locus-tag	class	description
Q433_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Q433_00010	COG0592	DNA-directed DNA polymerase activity
Q433_00015	COG2501	S4 domain
Q433_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Q433_00030	COG0187	DNA topoisomerase II activity
Q433_00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Q433_00080	COG1686	Belongs to the peptidase S11 family
Q433_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Q433_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Q433_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Q433_00105	COG1428	Deoxynucleoside kinase
Q433_00110	COG1428	Deoxynucleoside kinase
Q433_00115	COG3858	chitin binding
Q433_00115	COG1388	LysM domain
Q433_00120	COG1335	isochorismatase
Q433_00125	COG0590	tRNA wobble adenosine to inosine editing
Q433_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Q433_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Q433_00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Q433_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
Q433_00195	COG3853	Toxic anion resistance protein (TelA)
Q433_00200	COG1982	Orn Lys Arg decarboxylase major
Q433_00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Q433_00210	COG3870	Protein conserved in bacteria
Q433_00215	COG1728	Protein conserved in bacteria
Q433_00220	COG0470	DNA polymerase III
Q433_00225	COG1774	PSP1 C-terminal conserved region
Q433_00230	COG4467	Involved in initiation control of chromosome replication
Q433_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Q433_00240	COG2827	Endonuclease containing a URI domain
Q433_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Q433_00250	COG2002	toxin-antitoxin pair type II binding
Q433_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_00265	COG0084	hydrolase, TatD family'
Q433_00270	COG3583	domain protein
Q433_00270	COG3584	3D domain protein
Q433_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Q433_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Q433_00290	COG4466	Protein conserved in bacteria
Q433_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Q433_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q433_00310	COG0251	oxidation-reduction process
Q433_00315	COG2088	sporulation resulting in formation of a cellular spore
Q433_00325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Q433_00330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Q433_00335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Q433_00340	COG0193	aminoacyl-tRNA hydrolase activity
Q433_00350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Q433_00355	COG2002	toxin-antitoxin pair type II binding
Q433_00360	COG2244	polysaccharide biosynthetic process
Q433_00365	COG3956	TIGRFAM MazG family protein
Q433_00370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Q433_00385	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Q433_00390	COG1098	S1 RNA binding domain
Q433_00405	COG2208	phosphoserine phosphatase activity
Q433_00410	COG2304	oxidoreductase activity
Q433_00415	COG0515	serine threonine protein kinase
Q433_00420	COG0037	tRNA processing
Q433_00430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q433_00435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Q433_00440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Q433_00445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Q433_00450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q433_00455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Q433_00460	COG0512	Glutamine amidotransferase of anthranilate synthase
Q433_00465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_00470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Q433_00475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Q433_00480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Q433_00490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Q433_00495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Q433_00585	COG4463	regulation of RNA biosynthetic process
Q433_00590	COG3880	PFAM UvrB UvrC protein
Q433_00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Q433_00600	COG0542	response to heat
Q433_00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Q433_00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Q433_00615	COG4956	integral membrane protein (PIN domain superfamily)
Q433_00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Q433_00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Q433_00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Q433_00640	COG1045	serine acetyltransferase
Q433_00645	COG0215	cysteine-tRNA ligase activity
Q433_00650	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Q433_00655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q433_00660	COG3688	RNA-binding protein containing a PIN domain
Q433_00665	COG1595	DNA-templated transcription, initiation
Q433_00670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Q433_00675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Q433_00680	COG0250	Participates in transcription elongation, termination and antitermination
Q433_00685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Q433_00690	COG0081	regulation of translation
Q433_00695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Q433_00700	COG0222	ribosome binding
Q433_00705	COG2813	Specifically methylates the guanine in position
Q433_00710	COG0085	RNA polymerase activity
Q433_00715	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Q433_00725	COG1358	cellular component organization or biogenesis
Q433_00730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Q433_00735	COG0049	tRNA binding
Q433_00740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Q433_00745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Q433_00750	COG0596	Alpha beta hydrolase
Q433_00760	COG0051	transcription antitermination factor activity, RNA binding
Q433_00765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Q433_00770	COG0088	Forms part of the polypeptide exit tunnel
Q433_00775	COG0089	rRNA binding
Q433_00780	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Q433_00785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Q433_00790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Q433_00795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Q433_00800	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Q433_00805	COG0255	Belongs to the universal ribosomal protein uL29 family
Q433_00810	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Q433_00815	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Q433_00825	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Q433_00835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Q433_00840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Q433_00845	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Q433_00850	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Q433_00855	COG1841	ribosomal large subunit assembly
Q433_00860	COG0200	Binds to the 23S rRNA
Q433_00865	COG0201	protein transport
Q433_00870	COG0563	adenylate kinase activity
Q433_00875	COG0024	Methionine aminopeptidase
Q433_00885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Q433_00890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Q433_00895	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Q433_00900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Q433_00905	COG0202	RNA polymerase activity
Q433_00910	COG0203	ribosomal protein L17
Q433_00915	COG1122	ATPase activity
Q433_00920	COG1122	ATPase activity
Q433_00925	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Q433_00930	COG0101	tRNA pseudouridine synthase activity
Q433_00935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Q433_00940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q433_00945	COG2226	methyltransferase
Q433_00955	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_00975	COG2194	sulfuric ester hydrolase activity
Q433_00980	COG0726	polysaccharide deacetylase
Q433_01010	COG0659	secondary active sulfate transmembrane transporter activity
Q433_01015	COG0385	Bile acid
Q433_01020	COG2819	hydrolase of the alpha beta superfamily
Q433_01025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_01035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_01040	COG2207	Transcriptional regulator
Q433_01050	COG3876	Protein conserved in bacteria
Q433_01055	COG1472	Belongs to the glycosyl hydrolase 3 family
Q433_01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q433_01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_01065	COG1263	PTS System
Q433_01070	COG1737	Transcriptional regulator
Q433_01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Q433_01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_01085	COG1683	Conserved Protein
Q433_01115	COG1595	DNA-templated transcription, initiation
Q433_01120	COG5662	AntiSigma factor
Q433_01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Q433_01130	COG4856	YbbR-like protein
Q433_01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q433_01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Q433_01155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Q433_01160	COG2169	Transcriptional regulator
Q433_01165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Q433_01170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Q433_01175	COG3002	Belongs to the UPF0753 family
Q433_01180	COG0288	reversible hydration of carbon dioxide
Q433_01190	COG5609	conserved protein (DUF2294)
Q433_01205	COG0640	Transcriptional regulator
Q433_01215	COG2814	Major facilitator Superfamily
Q433_01230	COG1404	Belongs to the peptidase S8 family
Q433_01255	COG1132	(ABC) transporter
Q433_01260	COG0596	Alpha beta hydrolase
Q433_01265	COG0745	RESPONSE REGULATOR receiver
Q433_01270	COG0642	Histidine kinase
Q433_01280	COG0515	serine threonine protein kinase
Q433_01295	COG1113	amino acid transport
Q433_01310	COG2602	Beta-lactamase
Q433_01315	COG2124	cytochrome p450
Q433_01325	COG0531	amino acid
Q433_01330	COG0584	glycerophosphoryl diester phosphodiesterase
Q433_01335	COG2271	Major facilitator Superfamily
Q433_01350	COG0456	acetyltransferase
Q433_01350	COG1846	Transcriptional regulator
Q433_01355	COG2271	Major facilitator Superfamily
Q433_01365	COG3409	Peptidoglycan-binding domain 1 protein
Q433_01370	COG0697	spore germination
Q433_01375	COG2207	Transcriptional regulator
Q433_01375	COG1917	Cupin 2, conserved barrel domain protein
Q433_01380	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Q433_01385	COG3591	Belongs to the peptidase S1B family
Q433_01395	COG0596	Alpha beta hydrolase
Q433_01400	COG1183	phosphatidylcholine synthase activity
Q433_01405	COG0586	Pfam SNARE associated Golgi protein
Q433_01410	COG0688	phosphatidylethanolamine metabolic process
Q433_01430	COG1301	dicarboxylic acid transport
Q433_01435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_01435	COG2190	(PTS) system
Q433_01435	COG1263	PTS System
Q433_01440	COG0363	glucosamine-6-phosphate deaminase activity
Q433_01460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_01465	COG0833	amino acid
Q433_01470	COG2040	homocysteine
Q433_01480	COG1115	amino acid carrier protein
Q433_01485	COG2066	Belongs to the glutaminase family
Q433_01490	COG4191	Histidine kinase
Q433_01495	COG0784	Response regulator, receiver
Q433_01500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q433_01505	COG1012	belongs to the aldehyde dehydrogenase family
Q433_01510	COG2271	Major facilitator Superfamily
Q433_01515	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_01520	COG2186	Transcriptional regulator
Q433_01525	COG2721	sulfolactate sulfo-lyase activity
Q433_01540	COG3173	Aminoglycoside phosphotransferase
Q433_01550	COG0697	spore germination
Q433_01555	COG0745	RESPONSE REGULATOR receiver
Q433_01560	COG2205	protein histidine kinase activity
Q433_01565	COG1131	(ABC) transporter
Q433_01590	COG3773	Cell wall hydrolase
Q433_01595	COG2304	oxidoreductase activity
Q433_01605	COG3540	Alkaline phosphatase
Q433_01610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q433_01615	COG0805	protein transport
Q433_01620	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Q433_01625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q433_01630	COG0477	Major facilitator Superfamily
Q433_01635	COG1309	transcriptional regulator
Q433_01645	COG0252	asparaginase activity
Q433_01650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Q433_01655	COG1714	RDD family
Q433_01660	COG1405	negative regulation of cell septum assembly
Q433_01660	COG3012	SEC-C Motif Domain Protein
Q433_01665	COG3290	protein histidine kinase activity
Q433_01670	COG3279	Response regulator of the LytR AlgR family
Q433_01675	COG4555	ABC transporter
Q433_01680	COG1668	transmembrane transport
Q433_01685	COG0667	Aldo Keto reductase
Q433_01695	COG1595	DNA-templated transcription, initiation
Q433_01710	COG1876	peptidase activity
Q433_01715	COG0457	Tetratricopeptide repeat
Q433_01720	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_01725	COG0366	Alpha amylase catalytic
Q433_01730	COG0803	Belongs to the bacterial solute-binding protein 9 family
Q433_01735	COG1121	(ABC) transporter
Q433_01740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q433_01745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_01750	COG2310	stress, protein
Q433_01755	COG2310	stress, protein
Q433_01760	COG2310	stress, protein
Q433_01765	COG0861	Integral membrane protein TerC family
Q433_01775	COG3853	Toxic anion resistance protein (TelA)
Q433_01780	COG0477	Major facilitator Superfamily
Q433_01785	COG2814	Major facilitator Superfamily
Q433_01790	COG0640	Transcriptional regulator
Q433_01800	COG4175	Glycine betaine
Q433_01800	COG0517	IMP dehydrogenase activity
Q433_01805	COG4176	ABC-type proline glycine betaine transport system permease component
Q433_01810	COG2113	Glycine betaine
Q433_01815	COG1473	amidohydrolase
Q433_01820	COG1288	antiporter activity
Q433_01835	COG0366	Alpha amylase catalytic
Q433_01845	COG0039	L-malate dehydrogenase activity
Q433_01850	COG1620	l-lactate permease
Q433_01855	COG2814	Major facilitator Superfamily
Q433_01860	COG1846	Transcriptional regulator
Q433_01865	COG1280	lysine exporter protein (LysE YggA)
Q433_01870	COG3403	YqcI/YcgG family
Q433_01875	COG1113	amino acid transport
Q433_01880	COG3665	Urea carboxylase-associated protein
Q433_01885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Q433_01890	COG1660	Displays ATPase and GTPase activities
Q433_01900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Q433_01905	COG2226	methyltransferase
Q433_01910	COG0583	DNA-binding transcription factor activity
Q433_01915	COG3458	cephalosporin-C deacetylase activity
Q433_01920	COG3541	Predicted nucleotidyltransferase
Q433_01925	COG0506	proline dehydrogenase activity
Q433_01930	COG1012	belongs to the aldehyde dehydrogenase family
Q433_01935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_01940	COG2508	Transcriptional regulator
Q433_01945	COG3689	TIGRFAM TIGR03943 family protein
Q433_01950	COG0701	Predicted permease
Q433_01955	COG2267	carboxylic ester hydrolase activity
Q433_01960	COG0492	ferredoxin-NADP+ reductase activity
Q433_01965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Q433_01965	COG1587	Uroporphyrinogen-III synthase
Q433_01970	COG2146	nitrite reductase [NAD(P)H] activity
Q433_01975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q433_01980	COG0243	molybdopterin cofactor binding
Q433_01985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q433_01990	COG2223	nitrite transmembrane transporter activity
Q433_01995	COG1469	GTP cyclohydrolase I activity
Q433_02000	COG1376	ErfK ybiS ycfS ynhG family protein
Q433_02010	COG0523	cobalamin synthesis protein
Q433_02015	COG0765	amino acid transport
Q433_02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_02035	COG1714	RDD family
Q433_02045	COG2723	6-phospho-beta-galactosidase activity
Q433_02055	COG3209	COG3209 Rhs family protein
Q433_02060	COG0840	transmembrane signaling receptor activity
Q433_02060	COG3290	protein histidine kinase activity
Q433_02065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Q433_02070	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Q433_02075	COG1733	regulation of RNA biosynthetic process
Q433_02085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_02090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_02100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Q433_02105	COG2814	Major facilitator Superfamily
Q433_02115	COG0697	spore germination
Q433_02135	COG2364	Membrane
Q433_02145	COG1126	abc transporter atp-binding protein
Q433_02150	COG0765	amino acid transport
Q433_02155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_02160	COG0583	DNA-binding transcription factor activity
Q433_02165	COG0163	prenyltransferase activity
Q433_02170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Q433_02185	COG0596	Alpha beta hydrolase
Q433_02190	COG3104	oligopeptide transport
Q433_02195	COG5434	Belongs to the glycosyl hydrolase 28 family
Q433_02205	COG0697	spore germination
Q433_02215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Q433_02220	COG1136	(ABC) transporter
Q433_02225	COG0577	efflux transmembrane transporter activity
Q433_02230	COG0745	RESPONSE REGULATOR receiver
Q433_02235	COG3850	Histidine kinase
Q433_02235	COG5002	protein histidine kinase activity
Q433_02240	COG0457	Tetratricopeptide repeat
Q433_02260	COG0527	aspartate kinase activity
Q433_02270	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_02275	COG4605	iron ion homeostasis
Q433_02280	COG4604	ABC transporter, ATP-binding protein
Q433_02285	COG4607	ABC-type enterochelin transport system periplasmic component
Q433_02290	COG2814	Major facilitator Superfamily
Q433_02295	COG1309	transcriptional regulator
Q433_02300	COG0778	Nitroreductase
Q433_02305	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Q433_02310	COG0640	Transcriptional regulator
Q433_02315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_02320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Q433_02325	COG1012	belongs to the aldehyde dehydrogenase family
Q433_02330	COG4975	Glucose uptake
Q433_02335	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_02340	COG4549	nuclear export factor GLE1
Q433_02345	COG2372	response to copper ion
Q433_02345	COG1276	copper resistance
Q433_02350	COG1349	DNA-binding transcription factor activity
Q433_02360	COG2213	PTS system mannitol-specific
Q433_02365	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_02370	COG0246	Mannitol dehydrogenase
Q433_02375	COG0473	3-isopropylmalate dehydrogenase activity
Q433_02380	COG0681	Belongs to the peptidase S26 family
Q433_02385	COG0412	Dienelactone hydrolase
Q433_02390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q433_02400	COG0561	phosphatase activity
Q433_02405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Q433_02410	COG1914	H( )-stimulated, divalent metal cation uptake system
Q433_02420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Q433_02425	COG1984	allophanate hydrolase subunit 2
Q433_02430	COG1414	Transcriptional regulator
Q433_02435	COG2755	lipolytic protein G-D-S-L family
Q433_02445	COG2329	Antibiotic biosynthesis monooxygenase
Q433_02455	COG0768	penicillin binding
Q433_02460	COG4989	oxidoreductase activity
Q433_02465	COG3711	transcriptional antiterminator
Q433_02475	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_02480	COG2226	methyltransferase
Q433_02485	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_02490	COG1917	Cupin 2, conserved barrel domain protein
Q433_02495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_02500	COG3871	stress protein (general stress protein 26)
Q433_02510	COG2814	Major facilitator Superfamily
Q433_02515	COG1522	sequence-specific DNA binding
Q433_02520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Q433_02520	COG0551	DNA topoisomerase type I activity
Q433_02525	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Q433_02530	COG3706	GGDEF domain
Q433_02535	COG5298	Protein conserved in bacteria
Q433_02540	COG1215	transferase activity, transferring glycosyl groups
Q433_02550	COG0531	amino acid
Q433_02555	COG0494	nUDIX hydrolase
Q433_02560	COG0028	Belongs to the TPP enzyme family
Q433_02575	COG1914	H( )-stimulated, divalent metal cation uptake system
Q433_02585	COG2261	transglycosylase associated protein
Q433_02590	COG4876	unkown
Q433_02595	COG2217	Heavy metal translocating P-type atpase
Q433_02600	COG3729	General stress protein
Q433_02605	COG0662	Cupin 2, conserved barrel domain protein
Q433_02610	COG2329	Antibiotic biosynthesis monooxygenase
Q433_02615	COG3546	catalase activity
Q433_02620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Q433_02625	COG3290	protein histidine kinase activity
Q433_02630	COG4565	transcriptional regulatory protein
Q433_02635	COG1301	dicarboxylic acid transport
Q433_02640	COG0628	permease
Q433_02650	COG1131	(ABC) transporter
Q433_02655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Q433_02665	COG1960	acyl-CoA dehydrogenase activity
