locus-tag	class	description
D9C11_00010	COG1876	peptidase activity
D9C11_00015	COG0813	purine-nucleoside phosphorylase activity
D9C11_00030	COG0671	phosphoesterase, PA-phosphatase related
D9C11_00055	COG4479	Belongs to the UPF0346 family
D9C11_00100	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_00100	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_00115	COG0457	Tetratricopeptide repeat
D9C11_00125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C11_00160	COG3344	reverse transcriptase
D9C11_00165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_00180	COG5444	nuclease activity
D9C11_00190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C11_00195	COG1086	Polysaccharide biosynthesis protein
D9C11_00200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C11_00205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9C11_00210	COG1846	Transcriptional regulator
D9C11_00215	COG0534	Mate efflux family protein
D9C11_00225	COG4698	Protein conserved in bacteria
D9C11_00230	COG2755	lipolytic protein G-D-S-L family
D9C11_00235	COG1999	signal sequence binding
D9C11_00245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9C11_00250	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C11_00255	COG1272	protein, Hemolysin III
D9C11_00260	COG0204	Acyl-transferase
D9C11_00265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C11_00270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C11_00280	COG2136	Putative SAM-dependent methyltransferase
D9C11_00280	COG2521	methyltransferase
D9C11_00290	COG0129	dihydroxy-acid dehydratase activity
D9C11_00295	COG1413	lyase activity
D9C11_00300	COG1418	mRNA catabolic process
D9C11_00305	COG0386	Belongs to the glutathione peroxidase family
D9C11_00310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9C11_00315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C11_00325	COG1278	Cold shock
D9C11_00345	COG0328	RNA-DNA hybrid ribonuclease activity
D9C11_00350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9C11_00355	COG0328	RNA-DNA hybrid ribonuclease activity
D9C11_00365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C11_00390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C11_00400	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9C11_00460	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_00560	COG0740	serine-type endopeptidase activity
D9C11_00640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C11_00645	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9C11_00655	COG0800	Aldolase
D9C11_00660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C11_00665	COG1609	Transcriptional regulator
D9C11_00670	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9C11_00675	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_00680	COG1199	ATP-dependent helicase activity
D9C11_00695	COG0116	Belongs to the methyltransferase superfamily
D9C11_00710	COG4474	Belongs to the UPF0398 family
D9C11_00725	COG3359	exonuclease
D9C11_00730	COG1111	helicase
D9C11_00730	COG1205	dead DEAH box helicase
D9C11_00735	COG2190	(PTS) system
D9C11_00740	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C11_00775	COG3331	DNA recombination
D9C11_00780	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C11_00780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C11_00790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9C11_00795	COG3935	DnaD domain protein
D9C11_00800	COG0017	Asparaginyl-tRNA synthetase
D9C11_00805	COG0436	Aminotransferase
D9C11_00810	COG5353	protein conserved in bacteria
D9C11_00820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9C11_00820	COG1199	ATP-dependent helicase activity
D9C11_00825	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9C11_00830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9C11_00835	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9C11_00840	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D9C11_00840	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D9C11_00845	COG0617	tRNA 3'-terminal CCA addition
D9C11_00850	COG0438	transferase activity, transferring glycosyl groups
D9C11_00855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C11_00860	COG1803	Methylglyoxal synthase
D9C11_00865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9C11_00870	COG1694	Mazg nucleotide pyrophosphohydrolase
D9C11_00875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C11_00885	COG4347	Protein of unknown function (DUF1405)
D9C11_00890	COG2010	Cytochrome c
D9C11_00890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C11_00895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9C11_00900	COG0723	plastoquinol--plastocyanin reductase activity
D9C11_00910	COG5582	Belongs to the UPF0302 family
D9C11_00915	COG0457	Tetratricopeptide repeat
D9C11_00920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9C11_00925	COG0287	Prephenate dehydrogenase
D9C11_00935	COG0159	tryptophan synthase activity
D9C11_00940	COG0133	tryptophan synthase activity
D9C11_00945	COG0135	phosphoribosylanthranilate isomerase activity
D9C11_00955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9C11_00960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C11_00965	COG4401	Chorismate mutase type I
D9C11_00970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9C11_00975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9C11_00980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9C11_00985	COG0105	UTP biosynthetic process
D9C11_00990	COG0142	geranyltranstransferase activity
D9C11_00995	COG2226	methyltransferase
D9C11_01000	COG0142	geranyltranstransferase activity
D9C11_01010	COG0302	gtp cyclohydrolase
D9C11_01015	COG0776	regulation of translation
D9C11_01020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9C11_01035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9C11_01040	COG1160	GTP binding
D9C11_01070	COG1304	FMN binding
D9C11_01075	COG0539	negative regulation of cytoplasmic translation
D9C11_01080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9C11_01090	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9C11_01095	COG2959	enzyme of heme biosynthesis
D9C11_01100	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_01100	COG3773	Cell wall hydrolase
D9C11_01105	COG2339	peptidase activity
D9C11_01110	COG0492	ferredoxin-NADP+ reductase activity
D9C11_01115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C11_01120	COG4862	establishment of competence for transformation
D9C11_01125	COG1408	metallophosphoesterase
D9C11_01135	COG1388	LysM domain
D9C11_01140	COG1266	CAAX protease self-immunity
D9C11_01145	COG0514	ATP-dependent DNA helicase (RecQ)
D9C11_01150	COG4955	Helix-turn-helix domain
D9C11_01155	COG1141	Ferredoxin
D9C11_01160	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9C11_01165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9C11_01175	COG0710	3-dehydroquinate dehydratase activity
D9C11_01185	COG1595	DNA-templated transcription, initiation
D9C11_01190	COG5002	protein histidine kinase activity
D9C11_01195	COG0745	RESPONSE REGULATOR receiver
D9C11_01200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C11_01205	COG1333	cytochrome c biogenesis protein
D9C11_01210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_01215	COG1187	pseudouridine synthase activity
D9C11_01220	COG0700	Nucleoside recognition
D9C11_01225	COG2715	membrane protein required for spore maturation
D9C11_01230	COG1686	Belongs to the peptidase S11 family
D9C11_01240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9C11_01245	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9C11_01250	COG1547	Domain of unknown function (DUF309)
D9C11_01255	COG0456	acetyltransferase
D9C11_01260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9C11_01265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C11_01265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9C11_01270	COG0307	riboflavin synthase, alpha
D9C11_01275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C11_01275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9C11_01285	COG0681	Belongs to the peptidase S26 family
D9C11_01295	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9C11_01325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9C11_01335	COG4086	secreted protein
D9C11_01350	COG0019	diaminopimelate decarboxylase activity
D9C11_01355	COG0697	spore germination
D9C11_01370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C11_01390	COG1191	sigma factor activity
D9C11_01395	COG2172	sigma factor antagonist activity
D9C11_01400	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C11_01405	COG1686	Belongs to the peptidase S11 family
D9C11_01410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9C11_01415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9C11_01420	COG4974	Belongs to the 'phage' integrase family
D9C11_01430	COG0735	belongs to the Fur family
D9C11_01435	COG1300	Membrane
D9C11_01445	COG0281	malic enzyme
D9C11_01450	COG1757	Na H antiporter
D9C11_01455	COG1027	Aspartate ammonia-lyase
D9C11_01460	COG0252	asparaginase activity
D9C11_01465	COG1396	sequence-specific DNA binding
D9C11_01470	COG1379	DNA repair
D9C11_01475	COG0494	nUDIX hydrolase
D9C11_01485	COG0667	Aldo Keto reductase
D9C11_01495	COG3328	transposase activity
D9C11_01505	COG1073	alpha beta
D9C11_01515	COG4918	Iron-sulphur cluster biosynthesis
D9C11_01520	COG0456	acetyltransferase
D9C11_01520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9C11_01525	COG2329	Antibiotic biosynthesis monooxygenase
D9C11_01530	COG0456	acetyltransferase
D9C11_01540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C11_01560	COG1072	(Pantothenic acid kinase))
D9C11_01570	COG0300	oxidoreductase activity
D9C11_01575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C11_01580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C11_01585	COG4187	Peptidase family M20/M25/M40
D9C11_01590	COG1902	pentaerythritol trinitrate reductase activity
D9C11_01595	COG0596	Alpha beta hydrolase
D9C11_01605	COG1234	tRNA 3'-trailer cleavage
D9C11_01610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9C11_01615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C11_01620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9C11_01630	COG0706	membrane insertase activity
D9C11_01635	COG3361	conserved protein (COG2071)
D9C11_01645	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C11_01655	COG0346	lactoylglutathione lyase activity
D9C11_01660	COG1376	ErfK ybiS ycfS ynhG family protein
D9C11_01665	COG4129	membrane
D9C11_01670	COG1126	abc transporter atp-binding protein
D9C11_01675	COG0765	amino acid transport
D9C11_01680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C11_01690	COG1597	lipid kinase activity
D9C11_01700	COG4978	Transcriptional regulator
D9C11_01700	COG0789	Transcriptional regulator
D9C11_01705	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C11_01710	COG0022	dehydrogenase e1 component
D9C11_01715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C11_01720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C11_01725	COG3426	butyrate kinase activity
D9C11_01730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C11_01735	COG0280	phosphate acetyltransferase
D9C11_01740	COG3829	transcription factor binding
D9C11_01740	COG3290	protein histidine kinase activity
D9C11_01750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9C11_01755	COG2079	MmgE PrpD family protein
D9C11_01760	COG0372	Belongs to the citrate synthase family
D9C11_01765	COG1960	acyl-CoA dehydrogenase activity
D9C11_01770	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C11_01780	COG0584	glycerophosphoryl diester phosphodiesterase
D9C11_01785	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_01800	COG1902	pentaerythritol trinitrate reductase activity
D9C11_01805	COG0745	RESPONSE REGULATOR receiver
D9C11_01815	COG0750	zinc metalloprotease
D9C11_01820	COG0497	DNA recombination
D9C11_01825	COG1438	arginine binding
D9C11_01830	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9C11_01835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9C11_01840	COG0142	geranyltranstransferase activity
D9C11_01845	COG1722	exodeoxyribonuclease VII activity
D9C11_01850	COG1570	exodeoxyribonuclease VII activity
D9C11_01855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9C11_01860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C11_01865	COG1302	Protein conserved in bacteria
D9C11_01870	COG0439	Biotin carboxylase
D9C11_01875	COG0511	ligase activity, forming carbon-carbon bonds
D9C11_01915	COG3854	ATPases associated with a variety of cellular activities
D9C11_01925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9C11_01930	COG0006	proline dipeptidase activity
D9C11_01935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9C11_01945	COG3872	metal-dependent enzyme
D9C11_01955	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C11_01960	COG1321	iron dependent repressor
D9C11_01965	COG0095	Lipoate-protein ligase
D9C11_01970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C11_01975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C11_01980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9C11_01985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9C11_01990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C11_02005	COG1396	sequence-specific DNA binding
D9C11_02015	COG0681	Belongs to the peptidase S26 family
D9C11_02050	COG4940	Competence protein ComGF
D9C11_02060	COG4970	Tfp pilus assembly protein FimT
D9C11_02065	COG4537	Required for transformation and DNA binding
D9C11_02070	COG1459	type II secretion system
D9C11_02075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9C11_02090	COG1253	flavin adenine dinucleotide binding
D9C11_02095	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C11_02105	COG1393	Belongs to the ArsC family
D9C11_02115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C11_02125	COG0011	TIGRFAM Protein of
D9C11_02135	COG2866	Carboxypeptidase
D9C11_02140	COG1368	sulfuric ester hydrolase activity
D9C11_02150	COG4483	Protein conserved in bacteria
D9C11_02155	COG0705	Rhomboid family
D9C11_02155	COG0457	Tetratricopeptide repeat
D9C11_02165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9C11_02170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C11_02175	COG0438	transferase activity, transferring glycosyl groups
D9C11_02190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C11_02195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C11_02200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C11_02205	COG0581	inorganic phosphate transmembrane transporter activity
D9C11_02210	COG0573	inorganic phosphate transmembrane transporter activity
D9C11_02215	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9C11_02225	COG0477	Major facilitator Superfamily
D9C11_02230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C11_02235	COG2839	Protein conserved in bacteria
D9C11_02240	COG5521	maltodextrose utilization protein MalA
D9C11_02245	COG1388	LysM domain
D9C11_02250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9C11_02255	COG4709	membrane
D9C11_02260	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9C11_02265	COG0735	belongs to the Fur family
D9C11_02270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C11_02280	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9C11_02285	COG0513	Belongs to the DEAD box helicase family
D9C11_02295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9C11_02300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9C11_02305	COG2384	SAM-dependent methyltransferase
D9C11_02310	COG2010	Cytochrome c
D9C11_02320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9C11_02325	COG0358	DNA primase activity
D9C11_02330	COG1671	Belongs to the UPF0178 family
D9C11_02335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9C11_02340	COG0517	IMP dehydrogenase activity
D9C11_02345	COG0751	glycine-tRNA ligase activity
D9C11_02350	COG0752	glycyl-tRNA synthetase alpha subunit
D9C11_02355	COG1381	Involved in DNA repair and RecF pathway recombination
D9C11_02365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9C11_02370	COG0295	cytidine deaminase activity
D9C11_02375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9C11_02380	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9C11_02385	COG1480	7TM receptor with intracellular HD hydrolase
D9C11_02390	COG1702	phosphate starvation-inducible protein PhoH
D9C11_02395	COG0561	phosphatase activity
D9C11_02410	COG4864	UPF0365 protein
D9C11_02415	COG1030	water channel activity
D9C11_02420	COG1610	YqeY-like protein
D9C11_02425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9C11_02430	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9C11_02440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C11_02445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9C11_02450	COG2264	protein methyltransferase activity
D9C11_02455	COG0484	heat shock protein binding
D9C11_02460	COG0443	Heat shock 70 kDa protein
D9C11_02465	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9C11_02470	COG1420	regulation of RNA biosynthetic process
D9C11_02475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C11_02480	COG0481	GTPase activity
D9C11_02490	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_02495	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9C11_02500	COG0268	Binds directly to 16S ribosomal RNA
D9C11_02505	COG1466	dna polymerase III delta subunit
D9C11_02525	COG2131	deaminase
D9C11_02530	COG1596	polysaccharide export
D9C11_02530	COG1555	photosystem II stabilization
D9C11_02535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C11_02540	COG2226	methyltransferase
D9C11_02545	COG0799	negative regulation of ribosome biogenesis
D9C11_02550	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9C11_02555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9C11_02560	COG1534	Rna-binding protein
D9C11_02565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9C11_02570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C11_02575	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9C11_02585	COG2755	lipolytic protein G-D-S-L family
D9C11_02590	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_02590	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_02595	COG0398	Pfam SNARE associated Golgi protein
D9C11_02600	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
D9C11_02610	COG3209	COG3209 Rhs family protein
D9C11_02625	COG3328	transposase activity
D9C11_02635	COG0425	Belongs to the sulfur carrier protein TusA family
D9C11_02640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C11_02640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C11_02650	COG0425	Belongs to the sulfur carrier protein TusA family
D9C11_02650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C11_02660	COG2210	Belongs to the sulfur carrier protein TusA family
D9C11_02665	COG1937	Protein conserved in bacteria
D9C11_02680	COG0662	Cupin 2, conserved barrel domain protein
D9C11_02695	COG0789	Transcriptional regulator
D9C11_02695	COG4978	Transcriptional regulator
D9C11_02700	COG2814	Major facilitator Superfamily
D9C11_02705	COG0456	acetyltransferase
D9C11_02720	COG0697	spore germination
D9C11_02755	COG2072	flavoprotein involved in K transport
D9C11_02760	COG1230	cation diffusion facilitator family transporter
D9C11_02770	COG1114	Component of the transport system for branched-chain amino acids
D9C11_02775	COG1687	branched-chain amino acid
D9C11_02785	COG1522	sequence-specific DNA binding
D9C11_02790	COG2732	(Barnase) inhibitor
D9C11_02795	COG2124	cytochrome p450
D9C11_02820	COG5577	PFAM Coat F domain
D9C11_02830	COG0789	Transcriptional regulator
D9C11_02840	COG1064	alcohol dehydrogenase
D9C11_02845	COG0693	protein deglycase activity
D9C11_02850	COG1621	beta-fructofuranosidase activity
