locus-tag	class	description
S101444_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
S101444_00002	COG0592	DNA-directed DNA polymerase activity
S101444_00003	COG2501	S4 domain
S101444_00004	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
S101444_00006	COG0187	DNA topoisomerase II activity
S101444_00007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101444_00014	COG0517	IMP dehydrogenase activity
S101444_00014	COG0516	GMP reductase activity
S101444_00015	COG1686	Belongs to the peptidase S11 family
S101444_00016	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
S101444_00017	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
S101444_00018	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
S101444_00020	COG1428	Deoxynucleoside kinase
S101444_00021	COG1428	Deoxynucleoside kinase
S101444_00022	COG1388	LysM domain
S101444_00022	COG3858	chitin binding
S101444_00023	COG1335	isochorismatase
S101444_00024	COG0590	tRNA wobble adenosine to inosine editing
S101444_00025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
S101444_00026	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
S101444_00027	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
S101444_00036	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
S101444_00037	COG3853	Toxic anion resistance protein (TelA)
S101444_00038	COG1982	Orn Lys Arg decarboxylase major
S101444_00039	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
S101444_00040	COG3870	Protein conserved in bacteria
S101444_00041	COG1728	Protein conserved in bacteria
S101444_00042	COG0470	DNA polymerase III
S101444_00043	COG1774	PSP1 C-terminal conserved region
S101444_00044	COG4467	Involved in initiation control of chromosome replication
S101444_00045	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
S101444_00046	COG2827	Endonuclease containing a URI domain
S101444_00047	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
S101444_00048	COG2002	toxin-antitoxin pair type II binding
S101444_00049	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101444_00049	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101444_00050	COG0084	hydrolase, TatD family'
S101444_00051	COG3584	3D domain protein
S101444_00051	COG3583	domain protein
S101444_00052	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101444_00053	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
S101444_00055	COG4466	Protein conserved in bacteria
S101444_00057	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
S101444_00058	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101444_00059	COG0251	oxidation-reduction process
S101444_00060	COG2088	sporulation resulting in formation of a cellular spore
S101444_00061	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
S101444_00062	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
S101444_00063	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
S101444_00064	COG0193	aminoacyl-tRNA hydrolase activity
S101444_00066	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
S101444_00067	COG2002	toxin-antitoxin pair type II binding
S101444_00068	COG2244	polysaccharide biosynthetic process
S101444_00069	COG3956	TIGRFAM MazG family protein
S101444_00070	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
S101444_00073	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
S101444_00074	COG1098	S1 RNA binding domain
S101444_00077	COG2208	phosphoserine phosphatase activity
S101444_00078	COG2304	oxidoreductase activity
S101444_00079	COG0515	serine threonine protein kinase
S101444_00080	COG0037	tRNA processing
S101444_00082	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S101444_00083	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
S101444_00084	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
S101444_00085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101444_00086	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101444_00087	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101444_00088	COG0512	Glutamine amidotransferase of anthranilate synthase
S101444_00089	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101444_00090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
S101444_00091	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
S101444_00092	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
S101444_00093	COG1396	sequence-specific DNA binding
S101444_00094	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101444_00095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
S101444_00111	COG4463	regulation of RNA biosynthetic process
S101444_00112	COG3880	PFAM UvrB UvrC protein
S101444_00113	COG3869	Catalyzes the specific phosphorylation of arginine residues in
S101444_00114	COG0542	response to heat
S101444_00115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
S101444_00116	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
S101444_00117	COG4956	integral membrane protein (PIN domain superfamily)
S101444_00118	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
S101444_00119	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
S101444_00120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
S101444_00121	COG1045	serine acetyltransferase
S101444_00122	COG0215	cysteine-tRNA ligase activity
S101444_00123	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
S101444_00124	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101444_00125	COG3688	RNA-binding protein containing a PIN domain
S101444_00126	COG1595	DNA-templated transcription, initiation
S101444_00127	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101444_00128	COG0250	Participates in transcription elongation, termination and antitermination
S101444_00129	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
S101444_00130	COG0081	regulation of translation
S101444_00131	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
S101444_00132	COG0222	ribosome binding
S101444_00133	COG2813	Specifically methylates the guanine in position
S101444_00134	COG0085	RNA polymerase activity
S101444_00135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
S101444_00136	COG1358	cellular component organization or biogenesis
S101444_00137	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
S101444_00138	COG0049	tRNA binding
S101444_00139	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
S101444_00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
S101444_00141	COG0596	Alpha beta hydrolase
S101444_00142	COG0051	transcription antitermination factor activity, RNA binding
S101444_00143	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
S101444_00144	COG0088	Forms part of the polypeptide exit tunnel
S101444_00145	COG0089	rRNA binding
S101444_00146	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
S101444_00147	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
S101444_00148	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
S101444_00149	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
S101444_00150	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
S101444_00151	COG0255	Belongs to the universal ribosomal protein uL29 family
S101444_00152	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
S101444_00153	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
S101444_00155	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
S101444_00157	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
S101444_00158	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
S101444_00159	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
S101444_00161	COG1841	ribosomal large subunit assembly
S101444_00162	COG0200	Binds to the 23S rRNA
S101444_00163	COG0201	protein transport
S101444_00164	COG0563	adenylate kinase activity
S101444_00165	COG0024	Methionine aminopeptidase
S101444_00166	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
S101444_00167	COG0257	Belongs to the bacterial ribosomal protein bL36 family
S101444_00168	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
S101444_00169	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
S101444_00170	COG0202	RNA polymerase activity
S101444_00171	COG0203	ribosomal protein L17
S101444_00172	COG1122	ATPase activity
S101444_00173	COG1122	ATPase activity
S101444_00174	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101444_00175	COG0101	tRNA pseudouridine synthase activity
S101444_00176	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
S101444_00177	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
S101444_00178	COG2226	methyltransferase
S101444_00180	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101444_00181	COG0489	protein tyrosine kinase activity
S101444_00183	COG2194	sulfuric ester hydrolase activity
S101444_00184	COG0726	polysaccharide deacetylase
S101444_00200	COG0659	secondary active sulfate transmembrane transporter activity
S101444_00202	COG0385	Bile acid
S101444_00203	COG2819	hydrolase of the alpha beta superfamily
S101444_00204	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_00205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_00206	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101444_00207	COG2207	Transcriptional regulator
S101444_00207	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101444_00208	COG3876	Protein conserved in bacteria
S101444_00209	COG1472	Belongs to the glycosyl hydrolase 3 family
S101444_00210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101444_00211	COG1263	PTS System
S101444_00211	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_00212	COG1737	Transcriptional regulator
S101444_00213	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
S101444_00214	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_00215	COG1683	Conserved Protein
S101444_00221	COG1595	DNA-templated transcription, initiation
S101444_00222	COG5662	AntiSigma factor
S101444_00223	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101444_00224	COG4856	YbbR-like protein
S101444_00225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S101444_00226	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
S101444_00227	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
S101444_00228	COG2169	Transcriptional regulator
S101444_00229	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101444_00230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101444_00231	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S101444_00232	COG3002	Belongs to the UPF0753 family
S101444_00233	COG0288	reversible hydration of carbon dioxide
S101444_00235	COG5609	conserved protein (DUF2294)
S101444_00236	COG0640	Transcriptional regulator
S101444_00237	COG2814	Major facilitator Superfamily
S101444_00239	COG0596	Alpha beta hydrolase
S101444_00240	COG0745	RESPONSE REGULATOR receiver
S101444_00241	COG0642	Histidine kinase
S101444_00243	COG0515	serine threonine protein kinase
S101444_00246	COG1113	amino acid transport
S101444_00249	COG2602	Beta-lactamase
S101444_00250	COG2124	cytochrome p450
S101444_00252	COG0531	amino acid
S101444_00253	COG0584	glycerophosphoryl diester phosphodiesterase
S101444_00254	COG2271	Major facilitator Superfamily
S101444_00256	COG1846	Transcriptional regulator
S101444_00256	COG0456	acetyltransferase
S101444_00257	COG2271	Major facilitator Superfamily
S101444_00258	COG0697	spore germination
S101444_00259	COG1917	Cupin 2, conserved barrel domain protein
S101444_00259	COG2207	Transcriptional regulator
S101444_00264	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
S101444_00265	COG3591	Belongs to the peptidase S1B family
S101444_00267	COG0596	Alpha beta hydrolase
S101444_00268	COG1183	phosphatidylcholine synthase activity
S101444_00269	COG0586	Pfam SNARE associated Golgi protein
S101444_00270	COG0688	phosphatidylethanolamine metabolic process
S101444_00272	COG2312	Erythromycin esterase
S101444_00273	COG2207	Transcriptional regulator
S101444_00275	COG1301	dicarboxylic acid transport
S101444_00276	COG2190	(PTS) system
S101444_00276	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_00276	COG1263	PTS System
S101444_00277	COG0363	glucosamine-6-phosphate deaminase activity
S101444_00280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101444_00281	COG0833	amino acid
S101444_00282	COG2040	homocysteine
S101444_00284	COG1115	amino acid carrier protein
S101444_00285	COG2066	Belongs to the glutaminase family
S101444_00286	COG4191	Histidine kinase
S101444_00287	COG0784	Response regulator, receiver
S101444_00288	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
S101444_00289	COG1012	belongs to the aldehyde dehydrogenase family
S101444_00290	COG2271	Major facilitator Superfamily
S101444_00291	COG4948	Mandelate Racemase Muconate Lactonizing
S101444_00292	COG2186	Transcriptional regulator
S101444_00293	COG2721	sulfolactate sulfo-lyase activity
S101444_00294	COG3173	Aminoglycoside phosphotransferase
S101444_00296	COG0697	spore germination
S101444_00297	COG0745	RESPONSE REGULATOR receiver
S101444_00298	COG2205	protein histidine kinase activity
S101444_00299	COG1131	(ABC) transporter
S101444_00302	COG3773	Cell wall hydrolase
S101444_00303	COG2304	oxidoreductase activity
S101444_00304	COG3540	Alkaline phosphatase
S101444_00305	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101444_00306	COG0805	protein transport
S101444_00307	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
S101444_00308	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101444_00309	COG0477	Major facilitator Superfamily
S101444_00310	COG1309	transcriptional regulator
S101444_00311	COG0252	asparaginase activity
S101444_00312	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S101444_00313	COG1714	RDD family
S101444_00314	COG3012	SEC-C Motif Domain Protein
S101444_00314	COG1405	negative regulation of cell septum assembly
S101444_00315	COG3290	protein histidine kinase activity
S101444_00316	COG3279	Response regulator of the LytR AlgR family
S101444_00317	COG4555	ABC transporter
S101444_00318	COG1668	transmembrane transport
S101444_00319	COG0667	Aldo Keto reductase
S101444_00321	COG1595	DNA-templated transcription, initiation
S101444_00322	COG1595	DNA-templated transcription, initiation
S101444_00323	COG1876	peptidase activity
S101444_00324	COG0457	Tetratricopeptide repeat
S101444_00325	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_00326	COG0366	Alpha amylase catalytic
S101444_00327	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101444_00328	COG1121	(ABC) transporter
S101444_00329	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101444_00330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101444_00331	COG2310	stress, protein
S101444_00332	COG2310	stress, protein
S101444_00333	COG2310	stress, protein
S101444_00334	COG0861	Integral membrane protein TerC family
S101444_00336	COG3853	Toxic anion resistance protein (TelA)
S101444_00337	COG0477	Major facilitator Superfamily
S101444_00338	COG2814	Major facilitator Superfamily
S101444_00339	COG0640	Transcriptional regulator
S101444_00340	COG0517	IMP dehydrogenase activity
S101444_00340	COG4175	Glycine betaine
S101444_00341	COG4176	ABC-type proline glycine betaine transport system permease component
S101444_00342	COG2113	Glycine betaine
S101444_00343	COG1473	amidohydrolase
S101444_00344	COG1288	antiporter activity
S101444_00346	COG0366	Alpha amylase catalytic
S101444_00347	COG0039	L-malate dehydrogenase activity
S101444_00348	COG1620	l-lactate permease
S101444_00349	COG2814	Major facilitator Superfamily
S101444_00350	COG1846	Transcriptional regulator
S101444_00351	COG1280	lysine exporter protein (LysE YggA)
S101444_00352	COG3403	YqcI/YcgG family
S101444_00353	COG1113	amino acid transport
S101444_00354	COG3665	Urea carboxylase-associated protein
S101444_00355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
S101444_00356	COG1660	Displays ATPase and GTPase activities
S101444_00357	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
S101444_00358	COG2226	methyltransferase
S101444_00359	COG0583	DNA-binding transcription factor activity
S101444_00360	COG3458	cephalosporin-C deacetylase activity
S101444_00361	COG3541	Predicted nucleotidyltransferase
S101444_00362	COG0506	proline dehydrogenase activity
S101444_00363	COG1012	belongs to the aldehyde dehydrogenase family
S101444_00364	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101444_00365	COG2508	Transcriptional regulator
S101444_00366	COG3689	TIGRFAM TIGR03943 family protein
S101444_00367	COG0701	Predicted permease
S101444_00368	COG2267	carboxylic ester hydrolase activity
S101444_00369	COG0492	ferredoxin-NADP+ reductase activity
S101444_00370	COG1587	Uroporphyrinogen-III synthase
S101444_00370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101444_00371	COG2146	nitrite reductase [NAD(P)H] activity
S101444_00372	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101444_00373	COG0243	molybdopterin cofactor binding
S101444_00374	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101444_00375	COG2223	nitrite transmembrane transporter activity
S101444_00376	COG1469	GTP cyclohydrolase I activity
S101444_00377	COG1376	ErfK ybiS ycfS ynhG family protein
S101444_00378	COG0523	cobalamin synthesis protein
S101444_00379	COG0765	amino acid transport
S101444_00380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101444_00382	COG1714	RDD family
S101444_00384	COG1846	Transcriptional regulator
S101444_00386	COG3842	ATPase activity
S101444_00387	COG2723	6-phospho-beta-galactosidase activity
S101444_00389	COG3209	COG3209 Rhs family protein
S101444_00390	COG0840	transmembrane signaling receptor activity
S101444_00390	COG3290	protein histidine kinase activity
S101444_00391	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
S101444_00392	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
S101444_00393	COG1733	regulation of RNA biosynthetic process
S101444_00394	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101444_00395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101444_00396	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101444_00397	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
S101444_00398	COG2814	Major facilitator Superfamily
S101444_00400	COG0697	spore germination
S101444_00401	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101444_00403	COG2364	Membrane
S101444_00404	COG1126	abc transporter atp-binding protein
S101444_00405	COG0765	amino acid transport
S101444_00406	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101444_00407	COG0583	DNA-binding transcription factor activity
S101444_00408	COG0163	prenyltransferase activity
S101444_00409	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S101444_00412	COG0596	Alpha beta hydrolase
S101444_00413	COG3104	oligopeptide transport
S101444_00414	COG5434	Belongs to the glycosyl hydrolase 28 family
S101444_00416	COG0697	spore germination
S101444_00418	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101444_00419	COG1136	(ABC) transporter
S101444_00420	COG0577	efflux transmembrane transporter activity
S101444_00421	COG0745	RESPONSE REGULATOR receiver
S101444_00422	COG3850	Histidine kinase
S101444_00422	COG5002	protein histidine kinase activity
S101444_00423	COG0457	Tetratricopeptide repeat
S101444_00426	COG0527	aspartate kinase activity
S101444_00427	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_00428	COG4605	iron ion homeostasis
S101444_00429	COG4604	ABC transporter, ATP-binding protein
S101444_00430	COG4607	ABC-type enterochelin transport system periplasmic component
S101444_00432	COG2814	Major facilitator Superfamily
S101444_00433	COG1309	transcriptional regulator
S101444_00434	COG0778	Nitroreductase
S101444_00435	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101444_00436	COG0640	Transcriptional regulator
S101444_00437	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101444_00438	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S101444_00439	COG1012	belongs to the aldehyde dehydrogenase family
S101444_00440	COG4975	Glucose uptake
S101444_00441	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_00442	COG4549	nuclear export factor GLE1
S101444_00443	COG2372	response to copper ion
S101444_00443	COG1276	copper resistance
S101444_00444	COG1349	DNA-binding transcription factor activity
S101444_00446	COG2213	PTS system mannitol-specific
S101444_00447	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_00448	COG0246	Mannitol dehydrogenase
S101444_00449	COG0246	Mannitol dehydrogenase
S101444_00450	COG0473	3-isopropylmalate dehydrogenase activity
S101444_00452	COG0681	Belongs to the peptidase S26 family
S101444_00453	COG0412	Dienelactone hydrolase
S101444_00454	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S101444_00456	COG0561	phosphatase activity
S101444_00457	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
S101444_00458	COG1914	H( )-stimulated, divalent metal cation uptake system
S101444_00459	COG4336	lyase activity
S101444_00460	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
S101444_00461	COG1984	allophanate hydrolase subunit 2
S101444_00462	COG1414	Transcriptional regulator
S101444_00463	COG2755	lipolytic protein G-D-S-L family
S101444_00465	COG2329	Antibiotic biosynthesis monooxygenase
S101444_00466	COG0768	penicillin binding
S101444_00467	COG4989	oxidoreductase activity
S101444_00468	COG3711	transcriptional antiterminator
S101444_00469	COG0318	PFAM AMP-dependent synthetase and ligase
S101444_00470	COG2226	methyltransferase
S101444_00471	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_00472	COG1917	Cupin 2, conserved barrel domain protein
S101444_00473	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_00474	COG3871	stress protein (general stress protein 26)
S101444_00476	COG2814	Major facilitator Superfamily
S101444_00477	COG1522	sequence-specific DNA binding
S101444_00478	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101444_00478	COG0551	DNA topoisomerase type I activity
S101444_00479	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
S101444_00480	COG3706	GGDEF domain
S101444_00481	COG5298	Protein conserved in bacteria
S101444_00482	COG1215	transferase activity, transferring glycosyl groups
S101444_00484	COG0531	amino acid
S101444_00485	COG0494	nUDIX hydrolase
S101444_00486	COG0028	Belongs to the TPP enzyme family
S101444_00492	COG1914	H( )-stimulated, divalent metal cation uptake system
S101444_00493	COG2261	transglycosylase associated protein
S101444_00494	COG4876	unkown
S101444_00495	COG2217	Heavy metal translocating P-type atpase
S101444_00496	COG3729	General stress protein
