locus-tag	class	description
S101441_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
S101441_00002	COG0592	DNA-directed DNA polymerase activity
S101441_00003	COG2501	S4 domain
S101441_00004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
S101441_00006	COG0187	DNA topoisomerase II activity
S101441_00007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101441_00014	COG0517	IMP dehydrogenase activity
S101441_00014	COG0516	GMP reductase activity
S101441_00015	COG1686	Belongs to the peptidase S11 family
S101441_00016	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
S101441_00017	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
S101441_00018	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
S101441_00020	COG1428	Deoxynucleoside kinase
S101441_00021	COG1428	Deoxynucleoside kinase
S101441_00022	COG3858	chitin binding
S101441_00022	COG1388	LysM domain
S101441_00023	COG1335	isochorismatase
S101441_00024	COG0590	tRNA wobble adenosine to inosine editing
S101441_00025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
S101441_00026	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
S101441_00027	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
S101441_00036	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
S101441_00037	COG3853	Toxic anion resistance protein (TelA)
S101441_00038	COG1982	Orn Lys Arg decarboxylase major
S101441_00039	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
S101441_00040	COG3870	Protein conserved in bacteria
S101441_00041	COG1728	Protein conserved in bacteria
S101441_00042	COG0470	DNA polymerase III
S101441_00043	COG1774	PSP1 C-terminal conserved region
S101441_00044	COG4467	Involved in initiation control of chromosome replication
S101441_00045	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
S101441_00046	COG2827	Endonuclease containing a URI domain
S101441_00047	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
S101441_00048	COG2002	toxin-antitoxin pair type II binding
S101441_00049	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101441_00049	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101441_00050	COG0084	hydrolase, TatD family'
S101441_00051	COG3584	3D domain protein
S101441_00051	COG3583	domain protein
S101441_00052	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101441_00053	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
S101441_00057	COG4466	Protein conserved in bacteria
S101441_00059	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
S101441_00060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101441_00061	COG0251	oxidation-reduction process
S101441_00062	COG2088	sporulation resulting in formation of a cellular spore
S101441_00063	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
S101441_00064	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
S101441_00065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
S101441_00066	COG0193	aminoacyl-tRNA hydrolase activity
S101441_00068	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
S101441_00069	COG2002	toxin-antitoxin pair type II binding
S101441_00070	COG2244	polysaccharide biosynthetic process
S101441_00071	COG3956	TIGRFAM MazG family protein
S101441_00072	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
S101441_00075	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
S101441_00076	COG1098	S1 RNA binding domain
S101441_00079	COG2208	phosphoserine phosphatase activity
S101441_00080	COG2304	oxidoreductase activity
S101441_00081	COG0515	serine threonine protein kinase
S101441_00082	COG0037	tRNA processing
S101441_00084	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S101441_00085	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
S101441_00086	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
S101441_00087	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101441_00088	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101441_00091	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101441_00092	COG0512	Glutamine amidotransferase of anthranilate synthase
S101441_00093	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101441_00094	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
S101441_00095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
S101441_00096	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
S101441_00097	COG1396	sequence-specific DNA binding
S101441_00098	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101441_00099	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
S101441_00115	COG4463	regulation of RNA biosynthetic process
S101441_00116	COG3880	PFAM UvrB UvrC protein
S101441_00117	COG3869	Catalyzes the specific phosphorylation of arginine residues in
S101441_00118	COG0542	response to heat
S101441_00119	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
S101441_00120	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
S101441_00121	COG4956	integral membrane protein (PIN domain superfamily)
S101441_00122	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
S101441_00123	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
S101441_00124	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
S101441_00125	COG1045	serine acetyltransferase
S101441_00126	COG0215	cysteine-tRNA ligase activity
S101441_00127	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
S101441_00128	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101441_00129	COG3688	RNA-binding protein containing a PIN domain
S101441_00130	COG1595	DNA-templated transcription, initiation
S101441_00131	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101441_00132	COG0250	Participates in transcription elongation, termination and antitermination
S101441_00133	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
S101441_00134	COG0081	regulation of translation
S101441_00135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
S101441_00136	COG0222	ribosome binding
S101441_00137	COG2813	Specifically methylates the guanine in position
S101441_00138	COG0085	RNA polymerase activity
S101441_00139	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
S101441_00140	COG1358	cellular component organization or biogenesis
S101441_00141	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
S101441_00142	COG0049	tRNA binding
S101441_00143	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
S101441_00144	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
S101441_00145	COG0596	Alpha beta hydrolase
S101441_00146	COG0051	transcription antitermination factor activity, RNA binding
S101441_00147	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
S101441_00148	COG0088	Forms part of the polypeptide exit tunnel
S101441_00149	COG0089	rRNA binding
S101441_00150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
S101441_00151	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
S101441_00152	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
S101441_00153	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
S101441_00154	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
S101441_00155	COG0255	Belongs to the universal ribosomal protein uL29 family
S101441_00156	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
S101441_00157	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
S101441_00159	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
S101441_00161	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
S101441_00162	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
S101441_00163	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
S101441_00165	COG1841	ribosomal large subunit assembly
S101441_00166	COG0200	Binds to the 23S rRNA
S101441_00167	COG0201	protein transport
S101441_00168	COG0563	adenylate kinase activity
S101441_00169	COG0024	Methionine aminopeptidase
S101441_00170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
S101441_00171	COG0257	Belongs to the bacterial ribosomal protein bL36 family
S101441_00172	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
S101441_00173	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
S101441_00174	COG0202	RNA polymerase activity
S101441_00175	COG0203	ribosomal protein L17
S101441_00176	COG1122	ATPase activity
S101441_00177	COG1122	ATPase activity
S101441_00178	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101441_00179	COG0101	tRNA pseudouridine synthase activity
S101441_00180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
S101441_00181	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
S101441_00182	COG2226	methyltransferase
S101441_00184	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101441_00185	COG0489	protein tyrosine kinase activity
S101441_00187	COG2194	sulfuric ester hydrolase activity
S101441_00188	COG0726	polysaccharide deacetylase
S101441_00204	COG0659	secondary active sulfate transmembrane transporter activity
S101441_00206	COG0385	Bile acid
S101441_00207	COG2819	hydrolase of the alpha beta superfamily
S101441_00208	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_00209	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_00210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101441_00211	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101441_00211	COG2207	Transcriptional regulator
S101441_00212	COG3876	Protein conserved in bacteria
S101441_00213	COG3876	Protein conserved in bacteria
S101441_00214	COG1472	Belongs to the glycosyl hydrolase 3 family
S101441_00215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101441_00216	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_00216	COG1263	PTS System
S101441_00217	COG1737	Transcriptional regulator
S101441_00218	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
S101441_00219	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_00220	COG1683	Conserved Protein
S101441_00226	COG1595	DNA-templated transcription, initiation
S101441_00227	COG5662	AntiSigma factor
S101441_00228	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101441_00229	COG4856	YbbR-like protein
S101441_00230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S101441_00231	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
S101441_00234	COG0318	PFAM AMP-dependent synthetase and ligase
S101441_00234	COG0300	oxidoreductase activity
S101441_00234	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_00234	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_00234	COG3321	synthase
S101441_00238	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S101441_00239	COG3002	Belongs to the UPF0753 family
S101441_00240	COG0288	reversible hydration of carbon dioxide
S101441_00242	COG5609	conserved protein (DUF2294)
S101441_00243	COG0745	RESPONSE REGULATOR receiver
S101441_00244	COG0642	Histidine kinase
S101441_00245	COG0642	Histidine kinase
S101441_00247	COG0515	serine threonine protein kinase
S101441_00250	COG1113	amino acid transport
S101441_00255	COG2602	Beta-lactamase
S101441_00256	COG2124	cytochrome p450
S101441_00258	COG0531	amino acid
S101441_00259	COG0584	glycerophosphoryl diester phosphodiesterase
S101441_00260	COG2271	Major facilitator Superfamily
S101441_00262	COG0456	acetyltransferase
S101441_00262	COG1846	Transcriptional regulator
S101441_00263	COG2271	Major facilitator Superfamily
S101441_00264	COG2271	Major facilitator Superfamily
S101441_00267	COG3409	Peptidoglycan-binding domain 1 protein
S101441_00268	COG0697	spore germination
S101441_00269	COG2207	Transcriptional regulator
S101441_00269	COG1917	Cupin 2, conserved barrel domain protein
S101441_00274	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
S101441_00275	COG3591	Belongs to the peptidase S1B family
S101441_00277	COG0596	Alpha beta hydrolase
S101441_00278	COG1183	phosphatidylcholine synthase activity
S101441_00279	COG0586	Pfam SNARE associated Golgi protein
S101441_00280	COG0688	phosphatidylethanolamine metabolic process
S101441_00282	COG2312	Erythromycin esterase
S101441_00283	COG2207	Transcriptional regulator
S101441_00285	COG1301	dicarboxylic acid transport
S101441_00286	COG1263	PTS System
S101441_00286	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_00286	COG2190	(PTS) system
S101441_00287	COG0363	glucosamine-6-phosphate deaminase activity
S101441_00290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101441_00291	COG0833	amino acid
S101441_00292	COG2040	homocysteine
S101441_00293	COG1115	amino acid carrier protein
S101441_00294	COG1115	amino acid carrier protein
S101441_00295	COG2066	Belongs to the glutaminase family
S101441_00296	COG4191	Histidine kinase
S101441_00297	COG0784	Response regulator, receiver
S101441_00298	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
S101441_00299	COG1012	belongs to the aldehyde dehydrogenase family
S101441_00300	COG2271	Major facilitator Superfamily
S101441_00301	COG4948	Mandelate Racemase Muconate Lactonizing
S101441_00302	COG2186	Transcriptional regulator
S101441_00303	COG2721	sulfolactate sulfo-lyase activity
S101441_00304	COG3173	Aminoglycoside phosphotransferase
S101441_00306	COG0697	spore germination
S101441_00307	COG0745	RESPONSE REGULATOR receiver
S101441_00308	COG2205	protein histidine kinase activity
S101441_00309	COG1131	(ABC) transporter
S101441_00312	COG3773	Cell wall hydrolase
S101441_00314	COG2304	oxidoreductase activity
S101441_00315	COG3540	Alkaline phosphatase
S101441_00316	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101441_00317	COG0805	protein transport
S101441_00318	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
S101441_00319	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101441_00320	COG0477	Major facilitator Superfamily
S101441_00321	COG1309	transcriptional regulator
S101441_00322	COG0252	asparaginase activity
S101441_00323	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S101441_00324	COG1714	RDD family
S101441_00325	COG3012	SEC-C Motif Domain Protein
S101441_00325	COG1405	negative regulation of cell septum assembly
S101441_00326	COG3290	protein histidine kinase activity
S101441_00327	COG3279	Response regulator of the LytR AlgR family
S101441_00328	COG4555	ABC transporter
S101441_00329	COG1668	transmembrane transport
S101441_00330	COG0667	Aldo Keto reductase
S101441_00331	COG0667	Aldo Keto reductase
S101441_00333	COG1595	DNA-templated transcription, initiation
S101441_00334	COG1595	DNA-templated transcription, initiation
S101441_00335	COG1876	peptidase activity
S101441_00336	COG0457	Tetratricopeptide repeat
S101441_00337	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_00338	COG0366	Alpha amylase catalytic
S101441_00339	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101441_00340	COG1121	(ABC) transporter
S101441_00341	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101441_00344	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101441_00345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101441_00346	COG2310	stress, protein
S101441_00347	COG2310	stress, protein
S101441_00348	COG2310	stress, protein
S101441_00349	COG0861	Integral membrane protein TerC family
S101441_00351	COG3853	Toxic anion resistance protein (TelA)
S101441_00352	COG0477	Major facilitator Superfamily
S101441_00353	COG2814	Major facilitator Superfamily
S101441_00354	COG1104	cysteine desulfurase activity
S101441_00362	COG0640	Transcriptional regulator
S101441_00363	COG0517	IMP dehydrogenase activity
S101441_00363	COG4175	Glycine betaine
S101441_00364	COG4176	ABC-type proline glycine betaine transport system permease component
S101441_00365	COG2113	Glycine betaine
S101441_00366	COG1473	amidohydrolase
S101441_00367	COG1288	antiporter activity
S101441_00369	COG0366	Alpha amylase catalytic
S101441_00370	COG0366	Alpha amylase catalytic
S101441_00371	COG0039	L-malate dehydrogenase activity
S101441_00372	COG1620	l-lactate permease
S101441_00373	COG3403	YqcI/YcgG family
S101441_00374	COG1113	amino acid transport
S101441_00375	COG1113	amino acid transport
S101441_00376	COG3665	Urea carboxylase-associated protein
S101441_00377	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
S101441_00378	COG1660	Displays ATPase and GTPase activities
S101441_00379	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
S101441_00380	COG2226	methyltransferase
S101441_00381	COG0583	DNA-binding transcription factor activity
S101441_00382	COG3458	cephalosporin-C deacetylase activity
S101441_00383	COG3541	Predicted nucleotidyltransferase
S101441_00384	COG0506	proline dehydrogenase activity
S101441_00385	COG1012	belongs to the aldehyde dehydrogenase family
S101441_00386	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101441_00387	COG2508	Transcriptional regulator
S101441_00388	COG3689	TIGRFAM TIGR03943 family protein
S101441_00389	COG0701	Predicted permease
S101441_00390	COG2267	carboxylic ester hydrolase activity
S101441_00391	COG0492	ferredoxin-NADP+ reductase activity
S101441_00392	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101441_00392	COG1587	Uroporphyrinogen-III synthase
S101441_00393	COG2146	nitrite reductase [NAD(P)H] activity
S101441_00394	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101441_00395	COG0243	molybdopterin cofactor binding
S101441_00396	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101441_00397	COG2223	nitrite transmembrane transporter activity
S101441_00398	COG1469	GTP cyclohydrolase I activity
S101441_00399	COG1376	ErfK ybiS ycfS ynhG family protein
S101441_00400	COG0523	cobalamin synthesis protein
S101441_00401	COG0523	cobalamin synthesis protein
S101441_00402	COG0765	amino acid transport
S101441_00403	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101441_00406	COG1714	RDD family
S101441_00408	COG1846	Transcriptional regulator
S101441_00412	COG2723	6-phospho-beta-galactosidase activity
S101441_00414	COG3209	COG3209 Rhs family protein
S101441_00415	COG0840	transmembrane signaling receptor activity
S101441_00415	COG3290	protein histidine kinase activity
S101441_00416	COG0840	transmembrane signaling receptor activity
S101441_00416	COG3290	protein histidine kinase activity
S101441_00417	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
S101441_00418	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
S101441_00419	COG1733	regulation of RNA biosynthetic process
S101441_00420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_00421	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_00422	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_00423	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
S101441_00424	COG2814	Major facilitator Superfamily
S101441_00426	COG0697	spore germination
S101441_00427	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101441_00429	COG2364	Membrane
S101441_00430	COG1126	abc transporter atp-binding protein
S101441_00431	COG0765	amino acid transport
S101441_00432	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101441_00433	COG0583	DNA-binding transcription factor activity
S101441_00434	COG0163	prenyltransferase activity
S101441_00435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S101441_00438	COG0596	Alpha beta hydrolase
S101441_00439	COG3104	oligopeptide transport
S101441_00440	COG5434	Belongs to the glycosyl hydrolase 28 family
S101441_00443	COG0697	spore germination
S101441_00445	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101441_00446	COG1136	(ABC) transporter
S101441_00447	COG0577	efflux transmembrane transporter activity
S101441_00448	COG0745	RESPONSE REGULATOR receiver
S101441_00449	COG3850	Histidine kinase
S101441_00449	COG5002	protein histidine kinase activity
S101441_00450	COG0457	Tetratricopeptide repeat
S101441_00453	COG0527	aspartate kinase activity
S101441_00455	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_00456	COG4605	iron ion homeostasis
S101441_00457	COG4604	ABC transporter, ATP-binding protein
S101441_00458	COG4607	ABC-type enterochelin transport system periplasmic component
S101441_00459	COG2814	Major facilitator Superfamily
S101441_00460	COG1309	transcriptional regulator
S101441_00461	COG0778	Nitroreductase
S101441_00462	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101441_00463	COG0640	Transcriptional regulator
S101441_00464	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101441_00465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S101441_00466	COG1012	belongs to the aldehyde dehydrogenase family
S101441_00467	COG4975	Glucose uptake
S101441_00468	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_00469	COG4549	nuclear export factor GLE1
S101441_00470	COG1276	copper resistance
S101441_00470	COG2372	response to copper ion
S101441_00471	COG1349	DNA-binding transcription factor activity
S101441_00473	COG2213	PTS system mannitol-specific
S101441_00474	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_00475	COG0246	Mannitol dehydrogenase
S101441_00476	COG0473	3-isopropylmalate dehydrogenase activity
S101441_00478	COG0681	Belongs to the peptidase S26 family
S101441_00479	COG0412	Dienelactone hydrolase
S101441_00480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S101441_00481	COG2801	Transposase and inactivated derivatives
S101441_00483	COG0561	phosphatase activity
S101441_00484	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
S101441_00485	COG1914	H( )-stimulated, divalent metal cation uptake system
S101441_00486	COG4336	lyase activity
S101441_00487	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
S101441_00488	COG1984	allophanate hydrolase subunit 2
S101441_00489	COG1414	Transcriptional regulator
S101441_00490	COG2755	lipolytic protein G-D-S-L family
S101441_00492	COG2329	Antibiotic biosynthesis monooxygenase
S101441_00493	COG0768	penicillin binding
S101441_00494	COG4989	oxidoreductase activity
S101441_00495	COG3711	transcriptional antiterminator
S101441_00496	COG0318	PFAM AMP-dependent synthetase and ligase
S101441_00497	COG2226	methyltransferase
S101441_00498	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_00499	COG1917	Cupin 2, conserved barrel domain protein
S101441_00500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_00501	COG3871	stress protein (general stress protein 26)
S101441_00503	COG2814	Major facilitator Superfamily
S101441_00504	COG1522	sequence-specific DNA binding
S101441_00505	COG0551	DNA topoisomerase type I activity
S101441_00505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101441_00506	COG0494	nUDIX hydrolase
S101441_00507	COG0028	Belongs to the TPP enzyme family
S101441_00512	COG1914	H( )-stimulated, divalent metal cation uptake system
S101441_00513	COG2261	transglycosylase associated protein
S101441_00514	COG4876	unkown
S101441_00515	COG2217	Heavy metal translocating P-type atpase
S101441_00516	COG3729	General stress protein
S101441_00517	COG0662	Cupin 2, conserved barrel domain protein
S101441_00518	COG2329	Antibiotic biosynthesis monooxygenase