Q433_02680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q433_02685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_02690	COG1181	Belongs to the D-alanine--D-alanine ligase family
Q433_02695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Q433_02705	COG0513	Belongs to the DEAD box helicase family
Q433_02710	COG3402	PFAM membrane-flanked domain
Q433_02715	COG3428	Bacterial PH domain
Q433_02720	COG0705	Rhomboid family
Q433_02725	COG0736	holo-[acyl-carrier-protein] synthase activity
Q433_02730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Q433_02735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Q433_02740	COG0864	Transcriptional regulator
Q433_02745	COG2337	Toxic component of a toxin-antitoxin (TA) module
Q433_02750	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_02755	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_02760	COG2172	sigma factor antagonist activity
Q433_02765	COG2208	phosphoserine phosphatase activity
Q433_02770	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_02775	COG2172	sigma factor antagonist activity
Q433_02780	COG1191	sigma factor activity
Q433_02785	COG2208	phosphoserine phosphatase activity
Q433_02790	COG2183	response to ionizing radiation
Q433_02800	COG3091	SprT-like family
Q433_02840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_02855	COG1476	TRANSCRIPTIONal
Q433_02885	COG0693	protein deglycase activity
Q433_02890	COG1278	Cold shock
Q433_02905	COG0697	spore germination
Q433_02910	COG1917	Cupin 2, conserved barrel domain protein
Q433_02910	COG2207	Transcriptional regulator
Q433_02915	COG0697	spore germination
Q433_02925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_02930	COG0477	Major facilitator Superfamily
Q433_02940	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
Q433_02960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_02965	COG1309	transcriptional regulator
Q433_02970	COG0697	spore germination
Q433_02975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_02980	COG2030	dehydratase
Q433_02985	COG3545	Serine hydrolase
Q433_02990	COG1733	regulation of RNA biosynthetic process
Q433_02995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_03000	COG2814	Major facilitator Superfamily
Q433_03005	COG1309	transcriptional regulator
Q433_03015	COG0640	Transcriptional regulator
Q433_03020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Q433_03030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_03035	COG0697	spore germination
Q433_03040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_03045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Q433_03050	COG0640	Transcriptional regulator
Q433_03055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q433_03075	COG4585	Histidine kinase
Q433_03080	COG2197	response regulator
Q433_03085	COG2409	Drug exporters of the RND superfamily
Q433_03095	COG0596	Alpha beta hydrolase
Q433_03100	COG1811	Na channel or pump
Q433_03105	COG4978	Transcriptional regulator
Q433_03105	COG0789	Transcriptional regulator
Q433_03110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q433_03115	COG0778	Nitroreductase
Q433_03120	COG0346	lactoylglutathione lyase activity
Q433_03125	COG2259	Doxx family
Q433_03130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_03155	COG2323	membrane
Q433_03160	COG2323	membrane
Q433_03165	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_03180	COG1309	transcriptional regulator
Q433_03190	COG0456	acetyltransferase
Q433_03200	COG1113	amino acid transport
Q433_03210	COG2318	DinB family
Q433_03215	COG1846	Transcriptional regulator
Q433_03220	COG1033	growth of symbiont in host cell
Q433_03220	COG2409	Drug exporters of the RND superfamily
Q433_03225	COG0778	Nitroreductase
Q433_03230	COG1846	Transcriptional regulator
Q433_03240	COG2814	Major facilitator Superfamily
Q433_03245	COG0730	response to heat
Q433_03250	COG1802	Transcriptional regulator
Q433_03255	COG3858	chitin binding
Q433_03255	COG1388	LysM domain
Q433_03260	COG1819	glycosyl
Q433_03270	COG1785	Belongs to the alkaline phosphatase family
Q433_03275	COG5646	InterPro IPR014922
Q433_03285	COG0454	-acetyltransferase
Q433_03290	COG1078	dGTPase activity
Q433_03300	COG1388	LysM domain
Q433_03305	COG2814	Major facilitator Superfamily
Q433_03310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_03315	COG1447	Phosphotransferase system cellobiose-specific component IIA
Q433_03320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_03325	COG2723	6-phospho-beta-galactosidase activity
Q433_03330	COG2188	Transcriptional regulator
Q433_03335	COG1940	carbohydrate kinase activity
Q433_03340	COG1482	cell wall glycoprotein biosynthetic process
Q433_03345	COG4124	Belongs to the glycosyl hydrolase 26 family
Q433_03390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Q433_03395	COG0802	atpase or kinase
Q433_03400	COG1214	PFAM Peptidase M22, glycoprotease
Q433_03405	COG0456	acetyltransferase
Q433_03410	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Q433_03420	COG0488	(ABC) transporter
Q433_03425	COG0315	cyclic pyranopterin monophosphate synthase activity
Q433_03430	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Q433_03435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q433_03440	COG0805	protein transport
Q433_03450	COG1266	CAAX protease self-immunity
Q433_03455	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Q433_03460	COG0459	protein refolding
Q433_03465	COG1073	alpha beta
Q433_03470	COG0457	Tetratricopeptide repeat
Q433_03475	COG1063	alcohol dehydrogenase
Q433_03480	COG2211	Major facilitator Superfamily
Q433_03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_03490	COG1842	Phage shock protein A
Q433_03495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Q433_03500	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Q433_03505	COG4260	virion core protein, lumpy skin disease virus
Q433_03520	COG2814	Major facilitator Superfamily
Q433_03525	COG1063	alcohol dehydrogenase
Q433_03530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Q433_03535	COG0823	Involved in the tonB-independent uptake of proteins
Q433_03550	COG2267	carboxylic ester hydrolase activity
Q433_03560	COG2132	Multicopper oxidase
Q433_03565	COG1113	amino acid transport
Q433_03575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Q433_03580	COG0714	Associated with various cellular activities
Q433_03585	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
Q433_03590	COG1305	Transglutaminase-like
Q433_03600	COG0519	Catalyzes the synthesis of GMP from XMP
Q433_03600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Q433_03605	COG2252	PERMEase
Q433_03620	COG3064	Membrane
Q433_03630	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Q433_03645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Q433_03650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Q433_03655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Q433_03660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Q433_03665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Q433_03670	COG0047	phosphoribosylformylglycinamidine synthase activity
Q433_03675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Q433_03680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Q433_03685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Q433_03690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Q433_03695	COG0138	bifunctional purine biosynthesis protein purh
Q433_03700	COG0151	Belongs to the GarS family
Q433_03705	COG1522	sequence-specific DNA binding
Q433_03710	COG0531	amino acid
Q433_03720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Q433_03725	COG1470	cell adhesion involved in biofilm formation
Q433_03730	COG4496	protein, YerC YecD
Q433_03735	COG0069	glutamate synthase activity
Q433_03745	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Q433_03750	COG0210	DNA helicase
Q433_03755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Q433_03760	COG4851	CamS sex pheromone cAM373 precursor
Q433_03765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_03770	COG1285	pathogenesis
Q433_03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_03780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q433_03785	COG0154	amidase activity
Q433_03790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Q433_03795	COG1309	transcriptional regulator
Q433_03800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Q433_03805	COG1597	lipid kinase activity
Q433_03810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Q433_03820	COG0457	Tetratricopeptide repeat
Q433_03835	COG5444	nuclease activity
Q433_03840	COG3391	amine dehydrogenase activity
Q433_03845	COG0457	Tetratricopeptide repeat
Q433_03855	COG0217	transcriptional regulatory protein
Q433_03865	COG1309	transcriptional regulator
Q433_03870	COG3631	Ketosteroid isomerase-related protein
Q433_03875	COG0702	epimerase
Q433_03895	COG3546	catalase activity
Q433_03900	COG0454	-acetyltransferase
Q433_03915	COG5578	integral membrane protein
Q433_03920	COG2972	Histidine kinase
Q433_03925	COG4753	response regulator
Q433_03925	COG2207	Transcriptional regulator
Q433_03930	COG1653	transport
Q433_03935	COG1175	transmembrane transport
Q433_03940	COG0395	ABC-type sugar transport system, permease component
Q433_03945	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Q433_03950	COG2207	Transcriptional regulator
Q433_03955	COG2755	lipolytic protein G-D-S-L family
Q433_03965	COG5578	integral membrane protein
Q433_03970	COG3401	FG-GAP repeat protein
Q433_03975	COG3401	FG-GAP repeat protein
Q433_03980	COG2755	lipolytic protein G-D-S-L family
Q433_03985	COG1874	Beta-galactosidase
Q433_03995	COG1653	transport
Q433_04000	COG4209	transmembrane transport
Q433_04005	COG0395	ABC-type sugar transport system, permease component
Q433_04010	COG1486	melibiose metabolic process
Q433_04015	COG2323	membrane
Q433_04020	COG2329	Antibiotic biosynthesis monooxygenase
Q433_04025	COG0346	lactoylglutathione lyase activity
Q433_04045	COG0670	Belongs to the BI1 family
Q433_04050	COG0697	spore germination
Q433_04055	COG1846	Transcriptional regulator
Q433_04060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q433_04075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q433_04075	COG2124	cytochrome p450
Q433_04085	COG1368	sulfuric ester hydrolase activity
Q433_04095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Q433_04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_04105	COG1442	glycosyl transferase family 8
Q433_04110	COG1216	Glycosyl transferase, family 2
Q433_04115	COG1442	glycosyl transferase family 8
Q433_04120	COG2223	nitrite transmembrane transporter activity
Q433_04130	COG1011	Hydrolase
Q433_04135	COG0531	amino acid
Q433_04140	COG1012	belongs to the aldehyde dehydrogenase family
Q433_04145	COG0840	transmembrane signaling receptor activity
Q433_04150	COG0488	(ABC) transporter
Q433_04160	COG0789	Transcriptional regulator
Q433_04165	COG2814	Major facilitator Superfamily
Q433_04185	COG0488	(ABC) transporter
Q433_04195	COG0513	Belongs to the DEAD box helicase family
Q433_04200	COG0456	acetyltransferase
Q433_04205	COG2130	NADP-dependent
Q433_04220	COG2211	Major facilitator Superfamily
Q433_04225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Q433_04235	COG1120	ATPase activity
Q433_04240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_04245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_04250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Q433_04265	COG3866	Pectate lyase
Q433_04270	COG0471	metal ion transport
Q433_04275	COG3290	protein histidine kinase activity
Q433_04280	COG4565	transcriptional regulatory protein
Q433_04285	COG3181	Tripartite tricarboxylate transporter family receptor
Q433_04295	COG2851	Citrate transporter
Q433_04300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_04305	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Q433_04310	COG1254	Belongs to the acylphosphatase family
Q433_04315	COG2258	MOSC domain
Q433_04335	COG0024	Methionine aminopeptidase
Q433_04340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_04340	COG1263	PTS System
Q433_04345	COG1368	sulfuric ester hydrolase activity
Q433_04360	COG1115	amino acid carrier protein
Q433_04365	COG0531	amino acid
Q433_04390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_04390	COG1263	PTS System
Q433_04395	COG0366	Alpha amylase catalytic
Q433_04400	COG2188	Transcriptional regulator
Q433_04405	COG0778	Nitroreductase
Q433_04410	COG0737	Belongs to the 5'-nucleotidase family
Q433_04420	COG0693	protein deglycase activity
Q433_04425	COG2814	Major facilitator Superfamily
Q433_04430	COG4840	Belongs to the UPF0435 family
Q433_04440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q433_04445	COG4980	gas vesicle protein
Q433_04450	COG1295	ribonuclease BN
Q433_04460	COG0477	Major facilitator Superfamily
Q433_04470	COG0387	Pfam Sodium calcium exchanger
Q433_04480	COG0668	transmembrane transport
Q433_04485	COG0535	radical SAM domain protein
Q433_04495	COG0726	polysaccharide deacetylase
Q433_04500	COG2084	Dehydrogenase
Q433_04505	COG0598	Magnesium transport protein CorA
Q433_04510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Q433_04515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Q433_04525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Q433_04530	COG4637	Psort location Cytoplasmic, score
Q433_04545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Q433_04550	COG0022	dehydrogenase e1 component
Q433_04555	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_04560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q433_04565	COG3284	Transcriptional regulator
Q433_04575	COG1742	UPF0060 membrane protein
Q433_04595	COG4842	Belongs to the WXG100 family
Q433_04600	COG1486	melibiose metabolic process
Q433_04605	COG1737	Transcriptional regulator
Q433_04610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_04610	COG1263	PTS System
Q433_04615	COG5434	Belongs to the glycosyl hydrolase 28 family
Q433_04620	COG1132	(ABC) transporter
Q433_04625	COG1132	(ABC) transporter
Q433_04630	COG2259	Doxx family
Q433_04635	COG2514	catechol 2,3-dioxygenase activity
Q433_04640	COG4585	Histidine kinase
Q433_04645	COG2197	response regulator
Q433_04655	COG1131	(ABC) transporter
Q433_04660	COG1511	domain protein
Q433_04660	COG0842	Transport permease protein
Q433_04665	COG0842	Transport permease protein
Q433_04670	COG1695	Transcriptional regulator
Q433_04680	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Q433_04685	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
Q433_04690	COG2318	DinB family
Q433_04695	COG2814	Major facilitator Superfamily
Q433_04700	COG1846	Transcriptional regulator
Q433_04705	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Q433_04705	COG0392	lysyltransferase activity
Q433_04710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_04715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_04720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_04725	COG0384	phenazine biosynthesis protein PhzF
Q433_04730	COG0778	Nitroreductase
Q433_04745	COG1090	epimerase
Q433_04750	COG2137	regulation of response to DNA damage stimulus
Q433_04765	COG2814	Major facilitator Superfamily
Q433_04780	COG3103	Sh3 type 3 domain protein
Q433_04790	COG0596	Alpha beta hydrolase
Q433_04800	COG0463	Glycosyl transferase, family 2
Q433_04805	COG4485	Bacterial membrane protein, YfhO
Q433_04810	COG1988	membrane-bound metal-dependent
Q433_04815	COG1194	a g-specific adenine glycosylase
Q433_04825	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_04840	COG3557	Belongs to the UPF0374 family
Q433_04845	COG1132	(ABC) transporter
Q433_04850	COG4129	membrane
Q433_04855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Q433_04860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Q433_04865	COG0735	belongs to the Fur family
Q433_04980	COG4326	sporulation control protein
Q433_04990	COG5577	PFAM Coat F domain
Q433_04995	COG3340	Belongs to the peptidase S51 family
Q433_05000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Q433_05005	COG0277	FAD linked oxidase domain protein
Q433_05015	COG0753	catalase activity
Q433_05025	COG1116	anion transmembrane transporter activity
Q433_05030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Q433_05035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q433_05040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_05050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Q433_05060	COG1476	TRANSCRIPTIONal
Q433_05070	COG3382	B3 4 domain protein
Q433_05075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Q433_05085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Q433_05090	COG0789	Transcriptional regulator
Q433_05095	COG1664	Polymer-forming cytoskeletal
Q433_05100	COG1664	Polymer-forming cytoskeletal
Q433_05110	COG2766	serine protein kinase
Q433_05115	COG2718	Belongs to the UPF0229 family
Q433_05125	COG1846	Transcriptional regulator
Q433_05130	COG1566	PFAM secretion protein HlyD family protein
Q433_05135	COG2814	Major facilitator Superfamily
Q433_05140	COG0655	NAD(P)H dehydrogenase (quinone) activity
Q433_05160	COG1725	Transcriptional regulator
Q433_05165	COG1131	(ABC) transporter
Q433_05170	COG1131	(ABC) transporter
Q433_05175	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Q433_05180	COG1278	Cold shock
Q433_05190	COG1464	Belongs to the NlpA lipoprotein family
Q433_05195	COG3706	GGDEF domain
Q433_05200	COG1823	symporter activity
Q433_05220	COG5577	PFAM Coat F domain
Q433_05225	COG0737	Belongs to the 5'-nucleotidase family
Q433_05225	COG1525	nuclease
Q433_05225	COG4085	toxin activity
Q433_05230	COG3764	Sortase (surface protein transpeptidase)
Q433_05235	COG0564	pseudouridine synthase activity
Q433_05245	COG0517	IMP dehydrogenase activity
Q433_05250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q433_05255	COG3153	acetyltransferase
Q433_05255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q433_05265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q433_05270	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Q433_05275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Q433_05280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Q433_05285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Q433_05290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Q433_05295	COG2203	Gaf domain
Q433_05295	COG4585	Histidine kinase
Q433_05300	COG2197	response regulator
Q433_05305	COG0431	NADPH-dependent FMN reductase
Q433_05320	COG0791	NLP P60 protein
Q433_05320	COG1388	LysM domain
Q433_05325	COG1959	2 iron, 2 sulfur cluster binding
Q433_05330	COG0668	transmembrane transport
Q433_05335	COG2719	SpoVR family
Q433_05340	COG1785	Belongs to the alkaline phosphatase family
Q433_05345	COG1388	LysM domain
Q433_05345	COG0791	NLP P60 protein
Q433_05350	COG0583	DNA-binding transcription factor activity
Q433_05355	COG0372	Belongs to the citrate synthase family
Q433_05360	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_05365	COG0531	amino acid
Q433_05370	COG0733	neurotransmitter:sodium symporter activity
Q433_05375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_05395	COG1595	DNA-templated transcription, initiation
Q433_05400	COG0667	Aldo Keto reductase
Q433_05405	COG0204	Acyl-transferase
Q433_05410	COG1253	flavin adenine dinucleotide binding
Q433_05415	COG0789	Transcriptional regulator
Q433_05420	COG0436	Aminotransferase
Q433_05430	COG1253	flavin adenine dinucleotide binding
Q433_05435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Q433_05440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Q433_05445	COG0584	glycerophosphoryl diester phosphodiesterase
Q433_05455	COG0668	transmembrane transport
Q433_05460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Q433_05465	COG0726	polysaccharide deacetylase
Q433_05470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_05475	COG1757	Na H antiporter
Q433_05480	COG0589	response to stress
Q433_05495	COG1132	(ABC) transporter
Q433_05500	COG1132	(ABC) transporter
Q433_05505	COG0702	epimerase
Q433_05525	COG0189	ligase activity
Q433_05530	COG0189	ligase activity
Q433_05535	COG4399	Belongs to the UPF0754 family
Q433_05540	COG3679	Belongs to the UPF0342 family
Q433_05545	COG4335	DNA alkylation repair
Q433_05550	COG0561	phosphatase activity
Q433_05555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q433_05560	COG0475	glutathione-regulated potassium exporter activity
Q433_05565	COG0490	domain, Protein
Q433_05575	COG1024	Enoyl-CoA hydratase
Q433_05585	COG4152	abc transporter atp-binding protein
Q433_05590	COG1668	transmembrane transport
Q433_05595	COG0420	3'-5' exonuclease activity
Q433_05600	COG4717	serine-type aminopeptidase activity
Q433_05605	COG3481	metal-dependent phosphohydrolase, HD sub domain
Q433_05615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Q433_05650	COG1846	Transcriptional regulator
Q433_05655	COG4980	gas vesicle protein
Q433_05670	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Q433_05675	COG0537	adenosine 5'-monophosphoramidase activity
Q433_05685	COG1131	(ABC) transporter
Q433_05690	COG4473	ABC transporter
