	COG1294	oxidase, subunit
AS891_03305	COG4988	ABC transporter
AS891_03310	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AS891_03315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AS891_03320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS891_03325	COG1595	DNA-templated transcription, initiation
AS891_03345	COG1131	(ABC) transporter
AS891_03350	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS891_03355	COG2814	Major facilitator Superfamily
AS891_03360	COG0753	catalase activity
AS891_03365	COG2094	Belongs to the DNA glycosylase MPG family
AS891_03375	COG3711	transcriptional antiterminator
AS891_03375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_03380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_03385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_03390	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS891_03395	COG1486	melibiose metabolic process
AS891_03400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_03405	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AS891_03410	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS891_03415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_03420	COG1696	Membrane protein involved in D-alanine export
AS891_03425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_03440	COG1575	Belongs to the MenA family. Type 1 subfamily
AS891_03445	COG2357	RelA SpoT domain protein
AS891_03450	COG2234	aminopeptidase activity
AS891_03455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS891_03460	COG1846	Transcriptional regulator
AS891_03465	COG5522	Integral membrane protein (intg_mem_TP0381)
AS891_03470	COG1442	glycosyl transferase family 8
AS891_03475	COG3711	transcriptional antiterminator
AS891_03480	COG1263	PTS System
AS891_03480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_03485	COG1404	Belongs to the peptidase S8 family
AS891_03490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_03500	COG0346	lactoylglutathione lyase activity
AS891_03505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS891_03510	COG4895	conserved protein (DUF2196)
AS891_03515	COG2814	Major facilitator Superfamily
AS891_03520	COG1346	cytolysis
AS891_03525	COG1380	Effector of murein hydrolase LrgA
AS891_03530	COG0583	DNA-binding transcription factor activity
AS891_03535	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AS891_03540	COG0352	thiamine-phosphate diphosphorylase activity
AS891_03545	COG0672	)-iron permease
AS891_03550	COG2822	iron ion transport
AS891_03555	COG2837	iron assimilation
AS891_03560	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS891_03565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_03570	COG3162	membrane
AS891_03585	COG2246	polysaccharide biosynthetic process
AS891_03590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AS891_03595	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AS891_03600	COG2261	transglycosylase associated protein
AS891_03605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS891_03610	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS891_03615	COG1845	cytochrome c oxidase, subunit III
AS891_03620	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AS891_03630	COG0772	Belongs to the SEDS family
AS891_03635	COG0778	Nitroreductase
AS891_03640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_03645	COG1404	Belongs to the peptidase S8 family
AS891_03655	COG3711	transcriptional antiterminator
AS891_03660	COG2116	formate transmembrane transporter activity
AS891_03665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_03665	COG1263	PTS System
AS891_03670	COG1621	beta-fructofuranosidase activity
AS891_03680	COG0351	phosphomethylpyrimidine kinase
AS891_03685	COG1695	Transcriptional regulator
AS891_03700	COG1216	Glycosyl transferase, family 2
AS891_03705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AS891_03710	COG1012	belongs to the aldehyde dehydrogenase family
AS891_03720	COG2233	PERMEase
AS891_03725	COG2363	Small membrane protein
AS891_03740	COG0463	Glycosyl transferase, family 2
AS891_03745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_03750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS891_03755	COG0456	acetyltransferase
AS891_03760	COG2089	acid synthase
AS891_03765	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AS891_03770	COG3980	spore coat polysaccharide biosynthesis protein
AS891_03775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS891_03780	COG1088	dTDP-glucose 4,6-dehydratase activity
AS891_03785	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS891_03790	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AS891_03800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS891_03805	COG1012	belongs to the aldehyde dehydrogenase family
AS891_03810	COG4187	Peptidase family M20/M25/M40
AS891_03815	COG0833	amino acid
AS891_03820	COG2814	Major facilitator Superfamily
AS891_03825	COG0077	Prephenate dehydratase
AS891_03830	COG1917	Cupin 2, conserved barrel domain protein
AS891_03835	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_03840	COG0151	Belongs to the GarS family
AS891_03845	COG2814	Major facilitator Superfamily
AS891_03850	COG0436	Aminotransferase
AS891_03855	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_03865	COG0280	phosphate acetyltransferase
AS891_03870	COG0583	DNA-binding transcription factor activity
AS891_03875	COG0095	Lipoate-protein ligase
AS891_03880	COG0697	spore germination
AS891_03890	COG4844	belongs to the
AS891_03895	COG1078	dGTPase activity
AS891_03900	COG3465	dGTPase activity
AS891_03905	COG1959	2 iron, 2 sulfur cluster binding
AS891_03910	COG0477	Major facilitator Superfamily
AS891_03920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS891_03925	COG1846	Transcriptional regulator
AS891_03930	COG1942	4-Oxalocrotonate Tautomerase
AS891_03935	COG1994	Peptidase M50
AS891_03945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_03950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS891_03955	COG0010	Belongs to the arginase family
AS891_03960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS891_03970	COG0457	Tetratricopeptide repeat
AS891_03980	COG3391	amine dehydrogenase activity
AS891_03985	COG3391	amine dehydrogenase activity
AS891_03995	COG0612	Peptidase, M16
AS891_04000	COG0612	Peptidase, M16
AS891_04005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS891_04010	COG1131	(ABC) transporter
AS891_04020	COG0535	radical SAM domain protein
AS891_04030	COG4506	Protein conserved in bacteria
AS891_04035	COG0018	arginyl-trna synthetase
AS891_04040	COG2223	nitrite transmembrane transporter activity
AS891_04045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS891_04055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS891_04060	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AS891_04065	COG1140	nitrate reductase beta subunit
AS891_04070	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AS891_04075	COG2181	nitrate reductase activity
AS891_04080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS891_04085	COG1132	(ABC) transporter
AS891_04090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS891_04100	COG4294	response to UV
AS891_04105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS891_04110	COG2181	nitrate reductase activity
AS891_04110	COG0247	lactate metabolic process
AS891_04115	COG1960	acyl-CoA dehydrogenase activity
AS891_04120	COG3343	RNA polymerase activity
AS891_04125	COG0504	CTP synthase activity
AS891_04130	COG4821	SIS domain
AS891_04135	COG2204	response regulator
AS891_04140	COG0191	fructose-bisphosphate aldolase activity
AS891_04145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS891_04150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS891_04155	COG1494	fructose-1,6-bisphosphatase
AS891_04165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS891_04170	COG0254	rRNA binding
AS891_04175	COG1435	thymidine kinase activity
AS891_04180	COG0281	malic enzyme
AS891_04185	COG0679	Auxin Efflux Carrier
AS891_04190	COG0789	Transcriptional regulator
AS891_04195	COG0346	lactoylglutathione lyase activity
AS891_04200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS891_04205	COG2890	protein-(glutamine-N5) methyltransferase activity
AS891_04225	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AS891_04230	COG0009	L-threonylcarbamoyladenylate synthase
AS891_04235	COG1971	Probably functions as a manganese efflux pump
AS891_04240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS891_04245	COG0698	ribose 5-phosphate isomerase
AS891_04250	COG4475	Protein of unknown function (DUF436)
AS891_04255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AS891_04260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AS891_04270	COG0356	it plays a direct role in the translocation of protons across the membrane
AS891_04275	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS891_04285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AS891_04290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AS891_04295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AS891_04300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AS891_04305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AS891_04310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AS891_04320	COG4836	Membrane
AS891_04330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS891_04335	COG2385	sporulation resulting in formation of a cellular spore
AS891_04340	COG2304	oxidoreductase activity
AS891_04350	COG2304	oxidoreductase activity
AS891_04360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS891_04365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS891_04370	COG0457	Tetratricopeptide repeat
AS891_04375	COG1994	Peptidase M50
AS891_04380	COG3237	CsbD-like
AS891_04390	COG0831	urea catabolic process
AS891_04395	COG0832	Belongs to the urease beta subunit family
AS891_04400	COG0804	urea catabolic process
AS891_04405	COG1959	2 iron, 2 sulfur cluster binding
AS891_04410	COG2910	NAD(P)H-binding
AS891_04420	COG0789	Transcriptional regulator
AS891_04425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS891_04445	COG1247	-acetyltransferase
AS891_04450	COG0739	heme binding
AS891_04460	COG0671	phosphoesterase, PA-phosphatase related
AS891_04465	COG0347	Belongs to the P(II) protein family
AS891_04470	COG0004	ammonium transporteR
AS891_04480	COG1335	isochorismatase
AS891_04485	COG0477	Major facilitator Superfamily
AS891_04490	COG1953	Uracil, thiamine, allantoin
AS891_04495	COG3420	alginic acid biosynthetic process
AS891_04500	COG2814	Major facilitator Superfamily
AS891_04505	COG1846	Transcriptional regulator
AS891_04510	COG1609	Transcriptional regulator
AS891_04515	COG1077	Cell shape determining protein MreB Mrl
AS891_04520	COG4786	Flagellar basal body rod
AS891_04525	COG4786	Flagellar basal body rod
AS891_04530	COG0457	Tetratricopeptide repeat
AS891_04535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS891_04540	COG1970	mechanosensitive ion channel activity
AS891_04545	COG2972	Histidine kinase
AS891_04545	COG0745	RESPONSE REGULATOR receiver
AS891_04555	COG3764	Sortase (surface protein transpeptidase)
AS891_04570	COG0629	single-stranded DNA binding
AS891_04575	COG1349	DNA-binding transcription factor activity
AS891_04580	COG0561	phosphatase activity
AS891_04585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS891_04590	COG4715	Zinc finger, swim domain protein
AS891_04600	COG3944	biosynthesis protein
AS891_04605	COG0489	protein tyrosine kinase activity
AS891_04610	COG4464	protein tyrosine phosphatase activity
AS891_04615	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS891_04620	COG3878	Protein conserved in bacteria
AS891_04635	COG5444	nuclease activity
AS891_04640	COG2849	repeat protein
AS891_04645	COG1515	deoxyribonuclease V activity
AS891_04650	COG0583	DNA-binding transcription factor activity
AS891_04655	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS891_04665	COG2059	Chromate
AS891_04670	COG2059	Chromate
AS891_04675	COG1522	sequence-specific DNA binding
AS891_04680	COG0405	Gamma-glutamyltransferase
AS891_04690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS891_04700	COG5337	Spore coat protein CotH
AS891_04715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS891_04720	COG0583	DNA-binding transcription factor activity
AS891_04725	COG0028	Belongs to the TPP enzyme family
AS891_04730	COG3527	Alpha-acetolactate decarboxylase
AS891_04735	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS891_04745	COG3103	Sh3 type 3 domain protein
AS891_04750	COG1879	ABC-type sugar transport system periplasmic component
AS891_04755	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS891_04760	COG1129	ABC transporter
AS891_04765	COG1869	D-ribose catabolic process
AS891_04770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_04775	COG1609	Transcriptional regulator
AS891_04780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS891_04790	COG2843	Capsule synthesis protein
AS891_04800	COG0791	NLP P60 protein
AS891_04805	COG0561	phosphatase activity
AS891_04810	COG1316	TRANSCRIPTIONal
AS891_04815	COG2814	Major facilitator Superfamily
AS891_04825	COG0814	amino acid
AS891_04830	COG0697	spore germination
AS891_04840	COG1482	cell wall glycoprotein biosynthetic process
AS891_04845	COG4193	domain, Protein
AS891_04855	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_04860	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AS891_04865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AS891_04870	COG0438	transferase activity, transferring glycosyl groups
AS891_04875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_04880	COG1682	transport, permease protein
AS891_04885	COG1134	teichoic acid transport
AS891_04900	COG0463	Glycosyl transferase, family 2
AS891_04905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS891_04905	COG1215	transferase activity, transferring glycosyl groups
AS891_04910	COG1682	transport, permease protein
AS891_04915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS891_04920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS891_04925	COG1316	TRANSCRIPTIONal
AS891_04935	COG2385	sporulation resulting in formation of a cellular spore
AS891_04935	COG2247	cell wall binding repeat
AS891_04940	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_04940	COG2247	cell wall binding repeat
AS891_04950	COG2244	polysaccharide biosynthetic process
AS891_04955	COG0297	glycogen (starch) synthase activity
AS891_04955	COG0438	transferase activity, transferring glycosyl groups
AS891_04960	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS891_04965	COG3307	-O-antigen
AS891_04970	COG3206	protein involved in exopolysaccharide biosynthesis
AS891_04975	COG1215	transferase activity, transferring glycosyl groups
AS891_04980	COG0438	transferase activity, transferring glycosyl groups
AS891_04985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS891_04990	COG1316	TRANSCRIPTIONal
AS891_04995	COG1739	Uncharacterized protein family UPF0029
AS891_05000	COG4585	Histidine kinase
AS891_05005	COG2197	response regulator
AS891_05010	COG1307	EDD domain protein, DegV family
AS891_05015	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AS891_05025	COG1040	competence protein
AS891_05035	COG2747	anti-sigma28 factor FlgM
AS891_05040	COG3418	PFAM FlgN family protein
AS891_05045	COG4786	Flagellar basal body rod
AS891_05045	COG1256	bacterial-type flagellum assembly
AS891_05050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS891_05060	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AS891_05065	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AS891_05070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS891_05075	COG1334	flagellar protein FlaG
AS891_05080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AS891_05085	COG1516	flagellar protein fliS
AS891_05100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS891_05105	COG0653	protein targeting
AS891_05110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS891_05115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_05120	COG2010	Cytochrome c
AS891_05125	COG2884	Cell division ATP-binding protein ftsE
AS891_05130	COG2177	Part of the ABC transporter FtsEX involved in
AS891_05135	COG3409	Peptidoglycan-binding domain 1 protein
AS891_05135	COG0793	Belongs to the peptidase S41A family
AS891_05145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_05150	COG2814	Major facilitator Superfamily
AS891_05155	COG1309	transcriptional regulator
AS891_05160	COG3848	Pyruvate phosphate dikinase
AS891_05160	COG0574	Belongs to the PEP-utilizing enzyme family
AS891_05165	COG4897	Protein conserved in bacteria
AS891_05170	COG0556	nucleotide-excision repair
AS891_05175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS891_05180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS891_05195	COG3595	metallopeptidase activity
AS891_05200	COG1983	PspC domain protein
AS891_05205	COG1950	PFAM Membrane protein of
AS891_05210	COG2814	Major facilitator Superfamily
AS891_05215	COG1846	Transcriptional regulator
AS891_05225	COG2124	cytochrome p450
AS891_05230	COG1846	Transcriptional regulator
AS891_05235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS891_05245	COG0363	glucosamine-6-phosphate deaminase activity
AS891_05250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS891_05255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AS891_05260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AS891_05265	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS891_05270	COG0546	phosphoglycolate phosphatase activity
AS891_05275	COG0110	maltose O-acetyltransferase activity
AS891_05280	COG5297	Belongs to the glycosyl hydrolase family 6
AS891_05285	COG4990	cell redox homeostasis
AS891_05290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AS891_05295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AS891_05300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AS891_05305	COG0131	Imidazoleglycerol-phosphate dehydratase
AS891_05310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AS891_05315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AS891_05320	COG0107	imidazoleglycerol-phosphate synthase activity
AS891_05325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AS891_05325	COG0140	phosphoribosyl-ATP diphosphatase activity
AS891_05345	COG1132	(ABC) transporter
AS891_05350	COG0457	Tetratricopeptide repeat
AS891_05355	COG0791	NLP P60 protein
AS891_05355	COG3883	PFAM NLP P60 protein
AS891_05360	COG0492	ferredoxin-NADP+ reductase activity
AS891_05365	COG1051	belongs to the nudix hydrolase family
AS891_05370	COG1660	Displays ATPase and GTPase activities
AS891_05375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS891_05380	COG1481	regulation of sporulation
AS891_05385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_05390	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AS891_05400	COG0745	RESPONSE REGULATOR receiver
AS891_05405	COG5002	protein histidine kinase activity
AS891_05410	COG1136	(ABC) transporter
AS891_05415	COG0577	efflux transmembrane transporter activity
