locus-tag	class	description
D9C17_00005	COG3953	SLT domain
D9C17_00005	COG5412	phage tail tape measure protein
D9C17_00105	COG4282	regulation of fungal-type cell wall biogenesis
D9C17_00130	COG3328	transposase activity
D9C17_00145	COG3655	Transcriptional regulator
D9C17_00170	COG0135	phosphoribosylanthranilate isomerase activity
D9C17_00175	COG2211	Major facilitator Superfamily
D9C17_00190	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C17_00195	COG1940	carbohydrate kinase activity
D9C17_00200	COG2115	Belongs to the xylose isomerase family
D9C17_00205	COG1070	Carbohydrate kinase
D9C17_00220	COG3328	transposase activity
D9C17_00225	COG1525	nuclease
D9C17_00230	COG2814	Major facilitator Superfamily
D9C17_00235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C17_00250	COG0756	dUTP diphosphatase activity
D9C17_00295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C17_00310	COG3832	glyoxalase III activity
D9C17_00355	COG4195	phage-related replication protein
D9C17_00365	COG0346	lactoylglutathione lyase activity
D9C17_00375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9C17_00380	COG1388	LysM domain
D9C17_00385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C17_00390	COG4224	UPF0291 protein
D9C17_00395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9C17_00405	COG3763	UPF0154 protein
D9C17_00415	COG0785	Cytochrome C biogenesis protein
D9C17_00420	COG2201	protein-glutamate methylesterase activity
D9C17_00425	COG4846	Membrane protein involved in cytochrome C biogenesis
D9C17_00435	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C17_00450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9C17_00455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_00475	COG0824	Thioesterase
D9C17_00485	COG4841	protein insertion into membrane
D9C17_00490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9C17_00495	COG1832	CoA-binding protein
D9C17_00500	COG0187	DNA topoisomerase II activity
D9C17_00505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C17_00515	COG1115	amino acid carrier protein
D9C17_00520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9C17_00530	COG5520	Belongs to the glycosyl hydrolase 30 family
D9C17_00540	COG2246	polysaccharide biosynthetic process
D9C17_00545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C17_00550	COG0586	Pfam SNARE associated Golgi protein
D9C17_00555	COG2404	hydrolase activity, acting on ester bonds
D9C17_00560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C17_00565	COG1024	Enoyl-CoA hydratase
D9C17_00570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C17_00575	COG0511	ligase activity, forming carbon-carbon bonds
D9C17_00580	COG0439	Biotin carboxylase
D9C17_00585	COG0318	PFAM AMP-dependent synthetase and ligase
D9C17_00590	COG1960	acyl-CoA dehydrogenase activity
D9C17_00600	COG1649	PFAM Uncharacterised BCR, COG1649
D9C17_00615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C17_00620	COG2027	D-alanyl-D-alanine carboxypeptidase
D9C17_00625	COG2017	converts alpha-aldose to the beta-anomer
D9C17_00630	COG0534	Mate efflux family protein
D9C17_00650	COG0582	viral genome integration into host DNA
D9C17_00655	COG0166	Belongs to the GPI family
D9C17_00660	COG0405	Gamma-glutamyltransferase
D9C17_00665	COG0583	DNA-binding transcription factor activity
D9C17_00670	COG0604	alcohol dehydrogenase
D9C17_00675	COG0493	'glutamate synthase
D9C17_00680	COG0067	glutamate synthase
D9C17_00680	COG0069	glutamate synthase activity
D9C17_00680	COG0070	glutamate synthase
D9C17_00685	COG0583	DNA-binding transcription factor activity
D9C17_00715	COG0300	oxidoreductase activity
D9C17_00720	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C17_00730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_00745	COG1131	(ABC) transporter
D9C17_00755	COG2814	Major facilitator Superfamily
D9C17_00765	COG3328	transposase activity
D9C17_00805	COG3328	transposase activity
D9C17_00865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C17_00870	COG2226	methyltransferase
D9C17_00875	COG2211	Major facilitator Superfamily
D9C17_00880	COG3328	transposase activity
D9C17_00910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_00930	COG5444	nuclease activity
D9C17_00935	COG4282	regulation of fungal-type cell wall biogenesis
D9C17_00940	COG1231	oxidoreductase activity
D9C17_00945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C17_00950	COG2207	Transcriptional regulator
D9C17_00950	COG0662	Cupin 2, conserved barrel domain protein
D9C17_00955	COG0456	acetyltransferase
D9C17_00960	COG1309	transcriptional regulator
D9C17_00965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C17_00970	COG3708	Transcriptional regulator
D9C17_00975	COG2378	regulation of single-species biofilm formation
D9C17_00985	COG0640	Transcriptional regulator
D9C17_00990	COG0741	lytic transglycosylase activity
D9C17_00995	COG2322	membrane
D9C17_01010	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C17_01015	COG3239	Fatty acid desaturase
D9C17_01020	COG4585	Histidine kinase
D9C17_01025	COG2197	response regulator
D9C17_01030	COG3584	3D domain protein
D9C17_01030	COG1388	LysM domain
D9C17_01035	COG0514	ATP-dependent DNA helicase (RecQ)
D9C17_01050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C17_01055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C17_01070	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C17_01095	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_01100	COG1657	PFAM Prenyltransferase squalene oxidase
D9C17_01105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C17_01110	COG0733	neurotransmitter:sodium symporter activity
D9C17_01115	COG0385	Bile acid
D9C17_01120	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C17_01125	COG0567	Dehydrogenase, E1 component
D9C17_01130	COG4548	von Willebrand factor, type A
D9C17_01135	COG0714	Associated with various cellular activities
D9C17_01140	COG2032	superoxide dismutase activity
D9C17_01145	COG1388	LysM domain
D9C17_01145	COG0791	NLP P60 protein
D9C17_01150	COG1819	glycosyl
D9C17_01155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C17_01160	COG0534	Mate efflux family protein
D9C17_01165	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_01170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C17_01175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C17_01185	COG2962	Rard protein
D9C17_01205	COG1942	4-Oxalocrotonate Tautomerase
D9C17_01210	COG1733	regulation of RNA biosynthetic process
D9C17_01215	COG0778	Nitroreductase
D9C17_01225	COG0400	carboxylic ester hydrolase activity
D9C17_01240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C17_01245	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_01245	COG0793	Belongs to the peptidase S41A family
D9C17_01250	COG2226	methyltransferase
D9C17_01260	COG1876	peptidase activity
D9C17_01265	COG0813	purine-nucleoside phosphorylase activity
D9C17_01280	COG0671	phosphoesterase, PA-phosphatase related
D9C17_01305	COG4479	Belongs to the UPF0346 family
D9C17_01315	COG1509	lysine 2,3-aminomutase activity
D9C17_01320	COG0456	acetyltransferase
D9C17_01325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C17_01330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C17_01335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C17_01340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C17_01355	COG0456	acetyltransferase
D9C17_01360	COG0463	Glycosyl transferase, family 2
D9C17_01375	COG4641	Protein conserved in bacteria
D9C17_01380	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D9C17_01385	COG1086	Polysaccharide biosynthesis protein
D9C17_01390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C17_01395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C17_01400	COG1846	Transcriptional regulator
D9C17_01405	COG0534	Mate efflux family protein
D9C17_01415	COG4698	Protein conserved in bacteria
D9C17_01420	COG2755	lipolytic protein G-D-S-L family
D9C17_01425	COG1999	signal sequence binding
D9C17_01435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9C17_01440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C17_01445	COG1272	protein, Hemolysin III
D9C17_01450	COG0204	Acyl-transferase
D9C17_01455	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C17_01460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C17_01470	COG2136	Putative SAM-dependent methyltransferase
D9C17_01470	COG2521	methyltransferase
D9C17_01480	COG0129	dihydroxy-acid dehydratase activity
D9C17_01485	COG1413	lyase activity
D9C17_01490	COG1418	mRNA catabolic process
D9C17_01495	COG0386	Belongs to the glutathione peroxidase family
D9C17_01500	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9C17_01505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C17_01515	COG1278	Cold shock
D9C17_01535	COG0328	RNA-DNA hybrid ribonuclease activity
D9C17_01540	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9C17_01545	COG0328	RNA-DNA hybrid ribonuclease activity
D9C17_01555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C17_01570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C17_01580	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9C17_01585	COG3424	synthase
D9C17_01590	COG2233	PERMEase
D9C17_01595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C17_01600	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9C17_01610	COG0800	Aldolase
D9C17_01615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C17_01620	COG1609	Transcriptional regulator
D9C17_01625	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9C17_01630	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_01635	COG1199	ATP-dependent helicase activity
D9C17_01650	COG0116	Belongs to the methyltransferase superfamily
D9C17_01665	COG4474	Belongs to the UPF0398 family
D9C17_01680	COG3359	exonuclease
D9C17_01685	COG1111	helicase
D9C17_01685	COG1205	dead DEAH box helicase
D9C17_01690	COG2190	(PTS) system
D9C17_01695	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C17_01730	COG3331	DNA recombination
D9C17_01735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C17_01735	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C17_01745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9C17_01750	COG3935	DnaD domain protein
D9C17_01755	COG0017	Asparaginyl-tRNA synthetase
D9C17_01760	COG0436	Aminotransferase
D9C17_01765	COG5353	protein conserved in bacteria
D9C17_01775	COG1199	ATP-dependent helicase activity
D9C17_01775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9C17_01780	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9C17_01785	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9C17_01790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9C17_01795	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D9C17_01795	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D9C17_01800	COG0617	tRNA 3'-terminal CCA addition
D9C17_01805	COG0438	transferase activity, transferring glycosyl groups
D9C17_01810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C17_01815	COG1803	Methylglyoxal synthase
D9C17_01820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9C17_01825	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C17_01830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C17_01840	COG4347	Protein of unknown function (DUF1405)
D9C17_01845	COG2010	Cytochrome c
D9C17_01845	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C17_01850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C17_01855	COG0723	plastoquinol--plastocyanin reductase activity
D9C17_01865	COG5582	Belongs to the UPF0302 family
D9C17_01870	COG0457	Tetratricopeptide repeat
D9C17_01875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9C17_01880	COG0287	Prephenate dehydrogenase
D9C17_01895	COG0133	tryptophan synthase activity
D9C17_01900	COG0135	phosphoribosylanthranilate isomerase activity
D9C17_01910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9C17_01915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C17_01920	COG4401	Chorismate mutase type I
D9C17_01925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9C17_01930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9C17_01935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9C17_01940	COG0105	UTP biosynthetic process
D9C17_01945	COG0142	geranyltranstransferase activity
D9C17_01950	COG2226	methyltransferase
D9C17_01955	COG0142	geranyltranstransferase activity
D9C17_01965	COG0302	gtp cyclohydrolase
D9C17_01970	COG0776	regulation of translation
D9C17_01975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C17_01990	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9C17_01995	COG1160	GTP binding
D9C17_02020	COG1304	FMN binding
D9C17_02025	COG0539	negative regulation of cytoplasmic translation
D9C17_02030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9C17_02040	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9C17_02045	COG2959	enzyme of heme biosynthesis
D9C17_02050	COG3773	Cell wall hydrolase
D9C17_02050	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_02055	COG2339	peptidase activity
D9C17_02060	COG0492	ferredoxin-NADP+ reductase activity
D9C17_02065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C17_02070	COG4862	establishment of competence for transformation
D9C17_02075	COG1408	metallophosphoesterase
D9C17_02085	COG1388	LysM domain
D9C17_02090	COG1266	CAAX protease self-immunity
D9C17_02095	COG0514	ATP-dependent DNA helicase (RecQ)
D9C17_02100	COG4955	Helix-turn-helix domain
D9C17_02105	COG1141	Ferredoxin
D9C17_02110	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9C17_02115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C17_02120	COG0710	3-dehydroquinate dehydratase activity
D9C17_02130	COG1595	DNA-templated transcription, initiation
D9C17_02135	COG5002	protein histidine kinase activity
D9C17_02140	COG0745	RESPONSE REGULATOR receiver
D9C17_02145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C17_02150	COG1333	cytochrome c biogenesis protein
D9C17_02155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_02160	COG1187	pseudouridine synthase activity
D9C17_02165	COG0700	Nucleoside recognition
D9C17_02170	COG2715	membrane protein required for spore maturation
D9C17_02175	COG1686	Belongs to the peptidase S11 family
D9C17_02185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9C17_02190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9C17_02195	COG1547	Domain of unknown function (DUF309)
D9C17_02200	COG0456	acetyltransferase
D9C17_02205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9C17_02210	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C17_02210	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C17_02215	COG0307	riboflavin synthase, alpha
D9C17_02220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C17_02220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C17_02230	COG0681	Belongs to the peptidase S26 family
D9C17_02240	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9C17_02290	COG3328	transposase activity
D9C17_02345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9C17_02360	COG4086	secreted protein
D9C17_02365	COG0019	diaminopimelate decarboxylase activity
D9C17_02370	COG0697	spore germination
D9C17_02385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C17_02405	COG1191	sigma factor activity
D9C17_02410	COG2172	sigma factor antagonist activity
D9C17_02415	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_02420	COG1686	Belongs to the peptidase S11 family
D9C17_02425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9C17_02430	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9C17_02435	COG4974	Belongs to the 'phage' integrase family
D9C17_02445	COG0735	belongs to the Fur family
D9C17_02450	COG1300	Membrane
D9C17_02460	COG0281	malic enzyme
D9C17_02465	COG1757	Na H antiporter
D9C17_02470	COG1027	Aspartate ammonia-lyase
D9C17_02475	COG0252	asparaginase activity
D9C17_02480	COG1396	sequence-specific DNA binding
D9C17_02485	COG1379	DNA repair
D9C17_02490	COG0494	nUDIX hydrolase
D9C17_02500	COG0667	Aldo Keto reductase
D9C17_02510	COG1073	alpha beta
D9C17_02520	COG4918	Iron-sulphur cluster biosynthesis
D9C17_02525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9C17_02525	COG0456	acetyltransferase
D9C17_02530	COG2329	Antibiotic biosynthesis monooxygenase
D9C17_02535	COG0456	acetyltransferase
D9C17_02545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C17_02555	COG2211	Major facilitator Superfamily
D9C17_02560	COG0346	lactoylglutathione lyase activity
D9C17_02565	COG1072	(Pantothenic acid kinase))
D9C17_02570	COG3048	D-serine ammonia-lyase activity
D9C17_02575	COG0300	oxidoreductase activity
D9C17_02580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C17_02585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C17_02590	COG4187	Peptidase family M20/M25/M40
D9C17_02595	COG1902	pentaerythritol trinitrate reductase activity
D9C17_02610	COG0596	Alpha beta hydrolase
D9C17_02620	COG1234	tRNA 3'-trailer cleavage
D9C17_02625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9C17_02630	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C17_02635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C17_02645	COG0706	membrane insertase activity
D9C17_02650	COG3361	conserved protein (COG2071)
D9C17_02655	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C17_02665	COG0346	lactoylglutathione lyase activity
D9C17_02670	COG1376	ErfK ybiS ycfS ynhG family protein
D9C17_02675	COG4129	membrane
D9C17_02680	COG1126	abc transporter atp-binding protein
D9C17_02685	COG0765	amino acid transport
D9C17_02690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C17_02700	COG1597	lipid kinase activity
D9C17_02710	COG4978	Transcriptional regulator
D9C17_02710	COG0789	Transcriptional regulator
D9C17_02715	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C17_02720	COG0022	dehydrogenase e1 component
D9C17_02725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C17_02730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C17_02735	COG3426	butyrate kinase activity
D9C17_02740	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C17_02745	COG0280	phosphate acetyltransferase
D9C17_02750	COG3290	protein histidine kinase activity
D9C17_02750	COG3829	transcription factor binding
D9C17_02760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9C17_02765	COG2079	MmgE PrpD family protein
D9C17_02770	COG0372	Belongs to the citrate synthase family
D9C17_02775	COG1960	acyl-CoA dehydrogenase activity
D9C17_02780	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C17_02785	COG0183	Belongs to the thiolase family
D9C17_02790	COG0584	glycerophosphoryl diester phosphodiesterase
D9C17_02795	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C17_02810	COG1902	pentaerythritol trinitrate reductase activity
D9C17_02815	COG0745	RESPONSE REGULATOR receiver
D9C17_02825	COG0750	zinc metalloprotease
D9C17_02830	COG0497	DNA recombination
D9C17_02835	COG1438	arginine binding
D9C17_02840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9C17_02845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9C17_02850	COG0142	geranyltranstransferase activity
D9C17_02855	COG1722	exodeoxyribonuclease VII activity
D9C17_02860	COG1570	exodeoxyribonuclease VII activity
D9C17_02865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9C17_02870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C17_02875	COG1302	Protein conserved in bacteria
D9C17_02880	COG0439	Biotin carboxylase
D9C17_02885	COG0511	ligase activity, forming carbon-carbon bonds
D9C17_02930	COG3854	ATPases associated with a variety of cellular activities
D9C17_02940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9C17_02945	COG0006	proline dipeptidase activity
D9C17_02950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9C17_02960	COG3872	metal-dependent enzyme
D9C17_02970	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C17_02975	COG1321	iron dependent repressor
D9C17_02980	COG0095	Lipoate-protein ligase
D9C17_02985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C17_02990	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C17_02995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C17_03000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9C17_03005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C17_03020	COG1396	sequence-specific DNA binding
D9C17_03030	COG0681	Belongs to the peptidase S26 family
D9C17_03055	COG4940	Competence protein ComGF
D9C17_03065	COG4970	Tfp pilus assembly protein FimT
D9C17_03070	COG4537	Required for transformation and DNA binding
D9C17_03075	COG1459	type II secretion system
D9C17_03080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9C17_03085	COG0517	IMP dehydrogenase activity
D9C17_03090	COG0598	Magnesium transport protein CorA
D9C17_03095	COG1253	flavin adenine dinucleotide binding
D9C17_03100	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_03110	COG1393	Belongs to the ArsC family
D9C17_03120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C17_03130	COG0011	TIGRFAM Protein of
D9C17_03140	COG2866	Carboxypeptidase
D9C17_03145	COG1368	sulfuric ester hydrolase activity
D9C17_03150	COG1940	carbohydrate kinase activity
D9C17_03155	COG4483	Protein conserved in bacteria
D9C17_03160	COG0705	Rhomboid family
D9C17_03160	COG0457	Tetratricopeptide repeat
D9C17_03170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9C17_03175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C17_03180	COG0438	transferase activity, transferring glycosyl groups
D9C17_03195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C17_03200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C17_03205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C17_03210	COG0581	inorganic phosphate transmembrane transporter activity
D9C17_03215	COG0573	inorganic phosphate transmembrane transporter activity
D9C17_03220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9C17_03230	COG0477	Major facilitator Superfamily
D9C17_03235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C17_03240	COG2839	Protein conserved in bacteria
D9C17_03245	COG5521	maltodextrose utilization protein MalA
D9C17_03250	COG1388	LysM domain
D9C17_03255	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9C17_03260	COG4709	membrane
D9C17_03265	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9C17_03270	COG0735	belongs to the Fur family
D9C17_03275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C17_03285	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9C17_03290	COG0513	Belongs to the DEAD box helicase family
D9C17_03300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9C17_03305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9C17_03310	COG2384	SAM-dependent methyltransferase
D9C17_03315	COG2010	Cytochrome c
D9C17_03325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9C17_03330	COG0358	DNA primase activity
D9C17_03335	COG1671	Belongs to the UPF0178 family
D9C17_03340	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9C17_03345	COG0517	IMP dehydrogenase activity
D9C17_03350	COG0751	glycine-tRNA ligase activity
D9C17_03355	COG0752	glycyl-tRNA synthetase alpha subunit
D9C17_03360	COG1381	Involved in DNA repair and RecF pathway recombination
D9C17_03370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9C17_03375	COG0295	cytidine deaminase activity
D9C17_03380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9C17_03385	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9C17_03390	COG1480	7TM receptor with intracellular HD hydrolase
D9C17_03395	COG1702	phosphate starvation-inducible protein PhoH
D9C17_03400	COG0561	phosphatase activity
D9C17_03415	COG4864	UPF0365 protein
D9C17_03420	COG1030	water channel activity
D9C17_03425	COG1610	YqeY-like protein
D9C17_03430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9C17_03435	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9C17_03440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C17_03445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9C17_03450	COG2264	protein methyltransferase activity
D9C17_03455	COG0484	heat shock protein binding
D9C17_03460	COG0443	Heat shock 70 kDa protein
D9C17_03465	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9C17_03470	COG1420	regulation of RNA biosynthetic process
D9C17_03475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C17_03480	COG0481	GTPase activity
D9C17_03490	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C17_03495	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9C17_03500	COG0268	Binds directly to 16S ribosomal RNA
D9C17_03505	COG1466	dna polymerase III delta subunit
D9C17_03520	COG0658	competence protein
D9C17_03520	COG2333	competence protein COMEC
D9C17_03525	COG2131	deaminase
D9C17_03530	COG1596	polysaccharide export
D9C17_03530	COG1555	photosystem II stabilization
D9C17_03535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C17_03540	COG2226	methyltransferase
D9C17_03545	COG0799	negative regulation of ribosome biogenesis
D9C17_03550	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9C17_03555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9C17_03560	COG1534	Rna-binding protein
D9C17_03565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9C17_03570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C17_03575	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9C17_03585	COG2755	lipolytic protein G-D-S-L family
D9C17_03590	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_03590	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C17_03595	COG0398	Pfam SNARE associated Golgi protein
D9C17_03600	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D9C17_03610	COG3209	COG3209 Rhs family protein
D9C17_03630	COG0114	fumarate hydratase activity
D9C17_03635	COG0583	DNA-binding transcription factor activity
D9C17_03650	COG0457	Tetratricopeptide repeat
D9C17_03775	COG0789	Transcriptional regulator
D9C17_03775	COG4978	Transcriptional regulator
D9C17_03780	COG2814	Major facilitator Superfamily
D9C17_03785	COG0456	acetyltransferase
D9C17_03790	COG1253	flavin adenine dinucleotide binding
D9C17_03800	COG0697	spore germination
D9C17_03805	COG0583	DNA-binding transcription factor activity
D9C17_03810	COG2072	flavoprotein involved in K transport
D9C17_03815	COG1230	cation diffusion facilitator family transporter
D9C17_03825	COG1114	Component of the transport system for branched-chain amino acids
D9C17_03830	COG1687	branched-chain amino acid
D9C17_03840	COG1522	sequence-specific DNA binding
D9C17_03845	COG2732	(Barnase) inhibitor
D9C17_03850	COG2124	cytochrome p450
D9C17_03860	COG1335	isochorismatase
D9C17_03875	COG2318	DinB family
D9C17_03885	COG2070	2-Nitropropane dioxygenase
D9C17_03900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C17_03920	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9C17_03925	COG1595	DNA-templated transcription, initiation
D9C17_03930	COG0667	Aldo Keto reductase
D9C17_03935	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_03940	COG5566	PFAM Mor transcription activator
D9C17_03950	COG4991	sh3 domain protein
D9C17_03955	COG4991	sh3 domain protein
D9C17_03965	COG0346	lactoylglutathione lyase activity
D9C17_03975	COG5577	PFAM Coat F domain
D9C17_03980	COG1063	alcohol dehydrogenase
D9C17_03990	COG5577	PFAM Coat F domain
D9C17_03995	COG0789	Transcriptional regulator
D9C17_04005	COG1064	alcohol dehydrogenase
D9C17_04010	COG0693	protein deglycase activity
D9C17_04015	COG1621	beta-fructofuranosidase activity
D9C17_04020	COG3716	PTS system mannose fructose sorbose family IID component
D9C17_04025	COG3715	PTS system
D9C17_04030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_04035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_04040	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D9C17_04040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C17_04050	COG1113	amino acid transport
D9C17_04055	COG1280	lysine exporter protein (LysE YggA)
D9C17_04060	COG1378	Sugar-specific transcriptional regulator TrmB
D9C17_04065	COG1595	DNA-templated transcription, initiation
D9C17_04090	COG1309	transcriptional regulator
D9C17_04095	COG2226	methyltransferase
D9C17_04110	COG2116	formate transmembrane transporter activity
D9C17_04115	COG5609	conserved protein (DUF2294)
D9C17_04120	COG3383	formate dehydrogenase (NAD+) activity
D9C17_04125	COG2427	Protein of unknown function (DUF1641)
D9C17_04140	COG0626	cystathionine gamma-synthase activity
D9C17_04145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C17_04150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9C17_04155	COG2226	methyltransferase
D9C17_04170	COG0768	penicillin binding
D9C17_04175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9C17_04180	COG0572	uridine kinase
D9C17_04200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C17_04205	COG3906	Belongs to the UPF0473 family
D9C17_04210	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9C17_04215	COG4472	Bacterial protein of unknown function (DUF965)
D9C17_04220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9C17_04225	COG0628	permease
D9C17_04230	COG1126	abc transporter atp-binding protein
D9C17_04235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C17_04240	COG0765	amino acid transport
D9C17_04245	COG0765	amino acid transport
D9C17_04260	COG3881	PFAM PRC-barrel domain
D9C17_04265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9C17_04270	COG0457	Tetratricopeptide repeat
D9C17_04275	COG0482	sulfurtransferase activity
D9C17_04280	COG1104	cysteine desulfurase activity
D9C17_04285	COG1959	2 iron, 2 sulfur cluster binding
D9C17_04290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9C17_04295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9C17_04305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9C17_04310	COG0124	histidyl-tRNA synthetase
D9C17_04320	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C17_04320	COG3103	Sh3 type 3 domain protein
D9C17_04320	COG4991	sh3 domain protein
D9C17_04325	COG1490	D-aminoacyl-tRNA deacylase activity
D9C17_04330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9C17_04335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C17_04340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9C17_04340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9C17_04345	COG5416	Lipopolysaccharide assembly protein A domain
D9C17_04350	COG0490	domain, Protein
D9C17_04355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C17_04355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C17_04365	COG2244	polysaccharide biosynthetic process
D9C17_04370	COG2323	membrane
D9C17_04380	COG1862	Preprotein translocase
D9C17_04385	COG0343	queuine tRNA-ribosyltransferase activity
D9C17_04390	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9C17_04400	COG2255	four-way junction helicase activity
D9C17_04405	COG0632	four-way junction helicase activity
D9C17_04415	COG2814	Major facilitator Superfamily
D9C17_04420	COG0673	inositol 2-dehydrogenase activity
D9C17_04425	COG2112	serine threonine protein kinase
D9C17_04445	COG1115	amino acid carrier protein
D9C17_04450	COG0217	transcriptional regulatory protein
D9C17_04460	COG1388	LysM domain
D9C17_04465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9C17_04470	COG0157	Belongs to the NadC ModD family
D9C17_04475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9C17_04480	COG1104	cysteine desulfurase activity
D9C17_04485	COG1827	regulation of RNA biosynthetic process
D9C17_04490	COG0077	Prephenate dehydratase
D9C17_04495	COG4492	Belongs to the UPF0735 family
D9C17_04500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9C17_04505	COG3290	protein histidine kinase activity
D9C17_04515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9C17_04520	COG2868	ribosomal protein
D9C17_04525	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9C17_04530	COG1994	Peptidase M50
D9C17_04535	COG0739	heme binding
D9C17_04540	COG2894	cell division
D9C17_04545	COG0850	regulation of cytokinetic process
D9C17_04550	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9C17_04555	COG1792	Involved in formation and maintenance of cell shape
D9C17_04560	COG1077	Cell shape determining protein MreB Mrl
D9C17_04565	COG2003	Belongs to the UPF0758 family
D9C17_04570	COG0424	maF-like protein
D9C17_04580	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9C17_04585	COG0285	dihydrofolate synthase activity
D9C17_04590	COG0525	valine-tRNA ligase activity
D9C17_04600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C17_04605	COG1388	LysM domain
D9C17_04610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C17_04615	COG0113	porphobilinogen synthase activity
D9C17_04620	COG1587	Uroporphyrinogen-III synthase
D9C17_04625	COG0181	hydroxymethylbilane synthase activity
D9C17_04630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C17_04635	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9C17_04645	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9C17_04650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9C17_04655	COG0470	DNA polymerase III
D9C17_04655	COG1067	ATP-dependent peptidase activity
D9C17_04660	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9C17_04665	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9C17_04670	COG1477	protein flavinylation
D9C17_04670	COG0457	Tetratricopeptide repeat
D9C17_04675	COG0066	3-isopropylmalate dehydratase activity
D9C17_04680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9C17_04685	COG0473	3-isopropylmalate dehydrogenase activity
D9C17_04690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C17_04695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9C17_04700	COG0440	acetolactate synthase activity
D9C17_04705	COG0028	Belongs to the TPP enzyme family
D9C17_04725	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D9C17_04755	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
D9C17_04780	COG0622	Phosphoesterase
D9C17_04785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9C17_04790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9C17_04795	COG5401	PFAM Sporulation and spore germination
D9C17_04800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C17_04805	COG1846	Transcriptional regulator
D9C17_04810	COG2197	response regulator
D9C17_04815	COG0824	Thioesterase
D9C17_04820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9C17_04825	COG1053	succinate dehydrogenase
D9C17_04830	COG2009	succinate dehydrogenase
D9C17_04835	COG1719	4-vinyl reductase, 4VR
D9C17_04840	COG0527	aspartate kinase activity
D9C17_04850	COG0322	excinuclease ABC activity
D9C17_04855	COG3118	belongs to the thioredoxin family
D9C17_04860	COG3534	alpha-L-arabinofuranosidase
D9C17_04865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9C17_04870	COG2086	electron transfer activity
D9C17_04875	COG1024	Enoyl-CoA hydratase
D9C17_04880	COG1309	transcriptional regulator
D9C17_04885	COG0318	PFAM AMP-dependent synthetase and ligase
D9C17_04890	COG3766	membrane
D9C17_04895	COG1193	negative regulation of DNA recombination
D9C17_04900	COG1796	DNA polymerase
D9C17_04900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C17_04905	COG1286	toxin biosynthetic process
D9C17_04910	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9C17_04915	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C17_04920	COG0072	phenylalanine-tRNA ligase activity
D9C17_04920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C17_04925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9C17_04935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C17_04945	COG3835	regulator
D9C17_04950	COG0277	FAD linked oxidase domain protein
D9C17_04955	COG0247	lactate metabolic process
D9C17_04960	COG0346	lactoylglutathione lyase activity
D9C17_04965	COG1966	Carbon starvation protein
D9C17_04970	COG3534	alpha-L-arabinofuranosidase
D9C17_04975	COG0395	ABC-type sugar transport system, permease component
D9C17_04980	COG1175	transmembrane transport
D9C17_04985	COG1653	transport
D9C17_04990	COG0371	Dehydrogenase
D9C17_04995	COG0647	UMP catabolic process
D9C17_05000	COG0235	Class ii aldolase
D9C17_05005	COG1069	ribulokinase activity
D9C17_05010	COG2160	L-arabinose isomerase activity
D9C17_05020	COG1363	Peptidase, m42
D9C17_05030	COG3326	Membrane
D9C17_05035	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9C17_05040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9C17_05045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9C17_05055	COG1346	cytolysis
D9C17_05060	COG1380	Effector of murein hydrolase LrgA
D9C17_05065	COG3279	Response regulator of the LytR AlgR family
D9C17_05070	COG3275	phosphorelay sensor kinase activity
D9C17_05080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C17_05090	COG0398	Pfam SNARE associated Golgi protein
D9C17_05095	COG1484	DNA-dependent DNA replication
D9C17_05100	COG3611	Membrane attachment protein
D9C17_05105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9C17_05110	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9C17_05115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C17_05120	COG1733	regulation of RNA biosynthetic process
D9C17_05125	COG2814	Major facilitator Superfamily
D9C17_05130	COG0656	L-ascorbic acid biosynthetic process
D9C17_05135	COG0237	dephospho-CoA kinase activity
D9C17_05140	COG1971	Probably functions as a manganese efflux pump
D9C17_05145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9C17_05150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C17_05150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C17_05155	COG5002	protein histidine kinase activity
D9C17_05160	COG0745	RESPONSE REGULATOR receiver
D9C17_05165	COG0039	L-malate dehydrogenase activity
D9C17_05170	COG0538	isocitrate dehydrogenase activity
D9C17_05175	COG0372	Belongs to the citrate synthase family
D9C17_05180	COG2707	UPF0756 membrane protein
D9C17_05185	COG0628	permease
D9C17_05190	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9C17_05195	COG0469	pyruvate kinase activity
D9C17_05200	COG0205	6-phosphofructokinase activity
D9C17_05205	COG0825	malonyl-CoA metabolic process
D9C17_05210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9C17_05215	COG0281	malic enzyme
D9C17_05220	COG0587	DNA-directed DNA polymerase activity
D9C17_05240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9C17_05250	COG4109	DRTGG domain
D9C17_05260	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9C17_05265	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_05275	COG0165	Argininosuccinate lyase
D9C17_05280	COG0137	argininosuccinate synthase activity
D9C17_05285	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9C17_05290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9C17_05300	COG0827	DNA restriction-modification system
D9C17_05305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9C17_05310	COG3874	Sporulation protein YtfJ
D9C17_05320	COG1714	RDD family
D9C17_05325	COG0616	signal peptide processing
D9C17_05330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C17_05335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9C17_05340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C17_05350	COG0301	tRNA thio-modification
D9C17_05355	COG1104	cysteine desulfurase activity
D9C17_05360	COG1114	Component of the transport system for branched-chain amino acids
D9C17_05365	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9C17_05370	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C17_05375	COG1309	transcriptional regulator
D9C17_05380	COG1956	GAF domain-containing protein
D9C17_05385	COG2199	diguanylate cyclase activity
D9C17_05385	COG2203	Gaf domain
D9C17_05395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9C17_05400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C17_05405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C17_05410	COG0454	-acetyltransferase
D9C17_05415	COG0517	IMP dehydrogenase activity
D9C17_05420	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9C17_05425	COG1360	Flagellar Motor Protein
D9C17_05430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C17_05435	COG1609	Transcriptional regulator
D9C17_05440	COG1605	Chorismate mutase
D9C17_05440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9C17_05445	COG3118	belongs to the thioredoxin family
D9C17_05450	COG4980	gas vesicle protein
D9C17_05455	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C17_05460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9C17_05465	COG1674	ftsk spoiiie
D9C17_05470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C17_05475	COG4848	Belongs to the UPF0354 family
D9C17_05480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_05495	COG1363	Peptidase, m42
D9C17_05500	COG5584	Small secreted protein
D9C17_05505	COG0281	malic enzyme
D9C17_05510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C17_05515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9C17_05525	COG0510	thiamine kinase activity
D9C17_05530	COG1523	belongs to the glycosyl hydrolase 13 family
D9C17_05535	COG1597	lipid kinase activity
D9C17_05545	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C17_05550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C17_05555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C17_05560	COG2252	PERMEase
D9C17_05565	COG4473	ABC transporter
D9C17_05570	COG1131	(ABC) transporter
D9C17_05575	COG1349	DNA-binding transcription factor activity
D9C17_05580	COG1187	pseudouridine synthase activity
D9C17_05585	COG2244	polysaccharide biosynthetic process
D9C17_05590	COG2081	HI0933 family
D9C17_05595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9C17_05615	COG1653	transport
D9C17_05620	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C17_05625	COG4209	transmembrane transport
D9C17_05635	COG1653	transport
D9C17_05640	COG0395	ABC-type sugar transport system, permease component
D9C17_05645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C17_05650	COG2124	cytochrome p450
D9C17_05670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C17_05680	COG1073	alpha beta
D9C17_05705	COG1486	melibiose metabolic process
D9C17_05710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C17_05715	COG0495	leucyl-tRNA aminoacylation
D9C17_05725	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_05725	COG2202	Pas domain
D9C17_05730	COG2814	Major facilitator Superfamily
D9C17_05735	COG2433	Pfam Transposase IS66
D9C17_05740	COG0577	efflux transmembrane transporter activity
D9C17_05745	COG1136	(ABC) transporter
D9C17_05750	COG2205	protein histidine kinase activity
D9C17_05755	COG0745	RESPONSE REGULATOR receiver
D9C17_05760	COG0577	efflux transmembrane transporter activity
D9C17_05765	COG1136	(ABC) transporter
D9C17_05780	COG1131	(ABC) transporter
D9C17_05785	COG1725	Transcriptional regulator
D9C17_05800	COG1242	4 iron, 4 sulfur cluster binding
D9C17_05805	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9C17_05815	COG2267	carboxylic ester hydrolase activity
D9C17_05820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9C17_05825	COG1113	amino acid transport
D9C17_05830	COG0367	asparagine synthase
D9C17_05835	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9C17_05840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9C17_05850	COG1506	peptidase
D9C17_05855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C17_05860	COG1116	anion transmembrane transporter activity
D9C17_05865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C17_05870	COG0494	nUDIX hydrolase
D9C17_05875	COG4824	toxin secretion phage lysis holin
D9C17_05880	COG0783	Belongs to the Dps family
D9C17_05895	COG1854	S-ribosylhomocysteine lyase activity
D9C17_05900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9C17_05905	COG0288	reversible hydration of carbon dioxide
D9C17_05910	COG0254	rRNA binding
D9C17_05915	COG1271	oxidase subunit
D9C17_05920	COG1294	oxidase, subunit
D9C17_05930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C17_05935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C17_05935	COG1321	iron dependent repressor
D9C17_05940	COG1121	(ABC) transporter
D9C17_05945	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C17_05950	COG4948	Mandelate Racemase Muconate Lactonizing
D9C17_05955	COG0318	PFAM AMP-dependent synthetase and ligase
D9C17_05960	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9C17_05965	COG0596	Alpha beta hydrolase
D9C17_05970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9C17_05975	COG1169	isochorismate synthase
D9C17_05980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C17_05985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C17_05990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C17_05995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C17_06000	COG0438	transferase activity, transferring glycosyl groups
D9C17_06010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C17_06015	COG0438	transferase activity, transferring glycosyl groups
D9C17_06020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C17_06025	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9C17_06030	COG0058	SHG alpha-glucan phosphorylase activity
D9C17_06035	COG0297	glycogen (starch) synthase activity
D9C17_06040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C17_06045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C17_06050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9C17_06175	COG3859	Proton-coupled thiamine transporter YuaJ
D9C17_06180	COG1247	-acetyltransferase
D9C17_06185	COG2268	Band 7 protein
D9C17_06190	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9C17_06195	COG2318	DinB family
D9C17_06205	COG1454	alcohol dehydrogenase
D9C17_06215	COG1510	regulation of RNA biosynthetic process
D9C17_06225	COG0569	domain protein
D9C17_06230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C17_06235	COG4682	membrane
D9C17_06240	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C17_06245	COG0477	Major facilitator Superfamily
D9C17_06250	COG5553	Cysteine dioxygenase type I
D9C17_06260	COG1968	undecaprenyl-diphosphatase activity
D9C17_06265	COG0628	permease
D9C17_06270	COG0673	inositol 2-dehydrogenase activity
D9C17_06275	COG4806	L-rhamnose isomerase
D9C17_06280	COG3254	rhamnose metabolic process
D9C17_06285	COG1070	Carbohydrate kinase
D9C17_06290	COG1349	DNA-binding transcription factor activity
D9C17_06295	COG3347	Dehydrogenase
D9C17_06295	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_06310	COG0840	transmembrane signaling receptor activity
D9C17_06320	COG0840	transmembrane signaling receptor activity
D9C17_06335	COG0432	Pfam Uncharacterised protein family UPF0047
D9C17_06345	COG0366	Alpha amylase catalytic
D9C17_06350	COG1253	flavin adenine dinucleotide binding
D9C17_06355	COG2738	Putative neutral zinc metallopeptidase
D9C17_06370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9C17_06385	COG0166	Belongs to the GPI family
D9C17_06390	COG1979	alcohol dehydrogenase
D9C17_06395	COG1979	alcohol dehydrogenase
D9C17_06400	COG2155	Conserved Protein
D9C17_06405	COG1098	S1 RNA binding domain
D9C17_06410	COG0436	Aminotransferase
D9C17_06415	COG1522	sequence-specific DNA binding
D9C17_06420	COG2267	carboxylic ester hydrolase activity
D9C17_06430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9C17_06435	COG2205	protein histidine kinase activity
D9C17_06445	COG5018	Exonuclease
D9C17_06455	COG2814	Major facilitator Superfamily
D9C17_06460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C17_06475	COG3290	protein histidine kinase activity
D9C17_06480	COG4565	transcriptional regulatory protein
D9C17_06505	COG3493	citrate carrier protein
D9C17_06515	COG2111	Na H antiporter
D9C17_06515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C17_06520	COG2111	Na H antiporter
D9C17_06525	COG1006	Multisubunit Na H antiporter MnhC subunit
D9C17_06530	COG0651	ATP synthesis coupled electron transport
D9C17_06535	COG1863	multisubunit Na H antiporter MnhE subunit
D9C17_06540	COG2212	antiporter activity
D9C17_06545	COG1320	monovalent cation:proton antiporter activity
D9C17_06550	COG2050	protein possibly involved in aromatic compounds catabolism
D9C17_06555	COG2197	response regulator
D9C17_06560	COG4585	Histidine kinase
D9C17_06570	COG0142	geranyltranstransferase activity
D9C17_06590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9C17_06595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9C17_06600	COG1335	isochorismatase
D9C17_06605	COG5506	Protein of unknown function (DUF1694)
D9C17_06620	COG0628	permease
D9C17_06635	COG1418	mRNA catabolic process
D9C17_06640	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_06650	COG1511	domain protein
D9C17_06655	COG1674	ftsk spoiiie
D9C17_06655	COG0433	COG0433 Predicted ATPase
D9C17_06660	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C17_06665	COG5417	Belongs to the EsaB family
D9C17_06670	COG4842	Belongs to the WXG100 family
D9C17_06680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C17_06680	COG2508	Transcriptional regulator
D9C17_06685	COG0686	Belongs to the AlaDH PNT family
D9C17_06690	COG5634	Uncharacterized conserved protein (DUF2278)
D9C17_06695	COG3251	PFAM MbtH domain protein
D9C17_06700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C17_06705	COG3433	isochorismatase activity
D9C17_06705	COG1535	isochorismatase
D9C17_06710	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9C17_06715	COG1169	isochorismate synthase
D9C17_06720	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_06725	COG2819	hydrolase of the alpha beta superfamily
D9C17_06730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C17_06735	COG1268	BioY protein
D9C17_06740	COG2056	Na+-H+ antiporter family
D9C17_06745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9C17_06750	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9C17_06755	COG3584	3D domain protein
D9C17_06770	COG1252	NADH dehydrogenase
D9C17_06775	COG0492	ferredoxin-NADP+ reductase activity
D9C17_06785	COG0516	GMP reductase activity
D9C17_06790	COG2808	Putative FMN-binding domain
D9C17_06795	COG0456	acetyltransferase
D9C17_06895	COG0582	viral genome integration into host DNA
D9C17_06905	COG4974	Belongs to the 'phage' integrase family
D9C17_06910	COG0316	Belongs to the HesB IscA family
D9C17_06920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C17_06925	COG4844	belongs to the
D9C17_06930	COG1252	NADH dehydrogenase
D9C17_06935	COG4837	Protein of unknown function (DUF1462)
D9C17_06940	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9C17_06945	COG4946	Tricorn protease homolog
D9C17_06945	COG1506	peptidase
D9C17_06945	COG0823	Involved in the tonB-independent uptake of proteins
D9C17_06950	COG0083	homoserine kinase activity
D9C17_06955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9C17_06960	COG0460	homoserine dehydrogenase
D9C17_06965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C17_06970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C17_06975	COG0647	UMP catabolic process
D9C17_06980	COG2445	Protein of unknown function DUF86
D9C17_06985	COG4470	Protein conserved in bacteria
D9C17_06995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9C17_07000	COG0739	heme binding
D9C17_07010	COG3377	Domain of unknown function (DUF1805)
D9C17_07015	COG0737	Belongs to the 5'-nucleotidase family
D9C17_07020	COG0730	response to heat
D9C17_07025	COG1801	Protein of unknown function DUF72
D9C17_07035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C17_07040	COG2508	Transcriptional regulator
D9C17_07045	COG2233	PERMEase
D9C17_07050	COG2233	PERMEase
D9C17_07055	COG3195	allantoin biosynthetic process
D9C17_07055	COG3648	Uricase
D9C17_07060	COG2351	hydroxyisourate hydrolase activity
D9C17_07070	COG2080	2 iron, 2 sulfur cluster binding
D9C17_07075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9C17_07080	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9C17_07085	COG2068	MobA-Related Protein
D9C17_07090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9C17_07095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9C17_07100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C17_07110	COG2356	endonuclease I
D9C17_07115	COG3842	ATPase activity
D9C17_07120	COG2188	Transcriptional regulator
D9C17_07125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C17_07135	COG1175	transmembrane transport
D9C17_07140	COG1653	transport
D9C17_07145	COG2222	sugar isomerase
D9C17_07150	COG0322	excinuclease ABC activity
D9C17_07155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C17_07170	COG0346	lactoylglutathione lyase activity
D9C17_07175	COG0640	Transcriptional regulator
D9C17_07180	COG0719	Fe-S assembly protein
D9C17_07185	COG0822	iron-sulfur transferase activity
D9C17_07190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C17_07195	COG0719	Fe-S assembly protein
D9C17_07200	COG0396	ATPase activity
D9C17_07220	COG1464	Belongs to the NlpA lipoprotein family
D9C17_07225	COG2011	ABC-type metal ion transport system permease component
D9C17_07230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9C17_07240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_07245	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C17_07255	COG0509	glycine decarboxylation via glycine cleavage system
D9C17_07260	COG1393	Belongs to the ArsC family
D9C17_07265	COG1960	acyl-CoA dehydrogenase activity
D9C17_07270	COG0183	Belongs to the thiolase family
D9C17_07275	COG1024	Enoyl-CoA hydratase
D9C17_07275	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C17_07295	COG5577	PFAM Coat F domain
D9C17_07300	COG1846	Transcriptional regulator
D9C17_07305	COG0477	Major facilitator Superfamily
D9C17_07310	COG1942	4-Oxalocrotonate Tautomerase
D9C17_07315	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_07320	COG0583	DNA-binding transcription factor activity
D9C17_07330	COG1120	ATPase activity
D9C17_07350	COG1131	(ABC) transporter
D9C17_07400	COG0783	Belongs to the Dps family
D9C17_07405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C17_07410	COG0745	RESPONSE REGULATOR receiver
D9C17_07415	COG2770	Histidine kinase
D9C17_07415	COG2205	protein histidine kinase activity
D9C17_07425	COG1309	transcriptional regulator
D9C17_07430	COG0114	fumarate hydratase activity
D9C17_07440	COG0697	spore germination
D9C17_07445	COG0814	amino acid
D9C17_07455	COG2197	response regulator
D9C17_07460	COG4585	Histidine kinase
D9C17_07465	COG4758	membrane
D9C17_07470	COG3595	metallopeptidase activity
D9C17_07475	COG1842	Phage shock protein A
D9C17_07480	COG4758	membrane
D9C17_07485	COG2814	Major facilitator Superfamily
D9C17_07490	COG2096	Adenosyltransferase
D9C17_07495	COG1120	ATPase activity
D9C17_07500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_07505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C17_07510	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_07515	COG3386	PFAM SMP-30 Gluconolaconase
D9C17_07520	COG2205	protein histidine kinase activity
D9C17_07525	COG0745	RESPONSE REGULATOR receiver
D9C17_07545	COG2140	Oxalate decarboxylase
D9C17_07555	COG0577	efflux transmembrane transporter activity
D9C17_07560	COG1136	(ABC) transporter
D9C17_07565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C17_07570	COG1120	ATPase activity
D9C17_07575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_07580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_07585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C17_07595	COG0531	amino acid
D9C17_07610	COG1988	membrane-bound metal-dependent
D9C17_07615	COG1368	sulfuric ester hydrolase activity
D9C17_07620	COG1910	domain protein
D9C17_07625	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9C17_07630	COG4149	molybdate abc transporter
D9C17_07635	COG0656	L-ascorbic acid biosynthetic process
D9C17_07645	COG0025	NhaP-type Na H and K H
D9C17_07650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C17_07655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C17_07660	COG3973	AAA domain
D9C17_07670	COG2860	membrane
D9C17_07675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9C17_07680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9C17_07685	COG2217	Heavy metal translocating P-type atpase
D9C17_07690	COG2217	Heavy metal translocating P-type atpase
D9C17_07695	COG2608	mercury ion transmembrane transporter activity
D9C17_07700	COG1937	Protein conserved in bacteria
D9C17_07705	COG0673	inositol 2-dehydrogenase activity
D9C17_07715	COG1289	transmembrane transporter activity
D9C17_07725	COG2076	Multidrug Resistance protein
D9C17_07730	COG1309	transcriptional regulator
D9C17_07735	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_07745	COG5444	nuclease activity
D9C17_07760	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_07760	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C17_07765	COG4824	toxin secretion phage lysis holin
D9C17_07790	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C17_07790	COG3942	CHAP domain
D9C17_08015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9C17_08020	COG0557	exoribonuclease II activity
D9C17_08025	COG1647	Serine aminopeptidase, S33
D9C17_08030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C17_08035	COG0596	Alpha beta hydrolase
D9C17_08040	COG1476	TRANSCRIPTIONal
D9C17_08045	COG1396	sequence-specific DNA binding
D9C17_08050	COG1396	sequence-specific DNA binding
D9C17_08055	COG1733	regulation of RNA biosynthetic process
D9C17_08060	COG0840	transmembrane signaling receptor activity
D9C17_08065	COG1174	glycine betaine transport
D9C17_08070	COG1732	Glycine betaine
D9C17_08075	COG1174	glycine betaine transport
D9C17_08080	COG1125	glycine betaine transport
D9C17_08080	COG0517	IMP dehydrogenase activity
D9C17_08085	COG1510	regulation of RNA biosynthetic process
D9C17_08090	COG1174	glycine betaine transport
D9C17_08095	COG1732	Glycine betaine
D9C17_08100	COG1174	glycine betaine transport
D9C17_08105	COG0517	IMP dehydrogenase activity
D9C17_08105	COG1125	glycine betaine transport
D9C17_08110	COG1510	regulation of RNA biosynthetic process
D9C17_08115	COG2095	MarC family integral membrane protein
D9C17_08125	COG3064	Membrane
D9C17_08130	COG4640	response to antibiotic
D9C17_08135	COG0456	acetyltransferase
D9C17_08140	COG0148	phosphopyruvate hydratase activity
D9C17_08145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9C17_08150	COG0149	triose-phosphate isomerase activity
D9C17_08155	COG0126	phosphoglycerate kinase activity
D9C17_08160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C17_08165	COG2390	Transcriptional regulator
D9C17_08170	COG2814	Major facilitator Superfamily
D9C17_08175	COG1609	Transcriptional regulator
D9C17_08180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C17_08190	COG0583	DNA-binding transcription factor activity
D9C17_08195	COG0697	spore germination
D9C17_08200	COG1113	amino acid transport
D9C17_08210	COG1556	Lactate utilization protein
D9C17_08215	COG1139	Iron-sulfur cluster binding protein
D9C17_08220	COG0247	lactate metabolic process
D9C17_08225	COG2197	response regulator
D9C17_08230	COG4585	Histidine kinase
D9C17_08235	COG0842	Transport permease protein
D9C17_08240	COG1131	(ABC) transporter
D9C17_08260	COG0596	Alpha beta hydrolase
D9C17_08265	COG2208	phosphoserine phosphatase activity
D9C17_08270	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9C17_08275	COG1874	Beta-galactosidase
D9C17_08280	COG3833	ABC-type maltose transport systems, permease component
D9C17_08285	COG1175	transmembrane transport
D9C17_08290	COG2182	Extracellular solute-binding protein
D9C17_08295	COG1609	Transcriptional regulator
D9C17_08300	COG2186	Transcriptional regulator
D9C17_08305	COG1620	l-lactate permease
D9C17_08310	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9C17_08320	COG5039	Polysaccharide pyruvyl transferase
D9C17_08325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C17_08330	COG0110	maltose O-acetyltransferase activity
D9C17_08335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9C17_08340	COG2244	polysaccharide biosynthetic process
D9C17_08345	COG1216	Glycosyl transferase, family 2
D9C17_08350	COG5039	Polysaccharide pyruvyl transferase
D9C17_08355	COG1216	Glycosyl transferase, family 2
D9C17_08365	COG0438	transferase activity, transferring glycosyl groups
D9C17_08370	COG1215	transferase activity, transferring glycosyl groups
D9C17_08375	COG0438	transferase activity, transferring glycosyl groups
D9C17_08380	COG1086	Polysaccharide biosynthesis protein
D9C17_08385	COG0489	protein tyrosine kinase activity
D9C17_08390	COG3944	biosynthesis protein
D9C17_08395	COG1396	sequence-specific DNA binding
D9C17_08400	COG2272	Belongs to the type-B carboxylesterase lipase family
D9C17_08410	COG3479	Phenolic acid decarboxylase
D9C17_08425	COG1794	racemase activity, acting on amino acids and derivatives
D9C17_08435	COG1621	beta-fructofuranosidase activity
D9C17_08440	COG1621	beta-fructofuranosidase activity
D9C17_08445	COG0531	amino acid
D9C17_08450	COG1309	transcriptional regulator
D9C17_08455	COG2076	Multidrug Resistance protein
D9C17_08460	COG2076	Multidrug Resistance protein
D9C17_08480	COG1674	ftsk spoiiie
D9C17_08500	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_08500	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C17_08500	COG1388	LysM domain
D9C17_08535	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C17_08615	COG0582	viral genome integration into host DNA
D9C17_08715	COG4974	Belongs to the 'phage' integrase family
D9C17_08725	COG0740	serine-type endopeptidase activity
D9C17_08730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C17_08735	COG0366	Alpha amylase catalytic
D9C17_08740	COG1554	hydrolase, family 65, central catalytic
D9C17_08745	COG5521	maltodextrose utilization protein MalA
D9C17_08750	COG3833	ABC-type maltose transport systems, permease component
D9C17_08755	COG1175	transmembrane transport
D9C17_08760	COG2182	Extracellular solute-binding protein
D9C17_08770	COG1609	Transcriptional regulator
D9C17_08775	COG1611	Belongs to the LOG family
D9C17_08785	COG0659	secondary active sulfate transmembrane transporter activity
D9C17_08790	COG0288	reversible hydration of carbon dioxide
D9C17_08795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C17_08800	COG0577	efflux transmembrane transporter activity
D9C17_08805	COG1136	(ABC) transporter
D9C17_08810	COG5002	protein histidine kinase activity
D9C17_08815	COG0745	RESPONSE REGULATOR receiver
D9C17_08825	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9C17_08830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_08835	COG1481	regulation of sporulation
D9C17_08840	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9C17_08845	COG1660	Displays ATPase and GTPase activities
D9C17_08850	COG1051	belongs to the nudix hydrolase family
D9C17_08855	COG0492	ferredoxin-NADP+ reductase activity
D9C17_08860	COG3883	PFAM NLP P60 protein
D9C17_08860	COG0791	NLP P60 protein
D9C17_08865	COG0457	Tetratricopeptide repeat
D9C17_08870	COG1132	(ABC) transporter
D9C17_08890	COG0140	phosphoribosyl-ATP diphosphatase activity
D9C17_08890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9C17_08895	COG0107	imidazoleglycerol-phosphate synthase activity
D9C17_08900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9C17_08905	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9C17_08910	COG0131	Imidazoleglycerol-phosphate dehydratase
D9C17_08915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9C17_08920	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9C17_08925	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9C17_08930	COG4990	cell redox homeostasis
D9C17_08935	COG5297	Belongs to the glycosyl hydrolase family 6
D9C17_08950	COG0546	phosphoglycolate phosphatase activity
D9C17_08955	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9C17_08960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9C17_08965	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9C17_08970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9C17_08975	COG0363	glucosamine-6-phosphate deaminase activity
D9C17_08985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9C17_09000	COG1950	PFAM Membrane protein of
D9C17_09005	COG1983	PspC domain protein
D9C17_09010	COG3595	metallopeptidase activity
D9C17_09025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C17_09030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9C17_09035	COG0556	nucleotide-excision repair
D9C17_09040	COG4897	Protein conserved in bacteria
D9C17_09045	COG3848	Pyruvate phosphate dikinase
D9C17_09045	COG0574	Belongs to the PEP-utilizing enzyme family
D9C17_09050	COG1309	transcriptional regulator
D9C17_09055	COG2814	Major facilitator Superfamily
D9C17_09060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C17_09070	COG0793	Belongs to the peptidase S41A family
D9C17_09070	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_09075	COG2177	Part of the ABC transporter FtsEX involved in
D9C17_09080	COG2884	Cell division ATP-binding protein ftsE
D9C17_09085	COG2010	Cytochrome c
D9C17_09090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C17_09100	COG0653	protein targeting
D9C17_09105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9C17_09120	COG1516	flagellar protein fliS
D9C17_09125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9C17_09130	COG1334	flagellar protein FlaG
D9C17_09135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C17_09140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9C17_09145	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9C17_09155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C17_09160	COG1256	bacterial-type flagellum assembly
D9C17_09160	COG4786	Flagellar basal body rod
D9C17_09165	COG3418	PFAM FlgN family protein
D9C17_09170	COG2747	anti-sigma28 factor FlgM
D9C17_09180	COG1040	competence protein
D9C17_09190	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9C17_09195	COG1307	EDD domain protein, DegV family
D9C17_09200	COG2197	response regulator
D9C17_09205	COG4585	Histidine kinase
D9C17_09210	COG1739	Uncharacterized protein family UPF0029
D9C17_09215	COG1316	TRANSCRIPTIONal
D9C17_09250	COG1131	(ABC) transporter
D9C17_09260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C17_09265	COG0438	transferase activity, transferring glycosyl groups
D9C17_09270	COG1215	transferase activity, transferring glycosyl groups
D9C17_09275	COG3206	protein involved in exopolysaccharide biosynthesis
D9C17_09280	COG3307	-O-antigen
D9C17_09290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C17_09295	COG0297	glycogen (starch) synthase activity
D9C17_09295	COG0438	transferase activity, transferring glycosyl groups
D9C17_09300	COG2244	polysaccharide biosynthetic process
D9C17_09315	COG2247	cell wall binding repeat
D9C17_09315	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C17_09320	COG2385	sporulation resulting in formation of a cellular spore
D9C17_09320	COG2247	cell wall binding repeat
D9C17_09350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9C17_09355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C17_09365	COG1134	teichoic acid transport
D9C17_09370	COG1682	transport, permease protein
D9C17_09385	COG0463	Glycosyl transferase, family 2
D9C17_09385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C17_09390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C17_09395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9C17_09400	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D9C17_09405	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C17_09410	COG4193	domain, Protein
D9C17_09415	COG1482	cell wall glycoprotein biosynthetic process
D9C17_09420	COG0697	spore germination
D9C17_09425	COG0814	amino acid
D9C17_09440	COG1316	TRANSCRIPTIONal
D9C17_09445	COG0561	phosphatase activity
D9C17_09450	COG0791	NLP P60 protein
D9C17_09460	COG2843	Capsule synthesis protein
D9C17_09470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C17_09480	COG1609	Transcriptional regulator
D9C17_09485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C17_09490	COG1869	D-ribose catabolic process
D9C17_09495	COG1129	ABC transporter
D9C17_09500	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9C17_09505	COG1879	ABC-type sugar transport system periplasmic component
D9C17_09510	COG3103	Sh3 type 3 domain protein
D9C17_09520	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C17_09525	COG3527	Alpha-acetolactate decarboxylase
D9C17_09530	COG0028	Belongs to the TPP enzyme family
D9C17_09535	COG0583	DNA-binding transcription factor activity
D9C17_09540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C17_09555	COG5337	Spore coat protein CotH
D9C17_09565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C17_09575	COG0405	Gamma-glutamyltransferase
D9C17_09580	COG1522	sequence-specific DNA binding
D9C17_09585	COG2059	Chromate
D9C17_09590	COG2059	Chromate
D9C17_09605	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C17_09610	COG0583	DNA-binding transcription factor activity
D9C17_09640	COG5444	nuclease activity
D9C17_09665	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C17_09670	COG4464	protein tyrosine phosphatase activity
D9C17_09675	COG0489	protein tyrosine kinase activity
D9C17_09680	COG3944	biosynthesis protein
D9C17_09690	COG4715	Zinc finger, swim domain protein
D9C17_09695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C17_09705	COG0561	phosphatase activity
D9C17_09710	COG1349	DNA-binding transcription factor activity
D9C17_09715	COG0629	single-stranded DNA binding
D9C17_09730	COG3764	Sortase (surface protein transpeptidase)
D9C17_09735	COG0745	RESPONSE REGULATOR receiver
D9C17_09735	COG2972	Histidine kinase
D9C17_09740	COG1970	mechanosensitive ion channel activity
D9C17_09745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C17_09750	COG0457	Tetratricopeptide repeat
D9C17_09755	COG4786	Flagellar basal body rod
D9C17_09760	COG4786	Flagellar basal body rod
D9C17_09765	COG1077	Cell shape determining protein MreB Mrl
D9C17_09770	COG1609	Transcriptional regulator
D9C17_09780	COG1846	Transcriptional regulator
D9C17_09785	COG2814	Major facilitator Superfamily
D9C17_09790	COG3420	alginic acid biosynthetic process
D9C17_09795	COG1953	Uracil, thiamine, allantoin
D9C17_09800	COG0477	Major facilitator Superfamily
D9C17_09805	COG1335	isochorismatase
D9C17_09815	COG0004	ammonium transporteR
D9C17_09820	COG0347	Belongs to the P(II) protein family
D9C17_09825	COG0671	phosphoesterase, PA-phosphatase related
D9C17_09835	COG0739	heme binding
D9C17_09840	COG1247	-acetyltransferase
D9C17_09850	COG2089	acid synthase
D9C17_09860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C17_09865	COG0789	Transcriptional regulator
D9C17_09875	COG2910	NAD(P)H-binding
D9C17_09880	COG1959	2 iron, 2 sulfur cluster binding
D9C17_09885	COG0804	urea catabolic process
D9C17_09890	COG0832	Belongs to the urease beta subunit family
D9C17_09895	COG0831	urea catabolic process
D9C17_09910	COG3237	CsbD-like
D9C17_09915	COG1994	Peptidase M50
D9C17_09920	COG0457	Tetratricopeptide repeat
D9C17_09930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9C17_09935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9C17_09945	COG2304	oxidoreductase activity
D9C17_09955	COG2304	oxidoreductase activity
D9C17_09960	COG2385	sporulation resulting in formation of a cellular spore
D9C17_09965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C17_09975	COG4836	Membrane
D9C17_09985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9C17_09990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9C17_09995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9C17_10000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9C17_10005	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C17_10010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9C17_10015	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C17_10020	COG0356	it plays a direct role in the translocation of protons across the membrane
D9C17_10030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9C17_10035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9C17_10040	COG4475	Protein of unknown function (DUF436)
D9C17_10045	COG0698	ribose 5-phosphate isomerase
D9C17_10050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C17_10055	COG1971	Probably functions as a manganese efflux pump
D9C17_10060	COG0009	L-threonylcarbamoyladenylate synthase
D9C17_10065	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9C17_10085	COG2890	protein-(glutamine-N5) methyltransferase activity
D9C17_10090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9C17_10095	COG0346	lactoylglutathione lyase activity
D9C17_10100	COG0789	Transcriptional regulator
D9C17_10105	COG0679	Auxin Efflux Carrier
D9C17_10110	COG0281	malic enzyme
D9C17_10115	COG1435	thymidine kinase activity
D9C17_10120	COG0254	rRNA binding
D9C17_10125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9C17_10135	COG1494	fructose-1,6-bisphosphatase
D9C17_10140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C17_10145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9C17_10150	COG0191	fructose-bisphosphate aldolase activity
D9C17_10155	COG2204	response regulator
D9C17_10160	COG4821	SIS domain
D9C17_10165	COG0504	CTP synthase activity
D9C17_10170	COG3343	RNA polymerase activity
D9C17_10175	COG1960	acyl-CoA dehydrogenase activity
D9C17_10180	COG0247	lactate metabolic process
D9C17_10180	COG2181	nitrate reductase activity
D9C17_10185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C17_10190	COG4294	response to UV
D9C17_10200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C17_10210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C17_10220	COG2181	nitrate reductase activity
D9C17_10225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D9C17_10230	COG1140	nitrate reductase beta subunit
D9C17_10235	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D9C17_10240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C17_10250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C17_10255	COG2223	nitrite transmembrane transporter activity
D9C17_10260	COG0018	arginyl-trna synthetase
D9C17_10265	COG4506	Protein conserved in bacteria
D9C17_10280	COG0535	radical SAM domain protein
D9C17_10290	COG1131	(ABC) transporter
D9C17_10295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C17_10300	COG0612	Peptidase, M16
D9C17_10305	COG0612	Peptidase, M16
D9C17_10315	COG3391	amine dehydrogenase activity
D9C17_10320	COG3391	amine dehydrogenase activity
D9C17_10330	COG0457	Tetratricopeptide repeat
D9C17_10340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C17_10345	COG0010	Belongs to the arginase family
D9C17_10350	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9C17_10355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C17_10370	COG1994	Peptidase M50
D9C17_10375	COG1942	4-Oxalocrotonate Tautomerase
D9C17_10380	COG1846	Transcriptional regulator
D9C17_10385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C17_10395	COG0477	Major facilitator Superfamily
D9C17_10400	COG1959	2 iron, 2 sulfur cluster binding
D9C17_10405	COG3465	dGTPase activity
D9C17_10410	COG1078	dGTPase activity
D9C17_10415	COG4844	belongs to the
D9C17_10425	COG0697	spore germination
D9C17_10430	COG0095	Lipoate-protein ligase
D9C17_10435	COG0583	DNA-binding transcription factor activity
D9C17_10440	COG0280	phosphate acetyltransferase
D9C17_10450	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_10455	COG0436	Aminotransferase
D9C17_10460	COG2814	Major facilitator Superfamily
D9C17_10465	COG0151	Belongs to the GarS family
D9C17_10470	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_10475	COG1917	Cupin 2, conserved barrel domain protein
D9C17_10480	COG0077	Prephenate dehydratase
D9C17_10485	COG2814	Major facilitator Superfamily
D9C17_10490	COG0833	amino acid
D9C17_10495	COG4187	Peptidase family M20/M25/M40
D9C17_10500	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_10505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C17_10515	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D9C17_10520	COG1091	dTDP-4-dehydrorhamnose reductase activity
D9C17_10525	COG1088	dTDP-glucose 4,6-dehydratase activity
D9C17_10530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9C17_10535	COG3980	spore coat polysaccharide biosynthesis protein
D9C17_10540	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D9C17_10545	COG2089	acid synthase
D9C17_10550	COG0456	acetyltransferase
D9C17_10555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C17_10560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C17_10565	COG0463	Glycosyl transferase, family 2
D9C17_10580	COG2363	Small membrane protein
D9C17_10585	COG2233	PERMEase
D9C17_10595	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_10600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9C17_10605	COG1216	Glycosyl transferase, family 2
D9C17_10610	COG0351	phosphomethylpyrimidine kinase
D9C17_10620	COG1621	beta-fructofuranosidase activity
D9C17_10625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_10625	COG1263	PTS System
D9C17_10630	COG2116	formate transmembrane transporter activity
D9C17_10645	COG1404	Belongs to the peptidase S8 family
D9C17_10650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C17_10655	COG0778	Nitroreductase
D9C17_10660	COG0772	Belongs to the SEDS family
D9C17_10675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C17_10680	COG1845	cytochrome c oxidase, subunit III
D9C17_10685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C17_10690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C17_10695	COG2261	transglycosylase associated protein
D9C17_10700	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9C17_10705	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9C17_10710	COG2246	polysaccharide biosynthetic process
D9C17_10715	COG1309	transcriptional regulator
D9C17_10725	COG3162	membrane
D9C17_10730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C17_10735	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9C17_10740	COG2837	iron assimilation
D9C17_10745	COG2822	iron ion transport
D9C17_10750	COG0672	)-iron permease
D9C17_10755	COG0352	thiamine-phosphate diphosphorylase activity
D9C17_10760	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9C17_10765	COG0583	DNA-binding transcription factor activity
D9C17_10770	COG1380	Effector of murein hydrolase LrgA
D9C17_10775	COG1346	cytolysis
D9C17_10780	COG2814	Major facilitator Superfamily
D9C17_10785	COG4895	conserved protein (DUF2196)
D9C17_10790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9C17_10795	COG0346	lactoylglutathione lyase activity
D9C17_10805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C17_10815	COG1263	PTS System
D9C17_10815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_10820	COG3711	transcriptional antiterminator
D9C17_10825	COG1442	glycosyl transferase family 8
D9C17_10830	COG5522	Integral membrane protein (intg_mem_TP0381)
D9C17_10835	COG1846	Transcriptional regulator
D9C17_10840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C17_10845	COG2234	aminopeptidase activity
D9C17_10850	COG2357	RelA SpoT domain protein
D9C17_10860	COG1575	Belongs to the MenA family. Type 1 subfamily
D9C17_10880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C17_10885	COG1696	Membrane protein involved in D-alanine export
D9C17_10890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C17_10895	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9C17_10905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C17_10910	COG1486	melibiose metabolic process
D9C17_10915	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C17_10920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C17_10925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C17_10930	COG3711	transcriptional antiterminator
D9C17_10930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_10940	COG2094	Belongs to the DNA glycosylase MPG family
D9C17_10945	COG0753	catalase activity
D9C17_10950	COG2814	Major facilitator Superfamily
D9C17_10955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C17_10960	COG1131	(ABC) transporter
D9C17_10980	COG1595	DNA-templated transcription, initiation
D9C17_10985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C17_10990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9C17_10995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9C17_11000	COG4988	ABC transporter
D9C17_11005	COG1294	oxidase, subunit
D9C17_11010	COG1271	oxidase subunit
D9C17_11015	COG3493	citrate carrier protein
D9C17_11020	COG0501	Belongs to the peptidase M48B family
D9C17_11030	COG0726	polysaccharide deacetylase
D9C17_11035	COG3842	ATPase activity
D9C17_11040	COG2508	Transcriptional regulator
D9C17_11045	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_11050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C17_11065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9C17_11075	COG4585	Histidine kinase
D9C17_11080	COG2197	response regulator
D9C17_11085	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C17_11095	COG4894	glucomannan catabolic process
D9C17_11100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C17_11105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C17_11110	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_11115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C17_11120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C17_11125	COG2610	gluconate transmembrane transporter activity
D9C17_11130	COG0500	methyltransferase
D9C17_11135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C17_11150	COG0753	catalase activity
D9C17_11150	COG0693	protein deglycase activity
D9C17_11155	COG2851	Citrate transporter
D9C17_11160	COG2273	Hydrolase Family 16
D9C17_11165	COG3711	transcriptional antiterminator
D9C17_11180	COG2270	Major facilitator Superfamily
D9C17_11185	COG0513	Belongs to the DEAD box helicase family
D9C17_11190	COG3401	FG-GAP repeat protein
D9C17_11190	COG2755	lipolytic protein G-D-S-L family
D9C17_11320	COG0589	response to stress
D9C17_11330	COG2190	(PTS) system
D9C17_11330	COG1263	PTS System
D9C17_11330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_11350	COG5444	nuclease activity
D9C17_11370	COG0494	nUDIX hydrolase
D9C17_11375	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
D9C17_11380	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C17_11395	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9C17_11400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C17_11405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9C17_11410	COG2390	Transcriptional regulator
D9C17_11420	COG3192	ethanolamine utilization protein
D9C17_11425	COG2079	MmgE PrpD family protein
D9C17_11435	COG1126	abc transporter atp-binding protein
D9C17_11440	COG0765	amino acid transport
D9C17_11445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C17_11460	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9C17_11465	COG0561	phosphatase activity
D9C17_11495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C17_11500	COG5294	Protein conserved in bacteria
D9C17_11515	COG2205	protein histidine kinase activity
D9C17_11520	COG0745	RESPONSE REGULATOR receiver
D9C17_11525	COG0191	fructose-bisphosphate aldolase activity
D9C17_11530	COG1082	Xylose isomerase domain protein TIM barrel
D9C17_11535	COG1082	Xylose isomerase domain protein TIM barrel
D9C17_11540	COG0673	inositol 2-dehydrogenase activity
D9C17_11545	COG2814	Major facilitator Superfamily
D9C17_11550	COG1082	Xylose isomerase domain protein TIM barrel
D9C17_11555	COG3962	Belongs to the TPP enzyme family
D9C17_11560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C17_11580	COG1349	DNA-binding transcription factor activity
D9C17_11585	COG0667	Aldo Keto reductase
D9C17_11615	COG0326	Molecular chaperone. Has ATPase activity
D9C17_11680	COG1917	Cupin 2, conserved barrel domain protein
D9C17_11685	COG1309	transcriptional regulator
D9C17_11690	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_11695	COG1846	Transcriptional regulator
D9C17_11700	COG1380	Effector of murein hydrolase LrgA
D9C17_11705	COG1346	cytolysis
D9C17_11710	COG5039	Polysaccharide pyruvyl transferase
D9C17_11715	COG1929	Belongs to the glycerate kinase type-1 family
D9C17_11720	COG1802	Transcriptional regulator
D9C17_11725	COG1070	Carbohydrate kinase
D9C17_11730	COG2610	gluconate transmembrane transporter activity
D9C17_11735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C17_11740	COG0450	alkyl hydroperoxide reductase
D9C17_11745	COG3634	alkyl hydroperoxide reductase activity
D9C17_11750	COG2723	6-phospho-beta-galactosidase activity
D9C17_11765	COG2188	Transcriptional regulator
D9C17_11775	COG1131	(ABC) transporter
D9C17_11780	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D9C17_11795	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C17_11830	COG0210	DNA helicase
D9C17_11860	COG2963	transposase activity
D9C17_11895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9C17_11910	COG1063	alcohol dehydrogenase
D9C17_11930	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D9C17_11935	COG0456	acetyltransferase
D9C17_11940	COG0457	Tetratricopeptide repeat
D9C17_11950	COG0010	Belongs to the arginase family
D9C17_11955	COG0833	amino acid
D9C17_11960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C17_11980	COG5658	integral membrane protein
D9C17_11985	COG0640	Transcriptional regulator
D9C17_11990	COG3829	transcription factor binding
D9C17_12005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C17_12010	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9C17_12015	COG4853	Protein conserved in bacteria
D9C17_12020	COG4863	YycH protein
D9C17_12025	COG5002	protein histidine kinase activity
D9C17_12030	COG0745	RESPONSE REGULATOR receiver
D9C17_12060	COG0346	lactoylglutathione lyase activity
D9C17_12065	COG0305	Participates in initiation and elongation during chromosome replication
D9C17_12080	COG3093	addiction module antidote protein HigA
D9C17_12085	COG2807	transmembrane transport
D9C17_12090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C17_12095	COG0359	binds to the 23S rRNA
D9C17_12100	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9C17_12105	COG4241	membrane
D9C17_12120	COG1733	regulation of RNA biosynthetic process
D9C17_12125	COG1227	inorganic diphosphatase activity
D9C17_12140	COG2271	Major facilitator Superfamily
D9C17_12145	COG4978	Transcriptional regulator
D9C17_12145	COG0789	Transcriptional regulator
D9C17_12155	COG4319	ketosteroid isomerase
D9C17_12160	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C17_12175	COG1846	Transcriptional regulator
D9C17_12180	COG2153	protein acetylation
D9C17_12185	COG2364	Membrane
D9C17_12190	COG0456	acetyltransferase
D9C17_12195	COG2315	Protein conserved in bacteria
D9C17_12200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C17_12205	COG1331	Highly conserved protein containing a thioredoxin domain
D9C17_12210	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D9C17_12215	COG1331	Highly conserved protein containing a thioredoxin domain
D9C17_12220	COG1266	CAAX protease self-immunity
D9C17_12225	COG2814	Major facilitator Superfamily
D9C17_12225	COG0477	Major facilitator Superfamily
D9C17_12230	COG0346	lactoylglutathione lyase activity
D9C17_12235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C17_12240	COG0542	response to heat
D9C17_12255	COG0708	Exodeoxyribonuclease III
D9C17_12260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9C17_12265	COG0629	single-stranded DNA binding
D9C17_12270	COG0360	Binds together with S18 to 16S ribosomal RNA
D9C17_12275	COG0012	GTP binding
D9C17_12280	COG0243	molybdopterin cofactor binding
D9C17_12285	COG4481	Protein conserved in bacteria
D9C17_12290	COG3949	Membrane
D9C17_12300	COG1475	DNA binding
D9C17_12305	COG1192	Involved in chromosome partitioning
D9C17_12315	COG1475	DNA binding
D9C17_12320	COG0357	Ribosomal RNA small subunit methyltransferase G
D9C17_12325	COG0445	tRNA wobble uridine modification
D9C17_12330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9C17_12335	COG1847	R3H domain protein
D9C17_12340	COG0706	membrane insertase activity
D9C17_12345	COG0594	ribonuclease P activity
D9C17_12350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D9C17_12355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9C17_12360	COG0592	DNA-directed DNA polymerase activity
D9C17_12365	COG2501	S4 domain
D9C17_12370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9C17_12380	COG0187	DNA topoisomerase II activity
D9C17_12385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C17_12420	COG0517	IMP dehydrogenase activity
D9C17_12420	COG0516	GMP reductase activity
D9C17_12425	COG1686	Belongs to the peptidase S11 family
D9C17_12430	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9C17_12435	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9C17_12440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9C17_12450	COG1428	Deoxynucleoside kinase
D9C17_12455	COG1428	Deoxynucleoside kinase
D9C17_12460	COG1388	LysM domain
D9C17_12460	COG3858	chitin binding
D9C17_12465	COG1335	isochorismatase
D9C17_12470	COG0590	tRNA wobble adenosine to inosine editing
D9C17_12480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9C17_12485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9C17_12490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9C17_12535	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9C17_12540	COG3853	Toxic anion resistance protein (TelA)
D9C17_12545	COG1982	Orn Lys Arg decarboxylase major
D9C17_12550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C17_12555	COG3870	Protein conserved in bacteria
D9C17_12560	COG1728	Protein conserved in bacteria
D9C17_12565	COG0470	DNA polymerase III
D9C17_12570	COG1774	PSP1 C-terminal conserved region
D9C17_12575	COG4467	Involved in initiation control of chromosome replication
D9C17_12580	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9C17_12585	COG2827	Endonuclease containing a URI domain
D9C17_12590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9C17_12595	COG2002	toxin-antitoxin pair type II binding
D9C17_12600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C17_12600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C17_12605	COG0084	hydrolase, TatD family'
D9C17_12610	COG3583	domain protein
D9C17_12610	COG3584	3D domain protein
D9C17_12615	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C17_12620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9C17_12630	COG4466	Protein conserved in bacteria
D9C17_12640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9C17_12645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C17_12650	COG0251	oxidation-reduction process
D9C17_12655	COG2088	sporulation resulting in formation of a cellular spore
D9C17_12660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9C17_12665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9C17_12670	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9C17_12675	COG0193	aminoacyl-tRNA hydrolase activity
D9C17_12685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9C17_12690	COG2002	toxin-antitoxin pair type II binding
D9C17_12695	COG2244	polysaccharide biosynthetic process
D9C17_12705	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9C17_12720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9C17_12725	COG1098	S1 RNA binding domain
D9C17_12740	COG2208	phosphoserine phosphatase activity
D9C17_12745	COG2304	oxidoreductase activity
D9C17_12750	COG0515	serine threonine protein kinase
D9C17_12755	COG0037	tRNA processing
D9C17_12765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C17_12770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9C17_12775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9C17_12780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C17_12785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C17_12790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C17_12795	COG0512	Glutamine amidotransferase of anthranilate synthase
D9C17_12800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C17_12805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9C17_12810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9C17_12815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9C17_12820	COG1396	sequence-specific DNA binding
D9C17_12825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C17_12830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9C17_12910	COG4463	regulation of RNA biosynthetic process
D9C17_12915	COG3880	PFAM UvrB UvrC protein
D9C17_12920	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9C17_12925	COG0542	response to heat
D9C17_12930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9C17_12935	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9C17_12940	COG4956	integral membrane protein (PIN domain superfamily)
D9C17_12945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9C17_12950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9C17_12955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9C17_12965	COG1045	serine acetyltransferase
D9C17_12970	COG0215	cysteine-tRNA ligase activity
D9C17_12975	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9C17_12980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C17_12985	COG3688	RNA-binding protein containing a PIN domain
D9C17_12990	COG1595	DNA-templated transcription, initiation
D9C17_12995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C17_13000	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C17_13005	COG0250	Participates in transcription elongation, termination and antitermination
D9C17_13010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9C17_13015	COG0081	regulation of translation
D9C17_13020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9C17_13025	COG0222	ribosome binding
D9C17_13030	COG2813	Specifically methylates the guanine in position
D9C17_13035	COG0085	RNA polymerase activity
D9C17_13040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9C17_13045	COG1358	cellular component organization or biogenesis
D9C17_13050	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9C17_13055	COG0049	tRNA binding
D9C17_13060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9C17_13065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9C17_13070	COG0596	Alpha beta hydrolase
D9C17_13075	COG0051	transcription antitermination factor activity, RNA binding
D9C17_13080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9C17_13085	COG0088	Forms part of the polypeptide exit tunnel
D9C17_13090	COG0089	rRNA binding
D9C17_13095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9C17_13100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9C17_13105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9C17_13110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9C17_13115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9C17_13120	COG0255	Belongs to the universal ribosomal protein uL29 family
D9C17_13125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9C17_13130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9C17_13140	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9C17_13150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9C17_13155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9C17_13160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9C17_13165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9C17_13170	COG1841	ribosomal large subunit assembly
D9C17_13175	COG0200	Binds to the 23S rRNA
D9C17_13180	COG0201	protein transport
D9C17_13185	COG0563	adenylate kinase activity
D9C17_13190	COG0024	Methionine aminopeptidase
D9C17_13195	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9C17_13200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9C17_13205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9C17_13210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9C17_13215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9C17_13220	COG0202	RNA polymerase activity
D9C17_13225	COG0203	ribosomal protein L17
D9C17_13230	COG1122	ATPase activity
D9C17_13235	COG1122	ATPase activity
D9C17_13240	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C17_13245	COG0101	tRNA pseudouridine synthase activity
D9C17_13250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9C17_13255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9C17_13265	COG2226	methyltransferase
D9C17_13275	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C17_13280	COG0489	protein tyrosine kinase activity
D9C17_13290	COG2194	sulfuric ester hydrolase activity
D9C17_13295	COG0726	polysaccharide deacetylase
D9C17_13380	COG0659	secondary active sulfate transmembrane transporter activity
D9C17_13385	COG0385	Bile acid
D9C17_13390	COG2819	hydrolase of the alpha beta superfamily
D9C17_13395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_13400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_13405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C17_13410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C17_13410	COG2207	Transcriptional regulator
D9C17_13415	COG3876	Protein conserved in bacteria
D9C17_13420	COG1472	Belongs to the glycosyl hydrolase 3 family
D9C17_13425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C17_13430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_13430	COG1263	PTS System
D9C17_13435	COG1737	Transcriptional regulator
D9C17_13440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9C17_13445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_13450	COG1683	Conserved Protein
D9C17_13480	COG1595	DNA-templated transcription, initiation
D9C17_13485	COG5662	AntiSigma factor
D9C17_13490	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C17_13495	COG4856	YbbR-like protein
D9C17_13500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C17_13510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9C17_13525	COG2169	Transcriptional regulator
D9C17_13530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C17_13535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C17_13540	COG3002	Belongs to the UPF0753 family
D9C17_13545	COG0288	reversible hydration of carbon dioxide
D9C17_13555	COG5609	conserved protein (DUF2294)
D9C17_13565	COG0642	Histidine kinase
D9C17_13575	COG0515	serine threonine protein kinase
D9C17_13590	COG1113	amino acid transport
D9C17_13605	COG2602	Beta-lactamase
D9C17_13610	COG2124	cytochrome p450
D9C17_13620	COG0531	amino acid
D9C17_13625	COG0584	glycerophosphoryl diester phosphodiesterase
D9C17_13630	COG2271	Major facilitator Superfamily
D9C17_13645	COG1846	Transcriptional regulator
D9C17_13645	COG0456	acetyltransferase
D9C17_13665	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_13670	COG0697	spore germination
D9C17_13675	COG1917	Cupin 2, conserved barrel domain protein
D9C17_13675	COG2207	Transcriptional regulator
D9C17_13700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9C17_13705	COG3591	Belongs to the peptidase S1B family
D9C17_13715	COG0596	Alpha beta hydrolase
D9C17_13720	COG1183	phosphatidylcholine synthase activity
D9C17_13725	COG0586	Pfam SNARE associated Golgi protein
D9C17_13730	COG0688	phosphatidylethanolamine metabolic process
D9C17_13740	COG2312	Erythromycin esterase
D9C17_13745	COG2207	Transcriptional regulator
D9C17_13755	COG1301	dicarboxylic acid transport
D9C17_13760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_13760	COG2190	(PTS) system
D9C17_13760	COG1263	PTS System
D9C17_13765	COG0363	glucosamine-6-phosphate deaminase activity
D9C17_13780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C17_13785	COG0833	amino acid
D9C17_13790	COG2040	homocysteine
D9C17_13805	COG2066	Belongs to the glutaminase family
D9C17_13810	COG4191	Histidine kinase
D9C17_13815	COG0784	Response regulator, receiver
D9C17_13825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C17_13830	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_13835	COG2271	Major facilitator Superfamily
D9C17_13840	COG4948	Mandelate Racemase Muconate Lactonizing
D9C17_13845	COG2186	Transcriptional regulator
D9C17_13850	COG2721	sulfolactate sulfo-lyase activity
D9C17_13855	COG3173	Aminoglycoside phosphotransferase
D9C17_13865	COG0697	spore germination
D9C17_13870	COG0745	RESPONSE REGULATOR receiver
D9C17_13880	COG1131	(ABC) transporter
D9C17_13900	COG3773	Cell wall hydrolase
D9C17_13905	COG2304	oxidoreductase activity
D9C17_13915	COG3540	Alkaline phosphatase
D9C17_13920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C17_13925	COG0805	protein transport
D9C17_13930	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D9C17_13935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C17_13940	COG0477	Major facilitator Superfamily
D9C17_13945	COG1309	transcriptional regulator
D9C17_13950	COG0252	asparaginase activity
D9C17_13955	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C17_13960	COG1714	RDD family
D9C17_13965	COG1405	negative regulation of cell septum assembly
D9C17_13965	COG3012	SEC-C Motif Domain Protein
D9C17_13975	COG3279	Response regulator of the LytR AlgR family
D9C17_13985	COG1668	transmembrane transport
D9C17_13990	COG0667	Aldo Keto reductase
D9C17_14005	COG1595	DNA-templated transcription, initiation
D9C17_14010	COG1595	DNA-templated transcription, initiation
D9C17_14015	COG1876	peptidase activity
D9C17_14025	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_14030	COG0366	Alpha amylase catalytic
D9C17_14035	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C17_14040	COG1121	(ABC) transporter
D9C17_14045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C17_14060	COG2310	stress, protein
D9C17_14065	COG2310	stress, protein
D9C17_14070	COG2310	stress, protein
D9C17_14075	COG0861	Integral membrane protein TerC family
D9C17_14085	COG3853	Toxic anion resistance protein (TelA)
D9C17_14095	COG0477	Major facilitator Superfamily
D9C17_14100	COG2814	Major facilitator Superfamily
D9C17_14105	COG0640	Transcriptional regulator
D9C17_14110	COG0517	IMP dehydrogenase activity
D9C17_14110	COG4175	Glycine betaine
D9C17_14115	COG4176	ABC-type proline glycine betaine transport system permease component
D9C17_14120	COG2113	Glycine betaine
D9C17_14125	COG1473	amidohydrolase
D9C17_14130	COG1288	antiporter activity
D9C17_14145	COG0039	L-malate dehydrogenase activity
D9C17_14160	COG3403	YqcI/YcgG family
D9C17_14175	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9C17_14180	COG1660	Displays ATPase and GTPase activities
D9C17_14190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9C17_14200	COG2226	methyltransferase
D9C17_14205	COG0583	DNA-binding transcription factor activity
D9C17_14210	COG3458	cephalosporin-C deacetylase activity
D9C17_14215	COG3541	Predicted nucleotidyltransferase
D9C17_14220	COG0506	proline dehydrogenase activity
D9C17_14225	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_14230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C17_14235	COG2508	Transcriptional regulator
D9C17_14240	COG3689	TIGRFAM TIGR03943 family protein
D9C17_14245	COG0701	Predicted permease
D9C17_14250	COG2267	carboxylic ester hydrolase activity
D9C17_14255	COG0492	ferredoxin-NADP+ reductase activity
D9C17_14260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C17_14260	COG1587	Uroporphyrinogen-III synthase
D9C17_14265	COG2146	nitrite reductase [NAD(P)H] activity
D9C17_14270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C17_14275	COG0243	molybdopterin cofactor binding
D9C17_14280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C17_14285	COG2223	nitrite transmembrane transporter activity
D9C17_14295	COG1376	ErfK ybiS ycfS ynhG family protein
D9C17_14310	COG0765	amino acid transport
D9C17_14315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C17_14325	COG1714	RDD family
D9C17_14335	COG1846	Transcriptional regulator
D9C17_14350	COG2723	6-phospho-beta-galactosidase activity
D9C17_14360	COG3209	COG3209 Rhs family protein
D9C17_14370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9C17_14375	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9C17_14380	COG1733	regulation of RNA biosynthetic process
D9C17_14385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C17_14395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C17_14400	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9C17_14405	COG2814	Major facilitator Superfamily
D9C17_14415	COG0697	spore germination
D9C17_14420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C17_14430	COG2364	Membrane
D9C17_14435	COG1126	abc transporter atp-binding protein
D9C17_14440	COG0765	amino acid transport
D9C17_14445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C17_14450	COG0583	DNA-binding transcription factor activity
D9C17_14455	COG0163	prenyltransferase activity
D9C17_14460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9C17_14475	COG0596	Alpha beta hydrolase
D9C17_14480	COG3104	oligopeptide transport
D9C17_14485	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C17_14495	COG0697	spore germination
D9C17_14505	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C17_14510	COG1136	(ABC) transporter
D9C17_14515	COG0577	efflux transmembrane transporter activity
D9C17_14520	COG0745	RESPONSE REGULATOR receiver
D9C17_14525	COG3850	Histidine kinase
D9C17_14525	COG5002	protein histidine kinase activity
D9C17_14530	COG0457	Tetratricopeptide repeat
D9C17_14550	COG0527	aspartate kinase activity
D9C17_14555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_14560	COG4605	iron ion homeostasis
D9C17_14565	COG4604	ABC transporter, ATP-binding protein
D9C17_14570	COG4607	ABC-type enterochelin transport system periplasmic component
D9C17_14580	COG2814	Major facilitator Superfamily
D9C17_14585	COG1309	transcriptional regulator
D9C17_14590	COG0778	Nitroreductase
D9C17_14595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C17_14600	COG0640	Transcriptional regulator
D9C17_14605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C17_14610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9C17_14615	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_14620	COG4975	Glucose uptake
D9C17_14625	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_14630	COG4549	nuclear export factor GLE1
D9C17_14635	COG1276	copper resistance
D9C17_14635	COG2372	response to copper ion
D9C17_14640	COG1349	DNA-binding transcription factor activity
D9C17_14650	COG2213	PTS system mannitol-specific
D9C17_14655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_14660	COG0246	Mannitol dehydrogenase
D9C17_14665	COG0473	3-isopropylmalate dehydrogenase activity
D9C17_14670	COG0681	Belongs to the peptidase S26 family
D9C17_14680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C17_14690	COG0561	phosphatase activity
D9C17_14695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9C17_14700	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C17_14705	COG4336	lyase activity
D9C17_14710	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9C17_14715	COG1984	allophanate hydrolase subunit 2
D9C17_14720	COG1414	Transcriptional regulator
D9C17_14725	COG2755	lipolytic protein G-D-S-L family
D9C17_14735	COG2329	Antibiotic biosynthesis monooxygenase
D9C17_14740	COG0768	penicillin binding
D9C17_14745	COG4989	oxidoreductase activity
D9C17_14750	COG3711	transcriptional antiterminator
D9C17_14755	COG0318	PFAM AMP-dependent synthetase and ligase
D9C17_14760	COG2226	methyltransferase
D9C17_14765	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_14770	COG1917	Cupin 2, conserved barrel domain protein
D9C17_14775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_14780	COG3871	stress protein (general stress protein 26)
D9C17_14790	COG2814	Major facilitator Superfamily
D9C17_14795	COG1522	sequence-specific DNA binding
D9C17_14800	COG0551	DNA topoisomerase type I activity
D9C17_14800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C17_14805	COG0494	nUDIX hydrolase
D9C17_14810	COG0028	Belongs to the TPP enzyme family
D9C17_14840	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C17_14845	COG2261	transglycosylase associated protein
D9C17_14850	COG4876	unkown
D9C17_14855	COG2217	Heavy metal translocating P-type atpase
D9C17_14860	COG3729	General stress protein
D9C17_14865	COG0662	Cupin 2, conserved barrel domain protein
D9C17_14870	COG2329	Antibiotic biosynthesis monooxygenase
D9C17_14875	COG3546	catalase activity
D9C17_14880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9C17_14885	COG3290	protein histidine kinase activity
D9C17_14890	COG4565	transcriptional regulatory protein
D9C17_14895	COG1301	dicarboxylic acid transport
D9C17_14900	COG0628	permease
D9C17_14905	COG1131	(ABC) transporter
D9C17_14910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C17_14920	COG1960	acyl-CoA dehydrogenase activity
D9C17_14935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C17_14940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_14945	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9C17_14950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9C17_14960	COG0513	Belongs to the DEAD box helicase family
D9C17_14965	COG3402	PFAM membrane-flanked domain
D9C17_14970	COG3428	Bacterial PH domain
D9C17_14975	COG0705	Rhomboid family
D9C17_14980	COG0736	holo-[acyl-carrier-protein] synthase activity
D9C17_14985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9C17_14990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C17_14995	COG0864	Transcriptional regulator
D9C17_15000	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9C17_15005	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_15010	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_15015	COG2172	sigma factor antagonist activity
D9C17_15020	COG2208	phosphoserine phosphatase activity
D9C17_15025	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_15030	COG2172	sigma factor antagonist activity
D9C17_15035	COG1191	sigma factor activity
D9C17_15040	COG2208	phosphoserine phosphatase activity
D9C17_15055	COG1673	EVE domain
D9C17_15060	COG1846	Transcriptional regulator
D9C17_15065	COG2183	response to ionizing radiation
D9C17_15075	COG3091	SprT-like family
D9C17_15115	COG0582	viral genome integration into host DNA
D9C17_15120	COG2856	Zn peptidase
D9C17_15125	COG1396	sequence-specific DNA binding
D9C17_15155	COG1674	ftsk spoiiie
D9C17_15160	COG2946	Replication initiation factor
D9C17_15200	COG0433	COG0433 Predicted ATPase
D9C17_15210	COG5644	endopeptidase inhibitor activity
D9C17_15220	COG0741	lytic transglycosylase activity
D9C17_15220	COG0791	NLP P60 protein
D9C17_15235	COG0457	Tetratricopeptide repeat
D9C17_15270	COG0583	DNA-binding transcription factor activity
D9C17_15275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_15285	COG5444	nuclease activity
D9C17_15295	COG1476	TRANSCRIPTIONal
D9C17_15320	COG0693	protein deglycase activity
D9C17_15325	COG1278	Cold shock
D9C17_15330	COG1329	Transcriptional regulator
D9C17_15340	COG0697	spore germination
D9C17_15345	COG2207	Transcriptional regulator
D9C17_15345	COG1917	Cupin 2, conserved barrel domain protein
D9C17_15355	COG2207	Transcriptional regulator
D9C17_15355	COG3708	Transcriptional regulator
D9C17_15360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C17_15375	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D9C17_15390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_15395	COG1309	transcriptional regulator
D9C17_15400	COG0697	spore germination
D9C17_15405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C17_15410	COG2030	dehydratase
D9C17_15415	COG3545	Serine hydrolase
D9C17_15425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C17_15430	COG0640	Transcriptional regulator
D9C17_15435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C17_15445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_15450	COG0697	spore germination
D9C17_15455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C17_15460	COG0076	glutamate decarboxylase activity
D9C17_15465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C17_15470	COG0640	Transcriptional regulator
D9C17_15475	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C17_15490	COG4585	Histidine kinase
D9C17_15495	COG2197	response regulator
D9C17_15500	COG2409	Drug exporters of the RND superfamily
D9C17_15505	COG0596	Alpha beta hydrolase
D9C17_15510	COG1811	Na channel or pump
D9C17_15515	COG4978	Transcriptional regulator
D9C17_15515	COG0789	Transcriptional regulator
D9C17_15520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C17_15525	COG0778	Nitroreductase
D9C17_15530	COG0346	lactoylglutathione lyase activity
D9C17_15535	COG2259	Doxx family
D9C17_15540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_15565	COG2323	membrane
D9C17_15570	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C17_15585	COG1309	transcriptional regulator
D9C17_15595	COG0456	acetyltransferase
D9C17_15605	COG1113	amino acid transport
D9C17_15610	COG2318	DinB family
D9C17_15615	COG1846	Transcriptional regulator
D9C17_15620	COG1033	growth of symbiont in host cell
D9C17_15620	COG2409	Drug exporters of the RND superfamily
D9C17_15625	COG0778	Nitroreductase
D9C17_15630	COG1846	Transcriptional regulator
D9C17_15635	COG2814	Major facilitator Superfamily
D9C17_15640	COG0730	response to heat
D9C17_15645	COG1802	Transcriptional regulator
D9C17_15650	COG3858	chitin binding
D9C17_15650	COG1388	LysM domain
D9C17_15655	COG1819	glycosyl
D9C17_15665	COG1785	Belongs to the alkaline phosphatase family
D9C17_15670	COG5646	InterPro IPR014922
D9C17_15680	COG0454	-acetyltransferase
D9C17_15685	COG1078	dGTPase activity
D9C17_15690	COG1388	LysM domain
D9C17_15695	COG2814	Major facilitator Superfamily
D9C17_15700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C17_15715	COG2723	6-phospho-beta-galactosidase activity
D9C17_15720	COG2188	Transcriptional regulator
D9C17_15725	COG1940	carbohydrate kinase activity
D9C17_15735	COG4124	Belongs to the glycosyl hydrolase 26 family
D9C17_15780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9C17_15785	COG0802	atpase or kinase
D9C17_15790	COG1214	PFAM Peptidase M22, glycoprotease
D9C17_15795	COG0456	acetyltransferase
D9C17_15800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9C17_15810	COG0488	(ABC) transporter
D9C17_15815	COG0315	cyclic pyranopterin monophosphate synthase activity
D9C17_15820	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9C17_15825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C17_15830	COG0805	protein transport
D9C17_15845	COG1266	CAAX protease self-immunity
D9C17_15850	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9C17_15855	COG0459	protein refolding
D9C17_15870	COG0457	Tetratricopeptide repeat
D9C17_15875	COG1063	alcohol dehydrogenase
D9C17_15880	COG2211	Major facilitator Superfamily
D9C17_15885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C17_15895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C17_15900	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D9C17_15905	COG4260	virion core protein, lumpy skin disease virus
D9C17_15915	COG2814	Major facilitator Superfamily
D9C17_15920	COG1063	alcohol dehydrogenase
D9C17_15925	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9C17_15930	COG0823	Involved in the tonB-independent uptake of proteins
D9C17_15950	COG2267	carboxylic ester hydrolase activity
D9C17_15960	COG2132	Multicopper oxidase
D9C17_15965	COG1113	amino acid transport
D9C17_15975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C17_15980	COG0714	Associated with various cellular activities
D9C17_15985	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9C17_15990	COG1305	Transglutaminase-like
D9C17_15995	COG0519	Catalyzes the synthesis of GMP from XMP
D9C17_15995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9C17_16005	COG2252	PERMEase
D9C17_16010	COG3064	Membrane
D9C17_16020	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9C17_16030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9C17_16035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9C17_16040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9C17_16045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9C17_16050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C17_16055	COG0047	phosphoribosylformylglycinamidine synthase activity
D9C17_16060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C17_16065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9C17_16070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9C17_16075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9C17_16080	COG0138	bifunctional purine biosynthesis protein purh
D9C17_16085	COG0151	Belongs to the GarS family
D9C17_16090	COG1522	sequence-specific DNA binding
D9C17_16095	COG0531	amino acid
D9C17_16105	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C17_16110	COG1470	cell adhesion involved in biofilm formation
D9C17_16115	COG4496	protein, YerC YecD
D9C17_16120	COG0069	glutamate synthase activity
D9C17_16125	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9C17_16130	COG0210	DNA helicase
D9C17_16135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9C17_16140	COG4851	CamS sex pheromone cAM373 precursor
D9C17_16150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C17_16155	COG1285	pathogenesis
D9C17_16160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C17_16165	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C17_16170	COG0154	amidase activity
D9C17_16175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C17_16180	COG1309	transcriptional regulator
D9C17_16185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9C17_16190	COG1597	lipid kinase activity
D9C17_16195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C17_16230	COG5444	nuclease activity
D9C17_16240	COG0457	Tetratricopeptide repeat
D9C17_16250	COG0217	transcriptional regulatory protein
D9C17_16260	COG1309	transcriptional regulator
D9C17_16275	COG3546	catalase activity
D9C17_16280	COG0454	-acetyltransferase
D9C17_16290	COG5578	integral membrane protein
D9C17_16295	COG2972	Histidine kinase
D9C17_16305	COG1653	transport
D9C17_16310	COG1175	transmembrane transport
D9C17_16315	COG0395	ABC-type sugar transport system, permease component
D9C17_16320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C17_16325	COG2207	Transcriptional regulator
D9C17_16330	COG2755	lipolytic protein G-D-S-L family
D9C17_16340	COG5578	integral membrane protein
D9C17_16345	COG3401	FG-GAP repeat protein
D9C17_16350	COG3401	FG-GAP repeat protein
D9C17_16355	COG2755	lipolytic protein G-D-S-L family
D9C17_16370	COG1653	transport
D9C17_16375	COG4209	transmembrane transport
D9C17_16380	COG0395	ABC-type sugar transport system, permease component
D9C17_16385	COG1486	melibiose metabolic process
D9C17_16390	COG2323	membrane
D9C17_16395	COG2329	Antibiotic biosynthesis monooxygenase
D9C17_16400	COG0346	lactoylglutathione lyase activity
D9C17_16415	COG5583	Uncharacterized small protein (DUF2292)
D9C17_16420	COG0670	Belongs to the BI1 family
D9C17_16425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C17_16440	COG3328	transposase activity
D9C17_16450	COG2124	cytochrome p450
D9C17_16450	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C17_16460	COG1368	sulfuric ester hydrolase activity
D9C17_16465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9C17_16470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C17_16475	COG1442	glycosyl transferase family 8
D9C17_16480	COG1216	Glycosyl transferase, family 2
D9C17_16485	COG1442	glycosyl transferase family 8
D9C17_16490	COG2223	nitrite transmembrane transporter activity
D9C17_16495	COG1011	Hydrolase
D9C17_16500	COG0531	amino acid
D9C17_16505	COG1012	belongs to the aldehyde dehydrogenase family
D9C17_16510	COG0840	transmembrane signaling receptor activity
D9C17_16515	COG0488	(ABC) transporter
D9C17_16525	COG0789	Transcriptional regulator
D9C17_16530	COG2814	Major facilitator Superfamily
D9C17_16550	COG0488	(ABC) transporter
D9C17_16555	COG0513	Belongs to the DEAD box helicase family
D9C17_16565	COG3866	Pectate lyase
D9C17_16570	COG0471	metal ion transport
D9C17_16575	COG3290	protein histidine kinase activity
D9C17_16580	COG4565	transcriptional regulatory protein
D9C17_16585	COG3181	Tripartite tricarboxylate transporter family receptor
D9C17_16590	COG2851	Citrate transporter
D9C17_16595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C17_16600	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9C17_16605	COG1254	Belongs to the acylphosphatase family
D9C17_16610	COG2258	MOSC domain
D9C17_16630	COG0024	Methionine aminopeptidase
D9C17_16635	COG1263	PTS System
D9C17_16635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_16640	COG1368	sulfuric ester hydrolase activity
D9C17_16655	COG1115	amino acid carrier protein
D9C17_16670	COG0697	spore germination
D9C17_16675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_16675	COG1263	PTS System
D9C17_16680	COG0366	Alpha amylase catalytic
D9C17_16685	COG2188	Transcriptional regulator
D9C17_16690	COG0778	Nitroreductase
D9C17_16695	COG0737	Belongs to the 5'-nucleotidase family
D9C17_16700	COG0693	protein deglycase activity
D9C17_16710	COG2814	Major facilitator Superfamily
D9C17_16715	COG4840	Belongs to the UPF0435 family
D9C17_16720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C17_16725	COG4980	gas vesicle protein
D9C17_16730	COG1295	ribonuclease BN
D9C17_16735	COG0477	Major facilitator Superfamily
D9C17_16740	COG0387	Pfam Sodium calcium exchanger
D9C17_16750	COG0668	transmembrane transport
D9C17_16755	COG0535	radical SAM domain protein
D9C17_16765	COG0726	polysaccharide deacetylase
D9C17_16770	COG2084	Dehydrogenase
D9C17_16775	COG0598	Magnesium transport protein CorA
D9C17_16780	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C17_16785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C17_16795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C17_16800	COG4637	Psort location Cytoplasmic, score
D9C17_16810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C17_16815	COG0022	dehydrogenase e1 component
D9C17_16820	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C17_16825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C17_16830	COG3284	Transcriptional regulator
D9C17_16840	COG1742	UPF0060 membrane protein
D9C17_16865	COG4842	Belongs to the WXG100 family
D9C17_16870	COG1486	melibiose metabolic process
D9C17_16875	COG1737	Transcriptional regulator
D9C17_16880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_16880	COG1263	PTS System
D9C17_16885	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C17_16890	COG1132	(ABC) transporter
D9C17_16895	COG1132	(ABC) transporter
D9C17_16900	COG2259	Doxx family
D9C17_16905	COG2514	catechol 2,3-dioxygenase activity
D9C17_16910	COG1917	Cupin 2, conserved barrel domain protein
D9C17_16910	COG4977	sequence-specific DNA binding
D9C17_16915	COG2814	Major facilitator Superfamily
D9C17_16920	COG1082	Xylose isomerase domain protein TIM barrel
D9C17_16930	COG4585	Histidine kinase
D9C17_16935	COG2197	response regulator
D9C17_16945	COG0842	Transport permease protein
D9C17_16945	COG1511	domain protein
D9C17_16950	COG0842	Transport permease protein
D9C17_16955	COG1695	Transcriptional regulator
D9C17_16960	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C17_16965	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9C17_16970	COG1309	transcriptional regulator
D9C17_16975	COG2814	Major facilitator Superfamily
D9C17_16980	COG2318	DinB family
D9C17_16990	COG1846	Transcriptional regulator
D9C17_17000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C17_17005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_17010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C17_17015	COG0384	phenazine biosynthesis protein PhzF
D9C17_17020	COG0778	Nitroreductase
D9C17_17035	COG1090	epimerase
D9C17_17040	COG2137	regulation of response to DNA damage stimulus
D9C17_17050	COG2814	Major facilitator Superfamily
D9C17_17065	COG3103	Sh3 type 3 domain protein
D9C17_17070	COG5658	integral membrane protein
D9C17_17075	COG0596	Alpha beta hydrolase
D9C17_17080	COG0463	Glycosyl transferase, family 2
D9C17_17085	COG4485	Bacterial membrane protein, YfhO
D9C17_17090	COG1988	membrane-bound metal-dependent
D9C17_17095	COG1194	a g-specific adenine glycosylase
D9C17_17105	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_17120	COG3557	Belongs to the UPF0374 family
D9C17_17125	COG1132	(ABC) transporter
D9C17_17130	COG4129	membrane
D9C17_17135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C17_17140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9C17_17145	COG0735	belongs to the Fur family
D9C17_17255	COG4326	sporulation control protein
D9C17_17265	COG5577	PFAM Coat F domain
D9C17_17270	COG3340	Belongs to the peptidase S51 family
D9C17_17275	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9C17_17290	COG0753	catalase activity
D9C17_17295	COG1116	anion transmembrane transporter activity
D9C17_17300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C17_17305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C17_17310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C17_17320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9C17_17330	COG1476	TRANSCRIPTIONal
D9C17_17340	COG3382	B3 4 domain protein
D9C17_17345	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9C17_17355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9C17_17360	COG0789	Transcriptional regulator
D9C17_17365	COG1664	Polymer-forming cytoskeletal
D9C17_17370	COG1664	Polymer-forming cytoskeletal
D9C17_17375	COG2766	serine protein kinase
D9C17_17380	COG2718	Belongs to the UPF0229 family
D9C17_17385	COG1846	Transcriptional regulator
D9C17_17390	COG1566	PFAM secretion protein HlyD family protein
D9C17_17395	COG2814	Major facilitator Superfamily
D9C17_17400	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C17_17420	COG1725	Transcriptional regulator
D9C17_17425	COG1131	(ABC) transporter
D9C17_17430	COG1131	(ABC) transporter
D9C17_17435	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C17_17440	COG1278	Cold shock
D9C17_17450	COG1464	Belongs to the NlpA lipoprotein family
D9C17_17455	COG3706	GGDEF domain
D9C17_17460	COG1823	symporter activity
D9C17_17465	COG5444	nuclease activity
D9C17_17490	COG0582	viral genome integration into host DNA
D9C17_17495	COG2946	Replication initiation factor
D9C17_17545	COG5644	endopeptidase inhibitor activity
D9C17_17550	COG0741	lytic transglycosylase activity
D9C17_17550	COG0791	NLP P60 protein
D9C17_17570	COG0457	Tetratricopeptide repeat
D9C17_17595	COG1525	nuclease
D9C17_17595	COG4085	toxin activity
D9C17_17595	COG0737	Belongs to the 5'-nucleotidase family
D9C17_17600	COG3764	Sortase (surface protein transpeptidase)
D9C17_17605	COG0564	pseudouridine synthase activity
D9C17_17615	COG0517	IMP dehydrogenase activity
D9C17_17620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C17_17625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C17_17625	COG3153	acetyltransferase
D9C17_17630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C17_17635	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9C17_17640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9C17_17645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9C17_17650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9C17_17655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C17_17660	COG4585	Histidine kinase
D9C17_17660	COG2203	Gaf domain
D9C17_17665	COG2197	response regulator
D9C17_17670	COG0431	NADPH-dependent FMN reductase
D9C17_17685	COG1388	LysM domain
D9C17_17685	COG0791	NLP P60 protein
D9C17_17690	COG1959	2 iron, 2 sulfur cluster binding
D9C17_17695	COG0668	transmembrane transport
D9C17_17700	COG2719	SpoVR family
D9C17_17705	COG1785	Belongs to the alkaline phosphatase family
D9C17_17710	COG1388	LysM domain
D9C17_17710	COG0791	NLP P60 protein
D9C17_17715	COG0583	DNA-binding transcription factor activity
D9C17_17720	COG0372	Belongs to the citrate synthase family
D9C17_17725	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_17730	COG0531	amino acid
D9C17_17735	COG0733	neurotransmitter:sodium symporter activity
D9C17_17740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C17_17745	COG0456	acetyltransferase
D9C17_17760	COG1595	DNA-templated transcription, initiation
D9C17_17765	COG0667	Aldo Keto reductase
D9C17_17770	COG0204	Acyl-transferase
D9C17_17775	COG1253	flavin adenine dinucleotide binding
D9C17_17780	COG0789	Transcriptional regulator
D9C17_17790	COG1253	flavin adenine dinucleotide binding
D9C17_17795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C17_17800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C17_17805	COG0584	glycerophosphoryl diester phosphodiesterase
D9C17_17815	COG0668	transmembrane transport
D9C17_17820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9C17_17825	COG0726	polysaccharide deacetylase
D9C17_17830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C17_17835	COG1757	Na H antiporter
D9C17_17840	COG0589	response to stress
D9C17_17850	COG1132	(ABC) transporter
D9C17_17855	COG1132	(ABC) transporter
D9C17_17860	COG0702	epimerase
D9C17_17885	COG0189	ligase activity
D9C17_17890	COG0189	ligase activity
D9C17_17895	COG4399	Belongs to the UPF0754 family
D9C17_17900	COG3679	Belongs to the UPF0342 family
D9C17_17910	COG0561	phosphatase activity
D9C17_17915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C17_17920	COG0475	glutathione-regulated potassium exporter activity
D9C17_17925	COG0490	domain, Protein
D9C17_17935	COG1024	Enoyl-CoA hydratase
D9C17_17945	COG4152	abc transporter atp-binding protein
D9C17_17950	COG1668	transmembrane transport
D9C17_17955	COG0420	3'-5' exonuclease activity
D9C17_17960	COG4717	serine-type aminopeptidase activity
D9C17_17965	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9C17_17975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C17_18005	COG1846	Transcriptional regulator
D9C17_18010	COG4980	gas vesicle protein
D9C17_18025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9C17_18030	COG0537	adenosine 5'-monophosphoramidase activity
D9C17_18035	COG1131	(ABC) transporter
D9C17_18040	COG4473	ABC transporter
D9C17_18050	COG1473	amidohydrolase
D9C17_18055	COG3069	C4-dicarboxylate transmembrane transporter activity
D9C17_18065	COG2329	Antibiotic biosynthesis monooxygenase
D9C17_18070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C17_18075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9C17_18090	COG1309	transcriptional regulator
D9C17_18095	COG1511	domain protein
D9C17_18100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C17_18105	COG4377	Putative membrane peptidase family (DUF2324)
D9C17_18115	COG1363	Peptidase, m42
D9C17_18120	COG4405	Protein conserved in bacteria
D9C17_18125	COG1301	dicarboxylic acid transport
D9C17_18135	COG1234	tRNA 3'-trailer cleavage
D9C17_18140	COG0095	Lipoate-protein ligase
D9C17_18145	COG0702	epimerase
D9C17_18150	COG0318	PFAM AMP-dependent synthetase and ligase
D9C17_18160	COG0501	Belongs to the peptidase M48B family
D9C17_18170	COG0456	acetyltransferase
D9C17_18175	COG0604	alcohol dehydrogenase
D9C17_18180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C17_18185	COG0406	alpha-ribazole phosphatase activity
D9C17_18190	COG0183	Belongs to the thiolase family
D9C17_18195	COG0318	PFAM AMP-dependent synthetase and ligase
D9C17_18200	COG1268	BioY protein
D9C17_18205	COG0840	transmembrane signaling receptor activity
D9C17_18215	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_18225	COG4903	ComK protein
D9C17_18230	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_18240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C17_18255	COG0398	Pfam SNARE associated Golgi protein
D9C17_18260	COG0681	Belongs to the peptidase S26 family
D9C17_18265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C17_18270	COG1846	Transcriptional regulator
D9C17_18285	COG0738	Major facilitator superfamily
D9C17_18290	COG0673	inositol 2-dehydrogenase activity
D9C17_18295	COG0561	phosphatase activity
D9C17_18300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C17_18305	COG1609	Transcriptional regulator
D9C17_18310	COG3180	Ammonia monooxygenase
D9C17_18315	COG2814	Major facilitator Superfamily
D9C17_18315	COG0477	Major facilitator Superfamily
D9C17_18320	COG4533	DNA binding
D9C17_18340	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9C17_18345	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9C17_18350	COG1074	ATP-dependent DNA helicase activity
D9C17_18355	COG0420	3'-5' exonuclease activity
D9C17_18360	COG0419	ATPase involved in DNA repair
D9C17_18365	COG1403	HNH endonuclease
D9C17_18405	COG5337	Spore coat protein CotH
D9C17_18410	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9C17_18420	COG1404	Belongs to the peptidase S8 family
D9C17_18435	COG1562	ergosterol biosynthetic process
D9C17_18440	COG0534	Mate efflux family protein
D9C17_18445	COG2207	Transcriptional regulator
D9C17_18445	COG1917	Cupin 2, conserved barrel domain protein
D9C17_18450	COG1609	Transcriptional regulator
D9C17_18455	COG0673	inositol 2-dehydrogenase activity
D9C17_18460	COG2318	DinB family
D9C17_18465	COG1279	arginine transmembrane transporter activity
D9C17_18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C17_18475	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C17_18480	COG2267	carboxylic ester hydrolase activity
D9C17_18490	COG2153	protein acetylation
D9C17_18495	COG0646	methionine synthase
D9C17_18495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9C17_18500	COG1666	GTP binding
D9C17_18505	COG2996	Protein conserved in bacteria
D9C17_18515	COG1307	EDD domain protein, DegV family
D9C17_18520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C17_18535	COG0561	phosphatase activity
D9C17_18540	COG1073	alpha beta
D9C17_18545	COG2151	metal-sulfur cluster biosynthetic enzyme
D9C17_18565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9C17_18580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C17_18585	COG0505	Belongs to the CarA family
D9C17_18590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C17_18595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9C17_18615	COG2267	carboxylic ester hydrolase activity
D9C17_18625	COG1744	ABC transporter substrate-binding protein PnrA-like
D9C17_18640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C17_18645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C17_18650	COG5504	Zn-dependent protease
D9C17_18655	COG0444	Belongs to the ABC transporter superfamily
D9C17_18660	COG4608	Belongs to the ABC transporter superfamily
D9C17_18670	COG0601	transmembrane transport
D9C17_18675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C17_18685	COG0180	Tryptophanyl-tRNA synthetase
D9C17_18690	COG4166	transmembrane transport
D9C17_18695	COG0601	transmembrane transport
D9C17_18700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C17_18705	COG0444	Belongs to the ABC transporter superfamily
D9C17_18710	COG4608	Belongs to the ABC transporter superfamily
D9C17_18715	COG2814	Major facilitator Superfamily
D9C17_18720	COG0456	acetyltransferase
D9C17_18725	COG1393	Belongs to the ArsC family
D9C17_18730	COG0861	Integral membrane protein TerC family
D9C17_18740	COG4862	establishment of competence for transformation
D9C17_18750	COG4469	Competence protein
D9C17_18755	COG1164	Oligoendopeptidase f
D9C17_18775	COG2346	COG2346, Truncated hemoglobins
D9C17_18780	COG0741	lytic transglycosylase activity
D9C17_18785	COG4116	CYTH
D9C17_18795	COG2357	RelA SpoT domain protein
D9C17_18800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C17_18805	COG0564	pseudouridine synthase activity
D9C17_18810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9C17_18815	COG0569	domain protein
D9C17_18815	COG0475	glutathione-regulated potassium exporter activity
D9C17_18820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9C17_18825	COG0352	thiamine-phosphate diphosphorylase activity
D9C17_18830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C17_18835	COG2104	thiamine diphosphate biosynthetic process
D9C17_18840	COG2022	thiamine diphosphate biosynthetic process
D9C17_18845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C17_18850	COG0351	phosphomethylpyrimidine kinase
D9C17_18855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9C17_18910	COG0210	DNA helicase
D9C17_18920	COG2153	protein acetylation
D9C17_18925	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C17_18930	COG2382	esterase
D9C17_18935	COG0626	cystathionine gamma-synthase activity
D9C17_18940	COG0626	cystathionine gamma-synthase activity
D9C17_18945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_18950	COG5505	Protein of unknown function (DUF819)
D9C17_18985	COG1396	sequence-specific DNA binding
D9C17_19050	COG0457	Tetratricopeptide repeat
D9C17_19055	COG5444	nuclease activity
D9C17_19070	COG3328	transposase activity
D9C17_19130	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C17_19140	COG3711	transcriptional antiterminator
D9C17_19140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_19145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_19145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C17_19145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C17_19150	COG1482	cell wall glycoprotein biosynthetic process
D9C17_19165	COG3328	transposase activity
D9C17_19170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_19180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C17_19200	COG0109	protoheme IX farnesyltransferase activity
D9C17_19210	COG0726	polysaccharide deacetylase
D9C17_19225	COG5504	Zn-dependent protease
D9C17_19230	COG2205	protein histidine kinase activity
D9C17_19245	COG2427	Protein of unknown function (DUF1641)
D9C17_19255	COG1051	belongs to the nudix hydrolase family
D9C17_19270	COG1819	glycosyl
D9C17_19280	COG1587	Uroporphyrinogen-III synthase
D9C17_19285	COG0390	transport system, permease component
D9C17_19290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C17_19295	COG0697	spore germination
D9C17_19310	COG1252	NADH dehydrogenase
D9C17_19315	COG1904	glucuronate isomerase
D9C17_19320	COG2211	Major facilitator Superfamily
D9C17_19325	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9C17_19330	COG1063	alcohol dehydrogenase
D9C17_19335	COG1312	Catalyzes the dehydration of D-mannonate
D9C17_19340	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_19345	COG2271	Major facilitator Superfamily
D9C17_19350	COG1609	Transcriptional regulator
D9C17_19355	COG0246	Mannitol dehydrogenase
D9C17_19360	COG2721	sulfolactate sulfo-lyase activity
D9C17_19365	COG0730	response to heat
D9C17_19370	COG2318	DinB family
D9C17_19390	COG0457	Tetratricopeptide repeat
D9C17_19405	COG1388	LysM domain
D9C17_19405	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C17_19405	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_19415	COG4195	phage-related replication protein
D9C17_19420	COG3546	catalase activity
D9C17_19425	COG2856	Zn peptidase
D9C17_19430	COG1396	sequence-specific DNA binding
D9C17_19440	COG1522	sequence-specific DNA binding
D9C17_19445	COG1484	DNA-dependent DNA replication
D9C17_19465	COG1595	DNA-templated transcription, initiation
D9C17_19470	COG5484	DNA packaging
D9C17_19470	COG3728	DNA packaging
D9C17_19475	COG1783	phage Terminase large subunit
D9C17_19480	COG5518	Phage portal protein
D9C17_19485	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9C17_19490	COG4653	Phage capsid family
D9C17_19540	COG5412	phage tail tape measure protein
D9C17_19540	COG3953	SLT domain
D9C17_19540	COG5412	phage tail tape measure protein
D9C17_19540	COG3953	SLT domain
D9C17_19540	COG5412	phage tail tape measure protein
D9C17_19540	COG3953	SLT domain
D9C17_19545	COG1652	LysM domain
D9C17_19550	COG4193	domain, Protein
D9C17_19560	COG3628	GPW Gp25 family protein
D9C17_19565	COG3299	homolog of phage Mu protein gp47
D9C17_19570	COG3778	Protein conserved in bacteria
D9C17_19610	COG3409	Peptidoglycan-binding domain 1 protein
D9C17_19610	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C17_19630	COG0306	phosphate transporter
D9C17_19635	COG1392	Phosphate transport regulator
D9C17_19640	COG0531	amino acid
D9C17_19645	COG0346	lactoylglutathione lyase activity
D9C17_19650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C17_19655	COG0463	Glycosyl transferase, family 2
D9C17_19660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C17_19665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C17_19670	COG2362	D-Aminopeptidase
D9C17_19675	COG0601	transmembrane transport
D9C17_19680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C17_19685	COG0444	Belongs to the ABC transporter superfamily
D9C17_19690	COG4166	transmembrane transport
D9C17_19695	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C17_19700	COG4948	Mandelate Racemase Muconate Lactonizing
D9C17_19705	COG0791	NLP P60 protein
D9C17_19710	COG4608	Belongs to the ABC transporter superfamily
D9C17_19715	COG2706	6-phosphogluconolactonase activity
D9C17_19725	COG1607	acyl-coa hydrolase
D9C17_19730	COG1017	nitric oxide dioxygenase activity
D9C17_19730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9C17_19740	COG2323	membrane
D9C17_19745	COG2318	DinB family
D9C17_19750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C17_19755	COG2076	Multidrug Resistance protein
D9C17_19760	COG2076	Multidrug Resistance protein
D9C17_19765	COG0788	formyltetrahydrofolate deformylase activity
D9C17_19770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C17_19775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9C17_19780	COG1764	response to oxidative stress
D9C17_19785	COG1846	Transcriptional regulator
D9C17_19790	COG1764	response to oxidative stress
D9C17_19800	COG0590	tRNA wobble adenosine to inosine editing
D9C17_19805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C17_19810	COG1404	Belongs to the peptidase S8 family
D9C17_19815	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C17_19820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C17_19825	COG1122	ATPase activity
D9C17_19830	COG4721	ABC-type cobalt transport system, permease component
D9C17_19840	COG0745	RESPONSE REGULATOR receiver
D9C17_19845	COG3850	Histidine kinase
D9C17_19845	COG5002	protein histidine kinase activity
D9C17_19850	COG3212	peptidase
D9C17_19855	COG3212	peptidase
D9C17_19870	COG2239	Acts as a magnesium transporter
D9C17_19875	COG0789	Transcriptional regulator
D9C17_19890	COG1846	Transcriptional regulator
D9C17_19895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C17_19900	COG0726	polysaccharide deacetylase
D9C17_19905	COG1408	metallophosphoesterase
D9C17_19915	COG0463	Glycosyl transferase, family 2
D9C17_19920	COG1793	dna ligase
D9C17_19920	COG3285	dna ligase
D9C17_19925	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9C17_19930	COG5001	Diguanylate cyclase
D9C17_19930	COG3300	MHYT domain
D9C17_19935	COG0586	Pfam SNARE associated Golgi protein
D9C17_19940	COG0861	Integral membrane protein TerC family
D9C17_19945	COG1191	sigma factor activity
D9C17_19965	COG0501	Belongs to the peptidase M48B family
D9C17_19970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C17_19990	COG3594	Acyltransferase
D9C17_19995	COG5002	protein histidine kinase activity
D9C17_20000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C17_20010	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9C17_20015	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9C17_20020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C17_20025	COG0436	Aminotransferase
D9C17_20030	COG1850	ribulose-bisphosphate carboxylase activity
D9C17_20035	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9C17_20040	COG0235	Class ii aldolase
D9C17_20045	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9C17_20050	COG3339	Conserved Protein
D9C17_20065	COG3852	Histidine kinase
D9C17_20070	COG1846	Transcriptional regulator
D9C17_20075	COG1360	Flagellar Motor Protein
D9C17_20080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C17_20085	COG0542	response to heat
D9C17_20090	COG3949	Membrane
D9C17_20095	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9C17_20100	COG0720	synthase
D9C17_20105	COG0602	queuosine metabolic process
D9C17_20110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9C17_20120	COG4873	Protein conserved in bacteria
D9C17_20130	COG3773	Cell wall hydrolase
D9C17_20135	COG2244	polysaccharide biosynthetic process
D9C17_20140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_20145	COG2217	Heavy metal translocating P-type atpase
D9C17_20155	COG0006	proline dipeptidase activity
D9C17_20160	COG1609	Transcriptional regulator
D9C17_20165	COG3711	transcriptional antiterminator
D9C17_20170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C17_20170	COG1263	PTS System
D9C17_20170	COG2190	(PTS) system
D9C17_20175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_20180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9C17_20190	COG1533	DNA photolyase activity
D9C17_20195	COG0456	acetyltransferase
D9C17_20200	COG0840	transmembrane signaling receptor activity
D9C17_20205	COG2084	Dehydrogenase
D9C17_20210	COG3328	transposase activity
D9C17_20220	COG2340	Cysteine-rich secretory protein family
D9C17_20225	COG0768	penicillin binding
D9C17_20230	COG4191	Histidine kinase
D9C17_20235	COG0436	Aminotransferase
D9C17_20245	COG0784	Response regulator, receiver
D9C17_20245	COG0835	chemotaxis
D9C17_20255	COG2814	Major facilitator Superfamily
D9C17_20260	COG1376	ErfK ybiS ycfS ynhG family protein
D9C17_20265	COG1408	metallophosphoesterase
D9C17_20270	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_20275	COG2200	EAL domain
D9C17_20280	COG4703	Protein of unknown function (DUF1797)
D9C17_20285	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9C17_20295	COG0517	IMP dehydrogenase activity
D9C17_20300	COG0583	DNA-binding transcription factor activity
D9C17_20305	COG0716	FMN binding
D9C17_20315	COG0716	FMN binding
D9C17_20320	COG2171	N-acyltransferase activity
D9C17_20325	COG1473	amidohydrolase
D9C17_20335	COG0668	transmembrane transport
D9C17_20340	COG0450	alkyl hydroperoxide reductase
D9C17_20345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_20365	COG0746	molybdenum cofactor guanylyltransferase activity
D9C17_20370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C17_20375	COG0303	'Molybdopterin
D9C17_20380	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9C17_20385	COG0314	molybdopterin synthase activity
D9C17_20390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9C17_20400	COG1132	(ABC) transporter
D9C17_20410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C17_20415	COG1136	(ABC) transporter
D9C17_20420	COG0577	efflux transmembrane transporter activity
D9C17_20425	COG1349	DNA-binding transcription factor activity
D9C17_20430	COG1105	Belongs to the carbohydrate kinase PfkB family
D9C17_20435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C17_20435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C17_20435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C17_20440	COG0681	Belongs to the peptidase S26 family
D9C17_20450	COG0488	(ABC) transporter
D9C17_20455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C17_20460	COG2309	aminopeptidase activity
D9C17_20470	COG1077	Cell shape determining protein MreB Mrl
D9C17_20475	COG2002	toxin-antitoxin pair type II binding
D9C17_20480	COG3852	Histidine kinase
D9C17_20485	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9C17_20485	COG2105	PFAM AIG2 family protein
D9C17_20490	COG0569	domain protein
D9C17_20495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C17_20500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C17_20510	COG0561	phosphatase activity
D9C17_20515	COG0242	peptide deformylase activity
D9C17_20530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C17_20535	COG0022	dehydrogenase e1 component
D9C17_20540	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C17_20545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C17_20550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C17_20560	COG1982	Orn Lys Arg decarboxylase major
D9C17_20565	COG4476	Belongs to the UPF0223 family
D9C17_20570	COG4493	Belongs to the UPF0637 family
D9C17_20580	COG0483	inositol monophosphate 1-phosphatase activity
D9C17_20595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9C17_20650	COG4896	Protein conserved in bacteria
D9C17_20660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9C17_20665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C17_20670	COG2066	Belongs to the glutaminase family
D9C17_20675	COG4838	Belongs to the UPF0358 family
D9C17_20680	COG0772	Belongs to the SEDS family
D9C17_20685	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9C17_20690	COG1612	heme a metabolic process
D9C17_20695	COG0109	protoheme IX farnesyltransferase activity
D9C17_20700	COG2010	Cytochrome c
D9C17_20700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C17_20705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C17_20710	COG1845	cytochrome c oxidase, subunit III
D9C17_20715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C17_20720	COG3336	cytochrome c oxidase
D9C17_20730	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9C17_20735	COG2340	Cysteine-rich secretory protein family
D9C17_20750	COG3679	Belongs to the UPF0342 family
D9C17_20755	COG4471	UPF0298 protein
D9C17_20760	COG0742	ribosomal rna small subunit methyltransferase
D9C17_20765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9C17_20770	COG3314	Sporulation integral membrane protein YlbJ
D9C17_20775	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C17_20780	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9C17_20785	COG1323	Belongs to the UPF0348 family
D9C17_20795	COG1399	metal-binding, possibly nucleic acid-binding protein
D9C17_20800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9C17_20810	COG0454	-acetyltransferase
D9C17_20815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C17_20820	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9C17_20825	COG2001	Belongs to the MraZ family
D9C17_20830	COG0275	rRNA processing
D9C17_20835	COG4839	cell division protein FtsL
D9C17_20845	COG0768	penicillin binding
D9C17_20850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9C17_20855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C17_20860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C17_20865	COG0772	Belongs to the SEDS family
D9C17_20870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C17_20875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9C17_20880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9C17_20885	COG3879	Bacterial protein of unknown function (DUF881)
D9C17_20890	COG3879	Bacterial protein of unknown function (DUF881)
D9C17_20895	COG3856	small basic protein
D9C17_20900	COG0849	cell division
D9C17_20905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9C17_20910	COG1404	Belongs to the peptidase S8 family
D9C17_20910	COG4412	M6 family metalloprotease domain protein
D9C17_20920	COG1191	sigma factor activity
D9C17_20925	COG1191	sigma factor activity
D9C17_20930	COG1119	ATPase activity
D9C17_20935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C17_20940	COG1873	PFAM PRC-barrel domain
D9C17_20950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9C17_20955	COG1799	cell septum assembly
D9C17_20960	COG0762	integral membrane protein
D9C17_20965	COG2302	S4 RNA-binding domain
D9C17_20970	COG3599	regulation of cell shape
D9C17_20975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9C17_20985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9C17_20990	COG0564	pseudouridine synthase activity
D9C17_20995	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9C17_21000	COG2233	PERMEase
D9C17_21005	COG0540	Belongs to the ATCase OTCase family
D9C17_21010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C17_21015	COG0505	Belongs to the CarA family
D9C17_21020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C17_21025	COG0543	2 iron, 2 sulfur cluster binding
D9C17_21030	COG0167	dihydroorotate dehydrogenase activity
D9C17_21035	COG0284	orotidine-5'-phosphate decarboxylase activity
D9C17_21040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9C17_21045	COG0175	sulfate reduction
D9C17_21050	COG0306	phosphate transporter
D9C17_21055	COG2046	Belongs to the sulfate adenylyltransferase family
D9C17_21060	COG0529	Catalyzes the synthesis of activated sulfate
D9C17_21065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C17_21070	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9C17_21075	COG1648	precorrin-2 dehydrogenase activity
D9C17_21085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C17_21090	COG1561	YicC-like family, N-terminal region
D9C17_21095	COG2052	Domain of unknown function (DUF370)
D9C17_21100	COG0194	GDP metabolic process
D9C17_21105	COG1758	RNA polymerase activity
D9C17_21110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C17_21115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C17_21120	COG0242	peptide deformylase activity
D9C17_21125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9C17_21130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9C17_21130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C17_21135	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9C17_21140	COG0631	protein serine/threonine phosphatase activity
D9C17_21145	COG2815	serine threonine protein kinase
D9C17_21145	COG0515	serine threonine protein kinase
D9C17_21150	COG1162	GTPase activity
D9C17_21155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9C17_21160	COG1564	THIamine pyrophosphokinase
D9C17_21170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9C17_21175	COG1302	Protein conserved in bacteria
D9C17_21180	COG1461	Dihydroxyacetone kinase
D9C17_21185	COG1760	l-serine dehydratase
D9C17_21190	COG1760	l-serine dehydratase
D9C17_21195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9C17_21200	COG1349	DNA-binding transcription factor activity
D9C17_21200	COG2050	protein possibly involved in aromatic compounds catabolism
D9C17_21205	COG0416	fatty acid biosynthetic process
D9C17_21210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C17_21215	COG1028	Short-chain dehydrogenase reductase Sdr
D9C17_21220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C17_21225	COG0571	ribonuclease III activity
D9C17_21230	COG1196	nuclear chromosome segregation
D9C17_21235	COG0552	protein localization to endoplasmic reticulum
D9C17_21245	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9C17_21250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9C17_21255	COG0228	four-way junction DNA binding
D9C17_21260	COG1837	Belongs to the UPF0109 family
D9C17_21270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9C17_21275	COG0336	Belongs to the RNA methyltransferase TrmD family
D9C17_21280	COG0335	large ribosomal subunit rRNA binding
D9C17_21285	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C17_21290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C17_21300	COG2257	FlhB HrpN YscU SpaS Family
D9C17_21305	COG0045	succinate-CoA ligase (ADP-forming) activity
D9C17_21310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9C17_21315	COG0758	DNA mediated transformation
D9C17_21320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C17_21325	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9C17_21330	COG4974	Belongs to the 'phage' integrase family
D9C17_21335	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9C17_21340	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9C17_21345	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C17_21350	COG1815	bacterial-type flagellum-dependent cell motility
D9C17_21355	COG1558	bacterial-type flagellum-dependent cell motility
D9C17_21360	COG1677	Flagellar hook-basal body complex protein FliE
D9C17_21370	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C17_21375	COG1317	bacterial-type flagellum organization
D9C17_21380	COG1157	protein secretion by the type III secretion system
D9C17_21385	COG2882	bacterial-type flagellum organization
D9C17_21390	COG3334	PFAM MgtE intracellular
D9C17_21395	COG3144	bacterial-type flagellum assembly
D9C17_21400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9C17_21405	COG4786	Flagellar basal body rod
D9C17_21410	COG1582	Flagellar protein (FlbD)
D9C17_21415	COG1580	Controls the rotational direction of flagella during chemotaxis
D9C17_21420	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C17_21425	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C17_21425	COG1776	CheC inhibitor of MCP methylation
D9C17_21430	COG2201	protein-glutamate methylesterase activity
D9C17_21435	COG3190	flagellar
D9C17_21440	COG1338	Plays a role in the flagellum-specific transport system
D9C17_21445	COG1987	bacterial-type flagellum assembly
D9C17_21450	COG1684	flagellar biosynthetic protein fliR
D9C17_21455	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C17_21460	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C17_21465	COG1419	protein localization to endoplasmic reticulum
D9C17_21470	COG0455	bacterial-type flagellum organization
D9C17_21475	COG2201	protein-glutamate methylesterase activity
D9C17_21480	COG0643	Histidine kinase
D9C17_21480	COG2198	Histidine kinase
D9C17_21485	COG0835	chemotaxis
D9C17_21495	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9C17_21500	COG1191	sigma factor activity
D9C17_21510	COG0052	Belongs to the universal ribosomal protein uS2 family
D9C17_21515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9C17_21520	COG0528	UMP kinase activity
D9C17_21525	COG0233	cytoplasmic translational termination
D9C17_21530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9C17_21535	COG4589	Belongs to the CDS family
D9C17_21540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9C17_21545	COG0750	zinc metalloprotease
D9C17_21550	COG0442	prolyl-tRNA aminoacylation
D9C17_21555	COG2176	DNA-directed DNA polymerase activity
D9C17_21560	COG0779	Required for maturation of 30S ribosomal subunits
D9C17_21565	COG0195	Participates in both transcription termination and antitermination
D9C17_21570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9C17_21575	COG1358	cellular component organization or biogenesis
D9C17_21580	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9C17_21585	COG1550	Protein conserved in bacteria
D9C17_21590	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9C17_21595	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9C17_21600	COG0196	riboflavin kinase activity
D9C17_21605	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9C17_21610	COG1185	polyribonucleotide nucleotidyltransferase activity
D9C17_21615	COG0726	polysaccharide deacetylase
D9C17_21620	COG0612	Peptidase, M16
D9C17_21625	COG1873	PFAM PRC-barrel domain
D9C17_21630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C17_21635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C17_21640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9C17_21645	COG0527	aspartate kinase activity
D9C17_21650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C17_21655	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C17_21660	COG0740	serine-type endopeptidase activity
D9C17_21670	COG1674	ftsk spoiiie
D9C17_21670	COG4980	gas vesicle protein
D9C17_21675	COG2188	Transcriptional regulator
D9C17_21680	COG2814	Major facilitator Superfamily
D9C17_21685	COG0612	Peptidase, M16
D9C17_21690	COG0612	Peptidase, M16
D9C17_21695	COG0300	oxidoreductase activity
D9C17_21710	COG1426	Protein conserved in bacteria
D9C17_21715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9C17_21720	COG1058	Belongs to the CinA family
D9C17_21720	COG1546	Belongs to the CinA family
D9C17_21725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9C17_21730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C17_21735	COG1418	mRNA catabolic process
D9C17_21740	COG1692	metallophosphoesterase
D9C17_21745	COG2359	stage V sporulation protein S
D9C17_21750	COG1063	alcohol dehydrogenase
D9C17_21755	COG0156	8-amino-7-oxononanoate synthase activity
D9C17_21760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C17_21765	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9C17_21775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9C17_21780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9C17_21855	COG3328	transposase activity
D9C17_21875	COG3226	Transcriptional regulator
D9C17_21885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C17_21890	COG1404	Belongs to the peptidase S8 family
D9C17_21900	COG4195	phage-related replication protein
D9C17_21905	COG1764	response to oxidative stress
D9C17_21910	COG2076	Multidrug Resistance protein
D9C17_21915	COG2076	Multidrug Resistance protein
D9C17_21930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9C17_21935	COG1923	regulation of RNA biosynthetic process
D9C17_21950	COG1780	Probably involved in ribonucleotide reductase function
D9C17_21955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C17_21960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C17_21965	COG4112	unkown
D9C17_21970	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C17_21980	COG0464	growth
D9C17_21985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9C17_21990	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9C17_21995	COG0789	Transcriptional regulator
D9C17_22000	COG0174	glutamine synthetase
D9C17_22005	COG4974	Belongs to the 'phage' integrase family
D9C17_22025	COG3645	SOS response
D9C17_22025	COG3646	Phage regulatory protein
D9C17_22235	COG0791	NLP P60 protein
D9C17_22235	COG3883	PFAM NLP P60 protein
D9C17_22290	COG0629	single-stranded DNA binding
D9C17_22305	COG0582	viral genome integration into host DNA
D9C17_22335	COG1793	dna ligase
D9C17_22350	COG1525	nuclease
D9C17_22460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C17_22510	COG0457	Tetratricopeptide repeat