S101441_00519	COG3546	catalase activity
S101441_00520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
S101441_00521	COG3290	protein histidine kinase activity
S101441_00522	COG4565	transcriptional regulatory protein
S101441_00523	COG1301	dicarboxylic acid transport
S101441_00526	COG0628	permease
S101441_00527	COG1131	(ABC) transporter
S101441_00528	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101441_00530	COG1960	acyl-CoA dehydrogenase activity
S101441_00533	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101441_00534	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_00535	COG1181	Belongs to the D-alanine--D-alanine ligase family
S101441_00536	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
S101441_00537	COG0513	Belongs to the DEAD box helicase family
S101441_00538	COG3402	PFAM membrane-flanked domain
S101441_00539	COG3428	Bacterial PH domain
S101441_00540	COG0705	Rhomboid family
S101441_00541	COG0736	holo-[acyl-carrier-protein] synthase activity
S101441_00542	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
S101441_00543	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101441_00544	COG0864	Transcriptional regulator
S101441_00545	COG2337	Toxic component of a toxin-antitoxin (TA) module
S101441_00546	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_00547	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_00548	COG2172	sigma factor antagonist activity
S101441_00549	COG2208	phosphoserine phosphatase activity
S101441_00550	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_00551	COG2172	sigma factor antagonist activity
S101441_00552	COG1191	sigma factor activity
S101441_00553	COG2208	phosphoserine phosphatase activity
S101441_00554	COG2183	response to ionizing radiation
S101441_00555	COG3091	SprT-like family
S101441_00564	COG0583	DNA-binding transcription factor activity
S101441_00565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_00567	COG5444	nuclease activity
S101441_00568	COG1476	TRANSCRIPTIONal
S101441_00573	COG0693	protein deglycase activity
S101441_00574	COG1278	Cold shock
S101441_00575	COG1329	Transcriptional regulator
S101441_00578	COG0697	spore germination
S101441_00579	COG1917	Cupin 2, conserved barrel domain protein
S101441_00579	COG2207	Transcriptional regulator
S101441_00580	COG0697	spore germination
S101441_00581	COG3708	Transcriptional regulator
S101441_00581	COG2207	Transcriptional regulator
S101441_00582	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101441_00583	COG0477	Major facilitator Superfamily
S101441_00584	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
S101441_00587	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_00588	COG1309	transcriptional regulator
S101441_00589	COG0697	spore germination
S101441_00590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101441_00591	COG2030	dehydratase
S101441_00592	COG3545	Serine hydrolase
S101441_00593	COG1733	regulation of RNA biosynthetic process
S101441_00594	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101441_00595	COG0640	Transcriptional regulator
S101441_00596	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101441_00597	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101441_00598	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_00599	COG0697	spore germination
S101441_00600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101441_00601	COG0076	glutamate decarboxylase activity
S101441_00602	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S101441_00603	COG0640	Transcriptional regulator
S101441_00604	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S101441_00606	COG4585	Histidine kinase
S101441_00607	COG2197	response regulator
S101441_00608	COG2409	Drug exporters of the RND superfamily
S101441_00612	COG0596	Alpha beta hydrolase
S101441_00613	COG1811	Na channel or pump
S101441_00614	COG0789	Transcriptional regulator
S101441_00614	COG4978	Transcriptional regulator
S101441_00615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101441_00616	COG0778	Nitroreductase
S101441_00617	COG0346	lactoylglutathione lyase activity
S101441_00618	COG2259	Doxx family
S101441_00619	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_00623	COG2323	membrane
S101441_00624	COG2323	membrane
S101441_00625	COG0071	Belongs to the small heat shock protein (HSP20) family
S101441_00628	COG1309	transcriptional regulator
S101441_00630	COG0456	acetyltransferase
S101441_00632	COG1113	amino acid transport
S101441_00633	COG2318	DinB family
S101441_00634	COG1846	Transcriptional regulator
S101441_00635	COG2409	Drug exporters of the RND superfamily
S101441_00635	COG1033	growth of symbiont in host cell
S101441_00636	COG0778	Nitroreductase
S101441_00637	COG1846	Transcriptional regulator
S101441_00638	COG2814	Major facilitator Superfamily
S101441_00639	COG0730	response to heat
S101441_00640	COG1802	Transcriptional regulator
S101441_00641	COG1388	LysM domain
S101441_00641	COG3858	chitin binding
S101441_00642	COG1819	glycosyl
S101441_00644	COG1785	Belongs to the alkaline phosphatase family
S101441_00645	COG5646	InterPro IPR014922
S101441_00647	COG0454	-acetyltransferase
S101441_00648	COG1078	dGTPase activity
S101441_00649	COG1388	LysM domain
S101441_00650	COG2814	Major facilitator Superfamily
S101441_00651	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101441_00652	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101441_00653	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101441_00654	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101441_00655	COG2723	6-phospho-beta-galactosidase activity
S101441_00656	COG2188	Transcriptional regulator
S101441_00657	COG1940	carbohydrate kinase activity
S101441_00658	COG1482	cell wall glycoprotein biosynthetic process
S101441_00659	COG1482	cell wall glycoprotein biosynthetic process
S101441_00660	COG4124	Belongs to the glycosyl hydrolase 26 family
S101441_00669	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
S101441_00670	COG0802	atpase or kinase
S101441_00671	COG1214	PFAM Peptidase M22, glycoprotease
S101441_00672	COG0456	acetyltransferase
S101441_00673	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
S101441_00674	COG0488	(ABC) transporter
S101441_00675	COG0315	cyclic pyranopterin monophosphate synthase activity
S101441_00676	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
S101441_00677	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101441_00678	COG0805	protein transport
S101441_00680	COG1266	CAAX protease self-immunity
S101441_00681	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
S101441_00682	COG0459	protein refolding
S101441_00683	COG4974	Belongs to the 'phage' integrase family
S101441_00684	COG2856	Zn peptidase
S101441_00685	COG1396	sequence-specific DNA binding
S101441_00697	COG3935	DnaD domain protein
S101441_00698	COG1484	DNA-dependent DNA replication
S101441_00700	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
S101441_00707	COG3677	Transposase
S101441_00725	COG5280	Phage tail tape measure protein TP901
S101441_00725	COG3953	SLT domain
S101441_00727	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101441_00734	COG1388	LysM domain
S101441_00734	COG3409	Peptidoglycan-binding domain 1 protein
S101441_00734	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101441_00736	COG5444	nuclease activity
S101441_00748	COG0457	Tetratricopeptide repeat
S101441_00749	COG1063	alcohol dehydrogenase
S101441_00750	COG2211	Major facilitator Superfamily
S101441_00751	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101441_00752	COG1842	Phage shock protein A
S101441_00753	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101441_00754	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
S101441_00755	COG4260	virion core protein, lumpy skin disease virus
S101441_00758	COG2814	Major facilitator Superfamily
S101441_00759	COG1063	alcohol dehydrogenase
S101441_00760	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
S101441_00761	COG0823	Involved in the tonB-independent uptake of proteins
S101441_00763	COG2801	Transposase and inactivated derivatives
S101441_00766	COG2267	carboxylic ester hydrolase activity
S101441_00768	COG2132	Multicopper oxidase
S101441_00769	COG1113	amino acid transport
S101441_00770	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101441_00771	COG0714	Associated with various cellular activities
S101441_00772	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
S101441_00773	COG1305	Transglutaminase-like
S101441_00774	COG0519	Catalyzes the synthesis of GMP from XMP
S101441_00774	COG0518	GMP synthase (glutamine-hydrolyzing) activity
S101441_00777	COG2252	PERMEase
S101441_00778	COG3064	Membrane
S101441_00782	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
S101441_00784	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
S101441_00785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
S101441_00786	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
S101441_00787	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
S101441_00788	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S101441_00789	COG0047	phosphoribosylformylglycinamidine synthase activity
S101441_00790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S101441_00791	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
S101441_00792	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
S101441_00793	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
S101441_00794	COG0138	bifunctional purine biosynthesis protein purh
S101441_00795	COG0151	Belongs to the GarS family
S101441_00796	COG1522	sequence-specific DNA binding
S101441_00797	COG0531	amino acid
S101441_00799	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S101441_00800	COG1470	cell adhesion involved in biofilm formation
S101441_00801	COG4496	protein, YerC YecD
S101441_00802	COG0069	glutamate synthase activity
S101441_00804	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
S101441_00805	COG0210	DNA helicase
S101441_00806	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
S101441_00807	COG4851	CamS sex pheromone cAM373 precursor
S101441_00808	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101441_00809	COG1285	pathogenesis
S101441_00810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101441_00811	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
S101441_00812	COG0154	amidase activity
S101441_00813	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
S101441_00814	COG1309	transcriptional regulator
S101441_00815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S101441_00816	COG1597	lipid kinase activity
S101441_00817	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101441_00822	COG0457	Tetratricopeptide repeat
S101441_00826	COG5444	nuclease activity
S101441_00828	COG3586	endonuclease activity
S101441_00830	COG0457	Tetratricopeptide repeat
S101441_00832	COG0217	transcriptional regulatory protein
S101441_00834	COG1309	transcriptional regulator
S101441_00835	COG3631	Ketosteroid isomerase-related protein
S101441_00836	COG0702	epimerase
S101441_00839	COG3546	catalase activity
S101441_00840	COG0454	-acetyltransferase
S101441_00841	COG5578	integral membrane protein
S101441_00842	COG2972	Histidine kinase
S101441_00843	COG2207	Transcriptional regulator
S101441_00843	COG4753	response regulator
S101441_00844	COG4753	response regulator
S101441_00844	COG2207	Transcriptional regulator
S101441_00845	COG1653	transport
S101441_00846	COG1175	transmembrane transport
S101441_00847	COG1175	transmembrane transport
S101441_00848	COG0395	ABC-type sugar transport system, permease component
S101441_00849	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
S101441_00850	COG2207	Transcriptional regulator
S101441_00851	COG2755	lipolytic protein G-D-S-L family
S101441_00853	COG5578	integral membrane protein
S101441_00854	COG3401	FG-GAP repeat protein
S101441_00855	COG3401	FG-GAP repeat protein
S101441_00856	COG2755	lipolytic protein G-D-S-L family
S101441_00857	COG1874	Beta-galactosidase
S101441_00860	COG1653	transport
S101441_00861	COG4209	transmembrane transport
S101441_00862	COG0395	ABC-type sugar transport system, permease component
S101441_00863	COG1486	melibiose metabolic process
S101441_00864	COG2323	membrane
S101441_00865	COG2329	Antibiotic biosynthesis monooxygenase
S101441_00866	COG0346	lactoylglutathione lyase activity
S101441_00869	COG5583	Uncharacterized small protein (DUF2292)
S101441_00870	COG0670	Belongs to the BI1 family
S101441_00871	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101441_00872	COG1715	Restriction endonuclease
S101441_00874	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101441_00874	COG2124	cytochrome p450
S101441_00875	COG1368	sulfuric ester hydrolase activity
S101441_00876	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
S101441_00877	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101441_00878	COG1442	glycosyl transferase family 8
S101441_00879	COG1216	Glycosyl transferase, family 2
S101441_00880	COG1442	glycosyl transferase family 8
S101441_00881	COG2223	nitrite transmembrane transporter activity
S101441_00882	COG1011	Hydrolase
S101441_00883	COG0531	amino acid
S101441_00884	COG1012	belongs to the aldehyde dehydrogenase family
S101441_00885	COG0840	transmembrane signaling receptor activity
S101441_00886	COG0488	(ABC) transporter
S101441_00888	COG0789	Transcriptional regulator
S101441_00889	COG2814	Major facilitator Superfamily
S101441_00892	COG2801	Transposase and inactivated derivatives
S101441_00893	COG0488	(ABC) transporter
S101441_00894	COG0513	Belongs to the DEAD box helicase family
S101441_00895	COG0456	acetyltransferase
S101441_00896	COG3328	transposase activity
S101441_00897	COG2130	NADP-dependent
S101441_00898	COG1120	ATPase activity
S101441_00899	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_00900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_00901	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
S101441_00904	COG3866	Pectate lyase
S101441_00905	COG0471	metal ion transport
S101441_00906	COG3290	protein histidine kinase activity
S101441_00907	COG4565	transcriptional regulatory protein
S101441_00908	COG3181	Tripartite tricarboxylate transporter family receptor
S101441_00910	COG2851	Citrate transporter
S101441_00911	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101441_00912	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
S101441_00913	COG1254	Belongs to the acylphosphatase family
S101441_00914	COG2258	MOSC domain
S101441_00918	COG0024	Methionine aminopeptidase
S101441_00919	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_00919	COG1263	PTS System
S101441_00920	COG1368	sulfuric ester hydrolase activity
S101441_00922	COG0697	spore germination
S101441_00923	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_00923	COG1263	PTS System
S101441_00924	COG0366	Alpha amylase catalytic
S101441_00925	COG2188	Transcriptional regulator
S101441_00926	COG0778	Nitroreductase
S101441_00927	COG0737	Belongs to the 5'-nucleotidase family
S101441_00928	COG0693	protein deglycase activity
S101441_00929	COG2814	Major facilitator Superfamily
S101441_00930	COG4840	Belongs to the UPF0435 family
S101441_00931	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101441_00932	COG4980	gas vesicle protein
S101441_00933	COG1295	ribonuclease BN
S101441_00934	COG0477	Major facilitator Superfamily
S101441_00935	COG0387	Pfam Sodium calcium exchanger
S101441_00937	COG0668	transmembrane transport
S101441_00938	COG0535	radical SAM domain protein
S101441_00940	COG0726	polysaccharide deacetylase
S101441_00941	COG2084	Dehydrogenase
S101441_00942	COG0598	Magnesium transport protein CorA
S101441_00943	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
S101441_00944	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101441_00946	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101441_00947	COG4637	Psort location Cytoplasmic, score
S101441_00949	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101441_00950	COG0022	dehydrogenase e1 component
S101441_00951	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101441_00952	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101441_00953	COG3284	Transcriptional regulator
S101441_00955	COG1742	UPF0060 membrane protein
S101441_00960	COG4842	Belongs to the WXG100 family
S101441_00961	COG1486	melibiose metabolic process
S101441_00962	COG1737	Transcriptional regulator
S101441_00963	COG1263	PTS System
S101441_00963	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_00964	COG1132	(ABC) transporter
S101441_00965	COG1132	(ABC) transporter
S101441_00966	COG2259	Doxx family
S101441_00967	COG2514	catechol 2,3-dioxygenase activity
S101441_00968	COG4585	Histidine kinase
S101441_00969	COG2197	response regulator
S101441_00970	COG1131	(ABC) transporter
S101441_00971	COG0842	Transport permease protein
S101441_00971	COG1511	domain protein
S101441_00972	COG0842	Transport permease protein
S101441_00973	COG1695	Transcriptional regulator
S101441_00974	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S101441_00975	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
S101441_00976	COG1309	transcriptional regulator
S101441_00977	COG2814	Major facilitator Superfamily
S101441_00978	COG2318	DinB family
S101441_00979	COG2814	Major facilitator Superfamily
S101441_00980	COG2814	Major facilitator Superfamily
S101441_00981	COG1846	Transcriptional regulator
S101441_00982	COG0392	lysyltransferase activity
S101441_00982	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
S101441_00983	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101441_00984	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_00985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_00986	COG0384	phenazine biosynthesis protein PhzF
S101441_00987	COG0778	Nitroreductase
S101441_00990	COG1090	epimerase
S101441_00991	COG2137	regulation of response to DNA damage stimulus
S101441_00994	COG2814	Major facilitator Superfamily
S101441_00997	COG3103	Sh3 type 3 domain protein
S101441_00998	COG5658	integral membrane protein
S101441_00999	COG0596	Alpha beta hydrolase
S101441_01000	COG0463	Glycosyl transferase, family 2
S101441_01001	COG4485	Bacterial membrane protein, YfhO
S101441_01002	COG1988	membrane-bound metal-dependent
S101441_01003	COG1194	a g-specific adenine glycosylase
S101441_01005	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_01008	COG3557	Belongs to the UPF0374 family
S101441_01009	COG1132	(ABC) transporter
S101441_01010	COG4129	membrane
S101441_01011	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
S101441_01012	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
S101441_01013	COG0735	belongs to the Fur family
S101441_01036	COG2801	Transposase and inactivated derivatives
S101441_01039	COG4326	sporulation control protein
S101441_01041	COG3340	Belongs to the peptidase S51 family
S101441_01042	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
S101441_01044	COG0753	catalase activity
S101441_01045	COG1116	anion transmembrane transporter activity
S101441_01046	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101441_01047	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101441_01048	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101441_01051	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
S101441_01053	COG1476	TRANSCRIPTIONal
S101441_01055	COG3382	B3 4 domain protein
S101441_01056	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
S101441_01058	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
S101441_01059	COG0789	Transcriptional regulator
S101441_01060	COG1664	Polymer-forming cytoskeletal
S101441_01061	COG1664	Polymer-forming cytoskeletal
S101441_01062	COG2766	serine protein kinase
S101441_01063	COG2718	Belongs to the UPF0229 family
S101441_01064	COG1846	Transcriptional regulator
S101441_01065	COG1566	PFAM secretion protein HlyD family protein
S101441_01066	COG2814	Major facilitator Superfamily
S101441_01067	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101441_01070	COG1725	Transcriptional regulator
S101441_01071	COG1131	(ABC) transporter
S101441_01072	COG1131	(ABC) transporter
S101441_01073	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101441_01074	COG1278	Cold shock
S101441_01075	COG1464	Belongs to the NlpA lipoprotein family
S101441_01076	COG3706	GGDEF domain
S101441_01077	COG1823	symporter activity
S101441_01078	COG5444	nuclease activity
S101441_01083	COG0582	viral genome integration into host DNA
S101441_01093	COG0433	COG0433 Predicted ATPase
S101441_01094	COG0433	COG0433 Predicted ATPase
S101441_01096	COG5644	endopeptidase inhibitor activity
S101441_01097	COG0741	lytic transglycosylase activity
S101441_01097	COG0791	NLP P60 protein
S101441_01101	COG0457	Tetratricopeptide repeat
S101441_01106	COG5577	PFAM Coat F domain
S101441_01107	COG4085	toxin activity
S101441_01107	COG0737	Belongs to the 5'-nucleotidase family
S101441_01107	COG1525	nuclease
S101441_01108	COG3764	Sortase (surface protein transpeptidase)
S101441_01109	COG0564	pseudouridine synthase activity
S101441_01111	COG0517	IMP dehydrogenase activity
S101441_01112	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101441_01113	COG3153	acetyltransferase
S101441_01113	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101441_01114	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101441_01115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
S101441_01116	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
S101441_01117	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
S101441_01118	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
S101441_01119	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S101441_01120	COG4585	Histidine kinase
S101441_01120	COG2203	Gaf domain
S101441_01121	COG2197	response regulator
S101441_01122	COG0431	NADPH-dependent FMN reductase
S101441_01125	COG1388	LysM domain
S101441_01125	COG0791	NLP P60 protein
S101441_01126	COG1959	2 iron, 2 sulfur cluster binding
S101441_01129	COG0668	transmembrane transport
S101441_01130	COG2719	SpoVR family
S101441_01131	COG1785	Belongs to the alkaline phosphatase family
S101441_01132	COG1388	LysM domain
S101441_01132	COG0791	NLP P60 protein
S101441_01133	COG0583	DNA-binding transcription factor activity
S101441_01134	COG0372	Belongs to the citrate synthase family
S101441_01135	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_01136	COG0531	amino acid
S101441_01137	COG0733	neurotransmitter:sodium symporter activity
S101441_01138	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101441_01139	COG0456	acetyltransferase
S101441_01142	COG1595	DNA-templated transcription, initiation
S101441_01143	COG0667	Aldo Keto reductase