AS891_05420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS891_05425	COG0288	reversible hydration of carbon dioxide
AS891_05430	COG0659	secondary active sulfate transmembrane transporter activity
AS891_05435	COG1694	Mazg nucleotide pyrophosphohydrolase
AS891_05440	COG1611	Belongs to the LOG family
AS891_05445	COG1609	Transcriptional regulator
AS891_05450	COG0366	Alpha amylase catalytic
AS891_05455	COG2182	Extracellular solute-binding protein
AS891_05460	COG1175	transmembrane transport
AS891_05465	COG3833	ABC-type maltose transport systems, permease component
AS891_05470	COG5521	maltodextrose utilization protein MalA
AS891_05475	COG1554	hydrolase, family 65, central catalytic
AS891_05480	COG0366	Alpha amylase catalytic
AS891_05485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS891_05490	COG0740	serine-type endopeptidase activity
AS891_05500	COG3621	Patatin-like phospholipase
AS891_05505	COG0277	FAD linked oxidase domain protein
AS891_05515	COG2076	Multidrug Resistance protein
AS891_05520	COG2076	Multidrug Resistance protein
AS891_05525	COG1309	transcriptional regulator
AS891_05530	COG0531	amino acid
AS891_05535	COG1621	beta-fructofuranosidase activity
AS891_05540	COG1621	beta-fructofuranosidase activity
AS891_05545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS891_05550	COG1794	racemase activity, acting on amino acids and derivatives
AS891_05560	COG3479	Phenolic acid decarboxylase
AS891_05570	COG2272	Belongs to the type-B carboxylesterase lipase family
AS891_05575	COG1396	sequence-specific DNA binding
AS891_05580	COG3944	biosynthesis protein
AS891_05585	COG0489	protein tyrosine kinase activity
AS891_05590	COG1086	Polysaccharide biosynthesis protein
AS891_05595	COG0438	transferase activity, transferring glycosyl groups
AS891_05600	COG1215	transferase activity, transferring glycosyl groups
AS891_05605	COG0438	transferase activity, transferring glycosyl groups
AS891_05615	COG1216	Glycosyl transferase, family 2
AS891_05620	COG5039	Polysaccharide pyruvyl transferase
AS891_05625	COG1216	Glycosyl transferase, family 2
AS891_05630	COG2244	polysaccharide biosynthetic process
AS891_05635	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS891_05640	COG0110	maltose O-acetyltransferase activity
AS891_05645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS891_05650	COG5039	Polysaccharide pyruvyl transferase
AS891_05660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AS891_05665	COG1620	l-lactate permease
AS891_05670	COG2186	Transcriptional regulator
AS891_05675	COG1609	Transcriptional regulator
AS891_05680	COG2182	Extracellular solute-binding protein
AS891_05685	COG1175	transmembrane transport
AS891_05690	COG3833	ABC-type maltose transport systems, permease component
AS891_05695	COG1874	Beta-galactosidase
AS891_05700	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AS891_05705	COG2208	phosphoserine phosphatase activity
AS891_05710	COG0596	Alpha beta hydrolase
AS891_05715	COG1131	(ABC) transporter
AS891_05720	COG0842	Transport permease protein
AS891_05725	COG4585	Histidine kinase
AS891_05730	COG2197	response regulator
AS891_05735	COG0247	lactate metabolic process
AS891_05740	COG1139	Iron-sulfur cluster binding protein
AS891_05745	COG1556	Lactate utilization protein
AS891_05750	COG3858	chitin binding
AS891_05755	COG1113	amino acid transport
AS891_05760	COG0697	spore germination
AS891_05765	COG0583	DNA-binding transcription factor activity
AS891_05770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_05775	COG1609	Transcriptional regulator
AS891_05780	COG2814	Major facilitator Superfamily
AS891_05785	COG2390	Transcriptional regulator
AS891_05790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS891_05800	COG0126	phosphoglycerate kinase activity
AS891_05805	COG0149	triose-phosphate isomerase activity
AS891_05810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AS891_05815	COG0148	phosphopyruvate hydratase activity
AS891_05820	COG0456	acetyltransferase
AS891_05825	COG4640	response to antibiotic
AS891_05830	COG3064	Membrane
AS891_05840	COG2095	MarC family integral membrane protein
AS891_05845	COG1510	regulation of RNA biosynthetic process
AS891_05850	COG1125	glycine betaine transport
AS891_05850	COG0517	IMP dehydrogenase activity
AS891_05855	COG1174	glycine betaine transport
AS891_05860	COG1732	Glycine betaine
AS891_05865	COG1174	glycine betaine transport
AS891_05870	COG0640	Transcriptional regulator
AS891_05875	COG5658	integral membrane protein
AS891_05895	COG1510	regulation of RNA biosynthetic process
AS891_05900	COG1125	glycine betaine transport
AS891_05900	COG0517	IMP dehydrogenase activity
AS891_05905	COG1174	glycine betaine transport
AS891_05910	COG1732	Glycine betaine
AS891_05915	COG1174	glycine betaine transport
AS891_05920	COG0840	transmembrane signaling receptor activity
AS891_05925	COG1733	regulation of RNA biosynthetic process
AS891_05930	COG1396	sequence-specific DNA binding
AS891_05935	COG1396	sequence-specific DNA binding
AS891_05940	COG1476	TRANSCRIPTIONal
AS891_05945	COG0596	Alpha beta hydrolase
AS891_05950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS891_05955	COG1647	Serine aminopeptidase, S33
AS891_05960	COG0557	exoribonuclease II activity
AS891_05965	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AS891_05975	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_05980	COG1309	transcriptional regulator
AS891_05985	COG2076	Multidrug Resistance protein
AS891_05995	COG1289	transmembrane transporter activity
AS891_06000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS891_06005	COG0673	inositol 2-dehydrogenase activity
AS891_06010	COG1937	Protein conserved in bacteria
AS891_06015	COG2608	mercury ion transmembrane transporter activity
AS891_06020	COG2217	Heavy metal translocating P-type atpase
AS891_06025	COG2217	Heavy metal translocating P-type atpase
AS891_06030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AS891_06035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS891_06040	COG2860	membrane
AS891_06045	COG3973	AAA domain
AS891_06050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS891_06055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS891_06060	COG0025	NhaP-type Na H and K H
AS891_06070	COG0656	L-ascorbic acid biosynthetic process
AS891_06075	COG4149	molybdate abc transporter
AS891_06080	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS891_06085	COG1910	domain protein
AS891_06090	COG1368	sulfuric ester hydrolase activity
AS891_06095	COG1988	membrane-bound metal-dependent
AS891_06105	COG0531	amino acid
AS891_06115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_06120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_06125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_06130	COG1120	ATPase activity
AS891_06135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS891_06140	COG1136	(ABC) transporter
AS891_06145	COG0577	efflux transmembrane transporter activity
AS891_06155	COG2140	Oxalate decarboxylase
AS891_06165	COG1191	sigma factor activity
AS891_06175	COG0745	RESPONSE REGULATOR receiver
AS891_06180	COG2205	protein histidine kinase activity
AS891_06185	COG3386	PFAM SMP-30 Gluconolaconase
AS891_06190	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_06195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_06200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_06205	COG1120	ATPase activity
AS891_06210	COG2096	Adenosyltransferase
AS891_06215	COG2814	Major facilitator Superfamily
AS891_06220	COG4758	membrane
AS891_06225	COG1842	Phage shock protein A
AS891_06230	COG3595	metallopeptidase activity
AS891_06235	COG4758	membrane
AS891_06240	COG4585	Histidine kinase
AS891_06245	COG2197	response regulator
AS891_06255	COG0814	amino acid
AS891_06260	COG0697	spore germination
AS891_06270	COG0114	fumarate hydratase activity
AS891_06275	COG1309	transcriptional regulator
AS891_06285	COG2770	Histidine kinase
AS891_06285	COG2205	protein histidine kinase activity
AS891_06290	COG0745	RESPONSE REGULATOR receiver
AS891_06295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_06300	COG0783	Belongs to the Dps family
AS891_06305	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_06325	COG1120	ATPase activity
AS891_06335	COG0583	DNA-binding transcription factor activity
AS891_06340	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_06345	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_06350	COG1942	4-Oxalocrotonate Tautomerase
AS891_06355	COG0477	Major facilitator Superfamily
AS891_06360	COG1846	Transcriptional regulator
AS891_06365	COG5577	PFAM Coat F domain
AS891_06375	COG0506	proline dehydrogenase activity
AS891_06385	COG1024	Enoyl-CoA hydratase
AS891_06385	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS891_06390	COG0183	Belongs to the thiolase family
AS891_06395	COG1960	acyl-CoA dehydrogenase activity
AS891_06400	COG1393	Belongs to the ArsC family
AS891_06405	COG0509	glycine decarboxylation via glycine cleavage system
AS891_06415	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS891_06420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_06430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS891_06435	COG2011	ABC-type metal ion transport system permease component
AS891_06440	COG1464	Belongs to the NlpA lipoprotein family
AS891_06445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS891_06455	COG0396	ATPase activity
AS891_06460	COG0719	Fe-S assembly protein
AS891_06465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS891_06470	COG0822	iron-sulfur transferase activity
AS891_06475	COG0719	Fe-S assembly protein
AS891_06480	COG0640	Transcriptional regulator
AS891_06485	COG0346	lactoylglutathione lyase activity
AS891_06500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS891_06505	COG0322	excinuclease ABC activity
AS891_06510	COG2222	sugar isomerase
AS891_06515	COG1653	transport
AS891_06520	COG1175	transmembrane transport
AS891_06525	COG0395	ABC-type sugar transport system, permease component
AS891_06530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_06535	COG2188	Transcriptional regulator
AS891_06540	COG3842	ATPase activity
AS891_06545	COG2356	endonuclease I
AS891_06555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_06560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS891_06565	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AS891_06570	COG2068	MobA-Related Protein
AS891_06575	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AS891_06580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AS891_06585	COG2080	2 iron, 2 sulfur cluster binding
AS891_06595	COG2351	hydroxyisourate hydrolase activity
AS891_06600	COG3648	Uricase
AS891_06600	COG3195	allantoin biosynthetic process
AS891_06605	COG2233	PERMEase
AS891_06610	COG2233	PERMEase
AS891_06615	COG2508	Transcriptional regulator
AS891_06620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS891_06630	COG1801	Protein of unknown function DUF72
AS891_06635	COG0730	response to heat
AS891_06640	COG0737	Belongs to the 5'-nucleotidase family
AS891_06645	COG3377	Domain of unknown function (DUF1805)
AS891_06655	COG0739	heme binding
AS891_06660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AS891_06670	COG4470	Protein conserved in bacteria
AS891_06675	COG2445	Protein of unknown function DUF86
AS891_06680	COG0647	UMP catabolic process
AS891_06685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS891_06690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_06695	COG0460	homoserine dehydrogenase
AS891_06700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS891_06705	COG0083	homoserine kinase activity
AS891_06710	COG0823	Involved in the tonB-independent uptake of proteins
AS891_06710	COG4946	Tricorn protease homolog
AS891_06710	COG1506	peptidase
AS891_06715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS891_06720	COG4837	Protein of unknown function (DUF1462)
AS891_06725	COG1252	NADH dehydrogenase
AS891_06730	COG4844	belongs to the
AS891_06735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS891_06740	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AS891_06745	COG0316	Belongs to the HesB IscA family
AS891_06750	COG0456	acetyltransferase
AS891_06755	COG2808	Putative FMN-binding domain
AS891_06760	COG0516	GMP reductase activity
AS891_06770	COG0492	ferredoxin-NADP+ reductase activity
AS891_06775	COG1252	NADH dehydrogenase
AS891_06790	COG3584	3D domain protein
AS891_06795	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AS891_06800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS891_06805	COG2056	Na+-H+ antiporter family
AS891_06810	COG1268	BioY protein
AS891_06815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS891_06820	COG2819	hydrolase of the alpha beta superfamily
AS891_06825	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_06830	COG1169	isochorismate synthase
AS891_06835	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS891_06840	COG3433	isochorismatase activity
AS891_06840	COG1535	isochorismatase
AS891_06845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_06850	COG3251	PFAM MbtH domain protein
AS891_06855	COG5634	Uncharacterized conserved protein (DUF2278)
AS891_06860	COG0686	Belongs to the AlaDH PNT family
AS891_06865	COG2508	Transcriptional regulator
AS891_06865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AS891_06870	COG4842	Belongs to the WXG100 family
AS891_06875	COG5417	Belongs to the EsaB family
AS891_06880	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS891_06885	COG1674	ftsk spoiiie
AS891_06885	COG0433	COG0433 Predicted ATPase
AS891_06890	COG1511	domain protein
AS891_06900	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_06905	COG1418	mRNA catabolic process
AS891_06920	COG0628	permease
AS891_06935	COG5506	Protein of unknown function (DUF1694)
AS891_06940	COG1335	isochorismatase
AS891_06945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS891_06950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AS891_06965	COG0142	geranyltranstransferase activity
AS891_06975	COG4585	Histidine kinase
AS891_06980	COG2197	response regulator
AS891_06985	COG2050	protein possibly involved in aromatic compounds catabolism
AS891_06990	COG1320	monovalent cation:proton antiporter activity
AS891_06995	COG2212	antiporter activity
AS891_07000	COG1863	multisubunit Na H antiporter MnhE subunit
AS891_07005	COG0651	ATP synthesis coupled electron transport
AS891_07010	COG1006	Multisubunit Na H antiporter MnhC subunit
AS891_07015	COG2111	Na H antiporter
AS891_07020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS891_07020	COG2111	Na H antiporter
AS891_07030	COG3493	citrate carrier protein
AS891_07055	COG4565	transcriptional regulatory protein
AS891_07060	COG3290	protein histidine kinase activity
AS891_07070	COG3011	Protein conserved in bacteria
AS891_07075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_07080	COG2814	Major facilitator Superfamily
AS891_07090	COG5018	Exonuclease
AS891_07100	COG2205	protein histidine kinase activity
AS891_07105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AS891_07115	COG2267	carboxylic ester hydrolase activity
AS891_07120	COG1522	sequence-specific DNA binding
AS891_07125	COG0436	Aminotransferase
AS891_07130	COG1098	S1 RNA binding domain
AS891_07135	COG2155	Conserved Protein
AS891_07140	COG1979	alcohol dehydrogenase
AS891_07145	COG1979	alcohol dehydrogenase
AS891_07150	COG0166	Belongs to the GPI family
AS891_07165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS891_07180	COG2738	Putative neutral zinc metallopeptidase
AS891_07185	COG1253	flavin adenine dinucleotide binding
AS891_07190	COG0366	Alpha amylase catalytic
AS891_07195	COG0432	Pfam Uncharacterised protein family UPF0047
AS891_07210	COG0840	transmembrane signaling receptor activity
AS891_07215	COG0840	transmembrane signaling receptor activity
AS891_07220	COG0840	transmembrane signaling receptor activity
AS891_07225	COG0840	transmembrane signaling receptor activity
AS891_07230	COG3347	Dehydrogenase
AS891_07230	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_07235	COG1349	DNA-binding transcription factor activity
AS891_07240	COG1070	Carbohydrate kinase
AS891_07245	COG3254	rhamnose metabolic process
AS891_07250	COG4806	L-rhamnose isomerase
AS891_07255	COG0673	inositol 2-dehydrogenase activity
AS891_07260	COG0628	permease
AS891_07265	COG1968	undecaprenyl-diphosphatase activity
AS891_07275	COG5553	Cysteine dioxygenase type I
AS891_07280	COG0477	Major facilitator Superfamily
AS891_07285	COG1705	Flagellar rod assembly protein muramidase FlgJ
AS891_07290	COG4682	membrane
AS891_07295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS891_07300	COG0569	domain protein
AS891_07310	COG1510	regulation of RNA biosynthetic process
AS891_07320	COG1454	alcohol dehydrogenase
AS891_07330	COG2318	DinB family
AS891_07335	COG1585	Membrane protein implicated in regulation of membrane protease activity
AS891_07340	COG2268	Band 7 protein
AS891_07345	COG1247	-acetyltransferase
AS891_07350	COG3859	Proton-coupled thiamine transporter YuaJ
AS891_07480	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AS891_07485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS891_07490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS891_07495	COG0297	glycogen (starch) synthase activity
AS891_07500	COG0058	SHG alpha-glucan phosphorylase activity
AS891_07505	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AS891_07510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_07515	COG0438	transferase activity, transferring glycosyl groups
AS891_07520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_07530	COG0438	transferase activity, transferring glycosyl groups
AS891_07535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_07540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS891_07545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS891_07550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS891_07555	COG1169	isochorismate synthase
AS891_07560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AS891_07565	COG0596	Alpha beta hydrolase
AS891_07570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS891_07575	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_07580	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_07585	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS891_07590	COG1121	(ABC) transporter
AS891_07595	COG1321	iron dependent repressor
AS891_07595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS891_07600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS891_07610	COG1294	oxidase, subunit
AS891_07615	COG1271	oxidase subunit
AS891_07620	COG0254	rRNA binding
AS891_07625	COG0288	reversible hydration of carbon dioxide
AS891_07630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AS891_07635	COG1854	S-ribosylhomocysteine lyase activity
AS891_07650	COG0783	Belongs to the Dps family
AS891_07655	COG4824	toxin secretion phage lysis holin
AS891_07660	COG0494	nUDIX hydrolase
AS891_07665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS891_07670	COG1116	anion transmembrane transporter activity
AS891_07675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS891_07680	COG1506	peptidase
