locus-tag class description S100761_00001 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) S100761_00002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) S100761_00003 ENOG410848D S4 domain protein YaaA S100761_00006 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) S100761_00007 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) S100761_00014 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) S100761_00016 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) S100761_00017 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) S100761_00018 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) S100761_00020 ENOG4105ZMH deoxynucleoside kinase S100761_00022 ENOG4105VRS hydrolase family 18 S100761_00023 ENOG4105GTG Isochorismatase S100761_00024 ENOG4108Z6B deaminase S100761_00025 ENOG4105C6E dna polymerase iii S100761_00026 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) S100761_00027 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) S100761_00029 ENOG41067KS pro-sigma K processing S100761_00037 ENOG4105CDW Resistance protein S100761_00038 ENOG4105CXN decarboxylase S100761_00039 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) S100761_00040 ENOG4105X0R protein from nitrogen regulatory protein P-II S100761_00041 ENOG4105XVJ Protein of unknown function (DUF327) S100761_00042 ENOG4105FA2 dna polymerase iii S100761_00043 ENOG4105MA4 psp1 domain protein S100761_00044 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) S100761_00045 ENOG41060K3 Methyltransferase S100761_00046 ENOG4105VC4 domain protein S100761_00047 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) S100761_00048 ENOG4105KRN Transcriptional regulator, abrb family S100761_00049 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) S100761_00050 ENOG4105F8V Hydrolase, tatD family S100761_00051 ENOG41069ER domain protein S100761_00053 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) S100761_00054 ENOG4105XFA sporulation peptidase YabG S100761_00055 ENOG4105W42 Veg protein S100761_00056 ENOG4105XEW small acid-soluble spore protein S100761_00057 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) S100761_00058 ENOG4105DFT pur operon repressor S100761_00059 ENOG4105KME endoribonuclease L-psp S100761_00060 ENOG4105K4W Could be involved in septation (By similarity) S100761_00061 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) S100761_00062 ENOG4105C5T Phosphoribosyl pyrophosphate synthase S100761_00063 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) S100761_00064 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) S100761_00066 ENOG4108JA2 transcriptioN-repair coupling factor S100761_00067 ENOG4108M14 stage v sporulation protein t S100761_00069 ENOG4108IY2 MazG family S100761_00070 ENOG41082I2 s4 domain protein S100761_00071 ENOG4105VYY sporulation protein yabp S100761_00074 ENOG41060GV RNA binding s1 domain protein S100761_00080 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) S100761_00081 ENOG4108UGV hypoxanthine phosphoribosyltransferase S100761_00082 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) S100761_00084 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) S100761_00085 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase S100761_00086 ENOG4105C6T cysteine synthase S100761_00087 ENOG4105CRQ synthase (Component I) S100761_00088 ENOG4105DDQ anthranilate synthase S100761_00089 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 S100761_00090 ENOG4105EEI dihydropteroate synthase S100761_00091 ENOG4105KRF dihydroneopterin aldolase S100761_00092 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase S100761_00094 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) S100761_00095 ENOG4105CRK lysyL-tRNA synthetase S100761_00112 ENOG4108Z0C Uvrb UvrC protein S100761_00113 ENOG41066A3 ATP guanido phosphotransferase S100761_00115 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) S100761_00116 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) S100761_00117 ENOG4105CTP PilT protein domain protein S100761_00118 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) S100761_00119 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) S100761_00120 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) S100761_00121 ENOG4105D7W serine acetyltransferase S100761_00122 ENOG4105C8N cysteinyl-tRNA synthetase S100761_00123 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) S100761_00124 ENOG4105C2N RNA methyltransferase TrmH family group 3 S100761_00125 ENOG4105M0M Tetracycline resistance protein S100761_00128 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) S100761_00129 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) S100761_00131 ENOG4108VZM 50s ribosomal protein L10 S100761_00132 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) S100761_00133 ENOG4107Y49 methyltransferase S100761_00134 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) S100761_00135 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) S100761_00136 ENOG4105XPM ribosomal protein S100761_00137 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) S100761_00138 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) S100761_00139 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) S100761_00140 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) S100761_00141 ENOG4107SKW Inherit from COG: Alpha beta hydrolase S100761_00142 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) S100761_00143 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) S100761_00144 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) S100761_00145 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) S100761_00146 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity S100761_00147 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) S100761_00148 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) S100761_00149 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) S100761_00150 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) S100761_00151 ENOG41082SA 50s ribosomal protein l29 S100761_00152 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal S100761_00153 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) S100761_00155 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits S100761_00157 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) S100761_00158 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) S100761_00159 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) S100761_00160 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) S100761_00161 ENOG4105VPB 50S ribosomal protein L30 S100761_00162 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) S100761_00163 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) S100761_00165 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) S100761_00166 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) S100761_00168 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits S100761_00169 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) S100761_00170 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) S100761_00171 ENOG4108ZT0 50S ribosomal protein l17 S100761_00172 ENOG4108JJB ABC transporter S100761_00173 ENOG4108JJB ABC transporter S100761_00174 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) S100761_00175 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) S100761_00176 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) S100761_00177 ENOG4108UJD 30S ribosomal protein S9 S100761_00178 ENOG4108I0C methyltransferase S100761_00181 ENOG4105D1F ATP-binding protein S100761_00184 ENOG4108NMV polysaccharide deacetylase S100761_00200 ENOG4105CHH sulfate transporter S100761_00203 ENOG4108SA1 esterase S100761_00207 ENOG410874W AraC family transcriptional regulator S100761_00208 ENOG4105EHZ conserved protein UCP016719 S100761_00209 ENOG4105D17 glycoside hydrolase, family 3 domain protein S100761_00213 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate S100761_00215 ENOG4105EWC Purine nucleoside phosphorylase S100761_00221 ENOG4105EMN RNA polymerase sigma factor S100761_00223 ENOG4105C8B TIGR00159 family S100761_00224 ENOG4107U5W ybbr family S100761_00225 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) S100761_00226 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) S100761_00227 ENOG4105D03 DNA-3-methyladenine glycosylase II S100761_00229 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) S100761_00230 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) S100761_00231 ENOG4108TWJ NADH dehydrogenase subunit 5 S100761_00235 ENOG4105GPN Uncharacterized conserved protein (DUF2294) S100761_00236 ENOG4105WAB arsR family transcriptional regulator S100761_00237 ENOG4108RWP Major Facilitator Superfamily protein S100761_00243 ENOG4105G0J serine threonine protein kinase S100761_00245 ENOG4106K80 S100761_00247 ENOG4106DDH Sporulation-specific SASP protein S100761_00249 ENOG4108HWY Beta-lactamase S100761_00250 ENOG4107E6A Cytochrome p-450 S100761_00252 ENOG4107QTZ amino acid S100761_00253 ENOG4107VXM glycerophosphoryl diester phosphodiesterase S100761_00254 ENOG4105CXY transporter S100761_00256 ENOG410645S MarR family Transcriptional regulator S100761_00257 ENOG4105DCM major facilitator superfamily S100761_00258 ENOG410631K Membrane S100761_00259 ENOG4106AXJ AraC family transcriptional regulator S100761_00263 ENOG4105GIG S100761_00264 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR S100761_00265 ENOG4108TCS Glutamyl endopeptidase S100761_00267 ENOG4108WC5 Alpha Beta Hydrolase Fold protein S100761_00268 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase S100761_00269 ENOG4107ZTW SNARE associated Golgi S100761_00274 ENOG4105C72 UPF0176 protein S100761_00276 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane S100761_00277 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) S100761_00278 ENOG4108X79 transcriptional regulator S100761_00280 ENOG4105CM2 brancheD-chain amino acid aminotransferase S100761_00281 ENOG4108IQI permease S100761_00282 ENOG4108J5H Homocysteine s-methyltransferase S100761_00285 ENOG4105CSV Glutaminase S100761_00288 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase S100761_00289 ENOG4105C26 Dehydrogenase S100761_00290 ENOG4105DJB Major Facilitator Superfamily S100761_00291 ENOG4105EQX glucarate dehydratase S100761_00292 ENOG41073TP transcriptional regulator S100761_00293 ENOG4105CTX dehydratase S100761_00296 ENOG4106UX7 integral membrane protein S100761_00297 ENOG4105DPZ Two component transcriptional regulator (Winged helix family S100761_00303 ENOG4105MUA Resistance protein S100761_00304 ENOG4105DGI Alkaline phosphatase S100761_00305 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) S100761_00306 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) S100761_00307 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) S100761_00308 ENOG4107EPV Aminotransferase class V S100761_00309 ENOG4105C0R drug resistance transporter emrb qaca subfamily S100761_00310 ENOG4105J7D transcriptional regulator S100761_00311 ENOG4107RB3 L-asparaginase S100761_00312 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold S100761_00314 ENOG41060AI SEC-C motif S100761_00316 ENOG4107Y7X LytTR S100761_00317 ENOG4108IUW ABC transporter S100761_00318 ENOG4108SDH ABC, transporter S100761_00319 ENOG4107SET aldo keto reductase S100761_00325 ENOG4105H9W Short-chain dehydrogenase reductase Sdr S100761_00327 ENOG4105DSE periplasmic solute binding protein S100761_00328 ENOG4105DIK (ABC) transporter S100761_00330 ENOG4105DEN Luciferase family S100761_00331 ENOG4108N0M stress protein S100761_00332 ENOG4106FN3 tellurium resistance protein S100761_00333 ENOG4106FN3 tellurium resistance protein S100761_00334 ENOG4107TS3 membrane protein, TerC S100761_00335 ENOG4108TTB tellurium resistance protein S100761_00337 ENOG41079KZ Major Facilitator Superfamily S100761_00338 ENOG4107XZQ multidrug resistance protein S100761_00339 ENOG4108A65 Transcriptional regulator S100761_00340 ENOG4108IJ7 Glycine betaine S100761_00341 ENOG4107SQ8 Glycine betaine S100761_00347 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) S100761_00354 ENOG4105EIG urea carboxylase-associated protein 1 S100761_00355 ENOG4107RA1 nh(3)-dependent nad( ) synthetase S100761_00356 ENOG4105I1F Resistance protein S100761_00357 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) S100761_00358 ENOG41089UC methyltransferase, type 11 S100761_00359 ENOG4105C5Q Transcriptional regulator S100761_00360 ENOG4105I82 acetyl xylan esterase S100761_00361 ENOG410756H nucleotidyltransferase S100761_00363 ENOG4105C26 Dehydrogenase S100761_00364 ENOG4105CK7 Sodium proline symporter S100761_00365 ENOG4107YHD transcriptional regulator S100761_00367 ENOG4108PJD permease S100761_00368 ENOG4105U6C Alpha beta hydrolase fold protein S100761_00370 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) S100761_00371 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit S100761_00372 ENOG4108IFG nitrite reductase, (NAD(P)H) S100761_00373 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) S100761_00377 ENOG4105S7A ErfK ybiS ycfS ynhG family protein S100761_00378 ENOG4105CKI cobalamin synthesis protein S100761_00379 ENOG4105E5Q amino acid AbC transporter S100761_00380 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein S100761_00382 ENOG4105HHM rdd domain containing protein S100761_00384 ENOG4105K56 Transcriptional regulator S100761_00386 ENOG4108VEN abc transporter atp-binding protein S100761_00387 ENOG4105CS2 ec 3.2.1.21 S100761_00390 ENOG4105C8Q Methyl-accepting chemotaxis S100761_00391 ENOG41080HJ 6-phospho 3-hexuloisomerase S100761_00392 ENOG4108VA3 3-hexulose-6-phosphate synthase S100761_00393 ENOG4105KVH Transcriptional regulator S100761_00394 ENOG4105CEY Amp-dependent synthetase and ligase S100761_00400 ENOG4105SX7 Transporter S100761_00402 ENOG4105W8Z 4'-phosphopantetheinyl transferase S100761_00404 ENOG4105CDA abc transporter atp-binding protein S100761_00405 ENOG4105DRP amino acid AbC transporter S100761_00407 ENOG4106P55 Transcriptional regulator S100761_00408 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase S100761_00409 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) S100761_00410 ENOG41069ZX S100761_00411 ENOG41069ZX S100761_00413 ENOG4105DUX Transporter S100761_00416 ENOG4105E1K spore germination protein S100761_00420 ENOG4107WD8 ABC transporter, permease S100761_00421 ENOG4105CK6 Two component transcriptional regulator (Winged helix family S100761_00422 ENOG4105BZU Histidine kinase S100761_00426 ENOG4105CFH Aspartokinase S100761_00427 ENOG4105DHS permease protein S100761_00428 ENOG4105CM4 permease protein S100761_00429 ENOG4108IPW abc transporter atp-binding protein S100761_00433 ENOG4105R8C Transcriptional regulator S100761_00434 ENOG4108DBC nitroreductase S100761_00435 ENOG41067V3 Antibiotic biosynthesis monooxygenase S100761_00436 ENOG4105YVS arsR family transcriptional regulator S100761_00438 ENOG4108JPW Aminotransferase S100761_00439 ENOG4105C26 Dehydrogenase S100761_00441 ENOG4105H9W Short-chain dehydrogenase reductase Sdr S100761_00442 ENOG4105KTB nuclear export factor GLE1 S100761_00443 ENOG4108T5E Copper resistance protein S100761_00444 ENOG4108ZYE Transcriptional regulator S100761_00449 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) S100761_00451 ENOG4108ZX0 Signal peptidase I S100761_00456 ENOG4105E7W lamb ycsf family protein S100761_00457 ENOG4105C5A transporter S100761_00458 ENOG4105CFM UPF0317 protein S100761_00459 ENOG4105P4J Allophanate hydrolase, subunit 1 S100761_00461 ENOG4107258 Transcriptional regulator S100761_00462 ENOG4105XJB lipolytic protein G-D-S-L family S100761_00464 ENOG41061CK Antibiotic biosynthesis monooxygenase S100761_00465 ENOG4107RVG penicillin-binding protein S100761_00466 ENOG4107QM2 Aldo Keto reductase S100761_00467 ENOG4105ETD TRANSCRIPTIONal S100761_00469 ENOG4105HMZ Methyltransferase S100761_00470 ENOG4105CYX Short-chain dehydrogenase reductase Sdr S100761_00473 ENOG410606W general stress protein S100761_00475 ENOG4105VCH membrane S100761_00477 ENOG4105C9U ATP-dependent DNA helicase RecQ S100761_00480 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) S100761_00481 ENOG4107R8N Glycosyl transferase, family 2 S100761_00484 ENOG4105C0X amino acid S100761_00492 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) S100761_00494 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) S100761_00495 ENOG4105EU9 S100761_00496 ENOG4105QVS general stress protein S100761_00497 ENOG41082W1 Cupin 2, conserved barrel domain protein S100761_00500 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit S100761_00501 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism S100761_00502 ENOG4108MRH transcriptional regulatory protein S100761_00503 ENOG4107QJT sodium dicarboxylate symporter S100761_00504 ENOG4106F5Q Membrane S100761_00506 ENOG4105CJ1 ABC, transporter S100761_00509 ENOG4105FDT acyl-CoA dehydrogenase S100761_00513 