S101441_01144	COG0204	Acyl-transferase
S101441_01145	COG1253	flavin adenine dinucleotide binding
S101441_01146	COG0789	Transcriptional regulator
S101441_01147	COG0436	Aminotransferase
S101441_01148	COG0436	Aminotransferase
S101441_01149	COG1253	flavin adenine dinucleotide binding
S101441_01150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101441_01151	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101441_01152	COG0584	glycerophosphoryl diester phosphodiesterase
S101441_01154	COG0668	transmembrane transport
S101441_01155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
S101441_01156	COG0726	polysaccharide deacetylase
S101441_01157	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101441_01158	COG1757	Na H antiporter
S101441_01159	COG0589	response to stress
S101441_01160	COG1132	(ABC) transporter
S101441_01161	COG1132	(ABC) transporter
S101441_01162	COG0702	epimerase
S101441_01165	COG0189	ligase activity
S101441_01166	COG0189	ligase activity
S101441_01167	COG4399	Belongs to the UPF0754 family
S101441_01168	COG3679	Belongs to the UPF0342 family
S101441_01169	COG4335	DNA alkylation repair
S101441_01170	COG4335	DNA alkylation repair
S101441_01171	COG0561	phosphatase activity
S101441_01172	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101441_01173	COG0475	glutathione-regulated potassium exporter activity
S101441_01174	COG0490	domain, Protein
S101441_01176	COG1024	Enoyl-CoA hydratase
S101441_01178	COG4152	abc transporter atp-binding protein
S101441_01179	COG1668	transmembrane transport
S101441_01180	COG0420	3'-5' exonuclease activity
S101441_01181	COG4717	serine-type aminopeptidase activity
S101441_01182	COG3481	metal-dependent phosphohydrolase, HD sub domain
S101441_01184	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101441_01187	COG1846	Transcriptional regulator
S101441_01188	COG4980	gas vesicle protein
S101441_01191	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
S101441_01192	COG0537	adenosine 5'-monophosphoramidase activity
S101441_01193	COG1131	(ABC) transporter
S101441_01194	COG4473	ABC transporter
S101441_01196	COG1473	amidohydrolase
S101441_01197	COG3069	C4-dicarboxylate transmembrane transporter activity
S101441_01199	COG2329	Antibiotic biosynthesis monooxygenase
S101441_01200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101441_01201	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
S101441_01204	COG1309	transcriptional regulator
S101441_01205	COG1511	domain protein
S101441_01208	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101441_01209	COG4377	Putative membrane peptidase family (DUF2324)
S101441_01211	COG1363	Peptidase, m42
S101441_01212	COG4405	Protein conserved in bacteria
S101441_01213	COG1301	dicarboxylic acid transport
S101441_01214	COG1234	tRNA 3'-trailer cleavage
S101441_01215	COG0095	Lipoate-protein ligase
S101441_01216	COG0702	epimerase
S101441_01217	COG0318	PFAM AMP-dependent synthetase and ligase
S101441_01220	COG0501	Belongs to the peptidase M48B family
S101441_01222	COG0456	acetyltransferase
S101441_01223	COG0604	alcohol dehydrogenase
S101441_01224	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
S101441_01225	COG2801	Transposase and inactivated derivatives
S101441_01227	COG0406	alpha-ribazole phosphatase activity
S101441_01228	COG0183	Belongs to the thiolase family
S101441_01229	COG0318	PFAM AMP-dependent synthetase and ligase
S101441_01230	COG1268	BioY protein
S101441_01231	COG0840	transmembrane signaling receptor activity
S101441_01232	COG0723	plastoquinol--plastocyanin reductase activity
S101441_01232	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101441_01233	COG0723	plastoquinol--plastocyanin reductase activity
S101441_01233	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101441_01234	COG0723	plastoquinol--plastocyanin reductase activity
S101441_01234	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101441_01235	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_01237	COG4903	ComK protein
S101441_01238	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_01240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101441_01243	COG0398	Pfam SNARE associated Golgi protein
S101441_01244	COG0681	Belongs to the peptidase S26 family
S101441_01245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101441_01246	COG1846	Transcriptional regulator
S101441_01249	COG0738	Major facilitator superfamily
S101441_01250	COG0673	inositol 2-dehydrogenase activity
S101441_01251	COG0561	phosphatase activity
S101441_01252	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101441_01253	COG1609	Transcriptional regulator
S101441_01254	COG3180	Ammonia monooxygenase
S101441_01255	COG0477	Major facilitator Superfamily
S101441_01255	COG2814	Major facilitator Superfamily
S101441_01256	COG4533	DNA binding
S101441_01257	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
S101441_01258	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
S101441_01259	COG1074	ATP-dependent DNA helicase activity
S101441_01260	COG0420	3'-5' exonuclease activity
S101441_01261	COG0419	ATPase involved in DNA repair
S101441_01262	COG1403	HNH endonuclease
S101441_01270	COG5337	Spore coat protein CotH
S101441_01271	COG0179	Fumarylacetoacetate (FAA) hydrolase
S101441_01273	COG1404	Belongs to the peptidase S8 family
S101441_01277	COG0367	asparagine synthase
S101441_01278	COG1562	ergosterol biosynthetic process
S101441_01279	COG0534	Mate efflux family protein
S101441_01280	COG1917	Cupin 2, conserved barrel domain protein
S101441_01280	COG2207	Transcriptional regulator
S101441_01281	COG1609	Transcriptional regulator
S101441_01282	COG0673	inositol 2-dehydrogenase activity
S101441_01283	COG2318	DinB family
S101441_01284	COG1279	arginine transmembrane transporter activity
S101441_01285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101441_01286	COG1357	PFAM Pentapeptide repeats (8 copies)
S101441_01287	COG2267	carboxylic ester hydrolase activity
S101441_01288	COG0454	-acetyltransferase
S101441_01289	COG2153	protein acetylation
S101441_01290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
S101441_01290	COG0646	methionine synthase
S101441_01291	COG1666	GTP binding
S101441_01292	COG2996	Protein conserved in bacteria
S101441_01296	COG1695	Transcriptional regulator
S101441_01299	COG3227	Zinc metalloprotease (Elastase)
S101441_01300	COG1307	EDD domain protein, DegV family
S101441_01301	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101441_01305	COG0561	phosphatase activity
S101441_01306	COG1073	alpha beta
S101441_01307	COG2151	metal-sulfur cluster biosynthetic enzyme
S101441_01309	COG0277	FAD linked oxidase domain protein
S101441_01310	COG2271	Major facilitator Superfamily
S101441_01311	COG2271	Major facilitator Superfamily
S101441_01312	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
S101441_01315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101441_01316	COG0505	Belongs to the CarA family
S101441_01317	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101441_01318	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
S101441_01319	COG2801	Transposase and inactivated derivatives
S101441_01323	COG2267	carboxylic ester hydrolase activity
S101441_01325	COG1744	ABC transporter substrate-binding protein PnrA-like
S101441_01328	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101441_01329	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101441_01330	COG5504	Zn-dependent protease
S101441_01331	COG0444	Belongs to the ABC transporter superfamily
S101441_01332	COG4608	Belongs to the ABC transporter superfamily
S101441_01334	COG0601	transmembrane transport
S101441_01335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101441_01337	COG0180	Tryptophanyl-tRNA synthetase
S101441_01338	COG4166	transmembrane transport
S101441_01339	COG0601	transmembrane transport
S101441_01340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101441_01341	COG0444	Belongs to the ABC transporter superfamily
S101441_01342	COG4608	Belongs to the ABC transporter superfamily
S101441_01343	COG2814	Major facilitator Superfamily
S101441_01344	COG0456	acetyltransferase
S101441_01345	COG0456	acetyltransferase
S101441_01346	COG1393	Belongs to the ArsC family
S101441_01347	COG0861	Integral membrane protein TerC family
S101441_01348	COG4862	establishment of competence for transformation
S101441_01349	COG4469	Competence protein
S101441_01350	COG1164	Oligoendopeptidase f
S101441_01353	COG2346	COG2346, Truncated hemoglobins
S101441_01354	COG0741	lytic transglycosylase activity
S101441_01355	COG4116	CYTH
S101441_01357	COG2357	RelA SpoT domain protein
S101441_01358	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101441_01359	COG0564	pseudouridine synthase activity
S101441_01360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
S101441_01361	COG0569	domain protein
S101441_01361	COG0475	glutathione-regulated potassium exporter activity
S101441_01362	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
S101441_01363	COG0352	thiamine-phosphate diphosphorylase activity
S101441_01364	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101441_01365	COG2104	thiamine diphosphate biosynthetic process
S101441_01366	COG2022	thiamine diphosphate biosynthetic process
S101441_01367	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101441_01368	COG0351	phosphomethylpyrimidine kinase
S101441_01369	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
S101441_01380	COG0210	DNA helicase
S101441_01382	COG2153	protein acetylation
S101441_01383	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S101441_01384	COG2382	esterase
S101441_01385	COG0626	cystathionine gamma-synthase activity
S101441_01386	COG0626	cystathionine gamma-synthase activity
S101441_01387	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_01388	COG5505	Protein of unknown function (DUF819)
S101441_01392	COG2856	Zn peptidase
S101441_01396	COG1396	sequence-specific DNA binding
S101441_01401	COG2801	Transposase and inactivated derivatives
S101441_01424	COG0457	Tetratricopeptide repeat
S101441_01425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101441_01427	COG3711	transcriptional antiterminator
S101441_01427	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_01428	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101441_01428	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_01428	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101441_01429	COG1482	cell wall glycoprotein biosynthetic process
S101441_01431	COG3328	transposase activity
S101441_01432	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_01434	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S101441_01437	COG0109	protoheme IX farnesyltransferase activity
S101441_01439	COG0726	polysaccharide deacetylase
S101441_01442	COG5504	Zn-dependent protease
S101441_01443	COG5504	Zn-dependent protease
S101441_01444	COG2205	protein histidine kinase activity
S101441_01446	COG3383	formate dehydrogenase (NAD+) activity
S101441_01447	COG2427	Protein of unknown function (DUF1641)
S101441_01449	COG1051	belongs to the nudix hydrolase family
S101441_01451	COG2124	cytochrome p450
S101441_01452	COG1819	glycosyl
S101441_01454	COG1587	Uroporphyrinogen-III synthase
S101441_01459	COG0390	transport system, permease component
S101441_01460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101441_01461	COG0697	spore germination
S101441_01462	COG4297	protein containing double-stranded beta helix domain
S101441_01463	COG4297	protein containing double-stranded beta helix domain
S101441_01465	COG1252	NADH dehydrogenase
S101441_01466	COG1904	glucuronate isomerase
S101441_01467	COG2211	Major facilitator Superfamily
S101441_01468	COG2211	Major facilitator Superfamily
S101441_01469	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
S101441_01470	COG1063	alcohol dehydrogenase
S101441_01471	COG1312	Catalyzes the dehydration of D-mannonate
S101441_01472	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_01473	COG2271	Major facilitator Superfamily
S101441_01474	COG1609	Transcriptional regulator
S101441_01475	COG0246	Mannitol dehydrogenase
S101441_01476	COG2721	sulfolactate sulfo-lyase activity
S101441_01477	COG0730	response to heat
S101441_01480	COG2318	DinB family
S101441_01481	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S101441_01482	COG2801	Transposase and inactivated derivatives
S101441_01484	COG0457	Tetratricopeptide repeat
S101441_01486	COG2350	Protein conserved in bacteria
S101441_01487	COG1388	LysM domain
S101441_01487	COG3409	Peptidoglycan-binding domain 1 protein
S101441_01487	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101441_01489	COG4195	phage-related replication protein
S101441_01490	COG3546	catalase activity
S101441_01491	COG2856	Zn peptidase
S101441_01492	COG1396	sequence-specific DNA binding
S101441_01494	COG1522	sequence-specific DNA binding
S101441_01495	COG1484	DNA-dependent DNA replication
S101441_01500	COG1595	DNA-templated transcription, initiation
S101441_01501	COG3728	DNA packaging
S101441_01501	COG5484	DNA packaging
S101441_01502	COG1783	phage Terminase large subunit
S101441_01503	COG5518	Phage portal protein
S101441_01504	COG0338	D12 class N6 adenine-specific DNA methyltransferase
S101441_01505	COG4653	Phage capsid family
S101441_01513	COG3953	SLT domain
S101441_01513	COG5412	phage tail tape measure protein
S101441_01513	COG5412	phage tail tape measure protein
S101441_01513	COG3953	SLT domain
S101441_01513	COG3953	SLT domain
S101441_01513	COG5412	phage tail tape measure protein
S101441_01514	COG1652	LysM domain
S101441_01515	COG4193	domain, Protein
S101441_01517	COG3628	GPW Gp25 family protein
S101441_01518	COG3299	homolog of phage Mu protein gp47
S101441_01519	COG3778	Protein conserved in bacteria
S101441_01527	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101441_01527	COG3409	Peptidoglycan-binding domain 1 protein
S101441_01530	COG0306	phosphate transporter
S101441_01531	COG1392	Phosphate transport regulator
S101441_01534	COG0531	amino acid
S101441_01535	COG0346	lactoylglutathione lyase activity
S101441_01536	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101441_01537	COG0463	Glycosyl transferase, family 2
S101441_01539	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101441_01540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101441_01541	COG2362	D-Aminopeptidase
S101441_01542	COG0601	transmembrane transport
S101441_01543	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101441_01544	COG0444	Belongs to the ABC transporter superfamily
S101441_01545	COG4166	transmembrane transport
S101441_01547	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101441_01548	COG4948	Mandelate Racemase Muconate Lactonizing
S101441_01549	COG0791	NLP P60 protein
S101441_01550	COG4608	Belongs to the ABC transporter superfamily
S101441_01551	COG2706	6-phosphogluconolactonase activity
S101441_01552	COG1834	amidinotransferase
S101441_01553	COG1607	acyl-coa hydrolase
S101441_01554	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S101441_01554	COG1017	nitric oxide dioxygenase activity
S101441_01556	COG2323	membrane
S101441_01557	COG2318	DinB family
S101441_01558	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_01559	COG2076	Multidrug Resistance protein
S101441_01560	COG2076	Multidrug Resistance protein
S101441_01561	COG0788	formyltetrahydrofolate deformylase activity
S101441_01562	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101441_01563	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
S101441_01564	COG1764	response to oxidative stress
S101441_01565	COG1846	Transcriptional regulator
S101441_01566	COG1764	response to oxidative stress
S101441_01567	COG0590	tRNA wobble adenosine to inosine editing
S101441_01568	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101441_01569	COG1404	Belongs to the peptidase S8 family
S101441_01570	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_01571	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101441_01572	COG1122	ATPase activity
S101441_01573	COG4721	ABC-type cobalt transport system, permease component
S101441_01575	COG0745	RESPONSE REGULATOR receiver
S101441_01576	COG3850	Histidine kinase
S101441_01576	COG5002	protein histidine kinase activity
S101441_01577	COG3212	peptidase
S101441_01578	COG3212	peptidase
S101441_01581	COG2239	Acts as a magnesium transporter
S101441_01582	COG0789	Transcriptional regulator
S101441_01585	COG1846	Transcriptional regulator
S101441_01586	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101441_01587	COG0726	polysaccharide deacetylase
S101441_01588	COG1408	metallophosphoesterase
S101441_01590	COG0463	Glycosyl transferase, family 2
S101441_01591	COG1793	dna ligase
S101441_01591	COG3285	dna ligase
S101441_01592	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
S101441_01593	COG3300	MHYT domain
S101441_01593	COG5001	Diguanylate cyclase
S101441_01594	COG0586	Pfam SNARE associated Golgi protein
S101441_01595	COG0861	Integral membrane protein TerC family
S101441_01596	COG1191	sigma factor activity
S101441_01600	COG0501	Belongs to the peptidase M48B family
S101441_01601	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S101441_01604	COG3594	Acyltransferase
S101441_01605	COG5002	protein histidine kinase activity
S101441_01606	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101441_01608	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
S101441_01609	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
S101441_01610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101441_01611	COG0436	Aminotransferase
S101441_01612	COG1850	ribulose-bisphosphate carboxylase activity
S101441_01613	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
S101441_01614	COG0235	Class ii aldolase
S101441_01615	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
S101441_01616	COG3339	Conserved Protein
S101441_01619	COG3852	Histidine kinase
S101441_01620	COG1846	Transcriptional regulator
S101441_01621	COG1360	Flagellar Motor Protein
S101441_01622	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101441_01623	COG0542	response to heat
S101441_01624	COG3949	Membrane
S101441_01625	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
S101441_01626	COG0720	synthase
S101441_01627	COG0602	queuosine metabolic process
S101441_01628	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
S101441_01630	COG4873	Protein conserved in bacteria
S101441_01632	COG3773	Cell wall hydrolase
S101441_01633	COG2244	polysaccharide biosynthetic process
S101441_01634	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_01635	COG2217	Heavy metal translocating P-type atpase
S101441_01637	COG0006	proline dipeptidase activity
S101441_01638	COG1609	Transcriptional regulator
S101441_01639	COG3711	transcriptional antiterminator
S101441_01640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_01640	COG1263	PTS System
S101441_01640	COG2190	(PTS) system
S101441_01641	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_01642	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
S101441_01644	COG1533	DNA photolyase activity
S101441_01645	COG0456	acetyltransferase
S101441_01646	COG0840	transmembrane signaling receptor activity
S101441_01647	COG2084	Dehydrogenase
S101441_01650	COG3328	transposase activity
S101441_01651	COG2340	Cysteine-rich secretory protein family
S101441_01652	COG0768	penicillin binding
S101441_01653	COG4191	Histidine kinase
S101441_01654	COG0436	Aminotransferase
S101441_01656	COG0835	chemotaxis
S101441_01656	COG0784	Response regulator, receiver
S101441_01658	COG2814	Major facilitator Superfamily
S101441_01659	COG1376	ErfK ybiS ycfS ynhG family protein
S101441_01660	COG1408	metallophosphoesterase
S101441_01661	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_01662	COG2200	EAL domain
S101441_01663	COG4703	Protein of unknown function (DUF1797)
S101441_01664	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
S101441_01666	COG0517	IMP dehydrogenase activity
S101441_01667	COG0583	DNA-binding transcription factor activity
S101441_01668	COG0716	FMN binding
S101441_01670	COG0716	FMN binding
S101441_01671	COG2171	N-acyltransferase activity
S101441_01672	COG1473	amidohydrolase
S101441_01674	COG0668	transmembrane transport
S101441_01675	COG0450	alkyl hydroperoxide reductase
S101441_01676	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_01678	COG2801	Transposase and inactivated derivatives
S101441_01681	COG0746	molybdenum cofactor guanylyltransferase activity
S101441_01682	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101441_01683	COG0303	'Molybdopterin
S101441_01684	COG1763	Mo-molybdopterin cofactor biosynthetic process
S101441_01685	COG0314	molybdopterin synthase activity
S101441_01686	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
S101441_01687	COG1132	(ABC) transporter
S101441_01688	COG1132	(ABC) transporter
S101441_01690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S101441_01691	COG1136	(ABC) transporter
S101441_01692	COG0577	efflux transmembrane transporter activity
S101441_01693	COG1349	DNA-binding transcription factor activity
S101441_01694	COG1105	Belongs to the carbohydrate kinase PfkB family
S101441_01695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101441_01695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_01695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101441_01696	COG0681	Belongs to the peptidase S26 family
S101441_01698	COG0488	(ABC) transporter
S101441_01699	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101441_01701	COG2309	aminopeptidase activity
S101441_01703	COG1077	Cell shape determining protein MreB Mrl
S101441_01704	COG2002	toxin-antitoxin pair type II binding
S101441_01705	COG3852	Histidine kinase
S101441_01706	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
S101441_01706	COG2105	PFAM AIG2 family protein
S101441_01707	COG0569	domain protein
S101441_01708	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S101441_01709	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101441_01711	COG0561	phosphatase activity
S101441_01712	COG0242	peptide deformylase activity
S101441_01714	COG0497	DNA recombination
S101441_01715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101441_01716	COG0022	dehydrogenase e1 component
S101441_01717	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101441_01718	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101441_01719	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_01722	COG1982	Orn Lys Arg decarboxylase major
S101441_01723	COG4476	Belongs to the UPF0223 family
S101441_01724	COG4493	Belongs to the UPF0637 family
S101441_01726	COG0483	inositol monophosphate 1-phosphatase activity
S101441_01728	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