AS891_07690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AS891_07695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AS891_07700	COG0367	asparagine synthase
AS891_07705	COG1113	amino acid transport
AS891_07710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AS891_07715	COG2267	carboxylic ester hydrolase activity
AS891_07725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AS891_07730	COG1242	4 iron, 4 sulfur cluster binding
AS891_07745	COG1725	Transcriptional regulator
AS891_07750	COG1131	(ABC) transporter
AS891_07765	COG1136	(ABC) transporter
AS891_07770	COG0577	efflux transmembrane transporter activity
AS891_07775	COG0745	RESPONSE REGULATOR receiver
AS891_07780	COG2205	protein histidine kinase activity
AS891_07785	COG1136	(ABC) transporter
AS891_07790	COG0577	efflux transmembrane transporter activity
AS891_07795	COG2433	Pfam Transposase IS66
AS891_07800	COG2814	Major facilitator Superfamily
AS891_07805	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_07805	COG2202	Pas domain
AS891_07815	COG0495	leucyl-tRNA aminoacylation
AS891_07820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_07825	COG1486	melibiose metabolic process
AS891_07850	COG1073	alpha beta
AS891_07855	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AS891_07860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS891_07865	COG0156	8-amino-7-oxononanoate synthase activity
AS891_07870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS891_07875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AS891_07880	COG2124	cytochrome p450
AS891_07885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_07890	COG0395	ABC-type sugar transport system, permease component
AS891_07895	COG1653	transport
AS891_07900	COG2207	Transcriptional regulator
AS891_07905	COG4209	transmembrane transport
AS891_07910	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AS891_07915	COG1653	transport
AS891_07920	COG0673	inositol 2-dehydrogenase activity
AS891_07925	COG5578	integral membrane protein
AS891_07935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS891_07940	COG2081	HI0933 family
AS891_07945	COG2244	polysaccharide biosynthetic process
AS891_07950	COG1187	pseudouridine synthase activity
AS891_07955	COG1349	DNA-binding transcription factor activity
AS891_07960	COG1131	(ABC) transporter
AS891_07965	COG4473	ABC transporter
AS891_07970	COG2252	PERMEase
AS891_07975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_07980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS891_07985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AS891_07995	COG1597	lipid kinase activity
AS891_08000	COG1523	belongs to the glycosyl hydrolase 13 family
AS891_08005	COG0510	thiamine kinase activity
AS891_08015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AS891_08020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_08025	COG0281	malic enzyme
AS891_08030	COG5584	Small secreted protein
AS891_08035	COG1363	Peptidase, m42
AS891_08045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_08050	COG4848	Belongs to the UPF0354 family
AS891_08055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_08060	COG1674	ftsk spoiiie
AS891_08065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AS891_08070	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AS891_08075	COG4980	gas vesicle protein
AS891_08080	COG3118	belongs to the thioredoxin family
AS891_08085	COG1605	Chorismate mutase
AS891_08085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AS891_08090	COG1609	Transcriptional regulator
AS891_08095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS891_08100	COG1360	Flagellar Motor Protein
AS891_08105	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS891_08110	COG0517	IMP dehydrogenase activity
AS891_08115	COG0454	-acetyltransferase
AS891_08120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS891_08125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AS891_08135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AS891_08140	COG2199	diguanylate cyclase activity
AS891_08140	COG2203	Gaf domain
AS891_08145	COG1956	GAF domain-containing protein
AS891_08150	COG1309	transcriptional regulator
AS891_08155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS891_08160	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AS891_08165	COG1114	Component of the transport system for branched-chain amino acids
AS891_08170	COG1104	cysteine desulfurase activity
AS891_08175	COG0301	tRNA thio-modification
AS891_08185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS891_08190	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AS891_08195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS891_08200	COG0616	signal peptide processing
AS891_08205	COG1714	RDD family
AS891_08215	COG3874	Sporulation protein YtfJ
AS891_08220	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AS891_08225	COG0827	DNA restriction-modification system
AS891_08230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AS891_08235	COG0521	Mo-molybdopterin cofactor biosynthetic process
AS891_08240	COG0137	argininosuccinate synthase activity
AS891_08245	COG0165	Argininosuccinate lyase
AS891_08255	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_08260	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS891_08265	COG0583	DNA-binding transcription factor activity
AS891_08270	COG0454	-acetyltransferase
AS891_08275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_08280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_08285	COG0765	amino acid transport
AS891_08290	COG0765	amino acid transport
AS891_08295	COG1126	abc transporter atp-binding protein
AS891_08300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_08305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AS891_08310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_08315	COG0196	riboflavin kinase activity
AS891_08320	COG1473	amidohydrolase
AS891_08325	COG0730	response to heat
AS891_08335	COG4109	DRTGG domain
AS891_08345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS891_08365	COG0587	DNA-directed DNA polymerase activity
AS891_08370	COG0281	malic enzyme
AS891_08375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AS891_08380	COG0825	malonyl-CoA metabolic process
AS891_08385	COG0205	6-phosphofructokinase activity
AS891_08390	COG0469	pyruvate kinase activity
AS891_08395	COG3030	protein affecting phage T7 exclusion by the F plasmid
AS891_08400	COG0628	permease
AS891_08405	COG2707	UPF0756 membrane protein
AS891_08410	COG0372	Belongs to the citrate synthase family
AS891_08415	COG0538	isocitrate dehydrogenase activity
AS891_08420	COG0039	L-malate dehydrogenase activity
AS891_08425	COG0745	RESPONSE REGULATOR receiver
AS891_08430	COG5002	protein histidine kinase activity
AS891_08435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS891_08435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS891_08440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AS891_08455	COG0237	dephospho-CoA kinase activity
AS891_08460	COG0656	L-ascorbic acid biosynthetic process
AS891_08465	COG2814	Major facilitator Superfamily
AS891_08470	COG1733	regulation of RNA biosynthetic process
AS891_08475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS891_08480	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AS891_08485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AS891_08490	COG3611	Membrane attachment protein
AS891_08495	COG1484	DNA-dependent DNA replication
AS891_08500	COG0398	Pfam SNARE associated Golgi protein
AS891_08510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS891_08520	COG3275	phosphorelay sensor kinase activity
AS891_08525	COG3279	Response regulator of the LytR AlgR family
AS891_08530	COG1380	Effector of murein hydrolase LrgA
AS891_08535	COG1346	cytolysis
AS891_08545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AS891_08550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AS891_08555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AS891_08560	COG3326	Membrane
AS891_08570	COG1363	Peptidase, m42
AS891_08575	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_08580	COG2160	L-arabinose isomerase activity
AS891_08585	COG1069	ribulokinase activity
AS891_08590	COG0235	Class ii aldolase
AS891_08595	COG0647	UMP catabolic process
AS891_08600	COG0371	Dehydrogenase
AS891_08605	COG1653	transport
AS891_08610	COG1175	transmembrane transport
AS891_08615	COG0395	ABC-type sugar transport system, permease component
AS891_08620	COG3534	alpha-L-arabinofuranosidase
AS891_08625	COG1966	Carbon starvation protein
AS891_08635	COG0346	lactoylglutathione lyase activity
AS891_08640	COG0247	lactate metabolic process
AS891_08645	COG0277	FAD linked oxidase domain protein
AS891_08650	COG3835	regulator
AS891_08660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS891_08670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AS891_08675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_08675	COG0072	phenylalanine-tRNA ligase activity
AS891_08680	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AS891_08685	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AS891_08690	COG1286	toxin biosynthetic process
AS891_08695	COG1796	DNA polymerase
AS891_08695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS891_08700	COG1193	negative regulation of DNA recombination
AS891_08705	COG3766	membrane
AS891_08710	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_08715	COG1309	transcriptional regulator
AS891_08720	COG1024	Enoyl-CoA hydratase
AS891_08725	COG2086	electron transfer activity
AS891_08730	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS891_08735	COG3534	alpha-L-arabinofuranosidase
AS891_08740	COG3118	belongs to the thioredoxin family
AS891_08745	COG0322	excinuclease ABC activity
AS891_08750	COG0527	aspartate kinase activity
AS891_08755	COG1719	4-vinyl reductase, 4VR
AS891_08765	COG2009	succinate dehydrogenase
AS891_08770	COG1053	succinate dehydrogenase
AS891_08775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS891_08780	COG0824	Thioesterase
AS891_08785	COG2197	response regulator
AS891_08790	COG1846	Transcriptional regulator
AS891_08795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS891_08800	COG5401	PFAM Sporulation and spore germination
AS891_08805	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AS891_08810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AS891_08815	COG0622	Phosphoesterase
AS891_08825	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AS891_08835	COG0454	-acetyltransferase
AS891_08845	COG0028	Belongs to the TPP enzyme family
AS891_08850	COG0440	acetolactate synthase activity
AS891_08855	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AS891_08860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS891_08865	COG0473	3-isopropylmalate dehydrogenase activity
AS891_08870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AS891_08875	COG0066	3-isopropylmalate dehydratase activity
AS891_08880	COG1477	protein flavinylation
AS891_08880	COG0457	Tetratricopeptide repeat
AS891_08885	COG0544	peptidyl-prolyl cis-trans isomerase activity
AS891_08890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AS891_08895	COG1067	ATP-dependent peptidase activity
AS891_08895	COG0470	DNA polymerase III
AS891_08900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AS891_08905	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AS891_08915	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AS891_08920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS891_08925	COG0181	hydroxymethylbilane synthase activity
AS891_08930	COG1587	Uroporphyrinogen-III synthase
AS891_08935	COG0113	porphobilinogen synthase activity
AS891_08940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS891_08945	COG1388	LysM domain
AS891_08950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_08960	COG0525	valine-tRNA ligase activity
AS891_08965	COG0285	dihydrofolate synthase activity
AS891_08970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS891_08980	COG0424	maF-like protein
AS891_08985	COG2003	Belongs to the UPF0758 family
AS891_08990	COG1077	Cell shape determining protein MreB Mrl
AS891_08995	COG1792	Involved in formation and maintenance of cell shape
AS891_09000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AS891_09005	COG0850	regulation of cytokinetic process
AS891_09010	COG2894	cell division
AS891_09015	COG0739	heme binding
AS891_09020	COG1994	Peptidase M50
AS891_09025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AS891_09030	COG2868	ribosomal protein
AS891_09035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AS891_09045	COG3290	protein histidine kinase activity
AS891_09050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AS891_09055	COG4492	Belongs to the UPF0735 family
AS891_09060	COG0077	Prephenate dehydratase
AS891_09065	COG1827	regulation of RNA biosynthetic process
AS891_09070	COG1104	cysteine desulfurase activity
AS891_09075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS891_09080	COG0157	Belongs to the NadC ModD family
AS891_09085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AS891_09090	COG1388	LysM domain
AS891_09100	COG0217	transcriptional regulatory protein
AS891_09105	COG1115	amino acid carrier protein
AS891_09125	COG2112	serine threonine protein kinase
AS891_09130	COG0673	inositol 2-dehydrogenase activity
AS891_09135	COG2814	Major facilitator Superfamily
AS891_09145	COG0632	four-way junction helicase activity
AS891_09150	COG2255	four-way junction helicase activity
AS891_09160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AS891_09165	COG0343	queuine tRNA-ribosyltransferase activity
AS891_09170	COG1862	Preprotein translocase
AS891_09180	COG2323	membrane
AS891_09185	COG2244	polysaccharide biosynthetic process
AS891_09195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS891_09195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS891_09200	COG0490	domain, Protein
AS891_09205	COG5416	Lipopolysaccharide assembly protein A domain
AS891_09210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AS891_09210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS891_09215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS891_09220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS891_09225	COG1490	D-aminoacyl-tRNA deacylase activity
AS891_09230	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_09230	COG3103	Sh3 type 3 domain protein
AS891_09230	COG4991	sh3 domain protein
AS891_09240	COG0124	histidyl-tRNA synthetase
AS891_09245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AS891_09255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AS891_09260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS891_09265	COG1959	2 iron, 2 sulfur cluster binding
AS891_09270	COG1104	cysteine desulfurase activity
AS891_09275	COG0482	sulfurtransferase activity
AS891_09280	COG0457	Tetratricopeptide repeat
AS891_09285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS891_09290	COG3881	PFAM PRC-barrel domain
AS891_09305	COG0765	amino acid transport
AS891_09310	COG0765	amino acid transport
AS891_09315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_09320	COG1126	abc transporter atp-binding protein
AS891_09325	COG0628	permease
AS891_09330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS891_09335	COG4472	Bacterial protein of unknown function (DUF965)
AS891_09340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AS891_09345	COG3906	Belongs to the UPF0473 family
AS891_09350	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS891_09370	COG0572	uridine kinase
AS891_09375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AS891_09380	COG0768	penicillin binding
AS891_09395	COG2226	methyltransferase
AS891_09400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS891_09405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS891_09410	COG0626	cystathionine gamma-synthase activity
AS891_09420	COG2427	Protein of unknown function (DUF1641)
AS891_09425	COG3383	formate dehydrogenase (NAD+) activity
AS891_09430	COG5609	conserved protein (DUF2294)
AS891_09435	COG2116	formate transmembrane transporter activity
AS891_09445	COG2226	methyltransferase
AS891_09450	COG1309	transcriptional regulator
AS891_09455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS891_09455	COG2124	cytochrome p450
AS891_09465	COG2755	lipolytic protein G-D-S-L family
AS891_09465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AS891_09475	COG1595	DNA-templated transcription, initiation
AS891_09480	COG1378	Sugar-specific transcriptional regulator TrmB
AS891_09485	COG1280	lysine exporter protein (LysE YggA)
AS891_09490	COG1113	amino acid transport
AS891_09495	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AS891_09495	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AS891_09500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_09505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_09510	COG3715	PTS system
AS891_09515	COG3716	PTS system mannose fructose sorbose family IID component
AS891_09520	COG1621	beta-fructofuranosidase activity
AS891_09525	COG0693	protein deglycase activity
AS891_09530	COG1064	alcohol dehydrogenase
AS891_09540	COG0789	Transcriptional regulator
AS891_09545	COG5577	PFAM Coat F domain
AS891_09555	COG1063	alcohol dehydrogenase
AS891_09560	COG5577	PFAM Coat F domain
AS891_09570	COG0346	lactoylglutathione lyase activity
AS891_09575	COG4991	sh3 domain protein
AS891_09580	COG4991	sh3 domain protein
AS891_09585	COG0596	Alpha beta hydrolase
AS891_09590	COG5566	PFAM Mor transcription activator
AS891_09595	COG3409	Peptidoglycan-binding domain 1 protein
AS891_09600	COG2828	Protein conserved in bacteria
AS891_09605	COG0583	DNA-binding transcription factor activity
AS891_09610	COG2851	Citrate transporter
AS891_09615	COG0667	Aldo Keto reductase
AS891_09620	COG1595	DNA-templated transcription, initiation
AS891_09625	COG3443	Belongs to the bacterial solute-binding protein 9 family
AS891_09640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AS891_09650	COG2070	2-Nitropropane dioxygenase
AS891_09660	COG2318	DinB family
AS891_09670	COG1335	isochorismatase
AS891_09680	COG2124	cytochrome p450
AS891_09685	COG2732	(Barnase) inhibitor
AS891_09690	COG1522	sequence-specific DNA binding
AS891_09695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AS891_09700	COG1687	branched-chain amino acid
AS891_09705	COG1114	Component of the transport system for branched-chain amino acids
AS891_09715	COG0583	DNA-binding transcription factor activity
AS891_09720	COG1942	4-Oxalocrotonate Tautomerase
AS891_09725	COG1230	cation diffusion facilitator family transporter
AS891_09730	COG2072	flavoprotein involved in K transport
AS891_09735	COG0583	DNA-binding transcription factor activity
AS891_09740	COG0697	spore germination
AS891_09750	COG1253	flavin adenine dinucleotide binding
AS891_09755	COG0456	acetyltransferase
AS891_09760	COG2814	Major facilitator Superfamily
AS891_09765	COG4978	Transcriptional regulator
AS891_09765	COG0789	Transcriptional regulator
AS891_09780	COG0662	Cupin 2, conserved barrel domain protein