Q433_05700	COG1473	amidohydrolase
Q433_05705	COG3069	C4-dicarboxylate transmembrane transporter activity
Q433_05715	COG2329	Antibiotic biosynthesis monooxygenase
Q433_05720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_05725	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Q433_05745	COG1309	transcriptional regulator
Q433_05750	COG1511	domain protein
Q433_05755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q433_05760	COG4377	Putative membrane peptidase family (DUF2324)
Q433_05775	COG1363	Peptidase, m42
Q433_05780	COG4405	Protein conserved in bacteria
Q433_05785	COG1301	dicarboxylic acid transport
Q433_05795	COG1234	tRNA 3'-trailer cleavage
Q433_05800	COG0095	Lipoate-protein ligase
Q433_05805	COG0702	epimerase
Q433_05810	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_05820	COG0501	Belongs to the peptidase M48B family
Q433_05825	COG1404	Belongs to the peptidase S8 family
Q433_05840	COG0604	alcohol dehydrogenase
Q433_05850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Q433_05855	COG0406	alpha-ribazole phosphatase activity
Q433_05860	COG0183	Belongs to the thiolase family
Q433_05865	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_05870	COG1268	BioY protein
Q433_05875	COG0840	transmembrane signaling receptor activity
Q433_05885	COG0723	plastoquinol--plastocyanin reductase activity
Q433_05885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q433_05890	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_05900	COG4903	ComK protein
Q433_05905	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_05920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_05935	COG0398	Pfam SNARE associated Golgi protein
Q433_05940	COG0681	Belongs to the peptidase S26 family
Q433_05945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Q433_05950	COG1846	Transcriptional regulator
Q433_05955	COG0738	Major facilitator superfamily
Q433_05960	COG0673	inositol 2-dehydrogenase activity
Q433_05965	COG0561	phosphatase activity
Q433_05970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q433_05975	COG1609	Transcriptional regulator
Q433_05980	COG3180	Ammonia monooxygenase
Q433_05985	COG2814	Major facilitator Superfamily
Q433_05985	COG0477	Major facilitator Superfamily
Q433_05990	COG4533	DNA binding
Q433_06000	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Q433_06005	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Q433_06010	COG1074	ATP-dependent DNA helicase activity
Q433_06015	COG0420	3'-5' exonuclease activity
Q433_06020	COG0419	ATPase involved in DNA repair
Q433_06025	COG1403	HNH endonuclease
Q433_06070	COG5337	Spore coat protein CotH
Q433_06080	COG0179	Fumarylacetoacetate (FAA) hydrolase
Q433_06090	COG1404	Belongs to the peptidase S8 family
Q433_06100	COG0367	asparagine synthase
Q433_06105	COG2318	DinB family
Q433_06110	COG1562	ergosterol biosynthetic process
Q433_06115	COG0534	Mate efflux family protein
Q433_06120	COG2207	Transcriptional regulator
Q433_06120	COG1917	Cupin 2, conserved barrel domain protein
Q433_06125	COG1609	Transcriptional regulator
Q433_06135	COG0673	inositol 2-dehydrogenase activity
Q433_06140	COG2318	DinB family
Q433_06145	COG1279	arginine transmembrane transporter activity
Q433_06150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Q433_06155	COG1357	PFAM Pentapeptide repeats (8 copies)
Q433_06160	COG2267	carboxylic ester hydrolase activity
Q433_06165	COG0529	Catalyzes the synthesis of activated sulfate
Q433_06170	COG2046	Belongs to the sulfate adenylyltransferase family
Q433_06175	COG0175	sulfate reduction
Q433_06180	COG2045	Belongs to the ComB family
Q433_06185	COG1809	phosphosulfolactate synthase activity
Q433_06190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_06195	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_06200	COG2814	Major facilitator Superfamily
Q433_06205	COG0454	-acetyltransferase
Q433_06210	COG2153	protein acetylation
Q433_06215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Q433_06215	COG0646	methionine synthase
Q433_06225	COG1666	GTP binding
Q433_06230	COG2996	Protein conserved in bacteria
Q433_06250	COG1695	Transcriptional regulator
Q433_06265	COG3227	Zinc metalloprotease (Elastase)
Q433_06270	COG1307	EDD domain protein, DegV family
Q433_06275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_06295	COG0561	phosphatase activity
Q433_06300	COG1073	alpha beta
Q433_06305	COG2151	metal-sulfur cluster biosynthetic enzyme
Q433_06315	COG0277	FAD linked oxidase domain protein
Q433_06320	COG2271	Major facilitator Superfamily
Q433_06325	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Q433_06340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q433_06345	COG0505	Belongs to the CarA family
Q433_06350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Q433_06355	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Q433_06370	COG2267	carboxylic ester hydrolase activity
Q433_06385	COG1744	ABC transporter substrate-binding protein PnrA-like
Q433_06400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q433_06405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q433_06410	COG5504	Zn-dependent protease
Q433_06415	COG0444	Belongs to the ABC transporter superfamily
Q433_06420	COG4608	Belongs to the ABC transporter superfamily
Q433_06430	COG0601	transmembrane transport
Q433_06435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q433_06445	COG0180	Tryptophanyl-tRNA synthetase
Q433_06455	COG4166	transmembrane transport
Q433_06460	COG0601	transmembrane transport
Q433_06465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q433_06470	COG0444	Belongs to the ABC transporter superfamily
Q433_06475	COG4608	Belongs to the ABC transporter superfamily
Q433_06480	COG2814	Major facilitator Superfamily
Q433_06485	COG0456	acetyltransferase
Q433_06490	COG1393	Belongs to the ArsC family
Q433_06495	COG0861	Integral membrane protein TerC family
Q433_06500	COG4862	establishment of competence for transformation
Q433_06510	COG4469	Competence protein
Q433_06515	COG1164	Oligoendopeptidase f
Q433_06535	COG2346	COG2346, Truncated hemoglobins
Q433_06540	COG0741	lytic transglycosylase activity
Q433_06545	COG4116	CYTH
Q433_06555	COG2357	RelA SpoT domain protein
Q433_06560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Q433_06565	COG0564	pseudouridine synthase activity
Q433_06570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Q433_06580	COG0475	glutathione-regulated potassium exporter activity
Q433_06580	COG0569	domain protein
Q433_06585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Q433_06590	COG0352	thiamine-phosphate diphosphorylase activity
Q433_06595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q433_06600	COG2104	thiamine diphosphate biosynthetic process
Q433_06605	COG2022	thiamine diphosphate biosynthetic process
Q433_06610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Q433_06615	COG0351	phosphomethylpyrimidine kinase
Q433_06620	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Q433_06685	COG0210	DNA helicase
Q433_06695	COG2153	protein acetylation
Q433_06700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Q433_06705	COG2382	esterase
Q433_06715	COG0626	cystathionine gamma-synthase activity
Q433_06720	COG0626	cystathionine gamma-synthase activity
Q433_06730	COG5505	Protein of unknown function (DUF819)
Q433_06815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Q433_06820	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_06830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_06830	COG3711	transcriptional antiterminator
Q433_06835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_06835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_06835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_06840	COG1482	cell wall glycoprotein biosynthetic process
Q433_06850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_06860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Q433_06880	COG0109	protoheme IX farnesyltransferase activity
Q433_06890	COG0726	polysaccharide deacetylase
Q433_06910	COG5504	Zn-dependent protease
Q433_06915	COG2205	protein histidine kinase activity
Q433_06925	COG3383	formate dehydrogenase (NAD+) activity
Q433_06930	COG2427	Protein of unknown function (DUF1641)
Q433_06940	COG1051	belongs to the nudix hydrolase family
Q433_06950	COG2124	cytochrome p450
Q433_06955	COG1819	glycosyl
Q433_06965	COG1587	Uroporphyrinogen-III synthase
Q433_06970	COG0390	transport system, permease component
Q433_06975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q433_06980	COG0697	spore germination
Q433_06990	COG4297	protein containing double-stranded beta helix domain
Q433_07005	COG1252	NADH dehydrogenase
Q433_07015	COG1904	glucuronate isomerase
Q433_07020	COG2211	Major facilitator Superfamily
Q433_07025	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Q433_07030	COG1063	alcohol dehydrogenase
Q433_07035	COG1312	Catalyzes the dehydration of D-mannonate
Q433_07040	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_07045	COG2271	Major facilitator Superfamily
Q433_07050	COG1609	Transcriptional regulator
Q433_07055	COG0246	Mannitol dehydrogenase
Q433_07060	COG2721	sulfolactate sulfo-lyase activity
Q433_07065	COG0730	response to heat
Q433_07070	COG2318	DinB family
Q433_07075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Q433_07080	COG0457	Tetratricopeptide repeat
Q433_07090	COG2350	Protein conserved in bacteria
Q433_07095	COG1388	LysM domain
Q433_07095	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_07095	COG3409	Peptidoglycan-binding domain 1 protein
Q433_07105	COG4195	phage-related replication protein
Q433_07110	COG3546	catalase activity
Q433_07115	COG2856	Zn peptidase
Q433_07120	COG1396	sequence-specific DNA binding
Q433_07130	COG1522	sequence-specific DNA binding
Q433_07135	COG1484	DNA-dependent DNA replication
Q433_07160	COG1595	DNA-templated transcription, initiation
Q433_07165	COG5484	DNA packaging
Q433_07165	COG3728	DNA packaging
Q433_07170	COG1783	phage Terminase large subunit
Q433_07175	COG5518	Phage portal protein
Q433_07180	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Q433_07185	COG4653	Phage capsid family
Q433_07235	COG3953	SLT domain
Q433_07235	COG5412	phage tail tape measure protein
Q433_07235	COG5412	phage tail tape measure protein
Q433_07235	COG3953	SLT domain
Q433_07240	COG1652	LysM domain
Q433_07245	COG4193	domain, Protein
Q433_07255	COG3628	GPW Gp25 family protein
Q433_07260	COG3299	homolog of phage Mu protein gp47
Q433_07265	COG3778	Protein conserved in bacteria
Q433_07305	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_07305	COG3409	Peptidoglycan-binding domain 1 protein
Q433_07325	COG0306	phosphate transporter
Q433_07330	COG1392	Phosphate transport regulator
Q433_07335	COG0531	amino acid
Q433_07345	COG0346	lactoylglutathione lyase activity
Q433_07355	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Q433_07360	COG0463	Glycosyl transferase, family 2
Q433_07375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q433_07380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_07385	COG2362	D-Aminopeptidase
Q433_07390	COG0601	transmembrane transport
Q433_07395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Q433_07400	COG0444	Belongs to the ABC transporter superfamily
Q433_07405	COG4166	transmembrane transport
Q433_07415	COG1619	proteins homologs of microcin C7 resistance protein MccF
Q433_07420	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_07425	COG0791	NLP P60 protein
Q433_07430	COG4608	Belongs to the ABC transporter superfamily
Q433_07435	COG2706	6-phosphogluconolactonase activity
Q433_07440	COG1834	amidinotransferase
Q433_07445	COG1607	acyl-coa hydrolase
Q433_07450	COG1017	nitric oxide dioxygenase activity
Q433_07450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Q433_07460	COG2323	membrane
Q433_07465	COG2318	DinB family
Q433_07470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_07475	COG2076	Multidrug Resistance protein
Q433_07480	COG2076	Multidrug Resistance protein
Q433_07485	COG0788	formyltetrahydrofolate deformylase activity
Q433_07490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Q433_07495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Q433_07505	COG1764	response to oxidative stress
Q433_07510	COG1846	Transcriptional regulator
Q433_07515	COG1764	response to oxidative stress
Q433_07525	COG0590	tRNA wobble adenosine to inosine editing
Q433_07530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Q433_07540	COG1404	Belongs to the peptidase S8 family
Q433_07545	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_07550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Q433_07555	COG1122	ATPase activity
Q433_07560	COG4721	ABC-type cobalt transport system, permease component
Q433_07570	COG0745	RESPONSE REGULATOR receiver
Q433_07575	COG5002	protein histidine kinase activity
Q433_07575	COG3850	Histidine kinase
Q433_07580	COG3212	peptidase
Q433_07585	COG3212	peptidase
Q433_07610	COG2239	Acts as a magnesium transporter
Q433_07615	COG0789	Transcriptional regulator
Q433_07630	COG1846	Transcriptional regulator
Q433_07640	COG0726	polysaccharide deacetylase
Q433_07645	COG1408	metallophosphoesterase
Q433_07655	COG0463	Glycosyl transferase, family 2
Q433_07660	COG3285	dna ligase
Q433_07660	COG1793	dna ligase
Q433_07665	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Q433_07670	COG3300	MHYT domain
Q433_07670	COG5001	Diguanylate cyclase
Q433_07675	COG0586	Pfam SNARE associated Golgi protein
Q433_07685	COG0861	Integral membrane protein TerC family
Q433_07690	COG1191	sigma factor activity
Q433_07710	COG0501	Belongs to the peptidase M48B family
Q433_07715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Q433_07730	COG3594	Acyltransferase
Q433_07735	COG5002	protein histidine kinase activity
Q433_07740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Q433_07750	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Q433_07755	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Q433_07760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Q433_07765	COG0436	Aminotransferase
Q433_07770	COG1850	ribulose-bisphosphate carboxylase activity
Q433_07775	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
Q433_07780	COG0235	Class ii aldolase
Q433_07785	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Q433_07790	COG3339	Conserved Protein
Q433_07805	COG3852	Histidine kinase
Q433_07815	COG1846	Transcriptional regulator
Q433_07820	COG1360	Flagellar Motor Protein
Q433_07825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Q433_07835	COG0542	response to heat
Q433_07840	COG3949	Membrane
Q433_07845	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Q433_07850	COG0720	synthase
Q433_07855	COG0602	queuosine metabolic process
Q433_07860	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Q433_07870	COG1733	regulation of RNA biosynthetic process
Q433_07875	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_07880	COG1388	LysM domain
Q433_07880	COG4641	Protein conserved in bacteria
Q433_07885	COG1388	LysM domain
Q433_07890	COG3858	chitin binding
Q433_07910	COG4873	Protein conserved in bacteria
Q433_07925	COG3773	Cell wall hydrolase
Q433_07930	COG2244	polysaccharide biosynthetic process
Q433_07935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_07940	COG2217	Heavy metal translocating P-type atpase
Q433_07950	COG0006	proline dipeptidase activity
Q433_07960	COG1609	Transcriptional regulator
Q433_07965	COG3711	transcriptional antiterminator
Q433_07975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_07975	COG2190	(PTS) system
Q433_07975	COG1263	PTS System
Q433_07980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_07985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Q433_07995	COG1533	DNA photolyase activity
Q433_08000	COG0456	acetyltransferase
Q433_08005	COG0840	transmembrane signaling receptor activity
Q433_08010	COG2084	Dehydrogenase
Q433_08015	COG2340	Cysteine-rich secretory protein family
Q433_08020	COG0768	penicillin binding
Q433_08025	COG4191	Histidine kinase
Q433_08030	COG0436	Aminotransferase
Q433_08040	COG0784	Response regulator, receiver
Q433_08040	COG0835	chemotaxis
Q433_08050	COG2814	Major facilitator Superfamily
Q433_08055	COG1376	ErfK ybiS ycfS ynhG family protein
Q433_08060	COG1408	metallophosphoesterase
Q433_08065	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_08070	COG2200	EAL domain
Q433_08085	COG4703	Protein of unknown function (DUF1797)
Q433_08090	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Q433_08100	COG0517	IMP dehydrogenase activity
Q433_08105	COG0583	DNA-binding transcription factor activity
Q433_08110	COG0716	FMN binding
Q433_08120	COG0716	FMN binding
Q433_08125	COG2171	N-acyltransferase activity
Q433_08130	COG1473	amidohydrolase
Q433_08140	COG0668	transmembrane transport
Q433_08145	COG0450	alkyl hydroperoxide reductase
Q433_08150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_08170	COG0746	molybdenum cofactor guanylyltransferase activity
Q433_08185	COG0303	'Molybdopterin
Q433_08190	COG1763	Mo-molybdopterin cofactor biosynthetic process
Q433_08195	COG0314	molybdopterin synthase activity
Q433_08200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Q433_08205	COG1132	(ABC) transporter
Q433_08210	COG1132	(ABC) transporter
Q433_08220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q433_08225	COG1136	(ABC) transporter
Q433_08230	COG0577	efflux transmembrane transporter activity
Q433_08235	COG1349	DNA-binding transcription factor activity
Q433_08240	COG1105	Belongs to the carbohydrate kinase PfkB family
Q433_08245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_08245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Q433_08245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_08250	COG0681	Belongs to the peptidase S26 family
Q433_08260	COG0488	(ABC) transporter
Q433_08265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Q433_08270	COG2309	aminopeptidase activity
Q433_08280	COG1077	Cell shape determining protein MreB Mrl
Q433_08290	COG2002	toxin-antitoxin pair type II binding
Q433_08295	COG3852	Histidine kinase
Q433_08300	COG2105	PFAM AIG2 family protein
Q433_08300	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Q433_08305	COG0569	domain protein
Q433_08310	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Q433_08315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Q433_08330	COG0561	phosphatase activity
Q433_08335	COG0242	peptide deformylase activity
Q433_08345	COG0497	DNA recombination
Q433_08350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Q433_08355	COG0022	dehydrogenase e1 component
Q433_08360	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_08365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q433_08370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_08385	COG1982	Orn Lys Arg decarboxylase major
Q433_08390	COG4476	Belongs to the UPF0223 family
Q433_08395	COG4493	Belongs to the UPF0637 family
Q433_08410	COG0483	inositol monophosphate 1-phosphatase activity
Q433_08420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Q433_08440	COG1595	DNA-templated transcription, initiation
Q433_08470	COG4896	Protein conserved in bacteria
Q433_08480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Q433_08485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Q433_08490	COG2066	Belongs to the glutaminase family
Q433_08495	COG4838	Belongs to the UPF0358 family
Q433_08500	COG0772	Belongs to the SEDS family
Q433_08505	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Q433_08515	COG1612	heme a metabolic process
Q433_08525	COG0109	protoheme IX farnesyltransferase activity
Q433_08535	COG2010	Cytochrome c
Q433_08535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Q433_08540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q433_08545	COG1845	cytochrome c oxidase, subunit III
Q433_08550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Q433_08555	COG3336	cytochrome c oxidase
Q433_08565	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Q433_08570	COG2340	Cysteine-rich secretory protein family
Q433_08585	COG3679	Belongs to the UPF0342 family
Q433_08590	COG4471	UPF0298 protein
Q433_08605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Q433_08610	COG3314	Sporulation integral membrane protein YlbJ
Q433_08615	COG1752	Esterase of the alpha-beta hydrolase superfamily
Q433_08620	COG3480	Lon protease (S16) C-terminal proteolytic domain
Q433_08625	COG1323	Belongs to the UPF0348 family
Q433_08635	COG1399	metal-binding, possibly nucleic acid-binding protein
Q433_08640	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Q433_08655	COG0454	-acetyltransferase
Q433_08660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Q433_08665	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Q433_08670	COG2001	Belongs to the MraZ family
Q433_08675	COG0275	rRNA processing
Q433_08680	COG4839	cell division protein FtsL
Q433_08695	COG0768	penicillin binding
Q433_08705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Q433_08715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q433_08720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Q433_08725	COG0772	Belongs to the SEDS family