D9C11_02855	COG3716	PTS system mannose fructose sorbose family IID component
D9C11_02860	COG3715	PTS system
D9C11_02865	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_02870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C11_02875	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9C11_02875	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D9C11_02885	COG1113	amino acid transport
D9C11_02890	COG1280	lysine exporter protein (LysE YggA)
D9C11_02895	COG1378	Sugar-specific transcriptional regulator TrmB
D9C11_02925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C11_02925	COG2124	cytochrome p450
D9C11_02930	COG1309	transcriptional regulator
D9C11_02935	COG2226	methyltransferase
D9C11_02950	COG2116	formate transmembrane transporter activity
D9C11_02955	COG5609	conserved protein (DUF2294)
D9C11_02960	COG3383	formate dehydrogenase (NAD+) activity
D9C11_02965	COG2427	Protein of unknown function (DUF1641)
D9C11_02975	COG0626	cystathionine gamma-synthase activity
D9C11_02980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C11_02985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9C11_02990	COG2226	methyltransferase
D9C11_03005	COG0768	penicillin binding
D9C11_03010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9C11_03015	COG0572	uridine kinase
D9C11_03035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9C11_03040	COG3906	Belongs to the UPF0473 family
D9C11_03045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9C11_03050	COG4472	Bacterial protein of unknown function (DUF965)
D9C11_03055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9C11_03060	COG0628	permease
D9C11_03065	COG1126	abc transporter atp-binding protein
D9C11_03070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C11_03075	COG0765	amino acid transport
D9C11_03080	COG0765	amino acid transport
D9C11_03095	COG3881	PFAM PRC-barrel domain
D9C11_03100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9C11_03105	COG0457	Tetratricopeptide repeat
D9C11_03110	COG0482	sulfurtransferase activity
D9C11_03115	COG1104	cysteine desulfurase activity
D9C11_03120	COG1959	2 iron, 2 sulfur cluster binding
D9C11_03125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9C11_03135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9C11_03145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9C11_03150	COG0124	histidyl-tRNA synthetase
D9C11_03160	COG3103	Sh3 type 3 domain protein
D9C11_03160	COG4991	sh3 domain protein
D9C11_03160	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_03165	COG1490	D-aminoacyl-tRNA deacylase activity
D9C11_03170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9C11_03175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C11_03180	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9C11_03180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9C11_03185	COG5416	Lipopolysaccharide assembly protein A domain
D9C11_03190	COG0490	domain, Protein
D9C11_03195	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C11_03195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9C11_03205	COG2244	polysaccharide biosynthetic process
D9C11_03210	COG2323	membrane
D9C11_03225	COG1862	Preprotein translocase
D9C11_03230	COG0343	queuine tRNA-ribosyltransferase activity
D9C11_03235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9C11_03245	COG2255	four-way junction helicase activity
D9C11_03250	COG0632	four-way junction helicase activity
D9C11_03260	COG2814	Major facilitator Superfamily
D9C11_03265	COG0673	inositol 2-dehydrogenase activity
D9C11_03290	COG1115	amino acid carrier protein
D9C11_03295	COG0217	transcriptional regulatory protein
D9C11_03305	COG1388	LysM domain
D9C11_03310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9C11_03315	COG0157	Belongs to the NadC ModD family
D9C11_03320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9C11_03325	COG1104	cysteine desulfurase activity
D9C11_03330	COG1827	regulation of RNA biosynthetic process
D9C11_03335	COG0077	Prephenate dehydratase
D9C11_03340	COG4492	Belongs to the UPF0735 family
D9C11_03345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9C11_03350	COG3290	protein histidine kinase activity
D9C11_03360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9C11_03365	COG2868	ribosomal protein
D9C11_03370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9C11_03375	COG1994	Peptidase M50
D9C11_03380	COG0739	heme binding
D9C11_03385	COG2894	cell division
D9C11_03390	COG0850	regulation of cytokinetic process
D9C11_03395	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9C11_03400	COG1792	Involved in formation and maintenance of cell shape
D9C11_03405	COG1077	Cell shape determining protein MreB Mrl
D9C11_03435	COG5444	nuclease activity
D9C11_03445	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_03445	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_03450	COG4824	toxin secretion phage lysis holin
D9C11_03480	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C11_03490	COG5280	Phage tail tape measure protein TP901
D9C11_03490	COG3953	SLT domain
D9C11_03580	COG4980	gas vesicle protein
D9C11_03580	COG1674	ftsk spoiiie
D9C11_03620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C11_03620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C11_03660	COG1396	sequence-specific DNA binding
D9C11_03675	COG2003	Belongs to the UPF0758 family
D9C11_03680	COG0424	maF-like protein
D9C11_03690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9C11_03695	COG0285	dihydrofolate synthase activity
D9C11_03700	COG0525	valine-tRNA ligase activity
D9C11_03710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C11_03715	COG1388	LysM domain
D9C11_03720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C11_03725	COG0113	porphobilinogen synthase activity
D9C11_03730	COG1587	Uroporphyrinogen-III synthase
D9C11_03735	COG0181	hydroxymethylbilane synthase activity
D9C11_03740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9C11_03745	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9C11_03755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9C11_03760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9C11_03765	COG0470	DNA polymerase III
D9C11_03765	COG1067	ATP-dependent peptidase activity
D9C11_03770	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9C11_03775	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9C11_03780	COG1477	protein flavinylation
D9C11_03780	COG0457	Tetratricopeptide repeat
D9C11_03785	COG0066	3-isopropylmalate dehydratase activity
D9C11_03790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9C11_03795	COG0473	3-isopropylmalate dehydrogenase activity
D9C11_03800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C11_03805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9C11_03810	COG0440	acetolactate synthase activity
D9C11_03815	COG0028	Belongs to the TPP enzyme family
D9C11_03825	COG0454	-acetyltransferase
D9C11_03840	COG0622	Phosphoesterase
D9C11_03845	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9C11_03850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9C11_03855	COG5401	PFAM Sporulation and spore germination
D9C11_03860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9C11_03870	COG2197	response regulator
D9C11_03875	COG0824	Thioesterase
D9C11_03880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9C11_03885	COG1053	succinate dehydrogenase
D9C11_03890	COG2009	succinate dehydrogenase
D9C11_03895	COG1719	4-vinyl reductase, 4VR
D9C11_03900	COG0527	aspartate kinase activity
D9C11_03910	COG0322	excinuclease ABC activity
D9C11_03915	COG3118	belongs to the thioredoxin family
D9C11_03920	COG3534	alpha-L-arabinofuranosidase
D9C11_03925	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9C11_03930	COG2086	electron transfer activity
D9C11_03935	COG1024	Enoyl-CoA hydratase
D9C11_03940	COG1309	transcriptional regulator
D9C11_03950	COG3766	membrane
D9C11_03955	COG1193	negative regulation of DNA recombination
D9C11_03960	COG1796	DNA polymerase
D9C11_03960	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C11_03965	COG1286	toxin biosynthetic process
D9C11_03970	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9C11_03975	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C11_03980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C11_03980	COG0072	phenylalanine-tRNA ligase activity
D9C11_03985	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9C11_03995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C11_04005	COG3835	regulator
D9C11_04010	COG0277	FAD linked oxidase domain protein
D9C11_04015	COG0247	lactate metabolic process
D9C11_04020	COG0346	lactoylglutathione lyase activity
D9C11_04025	COG1966	Carbon starvation protein
D9C11_04030	COG3534	alpha-L-arabinofuranosidase
D9C11_04035	COG0395	ABC-type sugar transport system, permease component
D9C11_04040	COG1175	transmembrane transport
D9C11_04045	COG1653	transport
D9C11_04050	COG0371	Dehydrogenase
D9C11_04055	COG0647	UMP catabolic process
D9C11_04060	COG0235	Class ii aldolase
D9C11_04065	COG1069	ribulokinase activity
D9C11_04070	COG2160	L-arabinose isomerase activity
D9C11_04075	COG3507	Belongs to the glycosyl hydrolase 43 family
D9C11_04080	COG1363	Peptidase, m42
D9C11_04090	COG3326	Membrane
D9C11_04095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9C11_04100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9C11_04105	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9C11_04115	COG1346	cytolysis
D9C11_04120	COG1380	Effector of murein hydrolase LrgA
D9C11_04125	COG3279	Response regulator of the LytR AlgR family
D9C11_04130	COG3275	phosphorelay sensor kinase activity
D9C11_04140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C11_04150	COG0398	Pfam SNARE associated Golgi protein
D9C11_04155	COG1484	DNA-dependent DNA replication
D9C11_04160	COG3611	Membrane attachment protein
D9C11_04165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9C11_04170	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9C11_04175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C11_04200	COG0237	dephospho-CoA kinase activity
D9C11_04205	COG1971	Probably functions as a manganese efflux pump
D9C11_04210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9C11_04215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C11_04215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9C11_04220	COG5002	protein histidine kinase activity
D9C11_04225	COG0745	RESPONSE REGULATOR receiver
D9C11_04230	COG0039	L-malate dehydrogenase activity
D9C11_04235	COG0538	isocitrate dehydrogenase activity
D9C11_04240	COG0372	Belongs to the citrate synthase family
D9C11_04245	COG2707	UPF0756 membrane protein
D9C11_04250	COG0628	permease
D9C11_04255	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9C11_04260	COG0469	pyruvate kinase activity
D9C11_04265	COG0205	6-phosphofructokinase activity
D9C11_04270	COG0825	malonyl-CoA metabolic process
D9C11_04275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9C11_04280	COG0281	malic enzyme
D9C11_04285	COG0587	DNA-directed DNA polymerase activity
D9C11_04305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9C11_04315	COG4109	DRTGG domain
D9C11_04320	COG0730	response to heat
D9C11_04325	COG1473	amidohydrolase
D9C11_04330	COG0196	riboflavin kinase activity
D9C11_04340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D9C11_04345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C11_04350	COG1126	abc transporter atp-binding protein
D9C11_04355	COG0765	amino acid transport
D9C11_04360	COG0765	amino acid transport
D9C11_04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C11_04370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C11_04375	COG0454	-acetyltransferase
D9C11_04380	COG0583	DNA-binding transcription factor activity
D9C11_04385	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9C11_04390	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_04400	COG0165	Argininosuccinate lyase
D9C11_04405	COG0137	argininosuccinate synthase activity
D9C11_04410	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9C11_04415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9C11_04425	COG0827	DNA restriction-modification system
D9C11_04430	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9C11_04435	COG3874	Sporulation protein YtfJ
D9C11_04445	COG1714	RDD family
D9C11_04450	COG0616	signal peptide processing
D9C11_04455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C11_04460	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9C11_04465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C11_04475	COG0301	tRNA thio-modification
D9C11_04480	COG1104	cysteine desulfurase activity
D9C11_04485	COG1114	Component of the transport system for branched-chain amino acids
D9C11_04490	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9C11_04495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9C11_04500	COG1309	transcriptional regulator
D9C11_04505	COG1956	GAF domain-containing protein
D9C11_04515	COG2203	Gaf domain
D9C11_04515	COG2199	diguanylate cyclase activity
D9C11_04525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9C11_04530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C11_04535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9C11_04540	COG0454	-acetyltransferase
D9C11_04545	COG0517	IMP dehydrogenase activity
D9C11_04550	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9C11_04555	COG1360	Flagellar Motor Protein
D9C11_04560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C11_04565	COG1609	Transcriptional regulator
D9C11_04570	COG1605	Chorismate mutase
D9C11_04570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9C11_04575	COG3118	belongs to the thioredoxin family
D9C11_04580	COG4980	gas vesicle protein
D9C11_04585	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C11_04590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9C11_04595	COG1674	ftsk spoiiie
D9C11_04600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C11_04605	COG4848	Belongs to the UPF0354 family
D9C11_04610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_04625	COG1363	Peptidase, m42
D9C11_04630	COG5584	Small secreted protein
D9C11_04635	COG0281	malic enzyme
D9C11_04640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C11_04645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9C11_04655	COG0510	thiamine kinase activity
D9C11_04660	COG1523	belongs to the glycosyl hydrolase 13 family
D9C11_04665	COG1597	lipid kinase activity
D9C11_04675	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C11_04680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C11_04685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C11_04690	COG2252	PERMEase
D9C11_04700	COG1131	(ABC) transporter
D9C11_04705	COG1349	DNA-binding transcription factor activity
D9C11_04710	COG1187	pseudouridine synthase activity
D9C11_04715	COG2244	polysaccharide biosynthetic process
D9C11_04720	COG2081	HI0933 family
D9C11_04725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9C11_04745	COG1653	transport
D9C11_04750	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9C11_04755	COG4209	transmembrane transport
D9C11_04765	COG1653	transport
D9C11_04770	COG0395	ABC-type sugar transport system, permease component
D9C11_04775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C11_04780	COG2124	cytochrome p450
D9C11_04785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9C11_04800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C11_04810	COG1073	alpha beta
D9C11_04835	COG1486	melibiose metabolic process
D9C11_04840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9C11_04845	COG0495	leucyl-tRNA aminoacylation
D9C11_04860	COG2814	Major facilitator Superfamily
D9C11_04875	COG3328	transposase activity
D9C11_04890	COG1136	(ABC) transporter
D9C11_04895	COG2205	protein histidine kinase activity
D9C11_04900	COG0745	RESPONSE REGULATOR receiver
D9C11_04905	COG0577	efflux transmembrane transporter activity
D9C11_04910	COG1136	(ABC) transporter
D9C11_04925	COG1131	(ABC) transporter
D9C11_04930	COG1725	Transcriptional regulator
D9C11_04950	COG1242	4 iron, 4 sulfur cluster binding
D9C11_04955	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9C11_04965	COG2267	carboxylic ester hydrolase activity
D9C11_04970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9C11_04975	COG1113	amino acid transport
D9C11_04980	COG0367	asparagine synthase
D9C11_04985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9C11_04990	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9C11_05000	COG1506	peptidase
D9C11_05005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C11_05010	COG1116	anion transmembrane transporter activity
D9C11_05015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C11_05020	COG0494	nUDIX hydrolase
D9C11_05025	COG4824	toxin secretion phage lysis holin
D9C11_05030	COG0783	Belongs to the Dps family
D9C11_05045	COG1854	S-ribosylhomocysteine lyase activity
D9C11_05050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9C11_05055	COG0288	reversible hydration of carbon dioxide
D9C11_05060	COG0254	rRNA binding
D9C11_05065	COG1271	oxidase subunit
D9C11_05070	COG1294	oxidase, subunit
D9C11_05080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C11_05085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C11_05085	COG1321	iron dependent repressor
D9C11_05090	COG1121	(ABC) transporter
D9C11_05095	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C11_05100	COG4948	Mandelate Racemase Muconate Lactonizing
D9C11_05105	COG0318	PFAM AMP-dependent synthetase and ligase
D9C11_05110	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9C11_05115	COG0596	Alpha beta hydrolase
D9C11_05120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9C11_05125	COG1169	isochorismate synthase
D9C11_05135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C11_05140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C11_05145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C11_05150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C11_05155	COG0438	transferase activity, transferring glycosyl groups
D9C11_05165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C11_05170	COG0438	transferase activity, transferring glycosyl groups
D9C11_05175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C11_05180	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9C11_05195	COG0058	SHG alpha-glucan phosphorylase activity
D9C11_05200	COG0297	glycogen (starch) synthase activity
D9C11_05205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C11_05210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9C11_05215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9C11_05340	COG3859	Proton-coupled thiamine transporter YuaJ
D9C11_05345	COG1247	-acetyltransferase
D9C11_05350	COG2268	Band 7 protein
D9C11_05355	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9C11_05360	COG2318	DinB family
D9C11_05370	COG1454	alcohol dehydrogenase
D9C11_05380	COG1510	regulation of RNA biosynthetic process
D9C11_05395	COG0569	domain protein
D9C11_05400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C11_05405	COG4682	membrane
D9C11_05410	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9C11_05415	COG0477	Major facilitator Superfamily
D9C11_05420	COG5553	Cysteine dioxygenase type I
D9C11_05465	COG5444	nuclease activity
D9C11_05470	COG0457	Tetratricopeptide repeat
D9C11_05495	COG1968	undecaprenyl-diphosphatase activity
D9C11_05500	COG0628	permease
D9C11_05505	COG0673	inositol 2-dehydrogenase activity
D9C11_05510	COG4806	L-rhamnose isomerase
D9C11_05520	COG1070	Carbohydrate kinase
D9C11_05525	COG1349	DNA-binding transcription factor activity
D9C11_05530	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_05530	COG3347	Dehydrogenase
D9C11_05535	COG0840	transmembrane signaling receptor activity
D9C11_05540	COG0840	transmembrane signaling receptor activity