ENOG4105SZ6 Thioredoxin S100761_00514 ENOG4105CPF Cell wall formation (By similarity) S100761_00515 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) S100761_00516 ENOG4105C1J atp-dependent rna helicase S100761_00517 ENOG410905X membrane-flanked domain protein S100761_00518 ENOG4105CKV Membrane S100761_00520 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) S100761_00521 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein S100761_00522 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) S100761_00524 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) S100761_00525 ENOG4107MMM Anti-sigma-factor antagonist S100761_00526 ENOG4105FUA antagonist S100761_00527 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase S100761_00528 ENOG4107SGM protein serine threonine phosphatase S100761_00529 ENOG4105WN5 stage II sporulation protein S100761_00530 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) S100761_00532 ENOG41064BQ Phosphatase S100761_00544 ENOG41085FC arsR family transcriptional regulator S100761_00545 ENOG41082YX Transcriptional regulator, arsr family S100761_00546 ENOG4107R5R arsenical pump membrane protein S100761_00547 ENOG4108UXE Protein tyrosine phosphatase S100761_00548 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) S100761_00549 ENOG41068WC Domain of unknown function (DUF955) S100761_00550 ENOG4108IMY Transcriptional regulator S100761_00554 ENOG4108RYM conjugative transposon protein S100761_00555 ENOG4106BHR ftsk SpoIIIE family protein S100761_00556 ENOG4106128 DNA-binding helix-turn-helix protein S100761_00564 ENOG4105P1M Domain of unknown function (DUF1874) S100761_00566 ENOG4105K4H Nlp p60 protein S100761_00573 ENOG4107V2S Transcriptional regulator S100761_00576 ENOG4106BHF S100761_00577 ENOG4105VZ8 Transcriptional regulator S100761_00582 ENOG4108V4B ThiJ pfpI S100761_00583 ENOG4105VEQ Cold shock protein S100761_00584 ENOG4108VJ1 Transcriptional regulator (CarD family S100761_00586 ENOG4108MCI Transcriptional regulator, ARAC family S100761_00587 ENOG4108UZ3 Transporter S100761_00588 ENOG41086D8 Transcriptional regulator S100761_00589 ENOG4107U9B transcriptional regulator S100761_00590 ENOG4105DXI Major Facilitator superfamily S100761_00591 ENOG4105DXI Major Facilitator superfamily S100761_00593 ENOG4105CZ9 Domain of unknown function (DU1801) S100761_00594 ENOG4105GIG S100761_00596 ENOG4105KRI phosphocarrier protein (HPr S100761_00597 ENOG4105ST3 Transcriptional regulator S100761_00598 ENOG4105T38 integral membrane protein S100761_00599 ENOG4105T38 integral membrane protein S100761_00600 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family S100761_00601 ENOG4108ZMQ domain protein S100761_00602 ENOG4105MJ9 esterase S100761_00603 ENOG4107Z6X Transcriptional regulator S100761_00605 ENOG4105KVH Transcriptional regulator S100761_00606 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein S100761_00607 ENOG4105EQ0 Major Facilitator superfamily S100761_00608 ENOG4108JGH Tetr family transcriptional regulator S100761_00609 ENOG41082YX Transcriptional regulator, arsr family S100761_00610 ENOG4107R5R arsenical pump membrane protein S100761_00611 ENOG4105Z7P Acetyltransferase (GNAT) family S100761_00612 ENOG4107Y9U Membrane S100761_00614 ENOG4105DY8 decarboxylase S100761_00615 ENOG4108SQ9 flavin reductase domain protein, FMN-binding S100761_00616 ENOG4108ZHR arsR family transcriptional regulator S100761_00617 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) S100761_00619 ENOG4105ENE Histidine kinase S100761_00620 ENOG4108VB1 regulatoR S100761_00621 ENOG4105EYF MMPL domain protein S100761_00622 ENOG4108UQV Membrane S100761_00623 ENOG4108Z5V transcriptional regulator, merr family S100761_00624 ENOG41076HS cation diffusion facilitator family transporter S100761_00625 ENOG4108TVJ Nitroreductase S100761_00626 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase S100761_00627 ENOG4108VGI doxx family S100761_00628 ENOG4105XXY Thioredoxin S100761_00632 ENOG410900G Protein of unknown function (DUF421) S100761_00633 ENOG4108QY0 Membrane S100761_00637 ENOG4105PF9 Transcriptional regulator S100761_00639 ENOG4105WQG acetyltransferase S100761_00641 ENOG4105C85 amino acid S100761_00643 ENOG41062A4 Transcriptional regulator S100761_00644 ENOG4105EYF MMPL domain protein S100761_00645 ENOG4108TVJ Nitroreductase S100761_00646 ENOG4105FS7 Transcriptional regulator S100761_00647 ENOG4105C2C drug resistance transporter, Bcr CflA S100761_00649 ENOG4105DRR Transcriptional regulator, GntR family S100761_00650 ENOG4105VRS hydrolase family 18 S100761_00653 ENOG4105G6Z alkaline phosphatase S100761_00654 ENOG4108ZMX Domain of unknown function (DU1801) S100761_00656 ENOG4108YM7 Gcn5-related n-acetyltransferase S100761_00657 ENOG4107TVP HD domain protein S100761_00658 ENOG41090UD (LipO)protein S100761_00659 ENOG4105F27 Major Facilitator S100761_00660 ENOG4105VZJ PTS System S100761_00661 ENOG4105VCP PTS System S100761_00662 ENOG4105CK1 PTS System S100761_00663 ENOG4105CS2 ec 3.2.1.21 S100761_00664 ENOG4108TZY GntR Family Transcriptional Regulator S100761_00665 ENOG4105EVU fructokinase S100761_00666 ENOG4105DG6 mannose-6-phosphate isomerase S100761_00667 ENOG4105D3P Mannan endo-1,4-beta-mannosidase S100761_00676 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) S100761_00677 ENOG4105K8N protein family UPF0079, ATPase S100761_00678 ENOG41072GX Peptidase M22 Glycoprotease S100761_00679 ENOG410801F ribosomal-protein-alanine acetyltransferase S100761_00680 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) S100761_00681 ENOG4105C5H ABC transporter S100761_00682 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) S100761_00683 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) S100761_00684 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) S100761_00685 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) S100761_00687 ENOG4108TYN CAAX amino terminal protease family protein S100761_00688 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) S100761_00689 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) S100761_00691 ENOG4105PGZ NB-ARC domain S100761_00692 ENOG4105CPQ Dehydrogenase S100761_00693 ENOG4105CT4 transporter S100761_00695 ENOG41087YS Phage shock protein A S100761_00696 ENOG4105DQX Zinc finger domain S100761_00697 ENOG4108WV1 Pfam:DUF477 S100761_00699 ENOG4108ZMR Ion transport 2 domain-containing protein S100761_00700 ENOG4107QNK )-transporter S100761_00706 ENOG4107YUH hydrolase S100761_00708 ENOG4107STQ Multicopper oxidase S100761_00709 ENOG4105C85 amino acid S100761_00711 ENOG4105C7R Atpase associated with various cellular activities aaa_3 S100761_00717 ENOG4105C7N Xanthine uracil vitamin C permease S100761_00722 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) S100761_00723 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit S100761_00724 ENOG4105C83 adenylosuccinate lyase S100761_00725 ENOG4105C8V SAICAR synthetase S100761_00726 ENOG4105VR9 phosphoribosylformylglycinamidine synthase S100761_00727 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I S100761_00728 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii S100761_00730 ENOG4105CXB phosphoribosylaminoimidazole synthetase S100761_00731 ENOG4108V3E phosphoribosylglycinamide formyltransferase S100761_00732 ENOG4105DC1 bifunctional purine biosynthesis protein purh S100761_00733 ENOG4105C12 Phosphoribosylglycinamide synthetase S100761_00735 ENOG4105DVH amino acid S100761_00738 ENOG4108R5T secreted protein S100761_00739 ENOG4105KGF protein, YerC YecD S100761_00740 ENOG4105CBC glutamate synthase S100761_00741 ENOG4105CBC glutamate synthase S100761_00743 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) S100761_00744 ENOG4105C4R Atp-dependent dna helicase S100761_00745 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) S100761_00747 ENOG4105CRN Aminoglycoside phosphotransferase S100761_00748 ENOG4105KT7 mgtC SapB transporter S100761_00749 ENOG4105CK7 Sodium proline symporter S100761_00750 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) S100761_00751 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) S100761_00752 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) S100761_00753 ENOG4108IG5 Transcriptional regulator S100761_00755 ENOG4105CBD Diacylglycerol kinase S100761_00756 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) S100761_00773 ENOG4108HFV S100761_00777 ENOG4105CDY transcriptional regulatory protein S100761_00779 ENOG4105M4P Tetr family transcriptional regulator S100761_00780 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein S100761_00781 ENOG4107S9F NmrA family S100761_00784 ENOG4105WEF catalase S100761_00785 ENOG4105M18 -acetyltransferase S100761_00788 ENOG4105C2F Histidine kinase S100761_00789 ENOG4105EQD regulatoR S100761_00790 ENOG410769Z extracellular solute-binding protein family 1 S100761_00791 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component S100761_00792 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component S100761_00793 ENOG4105F5H Glycosyl Hydrolase Family 88 S100761_00794 ENOG41075H3 AraC family transcriptional regulator S100761_00795 ENOG4107TDE lipolytic protein G-D-S-L family S100761_00798 ENOG4105CX8 fg-gap repeat protein S100761_00799 ENOG4105CX8 fg-gap repeat protein S100761_00800 ENOG4107TDE lipolytic protein G-D-S-L family S100761_00802 ENOG4105EKC S100761_00803 ENOG4105E0S extracellular solute-binding protein family 1 S100761_00805 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component S100761_00806 ENOG4105F8D glycoside hydrolase family 4 S100761_00807 ENOG4105H67 Protein of unknown function (DUF421) S100761_00808 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) S100761_00809 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily S100761_00812 ENOG4106I4J membrane S100761_00813 ENOG4108PCN EamA-like transporter family S100761_00814 ENOG41082F9 transcriptional regulator S100761_00815 ENOG41061H0 Monooxygenase S100761_00816 ENOG4108R1P S100761_00817 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) S100761_00818 ENOG4105E0M Sulfatase S100761_00819 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase S100761_00821 ENOG41090R9 glycosyltransferase S100761_00822 ENOG4107R51 Glycosyl transferase, family 2 S100761_00823 ENOG41090R9 glycosyltransferase S100761_00824 ENOG4105EU0 Major facilitator Superfamily S100761_00826 ENOG4105CUB amino acid S100761_00827 ENOG4105C26 Dehydrogenase S100761_00828 ENOG4105FKZ Methyl-accepting chemotaxis S100761_00829 ENOG4105C5H ABC transporter S100761_00831 ENOG4107SWG transcriptional regulator MERR family S100761_00832 ENOG4105DXB Major Facilitator superfamily S100761_00834 ENOG4105C5H ABC transporter S100761_00835 ENOG4105FDU atp-dependent rna helicase S100761_00837 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein S100761_00838 ENOG4105E0A ABC, transporter S100761_00839 ENOG4108U1V ABC transporter, permease S100761_00840 ENOG4105DQ5 transport system permease protein S100761_00841 ENOG4108HUF Transporter S100761_00844 ENOG4108J20 pectate lyase S100761_00845 ENOG4107QPK )-transporter S100761_00847 ENOG4108MRH transcriptional regulatory protein S100761_00852 ENOG410855V Acylphosphatase S100761_00853 ENOG4108RPX mosc domain containing protein S100761_00857 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) S100761_00863 ENOG4105E1K spore germination protein S100761_00864 ENOG4105C5Y PTS System S100761_00865 ENOG4105CG3 alpha amylase, catalytic region S100761_00866 ENOG4107414 GntR family transcriptional regulator S100761_00867 ENOG4108RCM Nitroreductase S100761_00868 ENOG4105CGH 5'-nucleotidase S100761_00869 ENOG4107RKG DJ-1/PfpI family S100761_00872 ENOG4105KJF protein tyrosine phosphatase S100761_00874 ENOG4107U9T Pfam:Ribonuclease_BN S100761_00876 ENOG4108ISG Major Facilitator S100761_00877 ENOG4105UPD Calcium Proton S100761_00879 ENOG4105D8X mechanosensitive ion channel S100761_00883 ENOG4106KE4 Dehydrogenase S100761_00884 ENOG4105D7N magnesium and cobalt transport protein CorA S100761_00886 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) S100761_00892 ENOG4107RUY (E1 component), alpha subunit S100761_00894 ENOG4107QKR Dehydrogenase S100761_00896 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family S100761_00897 ENOG41069DP small acid-soluble spore protein S100761_00898 ENOG4105KK4 UPF0060 membrane protein S100761_00904 ENOG4105F8D glycoside hydrolase family 4 S100761_00905 ENOG4108Q3X Transcriptional regulator S100761_00906 ENOG4105CI1 PTS System S100761_00908 ENOG4105BZ1 (ABC) transporter S100761_00909 ENOG4105BZ1 (ABC) transporter S100761_00911 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase S100761_00912 ENOG4105BZU Histidine kinase S100761_00913 ENOG4105WH1 Two component transcriptional regulator luxr family S100761_00914 ENOG4105CJ1 ABC, transporter S100761_00915 ENOG41090VJ ABC-2 type transporter S100761_00916 ENOG4108KYE ABC-2 type transporter S100761_00917 ENOG4105U3E Transcriptional regulator S100761_00918 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold S100761_00919 ENOG4105H93 Acyltransferase family S100761_00920 ENOG4105YA8 Transcriptional regulator S100761_00921 ENOG4107Y80 Major Facilitator superfamily S100761_00922 ENOG4108YYS metal-dependent hydrolase (By similarity) S100761_00923 ENOG4105C0R drug resistance transporter emrb qaca subfamily S100761_00924 ENOG410834F Transcriptional regulator S100761_00926 ENOG4108MES Periplasmic binding protein S100761_00927 ENOG4105DQ5 transport system permease protein S100761_00928 ENOG4108IHU transport system permease protein S100761_00929 ENOG4105JAB phenazine biosynthesis protein, phzf family S100761_00930 ENOG4107Y03 Nitroreductase S100761_00933 ENOG4105ECP epimerase S100761_00936 ENOG4105F27 Major Facilitator S100761_00940 ENOG4106AKJ S100761_00941 ENOG4105D74 hydrolase S100761_00942 ENOG4105CKK Glycosyl transferase, family 2 S100761_00943 ENOG4105EJV Membrane S100761_00944 ENOG41067AE Membrane-bound metal-dependent hydrolase S100761_00945 ENOG4105CEN a g-specific adenine glycosylase S100761_00946 ENOG4106BXE S100761_00947 ENOG4105CAN Short-chain dehydrogenase reductase Sdr S100761_00950 ENOG4105EVI UPF0374 protein S100761_00951 ENOG4105BZ1 (ABC) transporter S100761_00952 ENOG4107NBY Membrane S100761_00954 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen S100761_00955 ENOG4105G5W regulator Fur family S100761_00977 ENOG4108N23 SpoOM-related protein S100761_00979 ENOG4105EC3 peptidase S51, dipeptidase E S100761_00980 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) S100761_00983 ENOG4105E2Y ABC, transporter S100761_00984 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein S100761_00985 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component S100761_00986 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) S100761_00988 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) S100761_00989 ENOG4107D63 S100761_00990 ENOG4105VZ8 Transcriptional regulator S100761_00993 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) S100761_00995 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) S100761_00999 ENOG4105CYN Serine protein kinase S100761_01000 ENOG4106AKX UPF0229 protein S100761_01001 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes S100761_01002 ENOG4105CW7 secretion protein, HlyD family S100761_01003 ENOG4105C0R drug resistance transporter emrb qaca subfamily S100761_01004 ENOG4105CS1 NAD(P)H quinone oxidoreductase S100761_01007 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family S100761_01008 ENOG4105CZV ABC transporter S100761_01009 ENOG4105CJ1 ABC, transporter S100761_01010 ENOG4108TU7 Inherit from COG: (ABC) transporter S100761_01011 ENOG4105VEQ Cold shock protein S100761_01013 ENOG4105BZU Histidine kinase S100761_01020 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) S100761_01031 ENOG4105P1M Domain of unknown function (DUF1874) S100761_01033 ENOG4105K4H Nlp p60 protein S100761_01047 ENOG4108YBP pseudouridine synthase S100761_01049 ENOG41080XP Cbs domain S100761_01050 ENOG4107YBY Hydrolase S100761_01051 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase S100761_01052 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) S100761_01053 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator S100761_01055 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) S100761_01056 ENOG4105C6V Glycerol-3-phosphate dehydrogenase S100761_01058 ENOG4105BZU Histidine kinase S100761_01059 ENOG4105WH1 Two component transcriptional regulator luxr family S100761_01066 ENOG4105ED1 spovr family S100761_01067 ENOG4105G6Z alkaline phosphatase S100761_01070 ENOG4105BZN citrate synthase S100761_01071 ENOG4105CYX Short-chain dehydrogenase reductase Sdr S100761_01072 ENOG4105CUB amino acid S100761_01073 ENOG4105C8J )-transporter S100761_01074 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family S100761_01077 ENOG4105J37 S100761_01078 ENOG4108AEY RNA polymerase sigma factor S100761_01079 ENOG4108FN7 