AS891_09785	COG1937	Protein conserved in bacteria
AS891_09790	COG2210	Belongs to the sulfur carrier protein TusA family
AS891_09795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_09795	COG0425	Belongs to the sulfur carrier protein TusA family
AS891_09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_09805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_09810	COG0425	Belongs to the sulfur carrier protein TusA family
AS891_09815	COG0730	response to heat
AS891_09825	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS891_09830	COG0454	-acetyltransferase
AS891_09840	COG2311	Membrane
AS891_09845	COG0745	RESPONSE REGULATOR receiver
AS891_09850	COG0642	Histidine kinase
AS891_09850	COG5002	protein histidine kinase activity
AS891_09855	COG3223	Belongs to the PsiE family
AS891_09870	COG2856	Zn peptidase
AS891_09875	COG0563	adenylate kinase activity
AS891_09885	COG3620	sequence-specific DNA binding
AS891_09890	COG1476	TRANSCRIPTIONal
AS891_09915	COG5377	YqaJ viral recombinase family
AS891_09920	COG3723	Recombinational DNA repair protein, rece pathway
AS891_09925	COG3935	DnaD domain protein
AS891_09930	COG1484	DNA-dependent DNA replication
AS891_09945	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AS891_09960	COG3677	Transposase
AS891_09970	COG5484	DNA packaging
AS891_09975	COG1783	phage Terminase large subunit
AS891_09980	COG5518	Phage portal protein
AS891_09985	COG2369	cell adhesion
AS891_09995	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AS891_10000	COG4653	Phage capsid family
AS891_10060	COG5280	Phage tail tape measure protein TP901
AS891_10060	COG3953	SLT domain
AS891_10065	COG1652	LysM domain
AS891_10070	COG4193	domain, Protein
AS891_10080	COG3628	GPW Gp25 family protein
AS891_10085	COG3299	homolog of phage Mu protein gp47
AS891_10090	COG3778	Protein conserved in bacteria
AS891_10120	COG4824	toxin secretion phage lysis holin
AS891_10125	COG3409	Peptidoglycan-binding domain 1 protein
AS891_10125	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_10150	COG5444	nuclease activity
AS891_10165	COG0457	Tetratricopeptide repeat
AS891_10170	COG3403	YqcI/YcgG family
AS891_10175	COG0640	Transcriptional regulator
AS891_10180	COG0346	lactoylglutathione lyase activity
AS891_10185	COG0798	PFAM Bile acid sodium symporter
AS891_10190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS891_10195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_10205	COG3209	COG3209 Rhs family protein
AS891_10215	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS891_10220	COG0398	Pfam SNARE associated Golgi protein
AS891_10225	COG3409	Peptidoglycan-binding domain 1 protein
AS891_10225	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_10230	COG2755	lipolytic protein G-D-S-L family
AS891_10245	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AS891_10250	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS891_10255	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AS891_10260	COG1534	Rna-binding protein
AS891_10265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AS891_10270	COG1713	HD superfamily hydrolase involved in NAD metabolism
AS891_10275	COG0799	negative regulation of ribosome biogenesis
AS891_10280	COG2226	methyltransferase
AS891_10285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_10290	COG1596	polysaccharide export
AS891_10290	COG1555	photosystem II stabilization
AS891_10295	COG2131	deaminase
AS891_10300	COG0658	competence protein
AS891_10300	COG2333	competence protein COMEC
AS891_10310	COG1466	dna polymerase III delta subunit
AS891_10315	COG0268	Binds directly to 16S ribosomal RNA
AS891_10320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AS891_10325	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_10335	COG0481	GTPase activity
AS891_10340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS891_10345	COG1420	regulation of RNA biosynthetic process
AS891_10350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AS891_10355	COG0443	Heat shock 70 kDa protein
AS891_10360	COG0484	heat shock protein binding
AS891_10365	COG2264	protein methyltransferase activity
AS891_10370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS891_10375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS891_10380	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS891_10385	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AS891_10390	COG1610	YqeY-like protein
AS891_10395	COG1030	water channel activity
AS891_10400	COG4864	UPF0365 protein
AS891_10415	COG0561	phosphatase activity
AS891_10420	COG1702	phosphate starvation-inducible protein PhoH
AS891_10430	COG1480	7TM receptor with intracellular HD hydrolase
AS891_10435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AS891_10440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AS891_10445	COG0295	cytidine deaminase activity
AS891_10450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS891_10460	COG1381	Involved in DNA repair and RecF pathway recombination
AS891_10465	COG0752	glycyl-tRNA synthetase alpha subunit
AS891_10470	COG0751	glycine-tRNA ligase activity
AS891_10475	COG0517	IMP dehydrogenase activity
AS891_10480	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AS891_10485	COG1671	Belongs to the UPF0178 family
AS891_10490	COG0358	DNA primase activity
AS891_10495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS891_10500	COG2010	Cytochrome c
AS891_10505	COG2384	SAM-dependent methyltransferase
AS891_10510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS891_10515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AS891_10525	COG0513	Belongs to the DEAD box helicase family
AS891_10530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AS891_10540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_10545	COG0735	belongs to the Fur family
AS891_10550	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AS891_10555	COG4709	membrane
AS891_10560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AS891_10565	COG1388	LysM domain
AS891_10575	COG5521	maltodextrose utilization protein MalA
AS891_10580	COG2839	Protein conserved in bacteria
AS891_10585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS891_10590	COG0477	Major facilitator Superfamily
AS891_10600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS891_10605	COG0573	inorganic phosphate transmembrane transporter activity
AS891_10610	COG0581	inorganic phosphate transmembrane transporter activity
AS891_10615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS891_10620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS891_10625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS891_10640	COG0438	transferase activity, transferring glycosyl groups
AS891_10645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AS891_10650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS891_10660	COG0705	Rhomboid family
AS891_10660	COG0457	Tetratricopeptide repeat
AS891_10665	COG4483	Protein conserved in bacteria
AS891_10670	COG1940	carbohydrate kinase activity
AS891_10675	COG1368	sulfuric ester hydrolase activity
AS891_10680	COG2866	Carboxypeptidase
AS891_10690	COG0011	TIGRFAM Protein of
AS891_10700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_10710	COG1393	Belongs to the ArsC family
AS891_10720	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_10725	COG1253	flavin adenine dinucleotide binding
AS891_10730	COG0598	Magnesium transport protein CorA
AS891_10740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS891_10745	COG1459	type II secretion system
AS891_10750	COG4537	Required for transformation and DNA binding
AS891_10755	COG4970	Tfp pilus assembly protein FimT
AS891_10765	COG4940	Competence protein ComGF
AS891_10790	COG0681	Belongs to the peptidase S26 family
AS891_10800	COG1396	sequence-specific DNA binding
AS891_10815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS891_10820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AS891_10825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS891_10830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AS891_10835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS891_10840	COG0095	Lipoate-protein ligase
AS891_10845	COG1321	iron dependent repressor
AS891_10850	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS891_10860	COG3872	metal-dependent enzyme
AS891_10870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AS891_10875	COG0006	proline dipeptidase activity
AS891_10880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AS891_10890	COG3854	ATPases associated with a variety of cellular activities
AS891_10930	COG0511	ligase activity, forming carbon-carbon bonds
AS891_10935	COG0439	Biotin carboxylase
AS891_10940	COG1302	Protein conserved in bacteria
AS891_10945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS891_10950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AS891_10955	COG1570	exodeoxyribonuclease VII activity
AS891_10960	COG1722	exodeoxyribonuclease VII activity
AS891_10965	COG0142	geranyltranstransferase activity
AS891_10970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AS891_10975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AS891_10980	COG1438	arginine binding
AS891_10985	COG0497	DNA recombination
AS891_10990	COG0750	zinc metalloprotease
AS891_11000	COG0745	RESPONSE REGULATOR receiver
AS891_11010	COG1902	pentaerythritol trinitrate reductase activity
AS891_11025	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_11030	COG0584	glycerophosphoryl diester phosphodiesterase
AS891_11035	COG0183	Belongs to the thiolase family
AS891_11040	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS891_11045	COG1960	acyl-CoA dehydrogenase activity
AS891_11050	COG0372	Belongs to the citrate synthase family
AS891_11055	COG2079	MmgE PrpD family protein
AS891_11060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AS891_11070	COG3829	transcription factor binding
AS891_11070	COG3290	protein histidine kinase activity
AS891_11075	COG0280	phosphate acetyltransferase
AS891_11080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS891_11085	COG3426	butyrate kinase activity
AS891_11090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS891_11095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS891_11100	COG0022	dehydrogenase e1 component
AS891_11105	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_11110	COG4978	Transcriptional regulator
AS891_11110	COG0789	Transcriptional regulator
AS891_11115	COG2814	Major facilitator Superfamily
AS891_11120	COG1597	lipid kinase activity
AS891_11130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_11135	COG0765	amino acid transport
AS891_11140	COG1126	abc transporter atp-binding protein
AS891_11145	COG4129	membrane
AS891_11150	COG1376	ErfK ybiS ycfS ynhG family protein
AS891_11160	COG0346	lactoylglutathione lyase activity
AS891_11165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS891_11170	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS891_11175	COG3361	conserved protein (COG2071)
AS891_11180	COG0706	membrane insertase activity
AS891_11190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_11195	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AS891_11200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS891_11205	COG1234	tRNA 3'-trailer cleavage
AS891_11210	COG0596	Alpha beta hydrolase
AS891_11215	COG1902	pentaerythritol trinitrate reductase activity
AS891_11220	COG4187	Peptidase family M20/M25/M40
AS891_11225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_11230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_11235	COG0300	oxidoreductase activity
AS891_11240	COG3048	D-serine ammonia-lyase activity
AS891_11245	COG1072	(Pantothenic acid kinase))
AS891_11250	COG0346	lactoylglutathione lyase activity
AS891_11260	COG2211	Major facilitator Superfamily
AS891_11270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_11280	COG0456	acetyltransferase
AS891_11285	COG2329	Antibiotic biosynthesis monooxygenase
AS891_11290	COG0456	acetyltransferase
AS891_11290	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS891_11295	COG4918	Iron-sulphur cluster biosynthesis
AS891_11305	COG1073	alpha beta
AS891_11315	COG0667	Aldo Keto reductase
AS891_11325	COG0494	nUDIX hydrolase
AS891_11330	COG1379	DNA repair
AS891_11335	COG1396	sequence-specific DNA binding
AS891_11340	COG0252	asparaginase activity
AS891_11345	COG1027	Aspartate ammonia-lyase
AS891_11350	COG1757	Na H antiporter
AS891_11355	COG0281	malic enzyme
AS891_11365	COG1300	Membrane
AS891_11370	COG0735	belongs to the Fur family
AS891_11380	COG4974	Belongs to the 'phage' integrase family
AS891_11385	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AS891_11390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AS891_11395	COG1686	Belongs to the peptidase S11 family
AS891_11400	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_11405	COG2172	sigma factor antagonist activity
AS891_11410	COG1191	sigma factor activity
AS891_11430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS891_11445	COG0697	spore germination
AS891_11450	COG0019	diaminopimelate decarboxylase activity
AS891_11455	COG4086	secreted protein
AS891_11460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS891_11485	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AS891_11490	COG0681	Belongs to the peptidase S26 family
AS891_11500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS891_11500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS891_11505	COG0307	riboflavin synthase, alpha
AS891_11510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS891_11510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AS891_11515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AS891_11520	COG0456	acetyltransferase
AS891_11525	COG1547	Domain of unknown function (DUF309)
AS891_11530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AS891_11535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AS891_11545	COG1686	Belongs to the peptidase S11 family
AS891_11550	COG2715	membrane protein required for spore maturation
AS891_11555	COG0700	Nucleoside recognition
AS891_11560	COG1187	pseudouridine synthase activity
AS891_11565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_11570	COG1333	cytochrome c biogenesis protein
AS891_11575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS891_11580	COG0745	RESPONSE REGULATOR receiver
AS891_11585	COG5002	protein histidine kinase activity
AS891_11590	COG1595	DNA-templated transcription, initiation
AS891_11600	COG0710	3-dehydroquinate dehydratase activity
AS891_11605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS891_11610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AS891_11615	COG1141	Ferredoxin
AS891_11620	COG4955	Helix-turn-helix domain
AS891_11625	COG0514	ATP-dependent DNA helicase (RecQ)
AS891_11630	COG1266	CAAX protease self-immunity
AS891_11635	COG1388	LysM domain
AS891_11645	COG1408	metallophosphoesterase
AS891_11650	COG4862	establishment of competence for transformation
AS891_11655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS891_11660	COG0492	ferredoxin-NADP+ reductase activity
AS891_11665	COG2339	peptidase activity
AS891_11670	COG3773	Cell wall hydrolase
AS891_11670	COG3409	Peptidoglycan-binding domain 1 protein
AS891_11675	COG2959	enzyme of heme biosynthesis
AS891_11680	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AS891_11690	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AS891_11695	COG0539	negative regulation of cytoplasmic translation
AS891_11700	COG1304	FMN binding
AS891_11725	COG1160	GTP binding
AS891_11730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AS891_11745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS891_11750	COG0776	regulation of translation
AS891_11755	COG0302	gtp cyclohydrolase
AS891_11765	COG0142	geranyltranstransferase activity
AS891_11770	COG2226	methyltransferase
AS891_11775	COG0142	geranyltranstransferase activity
AS891_11780	COG0105	UTP biosynthetic process
AS891_11790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS891_11795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AS891_11800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AS891_11805	COG4401	Chorismate mutase type I
AS891_11810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS891_11815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS891_11825	COG0135	phosphoribosylanthranilate isomerase activity
AS891_11830	COG0133	tryptophan synthase activity
AS891_11835	COG0159	tryptophan synthase activity
AS891_11840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS891_11845	COG0287	Prephenate dehydrogenase
AS891_11850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AS891_11855	COG0457	Tetratricopeptide repeat
AS891_11860	COG5582	Belongs to the UPF0302 family
AS891_11870	COG0723	plastoquinol--plastocyanin reductase activity
AS891_11875	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS891_11880	COG2010	Cytochrome c
AS891_11880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS891_11885	COG4347	Protein of unknown function (DUF1405)
AS891_11895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_11900	COG1694	Mazg nucleotide pyrophosphohydrolase
AS891_11905	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AS891_11910	COG1803	Methylglyoxal synthase
AS891_11915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS891_11920	COG0438	transferase activity, transferring glycosyl groups
AS891_11925	COG0617	tRNA 3'-terminal CCA addition
AS891_11930	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AS891_11930	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AS891_11935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AS891_11940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AS891_11945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AS891_11950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS891_11950	COG1199	ATP-dependent helicase activity
AS891_11960	COG5353	protein conserved in bacteria
AS891_11965	COG0436	Aminotransferase
AS891_11970	COG0017	Asparaginyl-tRNA synthetase
AS891_11975	COG3935	DnaD domain protein
AS891_11980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS891_11990	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS891_11990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_11995	COG3331	DNA recombination
AS891_12030	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_12035	COG2190	(PTS) system
AS891_12040	COG1205	dead DEAH box helicase
AS891_12040	COG1111	helicase
AS891_12045	COG3359	exonuclease
AS891_12055	COG4474	Belongs to the UPF0398 family
AS891_12070	COG0116	Belongs to the methyltransferase superfamily
AS891_12080	COG1199	ATP-dependent helicase activity
AS891_12085	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_12090	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AS891_12095	COG1609	Transcriptional regulator
AS891_12100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_12105	COG0800	Aldolase
AS891_12115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AS891_12120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS891_12125	COG2233	PERMEase
AS891_12130	COG3424	synthase
