locus-tag	class	description
A7A1_0000	COG1266	CAAX protease self-immunity
A7A1_0001	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A7A1_0002	COG0459	protein refolding
A7A1_0003	COG1073	alpha beta
A7A1_0004	COG0457	Tetratricopeptide repeat
A7A1_0005	COG1063	alcohol dehydrogenase
A7A1_0006	COG2211	Major facilitator Superfamily
A7A1_0007	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7A1_0008	COG1842	Phage shock protein A
A7A1_0009	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7A1_0010	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A7A1_0011	COG4260	virion core protein, lumpy skin disease virus
A7A1_0013	COG2814	Major facilitator Superfamily
A7A1_0014	COG1063	alcohol dehydrogenase
A7A1_0015	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A7A1_0016	COG0823	Involved in the tonB-independent uptake of proteins
A7A1_0018	COG2267	carboxylic ester hydrolase activity
A7A1_0020	COG2132	Multicopper oxidase
A7A1_0021	COG1113	amino acid transport
A7A1_0022	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7A1_0026	COG3677	Transposase
A7A1_0029	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A7A1_0030	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_0032	COG3711	transcriptional antiterminator
A7A1_0032	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A1_0033	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A1_0033	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A1_0033	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A1_0034	COG1482	cell wall glycoprotein biosynthetic process
A7A1_0036	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_0037	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7A1_0039	COG0109	protoheme IX farnesyltransferase activity
A7A1_0041	COG0726	polysaccharide deacetylase
A7A1_0044	COG5504	Zn-dependent protease
A7A1_0045	COG2205	protein histidine kinase activity
A7A1_0047	COG3383	formate dehydrogenase (NAD+) activity
A7A1_0048	COG2427	Protein of unknown function (DUF1641)
A7A1_0049	COG0726	polysaccharide deacetylase
A7A1_0050	COG2194	sulfuric ester hydrolase activity
A7A1_0052	COG0489	protein tyrosine kinase activity
A7A1_0053	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A1_0055	COG2226	methyltransferase
A7A1_0056	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A7A1_0057	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A7A1_0058	COG0101	tRNA pseudouridine synthase activity
A7A1_0059	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7A1_0060	COG1122	ATPase activity
A7A1_0061	COG1122	ATPase activity
A7A1_0062	COG0203	ribosomal protein L17
A7A1_0063	COG0202	RNA polymerase activity
A7A1_0064	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A7A1_0065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A7A1_0066	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A7A1_0067	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A7A1_0068	COG0024	Methionine aminopeptidase
A7A1_0069	COG0563	adenylate kinase activity
A7A1_0070	COG0201	protein transport
A7A1_0071	COG0200	Binds to the 23S rRNA
A7A1_0072	COG1841	ribosomal large subunit assembly
A7A1_0074	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A7A1_0075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A7A1_0076	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A7A1_0078	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7A1_0080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A7A1_0081	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A7A1_0082	COG0255	Belongs to the universal ribosomal protein uL29 family
A7A1_0083	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A7A1_0084	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A7A1_0085	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A7A1_0086	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A7A1_0087	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A7A1_0088	COG0089	rRNA binding
A7A1_0089	COG0088	Forms part of the polypeptide exit tunnel
A7A1_0090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A7A1_0091	COG0051	transcription antitermination factor activity, RNA binding
A7A1_0092	COG0596	Alpha beta hydrolase
A7A1_0093	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7A1_0094	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A7A1_0095	COG0049	tRNA binding
A7A1_0096	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A7A1_0097	COG1358	cellular component organization or biogenesis
A7A1_0098	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A7A1_0099	COG0085	RNA polymerase activity
A7A1_0100	COG2813	Specifically methylates the guanine in position
A7A1_0101	COG0222	ribosome binding
A7A1_0102	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A7A1_0103	COG0081	regulation of translation
A7A1_0104	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A7A1_0105	COG0250	Participates in transcription elongation, termination and antitermination
A7A1_0106	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7A1_0107	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A7A1_0108	COG1595	DNA-templated transcription, initiation
A7A1_0109	COG3688	RNA-binding protein containing a PIN domain
A7A1_0110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7A1_0111	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A7A1_0112	COG0215	cysteine-tRNA ligase activity
A7A1_0113	COG1045	serine acetyltransferase
A7A1_0114	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A7A1_0115	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A7A1_0116	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A7A1_0117	COG4956	integral membrane protein (PIN domain superfamily)
A7A1_0118	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
A7A1_0119	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A7A1_0120	COG0542	response to heat
A7A1_0121	COG3869	Catalyzes the specific phosphorylation of arginine residues in
A7A1_0122	COG3880	PFAM UvrB UvrC protein
A7A1_0123	COG4463	regulation of RNA biosynthetic process
A7A1_0124	COG0745	RESPONSE REGULATOR receiver
A7A1_0125	COG5002	protein histidine kinase activity
A7A1_0126	COG4863	YycH protein
A7A1_0127	COG4853	Protein conserved in bacteria
A7A1_0128	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A7A1_0129	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7A1_0133	COG0745	RESPONSE REGULATOR receiver
A7A1_0134	COG5002	protein histidine kinase activity
A7A1_0135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7A1_0136	COG0833	amino acid
A7A1_0137	COG0010	Belongs to the arginase family
A7A1_0138	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7A1_0139	COG4294	response to UV
A7A1_0141	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7A1_0142	COG1132	(ABC) transporter
A7A1_0143	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7A1_0144	COG2181	nitrate reductase activity
A7A1_0145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A7A1_0146	COG1140	nitrate reductase beta subunit
A7A1_0147	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A7A1_0148	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7A1_0150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7A1_0151	COG2223	nitrite transmembrane transporter activity
A7A1_0152	COG0018	arginyl-trna synthetase
A7A1_0153	COG4506	Protein conserved in bacteria
A7A1_0156	COG0535	radical SAM domain protein
A7A1_0158	COG1131	(ABC) transporter
A7A1_0159	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7A1_0160	COG0612	Peptidase, M16
A7A1_0161	COG0612	Peptidase, M16
A7A1_0163	COG3391	amine dehydrogenase activity
A7A1_0164	COG3391	amine dehydrogenase activity
A7A1_0165	COG0457	Tetratricopeptide repeat
A7A1_0167	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7A1_0168	COG0010	Belongs to the arginase family
A7A1_0169	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A7A1_0170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A1_0172	COG1994	Peptidase M50
A7A1_0173	COG1942	4-Oxalocrotonate Tautomerase
A7A1_0174	COG1846	Transcriptional regulator
A7A1_0175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7A1_0176	COG0477	Major facilitator Superfamily
A7A1_0177	COG1959	2 iron, 2 sulfur cluster binding
A7A1_0178	COG3465	dGTPase activity
A7A1_0179	COG1078	dGTPase activity
A7A1_0180	COG4844	belongs to the
A7A1_0182	COG0697	spore germination
A7A1_0183	COG0095	Lipoate-protein ligase
A7A1_0184	COG0583	DNA-binding transcription factor activity
A7A1_0185	COG0280	phosphate acetyltransferase
A7A1_0187	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_0188	COG0436	Aminotransferase
A7A1_0189	COG2814	Major facilitator Superfamily
A7A1_0190	COG0151	Belongs to the GarS family
A7A1_0191	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_0192	COG1917	Cupin 2, conserved barrel domain protein
A7A1_0193	COG0077	Prephenate dehydratase
A7A1_0194	COG2814	Major facilitator Superfamily
A7A1_0195	COG0833	amino acid
A7A1_0196	COG4187	Peptidase family M20/M25/M40
A7A1_0197	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_0198	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7A1_0200	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A7A1_0201	COG1091	dTDP-4-dehydrorhamnose reductase activity
A7A1_0202	COG1088	dTDP-glucose 4,6-dehydratase activity
A7A1_0203	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A7A1_0204	COG3980	spore coat polysaccharide biosynthesis protein
A7A1_0205	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
A7A1_0206	COG2089	acid synthase
A7A1_0207	COG0456	acetyltransferase
A7A1_0208	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A7A1_0209	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7A1_0210	COG0463	Glycosyl transferase, family 2
A7A1_0212	COG2363	Small membrane protein
A7A1_0213	COG2233	PERMEase
A7A1_0215	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_0216	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A7A1_0217	COG1216	Glycosyl transferase, family 2
A7A1_0220	COG1695	Transcriptional regulator
A7A1_0221	COG0351	phosphomethylpyrimidine kinase
A7A1_0223	COG1621	beta-fructofuranosidase activity
A7A1_0224	COG1263	PTS System
A7A1_0224	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_0225	COG2116	formate transmembrane transporter activity
A7A1_0226	COG3711	transcriptional antiterminator
A7A1_0228	COG1051	belongs to the nudix hydrolase family
A7A1_0230	COG2124	cytochrome p450
A7A1_0231	COG1819	glycosyl
A7A1_0232	COG1587	Uroporphyrinogen-III synthase
A7A1_0233	COG0390	transport system, permease component
A7A1_0234	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7A1_0235	COG0697	spore germination
A7A1_0236	COG4297	protein containing double-stranded beta helix domain
A7A1_0238	COG1252	NADH dehydrogenase
A7A1_0239	COG1904	glucuronate isomerase
A7A1_0240	COG2211	Major facilitator Superfamily
A7A1_0241	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A7A1_0242	COG1063	alcohol dehydrogenase
A7A1_0243	COG1312	Catalyzes the dehydration of D-mannonate
A7A1_0244	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_0245	COG2271	Major facilitator Superfamily
A7A1_0246	COG1609	Transcriptional regulator
A7A1_0247	COG0246	Mannitol dehydrogenase
A7A1_0248	COG2721	sulfolactate sulfo-lyase activity
A7A1_0249	COG0730	response to heat
A7A1_0250	COG2318	DinB family
A7A1_0251	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7A1_0252	COG0457	Tetratricopeptide repeat
A7A1_0254	COG2350	Protein conserved in bacteria
A7A1_0255	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_0255	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A1_0255	COG1388	LysM domain
A7A1_0257	COG4195	phage-related replication protein
A7A1_0258	COG3546	catalase activity
A7A1_0259	COG2856	Zn peptidase
A7A1_0260	COG1396	sequence-specific DNA binding
A7A1_0261	COG1522	sequence-specific DNA binding
A7A1_0262	COG1484	DNA-dependent DNA replication
A7A1_0265	COG1595	DNA-templated transcription, initiation
A7A1_0266	COG5484	DNA packaging
A7A1_0266	COG3728	DNA packaging
A7A1_0267	COG1783	phage Terminase large subunit
A7A1_0268	COG5518	Phage portal protein
A7A1_0269	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A7A1_0270	COG4653	Phage capsid family
A7A1_0278	COG0392	lysyltransferase activity
A7A1_0278	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A7A1_0279	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A1_0280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_0281	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_0282	COG0384	phenazine biosynthesis protein PhzF
A7A1_0283	COG0778	Nitroreductase
A7A1_0286	COG1090	epimerase
A7A1_0287	COG2137	regulation of response to DNA damage stimulus
A7A1_0289	COG2814	Major facilitator Superfamily
A7A1_0292	COG3103	Sh3 type 3 domain protein
A7A1_0293	COG5658	integral membrane protein
A7A1_0294	COG0596	Alpha beta hydrolase
A7A1_0295	COG0463	Glycosyl transferase, family 2
A7A1_0296	COG4485	Bacterial membrane protein, YfhO
A7A1_0297	COG1988	membrane-bound metal-dependent
A7A1_0298	COG1194	a g-specific adenine glycosylase
A7A1_0300	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_0303	COG3557	Belongs to the UPF0374 family
A7A1_0304	COG1132	(ABC) transporter
A7A1_0305	COG4129	membrane
A7A1_0306	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A7A1_0307	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7A1_0308	COG0735	belongs to the Fur family
A7A1_0311	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A7A1_0312	COG1074	ATP-dependent DNA helicase activity
A7A1_0313	COG0420	3'-5' exonuclease activity
A7A1_0314	COG0419	ATPase involved in DNA repair
A7A1_0315	COG1403	HNH endonuclease
A7A1_0323	COG5337	Spore coat protein CotH
A7A1_0324	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7A1_0326	COG1404	Belongs to the peptidase S8 family
A7A1_0328	COG2828	Protein conserved in bacteria
A7A1_0329	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_0330	COG5566	PFAM Mor transcription activator
A7A1_0332	COG0596	Alpha beta hydrolase
A7A1_0333	COG4991	sh3 domain protein
A7A1_0334	COG4991	sh3 domain protein
A7A1_0335	COG0346	lactoylglutathione lyase activity
A7A1_0337	COG5577	PFAM Coat F domain
A7A1_0338	COG1063	alcohol dehydrogenase
A7A1_0340	COG5577	PFAM Coat F domain
A7A1_0341	COG0789	Transcriptional regulator
A7A1_0342	COG1064	alcohol dehydrogenase
A7A1_0343	COG0693	protein deglycase activity
A7A1_0344	COG1621	beta-fructofuranosidase activity
A7A1_0345	COG3716	PTS system mannose fructose sorbose family IID component
A7A1_0346	COG3715	PTS system
A7A1_0347	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_0348	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A1_0349	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A7A1_0349	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A7A1_0350	COG1113	amino acid transport
A7A1_0351	COG1280	lysine exporter protein (LysE YggA)
A7A1_0352	COG1378	Sugar-specific transcriptional regulator TrmB
A7A1_0353	COG1595	DNA-templated transcription, initiation
A7A1_0355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A7A1_0355	COG2755	lipolytic protein G-D-S-L family
A7A1_0357	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A7A1_0357	COG2124	cytochrome p450
A7A1_0358	COG1309	transcriptional regulator
A7A1_0359	COG2226	methyltransferase
A7A1_0362	COG2116	formate transmembrane transporter activity
A7A1_0363	COG5609	conserved protein (DUF2294)
A7A1_0364	COG3383	formate dehydrogenase (NAD+) activity
A7A1_0365	COG2427	Protein of unknown function (DUF1641)
A7A1_0367	COG0626	cystathionine gamma-synthase activity
A7A1_0368	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7A1_0369	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A7A1_0370	COG2226	methyltransferase
A7A1_0373	COG0768	penicillin binding
A7A1_0374	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A7A1_0375	COG0572	uridine kinase
A7A1_0379	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A7A1_0380	COG3906	Belongs to the UPF0473 family
A7A1_0381	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A7A1_0382	COG4472	Bacterial protein of unknown function (DUF965)
A7A1_0383	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7A1_0384	COG0628	permease
A7A1_0385	COG1126	abc transporter atp-binding protein
A7A1_0386	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A1_0387	COG0765	amino acid transport
A7A1_0388	COG0765	amino acid transport
A7A1_0389	COG3881	PFAM PRC-barrel domain
A7A1_0390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7A1_0391	COG0457	Tetratricopeptide repeat
A7A1_0392	COG0482	sulfurtransferase activity
A7A1_0393	COG1104	cysteine desulfurase activity
A7A1_0394	COG1959	2 iron, 2 sulfur cluster binding
A7A1_0395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7A1_0396	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A7A1_0397	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A7A1_0398	COG0124	histidyl-tRNA synthetase
A7A1_0400	COG4991	sh3 domain protein
A7A1_0400	COG3103	Sh3 type 3 domain protein
A7A1_0400	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A1_0401	COG1490	D-aminoacyl-tRNA deacylase activity
A7A1_0402	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A7A1_0403	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7A1_0404	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A7A1_0404	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A7A1_0405	COG5416	Lipopolysaccharide assembly protein A domain
A7A1_0406	COG0490	domain, Protein
A7A1_0407	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7A1_0407	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7A1_0409	COG2244	polysaccharide biosynthetic process
A7A1_0410	COG2323	membrane
A7A1_0412	COG1862	Preprotein translocase
A7A1_0413	COG0343	queuine tRNA-ribosyltransferase activity
A7A1_0414	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A7A1_0415	COG2255	four-way junction helicase activity
A7A1_0416	COG0632	four-way junction helicase activity
A7A1_0418	COG2814	Major facilitator Superfamily
A7A1_0419	COG0673	inositol 2-dehydrogenase activity
A7A1_0420	COG2112	serine threonine protein kinase
A7A1_0422	COG1115	amino acid carrier protein
A7A1_0423	COG0217	transcriptional regulatory protein
A7A1_0425	COG1388	LysM domain
A7A1_0426	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A7A1_0427	COG0157	Belongs to the NadC ModD family
A7A1_0428	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7A1_0429	COG1104	cysteine desulfurase activity
A7A1_0430	COG1827	regulation of RNA biosynthetic process
A7A1_0431	COG0077	Prephenate dehydratase
A7A1_0432	COG4492	Belongs to the UPF0735 family
A7A1_0433	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7A1_0434	COG3290	protein histidine kinase activity
A7A1_0435	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A7A1_0436	COG2868	ribosomal protein
A7A1_0437	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A7A1_0438	COG1994	Peptidase M50
A7A1_0439	COG0739	heme binding
A7A1_0440	COG2894	cell division
A7A1_0441	COG0850	regulation of cytokinetic process
A7A1_0442	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A7A1_0443	COG1792	Involved in formation and maintenance of cell shape
A7A1_0444	COG1077	Cell shape determining protein MreB Mrl
A7A1_0445	COG2003	Belongs to the UPF0758 family
A7A1_0446	COG0424	maF-like protein
A7A1_0448	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A7A1_0449	COG0285	dihydrofolate synthase activity
A7A1_0450	COG0525	valine-tRNA ligase activity
A7A1_0452	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A1_0453	COG1388	LysM domain
A7A1_0454	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A7A1_0455	COG0113	porphobilinogen synthase activity
A7A1_0456	COG1587	Uroporphyrinogen-III synthase
A7A1_0457	COG0181	hydroxymethylbilane synthase activity
A7A1_0458	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7A1_0459	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A7A1_0461	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A7A1_0462	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7A1_0463	COG0470	DNA polymerase III
A7A1_0463	COG1067	ATP-dependent peptidase activity
A7A1_0464	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A7A1_0465	COG0544	peptidyl-prolyl cis-trans isomerase activity
A7A1_0466	COG1477	protein flavinylation
A7A1_0466	COG0457	Tetratricopeptide repeat
A7A1_0467	COG0066	3-isopropylmalate dehydratase activity
A7A1_0468	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A7A1_0469	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A7A1_0470	COG0284	orotidine-5'-phosphate decarboxylase activity
A7A1_0471	COG0167	dihydroorotate dehydrogenase activity
A7A1_0472	COG0543	2 iron, 2 sulfur cluster binding
A7A1_0473	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A7A1_0474	COG0505	Belongs to the CarA family
A7A1_0475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7A1_0476	COG0540	Belongs to the ATCase OTCase family
A7A1_0477	COG2233	PERMEase
A7A1_0478	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
A7A1_0479	COG0564	pseudouridine synthase activity