Aldo keto reductase S100761_01080 ENOG4105F6E Acyl-transferase S100761_01081 ENOG4105C37 (CBS) domain S100761_01083 ENOG4105CHM Aminotransferase S100761_01084 ENOG4105C37 (CBS) domain S100761_01086 ENOG4105WMR Protein CrcB homolog S100761_01087 ENOG4108QXE glycerophosphoryl diester phosphodiesterase S100761_01089 ENOG4105D64 Mechanosensitive ion channel S100761_01090 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) S100761_01091 ENOG4107VMI polysaccharide deacetylase S100761_01092 ENOG4105F0I Aminotransferase S100761_01095 ENOG4105BZ1 (ABC) transporter S100761_01096 ENOG4105BZ1 (ABC) transporter S100761_01100 ENOG410839P S100761_01102 ENOG4106MP8 UPF0754 membrane protein S100761_01103 ENOG4105WZB UPF0342 protein S100761_01104 ENOG4105F1N DNA alkylation repair S100761_01106 ENOG4105D4P Coproporphyrinogen iii oxidase S100761_01107 ENOG4107S91 Sodium hydrogen exchanger S100761_01108 ENOG4105NCW Trka-c domain protein S100761_01110 ENOG4105CGU Enoyl-CoA hydratase S100761_01112 ENOG4108IUX (ABC) transporter S100761_01113 ENOG4105RHA ABC transporter, permease S100761_01114 ENOG4107VRP DNA repair exonuclease S100761_01115 ENOG4106D4I domain protein S100761_01116 ENOG4105EQI Metal Dependent Phosphohydrolase S100761_01118 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) S100761_01124 ENOG4105NBU tryptophan transport protein S100761_01125 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) S100761_01126 ENOG4105K59 histidine triad (HIT) protein S100761_01133 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation S100761_01134 ENOG4105BZ4 penicillin-binding protein S100761_01135 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) S100761_01136 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) S100761_01137 ENOG4105C1Q protoporphyrinogen oxidase S100761_01139 ENOG4105ECB domain protein S100761_01141 ENOG41090T1 Membrane S100761_01143 ENOG4105DER m42 family S100761_01146 ENOG4108RQ5 Beta-lactamase domain-containing protein S100761_01147 ENOG4105DF9 Lipoate-protein, ligase S100761_01149 ENOG4105CEY Amp-dependent synthetase and ligase S100761_01151 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 S100761_01153 ENOG4105KD7 acetyltransferase S100761_01155 ENOG4108HUF Transporter S100761_01156 ENOG4107TB6 phosphoglycerate mutase S100761_01158 ENOG4107F3J Amp-dependent synthetase and ligase S100761_01159 ENOG4107ZYJ bioY protein S100761_01160 ENOG4106YBV Methyl-accepting chemotaxis S100761_01164 ENOG4105XVF Competence transcription factor S100761_01165 ENOG4105CYX Short-chain dehydrogenase reductase Sdr S100761_01166 ENOG4105X3H Excalibur domain protein S100761_01167 ENOG4105E1V na solute symporter S100761_01168 ENOG4106CAD Protein of unknown function (DUF3311) S100761_01169 ENOG41060YP S100761_01172 ENOG4107SCK Monooxygenase S100761_01173 ENOG4108INS Transcriptional regulator S100761_01178 ENOG4105TRI Hydrolase S100761_01181 ENOG4108KK1 membrane protein AbrB duplication S100761_01182 ENOG4106K7D Major facilitator family transporter S100761_01183 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) S100761_01186 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation S100761_01188 ENOG4105EYH Exonuclease S100761_01198 ENOG4105ERH Fumarylacetoacetate hydrolase S100761_01200 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin S100761_01202 ENOG4105CAQ asparagine synthetase S100761_01205 ENOG4105UQX Mate efflux family protein S100761_01206 ENOG4106HBX Transcriptional Regulator AraC Family S100761_01207 ENOG4105ETE Transcriptional regulator (LacI family S100761_01208 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) S100761_01209 ENOG4105SF0 DinB family S100761_01210 ENOG4108ZUB Lysine exporter protein (Lyse ygga) S100761_01211 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family S100761_01212 ENOG4105MYW Pentapeptide repeat protein S100761_01213 ENOG4107S9D Alpha beta hydrolase S100761_01214 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) S100761_01215 ENOG4107RIQ Sulfate adenylate transferase S100761_01216 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) S100761_01217 ENOG4108N5B 2-phosphosulfolactate phosphatase S100761_01218 ENOG41061P3 phosphosulfolactate synthase S100761_01221 ENOG4105DIA mandelate racemase muconate lactonizing S100761_01222 ENOG4107RCC Major Facilitator Superfamily S100761_01223 ENOG4108SZE gCN5-related N-acetyltransferase S100761_01224 ENOG4105MA6 gCN5-related N-acetyltransferase S100761_01226 ENOG4108VPT UPF0234 protein S100761_01227 ENOG4105QNR S1 RNA binding domain protein S100761_01231 ENOG4105K7K Transcriptional regulator S100761_01233 ENOG410751J S100761_01234 ENOG4105D4Y metalloprotease S100761_01235 ENOG4105EPR degv family S100761_01236 ENOG4107AYK membrAne S100761_01238 ENOG41073B9 S100761_01240 ENOG4108KP7 hydrolase S100761_01241 ENOG4108MXZ Esterase S100761_01242 ENOG4105VG1 fes assembly suf system protein S100761_01244 ENOG4105IQ5 FAD linked oxidase domain protein S100761_01247 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase S100761_01250 ENOG4105C8Y Acetylornithine aminotransferase S100761_01251 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain S100761_01253 ENOG4105DBV ornithine carbamoyltransferase S100761_01259 ENOG4107RMD Basic membrane lipoprotein S100761_01262 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) S100761_01263 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) S100761_01265 ENOG4105C3U ABC transporter S100761_01266 ENOG4108JQ7 (ABC) transporter S100761_01269 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component S100761_01271 ENOG4105C31 Tryptophanyl-tRNA synthetase S100761_01272 ENOG4108J59 Extracellular solute-binding protein, family 5 S100761_01273 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component S100761_01274 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component S100761_01276 ENOG4108JQ7 (ABC) transporter S100761_01279 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) S100761_01280 ENOG4108ZCF integral membrane protein S100761_01281 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis S100761_01283 ENOG4105DPN Oligoendopeptidase f S100761_01285 ENOG4105T58 Dithiol-disulfide isomerase S100761_01286 ENOG4108Z18 K06886 hemoglobin S100761_01287 ENOG4105E4C Lytic transglycosylase catalytic S100761_01288 ENOG4105MIX Adenylate cyclase S100761_01291 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) S100761_01292 ENOG4105EMS pseudouridine synthase S100761_01295 ENOG4105ETU transcriptional activator (TenA S100761_01296 ENOG4108VEU Thiamine monophosphate synthase S100761_01299 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) S100761_01300 ENOG4105D06 uba thif-type nad fad binding protein S100761_01301 ENOG4105DWF phosphomethylpyrimidine kinase S100761_01302 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH S100761_01303 ENOG4107A88 S100761_01313 ENOG4105ENA helicase S100761_01316 ENOG4108ZMI UPF0477 protein S100761_01318 ENOG4105C28 cystathionine S100761_01319 ENOG4105C28 cystathionine S100761_01320 ENOG4105D9U N-acetyltransferase S100761_01321 ENOG4105JHY Membrane S100761_01325 ENOG410635T phage-like element pbsx protein S100761_01334 ENOG4105DQ6 Transposase S100761_01335 ENOG4108NMT An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity) S100761_01345 ENOG410780I phosphoprotein phosphatase activity S100761_01346 ENOG4106BHF S100761_01347 ENOG4106ANW SMI1_KNR4 S100761_01365 ENOG4105DM4 PTS System S100761_01366 ENOG4105DM4 PTS System S100761_01367 ENOG4105DG6 mannose-6-phosphate isomerase S100761_01368 ENOG4105G7B Protein of unknown function (DUF2992) S100761_01369 ENOG4105VMI -acetyltransferase S100761_01371 ENOG4108Z66 YbaK ebsC protein S100761_01374 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) S100761_01376 ENOG4108ZJ4 polysaccharide deacetylase S100761_01377 ENOG4107CUJ Protein of unknown function (DUF2690) S100761_01382 ENOG4108IEG Formate dehydrogenase Alpha subunit S100761_01387 ENOG4106A3M Cytochrome p-450 S100761_01388 ENOG41087PP glycosyltransferase MGT family S100761_01390 ENOG4105EXQ uroporphyrinogen iii synthase hem4 S100761_01391 ENOG4105C4B ABC transporter, permease S100761_01392 ENOG4108IXI (ABC) transporter S100761_01394 ENOG4105Q95 Cupin 2, conserved barrel domain protein S100761_01397 ENOG4105D2H Uronic isomerase S100761_01398 ENOG4105CT4 transporter S100761_01399 ENOG4105DG4 malate L-lactate dehydrogenase S100761_01400 ENOG4105CPQ Dehydrogenase S100761_01401 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) S100761_01402 ENOG4105DMW Dehydrogenase reductase S100761_01403 ENOG4108I5G Major Facilitator superfamily S100761_01404 ENOG4107KJX Transcriptional regulator S100761_01405 ENOG4107QZW Altronate oxidoreductase S100761_01406 ENOG4105CTX dehydratase S100761_01407 ENOG4107TSN permease S100761_01409 ENOG4105JD4 ATPase yjob S100761_01412 ENOG41068K0 YCII-related domain S100761_01413 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase S100761_01414 ENOG4105KWG Pfam:DUF1696 S100761_01415 ENOG4105K7W phage-related replication protein S100761_01416 ENOG4105WEF catalase S100761_01417 ENOG410635T phage-like element pbsx protein S100761_01427 ENOG4108TFU terminase (Small subunit) S100761_01428 ENOG4105IG6 Phage terminase, large subunit S100761_01429 ENOG4108MDF Phage Portal Protein S100761_01434 ENOG41060SN S100761_01436 ENOG4105PQS phage protein S100761_01437 ENOG4105FR7 XkdM protein, phage-like element PBSX S100761_01438 ENOG4105MTC XkdN-like protein S100761_01439 ENOG4108FKH Transglycosylase SLT domain S100761_01439 ENOG4108FKH Transglycosylase SLT domain S100761_01439 ENOG4108FKH Transglycosylase SLT domain S100761_01440 ENOG4108WZM domain protein S100761_01441 ENOG4105X7F S100761_01443 ENOG4105MFU Protein of unknown function (DUF2634) S100761_01444 ENOG41066EA baseplate J family protein S100761_01445 ENOG410906S phage-like element pbsx protein xkdt S100761_01447 ENOG41068G1 S100761_01453 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase S100761_01456 ENOG4105CJ3 phosphate transporter S100761_01457 ENOG4107GRR phosphate transport regulator S100761_01458 ENOG4107R7I amino acid S100761_01460 ENOG4105EDW glycosyl transferase, family 39 S100761_01461 ENOG4105CKK Glycosyl transferase, family 2 S100761_01463 ENOG4105C0H protease S100761_01465 ENOG4108ME1 Peptidase M55 D-aminopeptidase S100761_01466 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component S100761_01467 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component S100761_01468 ENOG4105C3U ABC transporter S100761_01471 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A S100761_01472 ENOG4105DTQ mandelate racemase muconate lactonizing S100761_01473 ENOG4107SN7 NLP P60 protein S100761_01474 ENOG4108JQ7 (ABC) transporter S100761_01475 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) S100761_01476 ENOG4107TUM Amidinotransferase S100761_01477 ENOG4108S4H thioesterase Superfamily protein S100761_01478 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) S100761_01482 ENOG4108428 Inherit from COG: -acetyltransferase S100761_01484 ENOG41080TC multidrug resistance protein S100761_01485 ENOG4105CIY formyltetrahydrofolate deformylase S100761_01486 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) S100761_01489 ENOG4105K56 Transcriptional regulator S100761_01490 ENOG4108ZHJ Organic hydroperoxide resistance protein S100761_01491 ENOG4107Y2X deaminase S100761_01492 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) S100761_01493 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin S100761_01495 ENOG4108W7F transporter, permease S100761_01496 ENOG4108JJB ABC transporter S100761_01497 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein S100761_01498 ENOG4108X43 YKOF domain protein S100761_01499 ENOG4105CK6 Two component transcriptional regulator (Winged helix family S100761_01500 ENOG41062D9 Histidine kinase S100761_01502 ENOG4106849 propeptide, pepSY amd peptidase M4 S100761_01505 ENOG4105CJW magnesium transporter S100761_01506 ENOG4105V75 Transcriptional regulator S100761_01515 ENOG4105DQE DNA ligase S100761_01516 ENOG4105FDF Could be involved in DNA repair (By similarity) S100761_01517 ENOG4105BZU Histidine kinase S100761_01518 ENOG4107T5V SNARE associated Golgi S100761_01519 ENOG4107TS3 membrane protein, TerC S100761_01520 ENOG4108WZW RNA polymerase sigma S100761_01522 ENOG410681C small acid-soluble spore protein S100761_01524 ENOG4105D0M Protease HtpX homolog S100761_01528 ENOG4108TGC Acyltransferase S100761_01529 ENOG4105BZU Histidine kinase S100761_01530 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) S100761_01532 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) S100761_01533 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) S100761_01534 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase S100761_01536 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit S100761_01537 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) S100761_01538 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) S100761_01539 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) S100761_01543 ENOG4105BZU Histidine kinase S100761_01544 ENOG41090MY MarR family Transcriptional regulator S100761_01545 ENOG4105ER2 Ompa motb domain protein S100761_01546 ENOG4105E14 MotA TolQ exbB proton channel S100761_01548 ENOG4108K88 Membrane S100761_01549 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) S100761_01550 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase S100761_01551 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) S100761_01552 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) S100761_01554 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr S100761_01555 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) S100761_01563 ENOG4107RRE RNA-directed DNA polymerase S100761_01568 ENOG4105F0V Cell wall hydrolase S100761_01571 ENOG4105C59 p-type ATPase S100761_01573 ENOG4105DC7 peptidase M24 S100761_01576 ENOG4105CID antiterminator S100761_01578 ENOG4105KRI phosphocarrier protein (HPr S100761_01579 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) S100761_01581 ENOG4105F6S Spore photoproduct lyase S100761_01583 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer S100761_01584 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase S100761_01585 ENOG4105K4I Scp-like extracellular S100761_01587 ENOG4105BZU Histidine kinase S100761_01588 ENOG4105CHM Aminotransferase S100761_01590 ENOG4107R88 Chemotaxis protein (CheV) S100761_01591 ENOG4105UIN S100761_01593 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein S100761_01595 ENOG4105K6S Short-chain dehydrogenase reductase Sdr S100761_01596 ENOG4105EPM Diguanylate phosphodiesterase S100761_01597 ENOG4107IN1 Protein of unknown function (DUF1797) S100761_01598 ENOG4108XRC Protein of unknown function (DUF458) S100761_01604 ENOG4105NQC Flavodoxin S100761_01606 ENOG4105CH2 amidohydrolase S100761_01608 ENOG4105D8X mechanosensitive ion channel S100761_01609 ENOG4105D3R alkyl hydroperoxide reductase S100761_01610 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen S100761_01613 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) S100761_01614 ENOG4105D06 uba thif-type nad fad binding protein S100761_01615 ENOG4105CVM Molybdenum cofactor synthesis domain protein S100761_01616 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein S100761_01617 ENOG4108ZAF Molybdopterin S100761_01618 ENOG41067WU Molybdopterin converting factor (Subunit 1) S100761_01619 ENOG4105BZ1 (ABC) transporter S100761_01620 ENOG4105BZ1 (ABC) transporter S100761_01622 ENOG4107X8C Efflux transporter RND family MFP subunit S100761_01623 ENOG4105C19 ABC transporter S100761_01624 ENOG4107RBB ABC transporter, permease S100761_01625 ENOG4105E98 transcriptional regulator DeoR family S100761_01626 ENOG4105DE4 1-phosphofructokinase S100761_01627 ENOG4105DM4 PTS System S100761_01628 ENOG4105C3F Signal peptidase i S100761_01630 ENOG4105C5H ABC transporter S100761_01631 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) S100761_01636 ENOG4105BZU Histidine kinase S100761_01638 ENOG4107ZYR domain protein S100761_01640 ENOG4105CN5 Metallo-Beta-Lactamase S100761_01642 ENOG4108X4Q Hydrolase S100761_01643 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) S100761_01648 ENOG4105CPP Dehydrogenase, E1 component S100761_01649 ENOG4105C7S Dehydrogenase S100761_01650 ENOG4107QN2 dihydrolipoyl dehydrogenase S100761_01653 ENOG4105CXN decarboxylase S100761_01654 ENOG4105WBI UPF0223 protein S100761_01657 ENOG4105ECY inositol monophosphatase S100761_01659 ENOG4105JQZ Methyltransferase S100761_01667 ENOG4105CI3 gtp-binding protein typa S100761_01668 ENOG4105QA2 S100761_01671 ENOG4108IAB Phoh family S100761_01673 ENOG4105CSV Glutaminase S100761_01674 ENOG4105ZPI UPF0358 protein S100761_01675 ENOG4105CNI cell division protein FtsW S100761_01676 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) S100761_01678 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) S100761_01680 