D9C11_05545	COG0840	transmembrane signaling receptor activity
D9C11_05550	COG0840	transmembrane signaling receptor activity
D9C11_05565	COG0432	Pfam Uncharacterised protein family UPF0047
D9C11_05575	COG0366	Alpha amylase catalytic
D9C11_05580	COG1253	flavin adenine dinucleotide binding
D9C11_05585	COG2738	Putative neutral zinc metallopeptidase
D9C11_05600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9C11_05615	COG0166	Belongs to the GPI family
D9C11_05620	COG1979	alcohol dehydrogenase
D9C11_05625	COG1979	alcohol dehydrogenase
D9C11_05630	COG2155	Conserved Protein
D9C11_05635	COG1098	S1 RNA binding domain
D9C11_05640	COG0436	Aminotransferase
D9C11_05645	COG1522	sequence-specific DNA binding
D9C11_05650	COG2267	carboxylic ester hydrolase activity
D9C11_05660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9C11_05665	COG2205	protein histidine kinase activity
D9C11_05675	COG5018	Exonuclease
D9C11_05685	COG2814	Major facilitator Superfamily
D9C11_05690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C11_05695	COG3011	Protein conserved in bacteria
D9C11_05705	COG3290	protein histidine kinase activity
D9C11_05710	COG4565	transcriptional regulatory protein
D9C11_05735	COG3493	citrate carrier protein
D9C11_05745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C11_05745	COG2111	Na H antiporter
D9C11_05750	COG2111	Na H antiporter
D9C11_05755	COG1006	Multisubunit Na H antiporter MnhC subunit
D9C11_05760	COG0651	ATP synthesis coupled electron transport
D9C11_05765	COG1863	multisubunit Na H antiporter MnhE subunit
D9C11_05770	COG2212	antiporter activity
D9C11_05775	COG1320	monovalent cation:proton antiporter activity
D9C11_05780	COG2050	protein possibly involved in aromatic compounds catabolism
D9C11_05785	COG2197	response regulator
D9C11_05790	COG4585	Histidine kinase
D9C11_05800	COG0142	geranyltranstransferase activity
D9C11_05820	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9C11_05825	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9C11_05830	COG1335	isochorismatase
D9C11_05835	COG5506	Protein of unknown function (DUF1694)
D9C11_05850	COG0628	permease
D9C11_05865	COG1418	mRNA catabolic process
D9C11_05870	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_05880	COG1511	domain protein
D9C11_05885	COG0433	COG0433 Predicted ATPase
D9C11_05885	COG1674	ftsk spoiiie
D9C11_05890	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9C11_05895	COG5417	Belongs to the EsaB family
D9C11_05900	COG4842	Belongs to the WXG100 family
D9C11_05915	COG0686	Belongs to the AlaDH PNT family
D9C11_05920	COG5634	Uncharacterized conserved protein (DUF2278)
D9C11_05925	COG3251	PFAM MbtH domain protein
D9C11_05930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C11_05935	COG3433	isochorismatase activity
D9C11_05935	COG1535	isochorismatase
D9C11_05940	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9C11_05945	COG1169	isochorismate synthase
D9C11_05950	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_05955	COG2819	hydrolase of the alpha beta superfamily
D9C11_05965	COG1268	BioY protein
D9C11_05970	COG2056	Na+-H+ antiporter family
D9C11_05975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9C11_05980	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9C11_05985	COG3584	3D domain protein
D9C11_06005	COG1252	NADH dehydrogenase
D9C11_06010	COG0492	ferredoxin-NADP+ reductase activity
D9C11_06020	COG0516	GMP reductase activity
D9C11_06035	COG0316	Belongs to the HesB IscA family
D9C11_06040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9C11_06045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C11_06050	COG4844	belongs to the
D9C11_06055	COG1252	NADH dehydrogenase
D9C11_06060	COG4837	Protein of unknown function (DUF1462)
D9C11_06065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9C11_06070	COG4946	Tricorn protease homolog
D9C11_06070	COG1506	peptidase
D9C11_06070	COG0823	Involved in the tonB-independent uptake of proteins
D9C11_06075	COG0083	homoserine kinase activity
D9C11_06080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9C11_06085	COG0460	homoserine dehydrogenase
D9C11_06095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9C11_06100	COG0647	UMP catabolic process
D9C11_06105	COG2445	Protein of unknown function DUF86
D9C11_06110	COG4470	Protein conserved in bacteria
D9C11_06120	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9C11_06125	COG0739	heme binding
D9C11_06135	COG3377	Domain of unknown function (DUF1805)
D9C11_06140	COG0737	Belongs to the 5'-nucleotidase family
D9C11_06145	COG0730	response to heat
D9C11_06150	COG1801	Protein of unknown function DUF72
D9C11_06160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C11_06165	COG2508	Transcriptional regulator
D9C11_06170	COG2233	PERMEase
D9C11_06175	COG2233	PERMEase
D9C11_06180	COG3648	Uricase
D9C11_06180	COG3195	allantoin biosynthetic process
D9C11_06185	COG2351	hydroxyisourate hydrolase activity
D9C11_06195	COG2080	2 iron, 2 sulfur cluster binding
D9C11_06200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9C11_06205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9C11_06210	COG2068	MobA-Related Protein
D9C11_06215	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9C11_06220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9C11_06225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C11_06235	COG2356	endonuclease I
D9C11_06265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_06285	COG3842	ATPase activity
D9C11_06290	COG2188	Transcriptional regulator
D9C11_06295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C11_06305	COG1175	transmembrane transport
D9C11_06315	COG2222	sugar isomerase
D9C11_06320	COG0322	excinuclease ABC activity
D9C11_06325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C11_06345	COG0346	lactoylglutathione lyase activity
D9C11_06350	COG0640	Transcriptional regulator
D9C11_06380	COG5444	nuclease activity
D9C11_06390	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_06390	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_06395	COG4824	toxin secretion phage lysis holin
D9C11_06430	COG5412	phage tail tape measure protein
D9C11_06430	COG3953	SLT domain
D9C11_06525	COG0582	viral genome integration into host DNA
D9C11_06605	COG1396	sequence-specific DNA binding
D9C11_06605	COG3800	Transcriptional regulator
D9C11_06625	COG0719	Fe-S assembly protein
D9C11_06630	COG0822	iron-sulfur transferase activity
D9C11_06635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C11_06640	COG0719	Fe-S assembly protein
D9C11_06645	COG0396	ATPase activity
D9C11_06665	COG1464	Belongs to the NlpA lipoprotein family
D9C11_06670	COG2011	ABC-type metal ion transport system permease component
D9C11_06675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9C11_06685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_06690	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C11_06700	COG0509	glycine decarboxylation via glycine cleavage system
D9C11_06705	COG1393	Belongs to the ArsC family
D9C11_06710	COG1960	acyl-CoA dehydrogenase activity
D9C11_06715	COG0183	Belongs to the thiolase family
D9C11_06720	COG1024	Enoyl-CoA hydratase
D9C11_06720	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9C11_06730	COG0506	proline dehydrogenase activity
D9C11_06740	COG5577	PFAM Coat F domain
D9C11_06745	COG1846	Transcriptional regulator
D9C11_06750	COG0477	Major facilitator Superfamily
D9C11_06755	COG1942	4-Oxalocrotonate Tautomerase
D9C11_06760	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_06765	COG0583	DNA-binding transcription factor activity
D9C11_06775	COG1120	ATPase activity
D9C11_06790	COG3328	transposase activity
D9C11_06805	COG1131	(ABC) transporter
D9C11_06855	COG0783	Belongs to the Dps family
D9C11_06860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C11_06865	COG0745	RESPONSE REGULATOR receiver
D9C11_06870	COG2770	Histidine kinase
D9C11_06870	COG2205	protein histidine kinase activity
D9C11_06880	COG1309	transcriptional regulator
D9C11_06885	COG0114	fumarate hydratase activity
D9C11_06895	COG0697	spore germination
D9C11_06900	COG0814	amino acid
D9C11_06910	COG2197	response regulator
D9C11_06915	COG4585	Histidine kinase
D9C11_06920	COG4758	membrane
D9C11_06925	COG3595	metallopeptidase activity
D9C11_06930	COG1842	Phage shock protein A
D9C11_06935	COG4758	membrane
D9C11_06940	COG2814	Major facilitator Superfamily
D9C11_06945	COG2096	Adenosyltransferase
D9C11_06950	COG1120	ATPase activity
D9C11_06955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C11_06960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C11_06965	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_06970	COG3386	PFAM SMP-30 Gluconolaconase
D9C11_06975	COG2205	protein histidine kinase activity
D9C11_06980	COG0745	RESPONSE REGULATOR receiver
D9C11_06990	COG1191	sigma factor activity
D9C11_07000	COG2140	Oxalate decarboxylase
D9C11_07010	COG0577	efflux transmembrane transporter activity
D9C11_07015	COG1136	(ABC) transporter
D9C11_07020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C11_07025	COG1120	ATPase activity
D9C11_07035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C11_07040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C11_07050	COG0531	amino acid
D9C11_07065	COG1988	membrane-bound metal-dependent
D9C11_07070	COG1368	sulfuric ester hydrolase activity
D9C11_07075	COG1910	domain protein
D9C11_07080	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9C11_07085	COG4149	molybdate abc transporter
D9C11_07090	COG0656	L-ascorbic acid biosynthetic process
D9C11_07100	COG0025	NhaP-type Na H and K H
D9C11_07105	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C11_07110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C11_07115	COG3973	AAA domain
D9C11_07120	COG2860	membrane
D9C11_07130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9C11_07135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9C11_07140	COG2217	Heavy metal translocating P-type atpase
D9C11_07145	COG2217	Heavy metal translocating P-type atpase
D9C11_07150	COG2608	mercury ion transmembrane transporter activity
D9C11_07155	COG1937	Protein conserved in bacteria
D9C11_07160	COG0673	inositol 2-dehydrogenase activity
D9C11_07170	COG1289	transmembrane transporter activity
D9C11_07180	COG2076	Multidrug Resistance protein
D9C11_07185	COG1309	transcriptional regulator
D9C11_07195	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_07205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9C11_07210	COG0557	exoribonuclease II activity
D9C11_07215	COG1647	Serine aminopeptidase, S33
D9C11_07220	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C11_07225	COG0596	Alpha beta hydrolase
D9C11_07230	COG1476	TRANSCRIPTIONal
D9C11_07235	COG1396	sequence-specific DNA binding
D9C11_07240	COG1396	sequence-specific DNA binding
D9C11_07245	COG1733	regulation of RNA biosynthetic process
D9C11_07255	COG1174	glycine betaine transport
D9C11_07260	COG1732	Glycine betaine
D9C11_07265	COG1174	glycine betaine transport
D9C11_07270	COG1125	glycine betaine transport
D9C11_07270	COG0517	IMP dehydrogenase activity
D9C11_07275	COG1510	regulation of RNA biosynthetic process
D9C11_07280	COG1174	glycine betaine transport
D9C11_07285	COG1732	Glycine betaine
D9C11_07290	COG1174	glycine betaine transport
D9C11_07295	COG1125	glycine betaine transport
D9C11_07295	COG0517	IMP dehydrogenase activity
D9C11_07300	COG1510	regulation of RNA biosynthetic process
D9C11_07305	COG2095	MarC family integral membrane protein
D9C11_07315	COG3064	Membrane
D9C11_07320	COG4640	response to antibiotic
D9C11_07325	COG0456	acetyltransferase
D9C11_07330	COG0148	phosphopyruvate hydratase activity
D9C11_07335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9C11_07340	COG0149	triose-phosphate isomerase activity
D9C11_07345	COG0126	phosphoglycerate kinase activity
D9C11_07350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9C11_07355	COG2390	Transcriptional regulator
D9C11_07360	COG2814	Major facilitator Superfamily
D9C11_07365	COG1609	Transcriptional regulator
D9C11_07370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C11_07380	COG0583	DNA-binding transcription factor activity
D9C11_07385	COG0697	spore germination
D9C11_07390	COG1113	amino acid transport
D9C11_07400	COG1556	Lactate utilization protein
D9C11_07405	COG1139	Iron-sulfur cluster binding protein
D9C11_07410	COG0247	lactate metabolic process
D9C11_07415	COG2197	response regulator
D9C11_07420	COG4585	Histidine kinase
D9C11_07425	COG0842	Transport permease protein
D9C11_07430	COG1131	(ABC) transporter
D9C11_07435	COG0596	Alpha beta hydrolase
D9C11_07440	COG2208	phosphoserine phosphatase activity
D9C11_07445	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9C11_07450	COG1874	Beta-galactosidase
D9C11_07455	COG3833	ABC-type maltose transport systems, permease component
D9C11_07460	COG1175	transmembrane transport
D9C11_07465	COG2182	Extracellular solute-binding protein
D9C11_07470	COG1609	Transcriptional regulator
D9C11_07475	COG2186	Transcriptional regulator
D9C11_07480	COG1620	l-lactate permease
D9C11_07485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9C11_07495	COG5039	Polysaccharide pyruvyl transferase
D9C11_07500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C11_07505	COG0110	maltose O-acetyltransferase activity
D9C11_07510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9C11_07515	COG2244	polysaccharide biosynthetic process
D9C11_07520	COG1216	Glycosyl transferase, family 2
D9C11_07525	COG5039	Polysaccharide pyruvyl transferase
D9C11_07530	COG1216	Glycosyl transferase, family 2
D9C11_07540	COG0438	transferase activity, transferring glycosyl groups
D9C11_07545	COG1215	transferase activity, transferring glycosyl groups
D9C11_07550	COG0438	transferase activity, transferring glycosyl groups
D9C11_07555	COG1086	Polysaccharide biosynthesis protein
D9C11_07560	COG0489	protein tyrosine kinase activity
D9C11_07565	COG3944	biosynthesis protein
D9C11_07570	COG1396	sequence-specific DNA binding
D9C11_07575	COG2272	Belongs to the type-B carboxylesterase lipase family
D9C11_07585	COG3479	Phenolic acid decarboxylase
D9C11_07600	COG1794	racemase activity, acting on amino acids and derivatives
D9C11_07605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C11_07610	COG1621	beta-fructofuranosidase activity
D9C11_07615	COG1621	beta-fructofuranosidase activity
D9C11_07620	COG0531	amino acid
D9C11_07625	COG1309	transcriptional regulator
D9C11_07630	COG2076	Multidrug Resistance protein
D9C11_07635	COG2076	Multidrug Resistance protein
D9C11_07650	COG0740	serine-type endopeptidase activity
D9C11_07655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C11_07660	COG0366	Alpha amylase catalytic
D9C11_07665	COG1554	hydrolase, family 65, central catalytic
D9C11_07675	COG1175	transmembrane transport
D9C11_07680	COG2182	Extracellular solute-binding protein
D9C11_07685	COG0366	Alpha amylase catalytic
D9C11_07690	COG1609	Transcriptional regulator
D9C11_07695	COG1611	Belongs to the LOG family
D9C11_07705	COG0659	secondary active sulfate transmembrane transporter activity
D9C11_07710	COG0288	reversible hydration of carbon dioxide
D9C11_07715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C11_07720	COG0577	efflux transmembrane transporter activity
D9C11_07725	COG1136	(ABC) transporter
D9C11_07730	COG5002	protein histidine kinase activity
D9C11_07735	COG0745	RESPONSE REGULATOR receiver
D9C11_07745	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9C11_07750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C11_07755	COG1481	regulation of sporulation
D9C11_07760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9C11_07765	COG1660	Displays ATPase and GTPase activities
D9C11_07770	COG1051	belongs to the nudix hydrolase family
D9C11_07775	COG0492	ferredoxin-NADP+ reductase activity
D9C11_07780	COG3883	PFAM NLP P60 protein
D9C11_07780	COG0791	NLP P60 protein
D9C11_07785	COG0457	Tetratricopeptide repeat
D9C11_07790	COG1132	(ABC) transporter
D9C11_07820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9C11_07820	COG0140	phosphoribosyl-ATP diphosphatase activity
D9C11_07825	COG0107	imidazoleglycerol-phosphate synthase activity
D9C11_07830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9C11_07835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9C11_07840	COG0131	Imidazoleglycerol-phosphate dehydratase
D9C11_07845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9C11_07850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9C11_07855	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9C11_07860	COG4990	cell redox homeostasis
D9C11_07865	COG5297	Belongs to the glycosyl hydrolase family 6
D9C11_07870	COG0110	maltose O-acetyltransferase activity
D9C11_07875	COG0546	phosphoglycolate phosphatase activity
D9C11_07880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9C11_07885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9C11_07890	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9C11_07895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9C11_07900	COG0363	glucosamine-6-phosphate deaminase activity
D9C11_07910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9C11_07915	COG1846	Transcriptional regulator
D9C11_07920	COG2814	Major facilitator Superfamily
D9C11_07930	COG1950	PFAM Membrane protein of
D9C11_07935	COG1983	PspC domain protein
D9C11_07940	COG3595	metallopeptidase activity
D9C11_07955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C11_07960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9C11_07965	COG0556	nucleotide-excision repair
D9C11_07970	COG4897	Protein conserved in bacteria
D9C11_07975	COG3848	Pyruvate phosphate dikinase
D9C11_07975	COG0574	Belongs to the PEP-utilizing enzyme family
D9C11_07980	COG1309	transcriptional regulator
D9C11_07985	COG2814	Major facilitator Superfamily
D9C11_07990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C11_08000	COG0793	Belongs to the peptidase S41A family
D9C11_08000	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_08005	COG2177	Part of the ABC transporter FtsEX involved in
D9C11_08010	COG2884	Cell division ATP-binding protein ftsE
D9C11_08035	COG0494	nUDIX hydrolase
D9C11_08080	COG2010	Cytochrome c
D9C11_08085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C11_08095	COG0653	protein targeting
D9C11_08105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9C11_08120	COG1516	flagellar protein fliS
D9C11_08125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9C11_08130	COG1334	flagellar protein FlaG
D9C11_08135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C11_08140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9C11_08145	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9C11_08155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9C11_08160	COG1256	bacterial-type flagellum assembly
D9C11_08160	COG4786	Flagellar basal body rod
D9C11_08165	COG3418	PFAM FlgN family protein
D9C11_08170	COG2747	anti-sigma28 factor FlgM
D9C11_08180	COG1040	competence protein
D9C11_08190	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9C11_08195	COG1307	EDD domain protein, DegV family
D9C11_08200	COG2197	response regulator
D9C11_08205	COG4585	Histidine kinase
D9C11_08210	COG1739	Uncharacterized protein family UPF0029
D9C11_08215	COG1316	TRANSCRIPTIONal
D9C11_08220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C11_08225	COG0438	transferase activity, transferring glycosyl groups
D9C11_08230	COG1215	transferase activity, transferring glycosyl groups
D9C11_08235	COG3206	protein involved in exopolysaccharide biosynthesis
D9C11_08240	COG3307	-O-antigen
D9C11_08250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C11_08255	COG0438	transferase activity, transferring glycosyl groups
D9C11_08255	COG0297	glycogen (starch) synthase activity
D9C11_08260	COG2244	polysaccharide biosynthetic process
D9C11_08275	COG2247	cell wall binding repeat
D9C11_08275	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_08280	COG2247	cell wall binding repeat
D9C11_08280	COG2385	sporulation resulting in formation of a cellular spore
D9C11_08300	COG2801	Transposase and inactivated derivatives
D9C11_08305	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9C11_08310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C11_08320	COG1134	teichoic acid transport
D9C11_08325	COG1682	transport, permease protein
D9C11_08340	COG0463	Glycosyl transferase, family 2
D9C11_08340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C11_08345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C11_08350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9C11_08355	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D9C11_08360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C11_08365	COG4193	domain, Protein
D9C11_08370	COG1482	cell wall glycoprotein biosynthetic process
D9C11_08390	COG2814	Major facilitator Superfamily
D9C11_08395	COG1316	TRANSCRIPTIONal
D9C11_08400	COG0561	phosphatase activity
D9C11_08405	COG0791	NLP P60 protein
D9C11_08415	COG2843	Capsule synthesis protein
D9C11_08425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C11_08435	COG1609	Transcriptional regulator
D9C11_08440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C11_08445	COG1869	D-ribose catabolic process
D9C11_08450	COG1129	ABC transporter
D9C11_08455	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9C11_08460	COG1879	ABC-type sugar transport system periplasmic component
D9C11_08465	COG3103	Sh3 type 3 domain protein
D9C11_08475	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9C11_08480	COG3527	Alpha-acetolactate decarboxylase
D9C11_08485	COG0028	Belongs to the TPP enzyme family
D9C11_08490	COG0583	DNA-binding transcription factor activity
D9C11_08510	COG5337	Spore coat protein CotH
D9C11_08520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C11_08530	COG0405	Gamma-glutamyltransferase
D9C11_08535	COG1522	sequence-specific DNA binding
D9C11_08540	COG2059	Chromate
D9C11_08545	COG2059	Chromate
D9C11_08550	COG1515	deoxyribonuclease V activity
D9C11_08555	COG2849	repeat protein
D9C11_08580	COG3878	Protein conserved in bacteria
D9C11_08590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9C11_08595	COG4464	protein tyrosine phosphatase activity
D9C11_08600	COG0489	protein tyrosine kinase activity
D9C11_08605	COG3944	biosynthesis protein
D9C11_08615	COG4715	Zinc finger, swim domain protein
D9C11_08620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9C11_08630	COG0561	phosphatase activity
D9C11_08635	COG1349	DNA-binding transcription factor activity
D9C11_08640	COG0629	single-stranded DNA binding
D9C11_08655	COG3764	Sortase (surface protein transpeptidase)
D9C11_08665	COG0745	RESPONSE REGULATOR receiver
D9C11_08665	COG2972	Histidine kinase
D9C11_08670	COG1970	mechanosensitive ion channel activity
D9C11_08675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C11_08680	COG0457	Tetratricopeptide repeat
D9C11_08685	COG4786	Flagellar basal body rod
D9C11_08690	COG4786	Flagellar basal body rod
D9C11_08695	COG1077	Cell shape determining protein MreB Mrl
D9C11_08700	COG1609	Transcriptional regulator
D9C11_08710	COG1846	Transcriptional regulator
D9C11_08715	COG2814	Major facilitator Superfamily
D9C11_08720	COG3420	alginic acid biosynthetic process
D9C11_08725	COG1953	Uracil, thiamine, allantoin
D9C11_08730	COG0477	Major facilitator Superfamily
D9C11_08735	COG1335	isochorismatase
D9C11_08745	COG0004	ammonium transporteR
D9C11_08750	COG0347	Belongs to the P(II) protein family
D9C11_08755	COG0671	phosphoesterase, PA-phosphatase related
D9C11_08765	COG0739	heme binding
D9C11_08770	COG1247	-acetyltransferase
D9C11_08790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C11_08795	COG0789	Transcriptional regulator
D9C11_08815	COG1959	2 iron, 2 sulfur cluster binding
D9C11_08820	COG0804	urea catabolic process
D9C11_08825	COG0832	Belongs to the urease beta subunit family
D9C11_08830	COG0831	urea catabolic process
D9C11_08845	COG3237	CsbD-like
D9C11_08850	COG1994	Peptidase M50
D9C11_08865	COG0457	Tetratricopeptide repeat
D9C11_08875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9C11_08880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9C11_08890	COG2304	oxidoreductase activity
D9C11_08900	COG2304	oxidoreductase activity
D9C11_08905	COG2385	sporulation resulting in formation of a cellular spore
D9C11_08910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C11_08920	COG4836	Membrane
D9C11_08930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9C11_08935	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9C11_08940	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9C11_08945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9C11_08950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C11_08955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9C11_08960	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9C11_08965	COG0356	it plays a direct role in the translocation of protons across the membrane
D9C11_08975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9C11_08980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9C11_08985	COG4475	Protein of unknown function (DUF436)
D9C11_08990	COG0698	ribose 5-phosphate isomerase
D9C11_08995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C11_09000	COG1971	Probably functions as a manganese efflux pump
D9C11_09005	COG0009	L-threonylcarbamoyladenylate synthase
D9C11_09010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9C11_09030	COG2890	protein-(glutamine-N5) methyltransferase activity
D9C11_09035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9C11_09040	COG0346	lactoylglutathione lyase activity
D9C11_09045	COG0789	Transcriptional regulator
D9C11_09050	COG0679	Auxin Efflux Carrier
D9C11_09055	COG0281	malic enzyme
D9C11_09060	COG1435	thymidine kinase activity
D9C11_09065	COG0254	rRNA binding
D9C11_09070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9C11_09080	COG1494	fructose-1,6-bisphosphatase
D9C11_09085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9C11_09090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9C11_09095	COG0191	fructose-bisphosphate aldolase activity
D9C11_09100	COG2204	response regulator
D9C11_09105	COG4821	SIS domain
D9C11_09115	COG0504	CTP synthase activity
D9C11_09120	COG3343	RNA polymerase activity
D9C11_09125	COG1960	acyl-CoA dehydrogenase activity
D9C11_09130	COG0247	lactate metabolic process
D9C11_09130	COG2181	nitrate reductase activity
D9C11_09135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C11_09140	COG4294	response to UV
D9C11_09155	COG0018	arginyl-trna synthetase
D9C11_09160	COG4506	Protein conserved in bacteria
D9C11_09175	COG0535	radical SAM domain protein
D9C11_09185	COG1131	(ABC) transporter
D9C11_09190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C11_09195	COG0612	Peptidase, M16
D9C11_09200	COG0612	Peptidase, M16
D9C11_09210	COG3391	amine dehydrogenase activity
D9C11_09215	COG3391	amine dehydrogenase activity
D9C11_09225	COG0457	Tetratricopeptide repeat
D9C11_09240	COG0010	Belongs to the arginase family
D9C11_09245	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9C11_09250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C11_09265	COG1994	Peptidase M50
D9C11_09270	COG1942	4-Oxalocrotonate Tautomerase
D9C11_09275	COG1846	Transcriptional regulator
D9C11_09280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9C11_09290	COG0477	Major facilitator Superfamily
D9C11_09295	COG1959	2 iron, 2 sulfur cluster binding
D9C11_09300	COG3465	dGTPase activity
D9C11_09305	COG1078	dGTPase activity
D9C11_09310	COG4844	belongs to the
D9C11_09320	COG0697	spore germination
D9C11_09325	COG0095	Lipoate-protein ligase
D9C11_09330	COG0583	DNA-binding transcription factor activity
D9C11_09335	COG0280	phosphate acetyltransferase
D9C11_09345	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_09350	COG0436	Aminotransferase
D9C11_09365	COG0833	amino acid
D9C11_09370	COG4187	Peptidase family M20/M25/M40
D9C11_09375	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_09380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9C11_09390	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D9C11_09395	COG1091	dTDP-4-dehydrorhamnose reductase activity
D9C11_09400	COG1088	dTDP-glucose 4,6-dehydratase activity
D9C11_09405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D9C11_09410	COG3980	spore coat polysaccharide biosynthesis protein
D9C11_09415	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D9C11_09420	COG2089	acid synthase
D9C11_09425	COG0456	acetyltransferase
D9C11_09430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9C11_09435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9C11_09440	COG0463	Glycosyl transferase, family 2
D9C11_09455	COG2363	Small membrane protein
D9C11_09460	COG2233	PERMEase
D9C11_09470	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_09475	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9C11_09480	COG1216	Glycosyl transferase, family 2
D9C11_09495	COG1695	Transcriptional regulator
D9C11_09500	COG0351	phosphomethylpyrimidine kinase
D9C11_09510	COG1621	beta-fructofuranosidase activity
D9C11_09515	COG1263	PTS System
D9C11_09515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_09520	COG2116	formate transmembrane transporter activity
D9C11_09525	COG3711	transcriptional antiterminator
D9C11_09545	COG0778	Nitroreductase
D9C11_09550	COG0772	Belongs to the SEDS family
D9C11_09560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C11_09565	COG1845	cytochrome c oxidase, subunit III
D9C11_09570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C11_09575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C11_09580	COG2261	transglycosylase associated protein
D9C11_09585	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9C11_09590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9C11_09595	COG2246	polysaccharide biosynthetic process
D9C11_09600	COG1309	transcriptional regulator
D9C11_09610	COG3162	membrane
D9C11_09615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C11_09620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9C11_09625	COG2837	iron assimilation
D9C11_09630	COG2822	iron ion transport
D9C11_09635	COG0672	)-iron permease
D9C11_09640	COG0352	thiamine-phosphate diphosphorylase activity
D9C11_09645	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9C11_09650	COG0583	DNA-binding transcription factor activity
D9C11_09655	COG1380	Effector of murein hydrolase LrgA
D9C11_09660	COG1346	cytolysis
D9C11_09665	COG2814	Major facilitator Superfamily
D9C11_09670	COG4895	conserved protein (DUF2196)
D9C11_09675	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9C11_09680	COG0346	lactoylglutathione lyase activity
D9C11_09690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C11_09695	COG1404	Belongs to the peptidase S8 family
D9C11_09700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_09700	COG1263	PTS System
D9C11_09705	COG3711	transcriptional antiterminator
D9C11_09710	COG1442	glycosyl transferase family 8
D9C11_09720	COG1846	Transcriptional regulator
D9C11_09725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9C11_09735	COG2357	RelA SpoT domain protein
D9C11_09745	COG1575	Belongs to the MenA family. Type 1 subfamily
D9C11_09765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C11_09770	COG1696	Membrane protein involved in D-alanine export
D9C11_09775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C11_09780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9C11_09790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C11_09795	COG1486	melibiose metabolic process
D9C11_09800	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9C11_09805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C11_09810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C11_09815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C11_09815	COG3711	transcriptional antiterminator
D9C11_09825	COG2094	Belongs to the DNA glycosylase MPG family
D9C11_09830	COG0753	catalase activity
D9C11_09840	COG1131	(ABC) transporter
D9C11_09860	COG1595	DNA-templated transcription, initiation
D9C11_09865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C11_09870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9C11_09875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9C11_09880	COG4988	ABC transporter
D9C11_09885	COG1294	oxidase, subunit
D9C11_09890	COG1271	oxidase subunit
D9C11_09895	COG3493	citrate carrier protein
D9C11_09900	COG0501	Belongs to the peptidase M48B family
D9C11_09910	COG0726	polysaccharide deacetylase
D9C11_09915	COG3842	ATPase activity
D9C11_09920	COG2508	Transcriptional regulator
D9C11_09925	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_09930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C11_09945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9C11_09955	COG4585	Histidine kinase
D9C11_09960	COG2197	response regulator
D9C11_09965	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9C11_09975	COG4894	glucomannan catabolic process
D9C11_09980	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C11_09985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C11_09990	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_09995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9C11_10000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C11_10005	COG2610	gluconate transmembrane transporter activity
D9C11_10010	COG0500	methyltransferase
D9C11_10015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C11_10030	COG0753	catalase activity
D9C11_10030	COG0693	protein deglycase activity
D9C11_10035	COG2851	Citrate transporter
D9C11_10040	COG2273	Hydrolase Family 16
D9C11_10055	COG2270	Major facilitator Superfamily
D9C11_10060	COG0513	Belongs to the DEAD box helicase family
D9C11_10065	COG2755	lipolytic protein G-D-S-L family
D9C11_10065	COG3401	FG-GAP repeat protein
D9C11_10185	COG0697	spore germination
D9C11_10190	COG0589	response to stress
D9C11_10210	COG5444	nuclease activity
D9C11_10240	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9C11_10245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9C11_10250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9C11_10255	COG2390	Transcriptional regulator
D9C11_10285	COG1131	(ABC) transporter
D9C11_10300	COG0561	phosphatase activity
D9C11_10310	COG3192	ethanolamine utilization protein
D9C11_10315	COG2079	MmgE PrpD family protein
D9C11_10325	COG1126	abc transporter atp-binding protein
D9C11_10330	COG0765	amino acid transport
D9C11_10335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C11_10350	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9C11_10355	COG0561	phosphatase activity
D9C11_10385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C11_10390	COG5294	Protein conserved in bacteria
D9C11_10395	COG0577	efflux transmembrane transporter activity
D9C11_10400	COG1136	(ABC) transporter
D9C11_10405	COG2205	protein histidine kinase activity
D9C11_10415	COG2205	protein histidine kinase activity
D9C11_10420	COG0745	RESPONSE REGULATOR receiver
D9C11_10465	COG0191	fructose-bisphosphate aldolase activity
D9C11_10470	COG1082	Xylose isomerase domain protein TIM barrel
D9C11_10475	COG1082	Xylose isomerase domain protein TIM barrel
D9C11_10480	COG0673	inositol 2-dehydrogenase activity
D9C11_10490	COG1082	Xylose isomerase domain protein TIM barrel
D9C11_10495	COG3962	Belongs to the TPP enzyme family
D9C11_10500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C11_10515	COG1349	DNA-binding transcription factor activity
D9C11_10520	COG0667	Aldo Keto reductase
D9C11_10540	COG0326	Molecular chaperone. Has ATPase activity
D9C11_10605	COG1917	Cupin 2, conserved barrel domain protein
D9C11_10610	COG1309	transcriptional regulator
D9C11_10615	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_10620	COG1846	Transcriptional regulator
D9C11_10625	COG1380	Effector of murein hydrolase LrgA
D9C11_10630	COG1346	cytolysis
D9C11_10635	COG5039	Polysaccharide pyruvyl transferase
D9C11_10640	COG1929	Belongs to the glycerate kinase type-1 family
D9C11_10645	COG1802	Transcriptional regulator
D9C11_10650	COG1070	Carbohydrate kinase
D9C11_10655	COG2610	gluconate transmembrane transporter activity
D9C11_10660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9C11_10665	COG0450	alkyl hydroperoxide reductase
D9C11_10670	COG3634	alkyl hydroperoxide reductase activity
D9C11_10675	COG2723	6-phospho-beta-galactosidase activity
D9C11_10680	COG2190	(PTS) system
D9C11_10690	COG2188	Transcriptional regulator
D9C11_10705	COG1131	(ABC) transporter
D9C11_10710	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
D9C11_10725	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C11_10760	COG0210	DNA helicase
D9C11_10815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9C11_10830	COG1063	alcohol dehydrogenase
D9C11_10850	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D9C11_10855	COG0456	acetyltransferase
D9C11_10860	COG0457	Tetratricopeptide repeat
D9C11_10870	COG0010	Belongs to the arginase family
D9C11_10875	COG0833	amino acid
D9C11_10880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C11_10885	COG3829	transcription factor binding
D9C11_10900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C11_10905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9C11_10910	COG4853	Protein conserved in bacteria
D9C11_10915	COG4863	YycH protein
D9C11_10920	COG5002	protein histidine kinase activity
D9C11_10925	COG0745	RESPONSE REGULATOR receiver
D9C11_10955	COG0346	lactoylglutathione lyase activity
D9C11_10960	COG0305	Participates in initiation and elongation during chromosome replication
D9C11_10975	COG3093	addiction module antidote protein HigA
D9C11_10980	COG2807	transmembrane transport
D9C11_10985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C11_10990	COG0359	binds to the 23S rRNA
D9C11_10995	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9C11_11000	COG4241	membrane
D9C11_11015	COG1733	regulation of RNA biosynthetic process
D9C11_11020	COG1227	inorganic diphosphatase activity
D9C11_11035	COG2271	Major facilitator Superfamily
D9C11_11040	COG0789	Transcriptional regulator
D9C11_11040	COG4978	Transcriptional regulator
D9C11_11050	COG3328	transposase activity
D9C11_11060	COG4319	ketosteroid isomerase
D9C11_11065	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C11_11080	COG1846	Transcriptional regulator
D9C11_11085	COG2153	protein acetylation
D9C11_11090	COG2364	Membrane
D9C11_11095	COG0456	acetyltransferase
D9C11_11105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9C11_11115	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D9C11_11120	COG1331	Highly conserved protein containing a thioredoxin domain
D9C11_11125	COG1266	CAAX protease self-immunity
D9C11_11130	COG0477	Major facilitator Superfamily
D9C11_11130	COG2814	Major facilitator Superfamily
D9C11_11135	COG0110	maltose O-acetyltransferase activity
D9C11_11140	COG0346	lactoylglutathione lyase activity
D9C11_11150	COG0708	Exodeoxyribonuclease III
D9C11_11155	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9C11_11160	COG0629	single-stranded DNA binding
D9C11_11165	COG0360	Binds together with S18 to 16S ribosomal RNA
D9C11_11170	COG0012	GTP binding
D9C11_11175	COG0243	molybdopterin cofactor binding
D9C11_11180	COG4481	Protein conserved in bacteria
D9C11_11185	COG3949	Membrane
D9C11_11200	COG1475	DNA binding
D9C11_11205	COG1192	Involved in chromosome partitioning
D9C11_11215	COG1475	DNA binding
D9C11_11220	COG0357	Ribosomal RNA small subunit methyltransferase G
D9C11_11225	COG0445	tRNA wobble uridine modification
D9C11_11230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9C11_11235	COG1847	R3H domain protein
D9C11_11240	COG0706	membrane insertase activity
D9C11_11245	COG0594	ribonuclease P activity
D9C11_11250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D9C11_11255	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9C11_11260	COG0592	DNA-directed DNA polymerase activity
D9C11_11265	COG2501	S4 domain
D9C11_11270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9C11_11280	COG0187	DNA topoisomerase II activity
D9C11_11285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C11_11320	COG0517	IMP dehydrogenase activity
D9C11_11320	COG0516	GMP reductase activity
D9C11_11325	COG1686	Belongs to the peptidase S11 family
D9C11_11330	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9C11_11335	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9C11_11340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9C11_11350	COG1428	Deoxynucleoside kinase
D9C11_11355	COG1428	Deoxynucleoside kinase
D9C11_11360	COG3858	chitin binding
D9C11_11360	COG1388	LysM domain
D9C11_11365	COG1335	isochorismatase
D9C11_11370	COG0590	tRNA wobble adenosine to inosine editing
D9C11_11380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9C11_11385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9C11_11390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9C11_11435	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9C11_11440	COG3853	Toxic anion resistance protein (TelA)
D9C11_11445	COG1982	Orn Lys Arg decarboxylase major
D9C11_11450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9C11_11455	COG3870	Protein conserved in bacteria
D9C11_11460	COG1728	Protein conserved in bacteria
D9C11_11465	COG0470	DNA polymerase III
D9C11_11470	COG1774	PSP1 C-terminal conserved region
D9C11_11475	COG4467	Involved in initiation control of chromosome replication
D9C11_11480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9C11_11485	COG2827	Endonuclease containing a URI domain
D9C11_11490	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9C11_11495	COG2002	toxin-antitoxin pair type II binding
D9C11_11500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C11_11500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C11_11505	COG0084	hydrolase, TatD family'
D9C11_11510	COG3584	3D domain protein
D9C11_11510	COG3583	domain protein
D9C11_11515	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9C11_11520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9C11_11530	COG4466	Protein conserved in bacteria
D9C11_11540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9C11_11545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9C11_11550	COG0251	oxidation-reduction process
D9C11_11555	COG2088	sporulation resulting in formation of a cellular spore
D9C11_11560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9C11_11565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9C11_11570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9C11_11575	COG0193	aminoacyl-tRNA hydrolase activity
D9C11_11585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9C11_11590	COG2002	toxin-antitoxin pair type II binding
D9C11_11595	COG2244	polysaccharide biosynthetic process
D9C11_11600	COG3956	TIGRFAM MazG family protein
D9C11_11605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9C11_11620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9C11_11625	COG1098	S1 RNA binding domain
D9C11_11640	COG2208	phosphoserine phosphatase activity
D9C11_11645	COG2304	oxidoreductase activity
D9C11_11650	COG0515	serine threonine protein kinase
D9C11_11655	COG0037	tRNA processing
D9C11_11665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9C11_11670	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9C11_11675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9C11_11680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C11_11685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9C11_11690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9C11_11695	COG0512	Glutamine amidotransferase of anthranilate synthase
D9C11_11700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C11_11705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9C11_11710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9C11_11715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9C11_11720	COG1396	sequence-specific DNA binding
D9C11_11725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C11_11730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9C11_11810	COG4463	regulation of RNA biosynthetic process
D9C11_11815	COG3880	PFAM UvrB UvrC protein
D9C11_11820	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9C11_11825	COG0542	response to heat
D9C11_11830	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9C11_11835	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9C11_11840	COG4956	integral membrane protein (PIN domain superfamily)
D9C11_11845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9C11_11850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9C11_11855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9C11_11865	COG1045	serine acetyltransferase
D9C11_11870	COG0215	cysteine-tRNA ligase activity
D9C11_11875	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9C11_11880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9C11_11885	COG3688	RNA-binding protein containing a PIN domain
D9C11_11890	COG1595	DNA-templated transcription, initiation
D9C11_11895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9C11_11900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9C11_11905	COG0250	Participates in transcription elongation, termination and antitermination
D9C11_11910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9C11_11915	COG0081	regulation of translation
D9C11_11920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9C11_11925	COG0222	ribosome binding
D9C11_11930	COG2813	Specifically methylates the guanine in position
D9C11_11935	COG0085	RNA polymerase activity
D9C11_11940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9C11_11945	COG1358	cellular component organization or biogenesis
D9C11_11950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9C11_11955	COG0049	tRNA binding
D9C11_11960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9C11_11965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9C11_11970	COG0596	Alpha beta hydrolase
D9C11_11975	COG0051	transcription antitermination factor activity, RNA binding
D9C11_11980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9C11_11985	COG0088	Forms part of the polypeptide exit tunnel
D9C11_11990	COG0089	rRNA binding
D9C11_11995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9C11_12000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9C11_12005	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9C11_12010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9C11_12015	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9C11_12020	COG0255	Belongs to the universal ribosomal protein uL29 family
D9C11_12025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9C11_12030	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9C11_12040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9C11_12050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9C11_12055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9C11_12060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9C11_12065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9C11_12070	COG1841	ribosomal large subunit assembly
D9C11_12080	COG0201	protein transport
D9C11_12085	COG0563	adenylate kinase activity
D9C11_12090	COG0024	Methionine aminopeptidase
D9C11_12095	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9C11_12100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9C11_12105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9C11_12110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9C11_12115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9C11_12120	COG0202	RNA polymerase activity
D9C11_12125	COG0203	ribosomal protein L17
D9C11_12130	COG1122	ATPase activity
D9C11_12135	COG1122	ATPase activity
D9C11_12140	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C11_12145	COG0101	tRNA pseudouridine synthase activity
D9C11_12150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9C11_12155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9C11_12160	COG2226	methyltransferase
D9C11_12170	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_12175	COG0489	protein tyrosine kinase activity
D9C11_12185	COG2194	sulfuric ester hydrolase activity
D9C11_12190	COG0726	polysaccharide deacetylase
D9C11_12275	COG0659	secondary active sulfate transmembrane transporter activity
D9C11_12280	COG0385	Bile acid
D9C11_12285	COG2819	hydrolase of the alpha beta superfamily
D9C11_12290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C11_12295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C11_12300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C11_12305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C11_12305	COG2207	Transcriptional regulator
D9C11_12310	COG3876	Protein conserved in bacteria
D9C11_12315	COG1472	Belongs to the glycosyl hydrolase 3 family
D9C11_12320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C11_12325	COG1263	PTS System
D9C11_12325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_12330	COG1737	Transcriptional regulator
D9C11_12335	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9C11_12340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_12345	COG1683	Conserved Protein
D9C11_12375	COG1595	DNA-templated transcription, initiation
D9C11_12380	COG5662	AntiSigma factor
D9C11_12385	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C11_12390	COG4856	YbbR-like protein
D9C11_12395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C11_12405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9C11_12415	COG3321	synthase
D9C11_12415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C11_12415	COG0318	PFAM AMP-dependent synthetase and ligase
D9C11_12415	COG0300	oxidoreductase activity
D9C11_12415	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_12440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9C11_12445	COG3002	Belongs to the UPF0753 family
D9C11_12450	COG0288	reversible hydration of carbon dioxide
D9C11_12460	COG5609	conserved protein (DUF2294)
D9C11_12480	COG0515	serine threonine protein kinase
D9C11_12495	COG1113	amino acid transport
D9C11_12510	COG2602	Beta-lactamase
D9C11_12515	COG2124	cytochrome p450
D9C11_12525	COG0531	amino acid
D9C11_12530	COG0584	glycerophosphoryl diester phosphodiesterase
D9C11_12535	COG2271	Major facilitator Superfamily
D9C11_12555	COG2271	Major facilitator Superfamily
D9C11_12565	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_12575	COG2207	Transcriptional regulator
D9C11_12575	COG1917	Cupin 2, conserved barrel domain protein
D9C11_12580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9C11_12585	COG3591	Belongs to the peptidase S1B family
D9C11_12595	COG0596	Alpha beta hydrolase
D9C11_12600	COG1183	phosphatidylcholine synthase activity
D9C11_12605	COG0586	Pfam SNARE associated Golgi protein
D9C11_12610	COG0688	phosphatidylethanolamine metabolic process
D9C11_12630	COG1301	dicarboxylic acid transport
D9C11_12640	COG0363	glucosamine-6-phosphate deaminase activity
D9C11_12655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C11_12670	COG0833	amino acid
D9C11_12675	COG2040	homocysteine
D9C11_12685	COG1115	amino acid carrier protein
D9C11_12700	COG0784	Response regulator, receiver
D9C11_12710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C11_12715	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_12720	COG2271	Major facilitator Superfamily
D9C11_12725	COG4948	Mandelate Racemase Muconate Lactonizing
D9C11_12730	COG2186	Transcriptional regulator
D9C11_12735	COG2721	sulfolactate sulfo-lyase activity
D9C11_12750	COG0697	spore germination
D9C11_12755	COG0745	RESPONSE REGULATOR receiver
D9C11_12760	COG2205	protein histidine kinase activity
D9C11_12765	COG1131	(ABC) transporter
D9C11_12785	COG3773	Cell wall hydrolase
D9C11_12800	COG3328	transposase activity
D9C11_12835	COG3540	Alkaline phosphatase
D9C11_12840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C11_12845	COG0805	protein transport
D9C11_12850	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D9C11_12855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9C11_12860	COG0477	Major facilitator Superfamily
D9C11_12865	COG1309	transcriptional regulator
D9C11_12870	COG0252	asparaginase activity
D9C11_12875	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C11_12880	COG1714	RDD family
D9C11_12885	COG1405	negative regulation of cell septum assembly
D9C11_12885	COG3012	SEC-C Motif Domain Protein
D9C11_12890	COG3290	protein histidine kinase activity
D9C11_12895	COG3279	Response regulator of the LytR AlgR family
D9C11_12900	COG4555	ABC transporter
D9C11_12905	COG1668	transmembrane transport
D9C11_12910	COG0667	Aldo Keto reductase
D9C11_12925	COG1595	DNA-templated transcription, initiation
D9C11_12930	COG1595	DNA-templated transcription, initiation
D9C11_12935	COG1876	peptidase activity
D9C11_12940	COG0457	Tetratricopeptide repeat
D9C11_12945	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_12955	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9C11_12960	COG1121	(ABC) transporter
D9C11_12965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9C11_12970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9C11_12980	COG2310	stress, protein
D9C11_12985	COG2310	stress, protein
D9C11_12990	COG2310	stress, protein
D9C11_12995	COG0861	Integral membrane protein TerC family
D9C11_13005	COG3853	Toxic anion resistance protein (TelA)
D9C11_13010	COG0477	Major facilitator Superfamily
D9C11_13020	COG2814	Major facilitator Superfamily
D9C11_13025	COG0640	Transcriptional regulator
D9C11_13030	COG4175	Glycine betaine
D9C11_13030	COG0517	IMP dehydrogenase activity
D9C11_13035	COG4176	ABC-type proline glycine betaine transport system permease component
D9C11_13040	COG2113	Glycine betaine
D9C11_13045	COG1473	amidohydrolase
D9C11_13050	COG1288	antiporter activity
D9C11_13065	COG0039	L-malate dehydrogenase activity
D9C11_13080	COG3403	YqcI/YcgG family
D9C11_13095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9C11_13105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9C11_13110	COG2226	methyltransferase
D9C11_13115	COG0583	DNA-binding transcription factor activity
D9C11_13120	COG3458	cephalosporin-C deacetylase activity
D9C11_13130	COG3541	Predicted nucleotidyltransferase
D9C11_13135	COG0506	proline dehydrogenase activity
D9C11_13140	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_13145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C11_13150	COG2508	Transcriptional regulator
D9C11_13155	COG3689	TIGRFAM TIGR03943 family protein
D9C11_13160	COG0701	Predicted permease
D9C11_13165	COG2267	carboxylic ester hydrolase activity
D9C11_13170	COG0492	ferredoxin-NADP+ reductase activity
D9C11_13175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C11_13175	COG1587	Uroporphyrinogen-III synthase
D9C11_13180	COG2146	nitrite reductase [NAD(P)H] activity
D9C11_13185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C11_13190	COG0243	molybdopterin cofactor binding
D9C11_13195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9C11_13200	COG2223	nitrite transmembrane transporter activity
D9C11_13210	COG1376	ErfK ybiS ycfS ynhG family protein
D9C11_13225	COG0765	amino acid transport
D9C11_13230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C11_13240	COG1714	RDD family
D9C11_13250	COG1846	Transcriptional regulator
D9C11_13265	COG2723	6-phospho-beta-galactosidase activity
D9C11_13275	COG3209	COG3209 Rhs family protein
D9C11_13285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9C11_13290	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9C11_13295	COG1733	regulation of RNA biosynthetic process
D9C11_13300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C11_13305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C11_13310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C11_13315	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9C11_13330	COG0697	spore germination
D9C11_13340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_13350	COG2364	Membrane
D9C11_13355	COG1126	abc transporter atp-binding protein
D9C11_13360	COG0765	amino acid transport
D9C11_13365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9C11_13370	COG0583	DNA-binding transcription factor activity
D9C11_13380	COG0596	Alpha beta hydrolase
D9C11_13385	COG3104	oligopeptide transport
D9C11_13390	COG5434	Belongs to the glycosyl hydrolase 28 family
D9C11_13400	COG0697	spore germination
D9C11_13410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9C11_13415	COG1136	(ABC) transporter
D9C11_13420	COG0577	efflux transmembrane transporter activity
D9C11_13425	COG0745	RESPONSE REGULATOR receiver
D9C11_13430	COG5002	protein histidine kinase activity
D9C11_13430	COG3850	Histidine kinase
D9C11_13435	COG0457	Tetratricopeptide repeat
D9C11_13455	COG0527	aspartate kinase activity
D9C11_13460	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C11_13465	COG4605	iron ion homeostasis
D9C11_13470	COG4604	ABC transporter, ATP-binding protein
D9C11_13475	COG4607	ABC-type enterochelin transport system periplasmic component
D9C11_13480	COG2814	Major facilitator Superfamily
D9C11_13485	COG1309	transcriptional regulator
D9C11_13490	COG0778	Nitroreductase
D9C11_13495	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9C11_13500	COG0640	Transcriptional regulator
D9C11_13505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_13510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9C11_13515	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_13520	COG4975	Glucose uptake
D9C11_13525	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_13530	COG4549	nuclear export factor GLE1
D9C11_13535	COG1276	copper resistance
D9C11_13535	COG2372	response to copper ion
D9C11_13540	COG1349	DNA-binding transcription factor activity
D9C11_13550	COG2213	PTS system mannitol-specific
D9C11_13555	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C11_13560	COG0246	Mannitol dehydrogenase
D9C11_13565	COG0473	3-isopropylmalate dehydrogenase activity
D9C11_13570	COG0681	Belongs to the peptidase S26 family
D9C11_13580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9C11_13595	COG0561	phosphatase activity
D9C11_13600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9C11_13605	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C11_13610	COG4336	lyase activity
D9C11_13615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9C11_13620	COG1984	allophanate hydrolase subunit 2
D9C11_13625	COG1414	Transcriptional regulator
D9C11_13630	COG2755	lipolytic protein G-D-S-L family
D9C11_13640	COG2329	Antibiotic biosynthesis monooxygenase
D9C11_13645	COG0768	penicillin binding
D9C11_13650	COG4989	oxidoreductase activity
D9C11_13655	COG3711	transcriptional antiterminator
D9C11_13660	COG0318	PFAM AMP-dependent synthetase and ligase
D9C11_13665	COG2226	methyltransferase
D9C11_13670	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_13675	COG1917	Cupin 2, conserved barrel domain protein
D9C11_13680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_13685	COG3871	stress protein (general stress protein 26)
D9C11_13695	COG2814	Major facilitator Superfamily
D9C11_13700	COG1522	sequence-specific DNA binding
D9C11_13705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C11_13705	COG0551	DNA topoisomerase type I activity
D9C11_13710	COG0494	nUDIX hydrolase
D9C11_13745	COG1914	H( )-stimulated, divalent metal cation uptake system
D9C11_13750	COG2261	transglycosylase associated protein
D9C11_13755	COG4876	unkown
D9C11_13760	COG2217	Heavy metal translocating P-type atpase
D9C11_13770	COG0662	Cupin 2, conserved barrel domain protein
D9C11_13775	COG2329	Antibiotic biosynthesis monooxygenase
D9C11_13785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9C11_13790	COG3290	protein histidine kinase activity
D9C11_13795	COG4565	transcriptional regulatory protein
D9C11_13800	COG1301	dicarboxylic acid transport
D9C11_13810	COG0628	permease
D9C11_13815	COG1131	(ABC) transporter
D9C11_13820	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C11_13830	COG1960	acyl-CoA dehydrogenase activity
D9C11_13850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C11_13855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_13860	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9C11_13865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9C11_13875	COG0513	Belongs to the DEAD box helicase family
D9C11_13880	COG3402	PFAM membrane-flanked domain
D9C11_13885	COG3428	Bacterial PH domain
D9C11_13890	COG0705	Rhomboid family
D9C11_13895	COG0736	holo-[acyl-carrier-protein] synthase activity
D9C11_13900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9C11_13905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9C11_13910	COG0864	Transcriptional regulator
D9C11_13915	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9C11_13920	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C11_13925	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C11_13930	COG2172	sigma factor antagonist activity
D9C11_13935	COG2208	phosphoserine phosphatase activity
D9C11_13940	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C11_13945	COG2172	sigma factor antagonist activity
D9C11_13950	COG1191	sigma factor activity
D9C11_13955	COG2208	phosphoserine phosphatase activity
D9C11_13965	COG2183	response to ionizing radiation
D9C11_13975	COG3091	SprT-like family
D9C11_14015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_14065	COG1476	TRANSCRIPTIONal
D9C11_14100	COG1278	Cold shock
D9C11_14130	COG1329	Transcriptional regulator
D9C11_14145	COG2207	Transcriptional regulator
D9C11_14145	COG1917	Cupin 2, conserved barrel domain protein
D9C11_14150	COG0697	spore germination
D9C11_14160	COG2207	Transcriptional regulator
D9C11_14160	COG3708	Transcriptional regulator
D9C11_14165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_14195	COG1309	transcriptional regulator
D9C11_14200	COG0697	spore germination
D9C11_14205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_14210	COG2030	dehydratase
D9C11_14215	COG3545	Serine hydrolase
D9C11_14225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C11_14230	COG0640	Transcriptional regulator
D9C11_14240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C11_14245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_14260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_14265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9C11_14270	COG0640	Transcriptional regulator
D9C11_14275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9C11_14290	COG4585	Histidine kinase
D9C11_14305	COG2409	Drug exporters of the RND superfamily
D9C11_14315	COG1811	Na channel or pump
D9C11_14320	COG0789	Transcriptional regulator
D9C11_14320	COG4978	Transcriptional regulator
D9C11_14325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C11_14330	COG0778	Nitroreductase
D9C11_14335	COG0346	lactoylglutathione lyase activity
D9C11_14340	COG2259	Doxx family
D9C11_14345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_14380	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C11_14395	COG1309	transcriptional regulator
D9C11_14405	COG0456	acetyltransferase
D9C11_14415	COG1113	amino acid transport
D9C11_14420	COG2318	DinB family
D9C11_14425	COG1846	Transcriptional regulator
D9C11_14430	COG1033	growth of symbiont in host cell
D9C11_14430	COG2409	Drug exporters of the RND superfamily
D9C11_14435	COG0778	Nitroreductase
D9C11_14440	COG1846	Transcriptional regulator
D9C11_14445	COG2814	Major facilitator Superfamily
D9C11_14455	COG0730	response to heat
D9C11_14460	COG1802	Transcriptional regulator
D9C11_14465	COG1388	LysM domain
D9C11_14465	COG3858	chitin binding
D9C11_14470	COG1819	glycosyl
D9C11_14480	COG1785	Belongs to the alkaline phosphatase family
D9C11_14485	COG5646	InterPro IPR014922
D9C11_14495	COG0454	-acetyltransferase
D9C11_14500	COG1078	dGTPase activity
D9C11_14505	COG1388	LysM domain
D9C11_14510	COG2814	Major facilitator Superfamily
D9C11_14515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9C11_14530	COG2723	6-phospho-beta-galactosidase activity
D9C11_14535	COG2188	Transcriptional regulator
D9C11_14540	COG1940	carbohydrate kinase activity
D9C11_14550	COG4124	Belongs to the glycosyl hydrolase 26 family
D9C11_14595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9C11_14600	COG0802	atpase or kinase
D9C11_14605	COG1214	PFAM Peptidase M22, glycoprotease
D9C11_14610	COG0456	acetyltransferase
D9C11_14615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9C11_14620	COG0488	(ABC) transporter
D9C11_14625	COG0315	cyclic pyranopterin monophosphate synthase activity
D9C11_14630	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9C11_14635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C11_14640	COG0805	protein transport
D9C11_14655	COG1266	CAAX protease self-immunity
D9C11_14660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9C11_14665	COG0459	protein refolding
D9C11_14670	COG0745	RESPONSE REGULATOR receiver
D9C11_14685	COG3290	protein histidine kinase activity
D9C11_14765	COG0457	Tetratricopeptide repeat
D9C11_14770	COG1063	alcohol dehydrogenase
D9C11_14775	COG2211	Major facilitator Superfamily
D9C11_14780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9C11_14790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C11_14800	COG4260	virion core protein, lumpy skin disease virus
D9C11_14810	COG2814	Major facilitator Superfamily
D9C11_14820	COG1063	alcohol dehydrogenase
D9C11_14825	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9C11_14830	COG0823	Involved in the tonB-independent uptake of proteins
D9C11_14845	COG2267	carboxylic ester hydrolase activity
D9C11_14855	COG2132	Multicopper oxidase
D9C11_14870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9C11_14875	COG0714	Associated with various cellular activities
D9C11_14880	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9C11_14885	COG1305	Transglutaminase-like
D9C11_14890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9C11_14890	COG0519	Catalyzes the synthesis of GMP from XMP
D9C11_14950	COG2252	PERMEase
D9C11_14955	COG3064	Membrane
D9C11_14970	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9C11_14980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9C11_14985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9C11_14990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9C11_14995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9C11_15000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C11_15005	COG0047	phosphoribosylformylglycinamidine synthase activity
D9C11_15010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9C11_15015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9C11_15020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9C11_15025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9C11_15030	COG0138	bifunctional purine biosynthesis protein purh
D9C11_15035	COG0151	Belongs to the GarS family
D9C11_15040	COG1522	sequence-specific DNA binding
D9C11_15045	COG0531	amino acid
D9C11_15055	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C11_15060	COG1470	cell adhesion involved in biofilm formation
D9C11_15065	COG4496	protein, YerC YecD
D9C11_15075	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9C11_15080	COG0210	DNA helicase
D9C11_15085	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9C11_15090	COG4851	CamS sex pheromone cAM373 precursor
D9C11_15095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9C11_15100	COG1285	pathogenesis
D9C11_15105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C11_15110	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C11_15115	COG0154	amidase activity
D9C11_15120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9C11_15125	COG1309	transcriptional regulator
D9C11_15130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9C11_15135	COG1597	lipid kinase activity
D9C11_15140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C11_15205	COG5444	nuclease activity
D9C11_15215	COG0457	Tetratricopeptide repeat
D9C11_15225	COG0217	transcriptional regulatory protein
D9C11_15235	COG1309	transcriptional regulator
D9C11_15250	COG3546	catalase activity
D9C11_15255	COG0454	-acetyltransferase
D9C11_15265	COG5578	integral membrane protein
D9C11_15270	COG2972	Histidine kinase
D9C11_15280	COG1653	transport
D9C11_15285	COG1175	transmembrane transport
D9C11_15300	COG3401	FG-GAP repeat protein
D9C11_15305	COG2755	lipolytic protein G-D-S-L family
D9C11_15310	COG1874	Beta-galactosidase
D9C11_15320	COG1653	transport
D9C11_15330	COG0395	ABC-type sugar transport system, permease component
D9C11_15340	COG2323	membrane
D9C11_15350	COG2329	Antibiotic biosynthesis monooxygenase
D9C11_15370	COG5583	Uncharacterized small protein (DUF2292)
D9C11_15375	COG0670	Belongs to the BI1 family
D9C11_15380	COG0697	spore germination
D9C11_15385	COG1846	Transcriptional regulator
D9C11_15405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9C11_15405	COG2124	cytochrome p450
D9C11_15410	COG1368	sulfuric ester hydrolase activity
D9C11_15415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9C11_15420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9C11_15430	COG1216	Glycosyl transferase, family 2
D9C11_15435	COG1442	glycosyl transferase family 8
D9C11_15440	COG2223	nitrite transmembrane transporter activity
D9C11_15445	COG1011	Hydrolase
D9C11_15450	COG0531	amino acid
D9C11_15455	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_15460	COG0840	transmembrane signaling receptor activity
D9C11_15465	COG0488	(ABC) transporter
D9C11_15475	COG0789	Transcriptional regulator
D9C11_15480	COG2814	Major facilitator Superfamily
D9C11_15495	COG0488	(ABC) transporter
D9C11_15500	COG0513	Belongs to the DEAD box helicase family
D9C11_15510	COG3866	Pectate lyase
D9C11_15515	COG0471	metal ion transport
D9C11_15520	COG3290	protein histidine kinase activity
D9C11_15525	COG4565	transcriptional regulatory protein
D9C11_15530	COG3181	Tripartite tricarboxylate transporter family receptor
D9C11_15535	COG2851	Citrate transporter
D9C11_15540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C11_15545	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9C11_15550	COG1254	Belongs to the acylphosphatase family
D9C11_15575	COG0024	Methionine aminopeptidase
D9C11_15580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_15580	COG1263	PTS System
D9C11_15585	COG1368	sulfuric ester hydrolase activity
D9C11_15610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_15610	COG1263	PTS System
D9C11_15610	COG1263	PTS System
D9C11_15610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_15615	COG0366	Alpha amylase catalytic
D9C11_15620	COG2188	Transcriptional regulator
D9C11_15625	COG0778	Nitroreductase
D9C11_15630	COG0737	Belongs to the 5'-nucleotidase family
D9C11_15635	COG0693	protein deglycase activity
D9C11_15640	COG2814	Major facilitator Superfamily
D9C11_15645	COG4840	Belongs to the UPF0435 family
D9C11_15650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9C11_15655	COG4980	gas vesicle protein
D9C11_15660	COG1295	ribonuclease BN
D9C11_15670	COG0477	Major facilitator Superfamily
D9C11_15675	COG0387	Pfam Sodium calcium exchanger
D9C11_15685	COG0668	transmembrane transport
D9C11_15690	COG0535	radical SAM domain protein
D9C11_15700	COG0726	polysaccharide deacetylase
D9C11_15705	COG2084	Dehydrogenase
D9C11_15710	COG0598	Magnesium transport protein CorA
D9C11_15715	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9C11_15720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9C11_15750	COG1131	(ABC) transporter
D9C11_15760	COG1131	(ABC) transporter
D9C11_15765	COG1668	transmembrane transport
D9C11_15775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9C11_15780	COG4637	Psort location Cytoplasmic, score
D9C11_15790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C11_15795	COG0022	dehydrogenase e1 component
D9C11_15800	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C11_15805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C11_15810	COG3284	Transcriptional regulator
D9C11_15820	COG1742	UPF0060 membrane protein
D9C11_15840	COG4842	Belongs to the WXG100 family
D9C11_15845	COG1486	melibiose metabolic process
D9C11_15850	COG1737	Transcriptional regulator
D9C11_15855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_15855	COG1263	PTS System
D9C11_15860	COG1132	(ABC) transporter
D9C11_15865	COG1132	(ABC) transporter
D9C11_15870	COG2259	Doxx family
D9C11_15875	COG2514	catechol 2,3-dioxygenase activity
D9C11_15880	COG4585	Histidine kinase
D9C11_15885	COG2197	response regulator
D9C11_15890	COG1131	(ABC) transporter
D9C11_15895	COG1511	domain protein
D9C11_15895	COG0842	Transport permease protein
D9C11_15900	COG0842	Transport permease protein
D9C11_15910	COG1695	Transcriptional regulator
D9C11_15915	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9C11_15920	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9C11_15925	COG1309	transcriptional regulator
D9C11_15930	COG2814	Major facilitator Superfamily
D9C11_15935	COG2318	DinB family
D9C11_15940	COG2814	Major facilitator Superfamily
D9C11_15945	COG1846	Transcriptional regulator
D9C11_15950	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9C11_15950	COG0392	lysyltransferase activity
D9C11_15955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9C11_15960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C11_15965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9C11_15970	COG0384	phenazine biosynthesis protein PhzF
D9C11_15975	COG0778	Nitroreductase
D9C11_15990	COG1090	epimerase
D9C11_15995	COG2137	regulation of response to DNA damage stimulus
D9C11_16005	COG2814	Major facilitator Superfamily
D9C11_16020	COG3103	Sh3 type 3 domain protein
D9C11_16025	COG5658	integral membrane protein
D9C11_16030	COG0596	Alpha beta hydrolase
D9C11_16035	COG0463	Glycosyl transferase, family 2
D9C11_16040	COG4485	Bacterial membrane protein, YfhO
D9C11_16045	COG1988	membrane-bound metal-dependent
D9C11_16050	COG1194	a g-specific adenine glycosylase
D9C11_16060	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_16075	COG3557	Belongs to the UPF0374 family
D9C11_16080	COG1132	(ABC) transporter
D9C11_16085	COG4129	membrane
D9C11_16090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9C11_16095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9C11_16100	COG0735	belongs to the Fur family
D9C11_16215	COG4326	sporulation control protein
D9C11_16225	COG5577	PFAM Coat F domain
D9C11_16230	COG3340	Belongs to the peptidase S51 family
D9C11_16235	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9C11_16250	COG0753	catalase activity
D9C11_16255	COG1116	anion transmembrane transporter activity
D9C11_16260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9C11_16265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9C11_16280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9C11_16290	COG1476	TRANSCRIPTIONal
D9C11_16300	COG3382	B3 4 domain protein
D9C11_16305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9C11_16315	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9C11_16320	COG0789	Transcriptional regulator
D9C11_16325	COG1664	Polymer-forming cytoskeletal
D9C11_16330	COG1664	Polymer-forming cytoskeletal
D9C11_16335	COG2766	serine protein kinase
D9C11_16340	COG2718	Belongs to the UPF0229 family
D9C11_16350	COG1566	PFAM secretion protein HlyD family protein
D9C11_16355	COG2814	Major facilitator Superfamily
D9C11_16360	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9C11_16380	COG1725	Transcriptional regulator
D9C11_16385	COG1131	(ABC) transporter
D9C11_16390	COG1131	(ABC) transporter
D9C11_16395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9C11_16400	COG1278	Cold shock
D9C11_16410	COG1464	Belongs to the NlpA lipoprotein family
D9C11_16420	COG1823	symporter activity
D9C11_16425	COG0582	viral genome integration into host DNA
D9C11_16430	COG2856	Zn peptidase
D9C11_16435	COG1396	sequence-specific DNA binding
D9C11_16470	COG1674	ftsk spoiiie
D9C11_16475	COG2946	Replication initiation factor
D9C11_16510	COG0433	COG0433 Predicted ATPase
D9C11_16520	COG5644	endopeptidase inhibitor activity
D9C11_16525	COG0741	lytic transglycosylase activity
D9C11_16525	COG0791	NLP P60 protein
D9C11_16540	COG0457	Tetratricopeptide repeat
D9C11_16565	COG1525	nuclease
D9C11_16565	COG0737	Belongs to the 5'-nucleotidase family
D9C11_16565	COG4085	toxin activity
D9C11_16570	COG3764	Sortase (surface protein transpeptidase)
D9C11_16575	COG0564	pseudouridine synthase activity
D9C11_16585	COG0517	IMP dehydrogenase activity
D9C11_16590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9C11_16595	COG3153	acetyltransferase
D9C11_16595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C11_16605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C11_16610	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9C11_16615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9C11_16620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9C11_16625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9C11_16630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9C11_16635	COG2203	Gaf domain
D9C11_16635	COG4585	Histidine kinase
D9C11_16640	COG2197	response regulator
D9C11_16645	COG0431	NADPH-dependent FMN reductase
D9C11_16665	COG1388	LysM domain
D9C11_16665	COG0791	NLP P60 protein
D9C11_16670	COG1959	2 iron, 2 sulfur cluster binding
D9C11_16675	COG0668	transmembrane transport
D9C11_16680	COG2719	SpoVR family
D9C11_16685	COG1785	Belongs to the alkaline phosphatase family
D9C11_16690	COG1388	LysM domain
D9C11_16690	COG0791	NLP P60 protein
D9C11_16695	COG0583	DNA-binding transcription factor activity
D9C11_16700	COG0372	Belongs to the citrate synthase family
D9C11_16710	COG0531	amino acid
D9C11_16715	COG0733	neurotransmitter:sodium symporter activity
D9C11_16720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_16725	COG0456	acetyltransferase
D9C11_16745	COG1595	DNA-templated transcription, initiation
D9C11_16750	COG0667	Aldo Keto reductase
D9C11_16755	COG0204	Acyl-transferase
D9C11_16765	COG1253	flavin adenine dinucleotide binding
D9C11_16770	COG0789	Transcriptional regulator
D9C11_16780	COG3344	reverse transcriptase
D9C11_16795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C11_16800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9C11_16805	COG0584	glycerophosphoryl diester phosphodiesterase
D9C11_16815	COG0668	transmembrane transport
D9C11_16820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9C11_16825	COG0726	polysaccharide deacetylase
D9C11_16830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9C11_16835	COG1757	Na H antiporter
D9C11_16840	COG0589	response to stress
D9C11_16850	COG1132	(ABC) transporter
D9C11_16855	COG1132	(ABC) transporter
D9C11_16860	COG0702	epimerase
D9C11_16880	COG0189	ligase activity
D9C11_16885	COG0189	ligase activity
D9C11_16890	COG4399	Belongs to the UPF0754 family
D9C11_16895	COG3679	Belongs to the UPF0342 family
D9C11_16905	COG0561	phosphatase activity
D9C11_16910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9C11_16915	COG0475	glutathione-regulated potassium exporter activity
D9C11_16920	COG0490	domain, Protein
D9C11_16930	COG1024	Enoyl-CoA hydratase
D9C11_16940	COG4152	abc transporter atp-binding protein
D9C11_16945	COG1668	transmembrane transport
D9C11_16950	COG0420	3'-5' exonuclease activity
D9C11_16955	COG4717	serine-type aminopeptidase activity