S101441_01732	COG1595	DNA-templated transcription, initiation
S101441_01738	COG4896	Protein conserved in bacteria
S101441_01740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
S101441_01741	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101441_01742	COG2066	Belongs to the glutaminase family
S101441_01743	COG4838	Belongs to the UPF0358 family
S101441_01744	COG0772	Belongs to the SEDS family
S101441_01745	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
S101441_01748	COG1612	heme a metabolic process
S101441_01749	COG0109	protoheme IX farnesyltransferase activity
S101441_01750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101441_01750	COG2010	Cytochrome c
S101441_01751	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101441_01752	COG1845	cytochrome c oxidase, subunit III
S101441_01753	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S101441_01754	COG3336	cytochrome c oxidase
S101441_01756	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
S101441_01757	COG2340	Cysteine-rich secretory protein family
S101441_01760	COG3679	Belongs to the UPF0342 family
S101441_01761	COG4471	UPF0298 protein
S101441_01762	COG0742	ribosomal rna small subunit methyltransferase
S101441_01763	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
S101441_01764	COG3314	Sporulation integral membrane protein YlbJ
S101441_01765	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101441_01766	COG3480	Lon protease (S16) C-terminal proteolytic domain
S101441_01767	COG1323	Belongs to the UPF0348 family
S101441_01769	COG1399	metal-binding, possibly nucleic acid-binding protein
S101441_01770	COG0333	Belongs to the bacterial ribosomal protein bL32 family
S101441_01772	COG0454	-acetyltransferase
S101441_01773	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101441_01774	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
S101441_01775	COG2001	Belongs to the MraZ family
S101441_01776	COG0275	rRNA processing
S101441_01777	COG4839	cell division protein FtsL
S101441_01779	COG0768	penicillin binding
S101441_01780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
S101441_01781	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S101441_01782	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S101441_01783	COG0772	Belongs to the SEDS family
S101441_01784	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101441_01785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
S101441_01786	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
S101441_01787	COG3879	Bacterial protein of unknown function (DUF881)
S101441_01788	COG3879	Bacterial protein of unknown function (DUF881)
S101441_01789	COG3856	small basic protein
S101441_01790	COG0849	cell division
S101441_01791	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
S101441_01792	COG1404	Belongs to the peptidase S8 family
S101441_01792	COG4412	M6 family metalloprotease domain protein
S101441_01795	COG1191	sigma factor activity
S101441_01796	COG1191	sigma factor activity
S101441_01797	COG1119	ATPase activity
S101441_01798	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101441_01799	COG1873	PFAM PRC-barrel domain
S101441_01801	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
S101441_01802	COG1799	cell septum assembly
S101441_01803	COG0762	integral membrane protein
S101441_01804	COG2302	S4 RNA-binding domain
S101441_01805	COG3599	regulation of cell shape
S101441_01806	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
S101441_01809	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101441_01810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
S101441_01811	COG0564	pseudouridine synthase activity
S101441_01812	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
S101441_01813	COG2233	PERMEase
S101441_01814	COG0540	Belongs to the ATCase OTCase family
S101441_01815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S101441_01816	COG0505	Belongs to the CarA family
S101441_01817	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101441_01818	COG0543	2 iron, 2 sulfur cluster binding
S101441_01819	COG0167	dihydroorotate dehydrogenase activity
S101441_01820	COG0284	orotidine-5'-phosphate decarboxylase activity
S101441_01821	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
S101441_01822	COG0175	sulfate reduction
S101441_01823	COG0306	phosphate transporter
S101441_01824	COG2046	Belongs to the sulfate adenylyltransferase family
S101441_01825	COG0529	Catalyzes the synthesis of activated sulfate
S101441_01826	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101441_01827	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
S101441_01828	COG1648	precorrin-2 dehydrogenase activity
S101441_01830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S101441_01831	COG1561	YicC-like family, N-terminal region
S101441_01832	COG2052	Domain of unknown function (DUF370)
S101441_01833	COG0194	GDP metabolic process
S101441_01834	COG1758	RNA polymerase activity
S101441_01835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101441_01836	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101441_01837	COG0242	peptide deformylase activity
S101441_01838	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
S101441_01839	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S101441_01839	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
S101441_01840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
S101441_01841	COG0631	protein serine/threonine phosphatase activity
S101441_01842	COG2815	serine threonine protein kinase
S101441_01842	COG0515	serine threonine protein kinase
S101441_01843	COG1162	GTPase activity
S101441_01844	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S101441_01845	COG1564	THIamine pyrophosphokinase
S101441_01846	COG0227	Belongs to the bacterial ribosomal protein bL28 family
S101441_01847	COG1302	Protein conserved in bacteria
S101441_01848	COG1461	Dihydroxyacetone kinase
S101441_01849	COG1760	l-serine dehydratase
S101441_01850	COG1760	l-serine dehydratase
S101441_01851	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
S101441_01852	COG1349	DNA-binding transcription factor activity
S101441_01852	COG2050	protein possibly involved in aromatic compounds catabolism
S101441_01853	COG0416	fatty acid biosynthetic process
S101441_01854	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S101441_01855	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_01856	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101441_01857	COG0571	ribonuclease III activity
S101441_01858	COG1196	nuclear chromosome segregation
S101441_01859	COG0552	protein localization to endoplasmic reticulum
S101441_01861	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
S101441_01862	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
S101441_01863	COG0228	four-way junction DNA binding
S101441_01864	COG1837	Belongs to the UPF0109 family
S101441_01866	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
S101441_01867	COG0336	Belongs to the RNA methyltransferase TrmD family
S101441_01868	COG0335	large ribosomal subunit rRNA binding
S101441_01869	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101441_01870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
S101441_01872	COG2257	FlhB HrpN YscU SpaS Family
S101441_01873	COG0045	succinate-CoA ligase (ADP-forming) activity
S101441_01874	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
S101441_01875	COG0758	DNA mediated transformation
S101441_01876	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101441_01877	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
S101441_01878	COG4974	Belongs to the 'phage' integrase family
S101441_01879	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
S101441_01880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
S101441_01881	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S101441_01882	COG1815	bacterial-type flagellum-dependent cell motility
S101441_01883	COG1558	bacterial-type flagellum-dependent cell motility
S101441_01884	COG1677	Flagellar hook-basal body complex protein FliE
S101441_01885	COG1766	The M ring may be actively involved in energy transduction
S101441_01886	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101441_01887	COG1317	bacterial-type flagellum organization
S101441_01888	COG1157	protein secretion by the type III secretion system
S101441_01889	COG2882	bacterial-type flagellum organization
S101441_01890	COG3334	PFAM MgtE intracellular
S101441_01891	COG3144	bacterial-type flagellum assembly
S101441_01892	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
S101441_01893	COG4786	Flagellar basal body rod
S101441_01894	COG1580	Controls the rotational direction of flagella during chemotaxis
S101441_01895	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101441_01896	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101441_01896	COG1776	CheC inhibitor of MCP methylation
S101441_01897	COG2201	protein-glutamate methylesterase activity
S101441_01898	COG3190	flagellar
S101441_01899	COG1338	Plays a role in the flagellum-specific transport system
S101441_01900	COG1987	bacterial-type flagellum assembly
S101441_01901	COG1684	flagellar biosynthetic protein fliR
S101441_01902	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101441_01903	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101441_01904	COG1419	protein localization to endoplasmic reticulum
S101441_01905	COG0455	bacterial-type flagellum organization
S101441_01906	COG2201	protein-glutamate methylesterase activity
S101441_01907	COG0643	Histidine kinase
S101441_01907	COG2198	Histidine kinase
S101441_01908	COG0835	chemotaxis
S101441_01909	COG1776	CheC inhibitor of MCP methylation
S101441_01910	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
S101441_01911	COG1191	sigma factor activity
S101441_01913	COG0052	Belongs to the universal ribosomal protein uS2 family
S101441_01914	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
S101441_01915	COG0528	UMP kinase activity
S101441_01916	COG0233	cytoplasmic translational termination
S101441_01917	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
S101441_01918	COG4589	Belongs to the CDS family
S101441_01919	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
S101441_01920	COG0750	zinc metalloprotease
S101441_01921	COG0442	prolyl-tRNA aminoacylation
S101441_01922	COG2176	DNA-directed DNA polymerase activity
S101441_01923	COG0779	Required for maturation of 30S ribosomal subunits
S101441_01924	COG0195	Participates in both transcription termination and antitermination
S101441_01925	COG2740	Nucleic-acid-binding protein implicated in transcription termination
S101441_01926	COG1358	cellular component organization or biogenesis
S101441_01927	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
S101441_01928	COG1550	Protein conserved in bacteria
S101441_01929	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
S101441_01930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
S101441_01931	COG0196	riboflavin kinase activity
S101441_01932	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
S101441_01933	COG1185	polyribonucleotide nucleotidyltransferase activity
S101441_01934	COG0726	polysaccharide deacetylase
S101441_01935	COG0612	Peptidase, M16
S101441_01936	COG1873	PFAM PRC-barrel domain
S101441_01937	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101441_01938	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101441_01939	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
S101441_01940	COG0527	aspartate kinase activity
S101441_01941	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
S101441_01942	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101441_01943	COG0740	serine-type endopeptidase activity
S101441_01945	COG4980	gas vesicle protein
S101441_01945	COG1674	ftsk spoiiie
S101441_01946	COG2188	Transcriptional regulator
S101441_01947	COG2814	Major facilitator Superfamily
S101441_01948	COG0612	Peptidase, M16
S101441_01949	COG0612	Peptidase, M16
S101441_01950	COG0300	oxidoreductase activity
S101441_01953	COG1426	Protein conserved in bacteria
S101441_01954	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
S101441_01955	COG1058	Belongs to the CinA family
S101441_01955	COG1546	Belongs to the CinA family
S101441_01956	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
S101441_01957	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101441_01958	COG1418	mRNA catabolic process
S101441_01959	COG1692	metallophosphoesterase
S101441_01960	COG2359	stage V sporulation protein S
S101441_01961	COG1063	alcohol dehydrogenase
S101441_01962	COG0156	8-amino-7-oxononanoate synthase activity
S101441_01964	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S101441_01965	COG4550	Control of competence regulator ComK, YlbF/YmcA
S101441_01967	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
S101441_01968	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
S101441_01974	COG0582	viral genome integration into host DNA
S101441_01985	COG3328	transposase activity
S101441_01988	COG3226	Transcriptional regulator
S101441_01990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101441_01991	COG1404	Belongs to the peptidase S8 family
S101441_01993	COG4195	phage-related replication protein
S101441_01994	COG1764	response to oxidative stress
S101441_01995	COG2076	Multidrug Resistance protein
S101441_01996	COG2076	Multidrug Resistance protein
S101441_01999	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
S101441_02000	COG1923	regulation of RNA biosynthetic process
S101441_02003	COG1780	Probably involved in ribonucleotide reductase function
S101441_02004	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101441_02005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101441_02006	COG4112	unkown
S101441_02007	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101441_02008	COG0464	growth
S101441_02009	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
S101441_02010	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
S101441_02011	COG0789	Transcriptional regulator
S101441_02012	COG0174	glutamine synthetase
S101441_02015	COG5444	nuclease activity
S101441_02021	COG4282	regulation of fungal-type cell wall biogenesis
S101441_02024	COG3328	transposase activity
S101441_02026	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_02030	COG3655	Transcriptional regulator
S101441_02035	COG0135	phosphoribosylanthranilate isomerase activity
S101441_02036	COG2211	Major facilitator Superfamily
S101441_02037	COG3507	Belongs to the glycosyl hydrolase 43 family
S101441_02038	COG1940	carbohydrate kinase activity
S101441_02039	COG2115	Belongs to the xylose isomerase family
S101441_02040	COG1070	Carbohydrate kinase
S101441_02041	COG3328	transposase activity
S101441_02042	COG1525	nuclease
S101441_02043	COG2814	Major facilitator Superfamily
S101441_02044	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101441_02046	COG0756	dUTP diphosphatase activity
S101441_02055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101441_02057	COG3832	glyoxalase III activity
S101441_02060	COG0697	spore germination
S101441_02061	COG0697	spore germination
S101441_02068	COG4195	phage-related replication protein
S101441_02070	COG0346	lactoylglutathione lyase activity
S101441_02071	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
S101441_02072	COG1388	LysM domain
S101441_02073	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101441_02074	COG4224	UPF0291 protein
S101441_02075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
S101441_02077	COG3763	UPF0154 protein
S101441_02079	COG0785	Cytochrome C biogenesis protein
S101441_02080	COG2201	protein-glutamate methylesterase activity
S101441_02081	COG4846	Membrane protein involved in cytochrome C biogenesis
S101441_02082	COG2801	Transposase and inactivated derivatives
S101441_02085	COG0071	Belongs to the small heat shock protein (HSP20) family
S101441_02088	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
S101441_02089	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_02093	COG0824	Thioesterase
S101441_02095	COG4841	protein insertion into membrane
S101441_02096	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
S101441_02097	COG1832	CoA-binding protein
S101441_02098	COG0187	DNA topoisomerase II activity
S101441_02099	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101441_02102	COG1115	amino acid carrier protein
S101441_02103	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
S101441_02105	COG5520	Belongs to the glycosyl hydrolase 30 family
S101441_02106	COG5520	Belongs to the glycosyl hydrolase 30 family
S101441_02107	COG3507	Belongs to the glycosyl hydrolase 43 family
S101441_02108	COG3507	Belongs to the glycosyl hydrolase 43 family
S101441_02109	COG2246	polysaccharide biosynthetic process
S101441_02110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101441_02111	COG0586	Pfam SNARE associated Golgi protein
S101441_02112	COG2404	hydrolase activity, acting on ester bonds
S101441_02113	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101441_02114	COG1024	Enoyl-CoA hydratase
S101441_02115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S101441_02116	COG0511	ligase activity, forming carbon-carbon bonds
S101441_02117	COG0439	Biotin carboxylase
S101441_02118	COG0318	PFAM AMP-dependent synthetase and ligase
S101441_02119	COG1960	acyl-CoA dehydrogenase activity
S101441_02120	COG1649	PFAM Uncharacterised BCR, COG1649
S101441_02122	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_02122	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101441_02123	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_02123	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101441_02124	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_02125	COG2027	D-alanyl-D-alanine carboxypeptidase
S101441_02126	COG2017	converts alpha-aldose to the beta-anomer
S101441_02127	COG0534	Mate efflux family protein
S101441_02130	COG0582	viral genome integration into host DNA
S101441_02131	COG0166	Belongs to the GPI family
S101441_02132	COG0405	Gamma-glutamyltransferase
S101441_02133	COG0583	DNA-binding transcription factor activity
S101441_02134	COG0604	alcohol dehydrogenase
S101441_02135	COG0493	'glutamate synthase
S101441_02136	COG0067	glutamate synthase
S101441_02136	COG0070	glutamate synthase
S101441_02136	COG0069	glutamate synthase activity
S101441_02137	COG0583	DNA-binding transcription factor activity
S101441_02138	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101441_02139	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101441_02140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101441_02142	COG0300	oxidoreductase activity
S101441_02143	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101441_02145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_02148	COG1131	(ABC) transporter
S101441_02150	COG2814	Major facilitator Superfamily
S101441_02151	COG1070	Carbohydrate kinase
S101441_02152	COG2323	membrane
S101441_02153	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101441_02156	COG2323	membrane
S101441_02159	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101441_02163	COG3546	catalase activity
S101441_02167	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101441_02171	COG0840	transmembrane signaling receptor activity
S101441_02171	COG5278	phosphoserine phosphatase activity
S101441_02172	COG2368	4-hydroxyphenylacetate
S101441_02173	COG4305	rare lipoprotein A
S101441_02174	COG3619	membrane
S101441_02175	COG3866	Pectate lyase
S101441_02176	COG3866	Pectate lyase
S101441_02177	COG2135	peptidase activity
S101441_02179	COG2140	Oxalate decarboxylase
S101441_02183	COG2720	vancomycin resistance protein
S101441_02185	COG3655	Transcriptional regulator
S101441_02186	COG3739	integral membrane protein
S101441_02187	COG0583	DNA-binding transcription factor activity
S101441_02188	COG0697	spore germination
S101441_02190	COG0693	protein deglycase activity
S101441_02191	COG2367	Beta-lactamase
S101441_02194	COG3848	Pyruvate phosphate dikinase
S101441_02194	COG0574	Belongs to the PEP-utilizing enzyme family
S101441_02195	COG0726	polysaccharide deacetylase
S101441_02196	COG2314	TM2 domain
S101441_02197	COG1396	sequence-specific DNA binding
S101441_02212	COG3655	Transcriptional regulator
S101441_02219	COG0457	Tetratricopeptide repeat
S101441_02221	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_02223	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101441_02224	COG2226	methyltransferase
S101441_02225	COG2211	Major facilitator Superfamily
S101441_02226	COG3328	transposase activity
S101441_02227	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101441_02228	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101441_02229	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101441_02233	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101441_02237	COG5444	nuclease activity
S101441_02238	COG4282	regulation of fungal-type cell wall biogenesis
S101441_02239	COG1231	oxidoreductase activity
S101441_02240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101441_02241	COG0662	Cupin 2, conserved barrel domain protein
S101441_02241	COG2207	Transcriptional regulator
S101441_02242	COG0456	acetyltransferase
S101441_02243	COG1309	transcriptional regulator
S101441_02244	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101441_02245	COG3708	Transcriptional regulator
S101441_02246	COG2378	regulation of single-species biofilm formation
S101441_02248	COG0640	Transcriptional regulator
S101441_02249	COG0741	lytic transglycosylase activity
S101441_02252	COG2322	membrane
S101441_02255	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101441_02256	COG3239	Fatty acid desaturase
S101441_02257	COG4585	Histidine kinase
S101441_02258	COG2197	response regulator
S101441_02260	COG1388	LysM domain
S101441_02260	COG3584	3D domain protein
S101441_02261	COG0514	ATP-dependent DNA helicase (RecQ)
S101441_02262	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101441_02263	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101441_02266	COG0071	Belongs to the small heat shock protein (HSP20) family
S101441_02271	COG1012	belongs to the aldehyde dehydrogenase family
S101441_02272	COG1657	PFAM Prenyltransferase squalene oxidase
S101441_02273	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101441_02274	COG0733	neurotransmitter:sodium symporter activity
S101441_02275	COG0385	Bile acid
S101441_02276	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101441_02277	COG0567	Dehydrogenase, E1 component
S101441_02278	COG4548	von Willebrand factor, type A
S101441_02279	COG0714	Associated with various cellular activities
S101441_02280	COG2032	superoxide dismutase activity
S101441_02281	COG0791	NLP P60 protein
S101441_02281	COG1388	LysM domain
S101441_02282	COG1819	glycosyl
S101441_02283	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101441_02285	COG0534	Mate efflux family protein
S101441_02286	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_02287	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101441_02288	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101441_02290	COG2962	Rard protein
S101441_02295	COG2610	gluconate transmembrane transporter activity
S101441_02296	COG1942	4-Oxalocrotonate Tautomerase
S101441_02297	COG1733	regulation of RNA biosynthetic process
S101441_02298	COG0778	Nitroreductase
S101441_02299	COG0400	carboxylic ester hydrolase activity
S101441_02300	COG0346	lactoylglutathione lyase activity
S101441_02302	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101441_02303	COG0793	Belongs to the peptidase S41A family
S101441_02303	COG3409	Peptidoglycan-binding domain 1 protein
S101441_02304	COG2226	methyltransferase
S101441_02306	COG1876	peptidase activity
S101441_02307	COG0813	purine-nucleoside phosphorylase activity
S101441_02310	COG0671	phosphoesterase, PA-phosphatase related
S101441_02314	COG4479	Belongs to the UPF0346 family
S101441_02316	COG1509	lysine 2,3-aminomutase activity
S101441_02317	COG0456	acetyltransferase
S101441_02318	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101441_02319	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101441_02320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101441_02321	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101441_02322	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101441_02324	COG0456	acetyltransferase
S101441_02325	COG0463	Glycosyl transferase, family 2
S101441_02328	COG4641	Protein conserved in bacteria
S101441_02329	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
S101441_02330	COG1086	Polysaccharide biosynthesis protein
S101441_02331	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
S101441_02332	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
S101441_02333	COG1846	Transcriptional regulator
S101441_02334	COG0534	Mate efflux family protein
S101441_02336	COG4698	Protein conserved in bacteria
S101441_02337	COG2755	lipolytic protein G-D-S-L family
S101441_02338	COG1999	signal sequence binding
S101441_02340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101441_02341	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101441_02342	COG1272	protein, Hemolysin III
S101441_02343	COG0204	Acyl-transferase
S101441_02344	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101441_02345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S101441_02347	COG2521	methyltransferase
S101441_02347	COG2136	Putative SAM-dependent methyltransferase
S101441_02349	COG0129	dihydroxy-acid dehydratase activity
S101441_02350	COG1413	lyase activity
S101441_02351	COG1418	mRNA catabolic process
S101441_02352	COG0386	Belongs to the glutathione peroxidase family
S101441_02353	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
S101441_02354	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101441_02355	COG1278	Cold shock
S101441_02359	COG0328	RNA-DNA hybrid ribonuclease activity
S101441_02360	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
S101441_02361	COG0328	RNA-DNA hybrid ribonuclease activity
S101441_02363	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101441_02366	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101441_02368	COG1755	Isoprenylcysteine carboxyl methyltransferase
S101441_02369	COG3424	synthase
S101441_02370	COG3424	synthase
S101441_02371	COG2233	PERMEase
S101441_02372	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101441_02373	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
S101441_02375	COG0800	Aldolase
S101441_02376	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101441_02377	COG1609	Transcriptional regulator
S101441_02378	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
S101441_02379	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_02380	COG1199	ATP-dependent helicase activity
S101441_02382	COG0116	Belongs to the methyltransferase superfamily
S101441_02384	COG4474	Belongs to the UPF0398 family
S101441_02385	COG3359	exonuclease
S101441_02386	COG1205	dead DEAH box helicase
S101441_02386	COG1111	helicase
S101441_02387	COG2190	(PTS) system
S101441_02388	COG0071	Belongs to the small heat shock protein (HSP20) family
S101441_02395	COG3331	DNA recombination
S101441_02396	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101441_02396	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101441_02398	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
S101441_02399	COG3935	DnaD domain protein
S101441_02400	COG0017	Asparaginyl-tRNA synthetase
S101441_02401	COG0436	Aminotransferase
S101441_02402	COG5353	protein conserved in bacteria
S101441_02404	COG1199	ATP-dependent helicase activity
S101441_02404	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
S101441_02405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
S101441_02406	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
S101441_02407	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
S101441_02408	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
S101441_02408	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
S101441_02409	COG0617	tRNA 3'-terminal CCA addition
S101441_02410	COG0438	transferase activity, transferring glycosyl groups
S101441_02411	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101441_02412	COG1803	Methylglyoxal synthase
S101441_02413	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
S101441_02414	COG1694	Mazg nucleotide pyrophosphohydrolase
S101441_02415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101441_02417	COG4347	Protein of unknown function (DUF1405)
S101441_02418	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101441_02418	COG2010	Cytochrome c
S101441_02419	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101441_02420	COG0723	plastoquinol--plastocyanin reductase activity
S101441_02422	COG5582	Belongs to the UPF0302 family
S101441_02423	COG0457	Tetratricopeptide repeat
S101441_02424	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
S101441_02425	COG0287	Prephenate dehydrogenase
S101441_02428	COG0133	tryptophan synthase activity
S101441_02429	COG0135	phosphoribosylanthranilate isomerase activity
S101441_02431	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
S101441_02432	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101441_02433	COG4401	Chorismate mutase type I
S101441_02434	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
S101441_02435	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
S101441_02436	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
S101441_02437	COG0105	UTP biosynthetic process
S101441_02438	COG0142	geranyltranstransferase activity
S101441_02439	COG2226	methyltransferase
S101441_02440	COG0142	geranyltranstransferase activity
S101441_02442	COG0302	gtp cyclohydrolase
S101441_02445	COG0776	regulation of translation
S101441_02446	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101441_02449	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
S101441_02450	COG1160	GTP binding
S101441_02455	COG2801	Transposase and inactivated derivatives
S101441_02457	COG1304	FMN binding
S101441_02458	COG0539	negative regulation of cytoplasmic translation
S101441_02459	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
S101441_02461	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
S101441_02462	COG2959	enzyme of heme biosynthesis
S101441_02463	COG3773	Cell wall hydrolase
S101441_02463	COG3409	Peptidoglycan-binding domain 1 protein
S101441_02464	COG2339	peptidase activity
S101441_02465	COG0492	ferredoxin-NADP+ reductase activity
S101441_02466	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101441_02467	COG4862	establishment of competence for transformation
S101441_02468	COG1408	metallophosphoesterase
S101441_02470	COG1388	LysM domain
S101441_02471	COG1266	CAAX protease self-immunity
S101441_02472	COG0514	ATP-dependent DNA helicase (RecQ)
S101441_02473	COG4955	Helix-turn-helix domain
S101441_02474	COG1141	Ferredoxin
S101441_02475	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
S101441_02476	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S101441_02477	COG0710	3-dehydroquinate dehydratase activity
S101441_02480	COG1595	DNA-templated transcription, initiation
S101441_02481	COG5002	protein histidine kinase activity
S101441_02482	COG0745	RESPONSE REGULATOR receiver
S101441_02483	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101441_02484	COG1333	cytochrome c biogenesis protein
S101441_02485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_02486	COG1187	pseudouridine synthase activity
S101441_02487	COG0700	Nucleoside recognition
S101441_02488	COG2715	membrane protein required for spore maturation
S101441_02489	COG1686	Belongs to the peptidase S11 family
S101441_02491	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
S101441_02492	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
S101441_02493	COG1547	Domain of unknown function (DUF309)
S101441_02494	COG0456	acetyltransferase
S101441_02495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
S101441_02496	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101441_02496	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101441_02497	COG0307	riboflavin synthase, alpha
S101441_02498	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101441_02498	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101441_02500	COG0681	Belongs to the peptidase S26 family
S101441_02502	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
S101441_02504	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101441_02505	COG2433	Pfam Transposase IS66
S101441_02511	COG3328	transposase activity
S101441_02521	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101441_02522	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101441_02523	COG4086	secreted protein
S101441_02524	COG0019	diaminopimelate decarboxylase activity
S101441_02525	COG0697	spore germination
S101441_02528	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101441_02532	COG1191	sigma factor activity
S101441_02533	COG2172	sigma factor antagonist activity
S101441_02534	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_02535	COG1686	Belongs to the peptidase S11 family
S101441_02536	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
S101441_02537	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
S101441_02538	COG4974	Belongs to the 'phage' integrase family
S101441_02540	COG0735	belongs to the Fur family
S101441_02541	COG1300	Membrane
S101441_02543	COG0281	malic enzyme
S101441_02544	COG1757	Na H antiporter
S101441_02545	COG1027	Aspartate ammonia-lyase
S101441_02546	COG0252	asparaginase activity
S101441_02547	COG1396	sequence-specific DNA binding
S101441_02548	COG1379	DNA repair
S101441_02549	COG0494	nUDIX hydrolase
S101441_02551	COG0667	Aldo Keto reductase
S101441_02553	COG1073	alpha beta
S101441_02555	COG4918	Iron-sulphur cluster biosynthesis
S101441_02556	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
S101441_02556	COG0456	acetyltransferase
S101441_02557	COG2329	Antibiotic biosynthesis monooxygenase
S101441_02558	COG0456	acetyltransferase
S101441_02560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101441_02562	COG2211	Major facilitator Superfamily
S101441_02564	COG0346	lactoylglutathione lyase activity
S101441_02565	COG1072	(Pantothenic acid kinase))
S101441_02566	COG3048	D-serine ammonia-lyase activity
S101441_02567	COG0300	oxidoreductase activity
S101441_02568	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101441_02569	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101441_02572	COG4187	Peptidase family M20/M25/M40
S101441_02573	COG1902	pentaerythritol trinitrate reductase activity
S101441_02574	COG0596	Alpha beta hydrolase
S101441_02576	COG1234	tRNA 3'-trailer cleavage
S101441_02577	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
S101441_02578	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S101441_02579	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101441_02581	COG0706	membrane insertase activity
S101441_02582	COG3361	conserved protein (COG2071)
S101441_02583	COG2195	Cleaves the N-terminal amino acid of tripeptides
S101441_02584	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101441_02585	COG0346	lactoylglutathione lyase activity
S101441_02586	COG1376	ErfK ybiS ycfS ynhG family protein
S101441_02587	COG4129	membrane
S101441_02588	COG1126	abc transporter atp-binding protein
S101441_02589	COG0765	amino acid transport
S101441_02590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101441_02592	COG1597	lipid kinase activity
S101441_02593	COG2814	Major facilitator Superfamily
S101441_02594	COG0789	Transcriptional regulator
S101441_02594	COG4978	Transcriptional regulator
S101441_02595	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101441_02596	COG0022	dehydrogenase e1 component
S101441_02597	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101441_02598	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101441_02599	COG3426	butyrate kinase activity
S101441_02600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101441_02601	COG0280	phosphate acetyltransferase
S101441_02602	COG3829	transcription factor binding
S101441_02602	COG3290	protein histidine kinase activity
S101441_02604	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
S101441_02605	COG2079	MmgE PrpD family protein
S101441_02606	COG0372	Belongs to the citrate synthase family
S101441_02607	COG1960	acyl-CoA dehydrogenase activity
S101441_02608	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101441_02609	COG0183	Belongs to the thiolase family
S101441_02610	COG0584	glycerophosphoryl diester phosphodiesterase
S101441_02611	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101441_02613	COG1902	pentaerythritol trinitrate reductase activity
S101441_02615	COG0745	RESPONSE REGULATOR receiver
S101441_02616	COG0750	zinc metalloprotease
S101441_02617	COG0497	DNA recombination
S101441_02618	COG1438	arginine binding
S101441_02619	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
S101441_02620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
S101441_02621	COG0142	geranyltranstransferase activity
S101441_02622	COG1722	exodeoxyribonuclease VII activity
S101441_02623	COG1570	exodeoxyribonuclease VII activity
S101441_02624	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
S101441_02625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S101441_02626	COG1302	Protein conserved in bacteria
S101441_02627	COG0439	Biotin carboxylase
S101441_02628	COG0511	ligase activity, forming carbon-carbon bonds
S101441_02636	COG3854	ATPases associated with a variety of cellular activities
S101441_02638	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
S101441_02639	COG0006	proline dipeptidase activity
S101441_02640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
S101441_02642	COG3872	metal-dependent enzyme
S101441_02644	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101441_02645	COG1321	iron dependent repressor
S101441_02646	COG0095	Lipoate-protein ligase
S101441_02647	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101441_02648	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
S101441_02649	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
S101441_02650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
S101441_02651	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101441_02654	COG1396	sequence-specific DNA binding
S101441_02656	COG0681	Belongs to the peptidase S26 family
S101441_02661	COG4940	Competence protein ComGF
S101441_02663	COG4970	Tfp pilus assembly protein FimT
S101441_02664	COG4537	Required for transformation and DNA binding
S101441_02665	COG1459	type II secretion system
S101441_02666	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
S101441_02667	COG0517	IMP dehydrogenase activity
S101441_02668	COG0598	Magnesium transport protein CorA
S101441_02669	COG1253	flavin adenine dinucleotide binding
S101441_02670	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_02672	COG1393	Belongs to the ArsC family
S101441_02676	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101441_02678	COG0011	TIGRFAM Protein of
S101441_02680	COG2866	Carboxypeptidase
S101441_02681	COG1368	sulfuric ester hydrolase activity
S101441_02682	COG1940	carbohydrate kinase activity
S101441_02683	COG4483	Protein conserved in bacteria
S101441_02684	COG0457	Tetratricopeptide repeat
S101441_02684	COG0705	Rhomboid family
S101441_02686	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
S101441_02687	COG0267	Belongs to the bacterial ribosomal protein bL33 family
S101441_02688	COG0438	transferase activity, transferring glycosyl groups
S101441_02691	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101441_02692	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101441_02693	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101441_02694	COG0581	inorganic phosphate transmembrane transporter activity
S101441_02695	COG0573	inorganic phosphate transmembrane transporter activity
S101441_02696	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
S101441_02698	COG0477	Major facilitator Superfamily
S101441_02699	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101441_02700	COG2839	Protein conserved in bacteria
S101441_02701	COG5521	maltodextrose utilization protein MalA
S101441_02702	COG1388	LysM domain
S101441_02703	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
S101441_02704	COG4709	membrane
S101441_02705	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
S101441_02706	COG0735	belongs to the Fur family
S101441_02707	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101441_02709	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
S101441_02710	COG0513	Belongs to the DEAD box helicase family
S101441_02712	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
S101441_02713	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
S101441_02714	COG2384	SAM-dependent methyltransferase
S101441_02715	COG2010	Cytochrome c
S101441_02716	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
S101441_02717	COG0358	DNA primase activity
S101441_02718	COG1671	Belongs to the UPF0178 family
S101441_02719	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
S101441_02720	COG0517	IMP dehydrogenase activity
S101441_02721	COG0751	glycine-tRNA ligase activity
S101441_02722	COG0752	glycyl-tRNA synthetase alpha subunit
S101441_02723	COG1381	Involved in DNA repair and RecF pathway recombination
S101441_02725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
S101441_02726	COG0295	cytidine deaminase activity
S101441_02727	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
S101441_02728	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
S101441_02729	COG1480	7TM receptor with intracellular HD hydrolase
S101441_02731	COG1702	phosphate starvation-inducible protein PhoH
S101441_02732	COG0561	phosphatase activity
S101441_02735	COG4864	UPF0365 protein
S101441_02736	COG1030	water channel activity
S101441_02737	COG1610	YqeY-like protein
S101441_02738	COG0828	Belongs to the bacterial ribosomal protein bS21 family
S101441_02739	COG1283	sodium-dependent phosphate transmembrane transporter activity
S101441_02740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S101441_02741	COG1385	rRNA (uridine-N3-)-methyltransferase activity
S101441_02742	COG2264	protein methyltransferase activity
S101441_02743	COG0484	heat shock protein binding
S101441_02744	COG0443	Heat shock 70 kDa protein
S101441_02745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
S101441_02746	COG1420	regulation of RNA biosynthetic process
S101441_02747	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101441_02748	COG0481	GTPase activity
S101441_02750	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101441_02751	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
S101441_02752	COG0268	Binds directly to 16S ribosomal RNA
S101441_02753	COG1466	dna polymerase III delta subunit
S101441_02755	COG0658	competence protein
S101441_02755	COG2333	competence protein COMEC
S101441_02756	COG2131	deaminase
S101441_02757	COG1596	polysaccharide export
S101441_02757	COG1555	photosystem II stabilization
S101441_02758	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101441_02759	COG2226	methyltransferase
S101441_02760	COG0799	negative regulation of ribosome biogenesis
S101441_02761	COG1713	HD superfamily hydrolase involved in NAD metabolism
S101441_02762	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
S101441_02763	COG1534	Rna-binding protein
S101441_02764	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S101441_02765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101441_02766	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
S101441_02768	COG2755	lipolytic protein G-D-S-L family
S101441_02769	COG3409	Peptidoglycan-binding domain 1 protein
S101441_02769	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101441_02770	COG0398	Pfam SNARE associated Golgi protein
S101441_02771	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
S101441_02773	COG3209	COG3209 Rhs family protein
S101441_02775	COG0114	fumarate hydratase activity
S101441_02776	COG0583	DNA-binding transcription factor activity
S101441_02779	COG0457	Tetratricopeptide repeat
S101441_02780	COG5444	nuclease activity
S101441_02781	COG5444	nuclease activity
S101441_02802	COG0789	Transcriptional regulator
S101441_02802	COG4978	Transcriptional regulator
S101441_02803	COG2814	Major facilitator Superfamily
S101441_02804	COG0456	acetyltransferase
S101441_02805	COG3328	transposase activity
S101441_02806	COG1253	flavin adenine dinucleotide binding
S101441_02808	COG0697	spore germination
S101441_02809	COG0583	DNA-binding transcription factor activity
S101441_02810	COG2072	flavoprotein involved in K transport
S101441_02811	COG1230	cation diffusion facilitator family transporter
S101441_02814	COG1114	Component of the transport system for branched-chain amino acids
S101441_02815	COG1687	branched-chain amino acid
S101441_02816	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
S101441_02817	COG1522	sequence-specific DNA binding
S101441_02818	COG2732	(Barnase) inhibitor
S101441_02819	COG1335	isochorismatase
S101441_02821	COG2318	DinB family
S101441_02823	COG2070	2-Nitropropane dioxygenase
S101441_02824	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
S101441_02827	COG3443	Belongs to the bacterial solute-binding protein 9 family
S101441_02828	COG1595	DNA-templated transcription, initiation
S101441_02829	COG0667	Aldo Keto reductase
S101441_02830	COG3409	Peptidoglycan-binding domain 1 protein
S101441_02831	COG5566	PFAM Mor transcription activator
S101441_02832	COG0596	Alpha beta hydrolase
S101441_02833	COG4991	sh3 domain protein
S101441_02834	COG4991	sh3 domain protein
S101441_02835	COG0346	lactoylglutathione lyase activity
S101441_02837	COG5577	PFAM Coat F domain
S101441_02838	COG1063	alcohol dehydrogenase
S101441_02840	COG5577	PFAM Coat F domain
S101441_02841	COG0789	Transcriptional regulator
S101441_02843	COG1064	alcohol dehydrogenase
S101441_02844	COG0693	protein deglycase activity
S101441_02845	COG1621	beta-fructofuranosidase activity
S101441_02846	COG3716	PTS system mannose fructose sorbose family IID component
S101441_02847	COG3715	PTS system
S101441_02848	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_02849	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_02850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101441_02850	COG3933	PFAM sigma-54 factor interaction domain-containing protein
S101441_02851	COG1113	amino acid transport
S101441_02852	COG1280	lysine exporter protein (LysE YggA)
S101441_02853	COG1378	Sugar-specific transcriptional regulator TrmB
S101441_02854	COG1595	DNA-templated transcription, initiation
S101441_02856	COG2755	lipolytic protein G-D-S-L family
S101441_02856	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
S101441_02857	COG2755	lipolytic protein G-D-S-L family
S101441_02857	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
S101441_02859	COG2124	cytochrome p450
S101441_02859	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101441_02860	COG1309	transcriptional regulator
S101441_02861	COG2226	methyltransferase
S101441_02864	COG2116	formate transmembrane transporter activity
S101441_02866	COG5609	conserved protein (DUF2294)
S101441_02867	COG3383	formate dehydrogenase (NAD+) activity
S101441_02868	COG2427	Protein of unknown function (DUF1641)
S101441_02870	COG0626	cystathionine gamma-synthase activity
S101441_02871	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101441_02872	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
S101441_02873	COG2226	methyltransferase
S101441_02876	COG0768	penicillin binding
S101441_02877	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
S101441_02878	COG0572	uridine kinase
S101441_02882	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101441_02883	COG3906	Belongs to the UPF0473 family
S101441_02884	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
S101441_02885	COG4472	Bacterial protein of unknown function (DUF965)
S101441_02886	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
S101441_02887	COG0628	permease
S101441_02888	COG1126	abc transporter atp-binding protein
S101441_02889	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101441_02890	COG0765	amino acid transport
S101441_02891	COG0765	amino acid transport
S101441_02896	COG3881	PFAM PRC-barrel domain
S101441_02897	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
S101441_02898	COG0457	Tetratricopeptide repeat
S101441_02899	COG0482	sulfurtransferase activity
S101441_02900	COG1104	cysteine desulfurase activity
S101441_02901	COG1959	2 iron, 2 sulfur cluster binding
S101441_02902	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
S101441_02903	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
S101441_02904	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
S101441_02905	COG0124	histidyl-tRNA synthetase
S101441_02907	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101441_02907	COG3103	Sh3 type 3 domain protein
S101441_02907	COG4991	sh3 domain protein
S101441_02908	COG1490	D-aminoacyl-tRNA deacylase activity
S101441_02909	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S101441_02910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101441_02911	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
S101441_02911	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
S101441_02912	COG5416	Lipopolysaccharide assembly protein A domain
S101441_02913	COG0490	domain, Protein
S101441_02914	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101441_02914	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101441_02916	COG2244	polysaccharide biosynthetic process
S101441_02917	COG2323	membrane
S101441_02919	COG1862	Preprotein translocase
S101441_02920	COG0343	queuine tRNA-ribosyltransferase activity
S101441_02921	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
S101441_02923	COG2255	four-way junction helicase activity
S101441_02924	COG0632	four-way junction helicase activity
S101441_02926	COG2814	Major facilitator Superfamily
S101441_02927	COG0673	inositol 2-dehydrogenase activity
S101441_02928	COG2112	serine threonine protein kinase
S101441_02932	COG1115	amino acid carrier protein
S101441_02933	COG0217	transcriptional regulatory protein
S101441_02935	COG1388	LysM domain
S101441_02936	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
S101441_02937	COG0157	Belongs to the NadC ModD family
S101441_02938	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
S101441_02939	COG1104	cysteine desulfurase activity
S101441_02940	COG1827	regulation of RNA biosynthetic process
S101441_02941	COG0077	Prephenate dehydratase
S101441_02942	COG4492	Belongs to the UPF0735 family
S101441_02943	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
S101441_02944	COG3290	protein histidine kinase activity
S101441_02945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
S101441_02946	COG2868	ribosomal protein
S101441_02947	COG0261	This protein binds to 23S rRNA in the presence of protein L20
S101441_02948	COG1994	Peptidase M50
S101441_02949	COG0739	heme binding
S101441_02950	COG2894	cell division
S101441_02951	COG0850	regulation of cytokinetic process
S101441_02952	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
S101441_02953	COG1792	Involved in formation and maintenance of cell shape
S101441_02954	COG1077	Cell shape determining protein MreB Mrl
S101441_02955	COG2003	Belongs to the UPF0758 family
S101441_02956	COG0424	maF-like protein
S101441_02958	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
S101441_02959	COG0285	dihydrofolate synthase activity
S101441_02960	COG0525	valine-tRNA ligase activity
S101441_02962	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101441_02963	COG1388	LysM domain
S101441_02964	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
S101441_02965	COG0113	porphobilinogen synthase activity
S101441_02966	COG1587	Uroporphyrinogen-III synthase
S101441_02967	COG0181	hydroxymethylbilane synthase activity
S101441_02968	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101441_02969	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
S101441_02971	COG0218	Necessary for normal cell division and for the maintenance of normal septation
S101441_02972	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
S101441_02973	COG1067	ATP-dependent peptidase activity
S101441_02973	COG0470	DNA polymerase III
S101441_02974	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
S101441_02975	COG0544	peptidyl-prolyl cis-trans isomerase activity
S101441_02976	COG0457	Tetratricopeptide repeat
S101441_02976	COG1477	protein flavinylation
S101441_02977	COG0066	3-isopropylmalate dehydratase activity
S101441_02978	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
S101441_02979	COG0473	3-isopropylmalate dehydrogenase activity
S101441_02980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S101441_02981	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
S101441_02982	COG0440	acetolactate synthase activity
S101441_02983	COG0028	Belongs to the TPP enzyme family
S101441_02985	COG0454	-acetyltransferase
S101441_02986	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
S101441_02988	COG2801	Transposase and inactivated derivatives
S101441_02993	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
S101441_02998	COG0622	Phosphoesterase
S101441_02999	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
S101441_03000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
S101441_03001	COG5401	PFAM Sporulation and spore germination
S101441_03002	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
S101441_03003	COG1846	Transcriptional regulator
S101441_03004	COG2197	response regulator
S101441_03005	COG0824	Thioesterase
S101441_03006	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
S101441_03007	COG1053	succinate dehydrogenase
S101441_03008	COG2009	succinate dehydrogenase
S101441_03009	COG1719	4-vinyl reductase, 4VR
S101441_03010	COG0527	aspartate kinase activity
S101441_03011	COG0322	excinuclease ABC activity
S101441_03012	COG3118	belongs to the thioredoxin family
S101441_03013	COG3534	alpha-L-arabinofuranosidase
S101441_03015	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
S101441_03016	COG2086	electron transfer activity
S101441_03017	COG1024	Enoyl-CoA hydratase
S101441_03018	COG1309	transcriptional regulator
S101441_03019	COG0318	PFAM AMP-dependent synthetase and ligase
S101441_03020	COG3766	membrane
S101441_03021	COG1193	negative regulation of DNA recombination
S101441_03022	COG1796	DNA polymerase
S101441_03022	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101441_03023	COG1286	toxin biosynthetic process
S101441_03024	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
S101441_03025	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
S101441_03026	COG0072	phenylalanine-tRNA ligase activity
S101441_03026	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101441_03027	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
S101441_03028	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101441_03030	COG3835	regulator
S101441_03031	COG0277	FAD linked oxidase domain protein
S101441_03032	COG0247	lactate metabolic process
S101441_03033	COG0346	lactoylglutathione lyase activity
S101441_03034	COG1966	Carbon starvation protein
S101441_03035	COG3534	alpha-L-arabinofuranosidase
S101441_03036	COG0395	ABC-type sugar transport system, permease component
S101441_03037	COG1175	transmembrane transport
S101441_03038	COG1653	transport
S101441_03039	COG0371	Dehydrogenase
S101441_03040	COG0647	UMP catabolic process
S101441_03041	COG0647	UMP catabolic process
S101441_03042	COG0235	Class ii aldolase
S101441_03043	COG1069	ribulokinase activity
S101441_03044	COG2160	L-arabinose isomerase activity
S101441_03045	COG3507	Belongs to the glycosyl hydrolase 43 family
S101441_03046	COG1363	Peptidase, m42
S101441_03048	COG3326	Membrane
S101441_03049	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
S101441_03050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
S101441_03051	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
S101441_03053	COG1346	cytolysis
S101441_03054	COG1380	Effector of murein hydrolase LrgA
S101441_03055	COG3279	Response regulator of the LytR AlgR family
S101441_03056	COG3275	phosphorelay sensor kinase activity
S101441_03058	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S101441_03061	COG0398	Pfam SNARE associated Golgi protein
S101441_03062	COG1484	DNA-dependent DNA replication
S101441_03063	COG3611	Membrane attachment protein
S101441_03064	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
S101441_03065	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
S101441_03066	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101441_03067	COG1733	regulation of RNA biosynthetic process
S101441_03068	COG2814	Major facilitator Superfamily
S101441_03069	COG0656	L-ascorbic acid biosynthetic process
S101441_03071	COG0237	dephospho-CoA kinase activity
S101441_03072	COG1971	Probably functions as a manganese efflux pump
S101441_03073	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
S101441_03074	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101441_03074	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101441_03075	COG5002	protein histidine kinase activity
S101441_03076	COG0745	RESPONSE REGULATOR receiver
S101441_03077	COG0039	L-malate dehydrogenase activity
S101441_03078	COG0538	isocitrate dehydrogenase activity
S101441_03079	COG0372	Belongs to the citrate synthase family
S101441_03081	COG2707	UPF0756 membrane protein
S101441_03082	COG0628	permease
S101441_03083	COG3030	protein affecting phage T7 exclusion by the F plasmid
S101441_03084	COG0469	pyruvate kinase activity
S101441_03085	COG0205	6-phosphofructokinase activity
S101441_03086	COG0825	malonyl-CoA metabolic process
S101441_03087	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
S101441_03088	COG0281	malic enzyme
S101441_03089	COG0587	DNA-directed DNA polymerase activity
S101441_03093	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
S101441_03095	COG4109	DRTGG domain
S101441_03096	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
S101441_03097	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03099	COG0165	Argininosuccinate lyase
S101441_03100	COG0137	argininosuccinate synthase activity
S101441_03101	COG0521	Mo-molybdopterin cofactor biosynthetic process
S101441_03102	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
S101441_03103	COG0827	DNA restriction-modification system
S101441_03104	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
S101441_03105	COG3874	Sporulation protein YtfJ
S101441_03107	COG1714	RDD family
S101441_03108	COG0616	signal peptide processing
S101441_03109	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101441_03112	COG1574	metal-dependent hydrolase with the TIM-barrel fold
S101441_03113	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101441_03115	COG0301	tRNA thio-modification
S101441_03116	COG1104	cysteine desulfurase activity
S101441_03117	COG1114	Component of the transport system for branched-chain amino acids
S101441_03118	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
S101441_03119	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101441_03120	COG1309	transcriptional regulator
S101441_03121	COG1956	GAF domain-containing protein
S101441_03122	COG2203	Gaf domain
S101441_03122	COG2199	diguanylate cyclase activity
S101441_03123	COG2199	diguanylate cyclase activity
S101441_03123	COG2203	Gaf domain
S101441_03124	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
S101441_03126	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
S101441_03127	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101441_03128	COG0454	-acetyltransferase
S101441_03129	COG0517	IMP dehydrogenase activity
S101441_03130	COG0123	including yeast histone deacetylase and acetoin utilization protein
S101441_03131	COG1360	Flagellar Motor Protein
S101441_03132	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101441_03133	COG1609	Transcriptional regulator
S101441_03134	COG1605	Chorismate mutase
S101441_03134	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
S101441_03135	COG3118	belongs to the thioredoxin family
S101441_03136	COG4980	gas vesicle protein
S101441_03137	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101441_03138	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
S101441_03139	COG1674	ftsk spoiiie
S101441_03140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101441_03141	COG4848	Belongs to the UPF0354 family
S101441_03142	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_03145	COG1363	Peptidase, m42
S101441_03146	COG5584	Small secreted protein
S101441_03147	COG0281	malic enzyme
S101441_03148	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101441_03149	COG0220	tRNA (guanine-N7-)-methyltransferase activity
S101441_03151	COG0510	thiamine kinase activity
S101441_03152	COG1523	belongs to the glycosyl hydrolase 13 family
S101441_03153	COG1597	lipid kinase activity
S101441_03155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S101441_03156	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101441_03157	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101441_03158	COG2252	PERMEase
S101441_03159	COG4473	ABC transporter
S101441_03160	COG1131	(ABC) transporter
S101441_03161	COG1349	DNA-binding transcription factor activity
S101441_03162	COG1187	pseudouridine synthase activity
S101441_03163	COG2244	polysaccharide biosynthetic process
S101441_03164	COG2081	HI0933 family
S101441_03165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
S101441_03168	COG0673	inositol 2-dehydrogenase activity
S101441_03169	COG1653	transport
S101441_03170	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
S101441_03171	COG4209	transmembrane transport
S101441_03172	COG2207	Transcriptional regulator
S101441_03173	COG2207	Transcriptional regulator
S101441_03174	COG2207	Transcriptional regulator
S101441_03175	COG1653	transport
S101441_03176	COG0395	ABC-type sugar transport system, permease component
S101441_03177	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101441_03178	COG2124	cytochrome p450
S101441_03179	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
S101441_03181	COG0156	8-amino-7-oxononanoate synthase activity
S101441_03182	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101441_03183	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
S101441_03184	COG1073	alpha beta
S101441_03189	COG1486	melibiose metabolic process
S101441_03190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101441_03191	COG0495	leucyl-tRNA aminoacylation
S101441_03193	COG2202	Pas domain
S101441_03193	COG1366	Belongs to the anti-sigma-factor antagonist family
S101441_03194	COG2814	Major facilitator Superfamily
S101441_03195	COG2433	Pfam Transposase IS66
S101441_03196	COG0577	efflux transmembrane transporter activity
S101441_03197	COG1136	(ABC) transporter
S101441_03198	COG2205	protein histidine kinase activity
S101441_03199	COG0745	RESPONSE REGULATOR receiver
S101441_03200	COG0577	efflux transmembrane transporter activity
S101441_03201	COG1136	(ABC) transporter
S101441_03204	COG1131	(ABC) transporter
S101441_03205	COG1725	Transcriptional regulator
S101441_03208	COG1242	4 iron, 4 sulfur cluster binding
S101441_03209	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
S101441_03211	COG2267	carboxylic ester hydrolase activity
S101441_03212	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
S101441_03213	COG1113	amino acid transport
S101441_03214	COG0367	asparagine synthase
S101441_03215	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
S101441_03216	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
S101441_03218	COG1506	peptidase
S101441_03219	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101441_03220	COG1116	anion transmembrane transporter activity
S101441_03221	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101441_03222	COG0494	nUDIX hydrolase
S101441_03223	COG4824	toxin secretion phage lysis holin
S101441_03224	COG0783	Belongs to the Dps family
S101441_03227	COG1854	S-ribosylhomocysteine lyase activity
S101441_03228	COG0288	reversible hydration of carbon dioxide
S101441_03229	COG0254	rRNA binding
S101441_03230	COG1271	oxidase subunit
S101441_03231	COG1294	oxidase, subunit
S101441_03233	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101441_03234	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101441_03234	COG1321	iron dependent repressor
S101441_03235	COG1121	(ABC) transporter
S101441_03236	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101441_03237	COG4948	Mandelate Racemase Muconate Lactonizing
S101441_03238	COG0318	PFAM AMP-dependent synthetase and ligase
S101441_03239	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
S101441_03240	COG0596	Alpha beta hydrolase
S101441_03241	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
S101441_03242	COG1169	isochorismate synthase
S101441_03243	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101441_03244	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101441_03245	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101441_03246	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101441_03247	COG0438	transferase activity, transferring glycosyl groups
S101441_03249	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101441_03250	COG0438	transferase activity, transferring glycosyl groups
S101441_03251	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101441_03252	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
S101441_03253	COG0058	SHG alpha-glucan phosphorylase activity
S101441_03254	COG0297	glycogen (starch) synthase activity
S101441_03255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
S101441_03256	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
S101441_03257	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
S101441_03282	COG3859	Proton-coupled thiamine transporter YuaJ
S101441_03283	COG1247	-acetyltransferase
S101441_03284	COG2268	Band 7 protein
S101441_03285	COG1585	Membrane protein implicated in regulation of membrane protease activity
S101441_03286	COG2318	DinB family
S101441_03289	COG1454	alcohol dehydrogenase
S101441_03291	COG1510	regulation of RNA biosynthetic process
S101441_03293	COG0569	domain protein
S101441_03294	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S101441_03295	COG4682	membrane
S101441_03296	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101441_03297	COG0477	Major facilitator Superfamily
S101441_03298	COG5553	Cysteine dioxygenase type I
S101441_03300	COG1968	undecaprenyl-diphosphatase activity
S101441_03301	COG0628	permease
S101441_03302	COG0673	inositol 2-dehydrogenase activity
S101441_03303	COG4806	L-rhamnose isomerase
S101441_03304	COG3254	rhamnose metabolic process
S101441_03305	COG1070	Carbohydrate kinase
S101441_03306	COG1349	DNA-binding transcription factor activity
S101441_03307	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03307	COG3347	Dehydrogenase
S101441_03308	COG3347	Dehydrogenase
S101441_03308	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03309	COG0840	transmembrane signaling receptor activity
S101441_03310	COG0840	transmembrane signaling receptor activity
S101441_03311	COG0840	transmembrane signaling receptor activity
S101441_03312	COG0840	transmembrane signaling receptor activity
S101441_03313	COG0840	transmembrane signaling receptor activity
S101441_03316	COG0366	Alpha amylase catalytic
S101441_03317	COG1253	flavin adenine dinucleotide binding
S101441_03318	COG2738	Putative neutral zinc metallopeptidase
S101441_03321	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
S101441_03324	COG0166	Belongs to the GPI family
S101441_03325	COG1979	alcohol dehydrogenase
S101441_03326	COG1979	alcohol dehydrogenase
S101441_03327	COG2155	Conserved Protein
S101441_03328	COG1098	S1 RNA binding domain
S101441_03329	COG0436	Aminotransferase
S101441_03330	COG1522	sequence-specific DNA binding
S101441_03331	COG2267	carboxylic ester hydrolase activity
S101441_03333	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S101441_03334	COG2205	protein histidine kinase activity
S101441_03336	COG5018	Exonuclease
S101441_03338	COG2814	Major facilitator Superfamily
S101441_03339	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101441_03340	COG3011	Protein conserved in bacteria
S101441_03342	COG3290	protein histidine kinase activity
S101441_03343	COG4565	transcriptional regulatory protein
S101441_03348	COG3493	citrate carrier protein
S101441_03350	COG2111	Na H antiporter
S101441_03350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S101441_03351	COG2111	Na H antiporter
S101441_03352	COG1006	Multisubunit Na H antiporter MnhC subunit
S101441_03353	COG0651	ATP synthesis coupled electron transport
S101441_03354	COG1863	multisubunit Na H antiporter MnhE subunit
S101441_03355	COG2212	antiporter activity
S101441_03356	COG1320	monovalent cation:proton antiporter activity
S101441_03357	COG2050	protein possibly involved in aromatic compounds catabolism
S101441_03358	COG2197	response regulator
S101441_03359	COG4585	Histidine kinase
S101441_03361	COG0142	geranyltranstransferase activity
S101441_03365	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
S101441_03366	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
S101441_03367	COG1335	isochorismatase
S101441_03368	COG5506	Protein of unknown function (DUF1694)
S101441_03371	COG0628	permease
S101441_03374	COG1418	mRNA catabolic process
S101441_03375	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03377	COG1511	domain protein
S101441_03378	COG0433	COG0433 Predicted ATPase
S101441_03378	COG1674	ftsk spoiiie
S101441_03379	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101441_03380	COG5417	Belongs to the EsaB family
S101441_03381	COG4842	Belongs to the WXG100 family
S101441_03382	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S101441_03382	COG2508	Transcriptional regulator
S101441_03383	COG0686	Belongs to the AlaDH PNT family
S101441_03384	COG5634	Uncharacterized conserved protein (DUF2278)
S101441_03385	COG3251	PFAM MbtH domain protein
S101441_03386	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_03387	COG3433	isochorismatase activity
S101441_03387	COG1535	isochorismatase
S101441_03388	COG1021	2,3-dihydroxybenzoate-AMP ligase
S101441_03389	COG1169	isochorismate synthase
S101441_03390	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03391	COG2819	hydrolase of the alpha beta superfamily
S101441_03392	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101441_03393	COG1268	BioY protein
S101441_03394	COG2056	Na+-H+ antiporter family
S101441_03395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
S101441_03396	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
S101441_03397	COG3584	3D domain protein
S101441_03399	COG1252	NADH dehydrogenase
S101441_03400	COG0492	ferredoxin-NADP+ reductase activity
S101441_03402	COG0516	GMP reductase activity
S101441_03403	COG2808	Putative FMN-binding domain
S101441_03404	COG0316	Belongs to the HesB IscA family
S101441_03405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
S101441_03406	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101441_03409	COG4844	belongs to the
S101441_03410	COG1252	NADH dehydrogenase
S101441_03411	COG4837	Protein of unknown function (DUF1462)
S101441_03412	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
S101441_03413	COG1506	peptidase
S101441_03413	COG4946	Tricorn protease homolog
S101441_03413	COG0823	Involved in the tonB-independent uptake of proteins
S101441_03414	COG0083	homoserine kinase activity
S101441_03415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
S101441_03416	COG0460	homoserine dehydrogenase
S101441_03417	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101441_03418	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S101441_03419	COG0647	UMP catabolic process
S101441_03420	COG2445	Protein of unknown function DUF86
S101441_03421	COG4470	Protein conserved in bacteria
S101441_03423	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
S101441_03424	COG0739	heme binding
S101441_03426	COG3377	Domain of unknown function (DUF1805)
S101441_03427	COG0737	Belongs to the 5'-nucleotidase family
S101441_03428	COG0730	response to heat
S101441_03429	COG1801	Protein of unknown function DUF72
S101441_03431	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S101441_03432	COG2508	Transcriptional regulator
S101441_03433	COG2233	PERMEase
S101441_03434	COG2233	PERMEase
S101441_03435	COG3648	Uricase
S101441_03435	COG3195	allantoin biosynthetic process
S101441_03436	COG2351	hydroxyisourate hydrolase activity
S101441_03439	COG2080	2 iron, 2 sulfur cluster binding
S101441_03440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
S101441_03441	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
S101441_03442	COG2068	MobA-Related Protein
S101441_03443	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
S101441_03444	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
S101441_03445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101441_03446	COG2356	endonuclease I
S101441_03447	COG3842	ATPase activity
S101441_03448	COG2188	Transcriptional regulator
S101441_03449	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101441_03450	COG0395	ABC-type sugar transport system, permease component
S101441_03451	COG0395	ABC-type sugar transport system, permease component
S101441_03452	COG1175	transmembrane transport
S101441_03453	COG1653	transport
S101441_03454	COG2222	sugar isomerase
S101441_03455	COG0322	excinuclease ABC activity
S101441_03456	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101441_03459	COG2801	Transposase and inactivated derivatives
S101441_03461	COG0346	lactoylglutathione lyase activity
S101441_03462	COG0640	Transcriptional regulator
S101441_03465	COG5444	nuclease activity
S101441_03467	COG3409	Peptidoglycan-binding domain 1 protein
S101441_03467	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101441_03468	COG4824	toxin secretion phage lysis holin
S101441_03475	COG3953	SLT domain
S101441_03475	COG5412	phage tail tape measure protein
S101441_03495	COG0582	viral genome integration into host DNA
S101441_03517	COG3800	Transcriptional regulator
S101441_03517	COG1396	sequence-specific DNA binding
S101441_03522	COG0719	Fe-S assembly protein
S101441_03523	COG0822	iron-sulfur transferase activity
S101441_03524	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101441_03525	COG0719	Fe-S assembly protein
S101441_03526	COG0396	ATPase activity
S101441_03527	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S101441_03528	COG1464	Belongs to the NlpA lipoprotein family
S101441_03529	COG2011	ABC-type metal ion transport system permease component
S101441_03530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
S101441_03532	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101441_03533	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101441_03535	COG0509	glycine decarboxylation via glycine cleavage system
S101441_03536	COG1393	Belongs to the ArsC family
S101441_03537	COG1960	acyl-CoA dehydrogenase activity
S101441_03538	COG0183	Belongs to the thiolase family
S101441_03539	COG1024	Enoyl-CoA hydratase
S101441_03539	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101441_03541	COG0506	proline dehydrogenase activity
S101441_03543	COG5577	PFAM Coat F domain
S101441_03544	COG1846	Transcriptional regulator
S101441_03545	COG0477	Major facilitator Superfamily
S101441_03546	COG1942	4-Oxalocrotonate Tautomerase
S101441_03547	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03548	COG0583	DNA-binding transcription factor activity
S101441_03550	COG1120	ATPase activity
S101441_03555	COG1131	(ABC) transporter
S101441_03563	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03564	COG0783	Belongs to the Dps family
S101441_03567	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101441_03568	COG0745	RESPONSE REGULATOR receiver
S101441_03569	COG2205	protein histidine kinase activity
S101441_03569	COG2770	Histidine kinase
S101441_03570	COG1309	transcriptional regulator
S101441_03571	COG0114	fumarate hydratase activity
S101441_03573	COG0697	spore germination
S101441_03574	COG0814	amino acid
S101441_03576	COG2197	response regulator
S101441_03577	COG4585	Histidine kinase
S101441_03578	COG4758	membrane
S101441_03579	COG3595	metallopeptidase activity
S101441_03580	COG1842	Phage shock protein A
S101441_03581	COG4758	membrane
S101441_03582	COG2814	Major facilitator Superfamily
S101441_03583	COG2096	Adenosyltransferase
S101441_03584	COG1120	ATPase activity
S101441_03585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_03586	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101441_03587	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03588	COG3386	PFAM SMP-30 Gluconolaconase
S101441_03589	COG2205	protein histidine kinase activity
S101441_03590	COG0745	RESPONSE REGULATOR receiver
S101441_03592	COG1191	sigma factor activity
S101441_03594	COG2140	Oxalate decarboxylase
S101441_03596	COG0577	efflux transmembrane transporter activity
S101441_03597	COG1136	(ABC) transporter
S101441_03598	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S101441_03599	COG1120	ATPase activity
S101441_03600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_03601	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101441_03602	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101441_03604	COG0531	amino acid
S101441_03606	COG1988	membrane-bound metal-dependent
S101441_03607	COG1368	sulfuric ester hydrolase activity
S101441_03608	COG1910	domain protein
S101441_03609	COG0725	ABC transporter, periplasmic molybdate-binding protein
S101441_03610	COG4149	molybdate abc transporter
S101441_03611	COG0656	L-ascorbic acid biosynthetic process
S101441_03613	COG0025	NhaP-type Na H and K H
S101441_03614	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101441_03615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101441_03616	COG3973	AAA domain
S101441_03618	COG2860	membrane
S101441_03619	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
S101441_03620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S101441_03621	COG2217	Heavy metal translocating P-type atpase
S101441_03624	COG2217	Heavy metal translocating P-type atpase
S101441_03625	COG2608	mercury ion transmembrane transporter activity
S101441_03626	COG1937	Protein conserved in bacteria
S101441_03627	COG0673	inositol 2-dehydrogenase activity
S101441_03628	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101441_03629	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101441_03630	COG1289	transmembrane transporter activity
S101441_03632	COG2076	Multidrug Resistance protein
S101441_03633	COG1309	transcriptional regulator
S101441_03634	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_03637	COG5444	nuclease activity
S101441_03640	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101441_03640	COG3409	Peptidoglycan-binding domain 1 protein
S101441_03641	COG4824	toxin secretion phage lysis holin
S101441_03646	COG3942	CHAP domain
S101441_03646	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101441_03669	COG0582	viral genome integration into host DNA
S101441_03693	COG0582	viral genome integration into host DNA
S101441_03694	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
S101441_03695	COG0557	exoribonuclease II activity
S101441_03696	COG1647	Serine aminopeptidase, S33
S101441_03697	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101441_03698	COG0596	Alpha beta hydrolase
S101441_03699	COG1476	TRANSCRIPTIONal
S101441_03700	COG1396	sequence-specific DNA binding
S101441_03701	COG1396	sequence-specific DNA binding
S101441_03702	COG1733	regulation of RNA biosynthetic process
S101441_03703	COG0840	transmembrane signaling receptor activity
S101441_03704	COG1174	glycine betaine transport
S101441_03705	COG1732	Glycine betaine
S101441_03706	COG1174	glycine betaine transport
S101441_03707	COG0517	IMP dehydrogenase activity
S101441_03707	COG1125	glycine betaine transport
S101441_03708	COG1510	regulation of RNA biosynthetic process
S101441_03709	COG1174	glycine betaine transport
S101441_03710	COG1732	Glycine betaine
S101441_03711	COG1174	glycine betaine transport
S101441_03712	COG0517	IMP dehydrogenase activity
S101441_03712	COG1125	glycine betaine transport
S101441_03713	COG1510	regulation of RNA biosynthetic process
S101441_03714	COG2095	MarC family integral membrane protein
S101441_03716	COG3064	Membrane
S101441_03717	COG4640	response to antibiotic
S101441_03718	COG0456	acetyltransferase
S101441_03719	COG0148	phosphopyruvate hydratase activity
S101441_03720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
S101441_03721	COG0149	triose-phosphate isomerase activity
S101441_03722	COG0126	phosphoglycerate kinase activity
S101441_03723	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101441_03724	COG2390	Transcriptional regulator
S101441_03725	COG2814	Major facilitator Superfamily
S101441_03726	COG1609	Transcriptional regulator
S101441_03727	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101441_03728	COG0583	DNA-binding transcription factor activity
S101441_03729	COG0697	spore germination
S101441_03730	COG1113	amino acid transport
S101441_03731	COG3858	chitin binding
S101441_03732	COG1556	Lactate utilization protein
S101441_03733	COG1139	Iron-sulfur cluster binding protein
S101441_03734	COG0247	lactate metabolic process
S101441_03737	COG2197	response regulator
S101441_03738	COG4585	Histidine kinase
S101441_03739	COG0842	Transport permease protein
S101441_03740	COG1131	(ABC) transporter
S101441_03741	COG0596	Alpha beta hydrolase
S101441_03742	COG2208	phosphoserine phosphatase activity
S101441_03743	COG3867	Arabinogalactan endo-beta-1,4-galactanase
S101441_03744	COG1874	Beta-galactosidase
S101441_03745	COG3833	ABC-type maltose transport systems, permease component
S101441_03746	COG1175	transmembrane transport
S101441_03747	COG2182	Extracellular solute-binding protein
S101441_03748	COG1609	Transcriptional regulator
S101441_03749	COG2186	Transcriptional regulator
S101441_03750	COG1620	l-lactate permease
S101441_03751	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S101441_03752	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S101441_03754	COG5039	Polysaccharide pyruvyl transferase
S101441_03755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101441_03756	COG0110	maltose O-acetyltransferase activity
S101441_03757	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
S101441_03758	COG2244	polysaccharide biosynthetic process
S101441_03759	COG1216	Glycosyl transferase, family 2
S101441_03760	COG5039	Polysaccharide pyruvyl transferase
S101441_03761	COG1216	Glycosyl transferase, family 2
S101441_03763	COG0438	transferase activity, transferring glycosyl groups
S101441_03764	COG1215	transferase activity, transferring glycosyl groups
S101441_03765	COG0438	transferase activity, transferring glycosyl groups
S101441_03766	COG1086	Polysaccharide biosynthesis protein
S101441_03767	COG0489	protein tyrosine kinase activity
S101441_03768	COG3944	biosynthesis protein
S101441_03769	COG1396	sequence-specific DNA binding
S101441_03770	COG2272	Belongs to the type-B carboxylesterase lipase family
S101441_03772	COG3479	Phenolic acid decarboxylase
S101441_03775	COG1794	racemase activity, acting on amino acids and derivatives
S101441_03776	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101441_03777	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101441_03778	COG1621	beta-fructofuranosidase activity
S101441_03779	COG1621	beta-fructofuranosidase activity
S101441_03780	COG0531	amino acid
S101441_03781	COG1309	transcriptional regulator
S101441_03782	COG2076	Multidrug Resistance protein
S101441_03783	COG2076	Multidrug Resistance protein
S101441_03786	COG0740	serine-type endopeptidase activity
S101441_03787	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101441_03788	COG0366	Alpha amylase catalytic
S101441_03789	COG1554	hydrolase, family 65, central catalytic
S101441_03790	COG5521	maltodextrose utilization protein MalA
S101441_03791	COG3833	ABC-type maltose transport systems, permease component
S101441_03792	COG1175	transmembrane transport
S101441_03793	COG2182	Extracellular solute-binding protein
S101441_03794	COG0366	Alpha amylase catalytic
S101441_03795	COG1609	Transcriptional regulator
S101441_03796	COG1611	Belongs to the LOG family
S101441_03797	COG1694	Mazg nucleotide pyrophosphohydrolase
S101441_03798	COG0659	secondary active sulfate transmembrane transporter activity
S101441_03799	COG0288	reversible hydration of carbon dioxide
S101441_03800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101441_03801	COG0577	efflux transmembrane transporter activity
S101441_03802	COG1136	(ABC) transporter
S101441_03803	COG5002	protein histidine kinase activity
S101441_03804	COG0745	RESPONSE REGULATOR receiver
S101441_03806	COG2162	N-hydroxyarylamine O-acetyltransferase activity
S101441_03807	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_03808	COG1481	regulation of sporulation
S101441_03809	COG0391	Required for morphogenesis under gluconeogenic growth conditions
S101441_03810	COG1660	Displays ATPase and GTPase activities
S101441_03811	COG1051	belongs to the nudix hydrolase family
S101441_03812	COG0492	ferredoxin-NADP+ reductase activity
S101441_03813	COG3883	PFAM NLP P60 protein
S101441_03813	COG0791	NLP P60 protein
S101441_03814	COG0457	Tetratricopeptide repeat
S101441_03815	COG1132	(ABC) transporter
S101441_03819	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
S101441_03819	COG0140	phosphoribosyl-ATP diphosphatase activity
S101441_03820	COG0107	imidazoleglycerol-phosphate synthase activity
S101441_03821	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
S101441_03822	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
S101441_03823	COG0131	Imidazoleglycerol-phosphate dehydratase
S101441_03824	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
S101441_03825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
S101441_03826	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
S101441_03827	COG4990	cell redox homeostasis
S101441_03828	COG5297	Belongs to the glycosyl hydrolase family 6
S101441_03830	COG2801	Transposase and inactivated derivatives
S101441_03831	COG0110	maltose O-acetyltransferase activity
S101441_03832	COG0546	phosphoglycolate phosphatase activity
S101441_03833	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
S101441_03834	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
S101441_03835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
S101441_03836	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
S101441_03837	COG0363	glucosamine-6-phosphate deaminase activity
S101441_03839	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
S101441_03842	COG1950	PFAM Membrane protein of
S101441_03843	COG1983	PspC domain protein
S101441_03844	COG3595	metallopeptidase activity
S101441_03847	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101441_03848	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
S101441_03849	COG0556	nucleotide-excision repair
S101441_03850	COG4897	Protein conserved in bacteria
S101441_03851	COG0574	Belongs to the PEP-utilizing enzyme family
S101441_03851	COG3848	Pyruvate phosphate dikinase
S101441_03852	COG1309	transcriptional regulator
S101441_03853	COG2814	Major facilitator Superfamily
S101441_03854	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101441_03856	COG3409	Peptidoglycan-binding domain 1 protein
S101441_03856	COG0793	Belongs to the peptidase S41A family
S101441_03857	COG2177	Part of the ABC transporter FtsEX involved in
S101441_03858	COG2884	Cell division ATP-binding protein ftsE
S101441_03859	COG2010	Cytochrome c
S101441_03860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101441_03861	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
S101441_03862	COG0653	protein targeting
S101441_03864	COG2801	Transposase and inactivated derivatives
S101441_03865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
S101441_03868	COG1516	flagellar protein fliS
S101441_03869	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
S101441_03870	COG1334	flagellar protein FlaG
S101441_03871	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101441_03872	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
S101441_03873	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
S101441_03876	COG0791	NLP P60 protein
S101441_03877	COG0561	phosphatase activity
S101441_03878	COG1316	TRANSCRIPTIONal
S101441_03879	COG2814	Major facilitator Superfamily
S101441_03881	COG0814	amino acid
S101441_03882	COG0697	spore germination
S101441_03883	COG1482	cell wall glycoprotein biosynthetic process
S101441_03884	COG4193	domain, Protein
S101441_03885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101441_03886	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
S101441_03887	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
S101441_03888	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101441_03889	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101441_03889	COG0463	Glycosyl transferase, family 2
S101441_03891	COG1682	transport, permease protein
S101441_03892	COG1134	teichoic acid transport
S101441_03894	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101441_03895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
S101441_03899	COG2244	polysaccharide biosynthetic process
S101441_03900	COG0438	transferase activity, transferring glycosyl groups
S101441_03900	COG0297	glycogen (starch) synthase activity
S101441_03901	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101441_03903	COG3307	-O-antigen
S101441_03904	COG3206	protein involved in exopolysaccharide biosynthesis
S101441_03905	COG1215	transferase activity, transferring glycosyl groups
S101441_03906	COG0438	transferase activity, transferring glycosyl groups
S101441_03907	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S101441_03909	COG1131	(ABC) transporter
S101441_03916	COG1316	TRANSCRIPTIONal
S101441_03917	COG1739	Uncharacterized protein family UPF0029
S101441_03918	COG4585	Histidine kinase
S101441_03919	COG2197	response regulator
S101441_03920	COG1307	EDD domain protein, DegV family
S101441_03921	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
S101441_03923	COG1040	competence protein
S101441_03925	COG2747	anti-sigma28 factor FlgM
S101441_03926	COG3418	PFAM FlgN family protein
S101441_03927	COG1256	bacterial-type flagellum assembly
S101441_03927	COG4786	Flagellar basal body rod
S101441_03928	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101441_03932	COG2843	Capsule synthesis protein
S101441_03934	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S101441_03936	COG1609	Transcriptional regulator
S101441_03937	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101441_03938	COG1869	D-ribose catabolic process
S101441_03939	COG1129	ABC transporter
S101441_03940	COG1172	Belongs to the binding-protein-dependent transport system permease family
S101441_03941	COG1879	ABC-type sugar transport system periplasmic component
S101441_03942	COG3103	Sh3 type 3 domain protein
S101441_03944	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101441_03945	COG3527	Alpha-acetolactate decarboxylase
S101441_03946	COG0028	Belongs to the TPP enzyme family
S101441_03947	COG0583	DNA-binding transcription factor activity
S101441_03948	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101441_03951	COG5337	Spore coat protein CotH
S101441_03953	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S101441_03955	COG0405	Gamma-glutamyltransferase
S101441_03956	COG1522	sequence-specific DNA binding
S101441_03957	COG2059	Chromate
S101441_03958	COG2059	Chromate
S101441_03960	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101441_03961	COG0583	DNA-binding transcription factor activity
S101441_03965	COG5444	nuclease activity
S101441_03968	COG5444	nuclease activity
S101441_03971	COG3878	Protein conserved in bacteria
S101441_03972	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101441_03973	COG4464	protein tyrosine phosphatase activity
S101441_03974	COG0489	protein tyrosine kinase activity
S101441_03975	COG3944	biosynthesis protein
S101441_03977	COG4715	Zinc finger, swim domain protein
S101441_03978	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101441_03979	COG0561	phosphatase activity
S101441_03980	COG1349	DNA-binding transcription factor activity
S101441_03981	COG0629	single-stranded DNA binding
S101441_03984	COG3764	Sortase (surface protein transpeptidase)
S101441_03985	COG2972	Histidine kinase
S101441_03985	COG0745	RESPONSE REGULATOR receiver
S101441_03986	COG1970	mechanosensitive ion channel activity
S101441_03987	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S101441_03988	COG0457	Tetratricopeptide repeat
S101441_03989	COG4786	Flagellar basal body rod
S101441_03990	COG4786	Flagellar basal body rod
S101441_03991	COG1077	Cell shape determining protein MreB Mrl
S101441_03992	COG1609	Transcriptional regulator
S101441_03993	COG1846	Transcriptional regulator
S101441_03994	COG2814	Major facilitator Superfamily
S101441_03995	COG3420	alginic acid biosynthetic process
S101441_03996	COG1953	Uracil, thiamine, allantoin
S101441_03997	COG0477	Major facilitator Superfamily
S101441_03998	COG1335	isochorismatase
S101441_04000	COG0004	ammonium transporteR
S101441_04001	COG0347	Belongs to the P(II) protein family
S101441_04002	COG0671	phosphoesterase, PA-phosphatase related
S101441_04004	COG0739	heme binding
S101441_04005	COG1247	-acetyltransferase
S101441_04007	COG2089	acid synthase
S101441_04009	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101441_04010	COG0789	Transcriptional regulator
S101441_04012	COG2910	NAD(P)H-binding
S101441_04013	COG2910	NAD(P)H-binding
S101441_04014	COG1959	2 iron, 2 sulfur cluster binding
S101441_04015	COG0804	urea catabolic process
S101441_04016	COG0832	Belongs to the urease beta subunit family
S101441_04017	COG0831	urea catabolic process
S101441_04019	COG3237	CsbD-like
S101441_04020	COG1994	Peptidase M50
S101441_04021	COG0457	Tetratricopeptide repeat
S101441_04022	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
S101441_04023	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
S101441_04025	COG2304	oxidoreductase activity
S101441_04026	COG2304	oxidoreductase activity
S101441_04027	COG2385	sporulation resulting in formation of a cellular spore
S101441_04028	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101441_04030	COG4836	Membrane
S101441_04032	COG0355	proton-transporting ATP synthase activity, rotational mechanism
S101441_04033	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
S101441_04034	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
S101441_04035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
S101441_04036	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
S101441_04037	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
S101441_04038	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
S101441_04039	COG0356	it plays a direct role in the translocation of protons across the membrane
S101441_04041	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
S101441_04042	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
S101441_04043	COG4475	Protein of unknown function (DUF436)
S101441_04044	COG0698	ribose 5-phosphate isomerase
S101441_04045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101441_04046	COG1971	Probably functions as a manganese efflux pump
S101441_04047	COG0009	L-threonylcarbamoyladenylate synthase
S101441_04048	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
S101441_04052	COG2890	protein-(glutamine-N5) methyltransferase activity
S101441_04053	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
S101441_04054	COG0346	lactoylglutathione lyase activity
S101441_04055	COG0789	Transcriptional regulator
S101441_04056	COG0679	Auxin Efflux Carrier
S101441_04057	COG0281	malic enzyme
S101441_04058	COG1435	thymidine kinase activity
S101441_04059	COG0254	rRNA binding
S101441_04060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
S101441_04061	COG1494	fructose-1,6-bisphosphatase
S101441_04062	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101441_04064	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
S101441_04065	COG0191	fructose-bisphosphate aldolase activity
S101441_04066	COG2204	response regulator
S101441_04068	COG4821	SIS domain
S101441_04069	COG2801	Transposase and inactivated derivatives
S101441_04071	COG0504	CTP synthase activity
S101441_04072	COG3343	RNA polymerase activity
S101441_04073	COG1960	acyl-CoA dehydrogenase activity
S101441_04074	COG0247	lactate metabolic process
S101441_04074	COG2181	nitrate reductase activity
S101441_04075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101441_04076	COG4294	response to UV
S101441_04081	COG0018	arginyl-trna synthetase
S101441_04082	COG4506	Protein conserved in bacteria
S101441_04084	COG0535	radical SAM domain protein
S101441_04086	COG1131	(ABC) transporter
S101441_04087	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S101441_04088	COG0612	Peptidase, M16
S101441_04089	COG0612	Peptidase, M16
S101441_04091	COG3391	amine dehydrogenase activity
S101441_04092	COG3391	amine dehydrogenase activity
S101441_04093	COG3391	amine dehydrogenase activity
S101441_04094	COG0457	Tetratricopeptide repeat
S101441_04096	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S101441_04097	COG0010	Belongs to the arginase family
S101441_04098	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
S101441_04099	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101441_04102	COG1994	Peptidase M50
S101441_04103	COG1942	4-Oxalocrotonate Tautomerase
S101441_04104	COG1846	Transcriptional regulator
S101441_04105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S101441_04107	COG0477	Major facilitator Superfamily
S101441_04108	COG1959	2 iron, 2 sulfur cluster binding
S101441_04109	COG3465	dGTPase activity
S101441_04110	COG1078	dGTPase activity
S101441_04111	COG4844	belongs to the
S101441_04113	COG0697	spore germination
S101441_04114	COG0095	Lipoate-protein ligase
S101441_04115	COG0583	DNA-binding transcription factor activity
S101441_04116	COG0280	phosphate acetyltransferase
S101441_04118	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_04119	COG0436	Aminotransferase
S101441_04120	COG2814	Major facilitator Superfamily
S101441_04121	COG0151	Belongs to the GarS family
S101441_04122	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_04123	COG1917	Cupin 2, conserved barrel domain protein
S101441_04124	COG0077	Prephenate dehydratase
S101441_04127	COG2814	Major facilitator Superfamily
S101441_04128	COG0833	amino acid
S101441_04129	COG4187	Peptidase family M20/M25/M40
S101441_04130	COG1012	belongs to the aldehyde dehydrogenase family
S101441_04131	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101441_04133	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
S101441_04134	COG1091	dTDP-4-dehydrorhamnose reductase activity
S101441_04135	COG1088	dTDP-glucose 4,6-dehydratase activity
S101441_04136	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
S101441_04137	COG3980	spore coat polysaccharide biosynthesis protein
S101441_04138	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
S101441_04139	COG2089	acid synthase
S101441_04140	COG0456	acetyltransferase
S101441_04141	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101441_04142	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101441_04143	COG0463	Glycosyl transferase, family 2
S101441_04146	COG2363	Small membrane protein
S101441_04147	COG2233	PERMEase
S101441_04149	COG1012	belongs to the aldehyde dehydrogenase family
S101441_04150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
S101441_04151	COG1216	Glycosyl transferase, family 2
S101441_04152	COG0351	phosphomethylpyrimidine kinase
S101441_04154	COG1621	beta-fructofuranosidase activity
S101441_04155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_04155	COG1263	PTS System
S101441_04156	COG2116	formate transmembrane transporter activity
S101441_04157	COG3711	transcriptional antiterminator
S101441_04159	COG1404	Belongs to the peptidase S8 family
S101441_04160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101441_04161	COG0778	Nitroreductase
S101441_04162	COG0772	Belongs to the SEDS family
S101441_04165	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S101441_04166	COG1845	cytochrome c oxidase, subunit III
S101441_04167	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101441_04168	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101441_04169	COG2261	transglycosylase associated protein
S101441_04170	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
S101441_04171	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
S101441_04172	COG2246	polysaccharide biosynthetic process
S101441_04173	COG1309	transcriptional regulator
S101441_04175	COG3162	membrane
S101441_04176	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101441_04177	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S101441_04178	COG2837	iron assimilation
S101441_04179	COG2822	iron ion transport
S101441_04180	COG0672	)-iron permease
S101441_04181	COG0352	thiamine-phosphate diphosphorylase activity
S101441_04182	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
S101441_04183	COG0583	DNA-binding transcription factor activity
S101441_04184	COG1380	Effector of murein hydrolase LrgA
S101441_04185	COG1346	cytolysis
S101441_04186	COG2814	Major facilitator Superfamily
S101441_04187	COG4895	conserved protein (DUF2196)
S101441_04188	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
S101441_04189	COG0346	lactoylglutathione lyase activity
S101441_04193	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101441_04194	COG1404	Belongs to the peptidase S8 family
S101441_04195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_04195	COG1263	PTS System
S101441_04196	COG3711	transcriptional antiterminator
S101441_04198	COG1442	glycosyl transferase family 8
S101441_04199	COG5522	Integral membrane protein (intg_mem_TP0381)
S101441_04200	COG1846	Transcriptional regulator
S101441_04201	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
S101441_04202	COG2234	aminopeptidase activity
S101441_04203	COG2357	RelA SpoT domain protein
S101441_04205	COG2801	Transposase and inactivated derivatives
S101441_04206	COG1575	Belongs to the MenA family. Type 1 subfamily
S101441_04208	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101441_04209	COG1696	Membrane protein involved in D-alanine export
S101441_04210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101441_04211	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
S101441_04212	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S101441_04213	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S101441_04214	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S101441_04215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101441_04216	COG1486	melibiose metabolic process
S101441_04217	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101441_04218	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101441_04219	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101441_04220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101441_04220	COG3711	transcriptional antiterminator
S101441_04222	COG2094	Belongs to the DNA glycosylase MPG family
S101441_04223	COG0753	catalase activity
S101441_04224	COG2814	Major facilitator Superfamily
S101441_04225	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101441_04226	COG1131	(ABC) transporter
S101441_04230	COG1595	DNA-templated transcription, initiation
S101441_04231	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101441_04232	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
S101441_04233	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
S101441_04234	COG4988	ABC transporter
S101441_04235	COG1294	oxidase, subunit
S101441_04236	COG1271	oxidase subunit
S101441_04237	COG3493	citrate carrier protein
S101441_04238	COG0501	Belongs to the peptidase M48B family
S101441_04240	COG0726	polysaccharide deacetylase
S101441_04241	COG3842	ATPase activity
S101441_04242	COG2508	Transcriptional regulator
S101441_04243	COG1012	belongs to the aldehyde dehydrogenase family
S101441_04244	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101441_04247	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S101441_04249	COG4585	Histidine kinase
S101441_04250	COG4585	Histidine kinase
S101441_04251	COG2197	response regulator
S101441_04252	COG2195	Cleaves the N-terminal amino acid of tripeptides
S101441_04254	COG4894	glucomannan catabolic process
S101441_04255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101441_04256	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101441_04257	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_04258	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101441_04259	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101441_04260	COG2610	gluconate transmembrane transporter activity
S101441_04261	COG0500	methyltransferase
S101441_04262	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101441_04265	COG0753	catalase activity
S101441_04265	COG0693	protein deglycase activity
S101441_04266	COG2851	Citrate transporter
S101441_04267	COG2273	Hydrolase Family 16
S101441_04268	COG3711	transcriptional antiterminator
S101441_04270	COG2270	Major facilitator Superfamily
S101441_04271	COG0513	Belongs to the DEAD box helicase family
S101441_04272	COG2755	lipolytic protein G-D-S-L family
S101441_04272	COG3401	FG-GAP repeat protein
S101441_04295	COG0697	spore germination
S101441_04298	COG0589	response to stress
S101441_04299	COG2723	6-phospho-beta-galactosidase activity
S101441_04302	COG5444	nuclease activity
S101441_04306	COG0494	nUDIX hydrolase
S101441_04307	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
S101441_04308	COG3507	Belongs to the glycosyl hydrolase 43 family
S101441_04309	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
S101441_04310	COG0833	amino acid
S101441_04311	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
S101441_04312	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101441_04313	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
S101441_04314	COG2390	Transcriptional regulator
S101441_04316	COG3192	ethanolamine utilization protein
S101441_04317	COG2079	MmgE PrpD family protein
S101441_04319	COG1126	abc transporter atp-binding protein
S101441_04320	COG0765	amino acid transport
S101441_04321	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101441_04324	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
S101441_04325	COG0561	phosphatase activity
S101441_04331	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101441_04332	COG5294	Protein conserved in bacteria
S101441_04333	COG0577	efflux transmembrane transporter activity
S101441_04334	COG1136	(ABC) transporter
S101441_04335	COG2205	protein histidine kinase activity
S101441_04336	COG0745	RESPONSE REGULATOR receiver
S101441_04337	COG0191	fructose-bisphosphate aldolase activity
S101441_04338	COG1082	Xylose isomerase domain protein TIM barrel
S101441_04339	COG1082	Xylose isomerase domain protein TIM barrel
S101441_04340	COG0673	inositol 2-dehydrogenase activity
S101441_04341	COG2814	Major facilitator Superfamily
S101441_04342	COG1082	Xylose isomerase domain protein TIM barrel
S101441_04343	COG3962	Belongs to the TPP enzyme family
S101441_04344	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101441_04347	COG1349	DNA-binding transcription factor activity
S101441_04348	COG0667	Aldo Keto reductase
S101441_04354	COG2814	Major facilitator Superfamily
S101441_04355	COG2814	Major facilitator Superfamily
S101441_04356	COG0326	Molecular chaperone. Has ATPase activity
S101441_04358	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_04359	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_04360	COG1309	transcriptional regulator
S101441_04361	COG1012	belongs to the aldehyde dehydrogenase family
S101441_04362	COG1714	RDD family
S101441_04364	COG1714	RDD family
S101441_04365	COG2311	Membrane
S101441_04366	COG1917	Cupin 2, conserved barrel domain protein
S101441_04367	COG1309	transcriptional regulator
S101441_04368	COG1028	Short-chain dehydrogenase reductase Sdr
S101441_04369	COG1846	Transcriptional regulator
S101441_04370	COG1380	Effector of murein hydrolase LrgA
S101441_04371	COG1346	cytolysis
S101441_04372	COG5039	Polysaccharide pyruvyl transferase
S101441_04373	COG1929	Belongs to the glycerate kinase type-1 family
S101441_04374	COG1802	Transcriptional regulator
S101441_04375	COG1070	Carbohydrate kinase
S101441_04376	COG2610	gluconate transmembrane transporter activity
S101441_04377	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S101441_04378	COG0450	alkyl hydroperoxide reductase
S101441_04379	COG3634	alkyl hydroperoxide reductase activity
S101441_04380	COG2723	6-phospho-beta-galactosidase activity
S101441_04381	COG2190	(PTS) system
S101441_04381	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101441_04381	COG1263	PTS System
S101441_04382	COG2188	Transcriptional regulator
S101441_04384	COG1131	(ABC) transporter
S101441_04385	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
S101441_04387	COG0071	Belongs to the small heat shock protein (HSP20) family
S101441_04388	COG3773	Cell wall hydrolase
S101441_04393	COG0210	DNA helicase
S101441_04396	COG2963	transposase activity
S101441_04404	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
S101441_04407	COG1063	alcohol dehydrogenase
S101441_04411	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
S101441_04412	COG0456	acetyltransferase
S101441_04413	COG0457	Tetratricopeptide repeat
S101441_04414	COG0457	Tetratricopeptide repeat
S101441_04416	COG0010	Belongs to the arginase family
S101441_04417	COG0833	amino acid
S101441_04418	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101441_04422	COG5658	integral membrane protein
S101441_04423	COG0640	Transcriptional regulator
S101441_04424	COG3829	transcription factor binding
S101441_04425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101441_04426	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
S101441_04427	COG4853	Protein conserved in bacteria
S101441_04428	COG4863	YycH protein
S101441_04429	COG5002	protein histidine kinase activity
S101441_04430	COG0745	RESPONSE REGULATOR receiver
S101441_04436	COG0346	lactoylglutathione lyase activity
S101441_04437	COG0305	Participates in initiation and elongation during chromosome replication
S101441_04440	COG3093	addiction module antidote protein HigA
S101441_04441	COG2807	transmembrane transport
S101441_04442	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101441_04443	COG0359	binds to the 23S rRNA
S101441_04444	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
S101441_04445	COG4241	membrane
S101441_04446	COG4241	membrane
S101441_04448	COG5577	PFAM Coat F domain
S101441_04449	COG5577	PFAM Coat F domain
S101441_04450	COG1733	regulation of RNA biosynthetic process
S101441_04451	COG1227	inorganic diphosphatase activity
S101441_04454	COG2271	Major facilitator Superfamily
S101441_04455	COG2271	Major facilitator Superfamily
S101441_04456	COG4978	Transcriptional regulator
S101441_04456	COG0789	Transcriptional regulator
S101441_04458	COG4319	ketosteroid isomerase
S101441_04459	COG1357	PFAM Pentapeptide repeats (8 copies)
S101441_04460	COG2814	Major facilitator Superfamily
S101441_04461	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101441_04462	COG1846	Transcriptional regulator
S101441_04463	COG2153	protein acetylation
S101441_04464	COG2364	Membrane
S101441_04465	COG0456	acetyltransferase
S101441_04466	COG2315	Protein conserved in bacteria
S101441_04467	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101441_04468	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S101441_04469	COG1331	Highly conserved protein containing a thioredoxin domain
S101441_04470	COG1266	CAAX protease self-immunity
S101441_04471	COG2814	Major facilitator Superfamily
S101441_04471	COG0477	Major facilitator Superfamily
S101441_04472	COG0110	maltose O-acetyltransferase activity
S101441_04473	COG0346	lactoylglutathione lyase activity
S101441_04474	COG1609	Transcriptional regulator
S101441_04475	COG1609	Transcriptional regulator
S101441_04476	COG0708	Exodeoxyribonuclease III
S101441_04477	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
S101441_04478	COG0629	single-stranded DNA binding
S101441_04479	COG0360	Binds together with S18 to 16S ribosomal RNA
S101441_04480	COG0012	GTP binding
S101441_04481	COG0243	molybdopterin cofactor binding
S101441_04482	COG4481	Protein conserved in bacteria
S101441_04483	COG3949	Membrane
S101441_04486	COG2801	Transposase and inactivated derivatives
S101441_04487	COG1475	DNA binding
S101441_04488	COG1192	Involved in chromosome partitioning
S101441_04490	COG1475	DNA binding
S101441_04491	COG0357	Ribosomal RNA small subunit methyltransferase G
S101441_04492	COG0445	tRNA wobble uridine modification
S101441_04493	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
S101441_04494	COG1847	R3H domain protein
S101441_04495	COG0706	membrane insertase activity
S101441_04496	COG0594	ribonuclease P activity
S101441_04498	COG0457	Tetratricopeptide repeat