ENOG4105BZ9 Cytochrome C oxidase, subunit I S100761_01681 ENOG4105CCU oxidase (Subunit III) S100761_01682 ENOG41064X9 cytochrome C oxidase subunit IV S100761_01685 ENOG41080XQ Signal transduction protein with cbs domains S100761_01686 ENOG4106UY4 Inherit from COG: Scp-like extracellular S100761_01690 ENOG4105WUC UPF0298 protein S100761_01691 ENOG4106H78 methyltransferase S100761_01692 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) S100761_01693 ENOG4105H20 Sporulation integral membrane protein YlbJ S100761_01694 ENOG4105D78 K07001 NTE family protein S100761_01695 ENOG41063PX domain protein S100761_01696 ENOG4105CDE UPF0348 protein S100761_01698 ENOG4105KNH Nucleic acid-binding protein S100761_01699 ENOG41067VY 50S ribosomal protein L32 S100761_01704 ENOG4108V6E Cell division protein mraZ S100761_01705 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) S100761_01707 ENOG4105CJN penicillin-binding protein S100761_01708 ENOG4105CJN penicillin-binding protein S100761_01709 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) S100761_01710 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) S100761_01711 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) S100761_01712 ENOG4105CNI cell division protein FtsW S100761_01713 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) S100761_01714 ENOG4105D4A Cell wall formation (By similarity) S100761_01715 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) S100761_01716 ENOG4108R2U division initiation protein S100761_01718 ENOG4105K67 small basic protein S100761_01719 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) S100761_01720 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) S100761_01723 ENOG4105FFI sigma-e processing peptidase spoiiga S100761_01724 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) S100761_01726 ENOG4105DKW ABC transporter S100761_01729 ENOG4105WR5 sporulation protein, YlmC YmxH family S100761_01730 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase S100761_01731 ENOG4105DFA alanine racemase domain protein S100761_01732 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) S100761_01733 ENOG41067XK integral membrane protein S100761_01734 ENOG4105DBK s4 domain protein S100761_01736 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) S100761_01738 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) S100761_01739 ENOG4105C34 Pseudouridine synthase S100761_01740 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) S100761_01742 ENOG4105CXT aspartate transcarbamylase S100761_01744 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain S100761_01745 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain S100761_01746 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) S100761_01747 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) S100761_01748 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) S100761_01749 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) S100761_01750 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) S100761_01752 ENOG4107S4M Sulfate adenylate transferase S100761_01753 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) S100761_01754 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) S100761_01755 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) S100761_01756 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein S100761_01757 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein S100761_01758 ENOG4105F23 Fibronectin-binding protein S100761_01760 ENOG4105DSJ YicC domain protein S100761_01761 ENOG4105KC4 UPF0296 protein S100761_01762 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) S100761_01764 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase S100761_01765 ENOG4105C25 Primosomal protein n' S100761_01766 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) S100761_01767 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) S100761_01768 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B S100761_01769 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs S100761_01770 ENOG4108ZF3 Phosphatase S100761_01771 ENOG4105D9P serine threonine protein kinase S100761_01772 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) S100761_01773 ENOG4105DJV ribulose-phosphate 3-epimerase S100761_01774 ENOG4105FJ0 thiamine S100761_01775 ENOG4105VB9 50S ribosomal protein l28 S100761_01776 ENOG4108ZAA Alkaline-shock protein S100761_01777 ENOG4105DP4 dak2 domain fusion protein ylov S100761_01779 ENOG4105EJQ L-serine dehydratase S100761_01780 ENOG4105CB5 ATP-dependent DNA helicase recG S100761_01781 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) S100761_01783 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase S100761_01784 ENOG4105CHR reductase S100761_01785 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) S100761_01786 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) S100761_01787 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) S100761_01788 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) S100761_01790 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) S100761_01792 ENOG4105K5M 30s ribosomal protein S16 S100761_01793 ENOG4108BW8 UPF0109 protein S100761_01795 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) S100761_01796 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) S100761_01797 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) S100761_01798 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) S100761_01799 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) S100761_01801 ENOG4105VM1 flagellar S100761_01802 ENOG4105CMV Succinyl-CoA synthetase subunit beta S100761_01803 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha S100761_01804 ENOG4105C79 DNA protecting protein DprA S100761_01805 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) S100761_01806 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) S100761_01807 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) S100761_01808 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) S100761_01809 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) S100761_01811 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) S100761_01812 ENOG4108ZC9 flagellar basal-body rod protein flgc S100761_01813 ENOG4105VQ0 flagellar hook-basal body complex protein fliE S100761_01814 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) S100761_01815 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) S100761_01818 ENOG4106YF4 Flagellar biosynthesis chaperone S100761_01821 ENOG410696Y Flagellar hook-length control protein S100761_01822 ENOG410822I Flagellar hook capping protein S100761_01823 ENOG4108JQA flagellar S100761_01825 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) S100761_01826 ENOG4105DD5 Flagellar motor switch protein S100761_01827 ENOG4107YTP response regulator receiver protein S100761_01829 ENOG4105CN7 Flagellar biosynthetic protein FliP S100761_01830 ENOG4105VS8 Flagellar biosynthetic protein fliq S100761_01831 ENOG4105D19 Role in flagellar biosynthesis (By similarity) S100761_01832 ENOG4105D00 flagellar biosynthetic protein flhB S100761_01833 ENOG4105D7B Flagellar biosynthesis protein flha S100761_01834 ENOG4105FZW flagellar biosynthesis regulator FlhF S100761_01836 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) S100761_01837 ENOG4105CBS Chea signal transduction histidine kinase S100761_01838 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis S100761_01841 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) S100761_01843 ENOG4105CE9 30S ribosomal protein S2 S100761_01844 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) S100761_01846 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) S100761_01847 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) S100761_01848 ENOG4105KNE Phosphatidate cytidylyltransferase S100761_01850 ENOG4105DZP Membrane-associated zinc metalloprotease S100761_01851 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) S100761_01852 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) S100761_01853 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) S100761_01854 ENOG4105CHV Transcription elongation factor NusA S100761_01855 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination S100761_01856 ENOG4105VHM ribosomal protein S100761_01857 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) S100761_01858 ENOG4105W7A Protein of unknown function (DUF503) S100761_01859 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) S100761_01860 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) S100761_01861 ENOG4105DTN riboflavin biosynthesis protein ribF S100761_01862 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) S100761_01863 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) S100761_01865 ENOG4105C1V Peptidase, M16 S100761_01867 ENOG4105E35 Dipicolinate synthase subunit A S100761_01868 ENOG4108S0H Dipicolinic acid synthetase, b subunit S100761_01869 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) S100761_01871 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) S100761_01873 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit S100761_01875 ENOG4105CNU cell division protein FtsK S100761_01876 ENOG4105FDP GntR family transcriptional regulator S100761_01880 ENOG4108RKS Short-chain dehydrogenase reductase Sdr S100761_01881 ENOG4105XZV Protein of unknown function (DUF3243) S100761_01884 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase S100761_01885 ENOG4105CEV competence damage-inducible protein S100761_01887 ENOG4108A04 Beta-lactamase S100761_01888 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) S100761_01889 ENOG4105D48 metallophosphoesterase S100761_01890 ENOG4105MCT stage V sporulation protein S S100761_01892 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) S100761_01893 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) S100761_01896 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) S100761_01897 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) S100761_01912 ENOG4105IIP Membrane S100761_01913 ENOG4105W1N transcriptional regulator S100761_01916 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin S100761_01917 ENOG4105K7W phage-related replication protein S100761_01918 ENOG4108X3M OsmC Ohr family protein S100761_01919 ENOG410814C multidrug resistance protein S100761_01923 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) S100761_01924 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) S100761_01927 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) S100761_01928 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) S100761_01929 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) S100761_01930 ENOG4105U6W MutT NUDIX family protein S100761_01931 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase S100761_01932 ENOG4106F1P AAA ATPase, central domain protein S100761_01933 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) S100761_01934 ENOG4105CXI aluminum resistance protein S100761_01935 ENOG4105KV4 Transcriptional regulator S100761_01936 ENOG4105C5F glutamine synthetase S100761_01937 ENOG41079P0 S100761_01941 ENOG4107AUC S100761_01947 ENOG4107NTZ S100761_01951 ENOG410907G S100761_01952 ENOG4105CT4 transporter S100761_01953 ENOG4105DSG hydrolase family 43 S100761_01954 ENOG4105E2R ROK family S100761_01955 ENOG4105C93 Xylose Isomerase S100761_01956 ENOG4105CMG Carbohydrate kinase S100761_01957 ENOG4107Y9E nuclease S100761_01958 ENOG4105C54 Major Facilitator superfamily S100761_01959 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) S100761_01961 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) S100761_01977 ENOG4108NHD germination protein S100761_01980 ENOG4105FVX S100761_01983 ENOG4105K7W phage-related replication protein S100761_01985 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) S100761_01986 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) S100761_01988 ENOG4108SVB resolvase S100761_01989 ENOG4105VPS UPF0291 protein S100761_01990 ENOG4105CV1 Transketolase (EC 2.2.1.1) S100761_01994 ENOG4107QIV Cytochrome c biogenesis protein S100761_01999 ENOG4107DZX Small, acid-soluble spore protein P S100761_02001 ENOG4108I0Z Aconitate hydratase S100761_02002 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen S100761_02005 ENOG41067CD Small, acid-soluble spore protein Tlp S100761_02007 ENOG4105MI2 S100761_02008 ENOG4105W8X HesB YadR YfhF-family protein S100761_02009 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) S100761_02010 ENOG4105K4P CoA-binding domain protein S100761_02011 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) S100761_02016 ENOG4107QWR cellulase (EC 3.2.1.4) S100761_02018 ENOG4108MYR Secreted protein S100761_02019 ENOG4107SYN Glycosyl hydrolases family 43 S100761_02020 ENOG4107SYN Glycosyl hydrolases family 43 S100761_02022 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase S100761_02023 ENOG4107T5V SNARE associated Golgi S100761_02025 ENOG4107QX3 carboxylase S100761_02026 ENOG4105E39 Enoyl-CoA hydratase S100761_02027 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase S100761_02028 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit S100761_02029 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase S100761_02030 ENOG4105CEY Amp-dependent synthetase and ligase S100761_02031 ENOG4105C1G acyl-Coa dehydrogenase S100761_02032 ENOG4105F32 YngK protein S100761_02033 ENOG4106U2H Protein of unknown function (DUF1360) S100761_02035 ENOG4105CEY Amp-dependent synthetase and ligase S100761_02036 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family S100761_02037 ENOG4108N2V aldose 1-epimerase S100761_02038 ENOG4107QJQ Mate efflux family protein S100761_02043 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) S100761_02044 ENOG4105SKE transcriptional Regulator LysR family S100761_02045 ENOG4105CB2 alcohol dehydrogenase S100761_02046 ENOG4105BZ8 glutamate synthase S100761_02047 ENOG4105CBC glutamate synthase S100761_02048 ENOG4105C5Q Transcriptional regulator S100761_02049 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) S100761_02050 ENOG4105II7 pyrroline-5-carboxylate reductase S100761_02054 ENOG4108UB7 S100761_02055 ENOG41068WN S100761_02056 ENOG4105IE8 Alpha-ketoglutarate permease S100761_02057 ENOG4107U6E carbohydrate kinase FGGY S100761_02058 ENOG4108M3J Dehydrogenase S100761_02059 ENOG4108J2R molybdopterin oxidoreductase S100761_02061 ENOG4107QNK )-transporter S100761_02062 ENOG4105CIB oxidoreductase Domain protein S100761_02063 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) S100761_02064 ENOG4105ETE Transcriptional regulator (LacI family S100761_02068 ENOG4105EC8 Methyl-accepting chemotaxis S100761_02070 ENOG4108YQE rare lipoprotein a S100761_02071 ENOG4108YQE rare lipoprotein a S100761_02072 ENOG4105XPP Protein of unknown function (DUF1275) S100761_02073 ENOG4108NR7 pectate lyase S100761_02074 ENOG4108RAV Conserved protein S100761_02077 ENOG4105F0F Oxalate decarboxylase S100761_02081 ENOG41073R8 VanW family S100761_02083 ENOG4105VMP Transcriptional regulator S100761_02084 ENOG4105NX3 Membrane S100761_02086 ENOG4108Q5Y Membrane S100761_02088 ENOG4108V4B ThiJ pfpI S100761_02089 ENOG4108J4B Beta-lactamase S100761_02092 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) S100761_02093 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) S100761_02094 ENOG4107T94 Endo-14-beta-xylanase S100761_02095 ENOG4105YB8 TM2 domain containing protein S100761_02108 ENOG4107NTZ S100761_02118 ENOG4105D9U N-acetyltransferase S100761_02120 ENOG4105D06 uba thif-type nad fad binding protein S100761_02121 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) S100761_02123 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) S100761_02127 ENOG4105UA4 acetyltransferase S100761_02128 ENOG4105UA4 acetyltransferase S100761_02131 ENOG4106ANW SMI1_KNR4 S100761_02132 ENOG4106BHF S100761_02135 ENOG4108Z7R Chaperone CsaA S100761_02136 ENOG4105FTV AraC Family Transcriptional Regulator S100761_02137 ENOG4108HJF gCN5-related N-acetyltransferase S100761_02139 ENOG4108W8B Beta-lactamase domain protein S100761_02141 ENOG4105D29 Helix-turn-helix type 11 domain protein S100761_02143 ENOG4105KTU Transcriptional regulator, arsr family S100761_02145 ENOG4108SJC Membrane S100761_02149 ENOG4105ECK Fatty Acid Desaturase S100761_02150 ENOG4108ZGX Histidine kinase S100761_02151 ENOG4108S01 response regulator S100761_02153 ENOG41069ER domain protein S100761_02154 ENOG4105C9U ATP-dependent DNA helicase RecQ S100761_02155 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) S100761_02156 ENOG4105SCY DNAK suppressor S100761_02164 ENOG4105C26 Dehydrogenase S100761_02165 ENOG4105EWU Squalene--hopene cyclase S100761_02166 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) S100761_02167 ENOG4105C8J )-transporter S100761_02168 ENOG4105C09 Bile acid S100761_02169 ENOG4105C7S Dehydrogenase S100761_02171 ENOG4107T89 von Willebrand factor, type A S100761_02172 ENOG4105GMT ATPase associated with