S101444_00497	COG0662	Cupin 2, conserved barrel domain protein
S101444_00498	COG2329	Antibiotic biosynthesis monooxygenase
S101444_00499	COG3546	catalase activity
S101444_00500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
S101444_00501	COG3290	protein histidine kinase activity
S101444_00502	COG4565	transcriptional regulatory protein
S101444_00503	COG1301	dicarboxylic acid transport
S101444_00504	COG0628	permease
S101444_00506	COG1131	(ABC) transporter
S101444_00507	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101444_00509	COG1960	acyl-CoA dehydrogenase activity
S101444_00512	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101444_00513	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_00514	COG1181	Belongs to the D-alanine--D-alanine ligase family
S101444_00515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
S101444_00516	COG0513	Belongs to the DEAD box helicase family
S101444_00517	COG3402	PFAM membrane-flanked domain
S101444_00518	COG3428	Bacterial PH domain
S101444_00519	COG0705	Rhomboid family
S101444_00520	COG0736	holo-[acyl-carrier-protein] synthase activity
S101444_00521	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
S101444_00522	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101444_00523	COG0864	Transcriptional regulator
S101444_00524	COG2337	Toxic component of a toxin-antitoxin (TA) module
S101444_00525	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_00526	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_00527	COG2172	sigma factor antagonist activity
S101444_00528	COG2208	phosphoserine phosphatase activity
S101444_00529	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_00530	COG2172	sigma factor antagonist activity
S101444_00531	COG1191	sigma factor activity
S101444_00532	COG2208	phosphoserine phosphatase activity
S101444_00533	COG2183	response to ionizing radiation
S101444_00534	COG3091	SprT-like family
S101444_00544	COG0640	Transcriptional regulator
S101444_00545	COG0640	Transcriptional regulator
S101444_00546	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101444_00547	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101444_00548	COG0582	viral genome integration into host DNA
S101444_00549	COG2856	Zn peptidase
S101444_00550	COG1396	sequence-specific DNA binding
S101444_00555	COG1674	ftsk spoiiie
S101444_00556	COG2946	Replication initiation factor
S101444_00563	COG0433	COG0433 Predicted ATPase
S101444_00565	COG5644	endopeptidase inhibitor activity
S101444_00566	COG0791	NLP P60 protein
S101444_00566	COG0741	lytic transglycosylase activity
S101444_00569	COG0457	Tetratricopeptide repeat
S101444_00573	COG0583	DNA-binding transcription factor activity
S101444_00574	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_00576	COG5444	nuclease activity
S101444_00577	COG1476	TRANSCRIPTIONal
S101444_00582	COG0693	protein deglycase activity
S101444_00583	COG1278	Cold shock
S101444_00584	COG1329	Transcriptional regulator
S101444_00585	COG0697	spore germination
S101444_00586	COG1917	Cupin 2, conserved barrel domain protein
S101444_00586	COG2207	Transcriptional regulator
S101444_00587	COG0697	spore germination
S101444_00588	COG3708	Transcriptional regulator
S101444_00588	COG2207	Transcriptional regulator
S101444_00589	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101444_00590	COG0477	Major facilitator Superfamily
S101444_00591	COG0477	Major facilitator Superfamily
S101444_00593	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
S101444_00596	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_00597	COG1309	transcriptional regulator
S101444_00598	COG0697	spore germination
S101444_00599	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101444_00600	COG2030	dehydratase
S101444_00601	COG3545	Serine hydrolase
S101444_00602	COG1733	regulation of RNA biosynthetic process
S101444_00603	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101444_00604	COG1733	regulation of RNA biosynthetic process
S101444_00605	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101444_00606	COG2814	Major facilitator Superfamily
S101444_00607	COG1309	transcriptional regulator
S101444_00608	COG0640	Transcriptional regulator
S101444_00609	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101444_00610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_00611	COG0697	spore germination
S101444_00612	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101444_00613	COG0076	glutamate decarboxylase activity
S101444_00614	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S101444_00615	COG0640	Transcriptional regulator
S101444_00616	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S101444_00618	COG4585	Histidine kinase
S101444_00619	COG2197	response regulator
S101444_00620	COG2409	Drug exporters of the RND superfamily
S101444_00621	COG1811	Na channel or pump
S101444_00622	COG4978	Transcriptional regulator
S101444_00622	COG0789	Transcriptional regulator
S101444_00623	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101444_00624	COG0778	Nitroreductase
S101444_00625	COG0346	lactoylglutathione lyase activity
S101444_00626	COG2259	Doxx family
S101444_00627	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_00631	COG2323	membrane
S101444_00632	COG2323	membrane
S101444_00633	COG0071	Belongs to the small heat shock protein (HSP20) family
S101444_00636	COG1309	transcriptional regulator
S101444_00638	COG0456	acetyltransferase
S101444_00640	COG1113	amino acid transport
S101444_00641	COG2318	DinB family
S101444_00642	COG1846	Transcriptional regulator
S101444_00643	COG1033	growth of symbiont in host cell
S101444_00643	COG2409	Drug exporters of the RND superfamily
S101444_00644	COG0778	Nitroreductase
S101444_00645	COG1846	Transcriptional regulator
S101444_00646	COG2814	Major facilitator Superfamily
S101444_00647	COG0730	response to heat
S101444_00648	COG1802	Transcriptional regulator
S101444_00649	COG1388	LysM domain
S101444_00649	COG3858	chitin binding
S101444_00650	COG1819	glycosyl
S101444_00652	COG1785	Belongs to the alkaline phosphatase family
S101444_00653	COG5646	InterPro IPR014922
S101444_00655	COG0454	-acetyltransferase
S101444_00656	COG1078	dGTPase activity
S101444_00657	COG1388	LysM domain
S101444_00658	COG2814	Major facilitator Superfamily
S101444_00659	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101444_00660	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101444_00661	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101444_00662	COG2723	6-phospho-beta-galactosidase activity
S101444_00663	COG2188	Transcriptional regulator
S101444_00664	COG1940	carbohydrate kinase activity
S101444_00665	COG1482	cell wall glycoprotein biosynthetic process
S101444_00666	COG4124	Belongs to the glycosyl hydrolase 26 family
S101444_00675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
S101444_00676	COG0802	atpase or kinase
S101444_00677	COG1214	PFAM Peptidase M22, glycoprotease
S101444_00678	COG0456	acetyltransferase
S101444_00679	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
S101444_00680	COG0488	(ABC) transporter
S101444_00681	COG0315	cyclic pyranopterin monophosphate synthase activity
S101444_00682	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
S101444_00683	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101444_00684	COG0805	protein transport
S101444_00686	COG1266	CAAX protease self-immunity
S101444_00687	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
S101444_00688	COG0459	protein refolding
S101444_00689	COG1073	alpha beta
S101444_00690	COG0457	Tetratricopeptide repeat
S101444_00691	COG1063	alcohol dehydrogenase
S101444_00692	COG2211	Major facilitator Superfamily
S101444_00693	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101444_00694	COG1842	Phage shock protein A
S101444_00695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101444_00696	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
S101444_00697	COG4260	virion core protein, lumpy skin disease virus
S101444_00699	COG2814	Major facilitator Superfamily
S101444_00700	COG1063	alcohol dehydrogenase
S101444_00701	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
S101444_00702	COG0823	Involved in the tonB-independent uptake of proteins
S101444_00705	COG2267	carboxylic ester hydrolase activity
S101444_00707	COG2132	Multicopper oxidase
S101444_00708	COG1113	amino acid transport
S101444_00709	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101444_00710	COG0714	Associated with various cellular activities
S101444_00711	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
S101444_00712	COG1305	Transglutaminase-like
S101444_00713	COG0519	Catalyzes the synthesis of GMP from XMP
S101444_00713	COG0518	GMP synthase (glutamine-hydrolyzing) activity
S101444_00716	COG2252	PERMEase
S101444_00717	COG3064	Membrane
S101444_00719	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
S101444_00721	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
S101444_00722	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
S101444_00723	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
S101444_00724	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
S101444_00725	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S101444_00726	COG0047	phosphoribosylformylglycinamidine synthase activity
S101444_00727	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S101444_00728	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
S101444_00729	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
S101444_00730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
S101444_00731	COG0138	bifunctional purine biosynthesis protein purh
S101444_00732	COG0151	Belongs to the GarS family
S101444_00733	COG1522	sequence-specific DNA binding
S101444_00734	COG0531	amino acid
S101444_00736	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S101444_00737	COG1470	cell adhesion involved in biofilm formation
S101444_00738	COG4496	protein, YerC YecD
S101444_00739	COG0069	glutamate synthase activity
S101444_00740	COG0069	glutamate synthase activity
S101444_00742	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
S101444_00743	COG0210	DNA helicase
S101444_00744	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
S101444_00745	COG4851	CamS sex pheromone cAM373 precursor
S101444_00746	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101444_00747	COG1285	pathogenesis
S101444_00748	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101444_00749	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
S101444_00750	COG0154	amidase activity
S101444_00751	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
S101444_00752	COG1309	transcriptional regulator
S101444_00753	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S101444_00754	COG1597	lipid kinase activity
S101444_00755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101444_00764	COG0457	Tetratricopeptide repeat
S101444_00766	COG0457	Tetratricopeptide repeat
S101444_00770	COG5444	nuclease activity
S101444_00772	COG3586	endonuclease activity
S101444_00774	COG0457	Tetratricopeptide repeat
S101444_00776	COG0217	transcriptional regulatory protein
S101444_00778	COG1309	transcriptional regulator
S101444_00779	COG3631	Ketosteroid isomerase-related protein
S101444_00780	COG0702	epimerase
S101444_00783	COG3546	catalase activity
S101444_00784	COG0454	-acetyltransferase
S101444_00786	COG5578	integral membrane protein
S101444_00787	COG2972	Histidine kinase
S101444_00788	COG2207	Transcriptional regulator
S101444_00788	COG4753	response regulator
S101444_00789	COG1653	transport
S101444_00790	COG1175	transmembrane transport
S101444_00791	COG0395	ABC-type sugar transport system, permease component
S101444_00792	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
S101444_00793	COG2207	Transcriptional regulator
S101444_00794	COG2755	lipolytic protein G-D-S-L family
S101444_00796	COG5578	integral membrane protein
S101444_00797	COG3401	FG-GAP repeat protein
S101444_00798	COG3401	FG-GAP repeat protein
S101444_00799	COG2755	lipolytic protein G-D-S-L family
S101444_00800	COG1874	Beta-galactosidase
S101444_00802	COG1653	transport
S101444_00803	COG4209	transmembrane transport
S101444_00804	COG0395	ABC-type sugar transport system, permease component
S101444_00805	COG1486	melibiose metabolic process
S101444_00806	COG2323	membrane
S101444_00807	COG2329	Antibiotic biosynthesis monooxygenase
S101444_00808	COG0346	lactoylglutathione lyase activity
S101444_00810	COG5583	Uncharacterized small protein (DUF2292)
S101444_00811	COG0670	Belongs to the BI1 family
S101444_00812	COG0697	spore germination
S101444_00813	COG1846	Transcriptional regulator
S101444_00814	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101444_00816	COG2124	cytochrome p450
S101444_00816	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101444_00817	COG1368	sulfuric ester hydrolase activity
S101444_00818	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
S101444_00819	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101444_00820	COG1442	glycosyl transferase family 8
S101444_00821	COG1216	Glycosyl transferase, family 2
S101444_00822	COG1442	glycosyl transferase family 8
S101444_00823	COG2223	nitrite transmembrane transporter activity
S101444_00824	COG1011	Hydrolase
S101444_00825	COG0531	amino acid
S101444_00826	COG1012	belongs to the aldehyde dehydrogenase family
S101444_00827	COG0840	transmembrane signaling receptor activity
S101444_00828	COG0488	(ABC) transporter
S101444_00830	COG0789	Transcriptional regulator
S101444_00831	COG2814	Major facilitator Superfamily
S101444_00833	COG0488	(ABC) transporter
S101444_00834	COG0513	Belongs to the DEAD box helicase family
S101444_00835	COG0456	acetyltransferase
S101444_00836	COG2130	NADP-dependent
S101444_00837	COG1120	ATPase activity
S101444_00838	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_00839	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_00840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
S101444_00843	COG3866	Pectate lyase
S101444_00844	COG0471	metal ion transport
S101444_00845	COG3290	protein histidine kinase activity
S101444_00846	COG4565	transcriptional regulatory protein
S101444_00847	COG3181	Tripartite tricarboxylate transporter family receptor
S101444_00848	COG2851	Citrate transporter
S101444_00849	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101444_00850	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
S101444_00851	COG1254	Belongs to the acylphosphatase family
S101444_00852	COG2258	MOSC domain
S101444_00856	COG0024	Methionine aminopeptidase
S101444_00857	COG1263	PTS System
S101444_00857	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_00858	COG1263	PTS System
S101444_00858	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_00859	COG1368	sulfuric ester hydrolase activity
S101444_00861	COG1115	amino acid carrier protein
S101444_00862	COG0697	spore germination
S101444_00863	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_00863	COG1263	PTS System
S101444_00864	COG0366	Alpha amylase catalytic
S101444_00865	COG2188	Transcriptional regulator
S101444_00866	COG0778	Nitroreductase
S101444_00867	COG0737	Belongs to the 5'-nucleotidase family
S101444_00868	COG0693	protein deglycase activity
S101444_00869	COG2814	Major facilitator Superfamily
S101444_00870	COG4840	Belongs to the UPF0435 family
S101444_00871	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101444_00872	COG4980	gas vesicle protein
S101444_00873	COG1295	ribonuclease BN
S101444_00875	COG0477	Major facilitator Superfamily
S101444_00876	COG0387	Pfam Sodium calcium exchanger
S101444_00878	COG0668	transmembrane transport
S101444_00879	COG0535	radical SAM domain protein
S101444_00881	COG0726	polysaccharide deacetylase
S101444_00882	COG2084	Dehydrogenase
S101444_00883	COG0598	Magnesium transport protein CorA
S101444_00884	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
S101444_00885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101444_00887	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101444_00888	COG4637	Psort location Cytoplasmic, score
S101444_00890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101444_00891	COG0022	dehydrogenase e1 component
S101444_00892	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101444_00893	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101444_00894	COG3284	Transcriptional regulator
S101444_00896	COG1742	UPF0060 membrane protein
S101444_00901	COG4842	Belongs to the WXG100 family
S101444_00902	COG1486	melibiose metabolic process
S101444_00903	COG1737	Transcriptional regulator
S101444_00904	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_00904	COG1263	PTS System
S101444_00905	COG5434	Belongs to the glycosyl hydrolase 28 family
S101444_00906	COG1132	(ABC) transporter
S101444_00907	COG1132	(ABC) transporter
S101444_00908	COG2259	Doxx family
S101444_00909	COG2514	catechol 2,3-dioxygenase activity
S101444_00910	COG4585	Histidine kinase
S101444_00911	COG2197	response regulator
S101444_00912	COG1131	(ABC) transporter
S101444_00913	COG1511	domain protein
S101444_00913	COG0842	Transport permease protein
S101444_00914	COG0842	Transport permease protein
S101444_00915	COG1695	Transcriptional regulator
S101444_00916	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S101444_00917	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
S101444_00918	COG1309	transcriptional regulator
S101444_00919	COG2814	Major facilitator Superfamily
S101444_00920	COG2318	DinB family
S101444_00921	COG2814	Major facilitator Superfamily
S101444_00922	COG1846	Transcriptional regulator
S101444_00923	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
S101444_00923	COG0392	lysyltransferase activity
S101444_00924	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101444_00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_00926	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_00927	COG0384	phenazine biosynthesis protein PhzF
S101444_00928	COG0778	Nitroreductase
S101444_00931	COG1090	epimerase
S101444_00932	COG2137	regulation of response to DNA damage stimulus
S101444_00934	COG2814	Major facilitator Superfamily
S101444_00937	COG3103	Sh3 type 3 domain protein
S101444_00938	COG5658	integral membrane protein
S101444_00939	COG0596	Alpha beta hydrolase
S101444_00940	COG0463	Glycosyl transferase, family 2
S101444_00941	COG4485	Bacterial membrane protein, YfhO
S101444_00942	COG1988	membrane-bound metal-dependent
S101444_00943	COG1194	a g-specific adenine glycosylase
S101444_00945	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_00948	COG3557	Belongs to the UPF0374 family
S101444_00949	COG1132	(ABC) transporter
S101444_00950	COG4129	membrane
S101444_00951	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
S101444_00952	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
S101444_00953	COG0735	belongs to the Fur family
S101444_00975	COG4326	sporulation control protein
S101444_00977	COG3340	Belongs to the peptidase S51 family
S101444_00978	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
S101444_00980	COG0753	catalase activity
S101444_00981	COG1116	anion transmembrane transporter activity
S101444_00982	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101444_00983	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101444_00984	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101444_00986	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
S101444_00988	COG1476	TRANSCRIPTIONal
S101444_00990	COG3382	B3 4 domain protein
S101444_00991	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
S101444_00993	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
S101444_00994	COG0789	Transcriptional regulator
S101444_00995	COG1664	Polymer-forming cytoskeletal
S101444_00996	COG1664	Polymer-forming cytoskeletal
S101444_00997	COG2766	serine protein kinase
S101444_00998	COG2718	Belongs to the UPF0229 family
S101444_00999	COG1846	Transcriptional regulator
S101444_01000	COG1566	PFAM secretion protein HlyD family protein
S101444_01001	COG2814	Major facilitator Superfamily
S101444_01002	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101444_01006	COG1725	Transcriptional regulator
S101444_01007	COG1131	(ABC) transporter
S101444_01008	COG1131	(ABC) transporter
S101444_01009	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101444_01010	COG1278	Cold shock
S101444_01011	COG1464	Belongs to the NlpA lipoprotein family
S101444_01012	COG3706	GGDEF domain
S101444_01013	COG1823	symporter activity
S101444_01014	COG5444	nuclease activity
S101444_01019	COG0582	viral genome integration into host DNA
S101444_01029	COG0433	COG0433 Predicted ATPase
S101444_01031	COG5644	endopeptidase inhibitor activity
S101444_01032	COG0741	lytic transglycosylase activity
S101444_01032	COG0791	NLP P60 protein
S101444_01038	COG0457	Tetratricopeptide repeat
S101444_01043	COG5577	PFAM Coat F domain
S101444_01044	COG0737	Belongs to the 5'-nucleotidase family
S101444_01044	COG1525	nuclease
S101444_01044	COG4085	toxin activity
S101444_01045	COG3764	Sortase (surface protein transpeptidase)
S101444_01046	COG0564	pseudouridine synthase activity
S101444_01048	COG0517	IMP dehydrogenase activity
S101444_01049	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101444_01050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101444_01050	COG3153	acetyltransferase
S101444_01051	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101444_01052	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
S101444_01053	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
S101444_01054	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
S101444_01055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
S101444_01056	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S101444_01057	COG4585	Histidine kinase
S101444_01057	COG2203	Gaf domain
S101444_01058	COG2197	response regulator
S101444_01059	COG0431	NADPH-dependent FMN reductase
S101444_01062	COG0791	NLP P60 protein
S101444_01062	COG1388	LysM domain
S101444_01063	COG1959	2 iron, 2 sulfur cluster binding
S101444_01064	COG0668	transmembrane transport
S101444_01065	COG2719	SpoVR family
S101444_01066	COG1785	Belongs to the alkaline phosphatase family
S101444_01067	COG1388	LysM domain
S101444_01067	COG0791	NLP P60 protein
S101444_01068	COG0583	DNA-binding transcription factor activity
S101444_01069	COG0372	Belongs to the citrate synthase family
S101444_01070	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_01071	COG0531	amino acid
S101444_01072	COG0733	neurotransmitter:sodium symporter activity