AS891_12135	COG1755	Isoprenylcysteine carboxyl methyltransferase
AS891_12140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS891_12160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS891_12170	COG0328	RNA-DNA hybrid ribonuclease activity
AS891_12175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AS891_12180	COG0328	RNA-DNA hybrid ribonuclease activity
AS891_12200	COG1278	Cold shock
AS891_12205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS891_12210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AS891_12215	COG0386	Belongs to the glutathione peroxidase family
AS891_12220	COG1418	mRNA catabolic process
AS891_12225	COG1413	lyase activity
AS891_12230	COG0129	dihydroxy-acid dehydratase activity
AS891_12240	COG2136	Putative SAM-dependent methyltransferase
AS891_12240	COG2521	methyltransferase
AS891_12250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS891_12255	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS891_12260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS891_12265	COG0204	Acyl-transferase
AS891_12270	COG1272	protein, Hemolysin III
AS891_12275	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AS891_12280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS891_12295	COG1999	signal sequence binding
AS891_12300	COG2755	lipolytic protein G-D-S-L family
AS891_12305	COG4698	Protein conserved in bacteria
AS891_12315	COG0534	Mate efflux family protein
AS891_12320	COG1846	Transcriptional regulator
AS891_12325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS891_12330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS891_12335	COG1086	Polysaccharide biosynthesis protein
AS891_12340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_12365	COG2746	aminoglycoside 3-N-acetyltransferase activity
AS891_12375	COG1525	nuclease
AS891_12385	COG4282	regulation of fungal-type cell wall biogenesis
AS891_12390	COG5444	nuclease activity
AS891_12405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_12435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_12450	COG3271	cysteine-type peptidase activity
AS891_12450	COG2274	protein secretion by the type I secretion system
AS891_12455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_12460	COG0463	Glycosyl transferase, family 2
AS891_12465	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS891_12480	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_12495	COG4632	Exopolysaccharide biosynthesis protein
AS891_12495	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_12505	COG2433	Pfam Transposase IS66
AS891_12515	COG0741	lytic transglycosylase activity
AS891_12515	COG0739	heme binding
AS891_12515	COG1196	nuclear chromosome segregation
AS891_12545	COG0582	viral genome integration into host DNA
AS891_12645	COG4373	Mu-like prophage FluMu protein gp28
AS891_12675	COG0776	regulation of translation
AS891_12690	COG1395	domain, Protein
AS891_12725	COG3655	Transcriptional regulator
AS891_12805	COG0582	viral genome integration into host DNA
AS891_12820	COG3655	Transcriptional regulator
AS891_12875	COG3645	SOS response
AS891_12875	COG3646	Phage regulatory protein
AS891_12895	COG1388	LysM domain
AS891_12905	COG4474	Belongs to the UPF0398 family
AS891_12960	COG1793	dna ligase
AS891_12965	COG2135	peptidase activity
AS891_12980	COG4195	phage-related replication protein
AS891_12985	COG3420	alginic acid biosynthetic process
AS891_12985	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_13015	COG2887	Belongs to the helicase family. UvrD subfamily
AS891_13025	COG0305	Participates in initiation and elongation during chromosome replication
AS891_13030	COG0358	DNA primase activity
AS891_13035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS891_13040	COG0587	DNA-directed DNA polymerase activity
AS891_13045	COG3584	3D domain protein
AS891_13070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS891_13075	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AS891_13085	COG0270	DNA (cytosine-5-)-methyltransferase activity
AS891_13175	COG1780	Probably involved in ribonucleotide reductase function
AS891_13180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_13180	COG1372	Participates in initiation and elongation during chromosome replication
AS891_13210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_13215	COG0756	dUTP diphosphatase activity
AS891_13220	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AS891_13255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS891_13305	COG3331	DNA recombination
AS891_13315	COG1086	Polysaccharide biosynthesis protein
AS891_13320	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AS891_13325	COG4641	Protein conserved in bacteria
AS891_13340	COG0463	Glycosyl transferase, family 2
AS891_13345	COG0456	acetyltransferase
AS891_13360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS891_13365	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS891_13370	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS891_13375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_13380	COG0456	acetyltransferase
AS891_13385	COG1509	lysine 2,3-aminomutase activity
AS891_13395	COG4479	Belongs to the UPF0346 family
AS891_13420	COG0671	phosphoesterase, PA-phosphatase related
AS891_13435	COG0813	purine-nucleoside phosphorylase activity
AS891_13440	COG1876	peptidase activity
AS891_13450	COG2226	methyltransferase
AS891_13455	COG0793	Belongs to the peptidase S41A family
AS891_13455	COG3409	Peptidoglycan-binding domain 1 protein
AS891_13460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_13470	COG0346	lactoylglutathione lyase activity
AS891_13475	COG0400	carboxylic ester hydrolase activity
AS891_13480	COG0778	Nitroreductase
AS891_13485	COG1733	regulation of RNA biosynthetic process
AS891_13490	COG1942	4-Oxalocrotonate Tautomerase
AS891_13495	COG2610	gluconate transmembrane transporter activity
AS891_13510	COG2962	Rard protein
AS891_13520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS891_13525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS891_13530	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_13535	COG0534	Mate efflux family protein
AS891_13540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS891_13545	COG1819	glycosyl
AS891_13550	COG1388	LysM domain
AS891_13550	COG0791	NLP P60 protein
AS891_13555	COG2032	superoxide dismutase activity
AS891_13560	COG0714	Associated with various cellular activities
AS891_13565	COG4548	von Willebrand factor, type A
AS891_13570	COG0567	Dehydrogenase, E1 component
AS891_13575	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_13580	COG0385	Bile acid
AS891_13585	COG0733	neurotransmitter:sodium symporter activity
AS891_13590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS891_13595	COG1657	PFAM Prenyltransferase squalene oxidase
AS891_13600	COG1012	belongs to the aldehyde dehydrogenase family
AS891_13625	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_13640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS891_13645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AS891_13660	COG0514	ATP-dependent DNA helicase (RecQ)
AS891_13665	COG3584	3D domain protein
AS891_13665	COG1388	LysM domain
AS891_13670	COG2197	response regulator
AS891_13675	COG4585	Histidine kinase
AS891_13680	COG3239	Fatty acid desaturase
AS891_13685	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS891_13700	COG2322	membrane
AS891_13705	COG0741	lytic transglycosylase activity
AS891_13710	COG0640	Transcriptional regulator
AS891_13720	COG2378	regulation of single-species biofilm formation
AS891_13725	COG3708	Transcriptional regulator
AS891_13730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_13735	COG1309	transcriptional regulator
AS891_13740	COG0456	acetyltransferase
AS891_13745	COG0662	Cupin 2, conserved barrel domain protein
AS891_13745	COG2207	Transcriptional regulator
AS891_13750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS891_13755	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_13760	COG1231	oxidoreductase activity
AS891_13765	COG4282	regulation of fungal-type cell wall biogenesis
AS891_13770	COG5444	nuclease activity
AS891_13790	COG5290	Psort location Cytoplasmic, score
AS891_13805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_13810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS891_13820	COG0457	Tetratricopeptide repeat
AS891_13850	COG1793	dna ligase
AS891_13855	COG2135	peptidase activity
AS891_13870	COG1396	sequence-specific DNA binding
AS891_13875	COG2314	TM2 domain
AS891_13880	COG0726	polysaccharide deacetylase
AS891_13885	COG3848	Pyruvate phosphate dikinase
AS891_13885	COG0574	Belongs to the PEP-utilizing enzyme family
AS891_13905	COG2367	Beta-lactamase
AS891_13910	COG0693	protein deglycase activity
AS891_13920	COG0697	spore germination
AS891_13925	COG0583	DNA-binding transcription factor activity
AS891_13930	COG3739	integral membrane protein
AS891_13935	COG3655	Transcriptional regulator
AS891_13945	COG2720	vancomycin resistance protein
AS891_13960	COG0456	acetyltransferase
AS891_13970	COG2140	Oxalate decarboxylase
AS891_13980	COG2135	peptidase activity
AS891_13985	COG3866	Pectate lyase
AS891_13990	COG3619	membrane
AS891_13995	COG4305	rare lipoprotein A
AS891_14000	COG2368	4-hydroxyphenylacetate
AS891_14005	COG5278	phosphoserine phosphatase activity
AS891_14005	COG0840	transmembrane signaling receptor activity
AS891_14030	COG0243	molybdopterin cofactor binding
AS891_14035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS891_14040	COG1070	Carbohydrate kinase
AS891_14045	COG2814	Major facilitator Superfamily
AS891_14050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_14060	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AS891_14065	COG0300	oxidoreductase activity
AS891_14075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_14080	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS891_14085	COG0583	DNA-binding transcription factor activity
AS891_14090	COG0067	glutamate synthase
AS891_14090	COG0070	glutamate synthase
AS891_14090	COG0069	glutamate synthase activity
AS891_14095	COG0493	'glutamate synthase
AS891_14100	COG0604	alcohol dehydrogenase
AS891_14105	COG0583	DNA-binding transcription factor activity
AS891_14110	COG0405	Gamma-glutamyltransferase
AS891_14115	COG0166	Belongs to the GPI family
AS891_14120	COG0582	viral genome integration into host DNA
AS891_14135	COG0534	Mate efflux family protein
AS891_14140	COG2017	converts alpha-aldose to the beta-anomer
AS891_14145	COG2027	D-alanyl-D-alanine carboxypeptidase
AS891_14150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AS891_14185	COG1649	PFAM Uncharacterised BCR, COG1649
AS891_14200	COG1960	acyl-CoA dehydrogenase activity
AS891_14205	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_14210	COG0439	Biotin carboxylase
AS891_14215	COG0511	ligase activity, forming carbon-carbon bonds
AS891_14220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS891_14225	COG1024	Enoyl-CoA hydratase
AS891_14230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS891_14235	COG2404	hydrolase activity, acting on ester bonds
AS891_14240	COG0586	Pfam SNARE associated Golgi protein
AS891_14245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS891_14250	COG2246	polysaccharide biosynthetic process
AS891_14255	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_14260	COG5520	Belongs to the glycosyl hydrolase 30 family
AS891_14270	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AS891_14275	COG1115	amino acid carrier protein
AS891_14290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS891_14295	COG0187	DNA topoisomerase II activity
AS891_14300	COG1832	CoA-binding protein
AS891_14305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AS891_14310	COG4841	protein insertion into membrane
AS891_14320	COG0824	Thioesterase
AS891_14340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_14345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS891_14360	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_14370	COG4846	Membrane protein involved in cytochrome C biogenesis
AS891_14375	COG2201	protein-glutamate methylesterase activity
AS891_14380	COG0785	Cytochrome C biogenesis protein
AS891_14390	COG3763	UPF0154 protein
AS891_14400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AS891_14405	COG4224	UPF0291 protein
AS891_14410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_14415	COG1388	LysM domain
AS891_14420	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AS891_14430	COG0346	lactoylglutathione lyase activity
AS891_14440	COG4195	phage-related replication protein
AS891_14470	COG0531	amino acid
AS891_14475	COG0697	spore germination
AS891_14490	COG3832	glyoxalase III activity
AS891_14505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS891_14530	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS891_14540	COG0756	dUTP diphosphatase activity
AS891_14550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS891_14555	COG2814	Major facilitator Superfamily
AS891_14560	COG1525	nuclease
AS891_14565	COG1070	Carbohydrate kinase
AS891_14570	COG2115	Belongs to the xylose isomerase family
AS891_14575	COG1940	carbohydrate kinase activity
AS891_14580	COG3507	Belongs to the glycosyl hydrolase 43 family
AS891_14585	COG2211	Major facilitator Superfamily
AS891_14590	COG0135	phosphoribosylanthranilate isomerase activity
AS891_14615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_14625	COG4282	regulation of fungal-type cell wall biogenesis
AS891_14645	COG0174	glutamine synthetase
AS891_14650	COG0789	Transcriptional regulator
AS891_14655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AS891_14660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS891_14670	COG0464	growth
AS891_14675	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS891_14680	COG4112	unkown
AS891_14685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_14690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS891_14695	COG1780	Probably involved in ribonucleotide reductase function
AS891_14710	COG1923	regulation of RNA biosynthetic process
AS891_14715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AS891_14730	COG2076	Multidrug Resistance protein
AS891_14735	COG2076	Multidrug Resistance protein
AS891_14740	COG1764	response to oxidative stress
AS891_14745	COG4195	phage-related replication protein
AS891_14755	COG1404	Belongs to the peptidase S8 family
AS891_14760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_14770	COG2124	cytochrome p450
AS891_14775	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AS891_14775	COG3321	synthase
AS891_14775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS891_14775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_14780	COG3321	synthase
AS891_14780	COG4221	oxidoreductase activity
AS891_14780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14780	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_14785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_14785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_14785	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_14785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14785	COG3321	synthase
AS891_14790	COG0300	oxidoreductase activity
AS891_14790	COG3321	synthase
AS891_14790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_14790	COG4221	oxidoreductase activity
AS891_14795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS891_14795	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_14795	COG0300	oxidoreductase activity
AS891_14795	COG3321	synthase
AS891_14795	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_14800	COG1024	Enoyl-CoA hydratase
AS891_14805	COG1024	Enoyl-CoA hydratase
AS891_14810	COG3425	synthase
AS891_14815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS891_14820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_14830	COG3321	synthase
AS891_14835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS891_14845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_14850	COG3226	Transcriptional regulator
AS891_14870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AS891_14875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AS891_14885	COG4550	Control of competence regulator ComK, YlbF/YmcA
AS891_14890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS891_14895	COG0156	8-amino-7-oxononanoate synthase activity
AS891_14900	COG1063	alcohol dehydrogenase
AS891_14905	COG2359	stage V sporulation protein S
AS891_14910	COG1692	metallophosphoesterase
AS891_14915	COG1418	mRNA catabolic process
AS891_14920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS891_14925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AS891_14930	COG1058	Belongs to the CinA family
AS891_14930	COG1546	Belongs to the CinA family
AS891_14935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS891_14940	COG1426	Protein conserved in bacteria
AS891_14955	COG0300	oxidoreductase activity
AS891_14960	COG0612	Peptidase, M16
AS891_14965	COG0612	Peptidase, M16
AS891_14970	COG2814	Major facilitator Superfamily
AS891_14975	COG2188	Transcriptional regulator
AS891_14980	COG4980	gas vesicle protein
AS891_14980	COG1674	ftsk spoiiie
AS891_14990	COG0740	serine-type endopeptidase activity
AS891_14995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS891_15000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS891_15005	COG0527	aspartate kinase activity
AS891_15010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS891_15015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS891_15020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS891_15030	COG1873	PFAM PRC-barrel domain
AS891_15035	COG0612	Peptidase, M16
AS891_15040	COG0726	polysaccharide deacetylase
AS891_15045	COG1185	polyribonucleotide nucleotidyltransferase activity
AS891_15050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AS891_15055	COG0196	riboflavin kinase activity
AS891_15060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AS891_15065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AS891_15070	COG1550	Protein conserved in bacteria
AS891_15075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AS891_15080	COG1358	cellular component organization or biogenesis
AS891_15085	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AS891_15090	COG0195	Participates in both transcription termination and antitermination
AS891_15095	COG0779	Required for maturation of 30S ribosomal subunits
AS891_15100	COG2176	DNA-directed DNA polymerase activity
AS891_15105	COG0442	prolyl-tRNA aminoacylation
AS891_15110	COG0750	zinc metalloprotease
AS891_15115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AS891_15120	COG4589	Belongs to the CDS family
AS891_15125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AS891_15130	COG0233	cytoplasmic translational termination
AS891_15135	COG0528	UMP kinase activity
AS891_15140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AS891_15145	COG0052	Belongs to the universal ribosomal protein uS2 family
AS891_15155	COG1191	sigma factor activity
AS891_15160	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AS891_15165	COG1776	CheC inhibitor of MCP methylation
AS891_15170	COG0835	chemotaxis
AS891_15175	COG0643	Histidine kinase
AS891_15175	COG2198	Histidine kinase
AS891_15180	COG2201	protein-glutamate methylesterase activity
AS891_15185	COG0455	bacterial-type flagellum organization
AS891_15190	COG1419	protein localization to endoplasmic reticulum
AS891_15195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS891_15200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS891_15205	COG1684	flagellar biosynthetic protein fliR
AS891_15210	COG1987	bacterial-type flagellum assembly
AS891_15215	COG1338	Plays a role in the flagellum-specific transport system
AS891_15220	COG3190	flagellar
AS891_15225	COG2201	protein-glutamate methylesterase activity
AS891_15230	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS891_15230	COG1776	CheC inhibitor of MCP methylation
AS891_15235	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS891_15240	COG1580	Controls the rotational direction of flagella during chemotaxis
AS891_15245	COG1582	Flagellar protein (FlbD)
AS891_15250	COG4786	Flagellar basal body rod
AS891_15255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AS891_15260	COG3144	bacterial-type flagellum assembly
AS891_15265	COG3334	PFAM MgtE intracellular
AS891_15270	COG2882	bacterial-type flagellum organization
AS891_15275	COG1157	protein secretion by the type III secretion system
AS891_15280	COG1317	bacterial-type flagellum organization
AS891_15285	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS891_15290	COG1766	The M ring may be actively involved in energy transduction
AS891_15295	COG1677	Flagellar hook-basal body complex protein FliE
AS891_15300	COG1558	bacterial-type flagellum-dependent cell motility
AS891_15305	COG1815	bacterial-type flagellum-dependent cell motility
AS891_15310	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AS891_15315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AS891_15320	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AS891_15325	COG4974	Belongs to the 'phage' integrase family
AS891_15330	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AS891_15335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS891_15340	COG0758	DNA mediated transformation
AS891_15345	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AS891_15350	COG0045	succinate-CoA ligase (ADP-forming) activity
AS891_15355	COG2257	FlhB HrpN YscU SpaS Family
AS891_15365	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AS891_15370	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS891_15375	COG0335	large ribosomal subunit rRNA binding
AS891_15380	COG0336	Belongs to the RNA methyltransferase TrmD family
AS891_15385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AS891_15395	COG1837	Belongs to the UPF0109 family
AS891_15400	COG0228	four-way junction DNA binding
AS891_15405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS891_15410	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AS891_15420	COG0552	protein localization to endoplasmic reticulum
AS891_15425	COG1196	nuclear chromosome segregation
AS891_15430	COG0571	ribonuclease III activity
AS891_15435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS891_15440	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_15445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS891_15450	COG0416	fatty acid biosynthetic process
AS891_15455	COG2050	protein possibly involved in aromatic compounds catabolism
AS891_15455	COG1349	DNA-binding transcription factor activity
AS891_15460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS891_15465	COG1760	l-serine dehydratase
AS891_15470	COG1760	l-serine dehydratase
AS891_15475	COG1461	Dihydroxyacetone kinase
AS891_15480	COG1302	Protein conserved in bacteria
AS891_15485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AS891_15495	COG1564	THIamine pyrophosphokinase
AS891_15500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS891_15505	COG1162	GTPase activity
AS891_15510	COG2815	serine threonine protein kinase
AS891_15510	COG0515	serine threonine protein kinase
AS891_15515	COG0631	protein serine/threonine phosphatase activity
AS891_15520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AS891_15525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS891_15525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS891_15530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS891_15535	COG0242	peptide deformylase activity
AS891_15540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS891_15545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS891_15550	COG1758	RNA polymerase activity
AS891_15555	COG0194	GDP metabolic process
AS891_15560	COG2052	Domain of unknown function (DUF370)
AS891_15565	COG1561	YicC-like family, N-terminal region
AS891_15570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS891_15580	COG1648	precorrin-2 dehydrogenase activity
AS891_15585	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AS891_15590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS891_15595	COG0529	Catalyzes the synthesis of activated sulfate
AS891_15600	COG2046	Belongs to the sulfate adenylyltransferase family
AS891_15605	COG0306	phosphate transporter
AS891_15610	COG0175	sulfate reduction
AS891_15615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AS891_15620	COG0284	orotidine-5'-phosphate decarboxylase activity
AS891_15625	COG0167	dihydroorotate dehydrogenase activity
AS891_15630	COG0543	2 iron, 2 sulfur cluster binding
AS891_15635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS891_15640	COG0505	Belongs to the CarA family
AS891_15645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AS891_15650	COG0540	Belongs to the ATCase OTCase family
AS891_15655	COG2233	PERMEase
AS891_15660	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AS891_15665	COG0564	pseudouridine synthase activity
AS891_15670	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AS891_15675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS891_15680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AS891_15685	COG3599	regulation of cell shape
AS891_15690	COG2302	S4 RNA-binding domain
AS891_15695	COG0762	integral membrane protein
AS891_15700	COG1799	cell septum assembly
AS891_15705	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AS891_15715	COG1873	PFAM PRC-barrel domain
AS891_15720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS891_15725	COG1119	ATPase activity
AS891_15730	COG1191	sigma factor activity
AS891_15735	COG1191	sigma factor activity
AS891_15745	COG4412	M6 family metalloprotease domain protein
AS891_15745	COG1404	Belongs to the peptidase S8 family
AS891_15750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS891_15755	COG0849	cell division
AS891_15760	COG3856	small basic protein
AS891_15765	COG3879	Bacterial protein of unknown function (DUF881)
AS891_15770	COG3879	Bacterial protein of unknown function (DUF881)
AS891_15775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS891_15780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AS891_15785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS891_15790	COG0772	Belongs to the SEDS family
AS891_15795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AS891_15800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS891_15810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AS891_15820	COG0768	penicillin binding
AS891_15835	COG4839	cell division protein FtsL
AS891_15840	COG0275	rRNA processing
AS891_15845	COG2001	Belongs to the MraZ family
AS891_15850	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AS891_15855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS891_15860	COG0454	-acetyltransferase
AS891_15870	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AS891_15875	COG1399	metal-binding, possibly nucleic acid-binding protein
AS891_15885	COG1323	Belongs to the UPF0348 family
AS891_15890	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS891_15895	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS891_15900	COG3314	Sporulation integral membrane protein YlbJ
AS891_15905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AS891_15910	COG0742	ribosomal rna small subunit methyltransferase
AS891_15915	COG4471	UPF0298 protein
AS891_15920	COG3679	Belongs to the UPF0342 family
AS891_15935	COG2340	Cysteine-rich secretory protein family
AS891_15940	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AS891_15950	COG3336	cytochrome c oxidase
AS891_15955	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AS891_15960	COG1845	cytochrome c oxidase, subunit III
AS891_15965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS891_15970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS891_15970	COG2010	Cytochrome c
AS891_15975	COG0109	protoheme IX farnesyltransferase activity
AS891_15980	COG1612	heme a metabolic process
AS891_15985	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS891_15990	COG0772	Belongs to the SEDS family
AS891_15995	COG4838	Belongs to the UPF0358 family
AS891_16000	COG2066	Belongs to the glutaminase family
AS891_16005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS891_16010	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS891_16020	COG4896	Protein conserved in bacteria
AS891_16050	COG1595	DNA-templated transcription, initiation
AS891_16070	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS891_16080	COG0483	inositol monophosphate 1-phosphatase activity
AS891_16090	COG4493	Belongs to the UPF0637 family
AS891_16095	COG4476	Belongs to the UPF0223 family
AS891_16100	COG1982	Orn Lys Arg decarboxylase major
AS891_16105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_16110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS891_16115	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_16120	COG0022	dehydrogenase e1 component
AS891_16125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS891_16130	COG0497	DNA recombination
AS891_16140	COG0242	peptide deformylase activity
AS891_16145	COG0561	phosphatase activity
AS891_16155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS891_16160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS891_16165	COG0569	domain protein
AS891_16170	COG2105	PFAM AIG2 family protein
AS891_16170	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AS891_16175	COG3852	Histidine kinase
AS891_16180	COG2002	toxin-antitoxin pair type II binding
AS891_16185	COG1077	Cell shape determining protein MreB Mrl
AS891_16195	COG2309	aminopeptidase activity
AS891_16200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS891_16205	COG0488	(ABC) transporter
AS891_16215	COG0681	Belongs to the peptidase S26 family
AS891_16220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_16220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_16220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_16225	COG1105	Belongs to the carbohydrate kinase PfkB family
AS891_16230	COG1349	DNA-binding transcription factor activity
AS891_16235	COG0577	efflux transmembrane transporter activity
AS891_16240	COG1136	(ABC) transporter
AS891_16245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AS891_16255	COG1132	(ABC) transporter
AS891_16260	COG1132	(ABC) transporter
AS891_16265	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AS891_16270	COG0314	molybdopterin synthase activity
AS891_16275	COG1763	Mo-molybdopterin cofactor biosynthetic process
AS891_16280	COG0303	'Molybdopterin
AS891_16285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS891_16290	COG0746	molybdenum cofactor guanylyltransferase activity
AS891_16305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_16310	COG0450	alkyl hydroperoxide reductase
AS891_16315	COG0668	transmembrane transport
AS891_16325	COG1473	amidohydrolase
AS891_16330	COG2171	N-acyltransferase activity
AS891_16335	COG0716	FMN binding
AS891_16345	COG0716	FMN binding
AS891_16350	COG0583	DNA-binding transcription factor activity
AS891_16355	COG0517	IMP dehydrogenase activity
AS891_16365	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AS891_16370	COG4703	Protein of unknown function (DUF1797)
AS891_16380	COG2200	EAL domain
AS891_16390	COG3409	Peptidoglycan-binding domain 1 protein
AS891_16395	COG3409	Peptidoglycan-binding domain 1 protein
AS891_16400	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_16405	COG1408	metallophosphoesterase
AS891_16410	COG1376	ErfK ybiS ycfS ynhG family protein
AS891_16415	COG2814	Major facilitator Superfamily
AS891_16425	COG0835	chemotaxis
AS891_16425	COG0784	Response regulator, receiver
AS891_16435	COG0436	Aminotransferase
AS891_16440	COG4191	Histidine kinase
AS891_16445	COG0768	penicillin binding
AS891_16450	COG2340	Cysteine-rich secretory protein family
AS891_16455	COG2084	Dehydrogenase
AS891_16460	COG0840	transmembrane signaling receptor activity
AS891_16465	COG0456	acetyltransferase
AS891_16470	COG1533	DNA photolyase activity
AS891_16480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AS891_16485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_16490	COG2190	(PTS) system
AS891_16490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_16490	COG1263	PTS System
AS891_16495	COG3711	transcriptional antiterminator
AS891_16500	COG1609	Transcriptional regulator
AS891_16510	COG0006	proline dipeptidase activity
AS891_16520	COG2217	Heavy metal translocating P-type atpase
AS891_16525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_16530	COG2244	polysaccharide biosynthetic process
AS891_16535	COG3773	Cell wall hydrolase
AS891_16550	COG4873	Protein conserved in bacteria
AS891_16560	COG3858	chitin binding
AS891_16565	COG3858	chitin binding
AS891_16570	COG1388	LysM domain
AS891_16575	COG1388	LysM domain
AS891_16575	COG4641	Protein conserved in bacteria
AS891_16580	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_16585	COG1733	regulation of RNA biosynthetic process
AS891_16590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AS891_16595	COG0602	queuosine metabolic process
AS891_16600	COG0720	synthase
AS891_16605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AS891_16610	COG3949	Membrane
AS891_16615	COG0542	response to heat
AS891_16620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS891_16625	COG1360	Flagellar Motor Protein
AS891_16630	COG1846	Transcriptional regulator
AS891_16635	COG3852	Histidine kinase
AS891_16650	COG3339	Conserved Protein
AS891_16655	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AS891_16660	COG0235	Class ii aldolase
AS891_16665	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AS891_16670	COG1850	ribulose-bisphosphate carboxylase activity
AS891_16675	COG0436	Aminotransferase
AS891_16680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS891_16685	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AS891_16690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AS891_16700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS891_16705	COG5002	protein histidine kinase activity
AS891_16710	COG3594	Acyltransferase
AS891_16725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS891_16730	COG0501	Belongs to the peptidase M48B family
AS891_16750	COG1191	sigma factor activity
AS891_16755	COG0861	Integral membrane protein TerC family
AS891_16760	COG0586	Pfam SNARE associated Golgi protein
AS891_16765	COG3300	MHYT domain
AS891_16765	COG5001	Diguanylate cyclase
AS891_16770	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AS891_16775	COG3285	dna ligase
AS891_16775	COG1793	dna ligase
AS891_16780	COG0463	Glycosyl transferase, family 2
AS891_16790	COG1408	metallophosphoesterase
AS891_16795	COG0726	polysaccharide deacetylase
AS891_16800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS891_16805	COG1846	Transcriptional regulator
AS891_16820	COG0789	Transcriptional regulator
AS891_16825	COG2239	Acts as a magnesium transporter
AS891_16845	COG3212	peptidase
AS891_16850	COG3212	peptidase
AS891_16855	COG5002	protein histidine kinase activity
AS891_16855	COG3850	Histidine kinase
AS891_16860	COG0745	RESPONSE REGULATOR receiver
AS891_16870	COG4721	ABC-type cobalt transport system, permease component
AS891_16875	COG1122	ATPase activity
AS891_16880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS891_16885	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_16890	COG1404	Belongs to the peptidase S8 family
AS891_16895	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AS891_16900	COG0590	tRNA wobble adenosine to inosine editing
AS891_16910	COG1764	response to oxidative stress
AS891_16915	COG1846	Transcriptional regulator
AS891_16920	COG1764	response to oxidative stress
AS891_16925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AS891_16930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AS891_16935	COG0788	formyltetrahydrofolate deformylase activity
AS891_16940	COG2076	Multidrug Resistance protein
AS891_16945	COG2076	Multidrug Resistance protein
AS891_16950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_16955	COG2318	DinB family
AS891_16960	COG2323	membrane
AS891_16970	COG1017	nitric oxide dioxygenase activity
AS891_16970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AS891_16975	COG1607	acyl-coa hydrolase
AS891_16980	COG1834	amidinotransferase
AS891_16985	COG2706	6-phosphogluconolactonase activity
AS891_16990	COG4608	Belongs to the ABC transporter superfamily
AS891_16995	COG0791	NLP P60 protein
AS891_17000	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_17005	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS891_17010	COG4166	transmembrane transport
AS891_17015	COG0444	Belongs to the ABC transporter superfamily
AS891_17020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS891_17025	COG0601	transmembrane transport
AS891_17030	COG2362	D-Aminopeptidase
AS891_17035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS891_17040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS891_17050	COG0463	Glycosyl transferase, family 2
AS891_17055	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AS891_17060	COG0346	lactoylglutathione lyase activity
AS891_17065	COG0531	amino acid
AS891_17070	COG1392	Phosphate transport regulator
AS891_17075	COG0306	phosphate transporter
AS891_17090	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_17090	COG3409	Peptidoglycan-binding domain 1 protein
AS891_17130	COG3778	Protein conserved in bacteria
AS891_17135	COG3299	homolog of phage Mu protein gp47
AS891_17140	COG3628	GPW Gp25 family protein
AS891_17150	COG4193	domain, Protein
AS891_17155	COG1652	LysM domain
AS891_17160	COG5412	phage tail tape measure protein
AS891_17160	COG3953	SLT domain
AS891_17210	COG4653	Phage capsid family
AS891_17215	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AS891_17220	COG5518	Phage portal protein
AS891_17225	COG1783	phage Terminase large subunit
AS891_17230	COG5484	DNA packaging
AS891_17230	COG3728	DNA packaging
AS891_17235	COG1595	DNA-templated transcription, initiation
AS891_17260	COG1484	DNA-dependent DNA replication
AS891_17265	COG1522	sequence-specific DNA binding
AS891_17275	COG1396	sequence-specific DNA binding
AS891_17280	COG2856	Zn peptidase
AS891_17285	COG3546	catalase activity
AS891_17290	COG4195	phage-related replication protein
