locus-tag	class	description
I653_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
I653_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
I653_00015	ENOG410848D	S4 domain protein YaaA
I653_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
I653_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
I653_00045	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
I653_00055	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
I653_00060	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
I653_00065	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
I653_00070	ENOG4105ZMH	deoxynucleoside kinase
I653_00080	ENOG4105VRS	hydrolase family 18
I653_00085	ENOG4105GTG	Isochorismatase
I653_00090	ENOG4108Z6B	deaminase
I653_00095	ENOG4105C6E	dna polymerase iii
I653_00100	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
I653_00105	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
I653_00115	ENOG41067KS	pro-sigma K processing
I653_00130	ENOG4105CDW	Resistance protein
I653_00135	ENOG4105CXN	decarboxylase
I653_00140	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
I653_00145	ENOG4105X0R	protein from nitrogen regulatory protein P-II
I653_00150	ENOG4105XVJ	Protein of unknown function (DUF327)
I653_00155	ENOG4105FA2	dna polymerase iii
I653_00160	ENOG4105MA4	psp1 domain protein
I653_00165	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
I653_00170	ENOG41060K3	Methyltransferase
I653_00175	ENOG4105VC4	domain protein
I653_00180	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
I653_00185	ENOG4105KRN	Transcriptional regulator, abrb family
I653_00190	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
I653_00195	ENOG4105F8V	Hydrolase, tatD family
I653_00200	ENOG41069ER	domain protein
I653_00210	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
I653_00215	ENOG4105XFA	sporulation peptidase YabG
I653_00220	ENOG4105W42	Veg protein
I653_00225	ENOG4105XEW	small acid-soluble spore protein
I653_00230	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
I653_00235	ENOG4105DFT	pur operon repressor
I653_00240	ENOG4105KME	endoribonuclease L-psp
I653_00245	ENOG4105K4W	Could be involved in septation (By similarity)
I653_00250	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
I653_00255	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
I653_00260	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
I653_00265	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
I653_00275	ENOG4108JA2	transcriptioN-repair coupling factor
I653_00280	ENOG4108M14	stage v sporulation protein t
I653_00290	ENOG4108IY2	MazG family
I653_00295	ENOG41082I2	s4 domain protein
I653_00300	ENOG4105VYY	sporulation protein yabp
I653_00315	ENOG41060GV	RNA binding s1 domain protein
I653_00335	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
I653_00340	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
I653_00345	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
I653_00355	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
I653_00360	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
I653_00365	ENOG4105C6T	cysteine synthase
I653_00370	ENOG4105CRQ	synthase (Component I)
I653_00375	ENOG4105DDQ	anthranilate synthase
I653_00380	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
I653_00385	ENOG4105EEI	dihydropteroate synthase
I653_00390	ENOG4105KRF	dihydroneopterin aldolase
I653_00395	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I653_00405	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
I653_00410	ENOG4105CRK	lysyL-tRNA synthetase
I653_00420	ENOG4108Z0C	Uvrb UvrC protein
I653_00425	ENOG41066A3	ATP guanido phosphotransferase
I653_00435	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
I653_00440	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
I653_00445	ENOG4105CTP	PilT protein domain protein
I653_00450	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
I653_00455	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
I653_00460	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
I653_00470	ENOG4105D7W	serine acetyltransferase
I653_00475	ENOG4105C8N	cysteinyl-tRNA synthetase
I653_00480	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
I653_00485	ENOG4105C2N	RNA methyltransferase TrmH family group 3
I653_00490	ENOG4105M0M	Tetracycline resistance protein
I653_00510	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
I653_00515	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
I653_00525	ENOG4108VZM	50s ribosomal protein L10
I653_00530	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
I653_00535	ENOG4107Y49	methyltransferase
I653_00540	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I653_00545	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I653_00550	ENOG4105XPM	ribosomal protein
I653_00555	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
I653_00560	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
I653_00565	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
I653_00570	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
I653_00575	ENOG4107SKW	Inherit from COG: Alpha beta hydrolase
I653_00580	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
I653_00585	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
I653_00590	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
I653_00595	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
I653_00600	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
I653_00605	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
I653_00610	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
I653_00615	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
I653_00620	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
I653_00625	ENOG41082SA	50s ribosomal protein l29
I653_00630	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
I653_00635	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
I653_00645	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
I653_00655	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
I653_00660	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
I653_00665	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
I653_00670	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
I653_00675	ENOG4105VPB	50S ribosomal protein L30
I653_00680	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
I653_00685	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
I653_00695	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
I653_00705	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
I653_00715	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
I653_00720	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
I653_00725	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I653_00730	ENOG4108ZT0	50S ribosomal protein l17
I653_00735	ENOG4108JJB	ABC transporter
I653_00740	ENOG4108JJB	ABC transporter
I653_00745	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
I653_00750	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
I653_00755	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
I653_00760	ENOG4108UJD	30S ribosomal protein S9
I653_00765	ENOG4108I0C	methyltransferase
I653_00780	ENOG4105D1F	ATP-binding protein
I653_00795	ENOG4108NMV	polysaccharide deacetylase
I653_00800	ENOG4105CHH	sulfate transporter
I653_00810	ENOG4108SA1	esterase
I653_00830	ENOG410874W	AraC family transcriptional regulator
I653_00835	ENOG4105EHZ	conserved protein UCP016719
I653_00840	ENOG4105D17	glycoside hydrolase, family 3 domain protein
I653_00860	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
I653_00870	ENOG4105EWC	Purine nucleoside phosphorylase
I653_00880	ENOG4105EMN	RNA polymerase sigma factor
I653_00890	ENOG4105C8B	TIGR00159 family
I653_00895	ENOG4107U5W	ybbr family
I653_00900	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
I653_00910	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
I653_00920	ENOG4108TWJ	NADH dehydrogenase subunit 5
I653_00940	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
I653_00945	ENOG4105WAB	arsR family transcriptional regulator
I653_00950	ENOG4108RWP	Major Facilitator Superfamily protein
I653_00985	ENOG4105G0J	serine threonine protein kinase
I653_00995	ENOG4106K80	
I653_01005	ENOG4106DDH	Sporulation-specific SASP protein
I653_01015	ENOG4108HWY	Beta-lactamase
I653_01020	ENOG4107E6A	Cytochrome p-450
I653_01030	ENOG4107QTZ	amino acid
I653_01035	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
I653_01040	ENOG4105CXY	transporter
I653_01050	ENOG410645S	MarR family Transcriptional regulator
I653_01055	ENOG4105DCM	major facilitator superfamily
I653_01065	ENOG410631K	Membrane
I653_01070	ENOG4106AXJ	AraC family transcriptional regulator
I653_01075	ENOG41065RQ	ADP-ribosylation crystallin J1
I653_01080	ENOG4106BHF	
I653_01085	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
I653_01090	ENOG4108TCS	Glutamyl endopeptidase
I653_01100	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
I653_01105	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
I653_01110	ENOG4107ZTW	SNARE associated Golgi
I653_01130	ENOG4105C72	UPF0176 protein
I653_01140	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
I653_01145	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
I653_01150	ENOG4108X79	transcriptional regulator
I653_01160	ENOG4105CM2	brancheD-chain amino acid aminotransferase
I653_01165	ENOG4108IQI	permease
I653_01170	ENOG4108J5H	Homocysteine s-methyltransferase
I653_01185	ENOG4105CSV	Glutaminase
I653_01200	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
I653_01205	ENOG4105C26	Dehydrogenase
I653_01210	ENOG4105DJB	Major Facilitator Superfamily
I653_01215	ENOG4105EQX	glucarate dehydratase
I653_01220	ENOG41073TP	transcriptional regulator
I653_01225	ENOG4105CTX	dehydratase
I653_01240	ENOG4106UX7	integral membrane protein
I653_01245	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
I653_01280	ENOG4105MUA	Resistance protein
I653_01290	ENOG4105DGI	Alkaline phosphatase
I653_01295	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
I653_01300	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
I653_01305	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
I653_01310	ENOG4107EPV	Aminotransferase class V
I653_01315	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
I653_01320	ENOG4105J7D	transcriptional regulator
I653_01325	ENOG4107RB3	L-asparaginase
I653_01330	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
I653_01340	ENOG41060AI	SEC-C motif
I653_01350	ENOG4107Y7X	LytTR
I653_01355	ENOG4108IUW	ABC transporter
I653_01360	ENOG4108SDH	ABC, transporter
I653_01365	ENOG4107SET	aldo keto reductase
I653_01395	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
I653_01405	ENOG4105DSE	periplasmic solute binding protein
I653_01410	ENOG4105DIK	(ABC) transporter
I653_01420	ENOG4105DEN	Luciferase family
I653_01425	ENOG4108N0M	stress protein
I653_01430	ENOG4106FN3	tellurium resistance protein
I653_01435	ENOG4106FN3	tellurium resistance protein
I653_01440	ENOG4107TS3	membrane protein, TerC
I653_01445	ENOG4108TTB	tellurium resistance protein
I653_01455	ENOG41079KZ	Major Facilitator Superfamily
I653_01460	ENOG4107XZQ	multidrug resistance protein
I653_01465	ENOG4108A65	Transcriptional regulator
I653_01470	ENOG4108IJ7	Glycine betaine
I653_01475	ENOG4107SQ8	Glycine betaine
I653_01505	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
I653_01545	ENOG4105EIG	urea carboxylase-associated protein 1
I653_01550	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
I653_01555	ENOG4105I1F	Resistance protein
I653_01560	ENOG4107Z3Y	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
I653_01565	ENOG41089UC	methyltransferase, type 11
I653_01570	ENOG4105C5Q	Transcriptional regulator
I653_01575	ENOG4105I82	acetyl xylan esterase
I653_01580	ENOG410756H	nucleotidyltransferase
I653_01590	ENOG4105C26	Dehydrogenase
I653_01595	ENOG4105CK7	Sodium proline symporter
I653_01600	ENOG4107YHD	transcriptional regulator
I653_01610	ENOG4108PJD	permease
I653_01615	ENOG4105U6C	Alpha beta hydrolase fold protein
I653_01625	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
I653_01630	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
I653_01635	ENOG4108IFG	nitrite reductase, (NAD(P)H)
I653_01640	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
I653_01660	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
I653_01670	ENOG4105CKI	cobalamin synthesis protein
I653_01675	ENOG4105E5Q	amino acid AbC transporter
I653_01680	ENOG4107XKZ	Amino acid ABC superfamily ATP binding cassette transporter binding protein
I653_01695	ENOG4105HHM	rdd domain containing protein
I653_01705	ENOG4105CS2	ec 3.2.1.21
I653_01720	ENOG4105C8Q	Methyl-accepting chemotaxis
I653_01725	ENOG41080HJ	6-phospho 3-hexuloisomerase
I653_01730	ENOG4108VA3	3-hexulose-6-phosphate synthase
I653_01735	ENOG4105KVH	Transcriptional regulator
I653_01790	ENOG4105SX7	Transporter
I653_01800	ENOG4105W8Z	4'-phosphopantetheinyl transferase
I653_01810	ENOG4105CDA	abc transporter atp-binding protein
I653_01815	ENOG4105DRP	amino acid AbC transporter
I653_01825	ENOG4106P55	Transcriptional regulator
I653_01830	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
I653_01835	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
I653_01840	ENOG41069ZX	
I653_01845	ENOG41069ZX	
I653_01855	ENOG4105DUX	Transporter
I653_01870	ENOG4105E1K	spore germination protein
I653_01890	ENOG4107WD8	ABC transporter, permease
I653_01895	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
I653_01900	ENOG4105BZU	Histidine kinase
I653_01925	ENOG4105CFH	Aspartokinase
I653_01930	ENOG4105DHS	permease protein
I653_01935	ENOG4105CM4	permease protein
I653_01940	ENOG4108IPW	abc transporter atp-binding protein
I653_01955	ENOG4105R8C	Transcriptional regulator
I653_01960	ENOG4108DBC	nitroreductase
I653_01965	ENOG41067V3	Antibiotic biosynthesis monooxygenase
I653_01970	ENOG4105YVS	arsR family transcriptional regulator
I653_01980	ENOG4108JPW	Aminotransferase
I653_01985	ENOG4105C26	Dehydrogenase
I653_02000	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
I653_02005	ENOG4105KTB	nuclear export factor GLE1
I653_02010	ENOG4108T5E	Copper resistance protein
I653_02015	ENOG4108ZYE	Transcriptional regulator
I653_02040	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
I653_02045	ENOG4108ZX0	Signal peptidase I
I653_02070	ENOG4105E7W	lamb ycsf family protein
I653_02075	ENOG4105C5A	transporter
I653_02080	ENOG4105CFM	UPF0317 protein
I653_02085	ENOG4105P4J	Allophanate hydrolase, subunit 1
I653_02095	ENOG4107258	Transcriptional regulator
I653_02100	ENOG4105XJB	lipolytic protein G-D-S-L family
I653_02110	ENOG41061CK	Antibiotic biosynthesis monooxygenase
I653_02115	ENOG4107RVG	penicillin-binding protein
I653_02120	ENOG4107QM2	Aldo Keto reductase
I653_02125	ENOG4105ETD	TRANSCRIPTIONal
I653_02135	ENOG4105HMZ	Methyltransferase
I653_02140	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
I653_02155	ENOG410606W	general stress protein
I653_02165	ENOG4105VCH	membrane
I653_02175	ENOG4105C9U	ATP-dependent DNA helicase RecQ
I653_02190	ENOG4105I5R	Uncharacterized protein conserved in bacteria (DUF2334)
I653_02195	ENOG4107R8N	Glycosyl transferase, family 2
I653_02205	ENOG4105C0X	amino acid
I653_02225	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
I653_02235	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
I653_02240	ENOG4105EU9	
I653_02245	ENOG4105QVS	general stress protein
I653_02250	ENOG41082W1	Cupin 2, conserved barrel domain protein
I653_02265	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
I653_02270	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
I653_02275	ENOG4108MRH	transcriptional regulatory protein
I653_02280	ENOG4107QJT	sodium dicarboxylate symporter
I653_02285	ENOG4106F5Q	Membrane
I653_02295	ENOG4105CJ1	ABC, transporter
I653_02310	ENOG4105FDT	acyl-CoA dehydrogenase
I653_02330	ENOG4105SZ6	Thioredoxin
I653_02335	ENOG4105CPF	Cell wall formation (By similarity)
I653_02340	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
I653_02345	ENOG4105C1J	atp-dependent rna helicase