Q433_08730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q433_08735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Q433_08740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Q433_08745	COG3879	Bacterial protein of unknown function (DUF881)
Q433_08750	COG3879	Bacterial protein of unknown function (DUF881)
Q433_08755	COG3856	small basic protein
Q433_08760	COG0849	cell division
Q433_08765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Q433_08775	COG4412	M6 family metalloprotease domain protein
Q433_08775	COG1404	Belongs to the peptidase S8 family
Q433_08785	COG1191	sigma factor activity
Q433_08790	COG1191	sigma factor activity
Q433_08795	COG1119	ATPase activity
Q433_08800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_08805	COG1873	PFAM PRC-barrel domain
Q433_08820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Q433_08825	COG1799	cell septum assembly
Q433_08830	COG0762	integral membrane protein
Q433_08835	COG2302	S4 RNA-binding domain
Q433_08840	COG3599	regulation of cell shape
Q433_08855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Q433_08860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Q433_08865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Q433_08870	COG0564	pseudouridine synthase activity
Q433_08880	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Q433_08885	COG2233	PERMEase
Q433_08890	COG0540	Belongs to the ATCase OTCase family
Q433_08895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Q433_08900	COG0505	Belongs to the CarA family
Q433_08905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Q433_08910	COG0543	2 iron, 2 sulfur cluster binding
Q433_08915	COG0167	dihydroorotate dehydrogenase activity
Q433_08920	COG0284	orotidine-5'-phosphate decarboxylase activity
Q433_08925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Q433_08940	COG0175	sulfate reduction
Q433_08945	COG0306	phosphate transporter
Q433_08950	COG2046	Belongs to the sulfate adenylyltransferase family
Q433_08955	COG0529	Catalyzes the synthesis of activated sulfate
Q433_08960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Q433_08965	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
Q433_08970	COG1648	precorrin-2 dehydrogenase activity
Q433_08980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Q433_08985	COG1561	YicC-like family, N-terminal region
Q433_08990	COG2052	Domain of unknown function (DUF370)
Q433_08995	COG0194	GDP metabolic process
Q433_09000	COG1758	RNA polymerase activity
Q433_09005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Q433_09010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Q433_09015	COG0242	peptide deformylase activity
Q433_09020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Q433_09025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Q433_09025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q433_09030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Q433_09035	COG0631	protein serine/threonine phosphatase activity
Q433_09040	COG0515	serine threonine protein kinase
Q433_09040	COG2815	serine threonine protein kinase
Q433_09045	COG1162	GTPase activity
Q433_09050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Q433_09055	COG1564	THIamine pyrophosphokinase
Q433_09065	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Q433_09070	COG1302	Protein conserved in bacteria
Q433_09075	COG1461	Dihydroxyacetone kinase
Q433_09080	COG1760	l-serine dehydratase
Q433_09085	COG1760	l-serine dehydratase
Q433_09090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Q433_09095	COG1349	DNA-binding transcription factor activity
Q433_09095	COG2050	protein possibly involved in aromatic compounds catabolism
Q433_09100	COG0416	fatty acid biosynthetic process
Q433_09105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q433_09110	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_09115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_09120	COG0571	ribonuclease III activity
Q433_09125	COG1196	nuclear chromosome segregation
Q433_09130	COG0552	protein localization to endoplasmic reticulum
Q433_09140	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Q433_09145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Q433_09150	COG0228	four-way junction DNA binding
Q433_09155	COG1837	Belongs to the UPF0109 family
Q433_09165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Q433_09170	COG0336	Belongs to the RNA methyltransferase TrmD family
Q433_09175	COG0335	large ribosomal subunit rRNA binding
Q433_09180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Q433_09185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Q433_09195	COG2257	FlhB HrpN YscU SpaS Family
Q433_09200	COG0045	succinate-CoA ligase (ADP-forming) activity
Q433_09205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Q433_09210	COG0758	DNA mediated transformation
Q433_09215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Q433_09220	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Q433_09225	COG4974	Belongs to the 'phage' integrase family
Q433_09230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Q433_09235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Q433_09240	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Q433_09245	COG1815	bacterial-type flagellum-dependent cell motility
Q433_09250	COG1558	bacterial-type flagellum-dependent cell motility
Q433_09255	COG1677	Flagellar hook-basal body complex protein FliE
Q433_09260	COG1766	The M ring may be actively involved in energy transduction
Q433_09265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q433_09270	COG1317	bacterial-type flagellum organization
Q433_09275	COG1157	protein secretion by the type III secretion system
Q433_09280	COG2882	bacterial-type flagellum organization
Q433_09285	COG3334	PFAM MgtE intracellular
Q433_09290	COG3144	bacterial-type flagellum assembly
Q433_09295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Q433_09300	COG4786	Flagellar basal body rod
Q433_09305	COG1582	Flagellar protein (FlbD)
Q433_09310	COG1580	Controls the rotational direction of flagella during chemotaxis
Q433_09315	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q433_09320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Q433_09320	COG1776	CheC inhibitor of MCP methylation
Q433_09325	COG2201	protein-glutamate methylesterase activity
Q433_09330	COG3190	flagellar
Q433_09335	COG1338	Plays a role in the flagellum-specific transport system
Q433_09340	COG1987	bacterial-type flagellum assembly
Q433_09345	COG1684	flagellar biosynthetic protein fliR
Q433_09350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q433_09355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Q433_09360	COG1419	protein localization to endoplasmic reticulum
Q433_09365	COG0455	bacterial-type flagellum organization
Q433_09370	COG2201	protein-glutamate methylesterase activity
Q433_09375	COG2198	Histidine kinase
Q433_09375	COG0643	Histidine kinase
Q433_09380	COG0835	chemotaxis
Q433_09385	COG1776	CheC inhibitor of MCP methylation
Q433_09390	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Q433_09395	COG1191	sigma factor activity
Q433_09405	COG0052	Belongs to the universal ribosomal protein uS2 family
Q433_09410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Q433_09415	COG0528	UMP kinase activity
Q433_09420	COG0233	cytoplasmic translational termination
Q433_09425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Q433_09430	COG4589	Belongs to the CDS family
Q433_09435	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Q433_09440	COG0750	zinc metalloprotease
Q433_09445	COG0442	prolyl-tRNA aminoacylation
Q433_09450	COG2176	DNA-directed DNA polymerase activity
Q433_09455	COG0779	Required for maturation of 30S ribosomal subunits
Q433_09460	COG0195	Participates in both transcription termination and antitermination
Q433_09465	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Q433_09470	COG1358	cellular component organization or biogenesis
Q433_09475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Q433_09480	COG1550	Protein conserved in bacteria
Q433_09485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Q433_09490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Q433_09495	COG0196	riboflavin kinase activity
Q433_09500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Q433_09505	COG1185	polyribonucleotide nucleotidyltransferase activity
Q433_09510	COG0726	polysaccharide deacetylase
Q433_09515	COG0612	Peptidase, M16
Q433_09520	COG1873	PFAM PRC-barrel domain
Q433_09530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Q433_09535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Q433_09540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Q433_09545	COG0527	aspartate kinase activity
Q433_09550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Q433_09555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Q433_09560	COG0740	serine-type endopeptidase activity
Q433_09570	COG4980	gas vesicle protein
Q433_09570	COG1674	ftsk spoiiie
Q433_09575	COG2188	Transcriptional regulator
Q433_09585	COG2814	Major facilitator Superfamily
Q433_09590	COG0612	Peptidase, M16
Q433_09595	COG0612	Peptidase, M16
Q433_09600	COG0300	oxidoreductase activity
Q433_09615	COG1426	Protein conserved in bacteria
Q433_09620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Q433_09625	COG1058	Belongs to the CinA family
Q433_09625	COG1546	Belongs to the CinA family
Q433_09630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Q433_09635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q433_09640	COG1418	mRNA catabolic process
Q433_09645	COG1692	metallophosphoesterase
Q433_09650	COG2359	stage V sporulation protein S
Q433_09655	COG1063	alcohol dehydrogenase
Q433_09660	COG0156	8-amino-7-oxononanoate synthase activity
Q433_09665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q433_09670	COG4550	Control of competence regulator ComK, YlbF/YmcA
Q433_09680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Q433_09685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Q433_09710	COG3226	Transcriptional regulator
Q433_09715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_09725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q433_09735	COG3321	synthase
Q433_09740	COG2070	2-Nitropropane dioxygenase
Q433_09740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Q433_09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_09750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Q433_09755	COG3425	synthase
Q433_09760	COG1024	Enoyl-CoA hydratase
Q433_09765	COG1024	Enoyl-CoA hydratase
Q433_09770	COG3321	synthase
Q433_09770	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_09770	COG0300	oxidoreductase activity
Q433_09770	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_09770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_09775	COG4221	oxidoreductase activity
Q433_09775	COG3321	synthase
Q433_09775	COG0300	oxidoreductase activity
Q433_09775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_09780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_09780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_09780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_09780	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_09780	COG3321	synthase
Q433_09785	COG4221	oxidoreductase activity
Q433_09785	COG3321	synthase
Q433_09785	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_09785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_09790	COG3321	synthase
Q433_09790	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Q433_09790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Q433_09790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_09795	COG2124	cytochrome p450
Q433_09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_09810	COG1404	Belongs to the peptidase S8 family
Q433_09825	COG4195	phage-related replication protein
Q433_09830	COG1764	response to oxidative stress
Q433_09835	COG2076	Multidrug Resistance protein
Q433_09840	COG2076	Multidrug Resistance protein
Q433_09855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Q433_09860	COG1923	regulation of RNA biosynthetic process
Q433_09875	COG1780	Probably involved in ribonucleotide reductase function
Q433_09880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Q433_09885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Q433_09890	COG4112	unkown
Q433_09895	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_09910	COG0464	growth
Q433_09920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Q433_09925	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Q433_09930	COG0789	Transcriptional regulator
Q433_09935	COG0174	glutamine synthetase
Q433_09940	COG4974	Belongs to the 'phage' integrase family
Q433_09950	COG3172	ATPase kinase involved in NAD metabolism
Q433_09950	COG1056	cytidyltransferase-related domain
Q433_10050	COG0582	viral genome integration into host DNA
Q433_10060	COG1598	PFAM Uncharacterised protein family UPF0150
Q433_10160	COG5280	Phage tail tape measure protein TP901
Q433_10160	COG3953	SLT domain
Q433_10170	COG1705	Flagellar rod assembly protein muramidase FlgJ
Q433_10210	COG4824	toxin secretion phage lysis holin
Q433_10215	COG3409	Peptidoglycan-binding domain 1 protein
Q433_10215	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_10215	COG1388	LysM domain
Q433_10285	COG0463	Glycosyl transferase, family 2
Q433_10305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_10325	COG3655	Transcriptional regulator
Q433_10345	COG0135	phosphoribosylanthranilate isomerase activity
Q433_10360	COG2211	Major facilitator Superfamily
Q433_10365	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_10370	COG1940	carbohydrate kinase activity
Q433_10375	COG2115	Belongs to the xylose isomerase family
Q433_10380	COG1070	Carbohydrate kinase
Q433_10390	COG1525	nuclease
Q433_10395	COG2814	Major facilitator Superfamily
Q433_10400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Q433_10410	COG0756	dUTP diphosphatase activity
Q433_10455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Q433_10470	COG3832	glyoxalase III activity
Q433_10490	COG0697	spore germination
Q433_10525	COG4195	phage-related replication protein
Q433_10535	COG0346	lactoylglutathione lyase activity
Q433_10550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Q433_10555	COG1388	LysM domain
Q433_10560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Q433_10565	COG4224	UPF0291 protein
Q433_10570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Q433_10585	COG3763	UPF0154 protein
Q433_10595	COG0785	Cytochrome C biogenesis protein
Q433_10600	COG2201	protein-glutamate methylesterase activity
Q433_10605	COG4846	Membrane protein involved in cytochrome C biogenesis
Q433_10615	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_10630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Q433_10635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_10655	COG0824	Thioesterase
Q433_10665	COG4841	protein insertion into membrane
Q433_10670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Q433_10680	COG1832	CoA-binding protein
Q433_10685	COG0187	DNA topoisomerase II activity
Q433_10690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Q433_10710	COG1115	amino acid carrier protein
Q433_10725	COG5520	Belongs to the glycosyl hydrolase 30 family
Q433_10730	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_10740	COG2246	polysaccharide biosynthetic process
Q433_10745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Q433_10750	COG0586	Pfam SNARE associated Golgi protein
Q433_10755	COG2404	hydrolase activity, acting on ester bonds
Q433_10760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Q433_10765	COG1024	Enoyl-CoA hydratase
Q433_10770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q433_10775	COG0511	ligase activity, forming carbon-carbon bonds
Q433_10780	COG0439	Biotin carboxylase
Q433_10785	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_10790	COG1960	acyl-CoA dehydrogenase activity
Q433_10805	COG1649	PFAM Uncharacterised BCR, COG1649
Q433_10815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_10815	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Q433_10820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_10825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_10830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_10835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_10840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_10845	COG2027	D-alanyl-D-alanine carboxypeptidase
Q433_10850	COG2017	converts alpha-aldose to the beta-anomer
Q433_10855	COG0534	Mate efflux family protein
Q433_10870	COG0582	viral genome integration into host DNA
Q433_10875	COG0166	Belongs to the GPI family
Q433_10880	COG0405	Gamma-glutamyltransferase
Q433_10885	COG0583	DNA-binding transcription factor activity
Q433_10890	COG0604	alcohol dehydrogenase
Q433_10895	COG0493	'glutamate synthase
Q433_10900	COG0067	glutamate synthase
Q433_10900	COG0070	glutamate synthase
Q433_10900	COG0069	glutamate synthase activity
Q433_10905	COG0583	DNA-binding transcription factor activity
Q433_10910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Q433_10915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_10930	COG0300	oxidoreductase activity
Q433_10935	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
Q433_10945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Q433_10965	COG2814	Major facilitator Superfamily
Q433_10970	COG1070	Carbohydrate kinase
Q433_10975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q433_10980	COG0243	molybdopterin cofactor binding
Q433_11005	COG5278	phosphoserine phosphatase activity
Q433_11005	COG0840	transmembrane signaling receptor activity
Q433_11010	COG2368	4-hydroxyphenylacetate
Q433_11015	COG4305	rare lipoprotein A
Q433_11020	COG3619	membrane
Q433_11025	COG3866	Pectate lyase
Q433_11030	COG2135	peptidase activity
Q433_11045	COG2140	Oxalate decarboxylase
Q433_11055	COG0456	acetyltransferase
Q433_11075	COG2720	vancomycin resistance protein
Q433_11085	COG3655	Transcriptional regulator
Q433_11090	COG3739	integral membrane protein
Q433_11095	COG0583	DNA-binding transcription factor activity
Q433_11100	COG0697	spore germination
Q433_11110	COG0693	protein deglycase activity
Q433_11120	COG2367	Beta-lactamase
Q433_11140	COG3848	Pyruvate phosphate dikinase
Q433_11140	COG0574	Belongs to the PEP-utilizing enzyme family
Q433_11145	COG0726	polysaccharide deacetylase
Q433_11155	COG2314	TM2 domain
Q433_11160	COG1396	sequence-specific DNA binding
Q433_11290	COG0457	Tetratricopeptide repeat
Q433_11300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Q433_11335	COG4282	regulation of fungal-type cell wall biogenesis
Q433_11340	COG1231	oxidoreductase activity
Q433_11345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_11350	COG2207	Transcriptional regulator
Q433_11350	COG0662	Cupin 2, conserved barrel domain protein
Q433_11355	COG0456	acetyltransferase
Q433_11360	COG1309	transcriptional regulator
Q433_11365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_11370	COG3708	Transcriptional regulator
Q433_11375	COG2378	regulation of single-species biofilm formation
Q433_11385	COG0640	Transcriptional regulator
Q433_11390	COG0741	lytic transglycosylase activity
Q433_11395	COG2322	membrane
Q433_11410	COG1619	proteins homologs of microcin C7 resistance protein MccF
Q433_11415	COG3239	Fatty acid desaturase
Q433_11420	COG4585	Histidine kinase
Q433_11425	COG2197	response regulator
Q433_11435	COG3584	3D domain protein
Q433_11435	COG1388	LysM domain
Q433_11440	COG0514	ATP-dependent DNA helicase (RecQ)
Q433_11455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Q433_11460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Q433_11475	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_11500	COG1012	belongs to the aldehyde dehydrogenase family
Q433_11505	COG1657	PFAM Prenyltransferase squalene oxidase
Q433_11510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q433_11515	COG0733	neurotransmitter:sodium symporter activity
Q433_11520	COG0385	Bile acid
Q433_11525	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_11530	COG0567	Dehydrogenase, E1 component
Q433_11535	COG4548	von Willebrand factor, type A
Q433_11540	COG0714	Associated with various cellular activities
Q433_11545	COG2032	superoxide dismutase activity
Q433_11550	COG1388	LysM domain
Q433_11550	COG0791	NLP P60 protein
Q433_11555	COG1819	glycosyl
Q433_11560	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Q433_11570	COG0534	Mate efflux family protein
Q433_11575	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_11580	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q433_11585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q433_11595	COG2962	Rard protein
Q433_11610	COG2610	gluconate transmembrane transporter activity
Q433_11615	COG1942	4-Oxalocrotonate Tautomerase
Q433_11620	COG1733	regulation of RNA biosynthetic process
Q433_11625	COG0778	Nitroreductase
Q433_11630	COG0400	carboxylic ester hydrolase activity
Q433_11635	COG0346	lactoylglutathione lyase activity
Q433_11645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_11650	COG0793	Belongs to the peptidase S41A family
Q433_11650	COG3409	Peptidoglycan-binding domain 1 protein
Q433_11655	COG2226	methyltransferase
Q433_11665	COG1876	peptidase activity
Q433_11675	COG0813	purine-nucleoside phosphorylase activity
Q433_11695	COG0671	phosphoesterase, PA-phosphatase related
Q433_11715	COG4479	Belongs to the UPF0346 family
Q433_11725	COG1509	lysine 2,3-aminomutase activity
Q433_11735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_11740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Q433_11745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Q433_11750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q433_11765	COG0456	acetyltransferase
Q433_11770	COG0463	Glycosyl transferase, family 2
Q433_11785	COG4641	Protein conserved in bacteria
Q433_11790	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
Q433_11800	COG1086	Polysaccharide biosynthesis protein
Q433_11805	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q433_11810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Q433_11815	COG1846	Transcriptional regulator
Q433_11820	COG0534	Mate efflux family protein
Q433_11830	COG4698	Protein conserved in bacteria
Q433_11835	COG2755	lipolytic protein G-D-S-L family
Q433_11840	COG1999	signal sequence binding
Q433_11850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Q433_11855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Q433_11860	COG1272	protein, Hemolysin III
Q433_11865	COG0204	Acyl-transferase
Q433_11870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q433_11875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Q433_11880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Q433_11895	COG2136	Putative SAM-dependent methyltransferase
Q433_11895	COG2521	methyltransferase
Q433_11905	COG0129	dihydroxy-acid dehydratase activity
Q433_11915	COG1413	lyase activity
Q433_11920	COG1418	mRNA catabolic process
Q433_11925	COG0386	Belongs to the glutathione peroxidase family
Q433_11930	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Q433_11940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Q433_11950	COG1278	Cold shock
Q433_11970	COG0328	RNA-DNA hybrid ribonuclease activity
Q433_11975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Q433_11980	COG0328	RNA-DNA hybrid ribonuclease activity
Q433_11990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q433_12010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Q433_12020	COG1755	Isoprenylcysteine carboxyl methyltransferase
Q433_12025	COG3424	synthase
Q433_12035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q433_12040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Q433_12050	COG0800	Aldolase
Q433_12055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_12060	COG1609	Transcriptional regulator
Q433_12065	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Q433_12070	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_12075	COG1199	ATP-dependent helicase activity
Q433_12090	COG0116	Belongs to the methyltransferase superfamily
Q433_12100	COG4474	Belongs to the UPF0398 family
Q433_12115	COG3359	exonuclease
Q433_12120	COG1111	helicase
Q433_12120	COG1205	dead DEAH box helicase
Q433_12125	COG2190	(PTS) system
Q433_12130	COG0071	Belongs to the small heat shock protein (HSP20) family
Q433_12165	COG3331	DNA recombination
Q433_12170	COG4499	WXG100 protein secretion system (Wss), protein YukC
Q433_12170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_12180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Q433_12185	COG3935	DnaD domain protein
Q433_12190	COG0017	Asparaginyl-tRNA synthetase
Q433_12195	COG0436	Aminotransferase
Q433_12200	COG5353	protein conserved in bacteria
Q433_12210	COG1199	ATP-dependent helicase activity
Q433_12210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Q433_12215	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Q433_12220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Q433_12225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Q433_12230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Q433_12230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Q433_12235	COG0617	tRNA 3'-terminal CCA addition
Q433_12240	COG0438	transferase activity, transferring glycosyl groups
Q433_12245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Q433_12250	COG1803	Methylglyoxal synthase
Q433_12255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Q433_12260	COG1694	Mazg nucleotide pyrophosphohydrolase
Q433_12265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_12275	COG4347	Protein of unknown function (DUF1405)
Q433_12280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Q433_12280	COG2010	Cytochrome c
Q433_12285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Q433_12290	COG0723	plastoquinol--plastocyanin reductase activity
Q433_12300	COG5582	Belongs to the UPF0302 family
Q433_12305	COG0457	Tetratricopeptide repeat
Q433_12315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Q433_12320	COG0287	Prephenate dehydrogenase
Q433_12325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Q433_12335	COG0133	tryptophan synthase activity
Q433_12340	COG0135	phosphoribosylanthranilate isomerase activity
Q433_12350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Q433_12355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Q433_12360	COG4401	Chorismate mutase type I
Q433_12365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Q433_12370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Q433_12375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Q433_12385	COG0105	UTP biosynthetic process
Q433_12390	COG0142	geranyltranstransferase activity
Q433_12395	COG2226	methyltransferase
Q433_12400	COG0142	geranyltranstransferase activity
Q433_12410	COG0302	gtp cyclohydrolase
Q433_12415	COG0776	regulation of translation
Q433_12425	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Q433_12440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Q433_12445	COG1160	GTP binding
Q433_12470	COG1304	FMN binding
Q433_12475	COG0539	negative regulation of cytoplasmic translation
Q433_12480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Q433_12490	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
Q433_12495	COG2959	enzyme of heme biosynthesis
Q433_12500	COG3409	Peptidoglycan-binding domain 1 protein
Q433_12500	COG3773	Cell wall hydrolase
Q433_12510	COG2339	peptidase activity
Q433_12515	COG0492	ferredoxin-NADP+ reductase activity
Q433_12520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q433_12530	COG4862	establishment of competence for transformation
Q433_12535	COG1408	metallophosphoesterase
Q433_12545	COG1388	LysM domain
Q433_12550	COG1266	CAAX protease self-immunity
Q433_12555	COG0514	ATP-dependent DNA helicase (RecQ)
Q433_12560	COG4955	Helix-turn-helix domain
Q433_12565	COG1141	Ferredoxin
Q433_12570	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Q433_12580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Q433_12585	COG0710	3-dehydroquinate dehydratase activity
Q433_12595	COG1595	DNA-templated transcription, initiation
Q433_12600	COG5002	protein histidine kinase activity
Q433_12605	COG0745	RESPONSE REGULATOR receiver
Q433_12610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q433_12615	COG1333	cytochrome c biogenesis protein
Q433_12620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_12630	COG1187	pseudouridine synthase activity
Q433_12635	COG0700	Nucleoside recognition
Q433_12640	COG2715	membrane protein required for spore maturation
Q433_12645	COG1686	Belongs to the peptidase S11 family
Q433_12655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Q433_12660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Q433_12665	COG1547	Domain of unknown function (DUF309)
Q433_12670	COG0456	acetyltransferase
Q433_12675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Q433_12680	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q433_12680	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Q433_12685	COG0307	riboflavin synthase, alpha
Q433_12690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Q433_12690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Q433_12710	COG0681	Belongs to the peptidase S26 family
Q433_12725	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
Q433_12745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Q433_12755	COG4086	secreted protein
Q433_12760	COG0019	diaminopimelate decarboxylase activity
Q433_12765	COG0697	spore germination
Q433_12780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Q433_12800	COG1191	sigma factor activity
Q433_12805	COG2172	sigma factor antagonist activity
Q433_12810	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_12815	COG1686	Belongs to the peptidase S11 family
Q433_12825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Q433_12830	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Q433_12835	COG4974	Belongs to the 'phage' integrase family
Q433_12850	COG0735	belongs to the Fur family
Q433_12855	COG1300	Membrane
Q433_12865	COG0281	malic enzyme
Q433_12870	COG1757	Na H antiporter
Q433_12875	COG1027	Aspartate ammonia-lyase
Q433_12880	COG0252	asparaginase activity
Q433_12885	COG1396	sequence-specific DNA binding
Q433_12890	COG1379	DNA repair
Q433_12895	COG0494	nUDIX hydrolase
Q433_12905	COG0667	Aldo Keto reductase
Q433_12920	COG1073	alpha beta
Q433_12930	COG4918	Iron-sulphur cluster biosynthesis
Q433_12935	COG0456	acetyltransferase
Q433_12935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Q433_12940	COG2329	Antibiotic biosynthesis monooxygenase
Q433_12945	COG0456	acetyltransferase
Q433_12955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Q433_12970	COG2211	Major facilitator Superfamily
Q433_12980	COG0346	lactoylglutathione lyase activity
Q433_12985	COG1072	(Pantothenic acid kinase))
Q433_12990	COG3048	D-serine ammonia-lyase activity
Q433_12995	COG0300	oxidoreductase activity
Q433_13000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_13005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_13010	COG4187	Peptidase family M20/M25/M40
Q433_13015	COG1902	pentaerythritol trinitrate reductase activity
Q433_13020	COG0596	Alpha beta hydrolase
Q433_13030	COG1234	tRNA 3'-trailer cleavage
Q433_13035	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Q433_13045	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Q433_13050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Q433_13060	COG0706	membrane insertase activity
Q433_13065	COG3361	conserved protein (COG2071)
Q433_13070	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q433_13075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Q433_13080	COG0346	lactoylglutathione lyase activity
Q433_13090	COG1376	ErfK ybiS ycfS ynhG family protein
Q433_13095	COG4129	membrane
Q433_13100	COG1126	abc transporter atp-binding protein
Q433_13105	COG0765	amino acid transport
Q433_13110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_13125	COG1597	lipid kinase activity
Q433_13130	COG2814	Major facilitator Superfamily
Q433_13135	COG4978	Transcriptional regulator
Q433_13135	COG0789	Transcriptional regulator
Q433_13140	COG0508	dehydrogenase complex catalyzes the overall conversion of
Q433_13145	COG0022	dehydrogenase e1 component
Q433_13150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Q433_13155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Q433_13160	COG3426	butyrate kinase activity
Q433_13165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q433_13170	COG0280	phosphate acetyltransferase
Q433_13175	COG3829	transcription factor binding
Q433_13175	COG3290	protein histidine kinase activity
Q433_13185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Q433_13190	COG2079	MmgE PrpD family protein
Q433_13195	COG0372	Belongs to the citrate synthase family
Q433_13200	COG1960	acyl-CoA dehydrogenase activity
Q433_13205	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q433_13210	COG0183	Belongs to the thiolase family
Q433_13215	COG0584	glycerophosphoryl diester phosphodiesterase
Q433_13220	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_13240	COG1902	pentaerythritol trinitrate reductase activity
Q433_13250	COG0745	RESPONSE REGULATOR receiver
Q433_13260	COG0750	zinc metalloprotease
Q433_13265	COG0497	DNA recombination
Q433_13270	COG1438	arginine binding
Q433_13275	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Q433_13280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Q433_13290	COG0142	geranyltranstransferase activity
Q433_13295	COG1722	exodeoxyribonuclease VII activity
Q433_13300	COG1570	exodeoxyribonuclease VII activity
Q433_13305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Q433_13310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Q433_13320	COG1302	Protein conserved in bacteria
Q433_13325	COG0439	Biotin carboxylase
Q433_13330	COG0511	ligase activity, forming carbon-carbon bonds
Q433_13370	COG3854	ATPases associated with a variety of cellular activities
Q433_13380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Q433_13385	COG0006	proline dipeptidase activity
Q433_13390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Q433_13400	COG3872	metal-dependent enzyme
Q433_13410	COG1752	Esterase of the alpha-beta hydrolase superfamily
Q433_13415	COG1321	iron dependent repressor
Q433_13420	COG0095	Lipoate-protein ligase
Q433_13425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_13430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q433_13435	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Q433_13440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Q433_13445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q433_13460	COG1396	sequence-specific DNA binding
Q433_13470	COG0681	Belongs to the peptidase S26 family
Q433_13495	COG4940	Competence protein ComGF
Q433_13505	COG4970	Tfp pilus assembly protein FimT
Q433_13510	COG4537	Required for transformation and DNA binding
Q433_13515	COG1459	type II secretion system
Q433_13520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Q433_13530	COG0517	IMP dehydrogenase activity
Q433_13535	COG0598	Magnesium transport protein CorA
Q433_13540	COG1253	flavin adenine dinucleotide binding
Q433_13545	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_13555	COG1393	Belongs to the ArsC family
Q433_13580	COG0011	TIGRFAM Protein of
Q433_13590	COG2866	Carboxypeptidase
Q433_13595	COG1368	sulfuric ester hydrolase activity
Q433_13600	COG1940	carbohydrate kinase activity
Q433_13605	COG4483	Protein conserved in bacteria
Q433_13610	COG0705	Rhomboid family
Q433_13610	COG0457	Tetratricopeptide repeat
Q433_13620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Q433_13630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Q433_13635	COG0438	transferase activity, transferring glycosyl groups
Q433_13655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Q433_13660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q433_13665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Q433_13670	COG0581	inorganic phosphate transmembrane transporter activity
Q433_13675	COG0573	inorganic phosphate transmembrane transporter activity
Q433_13680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Q433_13690	COG0477	Major facilitator Superfamily
Q433_13695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Q433_13700	COG2839	Protein conserved in bacteria
Q433_13705	COG5521	maltodextrose utilization protein MalA
Q433_13710	COG1388	LysM domain
Q433_13715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Q433_13720	COG4709	membrane
Q433_13725	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
Q433_13730	COG0735	belongs to the Fur family
Q433_13735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_13745	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Q433_13750	COG0513	Belongs to the DEAD box helicase family
Q433_13760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Q433_13765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Q433_13770	COG2384	SAM-dependent methyltransferase
Q433_13775	COG2010	Cytochrome c
Q433_13785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Q433_13790	COG0358	DNA primase activity
Q433_13795	COG1671	Belongs to the UPF0178 family
Q433_13800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Q433_13805	COG0517	IMP dehydrogenase activity
Q433_13810	COG0751	glycine-tRNA ligase activity
Q433_13815	COG0752	glycyl-tRNA synthetase alpha subunit
Q433_13820	COG1381	Involved in DNA repair and RecF pathway recombination
Q433_13830	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Q433_13835	COG0295	cytidine deaminase activity
Q433_13845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Q433_13850	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Q433_13855	COG1480	7TM receptor with intracellular HD hydrolase
Q433_13865	COG1702	phosphate starvation-inducible protein PhoH
Q433_13870	COG0561	phosphatase activity
Q433_13885	COG4864	UPF0365 protein
Q433_13890	COG1030	water channel activity
Q433_13895	COG1610	YqeY-like protein
Q433_13900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Q433_13905	COG1283	sodium-dependent phosphate transmembrane transporter activity
Q433_13910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Q433_13915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Q433_13920	COG2264	protein methyltransferase activity
Q433_13925	COG0484	heat shock protein binding
Q433_13930	COG0443	Heat shock 70 kDa protein
Q433_13935	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Q433_13940	COG1420	regulation of RNA biosynthetic process
Q433_13945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Q433_13950	COG0481	GTPase activity
Q433_13960	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_13965	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Q433_13970	COG0268	Binds directly to 16S ribosomal RNA
Q433_13975	COG1466	dna polymerase III delta subunit
Q433_13990	COG0658	competence protein
Q433_13990	COG2333	competence protein COMEC
Q433_13995	COG2131	deaminase
Q433_14000	COG1555	photosystem II stabilization
Q433_14000	COG1596	polysaccharide export
Q433_14005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Q433_14010	COG2226	methyltransferase
Q433_14015	COG0799	negative regulation of ribosome biogenesis
Q433_14020	COG1713	HD superfamily hydrolase involved in NAD metabolism
Q433_14025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Q433_14030	COG1534	Rna-binding protein
Q433_14035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Q433_14040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Q433_14045	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Q433_14065	COG2755	lipolytic protein G-D-S-L family
Q433_14075	COG3409	Peptidoglycan-binding domain 1 protein
Q433_14075	COG5632	N-Acetylmuramoyl-L-alanine amidase
Q433_14080	COG0398	Pfam SNARE associated Golgi protein
Q433_14085	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Q433_14095	COG3209	COG3209 Rhs family protein
Q433_14115	COG5002	protein histidine kinase activity
Q433_14115	COG0642	Histidine kinase
Q433_14120	COG0745	RESPONSE REGULATOR receiver
Q433_14125	COG2311	Membrane
Q433_14135	COG0454	-acetyltransferase
Q433_14140	COG2249	NAD(P)H dehydrogenase (quinone) activity
Q433_14155	COG0730	response to heat
Q433_14160	COG0425	Belongs to the sulfur carrier protein TusA family
Q433_14165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_14165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_14175	COG0425	Belongs to the sulfur carrier protein TusA family
Q433_14175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_14185	COG1937	Protein conserved in bacteria
Q433_14195	COG0662	Cupin 2, conserved barrel domain protein
Q433_14210	COG0789	Transcriptional regulator
Q433_14210	COG4978	Transcriptional regulator
Q433_14215	COG2814	Major facilitator Superfamily
Q433_14220	COG0456	acetyltransferase
Q433_14225	COG1253	flavin adenine dinucleotide binding
Q433_14240	COG0697	spore germination
Q433_14245	COG0583	DNA-binding transcription factor activity
Q433_14250	COG2072	flavoprotein involved in K transport
Q433_14255	COG1230	cation diffusion facilitator family transporter
Q433_14260	COG1942	4-Oxalocrotonate Tautomerase
Q433_14265	COG0583	DNA-binding transcription factor activity
Q433_14280	COG1687	branched-chain amino acid
Q433_14285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Q433_14290	COG1522	sequence-specific DNA binding
Q433_14300	COG2124	cytochrome p450
Q433_14315	COG1335	isochorismatase
Q433_14330	COG2318	DinB family
Q433_14340	COG2070	2-Nitropropane dioxygenase
Q433_14350	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Q433_14365	COG2186	Transcriptional regulator
Q433_14380	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_14385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Q433_14390	COG3959	Transketolase, thiamine diphosphate binding domain
Q433_14405	COG4978	Transcriptional regulator
Q433_14405	COG0789	Transcriptional regulator
Q433_14410	COG2315	Protein conserved in bacteria
Q433_14425	COG3443	Belongs to the bacterial solute-binding protein 9 family
Q433_14430	COG1595	DNA-templated transcription, initiation
Q433_14435	COG0667	Aldo Keto reductase
Q433_14440	COG2851	Citrate transporter
Q433_14445	COG0583	DNA-binding transcription factor activity
Q433_14450	COG2828	Protein conserved in bacteria
Q433_14455	COG3409	Peptidoglycan-binding domain 1 protein
Q433_14465	COG5566	PFAM Mor transcription activator
Q433_14470	COG0596	Alpha beta hydrolase
Q433_14475	COG4991	sh3 domain protein
Q433_14480	COG4991	sh3 domain protein
Q433_14490	COG0346	lactoylglutathione lyase activity
Q433_14500	COG5577	PFAM Coat F domain
Q433_14505	COG1063	alcohol dehydrogenase
Q433_14515	COG5577	PFAM Coat F domain
Q433_14520	COG0789	Transcriptional regulator
Q433_14530	COG1064	alcohol dehydrogenase
Q433_14535	COG0693	protein deglycase activity
Q433_14540	COG1621	beta-fructofuranosidase activity
Q433_14545	COG3716	PTS system mannose fructose sorbose family IID component
Q433_14550	COG3715	PTS system
Q433_14555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_14560	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_14565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Q433_14565	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Q433_14575	COG1113	amino acid transport
Q433_14580	COG1280	lysine exporter protein (LysE YggA)
Q433_14585	COG1378	Sugar-specific transcriptional regulator TrmB
Q433_14590	COG1595	DNA-templated transcription, initiation
Q433_14610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q433_14610	COG2124	cytochrome p450
Q433_14615	COG1309	transcriptional regulator
Q433_14620	COG2226	methyltransferase
Q433_14650	COG2116	formate transmembrane transporter activity
Q433_14660	COG5609	conserved protein (DUF2294)
Q433_14665	COG3383	formate dehydrogenase (NAD+) activity
Q433_14670	COG2427	Protein of unknown function (DUF1641)
Q433_14680	COG0626	cystathionine gamma-synthase activity
Q433_14685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q433_14690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Q433_14695	COG2226	methyltransferase
Q433_14710	COG0768	penicillin binding
Q433_14715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Q433_14720	COG0572	uridine kinase
Q433_14740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Q433_14745	COG3906	Belongs to the UPF0473 family
Q433_14750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Q433_14755	COG4472	Bacterial protein of unknown function (DUF965)
Q433_14760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Q433_14765	COG0628	permease
Q433_14770	COG1126	abc transporter atp-binding protein
Q433_14775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_14780	COG0765	amino acid transport
Q433_14785	COG0765	amino acid transport
Q433_14800	COG3881	PFAM PRC-barrel domain
Q433_14805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Q433_14810	COG0457	Tetratricopeptide repeat
Q433_14815	COG0482	sulfurtransferase activity
Q433_14820	COG1104	cysteine desulfurase activity
Q433_14825	COG1959	2 iron, 2 sulfur cluster binding
Q433_14830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Q433_14835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Q433_14845	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Q433_14850	COG0124	histidyl-tRNA synthetase
Q433_14865	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_14865	COG3103	Sh3 type 3 domain protein
Q433_14865	COG4991	sh3 domain protein
Q433_14870	COG1490	D-aminoacyl-tRNA deacylase activity
Q433_14875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Q433_14880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Q433_14885	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Q433_14885	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Q433_14890	COG5416	Lipopolysaccharide assembly protein A domain
Q433_14895	COG0490	domain, Protein
Q433_14905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q433_14905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Q433_14915	COG2244	polysaccharide biosynthetic process
Q433_14920	COG2323	membrane
Q433_14935	COG1862	Preprotein translocase
Q433_14940	COG0343	queuine tRNA-ribosyltransferase activity
Q433_14945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Q433_14955	COG2255	four-way junction helicase activity
Q433_14960	COG0632	four-way junction helicase activity
Q433_14970	COG2814	Major facilitator Superfamily
Q433_14975	COG0673	inositol 2-dehydrogenase activity
Q433_14980	COG2112	serine threonine protein kinase
Q433_15000	COG1115	amino acid carrier protein
Q433_15005	COG0217	transcriptional regulatory protein
Q433_15015	COG1388	LysM domain
Q433_15020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Q433_15025	COG0157	Belongs to the NadC ModD family
Q433_15030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Q433_15035	COG1104	cysteine desulfurase activity
Q433_15040	COG1827	regulation of RNA biosynthetic process
Q433_15045	COG0077	Prephenate dehydratase
Q433_15050	COG4492	Belongs to the UPF0735 family
Q433_15055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Q433_15060	COG3290	protein histidine kinase activity
Q433_15070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Q433_15075	COG2868	ribosomal protein
Q433_15080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Q433_15085	COG1994	Peptidase M50
Q433_15090	COG0739	heme binding
Q433_15100	COG2894	cell division
Q433_15105	COG0850	regulation of cytokinetic process
Q433_15110	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Q433_15115	COG1792	Involved in formation and maintenance of cell shape
Q433_15120	COG1077	Cell shape determining protein MreB Mrl
Q433_15125	COG2003	Belongs to the UPF0758 family
Q433_15130	COG0424	maF-like protein
Q433_15140	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Q433_15150	COG0285	dihydrofolate synthase activity
Q433_15155	COG0525	valine-tRNA ligase activity
Q433_15170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_15175	COG1388	LysM domain
Q433_15180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Q433_15185	COG0113	porphobilinogen synthase activity
Q433_15190	COG1587	Uroporphyrinogen-III synthase
Q433_15195	COG0181	hydroxymethylbilane synthase activity
Q433_15200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Q433_15205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Q433_15215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Q433_15220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Q433_15225	COG1067	ATP-dependent peptidase activity
Q433_15225	COG0470	DNA polymerase III
Q433_15235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Q433_15240	COG0544	peptidyl-prolyl cis-trans isomerase activity
Q433_15245	COG1477	protein flavinylation
Q433_15245	COG0457	Tetratricopeptide repeat
Q433_15255	COG0066	3-isopropylmalate dehydratase activity
Q433_15260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Q433_15265	COG0473	3-isopropylmalate dehydrogenase activity
Q433_15270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Q433_15275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Q433_15280	COG0440	acetolactate synthase activity
Q433_15285	COG0028	Belongs to the TPP enzyme family
Q433_15305	COG0454	-acetyltransferase
Q433_15315	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
Q433_15325	COG0622	Phosphoesterase
Q433_15330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Q433_15335	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Q433_15340	COG5401	PFAM Sporulation and spore germination
Q433_15345	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Q433_15350	COG1846	Transcriptional regulator
Q433_15360	COG2197	response regulator
Q433_15365	COG0824	Thioesterase
Q433_15370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Q433_15375	COG1053	succinate dehydrogenase
Q433_15380	COG2009	succinate dehydrogenase
Q433_15390	COG1719	4-vinyl reductase, 4VR
Q433_15395	COG0527	aspartate kinase activity
Q433_15405	COG0322	excinuclease ABC activity
Q433_15410	COG3118	belongs to the thioredoxin family
Q433_15425	COG3534	alpha-L-arabinofuranosidase
Q433_15430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Q433_15435	COG2086	electron transfer activity
Q433_15440	COG1024	Enoyl-CoA hydratase
Q433_15445	COG1309	transcriptional regulator
Q433_15450	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_15460	COG3766	membrane
Q433_15465	COG1193	negative regulation of DNA recombination
Q433_15470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Q433_15470	COG1796	DNA polymerase
Q433_15475	COG1286	toxin biosynthetic process
Q433_15480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Q433_15485	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Q433_15490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_15490	COG0072	phenylalanine-tRNA ligase activity
Q433_15495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Q433_15505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Q433_15515	COG3835	regulator
Q433_15520	COG0277	FAD linked oxidase domain protein
Q433_15525	COG0247	lactate metabolic process
Q433_15530	COG0346	lactoylglutathione lyase activity
Q433_15535	COG1966	Carbon starvation protein
Q433_15540	COG3534	alpha-L-arabinofuranosidase
Q433_15545	COG0395	ABC-type sugar transport system, permease component
Q433_15550	COG1175	transmembrane transport
Q433_15555	COG1653	transport
Q433_15560	COG0371	Dehydrogenase
Q433_15565	COG0647	UMP catabolic process
Q433_15570	COG0235	Class ii aldolase
Q433_15575	COG1069	ribulokinase activity
Q433_15580	COG2160	L-arabinose isomerase activity
Q433_15590	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_15595	COG1363	Peptidase, m42
Q433_15605	COG3326	Membrane
Q433_15610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Q433_15615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Q433_15620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Q433_15640	COG1346	cytolysis
Q433_15645	COG1380	Effector of murein hydrolase LrgA
Q433_15655	COG3279	Response regulator of the LytR AlgR family
Q433_15660	COG3275	phosphorelay sensor kinase activity
Q433_15670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Q433_15685	COG0398	Pfam SNARE associated Golgi protein
Q433_15690	COG1484	DNA-dependent DNA replication
Q433_15695	COG3611	Membrane attachment protein
Q433_15700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Q433_15710	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Q433_15715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Q433_15720	COG1733	regulation of RNA biosynthetic process
Q433_15725	COG2814	Major facilitator Superfamily
Q433_15730	COG0656	L-ascorbic acid biosynthetic process
Q433_15735	COG0237	dephospho-CoA kinase activity
Q433_15740	COG1971	Probably functions as a manganese efflux pump
Q433_15745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Q433_15750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q433_15750	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Q433_15760	COG5002	protein histidine kinase activity
Q433_15765	COG0745	RESPONSE REGULATOR receiver
Q433_15775	COG0039	L-malate dehydrogenase activity
Q433_15780	COG0538	isocitrate dehydrogenase activity
Q433_15785	COG0372	Belongs to the citrate synthase family
Q433_15795	COG2707	UPF0756 membrane protein
Q433_15800	COG0628	permease
Q433_15805	COG3030	protein affecting phage T7 exclusion by the F plasmid
Q433_15810	COG0469	pyruvate kinase activity
Q433_15815	COG0205	6-phosphofructokinase activity
Q433_15825	COG0825	malonyl-CoA metabolic process
Q433_15830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Q433_15835	COG0281	malic enzyme
Q433_15840	COG0587	DNA-directed DNA polymerase activity
Q433_15860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Q433_15875	COG4109	DRTGG domain
Q433_15885	COG0730	response to heat
Q433_15890	COG1473	amidohydrolase
Q433_15895	COG0196	riboflavin kinase activity
Q433_15900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_15905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Q433_15910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_15915	COG1126	abc transporter atp-binding protein
Q433_15920	COG0765	amino acid transport
Q433_15925	COG0765	amino acid transport
Q433_15930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_15935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_15940	COG0454	-acetyltransferase
Q433_15945	COG0583	DNA-binding transcription factor activity
Q433_15950	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Q433_15955	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_15970	COG0165	Argininosuccinate lyase
Q433_15975	COG0137	argininosuccinate synthase activity
Q433_15985	COG0521	Mo-molybdopterin cofactor biosynthetic process
Q433_15990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Q433_16000	COG0827	DNA restriction-modification system
Q433_16005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Q433_16010	COG3874	Sporulation protein YtfJ
Q433_16020	COG1714	RDD family
Q433_16025	COG0616	signal peptide processing
Q433_16035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Q433_16040	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Q433_16045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q433_16055	COG0301	tRNA thio-modification
Q433_16060	COG1104	cysteine desulfurase activity
Q433_16065	COG1114	Component of the transport system for branched-chain amino acids
Q433_16070	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
Q433_16075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Q433_16080	COG1309	transcriptional regulator
Q433_16085	COG1956	GAF domain-containing protein
Q433_16090	COG2203	Gaf domain
Q433_16090	COG2199	diguanylate cyclase activity
Q433_16100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Q433_16110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Q433_16120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Q433_16125	COG0454	-acetyltransferase
Q433_16130	COG0517	IMP dehydrogenase activity
Q433_16135	COG0123	including yeast histone deacetylase and acetoin utilization protein
Q433_16140	COG1360	Flagellar Motor Protein
Q433_16145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Q433_16150	COG1609	Transcriptional regulator
Q433_16155	COG1605	Chorismate mutase
Q433_16155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Q433_16160	COG3118	belongs to the thioredoxin family
Q433_16165	COG4980	gas vesicle protein
Q433_16170	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
Q433_16175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Q433_16180	COG1674	ftsk spoiiie
Q433_16185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Q433_16190	COG4848	Belongs to the UPF0354 family
Q433_16195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_16210	COG1363	Peptidase, m42
Q433_16215	COG5584	Small secreted protein
Q433_16220	COG0281	malic enzyme
Q433_16225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_16230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Q433_16240	COG0510	thiamine kinase activity
Q433_16245	COG1523	belongs to the glycosyl hydrolase 13 family
Q433_16250	COG1597	lipid kinase activity
Q433_16260	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Q433_16265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Q433_16270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_16275	COG2252	PERMEase
Q433_16280	COG4473	ABC transporter
Q433_16285	COG1131	(ABC) transporter
Q433_16290	COG1349	DNA-binding transcription factor activity
Q433_16295	COG1187	pseudouridine synthase activity
Q433_16305	COG2244	polysaccharide biosynthetic process
Q433_16310	COG2081	HI0933 family
Q433_16320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Q433_16330	COG5578	integral membrane protein
Q433_16335	COG0673	inositol 2-dehydrogenase activity
Q433_16340	COG1653	transport
Q433_16345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Q433_16350	COG4209	transmembrane transport
Q433_16355	COG2207	Transcriptional regulator
Q433_16360	COG1653	transport
Q433_16365	COG0395	ABC-type sugar transport system, permease component
Q433_16370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_16375	COG2124	cytochrome p450
Q433_16380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Q433_16390	COG0156	8-amino-7-oxononanoate synthase activity
Q433_16395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Q433_16405	COG1073	alpha beta
Q433_16430	COG1486	melibiose metabolic process
Q433_16435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Q433_16440	COG0495	leucyl-tRNA aminoacylation
Q433_16455	COG1366	Belongs to the anti-sigma-factor antagonist family
Q433_16455	COG2202	Pas domain
Q433_16460	COG2814	Major facilitator Superfamily
Q433_16470	COG2433	Pfam Transposase IS66
Q433_16475	COG0577	efflux transmembrane transporter activity
Q433_16480	COG1136	(ABC) transporter
Q433_16485	COG2205	protein histidine kinase activity
Q433_16490	COG0745	RESPONSE REGULATOR receiver
Q433_16495	COG0577	efflux transmembrane transporter activity
Q433_16500	COG1136	(ABC) transporter
Q433_16515	COG1131	(ABC) transporter
Q433_16520	COG1725	Transcriptional regulator
Q433_16535	COG1242	4 iron, 4 sulfur cluster binding
Q433_16540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Q433_16550	COG2267	carboxylic ester hydrolase activity
Q433_16555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Q433_16560	COG1113	amino acid transport
Q433_16565	COG0367	asparagine synthase
Q433_16570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Q433_16580	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Q433_16590	COG1506	peptidase
Q433_16595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Q433_16600	COG1116	anion transmembrane transporter activity
Q433_16605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Q433_16610	COG0494	nUDIX hydrolase
Q433_16615	COG4824	toxin secretion phage lysis holin
Q433_16625	COG0783	Belongs to the Dps family
Q433_16640	COG1854	S-ribosylhomocysteine lyase activity
Q433_16645	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Q433_16650	COG0288	reversible hydration of carbon dioxide
Q433_16655	COG0254	rRNA binding
Q433_16660	COG1271	oxidase subunit
Q433_16665	COG1294	oxidase, subunit
Q433_16675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q433_16680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Q433_16680	COG1321	iron dependent repressor
Q433_16685	COG1121	(ABC) transporter
Q433_16690	COG0803	Belongs to the bacterial solute-binding protein 9 family
Q433_16700	COG4948	Mandelate Racemase Muconate Lactonizing
Q433_16705	COG0318	PFAM AMP-dependent synthetase and ligase
Q433_16710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Q433_16715	COG0596	Alpha beta hydrolase
Q433_16720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Q433_16725	COG1169	isochorismate synthase
Q433_16735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Q433_16740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Q433_16750	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q433_16755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Q433_16760	COG0438	transferase activity, transferring glycosyl groups
Q433_16770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_16775	COG0438	transferase activity, transferring glycosyl groups
Q433_16780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_16785	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Q433_16790	COG0058	SHG alpha-glucan phosphorylase activity
Q433_16795	COG0297	glycogen (starch) synthase activity
Q433_16800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q433_16805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Q433_16940	COG3859	Proton-coupled thiamine transporter YuaJ
Q433_16945	COG1247	-acetyltransferase
Q433_16950	COG2268	Band 7 protein
Q433_16955	COG1585	Membrane protein implicated in regulation of membrane protease activity
Q433_16960	COG2318	DinB family
Q433_16970	COG1454	alcohol dehydrogenase
Q433_16980	COG1510	regulation of RNA biosynthetic process
Q433_16990	COG0569	domain protein
Q433_16995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Q433_17000	COG4682	membrane
Q433_17005	COG1705	Flagellar rod assembly protein muramidase FlgJ
Q433_17010	COG0477	Major facilitator Superfamily
Q433_17015	COG5553	Cysteine dioxygenase type I
Q433_17030	COG1968	undecaprenyl-diphosphatase activity
Q433_17035	COG0628	permease
Q433_17040	COG0673	inositol 2-dehydrogenase activity
Q433_17045	COG4806	L-rhamnose isomerase
Q433_17050	COG3254	rhamnose metabolic process
Q433_17055	COG1070	Carbohydrate kinase
Q433_17060	COG1349	DNA-binding transcription factor activity
Q433_17065	COG3347	Dehydrogenase
Q433_17065	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_17070	COG0840	transmembrane signaling receptor activity
Q433_17075	COG0840	transmembrane signaling receptor activity
Q433_17080	COG0840	transmembrane signaling receptor activity
Q433_17085	COG0840	transmembrane signaling receptor activity
Q433_17105	COG0432	Pfam Uncharacterised protein family UPF0047
Q433_17115	COG0366	Alpha amylase catalytic
Q433_17120	COG1253	flavin adenine dinucleotide binding
Q433_17125	COG2738	Putative neutral zinc metallopeptidase
Q433_17140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Q433_17155	COG0166	Belongs to the GPI family
Q433_17160	COG1979	alcohol dehydrogenase
Q433_17165	COG1979	alcohol dehydrogenase
Q433_17175	COG2155	Conserved Protein
Q433_17180	COG1098	S1 RNA binding domain
Q433_17185	COG0436	Aminotransferase
Q433_17190	COG1522	sequence-specific DNA binding
Q433_17195	COG2267	carboxylic ester hydrolase activity
Q433_17205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Q433_17210	COG2205	protein histidine kinase activity
Q433_17220	COG5018	Exonuclease
Q433_17230	COG2814	Major facilitator Superfamily
Q433_17235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_17240	COG3011	Protein conserved in bacteria
Q433_17255	COG4565	transcriptional regulatory protein
Q433_17280	COG3493	citrate carrier protein
Q433_17290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Q433_17290	COG2111	Na H antiporter
Q433_17295	COG2111	Na H antiporter
Q433_17300	COG1006	Multisubunit Na H antiporter MnhC subunit
Q433_17305	COG0651	ATP synthesis coupled electron transport
Q433_17310	COG1863	multisubunit Na H antiporter MnhE subunit
Q433_17315	COG2212	antiporter activity
Q433_17320	COG1320	monovalent cation:proton antiporter activity
Q433_17325	COG2050	protein possibly involved in aromatic compounds catabolism
Q433_17330	COG2197	response regulator
Q433_17335	COG4585	Histidine kinase
Q433_17345	COG0142	geranyltranstransferase activity
Q433_17365	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Q433_17370	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Q433_17375	COG1335	isochorismatase
Q433_17380	COG5506	Protein of unknown function (DUF1694)
Q433_17395	COG0628	permease
Q433_17410	COG1418	mRNA catabolic process
Q433_17415	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_17425	COG1511	domain protein
Q433_17430	COG1674	ftsk spoiiie
Q433_17430	COG0433	COG0433 Predicted ATPase
Q433_17435	COG4499	WXG100 protein secretion system (Wss), protein YukC
Q433_17440	COG5417	Belongs to the EsaB family
Q433_17445	COG4842	Belongs to the WXG100 family
Q433_17460	COG2508	Transcriptional regulator
Q433_17460	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Q433_17465	COG0686	Belongs to the AlaDH PNT family
Q433_17470	COG5634	Uncharacterized conserved protein (DUF2278)
Q433_17475	COG3251	PFAM MbtH domain protein
Q433_17480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_17485	COG3433	isochorismatase activity
Q433_17485	COG1535	isochorismatase
Q433_17490	COG1021	2,3-dihydroxybenzoate-AMP ligase
Q433_17495	COG1169	isochorismate synthase
Q433_17500	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_17505	COG2819	hydrolase of the alpha beta superfamily
Q433_17520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Q433_17525	COG1268	BioY protein
Q433_17530	COG2056	Na+-H+ antiporter family
Q433_17535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Q433_17540	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Q433_17545	COG3584	3D domain protein
Q433_17560	COG1252	NADH dehydrogenase
Q433_17570	COG0492	ferredoxin-NADP+ reductase activity
Q433_17580	COG0516	GMP reductase activity
Q433_17585	COG2808	Putative FMN-binding domain
Q433_17590	COG0456	acetyltransferase
Q433_17595	COG0316	Belongs to the HesB IscA family
Q433_17600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Q433_17610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Q433_17615	COG4844	belongs to the
Q433_17620	COG1252	NADH dehydrogenase
Q433_17625	COG4837	Protein of unknown function (DUF1462)
Q433_17630	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Q433_17635	COG1506	peptidase
Q433_17635	COG0823	Involved in the tonB-independent uptake of proteins
Q433_17635	COG4946	Tricorn protease homolog
Q433_17640	COG0083	homoserine kinase activity
Q433_17645	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Q433_17650	COG0460	homoserine dehydrogenase
Q433_17655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Q433_17665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Q433_17670	COG0647	UMP catabolic process
Q433_17675	COG2445	Protein of unknown function DUF86
Q433_17680	COG4470	Protein conserved in bacteria
Q433_17690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Q433_17695	COG0739	heme binding
Q433_17705	COG3377	Domain of unknown function (DUF1805)
Q433_17710	COG0737	Belongs to the 5'-nucleotidase family
Q433_17715	COG0730	response to heat
Q433_17720	COG1801	Protein of unknown function DUF72
Q433_17730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Q433_17735	COG2508	Transcriptional regulator
Q433_17740	COG2233	PERMEase
Q433_17745	COG2233	PERMEase
Q433_17750	COG3195	allantoin biosynthetic process
Q433_17750	COG3648	Uricase
Q433_17755	COG2351	hydroxyisourate hydrolase activity
Q433_17770	COG2080	2 iron, 2 sulfur cluster binding
Q433_17775	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Q433_17780	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Q433_17785	COG2068	MobA-Related Protein
Q433_17790	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Q433_17795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Q433_17800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Q433_17810	COG2356	endonuclease I
Q433_17815	COG3842	ATPase activity
Q433_17820	COG2188	Transcriptional regulator
Q433_17825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_17830	COG0395	ABC-type sugar transport system, permease component
Q433_17835	COG1175	transmembrane transport
Q433_17840	COG1653	transport
Q433_17845	COG2222	sugar isomerase
Q433_17850	COG0322	excinuclease ABC activity
Q433_17855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Q433_17870	COG0346	lactoylglutathione lyase activity
Q433_17875	COG0640	Transcriptional regulator
Q433_17880	COG0719	Fe-S assembly protein
Q433_17885	COG0822	iron-sulfur transferase activity
Q433_17890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Q433_17895	COG0719	Fe-S assembly protein
Q433_17900	COG0396	ATPase activity
Q433_17920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Q433_17925	COG1464	Belongs to the NlpA lipoprotein family
Q433_17930	COG2011	ABC-type metal ion transport system permease component
Q433_17935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Q433_17950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Q433_17955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Q433_17965	COG0509	glycine decarboxylation via glycine cleavage system
Q433_17970	COG1393	Belongs to the ArsC family
Q433_17975	COG1960	acyl-CoA dehydrogenase activity
Q433_17980	COG0183	Belongs to the thiolase family
Q433_17985	COG1024	Enoyl-CoA hydratase
Q433_17985	COG1250	3-hydroxyacyl-CoA dehydrogenase
Q433_17995	COG0506	proline dehydrogenase activity
Q433_18005	COG5577	PFAM Coat F domain
Q433_18010	COG1846	Transcriptional regulator
Q433_18015	COG0477	Major facilitator Superfamily
Q433_18020	COG1942	4-Oxalocrotonate Tautomerase
Q433_18025	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_18030	COG0583	DNA-binding transcription factor activity
Q433_18040	COG1120	ATPase activity
Q433_18055	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_18060	COG0783	Belongs to the Dps family
Q433_18065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q433_18080	COG2770	Histidine kinase
Q433_18080	COG2205	protein histidine kinase activity
Q433_18090	COG1309	transcriptional regulator
Q433_18095	COG0114	fumarate hydratase activity
Q433_18105	COG0697	spore germination
Q433_18110	COG0814	amino acid
Q433_18120	COG2197	response regulator
Q433_18125	COG4585	Histidine kinase
Q433_18130	COG4758	membrane
Q433_18135	COG3595	metallopeptidase activity
Q433_18140	COG1842	Phage shock protein A
Q433_18145	COG4758	membrane
Q433_18150	COG2814	Major facilitator Superfamily
Q433_18160	COG2096	Adenosyltransferase
Q433_18165	COG1120	ATPase activity
Q433_18170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_18175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_18185	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_18190	COG3386	PFAM SMP-30 Gluconolaconase
Q433_18195	COG2205	protein histidine kinase activity
Q433_18200	COG0745	RESPONSE REGULATOR receiver
Q433_18215	COG1191	sigma factor activity
Q433_18230	COG2140	Oxalate decarboxylase
Q433_18240	COG0577	efflux transmembrane transporter activity
Q433_18245	COG1136	(ABC) transporter
Q433_18250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Q433_18260	COG1120	ATPase activity
Q433_18265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_18270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Q433_18275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_18285	COG0531	amino acid
Q433_18300	COG1988	membrane-bound metal-dependent
Q433_18305	COG1368	sulfuric ester hydrolase activity
Q433_18310	COG1910	domain protein
Q433_18315	COG0725	ABC transporter, periplasmic molybdate-binding protein
Q433_18320	COG4149	molybdate abc transporter
Q433_18325	COG0656	L-ascorbic acid biosynthetic process
Q433_18335	COG0025	NhaP-type Na H and K H
Q433_18340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Q433_18345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Q433_18350	COG3973	AAA domain
Q433_18360	COG2860	membrane
Q433_18370	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Q433_18375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Q433_18380	COG2217	Heavy metal translocating P-type atpase
Q433_18385	COG2217	Heavy metal translocating P-type atpase
Q433_18390	COG2608	mercury ion transmembrane transporter activity
Q433_18395	COG1937	Protein conserved in bacteria
Q433_18400	COG0673	inositol 2-dehydrogenase activity
Q433_18405	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Q433_18410	COG1289	transmembrane transporter activity
Q433_18420	COG2076	Multidrug Resistance protein
Q433_18425	COG1309	transcriptional regulator
Q433_18430	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_18435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Q433_18440	COG0557	exoribonuclease II activity
Q433_18445	COG1647	Serine aminopeptidase, S33
Q433_18450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Q433_18455	COG0596	Alpha beta hydrolase
Q433_18460	COG1476	TRANSCRIPTIONal
Q433_18465	COG1396	sequence-specific DNA binding
Q433_18470	COG1396	sequence-specific DNA binding
Q433_18475	COG1733	regulation of RNA biosynthetic process
Q433_18480	COG0840	transmembrane signaling receptor activity
Q433_18485	COG1174	glycine betaine transport
Q433_18490	COG1732	Glycine betaine
Q433_18495	COG1174	glycine betaine transport
Q433_18500	COG1125	glycine betaine transport
Q433_18500	COG0517	IMP dehydrogenase activity
Q433_18510	COG1510	regulation of RNA biosynthetic process
Q433_18515	COG1174	glycine betaine transport
Q433_18520	COG1732	Glycine betaine
Q433_18525	COG1174	glycine betaine transport
Q433_18530	COG0517	IMP dehydrogenase activity
Q433_18530	COG1125	glycine betaine transport
Q433_18535	COG1510	regulation of RNA biosynthetic process
Q433_18540	COG2095	MarC family integral membrane protein
Q433_18550	COG3064	Membrane
Q433_18555	COG4640	response to antibiotic
Q433_18560	COG0456	acetyltransferase
Q433_18565	COG0148	phosphopyruvate hydratase activity
Q433_18570	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Q433_18575	COG0149	triose-phosphate isomerase activity
Q433_18580	COG0126	phosphoglycerate kinase activity
Q433_18595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Q433_18600	COG2390	Transcriptional regulator
Q433_18605	COG2814	Major facilitator Superfamily
Q433_18610	COG1609	Transcriptional regulator
Q433_18615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_18630	COG0583	DNA-binding transcription factor activity
Q433_18635	COG0697	spore germination
Q433_18640	COG1113	amino acid transport
Q433_18645	COG3858	chitin binding
Q433_18650	COG1556	Lactate utilization protein
Q433_18655	COG1139	Iron-sulfur cluster binding protein
Q433_18660	COG0247	lactate metabolic process
Q433_18665	COG2197	response regulator
Q433_18670	COG4585	Histidine kinase
Q433_18675	COG0842	Transport permease protein
Q433_18680	COG1131	(ABC) transporter
Q433_18690	COG0596	Alpha beta hydrolase
Q433_18695	COG2208	phosphoserine phosphatase activity
Q433_18700	COG3867	Arabinogalactan endo-beta-1,4-galactanase
Q433_18705	COG1874	Beta-galactosidase
Q433_18710	COG3833	ABC-type maltose transport systems, permease component
Q433_18715	COG1175	transmembrane transport
Q433_18720	COG2182	Extracellular solute-binding protein
Q433_18725	COG1609	Transcriptional regulator
Q433_18730	COG2186	Transcriptional regulator
Q433_18735	COG1620	l-lactate permease
Q433_18740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Q433_18755	COG5039	Polysaccharide pyruvyl transferase
Q433_18760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q433_18765	COG0110	maltose O-acetyltransferase activity
Q433_18770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Q433_18775	COG2244	polysaccharide biosynthetic process
Q433_18780	COG1216	Glycosyl transferase, family 2
Q433_18785	COG5039	Polysaccharide pyruvyl transferase
Q433_18790	COG1216	Glycosyl transferase, family 2
Q433_18800	COG0438	transferase activity, transferring glycosyl groups
Q433_18805	COG1215	transferase activity, transferring glycosyl groups
Q433_18810	COG0438	transferase activity, transferring glycosyl groups
Q433_18815	COG1086	Polysaccharide biosynthesis protein
Q433_18820	COG0489	protein tyrosine kinase activity
Q433_18825	COG3944	biosynthesis protein
Q433_18830	COG1396	sequence-specific DNA binding
Q433_18835	COG2272	Belongs to the type-B carboxylesterase lipase family
Q433_18845	COG3479	Phenolic acid decarboxylase
Q433_18855	COG1794	racemase activity, acting on amino acids and derivatives
Q433_18860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Q433_18865	COG1621	beta-fructofuranosidase activity
Q433_18870	COG1621	beta-fructofuranosidase activity
Q433_18875	COG0531	amino acid
Q433_18880	COG1309	transcriptional regulator
Q433_18885	COG2076	Multidrug Resistance protein
Q433_18890	COG2076	Multidrug Resistance protein
Q433_18900	COG0277	FAD linked oxidase domain protein
Q433_18905	COG3621	Patatin-like phospholipase
Q433_18915	COG0740	serine-type endopeptidase activity
Q433_18920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Q433_18925	COG0366	Alpha amylase catalytic
Q433_18930	COG1554	hydrolase, family 65, central catalytic
Q433_18935	COG5521	maltodextrose utilization protein MalA
Q433_18940	COG3833	ABC-type maltose transport systems, permease component
Q433_18945	COG1175	transmembrane transport
Q433_18950	COG2182	Extracellular solute-binding protein
Q433_18955	COG0366	Alpha amylase catalytic
Q433_18960	COG1609	Transcriptional regulator
Q433_18965	COG1611	Belongs to the LOG family
Q433_18970	COG1694	Mazg nucleotide pyrophosphohydrolase
Q433_18975	COG0659	secondary active sulfate transmembrane transporter activity
Q433_18980	COG0288	reversible hydration of carbon dioxide
Q433_18985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Q433_18990	COG0577	efflux transmembrane transporter activity
Q433_18995	COG1136	(ABC) transporter
Q433_19000	COG5002	protein histidine kinase activity
Q433_19005	COG0745	RESPONSE REGULATOR receiver
Q433_19015	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Q433_19020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_19025	COG1481	regulation of sporulation
Q433_19030	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Q433_19035	COG1660	Displays ATPase and GTPase activities
Q433_19040	COG1051	belongs to the nudix hydrolase family
Q433_19050	COG0492	ferredoxin-NADP+ reductase activity
Q433_19055	COG3883	PFAM NLP P60 protein
Q433_19055	COG0791	NLP P60 protein
Q433_19060	COG0457	Tetratricopeptide repeat
Q433_19065	COG1132	(ABC) transporter
Q433_19095	COG0107	imidazoleglycerol-phosphate synthase activity
Q433_19100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Q433_19105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Q433_19110	COG0131	Imidazoleglycerol-phosphate dehydratase
Q433_19115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Q433_19120	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Q433_19125	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Q433_19130	COG4990	cell redox homeostasis
Q433_19135	COG5297	Belongs to the glycosyl hydrolase family 6
Q433_19140	COG0110	maltose O-acetyltransferase activity
Q433_19145	COG0546	phosphoglycolate phosphatase activity
Q433_19150	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Q433_19155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Q433_19160	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Q433_19165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Q433_19170	COG0363	glucosamine-6-phosphate deaminase activity
Q433_19180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Q433_19185	COG1846	Transcriptional regulator
Q433_19190	COG2124	cytochrome p450
Q433_19205	COG1846	Transcriptional regulator
Q433_19210	COG2814	Major facilitator Superfamily
Q433_19215	COG1950	PFAM Membrane protein of
Q433_19220	COG1983	PspC domain protein
Q433_19225	COG3595	metallopeptidase activity
Q433_19240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q433_19250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Q433_19255	COG0556	nucleotide-excision repair
Q433_19260	COG4897	Protein conserved in bacteria
Q433_19270	COG3848	Pyruvate phosphate dikinase
Q433_19270	COG0574	Belongs to the PEP-utilizing enzyme family
Q433_19275	COG1309	transcriptional regulator
Q433_19280	COG2814	Major facilitator Superfamily
Q433_19285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q433_19295	COG3409	Peptidoglycan-binding domain 1 protein
Q433_19295	COG0793	Belongs to the peptidase S41A family
Q433_19300	COG2177	Part of the ABC transporter FtsEX involved in
Q433_19305	COG2884	Cell division ATP-binding protein ftsE
Q433_19310	COG2010	Cytochrome c
Q433_19315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_19320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Q433_19330	COG0653	protein targeting
Q433_19335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Q433_19350	COG1516	flagellar protein fliS
Q433_19355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Q433_19360	COG1334	flagellar protein FlaG
Q433_19365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q433_19370	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Q433_19375	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Q433_19385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Q433_19390	COG4786	Flagellar basal body rod
Q433_19390	COG1256	bacterial-type flagellum assembly
Q433_19395	COG3418	PFAM FlgN family protein
Q433_19400	COG2747	anti-sigma28 factor FlgM
Q433_19410	COG1040	competence protein
Q433_19420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Q433_19425	COG1307	EDD domain protein, DegV family
Q433_19430	COG2197	response regulator
Q433_19435	COG4585	Histidine kinase
Q433_19440	COG1739	Uncharacterized protein family UPF0029
Q433_19445	COG1316	TRANSCRIPTIONal
Q433_19450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Q433_19455	COG0438	transferase activity, transferring glycosyl groups
Q433_19460	COG1215	transferase activity, transferring glycosyl groups
Q433_19465	COG3206	protein involved in exopolysaccharide biosynthesis
Q433_19470	COG3307	-O-antigen
Q433_19475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q433_19480	COG0438	transferase activity, transferring glycosyl groups
Q433_19480	COG0297	glycogen (starch) synthase activity
Q433_19485	COG2244	polysaccharide biosynthetic process
Q433_19500	COG2247	cell wall binding repeat
Q433_19500	COG0860	N-Acetylmuramoyl-L-alanine amidase
Q433_19505	COG2247	cell wall binding repeat
Q433_19505	COG2385	sporulation resulting in formation of a cellular spore
Q433_19515	COG1316	TRANSCRIPTIONal
Q433_19520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Q433_19540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Q433_19545	COG1134	teichoic acid transport
Q433_19550	COG1682	transport, permease protein
Q433_19565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Q433_19565	COG1215	transferase activity, transferring glycosyl groups
Q433_19570	COG0463	Glycosyl transferase, family 2
Q433_19615	COG4193	domain, Protein
Q433_19620	COG1482	cell wall glycoprotein biosynthetic process
Q433_19630	COG0697	spore germination
Q433_19635	COG0814	amino acid
Q433_19645	COG2814	Major facilitator Superfamily
Q433_19650	COG1316	TRANSCRIPTIONal
Q433_19655	COG0561	phosphatase activity
Q433_19660	COG0791	NLP P60 protein
Q433_19670	COG2843	Capsule synthesis protein
Q433_19680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Q433_19695	COG1609	Transcriptional regulator
Q433_19700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_19705	COG1869	D-ribose catabolic process
Q433_19710	COG1129	ABC transporter
Q433_19715	COG1172	Belongs to the binding-protein-dependent transport system permease family
Q433_19720	COG1879	ABC-type sugar transport system periplasmic component
Q433_19725	COG3103	Sh3 type 3 domain protein
Q433_19735	COG2249	NAD(P)H dehydrogenase (quinone) activity
Q433_19740	COG3527	Alpha-acetolactate decarboxylase
Q433_19745	COG0028	Belongs to the TPP enzyme family
Q433_19750	COG0583	DNA-binding transcription factor activity
Q433_19755	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Q433_19770	COG5337	Spore coat protein CotH
Q433_19780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Q433_19790	COG0405	Gamma-glutamyltransferase
Q433_19795	COG1522	sequence-specific DNA binding
Q433_19800	COG2059	Chromate
Q433_19805	COG2059	Chromate
Q433_19815	COG0655	NAD(P)H dehydrogenase (quinone) activity
Q433_19820	COG0583	DNA-binding transcription factor activity
Q433_19850	COG5444	nuclease activity
Q433_19870	COG3878	Protein conserved in bacteria
Q433_19875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Q433_19880	COG4464	protein tyrosine phosphatase activity
Q433_19885	COG0489	protein tyrosine kinase activity
Q433_19890	COG3944	biosynthesis protein
Q433_19900	COG4715	Zinc finger, swim domain protein
Q433_19905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Q433_19915	COG0561	phosphatase activity
Q433_19920	COG1349	DNA-binding transcription factor activity
Q433_19925	COG0629	single-stranded DNA binding
Q433_19940	COG3764	Sortase (surface protein transpeptidase)
Q433_19950	COG2972	Histidine kinase
Q433_19950	COG0745	RESPONSE REGULATOR receiver
Q433_19955	COG1970	mechanosensitive ion channel activity
Q433_19960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Q433_19965	COG0457	Tetratricopeptide repeat
Q433_19970	COG4786	Flagellar basal body rod
Q433_19975	COG4786	Flagellar basal body rod
Q433_19985	COG1077	Cell shape determining protein MreB Mrl
Q433_19990	COG1609	Transcriptional regulator
Q433_20000	COG1846	Transcriptional regulator
Q433_20005	COG2814	Major facilitator Superfamily
Q433_20010	COG3420	alginic acid biosynthetic process
Q433_20015	COG1953	Uracil, thiamine, allantoin
Q433_20020	COG0477	Major facilitator Superfamily
Q433_20025	COG1335	isochorismatase
Q433_20035	COG0004	ammonium transporteR
Q433_20040	COG0347	Belongs to the P(II) protein family
Q433_20045	COG0671	phosphoesterase, PA-phosphatase related
Q433_20055	COG0739	heme binding
Q433_20060	COG1247	-acetyltransferase
Q433_20085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q433_20090	COG0789	Transcriptional regulator
Q433_20100	COG2910	NAD(P)H-binding
Q433_20105	COG1959	2 iron, 2 sulfur cluster binding
Q433_20110	COG0804	urea catabolic process
Q433_20115	COG0832	Belongs to the urease beta subunit family
Q433_20120	COG0831	urea catabolic process
Q433_20135	COG3237	CsbD-like
Q433_20140	COG1994	Peptidase M50
Q433_20145	COG0457	Tetratricopeptide repeat
Q433_20155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Q433_20160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Q433_20170	COG2304	oxidoreductase activity
Q433_20180	COG2304	oxidoreductase activity
Q433_20190	COG2385	sporulation resulting in formation of a cellular spore
Q433_20200	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Q433_20210	COG4836	Membrane
Q433_20225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Q433_20230	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Q433_20235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Q433_20240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Q433_20245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q433_20250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Q433_20260	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Q433_20265	COG0356	it plays a direct role in the translocation of protons across the membrane
Q433_20280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Q433_20285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Q433_20290	COG4475	Protein of unknown function (DUF436)
Q433_20295	COG0698	ribose 5-phosphate isomerase
Q433_20305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Q433_20310	COG1971	Probably functions as a manganese efflux pump
Q433_20315	COG0009	L-threonylcarbamoyladenylate synthase
Q433_20320	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Q433_20340	COG2890	protein-(glutamine-N5) methyltransferase activity
Q433_20345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Q433_20350	COG0346	lactoylglutathione lyase activity
Q433_20355	COG0789	Transcriptional regulator
Q433_20360	COG0679	Auxin Efflux Carrier
Q433_20365	COG0281	malic enzyme
Q433_20370	COG1435	thymidine kinase activity
Q433_20375	COG0254	rRNA binding
Q433_20380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Q433_20390	COG1494	fructose-1,6-bisphosphatase
Q433_20395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Q433_20405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Q433_20410	COG0191	fructose-bisphosphate aldolase activity
Q433_20415	COG2204	response regulator
Q433_20420	COG4821	SIS domain
Q433_20425	COG0504	CTP synthase activity
Q433_20430	COG3343	RNA polymerase activity
Q433_20440	COG1960	acyl-CoA dehydrogenase activity
Q433_20445	COG2181	nitrate reductase activity
Q433_20445	COG0247	lactate metabolic process
Q433_20450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q433_20455	COG4294	response to UV
Q433_20465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q433_20470	COG1132	(ABC) transporter
Q433_20475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Q433_20485	COG2181	nitrate reductase activity
Q433_20490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Q433_20495	COG1140	nitrate reductase beta subunit
Q433_20500	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Q433_20510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q433_20520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Q433_20525	COG2223	nitrite transmembrane transporter activity
Q433_20530	COG0018	arginyl-trna synthetase
Q433_20535	COG4506	Protein conserved in bacteria
Q433_20545	COG0535	radical SAM domain protein
Q433_20555	COG1131	(ABC) transporter
Q433_20560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Q433_20565	COG0612	Peptidase, M16
Q433_20570	COG0612	Peptidase, M16
Q433_20580	COG3391	amine dehydrogenase activity
Q433_20585	COG3391	amine dehydrogenase activity
Q433_20595	COG0457	Tetratricopeptide repeat
Q433_20625	COG1131	(ABC) transporter
Q433_20635	COG0010	Belongs to the arginase family
Q433_20640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Q433_20645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Q433_20655	COG1994	Peptidase M50
Q433_20660	COG1942	4-Oxalocrotonate Tautomerase
Q433_20665	COG1846	Transcriptional regulator
Q433_20670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Q433_20690	COG0477	Major facilitator Superfamily
Q433_20695	COG1959	2 iron, 2 sulfur cluster binding
Q433_20700	COG3465	dGTPase activity
Q433_20705	COG1078	dGTPase activity
Q433_20715	COG4844	belongs to the
Q433_20725	COG0697	spore germination
Q433_20735	COG0095	Lipoate-protein ligase
Q433_20740	COG0583	DNA-binding transcription factor activity
Q433_20745	COG0280	phosphate acetyltransferase
Q433_20755	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_20760	COG0436	Aminotransferase
Q433_20765	COG2814	Major facilitator Superfamily
Q433_20770	COG0151	Belongs to the GarS family
Q433_20775	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_20780	COG1917	Cupin 2, conserved barrel domain protein
Q433_20785	COG0077	Prephenate dehydratase
Q433_20795	COG2814	Major facilitator Superfamily
Q433_20800	COG0833	amino acid
Q433_20805	COG4187	Peptidase family M20/M25/M40
Q433_20810	COG1012	belongs to the aldehyde dehydrogenase family
Q433_20815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Q433_20830	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Q433_20835	COG1091	dTDP-4-dehydrorhamnose reductase activity
Q433_20840	COG1088	dTDP-glucose 4,6-dehydratase activity
Q433_20845	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Q433_20850	COG3980	spore coat polysaccharide biosynthesis protein
Q433_20855	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Q433_20860	COG2089	acid synthase
Q433_20865	COG0456	acetyltransferase
Q433_20870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Q433_20875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Q433_20880	COG0463	Glycosyl transferase, family 2
Q433_20895	COG2363	Small membrane protein
Q433_20900	COG2233	PERMEase
Q433_20915	COG1012	belongs to the aldehyde dehydrogenase family
Q433_20920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Q433_20925	COG1216	Glycosyl transferase, family 2
Q433_20930	COG0351	phosphomethylpyrimidine kinase
Q433_20940	COG1621	beta-fructofuranosidase activity
Q433_20945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_20945	COG1263	PTS System
Q433_20950	COG2116	formate transmembrane transporter activity
Q433_20955	COG3711	transcriptional antiterminator
Q433_20965	COG1404	Belongs to the peptidase S8 family
Q433_20970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Q433_20975	COG0778	Nitroreductase
Q433_20980	COG0772	Belongs to the SEDS family
Q433_20990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Q433_20995	COG1845	cytochrome c oxidase, subunit III
Q433_21000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Q433_21005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Q433_21015	COG2261	transglycosylase associated protein
Q433_21020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Q433_21025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Q433_21030	COG2246	polysaccharide biosynthetic process
Q433_21035	COG1309	transcriptional regulator
Q433_21045	COG3162	membrane
Q433_21050	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Q433_21055	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Q433_21060	COG2837	iron assimilation
Q433_21065	COG2822	iron ion transport
Q433_21070	COG0672	)-iron permease
Q433_21075	COG0352	thiamine-phosphate diphosphorylase activity
Q433_21080	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Q433_21085	COG0583	DNA-binding transcription factor activity
Q433_21090	COG1380	Effector of murein hydrolase LrgA
Q433_21095	COG1346	cytolysis
Q433_21100	COG2814	Major facilitator Superfamily
Q433_21105	COG4895	conserved protein (DUF2196)
Q433_21110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Q433_21120	COG0346	lactoylglutathione lyase activity
Q433_21125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_21135	COG1404	Belongs to the peptidase S8 family
Q433_21150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_21150	COG1263	PTS System
Q433_21155	COG3711	transcriptional antiterminator
Q433_21160	COG1442	glycosyl transferase family 8
Q433_21165	COG5522	Integral membrane protein (intg_mem_TP0381)
Q433_21170	COG1846	Transcriptional regulator
Q433_21175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Q433_21180	COG2234	aminopeptidase activity
Q433_21195	COG2814	Major facilitator Superfamily
Q433_21200	COG2357	RelA SpoT domain protein
Q433_21205	COG1575	Belongs to the MenA family. Type 1 subfamily
Q433_21230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Q433_21235	COG1696	Membrane protein involved in D-alanine export
Q433_21240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Q433_21245	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Q433_21250	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
Q433_21255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Q433_21260	COG1486	melibiose metabolic process
Q433_21265	COG1447	Phosphotransferase system cellobiose-specific component IIA
Q433_21270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_21275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Q433_21280	COG3711	transcriptional antiterminator
Q433_21280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Q433_21290	COG2094	Belongs to the DNA glycosylase MPG family
Q433_21295	COG0753	catalase activity
Q433_21305	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Q433_21310	COG1131	(ABC) transporter
Q433_21330	COG1595	DNA-templated transcription, initiation
Q433_21335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Q433_21340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Q433_21345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Q433_21350	COG4988	ABC transporter
Q433_21355	COG1294	oxidase, subunit
Q433_21360	COG1271	oxidase subunit
Q433_21365	COG3493	citrate carrier protein
Q433_21370	COG0501	Belongs to the peptidase M48B family
Q433_21380	COG0726	polysaccharide deacetylase
Q433_21385	COG3842	ATPase activity
Q433_21390	COG2508	Transcriptional regulator
Q433_21395	COG1012	belongs to the aldehyde dehydrogenase family
Q433_21400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Q433_21415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Q433_21420	COG1881	PFAM PEBP family protein
Q433_21425	COG0583	DNA-binding transcription factor activity
Q433_21440	COG4585	Histidine kinase
Q433_21445	COG2197	response regulator
Q433_21450	COG2195	Cleaves the N-terminal amino acid of tripeptides
Q433_21465	COG4894	glucomannan catabolic process
Q433_21470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Q433_21480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Q433_21485	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_21490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Q433_21495	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Q433_21500	COG2610	gluconate transmembrane transporter activity
Q433_21510	COG0500	methyltransferase
Q433_21520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Q433_21535	COG0693	protein deglycase activity
Q433_21535	COG0753	catalase activity
Q433_21540	COG2851	Citrate transporter
Q433_21545	COG2273	Hydrolase Family 16
Q433_21555	COG3711	transcriptional antiterminator
Q433_21570	COG2270	Major facilitator Superfamily
Q433_21575	COG0513	Belongs to the DEAD box helicase family
Q433_21580	COG3401	FG-GAP repeat protein
Q433_21580	COG2755	lipolytic protein G-D-S-L family
Q433_21635	COG3209	COG3209 Rhs family protein
Q433_21640	COG0697	spore germination
Q433_21650	COG0789	Transcriptional regulator
Q433_21670	COG0589	response to stress
Q433_21675	COG2723	6-phospho-beta-galactosidase activity
Q433_21680	COG1263	PTS System
Q433_21680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Q433_21680	COG2190	(PTS) system
Q433_21695	COG5444	nuclease activity
Q433_21715	COG3507	Belongs to the glycosyl hydrolase 43 family
Q433_21730	COG2986	histidine ammonia-lyase
Q433_21735	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Q433_21740	COG1228	amidohydrolase
Q433_21745	COG0010	Belongs to the arginase family
Q433_21750	COG0833	amino acid
Q433_21755	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Q433_21760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Q433_21765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Q433_21775	COG2390	Transcriptional regulator
Q433_21785	COG3192	ethanolamine utilization protein
Q433_21790	COG2079	MmgE PrpD family protein
Q433_21800	COG1126	abc transporter atp-binding protein
Q433_21805	COG0765	amino acid transport
Q433_21810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Q433_21830	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Q433_21835	COG0561	phosphatase activity
Q433_21870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Q433_21875	COG5294	Protein conserved in bacteria
Q433_21880	COG0577	efflux transmembrane transporter activity
Q433_21885	COG1136	(ABC) transporter
Q433_21890	COG2205	protein histidine kinase activity
Q433_21895	COG0745	RESPONSE REGULATOR receiver
Q433_21900	COG0191	fructose-bisphosphate aldolase activity
Q433_21905	COG1082	Xylose isomerase domain protein TIM barrel
Q433_21910	COG1082	Xylose isomerase domain protein TIM barrel
Q433_21915	COG0673	inositol 2-dehydrogenase activity
Q433_21920	COG2814	Major facilitator Superfamily
Q433_21925	COG1082	Xylose isomerase domain protein TIM barrel
Q433_21930	COG3962	Belongs to the TPP enzyme family
Q433_21935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Q433_21945	COG1012	belongs to the aldehyde dehydrogenase family
Q433_21950	COG1349	DNA-binding transcription factor activity
Q433_21955	COG0667	Aldo Keto reductase
Q433_21975	COG2814	Major facilitator Superfamily
Q433_21980	COG0326	Molecular chaperone. Has ATPase activity
Q433_21990	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_21995	COG1309	transcriptional regulator
Q433_22000	COG1012	belongs to the aldehyde dehydrogenase family
Q433_22010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Q433_22020	COG1714	RDD family
Q433_22025	COG2311	Membrane
Q433_22030	COG1917	Cupin 2, conserved barrel domain protein
Q433_22035	COG1309	transcriptional regulator
Q433_22040	COG1028	Short-chain dehydrogenase reductase Sdr
Q433_22045	COG1846	Transcriptional regulator
Q433_22050	COG1380	Effector of murein hydrolase LrgA
Q433_22055	COG1346	cytolysis
Q433_22060	COG5039	Polysaccharide pyruvyl transferase
Q433_22065	COG1929	Belongs to the glycerate kinase type-1 family
Q433_22070	COG1802	Transcriptional regulator
Q433_22075	COG1070	Carbohydrate kinase
Q433_22080	COG2610	gluconate transmembrane transporter activity
Q433_22085	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Q433_22090	COG0450	alkyl hydroperoxide reductase
Q433_22095	COG3634	alkyl hydroperoxide reductase activity
Q433_22105	COG2723	6-phospho-beta-galactosidase activity
Q433_22110	COG2190	(PTS) system
Q433_22115	COG2188	Transcriptional regulator
Q433_22125	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
Q433_22155	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Q433_22170	COG1063	alcohol dehydrogenase
Q433_22190	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
Q433_22195	COG0456	acetyltransferase
Q433_22200	COG0457	Tetratricopeptide repeat
Q433_22210	COG0010	Belongs to the arginase family
Q433_22215	COG0833	amino acid
Q433_22220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Q433_22225	COG3829	transcription factor binding
Q433_22230	COG5002	protein histidine kinase activity
Q433_22250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Q433_22255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Q433_22260	COG4853	Protein conserved in bacteria
Q433_22265	COG4863	YycH protein
Q433_22270	COG5002	protein histidine kinase activity
Q433_22275	COG0745	RESPONSE REGULATOR receiver
Q433_22305	COG0346	lactoylglutathione lyase activity
Q433_22315	COG0305	Participates in initiation and elongation during chromosome replication
Q433_22340	COG2807	transmembrane transport
Q433_22345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Q433_22350	COG0359	binds to the 23S rRNA
Q433_22355	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Q433_22360	COG4241	membrane
Q433_22375	COG5577	PFAM Coat F domain
Q433_22380	COG1733	regulation of RNA biosynthetic process
Q433_22385	COG1227	inorganic diphosphatase activity
Q433_22400	COG2271	Major facilitator Superfamily
Q433_22410	COG4978	Transcriptional regulator
Q433_22410	COG0789	Transcriptional regulator
Q433_22420	COG4319	ketosteroid isomerase
Q433_22425	COG1357	PFAM Pentapeptide repeats (8 copies)
Q433_22430	COG2814	Major facilitator Superfamily
Q433_22435	COG0583	DNA-binding transcription factor activity
Q433_22440	COG2153	protein acetylation
Q433_22450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Q433_22455	COG1846	Transcriptional regulator
Q433_22460	COG2153	protein acetylation
Q433_22465	COG2364	Membrane
Q433_22470	COG0456	acetyltransferase
Q433_22475	COG2315	Protein conserved in bacteria
Q433_22480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Q433_22490	COG2814	Major facilitator Superfamily
Q433_22495	COG1331	Highly conserved protein containing a thioredoxin domain
Q433_22500	COG1266	CAAX protease self-immunity
Q433_22505	COG0477	Major facilitator Superfamily
Q433_22505	COG2814	Major facilitator Superfamily
Q433_22510	COG0110	maltose O-acetyltransferase activity
Q433_22515	COG0346	lactoylglutathione lyase activity
Q433_22520	COG1609	Transcriptional regulator
Q433_22525	COG0708	Exodeoxyribonuclease III
Q433_22530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Q433_22535	COG0629	single-stranded DNA binding
Q433_22540	COG0360	Binds together with S18 to 16S ribosomal RNA
Q433_22545	COG0012	GTP binding
Q433_22550	COG0243	molybdopterin cofactor binding
Q433_22555	COG4481	Protein conserved in bacteria
Q433_22560	COG3949	Membrane
Q433_22570	COG1475	DNA binding
Q433_22575	COG1192	Involved in chromosome partitioning
Q433_22590	COG1475	DNA binding
Q433_22595	COG0357	Ribosomal RNA small subunit methyltransferase G
Q433_22600	COG0445	tRNA wobble uridine modification
Q433_22605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Q433_22610	COG1847	R3H domain protein
Q433_22615	COG0706	membrane insertase activity
Q433_22620	COG0594	ribonuclease P activity
Q433_22625	COG0230	Belongs to the bacterial ribosomal protein bL34 family