various cellular activities aaa_5 S100761_02174 ENOG4105K4H Nlp p60 protein S100761_02175 ENOG41087PP glycosyltransferase MGT family S100761_02178 ENOG4107QMU Mate efflux family protein S100761_02179 ENOG4106SCS STAS domain S100761_02183 ENOG4105FR1 rard protein S100761_02186 ENOG4105C6Z Gluconate S100761_02187 ENOG4105C6Z Gluconate S100761_02188 ENOG41090U3 tautomerase S100761_02191 ENOG4105FBA Phospholipase Carboxylesterase S100761_02194 ENOG4105E1V na solute symporter S100761_02198 ENOG4108VXD carboxy-peptidase S100761_02199 ENOG4105D3A purine nucleoside phosphorylase DeoD-type S100761_02201 ENOG4106Z5R S100761_02202 ENOG410841Q phosphoesterase PA-phosphatase related protein S100761_02208 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein S100761_02209 ENOG4108TSC N-acetyltransferase S100761_02210 ENOG4107S4Y M20 DapE family protein YgeY S100761_02213 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) S100761_02221 ENOG4107T32 3-phytase (EC 3.1.3.8) S100761_02222 ENOG4105C5E polysaccharide biosynthesis protein S100761_02223 ENOG4105E0X reductase S100761_02224 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) S100761_02228 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) S100761_02229 ENOG41090WU lipolytic protein G-D-S-L family S100761_02230 ENOG4108KF3 Electron transport protein SCO1 SenC S100761_02232 ENOG4105C7B Threonine dehydratase S100761_02234 ENOG4108UT2 hemolysin iii S100761_02236 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) S100761_02239 ENOG4107YX5 Pfam:DUF548 S100761_02240 ENOG4108Y6J UPF0403 protein S100761_02241 ENOG4105C01 Dihydroxy-acid dehydratase S100761_02244 ENOG4108V06 Glutathione peroxidase S100761_02245 ENOG4105CVG Homoserine O-transsuccinylase S100761_02253 ENOG41081VK Ribonuclease S100761_02258 ENOG410890F Dynamin family S100761_02261 ENOG41065KQ synthase S100761_02262 ENOG4105C2W permease S100761_02263 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) S100761_02264 ENOG4105CTD carboxy-peptidase S100761_02265 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) S100761_02266 ENOG4108UHU Aldolase S100761_02267 ENOG4105D7K pfkb domain protein S100761_02268 ENOG4108M60 Transcriptional regulator S100761_02270 ENOG4105CHR reductase S100761_02271 ENOG4105DVT helicase S100761_02273 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) S100761_02275 ENOG4108UKS UPF0398 protein S100761_02276 ENOG4107X2U Inherit from COG: Exonuclease-like protein S100761_02277 ENOG4108I5C dEAD DEAH box helicase S100761_02287 ENOG4105BZ4 penicillin-binding protein S100761_02289 ENOG4105CSM endonuclease III S100761_02291 ENOG4105C5S asparaginyl-tRNA synthetase S100761_02292 ENOG4105CHM Aminotransferase S100761_02294 ENOG4105YAC S100761_02295 ENOG4105DVT helicase S100761_02296 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) S100761_02297 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) S100761_02298 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) S100761_02299 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase S100761_02300 ENOG4105DJ0 Poly(A) Polymerase S100761_02301 ENOG4105CPK Glycosyl transferase (Group 1 S100761_02302 ENOG4105FJR Lmbe family S100761_02303 ENOG4108Z5K methylglyoxal synthase S100761_02304 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) S100761_02305 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase S100761_02306 ENOG4108JYZ YitT family S100761_02310 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) S100761_02314 ENOG41068YB TPR repeat-containing protein S100761_02315 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase S100761_02319 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) S100761_02320 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase S100761_02322 ENOG4108I0Q anthranilate phosphoribosyltransferase S100761_02323 ENOG4105CRQ synthase (Component I) S100761_02324 ENOG4105KHN chorismate mutase S100761_02325 ENOG4105D49 3-dehydroquinate synthase S100761_02326 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase S100761_02327 ENOG4105BZU Histidine kinase S100761_02328 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) S100761_02329 ENOG4105EAH synthase S100761_02330 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) S100761_02331 ENOG4105XXQ heptaprenyl diphosphate synthase component I S100761_02333 ENOG4105EUJ GTP cyclohydrolase i S100761_02334 ENOG4105K70 DNA-binding protein S100761_02335 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) S100761_02338 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase S100761_02339 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) S100761_02340 ENOG41065D1 S100761_02341 ENOG4105S2F S100761_02344 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) S100761_02345 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) S100761_02346 ENOG4105CAT Cytidine monophosphate kinase S100761_02349 ENOG4105MSI germination protein ypeb S100761_02351 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) S100761_02352 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase S100761_02355 ENOG4107RGJ metallophosphoesterase S100761_02358 ENOG4105I7S Abortive infection protein S100761_02359 ENOG4105C9U ATP-dependent DNA helicase RecQ S100761_02360 ENOG4105T7X S100761_02362 ENOG4108SAX Membrane S100761_02363 ENOG4108JQ1 Dehydrogenase S100761_02364 ENOG4105FF2 Type I DHQase S100761_02367 ENOG4105BZU Histidine kinase S100761_02368 ENOG4105CK6 Two component transcriptional regulator (Winged helix family S100761_02369 ENOG4105CRE cytochrome C S100761_02370 ENOG4107TWT Cytochrome c biogenesis protein S100761_02372 ENOG4105FE9 pseudouridine synthase S100761_02374 ENOG4108JIC nucleoside recognition domain protein S100761_02375 ENOG4105DZ1 carboxypeptidase S100761_02377 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) S100761_02378 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) S100761_02381 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) S100761_02382 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) S100761_02383 ENOG4108R6K riboflavin synthase, subunit alpha S100761_02384 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) S100761_02386 ENOG4105C3F Signal peptidase i S100761_02387 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) S100761_02389 ENOG4107ZE5 PPIases accelerate the folding of proteins S100761_02396 ENOG4107ZE5 PPIases accelerate the folding of proteins S100761_02397 ENOG4105PTM secreted protein S100761_02398 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) S100761_02400 ENOG4105G6R Stage v sporulation protein ae S100761_02402 ENOG4105CZ3 stage V sporulation protein ad S100761_02403 ENOG41090VF Stage v sporulation protein ac S100761_02406 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) S100761_02407 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) S100761_02408 ENOG41082AN stage II sporulation protein S100761_02409 ENOG4105DZ1 carboxypeptidase S100761_02410 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) S100761_02411 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) S100761_02412 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) S100761_02414 ENOG4105I3K Ferric uptake regulator, Fur family S100761_02415 ENOG4105MZ9 stage II sporulation protein m S100761_02418 ENOG4105DFD Na H antiporter S100761_02419 ENOG4108IJ0 Aspartate ammonia-lyase S100761_02420 ENOG4105HDK L-asparaginase S100761_02421 ENOG4108IMY Transcriptional regulator S100761_02423 ENOG4108YZ4 nudix hydrolase S100761_02425 ENOG4105CPC Aldo Keto reductase S100761_02429 ENOG4106HZJ S100761_02430 ENOG4105RHY Pfam:UPF0157 S100761_02431 ENOG4105KAC Antibiotic biosynthesis monooxygenase S100761_02432 ENOG4108XET gCN5-related N-acetyltransferase S100761_02434 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) S100761_02436 ENOG4105E5W Transporter S100761_02438 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase S100761_02441 ENOG4108IXY short-chain dehydrogenase reductase S100761_02442 ENOG41069FQ Metallo-beta-lactamase superfamily S100761_02443 ENOG4105II7 pyrroline-5-carboxylate reductase S100761_02445 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase S100761_02447 ENOG410861F 50S ribosomal protein L33 S100761_02448 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) S100761_02449 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase S100761_02450 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) S100761_02451 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) S100761_02453 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) S100761_02454 ENOG4108NA0 Uncharacterized conserved protein (COG2071) S100761_02455 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) S100761_02456 ENOG4108HNZ carboxyl transferase S100761_02457 ENOG4108ZVT methylmalonyl-coA epimerase S100761_02459 ENOG4108VZI ErfK ybiS ycfS ynhG family protein S100761_02460 ENOG4108QEG Membrane S100761_02461 ENOG4105CDA abc transporter atp-binding protein S100761_02462 ENOG4105E5Q amino acid AbC transporter S100761_02463 ENOG4108HW3 (ABC) transporter S100761_02464 ENOG4108Y6J UPF0403 protein S100761_02465 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) S100761_02468 ENOG4105C7S Dehydrogenase S100761_02469 ENOG4105CPP Dehydrogenase, E1 component S100761_02472 ENOG4105CKM Branched-chain carboxylic acid kinase S100761_02473 ENOG4107RDP Dehydrogenase S100761_02475 ENOG4108JUB Transcriptional regulator S100761_02476 ENOG4106CCJ Protein of unknown function (DUF2627) S100761_02477 ENOG4105CR4 methylisocitrate lyase S100761_02478 ENOG4105DXD 2-methylcitrate dehydratase S100761_02480 ENOG4105C1G acyl-Coa dehydrogenase S100761_02481 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase S100761_02483 ENOG4108QXE glycerophosphoryl diester phosphodiesterase S100761_02484 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase S100761_02487 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase S100761_02489 ENOG4107QQR Sporulation S100761_02490 ENOG4105S1Z Stage IV sporulation protein B S100761_02491 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) S100761_02492 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) S100761_02493 ENOG4105DX0 Hemolysin A S100761_02495 ENOG4105CTB Polyprenyl synthetase S100761_02496 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) S100761_02497 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) S100761_02498 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) S100761_02499 ENOG4105M7K Involved in the transcription termination process (By similarity) S100761_02500 ENOG4108ZSR alkaline shock protein S100761_02501 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase S100761_02505 ENOG410644B Stage III sporulation protein af S100761_02507 ENOG4105KQ4 Stage iii sporulation protein ad S100761_02508 ENOG4108CQH stage III sporulation protein AC S100761_02509 ENOG4105KR5 Stage iii sporulation protein S100761_02510 ENOG4105CD2 stage iii sporulation protein aa S100761_02512 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) S100761_02513 ENOG4105DC7 peptidase M24 S100761_02514 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) S100761_02516 ENOG4105CBJ Metal-dependent enzyme S100761_02519 ENOG4105KST dependent repressor S100761_02520 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) S100761_02521 ENOG4105WZW rhodanese family S100761_02522 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor S100761_02523 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor S100761_02524 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) S100761_02525 ENOG4105C0D helicase S100761_02528 ENOG4108IMY Transcriptional regulator S100761_02530 ENOG4105VFR signal peptidase S100761_02541 ENOG41080XP Cbs domain S100761_02543 ENOG4105C37 (CBS) domain S100761_02548 ENOG4105C5X domain protein S100761_02553 ENOG4105E0M Sulfatase S100761_02556 ENOG4107ZXI Rhomboid family S100761_02558 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase S100761_02559 ENOG4105WDJ 50S ribosomal protein L33 S100761_02563 ENOG41068DG YceG-like family S100761_02564 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) S100761_02565 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) S100761_02566 ENOG4105E2Z phosphate ABC transporter (Permease S100761_02567 ENOG4105C8U phosphate abc transporter S100761_02568 ENOG4105CVA phosphate S100761_02569 ENOG4107RF6 penicillin-binding protein S100761_02571 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) S100761_02572 ENOG4105SXS Protein of unknown function (DUF456) S100761_02575 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) S100761_02576 ENOG41063Y9 S100761_02577 ENOG4108U5J '-nucleotidase S100761_02578 ENOG4105N80 Ferric uptake regulator, Fur family S100761_02579 ENOG4108JYZ YitT family S100761_02580 ENOG41069ZM Protein of unknown function (DUF2624) S100761_02581 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) S100761_02584 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) S100761_02585 ENOG4105EGD dinuclear metal center protein, YbgI family S100761_02588 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) S100761_02589 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) S100761_02590 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 S100761_02591 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) S100761_02593 ENOG4105C38 Glycyl-tRNA synthetase beta subunit S100761_02594 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit S100761_02595 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) S100761_02597 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) S100761_02598 ENOG4105KG3 cytidine deaminase S100761_02599 ENOG4107YR5 Diacylglycerol kinase S100761_02600 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) S100761_02601 ENOG4105CTJ Metal Dependent Phosphohydrolase S100761_02603 ENOG4105C9A Phoh family S100761_02604 ENOG4105EI1 sporulation protein yqfd S100761_02605 ENOG41068P3 sporulation protein YqfC S100761_02607 ENOG4105DI5 UPF0365 protein S100761_02608 ENOG4105F7J membrane-bound serine protease S100761_02609 ENOG4105F7J membrane-bound serine protease S100761_02610 ENOG4105KTH gatB Yqey S100761_02613 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) S100761_02614 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) S100761_02615 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) S100761_02617 ENOG4105CFG Acts as a chaperone (By similarity) S100761_02618 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ S100761_02619 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) S100761_02620 ENOG4105CSA Coproporphyrinogen iii oxidase S100761_02621 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) S100761_02623 ENOG4108ZRV stage ii sporulation protein p S100761_02624 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) S100761_02625 ENOG41082YS Binds directly to 16S ribosomal RNA S100761_02626 ENOG4105TQK DNA polymerase iii, delta' subunit S100761_02628 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 S100761_02629 ENOG4108UK2 deaminase S100761_02630 ENOG4105KQC Competence protein S100761_02632 ENOG4108D32 Methyltransferase S100761_02634 ENOG4108WF2 Metal Dependent Phosphohydrolase S100761_02635 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) S100761_02636 ENOG410812S Rna-binding protein S100761_02637 ENOG4105E2X shikimate dehydrogenase S100761_02638 ENOG4105CQW ribosome biogenesis GTPase YqeH S100761_02639 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase S100761_02642 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase S100761_02643 ENOG41080BT SNARE associated Golgi S100761_02646 ENOG4105WFK nuclease S100761_02647 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) S100761_02648 ENOG4105C9Q fumarate hydratase class II S100761_02649 ENOG4107RSM transcriptional regulator S100761_02664 ENOG41064HX Suppressor of fused protein (SUFU) S100761_02667 ENOG4105FR7 XkdM protein, phage-like element PBSX S100761_02674 ENOG41090E6 transcriptional regulator MERR family S100761_02677 ENOG4105C37 (CBS) domain S100761_02680 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family S100761_02681 ENOG4105H3G oxidoreductase S100761_02682 ENOG4105PGM cation diffusion facilitator family transporter S100761_02685 ENOG4105KMT branched-chain amino acid S100761_02686 ENOG4108UMN azlc family S100761_02687 ENOG4108ZRZ Transcriptional regulator (AsnC family) S100761_02688 ENOG41067XF inhibitor S100761_02692 ENOG41064BW Protein of unknown function (DUF2568) S100761_02695 ENOG41075D4 Aminoglycoside 6-adenylyltransferase S100761_02696 ENOG4105EA8 2-Nitropropane dioxygenase S100761_02697 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) S100761_02700 ENOG4108MEK Metal-binding protein YodA S100761_02701 ENOG410904A RNA polymerase S100761_02702 ENOG4105CPC Aldo Keto reductase S100761_02704 ENOG4108KAM Transcriptional regulator S100761_02705 ENOG4105C7F AcnD-accessory protein PrpF S100761_02706 ENOG41083Q9 chitosanase S100761_02707 ENOG4105X5K response regulator receiver protein S100761_02708 ENOG4108VQT Alpha beta hydrolase fold protein S100761_02709 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein S100761_02710 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein S100761_02711 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase S100761_02713 ENOG4105PGS Spore coat protein S100761_02714 ENOG4105E2A Dehydrogenase S100761_02717 ENOG4105VUF Transcriptional regulator S100761_02719 ENOG4105DQ4 alcohol dehydrogenase S100761_02720 ENOG4108Z0Z intracellular protease Pfpi family S100761_02721 ENOG4108HKT sucrose-6-phosphate hydrolase S100761_02722 ENOG4105F3R pts system mannose fructose sorbose family iid S100761_02723 ENOG4105ETZ PTS System S100761_02724 ENOG4108IQ3 PTS system S100761_02725 ENOG4105YHU PTS system S100761_02726 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family S100761_02727 ENOG4105C85 amino acid S100761_02728 ENOG4105N14 lysine exporter protein LysE YggA S100761_02729 ENOG4108NGU Transcriptional regulator S100761_02730 ENOG4105JVQ RNA Polymerase S100761_02731 ENOG4108P49 AntiSigma factor S100761_02732 ENOG4105EXC Acyl-transferase S100761_02733 ENOG4105WDR S100761_02734 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) S100761_02735 ENOG41082JN Transcriptional regulator S100761_02739 ENOG4105TMB Formate nitrite transporter S100761_02740 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) S100761_02741 ENOG4108JB9 formate dehydrogenase S100761_02744 ENOG4105C28 cystathionine S100761_02747 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) S100761_02750 ENOG4107XRG penicillin-binding protein S100761_02751 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) S100761_02752 ENOG4105DBI uridine monophosphokinase S100761_02753 ENOG4105CFP Peptidase U32 S100761_02754 ENOG4105XYU peptidase (U32 family) S100761_02755 ENOG4108VQJ O-methyltransferase S100761_02756 ENOG4105HHA aminodeoxychorismate lyase S100761_02757 ENOG4105VPH UPF0473 protein S100761_02758 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) S100761_02759 ENOG4105VBH UPF0297 protein S100761_02760 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) S100761_02761 ENOG4105C02 permease S100761_02762 ENOG4105CDA abc transporter atp-binding protein S100761_02763 ENOG4105CT1 (ABC) transporter S100761_02764 ENOG4105EAD ABC transporter S100761_02765 ENOG4105DRP amino acid AbC transporter S100761_02767 ENOG41060CR S100761_02769 ENOG4105C7H Helicase, RecD TraA family S100761_02771 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) S100761_02772 ENOG4105C3J Cysteine desulfurase S100761_02774 ENOG4105D1H recombination factor protein RarA S100761_02775 ENOG4105CUZ uba thif-type nad fad binding protein S100761_02776 ENOG4105C9M aspartyl-trna synthetase S100761_02777 ENOG4105CUT histidyl-tRNA synthetase S100761_02779 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase S100761_02781 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) S100761_02782 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) S100761_02783 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) S100761_02784 ENOG41067VP Protein of unknown function (DUF1049) S100761_02785 ENOG4105NCW Trka-c domain protein S100761_02786 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) S100761_02788 ENOG4105CKP Polysaccharide Biosynthesis Protein S100761_02789 ENOG4108QG2 Membrane S100761_02790 ENOG4105NAP S100761_02791 ENOG4105VIE preprotein translocase, subunit YajC S100761_02792 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) S100761_02793 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) S100761_02794 ENOG41061AI Protein of unknown function (DUF2905) S100761_02795 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) S100761_02796 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) S100761_02798 ENOG4105IE8 Alpha-ketoglutarate permease S100761_02799 ENOG4105CK5 oxidoreductase S100761_02804 ENOG4105BZG amino acid carrier protein S100761_02805 ENOG4105CDY transcriptional regulatory protein S100761_02807 ENOG4106678 morphogenetic protein associated with SpoVID S100761_02808 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) S100761_02809 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase S100761_02810 ENOG4108IYU L-aspartate oxidase S100761_02813 ENOG4105CQC Prephenate dehydratase S100761_02814 ENOG41090I5 UPF0735 ACT domain-containing protein S100761_02815 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control S100761_02817 ENOG4105K46 50S ribosomal protein l27 S100761_02818 ENOG4105X36 (ribosomal) protein S100761_02819 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) S100761_02822 ENOG4107QMS site-determining protein S100761_02823 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) S100761_02824 ENOG4105YHC Rod shape-determining protein MreD S100761_02825 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) S100761_02826 ENOG4105DFF Rod shape-determining protein mreb S100761_02827 ENOG4105W5Q DNA repair protein (RadC S100761_02828 ENOG4108Z03 MAF-like protein S100761_02830 ENOG4106A3R peptidase S100761_02831 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase S100761_02832 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) S100761_02834 ENOG4106AR7 Spore coat protein S100761_02835 ENOG41068KH stage VI sporulation protein D S100761_02836 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase S100761_02837 ENOG4105D52 delta-aminolevulinic acid dehydratase S100761_02839 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) S100761_02841 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) S100761_02843 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) S100761_02844 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) S100761_02845 ENOG4108IUQ atp-dependent protease S100761_02846 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) S100761_02847 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation S100761_02849 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) S100761_02850 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) S100761_02851 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) S100761_02852 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) S100761_02853 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase S100761_02854 ENOG4108ZP8 Acetolactate synthase small subunit S100761_02855 ENOG4105C7K acetolactate synthase S100761_02857 ENOG4105I4A GCN5-related N-acetyltransferase S100761_02858 ENOG4107KM7 Heat induced stress protein YflT S100761_02860 ENOG4105M59 Phosphodiesterase, mj0936 family S100761_02861 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) S100761_02862 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) S100761_02863 ENOG4108XJQ germination protein S100761_02864 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) S100761_02865 ENOG41067TZ transcriptional regulator, MarR family S100761_02866 ENOG4105PFC Transcriptional regulator S100761_02868 ENOG4105E33 succinate dehydrogenase S100761_02870 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit S100761_02872 ENOG4105CFH Aspartokinase S100761_02873 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) S100761_02874 ENOG4105K63 Thioredoxin S100761_02875 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) S100761_02877 ENOG4105C10 Electron transfer flavoprotein S100761_02878 ENOG4105BZJ Electron transfer flavoprotein S100761_02879 ENOG41060WC Enoyl-CoA hydratase S100761_02880 ENOG4107Z3H Transcriptional regulator, TetR family S100761_02881 ENOG4105CEY Amp-dependent synthetase and ligase S100761_02883 ENOG4105C98 muts2 protein S100761_02884 ENOG4105DCG PHP domain protein S100761_02887 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) S100761_02888 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) S100761_02889 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) S100761_02890 ENOG4108RWN rrna methyltransferase S100761_02891 ENOG41067MF small acid-soluble spore protein S100761_02893 ENOG4105CQB FAD linked oxidase domain protein S100761_02894 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) S100761_02897 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) S100761_02898 ENOG4105DRS transport system, permease S100761_02901 ENOG4108MDK Dehydrogenase S100761_02903 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase S100761_02904 ENOG4105EF1 ribulokinase S100761_02906 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase S100761_02907 ENOG4105CN9 Peptidase m42 family protein S100761_02909 ENOG410696E Membrane S100761_02910 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) S100761_02911 ENOG4105VJV 50s ribosomal protein L35 S100761_02912 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) S100761_02914 ENOG41067MG lrgb family S100761_02916 ENOG4105DY9 regulatoR S100761_02917 ENOG4108HRK Histidine kinase S100761_02918 ENOG4105U0R haloacid dehalogenase-like hydrolase S100761_02919 ENOG4105C22 threonyL-tRNA synthetase S100761_02921 ENOG4108TDW sporulation protein YtxC S100761_02925 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) S100761_02926 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) S100761_02927 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase S100761_02928 ENOG4105KVH Transcriptional regulator S100761_02929 ENOG4105KVH Transcriptional regulator S100761_02930 ENOG4105F27 Major Facilitator S100761_02931 ENOG4105CV8 reductase S100761_02932 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) S100761_02934 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) S100761_02935 ENOG4105C2M dna polymerase I S100761_02936 ENOG4105BZU Histidine kinase S100761_02937 ENOG4105DPZ Two component transcriptional regulator (Winged helix family S100761_02938 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) S100761_02939 ENOG4108HMX isocitrate dehydrogenase (NADP) S100761_02940 ENOG4105BZN citrate synthase S100761_02942 ENOG4108REF Sporulation integral membrane protein ytvi S100761_02943 ENOG4108REF Sporulation integral membrane protein ytvi S100761_02944 ENOG4105FS0 cytoplasmic membrane protein S100761_02945 ENOG4105CA9 Pyruvate kinase S100761_02946 ENOG4105CTQ phosphohexokinase S100761_02948 ENOG4108IEY Carboxyl transferase domain S100761_02949 ENOG4105C6K Malic enzyme S100761_02950 ENOG4105C0B DNA polymerase III (alpha subunit) S100761_02951 ENOG4105VV2 S100761_02953 ENOG4106EVM S100761_02954 ENOG4105SFS phosphoesterase RecJ domain protein S100761_02957 ENOG4105E8R UPF0173 metal-dependent hydrolase S100761_02960 ENOG4105CH7 arginosuccinase S100761_02961 ENOG4105CDH Citrulline--aspartate ligase S100761_02962 ENOG4105EPU Molybdenum cofactor synthesis domain protein S100761_02963 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) S100761_02966 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) S100761_02967 ENOG4105KBJ sporulation protein ytfj S100761_02969 ENOG4105VK3 rdd domain containing protein S100761_02970 ENOG4105D07 Signal peptide peptidase, SppA S100761_02971 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) S100761_02972 ENOG4105EFZ amidohydrolase S100761_02973 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) S100761_02980 ENOG4105U5Y Transcriptional regulator S100761_02982 ENOG4105BZU Histidine kinase S100761_02983 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) S100761_02985 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) S100761_02987 ENOG4105F1V Acetoin utilization protein S100761_02988 ENOG4105W87 Cbs domain S100761_02989 ENOG4105DGU Histone deacetylase S100761_02990 ENOG4105ER2 Ompa motb domain protein S100761_02991 ENOG4107R0U MotA TolQ exbB proton channel S100761_02992 ENOG4105ETE Transcriptional regulator (LacI family S100761_02993 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase S100761_02997 ENOG4105DFU Cell wall formation (By similarity) S100761_02999 ENOG4108VDD TRNA binding domain protein S100761_03002 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ S100761_03005 ENOG4105C6K Malic enzyme S100761_03006 ENOG4105C8F Beta-lactamase domain protein S100761_03007 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) S100761_03009 ENOG4108V15 phosphotransferase enzyme family S100761_03010 ENOG4108IUM Glycogen debranching enzyme S100761_03013 ENOG4107F58 2'-5' rna ligase S100761_03014 ENOG4105C6T cysteine synthase S100761_03015 ENOG4107QSE Dipeptidase S100761_03016 ENOG4105C7N Xanthine uracil vitamin C permease S100761_03019 ENOG4105YW5 deoR family transcriptional regulator S100761_03022 ENOG4105CBX hi0933 family S100761_03023 ENOG4105C94 Transporter S100761_03025 ENOG4105MU9 integral membrane protein S100761_03026 ENOG4105DDC Oxidoreductase domain protein S100761_03028 ENOG4105F5H Glycosyl Hydrolase Family 88 S100761_03030 ENOG41075H3 AraC family transcriptional regulator S100761_03032 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component S100761_03034 ENOG4106A3M Cytochrome p-450 S100761_03035 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) S100761_03037 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) S100761_03038 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) S100761_03040 ENOG4105NTD Inherit from COG: Hydrolase S100761_03043 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component S100761_03044 ENOG4105I1K ABC transporter S100761_03046 ENOG41085GJ domain protein S100761_03047 ENOG4105C8T Leucyl-tRNA synthetase S100761_03049 ENOG4105BZU Histidine kinase S100761_03050 ENOG410605W Major Facilitator S100761_03051 ENOG4106UBQ S100761_03053 ENOG4105C19 ABC transporter S100761_03054 ENOG4105EWM Histidine kinase S100761_03056 ENOG4107R34 abc transporter permease protein S100761_03057 ENOG4105C19 ABC transporter S100761_03060 ENOG4105DVE abc transporter atp-binding protein S100761_03061 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family S100761_03064 ENOG4105N5T Radical SAM Protein S100761_03067 ENOG4105E8V Alpha Beta Hydrolase Fold protein S100761_03068 ENOG4108Z0R Transferase S100761_03069 ENOG4105C85 amino acid S100761_03070 ENOG4105CAQ asparagine synthetase S100761_03071 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP S100761_03072 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase S100761_03075 ENOG4105D2X ABC transporter substrate-binding protein S100761_03077 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component S100761_03080 ENOG4108RMU ferritin dps family protein S100761_03083 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) S100761_03084 ENOG4108V2W Carbonate dehydratase S100761_03089 ENOG4105CC5 ABC transporter S100761_03090 ENOG4105CC5 ABC transporter S100761_03091 ENOG4105DIK (ABC) transporter S100761_03092 ENOG4105DSE periplasmic solute binding protein S100761_03093 ENOG4105DTQ mandelate racemase muconate lactonizing S100761_03094 ENOG4105CEY Amp-dependent synthetase and ligase S100761_03095 ENOG4108IPT Naphthoate synthase S100761_03096 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) S100761_03097 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) S100761_03098 ENOG4105E4F Isochorismate synthase S100761_03102 ENOG4108IAJ Nad-dependent epimerase dehydratase S100761_03103 ENOG4107SBE Glycosyl transferase (Group 1 S100761_03106 ENOG4107SBE Glycosyl transferase (Group 1 S100761_03107 ENOG4108KS4 Spore coat protein S100761_03110 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) S100761_03112 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) S100761_03138 ENOG4105N67 Proton-coupled thiamine transporter YuaJ S100761_03139 ENOG4105VRR gCN5-related N-acetyltransferase S100761_03140 ENOG4105DZ6 Band 7 protein S100761_03142 ENOG4106DF1 S100761_03143 ENOG4108VNY MOSC domain protein S100761_03144 ENOG4108JB8 alcohol dehydrogenase S100761_03145 ENOG4105C26 Dehydrogenase S100761_03146 ENOG4105TRT Transcriptional regulator S100761_03149 ENOG4105CZN Potassium uptake protein S100761_03150 ENOG4107I77 yiaA/B two helix domain S100761_03151 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj S100761_03155 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) S100761_03157 ENOG4105EE0 oxidoreductase S100761_03158 ENOG4105DKG l-rhamnose isomerase S100761_03159 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) S100761_03160 ENOG4105DET Rhamnulokinase S100761_03161 ENOG4105E98 transcriptional regulator DeoR family S100761_03163 ENOG4105C8Q Methyl-accepting chemotaxis S100761_03164 ENOG4105C8Q Methyl-accepting chemotaxis S100761_03165 ENOG4105C8Q Methyl-accepting chemotaxis S100761_03166 ENOG4105C8Q Methyl-accepting chemotaxis S100761_03169 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme S100761_03171 ENOG4105C37 (CBS) domain S100761_03174 ENOG4107PBV potassium channel S100761_03175 ENOG4107PBV potassium channel S100761_03178 ENOG4107QYV phosphohexose isomerase S100761_03180 ENOG4107QW4 alcohol dehydrogenase S100761_03181 ENOG4105WG9 Conserved Protein S100761_03183 ENOG4105CHM Aminotransferase S100761_03184 ENOG4108ZB6 transcriptional regulator AsnC family S100761_03185 ENOG4108MUZ hydrolase S100761_03187 ENOG4105C87 Aminotransferase class I and II S100761_03188 ENOG4108HGU Histidine kinase S100761_03189 ENOG4105Y38 Kinase-associated protein B S100761_03193 ENOG4105BZ4 penicillin-binding protein S100761_03194 ENOG4105KIR Thiol-disulfide oxidoreductase dcc S100761_03197 ENOG4108MRH transcriptional regulatory protein S100761_03198 ENOG4105DIH basic membrane S100761_03199 ENOG4108JQ9 ABC transporter S100761_03200 ENOG4105UIB (ABC) transporter S100761_03204 ENOG4105D65 subunit l S100761_03205 ENOG4105HC0 Na H antiporter S100761_03206 ENOG4108ZE9 Monovalent cation H antiporter subunit C S100761_03207 ENOG4108JPZ Monovalent cation H antiporter subunit D S100761_03208 ENOG4105SC1 monovalent cation H antiporter subunit E S100761_03210 ENOG4105KJM monovalent cation h antiporter subunit g S100761_03211 ENOG4105KA0 thioesterase Superfamily protein S100761_03213 ENOG4105BZU Histidine kinase S100761_03219 ENOG4105D58 Diguanylate phosphodiesterase S100761_03220 ENOG4105DAP Nicotinate phosphoribosyltransferase S100761_03225 ENOG4105C02 permease S100761_03228 ENOG410904N short-chain dehydrogenase reductase S100761_03235 ENOG4108K8K Transcriptional regulator S100761_03236 ENOG4105DCF alanine dehydrogenase S100761_03238 ENOG4105WQT MbtH domain protein S100761_03239 ENOG4105CEY Amp-dependent synthetase and ligase S100761_03240 ENOG4105WQI isochorismatase S100761_03241 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase S100761_03242 ENOG4105E4F Isochorismate synthase S100761_03243 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase S100761_03244 ENOG4105NIV Esterase S100761_03248 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) S100761_03250 ENOG41069ER domain protein S100761_03252 ENOG4105CEP NADH dehydrogenase S100761_03253 ENOG4105CAY ferredoxin--nadp reductase S100761_03257 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 S100761_03259 ENOG4108YX9 iron--sulfur cluster insertion protein erpA S100761_03262 ENOG4105ZKE UPF0349 protein S100761_03265 ENOG41083MR nifu domain-containing protein S100761_03266 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein S100761_03267 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) S100761_03268 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) S100761_03269 ENOG4105D6E homoserine dehydrogenase S100761_03271 ENOG4108W5N phosphatidylglycerophosphatase a S100761_03272 ENOG4105D4U had-superfamily hydrolase, subfamily iia S100761_03274 ENOG4105MMD transcriptional regulator S100761_03275 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) S100761_03276 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) S100761_03277 ENOG4105FAA peptidase M23 S100761_03278 ENOG4108YTE sporulation protein YunB S100761_03279 ENOG4105KZD Domain of unknown function (DUF1805) S100761_03280 ENOG4107R8B 5'-nucleotidase S100761_03282 ENOG4105I3N Conserved Protein S100761_03284 ENOG4105CD3 dihydroorotase S100761_03285 ENOG4105G9B Transcriptional regulator S100761_03288 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) S100761_03289 ENOG4105VT2 5-hydroxyisourate hydrolase S100761_03291 ENOG4107YV9 domain protein S100761_03292 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding S100761_03295 ENOG4105XRQ Xanthine dehydrogenase accessory factor S100761_03296 ENOG4105C5R Aminotransferase S100761_03298 ENOG4108K8S endonuclease I S100761_03299 ENOG4108IJ9 (ABC) transporter S100761_03300 ENOG4105FDP GntR family transcriptional regulator S100761_03301 ENOG4108KPW sugar kinase S100761_03302 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component S100761_03303 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component S100761_03304 ENOG4105XN3 extracellular solute-binding protein family 1 S100761_03305 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine S100761_03306 ENOG4105PKS Excinuclease abc c subunit domain protein S100761_03307 ENOG4107VFR oxidoreductase S100761_03310 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase S100761_03311 ENOG4105NPE arsR family transcriptional regulator S100761_03312 ENOG4105DIW FeS assembly protein SUFB S100761_03313 ENOG4108UNV SUF system FeS assembly protein, NifU family S100761_03314 ENOG4105C9B Cysteine desulfurase S100761_03315 ENOG4105JRK feS assembly protein SufD S100761_03316 ENOG4105C3K feS assembly ATPase SufC S100761_03318 ENOG4105D01 (LipO)protein S100761_03319 ENOG4108UMI ABC transporter, permease S100761_03320 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) S100761_03325 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) S100761_03326 ENOG41080E8 Transcriptional regulator, Spx MgsR family S100761_03327 ENOG4105C1G acyl-Coa dehydrogenase S100761_03328 ENOG4105CHU acetyl-coa acetyltransferase S100761_03334 ENOG41067TZ transcriptional regulator, MarR family S100761_03335 ENOG4105C0R drug resistance transporter emrb qaca subfamily S100761_03336 ENOG4105MDS 4-oxalocrotonate tautomerase S100761_03338 ENOG4105EGI Transcriptional regulator S100761_03340 ENOG4105E0A ABC, transporter S100761_03353 ENOG4105E1F short-chain dehydrogenase reductase S100761_03354 ENOG4105HUF DNA protection during starvation protein S100761_03355 ENOG4105C0H protease S100761_03357 ENOG4105F3H Histidine kinase S100761_03358 ENOG41067SE Tetr family transcriptional regulator S100761_03359 ENOG4105C9Q fumarate hydratase class II S100761_03364 ENOG4105WH1 Two component transcriptional regulator luxr family S100761_03365 ENOG4105ENE Histidine kinase S100761_03368 ENOG41087YS Phage shock protein A S100761_03371 ENOG4108WBT adenosyltransferase S100761_03372 ENOG4105E0A ABC, transporter S100761_03373 ENOG4105EHG Permease protein S100761_03374 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) S100761_03375 ENOG4105EWI Short-chain dehydrogenase reductase Sdr S100761_03376 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein S100761_03378 ENOG4105DPZ Two component transcriptional regulator (Winged helix family S100761_03380 ENOG4106DF4 Sigma-70, region 4 S100761_03382 ENOG4105F0F Oxalate decarboxylase S100761_03384 ENOG4107RBB ABC transporter, permease S100761_03385 ENOG4105C19 ABC transporter S100761_03386 ENOG4108WMK Efflux transporter RND family MFP subunit S100761_03387 ENOG4105E0A ABC, transporter S100761_03388 ENOG4105EHG Permease protein S100761_03389 ENOG4105DQ5 transport system permease protein S100761_03392 ENOG4105D5Q Arginine ornithine antiporter S100761_03394 ENOG4107K5X Membrane-bound metal-dependent hydrolase S100761_03395 ENOG4107QZ2 Sulfatase S100761_03396 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family S100761_03397 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein S100761_03398 ENOG4105E0C molybdate abc transporter S100761_03401 ENOG4105EEQ Na H antiporter S100761_03402 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) S100761_03403 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) S100761_03404 ENOG4105EEM helicase S100761_03406 ENOG4105EN6 Membrane S100761_03408 ENOG4107ZQN disulfide bond S100761_03409 ENOG4105C59 p-type ATPase S100761_03410 ENOG4105C59 p-type ATPase S100761_03411 ENOG410681U heavy metal transport detoxification protein S100761_03412 ENOG4105VPX protein, conserved in bacteria S100761_03413 ENOG4105D9R oxidoreductase S100761_03414 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) S100761_03415 ENOG4105ME7 Membrane S100761_03416 ENOG4105RXJ S100761_03417 ENOG4105KPY Small multidrug resistance protein S100761_03418 ENOG4105KBX Transcriptional regulator, TetR family S100761_03419 ENOG4105EWI Short-chain dehydrogenase reductase Sdr S100761_03420 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) S100761_03421 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) S100761_03423 ENOG4105XZU Preprotein translocase, subunit SecG S100761_03428 ENOG4105KVH Transcriptional regulator S100761_03429 ENOG4105C8Q Methyl-accepting chemotaxis S100761_03430 ENOG4105R40 Glycine betaine carnitine choline S100761_03431 ENOG4108HQR Glycine betaine S100761_03432 ENOG4105E90 ABC transporter S100761_03433 ENOG4108IJ8 ABC transporter S100761_03434 ENOG4107HG4 Transcriptional regulator S100761_03435 ENOG4105R40 Glycine betaine carnitine choline S100761_03436 ENOG4108HQR Glycine betaine S100761_03437 ENOG4105E90 ABC transporter S100761_03438 ENOG4108IJ8 ABC transporter S100761_03439 ENOG4107HG4 Transcriptional regulator S100761_03440 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein S100761_03441 ENOG4108QCI YvbH-like oligomerisation region S100761_03443 ENOG4105T65 Membrane-associated protein S100761_03444 ENOG4108W0I acetyltransferase S100761_03445 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) S100761_03446 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) S100761_03447 ENOG4105CP7 Triose-phosphate isomerase S100761_03448 ENOG4105BZA Phosphoglycerate kinase S100761_03449 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase S100761_03452 ENOG4105CMD Transcriptional regulator, GntR family S100761_03453 ENOG4105DEN Luciferase family S100761_03454 ENOG4105GZI Transcriptional regulator S100761_03455 ENOG4107RT3 EamA-like transporter family S100761_03457 ENOG4105VRS hydrolase family 18 S100761_03458 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) S100761_03459 ENOG4107QR9 Iron-sulfur cluster binding protein S100761_03460 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) S100761_03464 ENOG4105BZU Histidine kinase S100761_03465 ENOG4105KCT ABC transporter S100761_03466 ENOG4108M15 ABC transporter S100761_03468 ENOG4107R6F Alpha Beta Hydrolase Fold protein S100761_03469 ENOG4108MJI response regulator S100761_03472 ENOG4105EG2 ABC transporter, permease S100761_03474 ENOG4107FKK extracellular solute-binding protein family 1 S100761_03476 ENOG4105JXH GntR family transcriptional regulator S100761_03477 ENOG4105DAA L-lactate S100761_03478 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) S100761_03480 ENOG4108ZPC Polysaccharide pyruvyl transferase S100761_03481 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase S100761_03482 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family S100761_03483 ENOG4105D3Q Sugar transferase S100761_03485 ENOG4105K64 Glycosyl transferase, family 2 S100761_03487 ENOG4107QRS glycosyltransferase group 2 family protein S100761_03488 ENOG41068W6 Capsular polysaccharide biosynthesis protein S100761_03489 ENOG4108KMV Glycosyl transferase (Group 1 S100761_03490 ENOG4105K64 Glycosyl transferase, family 2 S100761_03491 ENOG4108PQP glycosyl transferase group 1 S100761_03493 ENOG4108QV3 biosynthesis protein S100761_03494 ENOG4105HTX biosynthesis protein S100761_03496 ENOG4105EBR Carboxylesterase S100761_03498 ENOG4105PY6 Phenolic acid decarboxylase S100761_03499 ENOG4105NI3 Protein of unknown function (DUF3237) S100761_03501 ENOG4105FQP Beta-lactamase S100761_03502 ENOG4105EDQ levansucrase EC 2.4.1.10 S100761_03503 ENOG4108HKT sucrose-6-phosphate hydrolase S100761_03504 ENOG4107QTZ amino acid S100761_03510 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) S100761_03511 ENOG4107URF beta-phospho-glucomutase S100761_03512 ENOG4105CG3 alpha amylase, catalytic region S100761_03515 ENOG4105EG2 ABC transporter, permease S100761_03516 ENOG4105D56 permease protein S100761_03517 ENOG4107FKK extracellular solute-binding protein family 1 S100761_03518 ENOG4108IUK alpha amylase, catalytic S100761_03519 ENOG4105FKQ transcriptional regulator S100761_03520 ENOG4108URH decarboxylase S100761_03521 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain S100761_03522 ENOG4105CHH sulfate transporter S100761_03523 ENOG4108V2W Carbonate dehydratase S100761_03524 ENOG4105C5I Dehydrogenase S100761_03526 ENOG4105C19 ABC transporter S100761_03527 ENOG4105EWM Histidine kinase S100761_03529 ENOG4107A6P S100761_03530 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase S100761_03531 ENOG4105KRI phosphocarrier protein (HPr S100761_03532 ENOG4105CIE May be required for sporulation (By similarity) S100761_03533 ENOG4105CHW UPF0052 protein S100761_03534 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) S100761_03535 ENOG4108Z4K mutator MutT protein S100761_03536 ENOG4105C3M thioredoxin reductase S100761_03539 ENOG4105BZ1 (ABC) transporter S100761_03541 ENOG4106FGC S100761_03543 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase S100761_03544 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) S100761_03545 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase S100761_03546 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) S100761_03547 ENOG4105ECC imidazole-glycerol-phosphate dehydratase S100761_03548 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) S100761_03549 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) S100761_03550 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) S100761_03552 ENOG4108E16 pectate lyase S100761_03553 ENOG4108S4C acetyltransferase S100761_03554 ENOG4107XGZ Hydrolase S100761_03555 ENOG4105HKU nucleoside recognition domain-containing protein S100761_03556 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) S100761_03557 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) S100761_03558 ENOG4105CE4 GlcNAc 6-P deacetylase S100761_03559 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) S100761_03560 ENOG4105FDP GntR family transcriptional regulator S100761_03561 ENOG41088CQ domain protein S100761_03563 ENOG4106A3M Cytochrome p-450 S100761_03564 ENOG410625E S100761_03567 ENOG41086DT Membrane protein of unknown function S100761_03568 ENOG41067S9 phage shock protein C, PspC S100761_03569 ENOG4108PY7 S100761_03572 ENOG4105I03 Flagellin S100761_03573 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) S100761_03574 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) S100761_03575 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) S100761_03578 ENOG4105MKU Transcriptional regulator S100761_03582 ENOG4105CN1 protease S100761_03583 ENOG4105CRP Part of the ABC transporter FtsEX involved in S100761_03584 ENOG4105CAK Cell division ATP-binding protein ftsE S100761_03587 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) S100761_03589 ENOG4105MS2 ribosomal subunit Interface protein S100761_03592 ENOG4105MQ3 flagellar protein FliS S100761_03593 ENOG4107RT6 flagellar hook-associated S100761_03594 ENOG41083S7 flagellar protein FlaG S100761_03595 ENOG4105I03 Flagellin S100761_03596 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) S100761_03597 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) S100761_03598 ENOG4105MKD S100761_03599 ENOG4105DTJ flagellar hook-associated protein S100761_03600 ENOG4105E1Q flagellar hook-associated protein S100761_03603 ENOG4105RU3 S100761_03604 ENOG41081UC Inherit from COG: Competence protein S100761_03608 ENOG4105WH1 Two component transcriptional regulator luxr family S100761_03609 ENOG4105BZU Histidine kinase S100761_03610 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein S100761_03611 ENOG4108KGH TRANSCRIPTIONal S100761_03618 ENOG4108RDQ ABC transporter S100761_03620 ENOG4105ESV Glycosyl transferase, family 4 S100761_03621 ENOG4107EF8 Glycosyl transferase (Group 1 S100761_03624 ENOG4105QZI O-Antigen Polymerase S100761_03626 ENOG4105C6Y Udp-glucose 6-dehydrogenase S100761_03627 ENOG4107RA4 Glycosyl transferase (Group 1 S100761_03628 ENOG4105PSV Polysaccharide Biosynthesis Protein S100761_03629 ENOG4105D3Q Sugar transferase S100761_03630 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase S100761_03631 ENOG4105JFG SpoIID LytB domain protein S100761_03633 ENOG4108KGH TRANSCRIPTIONal S100761_03634 ENOG4108KGH TRANSCRIPTIONal S100761_03635 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase S100761_03636 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase S100761_03638 ENOG4105EY8 ABC transporter S100761_03642 ENOG4107SJB teichoic acid biosynthesis S100761_03643 ENOG4107SJB teichoic acid biosynthesis S100761_03644 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase S100761_03646 ENOG4107RZX Teichoic acid biosynthesis protein S100761_03648 ENOG4105DG6 mannose-6-phosphate isomerase S100761_03651 ENOG4108NHD germination protein S100761_03652 ENOG4105C54 Major Facilitator superfamily S100761_03653 ENOG4108KGH TRANSCRIPTIONal S100761_03654 ENOG4105J7I hydrolase S100761_03655 ENOG4105DQ6 Transposase S100761_03657 ENOG4105K4H Nlp p60 protein S100761_03659 ENOG4105PNM synthesis protein S100761_03661 ENOG4105N98 Capsule biosynthesis protein capB S100761_03662 ENOG4105ETE Transcriptional regulator (LacI family S100761_03663 ENOG4108RVA ribokinase S100761_03664 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) S100761_03665 ENOG4105C2J ABC transporter S100761_03666 ENOG4105CNN ABC, transporter S100761_03667 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator S100761_03670 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein S100761_03671 ENOG4107FQX Alpha-acetolactate decarboxylase S100761_03673 ENOG4107RSM transcriptional regulator S100761_03676 ENOG4106UIA S100761_03676 ENOG4106UIA S100761_03679 ENOG4107XC4 flavin reductase domain protein, FMN-binding S100761_03681 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) S100761_03683 ENOG4105CAH Chromate S100761_03684 ENOG4105FGV Chromate S100761_03686 ENOG4108WS4 fmn reductase S100761_03687 ENOG4107V2S Transcriptional regulator S100761_03688 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) S100761_03697 ENOG4108XI2 Domain of unknown function (DUF1963) S100761_03698 ENOG4105C6Y Udp-glucose 6-dehydrogenase S100761_03699 ENOG4108RB3 Capsular polysaccharide biosynthesis protein S100761_03700 ENOG4107YJ4 chain length determinant protein S100761_03701 ENOG4105HTX biosynthesis protein S100761_03703 ENOG4105KBK Zinc finger, swim domain protein S100761_03704 ENOG4105C0D helicase S100761_03705 ENOG410667J hydrolase S100761_03706 ENOG4105E98 transcriptional regulator DeoR family S100761_03707 ENOG4105Z8H single-stranded DNA-binding protein S100761_03713 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) S100761_03714 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) S100761_03716 ENOG4105CGA flagellar basal-body rod protein FlgG S100761_03718 ENOG4105DFF Rod shape-determining protein mreb S100761_03719 ENOG4105MT0 Sporulation transcriptional regulator spoiiid S100761_03720 ENOG4107MII Sugar-specific transcriptional regulator TrmB S100761_03721 ENOG4105CZM Major Facilitator S100761_03722 ENOG4108M26 parallel beta-helix repeat protein S100761_03723 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease S100761_03724 ENOG41080V3 Major Facilitator superfamily S100761_03725 ENOG4105D3W isochorismatase S100761_03726 ENOG4107P26 S100761_03727 ENOG4105BZU Histidine kinase S100761_03729 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase S100761_03731 ENOG4105FRN stage II sporulation protein S100761_03732 ENOG4107TCE N-acetyltransferase S100761_03736 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) S100761_03737 ENOG4107TXC Transcriptional regulator S100761_03738 ENOG4106BRK S100761_03739 ENOG4108RYK Nad-dependent epimerase dehydratase S100761_03740 ENOG4108Z40 Transcriptional regulator S100761_03741 ENOG4105CQM Urea amidohydrolase subunit alpha S100761_03742 ENOG4105KI2 Urea amidohydrolase subunit beta S100761_03743 ENOG4108YZ9 Urea amidohydrolase subunit gamma S100761_03748 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) S100761_03750 ENOG4108TF4 von Willebrand factor, type A S100761_03752 ENOG4105JFG SpoIID LytB domain protein S100761_03753 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) S100761_03755 ENOG4106778 Protein of unknown function (DUF1146) S100761_03757 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) S100761_03758 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) S100761_03759 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) S100761_03760 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) S100761_03764 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) S100761_03766 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) S100761_03767 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) S100761_03768 ENOG4108UIC UPF0340 protein S100761_03769 ENOG4108YZG isomerase S100761_03770 ENOG4107WAU Protein tyrosine phosphatase S100761_03771 ENOG410815N Probably functions as a manganese efflux pump (By similarity) S100761_03772 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) S100761_03774 ENOG4108ZXQ stage ii sporulation protein r S100761_03777 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) S100761_03778 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) S100761_03779 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase S100761_03781 ENOG4107TT2 Auxin Efflux Carrier S100761_03782 ENOG4105C6K Malic enzyme S100761_03783 ENOG4107104 thymidine kinase S100761_03784 ENOG41082DI 50s ribosomal protein l31 S100761_03785 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) S100761_03786 ENOG4105CBT Fructose-1,6-bisphosphatase S100761_03787 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) S100761_03788 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway S100761_03789 ENOG4105D2N Aldolase S100761_03790 ENOG410812K response regulator receiver protein S100761_03792 ENOG4105DQ6 Transposase S100761_03794 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) S100761_03796 ENOG4105C1G acyl-Coa dehydrogenase S100761_03797 ENOG4105DF6 Fe-S oxidoreductase S100761_03799 ENOG4105E5J UV damage endonuclease S100761_03801 ENOG4105NAE bifunctional deaminase-reductase domain protein S100761_03802 ENOG4105BZ1 (ABC) transporter S100761_03803 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) S100761_03805 ENOG4105R3A Nitrate reductase S100761_03806 ENOG4108IUE nitrate reductase beta subunit S100761_03810 ENOG4107V6Q Cyclic nucleotide-binding domain S100761_03812 ENOG4105C75 arginyL-tRNA synthetase S100761_03813 ENOG410684U Domain of unknown function (DUF1934) S100761_03815 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E S100761_03824 ENOG4107JM4 Tetratricopeptide repeat S100761_03826 ENOG4108UIN ybak prolyl-trna synthetase associated region S100761_03827 ENOG4105CYW agmatinase S100761_03828 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) S100761_03829 ENOG4105BZ4 penicillin-binding protein S100761_03830 ENOG4108XFG YwhD family S100761_03831 ENOG4108Z4T Peptidase M50 S100761_03832 ENOG41069HH 4-oxalocrotonate tautomerase S100761_03833 ENOG41067TZ transcriptional regulator, MarR family S100761_03834 ENOG4105C22 threonyL-tRNA synthetase S100761_03836 ENOG4105C57 major facilitator superfamily S100761_03837 ENOG41062ES Transcriptional regulator S100761_03839 ENOG4105DCI Phosphohydrolase S100761_03841 ENOG4108VCI transcription factor, rsfa family S100761_03842 ENOG4108RNG Permease of the drug metabolite transporter S100761_03843 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) S100761_03844 ENOG4105DUM transcriptional regulator, lysR family S100761_03845 ENOG4108IJ2 phosphate acetyltransferase S100761_03848 ENOG4105CHM Aminotransferase S100761_03850 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase S100761_03851 ENOG4105CHR reductase S100761_03852 ENOG4106CHD Bacilysin biosynthesis protein bacB S100761_03853 ENOG41061WN bacilysin biosynthesis protein S100761_03854 ENOG4105FCW Major Facilitator superfamily S100761_03857 ENOG4105C26 Dehydrogenase S100761_03858 ENOG4105D82 Glutamate dehydrogenase S100761_03860 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase S100761_03861 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase S100761_03862 ENOG4105C1B dTDP-glucose 4-6-dehydratase S100761_03863 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) S100761_03864 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG S100761_03865 ENOG4107TY6 Acylneuraminate cytidylyltransferase S100761_03867 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD S100761_03868 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase S100761_03875 ENOG4105C26 Dehydrogenase S100761_03876 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) S100761_03877 ENOG4108RJ9 Glycosyl transferase, family 2 S100761_03878 ENOG4105DWF phosphomethylpyrimidine kinase S100761_03881 ENOG4105C5Y PTS System S100761_03882 ENOG4108QTI )-transporter S100761_03885 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin S100761_03886 ENOG4105DEN Luciferase family S100761_03887 ENOG4108DBC nitroreductase S100761_03891 ENOG41060D1 Quinol oxidase S100761_03892 ENOG4105CCU oxidase (Subunit III) S100761_03893 ENOG4105BZ9 Cytochrome C oxidase, subunit I S100761_03894 ENOG4105E2S oxidase) subunit II S100761_03895 ENOG4107BMA Transglycosylase associated protein S100761_03897 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) S100761_03898 ENOG4105WH5 Teichoic acid glycosylation protein S100761_03903 ENOG4107ZXU DSBA oxidoreductase S100761_03904 ENOG4105DBE peroxidase S100761_03905 ENOG410650H (LipO)protein S100761_03906 ENOG4107SJW iron permease, FTR1 S100761_03907 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) S100761_03909 ENOG4105CMU LysR family (Transcriptional regulator S100761_03910 ENOG4105VAW lrga family S100761_03911 ENOG41067MG lrgb family S100761_03912 ENOG4105D8G Major Facilitator superfamily S100761_03914 ENOG4105DR4 Methyltransferase S100761_03916 ENOG4108YV3 Protein of unknown function (DUF2711) S100761_03917 ENOG4105CK1 PTS System S100761_03918 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin S100761_03919 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin S100761_03922 ENOG4105X1N Glycosyl transferase family 8 S100761_03924 ENOG4105GVJ transcriptional regulator S100761_03925 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) S100761_03926 ENOG4105IIU Aminopeptidase S100761_03928 ENOG4105DQ6 Transposase S100761_03930 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase S100761_03932 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) S100761_03933 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein S100761_03935 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD S100761_03936 ENOG4108VHC Short-chain dehydrogenase reductase Sdr S100761_03937 ENOG4105CM2 brancheD-chain amino acid aminotransferase S100761_03938 ENOG4105F8D glycoside hydrolase family 4 S100761_03939 ENOG4105VCP PTS System S100761_03940 ENOG4105CK1 PTS System S100761_03941 ENOG4105VZJ PTS System S100761_03942 ENOG4105EMD TRANSCRIPTIONal S100761_03944 ENOG4108VX5 3-methyladenine DNA glycosylase S100761_03945 ENOG4105CH6 catalase S100761_03948 ENOG4105DA5 (ABC) transporter S100761_03949 ENOG41069JR S100761_03953 ENOG4105ETS cytosine purines uracil thiamine allantoin S100761_03954 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) S100761_03955 ENOG4108JJ8 (ABC) transporter S100761_03956 ENOG4108JJ9 ABC, transporter S100761_03957 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii S100761_03958 ENOG4105C4M (Ubiquinol oxidase) subunit I S100761_03959 ENOG4105D2K citrate carrier protein S100761_03962 ENOG4107BJW polysaccharide deacetylase S100761_03966 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) S100761_03968 ENOG4105CMR udp-glucose 4-epimerase S100761_03970 ENOG4105BZU Histidine kinase S100761_03971 ENOG4105WH1 Two component transcriptional regulator luxr family S100761_03972 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) S100761_03977 ENOG4105DTD Dehydrogenase S100761_03978 ENOG4108IIH CoA-transferase subunit B S100761_03979 ENOG4105D6N CoA-transferase, subunit a S100761_03980 ENOG4105CY2 Citrate transporter S100761_03981 ENOG4105DHI Methyltransferase S100761_03985 ENOG4105CH6 catalase S100761_03986 ENOG4105D4T Citrate transporter S100761_03987 ENOG4108RZ2 Glycoside hydrolase family 16 S100761_03988 ENOG4105CID antiterminator S100761_03990 ENOG4105DEU major facilitator superfamily S100761_03991 ENOG4105C1J atp-dependent rna helicase S100761_03992 ENOG4107TDE lipolytic protein G-D-S-L family S100761_04017 ENOG4107YZX Universal stress protein S100761_04018 ENOG4105CS2 ec 3.2.1.21 S100761_04019 ENOG4105C5Y PTS System S100761_04021 ENOG4107EV6 Inherit from COG: YD repeat protein S100761_04023 ENOG4107EV6 Inherit from COG: YD repeat protein S100761_04026 ENOG4106Z5D Glycoside Hydrolase Family 43 S100761_04028 ENOG4105C84 Histidine ammonia-lyase S100761_04029 ENOG4105CGP Urocanate hydratase S100761_04030 ENOG4105CI2 imidazolone-5-propionate hydrolase S100761_04031 ENOG4107W25 arginase agmatinase formiminoglutamase S100761_04033 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) S100761_04034 ENOG4105D9N nucleoside S100761_04036 ENOG4107RHR regulatoR S100761_04037 ENOG4108TM9 integral membrane protein S100761_04038 ENOG4105ENY Ethanolamine utilization protein eutH S100761_04039 ENOG4108PGP mmge prpd family protein S100761_04040 ENOG4105CH2 amidohydrolase S100761_04042 ENOG4108HW4 amino acid AbC transporter S100761_04043 ENOG4105EAB amino acid AbC transporter S100761_04044 ENOG4108XSB acetyltransferase, (GNAT) family S100761_04045 ENOG4105CPU Monooxygenase S100761_04046 ENOG4107QHE Choloylglycine hydrolase S100761_04047 ENOG410667J hydrolase S100761_04053 ENOG4108V5C ABC transporter S100761_04059 ENOG4105D2N Aldolase S100761_04060 ENOG4107TRN Xylose isomerase domain protein TIM barrel S100761_04061 ENOG4105F0H myo-inositol catabolism protein S100761_04062 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) S100761_04064 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) S100761_04065 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) S100761_04066 ENOG4105D7K pfkb domain protein S100761_04068 ENOG4105C26 Dehydrogenase S100761_04070 ENOG4105CPC Aldo Keto reductase S100761_04073 ENOG4107QNK )-transporter S100761_04074 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) S100761_04076 ENOG41061TZ Short-chain dehydrogenase reductase Sdr S100761_04077 ENOG4105ST3 Transcriptional regulator S100761_04078 ENOG4105C26 Dehydrogenase S100761_04079 ENOG41085PJ rdd domain containing protein S100761_04081 ENOG41085PJ rdd domain containing protein S100761_04084 ENOG4105J7D transcriptional regulator S100761_04085 ENOG4107JEE Short-chain dehydrogenase reductase Sdr S100761_04086 ENOG41061AU MarR family Transcriptional regulator S100761_04088 ENOG41067MG lrgb family S100761_04090 ENOG4105BZW Glycerate kinase S100761_04091 ENOG4105G3Z GntR family transcriptional regulator S100761_04092 ENOG4105CMG Carbohydrate kinase S100761_04093 ENOG4105C6Z Gluconate S100761_04094 ENOG4105C6Z Gluconate S100761_04095 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) S100761_04096 ENOG4105D3R alkyl hydroperoxide reductase S100761_04097 ENOG4108JU3 Alkyl hydroperoxide reductase S100761_04098 ENOG4105CS2 ec 3.2.1.21 S100761_04099 ENOG4105C5Y PTS System S100761_04100 ENOG4108S3Y transcriptional regulator S100761_04101 ENOG4107QKA exodeoxyribonuclease V beta S100761_04102 ENOG4105D0M Protease HtpX homolog S100761_04106 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 S100761_04108 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) S100761_04111 ENOG4105E2A Dehydrogenase S100761_04115 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) S100761_04116 ENOG4105WQG acetyltransferase S100761_04117 ENOG410780I phosphoprotein phosphatase activity S100761_04118 ENOG410780I phosphoprotein phosphatase activity S100761_04120 ENOG41066UZ arginase EC 3.5.3.1 S100761_04121 ENOG4108IQI permease S100761_04122 ENOG4105C8Y Acetylornithine aminotransferase S100761_04127 ENOG41082BM Transcriptional regulator, arsr family S100761_04128 ENOG4108JUB Transcriptional regulator S100761_04129 ENOG4105C0H protease S100761_04130 ENOG4105Q2H domain protein S100761_04133 ENOG4105BZU Histidine kinase S100761_04134 ENOG4105CK6 Two component transcriptional regulator (Winged helix family S100761_04139 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis S100761_04140 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase S100761_04141 ENOG4105CDU Replicative dna helicase S100761_04145 ENOG4105DJ2 Major Facilitator Superfamily S100761_04146 ENOG4105EDW glycosyl transferase, family 39 S100761_04147 ENOG4105K9Q Binds to the 23S rRNA (By similarity) S100761_04148 ENOG4105BZR domain protein S100761_04149 ENOG4108XMW Membrane S100761_04152 ENOG4105KVH Transcriptional regulator S100761_04153 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase S100761_04157 ENOG41090E6 transcriptional regulator MERR family S100761_04159 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein S100761_04160 ENOG4105DDN Pentapeptide repeat-containing protein S100761_04161 ENOG4105D94 Major Facilitator Superfamily S100761_04162 ENOG4107RSM transcriptional regulator S100761_04163 ENOG41082BV acetyltransferase S100761_04164 ENOG41081I9 integral membrane protein S100761_04166 ENOG4108U05 Transcriptional regulator S100761_04167 ENOG41082BV acetyltransferase S100761_04169 ENOG4108U7W acetyltransferase S100761_04170 ENOG4105UNS Pfam:DUF419 S100761_04171 ENOG4105NAE bifunctional deaminase-reductase domain protein S100761_04172 ENOG4105C7Z Conserved Protein S100761_04173 ENOG4107FCW Abortive infection protein S100761_04175 ENOG4108UW5 maltose o-acetyltransferase S100761_04176 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase S100761_04178 ENOG4105CGK Exodeoxyribonuclease III S100761_04179 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) S100761_04180 ENOG4108UUM single-stranded DNA-binding protein S100761_04181 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) S100761_04182 ENOG4105C3G gtp-binding protein S100761_04183 ENOG4108J2R molybdopterin oxidoreductase S100761_04184 ENOG4105VDK protein, conserved in bacteria S100761_04186 ENOG4108ZDA Sporulation protein YyaC S100761_04187 ENOG4105FA0 parb-like partition protein S100761_04188 ENOG4107QJE Chromosome Partitioning Protein S100761_04191 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) S100761_04192 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) S100761_04193 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) S100761_04196 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)