S101444_01073	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101444_01074	COG0456	acetyltransferase
S101444_01077	COG1595	DNA-templated transcription, initiation
S101444_01078	COG0667	Aldo Keto reductase
S101444_01079	COG0204	Acyl-transferase
S101444_01080	COG1253	flavin adenine dinucleotide binding
S101444_01081	COG0789	Transcriptional regulator
S101444_01082	COG0436	Aminotransferase
S101444_01083	COG1253	flavin adenine dinucleotide binding
S101444_01084	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101444_01085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101444_01086	COG0584	glycerophosphoryl diester phosphodiesterase
S101444_01088	COG0668	transmembrane transport
S101444_01089	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
S101444_01090	COG0726	polysaccharide deacetylase
S101444_01091	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101444_01092	COG1757	Na H antiporter
S101444_01093	COG0589	response to stress
S101444_01094	COG1132	(ABC) transporter
S101444_01095	COG1132	(ABC) transporter
S101444_01096	COG0702	epimerase
S101444_01099	COG0189	ligase activity
S101444_01100	COG0189	ligase activity
S101444_01101	COG4399	Belongs to the UPF0754 family
S101444_01102	COG3679	Belongs to the UPF0342 family
S101444_01103	COG4335	DNA alkylation repair
S101444_01104	COG0561	phosphatase activity
S101444_01105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101444_01106	COG0475	glutathione-regulated potassium exporter activity
S101444_01107	COG0490	domain, Protein
S101444_01109	COG1024	Enoyl-CoA hydratase
S101444_01111	COG4152	abc transporter atp-binding protein
S101444_01112	COG1668	transmembrane transport
S101444_01113	COG0420	3'-5' exonuclease activity
S101444_01114	COG4717	serine-type aminopeptidase activity
S101444_01115	COG3481	metal-dependent phosphohydrolase, HD sub domain
S101444_01117	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101444_01120	COG1846	Transcriptional regulator
S101444_01121	COG4980	gas vesicle protein
S101444_01124	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
S101444_01125	COG0537	adenosine 5'-monophosphoramidase activity
S101444_01126	COG1131	(ABC) transporter
S101444_01127	COG4473	ABC transporter
S101444_01129	COG1473	amidohydrolase
S101444_01130	COG3069	C4-dicarboxylate transmembrane transporter activity
S101444_01132	COG2329	Antibiotic biosynthesis monooxygenase
S101444_01133	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101444_01134	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
S101444_01137	COG1309	transcriptional regulator
S101444_01138	COG1511	domain protein
S101444_01139	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101444_01140	COG4377	Putative membrane peptidase family (DUF2324)
S101444_01142	COG1363	Peptidase, m42
S101444_01143	COG4405	Protein conserved in bacteria
S101444_01144	COG1301	dicarboxylic acid transport
S101444_01145	COG1234	tRNA 3'-trailer cleavage
S101444_01146	COG0095	Lipoate-protein ligase
S101444_01147	COG0702	epimerase
S101444_01148	COG0318	PFAM AMP-dependent synthetase and ligase
S101444_01150	COG0501	Belongs to the peptidase M48B family
S101444_01152	COG0456	acetyltransferase
S101444_01153	COG0604	alcohol dehydrogenase
S101444_01154	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
S101444_01155	COG0406	alpha-ribazole phosphatase activity
S101444_01156	COG0183	Belongs to the thiolase family
S101444_01157	COG0318	PFAM AMP-dependent synthetase and ligase
S101444_01158	COG1268	BioY protein
S101444_01159	COG0840	transmembrane signaling receptor activity
S101444_01160	COG0723	plastoquinol--plastocyanin reductase activity
S101444_01160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101444_01161	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_01163	COG4903	ComK protein
S101444_01164	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_01166	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101444_01169	COG0398	Pfam SNARE associated Golgi protein
S101444_01170	COG0681	Belongs to the peptidase S26 family
S101444_01171	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101444_01172	COG1846	Transcriptional regulator
S101444_01175	COG0738	Major facilitator superfamily
S101444_01176	COG0673	inositol 2-dehydrogenase activity
S101444_01177	COG0561	phosphatase activity
S101444_01178	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101444_01179	COG1609	Transcriptional regulator
S101444_01180	COG3180	Ammonia monooxygenase
S101444_01181	COG2814	Major facilitator Superfamily
S101444_01181	COG0477	Major facilitator Superfamily
S101444_01182	COG4533	DNA binding
S101444_01183	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
S101444_01184	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
S101444_01185	COG1074	ATP-dependent DNA helicase activity
S101444_01186	COG0420	3'-5' exonuclease activity
S101444_01187	COG0419	ATPase involved in DNA repair
S101444_01188	COG1403	HNH endonuclease
S101444_01196	COG5337	Spore coat protein CotH
S101444_01197	COG0179	Fumarylacetoacetate (FAA) hydrolase
S101444_01199	COG1404	Belongs to the peptidase S8 family
S101444_01201	COG0367	asparagine synthase
S101444_01202	COG2318	DinB family
S101444_01203	COG1562	ergosterol biosynthetic process
S101444_01204	COG0534	Mate efflux family protein
S101444_01205	COG2207	Transcriptional regulator
S101444_01205	COG1917	Cupin 2, conserved barrel domain protein
S101444_01206	COG1609	Transcriptional regulator
S101444_01207	COG0673	inositol 2-dehydrogenase activity
S101444_01208	COG2318	DinB family
S101444_01209	COG1279	arginine transmembrane transporter activity
S101444_01210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101444_01211	COG1357	PFAM Pentapeptide repeats (8 copies)
S101444_01212	COG2267	carboxylic ester hydrolase activity
S101444_01213	COG0529	Catalyzes the synthesis of activated sulfate
S101444_01214	COG2046	Belongs to the sulfate adenylyltransferase family
S101444_01215	COG0175	sulfate reduction
S101444_01216	COG2045	Belongs to the ComB family
S101444_01217	COG1809	phosphosulfolactate synthase activity
S101444_01218	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101444_01219	COG4948	Mandelate Racemase Muconate Lactonizing
S101444_01220	COG2814	Major facilitator Superfamily
S101444_01221	COG0454	-acetyltransferase
S101444_01222	COG2153	protein acetylation
S101444_01223	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
S101444_01223	COG0646	methionine synthase
S101444_01224	COG1666	GTP binding
S101444_01225	COG2996	Protein conserved in bacteria
S101444_01229	COG1695	Transcriptional regulator
S101444_01232	COG3227	Zinc metalloprotease (Elastase)
S101444_01233	COG1307	EDD domain protein, DegV family
S101444_01234	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101444_01238	COG0561	phosphatase activity
S101444_01239	COG1073	alpha beta
S101444_01240	COG2151	metal-sulfur cluster biosynthetic enzyme
S101444_01242	COG0277	FAD linked oxidase domain protein
S101444_01243	COG2271	Major facilitator Superfamily
S101444_01244	COG2271	Major facilitator Superfamily
S101444_01245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
S101444_01248	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101444_01249	COG0505	Belongs to the CarA family
S101444_01250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101444_01251	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
S101444_01254	COG2267	carboxylic ester hydrolase activity
S101444_01256	COG1744	ABC transporter substrate-binding protein PnrA-like
S101444_01259	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101444_01260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101444_01261	COG5504	Zn-dependent protease
S101444_01262	COG0444	Belongs to the ABC transporter superfamily
S101444_01263	COG4608	Belongs to the ABC transporter superfamily
S101444_01265	COG0601	transmembrane transport
S101444_01266	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101444_01268	COG0180	Tryptophanyl-tRNA synthetase
S101444_01269	COG4166	transmembrane transport
S101444_01270	COG0601	transmembrane transport
S101444_01271	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101444_01272	COG0444	Belongs to the ABC transporter superfamily
S101444_01273	COG4608	Belongs to the ABC transporter superfamily
S101444_01274	COG2814	Major facilitator Superfamily
S101444_01275	COG0456	acetyltransferase
S101444_01276	COG1393	Belongs to the ArsC family
S101444_01277	COG0861	Integral membrane protein TerC family
S101444_01278	COG4862	establishment of competence for transformation
S101444_01279	COG4469	Competence protein
S101444_01280	COG1164	Oligoendopeptidase f
S101444_01283	COG2346	COG2346, Truncated hemoglobins
S101444_01284	COG0741	lytic transglycosylase activity
S101444_01285	COG4116	CYTH
S101444_01287	COG2357	RelA SpoT domain protein
S101444_01288	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101444_01289	COG0564	pseudouridine synthase activity
S101444_01290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
S101444_01291	COG0569	domain protein
S101444_01291	COG0475	glutathione-regulated potassium exporter activity
S101444_01292	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
S101444_01293	COG0352	thiamine-phosphate diphosphorylase activity
S101444_01294	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101444_01295	COG2104	thiamine diphosphate biosynthetic process
S101444_01296	COG2022	thiamine diphosphate biosynthetic process
S101444_01297	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101444_01298	COG0351	phosphomethylpyrimidine kinase
S101444_01299	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
S101444_01310	COG0210	DNA helicase
S101444_01312	COG2153	protein acetylation
S101444_01313	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S101444_01314	COG2382	esterase
S101444_01315	COG0626	cystathionine gamma-synthase activity
S101444_01316	COG0626	cystathionine gamma-synthase activity
S101444_01317	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_01318	COG5505	Protein of unknown function (DUF819)
S101444_01322	COG2856	Zn peptidase
S101444_01326	COG1396	sequence-specific DNA binding
S101444_01332	COG2801	Transposase and inactivated derivatives
S101444_01343	COG0457	Tetratricopeptide repeat
S101444_01344	COG5444	nuclease activity
S101444_01360	COG0457	Tetratricopeptide repeat
S101444_01361	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101444_01363	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_01363	COG3711	transcriptional antiterminator
S101444_01364	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101444_01364	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101444_01364	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_01365	COG1482	cell wall glycoprotein biosynthetic process
S101444_01367	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_01369	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S101444_01372	COG0109	protoheme IX farnesyltransferase activity
S101444_01374	COG0726	polysaccharide deacetylase
S101444_01377	COG5504	Zn-dependent protease
S101444_01378	COG2205	protein histidine kinase activity
S101444_01380	COG3383	formate dehydrogenase (NAD+) activity
S101444_01381	COG2427	Protein of unknown function (DUF1641)
S101444_01383	COG1051	belongs to the nudix hydrolase family
S101444_01385	COG2124	cytochrome p450
S101444_01386	COG1819	glycosyl
S101444_01388	COG1587	Uroporphyrinogen-III synthase
S101444_01389	COG0390	transport system, permease component
S101444_01390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101444_01391	COG0697	spore germination
S101444_01392	COG4297	protein containing double-stranded beta helix domain
S101444_01394	COG1252	NADH dehydrogenase
S101444_01395	COG1904	glucuronate isomerase
S101444_01396	COG2211	Major facilitator Superfamily
S101444_01397	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
S101444_01398	COG1063	alcohol dehydrogenase
S101444_01399	COG1312	Catalyzes the dehydration of D-mannonate
S101444_01400	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_01401	COG2271	Major facilitator Superfamily
S101444_01402	COG1609	Transcriptional regulator
S101444_01403	COG0246	Mannitol dehydrogenase
S101444_01404	COG2721	sulfolactate sulfo-lyase activity
S101444_01405	COG0730	response to heat
S101444_01406	COG2318	DinB family
S101444_01407	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S101444_01408	COG0457	Tetratricopeptide repeat
S101444_01410	COG2350	Protein conserved in bacteria
S101444_01411	COG1388	LysM domain
S101444_01411	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101444_01411	COG3409	Peptidoglycan-binding domain 1 protein
S101444_01413	COG4195	phage-related replication protein
S101444_01414	COG3546	catalase activity
S101444_01415	COG2856	Zn peptidase
S101444_01416	COG1396	sequence-specific DNA binding
S101444_01418	COG1522	sequence-specific DNA binding
S101444_01419	COG1484	DNA-dependent DNA replication
S101444_01424	COG1595	DNA-templated transcription, initiation
S101444_01425	COG3728	DNA packaging
S101444_01425	COG5484	DNA packaging
S101444_01426	COG1783	phage Terminase large subunit
S101444_01427	COG5518	Phage portal protein
S101444_01428	COG0338	D12 class N6 adenine-specific DNA methyltransferase
S101444_01429	COG4653	Phage capsid family
S101444_01437	COG3953	SLT domain
S101444_01437	COG5412	phage tail tape measure protein
S101444_01437	COG3953	SLT domain
S101444_01437	COG5412	phage tail tape measure protein
S101444_01437	COG3953	SLT domain
S101444_01437	COG5412	phage tail tape measure protein
S101444_01438	COG1652	LysM domain
S101444_01439	COG4193	domain, Protein
S101444_01441	COG3628	GPW Gp25 family protein
S101444_01442	COG3299	homolog of phage Mu protein gp47
S101444_01443	COG3778	Protein conserved in bacteria
S101444_01451	COG3409	Peptidoglycan-binding domain 1 protein
S101444_01451	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101444_01454	COG0306	phosphate transporter
S101444_01455	COG1392	Phosphate transport regulator
S101444_01456	COG0531	amino acid
S101444_01457	COG0346	lactoylglutathione lyase activity
S101444_01458	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101444_01459	COG0463	Glycosyl transferase, family 2
S101444_01461	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101444_01462	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101444_01463	COG2362	D-Aminopeptidase
S101444_01464	COG0601	transmembrane transport
S101444_01465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101444_01466	COG0444	Belongs to the ABC transporter superfamily
S101444_01467	COG4166	transmembrane transport
S101444_01469	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101444_01470	COG4948	Mandelate Racemase Muconate Lactonizing
S101444_01471	COG0791	NLP P60 protein
S101444_01472	COG4608	Belongs to the ABC transporter superfamily
S101444_01473	COG4608	Belongs to the ABC transporter superfamily
S101444_01474	COG2706	6-phosphogluconolactonase activity
S101444_01475	COG1834	amidinotransferase
S101444_01476	COG1607	acyl-coa hydrolase
S101444_01477	COG1017	nitric oxide dioxygenase activity
S101444_01477	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S101444_01479	COG2323	membrane
S101444_01480	COG2318	DinB family
S101444_01481	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_01482	COG2076	Multidrug Resistance protein
S101444_01483	COG2076	Multidrug Resistance protein
S101444_01484	COG0788	formyltetrahydrofolate deformylase activity
S101444_01485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101444_01486	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
S101444_01487	COG1764	response to oxidative stress
S101444_01488	COG1846	Transcriptional regulator
S101444_01489	COG1764	response to oxidative stress
S101444_01490	COG0590	tRNA wobble adenosine to inosine editing
S101444_01491	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101444_01492	COG1404	Belongs to the peptidase S8 family
S101444_01493	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_01494	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101444_01495	COG1122	ATPase activity
S101444_01496	COG4721	ABC-type cobalt transport system, permease component
S101444_01498	COG0745	RESPONSE REGULATOR receiver
S101444_01499	COG3850	Histidine kinase
S101444_01499	COG5002	protein histidine kinase activity
S101444_01500	COG3212	peptidase
S101444_01501	COG3212	peptidase
S101444_01504	COG2239	Acts as a magnesium transporter
S101444_01505	COG0789	Transcriptional regulator
S101444_01508	COG1846	Transcriptional regulator
S101444_01509	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101444_01510	COG0726	polysaccharide deacetylase
S101444_01511	COG1408	metallophosphoesterase
S101444_01513	COG0463	Glycosyl transferase, family 2
S101444_01514	COG3285	dna ligase
S101444_01514	COG1793	dna ligase
S101444_01515	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
S101444_01516	COG5001	Diguanylate cyclase
S101444_01516	COG3300	MHYT domain
S101444_01517	COG0586	Pfam SNARE associated Golgi protein
S101444_01518	COG0861	Integral membrane protein TerC family
S101444_01519	COG1191	sigma factor activity
S101444_01523	COG0501	Belongs to the peptidase M48B family
S101444_01524	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S101444_01527	COG3594	Acyltransferase
S101444_01528	COG5002	protein histidine kinase activity
S101444_01529	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101444_01531	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
S101444_01532	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
S101444_01533	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101444_01534	COG0436	Aminotransferase
S101444_01535	COG1850	ribulose-bisphosphate carboxylase activity
S101444_01536	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
S101444_01537	COG0235	Class ii aldolase
S101444_01538	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
S101444_01539	COG3339	Conserved Protein
S101444_01542	COG3852	Histidine kinase
S101444_01543	COG1846	Transcriptional regulator
S101444_01544	COG1360	Flagellar Motor Protein
S101444_01545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101444_01546	COG0542	response to heat
S101444_01547	COG3949	Membrane
S101444_01548	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
S101444_01549	COG0720	synthase
S101444_01550	COG0602	queuosine metabolic process
S101444_01551	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
S101444_01552	COG1733	regulation of RNA biosynthetic process
S101444_01553	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_01554	COG4974	Belongs to the 'phage' integrase family
S101444_01563	COG3858	chitin binding
S101444_01565	COG4873	Protein conserved in bacteria
S101444_01567	COG3773	Cell wall hydrolase
S101444_01568	COG2244	polysaccharide biosynthetic process
S101444_01569	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_01570	COG2217	Heavy metal translocating P-type atpase
S101444_01572	COG0006	proline dipeptidase activity
S101444_01574	COG1609	Transcriptional regulator
S101444_01576	COG3711	transcriptional antiterminator
S101444_01577	COG1263	PTS System
S101444_01577	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_01577	COG2190	(PTS) system
S101444_01578	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_01579	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
S101444_01581	COG1533	DNA photolyase activity
S101444_01582	COG0456	acetyltransferase
S101444_01583	COG0840	transmembrane signaling receptor activity
S101444_01584	COG2084	Dehydrogenase
S101444_01585	COG2340	Cysteine-rich secretory protein family
S101444_01586	COG0768	penicillin binding
S101444_01587	COG4191	Histidine kinase
S101444_01588	COG0436	Aminotransferase
S101444_01590	COG0784	Response regulator, receiver
S101444_01590	COG0835	chemotaxis
S101444_01592	COG2814	Major facilitator Superfamily
S101444_01593	COG1376	ErfK ybiS ycfS ynhG family protein
S101444_01594	COG1408	metallophosphoesterase
S101444_01595	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_01596	COG2200	EAL domain
S101444_01597	COG4703	Protein of unknown function (DUF1797)
S101444_01598	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
S101444_01600	COG0517	IMP dehydrogenase activity
S101444_01601	COG0583	DNA-binding transcription factor activity
S101444_01602	COG0716	FMN binding
S101444_01604	COG0716	FMN binding
S101444_01605	COG2171	N-acyltransferase activity
S101444_01606	COG1473	amidohydrolase
S101444_01608	COG0668	transmembrane transport
S101444_01609	COG0450	alkyl hydroperoxide reductase
S101444_01610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_01613	COG0746	molybdenum cofactor guanylyltransferase activity
S101444_01614	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101444_01615	COG0303	'Molybdopterin
S101444_01616	COG1763	Mo-molybdopterin cofactor biosynthetic process
S101444_01617	COG0314	molybdopterin synthase activity
S101444_01618	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
S101444_01619	COG1132	(ABC) transporter
S101444_01620	COG1132	(ABC) transporter
S101444_01622	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S101444_01623	COG1136	(ABC) transporter
S101444_01624	COG0577	efflux transmembrane transporter activity
S101444_01625	COG1349	DNA-binding transcription factor activity
S101444_01626	COG1105	Belongs to the carbohydrate kinase PfkB family
S101444_01627	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101444_01627	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101444_01627	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_01628	COG0681	Belongs to the peptidase S26 family
S101444_01630	COG0488	(ABC) transporter
S101444_01631	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101444_01632	COG2309	aminopeptidase activity
S101444_01634	COG1077	Cell shape determining protein MreB Mrl
S101444_01635	COG2002	toxin-antitoxin pair type II binding
S101444_01636	COG3852	Histidine kinase
S101444_01637	COG2105	PFAM AIG2 family protein
S101444_01637	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
S101444_01638	COG0569	domain protein
S101444_01639	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S101444_01640	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101444_01642	COG0561	phosphatase activity
S101444_01643	COG0242	peptide deformylase activity
S101444_01645	COG0497	DNA recombination
S101444_01646	COG0497	DNA recombination
S101444_01647	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101444_01648	COG0022	dehydrogenase e1 component
