locus-tag	class	description
A8O17_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A8O17_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A8O17_00015	ENOG410848D	S4 domain protein YaaA
A8O17_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A8O17_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A8O17_00070	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A8O17_00080	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A8O17_00085	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A8O17_00090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A8O17_00100	ENOG4105ZMH	deoxynucleoside kinase
A8O17_00110	ENOG4105VRS	hydrolase family 18
A8O17_00115	ENOG4105GTG	Isochorismatase
A8O17_00120	ENOG4108Z6B	deaminase
A8O17_00130	ENOG4105C6E	dna polymerase iii
A8O17_00135	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A8O17_00140	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A8O17_00150	ENOG41067KS	pro-sigma K processing
A8O17_00190	ENOG4105CDW	Resistance protein
A8O17_00195	ENOG4105CXN	decarboxylase
A8O17_00200	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A8O17_00205	ENOG4105X0R	protein from nitrogen regulatory protein P-II
A8O17_00210	ENOG4105XVJ	Protein of unknown function (DUF327)
A8O17_00215	ENOG4105FA2	dna polymerase iii
A8O17_00220	ENOG4105MA4	psp1 domain protein
A8O17_00225	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
A8O17_00230	ENOG41060K3	Methyltransferase
A8O17_00235	ENOG4105VC4	domain protein
A8O17_00240	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A8O17_00245	ENOG4105KRN	Transcriptional regulator, abrb family
A8O17_00250	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A8O17_00255	ENOG4105F8V	Hydrolase, tatD family
A8O17_00260	ENOG41069ER	domain protein
A8O17_00270	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A8O17_00275	ENOG4105XFA	sporulation peptidase YabG
A8O17_00280	ENOG4105W42	Veg protein
A8O17_00285	ENOG4105XEW	small acid-soluble spore protein
A8O17_00290	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A8O17_00295	ENOG4105DFT	pur operon repressor
A8O17_00300	ENOG4105KME	endoribonuclease L-psp
A8O17_00305	ENOG4105K4W	Could be involved in septation (By similarity)
A8O17_00315	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A8O17_00320	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A8O17_00325	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A8O17_00330	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A8O17_00340	ENOG4108JA2	transcriptioN-repair coupling factor
A8O17_00345	ENOG4108M14	stage v sporulation protein t
A8O17_00355	ENOG4108IY2	MazG family
A8O17_00360	ENOG41082I2	s4 domain protein
A8O17_00365	ENOG4105VYY	sporulation protein yabp
A8O17_00380	ENOG41060GV	RNA binding s1 domain protein
A8O17_00410	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A8O17_00415	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A8O17_00420	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A8O17_00430	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A8O17_00435	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
A8O17_00440	ENOG4105C6T	cysteine synthase
A8O17_00445	ENOG4105CRQ	synthase (Component I)
A8O17_00450	ENOG4105DDQ	anthranilate synthase
A8O17_00455	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
A8O17_00460	ENOG4105EEI	dihydropteroate synthase
A8O17_00465	ENOG4105KRF	dihydroneopterin aldolase
A8O17_00470	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A8O17_00480	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A8O17_00485	ENOG4105CRK	lysyL-tRNA synthetase
A8O17_00575	ENOG4108Z0C	Uvrb UvrC protein
A8O17_00580	ENOG41066A3	ATP guanido phosphotransferase
A8O17_00590	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A8O17_00595	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
A8O17_00600	ENOG4105CTP	PilT protein domain protein
A8O17_00605	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A8O17_00610	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A8O17_00615	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A8O17_00625	ENOG4105D7W	serine acetyltransferase
A8O17_00630	ENOG4105C8N	cysteinyl-tRNA synthetase
A8O17_00635	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A8O17_00640	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A8O17_00645	ENOG4105M0M	Tetracycline resistance protein
A8O17_00665	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A8O17_00670	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A8O17_00680	ENOG4108VZM	50s ribosomal protein L10
A8O17_00685	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A8O17_00690	ENOG4107Y49	methyltransferase
A8O17_00695	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A8O17_00700	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A8O17_00705	ENOG4105XPM	ribosomal protein
A8O17_00710	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A8O17_00715	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A8O17_00720	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A8O17_00725	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A8O17_00730	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
A8O17_00735	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A8O17_00740	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A8O17_00745	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A8O17_00750	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A8O17_00755	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A8O17_00760	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A8O17_00765	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A8O17_00770	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A8O17_00775	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A8O17_00780	ENOG41082SA	50s ribosomal protein l29
A8O17_00785	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A8O17_00790	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A8O17_00800	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A8O17_00810	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A8O17_00815	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A8O17_00820	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A8O17_00825	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A8O17_00830	ENOG4105VPB	50S ribosomal protein L30
A8O17_00835	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A8O17_00840	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A8O17_00850	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A8O17_00860	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A8O17_00870	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A8O17_00875	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A8O17_00880	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A8O17_00885	ENOG4108ZT0	50S ribosomal protein l17
A8O17_00890	ENOG4108JJB	ABC transporter
A8O17_00895	ENOG4108JJB	ABC transporter
A8O17_00900	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A8O17_00905	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A8O17_00910	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A8O17_00915	ENOG4108UJD	30S ribosomal protein S9
A8O17_00920	ENOG4108I0C	methyltransferase
A8O17_00935	ENOG4105D1F	ATP-binding protein
A8O17_00950	ENOG4108NMV	polysaccharide deacetylase
A8O17_01035	ENOG4105CHH	sulfate transporter
A8O17_01045	ENOG4108SA1	esterase
A8O17_01065	ENOG410874W	AraC family transcriptional regulator
A8O17_01070	ENOG4105EHZ	conserved protein UCP016719
A8O17_01075	ENOG4105D17	glycoside hydrolase, family 3 domain protein
A8O17_01095	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A8O17_01105	ENOG4105EWC	Purine nucleoside phosphorylase
A8O17_01135	ENOG4105EMN	RNA polymerase sigma factor
A8O17_01145	ENOG4105C8B	TIGR00159 family
A8O17_01150	ENOG4107U5W	ybbr family
A8O17_01155	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A8O17_01160	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A8O17_01185	ENOG4105G0J	serine threonine protein kinase
A8O17_01195	ENOG4106K80	
A8O17_01205	ENOG4106DDH	Sporulation-specific SASP protein
A8O17_01215	ENOG4108HWY	Beta-lactamase
A8O17_01220	ENOG4107E6A	Cytochrome p-450
A8O17_01230	ENOG4107QTZ	amino acid
A8O17_01235	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
A8O17_01240	ENOG4105CXY	transporter
A8O17_01250	ENOG410645S	MarR family Transcriptional regulator
A8O17_01255	ENOG4105DCM	major facilitator superfamily
A8O17_01275	ENOG410631K	Membrane
A8O17_01280	ENOG4106AXJ	AraC family transcriptional regulator
A8O17_01285	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A8O17_01290	ENOG4108TCS	Glutamyl endopeptidase
A8O17_01300	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
A8O17_01305	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A8O17_01310	ENOG4107ZTW	SNARE associated Golgi
A8O17_01335	ENOG4105C72	UPF0176 protein
A8O17_01345	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
A8O17_01350	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A8O17_01355	ENOG4108X79	transcriptional regulator
A8O17_01365	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A8O17_01370	ENOG4108IQI	permease
A8O17_01375	ENOG4108J5H	Homocysteine s-methyltransferase
A8O17_01390	ENOG4105CSV	Glutaminase
A8O17_01405	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
A8O17_01410	ENOG4105C26	Dehydrogenase
A8O17_01415	ENOG4105DJB	Major Facilitator Superfamily
A8O17_01420	ENOG4105EQX	glucarate dehydratase
A8O17_01425	ENOG41073TP	transcriptional regulator
A8O17_01430	ENOG4105CTX	dehydratase
A8O17_01445	ENOG4106UX7	integral membrane protein
A8O17_01450	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A8O17_01485	ENOG4105MUA	Resistance protein
A8O17_01495	ENOG4105DGI	Alkaline phosphatase
A8O17_01500	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A8O17_01505	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A8O17_01510	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A8O17_01515	ENOG4107EPV	Aminotransferase class V
A8O17_01520	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A8O17_01525	ENOG4105J7D	transcriptional regulator
A8O17_01530	ENOG4107RB3	L-asparaginase
A8O17_01535	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
A8O17_01545	ENOG41060AI	SEC-C motif
A8O17_01555	ENOG4107Y7X	LytTR
A8O17_01560	ENOG4108IUW	ABC transporter
A8O17_01565	ENOG4108SDH	ABC, transporter
A8O17_01570	ENOG4107SET	aldo keto reductase
A8O17_01600	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A8O17_01610	ENOG4105DSE	periplasmic solute binding protein
A8O17_01615	ENOG4105DIK	(ABC) transporter
A8O17_01625	ENOG4105DEN	Luciferase family
A8O17_01630	ENOG4108N0M	stress protein
A8O17_01635	ENOG4106FN3	tellurium resistance protein
A8O17_01640	ENOG4106FN3	tellurium resistance protein
A8O17_01645	ENOG4107TS3	membrane protein, TerC
A8O17_01650	ENOG4108TTB	tellurium resistance protein
A8O17_01660	ENOG41079KZ	Major Facilitator Superfamily
A8O17_01665	ENOG4107XZQ	multidrug resistance protein
A8O17_01670	ENOG4108A65	Transcriptional regulator
A8O17_01675	ENOG4108IJ7	Glycine betaine
A8O17_01680	ENOG4107SQ8	Glycine betaine
A8O17_01715	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A8O17_01750	ENOG4105EIG	urea carboxylase-associated protein 1
A8O17_01755	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
A8O17_01760	ENOG4105I1F	Resistance protein
A8O17_01765	ENOG4107Z3Y	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A8O17_01770	ENOG41089UC	methyltransferase, type 11
A8O17_01775	ENOG4105C5Q	Transcriptional regulator
A8O17_01780	ENOG4105I82	acetyl xylan esterase
A8O17_01785	ENOG410756H	nucleotidyltransferase
A8O17_01795	ENOG4105C26	Dehydrogenase
A8O17_01800	ENOG4105CK7	Sodium proline symporter
A8O17_01805	ENOG4107YHD	transcriptional regulator
A8O17_01815	ENOG4108PJD	permease
A8O17_01820	ENOG4105U6C	Alpha beta hydrolase fold protein
A8O17_01830	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A8O17_01835	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
A8O17_01840	ENOG4108IFG	nitrite reductase, (NAD(P)H)
A8O17_01845	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A8O17_01865	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
A8O17_01875	ENOG4105CKI	cobalamin synthesis protein
A8O17_01880	ENOG4105E5Q	amino acid AbC transporter
A8O17_01885	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
A8O17_01895	ENOG4105HHM	rdd domain containing protein
A8O17_01905	ENOG4105CS2	ec 3.2.1.21
A8O17_01920	ENOG4105C8Q	Methyl-accepting chemotaxis
A8O17_01925	ENOG41080HJ	6-phospho 3-hexuloisomerase
A8O17_01930	ENOG4108VA3	3-hexulose-6-phosphate synthase
A8O17_01935	ENOG4105KVH	Transcriptional regulator
A8O17_01945	ENOG4105CEY	Amp-dependent synthetase and ligase
A8O17_01975	ENOG4105SX7	Transporter
A8O17_01985	ENOG4105W8Z	4'-phosphopantetheinyl transferase
A8O17_01995	ENOG4105CDA	abc transporter atp-binding protein
A8O17_02000	ENOG4105DRP	amino acid AbC transporter
A8O17_02010	ENOG4106P55	Transcriptional regulator
A8O17_02015	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A8O17_02020	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A8O17_02025	ENOG41069ZX	
A8O17_02030	ENOG41069ZX	
A8O17_02040	ENOG4105DUX	Transporter
A8O17_02055	ENOG4105E1K	spore germination protein
A8O17_02075	ENOG4107WD8	ABC transporter, permease
A8O17_02080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A8O17_02085	ENOG4105BZU	Histidine kinase
A8O17_02105	ENOG4105CFH	Aspartokinase
A8O17_02110	ENOG4105DHS	permease protein
A8O17_02115	ENOG4105CM4	permease protein
A8O17_02120	ENOG4108IPW	abc transporter atp-binding protein
A8O17_02135	ENOG4105R8C	Transcriptional regulator
A8O17_02140	ENOG4108DBC	nitroreductase
A8O17_02145	ENOG41067V3	Antibiotic biosynthesis monooxygenase
A8O17_02150	ENOG4105YVS	arsR family transcriptional regulator
A8O17_02160	ENOG4108JPW	Aminotransferase
A8O17_02165	ENOG4105C26	Dehydrogenase
A8O17_02175	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A8O17_02180	ENOG4105KTB	nuclear export factor GLE1
A8O17_02185	ENOG4108T5E	Copper resistance protein
A8O17_02190	ENOG4108ZYE	Transcriptional regulator
A8O17_02215	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A8O17_02220	ENOG4108ZX0	Signal peptidase I
A8O17_02250	ENOG4105E7W	lamb ycsf family protein
A8O17_02255	ENOG4105C5A	transporter
A8O17_02260	ENOG4105CFM	UPF0317 protein
A8O17_02265	ENOG4105P4J	Allophanate hydrolase, subunit 1
A8O17_02275	ENOG4107258	Transcriptional regulator
A8O17_02280	ENOG4105XJB	lipolytic protein G-D-S-L family
A8O17_02290	ENOG41061CK	Antibiotic biosynthesis monooxygenase
A8O17_02295	ENOG4107RVG	penicillin-binding protein
A8O17_02300	ENOG4107QM2	Aldo Keto reductase
A8O17_02305	ENOG4105ETD	TRANSCRIPTIONal
A8O17_02315	ENOG4105HMZ	Methyltransferase
A8O17_02320	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A8O17_02335	ENOG410606W	general stress protein
A8O17_02345	ENOG4105VCH	membrane
A8O17_02355	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A8O17_02370	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
A8O17_02375	ENOG4107R8N	Glycosyl transferase, family 2
A8O17_02385	ENOG4105C0X	amino acid
A8O17_02410	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
A8O17_02420	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
A8O17_02425	ENOG4105EU9	
A8O17_02430	ENOG4105QVS	general stress protein
A8O17_02435	ENOG41082W1	Cupin 2, conserved barrel domain protein
A8O17_02450	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A8O17_02455	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A8O17_02460	ENOG4108MRH	transcriptional regulatory protein
A8O17_02465	ENOG4107QJT	sodium dicarboxylate symporter
A8O17_02470	ENOG4106F5Q	Membrane
A8O17_02480	ENOG4105CJ1	ABC, transporter
A8O17_02495	ENOG4105FDT	acyl-CoA dehydrogenase
A8O17_02515	ENOG4105SZ6	Thioredoxin
A8O17_02520	ENOG4105CPF	Cell wall formation (By similarity)
A8O17_02525	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
A8O17_02530	ENOG4105C1J	atp-dependent rna helicase
A8O17_02535	ENOG410905X	membrane-flanked domain protein
A8O17_02540	ENOG4105CKV	Membrane
A8O17_02550	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A8O17_02555	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
A8O17_02560	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A8O17_02570	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
