locus-tag	class	description
BEP06_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BEP06_00010	COG0592	DNA-directed DNA polymerase activity
BEP06_00015	COG2501	S4 domain
BEP06_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BEP06_00030	COG0187	DNA topoisomerase II activity
BEP06_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BEP06_00070	COG0517	IMP dehydrogenase activity
BEP06_00070	COG0516	GMP reductase activity
BEP06_00075	COG1686	Belongs to the peptidase S11 family
BEP06_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BEP06_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BEP06_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BEP06_00100	COG1428	Deoxynucleoside kinase
BEP06_00105	COG1428	Deoxynucleoside kinase
BEP06_00110	COG3858	chitin binding
BEP06_00110	COG1388	LysM domain
BEP06_00115	COG1335	isochorismatase
BEP06_00120	COG0590	tRNA wobble adenosine to inosine editing
BEP06_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BEP06_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BEP06_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BEP06_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BEP06_00190	COG3853	Toxic anion resistance protein (TelA)
BEP06_00195	COG1982	Orn Lys Arg decarboxylase major
BEP06_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BEP06_00205	COG3870	Protein conserved in bacteria
BEP06_00210	COG1728	Protein conserved in bacteria
BEP06_00215	COG0470	DNA polymerase III
BEP06_00220	COG1774	PSP1 C-terminal conserved region
BEP06_00225	COG4467	Involved in initiation control of chromosome replication
BEP06_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BEP06_00235	COG2827	Endonuclease containing a URI domain
BEP06_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BEP06_00245	COG2002	toxin-antitoxin pair type II binding
BEP06_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEP06_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEP06_00255	COG0084	hydrolase, TatD family'
BEP06_00260	COG3583	domain protein
BEP06_00260	COG3584	3D domain protein
BEP06_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BEP06_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BEP06_00280	COG4466	Protein conserved in bacteria
BEP06_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BEP06_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEP06_00300	COG0251	oxidation-reduction process
BEP06_00305	COG2088	sporulation resulting in formation of a cellular spore
BEP06_00315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BEP06_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BEP06_00325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BEP06_00330	COG0193	aminoacyl-tRNA hydrolase activity
BEP06_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BEP06_00345	COG2002	toxin-antitoxin pair type II binding
BEP06_00350	COG2244	polysaccharide biosynthetic process
BEP06_00355	COG3956	TIGRFAM MazG family protein
BEP06_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BEP06_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BEP06_00380	COG1098	S1 RNA binding domain
BEP06_00395	COG2208	phosphoserine phosphatase activity
BEP06_00400	COG2304	oxidoreductase activity
BEP06_00405	COG0515	serine threonine protein kinase
BEP06_00410	COG0037	tRNA processing
BEP06_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BEP06_00425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BEP06_00430	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BEP06_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEP06_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BEP06_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BEP06_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
BEP06_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BEP06_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BEP06_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BEP06_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BEP06_00475	COG1396	sequence-specific DNA binding
BEP06_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BEP06_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BEP06_00570	COG4463	regulation of RNA biosynthetic process
BEP06_00575	COG3880	PFAM UvrB UvrC protein
BEP06_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BEP06_00585	COG0542	response to heat
BEP06_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BEP06_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BEP06_00600	COG4956	integral membrane protein (PIN domain superfamily)
BEP06_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BEP06_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BEP06_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEP06_00625	COG1045	serine acetyltransferase
BEP06_00630	COG0215	cysteine-tRNA ligase activity
BEP06_00635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BEP06_00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEP06_00645	COG3688	RNA-binding protein containing a PIN domain
BEP06_00650	COG1595	DNA-templated transcription, initiation
BEP06_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BEP06_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BEP06_00665	COG0250	Participates in transcription elongation, termination and antitermination
BEP06_00670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BEP06_00675	COG0081	regulation of translation
BEP06_00680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BEP06_00685	COG0222	ribosome binding
BEP06_00690	COG2813	Specifically methylates the guanine in position
BEP06_00695	COG0085	RNA polymerase activity
BEP06_00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BEP06_00705	COG1358	cellular component organization or biogenesis
BEP06_00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BEP06_00715	COG0049	tRNA binding
BEP06_00720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BEP06_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BEP06_00730	COG0596	Alpha beta hydrolase
BEP06_00735	COG0051	transcription antitermination factor activity, RNA binding
BEP06_00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BEP06_00745	COG0088	Forms part of the polypeptide exit tunnel
BEP06_00750	COG0089	rRNA binding
BEP06_00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BEP06_00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BEP06_00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BEP06_00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BEP06_00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BEP06_00780	COG0255	Belongs to the universal ribosomal protein uL29 family
BEP06_00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BEP06_00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BEP06_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BEP06_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BEP06_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BEP06_00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BEP06_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BEP06_00830	COG1841	ribosomal large subunit assembly
BEP06_00835	COG0200	Binds to the 23S rRNA
BEP06_00840	COG0201	protein transport
BEP06_00845	COG0563	adenylate kinase activity
BEP06_00850	COG0024	Methionine aminopeptidase
BEP06_00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BEP06_00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BEP06_00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BEP06_00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BEP06_00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BEP06_00880	COG0202	RNA polymerase activity
BEP06_00885	COG0203	ribosomal protein L17
BEP06_00890	COG1122	ATPase activity
BEP06_00895	COG1122	ATPase activity
BEP06_00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BEP06_00905	COG0101	tRNA pseudouridine synthase activity
BEP06_00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BEP06_00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BEP06_00920	COG2226	methyltransferase
BEP06_00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
BEP06_00935	COG0489	protein tyrosine kinase activity
BEP06_00945	COG2194	sulfuric ester hydrolase activity
BEP06_00950	COG0726	polysaccharide deacetylase
BEP06_01035	COG0659	secondary active sulfate transmembrane transporter activity
BEP06_01040	COG0385	Bile acid
BEP06_01045	COG2819	hydrolase of the alpha beta superfamily
BEP06_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_01055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEP06_01065	COG2207	Transcriptional regulator
BEP06_01065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEP06_01070	COG3876	Protein conserved in bacteria
BEP06_01075	COG1472	Belongs to the glycosyl hydrolase 3 family
BEP06_01080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BEP06_01085	COG1263	PTS System
BEP06_01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_01090	COG1737	Transcriptional regulator
BEP06_01095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BEP06_01100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BEP06_01105	COG1683	Conserved Protein
BEP06_01135	COG1595	DNA-templated transcription, initiation
BEP06_01140	COG5662	AntiSigma factor
BEP06_01145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BEP06_01150	COG4856	YbbR-like protein
BEP06_01155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEP06_01160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BEP06_01165	COG0584	glycerophosphoryl diester phosphodiesterase
BEP06_01170	COG2271	Major facilitator Superfamily
BEP06_01180	COG0456	acetyltransferase
BEP06_01180	COG1846	Transcriptional regulator
BEP06_01185	COG2271	Major facilitator Superfamily
BEP06_01200	COG3409	Peptidoglycan-binding domain 1 protein
BEP06_01205	COG0697	spore germination
BEP06_01210	COG2207	Transcriptional regulator
BEP06_01210	COG1917	Cupin 2, conserved barrel domain protein
BEP06_01215	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BEP06_01220	COG0596	Alpha beta hydrolase
BEP06_01225	COG1183	phosphatidylcholine synthase activity
BEP06_01230	COG0586	Pfam SNARE associated Golgi protein
BEP06_01235	COG0688	phosphatidylethanolamine metabolic process
BEP06_01245	COG2312	Erythromycin esterase
BEP06_01250	COG2207	Transcriptional regulator
BEP06_01260	COG1301	dicarboxylic acid transport
BEP06_01265	COG1263	PTS System
BEP06_01265	COG2190	(PTS) system
BEP06_01265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_01270	COG0363	glucosamine-6-phosphate deaminase activity
BEP06_01285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BEP06_01290	COG0833	amino acid
BEP06_01295	COG2040	homocysteine
BEP06_01305	COG1115	amino acid carrier protein
BEP06_01310	COG2066	Belongs to the glutaminase family
BEP06_01315	COG4191	Histidine kinase
BEP06_01320	COG0784	Response regulator, receiver
BEP06_01330	COG0697	spore germination
BEP06_01335	COG0745	RESPONSE REGULATOR receiver
BEP06_01340	COG2205	protein histidine kinase activity
BEP06_01345	COG1131	(ABC) transporter
BEP06_01365	COG3773	Cell wall hydrolase
BEP06_01370	COG2304	oxidoreductase activity
BEP06_01380	COG3540	Alkaline phosphatase
BEP06_01385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BEP06_01390	COG0805	protein transport
BEP06_01395	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BEP06_01400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BEP06_01405	COG0477	Major facilitator Superfamily
BEP06_01410	COG1309	transcriptional regulator
BEP06_01415	COG0252	asparaginase activity
BEP06_01420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BEP06_01425	COG1714	RDD family
BEP06_01430	COG1405	negative regulation of cell septum assembly
BEP06_01430	COG3012	SEC-C Motif Domain Protein
BEP06_01435	COG3290	protein histidine kinase activity
BEP06_01440	COG3279	Response regulator of the LytR AlgR family
BEP06_01445	COG4555	ABC transporter
BEP06_01450	COG1668	transmembrane transport
BEP06_01455	COG0667	Aldo Keto reductase
BEP06_01465	COG1595	DNA-templated transcription, initiation
BEP06_01470	COG1595	DNA-templated transcription, initiation
BEP06_01475	COG1876	peptidase activity
BEP06_01480	COG0457	Tetratricopeptide repeat
BEP06_01485	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_01490	COG0366	Alpha amylase catalytic
BEP06_01495	COG0803	Belongs to the bacterial solute-binding protein 9 family
BEP06_01500	COG1121	(ABC) transporter
BEP06_01505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BEP06_01510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEP06_01515	COG2310	stress, protein
BEP06_01520	COG2310	stress, protein
BEP06_01525	COG2310	stress, protein
BEP06_01530	COG0861	Integral membrane protein TerC family
BEP06_01540	COG3853	Toxic anion resistance protein (TelA)
BEP06_01545	COG0477	Major facilitator Superfamily
BEP06_01550	COG2814	Major facilitator Superfamily
BEP06_01555	COG0640	Transcriptional regulator
BEP06_01560	COG4175	Glycine betaine
BEP06_01560	COG0517	IMP dehydrogenase activity
BEP06_01565	COG4176	ABC-type proline glycine betaine transport system permease component
BEP06_01570	COG2113	Glycine betaine
BEP06_01575	COG1473	amidohydrolase
BEP06_01580	COG1288	antiporter activity
BEP06_01595	COG0366	Alpha amylase catalytic
BEP06_01600	COG0039	L-malate dehydrogenase activity
BEP06_01605	COG1620	l-lactate permease
BEP06_01610	COG2814	Major facilitator Superfamily
BEP06_01615	COG1846	Transcriptional regulator
BEP06_01620	COG1280	lysine exporter protein (LysE YggA)
BEP06_01625	COG3403	YqcI/YcgG family
BEP06_01630	COG1113	amino acid transport
BEP06_01635	COG3665	Urea carboxylase-associated protein
BEP06_01640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BEP06_01645	COG1660	Displays ATPase and GTPase activities
BEP06_01650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BEP06_01655	COG2226	methyltransferase
BEP06_01660	COG0583	DNA-binding transcription factor activity
BEP06_01665	COG3458	cephalosporin-C deacetylase activity
BEP06_01670	COG3541	Predicted nucleotidyltransferase
BEP06_01675	COG0506	proline dehydrogenase activity
BEP06_01680	COG1012	belongs to the aldehyde dehydrogenase family
BEP06_01685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEP06_01690	COG2508	Transcriptional regulator
BEP06_01695	COG3689	TIGRFAM TIGR03943 family protein
BEP06_01700	COG0701	Predicted permease
BEP06_01705	COG2267	carboxylic ester hydrolase activity
BEP06_01710	COG0492	ferredoxin-NADP+ reductase activity
BEP06_01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BEP06_01715	COG1587	Uroporphyrinogen-III synthase
BEP06_01720	COG2146	nitrite reductase [NAD(P)H] activity
BEP06_01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEP06_01730	COG0243	molybdopterin cofactor binding
BEP06_01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEP06_01740	COG2223	nitrite transmembrane transporter activity
BEP06_01745	COG1469	GTP cyclohydrolase I activity
BEP06_01750	COG1376	ErfK ybiS ycfS ynhG family protein
BEP06_01760	COG0523	cobalamin synthesis protein
BEP06_01765	COG0765	amino acid transport
BEP06_01770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BEP06_01780	COG1714	RDD family
BEP06_01790	COG2723	6-phospho-beta-galactosidase activity
BEP06_01800	COG3209	COG3209 Rhs family protein
BEP06_01805	COG3290	protein histidine kinase activity
BEP06_01805	COG0840	transmembrane signaling receptor activity
BEP06_01810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BEP06_01815	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BEP06_01820	COG1733	regulation of RNA biosynthetic process
BEP06_01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEP06_01835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEP06_01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEP06_01845	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BEP06_01850	COG2814	Major facilitator Superfamily
BEP06_01860	COG0697	spore germination
BEP06_01865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEP06_01875	COG2364	Membrane
BEP06_01880	COG1126	abc transporter atp-binding protein
BEP06_01885	COG0765	amino acid transport
BEP06_01890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BEP06_01895	COG0583	DNA-binding transcription factor activity
BEP06_01900	COG0163	prenyltransferase activity
BEP06_01905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BEP06_01920	COG0596	Alpha beta hydrolase
BEP06_01925	COG3104	oligopeptide transport
BEP06_01930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEP06_01935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BEP06_01940	COG1012	belongs to the aldehyde dehydrogenase family
BEP06_01945	COG4975	Glucose uptake
BEP06_01950	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_01955	COG4549	nuclear export factor GLE1
BEP06_01960	COG1276	copper resistance
BEP06_01960	COG2372	response to copper ion
BEP06_01965	COG1349	DNA-binding transcription factor activity
BEP06_01975	COG2213	PTS system mannitol-specific
BEP06_01980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEP06_01985	COG0246	Mannitol dehydrogenase
BEP06_01990	COG0473	3-isopropylmalate dehydrogenase activity
BEP06_01995	COG0681	Belongs to the peptidase S26 family
BEP06_02005	COG0412	Dienelactone hydrolase
BEP06_02010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BEP06_02020	COG0561	phosphatase activity
BEP06_02025	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BEP06_02030	COG1914	H( )-stimulated, divalent metal cation uptake system
BEP06_02035	COG4336	lyase activity
BEP06_02040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BEP06_02045	COG1984	allophanate hydrolase subunit 2
BEP06_02050	COG1414	Transcriptional regulator
BEP06_02055	COG2755	lipolytic protein G-D-S-L family
BEP06_02065	COG2329	Antibiotic biosynthesis monooxygenase
BEP06_02070	COG0768	penicillin binding
BEP06_02075	COG4989	oxidoreductase activity
BEP06_02080	COG3711	transcriptional antiterminator
BEP06_02085	COG0318	PFAM AMP-dependent synthetase and ligase
BEP06_02090	COG2226	methyltransferase
BEP06_02095	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_02100	COG1917	Cupin 2, conserved barrel domain protein
BEP06_02105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BEP06_02110	COG3871	stress protein (general stress protein 26)
BEP06_02120	COG2814	Major facilitator Superfamily
BEP06_02125	COG1522	sequence-specific DNA binding
BEP06_02130	COG0551	DNA topoisomerase type I activity
BEP06_02130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BEP06_02135	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BEP06_02140	COG3706	GGDEF domain
BEP06_02145	COG5298	Protein conserved in bacteria
BEP06_02150	COG1215	transferase activity, transferring glycosyl groups
BEP06_02160	COG0531	amino acid
BEP06_02165	COG0494	nUDIX hydrolase
BEP06_02170	COG0028	Belongs to the TPP enzyme family
BEP06_02185	COG1914	H( )-stimulated, divalent metal cation uptake system
BEP06_02190	COG2261	transglycosylase associated protein
BEP06_02195	COG4876	unkown
BEP06_02200	COG2217	Heavy metal translocating P-type atpase
BEP06_02205	COG3729	General stress protein
BEP06_02210	COG0662	Cupin 2, conserved barrel domain protein
BEP06_02215	COG2329	Antibiotic biosynthesis monooxygenase
BEP06_02220	COG3546	catalase activity
BEP06_02225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BEP06_02230	COG3290	protein histidine kinase activity
BEP06_02235	COG4565	transcriptional regulatory protein
BEP06_02240	COG1301	dicarboxylic acid transport
BEP06_02245	COG0628	permease
BEP06_02255	COG1131	(ABC) transporter
BEP06_02260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BEP06_02270	COG1960	acyl-CoA dehydrogenase activity
BEP06_02285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BEP06_02290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_02295	COG1181	Belongs to the D-alanine--D-alanine ligase family
BEP06_02300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BEP06_02305	COG0513	Belongs to the DEAD box helicase family
BEP06_02310	COG3402	PFAM membrane-flanked domain
BEP06_02315	COG3428	Bacterial PH domain
BEP06_02320	COG0705	Rhomboid family
BEP06_02325	COG0736	holo-[acyl-carrier-protein] synthase activity
BEP06_02330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BEP06_02335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BEP06_02340	COG0864	Transcriptional regulator
BEP06_02345	COG2337	Toxic component of a toxin-antitoxin (TA) module
BEP06_02350	COG1366	Belongs to the anti-sigma-factor antagonist family
BEP06_02355	COG1366	Belongs to the anti-sigma-factor antagonist family
BEP06_02360	COG2172	sigma factor antagonist activity
BEP06_02365	COG2208	phosphoserine phosphatase activity
BEP06_02370	COG1366	Belongs to the anti-sigma-factor antagonist family
BEP06_02375	COG2172	sigma factor antagonist activity
BEP06_02380	COG1191	sigma factor activity
BEP06_02385	COG2208	phosphoserine phosphatase activity
BEP06_02400	COG1673	EVE domain
BEP06_02405	COG1846	Transcriptional regulator
BEP06_02410	COG2183	response to ionizing radiation
BEP06_02420	COG3091	SprT-like family
BEP06_02460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEP06_02465	COG1522	sequence-specific DNA binding
BEP06_02470	COG1522	sequence-specific DNA binding
BEP06_02475	COG1335	isochorismatase
BEP06_02480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BEP06_02485	COG2814	Major facilitator Superfamily
BEP06_02505	COG0693	protein deglycase activity
BEP06_02510	COG1278	Cold shock
BEP06_02515	COG1329	Transcriptional regulator
BEP06_02520	COG0697	spore germination
BEP06_02525	COG1917	Cupin 2, conserved barrel domain protein
BEP06_02525	COG2207	Transcriptional regulator
BEP06_02530	COG0697	spore germination
BEP06_02535	COG2207	Transcriptional regulator
BEP06_02535	COG3708	Transcriptional regulator
BEP06_02540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEP06_02545	COG0477	Major facilitator Superfamily
BEP06_02555	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BEP06_02565	COG0697	spore germination
BEP06_02570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEP06_02575	COG2030	dehydratase
BEP06_02580	COG3545	Serine hydrolase
BEP06_02585	COG1733	regulation of RNA biosynthetic process
BEP06_02590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BEP06_02595	COG1733	regulation of RNA biosynthetic process
BEP06_02600	COG2249	NAD(P)H dehydrogenase (quinone) activity
BEP06_02605	COG2814	Major facilitator Superfamily
BEP06_02610	COG1309	transcriptional regulator
BEP06_02620	COG0640	Transcriptional regulator
BEP06_02625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BEP06_02635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BEP06_02640	COG0697	spore germination
BEP06_02645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEP06_02650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEP06_02655	COG0640	Transcriptional regulator
BEP06_02660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BEP06_02670	COG4585	Histidine kinase
BEP06_02675	COG2197	response regulator
BEP06_02680	COG2409	Drug exporters of the RND superfamily
BEP06_02685	COG0596	Alpha beta hydrolase
BEP06_02690	COG1811	Na channel or pump
BEP06_02695	COG4978	Transcriptional regulator
BEP06_02695	COG0789	Transcriptional regulator
BEP06_02700	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BEP06_02705	COG0778	Nitroreductase
BEP06_02710	COG0346	lactoylglutathione lyase activity
BEP06_02715	COG2259	Doxx family
BEP06_02720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_02740	COG2323	membrane
BEP06_02745	COG2323	membrane
BEP06_02750	COG0071	Belongs to the small heat shock protein (HSP20) family
BEP06_02765	COG1309	transcriptional regulator
BEP06_02775	COG0456	acetyltransferase
BEP06_02785	COG1113	amino acid transport
BEP06_02790	COG2318	DinB family
BEP06_02835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BEP06_02840	COG0802	atpase or kinase
BEP06_02845	COG1214	PFAM Peptidase M22, glycoprotease
BEP06_02850	COG0456	acetyltransferase
BEP06_02855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BEP06_02860	COG0488	(ABC) transporter
BEP06_02865	COG0315	cyclic pyranopterin monophosphate synthase activity
BEP06_02870	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BEP06_02875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BEP06_02880	COG0805	protein transport
BEP06_02890	COG1266	CAAX protease self-immunity
BEP06_02895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BEP06_02900	COG0459	protein refolding
BEP06_02915	COG0457	Tetratricopeptide repeat
BEP06_02920	COG1063	alcohol dehydrogenase
BEP06_02925	COG2211	Major facilitator Superfamily
BEP06_02930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BEP06_02935	COG1305	Transglutaminase-like
BEP06_02940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BEP06_02940	COG0519	Catalyzes the synthesis of GMP from XMP
BEP06_02945	COG2252	PERMEase
BEP06_02950	COG3064	Membrane
BEP06_02960	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BEP06_02970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BEP06_02975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BEP06_02980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BEP06_02985	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BEP06_02990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BEP06_02995	COG0047	phosphoribosylformylglycinamidine synthase activity
BEP06_03000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BEP06_03005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BEP06_03010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BEP06_03015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BEP06_03020	COG0138	bifunctional purine biosynthesis protein purh
BEP06_03025	COG0151	Belongs to the GarS family
BEP06_03030	COG1522	sequence-specific DNA binding
BEP06_03035	COG0531	amino acid
BEP06_03045	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BEP06_03050	COG1470	cell adhesion involved in biofilm formation
BEP06_03055	COG4496	protein, YerC YecD
BEP06_03060	COG0069	glutamate synthase activity
BEP06_03070	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BEP06_03075	COG0210	DNA helicase
BEP06_03080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BEP06_03085	COG4851	CamS sex pheromone cAM373 precursor
BEP06_03090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BEP06_03095	COG1285	pathogenesis
BEP06_03100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEP06_03105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEP06_03110	COG0154	amidase activity
BEP06_03115	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEP06_03120	COG1309	transcriptional regulator
BEP06_03125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BEP06_03130	COG1597	lipid kinase activity
BEP06_03135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BEP06_03140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BEP06_03140	COG2124	cytochrome p450
BEP06_03145	COG1368	sulfuric ester hydrolase activity
BEP06_03150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BEP06_03155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BEP06_03160	COG1442	glycosyl transferase family 8
BEP06_03165	COG1216	Glycosyl transferase, family 2
BEP06_03170	COG1442	glycosyl transferase family 8
BEP06_03175	COG2223	nitrite transmembrane transporter activity
BEP06_03180	COG1011	Hydrolase
BEP06_03185	COG0531	amino acid
BEP06_03190	COG1012	belongs to the aldehyde dehydrogenase family
BEP06_03195	COG0840	transmembrane signaling receptor activity
BEP06_03200	COG0488	(ABC) transporter
BEP06_03210	COG0789	Transcriptional regulator
BEP06_03215	COG2814	Major facilitator Superfamily
BEP06_03230	COG0488	(ABC) transporter
BEP06_03235	COG0513	Belongs to the DEAD box helicase family
BEP06_03240	COG0456	acetyltransferase
BEP06_03245	COG2130	NADP-dependent
BEP06_03260	COG2211	Major facilitator Superfamily
BEP06_03265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BEP06_03270	COG1120	ATPase activity
BEP06_03275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_03280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_03285	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BEP06_03300	COG3866	Pectate lyase
BEP06_03305	COG0471	metal ion transport
BEP06_03310	COG3290	protein histidine kinase activity
BEP06_03315	COG4565	transcriptional regulatory protein
BEP06_03320	COG3181	Tripartite tricarboxylate transporter family receptor
BEP06_03330	COG2851	Citrate transporter
BEP06_03335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEP06_03340	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BEP06_03345	COG1254	Belongs to the acylphosphatase family
BEP06_03350	COG2258	MOSC domain
BEP06_03370	COG0024	Methionine aminopeptidase
BEP06_03375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_03375	COG1263	PTS System
BEP06_03380	COG1368	sulfuric ester hydrolase activity
BEP06_03390	COG1115	amino acid carrier protein
BEP06_03395	COG0531	amino acid
BEP06_03410	COG0697	spore germination
BEP06_03415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_03415	COG1263	PTS System
BEP06_03420	COG0366	Alpha amylase catalytic
BEP06_03425	COG2188	Transcriptional regulator
BEP06_03430	COG0778	Nitroreductase
BEP06_03435	COG0737	Belongs to the 5'-nucleotidase family
BEP06_03440	COG0693	protein deglycase activity
BEP06_03445	COG2814	Major facilitator Superfamily
BEP06_03450	COG4840	Belongs to the UPF0435 family
BEP06_03455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEP06_03460	COG4980	gas vesicle protein
BEP06_03465	COG1295	ribonuclease BN
BEP06_03475	COG0477	Major facilitator Superfamily
BEP06_03485	COG0387	Pfam Sodium calcium exchanger
BEP06_03495	COG0668	transmembrane transport
BEP06_03500	COG0535	radical SAM domain protein
BEP06_03510	COG0726	polysaccharide deacetylase
BEP06_03515	COG2084	Dehydrogenase
BEP06_03520	COG0598	Magnesium transport protein CorA
BEP06_03525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BEP06_03530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BEP06_03540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BEP06_03545	COG4637	Psort location Cytoplasmic, score
BEP06_03555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BEP06_03560	COG0022	dehydrogenase e1 component
BEP06_03565	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEP06_03570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEP06_03575	COG3284	Transcriptional regulator
BEP06_03580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BEP06_03580	COG0392	lysyltransferase activity
BEP06_03585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEP06_03590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_03595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_03600	COG0384	phenazine biosynthesis protein PhzF
BEP06_03605	COG0778	Nitroreductase
BEP06_03620	COG1090	epimerase
BEP06_03625	COG2137	regulation of response to DNA damage stimulus
BEP06_03630	COG1194	a g-specific adenine glycosylase
BEP06_03640	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_03655	COG3557	Belongs to the UPF0374 family
BEP06_03660	COG1132	(ABC) transporter
BEP06_03665	COG4129	membrane
BEP06_03670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BEP06_03675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BEP06_03680	COG0735	belongs to the Fur family
BEP06_03795	COG4326	sporulation control protein
BEP06_03805	COG5577	PFAM Coat F domain
BEP06_03810	COG3340	Belongs to the peptidase S51 family
BEP06_03815	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BEP06_03820	COG0277	FAD linked oxidase domain protein
BEP06_03830	COG0753	catalase activity
BEP06_03835	COG1116	anion transmembrane transporter activity
BEP06_03840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BEP06_03845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BEP06_03850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEP06_03860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BEP06_03870	COG1476	TRANSCRIPTIONal
BEP06_03880	COG3382	B3 4 domain protein
BEP06_03885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BEP06_03895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BEP06_03900	COG0789	Transcriptional regulator
BEP06_03905	COG1664	Polymer-forming cytoskeletal
BEP06_03910	COG1664	Polymer-forming cytoskeletal
BEP06_03915	COG2766	serine protein kinase
BEP06_03920	COG2718	Belongs to the UPF0229 family
BEP06_03930	COG1846	Transcriptional regulator
BEP06_03935	COG1566	PFAM secretion protein HlyD family protein
BEP06_03940	COG2814	Major facilitator Superfamily
BEP06_03945	COG0655	NAD(P)H dehydrogenase (quinone) activity
BEP06_03960	COG1725	Transcriptional regulator
BEP06_03965	COG1131	(ABC) transporter
BEP06_03970	COG1131	(ABC) transporter
BEP06_03975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BEP06_03980	COG1278	Cold shock
BEP06_03985	COG1464	Belongs to the NlpA lipoprotein family
BEP06_03990	COG3706	GGDEF domain
BEP06_03995	COG1823	symporter activity
BEP06_04015	COG5577	PFAM Coat F domain
BEP06_04020	COG4085	toxin activity
BEP06_04020	COG0737	Belongs to the 5'-nucleotidase family
BEP06_04020	COG1525	nuclease
BEP06_04025	COG3764	Sortase (surface protein transpeptidase)
BEP06_04030	COG0564	pseudouridine synthase activity
BEP06_04040	COG0517	IMP dehydrogenase activity
BEP06_04045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BEP06_04050	COG3153	acetyltransferase
BEP06_04050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BEP06_04055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BEP06_04060	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BEP06_04065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BEP06_04070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BEP06_04075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BEP06_04080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEP06_04085	COG4585	Histidine kinase
BEP06_04085	COG2203	Gaf domain
BEP06_04090	COG2197	response regulator
BEP06_04095	COG0431	NADPH-dependent FMN reductase
BEP06_04110	COG0791	NLP P60 protein
BEP06_04110	COG1388	LysM domain
BEP06_04115	COG1959	2 iron, 2 sulfur cluster binding
BEP06_04120	COG0668	transmembrane transport
BEP06_04125	COG2719	SpoVR family
BEP06_04130	COG1785	Belongs to the alkaline phosphatase family
BEP06_04135	COG0791	NLP P60 protein
BEP06_04135	COG1388	LysM domain
BEP06_04140	COG0583	DNA-binding transcription factor activity
BEP06_04145	COG0372	Belongs to the citrate synthase family
BEP06_04150	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_04155	COG0531	amino acid
BEP06_04160	COG0733	neurotransmitter:sodium symporter activity
BEP06_04165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BEP06_04170	COG0456	acetyltransferase
BEP06_04185	COG1595	DNA-templated transcription, initiation
BEP06_04190	COG0667	Aldo Keto reductase
BEP06_04195	COG0204	Acyl-transferase
BEP06_04200	COG1253	flavin adenine dinucleotide binding
BEP06_04205	COG0789	Transcriptional regulator
BEP06_04210	COG0436	Aminotransferase
BEP06_04215	COG1253	flavin adenine dinucleotide binding
BEP06_04220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BEP06_04225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BEP06_04230	COG0584	glycerophosphoryl diester phosphodiesterase
BEP06_04240	COG0668	transmembrane transport
BEP06_04245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BEP06_04250	COG0726	polysaccharide deacetylase
BEP06_04255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BEP06_04260	COG1757	Na H antiporter
BEP06_04265	COG0589	response to stress
BEP06_04275	COG1132	(ABC) transporter
BEP06_04280	COG1132	(ABC) transporter
BEP06_04285	COG0702	epimerase
BEP06_04300	COG0189	ligase activity
BEP06_04305	COG0189	ligase activity
BEP06_04310	COG4399	Belongs to the UPF0754 family
BEP06_04315	COG3679	Belongs to the UPF0342 family
BEP06_04320	COG4335	DNA alkylation repair
BEP06_04325	COG0561	phosphatase activity
BEP06_04330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BEP06_04335	COG0475	glutathione-regulated potassium exporter activity
BEP06_04340	COG0490	domain, Protein
BEP06_04350	COG1024	Enoyl-CoA hydratase
BEP06_04360	COG4152	abc transporter atp-binding protein
BEP06_04365	COG1668	transmembrane transport
BEP06_04370	COG0420	3'-5' exonuclease activity
BEP06_04375	COG4717	serine-type aminopeptidase activity
BEP06_04380	COG3481	metal-dependent phosphohydrolase, HD sub domain
BEP06_04390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEP06_04410	COG1846	Transcriptional regulator
BEP06_04415	COG4980	gas vesicle protein
BEP06_04430	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BEP06_04435	COG0537	adenosine 5'-monophosphoramidase activity
BEP06_04440	COG1131	(ABC) transporter
BEP06_04445	COG4473	ABC transporter
BEP06_04455	COG1473	amidohydrolase
BEP06_04460	COG3069	C4-dicarboxylate transmembrane transporter activity
BEP06_04470	COG2329	Antibiotic biosynthesis monooxygenase
BEP06_04475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEP06_04480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BEP06_04495	COG1309	transcriptional regulator
BEP06_04500	COG1511	domain protein
BEP06_04505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BEP06_04510	COG4377	Putative membrane peptidase family (DUF2324)
BEP06_04520	COG1363	Peptidase, m42
BEP06_04525	COG4405	Protein conserved in bacteria
BEP06_04530	COG1301	dicarboxylic acid transport
BEP06_04540	COG1234	tRNA 3'-trailer cleavage
BEP06_04545	COG0095	Lipoate-protein ligase
BEP06_04550	COG0702	epimerase
BEP06_04555	COG0318	PFAM AMP-dependent synthetase and ligase
BEP06_04565	COG0406	alpha-ribazole phosphatase activity
BEP06_04570	COG0183	Belongs to the thiolase family
BEP06_04575	COG0318	PFAM AMP-dependent synthetase and ligase
BEP06_04580	COG1268	BioY protein
BEP06_04585	COG0840	transmembrane signaling receptor activity
BEP06_04590	COG0723	plastoquinol--plastocyanin reductase activity
BEP06_04590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BEP06_04595	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_04605	COG4903	ComK protein
BEP06_04610	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_04620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEP06_04635	COG0398	Pfam SNARE associated Golgi protein
BEP06_04640	COG0681	Belongs to the peptidase S26 family
BEP06_04645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BEP06_04650	COG1846	Transcriptional regulator
BEP06_04655	COG3180	Ammonia monooxygenase
BEP06_04660	COG2814	Major facilitator Superfamily
BEP06_04660	COG0477	Major facilitator Superfamily
BEP06_04665	COG4533	DNA binding
BEP06_04675	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BEP06_04680	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BEP06_04685	COG1074	ATP-dependent DNA helicase activity
BEP06_04690	COG0420	3'-5' exonuclease activity
BEP06_04695	COG0419	ATPase involved in DNA repair
BEP06_04700	COG1403	HNH endonuclease
BEP06_04705	COG1744	ABC transporter substrate-binding protein PnrA-like
BEP06_04720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BEP06_04725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BEP06_04730	COG5504	Zn-dependent protease
BEP06_04735	COG0444	Belongs to the ABC transporter superfamily
BEP06_04740	COG4608	Belongs to the ABC transporter superfamily
BEP06_04750	COG0601	transmembrane transport
BEP06_04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BEP06_04765	COG0180	Tryptophanyl-tRNA synthetase
BEP06_04770	COG4166	transmembrane transport
BEP06_04775	COG0601	transmembrane transport
BEP06_04780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BEP06_04785	COG0444	Belongs to the ABC transporter superfamily
BEP06_04790	COG4608	Belongs to the ABC transporter superfamily
BEP06_04795	COG2814	Major facilitator Superfamily
BEP06_04800	COG0456	acetyltransferase
BEP06_04805	COG1393	Belongs to the ArsC family
BEP06_04810	COG0861	Integral membrane protein TerC family
BEP06_04815	COG4862	establishment of competence for transformation
BEP06_04820	COG4469	Competence protein
BEP06_04825	COG1164	Oligoendopeptidase f
BEP06_04845	COG2346	COG2346, Truncated hemoglobins
BEP06_04850	COG0741	lytic transglycosylase activity
BEP06_04855	COG4116	CYTH
BEP06_04865	COG2357	RelA SpoT domain protein
BEP06_04870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BEP06_04875	COG0564	pseudouridine synthase activity
BEP06_04880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BEP06_04885	COG0475	glutathione-regulated potassium exporter activity
BEP06_04885	COG0569	domain protein
BEP06_04890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BEP06_04895	COG0352	thiamine-phosphate diphosphorylase activity
BEP06_04900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BEP06_04905	COG2104	thiamine diphosphate biosynthetic process
BEP06_04910	COG2022	thiamine diphosphate biosynthetic process
BEP06_04915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BEP06_04920	COG0351	phosphomethylpyrimidine kinase
BEP06_04925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BEP06_04930	COG0210	DNA helicase
BEP06_04940	COG2153	protein acetylation
BEP06_04945	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BEP06_04950	COG2382	esterase
BEP06_04955	COG0626	cystathionine gamma-synthase activity
BEP06_04960	COG0626	cystathionine gamma-synthase activity
BEP06_04965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BEP06_04970	COG5505	Protein of unknown function (DUF819)
BEP06_05005	COG3677	Transposase
BEP06_05020	COG5484	DNA packaging
BEP06_05025	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BEP06_05030	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_05040	COG3711	transcriptional antiterminator
BEP06_05040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEP06_05045	COG0109	protoheme IX farnesyltransferase activity
BEP06_05055	COG1252	NADH dehydrogenase
BEP06_05060	COG0306	phosphate transporter
BEP06_05065	COG1392	Phosphate transport regulator
BEP06_05070	COG0531	amino acid
BEP06_05075	COG0346	lactoylglutathione lyase activity
BEP06_05080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BEP06_05085	COG0463	Glycosyl transferase, family 2
BEP06_05095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEP06_05100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BEP06_05105	COG2362	D-Aminopeptidase
BEP06_05110	COG0601	transmembrane transport
BEP06_05115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BEP06_05120	COG0444	Belongs to the ABC transporter superfamily
BEP06_05125	COG4166	transmembrane transport
BEP06_05130	COG1619	proteins homologs of microcin C7 resistance protein MccF
BEP06_05135	COG4948	Mandelate Racemase Muconate Lactonizing
BEP06_05140	COG0791	NLP P60 protein
BEP06_05145	COG4608	Belongs to the ABC transporter superfamily
BEP06_05150	COG2706	6-phosphogluconolactonase activity
BEP06_05155	COG1834	amidinotransferase
BEP06_05160	COG1607	acyl-coa hydrolase
BEP06_05165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEP06_05165	COG1017	nitric oxide dioxygenase activity
BEP06_05175	COG2323	membrane
BEP06_05180	COG2318	DinB family
BEP06_05185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BEP06_05190	COG2076	Multidrug Resistance protein
BEP06_05195	COG2076	Multidrug Resistance protein
BEP06_05200	COG0788	formyltetrahydrofolate deformylase activity
BEP06_05205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BEP06_05210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BEP06_05215	COG1764	response to oxidative stress
BEP06_05220	COG1846	Transcriptional regulator
BEP06_05225	COG1764	response to oxidative stress
BEP06_05235	COG0590	tRNA wobble adenosine to inosine editing
BEP06_05240	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BEP06_05245	COG1404	Belongs to the peptidase S8 family
BEP06_05250	COG1366	Belongs to the anti-sigma-factor antagonist family
BEP06_05255	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BEP06_05260	COG1122	ATPase activity
BEP06_05265	COG4721	ABC-type cobalt transport system, permease component
BEP06_05275	COG0745	RESPONSE REGULATOR receiver
BEP06_05280	COG3850	Histidine kinase
BEP06_05280	COG5002	protein histidine kinase activity
BEP06_05285	COG3212	peptidase
BEP06_05290	COG3212	peptidase
BEP06_05310	COG2239	Acts as a magnesium transporter
BEP06_05315	COG0789	Transcriptional regulator
BEP06_05320	COG3285	dna ligase
BEP06_05320	COG1793	dna ligase
BEP06_05325	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BEP06_05330	COG3300	MHYT domain
BEP06_05330	COG5001	Diguanylate cyclase
BEP06_05335	COG0586	Pfam SNARE associated Golgi protein
BEP06_05340	COG0861	Integral membrane protein TerC family
BEP06_05345	COG1191	sigma factor activity
BEP06_05365	COG0501	Belongs to the peptidase M48B family
BEP06_05370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BEP06_05385	COG3594	Acyltransferase
BEP06_05390	COG5002	protein histidine kinase activity
BEP06_05395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BEP06_05405	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BEP06_05410	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BEP06_05415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BEP06_05420	COG0436	Aminotransferase
BEP06_05425	COG1850	ribulose-bisphosphate carboxylase activity
BEP06_05430	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BEP06_05435	COG0235	Class ii aldolase
BEP06_05440	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BEP06_05445	COG3339	Conserved Protein
BEP06_05460	COG0542	response to heat
BEP06_05465	COG3949	Membrane
BEP06_05470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BEP06_05475	COG0720	synthase
BEP06_05480	COG0602	queuosine metabolic process
BEP06_05485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BEP06_05490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_05495	COG2217	Heavy metal translocating P-type atpase
BEP06_05505	COG0006	proline dipeptidase activity
BEP06_05515	COG1609	Transcriptional regulator
BEP06_05520	COG3711	transcriptional antiterminator
BEP06_05525	COG1263	PTS System
BEP06_05525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_05525	COG2190	(PTS) system
BEP06_05530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEP06_05535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BEP06_05540	COG0436	Aminotransferase
BEP06_05545	COG0583	DNA-binding transcription factor activity
BEP06_05550	COG0716	FMN binding
BEP06_05560	COG0716	FMN binding
BEP06_05565	COG2171	N-acyltransferase activity
BEP06_05570	COG1473	amidohydrolase
BEP06_05580	COG0668	transmembrane transport
BEP06_05585	COG0450	alkyl hydroperoxide reductase
BEP06_05590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_05605	COG0746	molybdenum cofactor guanylyltransferase activity
BEP06_05610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BEP06_05615	COG0303	'Molybdopterin
BEP06_05620	COG1763	Mo-molybdopterin cofactor biosynthetic process
BEP06_05625	COG0314	molybdopterin synthase activity
BEP06_05630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BEP06_05635	COG1132	(ABC) transporter
BEP06_05640	COG1132	(ABC) transporter
BEP06_05650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEP06_05655	COG1136	(ABC) transporter
BEP06_05660	COG0577	efflux transmembrane transporter activity
BEP06_05665	COG1349	DNA-binding transcription factor activity
BEP06_05670	COG1105	Belongs to the carbohydrate kinase PfkB family
BEP06_05675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEP06_05675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEP06_05675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEP06_05680	COG0681	Belongs to the peptidase S26 family
BEP06_05690	COG0488	(ABC) transporter
BEP06_05695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BEP06_05700	COG2309	aminopeptidase activity
BEP06_05710	COG1077	Cell shape determining protein MreB Mrl
BEP06_05715	COG2002	toxin-antitoxin pair type II binding
BEP06_05720	COG3852	Histidine kinase
BEP06_05725	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BEP06_05725	COG2105	PFAM AIG2 family protein
BEP06_05730	COG0569	domain protein
BEP06_05735	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BEP06_05740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BEP06_05750	COG0561	phosphatase activity
BEP06_05755	COG0242	peptide deformylase activity
BEP06_05765	COG0497	DNA recombination
BEP06_05770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BEP06_05775	COG0022	dehydrogenase e1 component
BEP06_05780	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEP06_05785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEP06_05790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_05795	COG1982	Orn Lys Arg decarboxylase major
BEP06_05810	COG1595	DNA-templated transcription, initiation
BEP06_05840	COG4896	Protein conserved in bacteria
BEP06_05850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BEP06_05855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BEP06_05860	COG2066	Belongs to the glutaminase family
BEP06_05865	COG4838	Belongs to the UPF0358 family
BEP06_05870	COG0772	Belongs to the SEDS family
BEP06_05875	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BEP06_05880	COG1612	heme a metabolic process
BEP06_05885	COG0109	protoheme IX farnesyltransferase activity
BEP06_05890	COG2010	Cytochrome c
BEP06_05890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BEP06_05895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BEP06_05900	COG1845	cytochrome c oxidase, subunit III
BEP06_05905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BEP06_05910	COG3336	cytochrome c oxidase
BEP06_05920	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BEP06_05925	COG2340	Cysteine-rich secretory protein family
BEP06_05940	COG3679	Belongs to the UPF0342 family
BEP06_05945	COG4471	UPF0298 protein
BEP06_05950	COG0742	ribosomal rna small subunit methyltransferase
BEP06_05955	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BEP06_05960	COG3314	Sporulation integral membrane protein YlbJ
BEP06_05965	COG1752	Esterase of the alpha-beta hydrolase superfamily
BEP06_05970	COG3480	Lon protease (S16) C-terminal proteolytic domain
BEP06_05975	COG1323	Belongs to the UPF0348 family
BEP06_05985	COG1399	metal-binding, possibly nucleic acid-binding protein
BEP06_05990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BEP06_06000	COG0454	-acetyltransferase
BEP06_06005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BEP06_06010	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BEP06_06015	COG2001	Belongs to the MraZ family
BEP06_06020	COG0275	rRNA processing
BEP06_06025	COG4839	cell division protein FtsL
BEP06_06040	COG0768	penicillin binding
BEP06_06050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BEP06_06060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BEP06_06065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BEP06_06070	COG0772	Belongs to the SEDS family
BEP06_06075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BEP06_06080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BEP06_06085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BEP06_06090	COG3879	Bacterial protein of unknown function (DUF881)
BEP06_06095	COG3879	Bacterial protein of unknown function (DUF881)
BEP06_06100	COG3856	small basic protein
BEP06_06105	COG0849	cell division
BEP06_06110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BEP06_06115	COG1119	ATPase activity
BEP06_06120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEP06_06125	COG1873	PFAM PRC-barrel domain
BEP06_06135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BEP06_06140	COG1799	cell septum assembly
BEP06_06145	COG0762	integral membrane protein
BEP06_06150	COG2302	S4 RNA-binding domain
BEP06_06155	COG3599	regulation of cell shape
BEP06_06160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BEP06_06165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BEP06_06170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BEP06_06175	COG0564	pseudouridine synthase activity
BEP06_06180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BEP06_06185	COG2233	PERMEase
BEP06_06190	COG0540	Belongs to the ATCase OTCase family
BEP06_06195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BEP06_06200	COG0505	Belongs to the CarA family
BEP06_06205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BEP06_06210	COG0543	2 iron, 2 sulfur cluster binding
BEP06_06215	COG0167	dihydroorotate dehydrogenase activity
BEP06_06220	COG0284	orotidine-5'-phosphate decarboxylase activity
BEP06_06225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BEP06_06230	COG1561	YicC-like family, N-terminal region
BEP06_06235	COG2052	Domain of unknown function (DUF370)
BEP06_06240	COG0194	GDP metabolic process
BEP06_06245	COG1758	RNA polymerase activity
BEP06_06250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BEP06_06255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BEP06_06260	COG0242	peptide deformylase activity
BEP06_06265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BEP06_06270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BEP06_06270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BEP06_06275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BEP06_06280	COG0631	protein serine/threonine phosphatase activity
BEP06_06285	COG2815	serine threonine protein kinase
BEP06_06285	COG0515	serine threonine protein kinase
BEP06_06290	COG1162	GTPase activity
BEP06_06295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BEP06_06300	COG1564	THIamine pyrophosphokinase
BEP06_06310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BEP06_06315	COG1302	Protein conserved in bacteria
BEP06_06320	COG1461	Dihydroxyacetone kinase
BEP06_06325	COG1760	l-serine dehydratase
BEP06_06330	COG1760	l-serine dehydratase
BEP06_06335	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BEP06_06340	COG1349	DNA-binding transcription factor activity
BEP06_06340	COG2050	protein possibly involved in aromatic compounds catabolism
BEP06_06345	COG0416	fatty acid biosynthetic process
BEP06_06350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BEP06_06355	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_06360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BEP06_06365	COG0571	ribonuclease III activity
BEP06_06370	COG1196	nuclear chromosome segregation
BEP06_06375	COG0552	protein localization to endoplasmic reticulum
BEP06_06385	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BEP06_06390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BEP06_06395	COG0228	four-way junction DNA binding
BEP06_06400	COG1837	Belongs to the UPF0109 family
BEP06_06410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BEP06_06415	COG0336	Belongs to the RNA methyltransferase TrmD family
BEP06_06420	COG0335	large ribosomal subunit rRNA binding
BEP06_06425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BEP06_06430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BEP06_06440	COG2257	FlhB HrpN YscU SpaS Family
BEP06_06445	COG0045	succinate-CoA ligase (ADP-forming) activity
BEP06_06450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BEP06_06455	COG0758	DNA mediated transformation
BEP06_06460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BEP06_06465	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BEP06_06470	COG4974	Belongs to the 'phage' integrase family
BEP06_06475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BEP06_06480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BEP06_06485	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BEP06_06490	COG1815	bacterial-type flagellum-dependent cell motility
BEP06_06495	COG1558	bacterial-type flagellum-dependent cell motility
BEP06_06500	COG1191	sigma factor activity
BEP06_06510	COG0052	Belongs to the universal ribosomal protein uS2 family
BEP06_06515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BEP06_06520	COG0528	UMP kinase activity
BEP06_06525	COG0233	cytoplasmic translational termination
BEP06_06530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BEP06_06535	COG4589	Belongs to the CDS family
BEP06_06540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BEP06_06545	COG0750	zinc metalloprotease
BEP06_06550	COG0442	prolyl-tRNA aminoacylation
BEP06_06555	COG2176	DNA-directed DNA polymerase activity
BEP06_06560	COG0779	Required for maturation of 30S ribosomal subunits
BEP06_06565	COG0195	Participates in both transcription termination and antitermination
BEP06_06570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BEP06_06575	COG1358	cellular component organization or biogenesis
BEP06_06580	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BEP06_06585	COG1550	Protein conserved in bacteria
BEP06_06590	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BEP06_06595	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BEP06_06600	COG0196	riboflavin kinase activity
BEP06_06605	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BEP06_06610	COG1185	polyribonucleotide nucleotidyltransferase activity
BEP06_06615	COG0726	polysaccharide deacetylase
BEP06_06620	COG0612	Peptidase, M16
BEP06_06625	COG1873	PFAM PRC-barrel domain
BEP06_06635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BEP06_06640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BEP06_06645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BEP06_06650	COG0527	aspartate kinase activity
BEP06_06655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BEP06_06660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BEP06_06665	COG0740	serine-type endopeptidase activity
BEP06_06675	COG4980	gas vesicle protein
BEP06_06675	COG1674	ftsk spoiiie
BEP06_06680	COG2188	Transcriptional regulator
BEP06_06685	COG2814	Major facilitator Superfamily
BEP06_06690	COG0612	Peptidase, M16
BEP06_06695	COG0612	Peptidase, M16
BEP06_06700	COG0300	oxidoreductase activity
BEP06_06715	COG1426	Protein conserved in bacteria
BEP06_06720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BEP06_06725	COG1058	Belongs to the CinA family
BEP06_06725	COG1546	Belongs to the CinA family
BEP06_06730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BEP06_06735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BEP06_06740	COG1418	mRNA catabolic process
BEP06_06745	COG1692	metallophosphoesterase
BEP06_06750	COG2359	stage V sporulation protein S
BEP06_06755	COG1063	alcohol dehydrogenase
BEP06_06760	COG0156	8-amino-7-oxononanoate synthase activity
BEP06_06765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BEP06_06770	COG4550	Control of competence regulator ComK, YlbF/YmcA
BEP06_06780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BEP06_06785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BEP06_06800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BEP06_06805	COG1923	regulation of RNA biosynthetic process
BEP06_06820	COG1780	Probably involved in ribonucleotide reductase function
BEP06_06825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BEP06_06830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BEP06_06835	COG4112	unkown
BEP06_06840	COG0860	N-Acetylmuramoyl-L-alanine amidase
BEP06_06845	COG0464	growth
BEP06_06855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BEP06_06860	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BEP06_06865	COG0789	Transcriptional regulator
BEP06_06870	COG0174	glutamine synthetase
BEP06_06875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BEP06_06880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BEP06_06885	COG1388	LysM domain
BEP06_06890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BEP06_06895	COG4224	UPF0291 protein
BEP06_06900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BEP06_06910	COG3763	UPF0154 protein
BEP06_06920	COG0785	Cytochrome C biogenesis protein
BEP06_06925	COG2201	protein-glutamate methylesterase activity
BEP06_06930	COG4846	Membrane protein involved in cytochrome C biogenesis
BEP06_06940	COG0071	Belongs to the small heat shock protein (HSP20) family
BEP06_06955	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BEP06_06960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_06980	COG0824	Thioesterase
BEP06_06990	COG4841	protein insertion into membrane
BEP06_06995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BEP06_07000	COG1832	CoA-binding protein
BEP06_07005	COG0187	DNA topoisomerase II activity
BEP06_07010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BEP06_07025	COG1115	amino acid carrier protein
BEP06_07030	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BEP06_07040	COG5520	Belongs to the glycosyl hydrolase 30 family
BEP06_07045	COG3507	Belongs to the glycosyl hydrolase 43 family
BEP06_07055	COG2246	polysaccharide biosynthetic process
BEP06_07060	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BEP06_07065	COG0586	Pfam SNARE associated Golgi protein
BEP06_07070	COG2404	hydrolase activity, acting on ester bonds
BEP06_07075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BEP06_07080	COG1024	Enoyl-CoA hydratase
BEP06_07085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BEP06_07090	COG0511	ligase activity, forming carbon-carbon bonds
BEP06_07095	COG0439	Biotin carboxylase
BEP06_07100	COG0318	PFAM AMP-dependent synthetase and ligase
BEP06_07105	COG1960	acyl-CoA dehydrogenase activity
BEP06_07120	COG1649	PFAM Uncharacterised BCR, COG1649
BEP06_07130	COG2027	D-alanyl-D-alanine carboxypeptidase
BEP06_07135	COG2017	converts alpha-aldose to the beta-anomer
BEP06_07140	COG0534	Mate efflux family protein
BEP06_07155	COG0582	viral genome integration into host DNA
BEP06_07160	COG0166	Belongs to the GPI family
BEP06_07165	COG0405	Gamma-glutamyltransferase
BEP06_07170	COG0583	DNA-binding transcription factor activity
BEP06_07175	COG0604	alcohol dehydrogenase
BEP06_07180	COG0493	'glutamate synthase
BEP06_07185	COG0067	glutamate synthase
BEP06_07185	COG0070	glutamate synthase
BEP06_07185	COG0069	glutamate synthase activity
BEP06_07190	COG0583	DNA-binding transcription factor activity
BEP06_07195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BEP06_07200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BEP06_07210	COG0300	oxidoreductase activity
BEP06_07215	COG3848	Pyruvate phosphate dikinase
BEP06_07215	COG0574	Belongs to the PEP-utilizing enzyme family
BEP06_07220	COG0726	polysaccharide deacetylase
BEP06_07225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEP06_07230	COG2207	Transcriptional regulator
BEP06_07230	COG0662	Cupin 2, conserved barrel domain protein
BEP06_07235	COG0456	acetyltransferase
BEP06_07240	COG1309	transcriptional regulator
BEP06_07245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEP06_07250	COG3708	Transcriptional regulator
BEP06_07255	COG2378	regulation of single-species biofilm formation
BEP06_07265	COG0640	Transcriptional regulator
BEP06_07270	COG0741	lytic transglycosylase activity
BEP06_07275	COG2322	membrane
BEP06_07290	COG1619	proteins homologs of microcin C7 resistance protein MccF
BEP06_07295	COG3239	Fatty acid desaturase
BEP06_07300	COG4585	Histidine kinase
BEP06_07305	COG2197	response regulator
BEP06_07310	COG1012	belongs to the aldehyde dehydrogenase family
BEP06_07315	COG1657	PFAM Prenyltransferase squalene oxidase
BEP06_07320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BEP06_07325	COG0733	neurotransmitter:sodium symporter activity
BEP06_07330	COG0385	Bile acid
BEP06_07335	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEP06_07340	COG0567	Dehydrogenase, E1 component
BEP06_07345	COG4548	von Willebrand factor, type A
BEP06_07350	COG0714	Associated with various cellular activities
BEP06_07355	COG2032	superoxide dismutase activity
BEP06_07360	COG0791	NLP P60 protein
BEP06_07360	COG1388	LysM domain
BEP06_07365	COG1819	glycosyl
BEP06_07370	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BEP06_07375	COG0534	Mate efflux family protein
BEP06_07380	COG1366	Belongs to the anti-sigma-factor antagonist family
BEP06_07385	COG0813	purine-nucleoside phosphorylase activity
BEP06_07390	COG1999	signal sequence binding
BEP06_07405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BEP06_07410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BEP06_07415	COG1272	protein, Hemolysin III
BEP06_07420	COG0204	Acyl-transferase
BEP06_07425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BEP06_07430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BEP06_07435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BEP06_07445	COG2521	methyltransferase
BEP06_07445	COG2136	Putative SAM-dependent methyltransferase
BEP06_07455	COG0129	dihydroxy-acid dehydratase activity
BEP06_07460	COG1413	lyase activity
BEP06_07465	COG1418	mRNA catabolic process
BEP06_07470	COG0386	Belongs to the glutathione peroxidase family
BEP06_07475	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BEP06_07480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BEP06_07485	COG1278	Cold shock
BEP06_07505	COG0328	RNA-DNA hybrid ribonuclease activity
BEP06_07510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BEP06_07515	COG0328	RNA-DNA hybrid ribonuclease activity
BEP06_07525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BEP06_07545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BEP06_07550	COG1755	Isoprenylcysteine carboxyl methyltransferase
BEP06_07555	COG3424	synthase
BEP06_07560	COG2233	PERMEase
BEP06_07565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEP06_07570	COG0116	Belongs to the methyltransferase superfamily
BEP06_07590	COG3331	DNA recombination
BEP06_07595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEP06_07595	COG4499	WXG100 protein secretion system (Wss), protein YukC
BEP06_07605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BEP06_07610	COG3935	DnaD domain protein
BEP06_07615	COG0017	Asparaginyl-tRNA synthetase
BEP06_07620	COG0436	Aminotransferase
BEP06_07625	COG5353	protein conserved in bacteria
BEP06_07635	COG1199	ATP-dependent helicase activity
BEP06_07635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEP06_07640	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BEP06_07645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BEP06_07650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BEP06_07655	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BEP06_07655	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BEP06_07660	COG0617	tRNA 3'-terminal CCA addition
BEP06_07665	COG0438	transferase activity, transferring glycosyl groups
BEP06_07670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BEP06_07675	COG1803	Methylglyoxal synthase
BEP06_07680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BEP06_07685	COG1694	Mazg nucleotide pyrophosphohydrolase
BEP06_07690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BEP06_07700	COG4347	Protein of unknown function (DUF1405)
BEP06_07705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BEP06_07705	COG2010	Cytochrome c
BEP06_07710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BEP06_07715	COG0723	plastoquinol--plastocyanin reductase activity
BEP06_07725	COG5582	Belongs to the UPF0302 family
BEP06_07730	COG0457	Tetratricopeptide repeat
BEP06_07735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BEP06_07740	COG0287	Prephenate dehydrogenase
BEP06_07745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BEP06_07750	COG0159	tryptophan synthase activity
BEP06_07755	COG0133	tryptophan synthase activity
BEP06_07760	COG0135	phosphoribosylanthranilate isomerase activity
BEP06_07770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BEP06_07775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BEP06_07780	COG4401	Chorismate mutase type I
BEP06_07785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BEP06_07790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BEP06_07795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BEP06_07805	COG0105	UTP biosynthetic process
BEP06_07810	COG0142	geranyltranstransferase activity
BEP06_07815	COG2226	methyltransferase
BEP06_07820	COG0142	geranyltranstransferase activity
BEP06_07830	COG0302	gtp cyclohydrolase
BEP06_07835	COG0776	regulation of translation
BEP06_07840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BEP06_07855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BEP06_07860	COG1160	GTP binding
BEP06_07885	COG1304	FMN binding
BEP06_07890	COG0539	negative regulation of cytoplasmic translation
BEP06_07895	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BEP06_07905	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BEP06_07910	COG2959	enzyme of heme biosynthesis
BEP06_07915	COG3409	Peptidoglycan-binding domain 1 protein
BEP06_07915	COG3773	Cell wall hydrolase
BEP06_07920	COG2339	peptidase activity
BEP06_07925	COG0492	ferredoxin-NADP+ reductase activity
BEP06_07930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEP06_07935	COG4862	establishment of competence for transformation
BEP06_07940	COG1408	metallophosphoesterase
BEP06_07950	COG1388	LysM domain
BEP06_07955	COG1266	CAAX protease self-immunity
BEP06_07960	COG0514	ATP-dependent DNA helicase (RecQ)
BEP06_07965	COG4955	Helix-turn-helix domain
BEP06_07970	COG1141	Ferredoxin
BEP06_07975	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BEP06_07980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BEP06_07985	COG0710	3-dehydroquinate dehydratase activity
BEP06_07995	COG1595	DNA-templated transcription, initiation
BEP06_08000	COG5002	protein histidine kinase activity
BEP06_08005	COG0745	RESPONSE REGULATOR receiver
BEP06_08010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BEP06_08015	COG1333	cytochrome c biogenesis protein
BEP06_08020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_08025	COG1187	pseudouridine synthase activity
BEP06_08030	COG0700	Nucleoside recognition
BEP06_08035	COG2715	membrane protein required for spore maturation
BEP06_08040	COG1686	Belongs to the peptidase S11 family
BEP06_08050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BEP06_08055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BEP06_08060	COG1547	Domain of unknown function (DUF309)
BEP06_08065	COG0456	acetyltransferase
BEP06_08070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BEP06_08075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BEP06_08075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BEP06_08080	COG0307	riboflavin synthase, alpha
BEP06_08085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEP06_08085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEP06_08095	COG0681	Belongs to the peptidase S26 family
BEP06_08100	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BEP06_08125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BEP06_08130	COG4086	secreted protein
BEP06_08135	COG0019	diaminopimelate decarboxylase activity
BEP06_08145	COG1686	Belongs to the peptidase S11 family
BEP06_08150	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BEP06_08155	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BEP06_08160	COG4974	Belongs to the 'phage' integrase family
BEP06_08170	COG0735	belongs to the Fur family
BEP06_08175	COG1300	Membrane
BEP06_08185	COG0281	malic enzyme
BEP06_08190	COG1757	Na H antiporter
BEP06_08195	COG1027	Aspartate ammonia-lyase
BEP06_08200	COG0252	asparaginase activity
BEP06_08205	COG1396	sequence-specific DNA binding
BEP06_08210	COG1379	DNA repair
BEP06_08215	COG0494	nUDIX hydrolase
BEP06_08225	COG0667	Aldo Keto reductase
BEP06_08235	COG1073	alpha beta
BEP06_08245	COG4918	Iron-sulphur cluster biosynthesis
BEP06_08250	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BEP06_08250	COG0456	acetyltransferase
BEP06_08255	COG2329	Antibiotic biosynthesis monooxygenase
BEP06_08260	COG0456	acetyltransferase
BEP06_08270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEP06_08280	COG2211	Major facilitator Superfamily
BEP06_08290	COG0346	lactoylglutathione lyase activity
BEP06_08295	COG1072	(Pantothenic acid kinase))
BEP06_08300	COG3048	D-serine ammonia-lyase activity
BEP06_08305	COG0300	oxidoreductase activity
BEP06_08310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEP06_08315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BEP06_08320	COG4187	Peptidase family M20/M25/M40
BEP06_08325	COG1902	pentaerythritol trinitrate reductase activity
BEP06_08330	COG0596	Alpha beta hydrolase
BEP06_08335	COG1234	tRNA 3'-trailer cleavage
BEP06_08340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BEP06_08345	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BEP06_08350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEP06_08360	COG0706	membrane insertase activity
BEP06_08365	COG3361	conserved protein (COG2071)
BEP06_08370	COG2195	Cleaves the N-terminal amino acid of tripeptides
BEP06_08375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BEP06_08380	COG0346	lactoylglutathione lyase activity
BEP06_08390	COG1376	ErfK ybiS ycfS ynhG family protein
BEP06_08395	COG4129	membrane
BEP06_08400	COG1126	abc transporter atp-binding protein
BEP06_08405	COG0765	amino acid transport
BEP06_08410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BEP06_08420	COG1597	lipid kinase activity
BEP06_08425	COG2814	Major facilitator Superfamily
BEP06_08430	COG4978	Transcriptional regulator
BEP06_08430	COG0789	Transcriptional regulator
BEP06_08435	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEP06_08440	COG0022	dehydrogenase e1 component
BEP06_08445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BEP06_08450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEP06_08455	COG3426	butyrate kinase activity
BEP06_08460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEP06_08465	COG0280	phosphate acetyltransferase
BEP06_08470	COG3290	protein histidine kinase activity
BEP06_08470	COG3829	transcription factor binding
BEP06_08480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BEP06_08485	COG2079	MmgE PrpD family protein
BEP06_08490	COG0372	Belongs to the citrate synthase family
BEP06_08495	COG1960	acyl-CoA dehydrogenase activity
BEP06_08500	COG1250	3-hydroxyacyl-CoA dehydrogenase
BEP06_08505	COG0183	Belongs to the thiolase family
BEP06_08510	COG0584	glycerophosphoryl diester phosphodiesterase
BEP06_08515	COG0860	N-Acetylmuramoyl-L-alanine amidase
BEP06_08530	COG1902	pentaerythritol trinitrate reductase activity
BEP06_08540	COG0745	RESPONSE REGULATOR receiver
BEP06_08550	COG0497	DNA recombination
BEP06_08555	COG1438	arginine binding
BEP06_08560	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BEP06_08565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BEP06_08570	COG0142	geranyltranstransferase activity
BEP06_08575	COG1722	exodeoxyribonuclease VII activity
BEP06_08580	COG1570	exodeoxyribonuclease VII activity
BEP06_08585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BEP06_08590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BEP06_08595	COG1302	Protein conserved in bacteria
BEP06_08600	COG0439	Biotin carboxylase
BEP06_08605	COG0511	ligase activity, forming carbon-carbon bonds
BEP06_08645	COG3854	ATPases associated with a variety of cellular activities
BEP06_08655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BEP06_08660	COG0006	proline dipeptidase activity
BEP06_08665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BEP06_08675	COG3872	metal-dependent enzyme
BEP06_08690	COG1321	iron dependent repressor
BEP06_08695	COG0095	Lipoate-protein ligase
BEP06_08700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BEP06_08705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BEP06_08710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BEP06_08715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BEP06_08720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BEP06_08735	COG1396	sequence-specific DNA binding
BEP06_08755	COG4940	Competence protein ComGF
BEP06_08765	COG4970	Tfp pilus assembly protein FimT
BEP06_08770	COG4537	Required for transformation and DNA binding
BEP06_08775	COG1459	type II secretion system
BEP06_08780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BEP06_08790	COG0598	Magnesium transport protein CorA
BEP06_08795	COG1253	flavin adenine dinucleotide binding
BEP06_08800	COG1366	Belongs to the anti-sigma-factor antagonist family
BEP06_08810	COG1393	Belongs to the ArsC family
BEP06_08820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEP06_08830	COG0011	TIGRFAM Protein of
BEP06_08840	COG2866	Carboxypeptidase
BEP06_08845	COG1368	sulfuric ester hydrolase activity
BEP06_08850	COG1940	carbohydrate kinase activity
BEP06_08855	COG4483	Protein conserved in bacteria
BEP06_08860	COG0705	Rhomboid family
BEP06_08860	COG0457	Tetratricopeptide repeat
BEP06_08870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BEP06_08875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BEP06_08880	COG0438	transferase activity, transferring glycosyl groups
BEP06_08895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BEP06_08900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BEP06_08905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BEP06_08910	COG0581	inorganic phosphate transmembrane transporter activity
BEP06_08915	COG0573	inorganic phosphate transmembrane transporter activity
BEP06_08920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BEP06_08930	COG0477	Major facilitator Superfamily
BEP06_08935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BEP06_08940	COG2839	Protein conserved in bacteria
BEP06_08945	COG5521	maltodextrose utilization protein MalA
BEP06_08955	COG1388	LysM domain
BEP06_08960	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BEP06_08965	COG4709	membrane
BEP06_08970	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BEP06_08975	COG0735	belongs to the Fur family
BEP06_08980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BEP06_08990	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BEP06_08995	COG0513	Belongs to the DEAD box helicase family
BEP06_09005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BEP06_09010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BEP06_09015	COG2384	SAM-dependent methyltransferase
BEP06_09020	COG2010	Cytochrome c
BEP06_09025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BEP06_09030	COG0358	DNA primase activity
BEP06_09035	COG1671	Belongs to the UPF0178 family
BEP06_09040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BEP06_09045	COG0517	IMP dehydrogenase activity
BEP06_09050	COG0751	glycine-tRNA ligase activity
BEP06_09055	COG0752	glycyl-tRNA synthetase alpha subunit
BEP06_09060	COG1381	Involved in DNA repair and RecF pathway recombination
BEP06_09070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BEP06_09075	COG0295	cytidine deaminase activity
BEP06_09080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BEP06_09085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BEP06_09090	COG1480	7TM receptor with intracellular HD hydrolase
BEP06_09100	COG1702	phosphate starvation-inducible protein PhoH
BEP06_09105	COG0561	phosphatase activity
BEP06_09120	COG4864	UPF0365 protein
BEP06_09125	COG1030	water channel activity
BEP06_09130	COG1610	YqeY-like protein
BEP06_09135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BEP06_09140	COG1283	sodium-dependent phosphate transmembrane transporter activity
BEP06_09145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BEP06_09150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BEP06_09155	COG2264	protein methyltransferase activity
BEP06_09160	COG0484	heat shock protein binding
BEP06_09165	COG0443	Heat shock 70 kDa protein
BEP06_09170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BEP06_09175	COG1420	regulation of RNA biosynthetic process
BEP06_09180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BEP06_09185	COG0481	GTPase activity
BEP06_09195	COG0860	N-Acetylmuramoyl-L-alanine amidase
BEP06_09200	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BEP06_09205	COG0268	Binds directly to 16S ribosomal RNA
BEP06_09210	COG1466	dna polymerase III delta subunit
BEP06_09220	COG0658	competence protein
BEP06_09220	COG2333	competence protein COMEC
BEP06_09225	COG2131	deaminase
BEP06_09230	COG1596	polysaccharide export
BEP06_09230	COG1555	photosystem II stabilization
BEP06_09235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BEP06_09240	COG2226	methyltransferase
BEP06_09245	COG0799	negative regulation of ribosome biogenesis
BEP06_09250	COG1713	HD superfamily hydrolase involved in NAD metabolism
BEP06_09255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BEP06_09260	COG1534	Rna-binding protein
BEP06_09265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BEP06_09270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BEP06_09275	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BEP06_09290	COG3223	Belongs to the PsiE family
BEP06_09295	COG5002	protein histidine kinase activity
BEP06_09295	COG0642	Histidine kinase
BEP06_09300	COG0745	RESPONSE REGULATOR receiver
BEP06_09305	COG2311	Membrane
BEP06_09315	COG0454	-acetyltransferase
BEP06_09320	COG2249	NAD(P)H dehydrogenase (quinone) activity
BEP06_09325	COG1595	DNA-templated transcription, initiation
BEP06_09330	COG0667	Aldo Keto reductase
BEP06_09335	COG2851	Citrate transporter
BEP06_09340	COG1113	amino acid transport
BEP06_09345	COG1280	lysine exporter protein (LysE YggA)
BEP06_09350	COG1378	Sugar-specific transcriptional regulator TrmB
BEP06_09355	COG1595	DNA-templated transcription, initiation
BEP06_09365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BEP06_09365	COG2755	lipolytic protein G-D-S-L family
BEP06_09375	COG2124	cytochrome p450
BEP06_09375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BEP06_09380	COG1309	transcriptional regulator
BEP06_09385	COG2226	methyltransferase
BEP06_09395	COG2116	formate transmembrane transporter activity
BEP06_09400	COG5609	conserved protein (DUF2294)
BEP06_09405	COG3383	formate dehydrogenase (NAD+) activity
BEP06_09410	COG2427	Protein of unknown function (DUF1641)
BEP06_09420	COG0626	cystathionine gamma-synthase activity
BEP06_09425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BEP06_09430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BEP06_09435	COG2226	methyltransferase
BEP06_09450	COG0768	penicillin binding
BEP06_09455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BEP06_09460	COG0572	uridine kinase
BEP06_09480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BEP06_09485	COG3906	Belongs to the UPF0473 family
BEP06_09490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BEP06_09495	COG4472	Bacterial protein of unknown function (DUF965)
BEP06_09500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BEP06_09505	COG0628	permease
BEP06_09510	COG1126	abc transporter atp-binding protein
BEP06_09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BEP06_09520	COG0765	amino acid transport
BEP06_09525	COG0765	amino acid transport
BEP06_09540	COG3881	PFAM PRC-barrel domain
BEP06_09545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEP06_09550	COG0457	Tetratricopeptide repeat
BEP06_09555	COG0482	sulfurtransferase activity
BEP06_09560	COG1104	cysteine desulfurase activity
BEP06_09565	COG1959	2 iron, 2 sulfur cluster binding
BEP06_09570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BEP06_09575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BEP06_09585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BEP06_09590	COG0124	histidyl-tRNA synthetase
BEP06_09600	COG3103	Sh3 type 3 domain protein
BEP06_09600	COG4991	sh3 domain protein
BEP06_09600	COG0860	N-Acetylmuramoyl-L-alanine amidase
BEP06_09605	COG1490	D-aminoacyl-tRNA deacylase activity
BEP06_09610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BEP06_09615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEP06_09620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BEP06_09620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BEP06_09625	COG5416	Lipopolysaccharide assembly protein A domain
BEP06_09630	COG0490	domain, Protein
BEP06_09635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BEP06_09635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BEP06_09645	COG2244	polysaccharide biosynthetic process
BEP06_09650	COG2323	membrane
BEP06_09660	COG1862	Preprotein translocase
BEP06_09665	COG0343	queuine tRNA-ribosyltransferase activity
BEP06_09670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BEP06_09680	COG2255	four-way junction helicase activity
BEP06_09685	COG0632	four-way junction helicase activity
BEP06_09695	COG2814	Major facilitator Superfamily
BEP06_09700	COG0673	inositol 2-dehydrogenase activity
BEP06_09705	COG2112	serine threonine protein kinase
BEP06_09725	COG1115	amino acid carrier protein
BEP06_09730	COG0217	transcriptional regulatory protein
BEP06_09740	COG1388	LysM domain
BEP06_09745	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BEP06_09750	COG0157	Belongs to the NadC ModD family
BEP06_09755	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BEP06_09760	COG1104	cysteine desulfurase activity
BEP06_09765	COG1827	regulation of RNA biosynthetic process
BEP06_09770	COG0077	Prephenate dehydratase
BEP06_09775	COG4492	Belongs to the UPF0735 family
BEP06_09780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BEP06_09785	COG3290	protein histidine kinase activity
BEP06_09795	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BEP06_09800	COG2868	ribosomal protein
BEP06_09805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BEP06_09810	COG1994	Peptidase M50
BEP06_09815	COG0739	heme binding
BEP06_09820	COG2894	cell division
BEP06_09825	COG0850	regulation of cytokinetic process
BEP06_09830	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BEP06_09835	COG1792	Involved in formation and maintenance of cell shape
BEP06_09840	COG1077	Cell shape determining protein MreB Mrl
BEP06_09845	COG2003	Belongs to the UPF0758 family
BEP06_09850	COG0424	maF-like protein
BEP06_09860	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BEP06_09865	COG0285	dihydrofolate synthase activity
BEP06_09870	COG0525	valine-tRNA ligase activity
BEP06_09880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BEP06_09885	COG1388	LysM domain
BEP06_09890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BEP06_09895	COG0113	porphobilinogen synthase activity
BEP06_09900	COG1587	Uroporphyrinogen-III synthase
BEP06_09905	COG0181	hydroxymethylbilane synthase activity
BEP06_09910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BEP06_09915	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BEP06_09925	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BEP06_09930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BEP06_09935	COG0470	DNA polymerase III
BEP06_09935	COG1067	ATP-dependent peptidase activity
BEP06_09940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BEP06_09945	COG0544	peptidyl-prolyl cis-trans isomerase activity
BEP06_09950	COG1477	protein flavinylation
BEP06_09950	COG0457	Tetratricopeptide repeat
BEP06_09955	COG0066	3-isopropylmalate dehydratase activity
BEP06_09960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BEP06_09965	COG0473	3-isopropylmalate dehydrogenase activity
BEP06_09970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BEP06_09975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BEP06_09980	COG0440	acetolactate synthase activity
BEP06_09985	COG0028	Belongs to the TPP enzyme family
BEP06_09995	COG0454	-acetyltransferase
BEP06_10005	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BEP06_10015	COG0622	Phosphoesterase
BEP06_10020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BEP06_10025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BEP06_10030	COG5401	PFAM Sporulation and spore germination
BEP06_10035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BEP06_10040	COG1846	Transcriptional regulator
BEP06_10045	COG2197	response regulator
BEP06_10050	COG0824	Thioesterase
BEP06_10055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BEP06_10060	COG1053	succinate dehydrogenase
BEP06_10065	COG2009	succinate dehydrogenase
BEP06_10075	COG1719	4-vinyl reductase, 4VR
BEP06_10080	COG0527	aspartate kinase activity
BEP06_10085	COG0322	excinuclease ABC activity
BEP06_10090	COG3118	belongs to the thioredoxin family
BEP06_10095	COG3534	alpha-L-arabinofuranosidase
BEP06_10100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BEP06_10105	COG2086	electron transfer activity
BEP06_10110	COG1024	Enoyl-CoA hydratase
BEP06_10115	COG1309	transcriptional regulator
BEP06_10120	COG0318	PFAM AMP-dependent synthetase and ligase
BEP06_10125	COG3766	membrane
BEP06_10130	COG1193	negative regulation of DNA recombination
BEP06_10135	COG1796	DNA polymerase
BEP06_10135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BEP06_10140	COG1286	toxin biosynthetic process
BEP06_10145	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BEP06_10150	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BEP06_10155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEP06_10155	COG0072	phenylalanine-tRNA ligase activity
BEP06_10160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BEP06_10170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEP06_10175	COG3326	Membrane
BEP06_10180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BEP06_10185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BEP06_10190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BEP06_10200	COG1346	cytolysis
BEP06_10205	COG1380	Effector of murein hydrolase LrgA
BEP06_10210	COG3279	Response regulator of the LytR AlgR family
BEP06_10215	COG3275	phosphorelay sensor kinase activity
BEP06_10225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BEP06_10235	COG0398	Pfam SNARE associated Golgi protein
BEP06_10240	COG1484	DNA-dependent DNA replication
BEP06_10245	COG3611	Membrane attachment protein
BEP06_10250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BEP06_10255	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BEP06_10260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BEP06_10265	COG1733	regulation of RNA biosynthetic process
BEP06_10270	COG2814	Major facilitator Superfamily
BEP06_10275	COG0656	L-ascorbic acid biosynthetic process
BEP06_10280	COG0237	dephospho-CoA kinase activity
BEP06_10295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BEP06_10300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BEP06_10300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BEP06_10305	COG5002	protein histidine kinase activity
BEP06_10310	COG0745	RESPONSE REGULATOR receiver
BEP06_10315	COG0039	L-malate dehydrogenase activity
BEP06_10320	COG0538	isocitrate dehydrogenase activity
BEP06_10325	COG0372	Belongs to the citrate synthase family
BEP06_10330	COG2707	UPF0756 membrane protein
BEP06_10335	COG0628	permease
BEP06_10340	COG3030	protein affecting phage T7 exclusion by the F plasmid
BEP06_10345	COG0469	pyruvate kinase activity
BEP06_10350	COG0205	6-phosphofructokinase activity
BEP06_10355	COG0825	malonyl-CoA metabolic process
BEP06_10360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BEP06_10365	COG0281	malic enzyme
BEP06_10370	COG0587	DNA-directed DNA polymerase activity
BEP06_10390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BEP06_10400	COG4109	DRTGG domain
BEP06_10410	COG0730	response to heat
BEP06_10415	COG1473	amidohydrolase
BEP06_10420	COG0196	riboflavin kinase activity
BEP06_10425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEP06_10430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BEP06_10435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEP06_10440	COG1126	abc transporter atp-binding protein
BEP06_10445	COG0765	amino acid transport
BEP06_10450	COG0765	amino acid transport
BEP06_10455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BEP06_10460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BEP06_10465	COG0454	-acetyltransferase
BEP06_10470	COG0583	DNA-binding transcription factor activity
BEP06_10475	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BEP06_10480	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_10490	COG0165	Argininosuccinate lyase
BEP06_10495	COG0137	argininosuccinate synthase activity
BEP06_10500	COG0521	Mo-molybdopterin cofactor biosynthetic process
BEP06_10505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BEP06_10510	COG0827	DNA restriction-modification system
BEP06_10515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BEP06_10520	COG3874	Sporulation protein YtfJ
BEP06_10530	COG1714	RDD family
BEP06_10535	COG0616	signal peptide processing
BEP06_10540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BEP06_10545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BEP06_10550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEP06_10560	COG0301	tRNA thio-modification
BEP06_10565	COG1104	cysteine desulfurase activity
BEP06_10570	COG1114	Component of the transport system for branched-chain amino acids
BEP06_10575	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BEP06_10580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BEP06_10585	COG1309	transcriptional regulator
BEP06_10590	COG1956	GAF domain-containing protein
BEP06_10595	COG2199	diguanylate cyclase activity
BEP06_10595	COG2203	Gaf domain
BEP06_10600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BEP06_10610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BEP06_10615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEP06_10620	COG0454	-acetyltransferase
BEP06_10625	COG0517	IMP dehydrogenase activity
BEP06_10630	COG0123	including yeast histone deacetylase and acetoin utilization protein
BEP06_10635	COG1360	Flagellar Motor Protein
BEP06_10640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BEP06_10645	COG1609	Transcriptional regulator
BEP06_10650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BEP06_10650	COG1605	Chorismate mutase
BEP06_10655	COG3118	belongs to the thioredoxin family
BEP06_10660	COG4980	gas vesicle protein
BEP06_10665	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BEP06_10670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BEP06_10675	COG1674	ftsk spoiiie
BEP06_10680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEP06_10685	COG4848	Belongs to the UPF0354 family
BEP06_10690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_10700	COG1363	Peptidase, m42
BEP06_10705	COG5584	Small secreted protein
BEP06_10710	COG0281	malic enzyme
BEP06_10715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEP06_10720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BEP06_10730	COG0510	thiamine kinase activity
BEP06_10735	COG1523	belongs to the glycosyl hydrolase 13 family
BEP06_10740	COG1597	lipid kinase activity
BEP06_10750	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BEP06_10755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BEP06_10760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEP06_10765	COG2252	PERMEase
BEP06_10770	COG4473	ABC transporter
BEP06_10775	COG1131	(ABC) transporter
BEP06_10780	COG1349	DNA-binding transcription factor activity
BEP06_10785	COG1187	pseudouridine synthase activity
BEP06_10790	COG2244	polysaccharide biosynthetic process
BEP06_10795	COG2081	HI0933 family
BEP06_10800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BEP06_10810	COG5578	integral membrane protein
BEP06_10815	COG0673	inositol 2-dehydrogenase activity
BEP06_10820	COG1653	transport
BEP06_10825	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BEP06_10835	COG2207	Transcriptional regulator
BEP06_10840	COG1653	transport
BEP06_10845	COG0395	ABC-type sugar transport system, permease component
BEP06_10850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BEP06_10855	COG2124	cytochrome p450
BEP06_10860	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BEP06_10865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BEP06_10870	COG0156	8-amino-7-oxononanoate synthase activity
BEP06_10875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BEP06_10880	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
BEP06_10885	COG1073	alpha beta
BEP06_10910	COG1486	melibiose metabolic process
BEP06_10915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BEP06_10920	COG0495	leucyl-tRNA aminoacylation
BEP06_10930	COG1366	Belongs to the anti-sigma-factor antagonist family
BEP06_10930	COG2202	Pas domain
BEP06_10940	COG1113	amino acid transport
BEP06_10945	COG0367	asparagine synthase
BEP06_10950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BEP06_10955	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BEP06_10965	COG1506	peptidase
BEP06_10970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BEP06_10975	COG1116	anion transmembrane transporter activity
BEP06_10980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BEP06_10985	COG0494	nUDIX hydrolase
BEP06_10990	COG4824	toxin secretion phage lysis holin
BEP06_10995	COG0783	Belongs to the Dps family
BEP06_11010	COG1854	S-ribosylhomocysteine lyase activity
BEP06_11015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BEP06_11020	COG0288	reversible hydration of carbon dioxide
BEP06_11025	COG0254	rRNA binding
BEP06_11030	COG1271	oxidase subunit
BEP06_11035	COG1294	oxidase, subunit
BEP06_11045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BEP06_11050	COG1321	iron dependent repressor
BEP06_11050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BEP06_11055	COG1121	(ABC) transporter
BEP06_11060	COG0803	Belongs to the bacterial solute-binding protein 9 family
BEP06_11065	COG4948	Mandelate Racemase Muconate Lactonizing
BEP06_11070	COG0318	PFAM AMP-dependent synthetase and ligase
BEP06_11075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BEP06_11080	COG0596	Alpha beta hydrolase
BEP06_11085	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BEP06_11090	COG1169	isochorismate synthase
BEP06_11095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BEP06_11100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BEP06_11105	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BEP06_11110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BEP06_11115	COG0438	transferase activity, transferring glycosyl groups
BEP06_11125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BEP06_11130	COG0438	transferase activity, transferring glycosyl groups
BEP06_11135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BEP06_11140	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BEP06_11145	COG0058	SHG alpha-glucan phosphorylase activity
BEP06_11150	COG0297	glycogen (starch) synthase activity
BEP06_11155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BEP06_11160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BEP06_11165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BEP06_11295	COG3859	Proton-coupled thiamine transporter YuaJ
BEP06_11300	COG1247	-acetyltransferase
BEP06_11305	COG2268	Band 7 protein
BEP06_11310	COG1585	Membrane protein implicated in regulation of membrane protease activity
BEP06_11315	COG2318	DinB family
BEP06_11325	COG1454	alcohol dehydrogenase
BEP06_11335	COG1510	regulation of RNA biosynthetic process
BEP06_11340	COG1396	sequence-specific DNA binding
BEP06_11345	COG0569	domain protein
BEP06_11350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BEP06_11355	COG4682	membrane
BEP06_11360	COG1705	Flagellar rod assembly protein muramidase FlgJ
BEP06_11365	COG0477	Major facilitator Superfamily
BEP06_11370	COG5553	Cysteine dioxygenase type I
BEP06_11380	COG1968	undecaprenyl-diphosphatase activity
BEP06_11385	COG0628	permease
BEP06_11390	COG0673	inositol 2-dehydrogenase activity
BEP06_11395	COG0166	Belongs to the GPI family
BEP06_11400	COG1979	alcohol dehydrogenase
BEP06_11405	COG1979	alcohol dehydrogenase
BEP06_11410	COG2155	Conserved Protein
BEP06_11415	COG1098	S1 RNA binding domain
BEP06_11420	COG0436	Aminotransferase
BEP06_11425	COG1522	sequence-specific DNA binding
BEP06_11430	COG2267	carboxylic ester hydrolase activity
BEP06_11440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BEP06_11445	COG2205	protein histidine kinase activity
BEP06_11455	COG5018	Exonuclease
BEP06_11465	COG2814	Major facilitator Superfamily
BEP06_11470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEP06_11475	COG3011	Protein conserved in bacteria
BEP06_11485	COG3290	protein histidine kinase activity
BEP06_11490	COG4565	transcriptional regulatory protein
BEP06_11515	COG3493	citrate carrier protein
BEP06_11525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BEP06_11525	COG2111	Na H antiporter
BEP06_11530	COG2111	Na H antiporter
BEP06_11535	COG1006	Multisubunit Na H antiporter MnhC subunit
BEP06_11540	COG0651	ATP synthesis coupled electron transport
BEP06_11545	COG1863	multisubunit Na H antiporter MnhE subunit
BEP06_11550	COG2212	antiporter activity
BEP06_11555	COG1320	monovalent cation:proton antiporter activity
BEP06_11560	COG2050	protein possibly involved in aromatic compounds catabolism
BEP06_11575	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BEP06_11580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BEP06_11585	COG1335	isochorismatase
BEP06_11590	COG3251	PFAM MbtH domain protein
BEP06_11595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEP06_11600	COG1535	isochorismatase
BEP06_11600	COG3433	isochorismatase activity
BEP06_11605	COG1021	2,3-dihydroxybenzoate-AMP ligase
BEP06_11610	COG1169	isochorismate synthase
BEP06_11615	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_11620	COG2819	hydrolase of the alpha beta superfamily
BEP06_11625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BEP06_11630	COG1268	BioY protein
BEP06_11635	COG2056	Na+-H+ antiporter family
BEP06_11640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BEP06_11645	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BEP06_11650	COG3584	3D domain protein
BEP06_11665	COG1252	NADH dehydrogenase
BEP06_11670	COG0492	ferredoxin-NADP+ reductase activity
BEP06_11680	COG0516	GMP reductase activity
BEP06_11685	COG2808	Putative FMN-binding domain
BEP06_11690	COG0456	acetyltransferase
BEP06_11695	COG0316	Belongs to the HesB IscA family
BEP06_11700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BEP06_11705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BEP06_11710	COG4844	belongs to the
BEP06_11715	COG1252	NADH dehydrogenase
BEP06_11720	COG4837	Protein of unknown function (DUF1462)
BEP06_11725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BEP06_11730	COG0823	Involved in the tonB-independent uptake of proteins
BEP06_11730	COG1506	peptidase
BEP06_11730	COG4946	Tricorn protease homolog
BEP06_11735	COG0083	homoserine kinase activity
BEP06_11740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BEP06_11745	COG0460	homoserine dehydrogenase
BEP06_11750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BEP06_11755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BEP06_11760	COG0647	UMP catabolic process
BEP06_11765	COG2445	Protein of unknown function DUF86
BEP06_11770	COG4470	Protein conserved in bacteria
BEP06_11780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BEP06_11785	COG0719	Fe-S assembly protein
BEP06_11790	COG0822	iron-sulfur transferase activity
BEP06_11795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BEP06_11800	COG0719	Fe-S assembly protein
BEP06_11805	COG0396	ATPase activity
BEP06_11815	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BEP06_11820	COG1464	Belongs to the NlpA lipoprotein family
BEP06_11825	COG2011	ABC-type metal ion transport system permease component
BEP06_11830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BEP06_11840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEP06_11845	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BEP06_11855	COG0509	glycine decarboxylation via glycine cleavage system
BEP06_11860	COG1393	Belongs to the ArsC family
BEP06_11865	COG1960	acyl-CoA dehydrogenase activity
BEP06_11870	COG0183	Belongs to the thiolase family
BEP06_11875	COG1024	Enoyl-CoA hydratase
BEP06_11875	COG1250	3-hydroxyacyl-CoA dehydrogenase
BEP06_11885	COG0506	proline dehydrogenase activity
BEP06_11895	COG5577	PFAM Coat F domain
BEP06_11900	COG1846	Transcriptional regulator
BEP06_11905	COG0477	Major facilitator Superfamily
BEP06_11910	COG1942	4-Oxalocrotonate Tautomerase
BEP06_11915	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_11920	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_11935	COG1120	ATPase activity
BEP06_11955	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_11960	COG0783	Belongs to the Dps family
BEP06_11965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEP06_11970	COG0745	RESPONSE REGULATOR receiver
BEP06_11975	COG2770	Histidine kinase
BEP06_11975	COG2205	protein histidine kinase activity
BEP06_11985	COG1309	transcriptional regulator
BEP06_11990	COG0114	fumarate hydratase activity
BEP06_11995	COG2197	response regulator
BEP06_12000	COG4585	Histidine kinase
BEP06_12005	COG4758	membrane
BEP06_12010	COG3595	metallopeptidase activity
BEP06_12015	COG1842	Phage shock protein A
BEP06_12020	COG4758	membrane
BEP06_12025	COG2814	Major facilitator Superfamily
BEP06_12030	COG2096	Adenosyltransferase
BEP06_12035	COG1120	ATPase activity
BEP06_12040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_12045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEP06_12050	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_12055	COG3386	PFAM SMP-30 Gluconolaconase
BEP06_12060	COG2205	protein histidine kinase activity
BEP06_12065	COG0745	RESPONSE REGULATOR receiver
BEP06_12075	COG1191	sigma factor activity
BEP06_12085	COG2140	Oxalate decarboxylase
BEP06_12095	COG0577	efflux transmembrane transporter activity
BEP06_12100	COG1136	(ABC) transporter
BEP06_12105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BEP06_12110	COG1120	ATPase activity
BEP06_12115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_12120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEP06_12125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEP06_12135	COG0531	amino acid
BEP06_12145	COG1988	membrane-bound metal-dependent
BEP06_12150	COG1368	sulfuric ester hydrolase activity
BEP06_12155	COG1910	domain protein
BEP06_12160	COG0725	ABC transporter, periplasmic molybdate-binding protein
BEP06_12165	COG4149	molybdate abc transporter
BEP06_12170	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BEP06_12175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BEP06_12180	COG2217	Heavy metal translocating P-type atpase
BEP06_12185	COG2217	Heavy metal translocating P-type atpase
BEP06_12190	COG2608	mercury ion transmembrane transporter activity
BEP06_12195	COG1937	Protein conserved in bacteria
BEP06_12200	COG0673	inositol 2-dehydrogenase activity
BEP06_12205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BEP06_12210	COG1289	transmembrane transporter activity
BEP06_12220	COG2076	Multidrug Resistance protein
BEP06_12225	COG1309	transcriptional regulator
BEP06_12230	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_12240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BEP06_12245	COG0557	exoribonuclease II activity
BEP06_12250	COG1647	Serine aminopeptidase, S33
BEP06_12255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BEP06_12260	COG0596	Alpha beta hydrolase
BEP06_12265	COG1476	TRANSCRIPTIONal
BEP06_12270	COG1396	sequence-specific DNA binding
BEP06_12275	COG1396	sequence-specific DNA binding
BEP06_12280	COG1733	regulation of RNA biosynthetic process
BEP06_12285	COG0840	transmembrane signaling receptor activity
BEP06_12290	COG1174	glycine betaine transport
BEP06_12295	COG1732	Glycine betaine
BEP06_12300	COG1174	glycine betaine transport
BEP06_12305	COG0517	IMP dehydrogenase activity
BEP06_12305	COG1125	glycine betaine transport
BEP06_12310	COG1510	regulation of RNA biosynthetic process
BEP06_12315	COG1174	glycine betaine transport
BEP06_12320	COG1732	Glycine betaine
BEP06_12325	COG1174	glycine betaine transport
BEP06_12330	COG1125	glycine betaine transport
BEP06_12330	COG0517	IMP dehydrogenase activity
BEP06_12335	COG1510	regulation of RNA biosynthetic process
BEP06_12340	COG2095	MarC family integral membrane protein
BEP06_12350	COG3064	Membrane
BEP06_12355	COG4640	response to antibiotic
BEP06_12360	COG0456	acetyltransferase
BEP06_12365	COG0148	phosphopyruvate hydratase activity
BEP06_12370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BEP06_12375	COG0149	triose-phosphate isomerase activity
BEP06_12380	COG0126	phosphoglycerate kinase activity
BEP06_12390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BEP06_12395	COG2390	Transcriptional regulator
BEP06_12400	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BEP06_12410	COG2272	Belongs to the type-B carboxylesterase lipase family
BEP06_12425	COG0740	serine-type endopeptidase activity
BEP06_12430	COG1481	regulation of sporulation
BEP06_12435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BEP06_12440	COG1660	Displays ATPase and GTPase activities
BEP06_12445	COG1051	belongs to the nudix hydrolase family
BEP06_12450	COG0492	ferredoxin-NADP+ reductase activity
BEP06_12455	COG3883	PFAM NLP P60 protein
BEP06_12455	COG0791	NLP P60 protein
BEP06_12460	COG0457	Tetratricopeptide repeat
BEP06_12465	COG1132	(ABC) transporter
BEP06_12485	COG4903	ComK protein
BEP06_12490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEP06_12495	COG0140	phosphoribosyl-ATP diphosphatase activity
BEP06_12495	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BEP06_12500	COG0107	imidazoleglycerol-phosphate synthase activity
BEP06_12505	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BEP06_12510	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BEP06_12515	COG0131	Imidazoleglycerol-phosphate dehydratase
BEP06_12520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BEP06_12525	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BEP06_12530	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BEP06_12535	COG4990	cell redox homeostasis
BEP06_12540	COG5297	Belongs to the glycosyl hydrolase family 6
BEP06_12545	COG0110	maltose O-acetyltransferase activity
BEP06_12550	COG0546	phosphoglycolate phosphatase activity
BEP06_12555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BEP06_12560	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BEP06_12565	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BEP06_12570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BEP06_12575	COG0556	nucleotide-excision repair
BEP06_12580	COG4897	Protein conserved in bacteria
BEP06_12585	COG3848	Pyruvate phosphate dikinase
BEP06_12585	COG0574	Belongs to the PEP-utilizing enzyme family
BEP06_12590	COG1309	transcriptional regulator
BEP06_12595	COG2814	Major facilitator Superfamily
BEP06_12600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEP06_12610	COG3409	Peptidoglycan-binding domain 1 protein
BEP06_12610	COG0793	Belongs to the peptidase S41A family
BEP06_12615	COG2177	Part of the ABC transporter FtsEX involved in
BEP06_12620	COG2884	Cell division ATP-binding protein ftsE
BEP06_12625	COG2010	Cytochrome c
BEP06_12630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BEP06_12635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BEP06_12640	COG0653	protein targeting
BEP06_12645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BEP06_12650	COG3418	PFAM FlgN family protein
BEP06_12655	COG2747	anti-sigma28 factor FlgM
BEP06_12665	COG1040	competence protein
BEP06_12675	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BEP06_12680	COG1307	EDD domain protein, DegV family
BEP06_12685	COG2197	response regulator
BEP06_12690	COG4585	Histidine kinase
BEP06_12695	COG1739	Uncharacterized protein family UPF0029
BEP06_12700	COG1316	TRANSCRIPTIONal
BEP06_12705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BEP06_12710	COG0438	transferase activity, transferring glycosyl groups
BEP06_12715	COG1215	transferase activity, transferring glycosyl groups
BEP06_12720	COG3206	protein involved in exopolysaccharide biosynthesis
BEP06_12725	COG3307	-O-antigen
BEP06_12730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BEP06_12735	COG0438	transferase activity, transferring glycosyl groups
BEP06_12735	COG0297	glycogen (starch) synthase activity
BEP06_12740	COG2244	polysaccharide biosynthetic process
BEP06_12745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BEP06_12755	COG2247	cell wall binding repeat
BEP06_12755	COG0860	N-Acetylmuramoyl-L-alanine amidase
BEP06_12760	COG2247	cell wall binding repeat
BEP06_12760	COG2385	sporulation resulting in formation of a cellular spore
BEP06_12770	COG1316	TRANSCRIPTIONal
BEP06_12775	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BEP06_12780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BEP06_12790	COG0463	Glycosyl transferase, family 2
BEP06_12805	COG1134	teichoic acid transport
BEP06_12810	COG1682	transport, permease protein
BEP06_12815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEP06_12820	COG0438	transferase activity, transferring glycosyl groups
BEP06_12825	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BEP06_12830	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BEP06_12835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEP06_12845	COG2249	NAD(P)H dehydrogenase (quinone) activity
BEP06_12850	COG3527	Alpha-acetolactate decarboxylase
BEP06_12855	COG0028	Belongs to the TPP enzyme family
BEP06_12860	COG0583	DNA-binding transcription factor activity
BEP06_12865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BEP06_12870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BEP06_12875	COG4464	protein tyrosine phosphatase activity
BEP06_12880	COG0489	protein tyrosine kinase activity
BEP06_12885	COG3944	biosynthesis protein
BEP06_12895	COG4715	Zinc finger, swim domain protein
BEP06_12900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BEP06_12905	COG0561	phosphatase activity
BEP06_12910	COG1349	DNA-binding transcription factor activity
BEP06_12915	COG0629	single-stranded DNA binding
BEP06_12930	COG3764	Sortase (surface protein transpeptidase)
BEP06_12935	COG2972	Histidine kinase
BEP06_12935	COG0745	RESPONSE REGULATOR receiver
BEP06_12940	COG1970	mechanosensitive ion channel activity
BEP06_12945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BEP06_12950	COG0457	Tetratricopeptide repeat
BEP06_12955	COG4786	Flagellar basal body rod
BEP06_12960	COG4786	Flagellar basal body rod
BEP06_12965	COG1077	Cell shape determining protein MreB Mrl
BEP06_12970	COG1609	Transcriptional regulator
BEP06_12975	COG1846	Transcriptional regulator
BEP06_12980	COG2814	Major facilitator Superfamily
BEP06_12985	COG3420	alginic acid biosynthetic process
BEP06_12990	COG1953	Uracil, thiamine, allantoin
BEP06_12995	COG0477	Major facilitator Superfamily
BEP06_13000	COG1335	isochorismatase
BEP06_13010	COG0004	ammonium transporteR
BEP06_13015	COG0347	Belongs to the P(II) protein family
BEP06_13020	COG0671	phosphoesterase, PA-phosphatase related
BEP06_13030	COG0739	heme binding
BEP06_13035	COG1247	-acetyltransferase
BEP06_13055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEP06_13060	COG0789	Transcriptional regulator
BEP06_13070	COG2910	NAD(P)H-binding
BEP06_13075	COG1959	2 iron, 2 sulfur cluster binding
BEP06_13080	COG0804	urea catabolic process
BEP06_13085	COG0832	Belongs to the urease beta subunit family
BEP06_13090	COG0831	urea catabolic process
BEP06_13100	COG3237	CsbD-like
BEP06_13105	COG1994	Peptidase M50
BEP06_13110	COG0457	Tetratricopeptide repeat
BEP06_13115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BEP06_13120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BEP06_13130	COG2304	oxidoreductase activity
BEP06_13140	COG2304	oxidoreductase activity
BEP06_13145	COG2385	sporulation resulting in formation of a cellular spore
BEP06_13150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BEP06_13160	COG4836	Membrane
BEP06_13170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BEP06_13175	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BEP06_13180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BEP06_13185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BEP06_13190	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BEP06_13195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BEP06_13205	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BEP06_13210	COG0356	it plays a direct role in the translocation of protons across the membrane
BEP06_13220	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BEP06_13225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BEP06_13230	COG4475	Protein of unknown function (DUF436)
BEP06_13235	COG0698	ribose 5-phosphate isomerase
BEP06_13240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEP06_13245	COG1971	Probably functions as a manganese efflux pump
BEP06_13250	COG0009	L-threonylcarbamoyladenylate synthase
BEP06_13255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BEP06_13275	COG2890	protein-(glutamine-N5) methyltransferase activity
BEP06_13280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BEP06_13285	COG0346	lactoylglutathione lyase activity
BEP06_13290	COG0789	Transcriptional regulator
BEP06_13295	COG0679	Auxin Efflux Carrier
BEP06_13300	COG0281	malic enzyme
BEP06_13305	COG1435	thymidine kinase activity
BEP06_13310	COG0254	rRNA binding
BEP06_13315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BEP06_13325	COG1494	fructose-1,6-bisphosphatase
BEP06_13330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BEP06_13335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BEP06_13340	COG0191	fructose-bisphosphate aldolase activity
BEP06_13345	COG2204	response regulator
BEP06_13350	COG4821	SIS domain
BEP06_13355	COG0504	CTP synthase activity
BEP06_13360	COG3343	RNA polymerase activity
BEP06_13365	COG1960	acyl-CoA dehydrogenase activity
BEP06_13370	COG2181	nitrate reductase activity
BEP06_13370	COG0247	lactate metabolic process
BEP06_13375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEP06_13380	COG4294	response to UV
BEP06_13390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BEP06_13395	COG1132	(ABC) transporter
BEP06_13400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEP06_13405	COG2181	nitrate reductase activity
BEP06_13410	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BEP06_13415	COG1140	nitrate reductase beta subunit
BEP06_13420	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BEP06_13425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BEP06_13435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BEP06_13440	COG2223	nitrite transmembrane transporter activity
BEP06_13445	COG0018	arginyl-trna synthetase
BEP06_13450	COG4506	Protein conserved in bacteria
BEP06_13455	COG3391	amine dehydrogenase activity
BEP06_13460	COG3391	amine dehydrogenase activity
BEP06_13470	COG0457	Tetratricopeptide repeat
BEP06_13480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BEP06_13485	COG0010	Belongs to the arginase family
BEP06_13490	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BEP06_13495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEP06_13505	COG1994	Peptidase M50
BEP06_13510	COG1942	4-Oxalocrotonate Tautomerase
BEP06_13515	COG1846	Transcriptional regulator
BEP06_13520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BEP06_13530	COG0477	Major facilitator Superfamily
BEP06_13535	COG1959	2 iron, 2 sulfur cluster binding
BEP06_13540	COG3465	dGTPase activity
BEP06_13545	COG1078	dGTPase activity
BEP06_13550	COG4844	belongs to the
BEP06_13560	COG0697	spore germination
BEP06_13565	COG0095	Lipoate-protein ligase
BEP06_13570	COG0583	DNA-binding transcription factor activity
BEP06_13575	COG0280	phosphate acetyltransferase
BEP06_13585	COG2814	Major facilitator Superfamily
BEP06_13590	COG0833	amino acid
BEP06_13595	COG4187	Peptidase family M20/M25/M40
BEP06_13600	COG1012	belongs to the aldehyde dehydrogenase family
BEP06_13605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BEP06_13610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BEP06_13615	COG1216	Glycosyl transferase, family 2
BEP06_13630	COG1695	Transcriptional regulator
BEP06_13635	COG0351	phosphomethylpyrimidine kinase
BEP06_13645	COG1621	beta-fructofuranosidase activity
BEP06_13650	COG1263	PTS System
BEP06_13650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_13655	COG2116	formate transmembrane transporter activity
BEP06_13660	COG3711	transcriptional antiterminator
BEP06_13670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEP06_13675	COG0778	Nitroreductase
BEP06_13680	COG0772	Belongs to the SEDS family
BEP06_13690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BEP06_13695	COG1845	cytochrome c oxidase, subunit III
BEP06_13700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BEP06_13705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BEP06_13710	COG2261	transglycosylase associated protein
BEP06_13715	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BEP06_13720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BEP06_13725	COG2246	polysaccharide biosynthetic process
BEP06_13730	COG1309	transcriptional regulator
BEP06_13740	COG3162	membrane
BEP06_13745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEP06_13750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BEP06_13755	COG2837	iron assimilation
BEP06_13760	COG2822	iron ion transport
BEP06_13765	COG0672	)-iron permease
BEP06_13770	COG0352	thiamine-phosphate diphosphorylase activity
BEP06_13775	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BEP06_13780	COG0583	DNA-binding transcription factor activity
BEP06_13785	COG1380	Effector of murein hydrolase LrgA
BEP06_13790	COG1346	cytolysis
BEP06_13795	COG2814	Major facilitator Superfamily
BEP06_13800	COG4895	conserved protein (DUF2196)
BEP06_13805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BEP06_13810	COG0346	lactoylglutathione lyase activity
BEP06_13815	COG1263	PTS System
BEP06_13815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_13820	COG3711	transcriptional antiterminator
BEP06_13825	COG1442	glycosyl transferase family 8
BEP06_13830	COG5522	Integral membrane protein (intg_mem_TP0381)
BEP06_13835	COG1846	Transcriptional regulator
BEP06_13840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BEP06_13845	COG2234	aminopeptidase activity
BEP06_13850	COG2357	RelA SpoT domain protein
BEP06_13855	COG1575	Belongs to the MenA family. Type 1 subfamily
BEP06_13870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BEP06_13875	COG1696	Membrane protein involved in D-alanine export
BEP06_13880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BEP06_13885	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BEP06_13890	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BEP06_13895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BEP06_13900	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BEP06_13905	COG4988	ABC transporter
BEP06_13910	COG1294	oxidase, subunit
BEP06_13915	COG1271	oxidase subunit
BEP06_13925	COG3209	COG3209 Rhs family protein
BEP06_13930	COG0697	spore germination
BEP06_13935	COG0589	response to stress
BEP06_13940	COG2723	6-phospho-beta-galactosidase activity
BEP06_13945	COG2190	(PTS) system
BEP06_13945	COG1263	PTS System
BEP06_13945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEP06_13960	COG5444	nuclease activity
BEP06_13975	COG3507	Belongs to the glycosyl hydrolase 43 family
BEP06_13990	COG2986	histidine ammonia-lyase
BEP06_13995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BEP06_14000	COG1228	amidohydrolase
BEP06_14005	COG0010	Belongs to the arginase family
BEP06_14010	COG0833	amino acid
BEP06_14015	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BEP06_14020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BEP06_14025	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BEP06_14030	COG2390	Transcriptional regulator
BEP06_14035	COG2814	Major facilitator Superfamily
BEP06_14040	COG0326	Molecular chaperone. Has ATPase activity
BEP06_14050	COG1028	Short-chain dehydrogenase reductase Sdr
BEP06_14055	COG1309	transcriptional regulator
BEP06_14060	COG1012	belongs to the aldehyde dehydrogenase family
BEP06_14065	COG0456	acetyltransferase
BEP06_14070	COG2850	peptidyl-arginine hydroxylation
BEP06_14075	COG2226	methyltransferase
BEP06_14090	COG0367	asparagine synthase
BEP06_14095	COG1929	Belongs to the glycerate kinase type-1 family
BEP06_14100	COG1802	Transcriptional regulator
BEP06_14105	COG1070	Carbohydrate kinase
BEP06_14110	COG2610	gluconate transmembrane transporter activity
BEP06_14115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BEP06_14120	COG0450	alkyl hydroperoxide reductase
BEP06_14125	COG3634	alkyl hydroperoxide reductase activity
BEP06_14130	COG2723	6-phospho-beta-galactosidase activity
BEP06_14135	COG2190	(PTS) system
BEP06_14140	COG2188	Transcriptional regulator
BEP06_14155	COG1131	(ABC) transporter
BEP06_14160	COG1994	Peptidase M50
BEP06_14165	COG0535	radical SAM domain protein
BEP06_14175	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BEP06_14180	COG0010	Belongs to the arginase family
BEP06_14185	COG0833	amino acid
BEP06_14190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BEP06_14195	COG3829	transcription factor binding
BEP06_14200	COG5002	protein histidine kinase activity
BEP06_14210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEP06_14215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BEP06_14220	COG4853	Protein conserved in bacteria
BEP06_14225	COG4863	YycH protein
BEP06_14230	COG5002	protein histidine kinase activity
BEP06_14235	COG0745	RESPONSE REGULATOR receiver
BEP06_14265	COG0346	lactoylglutathione lyase activity
BEP06_14270	COG0305	Participates in initiation and elongation during chromosome replication
BEP06_14290	COG3093	addiction module antidote protein HigA
BEP06_14295	COG2807	transmembrane transport
BEP06_14300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BEP06_14305	COG0359	binds to the 23S rRNA
BEP06_14310	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BEP06_14315	COG4241	membrane
BEP06_14325	COG5577	PFAM Coat F domain
BEP06_14330	COG1733	regulation of RNA biosynthetic process
BEP06_14335	COG1227	inorganic diphosphatase activity
BEP06_14340	COG0110	maltose O-acetyltransferase activity
BEP06_14345	COG0346	lactoylglutathione lyase activity
BEP06_14350	COG1609	Transcriptional regulator
BEP06_14355	COG0708	Exodeoxyribonuclease III
BEP06_14360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BEP06_14365	COG0629	single-stranded DNA binding
BEP06_14370	COG0360	Binds together with S18 to 16S ribosomal RNA
BEP06_14375	COG0012	GTP binding
BEP06_14380	COG0243	molybdopterin cofactor binding
BEP06_14385	COG4481	Protein conserved in bacteria
BEP06_14390	COG3949	Membrane
BEP06_14400	COG1475	DNA binding
BEP06_14405	COG1192	Involved in chromosome partitioning
BEP06_14415	COG1475	DNA binding
BEP06_14420	COG0357	Ribosomal RNA small subunit methyltransferase G
BEP06_14425	COG0445	tRNA wobble uridine modification
BEP06_14430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BEP06_14435	COG1847	R3H domain protein
BEP06_14440	COG0706	membrane insertase activity
BEP06_14445	COG0594	ribonuclease P activity
BEP06_14450	COG0230	Belongs to the bacterial ribosomal protein bL34 family