S101444_01649	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101444_01650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101444_01651	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_01653	COG1982	Orn Lys Arg decarboxylase major
S101444_01654	COG4476	Belongs to the UPF0223 family
S101444_01655	COG4493	Belongs to the UPF0637 family
S101444_01657	COG0483	inositol monophosphate 1-phosphatase activity
S101444_01659	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
S101444_01663	COG1595	DNA-templated transcription, initiation
S101444_01669	COG4896	Protein conserved in bacteria
S101444_01671	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
S101444_01672	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101444_01673	COG2066	Belongs to the glutaminase family
S101444_01674	COG4838	Belongs to the UPF0358 family
S101444_01675	COG0772	Belongs to the SEDS family
S101444_01676	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
S101444_01677	COG1612	heme a metabolic process
S101444_01678	COG0109	protoheme IX farnesyltransferase activity
S101444_01679	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101444_01679	COG2010	Cytochrome c
S101444_01680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101444_01681	COG1845	cytochrome c oxidase, subunit III
S101444_01682	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S101444_01683	COG3336	cytochrome c oxidase
S101444_01685	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
S101444_01686	COG2340	Cysteine-rich secretory protein family
S101444_01689	COG3679	Belongs to the UPF0342 family
S101444_01690	COG4471	UPF0298 protein
S101444_01691	COG0742	ribosomal rna small subunit methyltransferase
S101444_01692	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
S101444_01693	COG3314	Sporulation integral membrane protein YlbJ
S101444_01694	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101444_01695	COG3480	Lon protease (S16) C-terminal proteolytic domain
S101444_01696	COG1323	Belongs to the UPF0348 family
S101444_01698	COG1399	metal-binding, possibly nucleic acid-binding protein
S101444_01699	COG0333	Belongs to the bacterial ribosomal protein bL32 family
S101444_01701	COG0454	-acetyltransferase
S101444_01702	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101444_01703	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
S101444_01704	COG2001	Belongs to the MraZ family
S101444_01705	COG0275	rRNA processing
S101444_01706	COG4839	cell division protein FtsL
S101444_01708	COG0768	penicillin binding
S101444_01709	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
S101444_01710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S101444_01711	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S101444_01712	COG0772	Belongs to the SEDS family
S101444_01713	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101444_01714	COG0812	UDP-N-acetylmuramate dehydrogenase activity
S101444_01715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
S101444_01716	COG3879	Bacterial protein of unknown function (DUF881)
S101444_01717	COG3879	Bacterial protein of unknown function (DUF881)
S101444_01718	COG3856	small basic protein
S101444_01719	COG0849	cell division
S101444_01720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
S101444_01721	COG4412	M6 family metalloprotease domain protein
S101444_01721	COG1404	Belongs to the peptidase S8 family
S101444_01725	COG1191	sigma factor activity
S101444_01726	COG1191	sigma factor activity
S101444_01727	COG1119	ATPase activity
S101444_01728	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101444_01729	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101444_01730	COG1873	PFAM PRC-barrel domain
S101444_01732	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
S101444_01733	COG1799	cell septum assembly
S101444_01734	COG0762	integral membrane protein
S101444_01735	COG2302	S4 RNA-binding domain
S101444_01736	COG3599	regulation of cell shape
S101444_01737	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
S101444_01738	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101444_01739	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
S101444_01740	COG0564	pseudouridine synthase activity
S101444_01741	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
S101444_01742	COG2233	PERMEase
S101444_01743	COG0540	Belongs to the ATCase OTCase family
S101444_01744	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S101444_01745	COG0505	Belongs to the CarA family
S101444_01746	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101444_01747	COG0543	2 iron, 2 sulfur cluster binding
S101444_01748	COG0167	dihydroorotate dehydrogenase activity
S101444_01749	COG0284	orotidine-5'-phosphate decarboxylase activity
S101444_01750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
S101444_01751	COG0175	sulfate reduction
S101444_01752	COG0306	phosphate transporter
S101444_01753	COG2046	Belongs to the sulfate adenylyltransferase family
S101444_01754	COG0529	Catalyzes the synthesis of activated sulfate
S101444_01755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101444_01756	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
S101444_01757	COG1648	precorrin-2 dehydrogenase activity
S101444_01759	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S101444_01760	COG1561	YicC-like family, N-terminal region
S101444_01761	COG2052	Domain of unknown function (DUF370)
S101444_01762	COG0194	GDP metabolic process
S101444_01763	COG1758	RNA polymerase activity
S101444_01764	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101444_01765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101444_01766	COG0242	peptide deformylase activity
S101444_01767	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
S101444_01768	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S101444_01768	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
S101444_01769	COG0820	rRNA (adenine-C2-)-methyltransferase activity
S101444_01770	COG0631	protein serine/threonine phosphatase activity
S101444_01771	COG0515	serine threonine protein kinase
S101444_01771	COG2815	serine threonine protein kinase
S101444_01772	COG1162	GTPase activity
S101444_01773	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S101444_01774	COG1564	THIamine pyrophosphokinase
S101444_01775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
S101444_01776	COG1302	Protein conserved in bacteria
S101444_01777	COG1461	Dihydroxyacetone kinase
S101444_01778	COG1760	l-serine dehydratase
S101444_01779	COG1760	l-serine dehydratase
S101444_01780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
S101444_01781	COG2050	protein possibly involved in aromatic compounds catabolism
S101444_01781	COG1349	DNA-binding transcription factor activity
S101444_01782	COG0416	fatty acid biosynthetic process
S101444_01783	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S101444_01784	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_01785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101444_01786	COG0571	ribonuclease III activity
S101444_01787	COG1196	nuclear chromosome segregation
S101444_01788	COG0552	protein localization to endoplasmic reticulum
S101444_01790	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
S101444_01791	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
S101444_01792	COG0228	four-way junction DNA binding
S101444_01793	COG1837	Belongs to the UPF0109 family
S101444_01795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
S101444_01796	COG0336	Belongs to the RNA methyltransferase TrmD family
S101444_01797	COG0335	large ribosomal subunit rRNA binding
S101444_01798	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101444_01799	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
S101444_01801	COG2257	FlhB HrpN YscU SpaS Family
S101444_01802	COG0045	succinate-CoA ligase (ADP-forming) activity
S101444_01803	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
S101444_01804	COG0758	DNA mediated transformation
S101444_01805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101444_01806	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
S101444_01807	COG4974	Belongs to the 'phage' integrase family
S101444_01808	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
S101444_01809	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
S101444_01810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S101444_01811	COG1815	bacterial-type flagellum-dependent cell motility
S101444_01812	COG1558	bacterial-type flagellum-dependent cell motility
S101444_01813	COG1677	Flagellar hook-basal body complex protein FliE
S101444_01814	COG1766	The M ring may be actively involved in energy transduction
S101444_01815	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101444_01816	COG1317	bacterial-type flagellum organization
S101444_01817	COG1157	protein secretion by the type III secretion system
S101444_01818	COG2882	bacterial-type flagellum organization
S101444_01819	COG3334	PFAM MgtE intracellular
S101444_01820	COG3144	bacterial-type flagellum assembly
S101444_01821	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
S101444_01822	COG4786	Flagellar basal body rod
S101444_01823	COG1580	Controls the rotational direction of flagella during chemotaxis
S101444_01824	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101444_01825	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101444_01825	COG1776	CheC inhibitor of MCP methylation
S101444_01826	COG2201	protein-glutamate methylesterase activity
S101444_01827	COG3190	flagellar
S101444_01828	COG1338	Plays a role in the flagellum-specific transport system
S101444_01829	COG1987	bacterial-type flagellum assembly
S101444_01830	COG1684	flagellar biosynthetic protein fliR
S101444_01831	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101444_01832	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101444_01833	COG1419	protein localization to endoplasmic reticulum
S101444_01834	COG0455	bacterial-type flagellum organization
S101444_01835	COG2201	protein-glutamate methylesterase activity
S101444_01836	COG2198	Histidine kinase
S101444_01836	COG0643	Histidine kinase
S101444_01837	COG0835	chemotaxis
S101444_01838	COG1776	CheC inhibitor of MCP methylation
S101444_01839	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
S101444_01840	COG1191	sigma factor activity
S101444_01842	COG0052	Belongs to the universal ribosomal protein uS2 family
S101444_01843	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
S101444_01844	COG0528	UMP kinase activity
S101444_01845	COG0233	cytoplasmic translational termination
S101444_01846	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
S101444_01847	COG4589	Belongs to the CDS family
S101444_01848	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
S101444_01849	COG0750	zinc metalloprotease
S101444_01850	COG0442	prolyl-tRNA aminoacylation
S101444_01851	COG2176	DNA-directed DNA polymerase activity
S101444_01852	COG0779	Required for maturation of 30S ribosomal subunits
S101444_01853	COG0195	Participates in both transcription termination and antitermination
S101444_01854	COG2740	Nucleic-acid-binding protein implicated in transcription termination
S101444_01855	COG1358	cellular component organization or biogenesis
S101444_01856	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
S101444_01857	COG1550	Protein conserved in bacteria
S101444_01858	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
S101444_01859	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
S101444_01860	COG0196	riboflavin kinase activity
S101444_01861	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
S101444_01862	COG1185	polyribonucleotide nucleotidyltransferase activity
S101444_01863	COG0726	polysaccharide deacetylase
S101444_01864	COG0612	Peptidase, M16
S101444_01865	COG1873	PFAM PRC-barrel domain
S101444_01866	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101444_01867	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101444_01868	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
S101444_01869	COG0527	aspartate kinase activity
S101444_01870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
S101444_01871	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101444_01872	COG0740	serine-type endopeptidase activity
S101444_01874	COG1674	ftsk spoiiie
S101444_01874	COG4980	gas vesicle protein
S101444_01875	COG2188	Transcriptional regulator
S101444_01876	COG2814	Major facilitator Superfamily
S101444_01877	COG0612	Peptidase, M16
S101444_01878	COG0612	Peptidase, M16
S101444_01879	COG0300	oxidoreductase activity
S101444_01882	COG1426	Protein conserved in bacteria
S101444_01883	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
S101444_01884	COG1546	Belongs to the CinA family
S101444_01884	COG1058	Belongs to the CinA family
S101444_01885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
S101444_01886	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101444_01887	COG1418	mRNA catabolic process
S101444_01888	COG1692	metallophosphoesterase
S101444_01889	COG2359	stage V sporulation protein S
S101444_01890	COG1063	alcohol dehydrogenase
S101444_01891	COG0156	8-amino-7-oxononanoate synthase activity
S101444_01892	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S101444_01893	COG4550	Control of competence regulator ComK, YlbF/YmcA
S101444_01895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
S101444_01896	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
S101444_01902	COG0582	viral genome integration into host DNA
S101444_01912	COG3226	Transcriptional regulator
S101444_01914	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101444_01915	COG1404	Belongs to the peptidase S8 family
S101444_01916	COG4195	phage-related replication protein
S101444_01917	COG1764	response to oxidative stress
S101444_01918	COG2076	Multidrug Resistance protein
S101444_01919	COG2076	Multidrug Resistance protein
S101444_01922	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
S101444_01923	COG1923	regulation of RNA biosynthetic process
S101444_01926	COG1780	Probably involved in ribonucleotide reductase function
S101444_01927	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101444_01928	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101444_01929	COG4112	unkown
S101444_01930	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101444_01931	COG0464	growth
S101444_01932	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
S101444_01933	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
S101444_01934	COG0789	Transcriptional regulator
S101444_01935	COG0174	glutamine synthetase
S101444_01939	COG4282	regulation of fungal-type cell wall biogenesis
S101444_01942	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_01946	COG3655	Transcriptional regulator
S101444_01950	COG0135	phosphoribosylanthranilate isomerase activity
S101444_01951	COG2211	Major facilitator Superfamily
S101444_01952	COG3507	Belongs to the glycosyl hydrolase 43 family
S101444_01953	COG1940	carbohydrate kinase activity
S101444_01954	COG2115	Belongs to the xylose isomerase family
S101444_01955	COG1070	Carbohydrate kinase
S101444_01956	COG1525	nuclease
S101444_01957	COG2814	Major facilitator Superfamily
S101444_01958	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101444_01960	COG0756	dUTP diphosphatase activity
S101444_01969	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101444_01971	COG3832	glyoxalase III activity
S101444_01974	COG0697	spore germination
S101444_01975	COG0697	spore germination
S101444_01982	COG4195	phage-related replication protein
S101444_01984	COG0346	lactoylglutathione lyase activity
S101444_01985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
S101444_01986	COG1388	LysM domain
S101444_01987	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101444_01988	COG4224	UPF0291 protein
S101444_01989	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
S101444_01991	COG3763	UPF0154 protein
S101444_01993	COG0785	Cytochrome C biogenesis protein
S101444_01994	COG2201	protein-glutamate methylesterase activity
S101444_01995	COG4846	Membrane protein involved in cytochrome C biogenesis
S101444_01997	COG0071	Belongs to the small heat shock protein (HSP20) family
S101444_02000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
S101444_02001	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_02005	COG0824	Thioesterase
S101444_02007	COG4841	protein insertion into membrane
S101444_02008	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
S101444_02009	COG1832	CoA-binding protein
S101444_02010	COG0187	DNA topoisomerase II activity
S101444_02011	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101444_02014	COG1115	amino acid carrier protein
S101444_02015	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
S101444_02017	COG5520	Belongs to the glycosyl hydrolase 30 family
S101444_02018	COG3507	Belongs to the glycosyl hydrolase 43 family
S101444_02019	COG3507	Belongs to the glycosyl hydrolase 43 family
S101444_02020	COG2246	polysaccharide biosynthetic process
S101444_02021	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101444_02022	COG0586	Pfam SNARE associated Golgi protein
S101444_02023	COG2404	hydrolase activity, acting on ester bonds
S101444_02024	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101444_02025	COG1024	Enoyl-CoA hydratase
S101444_02026	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S101444_02027	COG0511	ligase activity, forming carbon-carbon bonds
S101444_02028	COG0439	Biotin carboxylase
S101444_02029	COG0318	PFAM AMP-dependent synthetase and ligase
S101444_02030	COG1960	acyl-CoA dehydrogenase activity
S101444_02031	COG1649	PFAM Uncharacterised BCR, COG1649
S101444_02033	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101444_02033	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101444_02034	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101444_02035	COG2027	D-alanyl-D-alanine carboxypeptidase
S101444_02036	COG2017	converts alpha-aldose to the beta-anomer
S101444_02037	COG0534	Mate efflux family protein
S101444_02040	COG0582	viral genome integration into host DNA
S101444_02041	COG0166	Belongs to the GPI family
S101444_02042	COG0405	Gamma-glutamyltransferase
S101444_02043	COG0583	DNA-binding transcription factor activity
S101444_02044	COG0604	alcohol dehydrogenase
S101444_02045	COG0493	'glutamate synthase
S101444_02046	COG0067	glutamate synthase
S101444_02046	COG0069	glutamate synthase activity
S101444_02046	COG0070	glutamate synthase
S101444_02047	COG0583	DNA-binding transcription factor activity
S101444_02048	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101444_02049	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101444_02051	COG0300	oxidoreductase activity
S101444_02052	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101444_02054	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_02055	COG2814	Major facilitator Superfamily
S101444_02056	COG1070	Carbohydrate kinase
S101444_02057	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S101444_02058	COG0243	molybdopterin cofactor binding
S101444_02060	COG2814	Major facilitator Superfamily
S101444_02061	COG0673	inositol 2-dehydrogenase activity
S101444_02062	COG1082	Xylose isomerase domain protein TIM barrel
S101444_02063	COG1609	Transcriptional regulator
S101444_02067	COG0840	transmembrane signaling receptor activity
S101444_02067	COG5278	phosphoserine phosphatase activity
S101444_02068	COG2368	4-hydroxyphenylacetate
S101444_02069	COG4305	rare lipoprotein A
S101444_02070	COG4305	rare lipoprotein A
S101444_02071	COG3619	membrane
S101444_02072	COG3866	Pectate lyase
S101444_02073	COG2135	peptidase activity
S101444_02076	COG2140	Oxalate decarboxylase
S101444_02080	COG2720	vancomycin resistance protein
S101444_02082	COG3655	Transcriptional regulator
S101444_02083	COG3739	integral membrane protein
S101444_02084	COG0583	DNA-binding transcription factor activity
S101444_02085	COG0697	spore germination
S101444_02087	COG0693	protein deglycase activity
S101444_02088	COG2367	Beta-lactamase
S101444_02091	COG3848	Pyruvate phosphate dikinase
S101444_02091	COG0574	Belongs to the PEP-utilizing enzyme family
S101444_02092	COG0574	Belongs to the PEP-utilizing enzyme family
S101444_02092	COG3848	Pyruvate phosphate dikinase
S101444_02093	COG0726	polysaccharide deacetylase
S101444_02094	COG2314	TM2 domain
S101444_02107	COG3655	Transcriptional regulator
S101444_02115	COG0457	Tetratricopeptide repeat
S101444_02117	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_02120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101444_02121	COG2226	methyltransferase
S101444_02122	COG2211	Major facilitator Superfamily
S101444_02123	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101444_02127	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_02128	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101444_02132	COG5444	nuclease activity
S101444_02133	COG4282	regulation of fungal-type cell wall biogenesis
S101444_02134	COG1231	oxidoreductase activity
S101444_02135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101444_02136	COG0662	Cupin 2, conserved barrel domain protein
S101444_02136	COG2207	Transcriptional regulator
S101444_02137	COG0456	acetyltransferase
S101444_02138	COG1309	transcriptional regulator
S101444_02139	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101444_02140	COG3708	Transcriptional regulator
S101444_02141	COG2378	regulation of single-species biofilm formation
S101444_02143	COG0640	Transcriptional regulator
S101444_02144	COG0741	lytic transglycosylase activity
S101444_02145	COG2322	membrane
S101444_02148	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101444_02149	COG3239	Fatty acid desaturase
S101444_02150	COG4585	Histidine kinase
S101444_02151	COG2197	response regulator
S101444_02153	COG3584	3D domain protein
S101444_02153	COG1388	LysM domain
S101444_02154	COG0514	ATP-dependent DNA helicase (RecQ)
S101444_02155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101444_02156	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101444_02159	COG0071	Belongs to the small heat shock protein (HSP20) family
S101444_02164	COG1012	belongs to the aldehyde dehydrogenase family
S101444_02165	COG1657	PFAM Prenyltransferase squalene oxidase
S101444_02166	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101444_02167	COG0733	neurotransmitter:sodium symporter activity
S101444_02168	COG0385	Bile acid
S101444_02169	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101444_02170	COG0567	Dehydrogenase, E1 component
S101444_02171	COG4548	von Willebrand factor, type A