I653_02350	ENOG410905X	membrane-flanked domain protein
I653_02355	ENOG4105CKV	Membrane
I653_02365	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
I653_02370	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
I653_02375	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
I653_02385	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
I653_02390	ENOG4107MMM	Anti-sigma-factor antagonist
I653_02395	ENOG4105FUA	antagonist
I653_02400	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
I653_02405	ENOG4107SGM	protein serine threonine phosphatase
I653_02410	ENOG4105WN5	stage II sporulation protein
I653_02415	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
I653_02425	ENOG41064BQ	Phosphatase
I653_02435	ENOG4105M5P	UPF0310 protein
I653_02440	ENOG4105RV9	Transcriptional regulator
I653_02465	ENOG4105CJA	serine threonine protein kinase
I653_02470	ENOG4105CJA	serine threonine protein kinase
I653_02475	ENOG4105BZ1	(ABC) transporter
I653_02495	ENOG4105VZ8	Transcriptional regulator
I653_02505	ENOG4105ECK	Fatty Acid Desaturase
I653_02510	ENOG4105VEQ	Cold shock protein
I653_02515	ENOG4108VJ1	Transcriptional regulator (CarD family
I653_02520	ENOG4108MCI	Transcriptional regulator, ARAC family
I653_02525	ENOG4108UZ3	Transporter
I653_02530	ENOG41086D8	Transcriptional regulator
I653_02535	ENOG4107U9B	transcriptional regulator
I653_02540	ENOG4105DXI	Major Facilitator superfamily
I653_02550	ENOG4105CZ9	Domain of unknown function (DU1801)
I653_02555	ENOG4105GIG	
I653_02560	ENOG4105T38	integral membrane protein
I653_02565	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
I653_02570	ENOG4108ZMQ	domain protein
I653_02575	ENOG4105MJ9	esterase
I653_02580	ENOG4107Z6X	Transcriptional regulator
I653_02590	ENOG4105KVH	Transcriptional regulator
I653_02595	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
I653_02600	ENOG4105EQ0	Major Facilitator superfamily
I653_02605	ENOG4108JGH	Tetr family transcriptional regulator
I653_02615	ENOG41082YX	Transcriptional regulator, arsr family
I653_02620	ENOG4107R5R	arsenical pump membrane protein
I653_02630	ENOG4105Z7P	Acetyltransferase (GNAT) family
I653_02635	ENOG4108KGH	TRANSCRIPTIONal
I653_02640	ENOG4108ZJ4	polysaccharide deacetylase
I653_02650	ENOG4105US7	Histidine kinase
I653_02655	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
I653_02660	ENOG4107Y9U	Membrane
I653_02670	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
I653_02675	ENOG4108ZHR	arsR family transcriptional regulator
I653_02680	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
I653_02695	ENOG4105ENE	Histidine kinase
I653_02700	ENOG4108VB1	regulatoR
I653_02705	ENOG4105EYF	MMPL domain protein
I653_02710	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
I653_02715	ENOG4108UQV	Membrane
I653_02720	ENOG4108Z5V	transcriptional regulator, merr family
I653_02725	ENOG41076HS	cation diffusion facilitator family transporter
I653_02730	ENOG4108TVJ	Nitroreductase
I653_02735	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
I653_02740	ENOG4108VGI	doxx family
I653_02745	ENOG4105XXY	Thioredoxin
I653_02765	ENOG410900G	Protein of unknown function (DUF421)
I653_02770	ENOG4108QY0	Membrane
I653_02790	ENOG4105PF9	Transcriptional regulator
I653_02800	ENOG4105WQG	acetyltransferase
I653_02810	ENOG4105F27	Major Facilitator
I653_02825	ENOG4105C85	amino acid
I653_02835	ENOG41062A4	Transcriptional regulator
I653_02840	ENOG4105EYF	MMPL domain protein
I653_02845	ENOG4108TVJ	Nitroreductase
I653_02850	ENOG4105FS7	Transcriptional regulator
I653_02855	ENOG4105C2C	drug resistance transporter, Bcr CflA
I653_02865	ENOG4105DRR	Transcriptional regulator, GntR family
I653_02870	ENOG4105VRS	hydrolase family 18
I653_02885	ENOG4105G6Z	alkaline phosphatase
I653_02890	ENOG4108ZMX	Domain of unknown function (DU1801)
I653_02900	ENOG4108YM7	Gcn5-related n-acetyltransferase
I653_02905	ENOG4107TVP	HD domain protein
I653_02910	ENOG41090UD	(LipO)protein
I653_02915	ENOG4105F27	Major Facilitator
I653_02920	ENOG4105VZJ	PTS System
I653_02925	ENOG4105VCP	PTS System
I653_02930	ENOG4105CK1	PTS System
I653_02935	ENOG4105CS2	ec 3.2.1.21
I653_02940	ENOG4108TZY	GntR Family Transcriptional Regulator
I653_02945	ENOG4105EVU	fructokinase
I653_02950	ENOG4105DG6	mannose-6-phosphate isomerase
I653_02955	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
I653_02970	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
I653_02975	ENOG4105K8N	protein family UPF0079, ATPase
I653_02980	ENOG41072GX	Peptidase M22 Glycoprotease
I653_02985	ENOG410801F	ribosomal-protein-alanine acetyltransferase
I653_02990	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
I653_02995	ENOG4105C5H	ABC transporter
I653_03000	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
I653_03005	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
I653_03010	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
I653_03015	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
I653_03025	ENOG4108TYN	CAAX amino terminal protease family protein
I653_03030	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
I653_03035	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
I653_03045	ENOG4105PGZ	NB-ARC domain
I653_03050	ENOG4105CPQ	Dehydrogenase
I653_03055	ENOG4105CT4	transporter
I653_03065	ENOG41087YS	Phage shock protein A
I653_03070	ENOG4105DQX	Zinc finger domain
I653_03075	ENOG4108WV1	Pfam:DUF477
I653_03085	ENOG4108ZMR	Ion transport 2 domain-containing protein
I653_03090	ENOG4107QNK	)-transporter
I653_03120	ENOG4107YUH	hydrolase
I653_03130	ENOG4107STQ	Multicopper oxidase
I653_03135	ENOG4105C85	amino acid
I653_03145	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
I653_03175	ENOG4105C7N	Xanthine uracil vitamin C permease
I653_03200	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
I653_03205	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
I653_03210	ENOG4105C83	adenylosuccinate lyase
I653_03215	ENOG4105C8V	SAICAR synthetase
I653_03220	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
I653_03225	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
I653_03230	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
I653_03240	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
I653_03245	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
I653_03250	ENOG4105DC1	bifunctional purine biosynthesis protein purh
I653_03255	ENOG4105C12	Phosphoribosylglycinamide synthetase
I653_03265	ENOG4105DVH	amino acid
I653_03280	ENOG4108R5T	secreted protein
I653_03285	ENOG4105KGF	protein, YerC YecD
I653_03290	ENOG4105CBC	glutamate synthase
I653_03295	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
I653_03300	ENOG4105C4R	Atp-dependent dna helicase
I653_03305	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
I653_03315	ENOG4105CRN	Aminoglycoside phosphotransferase
I653_03320	ENOG4105KT7	mgtC SapB transporter
I653_03325	ENOG4105CK7	Sodium proline symporter
I653_03330	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
I653_03335	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
I653_03340	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
I653_03345	ENOG4108IG5	Transcriptional regulator
I653_03355	ENOG4105CBD	Diacylglycerol kinase
I653_03360	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
I653_03365	ENOG41069I7	
I653_03435	ENOG4108HFV	
I653_03455	ENOG4105CDY	transcriptional regulatory protein
I653_03465	ENOG4105M4P	Tetr family transcriptional regulator
I653_03470	ENOG41062KD	Inherit from COG: ketosteroid isomerase-like protein
I653_03475	ENOG4107S9F	NmrA family
I653_03490	ENOG4105WEF	catalase
I653_03495	ENOG4105M18	-acetyltransferase
I653_03510	ENOG4105C2F	Histidine kinase
I653_03515	ENOG4105EQD	regulatoR
I653_03520	ENOG410769Z	extracellular solute-binding protein family 1
I653_03525	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
I653_03530	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
I653_03535	ENOG4105F5H	Glycosyl Hydrolase Family 88
I653_03540	ENOG41075H3	AraC family transcriptional regulator
I653_03545	ENOG4107TDE	lipolytic protein G-D-S-L family
I653_03560	ENOG4105CX8	fg-gap repeat protein
I653_03565	ENOG4105CX8	fg-gap repeat protein
I653_03570	ENOG4107TDE	lipolytic protein G-D-S-L family
I653_03580	ENOG4105EKC	
I653_03585	ENOG4105E0S	extracellular solute-binding protein family 1
I653_03595	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
I653_03600	ENOG4105F8D	glycoside hydrolase family 4
I653_03605	ENOG4105H67	Protein of unknown function (DUF421)
I653_03610	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
I653_03615	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
I653_03635	ENOG4106I4J	membrane
I653_03640	ENOG41061H0	Monooxygenase
I653_03645	ENOG4108R1P	
I653_03650	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
I653_03655	ENOG4105E0M	Sulfatase
I653_03660	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
I653_03670	ENOG41090R9	glycosyltransferase
I653_03675	ENOG4107R51	Glycosyl transferase, family 2
I653_03680	ENOG41090R9	glycosyltransferase
I653_03685	ENOG4105EU0	Major facilitator Superfamily
I653_03695	ENOG4105CUB	amino acid
I653_03700	ENOG4105C26	Dehydrogenase
I653_03705	ENOG4105FKZ	Methyl-accepting chemotaxis
I653_03710	ENOG4105C5H	ABC transporter
I653_03720	ENOG4107SWG	transcriptional regulator MERR family
I653_03725	ENOG4105DXB	Major Facilitator superfamily
I653_03740	ENOG4105C5H	ABC transporter
I653_03745	ENOG4105FDU	atp-dependent rna helicase
I653_03755	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
I653_03760	ENOG4105E0A	ABC, transporter
I653_03765	ENOG4108U1V	ABC transporter, permease
I653_03770	ENOG4105DQ5	transport system permease protein
I653_03775	ENOG4108HUF	Transporter
I653_03790	ENOG4108J20	pectate lyase
I653_03795	ENOG4107QPK	)-transporter
I653_03805	ENOG4108MRH	transcriptional regulatory protein
I653_03835	ENOG410855V	Acylphosphatase
I653_03840	ENOG4108RPX	mosc domain containing protein
I653_03860	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
I653_03885	ENOG4105GEU	Spore germination protein
I653_03895	ENOG4108Q5U	germination protein, ger(x)c family
I653_03900	ENOG4105E1K	spore germination protein
I653_03905	ENOG4105C5Y	PTS System
I653_03910	ENOG4105CG3	alpha amylase, catalytic region
I653_03915	ENOG4107414	GntR family transcriptional regulator
I653_03920	ENOG4108RCM	Nitroreductase
I653_03925	ENOG4105CGH	5'-nucleotidase
I653_03930	ENOG4107RKG	DJ-1/PfpI family
I653_03945	ENOG4105KJF	protein tyrosine phosphatase
I653_03955	ENOG4107U9T	Pfam:Ribonuclease_BN
I653_03965	ENOG4108ISG	Major Facilitator
I653_03975	ENOG4105UPD	Calcium Proton
I653_03985	ENOG4105D8X	mechanosensitive ion channel
I653_04005	ENOG4106KE4	Dehydrogenase
I653_04010	ENOG4105D7N	magnesium and cobalt transport protein CorA
I653_04020	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
I653_04045	ENOG4107RUY	(E1 component), alpha subunit
I653_04055	ENOG4107QKR	Dehydrogenase
I653_04065	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
I653_04070	ENOG41069DP	small acid-soluble spore protein
I653_04075	ENOG4105KK4	UPF0060 membrane protein
I653_04100	ENOG4105F8D	glycoside hydrolase family 4
I653_04105	ENOG4108Q3X	Transcriptional regulator
I653_04110	ENOG4105CI1	PTS System
I653_04115	ENOG4105BZ1	(ABC) transporter
I653_04120	ENOG4105BZ1	(ABC) transporter
I653_04130	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_04135	ENOG4105BZU	Histidine kinase
I653_04140	ENOG4105WH1	Two component transcriptional regulator luxr family
I653_04145	ENOG4105CJ1	ABC, transporter
I653_04150	ENOG41090VJ	ABC-2 type transporter
I653_04155	ENOG4108KYE	ABC-2 type transporter
I653_04165	ENOG4105U3E	Transcriptional regulator
I653_04170	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
I653_04175	ENOG4105EJ2	Transcriptional regulator
I653_04190	ENOG4105CJ1	ABC, transporter
I653_04195	ENOG4105H93	Acyltransferase family
I653_04200	ENOG4105YA8	Transcriptional regulator
I653_04205	ENOG4107Y80	Major Facilitator superfamily
I653_04210	ENOG4108YYS	metal-dependent hydrolase (By similarity)
I653_04215	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
I653_04220	ENOG410834F	Transcriptional regulator
I653_04230	ENOG4108MES	Periplasmic binding protein
I653_04235	ENOG4105DQ5	transport system permease protein
I653_04240	ENOG4108IHU	transport system permease protein
I653_04245	ENOG4105JAB	phenazine biosynthesis protein, phzf family
I653_04250	ENOG4107Y03	Nitroreductase
I653_04265	ENOG4105ECP	epimerase
I653_04280	ENOG4105F27	Major Facilitator
I653_04300	ENOG4106AKJ	
I653_04305	ENOG4105D74	hydrolase
I653_04310	ENOG4105CKK	Glycosyl transferase, family 2
I653_04315	ENOG4105EJV	Membrane
I653_04320	ENOG41067AE	Membrane-bound metal-dependent hydrolase
I653_04325	ENOG4105CEN	a g-specific adenine glycosylase
I653_04330	ENOG4106BXE	
I653_04335	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
I653_04350	ENOG4105EVI	UPF0374 protein
I653_04355	ENOG4105BZ1	(ABC) transporter
I653_04360	ENOG4107NBY	Membrane
I653_04370	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I653_04375	ENOG4105G5W	regulator Fur family
I653_04395	ENOG4108N23	SpoOM-related protein
I653_04410	ENOG4105EC3	peptidase S51, dipeptidase E
I653_04415	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
I653_04420	ENOG4105DNP	FAD linked oxidase domain protein
I653_04435	ENOG4105E2Y	ABC, transporter
I653_04440	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
I653_04445	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
I653_04450	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
I653_04465	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
I653_04470	ENOG4107D63	
I653_04475	ENOG4105VZ8	Transcriptional regulator
I653_04485	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
I653_04495	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
I653_04520	ENOG4105CYN	Serine protein kinase
I653_04525	ENOG4106AKX	UPF0229 protein
I653_04530	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
I653_04535	ENOG4105CW7	secretion protein, HlyD family
I653_04540	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
I653_04545	ENOG4105CS1	NAD(P)H quinone oxidoreductase
I653_04560	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
I653_04565	ENOG4105CZV	ABC transporter
I653_04570	ENOG4105CJ1	ABC, transporter
I653_04575	ENOG4108TU7	Inherit from COG: (ABC) transporter
I653_04580	ENOG4105VEQ	Cold shock protein
I653_04590	ENOG4105BZU	Histidine kinase
I653_04630	ENOG4108YBP	pseudouridine synthase
I653_04640	ENOG41080XP	Cbs domain
I653_04645	ENOG4107YBY	Hydrolase
I653_04650	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
I653_04655	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
I653_04660	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
I653_04670	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
I653_04675	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
I653_04685	ENOG4105BZU	Histidine kinase
I653_04690	ENOG4105WH1	Two component transcriptional regulator luxr family
I653_04735	ENOG4105ED1	spovr family
I653_04740	ENOG4105G6Z	alkaline phosphatase
I653_04755	ENOG4105BZN	citrate synthase
I653_04760	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
I653_04765	ENOG4105CUB	amino acid
I653_04770	ENOG4105C8J	)-transporter
I653_04775	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
I653_04780	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
I653_04795	ENOG4105J37	
I653_04800	ENOG4108AEY	RNA polymerase sigma factor
I653_04805	ENOG4108FN7	Aldo keto reductase
I653_04810	ENOG4105F6E	Acyl-transferase
I653_04815	ENOG4105C37	(CBS) domain
I653_04825	ENOG4105CHM	Aminotransferase
I653_04830	ENOG4105C37	(CBS) domain
I653_04840	ENOG4105WMR	Protein CrcB homolog
I653_04845	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
I653_04855	ENOG4105D64	Mechanosensitive ion channel
I653_04860	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
I653_04865	ENOG4107VMI	polysaccharide deacetylase
I653_04870	ENOG4105F0I	Aminotransferase
I653_04890	ENOG4105BZ1	(ABC) transporter
I653_04895	ENOG4105BZ1	(ABC) transporter
I653_04915	ENOG410839P	
I653_04925	ENOG4106MP8	UPF0754 membrane protein
I653_04930	ENOG4105WZB	UPF0342 protein
I653_04935	ENOG4105F1N	DNA alkylation repair
I653_04945	ENOG4105D4P	Coproporphyrinogen iii oxidase
I653_04950	ENOG4107S91	Sodium hydrogen exchanger
I653_04955	ENOG4105NCW	Trka-c domain protein
I653_04965	ENOG4105CGU	Enoyl-CoA hydratase
I653_04975	ENOG4108IUX	(ABC) transporter
I653_04980	ENOG4105RHA	ABC transporter, permease
I653_04985	ENOG4107VRP	DNA repair exonuclease
I653_04990	ENOG4106D4I	domain protein
I653_04995	ENOG4105EQI	Metal Dependent Phosphohydrolase
I653_05010	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
I653_05050	ENOG4105NBU	tryptophan transport protein
I653_05055	ENOG4105DXJ	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
I653_05060	ENOG4105K59	histidine triad (HIT) protein
I653_05095	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
I653_05100	ENOG4105BZ4	penicillin-binding protein
I653_05105	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
I653_05110	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
I653_05115	ENOG4105C1Q	protoporphyrinogen oxidase
I653_05125	ENOG4105ECB	domain protein
I653_05135	ENOG41090T1	Membrane
I653_05145	ENOG4105DER	m42 family
I653_05160	ENOG4106AXD	
I653_05165	ENOG4108RQ5	Beta-lactamase domain-containing protein
I653_05170	ENOG4105DF9	Lipoate-protein, ligase
I653_05200	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
I653_05205	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
I653_05210	ENOG4105KD7	acetyltransferase
I653_05215	ENOG4105KD7	acetyltransferase
I653_05225	ENOG4108HUF	Transporter
I653_05230	ENOG4107TB6	phosphoglycerate mutase
I653_05240	ENOG4107F3J	Amp-dependent synthetase and ligase
I653_05245	ENOG4107ZYJ	bioY protein
I653_05250	ENOG4106YBV	Methyl-accepting chemotaxis
I653_05270	ENOG4105XVF	Competence transcription factor
I653_05275	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
I653_05280	ENOG4105X3H	Excalibur domain protein
I653_05285	ENOG4105E1V	na solute symporter
I653_05290	ENOG4106CAD	Protein of unknown function (DUF3311)
I653_05295	ENOG41060YP	
I653_05310	ENOG4107SCK	Monooxygenase
I653_05315	ENOG4108INS	Transcriptional regulator
I653_05330	ENOG4105TRI	Hydrolase
I653_05345	ENOG4108KK1	membrane protein AbrB duplication
I653_05350	ENOG4106K7D	Major facilitator family transporter
I653_05355	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
I653_05360	ENOG4105VWP	Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding
I653_05375	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
I653_05385	ENOG4105EYH	Exonuclease
I653_05440	ENOG4105ERH	Fumarylacetoacetate hydrolase
I653_05450	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
I653_05460	ENOG4105CAQ	asparagine synthetase
I653_05470	ENOG4105UQX	Mate efflux family protein
I653_05475	ENOG4106HBX	Transcriptional Regulator AraC Family
I653_05480	ENOG4105ETE	Transcriptional regulator (LacI family
I653_05490	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
I653_05495	ENOG4105SF0	DinB family
I653_05500	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
I653_05505	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
I653_05510	ENOG4105MYW	Pentapeptide repeat protein
I653_05515	ENOG4107S9D	Alpha beta hydrolase
I653_05520	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
I653_05525	ENOG4107RIQ	Sulfate adenylate transferase
I653_05530	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
I653_05535	ENOG4108N5B	2-phosphosulfolactate phosphatase
I653_05540	ENOG41061P3	phosphosulfolactate synthase
I653_05550	ENOG4105DIA	mandelate racemase muconate lactonizing
I653_05555	ENOG4107RCC	Major Facilitator Superfamily
I653_05560	ENOG4108SZE	gCN5-related N-acetyltransferase
I653_05565	ENOG4105MA6	gCN5-related N-acetyltransferase
I653_05580	ENOG4108VPT	UPF0234 protein
I653_05585	ENOG4105QNR	S1 RNA binding domain protein
I653_05605	ENOG4105K7K	Transcriptional regulator
I653_05615	ENOG410751J	
I653_05620	ENOG4105D4Y	metalloprotease
I653_05625	ENOG4105EPR	degv family
I653_05630	ENOG4107AYK	membrAne
I653_05640	ENOG41073B9	
I653_05650	ENOG4108KP7	hydrolase
I653_05655	ENOG4108MXZ	Esterase
I653_05660	ENOG4105VG1	fes assembly suf system protein
I653_05670	ENOG4105IQ5	FAD linked oxidase domain protein
I653_05680	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
I653_05695	ENOG4105C8Y	Acetylornithine aminotransferase
I653_05700	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
I653_05710	ENOG4105DBV	ornithine carbamoyltransferase
I653_05735	ENOG4107RMD	Basic membrane lipoprotein
I653_05750	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
I653_05755	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
I653_05765	ENOG4105C3U	ABC transporter
I653_05770	ENOG4108JQ7	(ABC) transporter
I653_05790	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
I653_05800	ENOG4105C31	Tryptophanyl-tRNA synthetase
I653_05805	ENOG4108J59	Extracellular solute-binding protein, family 5
I653_05810	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
I653_05815	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
I653_05825	ENOG4108JQ7	(ABC) transporter
I653_05840	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
I653_05845	ENOG4108ZCF	integral membrane protein
I653_05850	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
I653_05860	ENOG4105DPN	Oligoendopeptidase f
I653_05870	ENOG4105T58	Dithiol-disulfide isomerase
I653_05875	ENOG4108Z18	K06886 hemoglobin
I653_05880	ENOG4105E4C	Lytic transglycosylase catalytic
I653_05885	ENOG4105MIX	Adenylate cyclase
I653_05900	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
I653_05905	ENOG4105EMS	pseudouridine synthase
I653_05920	ENOG4105ETU	transcriptional activator (TenA
I653_05925	ENOG4108VEU	Thiamine monophosphate synthase
I653_05940	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
I653_05945	ENOG4105D06	uba thif-type nad fad binding protein
I653_05950	ENOG4105DWF	phosphomethylpyrimidine kinase
I653_05955	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
I653_05960	ENOG4107A88	
I653_06010	ENOG4105ENA	helicase
I653_06025	ENOG4108ZMI	UPF0477 protein
I653_06035	ENOG4105C28	cystathionine
I653_06040	ENOG4105C28	cystathionine
I653_06045	ENOG4105D9U	N-acetyltransferase
I653_06050	ENOG4105JHY	Membrane
I653_06075	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
I653_06125	ENOG4105DM4	PTS System
I653_06130	ENOG4105DG6	mannose-6-phosphate isomerase
I653_06135	ENOG4105G7B	Protein of unknown function (DUF2992)
I653_06140	ENOG4105VMI	-acetyltransferase
I653_06145	ENOG4108Z66	YbaK ebsC protein
I653_06160	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
I653_06170	ENOG4108ZJ4	polysaccharide deacetylase
I653_06175	ENOG4107CUJ	Protein of unknown function (DUF2690)
I653_06200	ENOG4108IEG	Formate dehydrogenase Alpha subunit
I653_06225	ENOG4106A3M	Cytochrome p-450
I653_06230	ENOG41087PP	glycosyltransferase MGT family
I653_06240	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
I653_06245	ENOG4105C4B	ABC transporter, permease
I653_06250	ENOG4108IXI	(ABC) transporter
I653_06260	ENOG4105Q95	Cupin 2, conserved barrel domain protein
I653_06275	ENOG4105D2H	Uronic isomerase
I653_06280	ENOG4105CT4	transporter
I653_06285	ENOG4105DG4	malate L-lactate dehydrogenase
I653_06290	ENOG4105CPQ	Dehydrogenase
I653_06295	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
I653_06300	ENOG4105DMW	Dehydrogenase reductase
I653_06305	ENOG4108I5G	Major Facilitator superfamily
I653_06310	ENOG4107KJX	Transcriptional regulator
I653_06315	ENOG4107QZW	Altronate oxidoreductase
I653_06320	ENOG4105CTX	dehydratase
I653_06325	ENOG4107TSN	permease
I653_06335	ENOG4105JD4	ATPase yjob
I653_06350	ENOG41068K0	YCII-related domain
I653_06355	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
I653_06360	ENOG4105KWG	Pfam:DUF1696
I653_06365	ENOG4105K7W	phage-related replication protein
I653_06370	ENOG4105WEF	catalase
I653_06375	ENOG410635T	phage-like element pbsx protein
I653_06425	ENOG4108TFU	terminase (Small subunit)
I653_06430	ENOG4105IG6	Phage terminase, large subunit
I653_06435	ENOG4108MDF	Phage Portal Protein
I653_06460	ENOG41060SN	
I653_06475	ENOG4105PQS	phage protein
I653_06480	ENOG4105FR7	XkdM protein, phage-like element PBSX
I653_06485	ENOG4105MTC	XkdN-like protein
I653_06495	ENOG4108FKH	Transglycosylase SLT domain
I653_06500	ENOG4108WZM	domain protein
I653_06505	ENOG4105X7F	
I653_06515	ENOG4105MFU	Protein of unknown function (DUF2634)
I653_06520	ENOG41066EA	baseplate J family protein
I653_06525	ENOG410906S	phage-like element pbsx protein xkdt
I653_06560	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
I653_06575	ENOG4105CJ3	phosphate transporter
I653_06580	ENOG4107GRR	phosphate transport regulator
I653_06585	ENOG4107R7I	amino acid
I653_06595	ENOG4105EDW	glycosyl transferase, family 39
I653_06600	ENOG4105CKK	Glycosyl transferase, family 2
I653_06610	ENOG4105C0H	protease
I653_06620	ENOG4108ME1	Peptidase M55 D-aminopeptidase
I653_06625	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
I653_06630	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
I653_06635	ENOG4105C3U	ABC transporter
I653_06645	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
I653_06650	ENOG4105DTQ	mandelate racemase muconate lactonizing
I653_06655	ENOG4107SN7	NLP P60 protein
I653_06660	ENOG4108JQ7	(ABC) transporter
I653_06665	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
I653_06670	ENOG4107TUM	Amidinotransferase
I653_06675	ENOG4108S4H	thioesterase Superfamily protein
I653_06680	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
I653_06700	ENOG4108428	Inherit from COG: -acetyltransferase
I653_06710	ENOG41080TC	multidrug resistance protein
I653_06715	ENOG4105CIY	formyltetrahydrofolate deformylase
I653_06720	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
I653_06735	ENOG4105K56	Transcriptional regulator
I653_06740	ENOG4108ZHJ	Organic hydroperoxide resistance protein
I653_06745	ENOG4107Y2X	deaminase
I653_06755	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
I653_06760	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
I653_06770	ENOG4108W7F	transporter, permease
I653_06775	ENOG4108JJB	ABC transporter
I653_06780	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
I653_06785	ENOG4108X43	YKOF domain protein
I653_06790	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
I653_06795	ENOG41062D9	Histidine kinase
I653_06805	ENOG4106849	propeptide, pepSY amd peptidase M4
I653_06820	ENOG4105CJW	magnesium transporter
I653_06825	ENOG4105V75	Transcriptional regulator
I653_06870	ENOG4105DQE	DNA ligase
I653_06875	ENOG4105FDF	Could be involved in DNA repair (By similarity)
I653_06880	ENOG4105BZU	Histidine kinase
I653_06885	ENOG4107T5V	SNARE associated Golgi
I653_06890	ENOG4107TS3	membrane protein, TerC
I653_06895	ENOG4108WZW	RNA polymerase sigma
I653_06905	ENOG410681C	small acid-soluble spore protein
I653_06915	ENOG4105D0M	Protease HtpX homolog
I653_06935	ENOG4108TGC	Acyltransferase
I653_06940	ENOG4105BZU	Histidine kinase
I653_06945	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
I653_06955	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
I653_06960	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
I653_06965	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
I653_06975	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
I653_06980	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
I653_06985	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
I653_06990	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
I653_07010	ENOG4105BZU	Histidine kinase
I653_07015	ENOG41090MY	MarR family Transcriptional regulator
I653_07020	ENOG4105ER2	Ompa motb domain protein
I653_07025	ENOG4105E14	MotA TolQ exbB proton channel
I653_07040	ENOG4108K88	Membrane
I653_07045	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
I653_07050	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
I653_07055	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
I653_07060	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
I653_07065	ENOG4105FEA	Spore maturation protein
I653_07095	ENOG4105F0V	Cell wall hydrolase
I653_07110	ENOG4105C59	p-type ATPase
I653_07120	ENOG4105DC7	peptidase M24
I653_07135	ENOG4105CID	antiterminator
I653_07145	ENOG4105KRI	phosphocarrier protein (HPr
I653_07150	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
I653_07160	ENOG4105F6S	Spore photoproduct lyase
I653_07170	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
I653_07175	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
I653_07180	ENOG4105K4I	Scp-like extracellular
I653_07190	ENOG4105BZU	Histidine kinase
I653_07195	ENOG4105CHM	Aminotransferase
I653_07205	ENOG4107R88	Chemotaxis protein (CheV)
I653_07210	ENOG4105UIN	
I653_07220	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
I653_07230	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
I653_07235	ENOG4105EPM	Diguanylate phosphodiesterase
I653_07240	ENOG4107IN1	Protein of unknown function (DUF1797)
I653_07245	ENOG4108XRC	Protein of unknown function (DUF458) 
I653_07275	ENOG4105NQC	Flavodoxin
I653_07285	ENOG4105CH2	amidohydrolase
I653_07295	ENOG4105D8X	mechanosensitive ion channel
I653_07300	ENOG4105D3R	alkyl hydroperoxide reductase
I653_07305	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I653_07320	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
I653_07325	ENOG4105D06	uba thif-type nad fad binding protein
I653_07330	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
I653_07335	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
I653_07340	ENOG4108ZAF	Molybdopterin
I653_07345	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
I653_07350	ENOG4105BZ1	(ABC) transporter
I653_07355	ENOG4105BZ1	(ABC) transporter
I653_07365	ENOG4107X8C	Efflux transporter RND family MFP subunit
I653_07370	ENOG4105C19	ABC transporter
I653_07375	ENOG4107RBB	ABC transporter, permease
I653_07380	ENOG4105E98	transcriptional regulator DeoR family
I653_07385	ENOG4105DE4	1-phosphofructokinase
I653_07390	ENOG4105DM4	PTS System
I653_07395	ENOG4105C3F	Signal peptidase i
I653_07405	ENOG4105C5H	ABC transporter
I653_07410	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
I653_07415	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
I653_07440	ENOG4105BZU	Histidine kinase
I653_07450	ENOG4107ZYR	domain protein
I653_07460	ENOG4105CN5	Metallo-Beta-Lactamase
I653_07470	ENOG4108X4Q	Hydrolase
I653_07475	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
I653_07495	ENOG4105CPP	Dehydrogenase, E1 component
I653_07500	ENOG4105C7S	Dehydrogenase
I653_07505	ENOG4107QN2	dihydrolipoyl dehydrogenase
I653_07520	ENOG4105CXN	decarboxylase
I653_07525	ENOG4105WBI	UPF0223 protein
I653_07540	ENOG4105ECY	inositol monophosphatase
I653_07550	ENOG4105JQZ	Methyltransferase
I653_07590	ENOG4105CI3	gtp-binding protein typa
I653_07595	ENOG4105QA2	
I653_07610	ENOG4108IAB	Phoh family
I653_07620	ENOG4105CSV	Glutaminase
I653_07625	ENOG4105ZPI	UPF0358 protein
I653_07630	ENOG4105CNI	cell division protein FtsW
I653_07635	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
I653_07645	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
I653_07655	ENOG4105BZ9	Cytochrome C oxidase, subunit I
I653_07660	ENOG4105CCU	oxidase (Subunit III)
I653_07665	ENOG41064X9	cytochrome C oxidase subunit IV
I653_07680	ENOG41080XQ	Signal transduction protein with cbs domains
I653_07685	ENOG4106UY4	Inherit from COG: Scp-like extracellular
I653_07705	ENOG4105WUC	UPF0298 protein
I653_07710	ENOG4106H78	methyltransferase
I653_07715	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
I653_07720	ENOG4105H20	Sporulation integral membrane protein YlbJ
I653_07725	ENOG4105D78	K07001 NTE family protein
I653_07730	ENOG41063PX	domain protein
I653_07740	ENOG4105CDE	UPF0348 protein
I653_07750	ENOG4105KNH	Nucleic acid-binding protein
I653_07755	ENOG41067VY	50S ribosomal protein L32
I653_07780	ENOG4108V6E	Cell division protein mraZ
I653_07785	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
I653_07795	ENOG4105CJN	penicillin-binding protein
I653_07800	ENOG4105CJN	penicillin-binding protein
I653_07810	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
I653_07820	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
I653_07825	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
I653_07830	ENOG4105CNI	cell division protein FtsW
I653_07835	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
I653_07840	ENOG4105D4A	Cell wall formation (By similarity)
I653_07845	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
I653_07850	ENOG4108R2U	division initiation protein
I653_07860	ENOG4105K67	small basic protein
I653_07865	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
I653_07870	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
I653_07880	ENOG4105FFI	sigma-e processing peptidase spoiiga
I653_07885	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I653_07895	ENOG4105DKW	ABC transporter
I653_07905	ENOG4105WR5	sporulation protein, YlmC YmxH family
I653_07910	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
I653_07915	ENOG4105DFA	alanine racemase domain protein
I653_07920	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
I653_07925	ENOG41067XK	integral membrane protein
I653_07930	ENOG4105DBK	s4 domain protein
I653_07940	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
I653_07950	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
I653_07955	ENOG4105C34	Pseudouridine synthase
I653_07960	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
I653_07970	ENOG4105CXT	aspartate transcarbamylase
I653_07980	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
I653_07985	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
I653_07990	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
I653_07995	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
I653_08000	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
I653_08005	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
I653_08010	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
I653_08020	ENOG4107S4M	Sulfate adenylate transferase
I653_08025	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
I653_08030	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
I653_08035	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
I653_08040	ENOG41087GM	Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein
I653_08045	ENOG4105F23	Fibronectin-binding protein
I653_08055	ENOG4105DSJ	YicC domain protein
I653_08060	ENOG4105KC4	UPF0296 protein
I653_08065	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
I653_08075	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
I653_08080	ENOG4105C25	Primosomal protein n'
I653_08085	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
I653_08090	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
I653_08095	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
I653_08100	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
I653_08105	ENOG4108ZF3	Phosphatase
I653_08110	ENOG4105D9P	serine threonine protein kinase
I653_08115	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
I653_08120	ENOG4105DJV	ribulose-phosphate 3-epimerase
I653_08125	ENOG4105FJ0	thiamine
I653_08135	ENOG4105VB9	50S ribosomal protein l28
I653_08140	ENOG4108ZAA	Alkaline-shock protein
I653_08145	ENOG4105DP4	dak2 domain fusion protein ylov
I653_08155	ENOG4105EJQ	L-serine dehydratase
I653_08160	ENOG4105CB5	ATP-dependent DNA helicase recG
I653_08165	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
I653_08175	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
I653_08180	ENOG4105CHR	reductase
I653_08185	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
I653_08190	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
I653_08195	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
I653_08200	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
I653_08210	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
I653_08220	ENOG4105K5M	30s ribosomal protein S16
I653_08225	ENOG4108BW8	UPF0109 protein
I653_08235	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
I653_08240	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
I653_08245	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
I653_08250	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
I653_08255	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
I653_08265	ENOG4105VM1	flagellar
I653_08270	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
I653_08275	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
I653_08280	ENOG4105C79	DNA protecting protein DprA
I653_08285	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
I653_08290	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
I653_08295	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
I653_08300	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
I653_08305	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
I653_08315	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
I653_08320	ENOG4108ZC9	flagellar basal-body rod protein flgc
I653_08325	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
I653_08330	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
I653_08335	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
I653_08350	ENOG4106YF4	Flagellar biosynthesis chaperone
I653_08360	ENOG410696Y	Flagellar hook-length control protein
I653_08365	ENOG410822I	Flagellar hook capping protein
I653_08370	ENOG4108JQA	flagellar
I653_08375	ENOG41068WV	flagellar FlbD family protein
I653_08385	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
I653_08390	ENOG4105DD5	Flagellar motor switch protein
I653_08395	ENOG4107YTP	response regulator receiver protein
I653_08405	ENOG4105CN7	Flagellar biosynthetic protein FliP
I653_08410	ENOG4105VS8	Flagellar biosynthetic protein fliq
I653_08415	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
I653_08420	ENOG4105D00	flagellar biosynthetic protein flhB
I653_08425	ENOG4105D7B	Flagellar biosynthesis protein flha
I653_08430	ENOG4105FZW	flagellar biosynthesis regulator FlhF
I653_08440	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
I653_08445	ENOG4105CBS	Chea signal transduction histidine kinase
I653_08450	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
I653_08465	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I653_08475	ENOG4105CE9	30S ribosomal protein S2
I653_08480	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
I653_08490	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
I653_08495	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
I653_08500	ENOG4105KNE	Phosphatidate cytidylyltransferase
I653_08510	ENOG4105DZP	Membrane-associated zinc metalloprotease
I653_08515	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
I653_08520	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
I653_08525	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
I653_08530	ENOG4105CHV	Transcription elongation factor NusA
I653_08535	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
I653_08540	ENOG4105VHM	ribosomal protein
I653_08545	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
I653_08550	ENOG4105W7A	Protein of unknown function (DUF503)
I653_08555	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
I653_08560	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
I653_08565	ENOG4105DTN	riboflavin biosynthesis protein ribF
I653_08570	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
I653_08575	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
I653_08585	ENOG4105C1V	Peptidase, M16
I653_08595	ENOG4105E35	Dipicolinate synthase subunit A
I653_08600	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
I653_08605	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
I653_08615	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
I653_08625	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
I653_08635	ENOG4105CNU	cell division protein FtsK
I653_08640	ENOG4105FDP	GntR family transcriptional regulator
I653_08660	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
I653_08665	ENOG4105XZV	Protein of unknown function (DUF3243)
I653_08680	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
I653_08685	ENOG4105CEV	competence damage-inducible protein
I653_08695	ENOG4108A04	Beta-lactamase
I653_08700	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
I653_08705	ENOG4105D48	metallophosphoesterase
I653_08710	ENOG4105MCT	stage V sporulation protein S
I653_08720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
I653_08725	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
I653_08740	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
I653_08745	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
I653_08755	ENOG4105IIP	Membrane
I653_08760	ENOG4105W1N	transcriptional regulator
I653_08765	ENOG4108151	Beta-lactamase domain protein
I653_08775	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
I653_08785	ENOG4107QKG	PfaD family
I653_08790	ENOG41062T2	Acyl carrier protein
I653_08795	ENOG4108MH3	Polyketide beta-ketoacyl acyl carrier protein synthase
I653_08800	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
I653_08805	ENOG4108MGH	Enoyl-CoA hydratase
I653_08810	ENOG4108KQ6	Enoyl-CoA hydratase
I653_08815	ENOG4105C0W	non-ribosomal peptide synthetase
I653_08835	ENOG4105C0W	non-ribosomal peptide synthetase
I653_08845	ENOG4106A3M	Cytochrome p-450
I653_08860	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
I653_08870	ENOG4105K7W	phage-related replication protein
I653_08875	ENOG4108X3M	OsmC Ohr family protein
I653_08880	ENOG410814C	multidrug resistance protein
I653_08900	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
I653_08905	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
I653_08920	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
I653_08925	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
I653_08930	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
I653_08935	ENOG4105U6W	MutT NUDIX family protein
I653_08940	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
I653_08945	ENOG4106F1P	AAA ATPase, central domain protein
I653_08955	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
I653_08960	ENOG4105CXI	aluminum resistance protein
I653_08965	ENOG4105KV4	Transcriptional regulator
I653_08970	ENOG4105C5F	glutamine synthetase
I653_08995	ENOG4106BHF	
I653_09005	ENOG41079P0	
I653_09035	ENOG4107AUC	
I653_09055	ENOG4107NTZ	
I653_09085	ENOG4105CT4	transporter
I653_09090	ENOG4105DSG	hydrolase family 43
I653_09095	ENOG4105E2R	ROK family
I653_09100	ENOG4105C93	Xylose Isomerase
I653_09105	ENOG4105CMG	Carbohydrate kinase
I653_09115	ENOG4107Y9E	nuclease
I653_09120	ENOG4105C54	Major Facilitator superfamily
I653_09125	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
I653_09135	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
I653_09145	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
I653_09210	ENOG4108Q8B	Spore germination protein
I653_09215	ENOG4108NHD	germination protein
I653_09230	ENOG4105FVX	
I653_09240	ENOG4105K7W	phage-related replication protein
I653_09250	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
I653_09255	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
I653_09265	ENOG4108SVB	resolvase
I653_09270	ENOG4105VPS	UPF0291 protein
I653_09275	ENOG4105CV1	Transketolase (EC 2.2.1.1)
I653_09295	ENOG4107QIV	Cytochrome c biogenesis protein
I653_09320	ENOG4107DZX	Small, acid-soluble spore protein P
I653_09330	ENOG4108I0Z	Aconitate hydratase
I653_09335	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I653_09350	ENOG41067CD	Small, acid-soluble spore protein Tlp
I653_09360	ENOG4105MI2	
I653_09365	ENOG4105W8X	HesB YadR YfhF-family protein
I653_09370	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
I653_09380	ENOG4105K4P	CoA-binding domain protein
I653_09385	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
I653_09410	ENOG4107QWR	cellulase (EC 3.2.1.4)
I653_09425	ENOG4108MYR	Secreted protein
I653_09430	ENOG4107SYN	Glycosyl hydrolases family 43
I653_09445	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
I653_09450	ENOG4107T5V	SNARE associated Golgi
I653_09460	ENOG4107QX3	carboxylase
I653_09465	ENOG4105E39	Enoyl-CoA hydratase
I653_09470	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
I653_09475	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
I653_09480	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
I653_09485	ENOG4105CEY	Amp-dependent synthetase and ligase
I653_09490	ENOG4105C1G	acyl-Coa dehydrogenase
I653_09500	ENOG4105F32	YngK protein
I653_09505	ENOG4106U2H	Protein of unknown function (DUF1360)
I653_09515	ENOG4105CEY	Amp-dependent synthetase and ligase
I653_09540	ENOG4105C0W	non-ribosomal peptide synthetase
I653_09545	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
I653_09550	ENOG4108N2V	aldose 1-epimerase
I653_09555	ENOG4107QJQ	Mate efflux family protein
I653_09575	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
I653_09580	ENOG4105SKE	transcriptional Regulator LysR family
I653_09585	ENOG4105CB2	alcohol dehydrogenase
I653_09590	ENOG4105BZ8	glutamate synthase
I653_09595	ENOG4105CBC	glutamate synthase
I653_09600	ENOG4105C5Q	Transcriptional regulator
I653_09605	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
I653_09610	ENOG4105II7	pyrroline-5-carboxylate reductase
I653_09630	ENOG4108UB7	
I653_09635	ENOG41068WN	
I653_09640	ENOG4105IE8	Alpha-ketoglutarate permease
I653_09645	ENOG4107U6E	carbohydrate kinase FGGY
I653_09650	ENOG4108M3J	Dehydrogenase
I653_09660	ENOG4108J2R	molybdopterin oxidoreductase
I653_09685	ENOG4105EC8	Methyl-accepting chemotaxis
I653_09695	ENOG4108YQE	rare lipoprotein a
I653_09700	ENOG4105XPP	Protein of unknown function (DUF1275)
I653_09705	ENOG4108NR7	pectate lyase
I653_09710	ENOG4108RAV	Conserved protein
I653_09720	ENOG4105F0F	Oxalate decarboxylase
I653_09740	ENOG41073R8	VanW family
I653_09750	ENOG4105VMP	Transcriptional regulator
I653_09755	ENOG4105NX3	Membrane
I653_09765	ENOG4108Q5Y	Membrane
I653_09775	ENOG4108V4B	ThiJ pfpI
I653_09780	ENOG4108J4B	Beta-lactamase
I653_09800	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
I653_09805	ENOG4107T94	Endo-14-beta-xylanase
I653_09810	ENOG4108J9Q	DNA ligase
I653_09830	ENOG4106ANW	SMI1_KNR4
I653_09835	ENOG4106BHF	
I653_09850	ENOG4108Z7R	Chaperone CsaA
I653_09855	ENOG4105FTV	AraC Family Transcriptional Regulator
I653_09860	ENOG4108HJF	gCN5-related N-acetyltransferase
I653_09870	ENOG4108W8B	Beta-lactamase domain protein
I653_09880	ENOG4105D29	Helix-turn-helix type 11 domain protein
I653_09890	ENOG4105KTU	Transcriptional regulator, arsr family
I653_09900	ENOG4108SJC	Membrane
I653_09920	ENOG4105ECK	Fatty Acid Desaturase
I653_09925	ENOG4108ZGX	Histidine kinase
I653_09930	ENOG4108S01	response regulator
I653_09935	ENOG41069ER	domain protein
I653_09940	ENOG4105C9U	ATP-dependent DNA helicase RecQ
I653_09950	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
I653_09955	ENOG4105SCY	DNAK suppressor
I653_09995	ENOG4105C26	Dehydrogenase
I653_10000	ENOG4105EWU	Squalene--hopene cyclase
I653_10005	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
I653_10010	ENOG4105C8J	)-transporter
I653_10015	ENOG4105C09	Bile acid
I653_10020	ENOG4105C7S	Dehydrogenase
I653_10030	ENOG4107T89	von Willebrand factor, type A
I653_10035	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
I653_10045	ENOG4105K4H	Nlp p60 protein
I653_10050	ENOG41087PP	glycosyltransferase MGT family
I653_10065	ENOG4107QMU	Mate efflux family protein
I653_10070	ENOG4106SCS	STAS domain
I653_10090	ENOG4105FR1	rard protein
I653_10105	ENOG4105C6Z	Gluconate
I653_10110	ENOG41090U3	tautomerase
I653_10130	ENOG4105FBA	Phospholipase Carboxylesterase
I653_10145	ENOG4105E1V	na solute symporter
I653_10165	ENOG4108VXD	carboxy-peptidase
I653_10170	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
I653_10180	ENOG4106Z5R	
I653_10185	ENOG410841Q	phosphoesterase PA-phosphatase related protein
I653_10215	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
I653_10220	ENOG4108TSC	N-acetyltransferase
I653_10225	ENOG4107S4Y	M20 DapE family protein YgeY
I653_10240	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
I653_10280	ENOG4107T32	3-phytase (EC 3.1.3.8)
I653_10285	ENOG4105C5E	polysaccharide biosynthesis protein
I653_10290	ENOG4105E0X	reductase
I653_10295	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
I653_10315	ENOG4105QZP	Uncharacterized protein conserved in bacteria (DUF2140)
I653_10320	ENOG41090WU	lipolytic protein G-D-S-L family
I653_10325	ENOG4108KF3	Electron transport protein SCO1 SenC
I653_10335	ENOG4105C7B	Threonine dehydratase
I653_10345	ENOG4108UT2	hemolysin iii
I653_10355	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
I653_10360	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
I653_10375	ENOG4107YX5	Pfam:DUF548
I653_10380	ENOG4108Y6J	UPF0403 protein
I653_10385	ENOG4105C01	Dihydroxy-acid dehydratase
I653_10410	ENOG4108V06	Glutathione peroxidase
I653_10415	ENOG4105CVG	Homoserine O-transsuccinylase
I653_10455	ENOG41081VK	Ribonuclease
I653_10485	ENOG410890F	Dynamin family
I653_10495	ENOG41065KQ	synthase
I653_10500	ENOG4105C2W	permease
I653_10505	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
I653_10510	ENOG4105CTD	carboxy-peptidase
I653_10515	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
I653_10520	ENOG4108UHU	Aldolase
I653_10525	ENOG4105D7K	pfkb domain protein
I653_10530	ENOG4108M60	Transcriptional regulator
I653_10540	ENOG4105CHR	reductase
I653_10545	ENOG4105DVT	helicase
I653_10560	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
I653_10570	ENOG4108UKS	UPF0398 protein
I653_10585	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
I653_10590	ENOG4108I5C	dEAD DEAH box helicase
I653_10640	ENOG4105BZ4	penicillin-binding protein
I653_10650	ENOG4105CSM	endonuclease III
I653_10660	ENOG4105C5S	asparaginyl-tRNA synthetase
I653_10665	ENOG4105CHM	Aminotransferase
I653_10675	ENOG4105YAC	
I653_10680	ENOG4105DVT	helicase
I653_10685	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
I653_10690	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
I653_10695	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
I653_10700	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
I653_10705	ENOG4105DJ0	Poly(A) Polymerase
I653_10710	ENOG4105CPK	Glycosyl transferase (Group 1
I653_10715	ENOG4105FJR	Lmbe family
I653_10720	ENOG4108Z5K	methylglyoxal synthase
I653_10725	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
I653_10730	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
I653_10735	ENOG4108JYZ	YitT family
I653_10755	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
I653_10775	ENOG41068YB	TPR repeat-containing protein
I653_10780	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
I653_10790	ENOG4105CIH	Imidazole acetol-phosphate transaminase
I653_10800	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
I653_10805	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
I653_10815	ENOG4108I0Q	anthranilate phosphoribosyltransferase
I653_10820	ENOG4105CRQ	synthase (Component I)
I653_10825	ENOG4105KHN	chorismate mutase
I653_10830	ENOG4105D49	3-dehydroquinate synthase
I653_10835	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
I653_10840	ENOG4105BZU	Histidine kinase
I653_10850	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
I653_10855	ENOG4105EAH	synthase
I653_10860	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
I653_10865	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
I653_10875	ENOG4105EUJ	GTP cyclohydrolase i
I653_10880	ENOG4105K70	DNA-binding protein
I653_10885	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
I653_10900	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
I653_10905	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
I653_10910	ENOG41065D1	
I653_10915	ENOG4105S2F	
I653_10930	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
I653_10935	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
I653_10940	ENOG4105CAT	Cytidine monophosphate kinase
I653_10955	ENOG4105MSI	germination protein ypeb
I653_10965	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
I653_10970	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
I653_10985	ENOG4107RGJ	metallophosphoesterase
I653_11000	ENOG4105I7S	Abortive infection protein
I653_11005	ENOG4105C9U	ATP-dependent DNA helicase RecQ
I653_11010	ENOG4105T7X	
I653_11020	ENOG4108SAX	Membrane
I653_11030	ENOG4108JQ1	Dehydrogenase
I653_11035	ENOG4105FF2	Type I DHQase
I653_11050	ENOG4105BZU	Histidine kinase
I653_11055	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
I653_11060	ENOG4105CRE	cytochrome C
I653_11065	ENOG4107TWT	Cytochrome c biogenesis protein
I653_11075	ENOG4105FE9	pseudouridine synthase
I653_11085	ENOG4108JIC	nucleoside recognition domain protein
I653_11090	ENOG4105DZ1	carboxypeptidase
I653_11100	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
I653_11105	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
I653_11120	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
I653_11125	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
I653_11130	ENOG4108R6K	riboflavin synthase, subunit alpha
I653_11135	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
I653_11145	ENOG4105C3F	Signal peptidase i
I653_11150	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
I653_11160	ENOG4107ZE5	PPIases accelerate the folding of proteins
I653_11165	ENOG4105PTM	secreted protein
I653_11170	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
I653_11180	ENOG4105G6R	Stage v sporulation protein ae
I653_11190	ENOG4105CZ3	stage V sporulation protein ad
I653_11195	ENOG41090VF	Stage v sporulation protein ac
I653_11210	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I653_11215	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
I653_11220	ENOG41082AN	stage II sporulation protein
I653_11225	ENOG4105DZ1	carboxypeptidase
I653_11230	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
I653_11235	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
I653_11240	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
I653_11250	ENOG4105I3K	Ferric uptake regulator, Fur family
I653_11255	ENOG4105MZ9	stage II sporulation protein m
I653_11270	ENOG4105DFD	Na H antiporter
I653_11275	ENOG4108IJ0	Aspartate ammonia-lyase
I653_11280	ENOG4105HDK	L-asparaginase
I653_11285	ENOG4108IMY	Transcriptional regulator
I653_11295	ENOG4108YZ4	nudix hydrolase
I653_11305	ENOG4105CPC	Aldo Keto reductase
I653_11325	ENOG4106HZJ	
I653_11330	ENOG4105RHY	Pfam:UPF0157
I653_11335	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
I653_11340	ENOG4108XET	gCN5-related N-acetyltransferase
I653_11350	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
I653_11365	ENOG4105E5W	Transporter
I653_11375	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_11390	ENOG4108IXY	short-chain dehydrogenase reductase
I653_11395	ENOG41069FQ	Metallo-beta-lactamase superfamily
I653_11400	ENOG4105II7	pyrroline-5-carboxylate reductase
I653_11410	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
I653_11420	ENOG410861F	50S ribosomal protein L33
I653_11425	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
I653_11430	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
I653_11435	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
I653_11440	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
I653_11450	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
I653_11455	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
I653_11460	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
I653_11465	ENOG4108HNZ	carboxyl transferase
I653_11470	ENOG4108ZVT	methylmalonyl-coA epimerase
I653_11480	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
I653_11485	ENOG4108QEG	Membrane
I653_11490	ENOG4105CDA	abc transporter atp-binding protein
I653_11495	ENOG4105E5Q	amino acid AbC transporter
I653_11500	ENOG4108HW3	(ABC) transporter
I653_11505	ENOG4108Y6J	UPF0403 protein
I653_11510	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
I653_11525	ENOG4105C7S	Dehydrogenase
I653_11530	ENOG4105CPP	Dehydrogenase, E1 component
I653_11545	ENOG4105CKM	Branched-chain carboxylic acid kinase
I653_11550	ENOG4107RDP	Dehydrogenase
I653_11560	ENOG4108JUB	Transcriptional regulator
I653_11565	ENOG4106CCJ	Protein of unknown function (DUF2627)
I653_11570	ENOG4105CR4	methylisocitrate lyase
I653_11575	ENOG4105DXD	2-methylcitrate dehydratase
I653_11585	ENOG4105C1G	acyl-Coa dehydrogenase
I653_11590	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
I653_11600	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
I653_11605	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
I653_11620	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
I653_11630	ENOG4107QQR	Sporulation
I653_11635	ENOG4105S1Z	Stage IV sporulation protein B
I653_11640	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
I653_11645	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
I653_11650	ENOG4105DX0	Hemolysin A
I653_11660	ENOG4105CTB	Polyprenyl synthetase
I653_11665	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
I653_11670	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
I653_11675	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
I653_11680	ENOG4105M7K	Involved in the transcription termination process (By similarity)
I653_11685	ENOG4108ZSR	alkaline shock protein
I653_11690	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
I653_11710	ENOG410644B	Stage III sporulation protein af
I653_11720	ENOG4105KQ4	Stage iii sporulation protein ad
I653_11725	ENOG4108CQH	stage III sporulation protein AC
I653_11730	ENOG4105KR5	Stage iii sporulation protein
I653_11735	ENOG4105CD2	stage iii sporulation protein aa
I653_11745	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
I653_11750	ENOG4105DC7	peptidase M24
I653_11755	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
I653_11765	ENOG4105CBJ	Metal-dependent enzyme
I653_11780	ENOG4105KST	dependent repressor
I653_11785	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
I653_11790	ENOG4105WZW	rhodanese family
I653_11795	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I653_11800	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
I653_11805	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
I653_11810	ENOG4105C0D	helicase
I653_11825	ENOG4108IMY	Transcriptional regulator
I653_11835	ENOG4105VFR	signal peptidase
I653_11895	ENOG4105C37	(CBS) domain
I653_11915	ENOG4105C5X	domain protein
I653_11940	ENOG4105E0M	Sulfatase
I653_11955	ENOG4107ZXI	Rhomboid family
I653_11965	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
I653_11970	ENOG4105WDJ	50S ribosomal protein L33
I653_11990	ENOG41068DG	YceG-like family
I653_11995	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
I653_12000	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
I653_12005	ENOG4105E2Z	phosphate ABC transporter (Permease
I653_12010	ENOG4105C8U	phosphate abc transporter
I653_12015	ENOG4105CVA	phosphate
I653_12020	ENOG4107RF6	penicillin-binding protein
I653_12030	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
I653_12035	ENOG4105SXS	Protein of unknown function (DUF456)
I653_12050	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
I653_12055	ENOG41063Y9	
I653_12060	ENOG4108U5J	'-nucleotidase
I653_12065	ENOG4105N80	Ferric uptake regulator, Fur family
I653_12070	ENOG4108JYZ	YitT family
I653_12075	ENOG41069ZM	Protein of unknown function (DUF2624)
I653_12080	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
I653_12095	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
I653_12100	ENOG4105EGD	dinuclear metal center protein, YbgI family
I653_12115	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I653_12120	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
I653_12125	ENOG41082VT	Uncharacterized BCR, YaiI/YqxD family COG1671
I653_12130	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
I653_12140	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
I653_12145	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
I653_12150	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
I653_12160	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
I653_12165	ENOG4105KG3	cytidine deaminase
I653_12170	ENOG4107YR5	Diacylglycerol kinase
I653_12175	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
I653_12180	ENOG4105CTJ	Metal Dependent Phosphohydrolase
I653_12190	ENOG4105C9A	Phoh family
I653_12195	ENOG4105EI1	sporulation protein yqfd
I653_12200	ENOG41068P3	sporulation protein YqfC
I653_12210	ENOG4105DI5	UPF0365 protein
I653_12215	ENOG4105F7J	membrane-bound serine protease
I653_12220	ENOG4105KTH	gatB Yqey
I653_12235	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
I653_12240	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
I653_12245	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
I653_12255	ENOG4105CFG	Acts as a chaperone (By similarity)
I653_12260	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
I653_12265	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
I653_12270	ENOG4105CSA	Coproporphyrinogen iii oxidase
I653_12275	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
I653_12285	ENOG4108ZRV	stage ii sporulation protein p
I653_12290	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
I653_12295	ENOG41082YS	Binds directly to 16S ribosomal RNA
I653_12300	ENOG4105TQK	DNA polymerase iii, delta' subunit
I653_12310	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
I653_12315	ENOG4108UK2	deaminase
I653_12320	ENOG4105KQC	Competence protein
I653_12330	ENOG4108D32	Methyltransferase
I653_12340	ENOG4108WF2	Metal Dependent Phosphohydrolase
I653_12345	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
I653_12350	ENOG410812S	Rna-binding protein
I653_12355	ENOG4105E2X	shikimate dehydrogenase
I653_12360	ENOG4105CQW	ribosome biogenesis GTPase YqeH
I653_12365	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
I653_12385	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
I653_12390	ENOG41080BT	SNARE associated Golgi
I653_12405	ENOG4105WFK	nuclease
I653_12410	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I653_12420	ENOG4107Y5K	Resolvase
I653_12435	ENOG4108SWU	Histidine kinase
I653_12440	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
I653_12445	ENOG4105DHF	Membrane
I653_12455	ENOG4108UYN	gCN5-related N-acetyltransferase
I653_12465	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
I653_12520	ENOG4105KR8	Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
I653_12530	ENOG4107Y5K	Resolvase
I653_12540	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
I653_12545	ENOG41068VA	
I653_12550	ENOG4105RV9	Transcriptional regulator
I653_12555	ENOG41082J7	Rhodanese domain protein
I653_12595	ENOG41090E6	transcriptional regulator MERR family
I653_12610	ENOG4105C37	(CBS) domain
I653_12625	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
I653_12630	ENOG4105H3G	oxidoreductase
I653_12635	ENOG4105PGM	cation diffusion facilitator family transporter
I653_12640	ENOG41090U3	tautomerase
I653_12660	ENOG4105KMT	branched-chain amino acid
I653_12665	ENOG4108UMN	azlc family
I653_12670	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
I653_12675	ENOG41067XF	inhibitor
I653_12680	ENOG41067XF	inhibitor
I653_12700	ENOG41064BW	Protein of unknown function (DUF2568)
I653_12715	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
I653_12720	ENOG4105EA8	2-Nitropropane dioxygenase
I653_12725	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
I653_12735	ENOG4108MEK	Metal-binding protein YodA
I653_12740	ENOG410904A	RNA polymerase
I653_12745	ENOG4105CPC	Aldo Keto reductase
I653_12750	ENOG41083Q9	chitosanase
I653_12755	ENOG4105X5K	response regulator receiver protein
I653_12760	ENOG4108VQT	Alpha beta hydrolase fold protein
I653_12765	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
I653_12770	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
I653_12775	ENOG4105Z0X	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_12785	ENOG4105PGS	Spore coat protein
I653_12790	ENOG4105E2A	Dehydrogenase
I653_12805	ENOG4105VUF	Transcriptional regulator
I653_12815	ENOG4105DQ4	alcohol dehydrogenase
I653_12820	ENOG4108Z0Z	intracellular protease Pfpi family
I653_12825	ENOG4108HKT	sucrose-6-phosphate hydrolase
I653_12830	ENOG4105F3R	pts system mannose fructose sorbose family iid
I653_12835	ENOG4105ETZ	PTS System
I653_12840	ENOG4108IQ3	PTS system
I653_12845	ENOG4105YHU	PTS system
I653_12850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
I653_12855	ENOG4105C85	amino acid
I653_12860	ENOG4105N14	lysine exporter protein LysE YggA
I653_12865	ENOG4108NGU	Transcriptional regulator
I653_12870	ENOG4105JVQ	RNA Polymerase
I653_12875	ENOG4108P49	AntiSigma factor
I653_12880	ENOG4105EXC	Acyl-transferase
I653_12885	ENOG4105WDR	
I653_12890	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
I653_12895	ENOG41082JN	Transcriptional regulator
I653_12915	ENOG4105TMB	Formate nitrite transporter
I653_12920	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
I653_12925	ENOG4108JB9	formate dehydrogenase
I653_12940	ENOG4105C28	cystathionine
I653_12955	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
I653_12970	ENOG4107XRG	penicillin-binding protein
I653_12975	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
I653_12980	ENOG4105DBI	uridine monophosphokinase
I653_12985	ENOG4105CFP	Peptidase U32
I653_12990	ENOG4105XYU	peptidase (U32 family)
I653_12995	ENOG4108VQJ	O-methyltransferase
I653_13000	ENOG4105HHA	aminodeoxychorismate lyase
I653_13005	ENOG4105VPH	UPF0473 protein
I653_13010	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
I653_13015	ENOG4105VBH	UPF0297 protein
I653_13020	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
I653_13025	ENOG4105C02	permease
I653_13030	ENOG4105CDA	abc transporter atp-binding protein
I653_13035	ENOG4105CT1	(ABC) transporter
I653_13040	ENOG4105EAD	ABC transporter
I653_13045	ENOG4105DRP	amino acid AbC transporter
I653_13055	ENOG41060CR	
I653_13065	ENOG4105C7H	Helicase, RecD TraA family
I653_13075	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
I653_13080	ENOG4105C3J	Cysteine desulfurase
I653_13090	ENOG4105D1H	recombination factor protein RarA
I653_13095	ENOG4105CUZ	uba thif-type nad fad binding protein
I653_13105	ENOG4105C9M	aspartyl-trna synthetase
I653_13110	ENOG4105CUT	histidyl-tRNA synthetase
I653_13120	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
I653_13130	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
I653_13135	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
I653_13140	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
I653_13145	ENOG41067VP	Protein of unknown function (DUF1049)
I653_13150	ENOG4105NCW	Trka-c domain protein
I653_13155	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
I653_13165	ENOG4105CKP	Polysaccharide Biosynthesis Protein
I653_13170	ENOG4108QG2	Membrane
I653_13175	ENOG4105NAP	
I653_13180	ENOG4105VIE	preprotein translocase, subunit YajC
I653_13185	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
I653_13190	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
I653_13195	ENOG41061AI	Protein of unknown function (DUF2905)
I653_13200	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
I653_13205	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
I653_13215	ENOG4105IE8	Alpha-ketoglutarate permease
I653_13220	ENOG4105CK5	oxidoreductase
I653_13245	ENOG4105BZG	amino acid carrier protein
I653_13250	ENOG4105CDY	transcriptional regulatory protein
I653_13260	ENOG4106678	morphogenetic protein associated with SpoVID
I653_13265	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
I653_13270	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
I653_13275	ENOG4108IYU	L-aspartate oxidase
I653_13290	ENOG4105CQC	Prephenate dehydratase
I653_13295	ENOG41090I5	UPF0735 ACT domain-containing protein
I653_13300	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
I653_13315	ENOG4105K46	50S ribosomal protein l27
I653_13320	ENOG4105X36	(ribosomal) protein
I653_13325	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
I653_13340	ENOG4107QMS	site-determining protein
I653_13345	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
I653_13350	ENOG4105YHC	Rod shape-determining protein MreD
I653_13355	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
I653_13360	ENOG4105DFF	Rod shape-determining protein mreb
I653_13365	ENOG4105W5Q	DNA repair protein (RadC
I653_13370	ENOG4108Z03	MAF-like protein
I653_13380	ENOG4106A3R	peptidase
I653_13385	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
I653_13390	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
I653_13400	ENOG4106AR7	Spore coat protein
I653_13405	ENOG41068KH	stage VI sporulation protein D
I653_13410	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
I653_13415	ENOG4105D52	delta-aminolevulinic acid dehydratase
I653_13425	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
I653_13435	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
I653_13445	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
I653_13450	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
I653_13455	ENOG4108IUQ	atp-dependent protease
I653_13460	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
I653_13465	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
I653_13475	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
I653_13480	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
I653_13485	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
I653_13490	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
I653_13495	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
I653_13500	ENOG4108ZP8	Acetolactate synthase small subunit
I653_13505	ENOG4105C7K	acetolactate synthase
I653_13515	ENOG4105I4A	GCN5-related N-acetyltransferase
I653_13520	ENOG4107KM7	Heat induced stress protein YflT
I653_13525	ENOG4105M59	Phosphodiesterase, mj0936 family
I653_13530	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
I653_13535	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
I653_13540	ENOG4108XJQ	germination protein
I653_13545	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
I653_13550	ENOG41067TZ	transcriptional regulator, MarR family
I653_13555	ENOG4105PFC	Transcriptional regulator
I653_13565	ENOG4105E33	succinate dehydrogenase
I653_13575	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
I653_13590	ENOG4105CFH	Aspartokinase
I653_13595	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
I653_13600	ENOG4105K63	Thioredoxin
I653_13605	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
I653_13610	ENOG4105C10	Electron transfer flavoprotein
I653_13615	ENOG4105BZJ	Electron transfer flavoprotein
I653_13620	ENOG41060WC	Enoyl-CoA hydratase
I653_13625	ENOG4107Z3H	Transcriptional regulator, TetR family
I653_13630	ENOG4105CEY	Amp-dependent synthetase and ligase
I653_13640	ENOG4105C98	muts2 protein
I653_13645	ENOG4105DCG	PHP domain protein
I653_13660	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
I653_13665	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
I653_13670	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
I653_13680	ENOG4108RWN	rrna methyltransferase
I653_13685	ENOG41067MF	small acid-soluble spore protein
I653_13695	ENOG4105CQB	FAD linked oxidase domain protein
I653_13700	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
I653_13715	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
I653_13720	ENOG4105DRS	transport system, permease
I653_13735	ENOG4108MDK	Dehydrogenase
I653_13745	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
I653_13750	ENOG4105EF1	ribulokinase
I653_13760	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
I653_13765	ENOG4105CN9	Peptidase m42 family protein
I653_13775	ENOG410696E	Membrane
I653_13780	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
I653_13785	ENOG4105VJV	50s ribosomal protein L35
I653_13790	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
I653_13800	ENOG41067MG	lrgb family
I653_13810	ENOG4105DY9	regulatoR
I653_13815	ENOG4108HRK	Histidine kinase
I653_13820	ENOG4105U0R	haloacid dehalogenase-like hydrolase
I653_13825	ENOG4105C22	threonyL-tRNA synthetase
I653_13830	ENOG4108TDW	sporulation protein YtxC
I653_13850	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
I653_13855	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
I653_13860	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
I653_13865	ENOG4105KVH	Transcriptional regulator
I653_13870	ENOG4105F27	Major Facilitator
I653_13875	ENOG4105CV8	reductase
I653_13880	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
I653_13890	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
I653_13895	ENOG4105C2M	dna polymerase I
I653_13900	ENOG4105BZU	Histidine kinase
I653_13905	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
I653_13910	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
I653_13915	ENOG4108HMX	isocitrate dehydrogenase (NADP)
I653_13920	ENOG4105BZN	citrate synthase
I653_13930	ENOG4108REF	Sporulation integral membrane protein ytvi
I653_13935	ENOG4105FS0	cytoplasmic membrane protein
I653_13940	ENOG4105CA9	Pyruvate kinase
I653_13945	ENOG4105CTQ	phosphohexokinase
I653_13955	ENOG4108IEY	Carboxyl transferase domain
I653_13960	ENOG4105C6K	Malic enzyme
I653_13965	ENOG4105C0B	DNA polymerase III (alpha subunit)
I653_13970	ENOG4105VV2	
I653_13980	ENOG4106EVM	
I653_13985	ENOG4105SFS	phosphoesterase RecJ domain protein
I653_14000	ENOG410635A	Membrane
I653_14005	ENOG4105CH2	amidohydrolase
I653_14025	ENOG4105DEN	Luciferase family
I653_14030	ENOG4105CDA	abc transporter atp-binding protein
I653_14055	ENOG4108XSB	acetyltransferase, (GNAT) family
I653_14060	ENOG4108KSA	LysR family transcriptional regulator
I653_14065	ENOG4105E8R	UPF0173 metal-dependent hydrolase
I653_14080	ENOG4105CH7	arginosuccinase
I653_14085	ENOG4105CDH	Citrulline--aspartate ligase
I653_14090	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
I653_14095	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
I653_14105	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
I653_14110	ENOG4105KBJ	sporulation protein ytfj
I653_14120	ENOG4105VK3	rdd domain containing protein
I653_14125	ENOG4105D07	Signal peptide peptidase, SppA
I653_14135	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
I653_14140	ENOG4105EFZ	amidohydrolase
I653_14145	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
I653_14180	ENOG4105U5Y	Transcriptional regulator
I653_14190	ENOG4105BZU	Histidine kinase
I653_14195	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
I653_14205	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
I653_14215	ENOG4105F1V	Acetoin utilization protein
I653_14220	ENOG4105W87	Cbs domain
I653_14225	ENOG4105DGU	Histone deacetylase
I653_14230	ENOG4105ER2	Ompa motb domain protein
I653_14235	ENOG4107R0U	MotA TolQ exbB proton channel
I653_14240	ENOG4105ETE	Transcriptional regulator (LacI family
I653_14245	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
I653_14265	ENOG4105DFU	Cell wall formation (By similarity)
I653_14275	ENOG4108VDD	TRNA binding domain protein
I653_14290	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
I653_14305	ENOG4105C6K	Malic enzyme
I653_14310	ENOG4105C8F	Beta-lactamase domain protein
I653_14315	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
I653_14325	ENOG4108V15	phosphotransferase enzyme family
I653_14330	ENOG4108IUM	Glycogen debranching enzyme
I653_14345	ENOG4107F58	2'-5' rna ligase
I653_14350	ENOG4105C6T	cysteine synthase
I653_14355	ENOG4107QSE	Dipeptidase
I653_14360	ENOG4105C7N	Xanthine uracil vitamin C permease
I653_14375	ENOG4105YW5	deoR family transcriptional regulator
I653_14390	ENOG4105CBX	hi0933 family
I653_14395	ENOG4105C94	Transporter
I653_14405	ENOG4105MU9	integral membrane protein
I653_14410	ENOG4105DDC	Oxidoreductase domain protein
I653_14420	ENOG4105F5H	Glycosyl Hydrolase Family 88
I653_14430	ENOG41075H3	AraC family transcriptional regulator
I653_14440	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
I653_14450	ENOG4106A3M	Cytochrome p-450
I653_14455	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
I653_14465	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
I653_14470	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
I653_14480	ENOG4105NTD	Inherit from COG: Hydrolase
I653_14495	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
I653_14500	ENOG4105I1K	ABC transporter
I653_14510	ENOG41085GJ	domain protein
I653_14515	ENOG4105C8T	Leucyl-tRNA synthetase
I653_14525	ENOG4105BZU	Histidine kinase
I653_14540	ENOG4106UBQ	
I653_14550	ENOG4105C19	ABC transporter
I653_14555	ENOG4105EWM	Histidine kinase
I653_14565	ENOG4107R34	abc transporter permease protein
I653_14570	ENOG4105C19	ABC transporter
I653_14585	ENOG4105DVE	abc transporter atp-binding protein
I653_14590	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
I653_14605	ENOG4105N5T	Radical SAM Protein
I653_14620	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
I653_14625	ENOG4108Z0R	Transferase
I653_14630	ENOG4105C85	amino acid
I653_14635	ENOG4105CAQ	asparagine synthetase
I653_14640	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
I653_14645	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
I653_14660	ENOG4105D2X	ABC transporter substrate-binding protein
I653_14670	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
I653_14685	ENOG4108RMU	ferritin dps family protein
I653_14700	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
I653_14705	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
I653_14710	ENOG4108V2W	Carbonate dehydratase
I653_14735	ENOG4105CC5	ABC transporter
I653_14740	ENOG4105CC5	ABC transporter
I653_14745	ENOG4105DIK	(ABC) transporter
I653_14750	ENOG4105DSE	periplasmic solute binding protein
I653_14755	ENOG4105DTQ	mandelate racemase muconate lactonizing
I653_14760	ENOG4105CEY	Amp-dependent synthetase and ligase
I653_14765	ENOG4108IPT	Naphthoate synthase
I653_14770	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
I653_14775	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
I653_14780	ENOG4105E4F	Isochorismate synthase
I653_14805	ENOG4108IAJ	Nad-dependent epimerase dehydratase
I653_14810	ENOG4107SBE	Glycosyl transferase (Group 1
I653_14825	ENOG4107SBE	Glycosyl transferase (Group 1
I653_14830	ENOG4108KS4	Spore coat protein
I653_14845	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
I653_14855	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
I653_14875	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
I653_14880	ENOG4105VRR	gCN5-related N-acetyltransferase
I653_14885	ENOG4105VRR	gCN5-related N-acetyltransferase
I653_14890	ENOG4105DZ6	Band 7 protein
I653_14900	ENOG4106DF1	
I653_14905	ENOG4108VNY	MOSC domain protein
I653_14910	ENOG4108JB8	alcohol dehydrogenase
I653_14915	ENOG4105C26	Dehydrogenase
I653_14920	ENOG4105TRT	Transcriptional regulator
I653_14935	ENOG4105CZN	Potassium uptake protein
I653_14940	ENOG4107I77	yiaA/B two helix domain
I653_14945	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
I653_14960	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
I653_14970	ENOG4105EE0	oxidoreductase
I653_14975	ENOG4105DKG	l-rhamnose isomerase
I653_14980	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
I653_14985	ENOG4105DET	Rhamnulokinase
I653_14990	ENOG4105E98	transcriptional regulator DeoR family
I653_15005	ENOG4105C8Q	Methyl-accepting chemotaxis
I653_15010	ENOG4105C8Q	Methyl-accepting chemotaxis
I653_15015	ENOG4105C8Q	Methyl-accepting chemotaxis
I653_15020	ENOG4105C8Q	Methyl-accepting chemotaxis
I653_15035	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
I653_15045	ENOG4105C37	(CBS) domain
I653_15060	ENOG4107PBV	potassium channel
I653_15065	ENOG4107PBV	potassium channel
I653_15080	ENOG4107QYV	phosphohexose isomerase
I653_15090	ENOG4107QW4	alcohol dehydrogenase
I653_15100	ENOG4105WG9	Conserved Protein
I653_15110	ENOG4105CHM	Aminotransferase
I653_15115	ENOG4108ZB6	transcriptional regulator AsnC family
I653_15120	ENOG4108MUZ	hydrolase
I653_15130	ENOG4105C87	Aminotransferase class I and II
I653_15135	ENOG4108HGU	Histidine kinase
I653_15140	ENOG4105Y38	Kinase-associated protein B
I653_15160	ENOG4105BZ4	penicillin-binding protein
I653_15165	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
I653_15180	ENOG4108MRH	transcriptional regulatory protein
I653_15185	ENOG4105DIH	basic membrane
I653_15190	ENOG4108JQ9	ABC transporter
I653_15195	ENOG4105UIB	(ABC) transporter
I653_15215	ENOG4105D65	subunit l
I653_15220	ENOG4105HC0	Na H antiporter
I653_15225	ENOG4108ZE9	Monovalent cation H antiporter subunit C
I653_15230	ENOG4108JPZ	Monovalent cation H antiporter subunit D
I653_15235	ENOG4105SC1	monovalent cation H antiporter subunit E
I653_15245	ENOG4105KJM	monovalent cation h antiporter subunit g
I653_15250	ENOG4105KA0	thioesterase Superfamily protein
I653_15260	ENOG4105BZU	Histidine kinase
I653_15285	ENOG4105D58	Diguanylate phosphodiesterase
I653_15290	ENOG4105DAP	Nicotinate phosphoribosyltransferase
I653_15315	ENOG4105C02	permease
I653_15335	ENOG410904N	short-chain dehydrogenase reductase
I653_15375	ENOG4108K8K	Transcriptional regulator
I653_15380	ENOG4105DCF	alanine dehydrogenase
I653_15390	ENOG4105WQT	MbtH domain protein
I653_15395	ENOG4105CEY	Amp-dependent synthetase and ligase
I653_15400	ENOG4105WQI	isochorismatase
I653_15405	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
I653_15410	ENOG4105E4F	Isochorismate synthase
I653_15415	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
I653_15420	ENOG4105NIV	Esterase
I653_15440	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
I653_15450	ENOG41069ER	domain protein
I653_15465	ENOG4105CEP	NADH dehydrogenase
I653_15470	ENOG4105CAY	ferredoxin--nadp reductase
I653_15490	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
I653_15495	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
I653_15510	ENOG4105ZKE	UPF0349 protein
I653_15525	ENOG41083MR	nifu domain-containing protein
I653_15530	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
I653_15535	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
I653_15540	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
I653_15545	ENOG4105D6E	homoserine dehydrogenase
I653_15555	ENOG4108W5N	phosphatidylglycerophosphatase a
I653_15560	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
I653_15570	ENOG4105MMD	transcriptional regulator
I653_15575	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
I653_15580	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
I653_15585	ENOG4105FAA	peptidase M23
I653_15590	ENOG4108YTE	sporulation protein YunB
I653_15595	ENOG4105KZD	Domain of unknown function (DUF1805)
I653_15600	ENOG4107R8B	5'-nucleotidase
I653_15610	ENOG4105I3N	Conserved Protein
I653_15620	ENOG4105CD3	dihydroorotase
I653_15625	ENOG4105G9B	Transcriptional regulator
I653_15640	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
I653_15645	ENOG4105VT2	5-hydroxyisourate hydrolase
I653_15660	ENOG4107YV9	domain protein
I653_15665	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
I653_15680	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
I653_15685	ENOG4105C5R	Aminotransferase
I653_15695	ENOG4108K8S	endonuclease I
I653_15700	ENOG4108IJ9	(ABC) transporter
I653_15705	ENOG4105FDP	GntR family transcriptional regulator
I653_15710	ENOG4108KPW	sugar kinase
I653_15715	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
I653_15720	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
I653_15725	ENOG4105XN3	extracellular solute-binding protein family 1
I653_15730	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
I653_15735	ENOG4105PKS	Excinuclease abc c subunit domain protein
I653_15740	ENOG4107VFR	oxidoreductase
I653_15755	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_15760	ENOG4105NPE	arsR family transcriptional regulator
I653_15765	ENOG4105DIW	FeS assembly protein SUFB
I653_15770	ENOG4108UNV	SUF system FeS assembly protein, NifU family
I653_15775	ENOG4105C9B	Cysteine desulfurase
I653_15780	ENOG4105JRK	feS assembly protein SufD
I653_15785	ENOG4105C3K	feS assembly ATPase SufC
I653_15800	ENOG4105D01	(LipO)protein
I653_15805	ENOG4108UMI	ABC transporter, permease
I653_15810	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
I653_15840	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
I653_15845	ENOG41080E8	Transcriptional regulator, Spx MgsR family
I653_15850	ENOG4105C1G	acyl-Coa dehydrogenase
I653_15855	ENOG4105CHU	acetyl-coa acetyltransferase
I653_15885	ENOG41067TZ	transcriptional regulator, MarR family
I653_15890	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
I653_15895	ENOG4105MDS	4-oxalocrotonate tautomerase
I653_15905	ENOG4105EGI	Transcriptional regulator
I653_15915	ENOG4105E0A	ABC, transporter
I653_15930	ENOG4105E1F	short-chain dehydrogenase reductase
I653_15935	ENOG4105HUF	DNA protection during starvation protein
I653_15940	ENOG4105C0H	protease
I653_15950	ENOG4105F3H	Histidine kinase
I653_15960	ENOG41067SE	Tetr family transcriptional regulator
I653_15965	ENOG4105C9Q	fumarate hydratase class II
I653_15990	ENOG4105WH1	Two component transcriptional regulator luxr family
I653_15995	ENOG4105ENE	Histidine kinase
I653_16010	ENOG41087YS	Phage shock protein A
I653_16035	ENOG4108WBT	adenosyltransferase
I653_16040	ENOG4105E0A	ABC, transporter
I653_16045	ENOG4105EHG	Permease protein
I653_16050	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
I653_16055	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
I653_16060	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
I653_16070	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
I653_16080	ENOG4106DF4	Sigma-70, region 4
I653_16090	ENOG4105F0F	Oxalate decarboxylase
I653_16100	ENOG4107RBB	ABC transporter, permease
I653_16105	ENOG4105C19	ABC transporter
I653_16110	ENOG4108WMK	Efflux transporter RND family MFP subunit
I653_16115	ENOG4105E0A	ABC, transporter
I653_16120	ENOG4105EHG	Permease protein
I653_16125	ENOG4105DQ5	transport system permease protein
I653_16135	ENOG4105D5Q	Arginine ornithine antiporter
I653_16145	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
I653_16150	ENOG4107QZ2	Sulfatase
I653_16155	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
I653_16160	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
I653_16165	ENOG4105E0C	molybdate abc transporter
I653_16180	ENOG4105EEQ	Na H antiporter
I653_16185	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
I653_16190	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
I653_16195	ENOG4105EEM	helicase
I653_16205	ENOG4105EN6	Membrane
I653_16215	ENOG4107ZQN	disulfide bond
I653_16220	ENOG4105C59	p-type ATPase
I653_16225	ENOG4105C59	p-type ATPase
I653_16230	ENOG410681U	heavy metal transport detoxification protein
I653_16235	ENOG4105VPX	protein, conserved in bacteria
I653_16240	ENOG4105D9R	oxidoreductase
I653_16245	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
I653_16250	ENOG4105ME7	Membrane
I653_16255	ENOG4105RXJ	
I653_16260	ENOG4105KPY	Small multidrug resistance protein
I653_16265	ENOG4105KBX	Transcriptional regulator, TetR family
I653_16270	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
I653_16275	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
I653_16280	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
I653_16290	ENOG4105XZU	Preprotein translocase, subunit SecG
I653_16315	ENOG4105KVH	Transcriptional regulator
I653_16335	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
I653_16340	ENOG4105R40	Glycine betaine carnitine choline
I653_16345	ENOG4108HQR	Glycine betaine
I653_16350	ENOG4105E90	ABC transporter
I653_16355	ENOG4108IJ8	ABC transporter
I653_16360	ENOG4107HG4	Transcriptional regulator
I653_16365	ENOG4105R40	Glycine betaine carnitine choline
I653_16370	ENOG4108HQR	Glycine betaine
I653_16375	ENOG4105E90	ABC transporter
I653_16380	ENOG4108IJ8	ABC transporter
I653_16385	ENOG4107HG4	Transcriptional regulator
I653_16390	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
I653_16395	ENOG4108QCI	YvbH-like oligomerisation region
I653_16405	ENOG4105T65	Membrane-associated protein
I653_16410	ENOG4108W0I	acetyltransferase
I653_16425	ENOG4105FJR	Lmbe family
I653_16445	ENOG4108IAJ	Nad-dependent epimerase dehydratase
I653_16450	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
I653_16455	ENOG4107QQG	Dehydrogenase
I653_16460	ENOG4105IIU	Aminopeptidase
I653_16465	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
I653_16470	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
I653_16475	ENOG4105CP7	Triose-phosphate isomerase
I653_16480	ENOG4105BZA	Phosphoglycerate kinase
I653_16490	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
I653_16505	ENOG4105CMD	Transcriptional regulator, GntR family
I653_16510	ENOG4105DEN	Luciferase family
I653_16515	ENOG4105GZI	Transcriptional regulator
I653_16520	ENOG4107RT3	EamA-like transporter family
I653_16530	ENOG4105VRS	hydrolase family 18
I653_16535	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
I653_16540	ENOG4107QR9	Iron-sulfur cluster binding protein
I653_16545	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
I653_16555	ENOG4105BZU	Histidine kinase
I653_16560	ENOG4105KCT	ABC transporter
I653_16565	ENOG4108M15	ABC transporter
I653_16570	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
I653_16575	ENOG4108MJI	response regulator
I653_16590	ENOG4105EG2	ABC transporter, permease
I653_16600	ENOG4107FKK	extracellular solute-binding protein family 1
I653_16610	ENOG4105JXH	GntR family transcriptional regulator
I653_16615	ENOG4105DAA	L-lactate
I653_16620	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I653_16630	ENOG4108ZPC	Polysaccharide pyruvyl transferase
I653_16635	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
I653_16640	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
I653_16645	ENOG4105D3Q	Sugar transferase
I653_16655	ENOG4105K64	Glycosyl transferase, family 2
I653_16665	ENOG4107QRS	glycosyltransferase group 2 family protein
I653_16670	ENOG41068W6	Capsular polysaccharide biosynthesis protein
I653_16675	ENOG4108KMV	Glycosyl transferase (Group 1
I653_16680	ENOG4105K64	Glycosyl transferase, family 2
I653_16685	ENOG4108PQP	glycosyl transferase group 1
I653_16695	ENOG4108QV3	biosynthesis protein
I653_16700	ENOG4105HTX	biosynthesis protein
I653_16710	ENOG4105EBR	Carboxylesterase
I653_16720	ENOG4105PY6	Phenolic acid decarboxylase
I653_16725	ENOG4105NI3	Protein of unknown function (DUF3237)
I653_16750	ENOG4105EDQ	levansucrase EC 2.4.1.10
I653_16755	ENOG4108HKT	sucrose-6-phosphate hydrolase
I653_16760	ENOG4107QTZ	amino acid
I653_16810	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
I653_16815	ENOG4107URF	beta-phospho-glucomutase
I653_16820	ENOG4105CG3	alpha amylase, catalytic region
I653_16835	ENOG4105EG2	ABC transporter, permease
I653_16840	ENOG4105D56	permease protein
I653_16845	ENOG4107FKK	extracellular solute-binding protein family 1
I653_16850	ENOG4108IUK	alpha amylase, catalytic
I653_16855	ENOG4105FKQ	transcriptional regulator
I653_16860	ENOG4108URH	decarboxylase
I653_16865	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
I653_16870	ENOG4105CHH	sulfate transporter
I653_16875	ENOG4108V2W	Carbonate dehydratase
I653_16880	ENOG4105C5I	Dehydrogenase
I653_16890	ENOG4105C19	ABC transporter
I653_16895	ENOG4105EWM	Histidine kinase
I653_16905	ENOG4107A6P	
I653_16910	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
I653_16915	ENOG4105KRI	phosphocarrier protein (HPr
I653_16920	ENOG4105CIE	May be required for sporulation (By similarity)
I653_16925	ENOG4105CHW	UPF0052 protein
I653_16930	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
I653_16935	ENOG4108Z4K	mutator MutT protein
I653_16940	ENOG4105C3M	thioredoxin reductase
I653_16955	ENOG4105BZ1	(ABC) transporter
I653_16965	ENOG4106FGC	
I653_16975	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
I653_16980	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
I653_16985	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
I653_16990	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
I653_16995	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
I653_17000	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
I653_17005	ENOG4107RN8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
I653_17010	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
I653_17020	ENOG4108E16	pectate lyase
I653_17025	ENOG4108S4C	acetyltransferase
I653_17030	ENOG4107XGZ	Hydrolase
I653_17035	ENOG4105HKU	nucleoside recognition domain-containing protein
I653_17050	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
I653_17055	ENOG4105CE4	GlcNAc 6-P deacetylase
I653_17060	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
I653_17065	ENOG4105FDP	GntR family transcriptional regulator
I653_17070	ENOG41088CQ	domain protein
I653_17075	ENOG41086DT	Membrane protein of unknown function
I653_17080	ENOG41067S9	phage shock protein C, PspC
I653_17085	ENOG4108PY7	
I653_17100	ENOG4105I03	Flagellin
I653_17110	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
I653_17115	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
I653_17130	ENOG4105MKU	Transcriptional regulator
I653_17150	ENOG4105CN1	protease
I653_17155	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
I653_17160	ENOG4105CAK	Cell division ATP-binding protein ftsE
I653_17175	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
I653_17185	ENOG4105MS2	ribosomal subunit Interface protein
I653_17200	ENOG4105MQ3	flagellar protein FliS
I653_17205	ENOG4107RT6	flagellar hook-associated
I653_17210	ENOG41083S7	flagellar protein FlaG
I653_17215	ENOG4105I03	Flagellin
I653_17220	ENOG41085Y9	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
I653_17225	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
I653_17230	ENOG4105MKD	
I653_17235	ENOG4105DTJ	flagellar hook-associated protein
I653_17240	ENOG4105E1Q	flagellar hook-associated protein
I653_17255	ENOG4105RU3	
I653_17260	ENOG41081UC	Inherit from COG: Competence protein
I653_17280	ENOG4105WH1	Two component transcriptional regulator luxr family
I653_17285	ENOG4105BZU	Histidine kinase
I653_17290	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
I653_17295	ENOG4108KGH	TRANSCRIPTIONal
I653_17300	ENOG4105ESV	Glycosyl transferase, family 4
I653_17305	ENOG4107EF8	Glycosyl transferase (Group 1
I653_17320	ENOG4105QZI	O-Antigen Polymerase
I653_17325	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
I653_17330	ENOG4107RA4	Glycosyl transferase (Group 1
I653_17335	ENOG4105PSV	Polysaccharide Biosynthesis Protein
I653_17340	ENOG4105D3Q	Sugar transferase
I653_17350	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
I653_17355	ENOG4105JFG	SpoIID LytB domain protein
I653_17370	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
I653_17390	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
I653_17395	ENOG4105EY8	ABC transporter
I653_17420	ENOG41088M2	Glycosyl transferase family 2
I653_17470	ENOG4105DG6	mannose-6-phosphate isomerase
I653_17485	ENOG4108NHD	germination protein
I653_17490	ENOG4105C54	Major Facilitator superfamily
I653_17495	ENOG4108KGH	TRANSCRIPTIONal
I653_17500	ENOG4105J7I	hydrolase
I653_17505	ENOG4105K4H	Nlp p60 protein
I653_17515	ENOG4105PNM	synthesis protein
I653_17525	ENOG4105N98	Capsule biosynthesis protein capB
I653_17530	ENOG4105ETE	Transcriptional regulator (LacI family
I653_17535	ENOG4108RVA	ribokinase
I653_17540	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
I653_17545	ENOG4105C2J	ABC transporter
I653_17550	ENOG4105CNN	ABC, transporter
I653_17555	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
I653_17570	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
I653_17575	ENOG4107FQX	Alpha-acetolactate decarboxylase
I653_17585	ENOG4107RSM	transcriptional regulator
I653_17600	ENOG4106UIA	
I653_17615	ENOG4107XC4	flavin reductase domain protein, FMN-binding
I653_17625	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
I653_17635	ENOG4105CAH	Chromate
I653_17640	ENOG4105FGV	Chromate
I653_17645	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
I653_17675	ENOG4108XI2	Domain of unknown function (DUF1963)
I653_17680	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
I653_17685	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
I653_17690	ENOG4107YJ4	chain length determinant protein
I653_17695	ENOG4105HTX	biosynthesis protein
I653_17705	ENOG4105KBK	Zinc finger, swim domain protein
I653_17710	ENOG4105C0D	helicase
I653_17715	ENOG410667J	hydrolase
I653_17720	ENOG4105E98	transcriptional regulator DeoR family
I653_17725	ENOG4105Z8H	single-stranded DNA-binding protein
I653_17750	ENOG4108VAC	response regulator
I653_17760	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
I653_17765	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
I653_17775	ENOG4105CGA	flagellar basal-body rod protein FlgG
I653_17785	ENOG4105DFF	Rod shape-determining protein mreb
I653_17790	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
I653_17795	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
I653_17800	ENOG4105CZM	Major Facilitator
I653_17805	ENOG4108M26	parallel beta-helix repeat protein
I653_17810	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
I653_17815	ENOG41080V3	Major Facilitator superfamily
I653_17820	ENOG4105D3W	isochorismatase
I653_17825	ENOG4107P26	
I653_17830	ENOG4105BZU	Histidine kinase
I653_17840	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
I653_17850	ENOG4105FRN	stage II sporulation protein
I653_17855	ENOG4107TCE	N-acetyltransferase
I653_17880	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
I653_17885	ENOG4107TXC	Transcriptional regulator
I653_17890	ENOG4106BRK	
I653_17895	ENOG4108RYK	Nad-dependent epimerase dehydratase
I653_17900	ENOG4108Z40	Transcriptional regulator
I653_17905	ENOG4105CQM	Urea amidohydrolase subunit alpha
I653_17910	ENOG4105KI2	Urea amidohydrolase subunit beta
I653_17915	ENOG4108YZ9	Urea amidohydrolase subunit gamma
I653_17950	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
I653_17960	ENOG4108TF4	von Willebrand factor, type A
I653_17975	ENOG4105JFG	SpoIID LytB domain protein
I653_17980	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
I653_17990	ENOG4106778	Protein of unknown function (DUF1146)
I653_18000	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
I653_18005	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
I653_18010	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
I653_18015	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
I653_18035	ENOG4107RB6	it plays a direct role in the translocation of protons across the membrane (By similarity)
I653_18045	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
I653_18050	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
I653_18055	ENOG4108UIC	UPF0340 protein
I653_18060	ENOG4108YZG	isomerase
I653_18065	ENOG4107WAU	Protein tyrosine phosphatase
I653_18070	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
I653_18075	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
I653_18085	ENOG4108ZXQ	stage ii sporulation protein r
I653_18100	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
I653_18105	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
I653_18110	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
I653_18120	ENOG4107TT2	Auxin Efflux Carrier
I653_18125	ENOG4105C6K	Malic enzyme
I653_18130	ENOG4107104	thymidine kinase
I653_18135	ENOG41082DI	50s ribosomal protein l31
I653_18140	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
I653_18145	ENOG4105CBT	Fructose-1,6-bisphosphatase
I653_18150	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
I653_18160	ENOG4107XMI	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I653_18165	ENOG4105D2N	Aldolase
I653_18170	ENOG410812K	response regulator receiver protein
I653_18180	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
I653_18190	ENOG4105C1G	acyl-Coa dehydrogenase
I653_18195	ENOG4105DF6	Fe-S oxidoreductase
I653_18205	ENOG4105E5J	UV damage endonuclease
I653_18215	ENOG4105NAE	bifunctional deaminase-reductase domain protein
I653_18220	ENOG4105BZ1	(ABC) transporter
I653_18225	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
I653_18235	ENOG4105R3A	Nitrate reductase
I653_18240	ENOG4108IUE	nitrate reductase beta subunit
I653_18260	ENOG4107V6Q	Cyclic nucleotide-binding domain
I653_18270	ENOG4105C75	arginyL-tRNA synthetase
I653_18275	ENOG410684U	Domain of unknown function (DUF1934)
I653_18285	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
I653_18335	ENOG4107JM4	Tetratricopeptide repeat
I653_18365	ENOG4108RDQ	ABC transporter
I653_18375	ENOG4105CYW	agmatinase
I653_18380	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
I653_18385	ENOG4105BZ4	penicillin-binding protein
I653_18390	ENOG4108XFG	YwhD family
I653_18395	ENOG4108Z4T	Peptidase M50
I653_18400	ENOG41069HH	4-oxalocrotonate tautomerase
I653_18405	ENOG41067TZ	transcriptional regulator, MarR family
I653_18410	ENOG4105C22	threonyL-tRNA synthetase
I653_18425	ENOG4105C57	major facilitator superfamily
I653_18430	ENOG41062ES	Transcriptional regulator
I653_18440	ENOG4105DCI	Phosphohydrolase
I653_18450	ENOG4108VCI	transcription factor, rsfa family
I653_18455	ENOG4108RNG	Permease of the drug metabolite transporter
I653_18465	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
I653_18470	ENOG4105DUM	transcriptional regulator, lysR family
I653_18475	ENOG4108IJ2	phosphate acetyltransferase
I653_18490	ENOG4105CHM	Aminotransferase
I653_18500	ENOG4108V3M	Inherit from COG: acetyl-CoA carboxylase biotin carboxylase
I653_18505	ENOG4105CHR	reductase
I653_18510	ENOG4106CHD	Bacilysin biosynthesis protein bacB
I653_18515	ENOG41061WN	bacilysin biosynthesis protein
I653_18520	ENOG4105FCW	Major Facilitator superfamily
I653_18535	ENOG4105C26	Dehydrogenase
I653_18540	ENOG4105D82	Glutamate dehydrogenase
I653_18550	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
I653_18555	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
I653_18560	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
I653_18565	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
I653_18570	ENOG4107P9E	Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG
I653_18575	ENOG4107TY6	Acylneuraminate cytidylyltransferase
I653_18585	ENOG41067MN	Spore coat polysaccharide biosynthesis protein spsD
I653_18590	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
I653_18625	ENOG4105C26	Dehydrogenase
I653_18630	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
I653_18635	ENOG4108RJ9	Glycosyl transferase, family 2
I653_18640	ENOG4105DWF	phosphomethylpyrimidine kinase
I653_18655	ENOG4105C5Y	PTS System
I653_18660	ENOG4108QTI	)-transporter
I653_18665	ENOG4108QTI	)-transporter
I653_18680	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
I653_18685	ENOG4105DEN	Luciferase family
I653_18690	ENOG4108DBC	nitroreductase
I653_18705	ENOG41060D1	Quinol oxidase
I653_18710	ENOG4105CCU	oxidase (Subunit III)
I653_18715	ENOG4105BZ9	Cytochrome C oxidase, subunit I
I653_18720	ENOG4105E2S	oxidase) subunit II
I653_18725	ENOG4107BMA	Transglycosylase associated protein
I653_18735	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
I653_18740	ENOG4105WH5	Teichoic acid glycosylation protein
I653_18765	ENOG4107ZXU	DSBA oxidoreductase
I653_18770	ENOG4105DBE	peroxidase
I653_18775	ENOG410650H	(LipO)protein
I653_18780	ENOG4107SJW	iron permease, FTR1
I653_18785	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
I653_18795	ENOG4105CMU	LysR family (Transcriptional regulator
I653_18800	ENOG4105VAW	lrga family
I653_18805	ENOG41067MG	lrgb family
I653_18810	ENOG4105D8G	Major Facilitator superfamily
I653_18820	ENOG4105DR4	Methyltransferase
I653_18840	ENOG4105CK1	PTS System
I653_18845	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
I653_18860	ENOG4105X1N	Glycosyl transferase family 8
I653_18870	ENOG4105GVJ	transcriptional regulator
I653_18875	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
I653_18880	ENOG4105IIU	Aminopeptidase
I653_18890	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
I653_18900	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
I653_18905	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
I653_18915	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
I653_18920	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
I653_18925	ENOG4105CM2	brancheD-chain amino acid aminotransferase
I653_18930	ENOG4105F8D	glycoside hydrolase family 4
I653_18935	ENOG4105VCP	PTS System
I653_18940	ENOG4105CK1	PTS System
I653_18945	ENOG4105VZJ	PTS System
I653_18950	ENOG4105EMD	TRANSCRIPTIONal
I653_18960	ENOG4108VX5	3-methyladenine DNA glycosylase
I653_18965	ENOG4105CH6	catalase
I653_18980	ENOG4105DA5	(ABC) transporter
I653_18985	ENOG41069JR	
I653_19005	ENOG4105ETS	cytosine purines uracil thiamine allantoin
I653_19010	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
I653_19015	ENOG4108JJ8	(ABC) transporter
I653_19020	ENOG4108JJ9	ABC, transporter
I653_19025	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
I653_19030	ENOG4105C4M	(Ubiquinol oxidase) subunit I
I653_19035	ENOG4105D2K	citrate carrier protein
I653_19045	ENOG4107BJW	polysaccharide deacetylase
I653_19065	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
I653_19075	ENOG4105CMR	udp-glucose 4-epimerase
I653_19080	ENOG4105KIS	phospholipid-binding protein
I653_19085	ENOG4108WAV	Transcriptional regulator
I653_19095	ENOG4105BZU	Histidine kinase
I653_19100	ENOG4105WH1	Two component transcriptional regulator luxr family
I653_19105	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
I653_19135	ENOG4105DTD	Dehydrogenase
I653_19140	ENOG4108IIH	CoA-transferase subunit B
I653_19145	ENOG4105D6N	CoA-transferase, subunit a
I653_19150	ENOG4105CY2	Citrate transporter
I653_19155	ENOG4105DHI	Methyltransferase
I653_19175	ENOG4105CH6	catalase
I653_19180	ENOG4105D4T	Citrate transporter
I653_19185	ENOG4108RZ2	Glycoside hydrolase family 16
I653_19190	ENOG4105CID	antiterminator
I653_19200	ENOG4105DEU	major facilitator superfamily
I653_19205	ENOG4105C1J	atp-dependent rna helicase
I653_19210	ENOG4107TDE	lipolytic protein G-D-S-L family
I653_19235	ENOG4107YZX	Universal stress protein
I653_19240	ENOG4105CS2	ec 3.2.1.21
I653_19245	ENOG4105C5Y	PTS System
I653_19295	ENOG4107EV6	Inherit from COG: YD repeat protein
I653_19310	ENOG4108F3G	Type I restriction-modification system, R subunit
I653_19320	ENOG4105M6F	mutator MutT protein
I653_19325	ENOG4106Z5D	Glycoside Hydrolase Family 43
I653_19340	ENOG4105C84	Histidine ammonia-lyase
I653_19345	ENOG4105CGP	Urocanate hydratase
I653_19350	ENOG4105CI2	imidazolone-5-propionate hydrolase
I653_19355	ENOG4107W25	arginase agmatinase formiminoglutamase
I653_19365	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
I653_19370	ENOG4105D9N	nucleoside
I653_19380	ENOG4107RHR	regulatoR
I653_19385	ENOG4108TM9	integral membrane protein
I653_19390	ENOG4105ENY	Ethanolamine utilization protein eutH
I653_19395	ENOG4108PGP	mmge prpd family protein
I653_19400	ENOG4105CH2	amidohydrolase
I653_19410	ENOG4108HW4	amino acid AbC transporter
I653_19415	ENOG4105EAB	amino acid AbC transporter
I653_19420	ENOG4108XSB	acetyltransferase, (GNAT) family
I653_19425	ENOG4105CPU	Monooxygenase
I653_19430	ENOG4107QHE	Choloylglycine hydrolase
I653_19435	ENOG410667J	hydrolase
I653_19465	ENOG4108V5C	ABC transporter
I653_19495	ENOG4105D2N	Aldolase
I653_19500	ENOG4107TRN	Xylose isomerase domain protein TIM barrel
I653_19505	ENOG4105F0H	myo-inositol catabolism protein
I653_19510	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
I653_19520	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
I653_19525	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
I653_19530	ENOG4105D7K	pfkb domain protein
I653_19540	ENOG4105C26	Dehydrogenase
I653_19550	ENOG4105CPC	Aldo Keto reductase
I653_19565	ENOG4107QNK	)-transporter
I653_19570	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
I653_19580	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
I653_19585	ENOG4105ST3	Transcriptional regulator
I653_19590	ENOG4105C26	Dehydrogenase
I653_19595	ENOG41085PJ	rdd domain containing protein
I653_19600	ENOG4108ITS	PQQ enzyme repeat
I653_19610	ENOG41085PJ	rdd domain containing protein
I653_19625	ENOG4105J7D	transcriptional regulator
I653_19630	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
I653_19635	ENOG41061AU	MarR family Transcriptional regulator
I653_19645	ENOG41067MG	lrgb family
I653_19655	ENOG4105BZW	Glycerate kinase
I653_19660	ENOG4105G3Z	GntR family transcriptional regulator
I653_19665	ENOG4105CMG	Carbohydrate kinase
I653_19670	ENOG4105C6Z	Gluconate
I653_19675	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
I653_19680	ENOG4105D3R	alkyl hydroperoxide reductase
I653_19685	ENOG4108JU3	Alkyl hydroperoxide reductase
I653_19695	ENOG4105CS2	ec 3.2.1.21
I653_19705	ENOG4108S3Y	transcriptional regulator
I653_19715	ENOG4106KKU	
I653_19720	ENOG4108Z15	abc transporter atp-binding protein
I653_19725	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
I653_19735	ENOG4107QMH	DNA methylase
I653_19750	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
I653_19765	ENOG4105E2A	Dehydrogenase
I653_19785	ENOG4105NUN	Orthopoxvirus protein of unknown function (DUF830)
I653_19790	ENOG4105WQG	acetyltransferase
I653_19795	ENOG410780I	phosphoprotein phosphatase activity
I653_19805	ENOG41066UZ	arginase EC 3.5.3.1
I653_19810	ENOG4108IQI	permease
I653_19815	ENOG4105C8Y	Acetylornithine aminotransferase
I653_19820	ENOG4108JUB	Transcriptional regulator
I653_19825	ENOG4105BZU	Histidine kinase
I653_19830	ENOG4105C0H	protease
I653_19835	ENOG4105Q2H	domain protein
I653_19850	ENOG4105BZU	Histidine kinase
I653_19855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
I653_19860	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
I653_19865	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_19870	ENOG4105CDU	Replicative dna helicase
I653_19895	ENOG4105DJ2	Major Facilitator Superfamily
I653_19900	ENOG4105EDW	glycosyl transferase, family 39
I653_19905	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
I653_19910	ENOG4105BZR	domain protein
I653_19915	ENOG4108XMW	Membrane
I653_19930	ENOG4105KVH	Transcriptional regulator
I653_19935	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
I653_19955	ENOG41090E6	transcriptional regulator MERR family
I653_19965	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
I653_19970	ENOG4105DDN	Pentapeptide repeat-containing protein
I653_19975	ENOG4105D94	Major Facilitator Superfamily
I653_19980	ENOG4107RSM	transcriptional regulator
I653_19985	ENOG41082BV	acetyltransferase
I653_19990	ENOG41081I9	integral membrane protein
I653_19995	ENOG4107V2S	Transcriptional regulator
I653_20000	ENOG4108VP3	Lysine exporter protein (LysE YggA)
I653_20010	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_20020	ENOG4108U05	Transcriptional regulator
I653_20025	ENOG41082BV	acetyltransferase
I653_20035	ENOG4108U7W	acetyltransferase
I653_20040	ENOG4105UNS	Pfam:DUF419
I653_20045	ENOG4105NAE	bifunctional deaminase-reductase domain protein
I653_20050	ENOG4105C7Z	Conserved Protein
I653_20055	ENOG4108UXE	Protein tyrosine phosphatase
I653_20060	ENOG4105D6J	arsenicaL-resistance protein
I653_20065	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_20070	ENOG41085FC	arsR family transcriptional regulator
I653_20080	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
I653_20085	ENOG4105C7Z	Conserved Protein
I653_20090	ENOG4107FCW	Abortive infection protein
I653_20100	ENOG4108UW5	maltose o-acetyltransferase
I653_20105	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
I653_20115	ENOG4105CGK	Exodeoxyribonuclease III
I653_20120	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
I653_20125	ENOG4108UUM	single-stranded DNA-binding protein
I653_20130	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
I653_20135	ENOG4105C3G	gtp-binding protein
I653_20140	ENOG4108J2R	molybdopterin oxidoreductase
I653_20145	ENOG4105VDK	protein, conserved in bacteria
I653_20155	ENOG4108ZDA	Sporulation protein YyaC
I653_20160	ENOG4105FA0	parb-like partition protein
I653_20165	ENOG4107QJE	Chromosome Partitioning Protein
I653_20180	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
I653_20185	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
I653_20190	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
I653_20205	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)