D9C11_16960	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9C11_16970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9C11_17000	COG1846	Transcriptional regulator
D9C11_17005	COG4980	gas vesicle protein
D9C11_17020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9C11_17025	COG0537	adenosine 5'-monophosphoramidase activity
D9C11_17030	COG1131	(ABC) transporter
D9C11_17035	COG4473	ABC transporter
D9C11_17045	COG1473	amidohydrolase
D9C11_17075	COG2329	Antibiotic biosynthesis monooxygenase
D9C11_17080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9C11_17085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9C11_17100	COG1309	transcriptional regulator
D9C11_17105	COG1511	domain protein
D9C11_17110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C11_17115	COG4377	Putative membrane peptidase family (DUF2324)
D9C11_17125	COG1363	Peptidase, m42
D9C11_17130	COG4405	Protein conserved in bacteria
D9C11_17135	COG1301	dicarboxylic acid transport
D9C11_17145	COG1234	tRNA 3'-trailer cleavage
D9C11_17150	COG0095	Lipoate-protein ligase
D9C11_17155	COG0702	epimerase
D9C11_17160	COG0318	PFAM AMP-dependent synthetase and ligase
D9C11_17170	COG0501	Belongs to the peptidase M48B family
D9C11_17175	COG1404	Belongs to the peptidase S8 family
D9C11_17180	COG0456	acetyltransferase
D9C11_17185	COG0604	alcohol dehydrogenase
D9C11_17190	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9C11_17195	COG0406	alpha-ribazole phosphatase activity
D9C11_17200	COG0183	Belongs to the thiolase family
D9C11_17205	COG0318	PFAM AMP-dependent synthetase and ligase
D9C11_17210	COG1268	BioY protein
D9C11_17215	COG0840	transmembrane signaling receptor activity
D9C11_17225	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_17235	COG4903	ComK protein
D9C11_17240	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_17250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C11_17265	COG0398	Pfam SNARE associated Golgi protein
D9C11_17270	COG0681	Belongs to the peptidase S26 family
D9C11_17280	COG1846	Transcriptional regulator
D9C11_17285	COG3180	Ammonia monooxygenase
D9C11_17290	COG0477	Major facilitator Superfamily
D9C11_17290	COG2814	Major facilitator Superfamily
D9C11_17295	COG4533	DNA binding
D9C11_17315	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9C11_17320	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9C11_17325	COG1074	ATP-dependent DNA helicase activity
D9C11_17330	COG0420	3'-5' exonuclease activity
D9C11_17335	COG0419	ATPase involved in DNA repair
D9C11_17340	COG1403	HNH endonuclease
D9C11_17380	COG5337	Spore coat protein CotH
D9C11_17395	COG1404	Belongs to the peptidase S8 family
D9C11_17405	COG0367	asparagine synthase
D9C11_17410	COG1562	ergosterol biosynthetic process
D9C11_17415	COG0534	Mate efflux family protein
D9C11_17420	COG1917	Cupin 2, conserved barrel domain protein
D9C11_17420	COG2207	Transcriptional regulator
D9C11_17425	COG1609	Transcriptional regulator
D9C11_17430	COG0673	inositol 2-dehydrogenase activity
D9C11_17435	COG2318	DinB family
D9C11_17440	COG1279	arginine transmembrane transporter activity
D9C11_17445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9C11_17450	COG1357	PFAM Pentapeptide repeats (8 copies)
D9C11_17455	COG2267	carboxylic ester hydrolase activity
D9C11_17465	COG2046	Belongs to the sulfate adenylyltransferase family
D9C11_17470	COG0175	sulfate reduction
D9C11_17475	COG2045	Belongs to the ComB family
D9C11_17480	COG1809	phosphosulfolactate synthase activity
D9C11_17485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C11_17510	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_17550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C11_17565	COG2323	membrane
D9C11_17575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C11_17580	COG2323	membrane
D9C11_17590	COG0454	-acetyltransferase
D9C11_17595	COG2153	protein acetylation
D9C11_17600	COG0646	methionine synthase
D9C11_17600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9C11_17605	COG1666	GTP binding
D9C11_17610	COG2996	Protein conserved in bacteria
D9C11_17620	COG1307	EDD domain protein, DegV family
D9C11_17625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9C11_17640	COG0561	phosphatase activity
D9C11_17645	COG1073	alpha beta
D9C11_17650	COG2151	metal-sulfur cluster biosynthetic enzyme
D9C11_17660	COG0277	FAD linked oxidase domain protein
D9C11_17665	COG2271	Major facilitator Superfamily
D9C11_17670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9C11_17685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9C11_17690	COG0505	Belongs to the CarA family
D9C11_17695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C11_17700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9C11_17715	COG2267	carboxylic ester hydrolase activity
D9C11_17725	COG1744	ABC transporter substrate-binding protein PnrA-like
D9C11_17740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C11_17745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9C11_17750	COG5504	Zn-dependent protease
D9C11_17755	COG0444	Belongs to the ABC transporter superfamily
D9C11_17760	COG4608	Belongs to the ABC transporter superfamily
D9C11_17770	COG0601	transmembrane transport
D9C11_17775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C11_17785	COG0180	Tryptophanyl-tRNA synthetase
D9C11_17790	COG4166	transmembrane transport
D9C11_17795	COG0601	transmembrane transport
D9C11_17800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C11_17805	COG0444	Belongs to the ABC transporter superfamily
D9C11_17810	COG4608	Belongs to the ABC transporter superfamily
D9C11_17815	COG2814	Major facilitator Superfamily
D9C11_17820	COG0456	acetyltransferase
D9C11_17825	COG1393	Belongs to the ArsC family
D9C11_17830	COG0861	Integral membrane protein TerC family
D9C11_17840	COG4862	establishment of competence for transformation
D9C11_17850	COG4469	Competence protein
D9C11_17855	COG1164	Oligoendopeptidase f
D9C11_17875	COG2346	COG2346, Truncated hemoglobins
D9C11_17880	COG0741	lytic transglycosylase activity
D9C11_17885	COG4116	CYTH
D9C11_17895	COG2357	RelA SpoT domain protein
D9C11_17900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9C11_17905	COG0564	pseudouridine synthase activity
D9C11_17910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9C11_17915	COG0569	domain protein
D9C11_17915	COG0475	glutathione-regulated potassium exporter activity
D9C11_17920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9C11_17930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9C11_17935	COG2104	thiamine diphosphate biosynthetic process
D9C11_17940	COG2022	thiamine diphosphate biosynthetic process
D9C11_17945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C11_17950	COG0351	phosphomethylpyrimidine kinase
D9C11_17955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9C11_18010	COG0210	DNA helicase
D9C11_18020	COG2153	protein acetylation
D9C11_18025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9C11_18030	COG2382	esterase
D9C11_18035	COG0626	cystathionine gamma-synthase activity
D9C11_18040	COG0626	cystathionine gamma-synthase activity
D9C11_18045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_18050	COG5505	Protein of unknown function (DUF819)
D9C11_18060	COG4974	Belongs to the 'phage' integrase family
D9C11_18065	COG2856	Zn peptidase
D9C11_18080	COG1396	sequence-specific DNA binding
D9C11_18125	COG5377	YqaJ viral recombinase family
D9C11_18130	COG3723	Recombinational DNA repair protein, rece pathway
D9C11_18135	COG3935	DnaD domain protein
D9C11_18140	COG1484	DNA-dependent DNA replication
D9C11_18200	COG3677	Transposase
D9C11_18215	COG5484	DNA packaging
D9C11_18220	COG1783	phage Terminase large subunit
D9C11_18360	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_18360	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_18370	COG5444	nuclease activity
D9C11_18400	COG0582	viral genome integration into host DNA
D9C11_18425	COG3328	transposase activity
D9C11_18435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_18445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9C11_18465	COG0109	protoheme IX farnesyltransferase activity
D9C11_18475	COG0726	polysaccharide deacetylase
D9C11_18515	COG1051	belongs to the nudix hydrolase family
D9C11_18525	COG2124	cytochrome p450
D9C11_18530	COG1819	glycosyl
D9C11_18540	COG1587	Uroporphyrinogen-III synthase
D9C11_18545	COG0390	transport system, permease component
D9C11_18550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9C11_18555	COG0697	spore germination
D9C11_18560	COG4297	protein containing double-stranded beta helix domain
D9C11_18570	COG1252	NADH dehydrogenase
D9C11_18575	COG1904	glucuronate isomerase
D9C11_18580	COG2211	Major facilitator Superfamily
D9C11_18585	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9C11_18600	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_18610	COG1609	Transcriptional regulator
D9C11_18615	COG0246	Mannitol dehydrogenase
D9C11_18625	COG0730	response to heat
D9C11_18635	COG2318	DinB family
D9C11_18645	COG0457	Tetratricopeptide repeat
D9C11_18655	COG2350	Protein conserved in bacteria
D9C11_18660	COG1388	LysM domain
D9C11_18660	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_18660	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_18670	COG4195	phage-related replication protein
D9C11_18680	COG2856	Zn peptidase
D9C11_18685	COG1396	sequence-specific DNA binding
D9C11_18695	COG1522	sequence-specific DNA binding
D9C11_18700	COG1484	DNA-dependent DNA replication
D9C11_18720	COG1595	DNA-templated transcription, initiation
D9C11_18725	COG3728	DNA packaging
D9C11_18725	COG5484	DNA packaging
D9C11_18730	COG1783	phage Terminase large subunit
D9C11_18735	COG5518	Phage portal protein
D9C11_18740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9C11_18745	COG4653	Phage capsid family
D9C11_18795	COG5412	phage tail tape measure protein
D9C11_18795	COG3953	SLT domain
D9C11_18800	COG1652	LysM domain
D9C11_18805	COG4193	domain, Protein
D9C11_18815	COG3628	GPW Gp25 family protein
D9C11_18820	COG3299	homolog of phage Mu protein gp47
D9C11_18825	COG3778	Protein conserved in bacteria
D9C11_18865	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_18865	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_18885	COG0306	phosphate transporter
D9C11_18890	COG1392	Phosphate transport regulator
D9C11_18895	COG0531	amino acid
D9C11_18905	COG0346	lactoylglutathione lyase activity
D9C11_18915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9C11_18920	COG0463	Glycosyl transferase, family 2
D9C11_18925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9C11_18930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C11_18935	COG2362	D-Aminopeptidase
D9C11_18940	COG0601	transmembrane transport
D9C11_18945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9C11_18950	COG0444	Belongs to the ABC transporter superfamily
D9C11_18955	COG4166	transmembrane transport
D9C11_18960	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C11_18965	COG4948	Mandelate Racemase Muconate Lactonizing
D9C11_18970	COG0791	NLP P60 protein
D9C11_18975	COG4608	Belongs to the ABC transporter superfamily
D9C11_18980	COG2706	6-phosphogluconolactonase activity
D9C11_18990	COG1607	acyl-coa hydrolase
D9C11_18995	COG1017	nitric oxide dioxygenase activity
D9C11_18995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9C11_19005	COG2323	membrane
D9C11_19010	COG2318	DinB family
D9C11_19015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_19020	COG2076	Multidrug Resistance protein
D9C11_19025	COG2076	Multidrug Resistance protein
D9C11_19030	COG0788	formyltetrahydrofolate deformylase activity
D9C11_19035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C11_19040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9C11_19045	COG1764	response to oxidative stress
D9C11_19050	COG1846	Transcriptional regulator
D9C11_19055	COG1764	response to oxidative stress
D9C11_19065	COG0590	tRNA wobble adenosine to inosine editing
D9C11_19075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9C11_19080	COG1404	Belongs to the peptidase S8 family
D9C11_19085	COG1366	Belongs to the anti-sigma-factor antagonist family
D9C11_19090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9C11_19095	COG1122	ATPase activity
D9C11_19100	COG4721	ABC-type cobalt transport system, permease component
D9C11_19110	COG0745	RESPONSE REGULATOR receiver
D9C11_19125	COG3212	peptidase
D9C11_19140	COG2239	Acts as a magnesium transporter
D9C11_19145	COG0789	Transcriptional regulator
D9C11_19160	COG1846	Transcriptional regulator
D9C11_19170	COG0726	polysaccharide deacetylase
D9C11_19175	COG1408	metallophosphoesterase
D9C11_19185	COG0463	Glycosyl transferase, family 2
D9C11_19190	COG1793	dna ligase
D9C11_19190	COG3285	dna ligase
D9C11_19195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9C11_19205	COG0586	Pfam SNARE associated Golgi protein
D9C11_19210	COG0861	Integral membrane protein TerC family
D9C11_19215	COG1191	sigma factor activity
D9C11_19235	COG0501	Belongs to the peptidase M48B family
D9C11_19240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9C11_19255	COG3594	Acyltransferase
D9C11_19260	COG5002	protein histidine kinase activity
D9C11_19265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9C11_19280	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9C11_19285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9C11_19290	COG0436	Aminotransferase
D9C11_19295	COG1850	ribulose-bisphosphate carboxylase activity
D9C11_19300	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9C11_19305	COG0235	Class ii aldolase
D9C11_19310	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9C11_19315	COG3339	Conserved Protein
D9C11_19330	COG3852	Histidine kinase
D9C11_19335	COG1846	Transcriptional regulator
D9C11_19340	COG1360	Flagellar Motor Protein
D9C11_19345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9C11_19350	COG0542	response to heat
D9C11_19355	COG3949	Membrane
D9C11_19360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9C11_19365	COG0720	synthase
D9C11_19370	COG0602	queuosine metabolic process
D9C11_19375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9C11_19385	COG4873	Protein conserved in bacteria
D9C11_19395	COG3773	Cell wall hydrolase
D9C11_19400	COG2244	polysaccharide biosynthetic process
D9C11_19405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_19410	COG2217	Heavy metal translocating P-type atpase
D9C11_19420	COG0006	proline dipeptidase activity
D9C11_19425	COG1609	Transcriptional regulator
D9C11_19430	COG3711	transcriptional antiterminator
D9C11_19435	COG2190	(PTS) system
D9C11_19435	COG1263	PTS System
D9C11_19435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9C11_19440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C11_19445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9C11_19455	COG1533	DNA photolyase activity
D9C11_19460	COG0456	acetyltransferase
D9C11_19465	COG0840	transmembrane signaling receptor activity
D9C11_19470	COG2084	Dehydrogenase
D9C11_19475	COG4257	antibiotic catabolic process
D9C11_19480	COG3328	transposase activity
D9C11_19490	COG2340	Cysteine-rich secretory protein family
D9C11_19495	COG0768	penicillin binding
D9C11_19500	COG4191	Histidine kinase
D9C11_19505	COG0436	Aminotransferase
D9C11_19515	COG0835	chemotaxis
D9C11_19515	COG0784	Response regulator, receiver
D9C11_19525	COG2814	Major facilitator Superfamily
D9C11_19530	COG1376	ErfK ybiS ycfS ynhG family protein
D9C11_19535	COG1408	metallophosphoesterase
D9C11_19540	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_19560	COG2200	EAL domain
D9C11_19565	COG4703	Protein of unknown function (DUF1797)
D9C11_19570	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9C11_19580	COG0517	IMP dehydrogenase activity
D9C11_19585	COG0583	DNA-binding transcription factor activity
D9C11_19590	COG0716	FMN binding
D9C11_19600	COG0716	FMN binding
D9C11_19605	COG2171	N-acyltransferase activity
D9C11_19610	COG1473	amidohydrolase
D9C11_19620	COG0668	transmembrane transport
D9C11_19625	COG0450	alkyl hydroperoxide reductase
D9C11_19630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_19650	COG0746	molybdenum cofactor guanylyltransferase activity
D9C11_19655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9C11_19660	COG0303	'Molybdopterin
D9C11_19665	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9C11_19670	COG0314	molybdopterin synthase activity
D9C11_19675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9C11_19680	COG1132	(ABC) transporter
D9C11_19685	COG1132	(ABC) transporter
D9C11_19695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9C11_19700	COG1136	(ABC) transporter
D9C11_19705	COG0577	efflux transmembrane transporter activity
D9C11_19710	COG1349	DNA-binding transcription factor activity
D9C11_19715	COG1105	Belongs to the carbohydrate kinase PfkB family
D9C11_19720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9C11_19720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C11_19720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9C11_19725	COG0681	Belongs to the peptidase S26 family
D9C11_19735	COG0488	(ABC) transporter
D9C11_19755	COG2309	aminopeptidase activity
D9C11_19765	COG1077	Cell shape determining protein MreB Mrl
D9C11_19770	COG2002	toxin-antitoxin pair type II binding
D9C11_19775	COG3852	Histidine kinase
D9C11_19780	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9C11_19780	COG2105	PFAM AIG2 family protein
D9C11_19785	COG0569	domain protein
D9C11_19790	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9C11_19795	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C11_19810	COG0242	peptide deformylase activity
D9C11_19820	COG0497	DNA recombination
D9C11_19825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9C11_19830	COG0022	dehydrogenase e1 component
D9C11_19835	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C11_19840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9C11_19845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_19855	COG1982	Orn Lys Arg decarboxylase major
D9C11_19860	COG4476	Belongs to the UPF0223 family
D9C11_19865	COG4493	Belongs to the UPF0637 family
D9C11_19875	COG0483	inositol monophosphate 1-phosphatase activity
D9C11_19910	COG1595	DNA-templated transcription, initiation
D9C11_19940	COG4896	Protein conserved in bacteria
D9C11_19955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9C11_19960	COG2066	Belongs to the glutaminase family
D9C11_19965	COG4838	Belongs to the UPF0358 family
D9C11_19970	COG0772	Belongs to the SEDS family
D9C11_19975	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9C11_19980	COG1612	heme a metabolic process
D9C11_19985	COG0109	protoheme IX farnesyltransferase activity
D9C11_19990	COG2010	Cytochrome c
D9C11_19990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9C11_19995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9C11_20000	COG1845	cytochrome c oxidase, subunit III
D9C11_20005	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9C11_20010	COG3336	cytochrome c oxidase
D9C11_20020	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9C11_20025	COG2340	Cysteine-rich secretory protein family
D9C11_20040	COG3679	Belongs to the UPF0342 family
D9C11_20045	COG4471	UPF0298 protein
D9C11_20050	COG0742	ribosomal rna small subunit methyltransferase
D9C11_20055	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9C11_20060	COG3314	Sporulation integral membrane protein YlbJ
D9C11_20065	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9C11_20070	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9C11_20085	COG1323	Belongs to the UPF0348 family
D9C11_20095	COG1399	metal-binding, possibly nucleic acid-binding protein
D9C11_20100	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9C11_20110	COG0454	-acetyltransferase
D9C11_20115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9C11_20120	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9C11_20125	COG2001	Belongs to the MraZ family