S101444_02172	COG0714	Associated with various cellular activities
S101444_02173	COG2032	superoxide dismutase activity
S101444_02174	COG0791	NLP P60 protein
S101444_02174	COG1388	LysM domain
S101444_02175	COG1819	glycosyl
S101444_02176	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101444_02178	COG0534	Mate efflux family protein
S101444_02179	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_02180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101444_02181	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101444_02183	COG2962	Rard protein
S101444_02186	COG2610	gluconate transmembrane transporter activity
S101444_02187	COG2610	gluconate transmembrane transporter activity
S101444_02188	COG1942	4-Oxalocrotonate Tautomerase
S101444_02189	COG1733	regulation of RNA biosynthetic process
S101444_02190	COG0778	Nitroreductase
S101444_02191	COG0400	carboxylic ester hydrolase activity
S101444_02192	COG0346	lactoylglutathione lyase activity
S101444_02194	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101444_02195	COG3409	Peptidoglycan-binding domain 1 protein
S101444_02195	COG0793	Belongs to the peptidase S41A family
S101444_02196	COG2226	methyltransferase
S101444_02198	COG1876	peptidase activity
S101444_02199	COG0813	purine-nucleoside phosphorylase activity
S101444_02202	COG0671	phosphoesterase, PA-phosphatase related
S101444_02206	COG4479	Belongs to the UPF0346 family
S101444_02208	COG1509	lysine 2,3-aminomutase activity
S101444_02209	COG0456	acetyltransferase
S101444_02210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101444_02211	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101444_02212	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101444_02213	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101444_02215	COG0456	acetyltransferase
S101444_02216	COG0463	Glycosyl transferase, family 2
S101444_02219	COG4641	Protein conserved in bacteria
S101444_02220	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
S101444_02221	COG1086	Polysaccharide biosynthesis protein
S101444_02222	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
S101444_02223	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
S101444_02224	COG1846	Transcriptional regulator
S101444_02225	COG0534	Mate efflux family protein
S101444_02227	COG4698	Protein conserved in bacteria
S101444_02228	COG2755	lipolytic protein G-D-S-L family
S101444_02229	COG1999	signal sequence binding
S101444_02231	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101444_02232	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101444_02233	COG1272	protein, Hemolysin III
S101444_02234	COG0204	Acyl-transferase
S101444_02235	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101444_02236	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S101444_02238	COG2521	methyltransferase
S101444_02238	COG2136	Putative SAM-dependent methyltransferase
S101444_02240	COG0129	dihydroxy-acid dehydratase activity
S101444_02241	COG1413	lyase activity
S101444_02242	COG1418	mRNA catabolic process
S101444_02243	COG0386	Belongs to the glutathione peroxidase family
S101444_02244	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
S101444_02245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101444_02246	COG1278	Cold shock
S101444_02250	COG0328	RNA-DNA hybrid ribonuclease activity
S101444_02251	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
S101444_02252	COG0328	RNA-DNA hybrid ribonuclease activity
S101444_02254	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101444_02257	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101444_02259	COG1755	Isoprenylcysteine carboxyl methyltransferase
S101444_02260	COG3424	synthase
S101444_02261	COG2233	PERMEase
S101444_02262	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101444_02263	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
S101444_02265	COG0800	Aldolase
S101444_02266	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101444_02267	COG1609	Transcriptional regulator
S101444_02268	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
S101444_02269	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_02270	COG1199	ATP-dependent helicase activity
S101444_02272	COG0116	Belongs to the methyltransferase superfamily
S101444_02274	COG4474	Belongs to the UPF0398 family
S101444_02275	COG3359	exonuclease
S101444_02276	COG1111	helicase
S101444_02276	COG1205	dead DEAH box helicase
S101444_02277	COG2190	(PTS) system
S101444_02278	COG0071	Belongs to the small heat shock protein (HSP20) family
S101444_02285	COG3331	DNA recombination
S101444_02286	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101444_02286	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101444_02288	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
S101444_02289	COG3935	DnaD domain protein
S101444_02290	COG0017	Asparaginyl-tRNA synthetase
S101444_02291	COG0436	Aminotransferase
S101444_02292	COG5353	protein conserved in bacteria
S101444_02294	COG1199	ATP-dependent helicase activity
S101444_02294	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
S101444_02295	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
S101444_02296	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
S101444_02297	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
S101444_02298	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
S101444_02298	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
S101444_02299	COG0617	tRNA 3'-terminal CCA addition
S101444_02300	COG0438	transferase activity, transferring glycosyl groups
S101444_02301	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101444_02302	COG1803	Methylglyoxal synthase
S101444_02303	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
S101444_02304	COG1694	Mazg nucleotide pyrophosphohydrolase
S101444_02305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101444_02307	COG4347	Protein of unknown function (DUF1405)
S101444_02308	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101444_02308	COG2010	Cytochrome c
S101444_02309	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101444_02310	COG0723	plastoquinol--plastocyanin reductase activity
S101444_02312	COG5582	Belongs to the UPF0302 family
S101444_02313	COG0457	Tetratricopeptide repeat
S101444_02314	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
S101444_02315	COG0287	Prephenate dehydrogenase
S101444_02317	COG0159	tryptophan synthase activity
S101444_02318	COG0133	tryptophan synthase activity
S101444_02319	COG0135	phosphoribosylanthranilate isomerase activity
S101444_02321	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
S101444_02322	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101444_02323	COG4401	Chorismate mutase type I
S101444_02324	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
S101444_02325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
S101444_02326	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
S101444_02327	COG0105	UTP biosynthetic process
S101444_02328	COG0142	geranyltranstransferase activity
S101444_02329	COG2226	methyltransferase
S101444_02330	COG0142	geranyltranstransferase activity
S101444_02332	COG0302	gtp cyclohydrolase
S101444_02333	COG0776	regulation of translation
S101444_02334	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101444_02337	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
S101444_02338	COG1160	GTP binding
S101444_02343	COG1304	FMN binding
S101444_02344	COG0539	negative regulation of cytoplasmic translation
S101444_02345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
S101444_02347	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
S101444_02348	COG2959	enzyme of heme biosynthesis
S101444_02349	COG3773	Cell wall hydrolase
S101444_02349	COG3409	Peptidoglycan-binding domain 1 protein
S101444_02350	COG2339	peptidase activity
S101444_02351	COG0492	ferredoxin-NADP+ reductase activity
S101444_02352	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101444_02353	COG4862	establishment of competence for transformation
S101444_02354	COG1408	metallophosphoesterase
S101444_02356	COG1388	LysM domain
S101444_02357	COG1266	CAAX protease self-immunity
S101444_02358	COG0514	ATP-dependent DNA helicase (RecQ)
S101444_02359	COG4955	Helix-turn-helix domain
S101444_02360	COG1141	Ferredoxin
S101444_02361	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
S101444_02362	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S101444_02363	COG0710	3-dehydroquinate dehydratase activity
S101444_02365	COG1595	DNA-templated transcription, initiation
S101444_02366	COG5002	protein histidine kinase activity
S101444_02367	COG0745	RESPONSE REGULATOR receiver
S101444_02368	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101444_02369	COG1333	cytochrome c biogenesis protein
S101444_02370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_02371	COG1187	pseudouridine synthase activity
S101444_02372	COG0700	Nucleoside recognition
S101444_02373	COG2715	membrane protein required for spore maturation
S101444_02374	COG1686	Belongs to the peptidase S11 family
S101444_02376	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
S101444_02377	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
S101444_02378	COG1547	Domain of unknown function (DUF309)
S101444_02379	COG0456	acetyltransferase
S101444_02380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
S101444_02381	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101444_02381	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
S101444_02382	COG0307	riboflavin synthase, alpha
S101444_02383	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101444_02383	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101444_02385	COG0681	Belongs to the peptidase S26 family
S101444_02386	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
S101444_02388	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101444_02389	COG2433	Pfam Transposase IS66
S101444_02395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101444_02396	COG4086	secreted protein
S101444_02397	COG0019	diaminopimelate decarboxylase activity
S101444_02398	COG0697	spore germination
S101444_02401	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101444_02405	COG1191	sigma factor activity
S101444_02406	COG2172	sigma factor antagonist activity
S101444_02407	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_02408	COG1686	Belongs to the peptidase S11 family
S101444_02409	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
S101444_02410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
S101444_02411	COG4974	Belongs to the 'phage' integrase family
S101444_02413	COG0735	belongs to the Fur family
S101444_02414	COG1300	Membrane
S101444_02416	COG0281	malic enzyme
S101444_02417	COG1757	Na H antiporter
S101444_02418	COG1027	Aspartate ammonia-lyase
S101444_02419	COG0252	asparaginase activity
S101444_02420	COG1396	sequence-specific DNA binding
S101444_02421	COG1379	DNA repair
S101444_02422	COG0494	nUDIX hydrolase
S101444_02424	COG0667	Aldo Keto reductase
S101444_02426	COG1073	alpha beta
S101444_02428	COG4918	Iron-sulphur cluster biosynthesis
S101444_02429	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
S101444_02429	COG0456	acetyltransferase
S101444_02430	COG2329	Antibiotic biosynthesis monooxygenase
S101444_02431	COG0456	acetyltransferase
S101444_02433	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101444_02435	COG2211	Major facilitator Superfamily
S101444_02436	COG2211	Major facilitator Superfamily
S101444_02438	COG0346	lactoylglutathione lyase activity
S101444_02439	COG1072	(Pantothenic acid kinase))
S101444_02440	COG3048	D-serine ammonia-lyase activity
S101444_02441	COG0300	oxidoreductase activity
S101444_02442	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101444_02443	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101444_02444	COG4187	Peptidase family M20/M25/M40
S101444_02445	COG1902	pentaerythritol trinitrate reductase activity
S101444_02446	COG0596	Alpha beta hydrolase
S101444_02448	COG1234	tRNA 3'-trailer cleavage
S101444_02449	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
S101444_02450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S101444_02451	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S101444_02453	COG0706	membrane insertase activity
S101444_02454	COG3361	conserved protein (COG2071)
S101444_02455	COG2195	Cleaves the N-terminal amino acid of tripeptides
S101444_02456	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101444_02457	COG0346	lactoylglutathione lyase activity
S101444_02459	COG1376	ErfK ybiS ycfS ynhG family protein
S101444_02460	COG4129	membrane
S101444_02461	COG1126	abc transporter atp-binding protein
S101444_02462	COG0765	amino acid transport
S101444_02463	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101444_02465	COG1597	lipid kinase activity
S101444_02466	COG2814	Major facilitator Superfamily
S101444_02467	COG4978	Transcriptional regulator
S101444_02467	COG0789	Transcriptional regulator
S101444_02468	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101444_02469	COG0022	dehydrogenase e1 component
S101444_02470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101444_02471	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101444_02472	COG3426	butyrate kinase activity
S101444_02473	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101444_02474	COG0280	phosphate acetyltransferase
S101444_02475	COG3290	protein histidine kinase activity
S101444_02475	COG3829	transcription factor binding
S101444_02477	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
S101444_02478	COG2079	MmgE PrpD family protein
S101444_02479	COG0372	Belongs to the citrate synthase family
S101444_02480	COG1960	acyl-CoA dehydrogenase activity
S101444_02481	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101444_02482	COG0183	Belongs to the thiolase family
S101444_02483	COG0584	glycerophosphoryl diester phosphodiesterase
S101444_02484	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101444_02487	COG1902	pentaerythritol trinitrate reductase activity
S101444_02489	COG0745	RESPONSE REGULATOR receiver
S101444_02490	COG0750	zinc metalloprotease
S101444_02491	COG0497	DNA recombination
S101444_02492	COG1438	arginine binding
S101444_02493	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
S101444_02494	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
S101444_02495	COG0142	geranyltranstransferase activity
S101444_02496	COG1722	exodeoxyribonuclease VII activity
S101444_02497	COG1570	exodeoxyribonuclease VII activity
S101444_02498	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
S101444_02499	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S101444_02500	COG1302	Protein conserved in bacteria
S101444_02501	COG0439	Biotin carboxylase
S101444_02502	COG0511	ligase activity, forming carbon-carbon bonds
S101444_02510	COG3854	ATPases associated with a variety of cellular activities
S101444_02512	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
S101444_02513	COG0006	proline dipeptidase activity
S101444_02514	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
S101444_02516	COG3872	metal-dependent enzyme
S101444_02518	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101444_02519	COG1321	iron dependent repressor
S101444_02520	COG0095	Lipoate-protein ligase
S101444_02521	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101444_02522	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
S101444_02523	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
S101444_02524	COG0404	The glycine cleavage system catalyzes the degradation of glycine
S101444_02525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101444_02528	COG1396	sequence-specific DNA binding
S101444_02530	COG0681	Belongs to the peptidase S26 family
S101444_02535	COG4940	Competence protein ComGF
S101444_02537	COG4970	Tfp pilus assembly protein FimT
S101444_02538	COG4537	Required for transformation and DNA binding
S101444_02539	COG1459	type II secretion system
S101444_02540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
S101444_02541	COG0517	IMP dehydrogenase activity
S101444_02542	COG0598	Magnesium transport protein CorA
S101444_02543	COG1253	flavin adenine dinucleotide binding
S101444_02544	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_02546	COG1393	Belongs to the ArsC family
S101444_02548	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101444_02550	COG0011	TIGRFAM Protein of
S101444_02552	COG2866	Carboxypeptidase
S101444_02553	COG1368	sulfuric ester hydrolase activity
S101444_02554	COG1940	carbohydrate kinase activity
S101444_02555	COG4483	Protein conserved in bacteria
S101444_02556	COG0457	Tetratricopeptide repeat
S101444_02556	COG0705	Rhomboid family
S101444_02558	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
S101444_02559	COG0267	Belongs to the bacterial ribosomal protein bL33 family
S101444_02560	COG0438	transferase activity, transferring glycosyl groups
S101444_02563	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101444_02564	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101444_02565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101444_02566	COG0581	inorganic phosphate transmembrane transporter activity
S101444_02567	COG0573	inorganic phosphate transmembrane transporter activity
S101444_02568	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
S101444_02570	COG0477	Major facilitator Superfamily
S101444_02571	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101444_02572	COG2839	Protein conserved in bacteria
S101444_02573	COG5521	maltodextrose utilization protein MalA
S101444_02574	COG1388	LysM domain
S101444_02575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
S101444_02576	COG4709	membrane
S101444_02577	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
S101444_02578	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
S101444_02579	COG0735	belongs to the Fur family
S101444_02580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101444_02582	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
S101444_02583	COG0513	Belongs to the DEAD box helicase family
S101444_02585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
S101444_02586	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
S101444_02587	COG2384	SAM-dependent methyltransferase
S101444_02588	COG2010	Cytochrome c
S101444_02589	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
S101444_02590	COG0358	DNA primase activity
S101444_02591	COG1671	Belongs to the UPF0178 family
S101444_02592	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
S101444_02593	COG0517	IMP dehydrogenase activity
S101444_02594	COG0751	glycine-tRNA ligase activity
S101444_02595	COG0752	glycyl-tRNA synthetase alpha subunit
S101444_02596	COG1381	Involved in DNA repair and RecF pathway recombination
S101444_02598	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
S101444_02599	COG0295	cytidine deaminase activity
S101444_02600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
S101444_02601	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
S101444_02602	COG1480	7TM receptor with intracellular HD hydrolase
S101444_02604	COG1702	phosphate starvation-inducible protein PhoH
S101444_02605	COG0561	phosphatase activity
S101444_02608	COG4864	UPF0365 protein
S101444_02609	COG1030	water channel activity
S101444_02610	COG1610	YqeY-like protein
S101444_02611	COG0828	Belongs to the bacterial ribosomal protein bS21 family
S101444_02612	COG1283	sodium-dependent phosphate transmembrane transporter activity
S101444_02613	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S101444_02614	COG1385	rRNA (uridine-N3-)-methyltransferase activity
S101444_02615	COG2264	protein methyltransferase activity
S101444_02616	COG0484	heat shock protein binding
S101444_02617	COG0484	heat shock protein binding
S101444_02618	COG0443	Heat shock 70 kDa protein
S101444_02619	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
S101444_02620	COG1420	regulation of RNA biosynthetic process
S101444_02621	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101444_02622	COG0481	GTPase activity
S101444_02624	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101444_02625	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
S101444_02626	COG0268	Binds directly to 16S ribosomal RNA
S101444_02627	COG1466	dna polymerase III delta subunit
S101444_02629	COG2333	competence protein COMEC
S101444_02629	COG0658	competence protein
S101444_02630	COG2131	deaminase
S101444_02631	COG1555	photosystem II stabilization
S101444_02631	COG1596	polysaccharide export
S101444_02632	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101444_02633	COG2226	methyltransferase
S101444_02634	COG0799	negative regulation of ribosome biogenesis
S101444_02635	COG1713	HD superfamily hydrolase involved in NAD metabolism
S101444_02636	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
S101444_02637	COG1534	Rna-binding protein
S101444_02638	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S101444_02639	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101444_02640	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
S101444_02642	COG2755	lipolytic protein G-D-S-L family
S101444_02643	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101444_02643	COG3409	Peptidoglycan-binding domain 1 protein
S101444_02644	COG0398	Pfam SNARE associated Golgi protein
S101444_02645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
S101444_02647	COG3209	COG3209 Rhs family protein
S101444_02649	COG0114	fumarate hydratase activity
S101444_02650	COG0583	DNA-binding transcription factor activity
S101444_02653	COG0457	Tetratricopeptide repeat
S101444_02654	COG5444	nuclease activity
S101444_02655	COG5444	nuclease activity
S101444_02675	COG4978	Transcriptional regulator
S101444_02675	COG0789	Transcriptional regulator
S101444_02676	COG2814	Major facilitator Superfamily
S101444_02677	COG0456	acetyltransferase
S101444_02678	COG1253	flavin adenine dinucleotide binding
S101444_02680	COG0697	spore germination
S101444_02681	COG0583	DNA-binding transcription factor activity
S101444_02682	COG2072	flavoprotein involved in K transport
S101444_02683	COG1230	cation diffusion facilitator family transporter
S101444_02685	COG1114	Component of the transport system for branched-chain amino acids
S101444_02686	COG1687	branched-chain amino acid
S101444_02687	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
S101444_02688	COG1522	sequence-specific DNA binding
S101444_02689	COG2732	(Barnase) inhibitor
S101444_02690	COG2124	cytochrome p450
S101444_02692	COG1335	isochorismatase
S101444_02695	COG2318	DinB family
S101444_02697	COG2070	2-Nitropropane dioxygenase
S101444_02698	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
S101444_02701	COG3443	Belongs to the bacterial solute-binding protein 9 family
S101444_02702	COG1595	DNA-templated transcription, initiation
S101444_02703	COG0667	Aldo Keto reductase
S101444_02704	COG2851	Citrate transporter
S101444_02705	COG0583	DNA-binding transcription factor activity
S101444_02706	COG2828	Protein conserved in bacteria
S101444_02707	COG3409	Peptidoglycan-binding domain 1 protein
S101444_02708	COG5566	PFAM Mor transcription activator
S101444_02709	COG0596	Alpha beta hydrolase
S101444_02710	COG4991	sh3 domain protein
S101444_02711	COG4991	sh3 domain protein
S101444_02712	COG0346	lactoylglutathione lyase activity
S101444_02714	COG5577	PFAM Coat F domain
S101444_02715	COG1063	alcohol dehydrogenase
S101444_02717	COG5577	PFAM Coat F domain
S101444_02718	COG0789	Transcriptional regulator
S101444_02720	COG1064	alcohol dehydrogenase
S101444_02721	COG0693	protein deglycase activity
S101444_02722	COG1621	beta-fructofuranosidase activity
S101444_02723	COG3716	PTS system mannose fructose sorbose family IID component
S101444_02724	COG3715	PTS system
S101444_02725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_02726	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_02727	COG3933	PFAM sigma-54 factor interaction domain-containing protein
S101444_02727	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101444_02728	COG1113	amino acid transport
S101444_02729	COG1280	lysine exporter protein (LysE YggA)
S101444_02730	COG1378	Sugar-specific transcriptional regulator TrmB
S101444_02731	COG1595	DNA-templated transcription, initiation
S101444_02733	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
S101444_02733	COG2755	lipolytic protein G-D-S-L family
S101444_02735	COG2124	cytochrome p450
S101444_02735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101444_02736	COG1309	transcriptional regulator
S101444_02737	COG2226	methyltransferase
S101444_02740	COG2116	formate transmembrane transporter activity
S101444_02741	COG5609	conserved protein (DUF2294)
S101444_02742	COG3383	formate dehydrogenase (NAD+) activity
S101444_02743	COG2427	Protein of unknown function (DUF1641)
S101444_02745	COG0626	cystathionine gamma-synthase activity
S101444_02746	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101444_02747	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
S101444_02748	COG2226	methyltransferase
S101444_02751	COG0768	penicillin binding
S101444_02752	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
S101444_02753	COG0572	uridine kinase
S101444_02757	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101444_02758	COG3906	Belongs to the UPF0473 family
S101444_02759	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
S101444_02760	COG4472	Bacterial protein of unknown function (DUF965)
S101444_02761	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
S101444_02762	COG0628	permease
S101444_02763	COG1126	abc transporter atp-binding protein
S101444_02764	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101444_02765	COG0765	amino acid transport
S101444_02766	COG0765	amino acid transport
S101444_02769	COG3881	PFAM PRC-barrel domain
S101444_02770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
S101444_02771	COG0457	Tetratricopeptide repeat
S101444_02772	COG0482	sulfurtransferase activity
S101444_02773	COG1104	cysteine desulfurase activity
S101444_02774	COG1959	2 iron, 2 sulfur cluster binding
S101444_02775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
S101444_02776	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
S101444_02777	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
S101444_02778	COG0124	histidyl-tRNA synthetase
S101444_02780	COG3103	Sh3 type 3 domain protein
S101444_02780	COG4991	sh3 domain protein
S101444_02780	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101444_02781	COG1490	D-aminoacyl-tRNA deacylase activity
S101444_02782	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S101444_02783	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101444_02784	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
S101444_02784	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
S101444_02785	COG5416	Lipopolysaccharide assembly protein A domain
S101444_02786	COG0490	domain, Protein
S101444_02787	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101444_02787	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101444_02789	COG2244	polysaccharide biosynthetic process
S101444_02790	COG2323	membrane
S101444_02792	COG1862	Preprotein translocase
S101444_02793	COG0343	queuine tRNA-ribosyltransferase activity
S101444_02794	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
S101444_02796	COG2255	four-way junction helicase activity
S101444_02797	COG0632	four-way junction helicase activity
S101444_02799	COG2814	Major facilitator Superfamily
S101444_02800	COG0673	inositol 2-dehydrogenase activity
S101444_02801	COG2112	serine threonine protein kinase
S101444_02805	COG1115	amino acid carrier protein
S101444_02806	COG0217	transcriptional regulatory protein
S101444_02808	COG1388	LysM domain
S101444_02809	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
S101444_02810	COG0157	Belongs to the NadC ModD family
S101444_02811	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
S101444_02812	COG1104	cysteine desulfurase activity
S101444_02813	COG1827	regulation of RNA biosynthetic process
S101444_02814	COG0077	Prephenate dehydratase
S101444_02815	COG4492	Belongs to the UPF0735 family
S101444_02816	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
S101444_02817	COG3290	protein histidine kinase activity
S101444_02818	COG0211	Belongs to the bacterial ribosomal protein bL27 family
S101444_02819	COG2868	ribosomal protein
S101444_02820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
S101444_02821	COG1994	Peptidase M50
S101444_02822	COG0739	heme binding
S101444_02823	COG2894	cell division
S101444_02824	COG0850	regulation of cytokinetic process
S101444_02825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
S101444_02826	COG1792	Involved in formation and maintenance of cell shape
S101444_02827	COG1077	Cell shape determining protein MreB Mrl
S101444_02828	COG2003	Belongs to the UPF0758 family
S101444_02829	COG0424	maF-like protein
S101444_02831	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
S101444_02832	COG0285	dihydrofolate synthase activity
S101444_02833	COG0525	valine-tRNA ligase activity
S101444_02835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101444_02836	COG1388	LysM domain
S101444_02837	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
S101444_02838	COG0113	porphobilinogen synthase activity
S101444_02839	COG1587	Uroporphyrinogen-III synthase
S101444_02840	COG0181	hydroxymethylbilane synthase activity
S101444_02841	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101444_02842	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
S101444_02844	COG0218	Necessary for normal cell division and for the maintenance of normal septation
S101444_02845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
S101444_02846	COG1067	ATP-dependent peptidase activity
S101444_02846	COG0470	DNA polymerase III
S101444_02847	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
S101444_02848	COG0544	peptidyl-prolyl cis-trans isomerase activity
S101444_02849	COG0457	Tetratricopeptide repeat
S101444_02849	COG1477	protein flavinylation
S101444_02850	COG0066	3-isopropylmalate dehydratase activity
S101444_02851	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
S101444_02852	COG0473	3-isopropylmalate dehydrogenase activity
S101444_02853	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S101444_02854	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
S101444_02855	COG0440	acetolactate synthase activity
S101444_02856	COG0028	Belongs to the TPP enzyme family
S101444_02858	COG0454	-acetyltransferase
S101444_02859	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
S101444_02861	COG0622	Phosphoesterase
S101444_02862	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
S101444_02863	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
S101444_02864	COG5401	PFAM Sporulation and spore germination
S101444_02865	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
S101444_02866	COG1846	Transcriptional regulator
S101444_02867	COG2197	response regulator
S101444_02868	COG0824	Thioesterase
S101444_02869	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
S101444_02870	COG1053	succinate dehydrogenase
S101444_02871	COG2009	succinate dehydrogenase
S101444_02872	COG1719	4-vinyl reductase, 4VR
S101444_02873	COG0527	aspartate kinase activity
S101444_02874	COG0322	excinuclease ABC activity
S101444_02875	COG3118	belongs to the thioredoxin family
S101444_02876	COG3534	alpha-L-arabinofuranosidase
S101444_02878	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
S101444_02879	COG2086	electron transfer activity
S101444_02880	COG1024	Enoyl-CoA hydratase
S101444_02881	COG1309	transcriptional regulator
S101444_02882	COG0318	PFAM AMP-dependent synthetase and ligase
S101444_02883	COG3766	membrane
S101444_02884	COG1193	negative regulation of DNA recombination
S101444_02885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101444_02885	COG1796	DNA polymerase
S101444_02886	COG1286	toxin biosynthetic process
S101444_02887	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
S101444_02888	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
S101444_02889	COG0072	phenylalanine-tRNA ligase activity
S101444_02889	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101444_02890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
S101444_02891	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101444_02893	COG3835	regulator
S101444_02894	COG0277	FAD linked oxidase domain protein
S101444_02895	COG0247	lactate metabolic process
S101444_02896	COG0346	lactoylglutathione lyase activity
S101444_02897	COG1966	Carbon starvation protein
S101444_02898	COG3534	alpha-L-arabinofuranosidase
S101444_02899	COG0395	ABC-type sugar transport system, permease component
S101444_02900	COG1175	transmembrane transport
S101444_02901	COG1653	transport
S101444_02902	COG0371	Dehydrogenase
S101444_02903	COG0647	UMP catabolic process
S101444_02904	COG0235	Class ii aldolase
S101444_02905	COG1069	ribulokinase activity
S101444_02906	COG2160	L-arabinose isomerase activity
S101444_02907	COG3507	Belongs to the glycosyl hydrolase 43 family
S101444_02908	COG1363	Peptidase, m42
S101444_02910	COG3326	Membrane
S101444_02911	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
S101444_02912	COG0291	Belongs to the bacterial ribosomal protein bL35 family
S101444_02913	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
S101444_02915	COG1346	cytolysis
S101444_02916	COG1380	Effector of murein hydrolase LrgA
S101444_02917	COG3279	Response regulator of the LytR AlgR family
S101444_02918	COG3275	phosphorelay sensor kinase activity
S101444_02920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S101444_02923	COG0398	Pfam SNARE associated Golgi protein
S101444_02924	COG1484	DNA-dependent DNA replication
S101444_02925	COG3611	Membrane attachment protein
S101444_02926	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
S101444_02927	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
S101444_02928	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101444_02929	COG1733	regulation of RNA biosynthetic process
S101444_02930	COG1733	regulation of RNA biosynthetic process
S101444_02931	COG2814	Major facilitator Superfamily
S101444_02932	COG0656	L-ascorbic acid biosynthetic process
S101444_02933	COG0237	dephospho-CoA kinase activity
S101444_02934	COG1971	Probably functions as a manganese efflux pump
S101444_02935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
S101444_02936	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101444_02936	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101444_02937	COG5002	protein histidine kinase activity
S101444_02938	COG0745	RESPONSE REGULATOR receiver
S101444_02939	COG0039	L-malate dehydrogenase activity
S101444_02940	COG0538	isocitrate dehydrogenase activity
S101444_02941	COG0372	Belongs to the citrate synthase family
S101444_02942	COG2707	UPF0756 membrane protein
S101444_02943	COG0628	permease
S101444_02944	COG0628	permease
S101444_02945	COG3030	protein affecting phage T7 exclusion by the F plasmid
S101444_02946	COG0469	pyruvate kinase activity
S101444_02947	COG0205	6-phosphofructokinase activity
S101444_02948	COG0825	malonyl-CoA metabolic process
S101444_02949	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
S101444_02950	COG0281	malic enzyme
S101444_02951	COG0587	DNA-directed DNA polymerase activity
S101444_02955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
S101444_02957	COG4109	DRTGG domain
S101444_02958	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
S101444_02959	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_02961	COG0165	Argininosuccinate lyase
S101444_02962	COG0137	argininosuccinate synthase activity
S101444_02963	COG0521	Mo-molybdopterin cofactor biosynthetic process
S101444_02964	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
S101444_02966	COG0827	DNA restriction-modification system
S101444_02967	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
S101444_02968	COG3874	Sporulation protein YtfJ
S101444_02970	COG1714	RDD family
S101444_02971	COG0616	signal peptide processing
S101444_02972	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101444_02973	COG1574	metal-dependent hydrolase with the TIM-barrel fold
S101444_02974	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101444_02976	COG0301	tRNA thio-modification
S101444_02977	COG1104	cysteine desulfurase activity
S101444_02978	COG1114	Component of the transport system for branched-chain amino acids
S101444_02979	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
S101444_02980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101444_02981	COG1309	transcriptional regulator
S101444_02982	COG1956	GAF domain-containing protein
S101444_02983	COG2203	Gaf domain
S101444_02983	COG2199	diguanylate cyclase activity
S101444_02984	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
S101444_02986	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
S101444_02987	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101444_02988	COG0454	-acetyltransferase
S101444_02989	COG0517	IMP dehydrogenase activity
S101444_02990	COG0123	including yeast histone deacetylase and acetoin utilization protein
S101444_02991	COG1360	Flagellar Motor Protein
S101444_02992	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101444_02993	COG1609	Transcriptional regulator
S101444_02994	COG1605	Chorismate mutase
S101444_02994	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
S101444_02995	COG3118	belongs to the thioredoxin family
S101444_02996	COG4980	gas vesicle protein
S101444_02997	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101444_02998	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
S101444_02999	COG1674	ftsk spoiiie
S101444_03000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101444_03001	COG4848	Belongs to the UPF0354 family
S101444_03002	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_03004	COG1363	Peptidase, m42
S101444_03005	COG5584	Small secreted protein
S101444_03006	COG0281	malic enzyme
S101444_03007	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101444_03008	COG0220	tRNA (guanine-N7-)-methyltransferase activity
S101444_03010	COG0510	thiamine kinase activity
S101444_03011	COG1523	belongs to the glycosyl hydrolase 13 family
S101444_03012	COG1597	lipid kinase activity
S101444_03014	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S101444_03015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101444_03016	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101444_03017	COG2252	PERMEase
S101444_03018	COG4473	ABC transporter
S101444_03019	COG1131	(ABC) transporter
S101444_03020	COG1349	DNA-binding transcription factor activity
S101444_03021	COG1187	pseudouridine synthase activity
S101444_03022	COG2244	polysaccharide biosynthetic process
S101444_03023	COG2081	HI0933 family
S101444_03024	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
S101444_03026	COG5578	integral membrane protein
S101444_03027	COG0673	inositol 2-dehydrogenase activity
S101444_03028	COG1653	transport
S101444_03029	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
S101444_03030	COG4209	transmembrane transport
S101444_03031	COG2207	Transcriptional regulator
S101444_03032	COG1653	transport
S101444_03033	COG0395	ABC-type sugar transport system, permease component
S101444_03034	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101444_03035	COG2124	cytochrome p450
S101444_03036	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
S101444_03038	COG0156	8-amino-7-oxononanoate synthase activity
S101444_03039	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101444_03041	COG1073	alpha beta
S101444_03046	COG1486	melibiose metabolic process
S101444_03047	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101444_03048	COG0495	leucyl-tRNA aminoacylation
S101444_03050	COG1366	Belongs to the anti-sigma-factor antagonist family
S101444_03050	COG2202	Pas domain
S101444_03051	COG2814	Major facilitator Superfamily
S101444_03052	COG2433	Pfam Transposase IS66
S101444_03053	COG0577	efflux transmembrane transporter activity
S101444_03054	COG1136	(ABC) transporter
S101444_03055	COG2205	protein histidine kinase activity
S101444_03056	COG0745	RESPONSE REGULATOR receiver
S101444_03057	COG0577	efflux transmembrane transporter activity
S101444_03058	COG1136	(ABC) transporter
S101444_03061	COG1131	(ABC) transporter
S101444_03062	COG1725	Transcriptional regulator
S101444_03065	COG1242	4 iron, 4 sulfur cluster binding
S101444_03066	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
S101444_03068	COG2267	carboxylic ester hydrolase activity
S101444_03069	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
S101444_03070	COG1113	amino acid transport
S101444_03071	COG0367	asparagine synthase
S101444_03072	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
S101444_03073	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
S101444_03075	COG1506	peptidase
S101444_03076	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101444_03077	COG1116	anion transmembrane transporter activity
S101444_03078	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101444_03079	COG0494	nUDIX hydrolase
S101444_03080	COG4824	toxin secretion phage lysis holin
S101444_03081	COG0783	Belongs to the Dps family
S101444_03084	COG1854	S-ribosylhomocysteine lyase activity
S101444_03085	COG0288	reversible hydration of carbon dioxide
S101444_03086	COG0254	rRNA binding
S101444_03087	COG1271	oxidase subunit
S101444_03088	COG1294	oxidase, subunit
S101444_03090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101444_03091	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101444_03091	COG1321	iron dependent repressor
S101444_03092	COG1121	(ABC) transporter
S101444_03093	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101444_03094	COG4948	Mandelate Racemase Muconate Lactonizing
S101444_03095	COG0318	PFAM AMP-dependent synthetase and ligase
S101444_03096	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
S101444_03097	COG0596	Alpha beta hydrolase
S101444_03098	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
S101444_03099	COG1169	isochorismate synthase
S101444_03100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101444_03101	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101444_03102	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101444_03103	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101444_03104	COG0438	transferase activity, transferring glycosyl groups
S101444_03106	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101444_03107	COG0438	transferase activity, transferring glycosyl groups
S101444_03108	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101444_03109	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
S101444_03110	COG0058	SHG alpha-glucan phosphorylase activity
S101444_03111	COG0297	glycogen (starch) synthase activity
S101444_03112	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
S101444_03113	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
S101444_03114	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
S101444_03139	COG3859	Proton-coupled thiamine transporter YuaJ
S101444_03140	COG1247	-acetyltransferase
S101444_03141	COG2268	Band 7 protein
S101444_03142	COG1585	Membrane protein implicated in regulation of membrane protease activity
S101444_03143	COG2318	DinB family
S101444_03145	COG1454	alcohol dehydrogenase
S101444_03147	COG1510	regulation of RNA biosynthetic process
S101444_03149	COG0569	domain protein
S101444_03150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S101444_03151	COG4682	membrane
S101444_03152	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101444_03153	COG0477	Major facilitator Superfamily
S101444_03154	COG5553	Cysteine dioxygenase type I
S101444_03156	COG1968	undecaprenyl-diphosphatase activity
S101444_03157	COG0628	permease
S101444_03158	COG0673	inositol 2-dehydrogenase activity
S101444_03159	COG4806	L-rhamnose isomerase
S101444_03160	COG3254	rhamnose metabolic process
S101444_03161	COG1070	Carbohydrate kinase
S101444_03162	COG1349	DNA-binding transcription factor activity
S101444_03163	COG3347	Dehydrogenase
S101444_03163	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03164	COG0840	transmembrane signaling receptor activity
S101444_03165	COG0840	transmembrane signaling receptor activity
S101444_03166	COG0840	transmembrane signaling receptor activity
S101444_03167	COG0840	transmembrane signaling receptor activity
S101444_03170	COG0432	Pfam Uncharacterised protein family UPF0047
S101444_03171	COG0366	Alpha amylase catalytic
S101444_03172	COG1253	flavin adenine dinucleotide binding
S101444_03173	COG2738	Putative neutral zinc metallopeptidase
S101444_03176	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
S101444_03179	COG0166	Belongs to the GPI family
S101444_03180	COG1979	alcohol dehydrogenase
S101444_03181	COG1979	alcohol dehydrogenase
S101444_03182	COG2155	Conserved Protein
S101444_03183	COG1098	S1 RNA binding domain
S101444_03184	COG0436	Aminotransferase
S101444_03185	COG1522	sequence-specific DNA binding
S101444_03186	COG2267	carboxylic ester hydrolase activity
S101444_03188	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S101444_03189	COG2205	protein histidine kinase activity
S101444_03191	COG5018	Exonuclease
S101444_03193	COG2814	Major facilitator Superfamily
S101444_03194	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101444_03195	COG3011	Protein conserved in bacteria
S101444_03197	COG3290	protein histidine kinase activity
S101444_03198	COG4565	transcriptional regulatory protein
S101444_03203	COG3493	citrate carrier protein
S101444_03205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S101444_03205	COG2111	Na H antiporter
S101444_03206	COG2111	Na H antiporter
S101444_03207	COG1006	Multisubunit Na H antiporter MnhC subunit
S101444_03208	COG0651	ATP synthesis coupled electron transport
S101444_03209	COG1863	multisubunit Na H antiporter MnhE subunit
S101444_03210	COG2212	antiporter activity
S101444_03211	COG1320	monovalent cation:proton antiporter activity
S101444_03212	COG2050	protein possibly involved in aromatic compounds catabolism
S101444_03213	COG2197	response regulator
S101444_03214	COG4585	Histidine kinase
S101444_03216	COG0142	geranyltranstransferase activity
S101444_03220	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
S101444_03221	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
S101444_03222	COG1335	isochorismatase
S101444_03223	COG5506	Protein of unknown function (DUF1694)
S101444_03226	COG0628	permease
S101444_03228	COG1418	mRNA catabolic process
S101444_03229	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03231	COG1511	domain protein
S101444_03232	COG0433	COG0433 Predicted ATPase
S101444_03232	COG1674	ftsk spoiiie
S101444_03233	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101444_03234	COG5417	Belongs to the EsaB family
S101444_03235	COG4842	Belongs to the WXG100 family
S101444_03236	COG2508	Transcriptional regulator
S101444_03236	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S101444_03237	COG0686	Belongs to the AlaDH PNT family
S101444_03238	COG5634	Uncharacterized conserved protein (DUF2278)
S101444_03239	COG3251	PFAM MbtH domain protein
S101444_03240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101444_03241	COG1535	isochorismatase
S101444_03241	COG3433	isochorismatase activity
S101444_03242	COG1021	2,3-dihydroxybenzoate-AMP ligase
S101444_03243	COG1169	isochorismate synthase
S101444_03244	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03245	COG2819	hydrolase of the alpha beta superfamily
S101444_03246	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101444_03247	COG1268	BioY protein
S101444_03248	COG2056	Na+-H+ antiporter family
S101444_03249	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
S101444_03250	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
S101444_03251	COG3584	3D domain protein
S101444_03253	COG1252	NADH dehydrogenase
S101444_03254	COG0492	ferredoxin-NADP+ reductase activity
S101444_03256	COG0516	GMP reductase activity
S101444_03257	COG2808	Putative FMN-binding domain
S101444_03258	COG0456	acetyltransferase
S101444_03260	COG0316	Belongs to the HesB IscA family
S101444_03261	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
S101444_03262	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101444_03263	COG4844	belongs to the
S101444_03264	COG1252	NADH dehydrogenase
S101444_03265	COG4837	Protein of unknown function (DUF1462)
S101444_03266	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
S101444_03267	COG4946	Tricorn protease homolog
S101444_03267	COG1506	peptidase
S101444_03267	COG0823	Involved in the tonB-independent uptake of proteins
S101444_03268	COG0083	homoserine kinase activity
S101444_03269	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
S101444_03270	COG0460	homoserine dehydrogenase
S101444_03271	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101444_03272	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S101444_03273	COG0647	UMP catabolic process
S101444_03274	COG2445	Protein of unknown function DUF86
S101444_03275	COG4470	Protein conserved in bacteria
S101444_03277	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
S101444_03278	COG0739	heme binding
S101444_03280	COG3377	Domain of unknown function (DUF1805)
S101444_03281	COG0737	Belongs to the 5'-nucleotidase family
S101444_03282	COG0730	response to heat
S101444_03283	COG1801	Protein of unknown function DUF72
S101444_03285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S101444_03286	COG2508	Transcriptional regulator
S101444_03287	COG2233	PERMEase
S101444_03288	COG2233	PERMEase
S101444_03289	COG3195	allantoin biosynthetic process
S101444_03289	COG3648	Uricase
S101444_03290	COG2351	hydroxyisourate hydrolase activity
S101444_03292	COG2080	2 iron, 2 sulfur cluster binding
S101444_03293	COG1529	Aldehyde oxidase and xanthine dehydrogenase
S101444_03294	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
S101444_03295	COG2068	MobA-Related Protein
S101444_03296	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
S101444_03297	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
S101444_03298	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101444_03299	COG2356	endonuclease I
S101444_03300	COG3842	ATPase activity
S101444_03301	COG2188	Transcriptional regulator
S101444_03302	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101444_03303	COG0395	ABC-type sugar transport system, permease component
S101444_03304	COG1175	transmembrane transport
S101444_03305	COG1653	transport
S101444_03306	COG2222	sugar isomerase
S101444_03307	COG0322	excinuclease ABC activity
S101444_03308	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101444_03311	COG0346	lactoylglutathione lyase activity
S101444_03312	COG0640	Transcriptional regulator
S101444_03313	COG0719	Fe-S assembly protein
S101444_03314	COG0822	iron-sulfur transferase activity
S101444_03315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101444_03316	COG0719	Fe-S assembly protein
S101444_03317	COG0396	ATPase activity
S101444_03318	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S101444_03319	COG1464	Belongs to the NlpA lipoprotein family
S101444_03320	COG2011	ABC-type metal ion transport system permease component
S101444_03321	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
S101444_03323	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101444_03324	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101444_03326	COG0509	glycine decarboxylation via glycine cleavage system
S101444_03327	COG1393	Belongs to the ArsC family
S101444_03328	COG1960	acyl-CoA dehydrogenase activity
S101444_03329	COG0183	Belongs to the thiolase family
S101444_03330	COG1024	Enoyl-CoA hydratase
S101444_03330	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101444_03332	COG0506	proline dehydrogenase activity
S101444_03334	COG5577	PFAM Coat F domain
S101444_03335	COG1846	Transcriptional regulator
S101444_03336	COG0477	Major facilitator Superfamily
S101444_03337	COG1942	4-Oxalocrotonate Tautomerase
S101444_03338	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03339	COG0583	DNA-binding transcription factor activity
S101444_03341	COG1120	ATPase activity
S101444_03346	COG1131	(ABC) transporter
S101444_03354	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03355	COG0783	Belongs to the Dps family
S101444_03356	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101444_03357	COG0745	RESPONSE REGULATOR receiver
S101444_03358	COG2205	protein histidine kinase activity
S101444_03358	COG2770	Histidine kinase
S101444_03359	COG1309	transcriptional regulator
S101444_03360	COG0114	fumarate hydratase activity
S101444_03362	COG0697	spore germination
S101444_03363	COG0814	amino acid
S101444_03365	COG2197	response regulator
S101444_03366	COG4585	Histidine kinase
S101444_03367	COG4758	membrane
S101444_03368	COG3595	metallopeptidase activity
S101444_03369	COG1842	Phage shock protein A
S101444_03370	COG4758	membrane
S101444_03371	COG2814	Major facilitator Superfamily
S101444_03372	COG2096	Adenosyltransferase
S101444_03373	COG1120	ATPase activity
S101444_03374	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_03375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101444_03376	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03377	COG3386	PFAM SMP-30 Gluconolaconase
S101444_03378	COG2205	protein histidine kinase activity
S101444_03379	COG0745	RESPONSE REGULATOR receiver
S101444_03381	COG1191	sigma factor activity
S101444_03383	COG2140	Oxalate decarboxylase
S101444_03385	COG0577	efflux transmembrane transporter activity
S101444_03386	COG1136	(ABC) transporter
S101444_03387	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S101444_03388	COG1120	ATPase activity
S101444_03389	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_03390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101444_03391	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101444_03393	COG0531	amino acid
S101444_03395	COG1988	membrane-bound metal-dependent
S101444_03396	COG1368	sulfuric ester hydrolase activity
S101444_03397	COG1910	domain protein
S101444_03398	COG0725	ABC transporter, periplasmic molybdate-binding protein
S101444_03399	COG4149	molybdate abc transporter
S101444_03400	COG0656	L-ascorbic acid biosynthetic process
S101444_03402	COG0025	NhaP-type Na H and K H
S101444_03403	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101444_03404	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101444_03405	COG3973	AAA domain
S101444_03407	COG2860	membrane
S101444_03408	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
S101444_03409	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S101444_03410	COG2217	Heavy metal translocating P-type atpase
S101444_03411	COG2217	Heavy metal translocating P-type atpase
S101444_03412	COG2608	mercury ion transmembrane transporter activity
S101444_03413	COG1937	Protein conserved in bacteria
S101444_03414	COG0673	inositol 2-dehydrogenase activity
S101444_03415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101444_03416	COG1289	transmembrane transporter activity
S101444_03418	COG2076	Multidrug Resistance protein
S101444_03419	COG1309	transcriptional regulator
S101444_03420	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03421	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
S101444_03422	COG0557	exoribonuclease II activity
S101444_03423	COG1647	Serine aminopeptidase, S33
S101444_03424	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101444_03425	COG0596	Alpha beta hydrolase
S101444_03426	COG1476	TRANSCRIPTIONal
S101444_03427	COG1396	sequence-specific DNA binding
S101444_03428	COG1396	sequence-specific DNA binding
S101444_03429	COG1733	regulation of RNA biosynthetic process
S101444_03430	COG0840	transmembrane signaling receptor activity
S101444_03431	COG1174	glycine betaine transport
S101444_03432	COG1732	Glycine betaine
S101444_03433	COG1174	glycine betaine transport
S101444_03434	COG0517	IMP dehydrogenase activity
S101444_03434	COG1125	glycine betaine transport
S101444_03435	COG1510	regulation of RNA biosynthetic process
S101444_03436	COG1174	glycine betaine transport
S101444_03437	COG1732	Glycine betaine
S101444_03438	COG1174	glycine betaine transport
S101444_03439	COG0517	IMP dehydrogenase activity
S101444_03439	COG1125	glycine betaine transport
S101444_03440	COG1510	regulation of RNA biosynthetic process
S101444_03441	COG2095	MarC family integral membrane protein
S101444_03443	COG3064	Membrane
S101444_03444	COG4640	response to antibiotic
S101444_03445	COG0456	acetyltransferase
S101444_03446	COG0148	phosphopyruvate hydratase activity
S101444_03447	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
S101444_03448	COG0149	triose-phosphate isomerase activity
S101444_03449	COG0126	phosphoglycerate kinase activity
S101444_03450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101444_03451	COG2390	Transcriptional regulator
S101444_03452	COG2814	Major facilitator Superfamily
S101444_03453	COG1609	Transcriptional regulator
S101444_03454	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101444_03455	COG0583	DNA-binding transcription factor activity
S101444_03456	COG0697	spore germination
S101444_03457	COG1113	amino acid transport
S101444_03458	COG3858	chitin binding
S101444_03459	COG1556	Lactate utilization protein
S101444_03460	COG1139	Iron-sulfur cluster binding protein
S101444_03461	COG0247	lactate metabolic process
S101444_03464	COG2197	response regulator
S101444_03465	COG4585	Histidine kinase
S101444_03466	COG0842	Transport permease protein
S101444_03467	COG1131	(ABC) transporter
S101444_03469	COG0596	Alpha beta hydrolase
S101444_03470	COG2208	phosphoserine phosphatase activity
S101444_03471	COG3867	Arabinogalactan endo-beta-1,4-galactanase
S101444_03472	COG1874	Beta-galactosidase
S101444_03473	COG3833	ABC-type maltose transport systems, permease component
S101444_03474	COG1175	transmembrane transport
S101444_03475	COG2182	Extracellular solute-binding protein
S101444_03476	COG1609	Transcriptional regulator
S101444_03477	COG2186	Transcriptional regulator
S101444_03478	COG1620	l-lactate permease
S101444_03479	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S101444_03481	COG5039	Polysaccharide pyruvyl transferase
S101444_03482	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101444_03483	COG0110	maltose O-acetyltransferase activity
S101444_03484	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
S101444_03485	COG2244	polysaccharide biosynthetic process
S101444_03486	COG1216	Glycosyl transferase, family 2
S101444_03487	COG5039	Polysaccharide pyruvyl transferase
S101444_03488	COG1216	Glycosyl transferase, family 2
S101444_03490	COG0438	transferase activity, transferring glycosyl groups
S101444_03491	COG1215	transferase activity, transferring glycosyl groups
S101444_03492	COG0438	transferase activity, transferring glycosyl groups
S101444_03493	COG1086	Polysaccharide biosynthesis protein
S101444_03494	COG0489	protein tyrosine kinase activity
S101444_03495	COG3944	biosynthesis protein
S101444_03496	COG1396	sequence-specific DNA binding
S101444_03497	COG2272	Belongs to the type-B carboxylesterase lipase family
S101444_03499	COG3479	Phenolic acid decarboxylase
S101444_03501	COG1794	racemase activity, acting on amino acids and derivatives
S101444_03502	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101444_03503	COG1621	beta-fructofuranosidase activity
S101444_03504	COG1621	beta-fructofuranosidase activity
S101444_03505	COG0531	amino acid
S101444_03506	COG1309	transcriptional regulator
S101444_03507	COG2076	Multidrug Resistance protein
S101444_03508	COG2076	Multidrug Resistance protein
S101444_03511	COG0740	serine-type endopeptidase activity
S101444_03512	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101444_03513	COG0366	Alpha amylase catalytic
S101444_03514	COG1554	hydrolase, family 65, central catalytic
S101444_03515	COG5521	maltodextrose utilization protein MalA
S101444_03516	COG3833	ABC-type maltose transport systems, permease component
S101444_03517	COG1175	transmembrane transport
S101444_03518	COG2182	Extracellular solute-binding protein
S101444_03519	COG0366	Alpha amylase catalytic
S101444_03520	COG1609	Transcriptional regulator
S101444_03521	COG1611	Belongs to the LOG family
S101444_03522	COG1694	Mazg nucleotide pyrophosphohydrolase
S101444_03523	COG0659	secondary active sulfate transmembrane transporter activity
S101444_03524	COG0288	reversible hydration of carbon dioxide
S101444_03525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101444_03526	COG0577	efflux transmembrane transporter activity
S101444_03527	COG1136	(ABC) transporter
S101444_03528	COG5002	protein histidine kinase activity
S101444_03529	COG0745	RESPONSE REGULATOR receiver
S101444_03531	COG2162	N-hydroxyarylamine O-acetyltransferase activity
S101444_03532	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_03533	COG1481	regulation of sporulation
S101444_03534	COG0391	Required for morphogenesis under gluconeogenic growth conditions
S101444_03535	COG1660	Displays ATPase and GTPase activities
S101444_03536	COG1051	belongs to the nudix hydrolase family
S101444_03537	COG0492	ferredoxin-NADP+ reductase activity
S101444_03538	COG0791	NLP P60 protein
S101444_03538	COG3883	PFAM NLP P60 protein
S101444_03539	COG0791	NLP P60 protein
S101444_03539	COG3883	PFAM NLP P60 protein
S101444_03540	COG0457	Tetratricopeptide repeat
S101444_03541	COG1132	(ABC) transporter
S101444_03545	COG0140	phosphoribosyl-ATP diphosphatase activity
S101444_03545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
S101444_03546	COG0107	imidazoleglycerol-phosphate synthase activity
S101444_03547	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
S101444_03548	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
S101444_03549	COG0131	Imidazoleglycerol-phosphate dehydratase
S101444_03550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
S101444_03551	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
S101444_03552	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
S101444_03553	COG4990	cell redox homeostasis
S101444_03554	COG5297	Belongs to the glycosyl hydrolase family 6
S101444_03555	COG0110	maltose O-acetyltransferase activity
S101444_03556	COG0546	phosphoglycolate phosphatase activity
S101444_03557	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
S101444_03558	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
S101444_03559	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
S101444_03560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
S101444_03561	COG0363	glucosamine-6-phosphate deaminase activity
S101444_03563	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
S101444_03564	COG1846	Transcriptional regulator
S101444_03565	COG2124	cytochrome p450
S101444_03567	COG1846	Transcriptional regulator
S101444_03568	COG2814	Major facilitator Superfamily
S101444_03569	COG1950	PFAM Membrane protein of
S101444_03570	COG1983	PspC domain protein
S101444_03571	COG3595	metallopeptidase activity
S101444_03574	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101444_03575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
S101444_03576	COG0556	nucleotide-excision repair
S101444_03577	COG4897	Protein conserved in bacteria
S101444_03578	COG0574	Belongs to the PEP-utilizing enzyme family
S101444_03578	COG3848	Pyruvate phosphate dikinase
S101444_03579	COG1309	transcriptional regulator
S101444_03580	COG2814	Major facilitator Superfamily
S101444_03581	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101444_03583	COG0793	Belongs to the peptidase S41A family
S101444_03583	COG3409	Peptidoglycan-binding domain 1 protein
S101444_03584	COG2177	Part of the ABC transporter FtsEX involved in
S101444_03585	COG2884	Cell division ATP-binding protein ftsE
S101444_03586	COG2010	Cytochrome c
S101444_03587	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101444_03588	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
S101444_03589	COG0653	protein targeting
S101444_03590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
S101444_03593	COG1516	flagellar protein fliS
S101444_03594	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
S101444_03595	COG1334	flagellar protein FlaG
S101444_03596	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101444_03597	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
S101444_03598	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
S101444_03600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101444_03601	COG1256	bacterial-type flagellum assembly
S101444_03601	COG4786	Flagellar basal body rod
S101444_03602	COG3418	PFAM FlgN family protein
S101444_03603	COG2747	anti-sigma28 factor FlgM
S101444_03605	COG1040	competence protein
S101444_03607	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
S101444_03608	COG1307	EDD domain protein, DegV family
S101444_03609	COG2197	response regulator
S101444_03610	COG4585	Histidine kinase
S101444_03611	COG1739	Uncharacterized protein family UPF0029
S101444_03612	COG1316	TRANSCRIPTIONal
S101444_03619	COG1131	(ABC) transporter
S101444_03621	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S101444_03622	COG0438	transferase activity, transferring glycosyl groups
S101444_03623	COG1215	transferase activity, transferring glycosyl groups
S101444_03624	COG3206	protein involved in exopolysaccharide biosynthesis
S101444_03625	COG3307	-O-antigen
S101444_03627	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101444_03628	COG0297	glycogen (starch) synthase activity
S101444_03628	COG0438	transferase activity, transferring glycosyl groups
S101444_03629	COG2244	polysaccharide biosynthetic process
S101444_03631	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101444_03631	COG2247	cell wall binding repeat
S101444_03632	COG2385	sporulation resulting in formation of a cellular spore
S101444_03632	COG2247	cell wall binding repeat
S101444_03634	COG1316	TRANSCRIPTIONal
S101444_03635	COG1316	TRANSCRIPTIONal
S101444_03636	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
S101444_03637	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101444_03639	COG1134	teichoic acid transport
S101444_03640	COG1682	transport, permease protein
S101444_03643	COG0463	Glycosyl transferase, family 2
S101444_03643	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101444_03644	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101444_03645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
S101444_03646	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
S101444_03647	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101444_03648	COG4193	domain, Protein
S101444_03649	COG1482	cell wall glycoprotein biosynthetic process
S101444_03650	COG0697	spore germination
S101444_03651	COG0814	amino acid
S101444_03653	COG2814	Major facilitator Superfamily
S101444_03654	COG1316	TRANSCRIPTIONal
S101444_03655	COG0561	phosphatase activity
S101444_03656	COG2801	Transposase and inactivated derivatives
S101444_03658	COG0791	NLP P60 protein
S101444_03660	COG2843	Capsule synthesis protein
S101444_03662	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S101444_03663	COG1609	Transcriptional regulator
S101444_03664	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101444_03665	COG1869	D-ribose catabolic process
S101444_03666	COG1129	ABC transporter
S101444_03667	COG1172	Belongs to the binding-protein-dependent transport system permease family
S101444_03668	COG1879	ABC-type sugar transport system periplasmic component
S101444_03669	COG3103	Sh3 type 3 domain protein
S101444_03671	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101444_03672	COG3527	Alpha-acetolactate decarboxylase
S101444_03673	COG0028	Belongs to the TPP enzyme family
S101444_03674	COG0583	DNA-binding transcription factor activity
S101444_03675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101444_03678	COG5337	Spore coat protein CotH
S101444_03680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S101444_03682	COG0405	Gamma-glutamyltransferase
S101444_03683	COG1522	sequence-specific DNA binding
S101444_03684	COG2059	Chromate
S101444_03685	COG2059	Chromate
S101444_03687	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101444_03688	COG0583	DNA-binding transcription factor activity
S101444_03692	COG5444	nuclease activity
S101444_03695	COG5444	nuclease activity
S101444_03698	COG3878	Protein conserved in bacteria
S101444_03699	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101444_03700	COG4464	protein tyrosine phosphatase activity
S101444_03701	COG0489	protein tyrosine kinase activity
S101444_03702	COG3944	biosynthesis protein
S101444_03704	COG4715	Zinc finger, swim domain protein
S101444_03705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101444_03706	COG0561	phosphatase activity
S101444_03707	COG1349	DNA-binding transcription factor activity
S101444_03708	COG0629	single-stranded DNA binding
S101444_03711	COG3764	Sortase (surface protein transpeptidase)
S101444_03712	COG2972	Histidine kinase
S101444_03712	COG0745	RESPONSE REGULATOR receiver
S101444_03713	COG2972	Histidine kinase
S101444_03713	COG0745	RESPONSE REGULATOR receiver
S101444_03714	COG1970	mechanosensitive ion channel activity
S101444_03715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S101444_03716	COG0457	Tetratricopeptide repeat
S101444_03717	COG4786	Flagellar basal body rod
S101444_03718	COG4786	Flagellar basal body rod
S101444_03719	COG1077	Cell shape determining protein MreB Mrl
S101444_03720	COG1609	Transcriptional regulator
S101444_03721	COG1846	Transcriptional regulator
S101444_03722	COG2814	Major facilitator Superfamily
S101444_03723	COG3420	alginic acid biosynthetic process
S101444_03724	COG1953	Uracil, thiamine, allantoin
S101444_03725	COG0477	Major facilitator Superfamily
S101444_03726	COG1335	isochorismatase
S101444_03728	COG0004	ammonium transporteR
S101444_03729	COG0347	Belongs to the P(II) protein family
S101444_03730	COG0671	phosphoesterase, PA-phosphatase related
S101444_03732	COG0739	heme binding
S101444_03733	COG1247	-acetyltransferase
S101444_03735	COG2089	acid synthase
S101444_03737	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101444_03738	COG0789	Transcriptional regulator
S101444_03740	COG2910	NAD(P)H-binding
S101444_03741	COG1959	2 iron, 2 sulfur cluster binding
S101444_03742	COG0804	urea catabolic process
S101444_03743	COG0832	Belongs to the urease beta subunit family
S101444_03744	COG0831	urea catabolic process
S101444_03746	COG3237	CsbD-like
S101444_03747	COG1994	Peptidase M50
S101444_03748	COG0457	Tetratricopeptide repeat
S101444_03749	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
S101444_03750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
S101444_03752	COG2304	oxidoreductase activity
S101444_03753	COG2304	oxidoreductase activity
S101444_03754	COG2385	sporulation resulting in formation of a cellular spore
S101444_03755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101444_03757	COG4836	Membrane
S101444_03759	COG0355	proton-transporting ATP synthase activity, rotational mechanism
S101444_03760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
S101444_03761	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
S101444_03762	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
S101444_03763	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
S101444_03764	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
S101444_03765	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
S101444_03766	COG0356	it plays a direct role in the translocation of protons across the membrane
S101444_03768	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
S101444_03769	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
S101444_03770	COG4475	Protein of unknown function (DUF436)
S101444_03771	COG0698	ribose 5-phosphate isomerase
S101444_03772	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101444_03773	COG1971	Probably functions as a manganese efflux pump
S101444_03774	COG0009	L-threonylcarbamoyladenylate synthase
S101444_03775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
S101444_03779	COG2890	protein-(glutamine-N5) methyltransferase activity
S101444_03780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
S101444_03781	COG0346	lactoylglutathione lyase activity
S101444_03782	COG0789	Transcriptional regulator
S101444_03783	COG0679	Auxin Efflux Carrier
S101444_03784	COG0281	malic enzyme
S101444_03785	COG1435	thymidine kinase activity
S101444_03786	COG0254	rRNA binding
S101444_03787	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
S101444_03788	COG1494	fructose-1,6-bisphosphatase
S101444_03789	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101444_03790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
S101444_03791	COG0191	fructose-bisphosphate aldolase activity
S101444_03792	COG2204	response regulator
S101444_03793	COG4821	SIS domain
S101444_03794	COG2801	Transposase and inactivated derivatives
S101444_03796	COG0504	CTP synthase activity
S101444_03797	COG3343	RNA polymerase activity
S101444_03798	COG1960	acyl-CoA dehydrogenase activity
S101444_03799	COG0247	lactate metabolic process
S101444_03799	COG2181	nitrate reductase activity
S101444_03800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101444_03801	COG4294	response to UV
S101444_03803	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101444_03804	COG1132	(ABC) transporter
S101444_03805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101444_03806	COG2181	nitrate reductase activity
S101444_03807	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
S101444_03808	COG1140	nitrate reductase beta subunit
S101444_03809	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
S101444_03810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101444_03812	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101444_03813	COG2223	nitrite transmembrane transporter activity
S101444_03814	COG0018	arginyl-trna synthetase
S101444_03815	COG4506	Protein conserved in bacteria
S101444_03817	COG0535	radical SAM domain protein
S101444_03819	COG1131	(ABC) transporter
S101444_03820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S101444_03821	COG0612	Peptidase, M16
S101444_03822	COG0612	Peptidase, M16
S101444_03824	COG3391	amine dehydrogenase activity
S101444_03825	COG3391	amine dehydrogenase activity
S101444_03826	COG0457	Tetratricopeptide repeat
S101444_03828	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S101444_03829	COG0010	Belongs to the arginase family
S101444_03830	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
S101444_03831	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101444_03833	COG1994	Peptidase M50
S101444_03834	COG1942	4-Oxalocrotonate Tautomerase
S101444_03835	COG1846	Transcriptional regulator
S101444_03836	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S101444_03838	COG0477	Major facilitator Superfamily
S101444_03839	COG1959	2 iron, 2 sulfur cluster binding
S101444_03840	COG3465	dGTPase activity
S101444_03841	COG1078	dGTPase activity
S101444_03842	COG4844	belongs to the
S101444_03844	COG0697	spore germination
S101444_03845	COG0095	Lipoate-protein ligase
S101444_03846	COG0583	DNA-binding transcription factor activity
S101444_03847	COG0280	phosphate acetyltransferase
S101444_03849	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03850	COG0436	Aminotransferase
S101444_03851	COG2814	Major facilitator Superfamily
S101444_03852	COG0151	Belongs to the GarS family
S101444_03853	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03854	COG1917	Cupin 2, conserved barrel domain protein
S101444_03855	COG0077	Prephenate dehydratase
S101444_03856	COG2814	Major facilitator Superfamily
S101444_03857	COG0833	amino acid
S101444_03858	COG4187	Peptidase family M20/M25/M40
S101444_03859	COG1012	belongs to the aldehyde dehydrogenase family
S101444_03860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101444_03862	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
S101444_03863	COG1091	dTDP-4-dehydrorhamnose reductase activity
S101444_03864	COG1088	dTDP-glucose 4,6-dehydratase activity
S101444_03865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
S101444_03866	COG3980	spore coat polysaccharide biosynthesis protein
S101444_03867	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
S101444_03868	COG2089	acid synthase
S101444_03869	COG2089	acid synthase
S101444_03870	COG0456	acetyltransferase
S101444_03871	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101444_03872	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101444_03873	COG0463	Glycosyl transferase, family 2
S101444_03875	COG2363	Small membrane protein
S101444_03876	COG2233	PERMEase
S101444_03878	COG1012	belongs to the aldehyde dehydrogenase family
S101444_03879	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
S101444_03880	COG1216	Glycosyl transferase, family 2
S101444_03881	COG0351	phosphomethylpyrimidine kinase
S101444_03883	COG1621	beta-fructofuranosidase activity
S101444_03884	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_03884	COG1263	PTS System
S101444_03885	COG2116	formate transmembrane transporter activity
S101444_03886	COG3711	transcriptional antiterminator
S101444_03888	COG1404	Belongs to the peptidase S8 family
S101444_03889	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101444_03890	COG0778	Nitroreductase
S101444_03891	COG0772	Belongs to the SEDS family
S101444_03894	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S101444_03895	COG1845	cytochrome c oxidase, subunit III
S101444_03896	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101444_03897	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101444_03898	COG2261	transglycosylase associated protein
S101444_03899	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
S101444_03900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
S101444_03901	COG2246	polysaccharide biosynthetic process
S101444_03902	COG1309	transcriptional regulator
S101444_03904	COG3162	membrane
S101444_03905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101444_03906	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S101444_03907	COG2837	iron assimilation
S101444_03908	COG2822	iron ion transport
S101444_03909	COG0672	)-iron permease
S101444_03910	COG0352	thiamine-phosphate diphosphorylase activity
S101444_03911	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
S101444_03912	COG0583	DNA-binding transcription factor activity
S101444_03913	COG1380	Effector of murein hydrolase LrgA
S101444_03914	COG1346	cytolysis
S101444_03915	COG2814	Major facilitator Superfamily
S101444_03916	COG4895	conserved protein (DUF2196)
S101444_03917	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
S101444_03918	COG0346	lactoylglutathione lyase activity
S101444_03920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101444_03921	COG1404	Belongs to the peptidase S8 family
S101444_03922	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_03922	COG1263	PTS System
S101444_03923	COG3711	transcriptional antiterminator
S101444_03924	COG1442	glycosyl transferase family 8
S101444_03925	COG5522	Integral membrane protein (intg_mem_TP0381)
S101444_03926	COG1846	Transcriptional regulator
S101444_03927	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
S101444_03928	COG2234	aminopeptidase activity
S101444_03929	COG2357	RelA SpoT domain protein
S101444_03930	COG2801	Transposase and inactivated derivatives
S101444_03932	COG1575	Belongs to the MenA family. Type 1 subfamily
S101444_03934	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101444_03935	COG1696	Membrane protein involved in D-alanine export
S101444_03936	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101444_03937	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
S101444_03938	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S101444_03939	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101444_03940	COG1486	melibiose metabolic process
S101444_03941	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101444_03942	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101444_03943	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101444_03944	COG3711	transcriptional antiterminator
S101444_03944	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101444_03946	COG2094	Belongs to the DNA glycosylase MPG family
S101444_03947	COG0753	catalase activity
S101444_03948	COG2814	Major facilitator Superfamily
S101444_03949	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101444_03950	COG1131	(ABC) transporter
S101444_03954	COG1595	DNA-templated transcription, initiation
S101444_03955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101444_03956	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
S101444_03957	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
S101444_03958	COG4988	ABC transporter
S101444_03959	COG1294	oxidase, subunit
S101444_03960	COG1271	oxidase subunit
S101444_03961	COG3493	citrate carrier protein
S101444_03962	COG0501	Belongs to the peptidase M48B family
S101444_03964	COG0726	polysaccharide deacetylase
S101444_03965	COG3842	ATPase activity
S101444_03966	COG2508	Transcriptional regulator
S101444_03967	COG1012	belongs to the aldehyde dehydrogenase family
S101444_03968	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101444_03970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S101444_03972	COG4585	Histidine kinase
S101444_03973	COG2197	response regulator
S101444_03974	COG2195	Cleaves the N-terminal amino acid of tripeptides
S101444_03976	COG4894	glucomannan catabolic process
S101444_03977	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101444_03978	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101444_03979	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_03980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101444_03981	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101444_03982	COG2610	gluconate transmembrane transporter activity
S101444_03983	COG0500	methyltransferase
S101444_03984	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101444_03987	COG0753	catalase activity
S101444_03987	COG0693	protein deglycase activity
S101444_03988	COG2851	Citrate transporter
S101444_03989	COG2273	Hydrolase Family 16
S101444_03990	COG3711	transcriptional antiterminator
S101444_03992	COG2270	Major facilitator Superfamily
S101444_03993	COG0513	Belongs to the DEAD box helicase family
S101444_03994	COG2755	lipolytic protein G-D-S-L family
S101444_03994	COG3401	FG-GAP repeat protein
S101444_04019	COG0697	spore germination
S101444_04020	COG0589	response to stress
S101444_04021	COG2723	6-phospho-beta-galactosidase activity
S101444_04022	COG2190	(PTS) system
S101444_04022	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_04022	COG1263	PTS System
S101444_04024	COG5444	nuclease activity
S101444_04026	COG5444	nuclease activity
S101444_04029	COG3507	Belongs to the glycosyl hydrolase 43 family
S101444_04031	COG2986	histidine ammonia-lyase
S101444_04032	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
S101444_04033	COG1228	amidohydrolase
S101444_04034	COG0010	Belongs to the arginase family
S101444_04035	COG0833	amino acid
S101444_04036	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
S101444_04037	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101444_04038	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
S101444_04039	COG2390	Transcriptional regulator
S101444_04041	COG3192	ethanolamine utilization protein
S101444_04042	COG2079	MmgE PrpD family protein
S101444_04044	COG1126	abc transporter atp-binding protein
S101444_04045	COG0765	amino acid transport
S101444_04046	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101444_04049	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
S101444_04050	COG0561	phosphatase activity
S101444_04056	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101444_04057	COG5294	Protein conserved in bacteria
S101444_04058	COG0577	efflux transmembrane transporter activity
S101444_04059	COG1136	(ABC) transporter
S101444_04060	COG2205	protein histidine kinase activity
S101444_04061	COG0745	RESPONSE REGULATOR receiver
S101444_04062	COG0191	fructose-bisphosphate aldolase activity
S101444_04063	COG1082	Xylose isomerase domain protein TIM barrel
S101444_04064	COG1082	Xylose isomerase domain protein TIM barrel
S101444_04065	COG0673	inositol 2-dehydrogenase activity
S101444_04066	COG2814	Major facilitator Superfamily
S101444_04067	COG1082	Xylose isomerase domain protein TIM barrel
S101444_04068	COG3962	Belongs to the TPP enzyme family
S101444_04069	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101444_04071	COG1012	belongs to the aldehyde dehydrogenase family
S101444_04072	COG1349	DNA-binding transcription factor activity
S101444_04073	COG0667	Aldo Keto reductase
S101444_04076	COG2814	Major facilitator Superfamily
S101444_04077	COG0326	Molecular chaperone. Has ATPase activity
S101444_04079	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_04080	COG1309	transcriptional regulator
S101444_04081	COG1012	belongs to the aldehyde dehydrogenase family
S101444_04082	COG1714	RDD family
S101444_04084	COG1714	RDD family
S101444_04085	COG2311	Membrane
S101444_04086	COG1917	Cupin 2, conserved barrel domain protein
S101444_04087	COG1309	transcriptional regulator
S101444_04088	COG1028	Short-chain dehydrogenase reductase Sdr
S101444_04089	COG1846	Transcriptional regulator
S101444_04090	COG1380	Effector of murein hydrolase LrgA
S101444_04091	COG1346	cytolysis
S101444_04092	COG5039	Polysaccharide pyruvyl transferase
S101444_04093	COG1929	Belongs to the glycerate kinase type-1 family
S101444_04094	COG1802	Transcriptional regulator
S101444_04095	COG1070	Carbohydrate kinase
S101444_04096	COG2610	gluconate transmembrane transporter activity
S101444_04097	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S101444_04098	COG0450	alkyl hydroperoxide reductase
S101444_04099	COG3634	alkyl hydroperoxide reductase activity
S101444_04100	COG2723	6-phospho-beta-galactosidase activity
S101444_04101	COG1263	PTS System
S101444_04101	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101444_04101	COG2190	(PTS) system
S101444_04102	COG2188	Transcriptional regulator
S101444_04103	COG1074	ATP-dependent DNA helicase activity
S101444_04104	COG0501	Belongs to the peptidase M48B family
S101444_04108	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
S101444_04110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
S101444_04113	COG1063	alcohol dehydrogenase
S101444_04117	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
S101444_04118	COG0456	acetyltransferase
S101444_04119	COG0457	Tetratricopeptide repeat
S101444_04120	COG0457	Tetratricopeptide repeat
S101444_04122	COG0010	Belongs to the arginase family
S101444_04123	COG0833	amino acid
S101444_04124	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101444_04128	COG5658	integral membrane protein
S101444_04129	COG0640	Transcriptional regulator
S101444_04130	COG3829	transcription factor binding
S101444_04131	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101444_04132	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
S101444_04133	COG4853	Protein conserved in bacteria
S101444_04134	COG4863	YycH protein
S101444_04135	COG5002	protein histidine kinase activity
S101444_04136	COG0745	RESPONSE REGULATOR receiver
S101444_04142	COG0346	lactoylglutathione lyase activity
S101444_04143	COG0305	Participates in initiation and elongation during chromosome replication
S101444_04146	COG3093	addiction module antidote protein HigA
S101444_04147	COG2807	transmembrane transport
S101444_04148	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101444_04149	COG0359	binds to the 23S rRNA
S101444_04150	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
S101444_04151	COG4241	membrane
S101444_04153	COG5577	PFAM Coat F domain
S101444_04154	COG1733	regulation of RNA biosynthetic process
S101444_04155	COG1227	inorganic diphosphatase activity
S101444_04158	COG2271	Major facilitator Superfamily
S101444_04159	COG0789	Transcriptional regulator
S101444_04159	COG4978	Transcriptional regulator
S101444_04161	COG4319	ketosteroid isomerase
S101444_04162	COG1357	PFAM Pentapeptide repeats (8 copies)
S101444_04163	COG2814	Major facilitator Superfamily
S101444_04164	COG0583	DNA-binding transcription factor activity
S101444_04165	COG2153	protein acetylation
S101444_04167	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101444_04168	COG1846	Transcriptional regulator
S101444_04169	COG2153	protein acetylation
S101444_04170	COG2364	Membrane
S101444_04171	COG0456	acetyltransferase
S101444_04172	COG2315	Protein conserved in bacteria
S101444_04173	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101444_04174	COG1331	Highly conserved protein containing a thioredoxin domain
S101444_04175	COG1266	CAAX protease self-immunity
S101444_04176	COG0477	Major facilitator Superfamily
S101444_04176	COG2814	Major facilitator Superfamily
S101444_04177	COG0110	maltose O-acetyltransferase activity
S101444_04178	COG0346	lactoylglutathione lyase activity
S101444_04179	COG1609	Transcriptional regulator
S101444_04180	COG0708	Exodeoxyribonuclease III
S101444_04181	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
S101444_04182	COG0629	single-stranded DNA binding
S101444_04183	COG0360	Binds together with S18 to 16S ribosomal RNA
S101444_04184	COG0012	GTP binding
S101444_04185	COG0243	molybdopterin cofactor binding
S101444_04186	COG4481	Protein conserved in bacteria
S101444_04187	COG3949	Membrane
S101444_04189	COG1475	DNA binding
S101444_04190	COG1192	Involved in chromosome partitioning
S101444_04192	COG1475	DNA binding
S101444_04193	COG0357	Ribosomal RNA small subunit methyltransferase G
S101444_04194	COG0445	tRNA wobble uridine modification
S101444_04195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
S101444_04196	COG1847	R3H domain protein
S101444_04197	COG0706	membrane insertase activity
S101444_04198	COG0594	ribonuclease P activity