AS891_17300	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS891_17300	COG1388	LysM domain
AS891_17300	COG3409	Peptidoglycan-binding domain 1 protein
AS891_17305	COG2350	Protein conserved in bacteria
AS891_17315	COG0457	Tetratricopeptide repeat
AS891_17320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS891_17325	COG2318	DinB family
AS891_17330	COG0730	response to heat
AS891_17335	COG2721	sulfolactate sulfo-lyase activity
AS891_17340	COG0246	Mannitol dehydrogenase
AS891_17345	COG1609	Transcriptional regulator
AS891_17350	COG2271	Major facilitator Superfamily
AS891_17355	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_17360	COG1312	Catalyzes the dehydration of D-mannonate
AS891_17365	COG1063	alcohol dehydrogenase
AS891_17370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AS891_17375	COG2211	Major facilitator Superfamily
AS891_17380	COG1904	glucuronate isomerase
AS891_17385	COG1252	NADH dehydrogenase
AS891_17395	COG4297	protein containing double-stranded beta helix domain
AS891_17400	COG0697	spore germination
AS891_17405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AS891_17410	COG0390	transport system, permease component
AS891_17415	COG1587	Uroporphyrinogen-III synthase
AS891_17425	COG1819	glycosyl
AS891_17430	COG2124	cytochrome p450
AS891_17440	COG1051	belongs to the nudix hydrolase family
AS891_17450	COG2427	Protein of unknown function (DUF1641)
AS891_17455	COG3383	formate dehydrogenase (NAD+) activity
AS891_17465	COG2205	protein histidine kinase activity
AS891_17470	COG5504	Zn-dependent protease
AS891_17490	COG0726	polysaccharide deacetylase
AS891_17500	COG0109	protoheme IX farnesyltransferase activity
AS891_17515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS891_17525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_17535	COG1482	cell wall glycoprotein biosynthetic process
AS891_17540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_17540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_17540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS891_17545	COG3711	transcriptional antiterminator
AS891_17545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_17555	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_17560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AS891_17565	COG5484	DNA packaging
AS891_17580	COG3677	Transposase
AS891_17615	COG5505	Protein of unknown function (DUF819)
AS891_17620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_17625	COG0626	cystathionine gamma-synthase activity
AS891_17630	COG0626	cystathionine gamma-synthase activity
AS891_17635	COG2382	esterase
AS891_17640	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AS891_17645	COG2153	protein acetylation
AS891_17655	COG0210	DNA helicase
AS891_17715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AS891_17720	COG0351	phosphomethylpyrimidine kinase
AS891_17725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS891_17730	COG2022	thiamine diphosphate biosynthetic process
AS891_17735	COG2104	thiamine diphosphate biosynthetic process
AS891_17740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS891_17745	COG0352	thiamine-phosphate diphosphorylase activity
AS891_17750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS891_17755	COG0569	domain protein
AS891_17755	COG0475	glutathione-regulated potassium exporter activity
AS891_17760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS891_17765	COG0564	pseudouridine synthase activity
AS891_17770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AS891_17775	COG2357	RelA SpoT domain protein
AS891_17785	COG4116	CYTH
AS891_17790	COG0741	lytic transglycosylase activity
AS891_17795	COG2346	COG2346, Truncated hemoglobins
AS891_17815	COG1164	Oligoendopeptidase f
AS891_17820	COG4469	Competence protein
AS891_17825	COG4862	establishment of competence for transformation
AS891_17830	COG0861	Integral membrane protein TerC family
AS891_17835	COG1393	Belongs to the ArsC family
AS891_17840	COG0456	acetyltransferase
AS891_17845	COG2814	Major facilitator Superfamily
AS891_17850	COG4608	Belongs to the ABC transporter superfamily
AS891_17855	COG0444	Belongs to the ABC transporter superfamily
AS891_17860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS891_17865	COG0601	transmembrane transport
AS891_17875	COG0180	Tryptophanyl-tRNA synthetase
AS891_17885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS891_17890	COG0601	transmembrane transport
AS891_17900	COG4608	Belongs to the ABC transporter superfamily
AS891_17905	COG0444	Belongs to the ABC transporter superfamily
AS891_17910	COG5504	Zn-dependent protease
AS891_17915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS891_17920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS891_17935	COG1744	ABC transporter substrate-binding protein PnrA-like
AS891_17945	COG2267	carboxylic ester hydrolase activity
AS891_17960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AS891_17965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AS891_17970	COG0505	Belongs to the CarA family
AS891_17975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS891_17990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AS891_17995	COG2271	Major facilitator Superfamily
AS891_18000	COG0277	FAD linked oxidase domain protein
AS891_18010	COG2151	metal-sulfur cluster biosynthetic enzyme
AS891_18015	COG1073	alpha beta
AS891_18020	COG0561	phosphatase activity
AS891_18040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_18045	COG1307	EDD domain protein, DegV family
AS891_18050	COG3227	Zinc metalloprotease (Elastase)
AS891_18065	COG1695	Transcriptional regulator
AS891_18085	COG2996	Protein conserved in bacteria
AS891_18090	COG1666	GTP binding
AS891_18095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS891_18095	COG0646	methionine synthase
AS891_18100	COG2153	protein acetylation
AS891_18105	COG0454	-acetyltransferase
AS891_18110	COG2814	Major facilitator Superfamily
AS891_18115	COG4948	Mandelate Racemase Muconate Lactonizing
AS891_18120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_18125	COG1809	phosphosulfolactate synthase activity
AS891_18130	COG2045	Belongs to the ComB family
AS891_18135	COG0175	sulfate reduction
AS891_18140	COG2046	Belongs to the sulfate adenylyltransferase family
AS891_18145	COG0529	Catalyzes the synthesis of activated sulfate
AS891_18150	COG2267	carboxylic ester hydrolase activity
AS891_18155	COG1357	PFAM Pentapeptide repeats (8 copies)
AS891_18160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_18165	COG1279	arginine transmembrane transporter activity
AS891_18170	COG2318	DinB family
AS891_18175	COG0673	inositol 2-dehydrogenase activity
AS891_18180	COG1609	Transcriptional regulator
AS891_18185	COG2207	Transcriptional regulator
AS891_18185	COG1917	Cupin 2, conserved barrel domain protein
AS891_18190	COG0534	Mate efflux family protein
AS891_18195	COG1562	ergosterol biosynthetic process
AS891_18200	COG2318	DinB family
AS891_18205	COG0367	asparagine synthase
AS891_18215	COG1404	Belongs to the peptidase S8 family
AS891_18225	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS891_18230	COG5337	Spore coat protein CotH
AS891_18275	COG1403	HNH endonuclease
AS891_18280	COG0419	ATPase involved in DNA repair
AS891_18285	COG0420	3'-5' exonuclease activity
AS891_18290	COG1074	ATP-dependent DNA helicase activity
AS891_18295	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AS891_18300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AS891_18310	COG4533	DNA binding
AS891_18315	COG0477	Major facilitator Superfamily
AS891_18315	COG2814	Major facilitator Superfamily
AS891_18320	COG3180	Ammonia monooxygenase
AS891_18325	COG1609	Transcriptional regulator
AS891_18330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS891_18335	COG0561	phosphatase activity
AS891_18340	COG0673	inositol 2-dehydrogenase activity
AS891_18345	COG0738	Major facilitator superfamily
AS891_18350	COG1846	Transcriptional regulator
AS891_18355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS891_18360	COG0681	Belongs to the peptidase S26 family
AS891_18365	COG0398	Pfam SNARE associated Golgi protein
AS891_18380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_18390	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_18395	COG4903	ComK protein
AS891_18405	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_18410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS891_18410	COG0723	plastoquinol--plastocyanin reductase activity
AS891_18415	COG0840	transmembrane signaling receptor activity
AS891_18420	COG1268	BioY protein
AS891_18425	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_18430	COG0183	Belongs to the thiolase family
AS891_18435	COG0406	alpha-ribazole phosphatase activity
AS891_18440	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS891_18445	COG0604	alcohol dehydrogenase
AS891_18450	COG0456	acetyltransferase
AS891_18455	COG1404	Belongs to the peptidase S8 family
AS891_18460	COG0501	Belongs to the peptidase M48B family
AS891_18470	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_18475	COG0702	epimerase
AS891_18480	COG0095	Lipoate-protein ligase
AS891_18485	COG1234	tRNA 3'-trailer cleavage
AS891_18495	COG1301	dicarboxylic acid transport
AS891_18500	COG4405	Protein conserved in bacteria
AS891_18505	COG1363	Peptidase, m42
AS891_18515	COG4377	Putative membrane peptidase family (DUF2324)
AS891_18520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS891_18525	COG1511	domain protein
AS891_18530	COG1309	transcriptional regulator
AS891_18545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AS891_18550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS891_18555	COG2329	Antibiotic biosynthesis monooxygenase
AS891_18565	COG3069	C4-dicarboxylate transmembrane transporter activity
AS891_18570	COG1473	amidohydrolase
AS891_18580	COG4473	ABC transporter
AS891_18585	COG1131	(ABC) transporter
AS891_18590	COG0537	adenosine 5'-monophosphoramidase activity
AS891_18595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AS891_18610	COG4980	gas vesicle protein
AS891_18615	COG1846	Transcriptional regulator
AS891_18635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AS891_18645	COG3481	metal-dependent phosphohydrolase, HD sub domain
AS891_18650	COG4717	serine-type aminopeptidase activity
AS891_18655	COG0420	3'-5' exonuclease activity
AS891_18660	COG1668	transmembrane transport
AS891_18665	COG4152	abc transporter atp-binding protein
AS891_18675	COG1024	Enoyl-CoA hydratase
AS891_18685	COG0490	domain, Protein
AS891_18690	COG0475	glutathione-regulated potassium exporter activity
AS891_18695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS891_18700	COG0561	phosphatase activity
AS891_18705	COG4335	DNA alkylation repair
AS891_18710	COG3679	Belongs to the UPF0342 family
AS891_18715	COG4399	Belongs to the UPF0754 family
AS891_18720	COG0189	ligase activity
AS891_18725	COG0189	ligase activity
AS891_18740	COG0702	epimerase
AS891_18745	COG1132	(ABC) transporter
AS891_18750	COG1132	(ABC) transporter
AS891_18760	COG0589	response to stress
AS891_18765	COG1757	Na H antiporter
AS891_18770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS891_18775	COG0726	polysaccharide deacetylase
AS891_18780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS891_18785	COG0668	transmembrane transport
AS891_18795	COG0584	glycerophosphoryl diester phosphodiesterase
AS891_18800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS891_18805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AS891_18810	COG1253	flavin adenine dinucleotide binding
AS891_18815	COG0436	Aminotransferase
AS891_18820	COG0789	Transcriptional regulator
AS891_18825	COG1253	flavin adenine dinucleotide binding
AS891_18830	COG0204	Acyl-transferase
AS891_18835	COG0667	Aldo Keto reductase
AS891_18840	COG1595	DNA-templated transcription, initiation
AS891_18855	COG0456	acetyltransferase
AS891_18860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_18865	COG0733	neurotransmitter:sodium symporter activity
AS891_18870	COG0531	amino acid
AS891_18875	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_18880	COG0372	Belongs to the citrate synthase family
AS891_18885	COG0583	DNA-binding transcription factor activity
AS891_18890	COG0791	NLP P60 protein
AS891_18890	COG1388	LysM domain
AS891_18895	COG1785	Belongs to the alkaline phosphatase family
AS891_18900	COG2719	SpoVR family
AS891_18905	COG0668	transmembrane transport
AS891_18910	COG1959	2 iron, 2 sulfur cluster binding
AS891_18915	COG0791	NLP P60 protein
AS891_18915	COG1388	LysM domain
AS891_18930	COG0431	NADPH-dependent FMN reductase
AS891_18935	COG2197	response regulator
AS891_18940	COG2203	Gaf domain
AS891_18940	COG4585	Histidine kinase
AS891_18945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS891_18950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS891_18955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AS891_18960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS891_18965	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS891_18970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS891_18975	COG3153	acetyltransferase
AS891_18975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS891_18980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS891_18985	COG0517	IMP dehydrogenase activity
AS891_18995	COG0564	pseudouridine synthase activity
AS891_19000	COG3764	Sortase (surface protein transpeptidase)
AS891_19005	COG0737	Belongs to the 5'-nucleotidase family
AS891_19005	COG4085	toxin activity
AS891_19005	COG1525	nuclease
AS891_19010	COG5577	PFAM Coat F domain
AS891_19030	COG1823	symporter activity
AS891_19035	COG3706	GGDEF domain
AS891_19040	COG1464	Belongs to the NlpA lipoprotein family
AS891_19050	COG1278	Cold shock
AS891_19055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS891_19060	COG1131	(ABC) transporter
AS891_19065	COG1131	(ABC) transporter
AS891_19070	COG1725	Transcriptional regulator
AS891_19085	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS891_19090	COG2814	Major facilitator Superfamily
AS891_19095	COG1566	PFAM secretion protein HlyD family protein
AS891_19100	COG1846	Transcriptional regulator
AS891_19110	COG2718	Belongs to the UPF0229 family
AS891_19115	COG2766	serine protein kinase
AS891_19120	COG1664	Polymer-forming cytoskeletal
AS891_19125	COG1664	Polymer-forming cytoskeletal
AS891_19130	COG0789	Transcriptional regulator
AS891_19135	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AS891_19145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AS891_19150	COG3382	B3 4 domain protein
AS891_19160	COG1476	TRANSCRIPTIONal
AS891_19170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AS891_19180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_19185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS891_19190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS891_19195	COG1116	anion transmembrane transporter activity
AS891_19200	COG0753	catalase activity
AS891_19210	COG0277	FAD linked oxidase domain protein
AS891_19215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AS891_19220	COG3340	Belongs to the peptidase S51 family
AS891_19225	COG5577	PFAM Coat F domain
AS891_19235	COG4326	sporulation control protein
AS891_19350	COG0735	belongs to the Fur family
AS891_19355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS891_19360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AS891_19365	COG4129	membrane
AS891_19370	COG1132	(ABC) transporter
AS891_19375	COG3557	Belongs to the UPF0374 family
AS891_19390	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_19400	COG1194	a g-specific adenine glycosylase
AS891_19405	COG1988	membrane-bound metal-dependent
AS891_19410	COG4485	Bacterial membrane protein, YfhO
AS891_19415	COG0463	Glycosyl transferase, family 2
AS891_19420	COG0596	Alpha beta hydrolase
AS891_19425	COG5658	integral membrane protein
AS891_19430	COG3103	Sh3 type 3 domain protein
AS891_19445	COG2814	Major facilitator Superfamily
AS891_19460	COG2137	regulation of response to DNA damage stimulus
AS891_19465	COG1090	epimerase
AS891_19480	COG0778	Nitroreductase
AS891_19485	COG0384	phenazine biosynthesis protein PhzF
AS891_19490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_19495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_19500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS891_19505	COG0392	lysyltransferase activity
AS891_19505	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS891_19510	COG1846	Transcriptional regulator
AS891_19515	COG2814	Major facilitator Superfamily
AS891_19520	COG2318	DinB family
AS891_19525	COG2814	Major facilitator Superfamily
AS891_19530	COG1309	transcriptional regulator
AS891_19535	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AS891_19540	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AS891_19545	COG1695	Transcriptional regulator
AS891_19550	COG0842	Transport permease protein
AS891_19555	COG0842	Transport permease protein
AS891_19555	COG1511	domain protein
AS891_19560	COG1131	(ABC) transporter
AS891_19565	COG2197	response regulator
AS891_19570	COG4585	Histidine kinase
AS891_19575	COG0673	inositol 2-dehydrogenase activity
AS891_19580	COG1082	Xylose isomerase domain protein TIM barrel
AS891_19585	COG2814	Major facilitator Superfamily
AS891_19590	COG4977	sequence-specific DNA binding
AS891_19590	COG1917	Cupin 2, conserved barrel domain protein
AS891_19595	COG2514	catechol 2,3-dioxygenase activity
AS891_19600	COG2259	Doxx family
AS891_19605	COG1132	(ABC) transporter
AS891_19610	COG1132	(ABC) transporter
AS891_19615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_19615	COG1263	PTS System
AS891_19620	COG1737	Transcriptional regulator
AS891_19625	COG1486	melibiose metabolic process
AS891_19630	COG4842	Belongs to the WXG100 family
AS891_19655	COG1742	UPF0060 membrane protein
AS891_19665	COG3284	Transcriptional regulator
AS891_19670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS891_19675	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS891_19680	COG0022	dehydrogenase e1 component
AS891_19685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS891_19695	COG4637	Psort location Cytoplasmic, score
AS891_19700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS891_19710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS891_19715	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS891_19720	COG0598	Magnesium transport protein CorA
AS891_19725	COG2084	Dehydrogenase
AS891_19730	COG0726	polysaccharide deacetylase
AS891_19740	COG0535	radical SAM domain protein
AS891_19745	COG0668	transmembrane transport
AS891_19755	COG0387	Pfam Sodium calcium exchanger
AS891_19765	COG0477	Major facilitator Superfamily
AS891_19775	COG1295	ribonuclease BN
AS891_19780	COG4980	gas vesicle protein
AS891_19785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS891_19790	COG4840	Belongs to the UPF0435 family
AS891_19795	COG2814	Major facilitator Superfamily
AS891_19800	COG0693	protein deglycase activity
AS891_19805	COG0737	Belongs to the 5'-nucleotidase family
AS891_19810	COG0778	Nitroreductase
AS891_19815	COG2188	Transcriptional regulator
AS891_19820	COG0366	Alpha amylase catalytic
AS891_19825	COG1263	PTS System
AS891_19825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_19830	COG0697	spore germination
AS891_19845	COG0531	amino acid
AS891_19850	COG1115	amino acid carrier protein
AS891_19860	COG1368	sulfuric ester hydrolase activity
AS891_19865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS891_19865	COG1263	PTS System
AS891_19870	COG0024	Methionine aminopeptidase
AS891_19890	COG2258	MOSC domain
AS891_19895	COG1254	Belongs to the acylphosphatase family
AS891_19900	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AS891_19905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS891_19910	COG2851	Citrate transporter
AS891_19920	COG3181	Tripartite tricarboxylate transporter family receptor
AS891_19925	COG4565	transcriptional regulatory protein
AS891_19930	COG3290	protein histidine kinase activity
AS891_19935	COG0471	metal ion transport
AS891_19940	COG3866	Pectate lyase
AS891_19955	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS891_19960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_19965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_19970	COG1120	ATPase activity
AS891_19975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AS891_19980	COG2211	Major facilitator Superfamily
AS891_19995	COG2130	NADP-dependent
AS891_20000	COG0456	acetyltransferase
AS891_20005	COG0513	Belongs to the DEAD box helicase family
AS891_20010	COG0488	(ABC) transporter
AS891_20025	COG2814	Major facilitator Superfamily
AS891_20030	COG0789	Transcriptional regulator
AS891_20040	COG0488	(ABC) transporter
AS891_20045	COG0840	transmembrane signaling receptor activity
AS891_20050	COG1012	belongs to the aldehyde dehydrogenase family
AS891_20055	COG0531	amino acid
AS891_20060	COG1011	Hydrolase
AS891_20065	COG2223	nitrite transmembrane transporter activity
AS891_20070	COG1442	glycosyl transferase family 8
AS891_20075	COG1216	Glycosyl transferase, family 2
AS891_20080	COG1442	glycosyl transferase family 8
AS891_20085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS891_20090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS891_20095	COG1368	sulfuric ester hydrolase activity
AS891_20100	COG2124	cytochrome p450
AS891_20100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS891_20110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS891_20115	COG1846	Transcriptional regulator
AS891_20120	COG0697	spore germination
AS891_20125	COG0670	Belongs to the BI1 family
AS891_20130	COG5583	Uncharacterized small protein (DUF2292)
AS891_20145	COG0346	lactoylglutathione lyase activity
AS891_20150	COG2329	Antibiotic biosynthesis monooxygenase
AS891_20155	COG2323	membrane
AS891_20160	COG1486	melibiose metabolic process
AS891_20165	COG0395	ABC-type sugar transport system, permease component
AS891_20170	COG4209	transmembrane transport
AS891_20175	COG1653	transport
AS891_20185	COG1874	Beta-galactosidase
AS891_20190	COG2755	lipolytic protein G-D-S-L family
AS891_20195	COG3401	FG-GAP repeat protein
AS891_20200	COG3401	FG-GAP repeat protein
AS891_20205	COG5578	integral membrane protein
AS891_20215	COG2755	lipolytic protein G-D-S-L family
AS891_20220	COG2207	Transcriptional regulator
AS891_20225	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AS891_20230	COG0395	ABC-type sugar transport system, permease component
AS891_20235	COG1175	transmembrane transport
AS891_20240	COG1653	transport
AS891_20245	COG2207	Transcriptional regulator
AS891_20245	COG4753	response regulator
AS891_20250	COG2972	Histidine kinase
AS891_20255	COG5578	integral membrane protein
AS891_20265	COG0454	-acetyltransferase
AS891_20270	COG3546	catalase activity
AS891_20285	COG0702	epimerase
AS891_20290	COG3631	Ketosteroid isomerase-related protein
AS891_20295	COG1309	transcriptional regulator
AS891_20305	COG0217	transcriptional regulatory protein
AS891_20315	COG0457	Tetratricopeptide repeat
AS891_20320	COG3391	amine dehydrogenase activity
AS891_20325	COG5444	nuclease activity
AS891_20345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS891_20350	COG1061	Type III restriction enzyme res subunit
AS891_20355	COG1002	Type II restriction enzyme, methylase subunits
AS891_20360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_20365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS891_20370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS891_20375	COG1597	lipid kinase activity
AS891_20380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS891_20385	COG1309	transcriptional regulator
AS891_20390	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS891_20395	COG0154	amidase activity
AS891_20400	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AS891_20405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS891_20410	COG1285	pathogenesis
AS891_20415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS891_20420	COG4851	CamS sex pheromone cAM373 precursor
AS891_20425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AS891_20430	COG0210	DNA helicase
AS891_20435	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AS891_20445	COG0069	glutamate synthase activity
AS891_20450	COG4496	protein, YerC YecD
AS891_20455	COG1470	cell adhesion involved in biofilm formation
AS891_20460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AS891_20470	COG0531	amino acid
AS891_20475	COG1522	sequence-specific DNA binding
AS891_20480	COG0151	Belongs to the GarS family
AS891_20485	COG0138	bifunctional purine biosynthesis protein purh
AS891_20490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AS891_20495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AS891_20500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AS891_20505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS891_20510	COG0047	phosphoribosylformylglycinamidine synthase activity
AS891_20515	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS891_20520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AS891_20525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS891_20530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AS891_20535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS891_20545	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AS891_20555	COG3064	Membrane
AS891_20560	COG2252	PERMEase
AS891_20565	COG0519	Catalyzes the synthesis of GMP from XMP
AS891_20565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AS891_20570	COG1305	Transglutaminase-like
AS891_20575	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AS891_20580	COG0714	Associated with various cellular activities
AS891_20585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS891_20595	COG1113	amino acid transport
AS891_20600	COG2132	Multicopper oxidase
AS891_20610	COG2267	carboxylic ester hydrolase activity
AS891_20625	COG0823	Involved in the tonB-independent uptake of proteins
AS891_20630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AS891_20635	COG1063	alcohol dehydrogenase
AS891_20640	COG2814	Major facilitator Superfamily
AS891_20650	COG4260	virion core protein, lumpy skin disease virus
AS891_20655	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AS891_20660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS891_20665	COG1842	Phage shock protein A
AS891_20670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS891_20675	COG2211	Major facilitator Superfamily
AS891_20680	COG1063	alcohol dehydrogenase
AS891_20685	COG0457	Tetratricopeptide repeat
AS891_20705	COG1401	restriction endodeoxyribonuclease activity
AS891_20725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS891_20730	COG0270	DNA (cytosine-5-)-methyltransferase activity
AS891_20735	COG0270	DNA (cytosine-5-)-methyltransferase activity
AS891_20750	COG3378	Phage plasmid primase P4 family
AS891_20765	COG0459	protein refolding
AS891_20770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AS891_20775	COG1266	CAAX protease self-immunity
AS891_20785	COG0805	protein transport
AS891_20790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS891_20795	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AS891_20800	COG0315	cyclic pyranopterin monophosphate synthase activity
AS891_20805	COG0488	(ABC) transporter
AS891_20810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AS891_20815	COG0456	acetyltransferase
AS891_20820	COG1214	PFAM Peptidase M22, glycoprotease
AS891_20825	COG0802	atpase or kinase
AS891_20830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AS891_20875	COG4124	Belongs to the glycosyl hydrolase 26 family
AS891_20880	COG1482	cell wall glycoprotein biosynthetic process
AS891_20885	COG1940	carbohydrate kinase activity
AS891_20890	COG2188	Transcriptional regulator
AS891_20895	COG2723	6-phospho-beta-galactosidase activity
AS891_20900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_20905	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS891_20910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS891_20915	COG2814	Major facilitator Superfamily
AS891_20920	COG1388	LysM domain
AS891_20925	COG1078	dGTPase activity
AS891_20930	COG0454	-acetyltransferase
AS891_20940	COG5646	InterPro IPR014922
AS891_20945	COG1785	Belongs to the alkaline phosphatase family
AS891_20955	COG1819	glycosyl
AS891_20960	COG3858	chitin binding
AS891_20960	COG1388	LysM domain
AS891_20965	COG1802	Transcriptional regulator
AS891_20970	COG0730	response to heat
AS891_20975	COG2814	Major facilitator Superfamily
AS891_20980	COG1846	Transcriptional regulator
AS891_20985	COG0778	Nitroreductase
AS891_20990	COG2409	Drug exporters of the RND superfamily
AS891_20990	COG1033	growth of symbiont in host cell
AS891_20995	COG1846	Transcriptional regulator
AS891_21000	COG2318	DinB family
AS891_21005	COG1113	amino acid transport
AS891_21015	COG0456	acetyltransferase
AS891_21025	COG1309	transcriptional regulator
AS891_21040	COG0071	Belongs to the small heat shock protein (HSP20) family
AS891_21045	COG2323	membrane
AS891_21050	COG2323	membrane
AS891_21070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_21075	COG2259	Doxx family
AS891_21080	COG0346	lactoylglutathione lyase activity
AS891_21085	COG0778	Nitroreductase
AS891_21090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS891_21095	COG4978	Transcriptional regulator
AS891_21095	COG0789	Transcriptional regulator
AS891_21100	COG1811	Na channel or pump
AS891_21105	COG0596	Alpha beta hydrolase
AS891_21110	COG2409	Drug exporters of the RND superfamily
AS891_21115	COG2197	response regulator
AS891_21120	COG4585	Histidine kinase
AS891_21130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS891_21135	COG0640	Transcriptional regulator
AS891_21140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS891_21145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_21150	COG0697	spore germination
AS891_21155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_21165	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS891_21170	COG0640	Transcriptional regulator
AS891_21180	COG1309	transcriptional regulator
AS891_21185	COG2814	Major facilitator Superfamily
AS891_21190	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS891_21195	COG1733	regulation of RNA biosynthetic process
AS891_21200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS891_21205	COG1733	regulation of RNA biosynthetic process
AS891_21210	COG3545	Serine hydrolase
AS891_21215	COG2030	dehydratase
AS891_21220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_21225	COG0697	spore germination
AS891_21235	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AS891_21245	COG0477	Major facilitator Superfamily
AS891_21250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_21255	COG2207	Transcriptional regulator
AS891_21255	COG3708	Transcriptional regulator
AS891_21260	COG0697	spore germination
AS891_21265	COG1917	Cupin 2, conserved barrel domain protein
AS891_21265	COG2207	Transcriptional regulator
AS891_21270	COG0697	spore germination
AS891_21275	COG1329	Transcriptional regulator
AS891_21280	COG1278	Cold shock
AS891_21285	COG0693	protein deglycase activity
AS891_21305	COG2814	Major facilitator Superfamily
AS891_21310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AS891_21315	COG1335	isochorismatase
AS891_21320	COG1522	sequence-specific DNA binding
AS891_21325	COG1522	sequence-specific DNA binding
AS891_21330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS891_21340	COG0457	Tetratricopeptide repeat
AS891_21360	COG0741	lytic transglycosylase activity
AS891_21360	COG0791	NLP P60 protein
AS891_21365	COG5644	endopeptidase inhibitor activity
AS891_21375	COG0433	COG0433 Predicted ATPase
AS891_21410	COG2946	Replication initiation factor
AS891_21415	COG1674	ftsk spoiiie
AS891_21440	COG1396	sequence-specific DNA binding
AS891_21445	COG2856	Zn peptidase
AS891_21450	COG0582	viral genome integration into host DNA
AS891_21490	COG3091	SprT-like family
AS891_21500	COG2183	response to ionizing radiation
AS891_21505	COG1846	Transcriptional regulator
AS891_21510	COG1673	EVE domain
AS891_21525	COG2208	phosphoserine phosphatase activity
AS891_21530	COG1191	sigma factor activity
AS891_21535	COG2172	sigma factor antagonist activity
AS891_21540	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_21545	COG2208	phosphoserine phosphatase activity
AS891_21550	COG2172	sigma factor antagonist activity
AS891_21555	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_21560	COG1366	Belongs to the anti-sigma-factor antagonist family
AS891_21565	COG2337	Toxic component of a toxin-antitoxin (TA) module
AS891_21570	COG0864	Transcriptional regulator
AS891_21575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS891_21580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AS891_21585	COG0736	holo-[acyl-carrier-protein] synthase activity
AS891_21590	COG0705	Rhomboid family
AS891_21595	COG3428	Bacterial PH domain
AS891_21600	COG3402	PFAM membrane-flanked domain
AS891_21605	COG0513	Belongs to the DEAD box helicase family
AS891_21610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS891_21615	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS891_21620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS891_21625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS891_21640	COG1960	acyl-CoA dehydrogenase activity
AS891_21650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS891_21655	COG1131	(ABC) transporter
AS891_21665	COG0628	permease
AS891_21670	COG1301	dicarboxylic acid transport
AS891_21675	COG4565	transcriptional regulatory protein
AS891_21680	COG3290	protein histidine kinase activity
AS891_21685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AS891_21690	COG3546	catalase activity
AS891_21695	COG2329	Antibiotic biosynthesis monooxygenase
AS891_21700	COG0662	Cupin 2, conserved barrel domain protein
AS891_21705	COG3729	General stress protein
AS891_21710	COG2217	Heavy metal translocating P-type atpase
AS891_21715	COG4876	unkown
AS891_21720	COG2261	transglycosylase associated protein
AS891_21725	COG1914	H( )-stimulated, divalent metal cation uptake system
AS891_21740	COG0028	Belongs to the TPP enzyme family
AS891_21745	COG0494	nUDIX hydrolase
AS891_21750	COG0531	amino acid
AS891_21760	COG1215	transferase activity, transferring glycosyl groups
AS891_21765	COG5298	Protein conserved in bacteria
AS891_21770	COG3706	GGDEF domain
AS891_21775	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AS891_21780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS891_21780	COG0551	DNA topoisomerase type I activity
AS891_21785	COG1522	sequence-specific DNA binding
AS891_21790	COG2814	Major facilitator Superfamily
AS891_21800	COG3871	stress protein (general stress protein 26)
AS891_21805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS891_21810	COG1917	Cupin 2, conserved barrel domain protein
AS891_21815	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_21820	COG2226	methyltransferase
AS891_21825	COG0318	PFAM AMP-dependent synthetase and ligase
AS891_21830	COG3711	transcriptional antiterminator
AS891_21835	COG4989	oxidoreductase activity
AS891_21840	COG0768	penicillin binding
AS891_21845	COG2329	Antibiotic biosynthesis monooxygenase
AS891_21855	COG2755	lipolytic protein G-D-S-L family
AS891_21860	COG1414	Transcriptional regulator
AS891_21865	COG1984	allophanate hydrolase subunit 2
AS891_21870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS891_21875	COG4336	lyase activity
AS891_21880	COG1914	H( )-stimulated, divalent metal cation uptake system
AS891_21885	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AS891_21890	COG0561	phosphatase activity
AS891_21900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS891_21905	COG0412	Dienelactone hydrolase
AS891_21915	COG0681	Belongs to the peptidase S26 family
AS891_21920	COG0473	3-isopropylmalate dehydrogenase activity
AS891_21925	COG0246	Mannitol dehydrogenase
AS891_21930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS891_21935	COG2213	PTS system mannitol-specific
AS891_21945	COG1349	DNA-binding transcription factor activity
AS891_21950	COG2372	response to copper ion
AS891_21950	COG1276	copper resistance
AS891_21955	COG4549	nuclear export factor GLE1
AS891_21960	COG1028	Short-chain dehydrogenase reductase Sdr
AS891_21965	COG4975	Glucose uptake
AS891_21970	COG1012	belongs to the aldehyde dehydrogenase family
AS891_21975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS891_21980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_21985	COG0640	Transcriptional regulator
AS891_21990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AS891_21995	COG0778	Nitroreductase
AS891_22000	COG1309	transcriptional regulator
AS891_22005	COG2814	Major facilitator Superfamily
AS891_22010	COG4607	ABC-type enterochelin transport system periplasmic component
AS891_22015	COG4604	ABC transporter, ATP-binding protein
AS891_22020	COG4605	iron ion homeostasis
AS891_22025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS891_22030	COG0527	aspartate kinase activity
AS891_22045	COG0457	Tetratricopeptide repeat
AS891_22050	COG3850	Histidine kinase
AS891_22050	COG5002	protein histidine kinase activity
AS891_22055	COG0745	RESPONSE REGULATOR receiver
AS891_22060	COG0577	efflux transmembrane transporter activity
AS891_22065	COG1136	(ABC) transporter
AS891_22070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AS891_22080	COG0697	spore germination
AS891_22090	COG5434	Belongs to the glycosyl hydrolase 28 family
AS891_22095	COG3104	oligopeptide transport
AS891_22100	COG0596	Alpha beta hydrolase
AS891_22115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AS891_22120	COG0163	prenyltransferase activity
AS891_22125	COG0583	DNA-binding transcription factor activity
AS891_22130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS891_22135	COG0765	amino acid transport
AS891_22140	COG1126	abc transporter atp-binding protein
AS891_22145	COG2364	Membrane
AS891_22155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS891_22160	COG0697	spore germination
AS891_22170	COG2814	Major facilitator Superfamily
AS891_22175	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AS891_22180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity