locus-tag	class	description
D9C18_00035	COG3832	glyoxalase III activity
D9C18_00050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C18_00095	COG0756	dUTP diphosphatase activity
D9C18_00110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C18_00115	COG2814	Major facilitator Superfamily
D9C18_00120	COG1525	nuclease
D9C18_00125	COG3328	transposase activity
D9C18_00140	COG1070	Carbohydrate kinase
D9C18_00145	COG2115	Belongs to the xylose isomerase family
D9C18_00150	COG1940	carbohydrate kinase activity
D9C18_00155	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C18_00170	COG2211	Major facilitator Superfamily
D9C18_00175	COG0135	phosphoribosylanthranilate isomerase activity
D9C18_00200	COG3655	Transcriptional regulator
D9C18_00215	COG3328	transposase activity
D9C18_00240	COG4282	regulation of fungal-type cell wall biogenesis
D9C18_00280	COG5444	nuclease activity
D9C18_00290	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C18_00290	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_00290	COG1388	LysM domain
D9C18_00335	COG3953	SLT domain
D9C18_00335	COG5412	phage tail tape measure protein
D9C18_00480	COG3645	SOS response
D9C18_00480	COG3646	Phage regulatory protein
D9C18_00500	COG4974	Belongs to the 'phage' integrase family
D9C18_00505	COG0174	glutamine synthetase
D9C18_00510	COG0789	Transcriptional regulator
D9C18_00515	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9C18_00520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9C18_00525	COG0464	growth
D9C18_00535	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C18_00540	COG4112	unkown
D9C18_00545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C18_00550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C18_00555	COG1780	Probably involved in ribonucleotide reductase function
D9C18_00570	COG1923	regulation of RNA biosynthetic process
D9C18_00575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9C18_00590	COG2076	Multidrug Resistance protein
D9C18_00595	COG2076	Multidrug Resistance protein
D9C18_00600	COG1764	response to oxidative stress
D9C18_00605	COG4195	phage-related replication protein
D9C18_00615	COG1404	Belongs to the peptidase S8 family
D9C18_00620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C18_00630	COG3226	Transcriptional regulator
D9C18_00650	COG3328	transposase activity
D9C18_00720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9C18_00725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9C18_00735	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9C18_00740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C18_00745	COG0156	8-amino-7-oxononanoate synthase activity
D9C18_00750	COG1063	alcohol dehydrogenase
D9C18_00755	COG2359	stage V sporulation protein S
D9C18_00760	COG1692	metallophosphoesterase
D9C18_00765	COG1418	mRNA catabolic process
D9C18_00770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C18_00775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9C18_00780	COG1546	Belongs to the CinA family
D9C18_00780	COG1058	Belongs to the CinA family
D9C18_00785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9C18_00790	COG1426	Protein conserved in bacteria
D9C18_00805	COG0300	oxidoreductase activity
D9C18_00810	COG0612	Peptidase, M16
D9C18_00815	COG0612	Peptidase, M16
D9C18_00820	COG2814	Major facilitator Superfamily
D9C18_00825	COG2188	Transcriptional regulator
D9C18_00830	COG1674	ftsk spoiiie
D9C18_00830	COG4980	gas vesicle protein
D9C18_00840	COG0740	serine-type endopeptidase activity
D9C18_00845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C18_00850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C18_00855	COG0527	aspartate kinase activity
D9C18_00860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9C18_00865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C18_00870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C18_00875	COG1873	PFAM PRC-barrel domain
D9C18_00880	COG0612	Peptidase, M16
D9C18_00885	COG0726	polysaccharide deacetylase
D9C18_00890	COG1185	polyribonucleotide nucleotidyltransferase activity
D9C18_00895	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9C18_00900	COG0196	riboflavin kinase activity
D9C18_00905	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9C18_00910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9C18_00915	COG1550	Protein conserved in bacteria
D9C18_00920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9C18_00925	COG1358	cellular component organization or biogenesis
D9C18_00930	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9C18_00935	COG0195	Participates in both transcription termination and antitermination
D9C18_00940	COG0779	Required for maturation of 30S ribosomal subunits
D9C18_00945	COG2176	DNA-directed DNA polymerase activity
D9C18_00950	COG0442	prolyl-tRNA aminoacylation
D9C18_00955	COG0750	zinc metalloprotease
D9C18_00960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9C18_00965	COG4589	Belongs to the CDS family
D9C18_00970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9C18_00975	COG0233	cytoplasmic translational termination
D9C18_00980	COG0528	UMP kinase activity
D9C18_00985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9C18_00990	COG0052	Belongs to the universal ribosomal protein uS2 family
D9C18_01000	COG1191	sigma factor activity
D9C18_01005	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9C18_01015	COG0835	chemotaxis
D9C18_01020	COG2198	Histidine kinase
D9C18_01020	COG0643	Histidine kinase
D9C18_01025	COG2201	protein-glutamate methylesterase activity
D9C18_01030	COG0455	bacterial-type flagellum organization
D9C18_01035	COG1419	protein localization to endoplasmic reticulum
D9C18_01040	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C18_01045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C18_01050	COG1684	flagellar biosynthetic protein fliR
D9C18_01055	COG1987	bacterial-type flagellum assembly
D9C18_01060	COG1338	Plays a role in the flagellum-specific transport system
D9C18_01065	COG3190	flagellar
D9C18_01070	COG2201	protein-glutamate methylesterase activity
D9C18_01075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C18_01075	COG1776	CheC inhibitor of MCP methylation
D9C18_01080	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C18_01085	COG1580	Controls the rotational direction of flagella during chemotaxis
D9C18_01090	COG1582	Flagellar protein (FlbD)
D9C18_01095	COG4786	Flagellar basal body rod
D9C18_01100	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9C18_01105	COG3144	bacterial-type flagellum assembly
D9C18_01110	COG3334	PFAM MgtE intracellular
D9C18_01115	COG2882	bacterial-type flagellum organization
D9C18_01120	COG1157	protein secretion by the type III secretion system
D9C18_01125	COG1317	bacterial-type flagellum organization
D9C18_01130	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C18_01140	COG1677	Flagellar hook-basal body complex protein FliE
D9C18_01145	COG1558	bacterial-type flagellum-dependent cell motility
D9C18_01150	COG1815	bacterial-type flagellum-dependent cell motility
D9C18_01155	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C18_01160	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9C18_01165	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9C18_01170	COG4974	Belongs to the 'phage' integrase family
D9C18_01175	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9C18_01180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C18_01185	COG0758	DNA mediated transformation
D9C18_01190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9C18_01195	COG0045	succinate-CoA ligase (ADP-forming) activity
D9C18_01200	COG2257	FlhB HrpN YscU SpaS Family
D9C18_01215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C18_01220	COG0335	large ribosomal subunit rRNA binding
D9C18_01225	COG0336	Belongs to the RNA methyltransferase TrmD family
D9C18_01230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9C18_01240	COG1837	Belongs to the UPF0109 family
D9C18_01245	COG0228	four-way junction DNA binding
D9C18_01250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9C18_01255	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9C18_01265	COG0552	protein localization to endoplasmic reticulum
D9C18_01270	COG1196	nuclear chromosome segregation
D9C18_01275	COG0571	ribonuclease III activity
D9C18_01280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C18_01285	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_01290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C18_01295	COG0416	fatty acid biosynthetic process
D9C18_01300	COG1349	DNA-binding transcription factor activity
D9C18_01300	COG2050	protein possibly involved in aromatic compounds catabolism
D9C18_01305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9C18_01310	COG1760	l-serine dehydratase
D9C18_01315	COG1760	l-serine dehydratase
D9C18_01320	COG1461	Dihydroxyacetone kinase
D9C18_01325	COG1302	Protein conserved in bacteria
D9C18_01330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9C18_01340	COG1564	THIamine pyrophosphokinase
D9C18_01345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9C18_01350	COG1162	GTPase activity
D9C18_01355	COG0515	serine threonine protein kinase
D9C18_01355	COG2815	serine threonine protein kinase
D9C18_01360	COG0631	protein serine/threonine phosphatase activity
D9C18_01365	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9C18_01370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9C18_01370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C18_01375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9C18_01380	COG0242	peptide deformylase activity
D9C18_01385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C18_01390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C18_01395	COG1758	RNA polymerase activity
D9C18_01400	COG0194	GDP metabolic process
D9C18_01405	COG2052	Domain of unknown function (DUF370)
D9C18_01410	COG1561	YicC-like family, N-terminal region
D9C18_01415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C18_01425	COG1648	precorrin-2 dehydrogenase activity
D9C18_01430	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9C18_01435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C18_01440	COG0529	Catalyzes the synthesis of activated sulfate
D9C18_01445	COG2046	Belongs to the sulfate adenylyltransferase family
D9C18_01450	COG0306	phosphate transporter
D9C18_01455	COG0175	sulfate reduction
D9C18_01460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9C18_01465	COG0284	orotidine-5'-phosphate decarboxylase activity
D9C18_01470	COG0167	dihydroorotate dehydrogenase activity
D9C18_01475	COG0543	2 iron, 2 sulfur cluster binding
D9C18_01480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C18_01485	COG0505	Belongs to the CarA family
D9C18_01490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C18_01495	COG0540	Belongs to the ATCase OTCase family
D9C18_01500	COG2233	PERMEase
D9C18_01505	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9C18_01510	COG0564	pseudouridine synthase activity
D9C18_01515	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9C18_01520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C18_01525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9C18_01530	COG3599	regulation of cell shape
D9C18_01535	COG2302	S4 RNA-binding domain
D9C18_01540	COG0762	integral membrane protein
D9C18_01545	COG1799	cell septum assembly
D9C18_01550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9C18_01560	COG1873	PFAM PRC-barrel domain
D9C18_01565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C18_01570	COG1119	ATPase activity
D9C18_01575	COG1191	sigma factor activity
D9C18_01580	COG1191	sigma factor activity
D9C18_01590	COG1404	Belongs to the peptidase S8 family
D9C18_01590	COG4412	M6 family metalloprotease domain protein
D9C18_01595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9C18_01600	COG0849	cell division
D9C18_01605	COG3856	small basic protein
D9C18_01610	COG3879	Bacterial protein of unknown function (DUF881)
D9C18_01615	COG3879	Bacterial protein of unknown function (DUF881)
D9C18_01620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9C18_01625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9C18_01630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C18_01635	COG0772	Belongs to the SEDS family
D9C18_01640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C18_01645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C18_01650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9C18_01655	COG0768	penicillin binding
D9C18_01665	COG4839	cell division protein FtsL
D9C18_01670	COG0275	rRNA processing
D9C18_01675	COG2001	Belongs to the MraZ family
D9C18_01680	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9C18_01685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C18_01690	COG0454	-acetyltransferase
D9C18_01700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9C18_01705	COG1399	metal-binding, possibly nucleic acid-binding protein
D9C18_01715	COG1323	Belongs to the UPF0348 family
D9C18_01720	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9C18_01725	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C18_01730	COG3314	Sporulation integral membrane protein YlbJ
D9C18_01735	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9C18_01740	COG0742	ribosomal rna small subunit methyltransferase
D9C18_01745	COG4471	UPF0298 protein
D9C18_01750	COG3679	Belongs to the UPF0342 family
D9C18_01765	COG2340	Cysteine-rich secretory protein family
D9C18_01770	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9C18_01780	COG3336	cytochrome c oxidase
D9C18_01785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C18_01790	COG1845	cytochrome c oxidase, subunit III
D9C18_01795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C18_01800	COG2010	Cytochrome c
D9C18_01800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C18_01805	COG0109	protoheme IX farnesyltransferase activity
D9C18_01810	COG1612	heme a metabolic process
D9C18_01815	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9C18_01820	COG0772	Belongs to the SEDS family
D9C18_01825	COG4838	Belongs to the UPF0358 family
D9C18_01835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C18_01840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9C18_01850	COG4896	Protein conserved in bacteria
D9C18_01905	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9C18_01920	COG0483	inositol monophosphate 1-phosphatase activity
D9C18_01930	COG4493	Belongs to the UPF0637 family
D9C18_01935	COG4476	Belongs to the UPF0223 family
D9C18_01940	COG1982	Orn Lys Arg decarboxylase major
D9C18_01950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_01955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C18_01960	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C18_01965	COG0022	dehydrogenase e1 component
D9C18_01970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C18_01985	COG0242	peptide deformylase activity
D9C18_01990	COG0561	phosphatase activity
D9C18_02000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C18_02005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C18_02010	COG0569	domain protein
D9C18_02015	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9C18_02015	COG2105	PFAM AIG2 family protein
D9C18_02020	COG3852	Histidine kinase
D9C18_02025	COG2002	toxin-antitoxin pair type II binding
D9C18_02030	COG1077	Cell shape determining protein MreB Mrl
D9C18_02040	COG2309	aminopeptidase activity
D9C18_02045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C18_02050	COG0488	(ABC) transporter
D9C18_02060	COG0681	Belongs to the peptidase S26 family
D9C18_02065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C18_02065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C18_02065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_02070	COG1105	Belongs to the carbohydrate kinase PfkB family
D9C18_02075	COG1349	DNA-binding transcription factor activity
D9C18_02080	COG0577	efflux transmembrane transporter activity
D9C18_02085	COG1136	(ABC) transporter
D9C18_02090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C18_02100	COG1132	(ABC) transporter
D9C18_02110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9C18_02115	COG0314	molybdopterin synthase activity
D9C18_02120	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9C18_02125	COG0303	'Molybdopterin
D9C18_02130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C18_02135	COG0746	molybdenum cofactor guanylyltransferase activity
D9C18_02155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_02160	COG0450	alkyl hydroperoxide reductase
D9C18_02165	COG0668	transmembrane transport
D9C18_02175	COG1473	amidohydrolase
D9C18_02180	COG2171	N-acyltransferase activity
D9C18_02185	COG0716	FMN binding
D9C18_02195	COG0716	FMN binding
D9C18_02200	COG0583	DNA-binding transcription factor activity
D9C18_02205	COG0517	IMP dehydrogenase activity
D9C18_02215	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9C18_02220	COG4703	Protein of unknown function (DUF1797)
D9C18_02225	COG2200	EAL domain
D9C18_02230	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_02235	COG1408	metallophosphoesterase
D9C18_02240	COG1376	ErfK ybiS ycfS ynhG family protein
D9C18_02245	COG2814	Major facilitator Superfamily
D9C18_02255	COG0784	Response regulator, receiver
D9C18_02255	COG0835	chemotaxis
D9C18_02265	COG0436	Aminotransferase
D9C18_02270	COG4191	Histidine kinase
D9C18_02275	COG0768	penicillin binding
D9C18_02280	COG2340	Cysteine-rich secretory protein family
D9C18_02290	COG3328	transposase activity
D9C18_02295	COG2084	Dehydrogenase
D9C18_02300	COG0840	transmembrane signaling receptor activity
D9C18_02305	COG0456	acetyltransferase
D9C18_02310	COG1533	DNA photolyase activity
D9C18_02320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9C18_02325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_02330	COG2190	(PTS) system
D9C18_02330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_02330	COG1263	PTS System
D9C18_02335	COG3711	transcriptional antiterminator
D9C18_02340	COG1609	Transcriptional regulator
D9C18_02345	COG0006	proline dipeptidase activity
D9C18_02355	COG2217	Heavy metal translocating P-type atpase
D9C18_02360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_02365	COG2244	polysaccharide biosynthetic process
D9C18_02370	COG3773	Cell wall hydrolase
D9C18_02380	COG4873	Protein conserved in bacteria
D9C18_02390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9C18_02395	COG0602	queuosine metabolic process
D9C18_02400	COG0720	synthase
D9C18_02405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9C18_02410	COG3949	Membrane
D9C18_02415	COG0542	response to heat
D9C18_02420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C18_02425	COG1360	Flagellar Motor Protein
D9C18_02430	COG1846	Transcriptional regulator
D9C18_02435	COG3852	Histidine kinase
D9C18_02450	COG3339	Conserved Protein
D9C18_02455	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9C18_02460	COG0235	Class ii aldolase
D9C18_02465	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9C18_02470	COG1850	ribulose-bisphosphate carboxylase activity
D9C18_02475	COG0436	Aminotransferase
D9C18_02480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C18_02485	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9C18_02490	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9C18_02500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C18_02505	COG5002	protein histidine kinase activity
D9C18_02510	COG3594	Acyltransferase
D9C18_02530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C18_02535	COG0501	Belongs to the peptidase M48B family
D9C18_02555	COG1191	sigma factor activity
D9C18_02560	COG0861	Integral membrane protein TerC family
D9C18_02565	COG0586	Pfam SNARE associated Golgi protein
D9C18_02570	COG5001	Diguanylate cyclase
D9C18_02570	COG3300	MHYT domain
D9C18_02575	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9C18_02580	COG3285	dna ligase
D9C18_02580	COG1793	dna ligase
D9C18_02585	COG0463	Glycosyl transferase, family 2
D9C18_02595	COG1408	metallophosphoesterase
D9C18_02600	COG0726	polysaccharide deacetylase
D9C18_02605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C18_02610	COG1846	Transcriptional regulator
D9C18_02625	COG0789	Transcriptional regulator
D9C18_02630	COG2239	Acts as a magnesium transporter
D9C18_02645	COG3212	peptidase
D9C18_02650	COG3212	peptidase
D9C18_02655	COG5002	protein histidine kinase activity
D9C18_02655	COG3850	Histidine kinase
D9C18_02660	COG0745	RESPONSE REGULATOR receiver
D9C18_02670	COG4721	ABC-type cobalt transport system, permease component
D9C18_02675	COG1122	ATPase activity
D9C18_02680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C18_02685	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_02690	COG1404	Belongs to the peptidase S8 family
D9C18_02695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C18_02705	COG0590	tRNA wobble adenosine to inosine editing
D9C18_02715	COG1764	response to oxidative stress
D9C18_02720	COG1846	Transcriptional regulator
D9C18_02725	COG1764	response to oxidative stress
D9C18_02730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9C18_02735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C18_02740	COG0788	formyltetrahydrofolate deformylase activity
D9C18_02745	COG2076	Multidrug Resistance protein
D9C18_02750	COG2076	Multidrug Resistance protein
D9C18_02755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_02760	COG2318	DinB family
D9C18_02765	COG2323	membrane
D9C18_02775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9C18_02775	COG1017	nitric oxide dioxygenase activity
D9C18_02780	COG1607	acyl-coa hydrolase
D9C18_02790	COG2706	6-phosphogluconolactonase activity
D9C18_02795	COG4608	Belongs to the ABC transporter superfamily
D9C18_02800	COG0791	NLP P60 protein
D9C18_02805	COG4948	Mandelate Racemase Muconate Lactonizing
D9C18_02810	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C18_02815	COG4166	transmembrane transport
D9C18_02820	COG0444	Belongs to the ABC transporter superfamily
D9C18_02825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C18_02830	COG0601	transmembrane transport
D9C18_02835	COG2362	D-Aminopeptidase
D9C18_02840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C18_02845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C18_02850	COG0463	Glycosyl transferase, family 2
D9C18_02855	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C18_02860	COG0346	lactoylglutathione lyase activity
D9C18_02865	COG0531	amino acid
D9C18_02870	COG1392	Phosphate transport regulator
D9C18_02875	COG0306	phosphate transporter
D9C18_02895	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_02895	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C18_02935	COG3778	Protein conserved in bacteria
D9C18_02940	COG3299	homolog of phage Mu protein gp47
D9C18_02945	COG3628	GPW Gp25 family protein
D9C18_02955	COG4193	domain, Protein
D9C18_02960	COG1652	LysM domain
D9C18_02965	COG3953	SLT domain
D9C18_02965	COG3953	SLT domain
D9C18_02965	COG5412	phage tail tape measure protein
D9C18_02965	COG5412	phage tail tape measure protein
D9C18_02965	COG5412	phage tail tape measure protein
D9C18_02965	COG3953	SLT domain
D9C18_03015	COG4653	Phage capsid family
D9C18_03020	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9C18_03025	COG5518	Phage portal protein
D9C18_03030	COG1783	phage Terminase large subunit
D9C18_03035	COG3728	DNA packaging
D9C18_03035	COG5484	DNA packaging
D9C18_03040	COG1595	DNA-templated transcription, initiation
D9C18_03060	COG1484	DNA-dependent DNA replication
D9C18_03065	COG1522	sequence-specific DNA binding
D9C18_03075	COG1396	sequence-specific DNA binding
D9C18_03080	COG2856	Zn peptidase
D9C18_03090	COG4195	phage-related replication protein
D9C18_03100	COG1388	LysM domain
D9C18_03100	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_03100	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C18_03115	COG0457	Tetratricopeptide repeat
D9C18_03135	COG2318	DinB family
D9C18_03140	COG0730	response to heat
D9C18_03145	COG2721	sulfolactate sulfo-lyase activity
D9C18_03150	COG0246	Mannitol dehydrogenase
D9C18_03155	COG1609	Transcriptional regulator
D9C18_03160	COG2271	Major facilitator Superfamily
D9C18_03165	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_03170	COG1312	Catalyzes the dehydration of D-mannonate
D9C18_03175	COG1063	alcohol dehydrogenase
D9C18_03180	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9C18_03185	COG2211	Major facilitator Superfamily
D9C18_03190	COG1904	glucuronate isomerase
D9C18_03195	COG1252	NADH dehydrogenase
D9C18_03210	COG0697	spore germination
D9C18_03215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C18_03220	COG0390	transport system, permease component
D9C18_03225	COG1587	Uroporphyrinogen-III synthase
D9C18_03235	COG1819	glycosyl
D9C18_03240	COG2124	cytochrome p450
D9C18_03250	COG1051	belongs to the nudix hydrolase family
D9C18_03260	COG2427	Protein of unknown function (DUF1641)
D9C18_03275	COG2205	protein histidine kinase activity
D9C18_03280	COG5504	Zn-dependent protease
D9C18_03295	COG0726	polysaccharide deacetylase
D9C18_03305	COG0109	protoheme IX farnesyltransferase activity
D9C18_03325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C18_03335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_03340	COG3328	transposase activity
D9C18_03355	COG1482	cell wall glycoprotein biosynthetic process
D9C18_03360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C18_03360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C18_03360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_03365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_03365	COG3711	transcriptional antiterminator
D9C18_03375	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C18_03435	COG3328	transposase activity
D9C18_03450	COG5444	nuclease activity
D9C18_03455	COG0457	Tetratricopeptide repeat
D9C18_03520	COG1396	sequence-specific DNA binding
D9C18_03555	COG5505	Protein of unknown function (DUF819)
D9C18_03560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_03565	COG0626	cystathionine gamma-synthase activity
D9C18_03570	COG0626	cystathionine gamma-synthase activity
D9C18_03575	COG2382	esterase
D9C18_03580	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C18_03585	COG2153	protein acetylation
D9C18_03595	COG0210	DNA helicase
D9C18_03650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9C18_03655	COG0351	phosphomethylpyrimidine kinase
D9C18_03660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C18_03665	COG2022	thiamine diphosphate biosynthetic process
D9C18_03670	COG2104	thiamine diphosphate biosynthetic process
D9C18_03675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C18_03680	COG0352	thiamine-phosphate diphosphorylase activity
D9C18_03685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9C18_03690	COG0475	glutathione-regulated potassium exporter activity
D9C18_03690	COG0569	domain protein
D9C18_03695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9C18_03700	COG0564	pseudouridine synthase activity
D9C18_03705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C18_03710	COG2357	RelA SpoT domain protein
D9C18_03720	COG4116	CYTH
D9C18_03725	COG0741	lytic transglycosylase activity
D9C18_03730	COG2346	COG2346, Truncated hemoglobins
D9C18_03750	COG1164	Oligoendopeptidase f
D9C18_03755	COG4469	Competence protein
D9C18_03765	COG4862	establishment of competence for transformation
D9C18_03775	COG0861	Integral membrane protein TerC family
D9C18_03780	COG1393	Belongs to the ArsC family
D9C18_03785	COG0456	acetyltransferase
D9C18_03790	COG2814	Major facilitator Superfamily
D9C18_03795	COG4608	Belongs to the ABC transporter superfamily
D9C18_03800	COG0444	Belongs to the ABC transporter superfamily
D9C18_03805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C18_03810	COG0601	transmembrane transport
D9C18_03815	COG4166	transmembrane transport
D9C18_03820	COG0180	Tryptophanyl-tRNA synthetase
D9C18_03830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C18_03835	COG0601	transmembrane transport
D9C18_03845	COG4608	Belongs to the ABC transporter superfamily
D9C18_03850	COG0444	Belongs to the ABC transporter superfamily
D9C18_03855	COG5504	Zn-dependent protease
D9C18_03860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C18_03865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C18_03880	COG1744	ABC transporter substrate-binding protein PnrA-like
D9C18_03890	COG2267	carboxylic ester hydrolase activity
D9C18_03910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9C18_03915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C18_03920	COG0505	Belongs to the CarA family
D9C18_03925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C18_03940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9C18_03960	COG2151	metal-sulfur cluster biosynthetic enzyme
D9C18_03965	COG1073	alpha beta
D9C18_03970	COG0561	phosphatase activity
D9C18_03985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C18_03990	COG1307	EDD domain protein, DegV family
D9C18_04000	COG2996	Protein conserved in bacteria
D9C18_04005	COG1666	GTP binding
D9C18_04010	COG0646	methionine synthase
D9C18_04010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9C18_04015	COG2153	protein acetylation
D9C18_04025	COG2267	carboxylic ester hydrolase activity
D9C18_04030	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C18_04035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C18_04040	COG1279	arginine transmembrane transporter activity
D9C18_04045	COG2318	DinB family
D9C18_04050	COG0673	inositol 2-dehydrogenase activity
D9C18_04055	COG1609	Transcriptional regulator
D9C18_04060	COG1917	Cupin 2, conserved barrel domain protein
D9C18_04060	COG2207	Transcriptional regulator
D9C18_04065	COG0534	Mate efflux family protein
D9C18_04070	COG1562	ergosterol biosynthetic process
D9C18_04075	COG0367	asparagine synthase
D9C18_04085	COG1404	Belongs to the peptidase S8 family
D9C18_04095	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9C18_04100	COG5337	Spore coat protein CotH
D9C18_04140	COG1403	HNH endonuclease
D9C18_04145	COG0419	ATPase involved in DNA repair
D9C18_04150	COG0420	3'-5' exonuclease activity
D9C18_04155	COG1074	ATP-dependent DNA helicase activity
D9C18_04160	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9C18_04165	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9C18_04185	COG4533	DNA binding
D9C18_04190	COG2814	Major facilitator Superfamily
D9C18_04190	COG0477	Major facilitator Superfamily
D9C18_04195	COG3180	Ammonia monooxygenase
D9C18_04200	COG1609	Transcriptional regulator
D9C18_04205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C18_04210	COG0561	phosphatase activity
D9C18_04215	COG0673	inositol 2-dehydrogenase activity
D9C18_04220	COG0738	Major facilitator superfamily
D9C18_04235	COG1846	Transcriptional regulator
D9C18_04240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C18_04245	COG0681	Belongs to the peptidase S26 family
D9C18_04250	COG0398	Pfam SNARE associated Golgi protein
D9C18_04265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C18_04275	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_04280	COG4903	ComK protein
D9C18_04290	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_04300	COG0840	transmembrane signaling receptor activity
D9C18_04305	COG1268	BioY protein
D9C18_04310	COG0318	PFAM AMP-dependent synthetase and ligase
D9C18_04315	COG0183	Belongs to the thiolase family
D9C18_04320	COG0406	alpha-ribazole phosphatase activity
D9C18_04325	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C18_04330	COG0604	alcohol dehydrogenase
D9C18_04335	COG0456	acetyltransferase
D9C18_04345	COG0501	Belongs to the peptidase M48B family
D9C18_04355	COG0318	PFAM AMP-dependent synthetase and ligase
D9C18_04360	COG0702	epimerase
D9C18_04365	COG0095	Lipoate-protein ligase
D9C18_04370	COG1234	tRNA 3'-trailer cleavage
D9C18_04380	COG1301	dicarboxylic acid transport
D9C18_04385	COG4405	Protein conserved in bacteria
D9C18_04390	COG1363	Peptidase, m42
D9C18_04400	COG4377	Putative membrane peptidase family (DUF2324)
D9C18_04405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C18_04410	COG1511	domain protein
D9C18_04415	COG1309	transcriptional regulator
D9C18_04430	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9C18_04435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C18_04440	COG2329	Antibiotic biosynthesis monooxygenase
D9C18_04450	COG3069	C4-dicarboxylate transmembrane transporter activity
D9C18_04455	COG1473	amidohydrolase
D9C18_04465	COG4473	ABC transporter
D9C18_04470	COG1131	(ABC) transporter
D9C18_04475	COG0537	adenosine 5'-monophosphoramidase activity
D9C18_04480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9C18_04495	COG4980	gas vesicle protein
D9C18_04500	COG1846	Transcriptional regulator
D9C18_04530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C18_04540	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9C18_04545	COG4717	serine-type aminopeptidase activity
D9C18_04550	COG0420	3'-5' exonuclease activity
D9C18_04555	COG1668	transmembrane transport
D9C18_04560	COG4152	abc transporter atp-binding protein
D9C18_04570	COG1024	Enoyl-CoA hydratase
D9C18_04580	COG0490	domain, Protein
D9C18_04585	COG0475	glutathione-regulated potassium exporter activity
D9C18_04590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C18_04595	COG0561	phosphatase activity
D9C18_04605	COG3679	Belongs to the UPF0342 family
D9C18_04610	COG4399	Belongs to the UPF0754 family
D9C18_04615	COG0189	ligase activity
D9C18_04620	COG0189	ligase activity
D9C18_04645	COG0702	epimerase
D9C18_04650	COG1132	(ABC) transporter
D9C18_04655	COG1132	(ABC) transporter
D9C18_04665	COG0589	response to stress
D9C18_04670	COG1757	Na H antiporter
D9C18_04675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C18_04680	COG0726	polysaccharide deacetylase
D9C18_04685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9C18_04690	COG0668	transmembrane transport
D9C18_04700	COG0584	glycerophosphoryl diester phosphodiesterase
D9C18_04705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C18_04710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C18_04715	COG1253	flavin adenine dinucleotide binding
D9C18_04725	COG0789	Transcriptional regulator
D9C18_04730	COG1253	flavin adenine dinucleotide binding
D9C18_04735	COG0204	Acyl-transferase
D9C18_04740	COG0667	Aldo Keto reductase
D9C18_04745	COG1595	DNA-templated transcription, initiation
D9C18_04760	COG0456	acetyltransferase
D9C18_04765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C18_04770	COG0733	neurotransmitter:sodium symporter activity
D9C18_04775	COG0531	amino acid
D9C18_04780	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_04785	COG0372	Belongs to the citrate synthase family
D9C18_04790	COG0583	DNA-binding transcription factor activity
D9C18_04795	COG0791	NLP P60 protein
D9C18_04795	COG1388	LysM domain
D9C18_04800	COG1785	Belongs to the alkaline phosphatase family
D9C18_04805	COG2719	SpoVR family
D9C18_04810	COG0668	transmembrane transport
D9C18_04815	COG1959	2 iron, 2 sulfur cluster binding
D9C18_04820	COG1388	LysM domain
D9C18_04820	COG0791	NLP P60 protein
D9C18_04835	COG0431	NADPH-dependent FMN reductase
D9C18_04840	COG2197	response regulator
D9C18_04845	COG2203	Gaf domain
D9C18_04845	COG4585	Histidine kinase
D9C18_04850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C18_04855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9C18_04860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9C18_04865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9C18_04870	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9C18_04875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C18_04880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C18_04880	COG3153	acetyltransferase
D9C18_04885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C18_04890	COG0517	IMP dehydrogenase activity
D9C18_04900	COG0564	pseudouridine synthase activity
D9C18_04905	COG3764	Sortase (surface protein transpeptidase)
D9C18_04910	COG0737	Belongs to the 5'-nucleotidase family
D9C18_04910	COG4085	toxin activity
D9C18_04910	COG1525	nuclease
D9C18_04935	COG0457	Tetratricopeptide repeat
D9C18_04955	COG0741	lytic transglycosylase activity
D9C18_04955	COG0791	NLP P60 protein
D9C18_04960	COG5644	endopeptidase inhibitor activity
D9C18_05010	COG2946	Replication initiation factor
D9C18_05015	COG0582	viral genome integration into host DNA
D9C18_05040	COG5444	nuclease activity
D9C18_05045	COG1823	symporter activity
D9C18_05050	COG3706	GGDEF domain
D9C18_05055	COG1464	Belongs to the NlpA lipoprotein family
D9C18_05065	COG1278	Cold shock
D9C18_05070	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C18_05075	COG1131	(ABC) transporter
D9C18_05080	COG1131	(ABC) transporter
D9C18_05085	COG1725	Transcriptional regulator
D9C18_05105	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C18_05110	COG2814	Major facilitator Superfamily
D9C18_05115	COG1566	PFAM secretion protein HlyD family protein
D9C18_05120	COG1846	Transcriptional regulator
D9C18_05125	COG2718	Belongs to the UPF0229 family
D9C18_05130	COG2766	serine protein kinase
D9C18_05135	COG1664	Polymer-forming cytoskeletal
D9C18_05140	COG1664	Polymer-forming cytoskeletal
D9C18_05145	COG0789	Transcriptional regulator
D9C18_05150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9C18_05160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9C18_05165	COG3382	B3 4 domain protein
D9C18_05175	COG1476	TRANSCRIPTIONal
D9C18_05185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9C18_05195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C18_05200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C18_05205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C18_05210	COG1116	anion transmembrane transporter activity
D9C18_05215	COG0753	catalase activity
D9C18_05230	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9C18_05235	COG3340	Belongs to the peptidase S51 family
D9C18_05240	COG5577	PFAM Coat F domain
D9C18_05250	COG4326	sporulation control protein
D9C18_05360	COG0735	belongs to the Fur family
D9C18_05365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9C18_05370	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C18_05375	COG4129	membrane
D9C18_05380	COG1132	(ABC) transporter
D9C18_05385	COG3557	Belongs to the UPF0374 family
D9C18_05400	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_05410	COG1194	a g-specific adenine glycosylase
D9C18_05415	COG1988	membrane-bound metal-dependent
D9C18_05420	COG4485	Bacterial membrane protein, YfhO
D9C18_05425	COG0463	Glycosyl transferase, family 2
D9C18_05430	COG0596	Alpha beta hydrolase
D9C18_05435	COG5658	integral membrane protein
D9C18_05440	COG3103	Sh3 type 3 domain protein
D9C18_05455	COG2814	Major facilitator Superfamily
D9C18_05465	COG2137	regulation of response to DNA damage stimulus
D9C18_05470	COG1090	epimerase
D9C18_05485	COG0778	Nitroreductase
D9C18_05490	COG0384	phenazine biosynthesis protein PhzF
D9C18_05495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_05500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_05505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C18_05510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9C18_05510	COG0392	lysyltransferase activity
D9C18_05515	COG1846	Transcriptional regulator
D9C18_05525	COG2318	DinB family
D9C18_05530	COG2814	Major facilitator Superfamily
D9C18_05535	COG1309	transcriptional regulator
D9C18_05540	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9C18_05545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C18_05550	COG1695	Transcriptional regulator
D9C18_05555	COG0842	Transport permease protein
D9C18_05560	COG0842	Transport permease protein
D9C18_05560	COG1511	domain protein
D9C18_05565	COG1131	(ABC) transporter
D9C18_05570	COG2197	response regulator
D9C18_05575	COG4585	Histidine kinase
D9C18_05585	COG1082	Xylose isomerase domain protein TIM barrel
D9C18_05590	COG2814	Major facilitator Superfamily
D9C18_05595	COG1917	Cupin 2, conserved barrel domain protein
D9C18_05595	COG4977	sequence-specific DNA binding
D9C18_05600	COG2514	catechol 2,3-dioxygenase activity
D9C18_05605	COG2259	Doxx family
D9C18_05610	COG1132	(ABC) transporter
D9C18_05615	COG1132	(ABC) transporter
D9C18_05620	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C18_05625	COG1263	PTS System
D9C18_05625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_05630	COG1737	Transcriptional regulator
D9C18_05635	COG1486	melibiose metabolic process
D9C18_05640	COG4842	Belongs to the WXG100 family
D9C18_05665	COG1742	UPF0060 membrane protein
D9C18_05675	COG3284	Transcriptional regulator
D9C18_05680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C18_05685	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C18_05690	COG0022	dehydrogenase e1 component
D9C18_05695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C18_05705	COG4637	Psort location Cytoplasmic, score
D9C18_05720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C18_05725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C18_05730	COG0598	Magnesium transport protein CorA
D9C18_05735	COG2084	Dehydrogenase
D9C18_05740	COG0726	polysaccharide deacetylase
D9C18_05750	COG0535	radical SAM domain protein
D9C18_05755	COG0668	transmembrane transport
D9C18_05765	COG0387	Pfam Sodium calcium exchanger
D9C18_05770	COG0477	Major facilitator Superfamily
D9C18_05775	COG1295	ribonuclease BN
D9C18_05780	COG4980	gas vesicle protein
D9C18_05785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C18_05790	COG4840	Belongs to the UPF0435 family
D9C18_05795	COG2814	Major facilitator Superfamily
D9C18_05805	COG0693	protein deglycase activity
D9C18_05810	COG0737	Belongs to the 5'-nucleotidase family
D9C18_05815	COG0778	Nitroreductase
D9C18_05820	COG2188	Transcriptional regulator
D9C18_05825	COG0366	Alpha amylase catalytic
D9C18_05830	COG1263	PTS System
D9C18_05830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_05835	COG0697	spore germination
D9C18_05850	COG1115	amino acid carrier protein
D9C18_05865	COG1368	sulfuric ester hydrolase activity
D9C18_05870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_05870	COG1263	PTS System
D9C18_05875	COG0024	Methionine aminopeptidase
D9C18_05895	COG2258	MOSC domain
D9C18_05900	COG1254	Belongs to the acylphosphatase family
D9C18_05905	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9C18_05910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C18_05915	COG2851	Citrate transporter
D9C18_05920	COG3181	Tripartite tricarboxylate transporter family receptor
D9C18_05925	COG4565	transcriptional regulatory protein
D9C18_05930	COG3290	protein histidine kinase activity
D9C18_05935	COG0471	metal ion transport
D9C18_05940	COG3866	Pectate lyase
D9C18_05950	COG0513	Belongs to the DEAD box helicase family
D9C18_05955	COG0488	(ABC) transporter
D9C18_05975	COG2814	Major facilitator Superfamily
D9C18_05980	COG0789	Transcriptional regulator
D9C18_05990	COG0488	(ABC) transporter
D9C18_05995	COG0840	transmembrane signaling receptor activity
D9C18_06000	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_06005	COG0531	amino acid
D9C18_06010	COG1011	Hydrolase
D9C18_06015	COG2223	nitrite transmembrane transporter activity
D9C18_06020	COG1442	glycosyl transferase family 8
D9C18_06025	COG1216	Glycosyl transferase, family 2
D9C18_06030	COG1442	glycosyl transferase family 8
D9C18_06035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C18_06040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9C18_06045	COG1368	sulfuric ester hydrolase activity
D9C18_06055	COG2124	cytochrome p450
D9C18_06055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C18_06065	COG3328	transposase activity
D9C18_06080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9C18_06085	COG0670	Belongs to the BI1 family
D9C18_06090	COG5583	Uncharacterized small protein (DUF2292)
D9C18_06105	COG0346	lactoylglutathione lyase activity
D9C18_06110	COG2329	Antibiotic biosynthesis monooxygenase
D9C18_06115	COG2323	membrane
D9C18_06120	COG1486	melibiose metabolic process
D9C18_06125	COG0395	ABC-type sugar transport system, permease component
D9C18_06130	COG4209	transmembrane transport
D9C18_06135	COG1653	transport
D9C18_06150	COG2755	lipolytic protein G-D-S-L family
D9C18_06155	COG3401	FG-GAP repeat protein
D9C18_06160	COG3401	FG-GAP repeat protein
D9C18_06165	COG5578	integral membrane protein
D9C18_06175	COG2755	lipolytic protein G-D-S-L family
D9C18_06180	COG2207	Transcriptional regulator
D9C18_06185	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C18_06190	COG0395	ABC-type sugar transport system, permease component
D9C18_06195	COG1175	transmembrane transport
D9C18_06200	COG1653	transport
D9C18_06210	COG2972	Histidine kinase
D9C18_06215	COG5578	integral membrane protein
D9C18_06225	COG0454	-acetyltransferase
D9C18_06230	COG3546	catalase activity
D9C18_06245	COG1309	transcriptional regulator
D9C18_06255	COG0217	transcriptional regulatory protein
D9C18_06265	COG0457	Tetratricopeptide repeat
D9C18_06275	COG5444	nuclease activity
D9C18_06310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C18_06315	COG1597	lipid kinase activity
D9C18_06320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9C18_06325	COG1309	transcriptional regulator
D9C18_06330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C18_06335	COG0154	amidase activity
D9C18_06340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C18_06345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C18_06350	COG1285	pathogenesis
D9C18_06355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C18_06365	COG4851	CamS sex pheromone cAM373 precursor
D9C18_06370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9C18_06375	COG0210	DNA helicase
D9C18_06380	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9C18_06385	COG0069	glutamate synthase activity
D9C18_06390	COG4496	protein, YerC YecD
D9C18_06395	COG1470	cell adhesion involved in biofilm formation
D9C18_06400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C18_06410	COG0531	amino acid
D9C18_06415	COG1522	sequence-specific DNA binding
D9C18_06420	COG0151	Belongs to the GarS family
D9C18_06425	COG0138	bifunctional purine biosynthesis protein purh
D9C18_06430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9C18_06435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9C18_06440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9C18_06445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C18_06450	COG0047	phosphoribosylformylglycinamidine synthase activity
D9C18_06455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C18_06460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9C18_06465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9C18_06470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9C18_06475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9C18_06485	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9C18_06495	COG3064	Membrane
D9C18_06500	COG2252	PERMEase
D9C18_06510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9C18_06510	COG0519	Catalyzes the synthesis of GMP from XMP
D9C18_06515	COG1305	Transglutaminase-like
D9C18_06520	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9C18_06525	COG0714	Associated with various cellular activities
D9C18_06530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C18_06540	COG1113	amino acid transport
D9C18_06545	COG2132	Multicopper oxidase
D9C18_06555	COG2267	carboxylic ester hydrolase activity
D9C18_06575	COG0823	Involved in the tonB-independent uptake of proteins
D9C18_06580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9C18_06585	COG1063	alcohol dehydrogenase
D9C18_06590	COG2814	Major facilitator Superfamily
D9C18_06600	COG4260	virion core protein, lumpy skin disease virus
D9C18_06605	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D9C18_06610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C18_06620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C18_06625	COG2211	Major facilitator Superfamily
D9C18_06630	COG1063	alcohol dehydrogenase
D9C18_06635	COG0457	Tetratricopeptide repeat
D9C18_06650	COG0459	protein refolding
D9C18_06655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9C18_06660	COG1266	CAAX protease self-immunity
D9C18_06675	COG0805	protein transport
D9C18_06680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C18_06685	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9C18_06690	COG0315	cyclic pyranopterin monophosphate synthase activity
D9C18_06695	COG0488	(ABC) transporter
D9C18_06705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9C18_06710	COG0456	acetyltransferase
D9C18_06715	COG1214	PFAM Peptidase M22, glycoprotease
D9C18_06720	COG0802	atpase or kinase
D9C18_06725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9C18_06770	COG4124	Belongs to the glycosyl hydrolase 26 family
D9C18_06780	COG1940	carbohydrate kinase activity
D9C18_06785	COG2188	Transcriptional regulator
D9C18_06790	COG2723	6-phospho-beta-galactosidase activity
D9C18_06805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C18_06810	COG2814	Major facilitator Superfamily
D9C18_06815	COG1388	LysM domain
D9C18_06820	COG1078	dGTPase activity
D9C18_06825	COG0454	-acetyltransferase
D9C18_06835	COG5646	InterPro IPR014922
D9C18_06840	COG1785	Belongs to the alkaline phosphatase family
D9C18_06850	COG1819	glycosyl
D9C18_06855	COG3858	chitin binding
D9C18_06855	COG1388	LysM domain
D9C18_06860	COG1802	Transcriptional regulator
D9C18_06865	COG0730	response to heat
D9C18_06870	COG2814	Major facilitator Superfamily
D9C18_06875	COG1846	Transcriptional regulator
D9C18_06880	COG0778	Nitroreductase
D9C18_06885	COG2409	Drug exporters of the RND superfamily
D9C18_06885	COG1033	growth of symbiont in host cell
D9C18_06890	COG1846	Transcriptional regulator
D9C18_06895	COG2318	DinB family
D9C18_06900	COG1113	amino acid transport
D9C18_06910	COG0456	acetyltransferase
D9C18_06920	COG1309	transcriptional regulator
D9C18_06935	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C18_06940	COG2323	membrane
D9C18_06965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_06970	COG2259	Doxx family
D9C18_06975	COG0346	lactoylglutathione lyase activity
D9C18_06980	COG0778	Nitroreductase
D9C18_06985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C18_06990	COG0789	Transcriptional regulator
D9C18_06990	COG4978	Transcriptional regulator
D9C18_06995	COG1811	Na channel or pump
D9C18_07000	COG0596	Alpha beta hydrolase
D9C18_07005	COG2409	Drug exporters of the RND superfamily
D9C18_07010	COG2197	response regulator
D9C18_07015	COG4585	Histidine kinase
D9C18_07030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C18_07035	COG0640	Transcriptional regulator
D9C18_07040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C18_07045	COG0076	glutamate decarboxylase activity
D9C18_07050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C18_07055	COG0697	spore germination
D9C18_07060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_07070	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C18_07075	COG0640	Transcriptional regulator
D9C18_07080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C18_07090	COG3545	Serine hydrolase
D9C18_07095	COG2030	dehydratase
D9C18_07100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C18_07105	COG0697	spore germination
D9C18_07110	COG1309	transcriptional regulator
D9C18_07115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_07130	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D9C18_07145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C18_07150	COG3708	Transcriptional regulator
D9C18_07150	COG2207	Transcriptional regulator
D9C18_07160	COG1917	Cupin 2, conserved barrel domain protein
D9C18_07160	COG2207	Transcriptional regulator
D9C18_07165	COG0697	spore germination
D9C18_07175	COG1329	Transcriptional regulator
D9C18_07180	COG1278	Cold shock
D9C18_07185	COG0693	protein deglycase activity
D9C18_07210	COG1476	TRANSCRIPTIONal
D9C18_07220	COG5444	nuclease activity
D9C18_07230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_07235	COG0583	DNA-binding transcription factor activity
D9C18_07270	COG0457	Tetratricopeptide repeat
D9C18_07285	COG0741	lytic transglycosylase activity
D9C18_07285	COG0791	NLP P60 protein
D9C18_07295	COG5644	endopeptidase inhibitor activity
D9C18_07305	COG0433	COG0433 Predicted ATPase
D9C18_07345	COG2946	Replication initiation factor
D9C18_07350	COG1674	ftsk spoiiie
D9C18_07380	COG1396	sequence-specific DNA binding
D9C18_07385	COG2856	Zn peptidase
D9C18_07390	COG0582	viral genome integration into host DNA
D9C18_07430	COG3091	SprT-like family
D9C18_07440	COG2183	response to ionizing radiation
D9C18_07445	COG1846	Transcriptional regulator
D9C18_07450	COG1673	EVE domain
D9C18_07465	COG2208	phosphoserine phosphatase activity
D9C18_07470	COG1191	sigma factor activity
D9C18_07475	COG2172	sigma factor antagonist activity
D9C18_07480	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_07485	COG2208	phosphoserine phosphatase activity
D9C18_07490	COG2172	sigma factor antagonist activity
D9C18_07495	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_07500	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_07505	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9C18_07510	COG0864	Transcriptional regulator
D9C18_07515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C18_07520	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9C18_07525	COG0736	holo-[acyl-carrier-protein] synthase activity
D9C18_07530	COG0705	Rhomboid family
D9C18_07535	COG3428	Bacterial PH domain
D9C18_07540	COG3402	PFAM membrane-flanked domain
D9C18_07545	COG0513	Belongs to the DEAD box helicase family
D9C18_07555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9C18_07560	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9C18_07565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_07570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C18_07585	COG1960	acyl-CoA dehydrogenase activity
D9C18_07595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C18_07600	COG1131	(ABC) transporter
D9C18_07605	COG0628	permease
D9C18_07610	COG1301	dicarboxylic acid transport
D9C18_07615	COG4565	transcriptional regulatory protein
D9C18_07620	COG3290	protein histidine kinase activity
D9C18_07625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9C18_07630	COG3546	catalase activity
D9C18_07635	COG2329	Antibiotic biosynthesis monooxygenase
D9C18_07640	COG0662	Cupin 2, conserved barrel domain protein
D9C18_07645	COG3729	General stress protein
D9C18_07650	COG2217	Heavy metal translocating P-type atpase
D9C18_07655	COG4876	unkown
D9C18_07660	COG2261	transglycosylase associated protein
D9C18_07665	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C18_07695	COG0028	Belongs to the TPP enzyme family
D9C18_07700	COG0494	nUDIX hydrolase
D9C18_07705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C18_07705	COG0551	DNA topoisomerase type I activity
D9C18_07710	COG1522	sequence-specific DNA binding
D9C18_07715	COG2814	Major facilitator Superfamily
D9C18_07725	COG3871	stress protein (general stress protein 26)
D9C18_07730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_07735	COG1917	Cupin 2, conserved barrel domain protein
D9C18_07740	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_07745	COG2226	methyltransferase
D9C18_07750	COG0318	PFAM AMP-dependent synthetase and ligase
D9C18_07755	COG3711	transcriptional antiterminator
D9C18_07760	COG4989	oxidoreductase activity
D9C18_07765	COG0768	penicillin binding
D9C18_07770	COG2329	Antibiotic biosynthesis monooxygenase
D9C18_07780	COG2755	lipolytic protein G-D-S-L family
D9C18_07785	COG1414	Transcriptional regulator
D9C18_07790	COG1984	allophanate hydrolase subunit 2
D9C18_07795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9C18_07800	COG4336	lyase activity
D9C18_07805	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C18_07810	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9C18_07815	COG0561	phosphatase activity
D9C18_07825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C18_07835	COG0681	Belongs to the peptidase S26 family
D9C18_07840	COG0473	3-isopropylmalate dehydrogenase activity
D9C18_07845	COG0246	Mannitol dehydrogenase
D9C18_07850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_07855	COG2213	PTS system mannitol-specific
D9C18_07865	COG1349	DNA-binding transcription factor activity
D9C18_07870	COG2372	response to copper ion
D9C18_07870	COG1276	copper resistance
D9C18_07875	COG4549	nuclear export factor GLE1
D9C18_07880	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_07885	COG4975	Glucose uptake
D9C18_07890	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_07895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9C18_07900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C18_07905	COG0640	Transcriptional regulator
D9C18_07910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C18_07915	COG0778	Nitroreductase
D9C18_07920	COG1309	transcriptional regulator
D9C18_07925	COG2814	Major facilitator Superfamily
D9C18_07935	COG4607	ABC-type enterochelin transport system periplasmic component
D9C18_07940	COG4604	ABC transporter, ATP-binding protein
D9C18_07945	COG4605	iron ion homeostasis
D9C18_07950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_07955	COG0527	aspartate kinase activity
D9C18_07975	COG0457	Tetratricopeptide repeat
D9C18_07980	COG5002	protein histidine kinase activity
D9C18_07980	COG3850	Histidine kinase
D9C18_07985	COG0745	RESPONSE REGULATOR receiver
D9C18_07990	COG0577	efflux transmembrane transporter activity
D9C18_07995	COG1136	(ABC) transporter
D9C18_08000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C18_08010	COG0697	spore germination
D9C18_08020	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C18_08025	COG3104	oligopeptide transport
D9C18_08030	COG0596	Alpha beta hydrolase
D9C18_08045	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9C18_08050	COG0163	prenyltransferase activity
D9C18_08055	COG0583	DNA-binding transcription factor activity
D9C18_08060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C18_08065	COG0765	amino acid transport
D9C18_08070	COG1126	abc transporter atp-binding protein
D9C18_08075	COG2364	Membrane
D9C18_08085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C18_08090	COG0697	spore germination
D9C18_08100	COG2814	Major facilitator Superfamily
D9C18_08105	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9C18_08110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C18_08115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C18_08120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C18_08125	COG1733	regulation of RNA biosynthetic process
D9C18_08130	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9C18_08135	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9C18_08145	COG3209	COG3209 Rhs family protein
D9C18_08155	COG2723	6-phospho-beta-galactosidase activity
D9C18_08170	COG1846	Transcriptional regulator
D9C18_08180	COG1714	RDD family
D9C18_08190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C18_08195	COG0765	amino acid transport
D9C18_08210	COG1376	ErfK ybiS ycfS ynhG family protein
D9C18_08220	COG2223	nitrite transmembrane transporter activity
D9C18_08225	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C18_08230	COG0243	molybdopterin cofactor binding
D9C18_08235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C18_08240	COG2146	nitrite reductase [NAD(P)H] activity
D9C18_08245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C18_08245	COG1587	Uroporphyrinogen-III synthase
D9C18_08250	COG0492	ferredoxin-NADP+ reductase activity
D9C18_08255	COG2267	carboxylic ester hydrolase activity
D9C18_08260	COG0701	Predicted permease
D9C18_08265	COG3689	TIGRFAM TIGR03943 family protein
D9C18_08270	COG2508	Transcriptional regulator
D9C18_08275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C18_08280	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_08285	COG0506	proline dehydrogenase activity
D9C18_08290	COG3541	Predicted nucleotidyltransferase
D9C18_08295	COG3458	cephalosporin-C deacetylase activity
D9C18_08300	COG0583	DNA-binding transcription factor activity
D9C18_08305	COG2226	methyltransferase
D9C18_08315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9C18_08325	COG1660	Displays ATPase and GTPase activities
D9C18_08330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9C18_08345	COG3403	YqcI/YcgG family
D9C18_08360	COG0039	L-malate dehydrogenase activity
D9C18_08375	COG1288	antiporter activity
D9C18_08380	COG1473	amidohydrolase
D9C18_08385	COG2113	Glycine betaine
D9C18_08390	COG4176	ABC-type proline glycine betaine transport system permease component
D9C18_08395	COG4175	Glycine betaine
D9C18_08395	COG0517	IMP dehydrogenase activity
D9C18_08400	COG0640	Transcriptional regulator
D9C18_08405	COG2814	Major facilitator Superfamily
D9C18_08410	COG0477	Major facilitator Superfamily
D9C18_08420	COG3853	Toxic anion resistance protein (TelA)
D9C18_08430	COG0861	Integral membrane protein TerC family
D9C18_08435	COG2310	stress, protein
D9C18_08440	COG2310	stress, protein
D9C18_08445	COG2310	stress, protein
D9C18_08455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C18_08460	COG1121	(ABC) transporter
D9C18_08465	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C18_08470	COG0366	Alpha amylase catalytic
D9C18_08475	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_08485	COG1876	peptidase activity
D9C18_08490	COG1595	DNA-templated transcription, initiation
D9C18_08495	COG1595	DNA-templated transcription, initiation
D9C18_08510	COG0667	Aldo Keto reductase
D9C18_08515	COG1668	transmembrane transport
D9C18_08525	COG3279	Response regulator of the LytR AlgR family
D9C18_08535	COG3012	SEC-C Motif Domain Protein
D9C18_08535	COG1405	negative regulation of cell septum assembly
D9C18_08540	COG1714	RDD family
D9C18_08545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C18_08550	COG0252	asparaginase activity
D9C18_08555	COG1309	transcriptional regulator
D9C18_08560	COG0477	Major facilitator Superfamily
D9C18_08565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C18_08570	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D9C18_08575	COG0805	protein transport
D9C18_08580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C18_08585	COG3540	Alkaline phosphatase
D9C18_08595	COG2304	oxidoreductase activity
D9C18_08600	COG3773	Cell wall hydrolase
D9C18_08620	COG1131	(ABC) transporter
D9C18_08625	COG2205	protein histidine kinase activity
D9C18_08630	COG0745	RESPONSE REGULATOR receiver
D9C18_08635	COG0697	spore germination
D9C18_08645	COG3173	Aminoglycoside phosphotransferase
D9C18_08650	COG2721	sulfolactate sulfo-lyase activity
D9C18_08655	COG2186	Transcriptional regulator
D9C18_08660	COG4948	Mandelate Racemase Muconate Lactonizing
D9C18_08665	COG2271	Major facilitator Superfamily
D9C18_08670	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_08675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C18_08685	COG0784	Response regulator, receiver
D9C18_08690	COG4191	Histidine kinase
D9C18_08695	COG2066	Belongs to the glutaminase family
D9C18_08710	COG2040	homocysteine
D9C18_08715	COG0833	amino acid
D9C18_08720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C18_08735	COG0363	glucosamine-6-phosphate deaminase activity
D9C18_08740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_08740	COG2190	(PTS) system
D9C18_08740	COG1263	PTS System
D9C18_08745	COG1301	dicarboxylic acid transport
D9C18_08755	COG2207	Transcriptional regulator
D9C18_08760	COG2312	Erythromycin esterase
D9C18_08770	COG0688	phosphatidylethanolamine metabolic process
D9C18_08775	COG0586	Pfam SNARE associated Golgi protein
D9C18_08780	COG1183	phosphatidylcholine synthase activity
D9C18_08785	COG0596	Alpha beta hydrolase
D9C18_08795	COG3591	Belongs to the peptidase S1B family
D9C18_08800	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9C18_08825	COG2207	Transcriptional regulator
D9C18_08825	COG1917	Cupin 2, conserved barrel domain protein
D9C18_08830	COG0697	spore germination
D9C18_08835	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_08855	COG0456	acetyltransferase
D9C18_08855	COG1846	Transcriptional regulator
D9C18_08870	COG2271	Major facilitator Superfamily
D9C18_08875	COG0584	glycerophosphoryl diester phosphodiesterase
D9C18_08880	COG0531	amino acid
D9C18_08890	COG2124	cytochrome p450
D9C18_08895	COG2602	Beta-lactamase
D9C18_08910	COG1113	amino acid transport
D9C18_08925	COG0515	serine threonine protein kinase
D9C18_08935	COG0642	Histidine kinase
D9C18_08945	COG5609	conserved protein (DUF2294)
D9C18_08955	COG0288	reversible hydration of carbon dioxide
D9C18_08960	COG3002	Belongs to the UPF0753 family
D9C18_08965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C18_08970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C18_08975	COG2169	Transcriptional regulator
D9C18_08990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9C18_09000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C18_09005	COG4856	YbbR-like protein
D9C18_09010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C18_09015	COG5662	AntiSigma factor
D9C18_09020	COG1595	DNA-templated transcription, initiation
D9C18_09050	COG1683	Conserved Protein
D9C18_09055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_09060	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9C18_09065	COG1737	Transcriptional regulator
D9C18_09070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_09070	COG1263	PTS System
D9C18_09075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C18_09080	COG1472	Belongs to the glycosyl hydrolase 3 family
D9C18_09085	COG3876	Protein conserved in bacteria
D9C18_09090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C18_09090	COG2207	Transcriptional regulator
D9C18_09095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C18_09100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_09105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_09110	COG2819	hydrolase of the alpha beta superfamily
D9C18_09115	COG0385	Bile acid
D9C18_09120	COG0659	secondary active sulfate transmembrane transporter activity
D9C18_09205	COG0726	polysaccharide deacetylase
D9C18_09210	COG2194	sulfuric ester hydrolase activity
D9C18_09220	COG0489	protein tyrosine kinase activity
D9C18_09225	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C18_09235	COG2226	methyltransferase
D9C18_09245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9C18_09250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9C18_09255	COG0101	tRNA pseudouridine synthase activity
D9C18_09260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C18_09265	COG1122	ATPase activity
D9C18_09270	COG1122	ATPase activity
D9C18_09275	COG0203	ribosomal protein L17
D9C18_09280	COG0202	RNA polymerase activity
D9C18_09285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9C18_09290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9C18_09295	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9C18_09300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9C18_09305	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9C18_09310	COG0024	Methionine aminopeptidase
D9C18_09315	COG0563	adenylate kinase activity
D9C18_09320	COG0201	protein transport
D9C18_09325	COG0200	Binds to the 23S rRNA
D9C18_09330	COG1841	ribosomal large subunit assembly
D9C18_09335	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9C18_09340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9C18_09345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9C18_09350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9C18_09360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9C18_09370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9C18_09375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9C18_09380	COG0255	Belongs to the universal ribosomal protein uL29 family
D9C18_09385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9C18_09390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9C18_09395	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9C18_09400	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9C18_09405	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9C18_09410	COG0089	rRNA binding
D9C18_09415	COG0088	Forms part of the polypeptide exit tunnel
D9C18_09420	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9C18_09425	COG0051	transcription antitermination factor activity, RNA binding
D9C18_09430	COG0596	Alpha beta hydrolase
D9C18_09435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9C18_09440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9C18_09445	COG0049	tRNA binding
D9C18_09450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9C18_09455	COG1358	cellular component organization or biogenesis
D9C18_09460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9C18_09465	COG0085	RNA polymerase activity
D9C18_09470	COG2813	Specifically methylates the guanine in position
D9C18_09475	COG0222	ribosome binding
D9C18_09480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9C18_09485	COG0081	regulation of translation
D9C18_09490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9C18_09495	COG0250	Participates in transcription elongation, termination and antitermination
D9C18_09500	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C18_09505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C18_09510	COG1595	DNA-templated transcription, initiation
D9C18_09515	COG3688	RNA-binding protein containing a PIN domain
D9C18_09520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C18_09525	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9C18_09530	COG0215	cysteine-tRNA ligase activity
D9C18_09535	COG1045	serine acetyltransferase
D9C18_09545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9C18_09550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9C18_09555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9C18_09560	COG4956	integral membrane protein (PIN domain superfamily)
D9C18_09565	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9C18_09570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9C18_09575	COG0542	response to heat
D9C18_09580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9C18_09585	COG3880	PFAM UvrB UvrC protein
D9C18_09590	COG4463	regulation of RNA biosynthetic process
D9C18_09670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9C18_09675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C18_09680	COG1396	sequence-specific DNA binding
D9C18_09685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9C18_09690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9C18_09695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9C18_09700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C18_09705	COG0512	Glutamine amidotransferase of anthranilate synthase
D9C18_09710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C18_09715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C18_09720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C18_09725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9C18_09730	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9C18_09735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C18_09745	COG0037	tRNA processing
D9C18_09755	COG2304	oxidoreductase activity
D9C18_09760	COG2208	phosphoserine phosphatase activity
D9C18_09775	COG1098	S1 RNA binding domain
D9C18_09780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9C18_09795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9C18_09800	COG3956	TIGRFAM MazG family protein
D9C18_09805	COG2244	polysaccharide biosynthetic process
D9C18_09810	COG2002	toxin-antitoxin pair type II binding
D9C18_09815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9C18_09825	COG0193	aminoacyl-tRNA hydrolase activity
D9C18_09830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9C18_09835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9C18_09840	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9C18_09845	COG2088	sporulation resulting in formation of a cellular spore
D9C18_09850	COG0251	oxidation-reduction process
D9C18_09855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C18_09860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9C18_09870	COG4466	Protein conserved in bacteria
D9C18_09880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9C18_09885	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C18_09890	COG3583	domain protein
D9C18_09890	COG3584	3D domain protein
D9C18_09895	COG0084	hydrolase, TatD family'
D9C18_09900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C18_09900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C18_09905	COG2002	toxin-antitoxin pair type II binding
D9C18_09910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9C18_09915	COG2827	Endonuclease containing a URI domain
D9C18_09920	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9C18_09925	COG4467	Involved in initiation control of chromosome replication
D9C18_09930	COG1774	PSP1 C-terminal conserved region
D9C18_09935	COG0470	DNA polymerase III
D9C18_09940	COG1728	Protein conserved in bacteria
D9C18_09945	COG3870	Protein conserved in bacteria
D9C18_09950	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C18_09955	COG1982	Orn Lys Arg decarboxylase major
D9C18_09960	COG3853	Toxic anion resistance protein (TelA)
D9C18_09965	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9C18_10010	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9C18_10015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9C18_10020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9C18_10030	COG0590	tRNA wobble adenosine to inosine editing
D9C18_10035	COG1335	isochorismatase
D9C18_10040	COG3858	chitin binding
D9C18_10040	COG1388	LysM domain
D9C18_10045	COG1428	Deoxynucleoside kinase
D9C18_10050	COG1428	Deoxynucleoside kinase
D9C18_10060	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9C18_10065	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9C18_10070	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9C18_10075	COG1686	Belongs to the peptidase S11 family
D9C18_10080	COG0517	IMP dehydrogenase activity
D9C18_10080	COG0516	GMP reductase activity
D9C18_10115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C18_10120	COG0187	DNA topoisomerase II activity
D9C18_10130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9C18_10135	COG2501	S4 domain
D9C18_10140	COG0592	DNA-directed DNA polymerase activity
D9C18_10145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9C18_10150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D9C18_10155	COG0594	ribonuclease P activity
D9C18_10160	COG0706	membrane insertase activity
D9C18_10165	COG1847	R3H domain protein
D9C18_10170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9C18_10175	COG0445	tRNA wobble uridine modification
D9C18_10180	COG0357	Ribosomal RNA small subunit methyltransferase G
D9C18_10185	COG1475	DNA binding
D9C18_10195	COG1192	Involved in chromosome partitioning
D9C18_10200	COG1475	DNA binding
D9C18_10210	COG3949	Membrane
D9C18_10215	COG4481	Protein conserved in bacteria
D9C18_10220	COG0243	molybdopterin cofactor binding
D9C18_10225	COG0012	GTP binding
D9C18_10230	COG0360	Binds together with S18 to 16S ribosomal RNA
D9C18_10235	COG0629	single-stranded DNA binding
D9C18_10240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9C18_10245	COG0708	Exodeoxyribonuclease III
D9C18_10260	COG0542	response to heat
D9C18_10265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C18_10270	COG0346	lactoylglutathione lyase activity
D9C18_10275	COG0477	Major facilitator Superfamily
D9C18_10275	COG2814	Major facilitator Superfamily
D9C18_10280	COG1266	CAAX protease self-immunity
D9C18_10285	COG1331	Highly conserved protein containing a thioredoxin domain
D9C18_10290	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D9C18_10295	COG1331	Highly conserved protein containing a thioredoxin domain
D9C18_10300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C18_10305	COG2315	Protein conserved in bacteria
D9C18_10310	COG0456	acetyltransferase
D9C18_10315	COG2364	Membrane
D9C18_10320	COG2153	protein acetylation
D9C18_10325	COG1846	Transcriptional regulator
D9C18_10340	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C18_10345	COG4319	ketosteroid isomerase
D9C18_10355	COG4978	Transcriptional regulator
D9C18_10355	COG0789	Transcriptional regulator
D9C18_10360	COG2271	Major facilitator Superfamily
D9C18_10375	COG1227	inorganic diphosphatase activity
D9C18_10380	COG1733	regulation of RNA biosynthetic process
D9C18_10400	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9C18_10405	COG0359	binds to the 23S rRNA
D9C18_10410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C18_10415	COG2807	transmembrane transport
D9C18_10420	COG3093	addiction module antidote protein HigA
D9C18_10435	COG0305	Participates in initiation and elongation during chromosome replication
D9C18_10440	COG0346	lactoylglutathione lyase activity
D9C18_10470	COG0745	RESPONSE REGULATOR receiver
D9C18_10475	COG5002	protein histidine kinase activity
D9C18_10480	COG4863	YycH protein
D9C18_10485	COG4853	Protein conserved in bacteria
D9C18_10490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9C18_10495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C18_10510	COG3829	transcription factor binding
D9C18_10515	COG0640	Transcriptional regulator
D9C18_10520	COG5658	integral membrane protein
D9C18_10540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C18_10545	COG0833	amino acid
D9C18_10550	COG0010	Belongs to the arginase family
D9C18_10560	COG0457	Tetratricopeptide repeat
D9C18_10565	COG0456	acetyltransferase
D9C18_10570	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D9C18_10590	COG1063	alcohol dehydrogenase
D9C18_10605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9C18_10660	COG2963	transposase activity
D9C18_10690	COG0210	DNA helicase
D9C18_10725	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C18_10740	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D9C18_10745	COG1131	(ABC) transporter
D9C18_10755	COG2188	Transcriptional regulator
D9C18_10770	COG2723	6-phospho-beta-galactosidase activity
D9C18_10775	COG3634	alkyl hydroperoxide reductase activity
D9C18_10780	COG0450	alkyl hydroperoxide reductase
D9C18_10785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C18_10790	COG2610	gluconate transmembrane transporter activity
D9C18_10795	COG1070	Carbohydrate kinase
D9C18_10800	COG1802	Transcriptional regulator
D9C18_10805	COG1929	Belongs to the glycerate kinase type-1 family
D9C18_10810	COG5039	Polysaccharide pyruvyl transferase
D9C18_10815	COG1346	cytolysis
D9C18_10820	COG1380	Effector of murein hydrolase LrgA
D9C18_10825	COG1846	Transcriptional regulator
D9C18_10830	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_10835	COG1309	transcriptional regulator
D9C18_10840	COG1917	Cupin 2, conserved barrel domain protein
D9C18_10905	COG0326	Molecular chaperone. Has ATPase activity
D9C18_10935	COG0667	Aldo Keto reductase
D9C18_10940	COG1349	DNA-binding transcription factor activity
D9C18_10960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C18_10965	COG3962	Belongs to the TPP enzyme family
D9C18_10970	COG1082	Xylose isomerase domain protein TIM barrel
D9C18_10975	COG2814	Major facilitator Superfamily
D9C18_10980	COG0673	inositol 2-dehydrogenase activity
D9C18_10985	COG1082	Xylose isomerase domain protein TIM barrel
D9C18_10990	COG1082	Xylose isomerase domain protein TIM barrel
D9C18_10995	COG0191	fructose-bisphosphate aldolase activity
D9C18_11000	COG0745	RESPONSE REGULATOR receiver
D9C18_11005	COG2205	protein histidine kinase activity
D9C18_11020	COG5294	Protein conserved in bacteria
D9C18_11025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C18_11055	COG0561	phosphatase activity
D9C18_11060	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9C18_11075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C18_11080	COG0765	amino acid transport
D9C18_11085	COG1126	abc transporter atp-binding protein
D9C18_11095	COG2079	MmgE PrpD family protein
D9C18_11100	COG3192	ethanolamine utilization protein
D9C18_11110	COG2390	Transcriptional regulator
D9C18_11115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9C18_11120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C18_11125	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9C18_11140	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C18_11145	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
D9C18_11150	COG0494	nUDIX hydrolase
D9C18_11170	COG5444	nuclease activity
D9C18_11190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_11190	COG2190	(PTS) system
D9C18_11190	COG1263	PTS System
D9C18_11200	COG0589	response to stress
D9C18_11215	COG0697	spore germination
D9C18_11335	COG2755	lipolytic protein G-D-S-L family
D9C18_11335	COG3401	FG-GAP repeat protein
D9C18_11340	COG0513	Belongs to the DEAD box helicase family
D9C18_11345	COG2270	Major facilitator Superfamily
D9C18_11360	COG3711	transcriptional antiterminator
D9C18_11365	COG2273	Hydrolase Family 16
D9C18_11370	COG2851	Citrate transporter
D9C18_11375	COG0753	catalase activity
D9C18_11375	COG0693	protein deglycase activity
D9C18_11390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C18_11395	COG0500	methyltransferase
D9C18_11400	COG2610	gluconate transmembrane transporter activity
D9C18_11405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C18_11410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C18_11415	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_11420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C18_11425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C18_11430	COG4894	glucomannan catabolic process
D9C18_11440	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C18_11445	COG2197	response regulator
D9C18_11450	COG4585	Histidine kinase
D9C18_11460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9C18_11470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C18_11475	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_11480	COG2508	Transcriptional regulator
D9C18_11485	COG3842	ATPase activity
D9C18_11490	COG0726	polysaccharide deacetylase
D9C18_11500	COG0501	Belongs to the peptidase M48B family
D9C18_11505	COG3493	citrate carrier protein
D9C18_11510	COG1271	oxidase subunit
D9C18_11515	COG1294	oxidase, subunit
D9C18_11520	COG4988	ABC transporter
D9C18_11525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9C18_11530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9C18_11535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C18_11540	COG1595	DNA-templated transcription, initiation
D9C18_11560	COG1131	(ABC) transporter
D9C18_11565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C18_11570	COG2814	Major facilitator Superfamily
D9C18_11575	COG0753	catalase activity
D9C18_11580	COG2094	Belongs to the DNA glycosylase MPG family
D9C18_11590	COG3711	transcriptional antiterminator
D9C18_11590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_11595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C18_11600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C18_11605	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C18_11615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C18_11625	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9C18_11630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C18_11635	COG1696	Membrane protein involved in D-alanine export
D9C18_11640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C18_11660	COG1575	Belongs to the MenA family. Type 1 subfamily
D9C18_11670	COG2357	RelA SpoT domain protein
D9C18_11675	COG2234	aminopeptidase activity
D9C18_11680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C18_11685	COG1846	Transcriptional regulator
D9C18_11690	COG5522	Integral membrane protein (intg_mem_TP0381)
D9C18_11695	COG1442	glycosyl transferase family 8
D9C18_11700	COG3711	transcriptional antiterminator
D9C18_11705	COG1263	PTS System
D9C18_11705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_11715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C18_11725	COG0346	lactoylglutathione lyase activity
D9C18_11730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9C18_11735	COG4895	conserved protein (DUF2196)
D9C18_11740	COG2814	Major facilitator Superfamily
D9C18_11745	COG1346	cytolysis
D9C18_11750	COG1380	Effector of murein hydrolase LrgA
D9C18_11755	COG0583	DNA-binding transcription factor activity
D9C18_11760	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9C18_11765	COG0352	thiamine-phosphate diphosphorylase activity
D9C18_11770	COG0672	)-iron permease
D9C18_11775	COG2822	iron ion transport
D9C18_11780	COG2837	iron assimilation
D9C18_11785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9C18_11790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C18_11795	COG3162	membrane
D9C18_11805	COG1309	transcriptional regulator
D9C18_11810	COG2246	polysaccharide biosynthetic process
D9C18_11815	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9C18_11820	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9C18_11825	COG2261	transglycosylase associated protein
D9C18_11830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C18_11835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C18_11840	COG1845	cytochrome c oxidase, subunit III
D9C18_11845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C18_11860	COG0772	Belongs to the SEDS family
D9C18_11865	COG0778	Nitroreductase
D9C18_11870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C18_11875	COG1404	Belongs to the peptidase S8 family
D9C18_11890	COG2116	formate transmembrane transporter activity
D9C18_11895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_11895	COG1263	PTS System
D9C18_11900	COG1621	beta-fructofuranosidase activity
D9C18_11910	COG0351	phosphomethylpyrimidine kinase
D9C18_11915	COG1216	Glycosyl transferase, family 2
D9C18_11920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9C18_11925	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_11935	COG2233	PERMEase
D9C18_11940	COG2363	Small membrane protein
D9C18_11955	COG0463	Glycosyl transferase, family 2
D9C18_11960	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C18_11965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C18_11970	COG0456	acetyltransferase
D9C18_11975	COG2089	acid synthase
D9C18_11980	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D9C18_11985	COG3980	spore coat polysaccharide biosynthesis protein
D9C18_11990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9C18_11995	COG1088	dTDP-glucose 4,6-dehydratase activity
D9C18_12000	COG1091	dTDP-4-dehydrorhamnose reductase activity
D9C18_12005	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D9C18_12015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C18_12020	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_12025	COG4187	Peptidase family M20/M25/M40
D9C18_12030	COG0833	amino acid
D9C18_12035	COG2814	Major facilitator Superfamily
D9C18_12040	COG0077	Prephenate dehydratase
D9C18_12045	COG1917	Cupin 2, conserved barrel domain protein
D9C18_12050	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_12055	COG0151	Belongs to the GarS family
D9C18_12060	COG2814	Major facilitator Superfamily
D9C18_12065	COG0436	Aminotransferase
D9C18_12070	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_12080	COG0280	phosphate acetyltransferase
D9C18_12085	COG0583	DNA-binding transcription factor activity
D9C18_12090	COG0095	Lipoate-protein ligase
D9C18_12095	COG0697	spore germination
D9C18_12105	COG4844	belongs to the
D9C18_12110	COG1078	dGTPase activity
D9C18_12115	COG3465	dGTPase activity
D9C18_12120	COG1959	2 iron, 2 sulfur cluster binding
D9C18_12125	COG0477	Major facilitator Superfamily
D9C18_12135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C18_12140	COG1846	Transcriptional regulator
D9C18_12145	COG1942	4-Oxalocrotonate Tautomerase
D9C18_12150	COG1994	Peptidase M50
D9C18_12165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C18_12170	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9C18_12175	COG0010	Belongs to the arginase family
D9C18_12180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C18_12190	COG0457	Tetratricopeptide repeat
D9C18_12200	COG3391	amine dehydrogenase activity
D9C18_12205	COG3391	amine dehydrogenase activity
D9C18_12215	COG0612	Peptidase, M16
D9C18_12220	COG0612	Peptidase, M16
D9C18_12225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C18_12230	COG1131	(ABC) transporter
D9C18_12240	COG0535	radical SAM domain protein
D9C18_12255	COG4506	Protein conserved in bacteria
D9C18_12260	COG0018	arginyl-trna synthetase
D9C18_12265	COG2223	nitrite transmembrane transporter activity
D9C18_12270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C18_12280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9C18_12285	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D9C18_12290	COG1140	nitrate reductase beta subunit
D9C18_12295	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D9C18_12300	COG2181	nitrate reductase activity
D9C18_12310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C18_12320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C18_12330	COG4294	response to UV
D9C18_12335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C18_12340	COG0247	lactate metabolic process
D9C18_12340	COG2181	nitrate reductase activity
D9C18_12345	COG1960	acyl-CoA dehydrogenase activity
D9C18_12350	COG3343	RNA polymerase activity
D9C18_12355	COG0504	CTP synthase activity
D9C18_12360	COG4821	SIS domain
D9C18_12365	COG2204	response regulator
D9C18_12370	COG0191	fructose-bisphosphate aldolase activity
D9C18_12375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9C18_12380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C18_12385	COG1494	fructose-1,6-bisphosphatase
D9C18_12395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9C18_12400	COG0254	rRNA binding
D9C18_12405	COG1435	thymidine kinase activity
D9C18_12410	COG0281	malic enzyme
D9C18_12415	COG0679	Auxin Efflux Carrier
D9C18_12420	COG0789	Transcriptional regulator
D9C18_12425	COG0346	lactoylglutathione lyase activity
D9C18_12430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9C18_12435	COG2890	protein-(glutamine-N5) methyltransferase activity
D9C18_12455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9C18_12460	COG0009	L-threonylcarbamoyladenylate synthase
D9C18_12465	COG1971	Probably functions as a manganese efflux pump
D9C18_12470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C18_12475	COG0698	ribose 5-phosphate isomerase
D9C18_12480	COG4475	Protein of unknown function (DUF436)
D9C18_12485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9C18_12490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9C18_12500	COG0356	it plays a direct role in the translocation of protons across the membrane
D9C18_12505	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C18_12510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9C18_12515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C18_12520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9C18_12525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9C18_12530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9C18_12535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9C18_12545	COG4836	Membrane
D9C18_12555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C18_12560	COG2385	sporulation resulting in formation of a cellular spore
D9C18_12565	COG2304	oxidoreductase activity
D9C18_12575	COG2304	oxidoreductase activity
D9C18_12585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9C18_12590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9C18_12600	COG0457	Tetratricopeptide repeat
D9C18_12605	COG1994	Peptidase M50
D9C18_12610	COG3237	CsbD-like
D9C18_12625	COG0831	urea catabolic process
D9C18_12630	COG0832	Belongs to the urease beta subunit family
D9C18_12635	COG0804	urea catabolic process
D9C18_12640	COG1959	2 iron, 2 sulfur cluster binding
D9C18_12645	COG2910	NAD(P)H-binding
D9C18_12655	COG0789	Transcriptional regulator
D9C18_12660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C18_12670	COG2089	acid synthase
D9C18_12680	COG1247	-acetyltransferase
D9C18_12685	COG0739	heme binding
D9C18_12695	COG0671	phosphoesterase, PA-phosphatase related
D9C18_12700	COG0347	Belongs to the P(II) protein family
D9C18_12705	COG0004	ammonium transporteR
D9C18_12715	COG1335	isochorismatase
D9C18_12720	COG0477	Major facilitator Superfamily
D9C18_12725	COG1953	Uracil, thiamine, allantoin
D9C18_12730	COG3420	alginic acid biosynthetic process
D9C18_12735	COG2814	Major facilitator Superfamily
D9C18_12740	COG1846	Transcriptional regulator
D9C18_12750	COG1609	Transcriptional regulator
D9C18_12755	COG1077	Cell shape determining protein MreB Mrl
D9C18_12760	COG4786	Flagellar basal body rod
D9C18_12765	COG4786	Flagellar basal body rod
D9C18_12770	COG0457	Tetratricopeptide repeat
D9C18_12775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C18_12780	COG1970	mechanosensitive ion channel activity
D9C18_12785	COG2972	Histidine kinase
D9C18_12785	COG0745	RESPONSE REGULATOR receiver
D9C18_12795	COG3764	Sortase (surface protein transpeptidase)
D9C18_12810	COG0629	single-stranded DNA binding
D9C18_12815	COG1349	DNA-binding transcription factor activity
D9C18_12820	COG0561	phosphatase activity
D9C18_12830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C18_12835	COG4715	Zinc finger, swim domain protein
D9C18_12845	COG3944	biosynthesis protein
D9C18_12850	COG0489	protein tyrosine kinase activity
D9C18_12855	COG4464	protein tyrosine phosphatase activity
D9C18_12860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C18_12885	COG5444	nuclease activity
D9C18_12915	COG0583	DNA-binding transcription factor activity
D9C18_12920	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C18_12930	COG2059	Chromate
D9C18_12935	COG2059	Chromate
D9C18_12940	COG1522	sequence-specific DNA binding
D9C18_12945	COG0405	Gamma-glutamyltransferase
D9C18_12955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C18_12965	COG5337	Spore coat protein CotH
D9C18_12980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9C18_12985	COG0583	DNA-binding transcription factor activity
D9C18_12990	COG0028	Belongs to the TPP enzyme family
D9C18_12995	COG3527	Alpha-acetolactate decarboxylase
D9C18_13000	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C18_13010	COG3103	Sh3 type 3 domain protein
D9C18_13015	COG1879	ABC-type sugar transport system periplasmic component
D9C18_13020	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9C18_13025	COG1129	ABC transporter
D9C18_13030	COG1869	D-ribose catabolic process
D9C18_13035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C18_13040	COG1609	Transcriptional regulator
D9C18_13050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C18_13060	COG2843	Capsule synthesis protein
D9C18_13070	COG0791	NLP P60 protein
D9C18_13075	COG0561	phosphatase activity
D9C18_13080	COG1316	TRANSCRIPTIONal
D9C18_13095	COG0814	amino acid
D9C18_13100	COG0697	spore germination
D9C18_13105	COG1482	cell wall glycoprotein biosynthetic process
D9C18_13110	COG4193	domain, Protein
D9C18_13115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C18_13120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D9C18_13125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9C18_13130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C18_13135	COG0463	Glycosyl transferase, family 2
D9C18_13135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C18_13150	COG1682	transport, permease protein
D9C18_13155	COG1134	teichoic acid transport
D9C18_13165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C18_13170	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9C18_13200	COG2385	sporulation resulting in formation of a cellular spore
D9C18_13200	COG2247	cell wall binding repeat
D9C18_13205	COG2247	cell wall binding repeat
D9C18_13205	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C18_13220	COG2244	polysaccharide biosynthetic process
D9C18_13225	COG0297	glycogen (starch) synthase activity
D9C18_13225	COG0438	transferase activity, transferring glycosyl groups
D9C18_13230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C18_13240	COG3307	-O-antigen
D9C18_13245	COG3206	protein involved in exopolysaccharide biosynthesis
D9C18_13250	COG1215	transferase activity, transferring glycosyl groups
D9C18_13255	COG0438	transferase activity, transferring glycosyl groups
D9C18_13260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C18_13270	COG1131	(ABC) transporter
D9C18_13305	COG1316	TRANSCRIPTIONal
D9C18_13310	COG1739	Uncharacterized protein family UPF0029
D9C18_13315	COG4585	Histidine kinase
D9C18_13320	COG2197	response regulator
D9C18_13325	COG1307	EDD domain protein, DegV family
D9C18_13330	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9C18_13340	COG1040	competence protein
D9C18_13350	COG2747	anti-sigma28 factor FlgM
D9C18_13355	COG3418	PFAM FlgN family protein
D9C18_13360	COG1256	bacterial-type flagellum assembly
D9C18_13360	COG4786	Flagellar basal body rod
D9C18_13365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C18_13375	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9C18_13380	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9C18_13385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C18_13390	COG1334	flagellar protein FlaG
D9C18_13395	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9C18_13400	COG1516	flagellar protein fliS
D9C18_13415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9C18_13420	COG0653	protein targeting
D9C18_13430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C18_13435	COG2010	Cytochrome c
D9C18_13440	COG2884	Cell division ATP-binding protein ftsE
D9C18_13445	COG2177	Part of the ABC transporter FtsEX involved in
D9C18_13450	COG0793	Belongs to the peptidase S41A family
D9C18_13450	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_13460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C18_13465	COG2814	Major facilitator Superfamily
D9C18_13470	COG1309	transcriptional regulator
D9C18_13475	COG3848	Pyruvate phosphate dikinase
D9C18_13475	COG0574	Belongs to the PEP-utilizing enzyme family
D9C18_13480	COG4897	Protein conserved in bacteria
D9C18_13485	COG0556	nucleotide-excision repair
D9C18_13490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9C18_13495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C18_13510	COG3595	metallopeptidase activity
D9C18_13515	COG1983	PspC domain protein
D9C18_13520	COG1950	PFAM Membrane protein of
D9C18_13535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9C18_13545	COG0363	glucosamine-6-phosphate deaminase activity
D9C18_13550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9C18_13555	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9C18_13560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9C18_13565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9C18_13570	COG0546	phosphoglycolate phosphatase activity
D9C18_13585	COG5297	Belongs to the glycosyl hydrolase family 6
D9C18_13590	COG4990	cell redox homeostasis
D9C18_13595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9C18_13600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9C18_13605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9C18_13610	COG0131	Imidazoleglycerol-phosphate dehydratase
D9C18_13615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9C18_13620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9C18_13625	COG0107	imidazoleglycerol-phosphate synthase activity
D9C18_13630	COG0140	phosphoribosyl-ATP diphosphatase activity
D9C18_13630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9C18_13650	COG1132	(ABC) transporter
D9C18_13655	COG0457	Tetratricopeptide repeat
D9C18_13660	COG3883	PFAM NLP P60 protein
D9C18_13660	COG0791	NLP P60 protein
D9C18_13665	COG0492	ferredoxin-NADP+ reductase activity
D9C18_13670	COG1051	belongs to the nudix hydrolase family
D9C18_13675	COG1660	Displays ATPase and GTPase activities
D9C18_13680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9C18_13685	COG1481	regulation of sporulation
D9C18_13690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_13695	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9C18_13705	COG0745	RESPONSE REGULATOR receiver
D9C18_13710	COG5002	protein histidine kinase activity
D9C18_13715	COG1136	(ABC) transporter
D9C18_13720	COG0577	efflux transmembrane transporter activity
D9C18_13725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C18_13730	COG0288	reversible hydration of carbon dioxide
D9C18_13735	COG0659	secondary active sulfate transmembrane transporter activity
D9C18_13745	COG1611	Belongs to the LOG family
D9C18_13750	COG1609	Transcriptional regulator
D9C18_13760	COG2182	Extracellular solute-binding protein
D9C18_13765	COG1175	transmembrane transport
D9C18_13770	COG3833	ABC-type maltose transport systems, permease component
D9C18_13775	COG5521	maltodextrose utilization protein MalA
D9C18_13780	COG1554	hydrolase, family 65, central catalytic
D9C18_13785	COG0366	Alpha amylase catalytic
D9C18_13790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C18_13795	COG0740	serine-type endopeptidase activity
D9C18_13805	COG4974	Belongs to the 'phage' integrase family
D9C18_13905	COG0582	viral genome integration into host DNA
D9C18_13985	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C18_14020	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C18_14020	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_14020	COG1388	LysM domain
D9C18_14040	COG1674	ftsk spoiiie
D9C18_14060	COG2076	Multidrug Resistance protein
D9C18_14065	COG2076	Multidrug Resistance protein
D9C18_14070	COG1309	transcriptional regulator
D9C18_14075	COG0531	amino acid
D9C18_14080	COG1621	beta-fructofuranosidase activity
D9C18_14085	COG1621	beta-fructofuranosidase activity
D9C18_14095	COG1794	racemase activity, acting on amino acids and derivatives
D9C18_14110	COG3479	Phenolic acid decarboxylase
D9C18_14120	COG2272	Belongs to the type-B carboxylesterase lipase family
D9C18_14125	COG1396	sequence-specific DNA binding
D9C18_14130	COG3944	biosynthesis protein
D9C18_14135	COG0489	protein tyrosine kinase activity
D9C18_14140	COG1086	Polysaccharide biosynthesis protein
D9C18_14145	COG0438	transferase activity, transferring glycosyl groups
D9C18_14150	COG1215	transferase activity, transferring glycosyl groups
D9C18_14155	COG0438	transferase activity, transferring glycosyl groups
D9C18_14165	COG1216	Glycosyl transferase, family 2
D9C18_14170	COG5039	Polysaccharide pyruvyl transferase
D9C18_14175	COG1216	Glycosyl transferase, family 2
D9C18_14180	COG2244	polysaccharide biosynthetic process
D9C18_14185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9C18_14190	COG0110	maltose O-acetyltransferase activity
D9C18_14195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C18_14200	COG5039	Polysaccharide pyruvyl transferase
D9C18_14210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9C18_14215	COG1620	l-lactate permease
D9C18_14220	COG2186	Transcriptional regulator
D9C18_14225	COG1609	Transcriptional regulator
D9C18_14230	COG2182	Extracellular solute-binding protein
D9C18_14235	COG1175	transmembrane transport
D9C18_14240	COG3833	ABC-type maltose transport systems, permease component
D9C18_14245	COG1874	Beta-galactosidase
D9C18_14250	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9C18_14255	COG2208	phosphoserine phosphatase activity
D9C18_14260	COG0596	Alpha beta hydrolase
D9C18_14280	COG1131	(ABC) transporter
D9C18_14285	COG0842	Transport permease protein
D9C18_14290	COG4585	Histidine kinase
D9C18_14295	COG2197	response regulator
D9C18_14300	COG0247	lactate metabolic process
D9C18_14305	COG1139	Iron-sulfur cluster binding protein
D9C18_14310	COG1556	Lactate utilization protein
D9C18_14320	COG1113	amino acid transport
D9C18_14325	COG0697	spore germination
D9C18_14330	COG0583	DNA-binding transcription factor activity
D9C18_14340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C18_14345	COG1609	Transcriptional regulator
D9C18_14350	COG2814	Major facilitator Superfamily
D9C18_14355	COG2390	Transcriptional regulator
D9C18_14360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C18_14365	COG0126	phosphoglycerate kinase activity
D9C18_14370	COG0149	triose-phosphate isomerase activity
D9C18_14375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9C18_14380	COG0148	phosphopyruvate hydratase activity
D9C18_14385	COG0456	acetyltransferase
D9C18_14390	COG4640	response to antibiotic
D9C18_14395	COG3064	Membrane
D9C18_14405	COG2095	MarC family integral membrane protein
D9C18_14410	COG1510	regulation of RNA biosynthetic process
D9C18_14415	COG0517	IMP dehydrogenase activity
D9C18_14415	COG1125	glycine betaine transport
D9C18_14420	COG1174	glycine betaine transport
D9C18_14425	COG1732	Glycine betaine
D9C18_14430	COG1174	glycine betaine transport
D9C18_14435	COG1510	regulation of RNA biosynthetic process
D9C18_14445	COG1174	glycine betaine transport
D9C18_14450	COG1732	Glycine betaine
D9C18_14455	COG1174	glycine betaine transport
D9C18_14460	COG0840	transmembrane signaling receptor activity
D9C18_14465	COG1733	regulation of RNA biosynthetic process
D9C18_14470	COG1396	sequence-specific DNA binding
D9C18_14475	COG1396	sequence-specific DNA binding
D9C18_14480	COG1476	TRANSCRIPTIONal
D9C18_14485	COG0596	Alpha beta hydrolase
D9C18_14490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C18_14495	COG1647	Serine aminopeptidase, S33
D9C18_14500	COG0557	exoribonuclease II activity
D9C18_14505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9C18_14730	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C18_14730	COG3942	CHAP domain
D9C18_14755	COG4824	toxin secretion phage lysis holin
D9C18_14760	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C18_14760	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_14775	COG5444	nuclease activity
D9C18_14785	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_14790	COG1309	transcriptional regulator
D9C18_14795	COG2076	Multidrug Resistance protein
D9C18_14805	COG1289	transmembrane transporter activity
D9C18_14815	COG0673	inositol 2-dehydrogenase activity
D9C18_14820	COG1937	Protein conserved in bacteria
D9C18_14825	COG2608	mercury ion transmembrane transporter activity
D9C18_14830	COG2217	Heavy metal translocating P-type atpase
D9C18_14835	COG2217	Heavy metal translocating P-type atpase
D9C18_14840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9C18_14845	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9C18_14850	COG2860	membrane
D9C18_14860	COG3973	AAA domain
D9C18_14865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C18_14870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C18_14875	COG0025	NhaP-type Na H and K H
D9C18_14885	COG0656	L-ascorbic acid biosynthetic process
D9C18_14890	COG4149	molybdate abc transporter
D9C18_14895	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9C18_14900	COG1910	domain protein
D9C18_14905	COG1368	sulfuric ester hydrolase activity
D9C18_14910	COG1988	membrane-bound metal-dependent
D9C18_14925	COG0531	amino acid
D9C18_14935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C18_14940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_14945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_14950	COG1120	ATPase activity
D9C18_14955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C18_14960	COG1136	(ABC) transporter
D9C18_14965	COG0577	efflux transmembrane transporter activity
D9C18_14975	COG2140	Oxalate decarboxylase
D9C18_14995	COG0745	RESPONSE REGULATOR receiver
D9C18_15000	COG2205	protein histidine kinase activity
D9C18_15005	COG3386	PFAM SMP-30 Gluconolaconase
D9C18_15010	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_15015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C18_15020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C18_15025	COG1120	ATPase activity
D9C18_15030	COG2096	Adenosyltransferase
D9C18_15035	COG2814	Major facilitator Superfamily
D9C18_15040	COG4758	membrane
D9C18_15045	COG1842	Phage shock protein A
D9C18_15050	COG3595	metallopeptidase activity
D9C18_15055	COG4758	membrane
D9C18_15060	COG4585	Histidine kinase
D9C18_15065	COG2197	response regulator
D9C18_15075	COG0814	amino acid
D9C18_15080	COG0697	spore germination
D9C18_15090	COG0114	fumarate hydratase activity
D9C18_15095	COG1309	transcriptional regulator
D9C18_15105	COG2205	protein histidine kinase activity
D9C18_15105	COG2770	Histidine kinase
D9C18_15110	COG0745	RESPONSE REGULATOR receiver
D9C18_15115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C18_15120	COG0783	Belongs to the Dps family
D9C18_15170	COG1131	(ABC) transporter
D9C18_15190	COG1120	ATPase activity
D9C18_15200	COG0583	DNA-binding transcription factor activity
D9C18_15205	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_15210	COG1942	4-Oxalocrotonate Tautomerase
D9C18_15215	COG0477	Major facilitator Superfamily
D9C18_15220	COG1846	Transcriptional regulator
D9C18_15225	COG5577	PFAM Coat F domain
D9C18_15245	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C18_15245	COG1024	Enoyl-CoA hydratase
D9C18_15250	COG0183	Belongs to the thiolase family
D9C18_15255	COG1960	acyl-CoA dehydrogenase activity
D9C18_15260	COG1393	Belongs to the ArsC family
D9C18_15265	COG0509	glycine decarboxylation via glycine cleavage system
D9C18_15275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C18_15280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_15290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9C18_15295	COG2011	ABC-type metal ion transport system permease component
D9C18_15300	COG1464	Belongs to the NlpA lipoprotein family
D9C18_15320	COG0396	ATPase activity
D9C18_15325	COG0719	Fe-S assembly protein
D9C18_15330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C18_15335	COG0822	iron-sulfur transferase activity
D9C18_15340	COG0719	Fe-S assembly protein
D9C18_15345	COG0640	Transcriptional regulator
D9C18_15350	COG0346	lactoylglutathione lyase activity
D9C18_15365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C18_15370	COG0322	excinuclease ABC activity
D9C18_15375	COG2222	sugar isomerase
D9C18_15380	COG1653	transport
D9C18_15385	COG1175	transmembrane transport
D9C18_15395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C18_15400	COG2188	Transcriptional regulator
D9C18_15405	COG3842	ATPase activity
D9C18_15410	COG2356	endonuclease I
D9C18_15420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C18_15425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9C18_15430	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9C18_15435	COG2068	MobA-Related Protein
D9C18_15440	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9C18_15445	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9C18_15450	COG2080	2 iron, 2 sulfur cluster binding
D9C18_15460	COG2351	hydroxyisourate hydrolase activity
D9C18_15465	COG3195	allantoin biosynthetic process
D9C18_15465	COG3648	Uricase
D9C18_15470	COG2233	PERMEase
D9C18_15475	COG2233	PERMEase
D9C18_15480	COG2508	Transcriptional regulator
D9C18_15485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C18_15495	COG1801	Protein of unknown function DUF72
D9C18_15500	COG0730	response to heat
D9C18_15505	COG0737	Belongs to the 5'-nucleotidase family
D9C18_15510	COG3377	Domain of unknown function (DUF1805)
D9C18_15520	COG0739	heme binding
D9C18_15525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9C18_15535	COG4470	Protein conserved in bacteria
D9C18_15540	COG2445	Protein of unknown function DUF86
D9C18_15545	COG0647	UMP catabolic process
D9C18_15550	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C18_15555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C18_15560	COG0460	homoserine dehydrogenase
D9C18_15565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9C18_15570	COG0083	homoserine kinase activity
D9C18_15575	COG1506	peptidase
D9C18_15575	COG4946	Tricorn protease homolog
D9C18_15575	COG0823	Involved in the tonB-independent uptake of proteins
D9C18_15580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9C18_15585	COG4837	Protein of unknown function (DUF1462)
D9C18_15590	COG1252	NADH dehydrogenase
D9C18_15595	COG4844	belongs to the
D9C18_15600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C18_15605	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9C18_15610	COG0316	Belongs to the HesB IscA family
D9C18_15615	COG4974	Belongs to the 'phage' integrase family
D9C18_15625	COG0582	viral genome integration into host DNA
D9C18_15725	COG0456	acetyltransferase
D9C18_15730	COG2808	Putative FMN-binding domain
D9C18_15735	COG0516	GMP reductase activity
D9C18_15745	COG0492	ferredoxin-NADP+ reductase activity
D9C18_15750	COG1252	NADH dehydrogenase
D9C18_15765	COG3584	3D domain protein
D9C18_15770	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9C18_15775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9C18_15780	COG2056	Na+-H+ antiporter family
D9C18_15785	COG1268	BioY protein
D9C18_15790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C18_15795	COG2819	hydrolase of the alpha beta superfamily
D9C18_15800	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_15805	COG1169	isochorismate synthase
D9C18_15810	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9C18_15815	COG3433	isochorismatase activity
D9C18_15815	COG1535	isochorismatase
D9C18_15820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C18_15825	COG3251	PFAM MbtH domain protein
D9C18_15830	COG5634	Uncharacterized conserved protein (DUF2278)
D9C18_15835	COG0686	Belongs to the AlaDH PNT family
D9C18_15840	COG2508	Transcriptional regulator
D9C18_15840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C18_15850	COG4842	Belongs to the WXG100 family
D9C18_15855	COG5417	Belongs to the EsaB family
D9C18_15860	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C18_15865	COG1674	ftsk spoiiie
D9C18_15865	COG0433	COG0433 Predicted ATPase
D9C18_15870	COG1511	domain protein
D9C18_15880	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_15885	COG1418	mRNA catabolic process
D9C18_15900	COG0628	permease
D9C18_15915	COG5506	Protein of unknown function (DUF1694)
D9C18_15920	COG1335	isochorismatase
D9C18_15925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9C18_15930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9C18_15950	COG0142	geranyltranstransferase activity
D9C18_15960	COG4585	Histidine kinase
D9C18_15965	COG2197	response regulator
D9C18_15970	COG2050	protein possibly involved in aromatic compounds catabolism
D9C18_15975	COG1320	monovalent cation:proton antiporter activity
D9C18_15980	COG2212	antiporter activity
D9C18_15985	COG1863	multisubunit Na H antiporter MnhE subunit
D9C18_15990	COG0651	ATP synthesis coupled electron transport
D9C18_15995	COG1006	Multisubunit Na H antiporter MnhC subunit
D9C18_16000	COG2111	Na H antiporter
D9C18_16005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C18_16005	COG2111	Na H antiporter
D9C18_16015	COG3493	citrate carrier protein
D9C18_16040	COG4565	transcriptional regulatory protein
D9C18_16045	COG3290	protein histidine kinase activity
D9C18_16055	COG3011	Protein conserved in bacteria
D9C18_16060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C18_16065	COG2814	Major facilitator Superfamily
D9C18_16075	COG5018	Exonuclease
D9C18_16085	COG2205	protein histidine kinase activity
D9C18_16090	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9C18_16100	COG2267	carboxylic ester hydrolase activity
D9C18_16105	COG1522	sequence-specific DNA binding
D9C18_16110	COG0436	Aminotransferase
D9C18_16115	COG1098	S1 RNA binding domain
D9C18_16120	COG2155	Conserved Protein
D9C18_16125	COG1979	alcohol dehydrogenase
D9C18_16130	COG1979	alcohol dehydrogenase
D9C18_16135	COG0166	Belongs to the GPI family
D9C18_16150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9C18_16165	COG2738	Putative neutral zinc metallopeptidase
D9C18_16170	COG1253	flavin adenine dinucleotide binding
D9C18_16175	COG0366	Alpha amylase catalytic
D9C18_16185	COG0432	Pfam Uncharacterised protein family UPF0047
D9C18_16200	COG0840	transmembrane signaling receptor activity
D9C18_16210	COG0840	transmembrane signaling receptor activity
D9C18_16225	COG3347	Dehydrogenase
D9C18_16225	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_16230	COG1349	DNA-binding transcription factor activity
D9C18_16235	COG1070	Carbohydrate kinase
D9C18_16240	COG3254	rhamnose metabolic process
D9C18_16245	COG4806	L-rhamnose isomerase
D9C18_16250	COG0673	inositol 2-dehydrogenase activity
D9C18_16255	COG0628	permease
D9C18_16260	COG1968	undecaprenyl-diphosphatase activity
D9C18_16270	COG5553	Cysteine dioxygenase type I
D9C18_16275	COG0477	Major facilitator Superfamily
D9C18_16280	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C18_16285	COG4682	membrane
D9C18_16290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C18_16295	COG0569	domain protein
D9C18_16305	COG1510	regulation of RNA biosynthetic process
D9C18_16315	COG1454	alcohol dehydrogenase
D9C18_16325	COG2318	DinB family
D9C18_16330	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9C18_16335	COG2268	Band 7 protein
D9C18_16340	COG1247	-acetyltransferase
D9C18_16345	COG3859	Proton-coupled thiamine transporter YuaJ
D9C18_16470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9C18_16475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C18_16480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C18_16485	COG0297	glycogen (starch) synthase activity
D9C18_16490	COG0058	SHG alpha-glucan phosphorylase activity
D9C18_16495	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9C18_16500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C18_16505	COG0438	transferase activity, transferring glycosyl groups
D9C18_16510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C18_16520	COG0438	transferase activity, transferring glycosyl groups
D9C18_16525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C18_16530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C18_16535	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C18_16540	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C18_16545	COG1169	isochorismate synthase
D9C18_16550	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9C18_16555	COG0596	Alpha beta hydrolase
D9C18_16560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9C18_16565	COG0318	PFAM AMP-dependent synthetase and ligase
D9C18_16570	COG4948	Mandelate Racemase Muconate Lactonizing
D9C18_16575	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C18_16580	COG1121	(ABC) transporter
D9C18_16585	COG1321	iron dependent repressor
D9C18_16585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C18_16590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C18_16600	COG1294	oxidase, subunit
D9C18_16605	COG1271	oxidase subunit
D9C18_16610	COG0254	rRNA binding
D9C18_16615	COG0288	reversible hydration of carbon dioxide
D9C18_16620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9C18_16625	COG1854	S-ribosylhomocysteine lyase activity
D9C18_16640	COG0783	Belongs to the Dps family
D9C18_16645	COG4824	toxin secretion phage lysis holin
D9C18_16650	COG0494	nUDIX hydrolase
D9C18_16655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C18_16660	COG1116	anion transmembrane transporter activity
D9C18_16665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C18_16670	COG1506	peptidase
D9C18_16680	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9C18_16685	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9C18_16690	COG0367	asparagine synthase
D9C18_16695	COG1113	amino acid transport
D9C18_16700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9C18_16705	COG2267	carboxylic ester hydrolase activity
D9C18_16715	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9C18_16720	COG1242	4 iron, 4 sulfur cluster binding
D9C18_16735	COG1725	Transcriptional regulator
D9C18_16740	COG1131	(ABC) transporter
D9C18_16755	COG1136	(ABC) transporter
D9C18_16760	COG0577	efflux transmembrane transporter activity
D9C18_16765	COG0745	RESPONSE REGULATOR receiver
D9C18_16770	COG2205	protein histidine kinase activity
D9C18_16775	COG1136	(ABC) transporter
D9C18_16780	COG0577	efflux transmembrane transporter activity
D9C18_16785	COG2433	Pfam Transposase IS66
D9C18_16790	COG2814	Major facilitator Superfamily
D9C18_16795	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_16795	COG2202	Pas domain
D9C18_16805	COG0495	leucyl-tRNA aminoacylation
D9C18_16810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C18_16815	COG1486	melibiose metabolic process
D9C18_16840	COG1073	alpha beta
D9C18_16850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C18_16870	COG2124	cytochrome p450
D9C18_16875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C18_16880	COG0395	ABC-type sugar transport system, permease component
D9C18_16885	COG1653	transport
D9C18_16895	COG4209	transmembrane transport
D9C18_16900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C18_16905	COG1653	transport
D9C18_16925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9C18_16930	COG2081	HI0933 family
D9C18_16935	COG2244	polysaccharide biosynthetic process
D9C18_16940	COG1187	pseudouridine synthase activity
D9C18_16945	COG1349	DNA-binding transcription factor activity
D9C18_16950	COG1131	(ABC) transporter
D9C18_16955	COG4473	ABC transporter
D9C18_16960	COG2252	PERMEase
D9C18_16965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C18_16970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C18_16975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C18_16985	COG1597	lipid kinase activity
D9C18_16990	COG1523	belongs to the glycosyl hydrolase 13 family
D9C18_16995	COG0510	thiamine kinase activity
D9C18_17005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9C18_17010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C18_17015	COG0281	malic enzyme
D9C18_17020	COG5584	Small secreted protein
D9C18_17025	COG1363	Peptidase, m42
D9C18_17040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_17045	COG4848	Belongs to the UPF0354 family
D9C18_17050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C18_17055	COG1674	ftsk spoiiie
D9C18_17060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9C18_17065	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C18_17070	COG4980	gas vesicle protein
D9C18_17075	COG3118	belongs to the thioredoxin family
D9C18_17080	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9C18_17080	COG1605	Chorismate mutase
D9C18_17085	COG1609	Transcriptional regulator
D9C18_17090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C18_17095	COG1360	Flagellar Motor Protein
D9C18_17100	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9C18_17105	COG0517	IMP dehydrogenase activity
D9C18_17110	COG0454	-acetyltransferase
D9C18_17115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C18_17120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C18_17125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9C18_17135	COG2203	Gaf domain
D9C18_17135	COG2199	diguanylate cyclase activity
D9C18_17140	COG1956	GAF domain-containing protein
D9C18_17145	COG1309	transcriptional regulator
D9C18_17150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C18_17155	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9C18_17160	COG1114	Component of the transport system for branched-chain amino acids
D9C18_17165	COG1104	cysteine desulfurase activity
D9C18_17170	COG0301	tRNA thio-modification
D9C18_17180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C18_17185	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9C18_17190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C18_17195	COG0616	signal peptide processing
D9C18_17200	COG1714	RDD family
D9C18_17210	COG3874	Sporulation protein YtfJ
D9C18_17215	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9C18_17220	COG0827	DNA restriction-modification system
D9C18_17230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9C18_17235	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9C18_17240	COG0137	argininosuccinate synthase activity
D9C18_17245	COG0165	Argininosuccinate lyase
D9C18_17255	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_17260	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9C18_17270	COG4109	DRTGG domain
D9C18_17280	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9C18_17300	COG0587	DNA-directed DNA polymerase activity
D9C18_17305	COG0281	malic enzyme
D9C18_17310	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9C18_17315	COG0825	malonyl-CoA metabolic process
D9C18_17320	COG0205	6-phosphofructokinase activity
D9C18_17325	COG0469	pyruvate kinase activity
D9C18_17330	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9C18_17335	COG0628	permease
D9C18_17340	COG2707	UPF0756 membrane protein
D9C18_17345	COG0372	Belongs to the citrate synthase family
D9C18_17350	COG0538	isocitrate dehydrogenase activity
D9C18_17355	COG0039	L-malate dehydrogenase activity
D9C18_17360	COG0745	RESPONSE REGULATOR receiver
D9C18_17365	COG5002	protein histidine kinase activity
D9C18_17370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C18_17370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C18_17375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9C18_17380	COG1971	Probably functions as a manganese efflux pump
D9C18_17385	COG0237	dephospho-CoA kinase activity
D9C18_17390	COG0656	L-ascorbic acid biosynthetic process
D9C18_17395	COG2814	Major facilitator Superfamily
D9C18_17400	COG1733	regulation of RNA biosynthetic process
D9C18_17405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C18_17410	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9C18_17415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9C18_17420	COG3611	Membrane attachment protein
D9C18_17425	COG1484	DNA-dependent DNA replication
D9C18_17430	COG0398	Pfam SNARE associated Golgi protein
D9C18_17440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C18_17450	COG3275	phosphorelay sensor kinase activity
D9C18_17455	COG3279	Response regulator of the LytR AlgR family
D9C18_17460	COG1380	Effector of murein hydrolase LrgA
D9C18_17465	COG1346	cytolysis
D9C18_17475	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9C18_17480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9C18_17485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9C18_17490	COG3326	Membrane
D9C18_17500	COG1363	Peptidase, m42
D9C18_17510	COG2160	L-arabinose isomerase activity
D9C18_17515	COG1069	ribulokinase activity
D9C18_17520	COG0235	Class ii aldolase
D9C18_17525	COG0647	UMP catabolic process
D9C18_17530	COG0371	Dehydrogenase
D9C18_17535	COG1653	transport
D9C18_17540	COG1175	transmembrane transport
D9C18_17545	COG0395	ABC-type sugar transport system, permease component
D9C18_17550	COG3534	alpha-L-arabinofuranosidase
D9C18_17555	COG1966	Carbon starvation protein
D9C18_17560	COG0346	lactoylglutathione lyase activity
D9C18_17565	COG0247	lactate metabolic process
D9C18_17570	COG0277	FAD linked oxidase domain protein
D9C18_17575	COG3835	regulator
D9C18_17585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C18_17595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9C18_17600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C18_17600	COG0072	phenylalanine-tRNA ligase activity
D9C18_17605	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C18_17610	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9C18_17615	COG1286	toxin biosynthetic process
D9C18_17620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C18_17620	COG1796	DNA polymerase
D9C18_17625	COG1193	negative regulation of DNA recombination
D9C18_17630	COG3766	membrane
D9C18_17635	COG0318	PFAM AMP-dependent synthetase and ligase
D9C18_17640	COG1309	transcriptional regulator
D9C18_17645	COG1024	Enoyl-CoA hydratase
D9C18_17650	COG2086	electron transfer activity
D9C18_17655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9C18_17660	COG3534	alpha-L-arabinofuranosidase
D9C18_17665	COG3118	belongs to the thioredoxin family
D9C18_17670	COG0322	excinuclease ABC activity
D9C18_17680	COG0527	aspartate kinase activity
D9C18_17685	COG1719	4-vinyl reductase, 4VR
D9C18_17690	COG2009	succinate dehydrogenase
D9C18_17695	COG1053	succinate dehydrogenase
D9C18_17700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9C18_17705	COG0824	Thioesterase
D9C18_17710	COG2197	response regulator
D9C18_17715	COG1846	Transcriptional regulator
D9C18_17720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C18_17725	COG5401	PFAM Sporulation and spore germination
D9C18_17730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9C18_17735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9C18_17740	COG0622	Phosphoesterase
D9C18_17765	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
D9C18_17795	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D9C18_17810	COG0028	Belongs to the TPP enzyme family
D9C18_17815	COG0440	acetolactate synthase activity
D9C18_17820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9C18_17825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C18_17830	COG0473	3-isopropylmalate dehydrogenase activity
D9C18_17835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9C18_17840	COG0066	3-isopropylmalate dehydratase activity
D9C18_17845	COG0457	Tetratricopeptide repeat
D9C18_17845	COG1477	protein flavinylation
D9C18_17850	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9C18_17855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9C18_17860	COG0470	DNA polymerase III
D9C18_17860	COG1067	ATP-dependent peptidase activity
D9C18_17865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9C18_17870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9C18_17880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9C18_17885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C18_17890	COG0181	hydroxymethylbilane synthase activity
D9C18_17895	COG1587	Uroporphyrinogen-III synthase
D9C18_17900	COG0113	porphobilinogen synthase activity
D9C18_17905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C18_17910	COG1388	LysM domain
D9C18_17915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C18_17925	COG0525	valine-tRNA ligase activity
D9C18_17930	COG0285	dihydrofolate synthase activity
D9C18_17935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9C18_17945	COG0424	maF-like protein
D9C18_17950	COG2003	Belongs to the UPF0758 family
D9C18_17955	COG1077	Cell shape determining protein MreB Mrl
D9C18_17960	COG1792	Involved in formation and maintenance of cell shape
D9C18_17965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9C18_17970	COG0850	regulation of cytokinetic process
D9C18_17975	COG2894	cell division
D9C18_17980	COG0739	heme binding
D9C18_17985	COG1994	Peptidase M50
D9C18_17990	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9C18_17995	COG2868	ribosomal protein
D9C18_18000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9C18_18010	COG3290	protein histidine kinase activity
D9C18_18015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9C18_18020	COG4492	Belongs to the UPF0735 family
D9C18_18025	COG0077	Prephenate dehydratase
D9C18_18030	COG1827	regulation of RNA biosynthetic process
D9C18_18035	COG1104	cysteine desulfurase activity
D9C18_18040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9C18_18045	COG0157	Belongs to the NadC ModD family
D9C18_18050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9C18_18055	COG1388	LysM domain
D9C18_18065	COG0217	transcriptional regulatory protein
D9C18_18070	COG1115	amino acid carrier protein
D9C18_18090	COG2112	serine threonine protein kinase
D9C18_18095	COG0673	inositol 2-dehydrogenase activity
D9C18_18100	COG2814	Major facilitator Superfamily
D9C18_18110	COG0632	four-way junction helicase activity
D9C18_18115	COG2255	four-way junction helicase activity
D9C18_18125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9C18_18130	COG0343	queuine tRNA-ribosyltransferase activity
D9C18_18135	COG1862	Preprotein translocase
D9C18_18145	COG2323	membrane
D9C18_18150	COG2244	polysaccharide biosynthetic process
D9C18_18160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C18_18160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C18_18165	COG0490	domain, Protein
D9C18_18170	COG5416	Lipopolysaccharide assembly protein A domain
D9C18_18175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9C18_18175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9C18_18180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C18_18185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9C18_18190	COG1490	D-aminoacyl-tRNA deacylase activity
D9C18_18195	COG4991	sh3 domain protein
D9C18_18195	COG3103	Sh3 type 3 domain protein
D9C18_18195	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C18_18205	COG0124	histidyl-tRNA synthetase
D9C18_18210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9C18_18220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9C18_18225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9C18_18230	COG1959	2 iron, 2 sulfur cluster binding
D9C18_18235	COG1104	cysteine desulfurase activity
D9C18_18240	COG0482	sulfurtransferase activity
D9C18_18245	COG0457	Tetratricopeptide repeat
D9C18_18250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9C18_18255	COG3881	PFAM PRC-barrel domain
D9C18_18270	COG0765	amino acid transport
D9C18_18275	COG0765	amino acid transport
D9C18_18280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C18_18285	COG1126	abc transporter atp-binding protein
D9C18_18290	COG0628	permease
D9C18_18295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9C18_18300	COG4472	Bacterial protein of unknown function (DUF965)
D9C18_18305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9C18_18310	COG3906	Belongs to the UPF0473 family
D9C18_18315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C18_18335	COG0572	uridine kinase
D9C18_18340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9C18_18345	COG0768	penicillin binding
D9C18_18360	COG2226	methyltransferase
D9C18_18365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9C18_18370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C18_18375	COG0626	cystathionine gamma-synthase activity
D9C18_18390	COG2427	Protein of unknown function (DUF1641)
D9C18_18395	COG3383	formate dehydrogenase (NAD+) activity
D9C18_18400	COG5609	conserved protein (DUF2294)
D9C18_18405	COG2116	formate transmembrane transporter activity
D9C18_18420	COG2226	methyltransferase
D9C18_18425	COG1309	transcriptional regulator
D9C18_18450	COG1595	DNA-templated transcription, initiation
D9C18_18455	COG1378	Sugar-specific transcriptional regulator TrmB
D9C18_18460	COG1280	lysine exporter protein (LysE YggA)
D9C18_18465	COG1113	amino acid transport
D9C18_18475	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C18_18475	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D9C18_18480	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C18_18485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C18_18490	COG3715	PTS system
D9C18_18495	COG3716	PTS system mannose fructose sorbose family IID component
D9C18_18500	COG1621	beta-fructofuranosidase activity
D9C18_18505	COG0693	protein deglycase activity
D9C18_18510	COG1064	alcohol dehydrogenase
D9C18_18520	COG0789	Transcriptional regulator
D9C18_18525	COG5577	PFAM Coat F domain
D9C18_18535	COG1063	alcohol dehydrogenase
D9C18_18540	COG5577	PFAM Coat F domain
D9C18_18550	COG0346	lactoylglutathione lyase activity
D9C18_18560	COG4991	sh3 domain protein
D9C18_18565	COG4991	sh3 domain protein
D9C18_18575	COG5566	PFAM Mor transcription activator
D9C18_18580	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_18585	COG0667	Aldo Keto reductase
D9C18_18590	COG1595	DNA-templated transcription, initiation
D9C18_18595	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9C18_18615	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C18_18630	COG2070	2-Nitropropane dioxygenase
D9C18_18640	COG2318	DinB family
D9C18_18655	COG1335	isochorismatase
D9C18_18665	COG2124	cytochrome p450
D9C18_18670	COG2732	(Barnase) inhibitor
D9C18_18675	COG1522	sequence-specific DNA binding
D9C18_18685	COG1687	branched-chain amino acid
D9C18_18690	COG1114	Component of the transport system for branched-chain amino acids
D9C18_18700	COG1230	cation diffusion facilitator family transporter
D9C18_18705	COG2072	flavoprotein involved in K transport
D9C18_18710	COG0583	DNA-binding transcription factor activity
D9C18_18715	COG0697	spore germination
D9C18_18725	COG1253	flavin adenine dinucleotide binding
D9C18_18730	COG0456	acetyltransferase
D9C18_18735	COG2814	Major facilitator Superfamily
D9C18_18740	COG0789	Transcriptional regulator
D9C18_18740	COG4978	Transcriptional regulator
D9C18_18865	COG0457	Tetratricopeptide repeat
D9C18_18880	COG0583	DNA-binding transcription factor activity
D9C18_18885	COG0114	fumarate hydratase activity
D9C18_18905	COG3209	COG3209 Rhs family protein
D9C18_18915	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D9C18_18920	COG0398	Pfam SNARE associated Golgi protein
D9C18_18925	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_18925	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C18_18930	COG2755	lipolytic protein G-D-S-L family
D9C18_18940	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9C18_18945	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C18_18950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9C18_18955	COG1534	Rna-binding protein
D9C18_18960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9C18_18965	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9C18_18970	COG0799	negative regulation of ribosome biogenesis
D9C18_18975	COG2226	methyltransferase
D9C18_18980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C18_18985	COG1596	polysaccharide export
D9C18_18985	COG1555	photosystem II stabilization
D9C18_18990	COG2131	deaminase
D9C18_18995	COG2333	competence protein COMEC
D9C18_18995	COG0658	competence protein
D9C18_19010	COG1466	dna polymerase III delta subunit
D9C18_19015	COG0268	Binds directly to 16S ribosomal RNA
D9C18_19020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9C18_19025	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C18_19035	COG0481	GTPase activity
D9C18_19040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C18_19045	COG1420	regulation of RNA biosynthetic process
D9C18_19050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9C18_19055	COG0443	Heat shock 70 kDa protein
D9C18_19060	COG0484	heat shock protein binding
D9C18_19065	COG2264	protein methyltransferase activity
D9C18_19070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9C18_19075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C18_19080	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9C18_19085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9C18_19090	COG1610	YqeY-like protein
D9C18_19095	COG1030	water channel activity
D9C18_19100	COG4864	UPF0365 protein
D9C18_19115	COG0561	phosphatase activity
D9C18_19120	COG1702	phosphate starvation-inducible protein PhoH
D9C18_19125	COG1480	7TM receptor with intracellular HD hydrolase
D9C18_19130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9C18_19135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9C18_19140	COG0295	cytidine deaminase activity
D9C18_19145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9C18_19155	COG1381	Involved in DNA repair and RecF pathway recombination
D9C18_19160	COG0752	glycyl-tRNA synthetase alpha subunit
D9C18_19165	COG0751	glycine-tRNA ligase activity
D9C18_19170	COG0517	IMP dehydrogenase activity
D9C18_19175	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9C18_19180	COG1671	Belongs to the UPF0178 family
D9C18_19185	COG0358	DNA primase activity
D9C18_19190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9C18_19200	COG2010	Cytochrome c
D9C18_19205	COG2384	SAM-dependent methyltransferase
D9C18_19210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9C18_19215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9C18_19225	COG0513	Belongs to the DEAD box helicase family
D9C18_19230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9C18_19240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C18_19245	COG0735	belongs to the Fur family
D9C18_19250	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9C18_19255	COG4709	membrane
D9C18_19260	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9C18_19265	COG1388	LysM domain
D9C18_19270	COG5521	maltodextrose utilization protein MalA
D9C18_19275	COG2839	Protein conserved in bacteria
D9C18_19280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C18_19285	COG0477	Major facilitator Superfamily
D9C18_19295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9C18_19300	COG0573	inorganic phosphate transmembrane transporter activity
D9C18_19305	COG0581	inorganic phosphate transmembrane transporter activity
D9C18_19310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C18_19315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C18_19320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C18_19335	COG0438	transferase activity, transferring glycosyl groups
D9C18_19340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C18_19345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9C18_19355	COG0705	Rhomboid family
D9C18_19355	COG0457	Tetratricopeptide repeat
D9C18_19360	COG4483	Protein conserved in bacteria
D9C18_19365	COG1940	carbohydrate kinase activity
D9C18_19370	COG1368	sulfuric ester hydrolase activity
D9C18_19375	COG2866	Carboxypeptidase
D9C18_19385	COG0011	TIGRFAM Protein of
D9C18_19395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C18_19405	COG1393	Belongs to the ArsC family
D9C18_19415	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_19420	COG1253	flavin adenine dinucleotide binding
D9C18_19425	COG0598	Magnesium transport protein CorA
D9C18_19430	COG0517	IMP dehydrogenase activity
D9C18_19435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9C18_19440	COG1459	type II secretion system
D9C18_19445	COG4537	Required for transformation and DNA binding
D9C18_19450	COG4970	Tfp pilus assembly protein FimT
D9C18_19460	COG4940	Competence protein ComGF
D9C18_19485	COG0681	Belongs to the peptidase S26 family
D9C18_19495	COG1396	sequence-specific DNA binding
D9C18_19510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C18_19515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9C18_19520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C18_19525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C18_19530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C18_19535	COG0095	Lipoate-protein ligase
D9C18_19540	COG1321	iron dependent repressor
D9C18_19545	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C18_19555	COG3872	metal-dependent enzyme
D9C18_19565	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9C18_19570	COG0006	proline dipeptidase activity
D9C18_19575	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9C18_19585	COG3854	ATPases associated with a variety of cellular activities
D9C18_19630	COG0511	ligase activity, forming carbon-carbon bonds
D9C18_19635	COG0439	Biotin carboxylase
D9C18_19640	COG1302	Protein conserved in bacteria
D9C18_19645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C18_19650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9C18_19655	COG1570	exodeoxyribonuclease VII activity
D9C18_19660	COG1722	exodeoxyribonuclease VII activity
D9C18_19665	COG0142	geranyltranstransferase activity
D9C18_19670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9C18_19675	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9C18_19680	COG1438	arginine binding
D9C18_19685	COG0497	DNA recombination
D9C18_19690	COG0750	zinc metalloprotease
D9C18_19700	COG0745	RESPONSE REGULATOR receiver
D9C18_19705	COG1902	pentaerythritol trinitrate reductase activity
D9C18_19720	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C18_19725	COG0584	glycerophosphoryl diester phosphodiesterase
D9C18_19730	COG0183	Belongs to the thiolase family
D9C18_19735	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C18_19740	COG1960	acyl-CoA dehydrogenase activity
D9C18_19745	COG0372	Belongs to the citrate synthase family
D9C18_19750	COG2079	MmgE PrpD family protein
D9C18_19755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9C18_19765	COG3829	transcription factor binding
D9C18_19765	COG3290	protein histidine kinase activity
D9C18_19770	COG0280	phosphate acetyltransferase
D9C18_19775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C18_19780	COG3426	butyrate kinase activity
D9C18_19785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C18_19790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C18_19795	COG0022	dehydrogenase e1 component
D9C18_19800	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C18_19805	COG0789	Transcriptional regulator
D9C18_19805	COG4978	Transcriptional regulator
D9C18_19815	COG1597	lipid kinase activity
D9C18_19825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C18_19830	COG0765	amino acid transport
D9C18_19835	COG1126	abc transporter atp-binding protein
D9C18_19840	COG4129	membrane
D9C18_19845	COG1376	ErfK ybiS ycfS ynhG family protein
D9C18_19850	COG0346	lactoylglutathione lyase activity
D9C18_19860	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C18_19870	COG0706	membrane insertase activity
D9C18_19880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C18_19885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C18_19890	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9C18_19895	COG1234	tRNA 3'-trailer cleavage
D9C18_19905	COG0596	Alpha beta hydrolase
D9C18_19920	COG1902	pentaerythritol trinitrate reductase activity
D9C18_19925	COG4187	Peptidase family M20/M25/M40
D9C18_19930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C18_19935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C18_19940	COG0300	oxidoreductase activity
D9C18_19945	COG3048	D-serine ammonia-lyase activity
D9C18_19950	COG1072	(Pantothenic acid kinase))
D9C18_19955	COG0346	lactoylglutathione lyase activity
D9C18_19960	COG2211	Major facilitator Superfamily
D9C18_19970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C18_19980	COG0456	acetyltransferase
D9C18_19985	COG2329	Antibiotic biosynthesis monooxygenase
D9C18_19990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9C18_19990	COG0456	acetyltransferase
D9C18_19995	COG4918	Iron-sulphur cluster biosynthesis
D9C18_20005	COG1073	alpha beta
D9C18_20015	COG0667	Aldo Keto reductase
D9C18_20025	COG0494	nUDIX hydrolase
D9C18_20030	COG1379	DNA repair
D9C18_20035	COG1396	sequence-specific DNA binding
D9C18_20040	COG0252	asparaginase activity
D9C18_20045	COG1027	Aspartate ammonia-lyase
D9C18_20050	COG1757	Na H antiporter
D9C18_20055	COG0281	malic enzyme
D9C18_20065	COG1300	Membrane
D9C18_20070	COG0735	belongs to the Fur family
D9C18_20080	COG4974	Belongs to the 'phage' integrase family
D9C18_20085	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9C18_20090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9C18_20095	COG1686	Belongs to the peptidase S11 family
D9C18_20100	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_20105	COG2172	sigma factor antagonist activity
D9C18_20110	COG1191	sigma factor activity
D9C18_20145	COG0697	spore germination
D9C18_20150	COG0019	diaminopimelate decarboxylase activity
D9C18_20155	COG4086	secreted protein
D9C18_20170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9C18_20225	COG3328	transposase activity
D9C18_20275	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9C18_20285	COG0681	Belongs to the peptidase S26 family
D9C18_20295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C18_20295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C18_20300	COG0307	riboflavin synthase, alpha
D9C18_20305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C18_20305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C18_20310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9C18_20315	COG0456	acetyltransferase
D9C18_20320	COG1547	Domain of unknown function (DUF309)
D9C18_20325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9C18_20330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9C18_20340	COG1686	Belongs to the peptidase S11 family
D9C18_20345	COG2715	membrane protein required for spore maturation
D9C18_20350	COG0700	Nucleoside recognition
D9C18_20355	COG1187	pseudouridine synthase activity
D9C18_20360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_20365	COG1333	cytochrome c biogenesis protein
D9C18_20370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C18_20375	COG0745	RESPONSE REGULATOR receiver
D9C18_20380	COG5002	protein histidine kinase activity
D9C18_20385	COG1595	DNA-templated transcription, initiation
D9C18_20395	COG0710	3-dehydroquinate dehydratase activity
D9C18_20400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C18_20405	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9C18_20410	COG1141	Ferredoxin
D9C18_20415	COG4955	Helix-turn-helix domain
D9C18_20420	COG0514	ATP-dependent DNA helicase (RecQ)
D9C18_20425	COG1266	CAAX protease self-immunity
D9C18_20430	COG1388	LysM domain
D9C18_20440	COG1408	metallophosphoesterase
D9C18_20445	COG4862	establishment of competence for transformation
D9C18_20450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C18_20455	COG0492	ferredoxin-NADP+ reductase activity
D9C18_20460	COG2339	peptidase activity
D9C18_20465	COG3773	Cell wall hydrolase
D9C18_20465	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_20470	COG2959	enzyme of heme biosynthesis
D9C18_20475	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9C18_20485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9C18_20490	COG0539	negative regulation of cytoplasmic translation
D9C18_20495	COG1304	FMN binding
D9C18_20520	COG1160	GTP binding
D9C18_20525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9C18_20540	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C18_20545	COG0776	regulation of translation
D9C18_20550	COG0302	gtp cyclohydrolase
D9C18_20560	COG0142	geranyltranstransferase activity
D9C18_20565	COG2226	methyltransferase
D9C18_20570	COG0142	geranyltranstransferase activity
D9C18_20575	COG0105	UTP biosynthetic process
D9C18_20580	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9C18_20585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9C18_20590	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9C18_20595	COG4401	Chorismate mutase type I
D9C18_20600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C18_20605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9C18_20615	COG0135	phosphoribosylanthranilate isomerase activity
D9C18_20620	COG0133	tryptophan synthase activity
D9C18_20635	COG0287	Prephenate dehydrogenase
D9C18_20640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9C18_20645	COG0457	Tetratricopeptide repeat
D9C18_20650	COG5582	Belongs to the UPF0302 family
D9C18_20660	COG0723	plastoquinol--plastocyanin reductase activity
D9C18_20665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C18_20670	COG2010	Cytochrome c
D9C18_20670	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C18_20675	COG4347	Protein of unknown function (DUF1405)
D9C18_20685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C18_20690	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C18_20695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9C18_20700	COG1803	Methylglyoxal synthase
D9C18_20705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C18_20710	COG0438	transferase activity, transferring glycosyl groups
D9C18_20715	COG0617	tRNA 3'-terminal CCA addition
D9C18_20720	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D9C18_20720	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D9C18_20725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9C18_20730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9C18_20735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9C18_20740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9C18_20740	COG1199	ATP-dependent helicase activity
D9C18_20750	COG5353	protein conserved in bacteria
D9C18_20755	COG0436	Aminotransferase
D9C18_20760	COG0017	Asparaginyl-tRNA synthetase
D9C18_20765	COG3935	DnaD domain protein
D9C18_20770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9C18_20780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C18_20780	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C18_20785	COG3331	DNA recombination
D9C18_20820	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C18_20825	COG2190	(PTS) system
D9C18_20830	COG1111	helicase
D9C18_20830	COG1205	dead DEAH box helicase
D9C18_20835	COG3359	exonuclease
D9C18_20850	COG4474	Belongs to the UPF0398 family
D9C18_20865	COG0116	Belongs to the methyltransferase superfamily
D9C18_20880	COG1199	ATP-dependent helicase activity
D9C18_20885	COG1028	Short-chain dehydrogenase reductase Sdr
D9C18_20890	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9C18_20895	COG1609	Transcriptional regulator
D9C18_20900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C18_20905	COG0800	Aldolase
D9C18_20915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9C18_20920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C18_20925	COG2233	PERMEase
D9C18_20930	COG3424	synthase
D9C18_20935	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9C18_20945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C18_20960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C18_20970	COG0328	RNA-DNA hybrid ribonuclease activity
D9C18_20975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9C18_20980	COG0328	RNA-DNA hybrid ribonuclease activity
D9C18_21000	COG1278	Cold shock
D9C18_21010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C18_21015	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9C18_21020	COG0386	Belongs to the glutathione peroxidase family
D9C18_21025	COG1418	mRNA catabolic process
D9C18_21030	COG1413	lyase activity
D9C18_21035	COG0129	dihydroxy-acid dehydratase activity
D9C18_21045	COG2136	Putative SAM-dependent methyltransferase
D9C18_21045	COG2521	methyltransferase
D9C18_21055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C18_21060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C18_21065	COG0204	Acyl-transferase
D9C18_21070	COG1272	protein, Hemolysin III
D9C18_21075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C18_21080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9C18_21090	COG1999	signal sequence binding
D9C18_21095	COG2755	lipolytic protein G-D-S-L family
D9C18_21100	COG4698	Protein conserved in bacteria
D9C18_21115	COG1846	Transcriptional regulator
D9C18_21120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C18_21125	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C18_21130	COG1086	Polysaccharide biosynthesis protein
D9C18_21135	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D9C18_21140	COG4641	Protein conserved in bacteria
D9C18_21155	COG0463	Glycosyl transferase, family 2
D9C18_21160	COG0456	acetyltransferase
D9C18_21175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C18_21180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C18_21185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C18_21190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C18_21195	COG0456	acetyltransferase
D9C18_21200	COG1509	lysine 2,3-aminomutase activity
D9C18_21210	COG4479	Belongs to the UPF0346 family
D9C18_21235	COG0671	phosphoesterase, PA-phosphatase related
D9C18_21250	COG0813	purine-nucleoside phosphorylase activity
D9C18_21255	COG1876	peptidase activity
D9C18_21265	COG2226	methyltransferase
D9C18_21270	COG0793	Belongs to the peptidase S41A family
D9C18_21270	COG3409	Peptidoglycan-binding domain 1 protein
D9C18_21275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C18_21290	COG0400	carboxylic ester hydrolase activity
D9C18_21300	COG0778	Nitroreductase
D9C18_21305	COG1733	regulation of RNA biosynthetic process
D9C18_21310	COG1942	4-Oxalocrotonate Tautomerase
D9C18_21330	COG2962	Rard protein
D9C18_21340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C18_21345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C18_21350	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C18_21355	COG0534	Mate efflux family protein
D9C18_21360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C18_21365	COG1819	glycosyl
D9C18_21370	COG1388	LysM domain
D9C18_21370	COG0791	NLP P60 protein
D9C18_21375	COG2032	superoxide dismutase activity
D9C18_21380	COG0714	Associated with various cellular activities
D9C18_21385	COG4548	von Willebrand factor, type A
D9C18_21390	COG0567	Dehydrogenase, E1 component
D9C18_21395	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C18_21400	COG0385	Bile acid
D9C18_21405	COG0733	neurotransmitter:sodium symporter activity
D9C18_21410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C18_21415	COG1657	PFAM Prenyltransferase squalene oxidase
D9C18_21420	COG1012	belongs to the aldehyde dehydrogenase family
D9C18_21445	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C18_21460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C18_21465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C18_21480	COG0514	ATP-dependent DNA helicase (RecQ)
D9C18_21485	COG3584	3D domain protein
D9C18_21485	COG1388	LysM domain
D9C18_21490	COG2197	response regulator
D9C18_21495	COG4585	Histidine kinase
D9C18_21500	COG3239	Fatty acid desaturase
D9C18_21505	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C18_21520	COG2322	membrane
D9C18_21525	COG0741	lytic transglycosylase activity
D9C18_21530	COG0640	Transcriptional regulator
D9C18_21540	COG2378	regulation of single-species biofilm formation
D9C18_21545	COG3708	Transcriptional regulator
D9C18_21550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C18_21555	COG1309	transcriptional regulator
D9C18_21560	COG0456	acetyltransferase
D9C18_21565	COG0662	Cupin 2, conserved barrel domain protein
D9C18_21565	COG2207	Transcriptional regulator
D9C18_21570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C18_21575	COG1231	oxidoreductase activity
D9C18_21580	COG4282	regulation of fungal-type cell wall biogenesis
D9C18_21585	COG5444	nuclease activity
D9C18_21605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_21635	COG3328	transposase activity
D9C18_21640	COG2211	Major facilitator Superfamily
D9C18_21645	COG2226	methyltransferase
D9C18_21650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C18_21710	COG3328	transposase activity
D9C18_21750	COG3328	transposase activity
D9C18_21760	COG2814	Major facilitator Superfamily
D9C18_21770	COG1131	(ABC) transporter
D9C18_21785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C18_21795	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C18_21800	COG0300	oxidoreductase activity
D9C18_21830	COG0583	DNA-binding transcription factor activity
D9C18_21835	COG0070	glutamate synthase
D9C18_21835	COG0069	glutamate synthase activity
D9C18_21835	COG0067	glutamate synthase
D9C18_21840	COG0493	'glutamate synthase
D9C18_21845	COG0604	alcohol dehydrogenase
D9C18_21850	COG0583	DNA-binding transcription factor activity
D9C18_21855	COG0405	Gamma-glutamyltransferase
D9C18_21860	COG0166	Belongs to the GPI family
D9C18_21865	COG0582	viral genome integration into host DNA
D9C18_21885	COG0534	Mate efflux family protein
D9C18_21890	COG2017	converts alpha-aldose to the beta-anomer
D9C18_21895	COG2027	D-alanyl-D-alanine carboxypeptidase
D9C18_21900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C18_21915	COG1649	PFAM Uncharacterised BCR, COG1649
D9C18_21925	COG1960	acyl-CoA dehydrogenase activity
D9C18_21930	COG0318	PFAM AMP-dependent synthetase and ligase
D9C18_21935	COG0439	Biotin carboxylase
D9C18_21940	COG0511	ligase activity, forming carbon-carbon bonds
D9C18_21945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C18_21950	COG1024	Enoyl-CoA hydratase
D9C18_21955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C18_21960	COG2404	hydrolase activity, acting on ester bonds
D9C18_21965	COG0586	Pfam SNARE associated Golgi protein
D9C18_21970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C18_21975	COG2246	polysaccharide biosynthetic process
D9C18_21985	COG5520	Belongs to the glycosyl hydrolase 30 family
D9C18_21995	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9C18_22000	COG1115	amino acid carrier protein
D9C18_22010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C18_22015	COG0187	DNA topoisomerase II activity
D9C18_22020	COG1832	CoA-binding protein
D9C18_22025	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9C18_22030	COG4841	protein insertion into membrane
D9C18_22040	COG0824	Thioesterase
D9C18_22060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C18_22065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9C18_22080	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C18_22090	COG4846	Membrane protein involved in cytochrome C biogenesis
D9C18_22095	COG2201	protein-glutamate methylesterase activity
D9C18_22100	COG0785	Cytochrome C biogenesis protein
D9C18_22110	COG3763	UPF0154 protein
D9C18_22120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9C18_22125	COG4224	UPF0291 protein
D9C18_22130	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C18_22135	COG1388	LysM domain
D9C18_22140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9C18_22150	COG0346	lactoylglutathione lyase activity
D9C18_22160	COG4195	phage-related replication protein
D9C18_22220	COG0629	single-stranded DNA binding
D9C18_22235	COG0582	viral genome integration into host DNA
D9C18_22265	COG1793	dna ligase
D9C18_22280	COG1525	nuclease
D9C18_22390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C18_22440	COG0457	Tetratricopeptide repeat
D9C18_22575	COG3883	PFAM NLP P60 protein
D9C18_22575	COG0791	NLP P60 protein