D9C11_20130	COG0275	rRNA processing
D9C11_20135	COG4839	cell division protein FtsL
D9C11_20145	COG0768	penicillin binding
D9C11_20150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9C11_20155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9C11_20160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9C11_20165	COG0772	Belongs to the SEDS family
D9C11_20170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9C11_20175	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9C11_20180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9C11_20185	COG3879	Bacterial protein of unknown function (DUF881)
D9C11_20190	COG3879	Bacterial protein of unknown function (DUF881)
D9C11_20195	COG3856	small basic protein
D9C11_20200	COG0849	cell division
D9C11_20205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9C11_20210	COG4412	M6 family metalloprotease domain protein
D9C11_20210	COG1404	Belongs to the peptidase S8 family
D9C11_20220	COG1191	sigma factor activity
D9C11_20225	COG1191	sigma factor activity
D9C11_20230	COG1119	ATPase activity
D9C11_20240	COG1873	PFAM PRC-barrel domain
D9C11_20250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9C11_20255	COG1799	cell septum assembly
D9C11_20260	COG0762	integral membrane protein
D9C11_20265	COG2302	S4 RNA-binding domain
D9C11_20270	COG3599	regulation of cell shape
D9C11_20275	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9C11_20280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C11_20285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9C11_20290	COG0564	pseudouridine synthase activity
D9C11_20295	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9C11_20300	COG2233	PERMEase
D9C11_20305	COG0540	Belongs to the ATCase OTCase family
D9C11_20310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9C11_20315	COG0505	Belongs to the CarA family
D9C11_20320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9C11_20325	COG0543	2 iron, 2 sulfur cluster binding
D9C11_20330	COG0167	dihydroorotate dehydrogenase activity
D9C11_20335	COG0284	orotidine-5'-phosphate decarboxylase activity
D9C11_20340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9C11_20345	COG0175	sulfate reduction
D9C11_20350	COG0306	phosphate transporter
D9C11_20355	COG2046	Belongs to the sulfate adenylyltransferase family
D9C11_20360	COG0529	Catalyzes the synthesis of activated sulfate
D9C11_20365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9C11_20370	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9C11_20375	COG1648	precorrin-2 dehydrogenase activity
D9C11_20385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9C11_20390	COG1561	YicC-like family, N-terminal region
D9C11_20395	COG2052	Domain of unknown function (DUF370)
D9C11_20400	COG0194	GDP metabolic process
D9C11_20405	COG1758	RNA polymerase activity
D9C11_20410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C11_20415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9C11_20420	COG0242	peptide deformylase activity
D9C11_20425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9C11_20430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9C11_20430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9C11_20435	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9C11_20440	COG0631	protein serine/threonine phosphatase activity
D9C11_20445	COG0515	serine threonine protein kinase
D9C11_20445	COG2815	serine threonine protein kinase
D9C11_20450	COG1162	GTPase activity
D9C11_20455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9C11_20460	COG1564	THIamine pyrophosphokinase
D9C11_20470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9C11_20475	COG1302	Protein conserved in bacteria
D9C11_20480	COG1461	Dihydroxyacetone kinase
D9C11_20485	COG1760	l-serine dehydratase
D9C11_20490	COG1760	l-serine dehydratase
D9C11_20495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9C11_20500	COG1349	DNA-binding transcription factor activity
D9C11_20500	COG2050	protein possibly involved in aromatic compounds catabolism
D9C11_20505	COG0416	fatty acid biosynthetic process
D9C11_20510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9C11_20515	COG1028	Short-chain dehydrogenase reductase Sdr
D9C11_20520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9C11_20525	COG0571	ribonuclease III activity
D9C11_20530	COG1196	nuclear chromosome segregation
D9C11_20535	COG0552	protein localization to endoplasmic reticulum
D9C11_20545	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9C11_20550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9C11_20555	COG0228	four-way junction DNA binding
D9C11_20560	COG1837	Belongs to the UPF0109 family
D9C11_20570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9C11_20575	COG0336	Belongs to the RNA methyltransferase TrmD family
D9C11_20580	COG0335	large ribosomal subunit rRNA binding
D9C11_20585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9C11_20590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9C11_20600	COG2257	FlhB HrpN YscU SpaS Family
D9C11_20605	COG0045	succinate-CoA ligase (ADP-forming) activity
D9C11_20610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9C11_20615	COG0758	DNA mediated transformation
D9C11_20620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9C11_20625	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9C11_20630	COG4974	Belongs to the 'phage' integrase family
D9C11_20635	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9C11_20640	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9C11_20645	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9C11_20650	COG1815	bacterial-type flagellum-dependent cell motility
D9C11_20655	COG1558	bacterial-type flagellum-dependent cell motility
D9C11_20660	COG1677	Flagellar hook-basal body complex protein FliE
D9C11_20665	COG1766	The M ring may be actively involved in energy transduction
D9C11_20670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C11_20675	COG1317	bacterial-type flagellum organization
D9C11_20680	COG1157	protein secretion by the type III secretion system
D9C11_20685	COG2882	bacterial-type flagellum organization
D9C11_20690	COG3334	PFAM MgtE intracellular
D9C11_20695	COG3144	bacterial-type flagellum assembly
D9C11_20700	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9C11_20705	COG4786	Flagellar basal body rod
D9C11_20710	COG1582	Flagellar protein (FlbD)
D9C11_20715	COG1580	Controls the rotational direction of flagella during chemotaxis
D9C11_20720	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C11_20725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9C11_20725	COG1776	CheC inhibitor of MCP methylation
D9C11_20730	COG2201	protein-glutamate methylesterase activity
D9C11_20735	COG3190	flagellar
D9C11_20740	COG1338	Plays a role in the flagellum-specific transport system
D9C11_20745	COG1987	bacterial-type flagellum assembly
D9C11_20750	COG1684	flagellar biosynthetic protein fliR
D9C11_20755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C11_20760	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9C11_20765	COG1419	protein localization to endoplasmic reticulum
D9C11_20770	COG0455	bacterial-type flagellum organization
D9C11_20775	COG2201	protein-glutamate methylesterase activity
D9C11_20780	COG2198	Histidine kinase
D9C11_20780	COG0643	Histidine kinase
D9C11_20785	COG0835	chemotaxis
D9C11_20790	COG1776	CheC inhibitor of MCP methylation
D9C11_20795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9C11_20800	COG1191	sigma factor activity
D9C11_20810	COG0052	Belongs to the universal ribosomal protein uS2 family
D9C11_20815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9C11_20820	COG0528	UMP kinase activity
D9C11_20825	COG0233	cytoplasmic translational termination
D9C11_20830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9C11_20835	COG4589	Belongs to the CDS family
D9C11_20840	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9C11_20845	COG0750	zinc metalloprotease
D9C11_20850	COG0442	prolyl-tRNA aminoacylation
D9C11_20855	COG2176	DNA-directed DNA polymerase activity
D9C11_20860	COG0779	Required for maturation of 30S ribosomal subunits
D9C11_20865	COG0195	Participates in both transcription termination and antitermination
D9C11_20870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9C11_20875	COG1358	cellular component organization or biogenesis
D9C11_20880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9C11_20885	COG1550	Protein conserved in bacteria
D9C11_20890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9C11_20895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9C11_20900	COG0196	riboflavin kinase activity
D9C11_20905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9C11_20910	COG1185	polyribonucleotide nucleotidyltransferase activity
D9C11_20915	COG0726	polysaccharide deacetylase
D9C11_20920	COG0612	Peptidase, M16
D9C11_20925	COG1873	PFAM PRC-barrel domain
D9C11_20930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9C11_20935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9C11_20940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9C11_20945	COG0527	aspartate kinase activity
D9C11_20950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9C11_20955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9C11_20960	COG0740	serine-type endopeptidase activity
D9C11_20970	COG1674	ftsk spoiiie
D9C11_20970	COG4980	gas vesicle protein
D9C11_20975	COG2188	Transcriptional regulator
D9C11_20980	COG2814	Major facilitator Superfamily
D9C11_20985	COG0612	Peptidase, M16
D9C11_20990	COG0612	Peptidase, M16
D9C11_20995	COG0300	oxidoreductase activity
D9C11_21010	COG1426	Protein conserved in bacteria
D9C11_21015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9C11_21020	COG1546	Belongs to the CinA family
D9C11_21020	COG1058	Belongs to the CinA family
D9C11_21025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9C11_21030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9C11_21035	COG1418	mRNA catabolic process
D9C11_21040	COG1692	metallophosphoesterase
D9C11_21045	COG2359	stage V sporulation protein S
D9C11_21050	COG1063	alcohol dehydrogenase
D9C11_21055	COG0156	8-amino-7-oxononanoate synthase activity
D9C11_21060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9C11_21065	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9C11_21075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9C11_21080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9C11_21095	COG3226	Transcriptional regulator
D9C11_21105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C11_21110	COG1404	Belongs to the peptidase S8 family
D9C11_21120	COG4195	phage-related replication protein
D9C11_21125	COG1764	response to oxidative stress
D9C11_21130	COG2076	Multidrug Resistance protein
D9C11_21135	COG2076	Multidrug Resistance protein
D9C11_21150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9C11_21155	COG1923	regulation of RNA biosynthetic process
D9C11_21170	COG1780	Probably involved in ribonucleotide reductase function
D9C11_21175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C11_21180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9C11_21185	COG4112	unkown
D9C11_21190	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_21200	COG0464	growth
D9C11_21205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9C11_21210	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9C11_21215	COG0789	Transcriptional regulator
D9C11_21220	COG0174	glutamine synthetase
D9C11_21225	COG0582	viral genome integration into host DNA
D9C11_21235	COG3328	transposase activity
D9C11_21240	COG1525	nuclease
D9C11_21245	COG5444	nuclease activity
D9C11_21260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_21275	COG0457	Tetratricopeptide repeat
D9C11_21290	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_21305	COG2433	Pfam Transposase IS66
D9C11_21335	COG0582	viral genome integration into host DNA
D9C11_21460	COG0776	regulation of translation
D9C11_21515	COG0210	DNA helicase
D9C11_21610	COG3655	Transcriptional regulator
D9C11_21680	COG3645	SOS response
D9C11_21680	COG3646	Phage regulatory protein
D9C11_21735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_21740	COG0756	dUTP diphosphatase activity
D9C11_21845	COG3331	DNA recombination
D9C11_21855	COG1086	Polysaccharide biosynthesis protein
D9C11_21860	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D9C11_21865	COG4641	Protein conserved in bacteria
D9C11_21880	COG0456	acetyltransferase
D9C11_21900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9C11_21905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9C11_21915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9C11_21920	COG0456	acetyltransferase
D9C11_21925	COG1509	lysine 2,3-aminomutase activity
D9C11_21975	COG0756	dUTP diphosphatase activity
D9C11_22010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9C11_22025	COG3832	glyoxalase III activity
D9C11_22065	COG4195	phage-related replication protein
D9C11_22075	COG0346	lactoylglutathione lyase activity
D9C11_22085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9C11_22090	COG1388	LysM domain
D9C11_22095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9C11_22100	COG4224	UPF0291 protein
D9C11_22105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9C11_22115	COG3763	UPF0154 protein
D9C11_22125	COG0785	Cytochrome C biogenesis protein
D9C11_22130	COG2201	protein-glutamate methylesterase activity
D9C11_22135	COG4846	Membrane protein involved in cytochrome C biogenesis
D9C11_22145	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C11_22160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9C11_22165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9C11_22185	COG0824	Thioesterase
D9C11_22195	COG4841	protein insertion into membrane
D9C11_22200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9C11_22205	COG1832	CoA-binding protein
D9C11_22210	COG0187	DNA topoisomerase II activity
D9C11_22215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9C11_22225	COG1115	amino acid carrier protein
D9C11_22230	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9C11_22250	COG2246	polysaccharide biosynthetic process
D9C11_22255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9C11_22260	COG0586	Pfam SNARE associated Golgi protein
D9C11_22265	COG2404	hydrolase activity, acting on ester bonds
D9C11_22270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9C11_22275	COG1024	Enoyl-CoA hydratase
D9C11_22280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9C11_22285	COG0511	ligase activity, forming carbon-carbon bonds
D9C11_22290	COG0439	Biotin carboxylase
D9C11_22295	COG0318	PFAM AMP-dependent synthetase and ligase
D9C11_22300	COG1960	acyl-CoA dehydrogenase activity
D9C11_22335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9C11_22340	COG2027	D-alanyl-D-alanine carboxypeptidase
D9C11_22345	COG2017	converts alpha-aldose to the beta-anomer
D9C11_22350	COG0534	Mate efflux family protein
D9C11_22365	COG0582	viral genome integration into host DNA
D9C11_22370	COG0166	Belongs to the GPI family
D9C11_22375	COG0405	Gamma-glutamyltransferase
D9C11_22385	COG0493	'glutamate synthase
D9C11_22390	COG0070	glutamate synthase
D9C11_22390	COG0067	glutamate synthase
D9C11_22390	COG0069	glutamate synthase activity
D9C11_22395	COG0583	DNA-binding transcription factor activity
D9C11_22400	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9C11_22405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9C11_22415	COG0300	oxidoreductase activity
D9C11_22420	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9C11_22430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9C11_22445	COG1131	(ABC) transporter
D9C11_22455	COG2814	Major facilitator Superfamily
D9C11_22465	COG2323	membrane
D9C11_22470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9C11_22480	COG2323	membrane
D9C11_22495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9C11_22515	COG3546	catalase activity
D9C11_22535	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9C11_22550	COG0840	transmembrane signaling receptor activity
D9C11_22550	COG5278	phosphoserine phosphatase activity
D9C11_22555	COG2368	4-hydroxyphenylacetate
D9C11_22560	COG4305	rare lipoprotein A
D9C11_22565	COG3619	membrane
D9C11_22625	COG2720	vancomycin resistance protein
D9C11_22635	COG3655	Transcriptional regulator
D9C11_22685	COG5444	nuclease activity
D9C11_22690	COG4282	regulation of fungal-type cell wall biogenesis
D9C11_22695	COG1231	oxidoreductase activity
D9C11_22700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9C11_22705	COG2207	Transcriptional regulator
D9C11_22705	COG0662	Cupin 2, conserved barrel domain protein
D9C11_22710	COG0456	acetyltransferase
D9C11_22715	COG1309	transcriptional regulator
D9C11_22720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9C11_22725	COG3708	Transcriptional regulator
D9C11_22730	COG2378	regulation of single-species biofilm formation
D9C11_22740	COG0640	Transcriptional regulator
D9C11_22745	COG0741	lytic transglycosylase activity
D9C11_22750	COG2322	membrane
D9C11_22765	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9C11_22770	COG3239	Fatty acid desaturase
D9C11_22775	COG4585	Histidine kinase
D9C11_22780	COG2197	response regulator
D9C11_22785	COG3584	3D domain protein
D9C11_22785	COG1388	LysM domain
D9C11_22790	COG0514	ATP-dependent DNA helicase (RecQ)
D9C11_22805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9C11_22810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9C11_22825	COG0071	Belongs to the small heat shock protein (HSP20) family
D9C11_22850	COG1012	belongs to the aldehyde dehydrogenase family
D9C11_22860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9C11_22865	COG0733	neurotransmitter:sodium symporter activity
D9C11_22870	COG0385	Bile acid
D9C11_22875	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9C11_22880	COG0567	Dehydrogenase, E1 component
D9C11_22885	COG4548	von Willebrand factor, type A
D9C11_22890	COG0714	Associated with various cellular activities
D9C11_22895	COG2032	superoxide dismutase activity
D9C11_22900	COG1388	LysM domain
D9C11_22900	COG0791	NLP P60 protein
D9C11_22905	COG1819	glycosyl
D9C11_22910	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9C11_22915	COG0534	Mate efflux family protein
D9C11_22925	COG0457	Tetratricopeptide repeat
D9C11_22940	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9C11_22990	COG3953	SLT domain
D9C11_22990	COG5280	Phage tail tape measure protein TP901
D9C11_23030	COG0740	serine-type endopeptidase activity
D9C11_23080	COG1595	DNA-templated transcription, initiation
D9C11_23100	COG0305	Participates in initiation and elongation during chromosome replication
D9C11_23125	COG3646	Phage regulatory protein
D9C11_23125	COG3645	SOS response
D9C11_23165	COG0582	viral genome integration into host DNA
D9C11_23175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C11_23180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9C11_23190	COG2962	Rard protein
D9C11_23210	COG1942	4-Oxalocrotonate Tautomerase
D9C11_23215	COG1733	regulation of RNA biosynthetic process
D9C11_23220	COG0778	Nitroreductase
D9C11_23225	COG0400	carboxylic ester hydrolase activity
D9C11_23230	COG0346	lactoylglutathione lyase activity
D9C11_23240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9C11_23245	COG0793	Belongs to the peptidase S41A family
D9C11_23245	COG3409	Peptidoglycan-binding domain 1 protein
D9C11_23250	COG2226	methyltransferase
D9C11_23330	COG0582	viral genome integration into host DNA
D9C11_23375	COG1793	dna ligase
D9C11_23440	COG0741	lytic transglycosylase activity
D9C11_23440	COG0791	NLP P60 protein
D9C11_23545	COG1476	TRANSCRIPTIONal
D9C11_23555	COG4191	Histidine kinase
D9C11_23560	COG1073	alpha beta
D9C11_23580	COG2184	nucleotidyltransferase activity