A8O17_02575	ENOG4107MMM	Anti-sigma-factor antagonist
A8O17_02580	ENOG4105FUA	antagonist
A8O17_02585	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
A8O17_02590	ENOG4107SGM	protein serine threonine phosphatase
A8O17_02595	ENOG4105WN5	stage II sporulation protein
A8O17_02600	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
A8O17_02610	ENOG41064BQ	Phosphatase
A8O17_02625	ENOG4105M5P	UPF0310 protein
A8O17_02630	ENOG4105RV9	Transcriptional regulator
A8O17_02685	ENOG4105DEN	Luciferase family
A8O17_02700	ENOG4108W2Y	isochorismatase
A8O17_02705	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
A8O17_02710	ENOG4108HH4	Major Facilitator Superfamily
A8O17_02730	ENOG4108V4B	ThiJ pfpI
A8O17_02735	ENOG4105VEQ	Cold shock protein
A8O17_02740	ENOG4108VJ1	Transcriptional regulator (CarD family
A8O17_02750	ENOG4108MCI	Transcriptional regulator, ARAC family
A8O17_02755	ENOG4108UZ3	Transporter
A8O17_02760	ENOG41086D8	Transcriptional regulator
A8O17_02765	ENOG4107U9B	transcriptional regulator
A8O17_02770	ENOG4105DXI	Major Facilitator superfamily
A8O17_02780	ENOG4105CZ9	Domain of unknown function (DU1801)
A8O17_02785	ENOG4105GIG	
A8O17_02790	ENOG4105T38	integral membrane protein
A8O17_02795	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A8O17_02800	ENOG4108ZMQ	domain protein
A8O17_02805	ENOG4105MJ9	esterase
A8O17_02810	ENOG4107Z6X	Transcriptional regulator
A8O17_02820	ENOG4105KVH	Transcriptional regulator
A8O17_02825	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A8O17_02830	ENOG4105EQ0	Major Facilitator superfamily
A8O17_02835	ENOG4108JGH	Tetr family transcriptional regulator
A8O17_02845	ENOG41082YX	Transcriptional regulator, arsr family
A8O17_02850	ENOG4107R5R	arsenical pump membrane protein
A8O17_02860	ENOG4105Z7P	Acetyltransferase (GNAT) family
A8O17_02865	ENOG4107Y9U	Membrane
A8O17_02875	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
A8O17_02880	ENOG4108ZHR	arsR family transcriptional regulator
A8O17_02885	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A8O17_02895	ENOG4105ENE	Histidine kinase
A8O17_02900	ENOG4108VB1	regulatoR
A8O17_02905	ENOG4105EYF	MMPL domain protein
A8O17_02910	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
A8O17_02915	ENOG4108UQV	Membrane
A8O17_02920	ENOG4108Z5V	transcriptional regulator, merr family
A8O17_02925	ENOG41076HS	cation diffusion facilitator family transporter
A8O17_02930	ENOG4108TVJ	Nitroreductase
A8O17_02935	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
A8O17_02940	ENOG4108VGI	doxx family
A8O17_02945	ENOG4105XXY	Thioredoxin
A8O17_02965	ENOG410900G	Protein of unknown function (DUF421)
A8O17_02970	ENOG4108QY0	Membrane
A8O17_02990	ENOG4105PF9	Transcriptional regulator
A8O17_03000	ENOG4105WQG	acetyltransferase
A8O17_03010	ENOG4105C85	amino acid
A8O17_03020	ENOG41062A4	Transcriptional regulator
A8O17_03025	ENOG4105EYF	MMPL domain protein
A8O17_03030	ENOG4108TVJ	Nitroreductase
A8O17_03035	ENOG4105FS7	Transcriptional regulator
A8O17_03040	ENOG4105C2C	drug resistance transporter, Bcr CflA
A8O17_03050	ENOG4105DRR	Transcriptional regulator, GntR family
A8O17_03055	ENOG4105VRS	hydrolase family 18
A8O17_03070	ENOG4105G6Z	alkaline phosphatase
A8O17_03075	ENOG4108ZMX	Domain of unknown function (DU1801)
A8O17_03085	ENOG4108YM7	Gcn5-related n-acetyltransferase
A8O17_03090	ENOG4107TVP	HD domain protein
A8O17_03095	ENOG41090UD	(LipO)protein
A8O17_03100	ENOG4105F27	Major Facilitator
A8O17_03105	ENOG4105VZJ	PTS System
A8O17_03110	ENOG4105VCP	PTS System
A8O17_03115	ENOG4105CK1	PTS System
A8O17_03120	ENOG4105CS2	ec 3.2.1.21
A8O17_03125	ENOG4108TZY	GntR Family Transcriptional Regulator
A8O17_03130	ENOG4105EVU	fructokinase
A8O17_03135	ENOG4105DG6	mannose-6-phosphate isomerase
A8O17_03140	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
A8O17_03185	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A8O17_03190	ENOG4105K8N	protein family UPF0079, ATPase
A8O17_03195	ENOG41072GX	Peptidase M22 Glycoprotease
A8O17_03200	ENOG410801F	ribosomal-protein-alanine acetyltransferase
A8O17_03205	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A8O17_03210	ENOG4105C5H	ABC transporter
A8O17_03215	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A8O17_03220	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
A8O17_03225	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A8O17_03230	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A8O17_03240	ENOG4108TYN	CAAX amino terminal protease family protein
A8O17_03245	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A8O17_03250	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A8O17_03265	ENOG4105PGZ	NB-ARC domain
A8O17_03270	ENOG4105CPQ	Dehydrogenase
A8O17_03275	ENOG4105CT4	transporter
A8O17_03285	ENOG41087YS	Phage shock protein A
A8O17_03290	ENOG4105DQX	Zinc finger domain
A8O17_03295	ENOG4108WV1	Pfam:DUF477
A8O17_03305	ENOG4108ZMR	Ion transport 2 domain-containing protein
A8O17_03310	ENOG4107QNK	)-transporter
A8O17_03340	ENOG4107YUH	hydrolase
A8O17_03350	ENOG4107STQ	Multicopper oxidase
A8O17_03355	ENOG4105C85	amino acid
A8O17_03370	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A8O17_03390	ENOG4105C7N	Xanthine uracil vitamin C permease
A8O17_03415	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A8O17_03420	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A8O17_03425	ENOG4105C83	adenylosuccinate lyase
A8O17_03430	ENOG4105C8V	SAICAR synthetase
A8O17_03435	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
A8O17_03440	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A8O17_03445	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A8O17_03455	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A8O17_03460	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A8O17_03465	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A8O17_03470	ENOG4105C12	Phosphoribosylglycinamide synthetase
A8O17_03480	ENOG4105DVH	amino acid
A8O17_03495	ENOG4108R5T	secreted protein
A8O17_03500	ENOG4105KGF	protein, YerC YecD
A8O17_03505	ENOG4105CBC	glutamate synthase
A8O17_03515	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
A8O17_03520	ENOG4105C4R	Atp-dependent dna helicase
A8O17_03525	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A8O17_03535	ENOG4105CRN	Aminoglycoside phosphotransferase
A8O17_03540	ENOG4105KT7	mgtC SapB transporter
A8O17_03545	ENOG4105CK7	Sodium proline symporter
A8O17_03550	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A8O17_03555	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A8O17_03560	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A8O17_03565	ENOG4108IG5	Transcriptional regulator
A8O17_03575	ENOG4105CBD	Diacylglycerol kinase
A8O17_03580	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A8O17_03595	ENOG4105D85	methylase
A8O17_03600	ENOG4105F6A	helicase
A8O17_03605	ENOG4105ECI	YeeC-like protein
A8O17_03645	ENOG4105CDY	transcriptional regulatory protein
A8O17_03655	ENOG4105M4P	Tetr family transcriptional regulator
A8O17_03660	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
A8O17_03665	ENOG4107S9F	NmrA family
A8O17_03680	ENOG4105WEF	catalase
A8O17_03685	ENOG4105M18	-acetyltransferase
A8O17_03700	ENOG4105C2F	Histidine kinase
A8O17_03705	ENOG4105EQD	regulatoR
A8O17_03710	ENOG410769Z	extracellular solute-binding protein family 1
A8O17_03715	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
A8O17_03720	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
A8O17_03725	ENOG4105F5H	Glycosyl Hydrolase Family 88
A8O17_03730	ENOG41075H3	AraC family transcriptional regulator
A8O17_03735	ENOG4107TDE	lipolytic protein G-D-S-L family
A8O17_03750	ENOG4105CX8	fg-gap repeat protein
A8O17_03755	ENOG4105CX8	fg-gap repeat protein
A8O17_03760	ENOG4107TDE	lipolytic protein G-D-S-L family
A8O17_03770	ENOG4105EKC	
A8O17_03775	ENOG4105E0S	extracellular solute-binding protein family 1
A8O17_03785	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A8O17_03790	ENOG4105F8D	glycoside hydrolase family 4
A8O17_03795	ENOG4105H67	Protein of unknown function (DUF421)
A8O17_03800	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
A8O17_03805	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
A8O17_03825	ENOG4106I4J	membrane
A8O17_03830	ENOG4108PCN	EamA-like transporter family
A8O17_03835	ENOG41082F9	transcriptional regulator
A8O17_03840	ENOG41061H0	Monooxygenase
A8O17_03845	ENOG4108R1P	
A8O17_03850	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A8O17_03855	ENOG4105E0M	Sulfatase
A8O17_03860	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
A8O17_03870	ENOG41090R9	glycosyltransferase
A8O17_03875	ENOG4107R51	Glycosyl transferase, family 2
A8O17_03880	ENOG41090R9	glycosyltransferase
A8O17_03885	ENOG4105EU0	Major facilitator Superfamily
A8O17_03895	ENOG4105CUB	amino acid
A8O17_03900	ENOG4105C26	Dehydrogenase
A8O17_03905	ENOG4105FKZ	Methyl-accepting chemotaxis
A8O17_03910	ENOG4105C5H	ABC transporter
A8O17_03920	ENOG4107SWG	transcriptional regulator MERR family
A8O17_03925	ENOG4105DXB	Major Facilitator superfamily
A8O17_03940	ENOG4105C5H	ABC transporter
A8O17_03945	ENOG4105FDU	atp-dependent rna helicase
A8O17_03955	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A8O17_03975	ENOG4105E6M	Sulphatase-modifying factor protein
A8O17_03980	ENOG4105E0A	ABC, transporter
A8O17_03985	ENOG4108U1V	ABC transporter, permease
A8O17_03990	ENOG4105DQ5	transport system permease protein
A8O17_03995	ENOG4108HUF	Transporter
A8O17_04010	ENOG4108J20	pectate lyase
A8O17_04015	ENOG4107QPK	)-transporter
A8O17_04025	ENOG4108MRH	transcriptional regulatory protein
A8O17_04055	ENOG410855V	Acylphosphatase
A8O17_04060	ENOG4108RPX	mosc domain containing protein
A8O17_04080	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
A8O17_04105	ENOG4105GEU	Spore germination protein
A8O17_04115	ENOG4108Q5U	germination protein, ger(x)c family
A8O17_04120	ENOG4105E1K	spore germination protein
A8O17_04125	ENOG4105C5Y	PTS System
A8O17_04130	ENOG4105CG3	alpha amylase, catalytic region
A8O17_04135	ENOG4107414	GntR family transcriptional regulator
A8O17_04140	ENOG4108RCM	Nitroreductase
A8O17_04145	ENOG4105CGH	5'-nucleotidase
A8O17_04150	ENOG4107RKG	DJ-1/PfpI family
A8O17_04165	ENOG4105KJF	protein tyrosine phosphatase
A8O17_04175	ENOG4107U9T	Pfam:Ribonuclease_BN
A8O17_04185	ENOG4108ISG	Major Facilitator
A8O17_04195	ENOG4105UPD	Calcium Proton
A8O17_04205	ENOG4105D8X	mechanosensitive ion channel
A8O17_04225	ENOG4106KE4	Dehydrogenase
A8O17_04230	ENOG4105D7N	magnesium and cobalt transport protein CorA
A8O17_04240	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A8O17_04265	ENOG4107RUY	(E1 component), alpha subunit
A8O17_04275	ENOG4107QKR	Dehydrogenase
A8O17_04285	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
A8O17_04290	ENOG41069DP	small acid-soluble spore protein
A8O17_04295	ENOG4105KK4	UPF0060 membrane protein
A8O17_04325	ENOG4105F8D	glycoside hydrolase family 4
A8O17_04330	ENOG4108Q3X	Transcriptional regulator
A8O17_04335	ENOG4105CI1	PTS System
A8O17_04340	ENOG4105BZ1	(ABC) transporter
A8O17_04345	ENOG4105BZ1	(ABC) transporter
A8O17_04355	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
A8O17_04360	ENOG4105ID8	Transcriptional regulator, ARAC family
A8O17_04365	ENOG4107QNK	)-transporter
A8O17_04370	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
A8O17_04375	ENOG4105CIB	oxidoreductase Domain protein
A8O17_04380	ENOG4105BZU	Histidine kinase
A8O17_04385	ENOG4105WH1	Two component transcriptional regulator luxr family
A8O17_04390	ENOG4105CJ1	ABC, transporter
A8O17_04395	ENOG41090VJ	ABC-2 type transporter
A8O17_04400	ENOG4108KYE	ABC-2 type transporter
A8O17_04405	ENOG4105U3E	Transcriptional regulator
A8O17_04410	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
A8O17_04415	ENOG4105H93	Acyltransferase family
A8O17_04420	ENOG4105YA8	Transcriptional regulator
A8O17_04425	ENOG4107Y80	Major Facilitator superfamily
A8O17_04430	ENOG4108YYS	metal-dependent hydrolase (By similarity)
A8O17_04435	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A8O17_04440	ENOG410834F	Transcriptional regulator
A8O17_04450	ENOG4108MES	Periplasmic binding protein
A8O17_04455	ENOG4105DQ5	transport system permease protein
A8O17_04460	ENOG4108IHU	transport system permease protein
A8O17_04465	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A8O17_04470	ENOG4107Y03	Nitroreductase
A8O17_04485	ENOG4105ECP	epimerase
A8O17_04505	ENOG4105F27	Major Facilitator
A8O17_04525	ENOG4106AKJ	
A8O17_04530	ENOG4105D74	hydrolase
A8O17_04535	ENOG4105CKK	Glycosyl transferase, family 2
A8O17_04540	ENOG4105EJV	Membrane
A8O17_04545	ENOG41067AE	Membrane-bound metal-dependent hydrolase
A8O17_04550	ENOG4105CEN	a g-specific adenine glycosylase
A8O17_04555	ENOG4106BXE	
A8O17_04560	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
A8O17_04575	ENOG4105EVI	UPF0374 protein
A8O17_04580	ENOG4105BZ1	(ABC) transporter
A8O17_04585	ENOG4107NBY	Membrane
A8O17_04595	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8O17_04600	ENOG4105G5W	regulator Fur family
A8O17_04715	ENOG4108N23	SpoOM-related protein
A8O17_04730	ENOG4105EC3	peptidase S51, dipeptidase E
A8O17_04735	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A8O17_04740	ENOG4105DNP	FAD linked oxidase domain protein
A8O17_04755	ENOG4105E2Y	ABC, transporter
A8O17_04760	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
A8O17_04765	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A8O17_04770	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A8O17_04780	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A8O17_04785	ENOG4107D63	
A8O17_04790	ENOG4105VZ8	Transcriptional regulator
A8O17_04805	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A8O17_04815	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A8O17_04835	ENOG4105CYN	Serine protein kinase
A8O17_04840	ENOG4106AKX	UPF0229 protein
A8O17_04850	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
A8O17_04855	ENOG4105CW7	secretion protein, HlyD family
A8O17_04860	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A8O17_04865	ENOG4105CS1	NAD(P)H quinone oxidoreductase
A8O17_04880	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
A8O17_04885	ENOG4105CZV	ABC transporter
A8O17_04890	ENOG4105CJ1	ABC, transporter
A8O17_04895	ENOG4108TU7	Inherit from COG: (ABC) transporter
A8O17_04900	ENOG4105VEQ	Cold shock protein
A8O17_04915	ENOG4105BZU	Histidine kinase
A8O17_04955	ENOG4108YBP	pseudouridine synthase
A8O17_04965	ENOG41080XP	Cbs domain
A8O17_04970	ENOG4107YBY	Hydrolase
A8O17_04975	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A8O17_04980	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A8O17_04985	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
A8O17_04995	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A8O17_05000	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A8O17_05010	ENOG4105BZU	Histidine kinase
A8O17_05015	ENOG4105WH1	Two component transcriptional regulator luxr family
A8O17_05050	ENOG4105ED1	spovr family
A8O17_05055	ENOG4105G6Z	alkaline phosphatase
A8O17_05070	ENOG4105BZN	citrate synthase
A8O17_05075	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A8O17_05080	ENOG4105CUB	amino acid
A8O17_05085	ENOG4105C8J	)-transporter
A8O17_05090	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A8O17_05105	ENOG4105J37	
A8O17_05110	ENOG4108AEY	RNA polymerase sigma factor
A8O17_05115	ENOG4108FN7	Aldo keto reductase
A8O17_05120	ENOG4105F6E	Acyl-transferase
A8O17_05125	ENOG4105C37	(CBS) domain
A8O17_05135	ENOG4105CHM	Aminotransferase
A8O17_05140	ENOG4105C37	(CBS) domain
A8O17_05150	ENOG4105WMR	Protein CrcB homolog
A8O17_05155	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A8O17_05165	ENOG4105D64	Mechanosensitive ion channel
A8O17_05170	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A8O17_05175	ENOG4107VMI	polysaccharide deacetylase
A8O17_05180	ENOG4105F0I	Aminotransferase
A8O17_05200	ENOG4105BZ1	(ABC) transporter
A8O17_05205	ENOG4105BZ1	(ABC) transporter
A8O17_05225	ENOG410839P	
A8O17_05235	ENOG4106MP8	UPF0754 membrane protein
A8O17_05240	ENOG4105WZB	UPF0342 protein
A8O17_05245	ENOG4105F1N	DNA alkylation repair
A8O17_05255	ENOG4105D4P	Coproporphyrinogen iii oxidase
A8O17_05260	ENOG4107S91	Sodium hydrogen exchanger
A8O17_05265	ENOG4105NCW	Trka-c domain protein
A8O17_05275	ENOG4105CGU	Enoyl-CoA hydratase
A8O17_05285	ENOG4108IUX	(ABC) transporter
A8O17_05290	ENOG4105RHA	ABC transporter, permease
A8O17_05295	ENOG4107VRP	DNA repair exonuclease
A8O17_05300	ENOG4106D4I	domain protein
A8O17_05305	ENOG4105EQI	Metal Dependent Phosphohydrolase
A8O17_05315	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
A8O17_05350	ENOG4105NBU	tryptophan transport protein
A8O17_05355	ENOG4105DXJ	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A8O17_05360	ENOG4105K59	histidine triad (HIT) protein
A8O17_05395	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
A8O17_05400	ENOG4105BZ4	penicillin-binding protein
A8O17_05405	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A8O17_05410	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A8O17_05415	ENOG4105C1Q	protoporphyrinogen oxidase
A8O17_05425	ENOG4105ECB	domain protein
A8O17_05435	ENOG41090T1	Membrane
A8O17_05445	ENOG4105DER	m42 family
A8O17_05460	ENOG4106AXD	
A8O17_05465	ENOG4108RQ5	Beta-lactamase domain-containing protein
A8O17_05470	ENOG4105DF9	Lipoate-protein, ligase
A8O17_05480	ENOG4105CEY	Amp-dependent synthetase and ligase
A8O17_05490	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
A8O17_05495	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A8O17_05500	ENOG4105KD7	acetyltransferase
A8O17_05510	ENOG4108HUF	Transporter
A8O17_05515	ENOG4107TB6	phosphoglycerate mutase
A8O17_05525	ENOG4107F3J	Amp-dependent synthetase and ligase
A8O17_05530	ENOG4107ZYJ	bioY protein
A8O17_05535	ENOG4106YBV	Methyl-accepting chemotaxis
A8O17_05555	ENOG4105XVF	Competence transcription factor
A8O17_05560	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A8O17_05565	ENOG4105X3H	Excalibur domain protein
A8O17_05570	ENOG4105E1V	na solute symporter
A8O17_05575	ENOG4106CAD	Protein of unknown function (DUF3311)
A8O17_05580	ENOG41060YP	
A8O17_05595	ENOG4107SCK	Monooxygenase
A8O17_05600	ENOG4108INS	Transcriptional regulator
A8O17_05615	ENOG4105TRI	Hydrolase
A8O17_05630	ENOG4108KK1	membrane protein AbrB duplication
A8O17_05635	ENOG4106K7D	Major facilitator family transporter
A8O17_05640	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
A8O17_05645	ENOG4105VWP	Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding
A8O17_05660	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A8O17_05670	ENOG4105EYH	Exonuclease
A8O17_05725	ENOG4105ERH	Fumarylacetoacetate hydrolase
A8O17_05735	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A8O17_05745	ENOG4105CAQ	asparagine synthetase
A8O17_05760	ENOG4105UQX	Mate efflux family protein
A8O17_05765	ENOG4106HBX	Transcriptional Regulator AraC Family
A8O17_05770	ENOG4105ETE	Transcriptional regulator (LacI family
A8O17_05775	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A8O17_05780	ENOG4105SF0	DinB family
A8O17_05785	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
A8O17_05790	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A8O17_05795	ENOG4105MYW	Pentapeptide repeat protein
A8O17_05800	ENOG4107S9D	Alpha beta hydrolase
A8O17_05805	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A8O17_05810	ENOG4107RIQ	Sulfate adenylate transferase
A8O17_05815	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A8O17_05820	ENOG4108N5B	2-phosphosulfolactate phosphatase
A8O17_05825	ENOG41061P3	phosphosulfolactate synthase
A8O17_05835	ENOG4105DIA	mandelate racemase muconate lactonizing
A8O17_05840	ENOG4107RCC	Major Facilitator Superfamily
A8O17_05845	ENOG4108SZE	gCN5-related N-acetyltransferase
A8O17_05850	ENOG4105MA6	gCN5-related N-acetyltransferase
A8O17_05860	ENOG4108VPT	UPF0234 protein
A8O17_05865	ENOG4105QNR	S1 RNA binding domain protein
A8O17_05885	ENOG4105K7K	Transcriptional regulator
A8O17_05895	ENOG410751J	
A8O17_05900	ENOG4105D4Y	metalloprotease
A8O17_05905	ENOG4105EPR	degv family
A8O17_05910	ENOG4107AYK	membrAne
A8O17_05920	ENOG41073B9	
A8O17_05930	ENOG4108KP7	hydrolase
A8O17_05935	ENOG4108MXZ	Esterase
A8O17_05940	ENOG4105VG1	fes assembly suf system protein
A8O17_05950	ENOG4105IQ5	FAD linked oxidase domain protein
A8O17_05960	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A8O17_05975	ENOG4105C8Y	Acetylornithine aminotransferase
A8O17_05980	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A8O17_05990	ENOG4105DBV	ornithine carbamoyltransferase
A8O17_06015	ENOG4107RMD	Basic membrane lipoprotein
A8O17_06030	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A8O17_06035	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A8O17_06045	ENOG4105C3U	ABC transporter
A8O17_06050	ENOG4108JQ7	(ABC) transporter
A8O17_06065	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8O17_06075	ENOG4105C31	Tryptophanyl-tRNA synthetase
A8O17_06080	ENOG4108J59	Extracellular solute-binding protein, family 5
A8O17_06085	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8O17_06090	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8O17_06100	ENOG4108JQ7	(ABC) transporter
A8O17_06115	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
A8O17_06120	ENOG4108ZCF	integral membrane protein
A8O17_06125	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
A8O17_06135	ENOG4105DPN	Oligoendopeptidase f
A8O17_06150	ENOG4105T58	Dithiol-disulfide isomerase
A8O17_06155	ENOG4108Z18	K06886 hemoglobin
A8O17_06160	ENOG4105E4C	Lytic transglycosylase catalytic
A8O17_06165	ENOG4105MIX	Adenylate cyclase
A8O17_06180	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A8O17_06185	ENOG4105EMS	pseudouridine synthase
A8O17_06200	ENOG4105ETU	transcriptional activator (TenA
A8O17_06205	ENOG4108VEU	Thiamine monophosphate synthase
A8O17_06220	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A8O17_06225	ENOG4105D06	uba thif-type nad fad binding protein
A8O17_06230	ENOG4105DWF	phosphomethylpyrimidine kinase
A8O17_06235	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A8O17_06240	ENOG4107A88	
A8O17_06295	ENOG4105ENA	helicase
A8O17_06310	ENOG4108ZMI	UPF0477 protein
A8O17_06320	ENOG4105C28	cystathionine
A8O17_06325	ENOG4105C28	cystathionine
A8O17_06330	ENOG4105D9U	N-acetyltransferase
A8O17_06335	ENOG4105JHY	Membrane
A8O17_06350	ENOG41068SY	
A8O17_06370	ENOG4107KNS	
A8O17_06395	ENOG4108PSK	reductase
A8O17_06410	ENOG4105DM4	PTS System
A8O17_06415	ENOG4105DG6	mannose-6-phosphate isomerase
A8O17_06420	ENOG4105G7B	Protein of unknown function (DUF2992)
A8O17_06425	ENOG4105VMI	-acetyltransferase
A8O17_06435	ENOG4108Z66	YbaK ebsC protein
A8O17_06450	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A8O17_06460	ENOG4108ZJ4	polysaccharide deacetylase
A8O17_06465	ENOG4107CUJ	Protein of unknown function (DUF2690)
A8O17_06495	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A8O17_06520	ENOG4106A3M	Cytochrome p-450
A8O17_06525	ENOG41087PP	glycosyltransferase MGT family
A8O17_06535	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
A8O17_06540	ENOG4105C4B	ABC transporter, permease
A8O17_06545	ENOG4108IXI	(ABC) transporter
A8O17_06555	ENOG4105Q95	Cupin 2, conserved barrel domain protein
A8O17_06570	ENOG4105D2H	Uronic isomerase
A8O17_06575	ENOG4105CT4	transporter
A8O17_06580	ENOG4105DG4	malate L-lactate dehydrogenase
A8O17_06585	ENOG4105CPQ	Dehydrogenase
A8O17_06590	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
A8O17_06595	ENOG4105DMW	Dehydrogenase reductase
A8O17_06600	ENOG4108I5G	Major Facilitator superfamily
A8O17_06605	ENOG4107KJX	Transcriptional regulator
A8O17_06610	ENOG4107QZW	Altronate oxidoreductase
A8O17_06615	ENOG4105CTX	dehydratase
A8O17_06620	ENOG4107TSN	permease
A8O17_06640	ENOG4105CJ3	phosphate transporter
A8O17_06645	ENOG4107GRR	phosphate transport regulator
A8O17_06650	ENOG4107R7I	amino acid
A8O17_06660	ENOG4105EDW	glycosyl transferase, family 39
A8O17_06665	ENOG4105CKK	Glycosyl transferase, family 2
A8O17_06675	ENOG4105C0H	protease
A8O17_06685	ENOG4108ME1	Peptidase M55 D-aminopeptidase
A8O17_06690	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A8O17_06695	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A8O17_06700	ENOG4105C3U	ABC transporter
A8O17_06710	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
A8O17_06715	ENOG4105DTQ	mandelate racemase muconate lactonizing
A8O17_06720	ENOG4107SN7	NLP P60 protein
A8O17_06725	ENOG4108JQ7	(ABC) transporter
A8O17_06730	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A8O17_06735	ENOG4107TUM	Amidinotransferase
A8O17_06740	ENOG4108S4H	thioesterase Superfamily protein
A8O17_06745	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A8O17_06765	ENOG4108428	Inherit from COG: -acetyltransferase
A8O17_06775	ENOG41080TC	multidrug resistance protein
A8O17_06780	ENOG4105CIY	formyltetrahydrofolate deformylase
A8O17_06785	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A8O17_06800	ENOG4105K56	Transcriptional regulator
A8O17_06805	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A8O17_06815	ENOG4107Y2X	deaminase
A8O17_06820	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A8O17_06825	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A8O17_06835	ENOG4108W7F	transporter, permease
A8O17_06840	ENOG4108JJB	ABC transporter
A8O17_06845	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
A8O17_06850	ENOG4108X43	YKOF domain protein
A8O17_06855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A8O17_06860	ENOG41062D9	Histidine kinase
A8O17_06870	ENOG4106849	propeptide, pepSY amd peptidase M4
A8O17_06890	ENOG4105CJW	magnesium transporter
A8O17_06895	ENOG4105V75	Transcriptional regulator
A8O17_06940	ENOG4105DQE	DNA ligase
A8O17_06945	ENOG4105FDF	Could be involved in DNA repair (By similarity)
A8O17_06950	ENOG4105BZU	Histidine kinase
A8O17_06955	ENOG4107T5V	SNARE associated Golgi
A8O17_06960	ENOG4107TS3	membrane protein, TerC
A8O17_06965	ENOG4108WZW	RNA polymerase sigma
A8O17_06975	ENOG410681C	small acid-soluble spore protein
A8O17_06985	ENOG4105D0M	Protease HtpX homolog
A8O17_07005	ENOG4108TGC	Acyltransferase
A8O17_07010	ENOG4105BZU	Histidine kinase
A8O17_07015	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A8O17_07025	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A8O17_07030	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
A8O17_07035	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A8O17_07045	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
A8O17_07050	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
A8O17_07055	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
A8O17_07060	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
A8O17_07080	ENOG4105BZU	Histidine kinase
A8O17_07085	ENOG41090MY	MarR family Transcriptional regulator
A8O17_07090	ENOG4105ER2	Ompa motb domain protein
A8O17_07095	ENOG4105E14	MotA TolQ exbB proton channel
A8O17_07105	ENOG4108K88	Membrane
A8O17_07110	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A8O17_07115	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
A8O17_07120	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A8O17_07125	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A8O17_07135	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
A8O17_07140	ENOG4105FEA	Spore maturation protein
A8O17_07180	ENOG4105F0V	Cell wall hydrolase
A8O17_07195	ENOG4105C59	p-type ATPase
A8O17_07205	ENOG4105DC7	peptidase M24
A8O17_07220	ENOG4105CID	antiterminator
A8O17_07230	ENOG4105KRI	phosphocarrier protein (HPr
A8O17_07235	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A8O17_07245	ENOG4105F6S	Spore photoproduct lyase
A8O17_07255	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
A8O17_07260	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A8O17_07265	ENOG4105K4I	Scp-like extracellular
A8O17_07275	ENOG4105BZU	Histidine kinase
A8O17_07280	ENOG4105CHM	Aminotransferase
A8O17_07290	ENOG4107R88	Chemotaxis protein (CheV)
A8O17_07295	ENOG4105UIN	
A8O17_07305	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
A8O17_07315	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
A8O17_07320	ENOG4105ESF	Peptidoglycan binding domain protein
A8O17_07325	ENOG4105ESF	Peptidoglycan binding domain protein
A8O17_07335	ENOG4105EPM	Diguanylate phosphodiesterase
A8O17_07345	ENOG4107IN1	Protein of unknown function (DUF1797)
A8O17_07350	ENOG4108XRC	Protein of unknown function (DUF458) 
A8O17_07380	ENOG4105NQC	Flavodoxin
A8O17_07390	ENOG4105CH2	amidohydrolase
A8O17_07400	ENOG4105D8X	mechanosensitive ion channel
A8O17_07405	ENOG4105D3R	alkyl hydroperoxide reductase
A8O17_07410	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8O17_07425	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A8O17_07430	ENOG4105D06	uba thif-type nad fad binding protein
A8O17_07435	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A8O17_07440	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
A8O17_07445	ENOG4108ZAF	Molybdopterin
A8O17_07450	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
A8O17_07455	ENOG4105BZ1	(ABC) transporter
A8O17_07460	ENOG4105BZ1	(ABC) transporter
A8O17_07470	ENOG4107X8C	Efflux transporter RND family MFP subunit
A8O17_07475	ENOG4105C19	ABC transporter
A8O17_07480	ENOG4107RBB	ABC transporter, permease
A8O17_07485	ENOG4105E98	transcriptional regulator DeoR family
A8O17_07490	ENOG4105DE4	1-phosphofructokinase
A8O17_07495	ENOG4105DM4	PTS System
A8O17_07500	ENOG4105C3F	Signal peptidase i
A8O17_07510	ENOG4105C5H	ABC transporter
A8O17_07515	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A8O17_07540	ENOG4105BZU	Histidine kinase
A8O17_07550	ENOG4107ZYR	domain protein
A8O17_07560	ENOG4105CN5	Metallo-Beta-Lactamase
A8O17_07570	ENOG4108X4Q	Hydrolase
A8O17_07575	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A8O17_07595	ENOG4105CPP	Dehydrogenase, E1 component
A8O17_07600	ENOG4105C7S	Dehydrogenase
A8O17_07605	ENOG4107QN2	dihydrolipoyl dehydrogenase
A8O17_07615	ENOG4105CXN	decarboxylase
A8O17_07620	ENOG4105WBI	UPF0223 protein
A8O17_07635	ENOG4105ECY	inositol monophosphatase
A8O17_07645	ENOG4105JQZ	Methyltransferase
A8O17_07685	ENOG4105CI3	gtp-binding protein typa
A8O17_07690	ENOG4105QA2	
A8O17_07705	ENOG4108IAB	Phoh family
A8O17_07715	ENOG4105CSV	Glutaminase
A8O17_07720	ENOG4105ZPI	UPF0358 protein
A8O17_07725	ENOG4105CNI	cell division protein FtsW
A8O17_07730	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A8O17_07740	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A8O17_07750	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A8O17_07755	ENOG4105CCU	oxidase (Subunit III)
A8O17_07760	ENOG41064X9	cytochrome C oxidase subunit IV
A8O17_07775	ENOG41080XQ	Signal transduction protein with cbs domains
A8O17_07780	ENOG4106UY4	Inherit from COG: Scp-like extracellular
A8O17_07800	ENOG4105WUC	UPF0298 protein
A8O17_07805	ENOG4106H78	methyltransferase
A8O17_07810	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A8O17_07815	ENOG4105H20	Sporulation integral membrane protein YlbJ
A8O17_07820	ENOG4105D78	K07001 NTE family protein
A8O17_07825	ENOG41063PX	domain protein
A8O17_07830	ENOG4105CDE	UPF0348 protein
A8O17_07840	ENOG4105KNH	Nucleic acid-binding protein
A8O17_07845	ENOG41067VY	50S ribosomal protein L32
A8O17_07870	ENOG4108V6E	Cell division protein mraZ
A8O17_07875	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A8O17_07885	ENOG4105CJN	penicillin-binding protein
A8O17_07895	ENOG4105CJN	penicillin-binding protein
A8O17_07905	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A8O17_07915	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A8O17_07920	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A8O17_07925	ENOG4105CNI	cell division protein FtsW
A8O17_07930	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A8O17_07935	ENOG4105D4A	Cell wall formation (By similarity)
A8O17_07940	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
A8O17_07945	ENOG4108R2U	division initiation protein
A8O17_07955	ENOG4105K67	small basic protein
A8O17_07960	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A8O17_07965	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A8O17_07975	ENOG4105FFI	sigma-e processing peptidase spoiiga
A8O17_07980	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8O17_07990	ENOG4105DKW	ABC transporter
A8O17_08000	ENOG4105WR5	sporulation protein, YlmC YmxH family
A8O17_08005	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A8O17_08010	ENOG4105DFA	alanine racemase domain protein
A8O17_08015	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
A8O17_08020	ENOG41067XK	integral membrane protein
A8O17_08025	ENOG4105DBK	s4 domain protein
A8O17_08035	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A8O17_08045	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A8O17_08050	ENOG4105C34	Pseudouridine synthase
A8O17_08055	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A8O17_08065	ENOG4105CXT	aspartate transcarbamylase
A8O17_08075	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A8O17_08080	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A8O17_08085	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A8O17_08090	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A8O17_08095	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A8O17_08100	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A8O17_08105	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A8O17_08115	ENOG4107S4M	Sulfate adenylate transferase
A8O17_08120	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A8O17_08125	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A8O17_08130	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
A8O17_08135	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
A8O17_08140	ENOG4105F23	Fibronectin-binding protein
A8O17_08150	ENOG4105DSJ	YicC domain protein
A8O17_08155	ENOG4105KC4	UPF0296 protein
A8O17_08160	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A8O17_08170	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A8O17_08175	ENOG4105C25	Primosomal protein n'
A8O17_08180	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A8O17_08185	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A8O17_08190	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A8O17_08195	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A8O17_08200	ENOG4108ZF3	Phosphatase
A8O17_08205	ENOG4105D9P	serine threonine protein kinase
A8O17_08210	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A8O17_08215	ENOG4105DJV	ribulose-phosphate 3-epimerase
A8O17_08220	ENOG4105FJ0	thiamine
A8O17_08230	ENOG4105VB9	50S ribosomal protein l28
A8O17_08235	ENOG4108ZAA	Alkaline-shock protein
A8O17_08240	ENOG4105DP4	dak2 domain fusion protein ylov
A8O17_08250	ENOG4105EJQ	L-serine dehydratase
A8O17_08255	ENOG4105CB5	ATP-dependent DNA helicase recG
A8O17_08260	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
A8O17_08270	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A8O17_08275	ENOG4105CHR	reductase
A8O17_08280	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A8O17_08285	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A8O17_08290	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A8O17_08295	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A8O17_08305	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
A8O17_08315	ENOG4105K5M	30s ribosomal protein S16
A8O17_08320	ENOG4108BW8	UPF0109 protein
A8O17_08330	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A8O17_08335	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A8O17_08340	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A8O17_08345	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A8O17_08350	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A8O17_08360	ENOG4105VM1	flagellar
A8O17_08365	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A8O17_08370	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A8O17_08375	ENOG4105C79	DNA protecting protein DprA
A8O17_08380	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A8O17_08385	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
A8O17_08390	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A8O17_08395	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A8O17_08400	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A8O17_08410	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
A8O17_08415	ENOG4108ZC9	flagellar basal-body rod protein flgc
A8O17_08420	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
A8O17_08425	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A8O17_08430	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A8O17_08445	ENOG4106YF4	Flagellar biosynthesis chaperone
A8O17_08455	ENOG410696Y	Flagellar hook-length control protein
A8O17_08460	ENOG410822I	Flagellar hook capping protein
A8O17_08465	ENOG4108JQA	flagellar
A8O17_08470	ENOG41068WV	flagellar FlbD family protein
A8O17_08480	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A8O17_08485	ENOG4105DD5	Flagellar motor switch protein
A8O17_08490	ENOG4107YTP	response regulator receiver protein
A8O17_08500	ENOG4105CN7	Flagellar biosynthetic protein FliP
A8O17_08505	ENOG4105VS8	Flagellar biosynthetic protein fliq
A8O17_08510	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A8O17_08515	ENOG4105D00	flagellar biosynthetic protein flhB
A8O17_08520	ENOG4105D7B	Flagellar biosynthesis protein flha
A8O17_08525	ENOG4105FZW	flagellar biosynthesis regulator FlhF
A8O17_08535	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A8O17_08540	ENOG4105CBS	Chea signal transduction histidine kinase
A8O17_08545	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
A8O17_08560	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8O17_08570	ENOG4105CE9	30S ribosomal protein S2
A8O17_08575	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A8O17_08585	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A8O17_08590	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A8O17_08595	ENOG4105KNE	Phosphatidate cytidylyltransferase
A8O17_08605	ENOG4105DZP	Membrane-associated zinc metalloprotease
A8O17_08610	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A8O17_08615	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A8O17_08620	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A8O17_08625	ENOG4105CHV	Transcription elongation factor NusA
A8O17_08630	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
A8O17_08635	ENOG4105VHM	ribosomal protein
A8O17_08640	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A8O17_08645	ENOG4105W7A	Protein of unknown function (DUF503)
A8O17_08650	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A8O17_08655	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A8O17_08660	ENOG4105DTN	riboflavin biosynthesis protein ribF
A8O17_08665	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A8O17_08670	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A8O17_08680	ENOG4105C1V	Peptidase, M16
A8O17_08695	ENOG4105E35	Dipicolinate synthase subunit A
A8O17_08700	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
A8O17_08705	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A8O17_08715	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A8O17_08725	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
A8O17_08735	ENOG4105CNU	cell division protein FtsK
A8O17_08740	ENOG4105FDP	GntR family transcriptional regulator
A8O17_08760	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
A8O17_08765	ENOG4105XZV	Protein of unknown function (DUF3243)
A8O17_08780	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A8O17_08785	ENOG4105CEV	competence damage-inducible protein
A8O17_08795	ENOG4108A04	Beta-lactamase
A8O17_08800	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
A8O17_08805	ENOG4105D48	metallophosphoesterase
A8O17_08810	ENOG4105MCT	stage V sporulation protein S
A8O17_08820	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A8O17_08825	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A8O17_08840	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A8O17_08845	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A8O17_08860	ENOG4105IIP	Membrane
A8O17_08875	ENOG4106A3M	Cytochrome p-450
A8O17_08890	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A8O17_08900	ENOG4105K7W	phage-related replication protein
A8O17_08905	ENOG4108X3M	OsmC Ohr family protein
A8O17_08910	ENOG410814C	multidrug resistance protein
A8O17_08930	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A8O17_08935	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A8O17_08950	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
A8O17_08955	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A8O17_08960	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A8O17_08965	ENOG4105U6W	MutT NUDIX family protein
A8O17_08970	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A8O17_08975	ENOG4106F1P	AAA ATPase, central domain protein
A8O17_08985	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A8O17_08990	ENOG4105CXI	aluminum resistance protein
A8O17_08995	ENOG4105KV4	Transcriptional regulator
A8O17_09000	ENOG4105C5F	glutamine synthetase
A8O17_09005	ENOG41079P0	
A8O17_09025	ENOG4107AUC	
A8O17_09055	ENOG410907G	
A8O17_09060	ENOG4105CT4	transporter
A8O17_09065	ENOG4105DSG	hydrolase family 43
A8O17_09070	ENOG4105E2R	ROK family
A8O17_09075	ENOG4105C93	Xylose Isomerase
A8O17_09080	ENOG4105CMG	Carbohydrate kinase
A8O17_09085	ENOG4107Y9E	nuclease
A8O17_09090	ENOG4105C54	Major Facilitator superfamily
A8O17_09095	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A8O17_09105	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A8O17_09115	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A8O17_09175	ENOG4108Q8B	Spore germination protein
A8O17_09180	ENOG4108NHD	germination protein
A8O17_09195	ENOG4105FVX	
A8O17_09205	ENOG4105K7W	phage-related replication protein
A8O17_09215	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
A8O17_09225	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A8O17_09235	ENOG4108SVB	resolvase
A8O17_09240	ENOG4105VPS	UPF0291 protein
A8O17_09245	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A8O17_09265	ENOG4107QIV	Cytochrome c biogenesis protein
A8O17_09290	ENOG4107DZX	Small, acid-soluble spore protein P
A8O17_09300	ENOG4108I0Z	Aconitate hydratase
A8O17_09305	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A8O17_09320	ENOG41067CD	Small, acid-soluble spore protein Tlp
A8O17_09330	ENOG4105MI2	
A8O17_09335	ENOG4105W8X	HesB YadR YfhF-family protein
A8O17_09340	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A8O17_09345	ENOG4105K4P	CoA-binding domain protein
A8O17_09350	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A8O17_09375	ENOG4107QWR	cellulase (EC 3.2.1.4)
A8O17_09385	ENOG4108MYR	Secreted protein
A8O17_09390	ENOG4107SYN	Glycosyl hydrolases family 43
A8O17_09405	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A8O17_09410	ENOG4107T5V	SNARE associated Golgi
A8O17_09420	ENOG4107QX3	carboxylase
A8O17_09425	ENOG4105E39	Enoyl-CoA hydratase
A8O17_09430	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A8O17_09435	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
A8O17_09440	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A8O17_09445	ENOG4105CEY	Amp-dependent synthetase and ligase
A8O17_09450	ENOG4105C1G	acyl-Coa dehydrogenase
A8O17_09465	ENOG4105F32	YngK protein
A8O17_09470	ENOG4106U2H	Protein of unknown function (DUF1360)
A8O17_09480	ENOG4105CEY	Amp-dependent synthetase and ligase
A8O17_09485	ENOG4105C0W	non-ribosomal peptide synthetase
A8O17_09495	ENOG4105C0W	non-ribosomal peptide synthetase
A8O17_09500	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
A8O17_09505	ENOG4108N2V	aldose 1-epimerase
A8O17_09510	ENOG4107QJQ	Mate efflux family protein
A8O17_09535	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A8O17_09540	ENOG4105SKE	transcriptional Regulator LysR family
A8O17_09545	ENOG4105CB2	alcohol dehydrogenase
A8O17_09550	ENOG4105BZ8	glutamate synthase
A8O17_09555	ENOG4105CBC	glutamate synthase
A8O17_09560	ENOG4105C5Q	Transcriptional regulator
A8O17_09565	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A8O17_09570	ENOG4105II7	pyrroline-5-carboxylate reductase
A8O17_09590	ENOG4108UB7	
A8O17_09595	ENOG41068WN	
A8O17_09600	ENOG4105IE8	Alpha-ketoglutarate permease
A8O17_09605	ENOG4107U6E	carbohydrate kinase FGGY
A8O17_09610	ENOG4108M3J	Dehydrogenase
A8O17_09615	ENOG4108J2R	molybdopterin oxidoreductase
A8O17_09640	ENOG4105EC8	Methyl-accepting chemotaxis
A8O17_09650	ENOG4108YQE	rare lipoprotein a
A8O17_09655	ENOG4105XPP	Protein of unknown function (DUF1275)
A8O17_09660	ENOG4108NR7	pectate lyase
A8O17_09665	ENOG4108RAV	Conserved protein
A8O17_09675	ENOG4105F0F	Oxalate decarboxylase
A8O17_09685	ENOG4105EPI	acetyltransferase, (GNAT) family
A8O17_09705	ENOG41073R8	VanW family
A8O17_09715	ENOG4105VMP	Transcriptional regulator
A8O17_09720	ENOG4105NX3	Membrane
A8O17_09730	ENOG4108Q5Y	Membrane
A8O17_09740	ENOG4108V4B	ThiJ pfpI
A8O17_09745	ENOG4108J4B	Beta-lactamase
A8O17_09765	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A8O17_09770	ENOG4107T94	Endo-14-beta-xylanase
A8O17_09780	ENOG4105YB8	TM2 domain containing protein
A8O17_09785	ENOG4108IMY	Transcriptional regulator
A8O17_09800	ENOG4108RAV	Conserved protein
A8O17_09805	ENOG4108J9Q	DNA ligase
A8O17_09810	ENOG41079CX	
A8O17_09835	ENOG410780I	phosphoprotein phosphatase activity
A8O17_09860	ENOG4105DB4	
A8O17_09875	ENOG4106ANW	SMI1_KNR4
A8O17_09880	ENOG4106BHF	
A8O17_09900	ENOG4108Z7R	Chaperone CsaA
A8O17_09905	ENOG4105FTV	AraC Family Transcriptional Regulator
A8O17_09910	ENOG4108HJF	gCN5-related N-acetyltransferase
A8O17_09920	ENOG4108W8B	Beta-lactamase domain protein
A8O17_09930	ENOG4105D29	Helix-turn-helix type 11 domain protein
A8O17_09940	ENOG4105KTU	Transcriptional regulator, arsr family
A8O17_09950	ENOG4108SJC	Membrane
A8O17_09970	ENOG4105ECK	Fatty Acid Desaturase
A8O17_09975	ENOG4108ZGX	Histidine kinase
A8O17_09980	ENOG4108S01	response regulator
A8O17_09985	ENOG41069ER	domain protein
A8O17_09990	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A8O17_10005	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A8O17_10010	ENOG4105SCY	DNAK suppressor
A8O17_10050	ENOG4105C26	Dehydrogenase
A8O17_10055	ENOG4105EWU	Squalene--hopene cyclase
A8O17_10060	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A8O17_10065	ENOG4105C8J	)-transporter
A8O17_10070	ENOG4105C09	Bile acid
A8O17_10075	ENOG4105C7S	Dehydrogenase
A8O17_10085	ENOG4107T89	von Willebrand factor, type A
A8O17_10090	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
A8O17_10100	ENOG4105K4H	Nlp p60 protein
A8O17_10105	ENOG41087PP	glycosyltransferase MGT family
A8O17_10115	ENOG4107QMU	Mate efflux family protein
A8O17_10120	ENOG4106SCS	STAS domain
A8O17_10140	ENOG4105FR1	rard protein
A8O17_10155	ENOG4105C6Z	Gluconate
A8O17_10160	ENOG41090U3	tautomerase
A8O17_10175	ENOG4105FBA	Phospholipase Carboxylesterase
A8O17_10190	ENOG4105E1V	na solute symporter
A8O17_10210	ENOG4108VXD	carboxy-peptidase
A8O17_10215	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A8O17_10225	ENOG4106Z5R	
A8O17_10230	ENOG410841Q	phosphoesterase PA-phosphatase related protein
A8O17_10265	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A8O17_10270	ENOG4108TSC	N-acetyltransferase
A8O17_10275	ENOG4107S4Y	M20 DapE family protein YgeY
A8O17_10290	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A8O17_10330	ENOG4107T32	3-phytase (EC 3.1.3.8)
A8O17_10335	ENOG4105C5E	polysaccharide biosynthesis protein
A8O17_10340	ENOG4105E0X	reductase
A8O17_10345	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A8O17_10365	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
A8O17_10370	ENOG41090WU	lipolytic protein G-D-S-L family
A8O17_10375	ENOG4108KF3	Electron transport protein SCO1 SenC
A8O17_10390	ENOG4105C7B	Threonine dehydratase
A8O17_10400	ENOG4108UT2	hemolysin iii
A8O17_10410	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
A8O17_10415	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A8O17_10430	ENOG4107YX5	Pfam:DUF548
A8O17_10435	ENOG4108Y6J	UPF0403 protein
A8O17_10440	ENOG4105C01	Dihydroxy-acid dehydratase
A8O17_10455	ENOG4108V06	Glutathione peroxidase
A8O17_10460	ENOG4105CVG	Homoserine O-transsuccinylase
A8O17_10500	ENOG41081VK	Ribonuclease
A8O17_10530	ENOG410890F	Dynamin family
A8O17_10540	ENOG41065KQ	synthase
A8O17_10545	ENOG4105C2W	permease
A8O17_10550	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
A8O17_10555	ENOG4105CTD	carboxy-peptidase
A8O17_10560	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
A8O17_10565	ENOG4108UHU	Aldolase
A8O17_10570	ENOG4105D7K	pfkb domain protein
A8O17_10575	ENOG4108M60	Transcriptional regulator
A8O17_10585	ENOG4105CHR	reductase
A8O17_10590	ENOG4105DVT	helicase
A8O17_10600	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A8O17_10615	ENOG4108UKS	UPF0398 protein
A8O17_10625	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
A8O17_10630	ENOG4108I5C	dEAD DEAH box helicase
A8O17_10680	ENOG4105BZ4	penicillin-binding protein
A8O17_10690	ENOG4105CSM	endonuclease III
A8O17_10700	ENOG4105C5S	asparaginyl-tRNA synthetase
A8O17_10705	ENOG4105CHM	Aminotransferase
A8O17_10715	ENOG4105YAC	
A8O17_10720	ENOG4105DVT	helicase
A8O17_10725	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
A8O17_10730	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A8O17_10735	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A8O17_10740	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A8O17_10745	ENOG4105DJ0	Poly(A) Polymerase
A8O17_10750	ENOG4105CPK	Glycosyl transferase (Group 1
A8O17_10755	ENOG4105FJR	Lmbe family
A8O17_10760	ENOG4108Z5K	methylglyoxal synthase
A8O17_10765	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A8O17_10770	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
A8O17_10775	ENOG4108JYZ	YitT family
A8O17_10795	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A8O17_10815	ENOG41068YB	TPR repeat-containing protein
A8O17_10820	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A8O17_10830	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A8O17_10840	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A8O17_10845	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
A8O17_10855	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A8O17_10860	ENOG4105CRQ	synthase (Component I)
A8O17_10865	ENOG4105KHN	chorismate mutase
A8O17_10870	ENOG4105D49	3-dehydroquinate synthase
A8O17_10875	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A8O17_10880	ENOG4105BZU	Histidine kinase
A8O17_10890	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A8O17_10895	ENOG4105EAH	synthase
A8O17_10900	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A8O17_10905	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
A8O17_10915	ENOG4105EUJ	GTP cyclohydrolase i
A8O17_10920	ENOG4105K70	DNA-binding protein
A8O17_10925	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
A8O17_10940	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A8O17_10945	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A8O17_10950	ENOG41065D1	
A8O17_10955	ENOG4105S2F	
A8O17_10970	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A8O17_10975	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A8O17_10980	ENOG4105CAT	Cytidine monophosphate kinase
A8O17_10995	ENOG4105MSI	germination protein ypeb
A8O17_11005	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
A8O17_11010	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
A8O17_11025	ENOG4107RGJ	metallophosphoesterase
A8O17_11040	ENOG4105I7S	Abortive infection protein
A8O17_11045	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A8O17_11050	ENOG4105T7X	
A8O17_11060	ENOG4108SAX	Membrane
A8O17_11065	ENOG4108JQ1	Dehydrogenase
A8O17_11070	ENOG4105FF2	Type I DHQase
A8O17_11085	ENOG4105BZU	Histidine kinase
A8O17_11090	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A8O17_11095	ENOG4105CRE	cytochrome C
A8O17_11100	ENOG4107TWT	Cytochrome c biogenesis protein
A8O17_11110	ENOG4105FE9	pseudouridine synthase
A8O17_11120	ENOG4108JIC	nucleoside recognition domain protein
A8O17_11125	ENOG4105DZ1	carboxypeptidase
A8O17_11135	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A8O17_11140	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A8O17_11155	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A8O17_11160	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A8O17_11165	ENOG4108R6K	riboflavin synthase, subunit alpha
A8O17_11170	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A8O17_11180	ENOG4105C3F	Signal peptidase i
A8O17_11185	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
A8O17_11210	ENOG4107ZE5	PPIases accelerate the folding of proteins
A8O17_11215	ENOG4105PTM	secreted protein
A8O17_11220	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A8O17_11230	ENOG4105G6R	Stage v sporulation protein ae
A8O17_11240	ENOG4105CZ3	stage V sporulation protein ad
A8O17_11245	ENOG41090VF	Stage v sporulation protein ac
A8O17_11260	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8O17_11265	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
A8O17_11270	ENOG41082AN	stage II sporulation protein
A8O17_11275	ENOG4105DZ1	carboxypeptidase
A8O17_11280	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A8O17_11285	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
A8O17_11290	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A8O17_11300	ENOG4105I3K	Ferric uptake regulator, Fur family
A8O17_11305	ENOG4105MZ9	stage II sporulation protein m
A8O17_11320	ENOG4105DFD	Na H antiporter
A8O17_11325	ENOG4108IJ0	Aspartate ammonia-lyase
A8O17_11330	ENOG4105HDK	L-asparaginase
A8O17_11335	ENOG4108IMY	Transcriptional regulator
A8O17_11345	ENOG4108YZ4	nudix hydrolase
A8O17_11355	ENOG4105CPC	Aldo Keto reductase
A8O17_11375	ENOG4106HZJ	
A8O17_11380	ENOG4105RHY	Pfam:UPF0157
A8O17_11385	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
A8O17_11390	ENOG4108XET	gCN5-related N-acetyltransferase
A8O17_11400	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A8O17_11410	ENOG4105E5W	Transporter
A8O17_11420	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
A8O17_11435	ENOG4108IXY	short-chain dehydrogenase reductase
A8O17_11440	ENOG41069FQ	Metallo-beta-lactamase superfamily
A8O17_11445	ENOG4105II7	pyrroline-5-carboxylate reductase
A8O17_11455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A8O17_11465	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A8O17_11470	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A8O17_11475	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A8O17_11480	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A8O17_11490	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
A8O17_11495	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
A8O17_11500	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A8O17_11505	ENOG4108HNZ	carboxyl transferase
A8O17_11510	ENOG4108ZVT	methylmalonyl-coA epimerase
A8O17_11520	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
A8O17_11525	ENOG4108QEG	Membrane
A8O17_11530	ENOG4105CDA	abc transporter atp-binding protein
A8O17_11535	ENOG4105E5Q	amino acid AbC transporter
A8O17_11540	ENOG4108HW3	(ABC) transporter
A8O17_11545	ENOG4108Y6J	UPF0403 protein
A8O17_11550	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
A8O17_11565	ENOG4105C7S	Dehydrogenase
A8O17_11570	ENOG4105CPP	Dehydrogenase, E1 component
A8O17_11585	ENOG4105CKM	Branched-chain carboxylic acid kinase
A8O17_11590	ENOG4107RDP	Dehydrogenase
A8O17_11600	ENOG4108JUB	Transcriptional regulator
A8O17_11605	ENOG4106CCJ	Protein of unknown function (DUF2627)
A8O17_11610	ENOG4105CR4	methylisocitrate lyase
A8O17_11615	ENOG4105DXD	2-methylcitrate dehydratase
A8O17_11625	ENOG4105C1G	acyl-Coa dehydrogenase
A8O17_11630	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A8O17_11640	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A8O17_11645	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A8O17_11660	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A8O17_11670	ENOG4107QQR	Sporulation
A8O17_11680	ENOG4105S1Z	Stage IV sporulation protein B
A8O17_11685	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A8O17_11690	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
A8O17_11695	ENOG4105DX0	Hemolysin A
A8O17_11705	ENOG4105CTB	Polyprenyl synthetase
A8O17_11710	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A8O17_11715	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A8O17_11720	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A8O17_11725	ENOG4105M7K	Involved in the transcription termination process (By similarity)
A8O17_11730	ENOG4108ZSR	alkaline shock protein
A8O17_11735	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A8O17_11755	ENOG410644B	Stage III sporulation protein af
A8O17_11765	ENOG4105KQ4	Stage iii sporulation protein ad
A8O17_11770	ENOG4108CQH	stage III sporulation protein AC
A8O17_11775	ENOG4105KR5	Stage iii sporulation protein
A8O17_11780	ENOG4105CD2	stage iii sporulation protein aa
A8O17_11790	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A8O17_11795	ENOG4105DC7	peptidase M24
A8O17_11800	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A8O17_11810	ENOG4105CBJ	Metal-dependent enzyme
A8O17_11825	ENOG4105KST	dependent repressor
A8O17_11830	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A8O17_11835	ENOG4105WZW	rhodanese family
A8O17_11840	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A8O17_11845	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A8O17_11850	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A8O17_11855	ENOG4105C0D	helicase
A8O17_11870	ENOG4108IMY	Transcriptional regulator
A8O17_11880	ENOG4105VFR	signal peptidase
A8O17_11945	ENOG4105C37	(CBS) domain
A8O17_11970	ENOG4105C5X	domain protein
A8O17_11995	ENOG4105E0M	Sulfatase
A8O17_12010	ENOG4107ZXI	Rhomboid family
A8O17_12020	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A8O17_12025	ENOG4105WDJ	50S ribosomal protein L33
A8O17_12045	ENOG41068DG	YceG-like family
A8O17_12050	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A8O17_12055	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A8O17_12060	ENOG4105E2Z	phosphate ABC transporter (Permease
A8O17_12065	ENOG4105C8U	phosphate abc transporter
A8O17_12070	ENOG4105CVA	phosphate
A8O17_12075	ENOG4107RF6	penicillin-binding protein
A8O17_12085	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A8O17_12090	ENOG4105SXS	Protein of unknown function (DUF456)
A8O17_12110	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A8O17_12115	ENOG41063Y9	
A8O17_12120	ENOG4108U5J	'-nucleotidase
A8O17_12125	ENOG4105N80	Ferric uptake regulator, Fur family
A8O17_12130	ENOG4108JYZ	YitT family
A8O17_12135	ENOG41069ZM	Protein of unknown function (DUF2624)
A8O17_12140	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A8O17_12155	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A8O17_12160	ENOG4105EGD	dinuclear metal center protein, YbgI family
A8O17_12175	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8O17_12180	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A8O17_12185	ENOG41082VT	Uncharacterized BCR, YaiI/YqxD family COG1671
A8O17_12190	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
A8O17_12200	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A8O17_12205	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
A8O17_12210	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
A8O17_12220	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A8O17_12225	ENOG4105KG3	cytidine deaminase
A8O17_12230	ENOG4107YR5	Diacylglycerol kinase
A8O17_12235	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A8O17_12240	ENOG4105CTJ	Metal Dependent Phosphohydrolase
A8O17_12250	ENOG4105C9A	Phoh family
A8O17_12255	ENOG4105EI1	sporulation protein yqfd
A8O17_12260	ENOG41068P3	sporulation protein YqfC
A8O17_12270	ENOG4105DI5	UPF0365 protein
A8O17_12275	ENOG4105F7J	membrane-bound serine protease
A8O17_12280	ENOG4105KTH	gatB Yqey
A8O17_12295	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A8O17_12300	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A8O17_12305	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A8O17_12315	ENOG4105CFG	Acts as a chaperone (By similarity)
A8O17_12320	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A8O17_12325	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A8O17_12330	ENOG4105CSA	Coproporphyrinogen iii oxidase
A8O17_12335	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A8O17_12345	ENOG4108ZRV	stage ii sporulation protein p
A8O17_12350	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
A8O17_12355	ENOG41082YS	Binds directly to 16S ribosomal RNA
A8O17_12360	ENOG4105TQK	DNA polymerase iii, delta' subunit
A8O17_12370	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
A8O17_12375	ENOG4108UK2	deaminase
A8O17_12380	ENOG4105KQC	Competence protein
A8O17_12390	ENOG4108D32	Methyltransferase
A8O17_12400	ENOG4108WF2	Metal Dependent Phosphohydrolase
A8O17_12405	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A8O17_12410	ENOG410812S	Rna-binding protein
A8O17_12415	ENOG4105E2X	shikimate dehydrogenase
A8O17_12420	ENOG4105CQW	ribosome biogenesis GTPase YqeH
A8O17_12425	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
A8O17_12445	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
A8O17_12450	ENOG41080BT	SNARE associated Golgi
A8O17_12465	ENOG4105WFK	nuclease
A8O17_12470	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8O17_12475	ENOG4107Y5K	Resolvase
A8O17_12480	ENOG4108UXE	Protein tyrosine phosphatase
A8O17_12505	ENOG4108SWU	Histidine kinase
A8O17_12510	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A8O17_12515	ENOG4105DHF	Membrane
A8O17_12525	ENOG4108UYN	gCN5-related N-acetyltransferase
A8O17_12530	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A8O17_12535	ENOG41068VA	
A8O17_12540	ENOG41087NI	Sulfite exporter TauE/SafE
A8O17_12545	ENOG4105VFE	sira family
A8O17_12550	ENOG4107TPS	domain protein
A8O17_12560	ENOG4105VFE	sira family
A8O17_12565	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
A8O17_12570	ENOG4105XTG	Pfam:DUF156
A8O17_12575	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
A8O17_12590	ENOG41090E6	transcriptional regulator MERR family
A8O17_12605	ENOG4105C37	(CBS) domain
A8O17_12620	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
A8O17_12625	ENOG4105H3G	oxidoreductase
A8O17_12630	ENOG4105PGM	cation diffusion facilitator family transporter
A8O17_12635	ENOG41090U3	tautomerase
A8O17_12655	ENOG4105KMT	branched-chain amino acid
A8O17_12660	ENOG4108UMN	azlc family
A8O17_12665	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
A8O17_12670	ENOG41067XF	inhibitor
A8O17_12690	ENOG41064BW	Protein of unknown function (DUF2568)
A8O17_12700	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
A8O17_12705	ENOG4105EA8	2-Nitropropane dioxygenase
A8O17_12710	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A8O17_12725	ENOG4108MEK	Metal-binding protein YodA
A8O17_12730	ENOG410904A	RNA polymerase
A8O17_12735	ENOG4105CPC	Aldo Keto reductase
A8O17_12745	ENOG4108KAM	Transcriptional regulator
A8O17_12750	ENOG4105C7F	AcnD-accessory protein PrpF
A8O17_12755	ENOG41083Q9	chitosanase
A8O17_12760	ENOG4105X5K	response regulator receiver protein
A8O17_12765	ENOG4108VQT	Alpha beta hydrolase fold protein
A8O17_12770	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
A8O17_12775	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
A8O17_12780	ENOG4105Z0X	Glyoxalase Bleomycin resistance protein (Dioxygenase
A8O17_12790	ENOG4105PGS	Spore coat protein
A8O17_12795	ENOG4105E2A	Dehydrogenase
A8O17_12810	ENOG4105VUF	Transcriptional regulator
A8O17_12820	ENOG4105DQ4	alcohol dehydrogenase
A8O17_12825	ENOG4108Z0Z	intracellular protease Pfpi family
A8O17_12830	ENOG4108HKT	sucrose-6-phosphate hydrolase
A8O17_12835	ENOG4105F3R	pts system mannose fructose sorbose family iid
A8O17_12840	ENOG4105ETZ	PTS System
A8O17_12845	ENOG4108IQ3	PTS system
A8O17_12850	ENOG4105YHU	PTS system
A8O17_12855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A8O17_12860	ENOG4105C85	amino acid
A8O17_12865	ENOG4105N14	lysine exporter protein LysE YggA
A8O17_12870	ENOG4108NGU	Transcriptional regulator
A8O17_12875	ENOG4105JVQ	RNA Polymerase
A8O17_12880	ENOG4108P49	AntiSigma factor
A8O17_12885	ENOG4105EXC	Acyl-transferase
A8O17_12890	ENOG4105WDR	
A8O17_12895	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A8O17_12900	ENOG41082JN	Transcriptional regulator
A8O17_12915	ENOG4105TMB	Formate nitrite transporter
A8O17_12920	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
A8O17_12925	ENOG4108JB9	formate dehydrogenase
A8O17_12940	ENOG4105C28	cystathionine
A8O17_12955	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
A8O17_12970	ENOG4107XRG	penicillin-binding protein
A8O17_12975	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A8O17_12980	ENOG4105DBI	uridine monophosphokinase
A8O17_12985	ENOG4105CFP	Peptidase U32
A8O17_12990	ENOG4105XYU	peptidase (U32 family)
A8O17_12995	ENOG4108VQJ	O-methyltransferase
A8O17_13000	ENOG4105HHA	aminodeoxychorismate lyase
A8O17_13005	ENOG4105VPH	UPF0473 protein
A8O17_13010	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A8O17_13015	ENOG4105VBH	UPF0297 protein
A8O17_13020	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A8O17_13025	ENOG4105C02	permease
A8O17_13030	ENOG4105CDA	abc transporter atp-binding protein
A8O17_13035	ENOG4105CT1	(ABC) transporter
A8O17_13040	ENOG4105EAD	ABC transporter
A8O17_13045	ENOG4105DRP	amino acid AbC transporter
A8O17_13055	ENOG41060CR	
A8O17_13065	ENOG4105C7H	Helicase, RecD TraA family
A8O17_13075	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A8O17_13080	ENOG4105C3J	Cysteine desulfurase
A8O17_13090	ENOG4105D1H	recombination factor protein RarA
A8O17_13095	ENOG4105CUZ	uba thif-type nad fad binding protein
A8O17_13105	ENOG4105C9M	aspartyl-trna synthetase
A8O17_13110	ENOG4105CUT	histidyl-tRNA synthetase
A8O17_13120	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A8O17_13130	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A8O17_13135	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A8O17_13140	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A8O17_13145	ENOG41067VP	Protein of unknown function (DUF1049)
A8O17_13150	ENOG4105NCW	Trka-c domain protein
A8O17_13155	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A8O17_13165	ENOG4105CKP	Polysaccharide Biosynthesis Protein
A8O17_13170	ENOG4108QG2	Membrane
A8O17_13175	ENOG4105NAP	
A8O17_13180	ENOG4105VIE	preprotein translocase, subunit YajC
A8O17_13185	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A8O17_13190	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A8O17_13195	ENOG41061AI	Protein of unknown function (DUF2905)
A8O17_13200	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A8O17_13205	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A8O17_13215	ENOG4105IE8	Alpha-ketoglutarate permease
A8O17_13220	ENOG4105CK5	oxidoreductase
A8O17_13245	ENOG4105BZG	amino acid carrier protein
A8O17_13250	ENOG4105CDY	transcriptional regulatory protein
A8O17_13260	ENOG4106678	morphogenetic protein associated with SpoVID
A8O17_13265	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A8O17_13270	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A8O17_13275	ENOG4108IYU	L-aspartate oxidase
A8O17_13290	ENOG4105CQC	Prephenate dehydratase
A8O17_13295	ENOG41090I5	UPF0735 ACT domain-containing protein
A8O17_13300	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A8O17_13315	ENOG4105K46	50S ribosomal protein l27
A8O17_13320	ENOG4105X36	(ribosomal) protein
A8O17_13325	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A8O17_13340	ENOG4107QMS	site-determining protein
A8O17_13345	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
A8O17_13350	ENOG4105YHC	Rod shape-determining protein MreD
A8O17_13355	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A8O17_13360	ENOG4105DFF	Rod shape-determining protein mreb
A8O17_13365	ENOG4105W5Q	DNA repair protein (RadC
A8O17_13370	ENOG4108Z03	MAF-like protein
A8O17_13380	ENOG4106A3R	peptidase
A8O17_13385	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A8O17_13390	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A8O17_13400	ENOG4106AR7	Spore coat protein
A8O17_13405	ENOG41068KH	stage VI sporulation protein D
A8O17_13410	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A8O17_13415	ENOG4105D52	delta-aminolevulinic acid dehydratase
A8O17_13425	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A8O17_13435	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A8O17_13445	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A8O17_13450	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A8O17_13455	ENOG4108IUQ	atp-dependent protease
A8O17_13460	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A8O17_13465	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A8O17_13475	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A8O17_13480	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A8O17_13485	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A8O17_13490	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A8O17_13495	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A8O17_13500	ENOG4108ZP8	Acetolactate synthase small subunit
A8O17_13505	ENOG4105C7K	acetolactate synthase
A8O17_13515	ENOG4105I4A	GCN5-related N-acetyltransferase
A8O17_13525	ENOG4107KM7	Heat induced stress protein YflT
A8O17_13535	ENOG4105M59	Phosphodiesterase, mj0936 family
A8O17_13540	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A8O17_13545	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A8O17_13550	ENOG4108XJQ	germination protein
A8O17_13555	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A8O17_13560	ENOG41067TZ	transcriptional regulator, MarR family
A8O17_13565	ENOG4105PFC	Transcriptional regulator
A8O17_13575	ENOG4105E33	succinate dehydrogenase
A8O17_13585	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
A8O17_13600	ENOG4105CFH	Aspartokinase
A8O17_13605	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A8O17_13610	ENOG4105K63	Thioredoxin
A8O17_13615	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
A8O17_13620	ENOG4105C10	Electron transfer flavoprotein
A8O17_13625	ENOG4105BZJ	Electron transfer flavoprotein
A8O17_13630	ENOG41060WC	Enoyl-CoA hydratase
A8O17_13635	ENOG4107Z3H	Transcriptional regulator, TetR family
A8O17_13640	ENOG4105CEY	Amp-dependent synthetase and ligase
A8O17_13650	ENOG4105C98	muts2 protein
A8O17_13655	ENOG4105DCG	PHP domain protein
A8O17_13670	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A8O17_13675	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A8O17_13680	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A8O17_13690	ENOG4108RWN	rrna methyltransferase
A8O17_13695	ENOG41067MF	small acid-soluble spore protein
A8O17_13705	ENOG4105CQB	FAD linked oxidase domain protein
A8O17_13710	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A8O17_13730	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
A8O17_13735	ENOG4105DRS	transport system, permease
A8O17_13750	ENOG4108MDK	Dehydrogenase
A8O17_13760	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
A8O17_13765	ENOG4105EF1	ribulokinase
A8O17_13775	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
A8O17_13780	ENOG4105CN9	Peptidase m42 family protein
A8O17_13790	ENOG410696E	Membrane
A8O17_13795	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A8O17_13800	ENOG4105VJV	50s ribosomal protein L35
A8O17_13805	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A8O17_13815	ENOG41067MG	lrgb family
A8O17_13825	ENOG4105DY9	regulatoR
A8O17_13830	ENOG4108HRK	Histidine kinase
A8O17_13835	ENOG4105U0R	haloacid dehalogenase-like hydrolase
A8O17_13840	ENOG4105C22	threonyL-tRNA synthetase
A8O17_13845	ENOG4108TDW	sporulation protein YtxC
A8O17_13865	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A8O17_13870	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A8O17_13875	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A8O17_13880	ENOG4105KVH	Transcriptional regulator
A8O17_13885	ENOG4105F27	Major Facilitator
A8O17_13890	ENOG4105CV8	reductase
A8O17_13895	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A8O17_13910	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A8O17_13915	ENOG4105C2M	dna polymerase I
A8O17_13920	ENOG4105BZU	Histidine kinase
A8O17_13925	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A8O17_13930	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A8O17_13935	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A8O17_13940	ENOG4105BZN	citrate synthase
A8O17_13950	ENOG4108REF	Sporulation integral membrane protein ytvi
A8O17_13955	ENOG4105FS0	cytoplasmic membrane protein
A8O17_13960	ENOG4105CA9	Pyruvate kinase
A8O17_13965	ENOG4105CTQ	phosphohexokinase
A8O17_13975	ENOG4108IEY	Carboxyl transferase domain
A8O17_13980	ENOG4105C6K	Malic enzyme
A8O17_13985	ENOG4105C0B	DNA polymerase III (alpha subunit)
A8O17_13990	ENOG4105VV2	
A8O17_14000	ENOG4106EVM	
A8O17_14005	ENOG4105SFS	phosphoesterase RecJ domain protein
A8O17_14025	ENOG410635A	Membrane
A8O17_14030	ENOG4105CH2	amidohydrolase
A8O17_14050	ENOG4105DEN	Luciferase family
A8O17_14055	ENOG4105CDA	abc transporter atp-binding protein
A8O17_14080	ENOG4108XSB	acetyltransferase, (GNAT) family
A8O17_14085	ENOG4108KSA	LysR family transcriptional regulator
A8O17_14090	ENOG4105E8R	UPF0173 metal-dependent hydrolase
A8O17_14105	ENOG4105CH7	arginosuccinase
A8O17_14110	ENOG4105CDH	Citrulline--aspartate ligase
A8O17_14115	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A8O17_14120	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A8O17_14130	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A8O17_14135	ENOG4105KBJ	sporulation protein ytfj
A8O17_14145	ENOG4105VK3	rdd domain containing protein
A8O17_14150	ENOG4105D07	Signal peptide peptidase, SppA
A8O17_14155	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A8O17_14160	ENOG4105EFZ	amidohydrolase
A8O17_14165	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A8O17_14200	ENOG4105U5Y	Transcriptional regulator
A8O17_14210	ENOG4105BZU	Histidine kinase
A8O17_14215	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A8O17_14225	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A8O17_14235	ENOG4105F1V	Acetoin utilization protein
A8O17_14240	ENOG4105W87	Cbs domain
A8O17_14245	ENOG4105DGU	Histone deacetylase
A8O17_14250	ENOG4105ER2	Ompa motb domain protein
A8O17_14255	ENOG4107R0U	MotA TolQ exbB proton channel
A8O17_14260	ENOG4105ETE	Transcriptional regulator (LacI family
A8O17_14265	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A8O17_14285	ENOG4105DFU	Cell wall formation (By similarity)
A8O17_14295	ENOG4108VDD	TRNA binding domain protein
A8O17_14310	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
A8O17_14325	ENOG4105C6K	Malic enzyme
A8O17_14330	ENOG4105C8F	Beta-lactamase domain protein
A8O17_14335	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A8O17_14345	ENOG4108V15	phosphotransferase enzyme family
A8O17_14350	ENOG4108IUM	Glycogen debranching enzyme
A8O17_14365	ENOG4107F58	2'-5' rna ligase
A8O17_14370	ENOG4105C6T	cysteine synthase
A8O17_14375	ENOG4107QSE	Dipeptidase
A8O17_14380	ENOG4105C7N	Xanthine uracil vitamin C permease
A8O17_14395	ENOG4105YW5	deoR family transcriptional regulator
A8O17_14410	ENOG4105CBX	hi0933 family
A8O17_14415	ENOG4105C94	Transporter
A8O17_14425	ENOG4105MU9	integral membrane protein
A8O17_14430	ENOG4105DDC	Oxidoreductase domain protein
A8O17_14440	ENOG4105F5H	Glycosyl Hydrolase Family 88
A8O17_14450	ENOG41075H3	AraC family transcriptional regulator
A8O17_14460	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A8O17_14470	ENOG4106A3M	Cytochrome p-450
A8O17_14475	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A8O17_14480	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A8O17_14485	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A8O17_14490	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A8O17_14495	ENOG4108W8G	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity)
A8O17_14500	ENOG4105NTD	Inherit from COG: Hydrolase
A8O17_14515	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
A8O17_14520	ENOG4105I1K	ABC transporter
A8O17_14530	ENOG41085GJ	domain protein
A8O17_14535	ENOG4105C8T	Leucyl-tRNA synthetase
A8O17_14545	ENOG4105BZU	Histidine kinase
A8O17_14550	ENOG410605W	Major Facilitator
A8O17_14555	ENOG4106UBQ	
A8O17_14565	ENOG4105C19	ABC transporter
A8O17_14570	ENOG4105EWM	Histidine kinase
A8O17_14580	ENOG4107R34	abc transporter permease protein
A8O17_14585	ENOG4105C19	ABC transporter
A8O17_14600	ENOG4105DVE	abc transporter atp-binding protein
A8O17_14605	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
A8O17_14620	ENOG4105N5T	Radical SAM Protein
A8O17_14635	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
A8O17_14640	ENOG4108Z0R	Transferase
A8O17_14645	ENOG4105C85	amino acid
A8O17_14650	ENOG4105CAQ	asparagine synthetase
A8O17_14655	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A8O17_14660	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A8O17_14675	ENOG4105D2X	ABC transporter substrate-binding protein
A8O17_14685	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
A8O17_14700	ENOG4108RMU	ferritin dps family protein
A8O17_14715	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
A8O17_14720	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A8O17_14725	ENOG4108V2W	Carbonate dehydratase
A8O17_14750	ENOG4105CC5	ABC transporter
A8O17_14755	ENOG4105CC5	ABC transporter
A8O17_14760	ENOG4105DIK	(ABC) transporter
A8O17_14765	ENOG4105DSE	periplasmic solute binding protein
A8O17_14770	ENOG4105DTQ	mandelate racemase muconate lactonizing
A8O17_14775	ENOG4105CEY	Amp-dependent synthetase and ligase
A8O17_14780	ENOG4108IPT	Naphthoate synthase
A8O17_14785	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
A8O17_14790	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A8O17_14795	ENOG4105E4F	Isochorismate synthase
A8O17_14815	ENOG4108IAJ	Nad-dependent epimerase dehydratase
A8O17_14820	ENOG4107SBE	Glycosyl transferase (Group 1
A8O17_14835	ENOG4107SBE	Glycosyl transferase (Group 1
A8O17_14840	ENOG4108KS4	Spore coat protein
A8O17_14855	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A8O17_14865	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A8O17_15000	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
A8O17_15005	ENOG4105VRR	gCN5-related N-acetyltransferase
A8O17_15010	ENOG4105DZ6	Band 7 protein
A8O17_15020	ENOG4106DF1	
A8O17_15025	ENOG4108VNY	MOSC domain protein
A8O17_15030	ENOG4108JB8	alcohol dehydrogenase
A8O17_15035	ENOG4105C26	Dehydrogenase
A8O17_15040	ENOG4105TRT	Transcriptional regulator
A8O17_15055	ENOG4105CZN	Potassium uptake protein
A8O17_15060	ENOG4107I77	yiaA/B two helix domain
A8O17_15065	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A8O17_15085	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A8O17_15095	ENOG4105EE0	oxidoreductase
A8O17_15100	ENOG4105DKG	l-rhamnose isomerase
A8O17_15105	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
A8O17_15110	ENOG4105DET	Rhamnulokinase
A8O17_15115	ENOG4105E98	transcriptional regulator DeoR family
A8O17_15125	ENOG4105C8Q	Methyl-accepting chemotaxis
A8O17_15130	ENOG4105C8Q	Methyl-accepting chemotaxis
A8O17_15135	ENOG4105C8Q	Methyl-accepting chemotaxis
A8O17_15140	ENOG4105C8Q	Methyl-accepting chemotaxis
A8O17_15155	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A8O17_15165	ENOG4105C37	(CBS) domain
A8O17_15180	ENOG4107PBV	potassium channel
A8O17_15185	ENOG4107PBV	potassium channel
A8O17_15200	ENOG4107QYV	phosphohexose isomerase
A8O17_15210	ENOG4107QW4	alcohol dehydrogenase
A8O17_15215	ENOG4105WG9	Conserved Protein
A8O17_15225	ENOG4105CHM	Aminotransferase
A8O17_15230	ENOG4108ZB6	transcriptional regulator AsnC family
A8O17_15235	ENOG4108MUZ	hydrolase
A8O17_15245	ENOG4105C87	Aminotransferase class I and II
A8O17_15250	ENOG4108HGU	Histidine kinase
A8O17_15255	ENOG4105Y38	Kinase-associated protein B
A8O17_15275	ENOG4105BZ4	penicillin-binding protein
A8O17_15280	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
A8O17_15295	ENOG4108MRH	transcriptional regulatory protein
A8O17_15300	ENOG4105DIH	basic membrane
A8O17_15305	ENOG4108JQ9	ABC transporter
A8O17_15310	ENOG4105UIB	(ABC) transporter
A8O17_15330	ENOG4105D65	subunit l
A8O17_15335	ENOG4105HC0	Na H antiporter
A8O17_15340	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A8O17_15345	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A8O17_15350	ENOG4105SC1	monovalent cation H antiporter subunit E
A8O17_15360	ENOG4105KJM	monovalent cation h antiporter subunit g
A8O17_15365	ENOG4105KA0	thioesterase Superfamily protein
A8O17_15375	ENOG4105BZU	Histidine kinase
A8O17_15400	ENOG4105D58	Diguanylate phosphodiesterase
A8O17_15405	ENOG4105DAP	Nicotinate phosphoribosyltransferase
A8O17_15430	ENOG4105C02	permease
A8O17_15450	ENOG410904N	short-chain dehydrogenase reductase
A8O17_15485	ENOG4108K8K	Transcriptional regulator
A8O17_15490	ENOG4105DCF	alanine dehydrogenase
A8O17_15500	ENOG4105WQT	MbtH domain protein
A8O17_15505	ENOG4105CEY	Amp-dependent synthetase and ligase
A8O17_15510	ENOG4105WQI	isochorismatase
A8O17_15515	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A8O17_15520	ENOG4105E4F	Isochorismate synthase
A8O17_15525	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A8O17_15530	ENOG4105NIV	Esterase
A8O17_15550	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A8O17_15560	ENOG41069ER	domain protein
A8O17_15575	ENOG4105CEP	NADH dehydrogenase
A8O17_15580	ENOG4105CAY	ferredoxin--nadp reductase
A8O17_15600	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
A8O17_15605	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A8O17_15620	ENOG4105ZKE	UPF0349 protein
A8O17_15635	ENOG41083MR	nifu domain-containing protein
A8O17_15640	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A8O17_15645	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A8O17_15650	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A8O17_15655	ENOG4105D6E	homoserine dehydrogenase
A8O17_15665	ENOG4108W5N	phosphatidylglycerophosphatase a
A8O17_15670	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A8O17_15680	ENOG4105MMD	transcriptional regulator
A8O17_15685	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
A8O17_15690	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A8O17_15695	ENOG4105FAA	peptidase M23
A8O17_15700	ENOG4108YTE	sporulation protein YunB
A8O17_15705	ENOG4105KZD	Domain of unknown function (DUF1805)
A8O17_15710	ENOG4107R8B	5'-nucleotidase
A8O17_15720	ENOG4105I3N	Conserved Protein
A8O17_15730	ENOG4105CD3	dihydroorotase
A8O17_15735	ENOG4105G9B	Transcriptional regulator
A8O17_15750	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
A8O17_15755	ENOG4105VT2	5-hydroxyisourate hydrolase
A8O17_15765	ENOG4107YV9	domain protein
A8O17_15770	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A8O17_15785	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
A8O17_15790	ENOG4105C5R	Aminotransferase
A8O17_15805	ENOG4108K8S	endonuclease I
A8O17_15810	ENOG4108IJ9	(ABC) transporter
A8O17_15815	ENOG4105FDP	GntR family transcriptional regulator
A8O17_15820	ENOG4108KPW	sugar kinase
A8O17_15825	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A8O17_15830	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
A8O17_15835	ENOG4105XN3	extracellular solute-binding protein family 1
A8O17_15840	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
A8O17_15845	ENOG4105PKS	Excinuclease abc c subunit domain protein
A8O17_15850	ENOG4107VFR	oxidoreductase
A8O17_15865	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
A8O17_15870	ENOG4105NPE	arsR family transcriptional regulator
A8O17_15875	ENOG4105DIW	FeS assembly protein SUFB
A8O17_15880	ENOG4108UNV	SUF system FeS assembly protein, NifU family
A8O17_15885	ENOG4105C9B	Cysteine desulfurase
A8O17_15890	ENOG4105JRK	feS assembly protein SufD
A8O17_15895	ENOG4105C3K	feS assembly ATPase SufC
A8O17_15910	ENOG4105D01	(LipO)protein
A8O17_15915	ENOG4108UMI	ABC transporter, permease
A8O17_15920	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A8O17_15945	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A8O17_15950	ENOG41080E8	Transcriptional regulator, Spx MgsR family
A8O17_15955	ENOG4105C1G	acyl-Coa dehydrogenase
A8O17_15960	ENOG4105CHU	acetyl-coa acetyltransferase
A8O17_15990	ENOG41067TZ	transcriptional regulator, MarR family
A8O17_15995	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A8O17_16000	ENOG4105MDS	4-oxalocrotonate tautomerase
A8O17_16015	ENOG4105EGI	Transcriptional regulator
A8O17_16025	ENOG4105E0A	ABC, transporter
A8O17_16045	ENOG4105E1F	short-chain dehydrogenase reductase
A8O17_16050	ENOG4105HUF	DNA protection during starvation protein
A8O17_16055	ENOG4105C0H	protease
A8O17_16065	ENOG4105F3H	Histidine kinase
A8O17_16075	ENOG41067SE	Tetr family transcriptional regulator
A8O17_16080	ENOG4105C9Q	fumarate hydratase class II
A8O17_16105	ENOG4105WH1	Two component transcriptional regulator luxr family
A8O17_16110	ENOG4105ENE	Histidine kinase
A8O17_16125	ENOG41087YS	Phage shock protein A
A8O17_16140	ENOG4108WBT	adenosyltransferase
A8O17_16145	ENOG4105E0A	ABC, transporter
A8O17_16150	ENOG4105EHG	Permease protein
A8O17_16155	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A8O17_16160	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A8O17_16165	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
A8O17_16175	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A8O17_16185	ENOG4106DF4	Sigma-70, region 4
A8O17_16195	ENOG4105F0F	Oxalate decarboxylase
A8O17_16205	ENOG4107RBB	ABC transporter, permease
A8O17_16210	ENOG4105C19	ABC transporter
A8O17_16215	ENOG4108WMK	Efflux transporter RND family MFP subunit
A8O17_16220	ENOG4105E0A	ABC, transporter
A8O17_16225	ENOG4105EHG	Permease protein
A8O17_16230	ENOG4105DQ5	transport system permease protein
A8O17_16245	ENOG4105D5Q	Arginine ornithine antiporter
A8O17_16255	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
A8O17_16260	ENOG4107QZ2	Sulfatase
A8O17_16265	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
A8O17_16270	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A8O17_16275	ENOG4105E0C	molybdate abc transporter
A8O17_16290	ENOG4105EEQ	Na H antiporter
A8O17_16295	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A8O17_16300	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A8O17_16305	ENOG4105EEM	helicase
A8O17_16310	ENOG4105EN6	Membrane
A8O17_16320	ENOG4107ZQN	disulfide bond
A8O17_16325	ENOG4105C59	p-type ATPase
A8O17_16330	ENOG4105C59	p-type ATPase
A8O17_16335	ENOG410681U	heavy metal transport detoxification protein
A8O17_16340	ENOG4105VPX	protein, conserved in bacteria
A8O17_16345	ENOG4105D9R	oxidoreductase
A8O17_16350	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A8O17_16355	ENOG4105ME7	Membrane
A8O17_16360	ENOG4105RXJ	
A8O17_16365	ENOG4105KPY	Small multidrug resistance protein
A8O17_16370	ENOG4105KBX	Transcriptional regulator, TetR family
A8O17_16375	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A8O17_16385	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A8O17_16390	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A8O17_16400	ENOG4105XZU	Preprotein translocase, subunit SecG
A8O17_16425	ENOG4105KVH	Transcriptional regulator
A8O17_16430	ENOG4105C8Q	Methyl-accepting chemotaxis
A8O17_16435	ENOG4105R40	Glycine betaine carnitine choline
A8O17_16440	ENOG4108HQR	Glycine betaine
A8O17_16445	ENOG4105E90	ABC transporter
A8O17_16450	ENOG4108IJ8	ABC transporter
A8O17_16455	ENOG4107HG4	Transcriptional regulator
A8O17_16465	ENOG4105H5S	
A8O17_16480	ENOG41082BM	Transcriptional regulator, arsr family
A8O17_16485	ENOG4105R40	Glycine betaine carnitine choline
A8O17_16490	ENOG4108HQR	Glycine betaine
A8O17_16495	ENOG4105E90	ABC transporter
A8O17_16500	ENOG4108IJ8	ABC transporter
A8O17_16505	ENOG4107HG4	Transcriptional regulator
A8O17_16510	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A8O17_16515	ENOG4108QCI	YvbH-like oligomerisation region
A8O17_16525	ENOG4105T65	Membrane-associated protein
A8O17_16530	ENOG4108W0I	acetyltransferase
A8O17_16535	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A8O17_16540	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A8O17_16545	ENOG4105CP7	Triose-phosphate isomerase
A8O17_16550	ENOG4105BZA	Phosphoglycerate kinase
A8O17_16560	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A8O17_16575	ENOG4105CMD	Transcriptional regulator, GntR family
A8O17_16580	ENOG4105DEN	Luciferase family
A8O17_16585	ENOG4105GZI	Transcriptional regulator
A8O17_16590	ENOG4107RT3	EamA-like transporter family
A8O17_16600	ENOG4105VRS	hydrolase family 18
A8O17_16605	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
A8O17_16610	ENOG4107QR9	Iron-sulfur cluster binding protein
A8O17_16615	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A8O17_16625	ENOG4105BZU	Histidine kinase
A8O17_16630	ENOG4105KCT	ABC transporter
A8O17_16635	ENOG4108M15	ABC transporter
A8O17_16640	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
A8O17_16645	ENOG4108MJI	response regulator
A8O17_16660	ENOG4105EG2	ABC transporter, permease
A8O17_16670	ENOG4107FKK	extracellular solute-binding protein family 1
A8O17_16680	ENOG4105JXH	GntR family transcriptional regulator
A8O17_16685	ENOG4105DAA	L-lactate
A8O17_16690	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A8O17_16700	ENOG4108ZPC	Polysaccharide pyruvyl transferase
A8O17_16705	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A8O17_16710	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
A8O17_16715	ENOG4105D3Q	Sugar transferase
A8O17_16725	ENOG4105K64	Glycosyl transferase, family 2
A8O17_16735	ENOG4107QRS	glycosyltransferase group 2 family protein
A8O17_16740	ENOG41068W6	Capsular polysaccharide biosynthesis protein
A8O17_16745	ENOG4108KMV	Glycosyl transferase (Group 1
A8O17_16750	ENOG4105K64	Glycosyl transferase, family 2
A8O17_16755	ENOG4108PQP	glycosyl transferase group 1
A8O17_16765	ENOG4108QV3	biosynthesis protein
A8O17_16770	ENOG4105HTX	biosynthesis protein
A8O17_16780	ENOG4105EBR	Carboxylesterase
A8O17_16790	ENOG4105PY6	Phenolic acid decarboxylase
A8O17_16795	ENOG4105NI3	Protein of unknown function (DUF3237)
A8O17_16805	ENOG4105FQP	Beta-lactamase
A8O17_16810	ENOG4105EDQ	levansucrase EC 2.4.1.10
A8O17_16815	ENOG4108HKT	sucrose-6-phosphate hydrolase
A8O17_16820	ENOG4107QTZ	amino acid
A8O17_16845	ENOG4105DNP	FAD linked oxidase domain protein
A8O17_16850	ENOG4105IRW	patatin-like phospholipase family protein
A8O17_16860	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A8O17_16865	ENOG4107URF	beta-phospho-glucomutase
A8O17_16870	ENOG4105CG3	alpha amylase, catalytic region
A8O17_16885	ENOG4105EG2	ABC transporter, permease
A8O17_16890	ENOG4105D56	permease protein
A8O17_16895	ENOG4107FKK	extracellular solute-binding protein family 1
A8O17_16900	ENOG4108IUK	alpha amylase, catalytic
A8O17_16905	ENOG4105FKQ	transcriptional regulator
A8O17_16910	ENOG4108URH	decarboxylase
A8O17_16915	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
A8O17_16920	ENOG4105CHH	sulfate transporter
A8O17_16925	ENOG4108V2W	Carbonate dehydratase
A8O17_16930	ENOG4105C5I	Dehydrogenase
A8O17_16940	ENOG4105C19	ABC transporter
A8O17_16945	ENOG4105EWM	Histidine kinase
A8O17_16955	ENOG4107A6P	
A8O17_16960	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
A8O17_16965	ENOG4105KRI	phosphocarrier protein (HPr
A8O17_16970	ENOG4105CIE	May be required for sporulation (By similarity)
A8O17_16975	ENOG4105CHW	UPF0052 protein
A8O17_16980	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A8O17_16985	ENOG4108Z4K	mutator MutT protein
A8O17_16990	ENOG4105C3M	thioredoxin reductase
A8O17_17005	ENOG4105BZ1	(ABC) transporter
A8O17_17015	ENOG4106FGC	
A8O17_17025	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A8O17_17030	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A8O17_17035	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A8O17_17040	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A8O17_17045	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A8O17_17050	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A8O17_17055	ENOG4107RN8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A8O17_17060	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
A8O17_17070	ENOG4108E16	pectate lyase
A8O17_17075	ENOG4108S4C	acetyltransferase
A8O17_17080	ENOG4107XGZ	Hydrolase
A8O17_17085	ENOG4105HKU	nucleoside recognition domain-containing protein
A8O17_17090	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A8O17_17095	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A8O17_17100	ENOG4105CE4	GlcNAc 6-P deacetylase
A8O17_17105	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A8O17_17110	ENOG4105FDP	GntR family transcriptional regulator
A8O17_17115	ENOG41088CQ	domain protein
A8O17_17125	ENOG4106A3M	Cytochrome p-450
A8O17_17130	ENOG410625E	
A8O17_17145	ENOG41086DT	Membrane protein of unknown function
A8O17_17150	ENOG41067S9	phage shock protein C, PspC
A8O17_17155	ENOG4108PY7	
A8O17_17175	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A8O17_17180	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A8O17_17195	ENOG4105MKU	Transcriptional regulator
A8O17_17215	ENOG4105CN1	protease
A8O17_17220	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A8O17_17225	ENOG4105CAK	Cell division ATP-binding protein ftsE
A8O17_17240	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A8O17_17250	ENOG4105MS2	ribosomal subunit Interface protein
A8O17_17265	ENOG4105MQ3	flagellar protein FliS
A8O17_17270	ENOG4107RT6	flagellar hook-associated
A8O17_17275	ENOG41083S7	flagellar protein FlaG
A8O17_17280	ENOG4105I03	Flagellin
A8O17_17285	ENOG41085Y9	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A8O17_17290	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
A8O17_17295	ENOG4105MKD	
A8O17_17300	ENOG4105DTJ	flagellar hook-associated protein
A8O17_17305	ENOG4105E1Q	flagellar hook-associated protein
A8O17_17320	ENOG4105RU3	
A8O17_17325	ENOG41081UC	Inherit from COG: Competence protein
A8O17_17345	ENOG4105WH1	Two component transcriptional regulator luxr family
A8O17_17350	ENOG4105BZU	Histidine kinase
A8O17_17355	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A8O17_17360	ENOG4108KGH	TRANSCRIPTIONal
A8O17_17365	ENOG4105ESV	Glycosyl transferase, family 4
A8O17_17370	ENOG4107EF8	Glycosyl transferase (Group 1
A8O17_17385	ENOG4105QZI	O-Antigen Polymerase
A8O17_17390	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A8O17_17395	ENOG4107RA4	Glycosyl transferase (Group 1
A8O17_17400	ENOG4105PSV	Polysaccharide Biosynthesis Protein
A8O17_17405	ENOG4105D3Q	Sugar transferase
A8O17_17410	ENOG4105D3Q	Sugar transferase
A8O17_17415	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A8O17_17420	ENOG4105JFG	SpoIID LytB domain protein
A8O17_17435	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A8O17_17440	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A8O17_17445	ENOG4107VDP	teichoic acid biosynthesis
A8O17_17450	ENOG41088M2	Glycosyl transferase family 2
A8O17_17465	ENOG4105EY8	ABC transporter
A8O17_17475	ENOG4107SJB	teichoic acid biosynthesis
A8O17_17480	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
A8O17_17485	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
A8O17_17495	ENOG4107RZX	Teichoic acid biosynthesis protein
A8O17_17500	ENOG410651K	Teichoic acid biosynthesis protein C
A8O17_17510	ENOG4105DG6	mannose-6-phosphate isomerase
A8O17_17530	ENOG4108NHD	germination protein
A8O17_17535	ENOG4105C54	Major Facilitator superfamily
A8O17_17540	ENOG4108KGH	TRANSCRIPTIONal
A8O17_17545	ENOG4105J7I	hydrolase
A8O17_17550	ENOG4105K4H	Nlp p60 protein
A8O17_17560	ENOG4105PNM	synthesis protein
A8O17_17570	ENOG4105N98	Capsule biosynthesis protein capB
A8O17_17575	ENOG4105ETE	Transcriptional regulator (LacI family
A8O17_17580	ENOG4108RVA	ribokinase
A8O17_17585	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
A8O17_17590	ENOG4105C2J	ABC transporter
A8O17_17595	ENOG4105CNN	ABC, transporter
A8O17_17600	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A8O17_17615	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
A8O17_17620	ENOG4107FQX	Alpha-acetolactate decarboxylase
A8O17_17630	ENOG4107RSM	transcriptional regulator
A8O17_17645	ENOG4106UIA	
A8O17_17660	ENOG4107XC4	flavin reductase domain protein, FMN-binding
A8O17_17670	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A8O17_17680	ENOG4105CAH	Chromate
A8O17_17685	ENOG4105FGV	Chromate
A8O17_17695	ENOG4108WS4	fmn reductase
A8O17_17700	ENOG4107V2S	Transcriptional regulator
A8O17_17705	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A8O17_17710	ENOG4106YAD	MORN repeat variant
A8O17_17730	ENOG4108XI2	Domain of unknown function (DUF1963)
A8O17_17735	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A8O17_17740	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
A8O17_17745	ENOG4107YJ4	chain length determinant protein
A8O17_17750	ENOG4105HTX	biosynthesis protein
A8O17_17760	ENOG4105KBK	Zinc finger, swim domain protein
A8O17_17765	ENOG4105C0D	helicase
A8O17_17770	ENOG410667J	hydrolase
A8O17_17775	ENOG4105E98	transcriptional regulator DeoR family
A8O17_17780	ENOG4105Z8H	single-stranded DNA-binding protein
A8O17_17805	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A8O17_17810	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A8O17_17820	ENOG4105CGA	flagellar basal-body rod protein FlgG
A8O17_17830	ENOG4105DFF	Rod shape-determining protein mreb
A8O17_17835	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
A8O17_17840	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
A8O17_17845	ENOG4105CZM	Major Facilitator
A8O17_17850	ENOG4108M26	parallel beta-helix repeat protein
A8O17_17855	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A8O17_17860	ENOG41080V3	Major Facilitator superfamily
A8O17_17865	ENOG4105D3W	isochorismatase
A8O17_17870	ENOG4107P26	
A8O17_17875	ENOG4105BZU	Histidine kinase
A8O17_17885	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
A8O17_17895	ENOG4105FRN	stage II sporulation protein
A8O17_17900	ENOG4107TCE	N-acetyltransferase
A8O17_17920	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A8O17_17925	ENOG4107TXC	Transcriptional regulator
A8O17_17930	ENOG4106BRK	
A8O17_17935	ENOG4108RYK	Nad-dependent epimerase dehydratase
A8O17_17940	ENOG4108Z40	Transcriptional regulator
A8O17_17945	ENOG4105CQM	Urea amidohydrolase subunit alpha
A8O17_17950	ENOG4105KI2	Urea amidohydrolase subunit beta
A8O17_17955	ENOG4108YZ9	Urea amidohydrolase subunit gamma
A8O17_17985	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A8O17_17995	ENOG4108TF4	von Willebrand factor, type A
A8O17_18010	ENOG4105JFG	SpoIID LytB domain protein
A8O17_18015	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A8O17_18025	ENOG4106778	Protein of unknown function (DUF1146)
A8O17_18035	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A8O17_18040	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A8O17_18045	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A8O17_18050	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A8O17_18075	ENOG4107RB6	it plays a direct role in the translocation of protons across the membrane (By similarity)
A8O17_18085	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A8O17_18090	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A8O17_18095	ENOG4108UIC	UPF0340 protein
A8O17_18100	ENOG4108YZG	isomerase
A8O17_18105	ENOG4107WAU	Protein tyrosine phosphatase
A8O17_18110	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
A8O17_18115	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A8O17_18125	ENOG4108ZXQ	stage ii sporulation protein r
A8O17_18140	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A8O17_18145	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A8O17_18150	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A8O17_18160	ENOG4107TT2	Auxin Efflux Carrier
A8O17_18165	ENOG4105C6K	Malic enzyme
A8O17_18170	ENOG4107104	thymidine kinase
A8O17_18175	ENOG41082DI	50s ribosomal protein l31
A8O17_18180	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A8O17_18190	ENOG4105CBT	Fructose-1,6-bisphosphatase
A8O17_18195	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A8O17_18200	ENOG4107XMI	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A8O17_18205	ENOG4105D2N	Aldolase
A8O17_18210	ENOG410812K	response regulator receiver protein
A8O17_18220	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A8O17_18230	ENOG4105C1G	acyl-Coa dehydrogenase
A8O17_18235	ENOG4105DF6	Fe-S oxidoreductase
A8O17_18245	ENOG4105E5J	UV damage endonuclease
A8O17_18255	ENOG4105NAE	bifunctional deaminase-reductase domain protein
A8O17_18260	ENOG4105BZ1	(ABC) transporter
A8O17_18265	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A8O17_18280	ENOG4105R3A	Nitrate reductase
A8O17_18285	ENOG4108IUE	nitrate reductase beta subunit
A8O17_18305	ENOG4107V6Q	Cyclic nucleotide-binding domain
A8O17_18315	ENOG4105C75	arginyL-tRNA synthetase
A8O17_18320	ENOG410684U	Domain of unknown function (DUF1934)
A8O17_18330	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A8O17_18380	ENOG4107JM4	Tetratricopeptide repeat
A8O17_18390	ENOG4108UIN	ybak prolyl-trna synthetase associated region
A8O17_18395	ENOG4105CYW	agmatinase
A8O17_18400	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A8O17_18405	ENOG4105BZ4	penicillin-binding protein
A8O17_18410	ENOG4108XFG	YwhD family
A8O17_18415	ENOG4108Z4T	Peptidase M50
A8O17_18420	ENOG41069HH	4-oxalocrotonate tautomerase
A8O17_18425	ENOG41067TZ	transcriptional regulator, MarR family
A8O17_18430	ENOG4105C22	threonyL-tRNA synthetase
A8O17_18440	ENOG4105C57	major facilitator superfamily
A8O17_18445	ENOG41062ES	Transcriptional regulator
A8O17_18455	ENOG4105DCI	Phosphohydrolase
A8O17_18465	ENOG4108VCI	transcription factor, rsfa family
A8O17_18470	ENOG4108RNG	Permease of the drug metabolite transporter
A8O17_18475	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
A8O17_18480	ENOG4105DUM	transcriptional regulator, lysR family
A8O17_18485	ENOG4108IJ2	phosphate acetyltransferase
A8O17_18500	ENOG4105CHM	Aminotransferase
A8O17_18510	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
A8O17_18515	ENOG4105CHR	reductase
A8O17_18520	ENOG4106CHD	Bacilysin biosynthesis protein bacB
A8O17_18525	ENOG41061WN	bacilysin biosynthesis protein
A8O17_18530	ENOG4105FCW	Major Facilitator superfamily
A8O17_18545	ENOG4105C26	Dehydrogenase
A8O17_18550	ENOG4105D82	Glutamate dehydrogenase
A8O17_18560	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
A8O17_18565	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A8O17_18570	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A8O17_18575	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A8O17_18580	ENOG4107P9E	Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG
A8O17_18585	ENOG4107TY6	Acylneuraminate cytidylyltransferase
A8O17_18595	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
A8O17_18600	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A8O17_18640	ENOG4105C26	Dehydrogenase
A8O17_18645	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A8O17_18650	ENOG4108RJ9	Glycosyl transferase, family 2
A8O17_18670	ENOG4105DWF	phosphomethylpyrimidine kinase
A8O17_18685	ENOG4105C5Y	PTS System
A8O17_18690	ENOG4108QTI	)-transporter
A8O17_18705	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
A8O17_18710	ENOG4105DEN	Luciferase family
A8O17_18715	ENOG4108DBC	nitroreductase
A8O17_18730	ENOG41060D1	Quinol oxidase
A8O17_18735	ENOG4105CCU	oxidase (Subunit III)
A8O17_18740	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A8O17_18745	ENOG4105E2S	oxidase) subunit II
A8O17_18750	ENOG4107BMA	Transglycosylase associated protein
A8O17_18760	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A8O17_18765	ENOG4105WH5	Teichoic acid glycosylation protein
A8O17_18790	ENOG4107ZXU	DSBA oxidoreductase
A8O17_18795	ENOG4105DBE	peroxidase
A8O17_18800	ENOG410650H	(LipO)protein
A8O17_18805	ENOG4107SJW	iron permease, FTR1
A8O17_18810	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A8O17_18820	ENOG4105CMU	LysR family (Transcriptional regulator
A8O17_18825	ENOG4105VAW	lrga family
A8O17_18830	ENOG41067MG	lrgb family
A8O17_18835	ENOG4105D8G	Major Facilitator superfamily
A8O17_18845	ENOG4105DR4	Methyltransferase
A8O17_18855	ENOG4108YV3	Protein of unknown function (DUF2711)
A8O17_18860	ENOG4105CK1	PTS System
A8O17_18865	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
A8O17_18880	ENOG4105X1N	Glycosyl transferase family 8
A8O17_18890	ENOG4105GVJ	transcriptional regulator
A8O17_18895	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A8O17_18900	ENOG4105IIU	Aminopeptidase
A8O17_18910	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A8O17_18925	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
A8O17_18930	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
A8O17_18940	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
A8O17_18945	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
A8O17_18950	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A8O17_18955	ENOG4105F8D	glycoside hydrolase family 4
A8O17_18960	ENOG4105VCP	PTS System
A8O17_18965	ENOG4105CK1	PTS System
A8O17_18970	ENOG4105VZJ	PTS System
A8O17_18975	ENOG4105EMD	TRANSCRIPTIONal
A8O17_18985	ENOG4108VX5	3-methyladenine DNA glycosylase
A8O17_18990	ENOG4105CH6	catalase
A8O17_19005	ENOG4105DA5	(ABC) transporter
A8O17_19010	ENOG41069JR	
A8O17_19030	ENOG4105ETS	cytosine purines uracil thiamine allantoin
A8O17_19035	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A8O17_19040	ENOG4108JJ8	(ABC) transporter
A8O17_19045	ENOG4108JJ9	ABC, transporter
A8O17_19050	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A8O17_19055	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A8O17_19060	ENOG4105D2K	citrate carrier protein
A8O17_19075	ENOG4107BJW	polysaccharide deacetylase
A8O17_19095	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
A8O17_19105	ENOG4105CMR	udp-glucose 4-epimerase
A8O17_19110	ENOG4105KIS	phospholipid-binding protein
A8O17_19115	ENOG4108WAV	Transcriptional regulator
A8O17_19125	ENOG4105BZU	Histidine kinase
A8O17_19130	ENOG4105WH1	Two component transcriptional regulator luxr family
A8O17_19135	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A8O17_19165	ENOG4105DTD	Dehydrogenase
A8O17_19170	ENOG4108IIH	CoA-transferase subunit B
A8O17_19175	ENOG4105D6N	CoA-transferase, subunit a
A8O17_19180	ENOG4105CY2	Citrate transporter
A8O17_19190	ENOG4105DHI	Methyltransferase
A8O17_19215	ENOG4105CH6	catalase
A8O17_19220	ENOG4105D4T	Citrate transporter
A8O17_19225	ENOG4108RZ2	Glycoside hydrolase family 16
A8O17_19230	ENOG4105CID	antiterminator
A8O17_19240	ENOG4105DEU	major facilitator superfamily
A8O17_19245	ENOG4105C1J	atp-dependent rna helicase
A8O17_19250	ENOG4107TDE	lipolytic protein G-D-S-L family
A8O17_19305	ENOG4105CNA	YD repeat protein
A8O17_19315	ENOG4107YZX	Universal stress protein
A8O17_19320	ENOG4105CS2	ec 3.2.1.21
A8O17_19325	ENOG4105C5Y	PTS System
A8O17_19340	ENOG4107EV6	Inherit from COG: YD repeat protein
A8O17_19355	ENOG4106Z5D	Glycoside Hydrolase Family 43
A8O17_19370	ENOG4105C84	Histidine ammonia-lyase
A8O17_19375	ENOG4105CGP	Urocanate hydratase
A8O17_19380	ENOG4105CI2	imidazolone-5-propionate hydrolase
A8O17_19385	ENOG4107W25	arginase agmatinase formiminoglutamase
A8O17_19395	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A8O17_19400	ENOG4105D9N	nucleoside
A8O17_19410	ENOG4107RHR	regulatoR
A8O17_19415	ENOG4108TM9	integral membrane protein
A8O17_19420	ENOG4105ENY	Ethanolamine utilization protein eutH
A8O17_19425	ENOG4108PGP	mmge prpd family protein
A8O17_19430	ENOG4105CH2	amidohydrolase
A8O17_19440	ENOG4108HW4	amino acid AbC transporter
A8O17_19445	ENOG4105EAB	amino acid AbC transporter
A8O17_19450	ENOG4108XSB	acetyltransferase, (GNAT) family
A8O17_19455	ENOG4105CPU	Monooxygenase
A8O17_19465	ENOG4107QHE	Choloylglycine hydrolase
A8O17_19470	ENOG410667J	hydrolase
A8O17_19500	ENOG4108V5C	ABC transporter
A8O17_19530	ENOG4105D2N	Aldolase
A8O17_19535	ENOG4107TRN	Xylose isomerase domain protein TIM barrel
A8O17_19540	ENOG4105F0H	myo-inositol catabolism protein
A8O17_19545	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A8O17_19555	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
A8O17_19560	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
A8O17_19565	ENOG4105D7K	pfkb domain protein
A8O17_19570	ENOG4105DH8	myo-inositol catabolism
A8O17_19575	ENOG4105C26	Dehydrogenase
A8O17_19585	ENOG4105CPC	Aldo Keto reductase
A8O17_19600	ENOG4107QNK	)-transporter
A8O17_19605	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A8O17_19615	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A8O17_19620	ENOG4105ST3	Transcriptional regulator
A8O17_19625	ENOG4105C26	Dehydrogenase
A8O17_19630	ENOG4108YM7	Gcn5-related n-acetyltransferase
A8O17_19635	ENOG4105N1N	Cupin superfamily protein
A8O17_19640	ENOG4107Y1Y	Methyltransferase
A8O17_19655	ENOG4105CAQ	asparagine synthetase
A8O17_19660	ENOG4105F22	Major Facilitator Superfamily
A8O17_19665	ENOG4108ITS	PQQ enzyme repeat
A8O17_19675	ENOG41085PJ	rdd domain containing protein
A8O17_19690	ENOG4105J7D	transcriptional regulator
A8O17_19695	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
A8O17_19700	ENOG41061AU	MarR family Transcriptional regulator
A8O17_19710	ENOG41067MG	lrgb family
A8O17_19720	ENOG4105BZW	Glycerate kinase
A8O17_19725	ENOG4105G3Z	GntR family transcriptional regulator
A8O17_19730	ENOG4105CMG	Carbohydrate kinase
A8O17_19735	ENOG4105C6Z	Gluconate
A8O17_19740	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A8O17_19745	ENOG4105D3R	alkyl hydroperoxide reductase
A8O17_19750	ENOG4108JU3	Alkyl hydroperoxide reductase
A8O17_19755	ENOG4105CS2	ec 3.2.1.21
A8O17_19765	ENOG4108S3Y	transcriptional regulator
A8O17_19775	ENOG4106KKU	
A8O17_19780	ENOG4108Z15	abc transporter atp-binding protein
A8O17_19790	ENOG4105Y2Z	radical SAM domain protein
A8O17_19800	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
A8O17_19815	ENOG41069I7	
A8O17_19820	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A8O17_19835	ENOG4105E2A	Dehydrogenase
A8O17_19855	ENOG4105NUN	Orthopoxvirus protein of unknown function (DUF830)
A8O17_19860	ENOG4105WQG	acetyltransferase
A8O17_19865	ENOG410780I	phosphoprotein phosphatase activity
A8O17_19875	ENOG41066UZ	arginase EC 3.5.3.1
A8O17_19880	ENOG4108IQI	permease
A8O17_19885	ENOG4105C8Y	Acetylornithine aminotransferase
A8O17_19890	ENOG4108JUB	Transcriptional regulator
A8O17_19895	ENOG4105BZU	Histidine kinase
A8O17_19905	ENOG4105C0H	protease
A8O17_19910	ENOG4105Q2H	domain protein
A8O17_19925	ENOG4105BZU	Histidine kinase
A8O17_19930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A8O17_19955	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A8O17_19960	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
A8O17_19965	ENOG4105CDU	Replicative dna helicase
A8O17_19990	ENOG4105DJ2	Major Facilitator Superfamily
A8O17_19995	ENOG4105EDW	glycosyl transferase, family 39
A8O17_20000	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A8O17_20005	ENOG4105BZR	domain protein
A8O17_20010	ENOG4108XMW	Membrane
A8O17_20025	ENOG4105KVH	Transcriptional regulator
A8O17_20030	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
A8O17_20055	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
A8O17_20065	ENOG41060CM	Protein of unknown function (DUF2712)
A8O17_20070	ENOG4106NWU	
A8O17_20075	ENOG41064J9	
A8O17_20080	ENOG41064SH	Protein of unknown function (DUF2705)
A8O17_20085	ENOG4108RDQ	ABC transporter
A8O17_20095	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
A8O17_20100	ENOG4105DDN	Pentapeptide repeat-containing protein
A8O17_20105	ENOG4105D94	Major Facilitator Superfamily
A8O17_20110	ENOG4107RSM	transcriptional regulator
A8O17_20115	ENOG41082BV	acetyltransferase
A8O17_20120	ENOG41081I9	integral membrane protein
A8O17_20130	ENOG4108U05	Transcriptional regulator
A8O17_20135	ENOG41082BV	acetyltransferase
A8O17_20145	ENOG4108U7W	acetyltransferase
A8O17_20150	ENOG4105UNS	Pfam:DUF419
A8O17_20155	ENOG4105NAE	bifunctional deaminase-reductase domain protein
A8O17_20160	ENOG4108J8C	transporter major facilitator family protein
A8O17_20175	ENOG4108IPJ	Membrane
A8O17_20180	ENOG4105C7Z	Conserved Protein
A8O17_20185	ENOG4107FCW	Abortive infection protein
A8O17_20195	ENOG4108UW5	maltose o-acetyltransferase
A8O17_20200	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
A8O17_20210	ENOG4105CGK	Exodeoxyribonuclease III
A8O17_20215	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A8O17_20220	ENOG4108UUM	single-stranded DNA-binding protein
A8O17_20225	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A8O17_20230	ENOG4105C3G	gtp-binding protein
A8O17_20235	ENOG4108J2R	molybdopterin oxidoreductase
A8O17_20240	ENOG4105VDK	protein, conserved in bacteria
A8O17_20250	ENOG4108ZDA	Sporulation protein YyaC
A8O17_20255	ENOG4105FA0	parb-like partition protein
A8O17_20260	ENOG4107QJE	Chromosome Partitioning Protein
A8O17_20275	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A8O17_20280	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A8O17_20285	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A8O17_20300	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)