A7A1_0480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A7A1_0481	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A7A1_0482	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A7A1_0483	COG3599	regulation of cell shape
A7A1_0484	COG2302	S4 RNA-binding domain
A7A1_0485	COG0762	integral membrane protein
A7A1_0486	COG1799	cell septum assembly
A7A1_0487	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A7A1_0489	COG1873	PFAM PRC-barrel domain
A7A1_0490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7A1_0491	COG1119	ATPase activity
A7A1_0492	COG1191	sigma factor activity
A7A1_0493	COG1191	sigma factor activity
A7A1_0495	COG4412	M6 family metalloprotease domain protein
A7A1_0495	COG1404	Belongs to the peptidase S8 family
A7A1_0496	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7A1_0497	COG0849	cell division
A7A1_0498	COG3856	small basic protein
A7A1_0499	COG3879	Bacterial protein of unknown function (DUF881)
A7A1_0500	COG3879	Bacterial protein of unknown function (DUF881)
A7A1_0501	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A7A1_0502	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A7A1_0503	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A7A1_0504	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A7A1_0505	COG0772	Belongs to the SEDS family
A7A1_0506	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A7A1_0507	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7A1_0508	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A7A1_0509	COG0768	penicillin binding
A7A1_0511	COG4839	cell division protein FtsL
A7A1_0512	COG0275	rRNA processing
A7A1_0513	COG2001	Belongs to the MraZ family
A7A1_0514	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
A7A1_0515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7A1_0516	COG0454	-acetyltransferase
A7A1_0518	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A7A1_0519	COG1399	metal-binding, possibly nucleic acid-binding protein
A7A1_0520	COG1323	Belongs to the UPF0348 family
A7A1_0521	COG3480	Lon protease (S16) C-terminal proteolytic domain
A7A1_0522	COG1752	Esterase of the alpha-beta hydrolase superfamily
A7A1_0523	COG3314	Sporulation integral membrane protein YlbJ
A7A1_0524	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A7A1_0525	COG0742	ribosomal rna small subunit methyltransferase
A7A1_0526	COG4471	UPF0298 protein
A7A1_0527	COG3679	Belongs to the UPF0342 family
A7A1_0530	COG2340	Cysteine-rich secretory protein family
A7A1_0531	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A7A1_0533	COG3336	cytochrome c oxidase
A7A1_0534	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A7A1_0535	COG1845	cytochrome c oxidase, subunit III
A7A1_0536	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A7A1_0537	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A7A1_0537	COG2010	Cytochrome c
A7A1_0538	COG0109	protoheme IX farnesyltransferase activity
A7A1_0539	COG1612	heme a metabolic process
A7A1_0540	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A7A1_0541	COG0772	Belongs to the SEDS family
A7A1_0543	COG4838	Belongs to the UPF0358 family
A7A1_0544	COG2066	Belongs to the glutaminase family
A7A1_0545	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A7A1_0546	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A7A1_0548	COG4896	Protein conserved in bacteria
A7A1_0554	COG1595	DNA-templated transcription, initiation
A7A1_0558	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7A1_0560	COG0483	inositol monophosphate 1-phosphatase activity
A7A1_0562	COG4493	Belongs to the UPF0637 family
A7A1_0563	COG4476	Belongs to the UPF0223 family
A7A1_0564	COG1982	Orn Lys Arg decarboxylase major
A7A1_0565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_0566	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7A1_0567	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7A1_0568	COG0022	dehydrogenase e1 component
A7A1_0569	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7A1_0570	COG0497	DNA recombination
A7A1_0572	COG0242	peptide deformylase activity
A7A1_0573	COG0561	phosphatase activity
A7A1_0575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7A1_0576	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A7A1_0577	COG0569	domain protein
A7A1_0578	COG2105	PFAM AIG2 family protein
A7A1_0578	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A7A1_0579	COG3852	Histidine kinase
A7A1_0580	COG2002	toxin-antitoxin pair type II binding
A7A1_0581	COG1077	Cell shape determining protein MreB Mrl
A7A1_0583	COG1846	Transcriptional regulator
A7A1_0584	COG2814	Major facilitator Superfamily
A7A1_0585	COG2318	DinB family
A7A1_0586	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
A7A1_0587	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A7A1_0588	COG1695	Transcriptional regulator
A7A1_0589	COG0842	Transport permease protein
A7A1_0590	COG0842	Transport permease protein
A7A1_0590	COG1511	domain protein
A7A1_0591	COG1131	(ABC) transporter
A7A1_0592	COG2197	response regulator
A7A1_0593	COG4585	Histidine kinase
A7A1_0594	COG2514	catechol 2,3-dioxygenase activity
A7A1_0595	COG2259	Doxx family
A7A1_0596	COG1132	(ABC) transporter
A7A1_0597	COG1132	(ABC) transporter
A7A1_0598	COG1263	PTS System
A7A1_0598	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_0599	COG1737	Transcriptional regulator
A7A1_0600	COG1486	melibiose metabolic process
A7A1_0601	COG4842	Belongs to the WXG100 family
A7A1_0605	COG1742	UPF0060 membrane protein
A7A1_0607	COG3284	Transcriptional regulator
A7A1_0608	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7A1_0609	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7A1_0610	COG0022	dehydrogenase e1 component
A7A1_0611	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7A1_0613	COG4637	Psort location Cytoplasmic, score
A7A1_0614	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A7A1_0616	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7A1_0617	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A7A1_0618	COG0598	Magnesium transport protein CorA
A7A1_0619	COG2084	Dehydrogenase
A7A1_0620	COG0726	polysaccharide deacetylase
A7A1_0622	COG0535	radical SAM domain protein
A7A1_0623	COG0668	transmembrane transport
A7A1_0625	COG0387	Pfam Sodium calcium exchanger
A7A1_0626	COG0477	Major facilitator Superfamily
A7A1_0627	COG1295	ribonuclease BN
A7A1_0628	COG4980	gas vesicle protein
A7A1_0629	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7A1_0630	COG4840	Belongs to the UPF0435 family
A7A1_0631	COG2814	Major facilitator Superfamily
A7A1_0632	COG0693	protein deglycase activity
A7A1_0633	COG0737	Belongs to the 5'-nucleotidase family
A7A1_0634	COG0778	Nitroreductase
A7A1_0635	COG2188	Transcriptional regulator
A7A1_0636	COG0366	Alpha amylase catalytic
A7A1_0637	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_0637	COG1263	PTS System
A7A1_0638	COG0531	amino acid
A7A1_0639	COG1115	amino acid carrier protein
A7A1_0642	COG1368	sulfuric ester hydrolase activity
A7A1_0643	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_0643	COG1263	PTS System
A7A1_0644	COG0024	Methionine aminopeptidase
A7A1_0648	COG2258	MOSC domain
A7A1_0649	COG1254	Belongs to the acylphosphatase family
A7A1_0650	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A7A1_0651	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_0652	COG2851	Citrate transporter
A7A1_0653	COG3181	Tripartite tricarboxylate transporter family receptor
A7A1_0654	COG4565	transcriptional regulatory protein
A7A1_0655	COG3290	protein histidine kinase activity
A7A1_0656	COG0471	metal ion transport
A7A1_0657	COG3866	Pectate lyase
A7A1_0659	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7A1_0661	COG3832	glyoxalase III activity
A7A1_0663	COG0697	spore germination
A7A1_0664	COG0531	amino acid
A7A1_0670	COG4195	phage-related replication protein
A7A1_0672	COG0346	lactoylglutathione lyase activity
A7A1_0673	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7A1_0674	COG1388	LysM domain
A7A1_0675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A7A1_0676	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A7A1_0679	COG3763	UPF0154 protein
A7A1_0681	COG0785	Cytochrome C biogenesis protein
A7A1_0682	COG2201	protein-glutamate methylesterase activity
A7A1_0683	COG4846	Membrane protein involved in cytochrome C biogenesis
A7A1_0685	COG0071	Belongs to the small heat shock protein (HSP20) family
A7A1_0688	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A7A1_0689	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_0692	COG0824	Thioesterase
A7A1_0694	COG4841	protein insertion into membrane
A7A1_0695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A7A1_0696	COG1832	CoA-binding protein
A7A1_0697	COG0187	DNA topoisomerase II activity
A7A1_0698	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7A1_0700	COG1115	amino acid carrier protein
A7A1_0701	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
A7A1_0703	COG5520	Belongs to the glycosyl hydrolase 30 family
A7A1_0704	COG3507	Belongs to the glycosyl hydrolase 43 family
A7A1_0705	COG2246	polysaccharide biosynthetic process
A7A1_0706	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A7A1_0707	COG0586	Pfam SNARE associated Golgi protein
A7A1_0708	COG2404	hydrolase activity, acting on ester bonds
A7A1_0709	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7A1_0710	COG1024	Enoyl-CoA hydratase
A7A1_0711	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7A1_0712	COG0439	Biotin carboxylase
A7A1_0713	COG0318	PFAM AMP-dependent synthetase and ligase
A7A1_0714	COG1960	acyl-CoA dehydrogenase activity
A7A1_0716	COG1649	PFAM Uncharacterised BCR, COG1649
A7A1_0718	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A7A1_0718	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_0719	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
A7A1_0720	COG1114	Component of the transport system for branched-chain amino acids
A7A1_0721	COG1104	cysteine desulfurase activity
A7A1_0722	COG0301	tRNA thio-modification
A7A1_0724	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7A1_0725	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A7A1_0726	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7A1_0727	COG0616	signal peptide processing
A7A1_0728	COG1714	RDD family
A7A1_0730	COG3874	Sporulation protein YtfJ
A7A1_0731	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A7A1_0732	COG0827	DNA restriction-modification system
A7A1_0733	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A7A1_0734	COG0521	Mo-molybdopterin cofactor biosynthetic process
A7A1_0735	COG0137	argininosuccinate synthase activity
A7A1_0736	COG0165	Argininosuccinate lyase
A7A1_0738	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_0739	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7A1_0740	COG0583	DNA-binding transcription factor activity
A7A1_0741	COG0454	-acetyltransferase
A7A1_0742	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A1_0743	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A1_0744	COG0765	amino acid transport
A7A1_0745	COG0765	amino acid transport
A7A1_0746	COG1126	abc transporter atp-binding protein
A7A1_0747	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A1_0748	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A7A1_0749	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A1_0750	COG0196	riboflavin kinase activity
A7A1_0751	COG1473	amidohydrolase
A7A1_0752	COG0730	response to heat
A7A1_0753	COG4109	DRTGG domain
A7A1_0755	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A7A1_0758	COG0587	DNA-directed DNA polymerase activity
A7A1_0759	COG0587	DNA-directed DNA polymerase activity
A7A1_0760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A7A1_0761	COG0825	malonyl-CoA metabolic process
A7A1_0762	COG0205	6-phosphofructokinase activity
A7A1_0763	COG0469	pyruvate kinase activity
A7A1_0764	COG3030	protein affecting phage T7 exclusion by the F plasmid
A7A1_0765	COG0628	permease
A7A1_0766	COG2707	UPF0756 membrane protein
A7A1_0767	COG0372	Belongs to the citrate synthase family
A7A1_0768	COG0538	isocitrate dehydrogenase activity
A7A1_0769	COG0039	L-malate dehydrogenase activity
A7A1_0770	COG0745	RESPONSE REGULATOR receiver
A7A1_0771	COG5002	protein histidine kinase activity
A7A1_0772	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7A1_0772	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7A1_0773	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A7A1_0774	COG1971	Probably functions as a manganese efflux pump
A7A1_0775	COG0237	dephospho-CoA kinase activity
A7A1_0776	COG0656	L-ascorbic acid biosynthetic process
A7A1_0777	COG2814	Major facilitator Superfamily
A7A1_0778	COG1733	regulation of RNA biosynthetic process
A7A1_0779	COG0583	DNA-binding transcription factor activity
A7A1_0780	COG2851	Citrate transporter
A7A1_0781	COG0667	Aldo Keto reductase
A7A1_0782	COG1595	DNA-templated transcription, initiation
A7A1_0783	COG3443	Belongs to the bacterial solute-binding protein 9 family
A7A1_0785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A7A1_0786	COG2070	2-Nitropropane dioxygenase
A7A1_0788	COG2318	DinB family
A7A1_0791	COG1335	isochorismatase
A7A1_0793	COG2124	cytochrome p450
A7A1_0794	COG2732	(Barnase) inhibitor
A7A1_0795	COG1522	sequence-specific DNA binding
A7A1_0796	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A7A1_0797	COG1687	branched-chain amino acid
A7A1_0798	COG1114	Component of the transport system for branched-chain amino acids
A7A1_0800	COG0583	DNA-binding transcription factor activity
A7A1_0801	COG1942	4-Oxalocrotonate Tautomerase
A7A1_0802	COG1230	cation diffusion facilitator family transporter
A7A1_0803	COG2072	flavoprotein involved in K transport
A7A1_0804	COG0583	DNA-binding transcription factor activity
A7A1_0805	COG0697	spore germination
A7A1_0806	COG1253	flavin adenine dinucleotide binding
A7A1_0807	COG0456	acetyltransferase
A7A1_0808	COG2814	Major facilitator Superfamily
A7A1_0809	COG4978	Transcriptional regulator
A7A1_0809	COG0789	Transcriptional regulator
A7A1_0811	COG0662	Cupin 2, conserved barrel domain protein
A7A1_0814	COG2210	Belongs to the sulfur carrier protein TusA family
A7A1_0815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A1_0815	COG0425	Belongs to the sulfur carrier protein TusA family
A7A1_0817	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_0817	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A1_0818	COG0425	Belongs to the sulfur carrier protein TusA family
A7A1_0819	COG0730	response to heat
A7A1_0821	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7A1_0823	COG0454	-acetyltransferase
A7A1_0825	COG2311	Membrane
A7A1_0826	COG0745	RESPONSE REGULATOR receiver
A7A1_0827	COG5002	protein histidine kinase activity
A7A1_0827	COG0642	Histidine kinase
A7A1_0829	COG2856	Zn peptidase
A7A1_0830	COG0563	adenylate kinase activity
A7A1_0835	COG3677	Transposase
A7A1_0838	COG5484	DNA packaging
A7A1_0839	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A1_0839	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_0839	COG1388	LysM domain
A7A1_0841	COG1309	transcriptional regulator
A7A1_0844	COG5444	nuclease activity
A7A1_0848	COG0457	Tetratricopeptide repeat
A7A1_0850	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A7A1_0851	COG0477	Major facilitator Superfamily
A7A1_0854	COG3209	COG3209 Rhs family protein
A7A1_0856	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A7A1_0857	COG0398	Pfam SNARE associated Golgi protein
A7A1_0858	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A1_0858	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_0859	COG2755	lipolytic protein G-D-S-L family
A7A1_0861	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A7A1_0862	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A7A1_0863	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A7A1_0864	COG1534	Rna-binding protein
A7A1_0865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A7A1_0866	COG1713	HD superfamily hydrolase involved in NAD metabolism
A7A1_0867	COG0799	negative regulation of ribosome biogenesis
A7A1_0868	COG2226	methyltransferase
A7A1_0869	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7A1_0870	COG1555	photosystem II stabilization
A7A1_0870	COG1596	polysaccharide export
A7A1_0871	COG2131	deaminase
A7A1_0872	COG0658	competence protein
A7A1_0872	COG2333	competence protein COMEC
A7A1_0873	COG1466	dna polymerase III delta subunit
A7A1_0874	COG0268	Binds directly to 16S ribosomal RNA
A7A1_0875	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
A7A1_0876	COG2208	phosphoserine phosphatase activity
A7A1_0877	COG2304	oxidoreductase activity
A7A1_0878	COG0515	serine threonine protein kinase
A7A1_0879	COG0037	tRNA processing
A7A1_0881	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7A1_0882	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
A7A1_0883	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A7A1_0884	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7A1_0885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7A1_0886	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7A1_0887	COG0512	Glutamine amidotransferase of anthranilate synthase
A7A1_0888	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A1_0889	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A7A1_0890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A7A1_0891	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7A1_0892	COG1396	sequence-specific DNA binding
A7A1_0893	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A7A1_0894	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A7A1_0895	COG0367	asparagine synthase
A7A1_0896	COG2318	DinB family
A7A1_0897	COG1562	ergosterol biosynthetic process
A7A1_0898	COG0534	Mate efflux family protein
A7A1_0899	COG2207	Transcriptional regulator
A7A1_0899	COG1917	Cupin 2, conserved barrel domain protein
A7A1_0900	COG1609	Transcriptional regulator
A7A1_0901	COG0673	inositol 2-dehydrogenase activity
A7A1_0902	COG2318	DinB family
A7A1_0903	COG1279	arginine transmembrane transporter activity
A7A1_0904	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A1_0905	COG1357	PFAM Pentapeptide repeats (8 copies)
A7A1_0906	COG2267	carboxylic ester hydrolase activity
A7A1_0907	COG0529	Catalyzes the synthesis of activated sulfate
A7A1_0908	COG2046	Belongs to the sulfate adenylyltransferase family
A7A1_0909	COG0175	sulfate reduction
A7A1_0910	COG2045	Belongs to the ComB family
A7A1_0911	COG1809	phosphosulfolactate synthase activity
A7A1_0912	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A1_0913	COG4948	Mandelate Racemase Muconate Lactonizing
A7A1_0914	COG2814	Major facilitator Superfamily
A7A1_0915	COG0454	-acetyltransferase
A7A1_0916	COG2153	protein acetylation
A7A1_0917	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A7A1_0917	COG0646	methionine synthase
A7A1_0918	COG1666	GTP binding
A7A1_0919	COG2996	Protein conserved in bacteria
A7A1_0923	COG1695	Transcriptional regulator
A7A1_0926	COG3227	Zinc metalloprotease (Elastase)
A7A1_0927	COG1307	EDD domain protein, DegV family
A7A1_0928	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A1_0930	COG0561	phosphatase activity
A7A1_0931	COG1073	alpha beta
A7A1_0932	COG2151	metal-sulfur cluster biosynthetic enzyme
A7A1_0933	COG0277	FAD linked oxidase domain protein
A7A1_0934	COG2271	Major facilitator Superfamily
A7A1_0935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A7A1_0939	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7A1_0940	COG0505	Belongs to the CarA family
A7A1_0941	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A7A1_0942	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A7A1_0945	COG2267	carboxylic ester hydrolase activity
A7A1_0947	COG1744	ABC transporter substrate-binding protein PnrA-like
A7A1_0950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A1_0951	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7A1_0952	COG5504	Zn-dependent protease
A7A1_0953	COG0444	Belongs to the ABC transporter superfamily
A7A1_0954	COG4608	Belongs to the ABC transporter superfamily
A7A1_0956	COG0601	transmembrane transport
A7A1_0957	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7A1_0959	COG0180	Tryptophanyl-tRNA synthetase
A7A1_0960	COG4166	transmembrane transport
A7A1_0961	COG0601	transmembrane transport
A7A1_0962	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7A1_0963	COG0444	Belongs to the ABC transporter superfamily
A7A1_0964	COG4608	Belongs to the ABC transporter superfamily
A7A1_0965	COG2814	Major facilitator Superfamily
A7A1_0966	COG0456	acetyltransferase
A7A1_0967	COG1393	Belongs to the ArsC family
A7A1_0968	COG0861	Integral membrane protein TerC family
A7A1_0969	COG4862	establishment of competence for transformation
A7A1_0970	COG4469	Competence protein
A7A1_0971	COG1164	Oligoendopeptidase f
A7A1_0973	COG2346	COG2346, Truncated hemoglobins
A7A1_0974	COG0741	lytic transglycosylase activity
A7A1_0975	COG4116	CYTH
A7A1_0977	COG2357	RelA SpoT domain protein
A7A1_0978	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7A1_0979	COG0564	pseudouridine synthase activity
A7A1_0980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A7A1_0981	COG0475	glutathione-regulated potassium exporter activity
A7A1_0981	COG0569	domain protein
A7A1_0982	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A7A1_0983	COG0352	thiamine-phosphate diphosphorylase activity
A7A1_0984	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7A1_0985	COG2104	thiamine diphosphate biosynthetic process
A7A1_0986	COG2022	thiamine diphosphate biosynthetic process
A7A1_0987	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7A1_0988	COG0351	phosphomethylpyrimidine kinase
A7A1_0989	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A7A1_1000	COG0210	DNA helicase
A7A1_1002	COG2153	protein acetylation
A7A1_1003	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A7A1_1004	COG2382	esterase
A7A1_1007	COG0679	Auxin Efflux Carrier
A7A1_1008	COG0789	Transcriptional regulator
A7A1_1009	COG0346	lactoylglutathione lyase activity
A7A1_1010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A7A1_1011	COG2890	protein-(glutamine-N5) methyltransferase activity
A7A1_1015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A7A1_1016	COG0009	L-threonylcarbamoyladenylate synthase
A7A1_1017	COG1971	Probably functions as a manganese efflux pump
A7A1_1018	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7A1_1019	COG0698	ribose 5-phosphate isomerase
A7A1_1020	COG4475	Protein of unknown function (DUF436)
A7A1_1021	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7A1_1022	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A7A1_1024	COG0356	it plays a direct role in the translocation of protons across the membrane
A7A1_1025	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A7A1_1026	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A7A1_1027	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A7A1_1028	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A7A1_1029	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A7A1_1030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A7A1_1031	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A7A1_1033	COG4836	Membrane
A7A1_1035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A7A1_1036	COG2385	sporulation resulting in formation of a cellular spore
A7A1_1037	COG2304	oxidoreductase activity
A7A1_1039	COG2304	oxidoreductase activity
A7A1_1041	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A7A1_1042	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7A1_1043	COG0457	Tetratricopeptide repeat
A7A1_1044	COG1994	Peptidase M50
A7A1_1045	COG3237	CsbD-like
A7A1_1047	COG0831	urea catabolic process
A7A1_1048	COG0832	Belongs to the urease beta subunit family
A7A1_1049	COG0804	urea catabolic process
A7A1_1050	COG1959	2 iron, 2 sulfur cluster binding
A7A1_1051	COG2910	NAD(P)H-binding
A7A1_1053	COG0789	Transcriptional regulator
A7A1_1054	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7A1_1057	COG1247	-acetyltransferase
A7A1_1058	COG0739	heme binding
A7A1_1062	COG0671	phosphoesterase, PA-phosphatase related
A7A1_1063	COG0347	Belongs to the P(II) protein family
A7A1_1064	COG0004	ammonium transporteR
A7A1_1066	COG1335	isochorismatase
A7A1_1067	COG0477	Major facilitator Superfamily
A7A1_1068	COG1953	Uracil, thiamine, allantoin
A7A1_1069	COG3420	alginic acid biosynthetic process
A7A1_1070	COG2814	Major facilitator Superfamily
A7A1_1071	COG1846	Transcriptional regulator
A7A1_1073	COG1609	Transcriptional regulator
A7A1_1074	COG1077	Cell shape determining protein MreB Mrl
A7A1_1075	COG4786	Flagellar basal body rod
A7A1_1076	COG4786	Flagellar basal body rod
A7A1_1077	COG0457	Tetratricopeptide repeat
A7A1_1078	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A7A1_1079	COG1970	mechanosensitive ion channel activity
A7A1_1080	COG2972	Histidine kinase
A7A1_1080	COG0745	RESPONSE REGULATOR receiver
A7A1_1081	COG3279	Response regulator of the LytR AlgR family
A7A1_1084	COG3764	Sortase (surface protein transpeptidase)
A7A1_1087	COG0629	single-stranded DNA binding
A7A1_1088	COG1349	DNA-binding transcription factor activity
A7A1_1089	COG0561	phosphatase activity
A7A1_1090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7A1_1091	COG4715	Zinc finger, swim domain protein
A7A1_1092	COG3944	biosynthesis protein
A7A1_1093	COG0489	protein tyrosine kinase activity
A7A1_1094	COG4464	protein tyrosine phosphatase activity
A7A1_1095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7A1_1096	COG3878	Protein conserved in bacteria
A7A1_1101	COG0583	DNA-binding transcription factor activity
A7A1_1102	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7A1_1104	COG2059	Chromate
A7A1_1105	COG2059	Chromate
A7A1_1106	COG1522	sequence-specific DNA binding
A7A1_1107	COG0405	Gamma-glutamyltransferase
A7A1_1109	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7A1_1111	COG5337	Spore coat protein CotH
A7A1_1114	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7A1_1115	COG0583	DNA-binding transcription factor activity
A7A1_1116	COG0028	Belongs to the TPP enzyme family
A7A1_1117	COG3527	Alpha-acetolactate decarboxylase
A7A1_1118	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7A1_1120	COG3103	Sh3 type 3 domain protein
A7A1_1121	COG1879	ABC-type sugar transport system periplasmic component
A7A1_1122	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7A1_1123	COG1129	ABC transporter
A7A1_1124	COG1869	D-ribose catabolic process
A7A1_1125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7A1_1126	COG1609	Transcriptional regulator
A7A1_1127	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A7A1_1129	COG2843	Capsule synthesis protein
A7A1_1131	COG0791	NLP P60 protein
A7A1_1132	COG0561	phosphatase activity
A7A1_1133	COG1316	TRANSCRIPTIONal
A7A1_1134	COG2814	Major facilitator Superfamily
A7A1_1136	COG0814	amino acid
A7A1_1137	COG0697	spore germination
A7A1_1138	COG1482	cell wall glycoprotein biosynthetic process
A7A1_1139	COG4193	domain, Protein
A7A1_1148	COG0463	Glycosyl transferase, family 2
A7A1_1149	COG1215	transferase activity, transferring glycosyl groups
A7A1_1149	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7A1_1150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7A1_1150	COG1215	transferase activity, transferring glycosyl groups
A7A1_1151	COG1215	transferase activity, transferring glycosyl groups
A7A1_1151	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7A1_1152	COG1682	transport, permease protein
A7A1_1153	COG1134	teichoic acid transport
A7A1_1154	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A7A1_1159	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7A1_1160	COG1316	TRANSCRIPTIONal
A7A1_1162	COG2385	sporulation resulting in formation of a cellular spore
A7A1_1162	COG2247	cell wall binding repeat
A7A1_1163	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A1_1163	COG2247	cell wall binding repeat
A7A1_1166	COG2244	polysaccharide biosynthetic process
A7A1_1167	COG0297	glycogen (starch) synthase activity
A7A1_1167	COG0438	transferase activity, transferring glycosyl groups
A7A1_1168	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7A1_1169	COG3307	-O-antigen
A7A1_1170	COG3206	protein involved in exopolysaccharide biosynthesis
A7A1_1171	COG5444	nuclease activity
A7A1_1172	COG0438	transferase activity, transferring glycosyl groups
A7A1_1173	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7A1_1174	COG1316	TRANSCRIPTIONal
A7A1_1175	COG1739	Uncharacterized protein family UPF0029
A7A1_1176	COG4585	Histidine kinase
A7A1_1177	COG2197	response regulator
A7A1_1178	COG1307	EDD domain protein, DegV family
A7A1_1179	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A7A1_1181	COG1040	competence protein
A7A1_1183	COG2747	anti-sigma28 factor FlgM
A7A1_1184	COG3418	PFAM FlgN family protein
A7A1_1185	COG1256	bacterial-type flagellum assembly
A7A1_1185	COG4786	Flagellar basal body rod
A7A1_1186	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7A1_1188	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
A7A1_1189	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A7A1_1190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7A1_1191	COG1334	flagellar protein FlaG
A7A1_1192	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A7A1_1193	COG1516	flagellar protein fliS
A7A1_1196	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A7A1_1197	COG0653	protein targeting
A7A1_1198	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A7A1_1199	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A1_1200	COG2010	Cytochrome c
A7A1_1201	COG2884	Cell division ATP-binding protein ftsE
A7A1_1202	COG2177	Part of the ABC transporter FtsEX involved in
A7A1_1203	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_1203	COG0793	Belongs to the peptidase S41A family
A7A1_1205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7A1_1206	COG2814	Major facilitator Superfamily
A7A1_1207	COG1309	transcriptional regulator
A7A1_1208	COG0574	Belongs to the PEP-utilizing enzyme family
A7A1_1208	COG3848	Pyruvate phosphate dikinase
A7A1_1209	COG0556	nucleotide-excision repair
A7A1_1210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7A1_1211	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7A1_1214	COG3595	metallopeptidase activity
A7A1_1215	COG1983	PspC domain protein
A7A1_1216	COG1950	PFAM Membrane protein of
A7A1_1217	COG2814	Major facilitator Superfamily
A7A1_1218	COG1846	Transcriptional regulator
A7A1_1220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_1221	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_1222	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_1224	COG0517	IMP dehydrogenase activity
A7A1_1224	COG0516	GMP reductase activity
A7A1_1225	COG1686	Belongs to the peptidase S11 family
A7A1_1226	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A7A1_1227	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A7A1_1228	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A7A1_1229	COG1428	Deoxynucleoside kinase
A7A1_1230	COG1428	Deoxynucleoside kinase
A7A1_1231	COG1388	LysM domain
A7A1_1231	COG3858	chitin binding
A7A1_1232	COG1335	isochorismatase
A7A1_1233	COG0590	tRNA wobble adenosine to inosine editing
A7A1_1234	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7A1_1235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A7A1_1236	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A7A1_1240	COG0346	lactoylglutathione lyase activity
A7A1_1241	COG0305	Participates in initiation and elongation during chromosome replication
A7A1_1244	COG3093	addiction module antidote protein HigA
A7A1_1245	COG2807	transmembrane transport
A7A1_1246	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A7A1_1247	COG0359	binds to the 23S rRNA
A7A1_1248	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7A1_1249	COG4241	membrane
A7A1_1250	COG5577	PFAM Coat F domain
A7A1_1251	COG1733	regulation of RNA biosynthetic process
A7A1_1252	COG1227	inorganic diphosphatase activity
A7A1_1255	COG2271	Major facilitator Superfamily
A7A1_1256	COG4978	Transcriptional regulator
A7A1_1256	COG0789	Transcriptional regulator
A7A1_1258	COG4319	ketosteroid isomerase
A7A1_1259	COG1357	PFAM Pentapeptide repeats (8 copies)
A7A1_1260	COG2814	Major facilitator Superfamily
A7A1_1261	COG0583	DNA-binding transcription factor activity
A7A1_1262	COG2153	protein acetylation
A7A1_1263	COG2814	Major facilitator Superfamily
A7A1_1266	COG0789	Transcriptional regulator
A7A1_1267	COG0697	spore germination
A7A1_1268	COG1331	Highly conserved protein containing a thioredoxin domain
A7A1_1269	COG1266	CAAX protease self-immunity
A7A1_1270	COG0477	Major facilitator Superfamily
A7A1_1270	COG2814	Major facilitator Superfamily
A7A1_1271	COG0110	maltose O-acetyltransferase activity
A7A1_1272	COG0346	lactoylglutathione lyase activity
A7A1_1273	COG1609	Transcriptional regulator
A7A1_1274	COG0708	Exodeoxyribonuclease III
A7A1_1275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A7A1_1276	COG0629	single-stranded DNA binding
A7A1_1277	COG0360	Binds together with S18 to 16S ribosomal RNA
A7A1_1278	COG0012	GTP binding
A7A1_1279	COG1475	DNA binding
A7A1_1280	COG1192	Involved in chromosome partitioning
A7A1_1282	COG1475	DNA binding
A7A1_1283	COG0357	Ribosomal RNA small subunit methyltransferase G
A7A1_1284	COG0445	tRNA wobble uridine modification
A7A1_1285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A7A1_1286	COG1847	R3H domain protein
A7A1_1287	COG0706	membrane insertase activity
A7A1_1288	COG0594	ribonuclease P activity
A7A1_1289	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A7A1_1290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A7A1_1291	COG0592	DNA-directed DNA polymerase activity
A7A1_1292	COG2501	S4 domain
A7A1_1293	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A7A1_1295	COG0187	DNA topoisomerase II activity
A7A1_1296	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7A1_1297	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7A1_1298	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7A1_1299	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_1301	COG5444	nuclease activity
A7A1_1307	COG1476	TRANSCRIPTIONal
A7A1_1310	COG0693	protein deglycase activity
A7A1_1311	COG1278	Cold shock
A7A1_1312	COG1329	Transcriptional regulator
A7A1_1313	COG0697	spore germination
A7A1_1314	COG2207	Transcriptional regulator
A7A1_1314	COG1917	Cupin 2, conserved barrel domain protein
A7A1_1315	COG0697	spore germination
A7A1_1316	COG2207	Transcriptional regulator
A7A1_1316	COG3708	Transcriptional regulator
A7A1_1317	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A1_1318	COG0477	Major facilitator Superfamily
A7A1_1320	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
A7A1_1323	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A1_1324	COG1309	transcriptional regulator
A7A1_1325	COG0697	spore germination
A7A1_1326	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A1_1327	COG2030	dehydratase
A7A1_1328	COG3545	Serine hydrolase
A7A1_1329	COG1733	regulation of RNA biosynthetic process
A7A1_1330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A1_1331	COG1733	regulation of RNA biosynthetic process
A7A1_1332	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7A1_1333	COG2814	Major facilitator Superfamily
A7A1_1334	COG1309	transcriptional regulator
A7A1_1335	COG0640	Transcriptional regulator
A7A1_1336	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7A1_1337	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_1338	COG0697	spore germination
A7A1_1339	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A1_1340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7A1_1341	COG0640	Transcriptional regulator
A7A1_1342	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7A1_1343	COG4585	Histidine kinase
A7A1_1344	COG2197	response regulator
A7A1_1345	COG2409	Drug exporters of the RND superfamily
A7A1_1346	COG0596	Alpha beta hydrolase
A7A1_1347	COG1811	Na channel or pump
A7A1_1348	COG4978	Transcriptional regulator
A7A1_1348	COG0789	Transcriptional regulator
A7A1_1349	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7A1_1350	COG0778	Nitroreductase
A7A1_1351	COG0346	lactoylglutathione lyase activity
A7A1_1352	COG2259	Doxx family
A7A1_1353	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_1356	COG2323	membrane
A7A1_1357	COG2323	membrane
A7A1_1358	COG0071	Belongs to the small heat shock protein (HSP20) family
A7A1_1361	COG1309	transcriptional regulator
A7A1_1363	COG0456	acetyltransferase
A7A1_1365	COG1113	amino acid transport
A7A1_1366	COG2318	DinB family
A7A1_1367	COG1846	Transcriptional regulator
A7A1_1368	COG2409	Drug exporters of the RND superfamily
A7A1_1368	COG1033	growth of symbiont in host cell
A7A1_1369	COG2409	Drug exporters of the RND superfamily
A7A1_1369	COG1033	growth of symbiont in host cell
A7A1_1370	COG0778	Nitroreductase
A7A1_1371	COG1846	Transcriptional regulator
A7A1_1372	COG2814	Major facilitator Superfamily
A7A1_1373	COG0730	response to heat
A7A1_1374	COG1802	Transcriptional regulator
A7A1_1375	COG1388	LysM domain
A7A1_1375	COG3858	chitin binding
A7A1_1376	COG1819	glycosyl
A7A1_1378	COG1785	Belongs to the alkaline phosphatase family
A7A1_1379	COG5646	InterPro IPR014922
A7A1_1381	COG0454	-acetyltransferase
A7A1_1382	COG1078	dGTPase activity
A7A1_1383	COG1388	LysM domain
A7A1_1384	COG2814	Major facilitator Superfamily
A7A1_1385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A1_1386	COG1447	Phosphotransferase system cellobiose-specific component IIA
A7A1_1387	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A1_1388	COG2723	6-phospho-beta-galactosidase activity
A7A1_1389	COG2188	Transcriptional regulator
A7A1_1390	COG1940	carbohydrate kinase activity
A7A1_1391	COG1482	cell wall glycoprotein biosynthetic process
A7A1_1392	COG4124	Belongs to the glycosyl hydrolase 26 family
A7A1_1394	COG0705	Rhomboid family
A7A1_1395	COG0736	holo-[acyl-carrier-protein] synthase activity
A7A1_1396	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A7A1_1397	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A7A1_1398	COG0864	Transcriptional regulator
A7A1_1399	COG2337	Toxic component of a toxin-antitoxin (TA) module
A7A1_1400	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_1401	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_1402	COG2172	sigma factor antagonist activity
A7A1_1403	COG2208	phosphoserine phosphatase activity
A7A1_1404	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_1405	COG2172	sigma factor antagonist activity
A7A1_1406	COG1191	sigma factor activity
A7A1_1407	COG2208	phosphoserine phosphatase activity
A7A1_1408	COG2183	response to ionizing radiation
A7A1_1409	COG3091	SprT-like family
A7A1_1410	COG3953	SLT domain
A7A1_1410	COG5412	phage tail tape measure protein
A7A1_1411	COG1652	LysM domain
A7A1_1412	COG4193	domain, Protein
A7A1_1414	COG3628	GPW Gp25 family protein
A7A1_1415	COG3299	homolog of phage Mu protein gp47
A7A1_1416	COG3778	Protein conserved in bacteria
A7A1_1424	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_1424	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A1_1427	COG0306	phosphate transporter
A7A1_1428	COG1392	Phosphate transport regulator
A7A1_1429	COG0531	amino acid
A7A1_1430	COG0346	lactoylglutathione lyase activity
A7A1_1431	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A7A1_1432	COG0463	Glycosyl transferase, family 2
A7A1_1434	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7A1_1435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7A1_1436	COG2362	D-Aminopeptidase
A7A1_1437	COG0601	transmembrane transport
A7A1_1438	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7A1_1439	COG0444	Belongs to the ABC transporter superfamily
A7A1_1440	COG4166	transmembrane transport
A7A1_1441	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7A1_1442	COG4948	Mandelate Racemase Muconate Lactonizing
A7A1_1443	COG0791	NLP P60 protein
A7A1_1444	COG4608	Belongs to the ABC transporter superfamily
A7A1_1445	COG2706	6-phosphogluconolactonase activity
A7A1_1446	COG1834	amidinotransferase
A7A1_1447	COG1607	acyl-coa hydrolase
A7A1_1448	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A7A1_1448	COG1017	nitric oxide dioxygenase activity
A7A1_1450	COG2323	membrane
A7A1_1451	COG2318	DinB family
A7A1_1452	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_1453	COG2076	Multidrug Resistance protein
A7A1_1454	COG2076	Multidrug Resistance protein
A7A1_1455	COG0788	formyltetrahydrofolate deformylase activity
A7A1_1456	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A7A1_1457	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A7A1_1458	COG1764	response to oxidative stress
A7A1_1459	COG1846	Transcriptional regulator
A7A1_1460	COG1764	response to oxidative stress
A7A1_1461	COG0590	tRNA wobble adenosine to inosine editing
A7A1_1462	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A7A1_1463	COG1404	Belongs to the peptidase S8 family
A7A1_1464	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_1465	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7A1_1466	COG1122	ATPase activity
A7A1_1467	COG4721	ABC-type cobalt transport system, permease component
A7A1_1469	COG0745	RESPONSE REGULATOR receiver
A7A1_1470	COG5002	protein histidine kinase activity
A7A1_1470	COG3850	Histidine kinase
A7A1_1471	COG3212	peptidase
A7A1_1472	COG3212	peptidase
A7A1_1474	COG2239	Acts as a magnesium transporter
A7A1_1475	COG0789	Transcriptional regulator
A7A1_1478	COG1846	Transcriptional regulator
A7A1_1479	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A7A1_1480	COG0726	polysaccharide deacetylase
A7A1_1481	COG1408	metallophosphoesterase
A7A1_1483	COG0463	Glycosyl transferase, family 2
A7A1_1484	COG1793	dna ligase
A7A1_1484	COG3285	dna ligase
A7A1_1485	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A7A1_1486	COG5001	Diguanylate cyclase
A7A1_1486	COG3300	MHYT domain
A7A1_1487	COG0586	Pfam SNARE associated Golgi protein
A7A1_1488	COG0861	Integral membrane protein TerC family
A7A1_1489	COG1191	sigma factor activity
A7A1_1493	COG0501	Belongs to the peptidase M48B family
A7A1_1494	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7A1_1496	COG3594	Acyltransferase
A7A1_1497	COG5002	protein histidine kinase activity
A7A1_1498	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7A1_1499	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7A1_1500	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
A7A1_1501	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7A1_1502	COG0436	Aminotransferase
A7A1_1503	COG1850	ribulose-bisphosphate carboxylase activity
A7A1_1504	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
A7A1_1505	COG0235	Class ii aldolase
A7A1_1506	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
A7A1_1507	COG3339	Conserved Protein
A7A1_1510	COG3852	Histidine kinase
A7A1_1511	COG1846	Transcriptional regulator
A7A1_1512	COG1360	Flagellar Motor Protein
A7A1_1513	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A7A1_1514	COG0542	response to heat
A7A1_1515	COG3949	Membrane
A7A1_1516	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A7A1_1517	COG0720	synthase
A7A1_1518	COG0602	queuosine metabolic process
A7A1_1519	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A7A1_1520	COG1733	regulation of RNA biosynthetic process
A7A1_1521	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_1523	COG4641	Protein conserved in bacteria
A7A1_1523	COG1388	LysM domain
A7A1_1524	COG3858	chitin binding
A7A1_1526	COG4873	Protein conserved in bacteria
A7A1_1527	COG3773	Cell wall hydrolase
A7A1_1529	COG2244	polysaccharide biosynthetic process
A7A1_1530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_1531	COG2217	Heavy metal translocating P-type atpase
A7A1_1532	COG0006	proline dipeptidase activity
A7A1_1533	COG1609	Transcriptional regulator
A7A1_1534	COG3711	transcriptional antiterminator
A7A1_1535	COG2190	(PTS) system
A7A1_1535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_1535	COG1263	PTS System
A7A1_1536	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7A1_1539	COG1533	DNA photolyase activity
A7A1_1540	COG0456	acetyltransferase
A7A1_1541	COG0840	transmembrane signaling receptor activity
A7A1_1542	COG2084	Dehydrogenase
A7A1_1543	COG2340	Cysteine-rich secretory protein family
A7A1_1544	COG0768	penicillin binding
A7A1_1545	COG4191	Histidine kinase
A7A1_1546	COG0436	Aminotransferase
A7A1_1547	COG0835	chemotaxis
A7A1_1547	COG0784	Response regulator, receiver
A7A1_1549	COG2814	Major facilitator Superfamily
A7A1_1550	COG1376	ErfK ybiS ycfS ynhG family protein
A7A1_1551	COG1408	metallophosphoesterase
A7A1_1552	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_1553	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_1555	COG2200	EAL domain
A7A1_1556	COG4703	Protein of unknown function (DUF1797)
A7A1_1557	COG0659	secondary active sulfate transmembrane transporter activity
A7A1_1558	COG0385	Bile acid
A7A1_1559	COG2819	hydrolase of the alpha beta superfamily
A7A1_1560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_1561	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_1562	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A1_1563	COG2207	Transcriptional regulator
A7A1_1563	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A1_1564	COG3876	Protein conserved in bacteria
A7A1_1565	COG1472	Belongs to the glycosyl hydrolase 3 family
A7A1_1566	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7A1_1567	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_1567	COG1263	PTS System
A7A1_1568	COG1737	Transcriptional regulator
A7A1_1569	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A7A1_1570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_1571	COG1683	Conserved Protein
A7A1_1572	COG0322	excinuclease ABC activity
A7A1_1574	COG0527	aspartate kinase activity
A7A1_1575	COG1719	4-vinyl reductase, 4VR
A7A1_1576	COG2009	succinate dehydrogenase
A7A1_1577	COG1053	succinate dehydrogenase
A7A1_1578	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A7A1_1579	COG0824	Thioesterase
A7A1_1580	COG2197	response regulator
A7A1_1581	COG1846	Transcriptional regulator
A7A1_1582	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A7A1_1583	COG5401	PFAM Sporulation and spore germination
A7A1_1584	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A7A1_1585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A7A1_1586	COG0622	Phosphoesterase
A7A1_1587	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
A7A1_1588	COG0454	-acetyltransferase
A7A1_1590	COG0028	Belongs to the TPP enzyme family
A7A1_1591	COG0440	acetolactate synthase activity
A7A1_1592	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A7A1_1593	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7A1_1594	COG0473	3-isopropylmalate dehydrogenase activity
A7A1_1595	COG3428	Bacterial PH domain
A7A1_1596	COG3402	PFAM membrane-flanked domain
A7A1_1597	COG0513	Belongs to the DEAD box helicase family
A7A1_1598	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7A1_1599	COG1181	Belongs to the D-alanine--D-alanine ligase family
A7A1_1600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_1601	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7A1_1603	COG1960	acyl-CoA dehydrogenase activity
A7A1_1605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A7A1_1606	COG1131	(ABC) transporter
A7A1_1607	COG0628	permease
A7A1_1608	COG1301	dicarboxylic acid transport
A7A1_1609	COG4565	transcriptional regulatory protein
A7A1_1610	COG3290	protein histidine kinase activity
A7A1_1611	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A7A1_1612	COG3546	catalase activity
A7A1_1613	COG2329	Antibiotic biosynthesis monooxygenase
A7A1_1614	COG0662	Cupin 2, conserved barrel domain protein
A7A1_1615	COG3729	General stress protein
A7A1_1616	COG2217	Heavy metal translocating P-type atpase
A7A1_1617	COG4876	unkown
A7A1_1618	COG2261	transglycosylase associated protein
A7A1_1619	COG1914	H( )-stimulated, divalent metal cation uptake system
A7A1_1621	COG0028	Belongs to the TPP enzyme family
A7A1_1622	COG0494	nUDIX hydrolase
A7A1_1623	COG0531	amino acid
A7A1_1625	COG1215	transferase activity, transferring glycosyl groups
A7A1_1626	COG5298	Protein conserved in bacteria
A7A1_1627	COG3706	GGDEF domain
A7A1_1628	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A7A1_1629	COG0551	DNA topoisomerase type I activity
A7A1_1629	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7A1_1630	COG1522	sequence-specific DNA binding
A7A1_1631	COG2814	Major facilitator Superfamily
A7A1_1633	COG3871	stress protein (general stress protein 26)
A7A1_1634	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_1635	COG1917	Cupin 2, conserved barrel domain protein
A7A1_1636	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_1637	COG2226	methyltransferase
A7A1_1638	COG0318	PFAM AMP-dependent synthetase and ligase
A7A1_1639	COG3711	transcriptional antiterminator
A7A1_1640	COG4989	oxidoreductase activity
A7A1_1641	COG0768	penicillin binding
A7A1_1642	COG2202	Pas domain
A7A1_1642	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_1644	COG0495	leucyl-tRNA aminoacylation
A7A1_1645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A1_1646	COG1486	melibiose metabolic process
A7A1_1651	COG1073	alpha beta
A7A1_1652	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
A7A1_1653	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7A1_1654	COG0156	8-amino-7-oxononanoate synthase activity
A7A1_1656	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A7A1_1657	COG2124	cytochrome p450
A7A1_1658	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A1_1659	COG0395	ABC-type sugar transport system, permease component
A7A1_1660	COG1653	transport
A7A1_1661	COG2207	Transcriptional regulator
A7A1_1662	COG4209	transmembrane transport
A7A1_1663	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A7A1_1664	COG1653	transport
A7A1_1665	COG0673	inositol 2-dehydrogenase activity
A7A1_1666	COG5578	integral membrane protein
A7A1_1668	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7A1_1669	COG2081	HI0933 family
A7A1_1670	COG2244	polysaccharide biosynthetic process
A7A1_1671	COG1187	pseudouridine synthase activity
A7A1_1672	COG1187	pseudouridine synthase activity
A7A1_1673	COG1349	DNA-binding transcription factor activity
A7A1_1674	COG1131	(ABC) transporter
A7A1_1675	COG4473	ABC transporter
A7A1_1676	COG2252	PERMEase
A7A1_1677	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7A1_1678	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7A1_1679	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A7A1_1681	COG1597	lipid kinase activity
A7A1_1682	COG1523	belongs to the glycosyl hydrolase 13 family
A7A1_1683	COG0510	thiamine kinase activity
A7A1_1685	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A7A1_1686	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_1687	COG0281	malic enzyme
A7A1_1688	COG5584	Small secreted protein
A7A1_1689	COG1363	Peptidase, m42
A7A1_1691	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_1692	COG4848	Belongs to the UPF0354 family
A7A1_1693	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7A1_1694	COG1674	ftsk spoiiie
A7A1_1695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A7A1_1696	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A7A1_1697	COG4980	gas vesicle protein
A7A1_1698	COG3118	belongs to the thioredoxin family
A7A1_1699	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A7A1_1699	COG1605	Chorismate mutase
A7A1_1700	COG1609	Transcriptional regulator
A7A1_1701	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A7A1_1702	COG1360	Flagellar Motor Protein
A7A1_1703	COG0123	including yeast histone deacetylase and acetoin utilization protein
A7A1_1704	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7A1_1705	COG0454	-acetyltransferase
A7A1_1706	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A7A1_1707	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A7A1_1708	COG2199	diguanylate cyclase activity
A7A1_1708	COG2203	Gaf domain
A7A1_1709	COG1956	GAF domain-containing protein
A7A1_1710	COG1309	transcriptional regulator
A7A1_1711	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7A1_1712	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_1713	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_1715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7A1_1716	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A7A1_1718	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A7A1_1722	COG5444	nuclease activity
A7A1_1723	COG3391	amine dehydrogenase activity
A7A1_1727	COG0457	Tetratricopeptide repeat
A7A1_1728	COG0217	transcriptional regulatory protein
A7A1_1730	COG1309	transcriptional regulator
A7A1_1731	COG3631	Ketosteroid isomerase-related protein
A7A1_1732	COG0702	epimerase
A7A1_1735	COG3546	catalase activity
A7A1_1736	COG0454	-acetyltransferase
A7A1_1738	COG5578	integral membrane protein
A7A1_1739	COG2972	Histidine kinase
A7A1_1740	COG2207	Transcriptional regulator
A7A1_1740	COG4753	response regulator
A7A1_1741	COG1653	transport
A7A1_1742	COG1175	transmembrane transport
A7A1_1743	COG0395	ABC-type sugar transport system, permease component
A7A1_1744	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A7A1_1745	COG2207	Transcriptional regulator
A7A1_1746	COG2755	lipolytic protein G-D-S-L family
A7A1_1748	COG5578	integral membrane protein
A7A1_1749	COG3401	FG-GAP repeat protein
A7A1_1750	COG3401	FG-GAP repeat protein
A7A1_1751	COG2755	lipolytic protein G-D-S-L family
A7A1_1752	COG1874	Beta-galactosidase
A7A1_1754	COG1653	transport
A7A1_1755	COG4209	transmembrane transport
A7A1_1756	COG0395	ABC-type sugar transport system, permease component
A7A1_1757	COG1486	melibiose metabolic process
A7A1_1758	COG2323	membrane
A7A1_1759	COG2329	Antibiotic biosynthesis monooxygenase
A7A1_1760	COG0346	lactoylglutathione lyase activity
A7A1_1763	COG5583	Uncharacterized small protein (DUF2292)
A7A1_1764	COG0670	Belongs to the BI1 family
A7A1_1765	COG1846	Transcriptional regulator
A7A1_1766	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7A1_1768	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A7A1_1768	COG2124	cytochrome p450
A7A1_1769	COG1368	sulfuric ester hydrolase activity
A7A1_1770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7A1_1771	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A1_1772	COG1442	glycosyl transferase family 8
A7A1_1773	COG1216	Glycosyl transferase, family 2
A7A1_1774	COG1442	glycosyl transferase family 8
A7A1_1775	COG2223	nitrite transmembrane transporter activity
A7A1_1776	COG1011	Hydrolase
A7A1_1777	COG0531	amino acid
A7A1_1778	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_1779	COG0840	transmembrane signaling receptor activity
A7A1_1780	COG0488	(ABC) transporter
A7A1_1782	COG0789	Transcriptional regulator
A7A1_1783	COG2814	Major facilitator Superfamily
A7A1_1785	COG0488	(ABC) transporter
A7A1_1786	COG0513	Belongs to the DEAD box helicase family
A7A1_1787	COG0456	acetyltransferase
A7A1_1788	COG2130	NADP-dependent
A7A1_1789	COG2211	Major facilitator Superfamily
A7A1_1791	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A7A1_1792	COG1120	ATPase activity
A7A1_1793	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_1794	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_1795	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7A1_1799	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
A7A1_1800	COG3853	Toxic anion resistance protein (TelA)
A7A1_1801	COG1982	Orn Lys Arg decarboxylase major
A7A1_1802	COG1982	Orn Lys Arg decarboxylase major
A7A1_1803	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A7A1_1804	COG3870	Protein conserved in bacteria
A7A1_1805	COG1728	Protein conserved in bacteria
A7A1_1806	COG0470	DNA polymerase III
A7A1_1807	COG1774	PSP1 C-terminal conserved region
A7A1_1808	COG4467	Involved in initiation control of chromosome replication
A7A1_1809	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A7A1_1810	COG2827	Endonuclease containing a URI domain
A7A1_1811	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A7A1_1812	COG2002	toxin-antitoxin pair type II binding
A7A1_1813	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7A1_1813	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7A1_1814	COG0084	hydrolase, TatD family'
A7A1_1815	COG3583	domain protein
A7A1_1815	COG3584	3D domain protein
A7A1_1816	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7A1_1817	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A7A1_1819	COG4466	Protein conserved in bacteria
A7A1_1821	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A7A1_1822	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7A1_1823	COG0251	oxidation-reduction process
A7A1_1824	COG2088	sporulation resulting in formation of a cellular spore
A7A1_1825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A7A1_1826	COG0193	aminoacyl-tRNA hydrolase activity
A7A1_1828	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A7A1_1829	COG2002	toxin-antitoxin pair type II binding
A7A1_1830	COG2244	polysaccharide biosynthetic process
A7A1_1831	COG3956	TIGRFAM MazG family protein
A7A1_1832	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A7A1_1835	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A7A1_1836	COG1098	S1 RNA binding domain
A7A1_1837	COG0778	Nitroreductase
A7A1_1838	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A1_1839	COG1404	Belongs to the peptidase S8 family
A7A1_1840	COG0805	protein transport
A7A1_1841	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7A1_1842	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
A7A1_1843	COG0315	cyclic pyranopterin monophosphate synthase activity
A7A1_1844	COG0488	(ABC) transporter
A7A1_1845	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A7A1_1846	COG0456	acetyltransferase
A7A1_1847	COG1214	PFAM Peptidase M22, glycoprotease
A7A1_1848	COG0802	atpase or kinase
A7A1_1849	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A7A1_1850	COG1733	regulation of RNA biosynthetic process
A7A1_1851	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A7A1_1852	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A7A1_1853	COG3290	protein histidine kinase activity
A7A1_1853	COG0840	transmembrane signaling receptor activity
A7A1_1856	COG2723	6-phospho-beta-galactosidase activity
A7A1_1857	COG3842	ATPase activity
A7A1_1858	COG1846	Transcriptional regulator
A7A1_1860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A1_1861	COG0765	amino acid transport
A7A1_1862	COG0523	cobalamin synthesis protein
A7A1_1863	COG1376	ErfK ybiS ycfS ynhG family protein
A7A1_1864	COG1469	GTP cyclohydrolase I activity
A7A1_1865	COG2223	nitrite transmembrane transporter activity
A7A1_1866	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7A1_1867	COG0243	molybdopterin cofactor binding
A7A1_1868	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7A1_1869	COG2146	nitrite reductase [NAD(P)H] activity
A7A1_1870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A7A1_1870	COG1587	Uroporphyrinogen-III synthase
A7A1_1871	COG0492	ferredoxin-NADP+ reductase activity
A7A1_1872	COG2267	carboxylic ester hydrolase activity
A7A1_1873	COG0701	Predicted permease
A7A1_1874	COG3689	TIGRFAM TIGR03943 family protein
A7A1_1875	COG2508	Transcriptional regulator
A7A1_1876	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A1_1877	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_1878	COG0506	proline dehydrogenase activity
A7A1_1879	COG3541	Predicted nucleotidyltransferase
A7A1_1880	COG3458	cephalosporin-C deacetylase activity
A7A1_1881	COG0583	DNA-binding transcription factor activity
A7A1_1882	COG2226	methyltransferase
A7A1_1883	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A7A1_1884	COG1660	Displays ATPase and GTPase activities
A7A1_1885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A7A1_1886	COG1113	amino acid transport
A7A1_1887	COG3665	Urea carboxylase-associated protein
A7A1_1888	COG3403	YqcI/YcgG family
A7A1_1889	COG1280	lysine exporter protein (LysE YggA)
A7A1_1890	COG1846	Transcriptional regulator
A7A1_1891	COG2814	Major facilitator Superfamily
A7A1_1892	COG1620	l-lactate permease
A7A1_1893	COG0039	L-malate dehydrogenase activity
A7A1_1894	COG0366	Alpha amylase catalytic
A7A1_1896	COG1288	antiporter activity
A7A1_1897	COG1473	amidohydrolase
A7A1_1898	COG2113	Glycine betaine
A7A1_1899	COG4176	ABC-type proline glycine betaine transport system permease component
A7A1_1900	COG0517	IMP dehydrogenase activity
A7A1_1900	COG4175	Glycine betaine
A7A1_1901	COG0640	Transcriptional regulator
A7A1_1902	COG2814	Major facilitator Superfamily
A7A1_1903	COG0477	Major facilitator Superfamily
A7A1_1904	COG3853	Toxic anion resistance protein (TelA)
A7A1_1906	COG0861	Integral membrane protein TerC family
A7A1_1907	COG2310	stress, protein
A7A1_1908	COG2310	stress, protein
A7A1_1909	COG2310	stress, protein
A7A1_1910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A1_1911	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7A1_1912	COG1121	(ABC) transporter
A7A1_1913	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7A1_1914	COG0366	Alpha amylase catalytic
A7A1_1915	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_1916	COG0457	Tetratricopeptide repeat
A7A1_1917	COG1876	peptidase activity
A7A1_1918	COG1595	DNA-templated transcription, initiation
A7A1_1919	COG1595	DNA-templated transcription, initiation
A7A1_1921	COG0667	Aldo Keto reductase
A7A1_1922	COG1668	transmembrane transport
A7A1_1923	COG4555	ABC transporter
A7A1_1924	COG3279	Response regulator of the LytR AlgR family
A7A1_1925	COG3290	protein histidine kinase activity
A7A1_1926	COG3012	SEC-C Motif Domain Protein
A7A1_1926	COG1405	negative regulation of cell septum assembly
A7A1_1927	COG1714	RDD family
A7A1_1928	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A7A1_1929	COG0252	asparaginase activity
A7A1_1930	COG1309	transcriptional regulator
A7A1_1931	COG0477	Major facilitator Superfamily
A7A1_1932	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7A1_1933	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A7A1_1934	COG0805	protein transport
A7A1_1935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7A1_1936	COG3540	Alkaline phosphatase
A7A1_1938	COG2304	oxidoreductase activity
A7A1_1939	COG3773	Cell wall hydrolase
A7A1_1942	COG1131	(ABC) transporter
A7A1_1943	COG2205	protein histidine kinase activity
A7A1_1944	COG0745	RESPONSE REGULATOR receiver
A7A1_1945	COG0697	spore germination
A7A1_1948	COG3173	Aminoglycoside phosphotransferase
A7A1_1949	COG2721	sulfolactate sulfo-lyase activity
A7A1_1950	COG2186	Transcriptional regulator
A7A1_1951	COG4948	Mandelate Racemase Muconate Lactonizing
A7A1_1952	COG2271	Major facilitator Superfamily
A7A1_1953	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_1954	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A7A1_1955	COG1714	RDD family
A7A1_1956	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_1957	COG1309	transcriptional regulator
A7A1_1958	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_1960	COG0326	Molecular chaperone. Has ATPase activity
A7A1_1961	COG2814	Major facilitator Superfamily
A7A1_1964	COG0667	Aldo Keto reductase
A7A1_1965	COG1349	DNA-binding transcription factor activity
A7A1_1966	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_1967	COG3718	enzyme involved in inositol metabolism
A7A1_1968	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7A1_1969	COG3962	Belongs to the TPP enzyme family
A7A1_1970	COG1082	Xylose isomerase domain protein TIM barrel
A7A1_1971	COG2814	Major facilitator Superfamily
A7A1_1972	COG0673	inositol 2-dehydrogenase activity
A7A1_1973	COG1082	Xylose isomerase domain protein TIM barrel
A7A1_1974	COG1082	Xylose isomerase domain protein TIM barrel
A7A1_1975	COG0191	fructose-bisphosphate aldolase activity
A7A1_1976	COG0745	RESPONSE REGULATOR receiver
A7A1_1977	COG2205	protein histidine kinase activity
A7A1_1978	COG1136	(ABC) transporter
A7A1_1979	COG0577	efflux transmembrane transporter activity
A7A1_1980	COG5294	Protein conserved in bacteria
A7A1_1981	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A1_1987	COG0561	phosphatase activity
A7A1_1988	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A7A1_1992	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A1_1993	COG0765	amino acid transport
A7A1_1994	COG1126	abc transporter atp-binding protein
A7A1_1996	COG2079	MmgE PrpD family protein
A7A1_1997	COG3192	ethanolamine utilization protein
A7A1_1999	COG2390	Transcriptional regulator
A7A1_2000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A7A1_2001	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A7A1_2005	COG1263	PTS System
A7A1_2005	COG2190	(PTS) system
A7A1_2005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_2006	COG2723	6-phospho-beta-galactosidase activity
A7A1_2007	COG0589	response to stress
A7A1_2010	COG0697	spore germination
A7A1_2018	COG3401	FG-GAP repeat protein
A7A1_2018	COG2755	lipolytic protein G-D-S-L family
A7A1_2019	COG0513	Belongs to the DEAD box helicase family
A7A1_2020	COG2270	Major facilitator Superfamily
A7A1_2022	COG3711	transcriptional antiterminator
A7A1_2023	COG2851	Citrate transporter
A7A1_2024	COG0753	catalase activity
A7A1_2024	COG0693	protein deglycase activity
A7A1_2027	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A1_2028	COG0500	methyltransferase
A7A1_2029	COG2610	gluconate transmembrane transporter activity
A7A1_2030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A7A1_2031	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A7A1_2032	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2033	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A7A1_2034	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A7A1_2035	COG4894	glucomannan catabolic process
A7A1_2037	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7A1_2038	COG2197	response regulator
A7A1_2039	COG4585	Histidine kinase
A7A1_2041	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A7A1_2043	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A1_2044	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_2045	COG2508	Transcriptional regulator
A7A1_2046	COG3842	ATPase activity
A7A1_2047	COG0726	polysaccharide deacetylase
A7A1_2049	COG0501	Belongs to the peptidase M48B family
A7A1_2050	COG3493	citrate carrier protein
A7A1_2051	COG1271	oxidase subunit
A7A1_2052	COG1294	oxidase, subunit
A7A1_2053	COG4988	ABC transporter
A7A1_2054	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A7A1_2055	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A7A1_2056	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A7A1_2057	COG1595	DNA-templated transcription, initiation
A7A1_2061	COG1131	(ABC) transporter
A7A1_2062	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A7A1_2063	COG2814	Major facilitator Superfamily
A7A1_2064	COG0753	catalase activity
A7A1_2065	COG2094	Belongs to the DNA glycosylase MPG family
A7A1_2067	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A1_2067	COG3711	transcriptional antiterminator
A7A1_2068	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A1_2069	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A1_2070	COG1447	Phosphotransferase system cellobiose-specific component IIA
A7A1_2071	COG1486	melibiose metabolic process
A7A1_2072	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A1_2073	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A7A1_2074	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A7A1_2075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_2076	COG1696	Membrane protein involved in D-alanine export
A7A1_2077	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_2078	COG1575	Belongs to the MenA family. Type 1 subfamily
A7A1_2079	COG2357	RelA SpoT domain protein
A7A1_2080	COG2814	Major facilitator Superfamily
A7A1_2084	COG2234	aminopeptidase activity
A7A1_2085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A7A1_2086	COG1846	Transcriptional regulator
A7A1_2087	COG5522	Integral membrane protein (intg_mem_TP0381)
A7A1_2088	COG1442	glycosyl transferase family 8
A7A1_2089	COG3711	transcriptional antiterminator
A7A1_2090	COG1263	PTS System
A7A1_2090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_2091	COG1404	Belongs to the peptidase S8 family
A7A1_2092	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A1_2093	COG0346	lactoylglutathione lyase activity
A7A1_2094	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A7A1_2095	COG4895	conserved protein (DUF2196)
A7A1_2096	COG2814	Major facilitator Superfamily
A7A1_2097	COG1346	cytolysis
A7A1_2098	COG1380	Effector of murein hydrolase LrgA
A7A1_2099	COG0583	DNA-binding transcription factor activity
A7A1_2100	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A7A1_2101	COG0352	thiamine-phosphate diphosphorylase activity
A7A1_2102	COG0672	)-iron permease
A7A1_2103	COG2822	iron ion transport
A7A1_2104	COG2837	iron assimilation
A7A1_2105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A7A1_2106	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A1_2107	COG3162	membrane
A7A1_2109	COG1309	transcriptional regulator
A7A1_2110	COG2246	polysaccharide biosynthetic process
A7A1_2111	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A7A1_2112	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A7A1_2114	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A7A1_2115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A7A1_2116	COG1845	cytochrome c oxidase, subunit III
A7A1_2117	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A7A1_2119	COG0772	Belongs to the SEDS family
A7A1_2120	COG0577	efflux transmembrane transporter activity
A7A1_2121	COG1136	(ABC) transporter
A7A1_2122	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A7A1_2124	COG0697	spore germination
A7A1_2126	COG5434	Belongs to the glycosyl hydrolase 28 family
A7A1_2127	COG3104	oligopeptide transport
A7A1_2128	COG0596	Alpha beta hydrolase
A7A1_2130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A7A1_2131	COG0163	prenyltransferase activity
A7A1_2132	COG0583	DNA-binding transcription factor activity
A7A1_2133	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A1_2134	COG0765	amino acid transport
A7A1_2135	COG1126	abc transporter atp-binding protein
A7A1_2136	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A7A1_2137	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7A1_2138	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7A1_2139	COG0297	glycogen (starch) synthase activity
A7A1_2140	COG0058	SHG alpha-glucan phosphorylase activity
A7A1_2141	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A7A1_2142	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A1_2143	COG0438	transferase activity, transferring glycosyl groups
A7A1_2144	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A1_2146	COG0438	transferase activity, transferring glycosyl groups
A7A1_2147	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A1_2148	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7A1_2149	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A7A1_2150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A7A1_2151	COG1169	isochorismate synthase
A7A1_2152	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A7A1_2153	COG0596	Alpha beta hydrolase
A7A1_2154	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A7A1_2155	COG0318	PFAM AMP-dependent synthetase and ligase
A7A1_2156	COG4948	Mandelate Racemase Muconate Lactonizing
A7A1_2157	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7A1_2158	COG1121	(ABC) transporter
A7A1_2159	COG1321	iron dependent repressor
A7A1_2159	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7A1_2160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7A1_2162	COG1294	oxidase, subunit
A7A1_2163	COG1271	oxidase subunit
A7A1_2165	COG0288	reversible hydration of carbon dioxide
A7A1_2166	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A7A1_2167	COG1854	S-ribosylhomocysteine lyase activity
A7A1_2169	COG0783	Belongs to the Dps family
A7A1_2170	COG4824	toxin secretion phage lysis holin
A7A1_2171	COG0494	nUDIX hydrolase
A7A1_2172	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7A1_2173	COG1116	anion transmembrane transporter activity
A7A1_2174	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7A1_2175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7A1_2176	COG1506	peptidase
A7A1_2178	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A7A1_2179	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A7A1_2180	COG0367	asparagine synthase
A7A1_2181	COG1113	amino acid transport
A7A1_2182	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A7A1_2183	COG2267	carboxylic ester hydrolase activity
A7A1_2185	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A7A1_2186	COG1242	4 iron, 4 sulfur cluster binding
A7A1_2188	COG1725	Transcriptional regulator
A7A1_2189	COG1131	(ABC) transporter
A7A1_2192	COG1136	(ABC) transporter
A7A1_2193	COG0577	efflux transmembrane transporter activity
A7A1_2194	COG0745	RESPONSE REGULATOR receiver
A7A1_2195	COG2205	protein histidine kinase activity
A7A1_2196	COG1136	(ABC) transporter
A7A1_2197	COG0577	efflux transmembrane transporter activity
A7A1_2198	COG2433	Pfam Transposase IS66
A7A1_2199	COG2814	Major facilitator Superfamily
A7A1_2200	COG2364	Membrane
A7A1_2202	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A1_2203	COG0697	spore germination
A7A1_2205	COG2814	Major facilitator Superfamily
A7A1_2206	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A7A1_2207	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_2208	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_2209	COG3859	Proton-coupled thiamine transporter YuaJ
A7A1_2210	COG1247	-acetyltransferase
A7A1_2211	COG2268	Band 7 protein
A7A1_2212	COG1585	Membrane protein implicated in regulation of membrane protease activity
A7A1_2213	COG2318	DinB family
A7A1_2215	COG1454	alcohol dehydrogenase
A7A1_2217	COG1510	regulation of RNA biosynthetic process
A7A1_2219	COG0569	domain protein
A7A1_2220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7A1_2221	COG4682	membrane
A7A1_2222	COG1705	Flagellar rod assembly protein muramidase FlgJ
A7A1_2223	COG0477	Major facilitator Superfamily
A7A1_2225	COG5553	Cysteine dioxygenase type I
A7A1_2226	COG1968	undecaprenyl-diphosphatase activity
A7A1_2227	COG0628	permease
A7A1_2228	COG0673	inositol 2-dehydrogenase activity
A7A1_2229	COG4806	L-rhamnose isomerase
A7A1_2230	COG3254	rhamnose metabolic process
A7A1_2231	COG1070	Carbohydrate kinase
A7A1_2232	COG1349	DNA-binding transcription factor activity
A7A1_2233	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2233	COG3347	Dehydrogenase
A7A1_2234	COG0840	transmembrane signaling receptor activity
A7A1_2235	COG0840	transmembrane signaling receptor activity
A7A1_2236	COG0840	transmembrane signaling receptor activity
A7A1_2237	COG0840	transmembrane signaling receptor activity
A7A1_2240	COG0432	Pfam Uncharacterised protein family UPF0047
A7A1_2241	COG0366	Alpha amylase catalytic
A7A1_2242	COG1253	flavin adenine dinucleotide binding
A7A1_2243	COG2738	Putative neutral zinc metallopeptidase
A7A1_2244	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A7A1_2247	COG0166	Belongs to the GPI family
A7A1_2248	COG1979	alcohol dehydrogenase
A7A1_2249	COG1979	alcohol dehydrogenase
A7A1_2250	COG2155	Conserved Protein
A7A1_2251	COG1098	S1 RNA binding domain
A7A1_2252	COG0436	Aminotransferase
A7A1_2253	COG1522	sequence-specific DNA binding
A7A1_2254	COG2267	carboxylic ester hydrolase activity
A7A1_2256	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A7A1_2257	COG2205	protein histidine kinase activity
A7A1_2259	COG5018	Exonuclease
A7A1_2260	COG2814	Major facilitator Superfamily
A7A1_2261	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A1_2262	COG3011	Protein conserved in bacteria
A7A1_2264	COG3290	protein histidine kinase activity
A7A1_2265	COG4565	transcriptional regulatory protein
A7A1_2270	COG3493	citrate carrier protein
A7A1_2272	COG2111	Na H antiporter
A7A1_2272	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7A1_2273	COG2111	Na H antiporter
A7A1_2274	COG1006	Multisubunit Na H antiporter MnhC subunit
A7A1_2275	COG0651	ATP synthesis coupled electron transport
A7A1_2276	COG1863	multisubunit Na H antiporter MnhE subunit
A7A1_2277	COG2212	antiporter activity
A7A1_2278	COG1320	monovalent cation:proton antiporter activity
A7A1_2279	COG2050	protein possibly involved in aromatic compounds catabolism
A7A1_2280	COG2197	response regulator
A7A1_2281	COG4585	Histidine kinase
A7A1_2283	COG0142	geranyltranstransferase activity
A7A1_2286	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A7A1_2287	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7A1_2288	COG1335	isochorismatase
A7A1_2289	COG5506	Protein of unknown function (DUF1694)
A7A1_2292	COG0628	permease
A7A1_2295	COG1418	mRNA catabolic process
A7A1_2296	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2298	COG1511	domain protein
A7A1_2299	COG0433	COG0433 Predicted ATPase
A7A1_2299	COG1674	ftsk spoiiie
A7A1_2300	COG0433	COG0433 Predicted ATPase
A7A1_2300	COG1674	ftsk spoiiie
A7A1_2301	COG4499	WXG100 protein secretion system (Wss), protein YukC
A7A1_2302	COG5417	Belongs to the EsaB family
A7A1_2303	COG4842	Belongs to the WXG100 family
A7A1_2304	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A7A1_2304	COG2508	Transcriptional regulator
A7A1_2305	COG0686	Belongs to the AlaDH PNT family
A7A1_2306	COG5634	Uncharacterized conserved protein (DUF2278)
A7A1_2307	COG5634	Uncharacterized conserved protein (DUF2278)
A7A1_2308	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_2309	COG3433	isochorismatase activity
A7A1_2309	COG1535	isochorismatase
A7A1_2310	COG1021	2,3-dihydroxybenzoate-AMP ligase
A7A1_2311	COG1169	isochorismate synthase
A7A1_2312	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2313	COG2819	hydrolase of the alpha beta superfamily
A7A1_2314	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A7A1_2315	COG1268	BioY protein
A7A1_2316	COG2056	Na+-H+ antiporter family
A7A1_2317	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A7A1_2318	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A7A1_2319	COG3584	3D domain protein
A7A1_2322	COG1252	NADH dehydrogenase
A7A1_2323	COG0492	ferredoxin-NADP+ reductase activity
A7A1_2325	COG0516	GMP reductase activity
A7A1_2326	COG2808	Putative FMN-binding domain
A7A1_2327	COG0456	acetyltransferase
A7A1_2328	COG4837	Protein of unknown function (DUF1462)
A7A1_2329	COG1506	peptidase
A7A1_2329	COG4946	Tricorn protease homolog
A7A1_2329	COG0823	Involved in the tonB-independent uptake of proteins
A7A1_2330	COG0083	homoserine kinase activity
A7A1_2331	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7A1_2332	COG0460	homoserine dehydrogenase
A7A1_2333	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A1_2334	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A7A1_2335	COG0647	UMP catabolic process
A7A1_2336	COG2445	Protein of unknown function DUF86
A7A1_2337	COG4470	Protein conserved in bacteria
A7A1_2339	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A7A1_2340	COG0739	heme binding
A7A1_2342	COG3377	Domain of unknown function (DUF1805)
A7A1_2343	COG0737	Belongs to the 5'-nucleotidase family
A7A1_2344	COG0730	response to heat
A7A1_2345	COG1801	Protein of unknown function DUF72
A7A1_2347	COG0517	IMP dehydrogenase activity
A7A1_2348	COG0583	DNA-binding transcription factor activity
A7A1_2349	COG0716	FMN binding
A7A1_2351	COG0716	FMN binding
A7A1_2352	COG2171	N-acyltransferase activity
A7A1_2353	COG1473	amidohydrolase
A7A1_2355	COG0668	transmembrane transport
A7A1_2356	COG0450	alkyl hydroperoxide reductase
A7A1_2357	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_2360	COG0746	molybdenum cofactor guanylyltransferase activity
A7A1_2361	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7A1_2362	COG0303	'Molybdopterin
A7A1_2363	COG1763	Mo-molybdopterin cofactor biosynthetic process
A7A1_2364	COG0314	molybdopterin synthase activity
A7A1_2365	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A7A1_2366	COG1132	(ABC) transporter
A7A1_2367	COG1132	(ABC) transporter
A7A1_2369	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A7A1_2370	COG1136	(ABC) transporter
A7A1_2371	COG0577	efflux transmembrane transporter activity
A7A1_2372	COG1349	DNA-binding transcription factor activity
A7A1_2373	COG1105	Belongs to the carbohydrate kinase PfkB family
A7A1_2374	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A1_2374	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A1_2374	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A1_2375	COG0681	Belongs to the peptidase S26 family
A7A1_2377	COG0488	(ABC) transporter
A7A1_2378	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7A1_2379	COG2309	aminopeptidase activity
A7A1_2380	COG0457	Tetratricopeptide repeat
A7A1_2381	COG0456	acetyltransferase
A7A1_2382	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
A7A1_2385	COG1063	alcohol dehydrogenase
A7A1_2388	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A7A1_2396	COG3634	alkyl hydroperoxide reductase activity
A7A1_2397	COG2610	gluconate transmembrane transporter activity
A7A1_2398	COG1070	Carbohydrate kinase
A7A1_2399	COG1802	Transcriptional regulator
A7A1_2400	COG1929	Belongs to the glycerate kinase type-1 family
A7A1_2401	COG5039	Polysaccharide pyruvyl transferase
A7A1_2402	COG1346	cytolysis
A7A1_2403	COG1846	Transcriptional regulator
A7A1_2404	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2405	COG1309	transcriptional regulator
A7A1_2406	COG1917	Cupin 2, conserved barrel domain protein
A7A1_2407	COG2311	Membrane
A7A1_2408	COG1714	RDD family
A7A1_2410	COG0714	Associated with various cellular activities
A7A1_2411	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A7A1_2412	COG1305	Transglutaminase-like
A7A1_2413	COG0519	Catalyzes the synthesis of GMP from XMP
A7A1_2413	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7A1_2416	COG2252	PERMEase
A7A1_2417	COG2027	D-alanyl-D-alanine carboxypeptidase
A7A1_2418	COG2017	converts alpha-aldose to the beta-anomer
A7A1_2419	COG0534	Mate efflux family protein
A7A1_2421	COG0582	viral genome integration into host DNA
A7A1_2422	COG0166	Belongs to the GPI family
A7A1_2423	COG0405	Gamma-glutamyltransferase
A7A1_2424	COG0583	DNA-binding transcription factor activity
A7A1_2425	COG0604	alcohol dehydrogenase
A7A1_2426	COG0493	'glutamate synthase
A7A1_2427	COG0070	glutamate synthase
A7A1_2427	COG0069	glutamate synthase activity
A7A1_2427	COG0067	glutamate synthase
A7A1_2428	COG0583	DNA-binding transcription factor activity
A7A1_2429	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A7A1_2430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7A1_2432	COG0300	oxidoreductase activity
A7A1_2433	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
A7A1_2435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_2438	COG1131	(ABC) transporter
A7A1_2440	COG2814	Major facilitator Superfamily
A7A1_2441	COG1070	Carbohydrate kinase
A7A1_2442	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7A1_2443	COG0243	molybdopterin cofactor binding
A7A1_2447	COG5278	phosphoserine phosphatase activity
A7A1_2447	COG0840	transmembrane signaling receptor activity
A7A1_2448	COG2368	4-hydroxyphenylacetate
A7A1_2449	COG4305	rare lipoprotein A
A7A1_2450	COG3619	membrane
A7A1_2451	COG3866	Pectate lyase
A7A1_2452	COG2135	peptidase activity
A7A1_2454	COG2140	Oxalate decarboxylase
A7A1_2455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A7A1_2456	COG2508	Transcriptional regulator
A7A1_2457	COG2233	PERMEase
A7A1_2458	COG2233	PERMEase
A7A1_2459	COG3648	Uricase
A7A1_2459	COG3195	allantoin biosynthetic process
A7A1_2460	COG2351	hydroxyisourate hydrolase activity
A7A1_2463	COG2080	2 iron, 2 sulfur cluster binding
A7A1_2464	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A7A1_2465	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A7A1_2466	COG2068	MobA-Related Protein
A7A1_2467	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A7A1_2468	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7A1_2469	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7A1_2470	COG2356	endonuclease I
A7A1_2471	COG3842	ATPase activity
A7A1_2472	COG2188	Transcriptional regulator
A7A1_2473	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7A1_2474	COG0395	ABC-type sugar transport system, permease component
A7A1_2475	COG1175	transmembrane transport
A7A1_2476	COG1653	transport
A7A1_2477	COG2222	sugar isomerase
A7A1_2478	COG0322	excinuclease ABC activity
A7A1_2479	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7A1_2482	COG0346	lactoylglutathione lyase activity
A7A1_2483	COG0640	Transcriptional regulator
A7A1_2484	COG0719	Fe-S assembly protein
A7A1_2485	COG0822	iron-sulfur transferase activity
A7A1_2486	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7A1_2487	COG0719	Fe-S assembly protein
A7A1_2488	COG0396	ATPase activity
A7A1_2490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7A1_2491	COG1464	Belongs to the NlpA lipoprotein family
A7A1_2492	COG2011	ABC-type metal ion transport system permease component
A7A1_2493	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7A1_2495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_2496	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7A1_2498	COG0509	glycine decarboxylation via glycine cleavage system
A7A1_2499	COG1393	Belongs to the ArsC family
A7A1_2500	COG1960	acyl-CoA dehydrogenase activity
A7A1_2501	COG0183	Belongs to the thiolase family
A7A1_2502	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7A1_2502	COG1024	Enoyl-CoA hydratase
A7A1_2505	COG5577	PFAM Coat F domain
A7A1_2506	COG1846	Transcriptional regulator
A7A1_2507	COG0477	Major facilitator Superfamily
A7A1_2508	COG1942	4-Oxalocrotonate Tautomerase
A7A1_2509	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2510	COG0583	DNA-binding transcription factor activity
A7A1_2512	COG1120	ATPase activity
A7A1_2515	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2516	COG0783	Belongs to the Dps family
A7A1_2517	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7A1_2518	COG0745	RESPONSE REGULATOR receiver
A7A1_2519	COG2770	Histidine kinase
A7A1_2519	COG2205	protein histidine kinase activity
A7A1_2520	COG1309	transcriptional regulator
A7A1_2521	COG0114	fumarate hydratase activity
A7A1_2522	COG0697	spore germination
A7A1_2523	COG0814	amino acid
A7A1_2525	COG2197	response regulator
A7A1_2526	COG4585	Histidine kinase
A7A1_2527	COG4758	membrane
A7A1_2528	COG3595	metallopeptidase activity
A7A1_2529	COG1842	Phage shock protein A
A7A1_2530	COG4758	membrane
A7A1_2531	COG2814	Major facilitator Superfamily
A7A1_2532	COG2096	Adenosyltransferase
A7A1_2533	COG1120	ATPase activity
A7A1_2534	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_2535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A1_2536	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2537	COG3386	PFAM SMP-30 Gluconolaconase
A7A1_2538	COG2205	protein histidine kinase activity
A7A1_2539	COG0745	RESPONSE REGULATOR receiver
A7A1_2540	COG1191	sigma factor activity
A7A1_2541	COG2140	Oxalate decarboxylase
A7A1_2543	COG0577	efflux transmembrane transporter activity
A7A1_2544	COG1136	(ABC) transporter
A7A1_2545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A7A1_2546	COG1120	ATPase activity
A7A1_2547	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_2548	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_2549	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A1_2550	COG0531	amino acid
A7A1_2552	COG1988	membrane-bound metal-dependent
A7A1_2553	COG1368	sulfuric ester hydrolase activity
A7A1_2554	COG1910	domain protein
A7A1_2555	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7A1_2556	COG4149	molybdate abc transporter
A7A1_2557	COG0656	L-ascorbic acid biosynthetic process
A7A1_2559	COG0025	NhaP-type Na H and K H
A7A1_2560	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7A1_2561	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A7A1_2562	COG3973	AAA domain
A7A1_2564	COG2860	membrane
A7A1_2565	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A7A1_2566	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A7A1_2567	COG2217	Heavy metal translocating P-type atpase
A7A1_2568	COG2217	Heavy metal translocating P-type atpase
A7A1_2569	COG2608	mercury ion transmembrane transporter activity
A7A1_2570	COG1937	Protein conserved in bacteria
A7A1_2571	COG0673	inositol 2-dehydrogenase activity
A7A1_2572	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A7A1_2573	COG1289	transmembrane transporter activity
A7A1_2575	COG2076	Multidrug Resistance protein
A7A1_2576	COG1309	transcriptional regulator
A7A1_2577	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2579	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A7A1_2580	COG0557	exoribonuclease II activity
A7A1_2581	COG1647	Serine aminopeptidase, S33
A7A1_2582	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7A1_2583	COG0596	Alpha beta hydrolase
A7A1_2584	COG1476	TRANSCRIPTIONal
A7A1_2585	COG1396	sequence-specific DNA binding
A7A1_2586	COG1396	sequence-specific DNA binding
A7A1_2587	COG1733	regulation of RNA biosynthetic process
A7A1_2588	COG0840	transmembrane signaling receptor activity
A7A1_2589	COG1174	glycine betaine transport
A7A1_2590	COG1732	Glycine betaine
A7A1_2591	COG1174	glycine betaine transport
A7A1_2592	COG0517	IMP dehydrogenase activity
A7A1_2592	COG1125	glycine betaine transport
A7A1_2593	COG1510	regulation of RNA biosynthetic process
A7A1_2597	COG5658	integral membrane protein
A7A1_2598	COG0640	Transcriptional regulator
A7A1_2599	COG1174	glycine betaine transport
A7A1_2600	COG1732	Glycine betaine
A7A1_2601	COG1174	glycine betaine transport
A7A1_2602	COG0517	IMP dehydrogenase activity
A7A1_2602	COG1125	glycine betaine transport
A7A1_2603	COG1510	regulation of RNA biosynthetic process
A7A1_2604	COG2095	MarC family integral membrane protein
A7A1_2606	COG3064	Membrane
A7A1_2607	COG4640	response to antibiotic
A7A1_2608	COG0456	acetyltransferase
A7A1_2609	COG0148	phosphopyruvate hydratase activity
A7A1_2610	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A7A1_2611	COG0149	triose-phosphate isomerase activity
A7A1_2612	COG0126	phosphoglycerate kinase activity
A7A1_2613	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7A1_2614	COG2390	Transcriptional regulator
A7A1_2615	COG2814	Major facilitator Superfamily
A7A1_2616	COG1609	Transcriptional regulator
A7A1_2617	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A1_2618	COG0583	DNA-binding transcription factor activity
A7A1_2619	COG0697	spore germination
A7A1_2620	COG1113	amino acid transport
A7A1_2621	COG3858	chitin binding
A7A1_2622	COG1556	Lactate utilization protein
A7A1_2623	COG1139	Iron-sulfur cluster binding protein
A7A1_2624	COG0247	lactate metabolic process
A7A1_2625	COG2197	response regulator
A7A1_2626	COG4585	Histidine kinase
A7A1_2627	COG0842	Transport permease protein
A7A1_2628	COG1131	(ABC) transporter
A7A1_2629	COG0596	Alpha beta hydrolase
A7A1_2630	COG2208	phosphoserine phosphatase activity
A7A1_2631	COG3867	Arabinogalactan endo-beta-1,4-galactanase
A7A1_2632	COG1874	Beta-galactosidase
A7A1_2633	COG3833	ABC-type maltose transport systems, permease component
A7A1_2634	COG1175	transmembrane transport
A7A1_2635	COG2182	Extracellular solute-binding protein
A7A1_2636	COG1609	Transcriptional regulator
A7A1_2637	COG2186	Transcriptional regulator
A7A1_2638	COG1620	l-lactate permease
A7A1_2639	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A7A1_2641	COG5039	Polysaccharide pyruvyl transferase
A7A1_2642	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A7A1_2643	COG0110	maltose O-acetyltransferase activity
A7A1_2644	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7A1_2645	COG2244	polysaccharide biosynthetic process
A7A1_2646	COG2244	polysaccharide biosynthetic process
A7A1_2647	COG1216	Glycosyl transferase, family 2
A7A1_2648	COG5039	Polysaccharide pyruvyl transferase
A7A1_2649	COG1216	Glycosyl transferase, family 2
A7A1_2651	COG0438	transferase activity, transferring glycosyl groups
A7A1_2652	COG1215	transferase activity, transferring glycosyl groups
A7A1_2653	COG0438	transferase activity, transferring glycosyl groups
A7A1_2654	COG1086	Polysaccharide biosynthesis protein
A7A1_2655	COG0489	protein tyrosine kinase activity
A7A1_2656	COG3944	biosynthesis protein
A7A1_2657	COG1396	sequence-specific DNA binding
A7A1_2658	COG2272	Belongs to the type-B carboxylesterase lipase family
A7A1_2659	COG3479	Phenolic acid decarboxylase
A7A1_2662	COG1794	racemase activity, acting on amino acids and derivatives
A7A1_2663	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7A1_2664	COG1621	beta-fructofuranosidase activity
A7A1_2665	COG1621	beta-fructofuranosidase activity
A7A1_2666	COG0531	amino acid
A7A1_2667	COG1309	transcriptional regulator
A7A1_2668	COG2076	Multidrug Resistance protein
A7A1_2669	COG2076	Multidrug Resistance protein
A7A1_2671	COG0277	FAD linked oxidase domain protein
A7A1_2672	COG3621	Patatin-like phospholipase
A7A1_2674	COG0740	serine-type endopeptidase activity
A7A1_2675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7A1_2676	COG0366	Alpha amylase catalytic
A7A1_2677	COG1554	hydrolase, family 65, central catalytic
A7A1_2678	COG5521	maltodextrose utilization protein MalA
A7A1_2679	COG3833	ABC-type maltose transport systems, permease component
A7A1_2680	COG1175	transmembrane transport
A7A1_2681	COG2182	Extracellular solute-binding protein
A7A1_2682	COG0366	Alpha amylase catalytic
A7A1_2683	COG1609	Transcriptional regulator
A7A1_2684	COG1611	Belongs to the LOG family
A7A1_2685	COG1694	Mazg nucleotide pyrophosphohydrolase
A7A1_2686	COG0659	secondary active sulfate transmembrane transporter activity
A7A1_2687	COG0288	reversible hydration of carbon dioxide
A7A1_2688	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7A1_2689	COG0577	efflux transmembrane transporter activity
A7A1_2690	COG1136	(ABC) transporter
A7A1_2691	COG5002	protein histidine kinase activity
A7A1_2692	COG0745	RESPONSE REGULATOR receiver
A7A1_2693	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A7A1_2694	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A1_2695	COG1481	regulation of sporulation
A7A1_2696	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A7A1_2697	COG1660	Displays ATPase and GTPase activities
A7A1_2698	COG1051	belongs to the nudix hydrolase family
A7A1_2699	COG0492	ferredoxin-NADP+ reductase activity
A7A1_2700	COG3883	PFAM NLP P60 protein
A7A1_2700	COG0791	NLP P60 protein
A7A1_2701	COG0457	Tetratricopeptide repeat
A7A1_2702	COG1132	(ABC) transporter
A7A1_2707	COG0140	phosphoribosyl-ATP diphosphatase activity
A7A1_2707	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A7A1_2708	COG0107	imidazoleglycerol-phosphate synthase activity
A7A1_2709	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A7A1_2710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A7A1_2711	COG0131	Imidazoleglycerol-phosphate dehydratase
A7A1_2712	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A7A1_2713	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A7A1_2714	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A7A1_2715	COG4990	cell redox homeostasis
A7A1_2716	COG5297	Belongs to the glycosyl hydrolase family 6
A7A1_2717	COG0110	maltose O-acetyltransferase activity
A7A1_2718	COG0546	phosphoglycolate phosphatase activity
A7A1_2719	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A7A1_2720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A7A1_2721	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A7A1_2722	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A7A1_2723	COG0363	glucosamine-6-phosphate deaminase activity
A7A1_2725	COG1960	acyl-CoA dehydrogenase activity
A7A1_2726	COG3343	RNA polymerase activity
A7A1_2727	COG0504	CTP synthase activity
A7A1_2728	COG4821	SIS domain
A7A1_2729	COG2204	response regulator
A7A1_2730	COG0191	fructose-bisphosphate aldolase activity
A7A1_2731	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7A1_2732	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A7A1_2733	COG1494	fructose-1,6-bisphosphatase
A7A1_2734	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A7A1_2735	COG0254	rRNA binding
A7A1_2736	COG1435	thymidine kinase activity
A7A1_2737	COG0281	malic enzyme
A7A1_2738	COG0456	acetyltransferase
A7A1_2742	COG2720	vancomycin resistance protein
A7A1_2744	COG3655	Transcriptional regulator
A7A1_2745	COG3739	integral membrane protein
A7A1_2746	COG0583	DNA-binding transcription factor activity
A7A1_2747	COG0697	spore germination
A7A1_2749	COG0693	protein deglycase activity
A7A1_2750	COG2367	Beta-lactamase
A7A1_2751	COG4282	regulation of fungal-type cell wall biogenesis
A7A1_2755	COG3848	Pyruvate phosphate dikinase
A7A1_2755	COG0574	Belongs to the PEP-utilizing enzyme family
A7A1_2756	COG0726	polysaccharide deacetylase
A7A1_2758	COG1396	sequence-specific DNA binding
A7A1_2763	COG2723	6-phospho-beta-galactosidase activity
A7A1_2766	COG0395	ABC-type sugar transport system, permease component
A7A1_2767	COG1175	transmembrane transport
A7A1_2769	COG1940	carbohydrate kinase activity
A7A1_2771	COG5444	nuclease activity
A7A1_2772	COG4282	regulation of fungal-type cell wall biogenesis
A7A1_2773	COG1231	oxidoreductase activity
A7A1_2774	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7A1_2775	COG0662	Cupin 2, conserved barrel domain protein
A7A1_2775	COG2207	Transcriptional regulator
A7A1_2776	COG0456	acetyltransferase
A7A1_2777	COG1309	transcriptional regulator
A7A1_2778	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_2779	COG3708	Transcriptional regulator
A7A1_2780	COG2378	regulation of single-species biofilm formation
A7A1_2782	COG0640	Transcriptional regulator
A7A1_2783	COG0741	lytic transglycosylase activity
A7A1_2784	COG2322	membrane
A7A1_2787	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7A1_2788	COG3239	Fatty acid desaturase
A7A1_2789	COG4585	Histidine kinase
A7A1_2790	COG2197	response regulator
A7A1_2791	COG3584	3D domain protein
A7A1_2791	COG1388	LysM domain
A7A1_2793	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A7A1_2794	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A7A1_2796	COG0071	Belongs to the small heat shock protein (HSP20) family
A7A1_2801	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_2802	COG1657	PFAM Prenyltransferase squalene oxidase
A7A1_2803	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A7A1_2804	COG0733	neurotransmitter:sodium symporter activity
A7A1_2805	COG0385	Bile acid
A7A1_2806	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7A1_2807	COG0567	Dehydrogenase, E1 component
A7A1_2808	COG0567	Dehydrogenase, E1 component
A7A1_2809	COG4548	von Willebrand factor, type A
A7A1_2810	COG0714	Associated with various cellular activities
A7A1_2811	COG2032	superoxide dismutase activity
A7A1_2812	COG1388	LysM domain
A7A1_2812	COG0791	NLP P60 protein
A7A1_2813	COG1819	glycosyl
A7A1_2814	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A7A1_2815	COG0534	Mate efflux family protein
A7A1_2816	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_2817	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7A1_2818	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7A1_2820	COG2962	Rard protein
A7A1_2823	COG2610	gluconate transmembrane transporter activity
A7A1_2824	COG1942	4-Oxalocrotonate Tautomerase
A7A1_2825	COG1733	regulation of RNA biosynthetic process
A7A1_2826	COG0778	Nitroreductase
A7A1_2827	COG0400	carboxylic ester hydrolase activity
A7A1_2828	COG0346	lactoylglutathione lyase activity
A7A1_2829	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A1_2830	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_2830	COG0793	Belongs to the peptidase S41A family
A7A1_2831	COG2226	methyltransferase
A7A1_2833	COG1876	peptidase activity
A7A1_2834	COG0813	purine-nucleoside phosphorylase activity
A7A1_2836	COG0671	phosphoesterase, PA-phosphatase related
A7A1_2839	COG4479	Belongs to the UPF0346 family
A7A1_2840	COG1509	lysine 2,3-aminomutase activity
A7A1_2841	COG0456	acetyltransferase
A7A1_2842	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7A1_2843	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A7A1_2844	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A7A1_2845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7A1_2847	COG0456	acetyltransferase
A7A1_2848	COG0463	Glycosyl transferase, family 2
A7A1_2851	COG4641	Protein conserved in bacteria
A7A1_2852	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
A7A1_2853	COG1086	Polysaccharide biosynthesis protein
A7A1_2854	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7A1_2855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7A1_2856	COG1846	Transcriptional regulator
A7A1_2857	COG0534	Mate efflux family protein
A7A1_2859	COG4698	Protein conserved in bacteria
A7A1_2860	COG2755	lipolytic protein G-D-S-L family
A7A1_2861	COG1999	signal sequence binding
A7A1_2863	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A7A1_2864	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A7A1_2865	COG1272	protein, Hemolysin III
A7A1_2866	COG0204	Acyl-transferase
A7A1_2867	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7A1_2868	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A7A1_2869	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A7A1_2871	COG2521	methyltransferase
A7A1_2871	COG2136	Putative SAM-dependent methyltransferase
A7A1_2873	COG0129	dihydroxy-acid dehydratase activity
A7A1_2874	COG1413	lyase activity
A7A1_2875	COG1418	mRNA catabolic process
A7A1_2876	COG0386	Belongs to the glutathione peroxidase family
A7A1_2877	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A7A1_2878	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A7A1_2879	COG1278	Cold shock
A7A1_2883	COG0328	RNA-DNA hybrid ribonuclease activity
A7A1_2884	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A7A1_2885	COG0328	RNA-DNA hybrid ribonuclease activity
A7A1_2887	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7A1_2889	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7A1_2890	COG1755	Isoprenylcysteine carboxyl methyltransferase
A7A1_2891	COG3424	synthase
A7A1_2892	COG2233	PERMEase
A7A1_2893	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7A1_2894	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A7A1_2896	COG0800	Aldolase
A7A1_2897	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7A1_2898	COG1609	Transcriptional regulator
A7A1_2899	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
A7A1_2900	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_2901	COG1199	ATP-dependent helicase activity
A7A1_2905	COG0116	Belongs to the methyltransferase superfamily
A7A1_2908	COG4474	Belongs to the UPF0398 family
A7A1_2910	COG3359	exonuclease
A7A1_2911	COG1205	dead DEAH box helicase
A7A1_2911	COG1111	helicase
A7A1_2912	COG2190	(PTS) system
A7A1_2913	COG0071	Belongs to the small heat shock protein (HSP20) family
A7A1_2920	COG3331	DNA recombination
A7A1_2921	COG4499	WXG100 protein secretion system (Wss), protein YukC
A7A1_2921	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A1_2923	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7A1_2924	COG3935	DnaD domain protein
A7A1_2925	COG0017	Asparaginyl-tRNA synthetase
A7A1_2926	COG0436	Aminotransferase
A7A1_2927	COG5353	protein conserved in bacteria
A7A1_2929	COG1199	ATP-dependent helicase activity
A7A1_2929	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A7A1_2930	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
A7A1_2931	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A7A1_2932	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A7A1_2933	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A7A1_2933	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A7A1_2934	COG0617	tRNA 3'-terminal CCA addition
A7A1_2935	COG0438	transferase activity, transferring glycosyl groups
A7A1_2936	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7A1_2937	COG1803	Methylglyoxal synthase
A7A1_2938	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A7A1_2939	COG1694	Mazg nucleotide pyrophosphohydrolase
A7A1_2940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A1_2942	COG4347	Protein of unknown function (DUF1405)
A7A1_2943	COG2010	Cytochrome c
A7A1_2943	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7A1_2944	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7A1_2945	COG0723	plastoquinol--plastocyanin reductase activity
A7A1_2947	COG5582	Belongs to the UPF0302 family
A7A1_2948	COG0457	Tetratricopeptide repeat
A7A1_2949	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A7A1_2950	COG0287	Prephenate dehydrogenase
A7A1_2951	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7A1_2952	COG0159	tryptophan synthase activity
A7A1_2953	COG0133	tryptophan synthase activity
A7A1_2954	COG0135	phosphoribosylanthranilate isomerase activity
A7A1_2956	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7A1_2957	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7A1_2958	COG4401	Chorismate mutase type I
A7A1_2959	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A7A1_2960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A7A1_2961	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A7A1_2962	COG0105	UTP biosynthetic process
A7A1_2963	COG0142	geranyltranstransferase activity
A7A1_2964	COG2226	methyltransferase
A7A1_2965	COG0142	geranyltranstransferase activity
A7A1_2967	COG0302	gtp cyclohydrolase
A7A1_2968	COG0776	regulation of translation
A7A1_2969	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7A1_2972	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A7A1_2973	COG1160	GTP binding
A7A1_2976	COG1304	FMN binding
A7A1_2977	COG0539	negative regulation of cytoplasmic translation
A7A1_2978	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A7A1_2980	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
A7A1_2981	COG2959	enzyme of heme biosynthesis
A7A1_2982	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_2982	COG3773	Cell wall hydrolase
A7A1_2983	COG2339	peptidase activity
A7A1_2984	COG0492	ferredoxin-NADP+ reductase activity
A7A1_2985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7A1_2986	COG4862	establishment of competence for transformation
A7A1_2987	COG1408	metallophosphoesterase
A7A1_2989	COG1388	LysM domain
A7A1_2990	COG1266	CAAX protease self-immunity
A7A1_2991	COG0514	ATP-dependent DNA helicase (RecQ)
A7A1_2992	COG4955	Helix-turn-helix domain
A7A1_2993	COG1141	Ferredoxin
A7A1_2994	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A7A1_2996	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7A1_2997	COG0710	3-dehydroquinate dehydratase activity
A7A1_2999	COG1595	DNA-templated transcription, initiation
A7A1_3000	COG5002	protein histidine kinase activity
A7A1_3001	COG0745	RESPONSE REGULATOR receiver
A7A1_3002	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7A1_3003	COG1333	cytochrome c biogenesis protein
A7A1_3004	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_3005	COG1187	pseudouridine synthase activity
A7A1_3006	COG0700	Nucleoside recognition
A7A1_3007	COG2715	membrane protein required for spore maturation
A7A1_3008	COG1686	Belongs to the peptidase S11 family
A7A1_3010	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A7A1_3011	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A7A1_3012	COG1547	Domain of unknown function (DUF309)
A7A1_3013	COG0456	acetyltransferase
A7A1_3014	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A7A1_3015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7A1_3015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7A1_3016	COG0307	riboflavin synthase, alpha
A7A1_3017	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7A1_3017	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7A1_3021	COG0681	Belongs to the peptidase S26 family
A7A1_3025	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
A7A1_3029	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A7A1_3030	COG4086	secreted protein
A7A1_3031	COG0019	diaminopimelate decarboxylase activity
A7A1_3032	COG0697	spore germination
A7A1_3035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A1_3039	COG1191	sigma factor activity
A7A1_3040	COG2172	sigma factor antagonist activity
A7A1_3041	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_3042	COG1686	Belongs to the peptidase S11 family
A7A1_3043	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A7A1_3044	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A7A1_3045	COG4974	Belongs to the 'phage' integrase family
A7A1_3046	COG0735	belongs to the Fur family
A7A1_3047	COG1300	Membrane
A7A1_3049	COG0281	malic enzyme
A7A1_3050	COG1757	Na H antiporter
A7A1_3051	COG1027	Aspartate ammonia-lyase
A7A1_3052	COG0252	asparaginase activity
A7A1_3053	COG1396	sequence-specific DNA binding
A7A1_3054	COG1379	DNA repair
A7A1_3055	COG0494	nUDIX hydrolase
A7A1_3056	COG0667	Aldo Keto reductase
A7A1_3058	COG1073	alpha beta
A7A1_3060	COG4918	Iron-sulphur cluster biosynthesis
A7A1_3061	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A7A1_3061	COG0456	acetyltransferase
A7A1_3062	COG2329	Antibiotic biosynthesis monooxygenase
A7A1_3063	COG0456	acetyltransferase
A7A1_3065	COG2329	Antibiotic biosynthesis monooxygenase
A7A1_3067	COG2755	lipolytic protein G-D-S-L family
A7A1_3068	COG1414	Transcriptional regulator
A7A1_3069	COG1984	allophanate hydrolase subunit 2
A7A1_3070	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7A1_3071	COG4336	lyase activity
A7A1_3072	COG1914	H( )-stimulated, divalent metal cation uptake system
A7A1_3073	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A7A1_3074	COG0561	phosphatase activity
A7A1_3075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A7A1_3076	COG0412	Dienelactone hydrolase
A7A1_3077	COG0681	Belongs to the peptidase S26 family
A7A1_3078	COG0473	3-isopropylmalate dehydrogenase activity
A7A1_3079	COG0246	Mannitol dehydrogenase
A7A1_3080	COG2213	PTS system mannitol-specific
A7A1_3082	COG1349	DNA-binding transcription factor activity
A7A1_3083	COG2372	response to copper ion
A7A1_3083	COG1276	copper resistance
A7A1_3084	COG4549	nuclear export factor GLE1
A7A1_3085	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3086	COG4975	Glucose uptake
A7A1_3087	COG1012	belongs to the aldehyde dehydrogenase family
A7A1_3088	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7A1_3089	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A1_3090	COG0640	Transcriptional regulator
A7A1_3091	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A7A1_3092	COG0778	Nitroreductase
A7A1_3093	COG1309	transcriptional regulator
A7A1_3094	COG2814	Major facilitator Superfamily
A7A1_3095	COG4607	ABC-type enterochelin transport system periplasmic component
A7A1_3096	COG4604	ABC transporter, ATP-binding protein
A7A1_3097	COG4605	iron ion homeostasis
A7A1_3098	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A1_3099	COG0527	aspartate kinase activity
A7A1_3101	COG0457	Tetratricopeptide repeat
A7A1_3102	COG3850	Histidine kinase
A7A1_3102	COG5002	protein histidine kinase activity
A7A1_3103	COG0745	RESPONSE REGULATOR receiver
A7A1_3104	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
A7A1_3107	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7A1_3108	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A7A1_3109	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7A1_3110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A7A1_3111	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7A1_3112	COG0047	phosphoribosylformylglycinamidine synthase activity
A7A1_3113	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7A1_3114	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A7A1_3115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A7A1_3116	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A7A1_3117	COG0138	bifunctional purine biosynthesis protein purh
A7A1_3118	COG0151	Belongs to the GarS family
A7A1_3119	COG1522	sequence-specific DNA binding
A7A1_3120	COG0531	amino acid
A7A1_3121	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A7A1_3122	COG1470	cell adhesion involved in biofilm formation
A7A1_3123	COG4496	protein, YerC YecD
A7A1_3124	COG0069	glutamate synthase activity
A7A1_3125	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A7A1_3126	COG0210	DNA helicase
A7A1_3127	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A7A1_3128	COG4851	CamS sex pheromone cAM373 precursor
A7A1_3129	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A1_3130	COG1285	pathogenesis
A7A1_3131	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A1_3132	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7A1_3133	COG0154	amidase activity
A7A1_3134	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7A1_3135	COG1309	transcriptional regulator
A7A1_3136	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7A1_3137	COG1597	lipid kinase activity
A7A1_3138	COG0626	cystathionine gamma-synthase activity
A7A1_3139	COG0626	cystathionine gamma-synthase activity
A7A1_3140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_3141	COG5505	Protein of unknown function (DUF819)
A7A1_3142	COG4326	sporulation control protein
A7A1_3144	COG3340	Belongs to the peptidase S51 family
A7A1_3145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7A1_3146	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A7A1_3147	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A7A1_3148	COG3611	Membrane attachment protein
A7A1_3149	COG1484	DNA-dependent DNA replication
A7A1_3150	COG0398	Pfam SNARE associated Golgi protein
A7A1_3152	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7A1_3154	COG3275	phosphorelay sensor kinase activity
A7A1_3155	COG3279	Response regulator of the LytR AlgR family
A7A1_3156	COG1380	Effector of murein hydrolase LrgA
A7A1_3157	COG1346	cytolysis
A7A1_3160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A7A1_3161	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A7A1_3162	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A7A1_3163	COG3326	Membrane
A7A1_3165	COG1363	Peptidase, m42
A7A1_3166	COG3507	Belongs to the glycosyl hydrolase 43 family
A7A1_3167	COG2160	L-arabinose isomerase activity
A7A1_3168	COG1069	ribulokinase activity
A7A1_3169	COG0235	Class ii aldolase
A7A1_3170	COG0647	UMP catabolic process
A7A1_3171	COG0371	Dehydrogenase
A7A1_3172	COG1653	transport
A7A1_3173	COG1175	transmembrane transport
A7A1_3174	COG0395	ABC-type sugar transport system, permease component
A7A1_3175	COG3534	alpha-L-arabinofuranosidase
A7A1_3176	COG1966	Carbon starvation protein
A7A1_3177	COG0346	lactoylglutathione lyase activity
A7A1_3178	COG0247	lactate metabolic process
A7A1_3179	COG0277	FAD linked oxidase domain protein
A7A1_3180	COG3835	regulator
A7A1_3182	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7A1_3183	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A7A1_3184	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7A1_3184	COG0072	phenylalanine-tRNA ligase activity
A7A1_3185	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A7A1_3186	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A7A1_3187	COG1286	toxin biosynthetic process
A7A1_3188	COG1796	DNA polymerase
A7A1_3188	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7A1_3189	COG1193	negative regulation of DNA recombination
A7A1_3190	COG3766	membrane
A7A1_3191	COG0318	PFAM AMP-dependent synthetase and ligase
A7A1_3192	COG1309	transcriptional regulator
A7A1_3193	COG1024	Enoyl-CoA hydratase
A7A1_3194	COG2086	electron transfer activity
A7A1_3195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7A1_3196	COG3534	alpha-L-arabinofuranosidase
A7A1_3197	COG3118	belongs to the thioredoxin family
A7A1_3199	COG0481	GTPase activity
A7A1_3200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7A1_3201	COG1420	regulation of RNA biosynthetic process
A7A1_3202	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A7A1_3203	COG0443	Heat shock 70 kDa protein
A7A1_3204	COG0484	heat shock protein binding
A7A1_3205	COG2264	protein methyltransferase activity
A7A1_3206	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A7A1_3207	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7A1_3208	COG1283	sodium-dependent phosphate transmembrane transporter activity
A7A1_3209	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A7A1_3210	COG1610	YqeY-like protein
A7A1_3211	COG1030	water channel activity
A7A1_3212	COG4864	UPF0365 protein
A7A1_3215	COG0561	phosphatase activity
A7A1_3216	COG1702	phosphate starvation-inducible protein PhoH
A7A1_3217	COG1480	7TM receptor with intracellular HD hydrolase
A7A1_3218	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A7A1_3219	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A7A1_3220	COG0295	cytidine deaminase activity
A7A1_3221	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A7A1_3222	COG1381	Involved in DNA repair and RecF pathway recombination
A7A1_3223	COG0752	glycyl-tRNA synthetase alpha subunit
A7A1_3224	COG0751	glycine-tRNA ligase activity
A7A1_3225	COG0517	IMP dehydrogenase activity
A7A1_3226	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A7A1_3227	COG1671	Belongs to the UPF0178 family
A7A1_3228	COG0358	DNA primase activity
A7A1_3229	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A7A1_3230	COG2010	Cytochrome c
A7A1_3231	COG2384	SAM-dependent methyltransferase
A7A1_3232	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A7A1_3233	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A7A1_3235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7A1_3236	COG0784	Response regulator, receiver
A7A1_3237	COG4191	Histidine kinase
A7A1_3238	COG4191	Histidine kinase
A7A1_3239	COG2066	Belongs to the glutaminase family
A7A1_3240	COG1115	amino acid carrier protein
A7A1_3241	COG2040	homocysteine
A7A1_3242	COG0833	amino acid
A7A1_3243	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A1_3246	COG0363	glucosamine-6-phosphate deaminase activity
A7A1_3247	COG1263	PTS System
A7A1_3247	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A1_3247	COG2190	(PTS) system
A7A1_3248	COG1301	dicarboxylic acid transport
A7A1_3250	COG2312	Erythromycin esterase
A7A1_3252	COG0688	phosphatidylethanolamine metabolic process
A7A1_3253	COG0586	Pfam SNARE associated Golgi protein
A7A1_3254	COG1183	phosphatidylcholine synthase activity
A7A1_3255	COG0596	Alpha beta hydrolase
A7A1_3257	COG3591	Belongs to the peptidase S1B family
A7A1_3258	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A7A1_3259	COG5444	nuclease activity
A7A1_3260	COG1397	ADP-ribosylglycohydrolase
A7A1_3261	COG1917	Cupin 2, conserved barrel domain protein
A7A1_3261	COG2207	Transcriptional regulator
A7A1_3262	COG0697	spore germination
A7A1_3263	COG3409	Peptidoglycan-binding domain 1 protein
A7A1_3265	COG2271	Major facilitator Superfamily
A7A1_3266	COG0456	acetyltransferase
A7A1_3266	COG1846	Transcriptional regulator
A7A1_3268	COG2271	Major facilitator Superfamily
A7A1_3269	COG0584	glycerophosphoryl diester phosphodiesterase
A7A1_3270	COG0531	amino acid
A7A1_3272	COG2124	cytochrome p450
A7A1_3273	COG2602	Beta-lactamase
A7A1_3275	COG1113	amino acid transport
A7A1_3278	COG0515	serine threonine protein kinase
A7A1_3280	COG0642	Histidine kinase
A7A1_3281	COG0745	RESPONSE REGULATOR receiver
A7A1_3282	COG0596	Alpha beta hydrolase
A7A1_3283	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A1_3284	COG1413	lyase activity
A7A1_3286	COG1131	(ABC) transporter
A7A1_3287	COG1266	CAAX protease self-immunity
A7A1_3288	COG1266	CAAX protease self-immunity
A7A1_3289	COG0535	radical SAM domain protein
A7A1_3291	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7A1_3292	COG2814	Major facilitator Superfamily
A7A1_3293	COG0640	Transcriptional regulator
A7A1_3294	COG5609	conserved protein (DUF2294)
A7A1_3296	COG0288	reversible hydration of carbon dioxide
A7A1_3297	COG3002	Belongs to the UPF0753 family
A7A1_3298	COG3002	Belongs to the UPF0753 family
A7A1_3299	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7A1_3300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7A1_3301	COG2169	Transcriptional regulator
A7A1_3302	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A7A1_3304	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7A1_3305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7A1_3306	COG4856	YbbR-like protein
A7A1_3307	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A7A1_3308	COG5662	AntiSigma factor
A7A1_3309	COG1595	DNA-templated transcription, initiation
A7A1_3314	COG0756	dUTP diphosphatase activity
A7A1_3316	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A7A1_3317	COG2814	Major facilitator Superfamily
A7A1_3318	COG1525	nuclease
A7A1_3319	COG1070	Carbohydrate kinase
A7A1_3320	COG2115	Belongs to the xylose isomerase family
A7A1_3321	COG1940	carbohydrate kinase activity
A7A1_3322	COG3507	Belongs to the glycosyl hydrolase 43 family
A7A1_3323	COG2211	Major facilitator Superfamily
A7A1_3324	COG0135	phosphoribosylanthranilate isomerase activity
A7A1_3327	COG3655	Transcriptional regulator
A7A1_3330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A1_3331	COG4282	regulation of fungal-type cell wall biogenesis
A7A1_3335	COG0174	glutamine synthetase
A7A1_3336	COG0789	Transcriptional regulator
A7A1_3337	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A7A1_3338	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7A1_3339	COG0464	growth
A7A1_3340	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A1_3341	COG4112	unkown
A7A1_3342	COG1780	Probably involved in ribonucleotide reductase function
A7A1_3345	COG1923	regulation of RNA biosynthetic process
A7A1_3346	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A7A1_3349	COG2076	Multidrug Resistance protein
A7A1_3350	COG2076	Multidrug Resistance protein
A7A1_3351	COG1764	response to oxidative stress
A7A1_3352	COG4195	phage-related replication protein
A7A1_3354	COG1404	Belongs to the peptidase S8 family
A7A1_3355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_3357	COG2124	cytochrome p450
A7A1_3358	COG3321	synthase
A7A1_3358	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3358	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7A1_3358	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A7A1_3359	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3359	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3359	COG4221	oxidoreductase activity
A7A1_3359	COG3321	synthase
A7A1_3360	COG3321	synthase
A7A1_3360	COG4221	oxidoreductase activity
A7A1_3360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3360	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3361	COG4221	oxidoreductase activity
A7A1_3361	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3361	COG3321	synthase
A7A1_3361	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3362	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3362	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3362	COG3321	synthase
A7A1_3362	COG4221	oxidoreductase activity
A7A1_3363	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3363	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3363	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A1_3363	COG3321	synthase
A7A1_3363	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3364	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A1_3364	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3364	COG3321	synthase
A7A1_3364	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3364	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A1_3365	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3365	COG3321	synthase
A7A1_3365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3366	COG4221	oxidoreductase activity
A7A1_3366	COG0300	oxidoreductase activity
A7A1_3366	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3366	COG3321	synthase
A7A1_3367	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3367	COG0300	oxidoreductase activity
A7A1_3367	COG3321	synthase
A7A1_3367	COG4221	oxidoreductase activity
A7A1_3368	COG0300	oxidoreductase activity
A7A1_3368	COG3321	synthase
A7A1_3368	COG0318	PFAM AMP-dependent synthetase and ligase
A7A1_3368	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A1_3368	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3369	COG1024	Enoyl-CoA hydratase
A7A1_3370	COG1024	Enoyl-CoA hydratase
A7A1_3371	COG3425	synthase
A7A1_3372	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7A1_3373	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3374	COG2070	2-Nitropropane dioxygenase
A7A1_3374	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7A1_3375	COG3321	synthase
A7A1_3376	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7A1_3378	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_3379	COG3226	Transcriptional regulator
A7A1_3382	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A7A1_3383	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7A1_3385	COG4550	Control of competence regulator ComK, YlbF/YmcA
A7A1_3386	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7A1_3387	COG0156	8-amino-7-oxononanoate synthase activity
A7A1_3388	COG1063	alcohol dehydrogenase
A7A1_3389	COG2359	stage V sporulation protein S
A7A1_3390	COG1692	metallophosphoesterase
A7A1_3391	COG1418	mRNA catabolic process
A7A1_3392	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7A1_3393	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A7A1_3394	COG1058	Belongs to the CinA family
A7A1_3394	COG1546	Belongs to the CinA family
A7A1_3395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A7A1_3396	COG1426	Protein conserved in bacteria
A7A1_3399	COG0300	oxidoreductase activity
A7A1_3400	COG0612	Peptidase, M16
A7A1_3401	COG0612	Peptidase, M16
A7A1_3402	COG2814	Major facilitator Superfamily
A7A1_3403	COG2188	Transcriptional regulator
A7A1_3404	COG1674	ftsk spoiiie
A7A1_3404	COG4980	gas vesicle protein
A7A1_3405	COG0740	serine-type endopeptidase activity
A7A1_3406	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7A1_3407	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7A1_3408	COG0527	aspartate kinase activity
A7A1_3409	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A7A1_3410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7A1_3411	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7A1_3412	COG1873	PFAM PRC-barrel domain
A7A1_3413	COG0612	Peptidase, M16
A7A1_3414	COG0726	polysaccharide deacetylase
A7A1_3415	COG1185	polyribonucleotide nucleotidyltransferase activity
A7A1_3416	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A7A1_3417	COG0196	riboflavin kinase activity
A7A1_3418	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7A1_3419	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A7A1_3420	COG1550	Protein conserved in bacteria
A7A1_3421	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A7A1_3422	COG1358	cellular component organization or biogenesis
A7A1_3423	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A7A1_3424	COG0195	Participates in both transcription termination and antitermination
A7A1_3425	COG0779	Required for maturation of 30S ribosomal subunits
A7A1_3426	COG2176	DNA-directed DNA polymerase activity
A7A1_3427	COG0442	prolyl-tRNA aminoacylation
A7A1_3428	COG0750	zinc metalloprotease
A7A1_3429	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A7A1_3430	COG4589	Belongs to the CDS family
A7A1_3431	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7A1_3432	COG0233	cytoplasmic translational termination
A7A1_3433	COG0528	UMP kinase activity
A7A1_3434	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A7A1_3435	COG0052	Belongs to the universal ribosomal protein uS2 family
A7A1_3437	COG1191	sigma factor activity
A7A1_3438	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A7A1_3439	COG1776	CheC inhibitor of MCP methylation
A7A1_3440	COG0835	chemotaxis
A7A1_3441	COG2198	Histidine kinase
A7A1_3441	COG0643	Histidine kinase
A7A1_3442	COG0643	Histidine kinase
A7A1_3442	COG2198	Histidine kinase
A7A1_3443	COG2201	protein-glutamate methylesterase activity
A7A1_3444	COG0455	bacterial-type flagellum organization
A7A1_3445	COG1419	protein localization to endoplasmic reticulum
A7A1_3446	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7A1_3447	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7A1_3448	COG1684	flagellar biosynthetic protein fliR
A7A1_3449	COG1987	bacterial-type flagellum assembly
A7A1_3450	COG1338	Plays a role in the flagellum-specific transport system
A7A1_3451	COG3190	flagellar
A7A1_3452	COG2201	protein-glutamate methylesterase activity
A7A1_3453	COG1776	CheC inhibitor of MCP methylation
A7A1_3453	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7A1_3454	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7A1_3455	COG1580	Controls the rotational direction of flagella during chemotaxis
A7A1_3456	COG4786	Flagellar basal body rod
A7A1_3457	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A7A1_3458	COG3144	bacterial-type flagellum assembly
A7A1_3459	COG3334	PFAM MgtE intracellular
A7A1_3460	COG2882	bacterial-type flagellum organization
A7A1_3461	COG1157	protein secretion by the type III secretion system
A7A1_3462	COG1317	bacterial-type flagellum organization
A7A1_3463	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7A1_3464	COG1766	The M ring may be actively involved in energy transduction
A7A1_3465	COG1677	Flagellar hook-basal body complex protein FliE
A7A1_3466	COG1558	bacterial-type flagellum-dependent cell motility
A7A1_3467	COG1815	bacterial-type flagellum-dependent cell motility
A7A1_3468	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
A7A1_3469	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A7A1_3470	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A7A1_3471	COG4974	Belongs to the 'phage' integrase family
A7A1_3472	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A7A1_3473	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7A1_3474	COG0758	DNA mediated transformation
A7A1_3475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A7A1_3476	COG0045	succinate-CoA ligase (ADP-forming) activity
A7A1_3477	COG2257	FlhB HrpN YscU SpaS Family
A7A1_3479	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A7A1_3480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A7A1_3481	COG0335	large ribosomal subunit rRNA binding
A7A1_3482	COG0336	Belongs to the RNA methyltransferase TrmD family
A7A1_3483	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A7A1_3485	COG1837	Belongs to the UPF0109 family
A7A1_3486	COG0228	four-way junction DNA binding
A7A1_3487	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7A1_3488	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
A7A1_3490	COG0552	protein localization to endoplasmic reticulum
A7A1_3491	COG1196	nuclear chromosome segregation
A7A1_3492	COG0571	ribonuclease III activity
A7A1_3493	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A1_3494	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7A1_3496	COG0416	fatty acid biosynthetic process
A7A1_3497	COG1349	DNA-binding transcription factor activity
A7A1_3497	COG2050	protein possibly involved in aromatic compounds catabolism
A7A1_3498	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A7A1_3499	COG1760	l-serine dehydratase
A7A1_3500	COG1760	l-serine dehydratase
A7A1_3501	COG1461	Dihydroxyacetone kinase
A7A1_3502	COG1302	Protein conserved in bacteria
A7A1_3505	COG1564	THIamine pyrophosphokinase
A7A1_3506	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7A1_3507	COG1162	GTPase activity
A7A1_3508	COG2815	serine threonine protein kinase
A7A1_3508	COG0515	serine threonine protein kinase
A7A1_3509	COG0631	protein serine/threonine phosphatase activity
A7A1_3510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A7A1_3511	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7A1_3511	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7A1_3512	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A7A1_3513	COG0242	peptide deformylase activity
A7A1_3514	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7A1_3515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7A1_3516	COG1758	RNA polymerase activity
A7A1_3517	COG0194	GDP metabolic process
A7A1_3518	COG2052	Domain of unknown function (DUF370)
A7A1_3519	COG1561	YicC-like family, N-terminal region
A7A1_3520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7A1_3522	COG1648	precorrin-2 dehydrogenase activity
A7A1_3523	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
A7A1_3524	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A7A1_3525	COG0529	Catalyzes the synthesis of activated sulfate
A7A1_3526	COG2046	Belongs to the sulfate adenylyltransferase family
A7A1_3527	COG0306	phosphate transporter
A7A1_3528	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A7A1_3530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A1_3531	COG0735	belongs to the Fur family
A7A1_3532	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
A7A1_3533	COG4709	membrane
A7A1_3534	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A7A1_3535	COG1388	LysM domain
A7A1_3537	COG5521	maltodextrose utilization protein MalA
A7A1_3538	COG2839	Protein conserved in bacteria
A7A1_3539	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A7A1_3540	COG0477	Major facilitator Superfamily
A7A1_3542	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7A1_3543	COG0573	inorganic phosphate transmembrane transporter activity
A7A1_3544	COG0581	inorganic phosphate transmembrane transporter activity
A7A1_3545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7A1_3546	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7A1_3547	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A7A1_3550	COG0438	transferase activity, transferring glycosyl groups
A7A1_3551	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A7A1_3552	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7A1_3554	COG0457	Tetratricopeptide repeat
A7A1_3554	COG0705	Rhomboid family
A7A1_3555	COG4483	Protein conserved in bacteria
A7A1_3556	COG1940	carbohydrate kinase activity
A7A1_3557	COG1368	sulfuric ester hydrolase activity
A7A1_3558	COG2866	Carboxypeptidase
A7A1_3560	COG0011	TIGRFAM Protein of
A7A1_3562	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_3564	COG1393	Belongs to the ArsC family
A7A1_3565	COG1366	Belongs to the anti-sigma-factor antagonist family
A7A1_3566	COG1253	flavin adenine dinucleotide binding
A7A1_3567	COG0598	Magnesium transport protein CorA
A7A1_3568	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A7A1_3569	COG1459	type II secretion system
A7A1_3570	COG4537	Required for transformation and DNA binding
A7A1_3571	COG4970	Tfp pilus assembly protein FimT
A7A1_3573	COG4940	Competence protein ComGF
A7A1_3578	COG0681	Belongs to the peptidase S26 family
A7A1_3580	COG1396	sequence-specific DNA binding
A7A1_3583	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7A1_3585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A7A1_3586	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7A1_3587	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7A1_3588	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A1_3589	COG0095	Lipoate-protein ligase
A7A1_3590	COG1321	iron dependent repressor
A7A1_3591	COG1752	Esterase of the alpha-beta hydrolase superfamily
A7A1_3593	COG3872	metal-dependent enzyme
A7A1_3595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A7A1_3596	COG0006	proline dipeptidase activity
A7A1_3597	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A7A1_3599	COG3854	ATPases associated with a variety of cellular activities
A7A1_3607	COG0511	ligase activity, forming carbon-carbon bonds
A7A1_3608	COG0439	Biotin carboxylase
A7A1_3609	COG1302	Protein conserved in bacteria
A7A1_3610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7A1_3611	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A7A1_3612	COG1570	exodeoxyribonuclease VII activity
A7A1_3613	COG1722	exodeoxyribonuclease VII activity
A7A1_3614	COG0142	geranyltranstransferase activity
A7A1_3615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A7A1_3616	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A7A1_3617	COG1438	arginine binding
A7A1_3618	COG0497	DNA recombination
A7A1_3619	COG0750	zinc metalloprotease
A7A1_3620	COG0745	RESPONSE REGULATOR receiver
A7A1_3621	COG1902	pentaerythritol trinitrate reductase activity
A7A1_3623	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A1_3624	COG0584	glycerophosphoryl diester phosphodiesterase
A7A1_3625	COG0183	Belongs to the thiolase family
A7A1_3626	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7A1_3627	COG1960	acyl-CoA dehydrogenase activity
A7A1_3628	COG0372	Belongs to the citrate synthase family
A7A1_3629	COG2079	MmgE PrpD family protein
A7A1_3630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A7A1_3633	COG3290	protein histidine kinase activity
A7A1_3633	COG3829	transcription factor binding
A7A1_3634	COG0280	phosphate acetyltransferase
A7A1_3635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7A1_3636	COG3426	butyrate kinase activity
A7A1_3637	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7A1_3638	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7A1_3639	COG0022	dehydrogenase e1 component
A7A1_3640	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7A1_3641	COG4978	Transcriptional regulator
A7A1_3641	COG0789	Transcriptional regulator
A7A1_3642	COG2814	Major facilitator Superfamily
A7A1_3643	COG1597	lipid kinase activity
A7A1_3645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A1_3646	COG0765	amino acid transport
A7A1_3647	COG1126	abc transporter atp-binding protein
A7A1_3648	COG4129	membrane
A7A1_3649	COG1376	ErfK ybiS ycfS ynhG family protein
A7A1_3650	COG0346	lactoylglutathione lyase activity
A7A1_3651	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7A1_3652	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7A1_3653	COG3361	conserved protein (COG2071)
A7A1_3654	COG0706	membrane insertase activity
A7A1_3656	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7A1_3657	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A7A1_3658	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A7A1_3659	COG1234	tRNA 3'-trailer cleavage
A7A1_3661	COG0596	Alpha beta hydrolase
A7A1_3662	COG1902	pentaerythritol trinitrate reductase activity
A7A1_3663	COG4187	Peptidase family M20/M25/M40
A7A1_3664	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7A1_3665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A1_3666	COG0300	oxidoreductase activity
A7A1_3667	COG3048	D-serine ammonia-lyase activity
A7A1_3668	COG1072	(Pantothenic acid kinase))
A7A1_3669	COG0346	lactoylglutathione lyase activity
A7A1_3671	COG2211	Major facilitator Superfamily
A7A1_3674	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A7A1_3676	COG4533	DNA binding
A7A1_3677	COG2814	Major facilitator Superfamily
A7A1_3677	COG0477	Major facilitator Superfamily
A7A1_3678	COG1609	Transcriptional regulator
A7A1_3679	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A7A1_3680	COG0561	phosphatase activity
A7A1_3681	COG0673	inositol 2-dehydrogenase activity
A7A1_3682	COG0738	Major facilitator superfamily
A7A1_3683	COG1846	Transcriptional regulator
A7A1_3684	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7A1_3685	COG0681	Belongs to the peptidase S26 family
A7A1_3686	COG0398	Pfam SNARE associated Golgi protein
A7A1_3689	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A1_3691	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3692	COG4903	ComK protein
A7A1_3694	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3695	COG0723	plastoquinol--plastocyanin reductase activity
A7A1_3695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7A1_3696	COG0840	transmembrane signaling receptor activity
A7A1_3697	COG1268	BioY protein
A7A1_3698	COG0318	PFAM AMP-dependent synthetase and ligase
A7A1_3699	COG0183	Belongs to the thiolase family
A7A1_3700	COG0406	alpha-ribazole phosphatase activity
A7A1_3701	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7A1_3702	COG0604	alcohol dehydrogenase
A7A1_3703	COG0456	acetyltransferase
A7A1_3705	COG0501	Belongs to the peptidase M48B family
A7A1_3707	COG0318	PFAM AMP-dependent synthetase and ligase
A7A1_3708	COG0702	epimerase
A7A1_3709	COG0095	Lipoate-protein ligase
A7A1_3710	COG1234	tRNA 3'-trailer cleavage
A7A1_3712	COG1301	dicarboxylic acid transport
A7A1_3713	COG4405	Protein conserved in bacteria
A7A1_3714	COG1363	Peptidase, m42
A7A1_3716	COG4377	Putative membrane peptidase family (DUF2324)
A7A1_3717	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A1_3718	COG1511	domain protein
A7A1_3719	COG1309	transcriptional regulator
A7A1_3723	COG4473	ABC transporter
A7A1_3724	COG1131	(ABC) transporter
A7A1_3725	COG0537	adenosine 5'-monophosphoramidase activity
A7A1_3726	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A7A1_3728	COG4980	gas vesicle protein
A7A1_3729	COG1846	Transcriptional regulator
A7A1_3733	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7A1_3735	COG3481	metal-dependent phosphohydrolase, HD sub domain
A7A1_3736	COG4717	serine-type aminopeptidase activity
A7A1_3737	COG0420	3'-5' exonuclease activity
A7A1_3738	COG1668	transmembrane transport
A7A1_3739	COG4152	abc transporter atp-binding protein
A7A1_3740	COG1024	Enoyl-CoA hydratase
A7A1_3742	COG0490	domain, Protein
A7A1_3743	COG0475	glutathione-regulated potassium exporter activity
A7A1_3744	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7A1_3745	COG0561	phosphatase activity
A7A1_3747	COG4335	DNA alkylation repair
A7A1_3748	COG3679	Belongs to the UPF0342 family
A7A1_3749	COG4399	Belongs to the UPF0754 family
A7A1_3750	COG0189	ligase activity
A7A1_3751	COG0189	ligase activity
A7A1_3755	COG0702	epimerase
A7A1_3756	COG1132	(ABC) transporter
A7A1_3757	COG1132	(ABC) transporter
A7A1_3758	COG0589	response to stress
A7A1_3759	COG1757	Na H antiporter
A7A1_3760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A1_3761	COG0726	polysaccharide deacetylase
A7A1_3762	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A7A1_3763	COG0668	transmembrane transport
A7A1_3765	COG0584	glycerophosphoryl diester phosphodiesterase
A7A1_3766	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7A1_3767	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7A1_3768	COG1253	flavin adenine dinucleotide binding
A7A1_3770	COG0436	Aminotransferase
A7A1_3771	COG0789	Transcriptional regulator
A7A1_3772	COG1253	flavin adenine dinucleotide binding
A7A1_3773	COG0204	Acyl-transferase
A7A1_3774	COG0667	Aldo Keto reductase
A7A1_3775	COG1595	DNA-templated transcription, initiation
A7A1_3778	COG0456	acetyltransferase
A7A1_3779	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A1_3780	COG0733	neurotransmitter:sodium symporter activity
A7A1_3781	COG0531	amino acid
A7A1_3782	COG1028	Short-chain dehydrogenase reductase Sdr
A7A1_3783	COG0372	Belongs to the citrate synthase family
A7A1_3784	COG0583	DNA-binding transcription factor activity
A7A1_3785	COG1388	LysM domain
A7A1_3785	COG0791	NLP P60 protein
A7A1_3786	COG1785	Belongs to the alkaline phosphatase family
A7A1_3787	COG2719	SpoVR family
A7A1_3788	COG0668	transmembrane transport
A7A1_3789	COG1959	2 iron, 2 sulfur cluster binding
A7A1_3790	COG1388	LysM domain
A7A1_3790	COG0791	NLP P60 protein
A7A1_3793	COG0431	NADPH-dependent FMN reductase
A7A1_3794	COG2197	response regulator
A7A1_3795	COG2203	Gaf domain
A7A1_3795	COG4585	Histidine kinase
A7A1_3796	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7A1_3797	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A7A1_3798	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A7A1_3799	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7A1_3800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A7A1_3801	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7A1_3802	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7A1_3802	COG3153	acetyltransferase
A7A1_3803	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7A1_3804	COG0517	IMP dehydrogenase activity
A7A1_3806	COG0564	pseudouridine synthase activity
A7A1_3807	COG3764	Sortase (surface protein transpeptidase)
A7A1_3808	COG1525	nuclease
A7A1_3808	COG4085	toxin activity
A7A1_3808	COG0737	Belongs to the 5'-nucleotidase family
A7A1_3809	COG5577	PFAM Coat F domain
A7A1_3814	COG1823	symporter activity
A7A1_3815	COG3706	GGDEF domain
A7A1_3816	COG1464	Belongs to the NlpA lipoprotein family
A7A1_3817	COG1278	Cold shock
A7A1_3818	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A7A1_3819	COG1131	(ABC) transporter
A7A1_3820	COG1131	(ABC) transporter
A7A1_3821	COG1725	Transcriptional regulator
A7A1_3824	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7A1_3825	COG2814	Major facilitator Superfamily
A7A1_3826	COG1566	PFAM secretion protein HlyD family protein
A7A1_3827	COG1846	Transcriptional regulator
A7A1_3828	COG2718	Belongs to the UPF0229 family
A7A1_3829	COG2766	serine protein kinase
A7A1_3830	COG1664	Polymer-forming cytoskeletal
A7A1_3831	COG1664	Polymer-forming cytoskeletal
A7A1_3832	COG0789	Transcriptional regulator
A7A1_3833	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A7A1_3835	COG3382	B3 4 domain protein
A7A1_3836	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7A1_3838	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A7A1_3840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A1_3841	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7A1_3842	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7A1_3843	COG1116	anion transmembrane transporter activity
A7A1_3844	COG0753	catalase activity
A7A1_3846	COG0277	FAD linked oxidase domain protein
A7A1_3847	COG0012	GTP binding
A7A1_3859	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A7A1_3862	COG5444	nuclease activity
A7A1_3871	COG2723	6-phospho-beta-galactosidase activity
A7A1_3882	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A7A1_3886	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A7A1_3889	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A1_3890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A1_3893	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A1_3894	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A7A1_3897	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A7A1_3901	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A7A1_3904	COG0316	Belongs to the HesB IscA family
A7A1_3914	COG2124	cytochrome p450
A7A1_3915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A7A1_3916	COG2124	cytochrome p450
A7A1_3924	COG2723	6-phospho-beta-galactosidase activity
A7A1_3928	COG2723	6-phospho-beta-galactosidase activity
A7A1_3929	COG2723	6-phospho-beta-galactosidase activity
A7A1_3932	COG2723	6-phospho-beta-galactosidase activity
A7A1_3935	COG2273	Hydrolase Family 16
A7A1_3943	COG0281	malic enzyme
A7A1_3944	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A7A1_3946	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain