locus-tag	class	description
BG06_10	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG06_1000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG06_1001	COG1333	cytochrome c biogenesis protein
BG06_1003	COG1187	pseudouridine synthase activity
BG06_1004	COG0700	Nucleoside recognition
BG06_1005	COG2715	membrane protein required for spore maturation
BG06_1006	COG1686	Belongs to the peptidase S11 family
BG06_1007	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BG06_1010	COG0392	lysyltransferase activity
BG06_1010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BG06_1014	COG5002	protein histidine kinase activity
BG06_1015	COG0582	viral genome integration into host DNA
BG06_1017	COG1801	Protein of unknown function DUF72
BG06_1018	COG3852	Histidine kinase
BG06_102	COG1396	sequence-specific DNA binding
BG06_1021	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG06_1022	COG1392	Phosphate transport regulator
BG06_1023	COG0306	phosphate transporter
BG06_1024	COG0730	response to heat
BG06_1032	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BG06_1034	COG1114	Component of the transport system for branched-chain amino acids
BG06_1036	COG2197	response regulator
BG06_1037	COG4585	Histidine kinase
BG06_1038	COG4758	membrane
BG06_1041	COG1757	Na H antiporter
BG06_1047	COG0733	neurotransmitter:sodium symporter activity
BG06_1048	COG1648	precorrin-2 dehydrogenase activity
BG06_1052	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BG06_1053	COG0529	Catalyzes the synthesis of activated sulfate
BG06_1057	COG0019	diaminopimelate decarboxylase activity
BG06_1059	COG1368	sulfuric ester hydrolase activity
BG06_106	COG1132	(ABC) transporter
BG06_1060	COG1183	phosphatidylcholine synthase activity
BG06_1063	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BG06_107	COG1132	(ABC) transporter
BG06_1078	COG0440	acetolactate synthase activity
BG06_1079	COG0028	Belongs to the TPP enzyme family
BG06_1080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG06_1085	COG3874	Sporulation protein YtfJ
BG06_1086	COG4709	membrane
BG06_1087	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG06_1088	COG1301	dicarboxylic acid transport
BG06_1090	COG1846	Transcriptional regulator
BG06_1098	COG3173	Aminoglycoside phosphotransferase
BG06_11	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BG06_110	COG2258	MOSC domain
BG06_1101	COG0716	FMN binding
BG06_1106	COG1696	Membrane protein involved in D-alanine export
BG06_1108	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BG06_1109	COG2070	2-Nitropropane dioxygenase
BG06_111	COG0583	DNA-binding transcription factor activity
BG06_1110	COG1619	proteins homologs of microcin C7 resistance protein MccF
BG06_1112	COG1335	isochorismatase
BG06_1114	COG1522	sequence-specific DNA binding
BG06_1117	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BG06_1118	COG1131	(ABC) transporter
BG06_1120	COG1131	(ABC) transporter
BG06_1121	COG1725	Transcriptional regulator
BG06_1122	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG06_1123	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG06_1124	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG06_1125	COG1780	Probably involved in ribonucleotide reductase function
BG06_1131	COG4873	Protein conserved in bacteria
BG06_1134	COG0720	synthase
BG06_1136	COG5002	protein histidine kinase activity
BG06_1138	COG2318	DinB family
BG06_114	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG06_1140	COG1846	Transcriptional regulator
BG06_1141	COG3852	Histidine kinase
BG06_1143	COG2861	carbohydrate metabolic process
BG06_1145	COG0235	Class ii aldolase
BG06_1148	COG1349	DNA-binding transcription factor activity
BG06_115	COG0583	DNA-binding transcription factor activity
BG06_1151	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG06_1153	COG3842	ATPase activity
BG06_1154	COG1840	ABC-type Fe3 transport system, periplasmic component
BG06_1157	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG06_1159	COG3243	poly(R)-hydroxyalkanoic acid synthase
BG06_1160	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_1164	COG2030	dehydratase
BG06_1166	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG06_1167	COG0861	Integral membrane protein TerC family
BG06_1168	COG2116	formate transmembrane transporter activity
BG06_1170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BG06_1174	COG2186	Transcriptional regulator
BG06_1175	COG5002	protein histidine kinase activity
BG06_1176	COG0745	RESPONSE REGULATOR receiver
BG06_1178	COG3835	regulator
BG06_1179	COG0277	FAD linked oxidase domain protein
BG06_1180	COG0247	lactate metabolic process
BG06_1181	COG2340	Cysteine-rich secretory protein family
BG06_1183	COG0564	pseudouridine synthase activity
BG06_1185	COG2409	Drug exporters of the RND superfamily
BG06_1187	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BG06_1188	COG1177	transmembrane transport
BG06_1189	COG1176	ABC-type spermidine putrescine transport system, permease component I
BG06_1191	COG1012	belongs to the aldehyde dehydrogenase family
BG06_1197	COG0681	Belongs to the peptidase S26 family
BG06_1198	COG1686	Belongs to the peptidase S11 family
BG06_12	COG1024	Enoyl-CoA hydratase
BG06_1200	COG2226	methyltransferase
BG06_1209	COG1476	TRANSCRIPTIONal
BG06_1211	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG06_1215	COG2226	methyltransferase
BG06_122	COG2814	Major facilitator Superfamily
BG06_1222	COG5634	Uncharacterized conserved protein (DUF2278)
BG06_1223	COG1620	l-lactate permease
BG06_123	COG1846	Transcriptional regulator
BG06_1230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BG06_1230	COG0512	Glutamine amidotransferase of anthranilate synthase
BG06_1232	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG06_1233	COG5492	domain, Protein
BG06_1236	COG2382	esterase
BG06_1238	COG2153	protein acetylation
BG06_1246	COG1091	dTDP-4-dehydrorhamnose reductase activity
BG06_1249	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BG06_125	COG0010	Belongs to the arginase family
BG06_1253	COG0463	Glycosyl transferase, family 2
BG06_1253	COG0457	Tetratricopeptide repeat
BG06_1257	COG1216	Glycosyl transferase, family 2
BG06_1258	COG0772	Belongs to the SEDS family
BG06_1261	COG0564	pseudouridine synthase activity
BG06_1262	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BG06_1263	COG2357	RelA SpoT domain protein
BG06_1265	COG4116	CYTH
BG06_1266	COG2346	COG2346, Truncated hemoglobins
BG06_1269	COG1164	Oligoendopeptidase f
BG06_1271	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG06_1272	COG4862	establishment of competence for transformation
BG06_1273	COG0861	Integral membrane protein TerC family
BG06_1274	COG1393	Belongs to the ArsC family
BG06_1276	COG4166	transmembrane transport
BG06_1277	COG0534	Mate efflux family protein
BG06_1278	COG4608	Belongs to the ABC transporter superfamily
BG06_1279	COG0444	Belongs to the ABC transporter superfamily
BG06_128	COG1278	Cold shock
BG06_1280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG06_1281	COG0601	transmembrane transport
BG06_1282	COG4166	transmembrane transport
BG06_1284	COG0180	Tryptophanyl-tRNA synthetase
BG06_1286	COG5504	Zn-dependent protease
BG06_1287	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG06_1288	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG06_1291	COG2267	carboxylic ester hydrolase activity
BG06_1293	COG0542	response to heat
BG06_1295	COG0561	phosphatase activity
BG06_1298	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_13	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG06_130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_1300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG06_1301	COG2996	Protein conserved in bacteria
BG06_1307	COG0004	ammonium transporteR
BG06_1308	COG0753	catalase activity
BG06_1310	COG0367	asparagine synthase
BG06_1315	COG0179	Fumarylacetoacetate (FAA) hydrolase
BG06_1327	COG0398	Pfam SNARE associated Golgi protein
BG06_1330	COG2197	response regulator
BG06_1331	COG4585	Histidine kinase
BG06_1332	COG4903	ComK protein
BG06_1335	COG1278	Cold shock
BG06_1337	COG2224	Isocitrate lyase
BG06_1338	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BG06_1342	COG0697	spore germination
BG06_1343	COG0501	Belongs to the peptidase M48B family
BG06_1348	COG0745	RESPONSE REGULATOR receiver
BG06_1349	COG2205	protein histidine kinase activity
BG06_1352	COG2207	Transcriptional regulator
BG06_1352	COG3708	Transcriptional regulator
BG06_1353	COG1595	DNA-templated transcription, initiation
BG06_1355	COG1078	dGTPase activity
BG06_1356	COG1408	metallophosphoesterase
BG06_1361	COG0318	PFAM AMP-dependent synthetase and ligase
BG06_1363	COG0095	Lipoate-protein ligase
BG06_1364	COG1234	tRNA 3'-trailer cleavage
BG06_1366	COG1609	Transcriptional regulator
BG06_1367	COG2378	regulation of single-species biofilm formation
BG06_1369	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BG06_1373	COG1511	domain protein
BG06_1374	COG1309	transcriptional regulator
BG06_1382	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG06_1383	COG2329	Antibiotic biosynthesis monooxygenase
BG06_1384	COG3428	Bacterial PH domain
BG06_1385	COG3402	PFAM membrane-flanked domain
BG06_1392	COG3428	Bacterial PH domain
BG06_1393	COG3402	PFAM membrane-flanked domain
BG06_1395	COG1309	transcriptional regulator
BG06_1398	COG4473	ABC transporter
BG06_1399	COG1131	(ABC) transporter
BG06_14	COG0511	ligase activity, forming carbon-carbon bonds
BG06_1400	COG0537	adenosine 5'-monophosphoramidase activity
BG06_1401	COG4980	gas vesicle protein
BG06_1405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG06_1406	COG3973	AAA domain
BG06_1408	COG0477	Major facilitator Superfamily
BG06_1409	COG0477	Major facilitator Superfamily
BG06_1412	COG0772	Belongs to the SEDS family
BG06_1420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BG06_1422	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BG06_1423	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BG06_1430	COG2267	carboxylic ester hydrolase activity
BG06_1432	COG0457	Tetratricopeptide repeat
BG06_1433	COG0346	lactoylglutathione lyase activity
BG06_1434	COG0346	lactoylglutathione lyase activity
BG06_1437	COG4717	serine-type aminopeptidase activity
BG06_1438	COG0420	3'-5' exonuclease activity
BG06_1446	COG2205	protein histidine kinase activity
BG06_1447	COG0745	RESPONSE REGULATOR receiver
BG06_1449	COG0393	Putative heavy-metal-binding
BG06_145	COG1695	Transcriptional regulator
BG06_1454	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG06_1454	COG2198	Histidine kinase
BG06_1454	COG2205	protein histidine kinase activity
BG06_1454	COG0784	Response regulator, receiver
BG06_1455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BG06_1456	COG2208	phosphoserine phosphatase activity
BG06_1458	COG1191	sigma factor activity
BG06_147	COG0659	secondary active sulfate transmembrane transporter activity
BG06_1474	COG2770	Histidine kinase
BG06_1474	COG3437	response regulator, receiver
BG06_148	COG0589	response to stress
BG06_1481	COG2376	Dihydroxyacetone kinase
BG06_1483	COG2376	Dihydroxyacetone kinase
BG06_1488	COG1183	phosphatidylcholine synthase activity
BG06_149	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BG06_1490	COG2723	6-phospho-beta-galactosidase activity
BG06_1491	COG1263	PTS System
BG06_1491	COG2190	(PTS) system
BG06_1491	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG06_1492	COG3711	transcriptional antiterminator
BG06_15	COG0439	Biotin carboxylase
BG06_150	COG3443	Belongs to the bacterial solute-binding protein 9 family
BG06_1509	COG1404	Belongs to the peptidase S8 family
BG06_152	COG0671	phosphoesterase, PA-phosphatase related
BG06_1520	COG0305	Participates in initiation and elongation during chromosome replication
BG06_1529	COG3181	Tripartite tricarboxylate transporter family receptor
BG06_1530	COG4565	transcriptional regulatory protein
BG06_1531	COG3290	protein histidine kinase activity
BG06_1532	COG0477	Major facilitator Superfamily
BG06_1537	COG0556	nucleotide-excision repair
BG06_1541	COG1160	GTP binding
BG06_1543	COG4608	Belongs to the ABC transporter superfamily
BG06_1544	COG0444	Belongs to the ABC transporter superfamily
BG06_1545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG06_1546	COG0601	transmembrane transport
BG06_155	COG2267	carboxylic ester hydrolase activity
BG06_1551	COG1649	PFAM Uncharacterised BCR, COG1649
BG06_1558	COG0582	viral genome integration into host DNA
BG06_156	COG4990	cell redox homeostasis
BG06_157	COG2323	membrane
BG06_1573	COG1363	Peptidase, m42
BG06_1577	COG1024	Enoyl-CoA hydratase
BG06_158	COG2323	membrane
BG06_1580	COG5263	repeat protein
BG06_1580	COG4193	domain, Protein
BG06_1583	COG2244	polysaccharide biosynthetic process
BG06_1588	COG0659	secondary active sulfate transmembrane transporter activity
BG06_159	COG2323	membrane
BG06_1591	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG06_1594	COG0561	phosphatase activity
BG06_1596	COG3527	Alpha-acetolactate decarboxylase
BG06_1597	COG0028	Belongs to the TPP enzyme family
BG06_16	COG1960	acyl-CoA dehydrogenase activity
BG06_1603	COG0189	ligase activity
BG06_1606	COG1126	abc transporter atp-binding protein
BG06_1607	COG0765	amino acid transport
BG06_1608	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG06_1609	COG1132	(ABC) transporter
BG06_161	COG0730	response to heat
BG06_1610	COG1132	(ABC) transporter
BG06_1611	COG1012	belongs to the aldehyde dehydrogenase family
BG06_1613	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BG06_1614	COG0531	amino acid
BG06_1616	COG0693	protein deglycase activity
BG06_1616	COG0753	catalase activity
BG06_1617	COG0693	protein deglycase activity
BG06_1619	COG2211	Major facilitator Superfamily
BG06_1620	COG4533	DNA binding
BG06_1621	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG06_1623	COG1733	regulation of RNA biosynthetic process
BG06_1624	COG2814	Major facilitator Superfamily
BG06_1625	COG1309	transcriptional regulator
BG06_1626	COG2076	Multidrug Resistance protein
BG06_1627	COG2076	Multidrug Resistance protein
BG06_1629	COG1522	sequence-specific DNA binding
BG06_163	COG4641	Protein conserved in bacteria
BG06_1633	COG2259	Doxx family
BG06_1635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG06_1635	COG1263	PTS System
BG06_1637	COG1737	Transcriptional regulator
BG06_1639	COG0475	glutathione-regulated potassium exporter activity
BG06_1640	COG0531	amino acid
BG06_1647	COG0586	Pfam SNARE associated Golgi protein
BG06_165	COG1247	-acetyltransferase
BG06_1654	COG3546	catalase activity
BG06_1655	COG1114	Component of the transport system for branched-chain amino acids
BG06_1658	COG5522	Integral membrane protein (intg_mem_TP0381)
BG06_1660	COG1136	(ABC) transporter
BG06_1661	COG0577	efflux transmembrane transporter activity
BG06_1662	COG1388	LysM domain
BG06_1662	COG3584	3D domain protein
BG06_1666	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG06_1667	COG1447	Phosphotransferase system cellobiose-specific component IIA
BG06_1668	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG06_1668	COG3711	transcriptional antiterminator
BG06_1671	COG1283	sodium-dependent phosphate transmembrane transporter activity
BG06_1672	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG06_1673	COG1316	TRANSCRIPTIONal
BG06_1675	COG0730	response to heat
BG06_1676	COG2210	Belongs to the sulfur carrier protein TusA family
BG06_1678	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG06_1679	COG0425	Belongs to the sulfur carrier protein TusA family
BG06_1680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_1680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG06_1681	COG0425	Belongs to the sulfur carrier protein TusA family
BG06_1681	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG06_1682	COG1937	Protein conserved in bacteria
BG06_1683	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG06_1687	COG2719	SpoVR family
BG06_1688	COG0778	Nitroreductase
BG06_1695	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BG06_1696	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG06_1698	COG1609	Transcriptional regulator
BG06_1699	COG1263	PTS System
BG06_1699	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG06_1700	COG1621	beta-fructofuranosidase activity
BG06_1701	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG06_1703	COG1376	ErfK ybiS ycfS ynhG family protein
BG06_1704	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_1705	COG2252	PERMEase
BG06_1708	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG06_171	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_1710	COG1136	(ABC) transporter
BG06_1710	COG0577	efflux transmembrane transporter activity
BG06_1715	COG1846	Transcriptional regulator
BG06_1716	COG2814	Major facilitator Superfamily
BG06_1717	COG2205	protein histidine kinase activity
BG06_1724	COG0351	phosphomethylpyrimidine kinase
BG06_1725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG06_1727	COG2104	thiamine diphosphate biosynthetic process
BG06_1728	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG06_1729	COG0352	thiamine-phosphate diphosphorylase activity
BG06_1730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BG06_1731	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG06_1732	COG1116	anion transmembrane transporter activity
BG06_1733	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BG06_1737	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BG06_1762	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG06_1764	COG0581	inorganic phosphate transmembrane transporter activity
BG06_1765	COG0573	inorganic phosphate transmembrane transporter activity
BG06_1766	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BG06_1767	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BG06_1767	COG1918	ferrous iron import across plasma membrane
BG06_1768	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BG06_1769	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BG06_1771	COG0531	amino acid
BG06_1772	COG0697	spore germination
BG06_1773	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG06_1776	COG4990	cell redox homeostasis
BG06_1777	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BG06_1778	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BG06_178	COG2226	methyltransferase
BG06_1781	COG0569	domain protein
BG06_1781	COG0475	glutathione-regulated potassium exporter activity
BG06_1783	COG2153	protein acetylation
BG06_1786	COG2252	PERMEase
BG06_1787	COG1113	amino acid transport
BG06_1790	COG1114	Component of the transport system for branched-chain amino acids
BG06_1791	COG3104	oligopeptide transport
BG06_1794	COG1476	TRANSCRIPTIONal
BG06_1795	COG1388	LysM domain
BG06_1795	COG3584	3D domain protein
BG06_1796	COG0840	transmembrane signaling receptor activity
BG06_1802	COG3568	Endonuclease Exonuclease Phosphatase
BG06_1805	COG1063	alcohol dehydrogenase
BG06_1809	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BG06_1810	COG1879	ABC-type sugar transport system periplasmic component
BG06_1811	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG06_1812	COG1129	ABC transporter
BG06_1814	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG06_1815	COG1609	Transcriptional regulator
BG06_1816	COG0477	Major facilitator Superfamily
BG06_1817	COG1846	Transcriptional regulator
BG06_1818	COG2271	Major facilitator Superfamily
BG06_182	COG0596	Alpha beta hydrolase
BG06_1820	COG4608	Belongs to the ABC transporter superfamily
BG06_1821	COG0601	transmembrane transport
BG06_1823	COG4166	transmembrane transport
BG06_1826	COG0659	secondary active sulfate transmembrane transporter activity
BG06_1829	COG5002	protein histidine kinase activity
BG06_1830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BG06_1831	COG2378	regulation of single-species biofilm formation
BG06_1836	COG0833	amino acid
BG06_1837	COG0765	amino acid transport
BG06_1838	COG0765	amino acid transport
BG06_1839	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG06_184	COG1136	(ABC) transporter
BG06_1840	COG1126	abc transporter atp-binding protein
BG06_1841	COG1115	amino acid carrier protein
BG06_1842	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BG06_1844	COG0697	spore germination
BG06_1847	COG0366	Alpha amylase catalytic
BG06_1848	COG1263	PTS System
BG06_1848	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG06_1849	COG2188	Transcriptional regulator
BG06_185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BG06_1850	COG0531	amino acid
BG06_1854	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG06_1855	COG0714	Associated with various cellular activities
BG06_1856	COG4548	von Willebrand factor, type A
BG06_1858	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BG06_1859	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG06_186	COG1187	pseudouridine synthase activity
BG06_1860	COG0156	8-amino-7-oxononanoate synthase activity
BG06_1861	COG2226	methyltransferase
BG06_1863	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_1864	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_1865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_1866	COG3104	oligopeptide transport
BG06_1869	COG1620	l-lactate permease
BG06_187	COG2329	Antibiotic biosynthesis monooxygenase
BG06_1870	COG1027	Aspartate ammonia-lyase
BG06_1871	COG1253	flavin adenine dinucleotide binding
BG06_1872	COG0346	lactoylglutathione lyase activity
BG06_1873	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG06_1874	COG1316	TRANSCRIPTIONal
BG06_1877	COG2720	vancomycin resistance protein
BG06_1881	COG3227	Zinc metalloprotease (Elastase)
BG06_1884	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BG06_1885	COG2217	Heavy metal translocating P-type atpase
BG06_1886	COG0640	Transcriptional regulator
BG06_1887	COG0531	amino acid
BG06_1890	COG2427	Protein of unknown function (DUF1641)
BG06_1891	COG3383	formate dehydrogenase (NAD+) activity
BG06_1892	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BG06_1893	COG0454	-acetyltransferase
BG06_1893	COG0456	acetyltransferase
BG06_1895	COG0745	RESPONSE REGULATOR receiver
BG06_1896	COG5002	protein histidine kinase activity
BG06_1898	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_19	COG1309	transcriptional regulator
BG06_190	COG1115	amino acid carrier protein
BG06_1901	COG0281	malic enzyme
BG06_1902	COG3493	citrate carrier protein
BG06_1903	COG4565	transcriptional regulatory protein
BG06_1904	COG3290	protein histidine kinase activity
BG06_1906	COG4990	cell redox homeostasis
BG06_1908	COG5002	protein histidine kinase activity
BG06_1909	COG0745	RESPONSE REGULATOR receiver
BG06_1910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BG06_1912	COG0395	ABC-type sugar transport system, permease component
BG06_1913	COG1175	transmembrane transport
BG06_1914	COG3842	ATPase activity
BG06_1915	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BG06_1919	COG2851	Citrate transporter
BG06_192	COG2318	DinB family
BG06_1920	COG4565	transcriptional regulatory protein
BG06_1921	COG3290	protein histidine kinase activity
BG06_1923	COG2268	Band 7 protein
BG06_1924	COG1585	Membrane protein implicated in regulation of membrane protease activity
BG06_1926	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG06_1930	COG2766	serine protein kinase
BG06_1933	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BG06_1935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BG06_1937	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BG06_1938	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BG06_194	COG0776	regulation of translation
BG06_1962	COG0735	belongs to the Fur family
BG06_1963	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BG06_1967	COG4555	ABC transporter
BG06_1969	COG0067	glutamate synthase
BG06_1969	COG0069	glutamate synthase activity
BG06_1969	COG0070	glutamate synthase
BG06_197	COG2814	Major facilitator Superfamily
BG06_1970	COG4129	membrane
BG06_1971	COG1132	(ABC) transporter
BG06_1976	COG1194	a g-specific adenine glycosylase
BG06_1977	COG1988	membrane-bound metal-dependent
BG06_198	COG3251	PFAM MbtH domain protein
BG06_1983	COG1090	epimerase
BG06_1984	COG1228	amidohydrolase
BG06_1988	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BG06_199	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BG06_1991	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG06_1991	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BG06_1993	COG0463	Glycosyl transferase, family 2
BG06_1997	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BG06_1998	COG1263	PTS System
BG06_1998	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG06_1999	COG2066	Belongs to the glutaminase family
BG06_200	COG1535	isochorismatase
BG06_200	COG3433	isochorismatase activity
BG06_2004	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG06_2005	COG0833	amino acid
BG06_2007	COG3829	transcription factor binding
BG06_201	COG1021	2,3-dihydroxybenzoate-AMP ligase
BG06_2010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG06_2011	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BG06_2015	COG0535	radical SAM domain protein
BG06_2017	COG0387	Pfam Sodium calcium exchanger
BG06_2018	COG3871	stress protein (general stress protein 26)
BG06_202	COG1169	isochorismate synthase
BG06_2021	COG0586	Pfam SNARE associated Golgi protein
BG06_2026	COG0697	spore germination
BG06_2027	COG2217	Heavy metal translocating P-type atpase
BG06_2028	COG1295	ribonuclease BN
BG06_203	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_2030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BG06_2033	COG3853	Toxic anion resistance protein (TelA)
BG06_2035	COG0861	Integral membrane protein TerC family
BG06_2036	COG2310	stress, protein
BG06_2037	COG2310	stress, protein
BG06_2038	COG2310	stress, protein
BG06_204	COG2223	nitrite transmembrane transporter activity
BG06_2044	COG2270	Major facilitator Superfamily
BG06_2054	COG0488	(ABC) transporter
BG06_2056	COG1116	anion transmembrane transporter activity
BG06_2058	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG06_2061	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BG06_2067	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG06_2067	COG2190	(PTS) system
BG06_2067	COG1263	PTS System
BG06_2068	COG0366	Alpha amylase catalytic
BG06_2076	COG0840	transmembrane signaling receptor activity
BG06_2077	COG0840	transmembrane signaling receptor activity
BG06_2079	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG06_2080	COG0765	amino acid transport
BG06_2082	COG0723	plastoquinol--plastocyanin reductase activity
BG06_2082	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG06_2083	COG2814	Major facilitator Superfamily
BG06_2084	COG3541	Predicted nucleotidyltransferase
BG06_2088	COG5002	protein histidine kinase activity
BG06_2093	COG0166	Belongs to the GPI family
BG06_2096	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_2097	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_2098	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_2099	COG0235	Class ii aldolase
BG06_21	COG1131	(ABC) transporter
BG06_210	COG0419	ATPase involved in DNA repair
BG06_2101	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BG06_2102	COG0450	alkyl hydroperoxide reductase
BG06_2105	COG1473	amidohydrolase
BG06_211	COG0420	3'-5' exonuclease activity
BG06_2112	COG4807	Protein conserved in bacteria
BG06_2113	COG5002	protein histidine kinase activity
BG06_2114	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG06_2115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG06_2116	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG06_2120	COG2309	aminopeptidase activity
BG06_2121	COG2076	Multidrug Resistance protein
BG06_2122	COG1012	belongs to the aldehyde dehydrogenase family
BG06_2124	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BG06_2125	COG0546	phosphoglycolate phosphatase activity
BG06_2126	COG1597	lipid kinase activity
BG06_2130	COG4682	membrane
BG06_2131	COG1846	Transcriptional regulator
BG06_2132	COG0003	Pfam Anion-transporting ATPase
BG06_2135	COG1464	Belongs to the NlpA lipoprotein family
BG06_2136	COG2011	ABC-type metal ion transport system permease component
BG06_2138	COG1335	isochorismatase
BG06_214	COG1024	Enoyl-CoA hydratase
BG06_2142	COG4851	CamS sex pheromone cAM373 precursor
BG06_2144	COG0210	DNA helicase
BG06_2149	COG0151	Belongs to the GarS family
BG06_215	COG1280	lysine exporter protein (LysE YggA)
BG06_2151	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BG06_2153	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BG06_2156	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BG06_2158	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BG06_2159	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BG06_216	COG1012	belongs to the aldehyde dehydrogenase family
BG06_2160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BG06_2166	COG0697	spore germination
BG06_217	COG2084	Dehydrogenase
BG06_2171	COG0745	RESPONSE REGULATOR receiver
BG06_2172	COG2205	protein histidine kinase activity
BG06_218	COG1960	acyl-CoA dehydrogenase activity
BG06_2185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BG06_219	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BG06_2190	COG5002	protein histidine kinase activity
BG06_2192	COG2252	PERMEase
BG06_2196	COG1266	CAAX protease self-immunity
BG06_2199	COG0488	(ABC) transporter
BG06_220	COG2079	MmgE PrpD family protein
BG06_2201	COG0456	acetyltransferase
BG06_2202	COG1214	PFAM Peptidase M22, glycoprotease
BG06_2203	COG0802	atpase or kinase
BG06_221	COG0372	Belongs to the citrate synthase family
BG06_222	COG4841	protein insertion into membrane
BG06_2222	COG2183	response to ionizing radiation
BG06_2223	COG2337	Toxic component of a toxin-antitoxin (TA) module
BG06_2224	COG0864	Transcriptional regulator
BG06_2225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG06_2226	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BG06_2228	COG4294	response to UV
BG06_2229	COG0705	Rhomboid family
BG06_2229	COG0457	Tetratricopeptide repeat
BG06_223	COG2814	Major facilitator Superfamily
BG06_2231	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BG06_2233	COG2814	Major facilitator Superfamily
BG06_2235	COG0179	Fumarylacetoacetate (FAA) hydrolase
BG06_2236	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BG06_224	COG4499	WXG100 protein secretion system (Wss), protein YukC
BG06_224	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG06_2241	COG0561	phosphatase activity
BG06_2242	COG4608	Belongs to the ABC transporter superfamily
BG06_2243	COG0444	Belongs to the ABC transporter superfamily
BG06_2244	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG06_2245	COG0601	transmembrane transport
BG06_2246	COG0747	negative chemotaxis
BG06_2249	COG0488	(ABC) transporter
BG06_2252	COG5298	Protein conserved in bacteria
BG06_2254	COG0084	hydrolase, TatD family'
BG06_2257	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_2259	COG1609	Transcriptional regulator
BG06_2261	COG0204	Acyl-transferase
BG06_2264	COG0697	spore germination
BG06_2268	COG1910	domain protein
BG06_2269	COG0725	ABC transporter, periplasmic molybdate-binding protein
BG06_2270	COG4149	molybdate abc transporter
BG06_2273	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG06_2274	COG0656	L-ascorbic acid biosynthetic process
BG06_2275	COG4166	transmembrane transport
BG06_2276	COG4166	transmembrane transport
BG06_2278	COG1309	transcriptional regulator
BG06_2280	COG2207	Transcriptional regulator
BG06_2282	COG4166	transmembrane transport
BG06_2283	COG4608	Belongs to the ABC transporter superfamily
BG06_2284	COG0444	Belongs to the ABC transporter superfamily
BG06_2285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG06_2286	COG0601	transmembrane transport
BG06_2289	COG2814	Major facilitator Superfamily
BG06_2291	COG2271	Major facilitator Superfamily
BG06_2292	COG0277	FAD linked oxidase domain protein
BG06_2295	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_2299	COG1506	peptidase
BG06_2299	COG0823	Involved in the tonB-independent uptake of proteins
BG06_2299	COG4946	Tricorn protease homolog
BG06_2300	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BG06_2304	COG0596	Alpha beta hydrolase
BG06_2308	COG4856	YbbR-like protein
BG06_2309	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BG06_232	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG06_2326	COG0726	polysaccharide deacetylase
BG06_2327	COG2194	sulfuric ester hydrolase activity
BG06_2329	COG0489	protein tyrosine kinase activity
BG06_2330	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG06_2334	COG0101	tRNA pseudouridine synthase activity
BG06_2335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BG06_2336	COG1122	ATPase activity
BG06_2342	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BG06_2344	COG0024	Methionine aminopeptidase
BG06_2346	COG0201	protein transport
BG06_2351	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BG06_2372	COG1358	cellular component organization or biogenesis
BG06_2375	COG2813	Specifically methylates the guanine in position
BG06_2380	COG0250	Participates in transcription elongation, termination and antitermination
BG06_2381	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG06_2383	COG3688	RNA-binding protein containing a PIN domain
BG06_2384	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG06_2387	COG1045	serine acetyltransferase
BG06_2391	COG4956	integral membrane protein (PIN domain superfamily)
BG06_2393	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BG06_2394	COG0542	response to heat
BG06_2396	COG3880	PFAM UvrB UvrC protein
BG06_24	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG06_2416	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG06_2417	COG1396	sequence-specific DNA binding
BG06_2418	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BG06_2419	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BG06_2420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BG06_2421	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG06_2422	COG0512	Glutamine amidotransferase of anthranilate synthase
BG06_2423	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BG06_2424	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG06_2427	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BG06_2430	COG2208	phosphoserine phosphatase activity
BG06_2433	COG1098	S1 RNA binding domain
BG06_2437	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BG06_2438	COG3956	TIGRFAM MazG family protein
BG06_2439	COG2244	polysaccharide biosynthetic process
BG06_2440	COG2002	toxin-antitoxin pair type II binding
BG06_2441	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BG06_2443	COG0193	aminoacyl-tRNA hydrolase activity
BG06_2444	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BG06_2447	COG0251	oxidation-reduction process
BG06_2448	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BG06_2451	COG4466	Protein conserved in bacteria
BG06_2454	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BG06_2455	COG0084	hydrolase, TatD family'
BG06_2456	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG06_2456	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG06_2457	COG2002	toxin-antitoxin pair type II binding
BG06_2458	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BG06_2460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BG06_2462	COG1774	PSP1 C-terminal conserved region
BG06_2463	COG0470	DNA polymerase III
BG06_2465	COG1982	Orn Lys Arg decarboxylase major
BG06_2477	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BG06_2478	COG0590	tRNA wobble adenosine to inosine editing
BG06_2479	COG1335	isochorismatase
BG06_248	COG1715	Restriction endonuclease
BG06_248	COG1787	Restriction endonuclease
BG06_2480	COG1428	Deoxynucleoside kinase
BG06_2481	COG1428	Deoxynucleoside kinase
BG06_2487	COG1686	Belongs to the peptidase S11 family
BG06_2488	COG0516	GMP reductase activity
BG06_2488	COG0517	IMP dehydrogenase activity
BG06_2496	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG06_2497	COG0187	DNA topoisomerase II activity
BG06_2499	COG2501	S4 domain
BG06_2500	COG0592	DNA-directed DNA polymerase activity
BG06_2504	COG0706	membrane insertase activity
BG06_2505	COG1847	R3H domain protein
BG06_2506	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BG06_2510	COG1192	Involved in chromosome partitioning
BG06_2511	COG1475	DNA binding
BG06_2513	COG0668	transmembrane transport
BG06_2514	COG4481	Protein conserved in bacteria
BG06_2515	COG0012	GTP binding
BG06_2517	COG0629	single-stranded DNA binding
BG06_2519	COG4241	membrane
BG06_2520	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BG06_2522	COG0305	Participates in initiation and elongation during chromosome replication
BG06_2528	COG0745	RESPONSE REGULATOR receiver
BG06_2529	COG5002	protein histidine kinase activity
BG06_2530	COG4863	YycH protein
BG06_2531	COG4853	Protein conserved in bacteria
BG06_2532	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BG06_2533	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG06_2537	COG1164	Oligoendopeptidase f
BG06_2543	COG1272	protein, Hemolysin III
BG06_2544	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BG06_2548	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BG06_2549	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BG06_255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG06_2550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG06_2551	COG2814	Major facilitator Superfamily
BG06_2552	COG3275	phosphorelay sensor kinase activity
BG06_2553	COG3279	Response regulator of the LytR AlgR family
BG06_2556	COG0628	permease
BG06_2559	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG06_2559	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG06_256	COG0671	phosphoesterase, PA-phosphatase related
BG06_2560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG06_2561	COG1309	transcriptional regulator
BG06_2562	COG0463	Glycosyl transferase, family 2
BG06_2566	COG0488	(ABC) transporter
BG06_2568	COG1216	Glycosyl transferase, family 2
BG06_2569	COG1607	acyl-coa hydrolase
BG06_257	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BG06_2571	COG0840	transmembrane signaling receptor activity
BG06_2576	COG0477	Major facilitator Superfamily
BG06_2577	COG3279	Response regulator of the LytR AlgR family
BG06_2578	COG1966	Carbon starvation protein
BG06_2579	COG2879	small protein
BG06_258	COG4326	sporulation control protein
BG06_2580	COG3706	GGDEF domain
BG06_2581	COG0351	phosphomethylpyrimidine kinase
BG06_2582	COG2203	Gaf domain
BG06_2582	COG4585	Histidine kinase
BG06_2583	COG2197	response regulator
BG06_2585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG06_2586	COG1011	Hydrolase
BG06_2589	COG0460	homoserine dehydrogenase
BG06_2591	COG1609	Transcriptional regulator
BG06_2592	COG2755	lipolytic protein G-D-S-L family
BG06_2593	COG1131	(ABC) transporter
BG06_2594	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BG06_2596	COG2814	Major facilitator Superfamily
BG06_2597	COG0561	phosphatase activity
BG06_2598	COG2233	PERMEase
BG06_2599	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BG06_2601	COG2363	Small membrane protein
BG06_2603	COG3773	Cell wall hydrolase
BG06_2606	COG0280	phosphate acetyltransferase
BG06_2607	COG0095	Lipoate-protein ligase
BG06_2611	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_2612	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_2613	COG1120	ATPase activity
BG06_2614	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_2615	COG1078	dGTPase activity
BG06_2617	COG1994	Peptidase M50
BG06_2619	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG06_2620	COG0584	glycerophosphoryl diester phosphodiesterase
BG06_2621	COG0789	Transcriptional regulator
BG06_2622	COG2814	Major facilitator Superfamily
BG06_2623	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BG06_2624	COG0010	Belongs to the arginase family
BG06_2627	COG1619	proteins homologs of microcin C7 resistance protein MccF
BG06_2628	COG4506	Protein conserved in bacteria
BG06_2630	COG1595	DNA-templated transcription, initiation
BG06_2634	COG2234	aminopeptidase activity
BG06_2636	COG0024	Methionine aminopeptidase
BG06_2637	COG1131	(ABC) transporter
BG06_2638	COG0842	Transport permease protein
BG06_2639	COG4585	Histidine kinase
BG06_2640	COG2197	response regulator
BG06_2643	COG3300	MHYT domain
BG06_2643	COG5001	Diguanylate cyclase
BG06_2645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG06_2646	COG2181	nitrate reductase activity
BG06_2646	COG0247	lactate metabolic process
BG06_2647	COG0183	Belongs to the thiolase family
BG06_2648	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG06_2649	COG1960	acyl-CoA dehydrogenase activity
BG06_2650	COG1960	acyl-CoA dehydrogenase activity
BG06_2654	COG4821	SIS domain
BG06_2657	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BG06_2658	COG1494	fructose-1,6-bisphosphatase
BG06_2659	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BG06_266	COG1509	lysine 2,3-aminomutase activity
BG06_2662	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BG06_2663	COG2890	protein-(glutamine-N5) methyltransferase activity
BG06_2666	COG0009	L-threonylcarbamoyladenylate synthase
BG06_267	COG3829	transcription factor binding
BG06_2671	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BG06_2672	COG2259	Doxx family
BG06_2673	COG2190	(PTS) system
BG06_2675	COG0698	ribose 5-phosphate isomerase
BG06_268	COG0456	acetyltransferase
BG06_2681	COG0356	it plays a direct role in the translocation of protons across the membrane
BG06_269	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG06_2691	COG3300	MHYT domain
BG06_2691	COG5001	Diguanylate cyclase
BG06_2694	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BG06_2698	COG0839	Belongs to the complex I subunit 6 family
BG06_270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BG06_2700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BG06_2702	COG1007	ATP synthesis coupled electron transport
BG06_2703	COG4836	Membrane
BG06_2706	COG2385	sporulation resulting in formation of a cellular spore
BG06_2707	COG3279	Response regulator of the LytR AlgR family
BG06_271	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BG06_2710	COG0739	heme binding
BG06_2711	COG1609	Transcriptional regulator
BG06_2714	COG0489	protein tyrosine kinase activity
BG06_2715	COG3944	biosynthesis protein
BG06_2716	COG0489	protein tyrosine kinase activity
BG06_2717	COG4464	protein tyrosine phosphatase activity
BG06_2718	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BG06_2719	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG06_272	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG06_2723	COG0728	peptidoglycan biosynthetic process
BG06_2725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BG06_2726	COG1045	serine acetyltransferase
BG06_2729	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BG06_2730	COG0745	RESPONSE REGULATOR receiver
BG06_2731	COG5002	protein histidine kinase activity
BG06_2738	COG1136	(ABC) transporter
BG06_2739	COG0577	efflux transmembrane transporter activity
BG06_2742	COG1191	sigma factor activity
BG06_2748	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BG06_2749	COG4715	Zinc finger, swim domain protein
BG06_275	COG5506	Protein of unknown function (DUF1694)
BG06_2754	COG1388	LysM domain
BG06_2754	COG3584	3D domain protein
BG06_2755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG06_2757	COG1215	transferase activity, transferring glycosyl groups
BG06_2759	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG06_276	COG1012	belongs to the aldehyde dehydrogenase family
BG06_2760	COG0791	NLP P60 protein
BG06_2760	COG1388	LysM domain
BG06_2762	COG1368	sulfuric ester hydrolase activity
BG06_2764	COG2389	metal-binding protein
BG06_2766	COG1620	l-lactate permease
BG06_2768	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG06_2769	COG1294	oxidase, subunit
BG06_277	COG1253	flavin adenine dinucleotide binding
BG06_2770	COG1271	oxidase subunit
BG06_2774	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BG06_2775	COG0583	DNA-binding transcription factor activity
BG06_2776	COG1511	domain protein
BG06_2777	COG0346	lactoylglutathione lyase activity
BG06_2779	COG1301	dicarboxylic acid transport
BG06_2780	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG06_2782	COG1447	Phosphotransferase system cellobiose-specific component IIA
BG06_2786	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BG06_2788	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG06_2789	COG1447	Phosphotransferase system cellobiose-specific component IIA
BG06_2790	COG1486	melibiose metabolic process
BG06_2794	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BG06_2794	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BG06_2796	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG06_2797	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BG06_2798	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BG06_2799	COG1316	TRANSCRIPTIONal
BG06_2800	COG1739	Uncharacterized protein family UPF0029
BG06_2801	COG1307	EDD domain protein, DegV family
BG06_2802	COG1733	regulation of RNA biosynthetic process
BG06_2803	COG0791	NLP P60 protein
BG06_2803	COG1388	LysM domain
BG06_2804	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BG06_2805	COG1040	competence protein
BG06_2806	COG1278	Cold shock
BG06_2807	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BG06_2809	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BG06_2812	COG2884	Cell division ATP-binding protein ftsE
BG06_2813	COG2177	Part of the ABC transporter FtsEX involved in
BG06_2814	COG0793	Belongs to the peptidase S41A family
BG06_2814	COG3409	Peptidoglycan-binding domain 1 protein
BG06_2815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG06_2816	COG1132	(ABC) transporter
BG06_2819	COG0655	NAD(P)H dehydrogenase (quinone) activity
BG06_2821	COG0583	DNA-binding transcription factor activity
BG06_2822	COG2855	membrane
BG06_2828	COG0789	Transcriptional regulator
BG06_2832	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG06_2834	COG1950	PFAM Membrane protein of
BG06_2838	COG0110	maltose O-acetyltransferase activity
BG06_2839	COG0457	Tetratricopeptide repeat
BG06_284	COG1174	glycine betaine transport
BG06_2840	COG0492	ferredoxin-NADP+ reductase activity
BG06_2842	COG1051	belongs to the nudix hydrolase family
BG06_2844	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BG06_2846	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG06_2848	COG2323	membrane
BG06_285	COG0517	IMP dehydrogenase activity
BG06_285	COG1125	glycine betaine transport
BG06_2851	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG06_2856	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BG06_2859	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG06_2866	COG1346	cytolysis
BG06_2867	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG06_2868	COG1647	Serine aminopeptidase, S33
BG06_2869	COG0557	exoribonuclease II activity
BG06_2872	COG2311	Membrane
BG06_2873	COG3963	phosphatidate phosphatase activity
BG06_2874	COG0586	Pfam SNARE associated Golgi protein
BG06_2878	COG1136	(ABC) transporter
BG06_2887	COG3223	Belongs to the PsiE family
BG06_2888	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_2894	COG0840	transmembrane signaling receptor activity
BG06_2894	COG3290	protein histidine kinase activity
BG06_2900	COG1252	NADH dehydrogenase
BG06_2902	COG1733	regulation of RNA biosynthetic process
BG06_2903	COG2814	Major facilitator Superfamily
BG06_2904	COG0656	L-ascorbic acid biosynthetic process
BG06_2907	COG2910	NAD(P)H-binding
BG06_2908	COG1115	amino acid carrier protein
BG06_2909	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG06_2910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG06_2914	COG1611	Belongs to the LOG family
BG06_2917	COG0783	Belongs to the Dps family
BG06_2918	COG1115	amino acid carrier protein
BG06_2919	COG0490	domain, Protein
BG06_292	COG1070	Carbohydrate kinase
BG06_2920	COG0475	glutathione-regulated potassium exporter activity
BG06_2923	COG1741	Belongs to the pirin family
BG06_2924	COG3227	Zinc metalloprotease (Elastase)
BG06_2925	COG2151	metal-sulfur cluster biosynthetic enzyme
BG06_2926	COG0840	transmembrane signaling receptor activity
BG06_2931	COG5002	protein histidine kinase activity
BG06_2932	COG0745	RESPONSE REGULATOR receiver
BG06_2933	COG1376	ErfK ybiS ycfS ynhG family protein
BG06_2935	COG0586	Pfam SNARE associated Golgi protein
BG06_2943	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_2945	COG0706	membrane insertase activity
BG06_2947	COG0531	amino acid
BG06_2948	COG2814	Major facilitator Superfamily
BG06_2952	COG0840	transmembrane signaling receptor activity
BG06_2953	COG0011	TIGRFAM Protein of
BG06_2956	COG1686	Belongs to the peptidase S11 family
BG06_2958	COG1024	Enoyl-CoA hydratase
BG06_2958	COG1250	3-hydroxyacyl-CoA dehydrogenase
BG06_2959	COG0183	Belongs to the thiolase family
BG06_2960	COG1960	acyl-CoA dehydrogenase activity
BG06_2961	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_2962	COG1309	transcriptional regulator
BG06_297	COG1064	alcohol dehydrogenase
BG06_2977	COG1393	Belongs to the ArsC family
BG06_2979	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BG06_298	COG1737	Transcriptional regulator
BG06_2980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG06_2983	COG2011	ABC-type metal ion transport system permease component
BG06_2984	COG1464	Belongs to the NlpA lipoprotein family
BG06_2985	COG1464	Belongs to the NlpA lipoprotein family
BG06_2986	COG0396	ATPase activity
BG06_2987	COG0719	Fe-S assembly protein
BG06_2988	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BG06_2989	COG0822	iron-sulfur transferase activity
BG06_2990	COG0719	Fe-S assembly protein
BG06_2991	COG0737	Belongs to the 5'-nucleotidase family
BG06_2992	COG3377	Domain of unknown function (DUF1805)
BG06_2994	COG0739	heme binding
BG06_2999	COG4377	Putative membrane peptidase family (DUF2324)
BG06_30	COG1309	transcriptional regulator
BG06_300	COG2197	response regulator
BG06_3000	COG0789	Transcriptional regulator
BG06_3002	COG4470	Protein conserved in bacteria
BG06_3006	COG1494	fructose-1,6-bisphosphatase
BG06_3007	COG2445	Protein of unknown function DUF86
BG06_3009	COG0647	UMP catabolic process
BG06_301	COG4585	Histidine kinase
BG06_301	COG2203	Gaf domain
BG06_3011	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG06_3012	COG0577	efflux transmembrane transporter activity
BG06_3012	COG1136	(ABC) transporter
BG06_3015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BG06_3016	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BG06_3018	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BG06_3019	COG4837	Protein of unknown function (DUF1462)
BG06_302	COG0668	transmembrane transport
BG06_3023	COG2824	Alkylphosphonate utilization operon protein PhnA
BG06_3024	COG0390	transport system, permease component
BG06_3025	COG2274	protein secretion by the type I secretion system
BG06_3026	COG1252	NADH dehydrogenase
BG06_3029	COG0316	Belongs to the HesB IscA family
BG06_303	COG0071	Belongs to the small heat shock protein (HSP20) family
BG06_3031	COG1683	Conserved Protein
BG06_3034	COG3708	Transcriptional regulator
BG06_3037	COG1252	NADH dehydrogenase
BG06_304	COG1051	belongs to the nudix hydrolase family
BG06_3040	COG3584	3D domain protein
BG06_3043	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG06_3044	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BG06_3047	COG1268	BioY protein
BG06_3049	COG2050	protein possibly involved in aromatic compounds catabolism
BG06_305	COG1335	isochorismatase
BG06_3053	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG06_3054	COG5018	Exonuclease
BG06_3058	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BG06_3060	COG2267	carboxylic ester hydrolase activity
BG06_3061	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG06_3062	COG1522	sequence-specific DNA binding
BG06_3063	COG0436	Aminotransferase
BG06_3064	COG1098	S1 RNA binding domain
BG06_3065	COG2155	Conserved Protein
BG06_3067	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BG06_3069	COG1285	pathogenesis
BG06_3077	COG0544	peptidyl-prolyl cis-trans isomerase activity
BG06_309	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG06_3096	COG1595	DNA-templated transcription, initiation
BG06_3098	COG0039	L-malate dehydrogenase activity
BG06_310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_3101	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BG06_3102	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BG06_3104	COG0058	SHG alpha-glucan phosphorylase activity
BG06_3108	COG1278	Cold shock
BG06_3109	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BG06_3110	COG1575	Belongs to the MenA family. Type 1 subfamily
BG06_3111	COG1169	isochorismate synthase
BG06_3113	COG0596	Alpha beta hydrolase
BG06_3114	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BG06_3116	COG4948	Mandelate Racemase Muconate Lactonizing
BG06_3120	COG3964	amidohydrolase
BG06_3128	COG0577	efflux transmembrane transporter activity
BG06_3129	COG1136	(ABC) transporter
BG06_3130	COG0577	efflux transmembrane transporter activity
BG06_3131	COG0577	efflux transmembrane transporter activity
BG06_3132	COG2205	protein histidine kinase activity
BG06_3133	COG0745	RESPONSE REGULATOR receiver
BG06_3134	COG3708	Transcriptional regulator
BG06_3134	COG2207	Transcriptional regulator
BG06_3135	COG1136	(ABC) transporter
BG06_3136	COG0577	efflux transmembrane transporter activity
BG06_314	COG0367	asparagine synthase
BG06_3140	COG0586	Pfam SNARE associated Golgi protein
BG06_3143	COG1136	(ABC) transporter
BG06_3144	COG0577	efflux transmembrane transporter activity
BG06_3148	COG1597	lipid kinase activity
BG06_315	COG0071	Belongs to the small heat shock protein (HSP20) family
BG06_3154	COG0745	RESPONSE REGULATOR receiver
BG06_3155	COG5002	protein histidine kinase activity
BG06_316	COG1999	signal sequence binding
BG06_3160	COG1842	Phage shock protein A
BG06_3165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_317	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BG06_3171	COG1294	oxidase, subunit
BG06_3172	COG1271	oxidase subunit
BG06_3174	COG0288	reversible hydration of carbon dioxide
BG06_3179	COG0494	nUDIX hydrolase
BG06_318	COG1307	EDD domain protein, DegV family
BG06_3184	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG06_3185	COG1116	anion transmembrane transporter activity
BG06_3186	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BG06_3189	COG1368	sulfuric ester hydrolase activity
BG06_3190	COG2267	carboxylic ester hydrolase activity
BG06_3191	COG4191	Histidine kinase
BG06_3192	COG5002	protein histidine kinase activity
BG06_3193	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BG06_320	COG0805	protein transport
BG06_3201	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_3203	COG0521	Mo-molybdopterin cofactor biosynthetic process
BG06_3205	COG0438	transferase activity, transferring glycosyl groups
BG06_3206	COG0671	phosphoesterase, PA-phosphatase related
BG06_3207	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BG06_3208	COG2267	carboxylic ester hydrolase activity
BG06_3213	COG5504	Zn-dependent protease
BG06_3215	COG1794	racemase activity, acting on amino acids and derivatives
BG06_3218	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BG06_3219	COG1242	4 iron, 4 sulfur cluster binding
BG06_322	COG1272	protein, Hemolysin III
BG06_3223	COG1136	(ABC) transporter
BG06_3225	COG0582	viral genome integration into host DNA
BG06_3226	COG0490	domain, Protein
BG06_3227	COG0475	glutathione-regulated potassium exporter activity
BG06_3228	COG2814	Major facilitator Superfamily
BG06_323	COG0204	Acyl-transferase
BG06_3236	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG06_3238	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG06_3242	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BG06_3243	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG06_3245	COG0303	'Molybdopterin
BG06_3246	COG1763	Mo-molybdopterin cofactor biosynthetic process
BG06_3247	COG0314	molybdopterin synthase activity
BG06_3252	COG1329	Transcriptional regulator
BG06_3256	COG3832	glyoxalase III activity
BG06_3258	COG2814	Major facilitator Superfamily
BG06_3259	COG2081	HI0933 family
BG06_3260	COG2244	polysaccharide biosynthetic process
BG06_3261	COG1187	pseudouridine synthase activity
BG06_3262	COG1349	DNA-binding transcription factor activity
BG06_3263	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG06_3265	COG1523	belongs to the glycosyl hydrolase 13 family
BG06_3266	COG0510	thiamine kinase activity
BG06_3269	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_327	COG0768	penicillin binding
BG06_3271	COG1363	Peptidase, m42
BG06_3272	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BG06_3273	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG06_3275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG06_3277	COG1674	ftsk spoiiie
BG06_3277	COG1674	ftsk spoiiie
BG06_3281	COG1695	Transcriptional regulator
BG06_3282	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_3285	COG2309	aminopeptidase activity
BG06_3287	COG3118	belongs to the thioredoxin family
BG06_3288	COG4851	CamS sex pheromone cAM373 precursor
BG06_3289	COG1609	Transcriptional regulator
BG06_3296	COG0666	response to abiotic stimulus
BG06_3298	COG0745	RESPONSE REGULATOR receiver
BG06_3301	COG0123	including yeast histone deacetylase and acetoin utilization protein
BG06_3302	COG0517	IMP dehydrogenase activity
BG06_3303	COG0454	-acetyltransferase
BG06_3304	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG06_3307	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BG06_331	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BG06_3311	COG0626	cystathionine gamma-synthase activity
BG06_3312	COG1956	GAF domain-containing protein
BG06_3313	COG1309	transcriptional regulator
BG06_3314	COG0697	spore germination
BG06_3315	COG0583	DNA-binding transcription factor activity
BG06_3317	COG1104	cysteine desulfurase activity
BG06_3320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG06_3322	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BG06_3323	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BG06_3325	COG3874	Sporulation protein YtfJ
BG06_3326	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BG06_3327	COG0827	DNA restriction-modification system
BG06_3332	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_334	COG0546	phosphoglycolate phosphatase activity
BG06_3341	COG0589	response to stress
BG06_3342	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_3345	COG0662	Cupin 2, conserved barrel domain protein
BG06_3346	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_3356	COG0006	proline dipeptidase activity
BG06_3359	COG4109	DRTGG domain
BG06_336	COG4473	ABC transporter
BG06_3361	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BG06_3364	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BG06_3367	COG0587	DNA-directed DNA polymerase activity
BG06_3368	COG0281	malic enzyme
BG06_3369	COG1725	Transcriptional regulator
BG06_337	COG1131	(ABC) transporter
BG06_3374	COG3030	protein affecting phage T7 exclusion by the F plasmid
BG06_3375	COG0628	permease
BG06_3377	COG0372	Belongs to the citrate synthase family
BG06_3378	COG0538	isocitrate dehydrogenase activity
BG06_3383	COG0745	RESPONSE REGULATOR receiver
BG06_3384	COG5002	protein histidine kinase activity
BG06_3385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG06_3385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG06_3386	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BG06_3387	COG1971	Probably functions as a manganese efflux pump
BG06_3389	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG06_339	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG06_3390	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BG06_3392	COG3611	Membrane attachment protein
BG06_3393	COG1484	DNA-dependent DNA replication
BG06_3395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BG06_3396	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BG06_34	COG1876	peptidase activity
BG06_340	COG0456	acetyltransferase
BG06_3400	COG1363	Peptidase, m42
BG06_3401	COG1309	transcriptional regulator
BG06_3402	COG1566	PFAM secretion protein HlyD family protein
BG06_3403	COG2814	Major facilitator Superfamily
BG06_3405	COG1418	mRNA catabolic process
BG06_3407	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG06_3409	COG0072	phenylalanine-tRNA ligase activity
BG06_3409	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG06_3416	COG1286	toxin biosynthetic process
BG06_3417	COG1796	DNA polymerase
BG06_3417	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BG06_342	COG1794	racemase activity, acting on amino acids and derivatives
BG06_3420	COG1187	pseudouridine synthase activity
BG06_3421	COG1114	Component of the transport system for branched-chain amino acids
BG06_3422	COG5386	Cell surface protein
BG06_3423	COG5386	Cell surface protein
BG06_3426	COG1120	ATPase activity
BG06_3427	COG4509	Sortase family
BG06_343	COG1454	alcohol dehydrogenase
BG06_3430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BG06_3431	COG4895	conserved protein (DUF2196)
BG06_3433	COG0745	RESPONSE REGULATOR receiver
BG06_3434	COG2205	protein histidine kinase activity
BG06_3435	COG1131	(ABC) transporter
BG06_344	COG2610	gluconate transmembrane transporter activity
BG06_3440	COG2318	DinB family
BG06_3444	COG0318	PFAM AMP-dependent synthetase and ligase
BG06_3445	COG1309	transcriptional regulator
BG06_3446	COG1024	Enoyl-CoA hydratase
BG06_3447	COG2086	electron transfer activity
BG06_3448	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BG06_3449	COG3118	belongs to the thioredoxin family
BG06_3451	COG1719	4-vinyl reductase, 4VR
BG06_3452	COG2009	succinate dehydrogenase
BG06_3453	COG1053	succinate dehydrogenase
BG06_3454	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BG06_3455	COG0824	Thioesterase
BG06_3456	COG1876	peptidase activity
BG06_3457	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BG06_3458	COG1360	Flagellar Motor Protein
BG06_3459	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BG06_3460	COG4152	abc transporter atp-binding protein
BG06_3461	COG1668	transmembrane transport
BG06_3462	COG1959	2 iron, 2 sulfur cluster binding
BG06_3464	COG0697	spore germination
BG06_3465	COG1396	sequence-specific DNA binding
BG06_3466	COG1983	PspC domain protein
BG06_3468	COG3279	Response regulator of the LytR AlgR family
BG06_3469	COG3275	phosphorelay sensor kinase activity
BG06_3470	COG4608	Belongs to the ABC transporter superfamily
BG06_3471	COG0444	Belongs to the ABC transporter superfamily
BG06_3475	COG0402	S-adenosylhomocysteine deaminase activity
BG06_3476	COG0402	S-adenosylhomocysteine deaminase activity
BG06_3478	COG2233	PERMEase
BG06_3479	COG2197	response regulator
BG06_3482	COG1309	transcriptional regulator
BG06_3486	COG5401	PFAM Sporulation and spore germination
BG06_3488	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BG06_3489	COG0622	Phosphoesterase
BG06_349	COG0733	neurotransmitter:sodium symporter activity
BG06_3493	COG0457	Tetratricopeptide repeat
BG06_350	COG0017	Asparaginyl-tRNA synthetase
BG06_3504	COG1067	ATP-dependent peptidase activity
BG06_3504	COG0470	DNA polymerase III
BG06_3507	COG1764	response to oxidative stress
BG06_3508	COG1846	Transcriptional regulator
BG06_351	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BG06_3510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG06_3512	COG1587	Uroporphyrinogen-III synthase
BG06_3513	COG0113	porphobilinogen synthase activity
BG06_3515	COG1388	LysM domain
BG06_3518	COG0285	dihydrofolate synthase activity
BG06_3522	COG1077	Cell shape determining protein MreB Mrl
BG06_3523	COG1792	Involved in formation and maintenance of cell shape
BG06_3526	COG2894	cell division
BG06_3527	COG0739	heme binding
BG06_3528	COG1994	Peptidase M50
BG06_3529	COG1530	ribonuclease E activity
BG06_3531	COG2868	ribosomal protein
BG06_3533	COG3290	protein histidine kinase activity
BG06_3535	COG0745	RESPONSE REGULATOR receiver
BG06_3536	COG5002	protein histidine kinase activity
BG06_3537	COG1136	(ABC) transporter
BG06_3538	COG0577	efflux transmembrane transporter activity
BG06_3539	COG0577	efflux transmembrane transporter activity
BG06_3540	COG0077	Prephenate dehydratase
BG06_3541	COG2258	MOSC domain
BG06_3542	COG1827	regulation of RNA biosynthetic process
BG06_3543	COG1104	cysteine desulfurase activity
BG06_3544	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BG06_3545	COG0157	Belongs to the NadC ModD family
BG06_3550	COG0640	Transcriptional regulator
BG06_3551	COG0697	spore germination
BG06_3553	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BG06_3559	COG1862	Preprotein translocase
BG06_3561	COG2323	membrane
BG06_3562	COG2244	polysaccharide biosynthetic process
BG06_3564	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG06_3564	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG06_3565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BG06_3566	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BG06_3566	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BG06_3568	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG06_3571	COG0124	histidyl-tRNA synthetase
BG06_3573	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BG06_3575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BG06_3576	COG1959	2 iron, 2 sulfur cluster binding
BG06_3577	COG1104	cysteine desulfurase activity
BG06_358	COG2521	methyltransferase
BG06_358	COG2136	Putative SAM-dependent methyltransferase
BG06_3580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BG06_3584	COG0628	permease
BG06_3590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BG06_3596	COG0768	penicillin binding
BG06_3601	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG06_3602	COG0626	cystathionine gamma-synthase activity
BG06_3603	COG1454	alcohol dehydrogenase
BG06_3603	COG1012	belongs to the aldehyde dehydrogenase family
BG06_3605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_361	COG1413	lyase activity
BG06_3613	COG2259	Doxx family
BG06_3614	COG2514	catechol 2,3-dioxygenase activity
BG06_3616	COG3186	Phenylalanine-4-hydroxylase
BG06_3617	COG1404	Belongs to the peptidase S8 family
BG06_3624	COG2267	carboxylic ester hydrolase activity
BG06_3626	COG1785	Belongs to the alkaline phosphatase family
BG06_3628	COG2357	RelA SpoT domain protein
BG06_3629	COG0778	Nitroreductase
BG06_3633	COG1595	DNA-templated transcription, initiation
BG06_3635	COG1191	sigma factor activity
BG06_3638	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BG06_3639	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BG06_364	COG0629	single-stranded DNA binding
BG06_3641	COG1534	Rna-binding protein
BG06_3643	COG1713	HD superfamily hydrolase involved in NAD metabolism
BG06_3644	COG0799	negative regulation of ribosome biogenesis
BG06_3645	COG2226	methyltransferase
BG06_3646	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG06_3647	COG1596	polysaccharide export
BG06_3647	COG1555	photosystem II stabilization
BG06_3648	COG2131	deaminase
BG06_3649	COG2333	competence protein COMEC
BG06_3649	COG0658	competence protein
BG06_3651	COG1466	dna polymerase III delta subunit
BG06_3656	COG1733	regulation of RNA biosynthetic process
BG06_3657	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG06_3659	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BG06_3663	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BG06_3664	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG06_3666	COG1610	YqeY-like protein
BG06_3669	COG1702	phosphate starvation-inducible protein PhoH
BG06_367	COG0488	(ABC) transporter
BG06_3670	COG1480	7TM receptor with intracellular HD hydrolase
BG06_3672	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BG06_3673	COG0295	cytidine deaminase activity
BG06_3674	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BG06_3677	COG0517	IMP dehydrogenase activity
BG06_3679	COG0358	DNA primase activity
BG06_368	COG1418	mRNA catabolic process
BG06_3680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG06_3681	COG2010	Cytochrome c
BG06_3682	COG2384	SAM-dependent methyltransferase
BG06_3683	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BG06_3689	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_3690	COG1121	(ABC) transporter
BG06_3691	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG06_3692	COG0735	belongs to the Fur family
BG06_3697	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BG06_3698	COG0477	Major facilitator Superfamily
BG06_37	COG1476	TRANSCRIPTIONal
BG06_3700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BG06_3701	COG0573	inorganic phosphate transmembrane transporter activity
BG06_3702	COG0581	inorganic phosphate transmembrane transporter activity
BG06_3703	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BG06_3704	COG0704	Plays a role in the regulation of phosphate uptake
BG06_3705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BG06_3707	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BG06_3708	COG4483	Protein conserved in bacteria
BG06_3709	COG1940	carbohydrate kinase activity
BG06_3711	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_3715	COG0626	cystathionine gamma-synthase activity
BG06_3716	COG0626	cystathionine gamma-synthase activity
BG06_3717	COG0646	methionine synthase
BG06_3717	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BG06_3718	COG1410	methionine synthase
BG06_3718	COG0646	methionine synthase
BG06_372	COG2359	stage V sporulation protein S
BG06_3728	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG06_3729	COG1459	type II secretion system
BG06_3731	COG4970	Tfp pilus assembly protein FimT
BG06_3742	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BG06_3748	COG1725	Transcriptional regulator
BG06_3756	COG2076	Multidrug Resistance protein
BG06_3757	COG2076	Multidrug Resistance protein
BG06_3759	COG1609	Transcriptional regulator
BG06_3760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG06_3761	COG0095	Lipoate-protein ligase
BG06_3769	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG06_3770	COG3872	metal-dependent enzyme
BG06_3773	COG0006	proline dipeptidase activity
BG06_3778	COG3854	ATPases associated with a variety of cellular activities
BG06_3787	COG0511	ligase activity, forming carbon-carbon bonds
BG06_3788	COG0439	Biotin carboxylase
BG06_3789	COG1302	Protein conserved in bacteria
BG06_379	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BG06_3794	COG0142	geranyltranstransferase activity
BG06_3796	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BG06_3798	COG0497	DNA recombination
BG06_3799	COG0750	zinc metalloprotease
BG06_38	COG0457	Tetratricopeptide repeat
BG06_380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BG06_3800	COG0745	RESPONSE REGULATOR receiver
BG06_3802	COG3093	addiction module antidote protein HigA
BG06_3803	COG0584	glycerophosphoryl diester phosphodiesterase
BG06_3805	COG3290	protein histidine kinase activity
BG06_3805	COG3829	transcription factor binding
BG06_3806	COG0280	phosphate acetyltransferase
BG06_3807	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG06_3809	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG06_381	COG2146	nitrite reductase [NAD(P)H] activity
BG06_3810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BG06_3811	COG0022	dehydrogenase e1 component
BG06_3812	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG06_3813	COG0772	Belongs to the SEDS family
BG06_3814	COG2816	NAD+ diphosphatase activity
BG06_3817	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG06_3818	COG0765	amino acid transport
BG06_3819	COG1126	abc transporter atp-binding protein
BG06_382	COG1587	Uroporphyrinogen-III synthase
BG06_382	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BG06_3820	COG4129	membrane
BG06_3821	COG1376	ErfK ybiS ycfS ynhG family protein
BG06_3823	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_3824	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG06_3826	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BG06_3829	COG1760	l-serine dehydratase
BG06_3830	COG1760	l-serine dehydratase
BG06_3831	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG06_3832	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_3833	COG0300	oxidoreductase activity
BG06_3838	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG06_384	COG1648	precorrin-2 dehydrogenase activity
BG06_3848	COG1522	sequence-specific DNA binding
BG06_3850	COG0737	Belongs to the 5'-nucleotidase family
BG06_3853	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG06_3856	COG1073	alpha beta
BG06_3856	COG2226	methyltransferase
BG06_3857	COG4106	trans-aconitate 2-methyltransferase activity
BG06_3858	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BG06_386	COG2223	nitrite transmembrane transporter activity
BG06_3862	COG0307	riboflavin synthase, alpha
BG06_3863	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG06_3863	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG06_3866	COG1073	alpha beta
BG06_3867	COG0456	acetyltransferase
BG06_3868	COG1609	Transcriptional regulator
BG06_3869	COG2056	Na+-H+ antiporter family
BG06_3870	COG0596	Alpha beta hydrolase
BG06_3872	COG1525	nuclease
BG06_3872	COG0737	Belongs to the 5'-nucleotidase family
BG06_3872	COG4085	toxin activity
BG06_3874	COG0456	acetyltransferase
BG06_3874	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BG06_3875	COG0656	L-ascorbic acid biosynthetic process
BG06_3876	COG0667	Aldo Keto reductase
BG06_388	COG0314	molybdopterin synthase activity
BG06_3882	COG1300	Membrane
BG06_3883	COG0735	belongs to the Fur family
BG06_3885	COG4974	Belongs to the 'phage' integrase family
BG06_389	COG0303	'Molybdopterin
BG06_3890	COG0598	Magnesium transport protein CorA
BG06_3893	COG1846	Transcriptional regulator
BG06_3897	COG1131	(ABC) transporter
BG06_3898	COG1725	Transcriptional regulator
BG06_3899	COG1686	Belongs to the peptidase S11 family
BG06_39	COG0737	Belongs to the 5'-nucleotidase family
BG06_390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG06_3903	COG0733	neurotransmitter:sodium symporter activity
BG06_3908	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG06_391	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BG06_3911	COG0697	spore germination
BG06_3912	COG0561	phosphatase activity
BG06_3913	COG4086	secreted protein
BG06_3914	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BG06_3915	COG0456	acetyltransferase
BG06_3916	COG1547	Domain of unknown function (DUF309)
BG06_392	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG06_3921	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BG06_3925	COG3711	transcriptional antiterminator
BG06_3926	COG1263	PTS System
BG06_3926	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG06_3926	COG2190	(PTS) system
BG06_393	COG2181	nitrate reductase activity
BG06_3931	COG0778	Nitroreductase
BG06_3932	COG3706	GGDEF domain
BG06_3933	COG2084	Dehydrogenase
BG06_394	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BG06_3940	COG0436	Aminotransferase
BG06_3941	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG06_3945	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_3946	COG1695	Transcriptional regulator
BG06_395	COG1140	nitrate reductase beta subunit
BG06_3953	COG0183	Belongs to the thiolase family
BG06_396	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BG06_3962	COG3842	ATPase activity
BG06_3963	COG0366	Alpha amylase catalytic
BG06_3965	COG2182	Extracellular solute-binding protein
BG06_3966	COG1175	transmembrane transport
BG06_3967	COG3833	ABC-type maltose transport systems, permease component
BG06_3968	COG1609	Transcriptional regulator
BG06_3969	COG0436	Aminotransferase
BG06_397	COG0714	Associated with various cellular activities
BG06_3971	COG2205	protein histidine kinase activity
BG06_3973	COG3209	COG3209 Rhs family protein
BG06_3977	COG2814	Major facilitator Superfamily
BG06_398	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BG06_3984	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BG06_3986	COG1408	metallophosphoesterase
BG06_3987	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_3988	COG2200	EAL domain
BG06_399	COG1305	Transglutaminase-like
BG06_3991	COG4703	Protein of unknown function (DUF1797)
BG06_3993	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BG06_3995	COG0517	IMP dehydrogenase activity
BG06_3996	COG0583	DNA-binding transcription factor activity
BG06_4	COG1686	Belongs to the peptidase S11 family
BG06_400	COG0386	Belongs to the glutathione peroxidase family
BG06_4000	COG0569	domain protein
BG06_4001	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BG06_4003	COG0561	phosphatase activity
BG06_4004	COG0242	peptide deformylase activity
BG06_4006	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BG06_4007	COG0022	dehydrogenase e1 component
BG06_4017	COG1982	Orn Lys Arg decarboxylase major
BG06_402	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BG06_402	COG0426	domain, Protein
BG06_4021	COG0483	inositol monophosphate 1-phosphatase activity
BG06_4026	COG4896	Protein conserved in bacteria
BG06_4028	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BG06_4032	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BG06_4034	COG0772	Belongs to the SEDS family
BG06_4035	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BG06_4042	COG3336	cytochrome c oxidase
BG06_4045	COG2340	Cysteine-rich secretory protein family
BG06_4048	COG0406	alpha-ribazole phosphatase activity
BG06_4049	COG3679	Belongs to the UPF0342 family
BG06_405	COG1595	DNA-templated transcription, initiation
BG06_4052	COG0742	ribosomal rna small subunit methyltransferase
BG06_4053	COG3314	Sporulation integral membrane protein YlbJ
BG06_4055	COG1752	Esterase of the alpha-beta hydrolase superfamily
BG06_4056	COG3480	Lon protease (S16) C-terminal proteolytic domain
BG06_4058	COG1399	metal-binding, possibly nucleic acid-binding protein
BG06_406	COG0604	alcohol dehydrogenase
BG06_4062	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BG06_4065	COG4839	cell division protein FtsL
BG06_4067	COG0768	penicillin binding
BG06_4068	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG06_4071	COG0772	Belongs to the SEDS family
BG06_4074	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BG06_4075	COG0849	cell division
BG06_4076	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BG06_4078	COG1191	sigma factor activity
BG06_4079	COG1191	sigma factor activity
BG06_408	COG0346	lactoylglutathione lyase activity
BG06_4080	COG1873	PFAM PRC-barrel domain
BG06_4082	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BG06_4084	COG0762	integral membrane protein
BG06_4085	COG2302	S4 RNA-binding domain
BG06_4086	COG3599	regulation of cell shape
BG06_409	COG1082	Xylose isomerase domain protein TIM barrel
BG06_4090	COG0564	pseudouridine synthase activity
BG06_4095	COG0505	Belongs to the CarA family
BG06_4103	COG3069	C4-dicarboxylate transmembrane transporter activity
BG06_4107	COG0006	proline dipeptidase activity
BG06_4109	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BG06_4110	COG1561	YicC-like family, N-terminal region
BG06_4112	COG0194	GDP metabolic process
BG06_4114	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG06_4115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BG06_4116	COG0242	peptide deformylase activity
BG06_4118	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BG06_4118	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG06_4120	COG0631	protein serine/threonine phosphatase activity
BG06_4121	COG0515	serine threonine protein kinase
BG06_4121	COG2815	serine threonine protein kinase
BG06_4122	COG1162	GTPase activity
BG06_4123	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BG06_4124	COG1564	THIamine pyrophosphokinase
BG06_4126	COG1302	Protein conserved in bacteria
BG06_4127	COG1461	Dihydroxyacetone kinase
BG06_4128	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BG06_413	COG2226	methyltransferase
BG06_4131	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BG06_4132	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_4135	COG1196	nuclear chromosome segregation
BG06_4136	COG0552	protein localization to endoplasmic reticulum
BG06_4138	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BG06_4140	COG1837	Belongs to the UPF0109 family
BG06_4148	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BG06_4149	COG0758	DNA mediated transformation
BG06_4150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG06_4152	COG4974	Belongs to the 'phage' integrase family
BG06_4158	COG0528	UMP kinase activity
BG06_4161	COG4589	Belongs to the CDS family
BG06_4163	COG0750	zinc metalloprotease
BG06_4167	COG0195	Participates in both transcription termination and antitermination
BG06_4168	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BG06_4169	COG1358	cellular component organization or biogenesis
BG06_4171	COG1550	Protein conserved in bacteria
BG06_4174	COG0196	riboflavin kinase activity
BG06_4177	COG0726	polysaccharide deacetylase
BG06_4178	COG0612	Peptidase, M16
BG06_4179	COG1873	PFAM PRC-barrel domain
BG06_418	COG3874	Sporulation protein YtfJ
BG06_4180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG06_4181	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG06_4182	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG06_4183	COG0527	aspartate kinase activity
BG06_4185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BG06_4186	COG0740	serine-type endopeptidase activity
BG06_4188	COG1674	ftsk spoiiie
BG06_4189	COG2188	Transcriptional regulator
BG06_4194	COG0612	Peptidase, M16
BG06_4195	COG0612	Peptidase, M16
BG06_4196	COG0300	oxidoreductase activity
BG06_4199	COG1426	Protein conserved in bacteria
BG06_42	COG3718	enzyme involved in inositol metabolism
BG06_4200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BG06_4205	COG1692	metallophosphoesterase
BG06_4206	COG2359	stage V sporulation protein S
BG06_4208	COG0674	pyruvate-flavodoxin oxidoreductase activity
BG06_4208	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BG06_4209	COG1013	pyruvate-flavodoxin oxidoreductase activity
BG06_4211	COG4550	Control of competence regulator ComK, YlbF/YmcA
BG06_4215	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BG06_4217	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BG06_4218	COG1368	sulfuric ester hydrolase activity
BG06_4219	COG0562	UDP-galactopyranose mutase
BG06_4220	COG3773	Cell wall hydrolase
BG06_4221	COG1404	Belongs to the peptidase S8 family
BG06_4224	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_4225	COG1380	Effector of murein hydrolase LrgA
BG06_4228	COG3300	MHYT domain
BG06_4228	COG5001	Diguanylate cyclase
BG06_4229	COG0346	lactoylglutathione lyase activity
BG06_4230	COG2267	carboxylic ester hydrolase activity
BG06_4233	COG2364	Membrane
BG06_4235	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BG06_4236	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BG06_4237	COG2169	Transcriptional regulator
BG06_4238	COG0708	Exodeoxyribonuclease III
BG06_4239	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_4240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_4241	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_4242	COG1120	ATPase activity
BG06_4243	COG2819	hydrolase of the alpha beta superfamily
BG06_4245	COG1937	Protein conserved in bacteria
BG06_4246	COG2608	mercury ion transmembrane transporter activity
BG06_4247	COG2217	Heavy metal translocating P-type atpase
BG06_4250	COG2116	formate transmembrane transporter activity
BG06_4251	COG1408	metallophosphoesterase
BG06_4254	COG1113	amino acid transport
BG06_4257	COG2322	membrane
BG06_4258	COG1979	alcohol dehydrogenase
BG06_4259	COG1349	DNA-binding transcription factor activity
BG06_4260	COG1105	Belongs to the carbohydrate kinase PfkB family
BG06_4261	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG06_4261	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG06_4261	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG06_4262	COG1388	LysM domain
BG06_4262	COG3584	3D domain protein
BG06_4268	COG0464	growth
BG06_4270	COG2860	membrane
BG06_4271	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BG06_4272	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BG06_4273	COG0789	Transcriptional regulator
BG06_4274	COG0174	glutamine synthetase
BG06_4275	COG1695	Transcriptional regulator
BG06_4279	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BG06_4281	COG0737	Belongs to the 5'-nucleotidase family
BG06_4290	COG1132	(ABC) transporter
BG06_4291	COG1132	(ABC) transporter
BG06_4296	COG0730	response to heat
BG06_4299	COG1346	cytolysis
BG06_4301	COG0583	DNA-binding transcription factor activity
BG06_4303	COG1131	(ABC) transporter
BG06_4307	COG0785	Cytochrome C biogenesis protein
BG06_4308	COG4846	Membrane protein involved in cytochrome C biogenesis
BG06_4316	COG2226	methyltransferase
BG06_4321	COG0010	Belongs to the arginase family
BG06_4322	COG1329	Transcriptional regulator
BG06_4325	COG1902	pentaerythritol trinitrate reductase activity
BG06_4326	COG0069	glutamate synthase activity
BG06_4327	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG06_4328	COG0346	lactoylglutathione lyase activity
BG06_4329	COG0400	carboxylic ester hydrolase activity
BG06_433	COG4499	WXG100 protein secretion system (Wss), protein YukC
BG06_4330	COG5002	protein histidine kinase activity
BG06_4332	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_4341	COG0318	PFAM AMP-dependent synthetase and ligase
BG06_4342	COG1268	BioY protein
BG06_4343	COG0318	PFAM AMP-dependent synthetase and ligase
BG06_4344	COG0183	Belongs to the thiolase family
BG06_4347	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BG06_4349	COG2211	Major facilitator Superfamily
BG06_4353	COG0726	polysaccharide deacetylase
BG06_4355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BG06_4356	COG2274	protein secretion by the type I secretion system
BG06_4358	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG06_436	COG0842	Transport permease protein
BG06_436	COG1511	domain protein
BG06_4364	COG0824	Thioesterase
BG06_4365	COG4841	protein insertion into membrane
BG06_4369	COG0745	RESPONSE REGULATOR receiver
BG06_4370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG06_4371	COG1832	CoA-binding protein
BG06_4372	COG0187	DNA topoisomerase II activity
BG06_4373	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG06_4374	COG0673	inositol 2-dehydrogenase activity
BG06_4376	COG1131	(ABC) transporter
BG06_4378	COG1595	DNA-templated transcription, initiation
BG06_4380	COG1316	TRANSCRIPTIONal
BG06_4381	COG1301	dicarboxylic acid transport
BG06_4382	COG4166	transmembrane transport
BG06_4383	COG4166	transmembrane transport
BG06_4384	COG2801	Transposase and inactivated derivatives
BG06_4387	COG4166	transmembrane transport
BG06_4388	COG2226	methyltransferase
BG06_4396	COG0697	spore germination
BG06_4397	COG3383	formate dehydrogenase (NAD+) activity
BG06_4398	COG2427	Protein of unknown function (DUF1641)
BG06_4399	COG5609	conserved protein (DUF2294)
BG06_4400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BG06_4402	COG2116	formate transmembrane transporter activity
BG06_4403	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG06_4404	COG0303	'Molybdopterin
BG06_4405	COG0314	molybdopterin synthase activity
BG06_4407	COG0489	protein tyrosine kinase activity
BG06_441	COG0456	acetyltransferase
BG06_4410	COG3326	Membrane
BG06_4411	COG2962	Rard protein
BG06_4412	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BG06_4413	COG1657	PFAM Prenyltransferase squalene oxidase
BG06_4415	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_4416	COG1012	belongs to the aldehyde dehydrogenase family
BG06_4418	COG4145	pantothenate transmembrane transporter activity
BG06_4421	COG0165	Argininosuccinate lyase
BG06_4423	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_4429	COG0716	FMN binding
BG06_4431	COG1278	Cold shock
BG06_4437	COG2720	vancomycin resistance protein
BG06_4438	COG2514	catechol 2,3-dioxygenase activity
BG06_4441	COG1285	pathogenesis
BG06_4443	COG1024	Enoyl-CoA hydratase
BG06_4444	COG1216	Glycosyl transferase, family 2
BG06_4450	COG0277	FAD linked oxidase domain protein
BG06_4451	COG0385	Bile acid
BG06_4453	COG0457	Tetratricopeptide repeat
BG06_4456	COG0604	alcohol dehydrogenase
BG06_4457	COG0640	Transcriptional regulator
BG06_4459	COG0584	glycerophosphoryl diester phosphodiesterase
BG06_4465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BG06_4466	COG1164	Oligoendopeptidase f
BG06_4467	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BG06_4470	COG1193	negative regulation of DNA recombination
BG06_4474	COG0583	DNA-binding transcription factor activity
BG06_448	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_4480	COG0384	phenazine biosynthesis protein PhzF
BG06_4481	COG3739	integral membrane protein
BG06_4482	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_4483	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG06_4484	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_4486	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG06_4487	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BG06_449	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_4493	COG2814	Major facilitator Superfamily
BG06_4494	COG1113	amino acid transport
BG06_4495	COG0604	alcohol dehydrogenase
BG06_450	COG1819	glycosyl
BG06_4502	COG2072	flavoprotein involved in K transport
BG06_4509	COG3757	hydrolase, family 25
BG06_4509	COG3409	Peptidoglycan-binding domain 1 protein
BG06_4510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_4513	COG1151	hydroxylamine reductase activity
BG06_4518	COG3152	Membrane
BG06_4522	COG1309	transcriptional regulator
BG06_4526	COG1191	sigma factor activity
BG06_4528	COG0726	polysaccharide deacetylase
BG06_4530	COG1733	regulation of RNA biosynthetic process
BG06_4531	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG06_4532	COG0318	PFAM AMP-dependent synthetase and ligase
BG06_4534	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_4536	COG0384	phenazine biosynthesis protein PhzF
BG06_454	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG06_4540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_4543	COG1733	regulation of RNA biosynthetic process
BG06_4544	COG1733	regulation of RNA biosynthetic process
BG06_4545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BG06_4546	COG0673	inositol 2-dehydrogenase activity
BG06_4547	COG2188	Transcriptional regulator
BG06_4548	COG1393	Belongs to the ArsC family
BG06_4554	COG0814	amino acid
BG06_4557	COG0656	L-ascorbic acid biosynthetic process
BG06_456	COG0561	phosphatase activity
BG06_4562	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_4564	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG06_4566	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG06_4568	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BG06_4569	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BG06_4571	COG1070	Carbohydrate kinase
BG06_4572	COG2706	6-phosphogluconolactonase activity
BG06_4573	COG3813	Protein conserved in bacteria
BG06_4574	COG1357	PFAM Pentapeptide repeats (8 copies)
BG06_4575	COG0697	spore germination
BG06_4576	COG0789	Transcriptional regulator
BG06_4577	COG1253	flavin adenine dinucleotide binding
BG06_4583	COG0477	Major facilitator Superfamily
BG06_4585	COG2226	methyltransferase
BG06_4589	COG0628	permease
BG06_4591	COG0180	Tryptophanyl-tRNA synthetase
BG06_4593	COG1136	(ABC) transporter
BG06_4595	COG0110	maltose O-acetyltransferase activity
BG06_4596	COG1940	carbohydrate kinase activity
BG06_4597	COG0346	lactoylglutathione lyase activity
BG06_460	COG2211	Major facilitator Superfamily
BG06_4603	COG1011	Hydrolase
BG06_4608	COG1131	(ABC) transporter
BG06_461	COG0154	amidase activity
BG06_4610	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_4614	COG0778	Nitroreductase
BG06_4615	COG1733	regulation of RNA biosynthetic process
BG06_4619	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BG06_462	COG0494	nUDIX hydrolase
BG06_4624	COG3409	Peptidoglycan-binding domain 1 protein
BG06_4624	COG5632	N-Acetylmuramoyl-L-alanine amidase
BG06_4626	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BG06_4629	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BG06_463	COG1876	peptidase activity
BG06_4636	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG06_4638	COG2031	fatty acid transporter
BG06_4641	COG1309	transcriptional regulator
BG06_4642	COG2076	Multidrug Resistance protein
BG06_4646	COG1131	(ABC) transporter
BG06_4647	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BG06_465	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG06_4650	COG2814	Major facilitator Superfamily
BG06_4651	COG1846	Transcriptional regulator
BG06_4653	COG0477	Major facilitator Superfamily
BG06_4662	COG5444	nuclease activity
BG06_4665	COG5444	nuclease activity
BG06_4671	COG5444	nuclease activity
BG06_4672	COG2849	repeat protein
BG06_468	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG06_4681	COG5444	nuclease activity
BG06_469	COG1114	Component of the transport system for branched-chain amino acids
BG06_4705	COG5632	N-Acetylmuramoyl-L-alanine amidase
BG06_4705	COG3409	Peptidoglycan-binding domain 1 protein
BG06_4708	COG2207	Transcriptional regulator
BG06_4708	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG06_4709	COG0662	Cupin 2, conserved barrel domain protein
BG06_4712	COG1595	DNA-templated transcription, initiation
BG06_4716	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG06_472	COG1253	flavin adenine dinucleotide binding
BG06_4720	COG1619	proteins homologs of microcin C7 resistance protein MccF
BG06_4724	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_4726	COG3850	Histidine kinase
BG06_4726	COG5002	protein histidine kinase activity
BG06_4729	COG0577	efflux transmembrane transporter activity
BG06_473	COG2839	Protein conserved in bacteria
BG06_4730	COG1136	(ABC) transporter
BG06_4733	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BG06_4734	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG06_4736	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG06_474	COG0702	epimerase
BG06_4745	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BG06_4753	COG4895	conserved protein (DUF2196)
BG06_4755	COG2814	Major facilitator Superfamily
BG06_4761	COG0346	lactoylglutathione lyase activity
BG06_4765	COG1522	sequence-specific DNA binding
BG06_4766	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_4768	COG3320	Male sterility
BG06_4768	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BG06_4769	COG0456	acetyltransferase
BG06_477	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG06_4771	COG0640	Transcriptional regulator
BG06_4772	COG0346	lactoylglutathione lyase activity
BG06_4773	COG0798	PFAM Bile acid sodium symporter
BG06_478	COG1607	acyl-coa hydrolase
BG06_4780	COG0577	efflux transmembrane transporter activity
BG06_4781	COG1136	(ABC) transporter
BG06_4782	COG4641	Protein conserved in bacteria
BG06_4785	COG2211	Major facilitator Superfamily
BG06_4788	COG1575	Belongs to the MenA family. Type 1 subfamily
BG06_479	COG3689	TIGRFAM TIGR03943 family protein
BG06_4796	COG0714	Associated with various cellular activities
BG06_4799	COG5609	conserved protein (DUF2294)
BG06_48	COG0673	inositol 2-dehydrogenase activity
BG06_480	COG0701	Predicted permease
BG06_4800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BG06_4802	COG0288	reversible hydration of carbon dioxide
BG06_4803	COG0415	Belongs to the DNA photolyase family
BG06_4810	COG0583	DNA-binding transcription factor activity
BG06_4816	COG0598	Magnesium transport protein CorA
BG06_4818	COG0583	DNA-binding transcription factor activity
BG06_482	COG2244	polysaccharide biosynthetic process
BG06_4822	COG1335	isochorismatase
BG06_4823	COG2267	carboxylic ester hydrolase activity
BG06_4824	COG0753	catalase activity
BG06_4825	COG0737	Belongs to the 5'-nucleotidase family
BG06_483	COG0586	Pfam SNARE associated Golgi protein
BG06_4831	COG1115	amino acid carrier protein
BG06_4832	COG2066	Belongs to the glutaminase family
BG06_4833	COG4191	Histidine kinase
BG06_4834	COG0784	Response regulator, receiver
BG06_4835	COG0697	spore germination
BG06_4836	COG0531	amino acid
BG06_484	COG1051	belongs to the nudix hydrolase family
BG06_4840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG06_4841	COG1114	Component of the transport system for branched-chain amino acids
BG06_4842	COG0531	amino acid
BG06_4843	COG0322	excinuclease ABC activity
BG06_4845	COG2207	Transcriptional regulator
BG06_485	COG5337	Spore coat protein CotH
BG06_4850	COG5002	protein histidine kinase activity
BG06_4854	COG1396	sequence-specific DNA binding
BG06_4855	COG0252	asparaginase activity
BG06_4856	COG1027	Aspartate ammonia-lyase
BG06_4858	COG1063	alcohol dehydrogenase
BG06_4864	COG1113	amino acid transport
BG06_4865	COG1280	lysine exporter protein (LysE YggA)
BG06_4866	COG3403	YqcI/YcgG family
BG06_4868	COG5577	PFAM Coat F domain
BG06_487	COG0406	alpha-ribazole phosphatase activity
BG06_4871	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_4873	COG3848	Pyruvate phosphate dikinase
BG06_4873	COG0574	Belongs to the PEP-utilizing enzyme family
BG06_4876	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BG06_4885	COG1960	acyl-CoA dehydrogenase activity
BG06_4887	COG0640	Transcriptional regulator
BG06_4888	COG0860	N-Acetylmuramoyl-L-alanine amidase
BG06_4892	COG1414	Transcriptional regulator
BG06_4893	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BG06_4894	COG1984	allophanate hydrolase subunit 2
BG06_49	COG2814	Major facilitator Superfamily
BG06_490	COG4166	transmembrane transport
BG06_4907	COG4335	DNA alkylation repair
BG06_4909	COG0833	amino acid
BG06_4911	COG0730	response to heat
BG06_4917	COG0596	Alpha beta hydrolase
BG06_4918	COG0745	RESPONSE REGULATOR receiver
BG06_4919	COG0642	Histidine kinase
BG06_492	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BG06_4923	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_4927	COG0456	acetyltransferase
BG06_4928	COG2207	Transcriptional regulator
BG06_4933	COG1136	(ABC) transporter
BG06_4937	COG1725	Transcriptional regulator
BG06_494	COG0702	epimerase
BG06_4944	COG1846	Transcriptional regulator
BG06_4945	COG0778	Nitroreductase
BG06_4957	COG5444	nuclease activity
BG06_4958	COG5444	nuclease activity
BG06_496	COG3443	Belongs to the bacterial solute-binding protein 9 family
BG06_496	COG0803	Belongs to the bacterial solute-binding protein 9 family
BG06_497	COG0456	acetyltransferase
BG06_4970	COG0714	Associated with various cellular activities
BG06_4975	COG1280	lysine exporter protein (LysE YggA)
BG06_4977	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BG06_4979	COG0753	catalase activity
BG06_498	COG0523	cobalamin synthesis protein
BG06_4980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG06_4982	COG0463	Glycosyl transferase, family 2
BG06_4986	COG0463	Glycosyl transferase, family 2
BG06_499	COG4989	oxidoreductase activity
BG06_4991	COG0714	Associated with various cellular activities
BG06_4996	COG0346	lactoylglutathione lyase activity
BG06_5	COG2318	DinB family
BG06_50	COG1609	Transcriptional regulator
BG06_500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_5001	COG3279	Response regulator of the LytR AlgR family
BG06_5003	COG4377	Putative membrane peptidase family (DUF2324)
BG06_5006	COG3655	Transcriptional regulator
BG06_5008	COG1785	Belongs to the alkaline phosphatase family
BG06_5009	COG3239	Fatty acid desaturase
BG06_501	COG1231	oxidoreductase activity
BG06_5010	COG1690	Belongs to the RtcB family
BG06_5011	COG0833	amino acid
BG06_5012	COG1414	Transcriptional regulator
BG06_5013	COG4187	Peptidase family M20/M25/M40
BG06_5014	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG06_5017	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG06_5021	COG2329	Antibiotic biosynthesis monooxygenase
BG06_5028	COG1070	Carbohydrate kinase
BG06_5029	COG2390	Transcriptional regulator
BG06_503	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG06_5031	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG06_5033	COG1879	ABC-type sugar transport system periplasmic component
BG06_5037	COG3829	transcription factor binding
BG06_5037	COG3290	protein histidine kinase activity
BG06_5039	COG1024	Enoyl-CoA hydratase
BG06_5040	COG2610	gluconate transmembrane transporter activity
BG06_5042	COG1388	LysM domain
BG06_5042	COG3584	3D domain protein
BG06_5049	COG1605	Chorismate mutase
BG06_5049	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BG06_5052	COG0287	Prephenate dehydrogenase
BG06_5055	COG1309	transcriptional regulator
BG06_5056	COG1033	growth of symbiont in host cell
BG06_5056	COG2409	Drug exporters of the RND superfamily
BG06_5058	COG0488	(ABC) transporter
BG06_5059	COG1368	sulfuric ester hydrolase activity
BG06_506	COG0783	Belongs to the Dps family
BG06_5060	COG0861	Integral membrane protein TerC family
BG06_5062	COG0726	polysaccharide deacetylase
BG06_5064	COG4912	Dna alkylation repair
BG06_5068	COG2318	DinB family
BG06_5069	COG0697	spore germination
BG06_507	COG3949	Membrane
BG06_5074	COG2746	aminoglycoside 3-N-acetyltransferase activity
BG06_5083	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BG06_5084	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BG06_5085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BG06_5087	COG0628	permease
BG06_5096	COG1131	(ABC) transporter
BG06_5099	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BG06_51	COG0671	phosphoesterase, PA-phosphatase related
BG06_510	COG0840	transmembrane signaling receptor activity
BG06_5101	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BG06_5102	COG0436	Aminotransferase
BG06_5108	COG2226	methyltransferase
BG06_5111	COG2261	transglycosylase associated protein
BG06_5115	COG2814	Major facilitator Superfamily
BG06_5115	COG0477	Major facilitator Superfamily
BG06_5116	COG4533	DNA binding
BG06_5117	COG0789	Transcriptional regulator
BG06_5118	COG1664	Polymer-forming cytoskeletal
BG06_5120	COG2814	Major facilitator Superfamily
BG06_5124	COG1307	EDD domain protein, DegV family
BG06_5126	COG1164	Oligoendopeptidase f
BG06_5133	COG0745	RESPONSE REGULATOR receiver
BG06_5134	COG5002	protein histidine kinase activity
BG06_5144	COG4948	Mandelate Racemase Muconate Lactonizing
BG06_5146	COG4166	transmembrane transport
BG06_5147	COG0519	Catalyzes the synthesis of GMP from XMP
BG06_5148	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BG06_515	COG2814	Major facilitator Superfamily
BG06_5151	COG0586	Pfam SNARE associated Golgi protein
BG06_5159	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG06_516	COG0667	Aldo Keto reductase
BG06_5160	COG3938	Belongs to the proline racemase family
BG06_5162	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG06_5163	COG1012	belongs to the aldehyde dehydrogenase family
BG06_5164	COG1115	amino acid carrier protein
BG06_5165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG06_5168	COG3397	chitin binding
BG06_517	COG0640	Transcriptional regulator
BG06_5173	COG4637	Psort location Cytoplasmic, score
BG06_5177	COG0514	ATP-dependent DNA helicase (RecQ)
BG06_518	COG1404	Belongs to the peptidase S8 family
BG06_5181	COG3973	AAA domain
BG06_519	COG2002	toxin-antitoxin pair type II binding
BG06_5191	COG2333	competence protein COMEC
BG06_5191	COG0658	competence protein
BG06_5193	COG2315	Protein conserved in bacteria
BG06_5195	COG2205	protein histidine kinase activity
BG06_5197	COG3397	chitin binding
BG06_5198	COG2153	protein acetylation
BG06_52	COG2367	Beta-lactamase
BG06_520	COG0577	efflux transmembrane transporter activity
BG06_5202	COG0740	serine-type endopeptidase activity
BG06_5204	COG0517	IMP dehydrogenase activity
BG06_5204	COG4175	Glycine betaine
BG06_5209	COG1051	belongs to the nudix hydrolase family
BG06_5211	COG0572	uridine kinase
BG06_5212	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BG06_5212	COG0456	acetyltransferase
BG06_5213	COG1028	Short-chain dehydrogenase reductase Sdr
BG06_5215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BG06_5216	COG0022	dehydrogenase e1 component
BG06_5217	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG06_5218	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG06_5221	COG1349	DNA-binding transcription factor activity
BG06_5225	COG3284	Transcriptional regulator
BG06_5231	COG1309	transcriptional regulator
BG06_5237	COG3773	Cell wall hydrolase
BG06_5237	COG3409	Peptidoglycan-binding domain 1 protein
BG06_5238	COG2959	enzyme of heme biosynthesis
BG06_5241	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_5249	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_5250	COG0697	spore germination
BG06_5252	COG0201	protein transport
BG06_5256	COG3227	Zinc metalloprotease (Elastase)
BG06_5257	COG1523	belongs to the glycosyl hydrolase 13 family
BG06_5266	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG06_527	COG1752	Esterase of the alpha-beta hydrolase superfamily
BG06_5274	COG0322	excinuclease ABC activity
BG06_5277	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG06_5282	COG4667	esterase of the alpha-beta hydrolase superfamily
BG06_5287	COG3878	Protein conserved in bacteria
BG06_529	COG1279	arginine transmembrane transporter activity
BG06_5294	COG1051	belongs to the nudix hydrolase family
BG06_5295	COG0592	DNA-directed DNA polymerase activity
BG06_5296	COG2816	NAD+ diphosphatase activity
BG06_5299	COG2223	nitrite transmembrane transporter activity
BG06_530	COG2814	Major facilitator Superfamily
BG06_5306	COG0697	spore germination
BG06_5307	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_5310	COG0584	glycerophosphoryl diester phosphodiesterase
BG06_5314	COG2814	Major facilitator Superfamily
BG06_532	COG1082	Xylose isomerase domain protein TIM barrel
BG06_5323	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BG06_5326	COG0671	phosphoesterase, PA-phosphatase related
BG06_5327	COG0604	alcohol dehydrogenase
BG06_5328	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BG06_5330	COG2205	protein histidine kinase activity
BG06_5335	COG1794	racemase activity, acting on amino acids and derivatives
BG06_5336	COG1819	glycosyl
BG06_5338	COG5002	protein histidine kinase activity
BG06_5339	COG0561	phosphatase activity
BG06_5348	COG2124	cytochrome p450
BG06_535	COG0318	PFAM AMP-dependent synthetase and ligase
BG06_5357	COG3728	DNA packaging
BG06_5357	COG5484	DNA packaging
BG06_5358	COG1674	ftsk spoiiie
BG06_5358	COG4980	gas vesicle protein
BG06_536	COG4264	IucA IucC family
BG06_5370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BG06_5372	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_5373	COG0460	homoserine dehydrogenase
BG06_5377	COG0577	efflux transmembrane transporter activity
BG06_5378	COG1136	(ABC) transporter
BG06_538	COG1247	-acetyltransferase
BG06_5382	COG2205	protein histidine kinase activity
BG06_5383	COG0745	RESPONSE REGULATOR receiver
BG06_5385	COG3773	Cell wall hydrolase
BG06_5386	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BG06_5388	COG3386	PFAM SMP-30 Gluconolaconase
BG06_539	COG1285	pathogenesis
BG06_5390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG06_5397	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG06_5405	COG2814	Major facilitator Superfamily
BG06_5407	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BG06_541	COG0726	polysaccharide deacetylase
BG06_5412	COG3227	Zinc metalloprotease (Elastase)
BG06_5416	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BG06_542	COG5002	protein histidine kinase activity
BG06_543	COG0745	RESPONSE REGULATOR receiver
BG06_5431	COG0791	NLP P60 protein
BG06_5431	COG0741	lytic transglycosylase activity
BG06_5446	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG06_5446	COG0551	DNA topoisomerase type I activity
BG06_545	COG1316	TRANSCRIPTIONal
BG06_5454	COG4974	Belongs to the 'phage' integrase family
BG06_5459	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BG06_5464	COG0270	DNA (cytosine-5-)-methyltransferase activity
BG06_5466	COG4166	transmembrane transport
BG06_5475	COG1192	Involved in chromosome partitioning
BG06_5480	COG1309	transcriptional regulator
BG06_5481	COG1683	Conserved Protein
BG06_550	COG0460	homoserine dehydrogenase
BG06_553	COG5658	integral membrane protein
BG06_554	COG0726	polysaccharide deacetylase
BG06_556	COG0300	oxidoreductase activity
BG06_558	COG5002	protein histidine kinase activity
BG06_559	COG0745	RESPONSE REGULATOR receiver
BG06_56	COG1595	DNA-templated transcription, initiation
BG06_560	COG1132	(ABC) transporter
BG06_562	COG1388	LysM domain
BG06_562	COG0791	NLP P60 protein
BG06_564	COG1686	Belongs to the peptidase S11 family
BG06_565	COG1619	proteins homologs of microcin C7 resistance protein MccF
BG06_568	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BG06_569	COG4988	ABC transporter
BG06_570	COG1294	oxidase, subunit
BG06_571	COG1271	oxidase subunit
BG06_577	COG0583	DNA-binding transcription factor activity
BG06_581	COG0411	ABC transporter
BG06_583	COG0523	cobalamin synthesis protein
BG06_584	COG1231	oxidoreductase activity
BG06_585	COG0039	L-malate dehydrogenase activity
BG06_586	COG0628	permease
BG06_589	COG0778	Nitroreductase
BG06_59	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG06_590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BG06_591	COG1959	2 iron, 2 sulfur cluster binding
BG06_592	COG0583	DNA-binding transcription factor activity
BG06_593	COG0697	spore germination
BG06_595	COG4549	nuclear export factor GLE1
BG06_596	COG1276	copper resistance
BG06_596	COG2372	response to copper ion
BG06_598	COG1114	Component of the transport system for branched-chain amino acids
BG06_608	COG2132	Multicopper oxidase
BG06_609	COG0006	proline dipeptidase activity
BG06_614	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BG06_615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG06_617	COG2390	Transcriptional regulator
BG06_624	COG0531	amino acid
BG06_630	COG1914	H( )-stimulated, divalent metal cation uptake system
BG06_634	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG06_639	COG4166	transmembrane transport
BG06_64	COG1846	Transcriptional regulator
BG06_640	COG1073	alpha beta
BG06_644	COG0427	acetyl-CoA hydrolase
BG06_645	COG3279	Response regulator of the LytR AlgR family
BG06_646	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BG06_648	COG3384	dioxygenase
BG06_649	COG2814	Major facilitator Superfamily
BG06_65	COG3961	Belongs to the TPP enzyme family
BG06_654	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BG06_657	COG0440	acetolactate synthase activity
BG06_658	COG0028	Belongs to the TPP enzyme family
BG06_659	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG06_66	COG2226	methyltransferase
BG06_661	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG06_664	COG2323	membrane
BG06_665	COG5566	PFAM Mor transcription activator
BG06_667	COG0733	neurotransmitter:sodium symporter activity
BG06_668	COG2244	polysaccharide biosynthetic process
BG06_671	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG06_672	COG2223	nitrite transmembrane transporter activity
BG06_673	COG4166	transmembrane transport
BG06_674	COG4166	transmembrane transport
BG06_675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BG06_677	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG06_678	COG0477	Major facilitator Superfamily
BG06_68	COG3615	Tellurite resistance protein tehB
BG06_68	COG0500	methyltransferase
BG06_680	COG1695	Transcriptional regulator
BG06_682	COG1966	Carbon starvation protein
BG06_69	COG0577	efflux transmembrane transporter activity
BG06_69	COG1136	(ABC) transporter
BG06_696	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BG06_697	COG0784	Response regulator, receiver
BG06_698	COG4191	Histidine kinase
BG06_699	COG0281	malic enzyme
BG06_7	COG0572	uridine kinase
BG06_700	COG1027	Aspartate ammonia-lyase
BG06_702	COG0528	UMP kinase activity
BG06_707	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG06_710	COG1131	(ABC) transporter
BG06_717	COG2733	membrane
BG06_72	COG1309	transcriptional regulator
BG06_723	COG0785	Cytochrome C biogenesis protein
BG06_727	COG3340	Belongs to the peptidase S51 family
BG06_728	COG0534	Mate efflux family protein
BG06_730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_732	COG0114	fumarate hydratase activity
BG06_734	COG0789	Transcriptional regulator
BG06_735	COG1757	Na H antiporter
BG06_736	COG1216	Glycosyl transferase, family 2
BG06_736	COG0438	transferase activity, transferring glycosyl groups
BG06_738	COG0701	Predicted permease
BG06_739	COG0523	cobalamin synthesis protein
BG06_740	COG0697	spore germination
BG06_741	COG1802	Transcriptional regulator
BG06_750	COG1136	(ABC) transporter
BG06_750	COG0577	efflux transmembrane transporter activity
BG06_755	COG0457	Tetratricopeptide repeat
BG06_759	COG2801	Transposase and inactivated derivatives
BG06_761	COG1923	regulation of RNA biosynthetic process
BG06_766	COG0367	asparagine synthase
BG06_768	COG1846	Transcriptional regulator
BG06_77	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG06_772	COG0406	alpha-ribazole phosphatase activity
BG06_774	COG1686	Belongs to the peptidase S11 family
BG06_779	COG1234	tRNA 3'-trailer cleavage
BG06_780	COG1177	transmembrane transport
BG06_781	COG0725	ABC transporter, periplasmic molybdate-binding protein
BG06_782	COG3842	ATPase activity
BG06_788	COG2329	Antibiotic biosynthesis monooxygenase
BG06_795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BG06_796	COG4786	Flagellar basal body rod
BG06_797	COG1419	protein localization to endoplasmic reticulum
BG06_798	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG06_799	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG06_8	COG1247	-acetyltransferase
BG06_801	COG1987	bacterial-type flagellum assembly
BG06_802	COG1338	Plays a role in the flagellum-specific transport system
BG06_804	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG06_804	COG1776	CheC inhibitor of MCP methylation
BG06_805	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG06_807	COG0741	lytic transglycosylase activity
BG06_808	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG06_809	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG06_811	COG0835	chemotaxis
BG06_811	COG0784	Response regulator, receiver
BG06_818	COG1157	protein secretion by the type III secretion system
BG06_82	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BG06_820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG06_821	COG1766	The M ring may be actively involved in energy transduction
BG06_822	COG1677	Flagellar hook-basal body complex protein FliE
BG06_823	COG1558	bacterial-type flagellum-dependent cell motility
BG06_824	COG1815	bacterial-type flagellum-dependent cell motility
BG06_827	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BG06_828	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG06_829	COG1256	bacterial-type flagellum assembly
BG06_833	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BG06_836	COG1776	CheC inhibitor of MCP methylation
BG06_836	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG06_837	COG0643	Histidine kinase
BG06_837	COG2198	Histidine kinase
BG06_838	COG2201	protein-glutamate methylesterase activity
BG06_839	COG1360	Flagellar Motor Protein
BG06_84	COG2971	BadF BadG BcrA BcrD
BG06_840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BG06_844	COG1923	regulation of RNA biosynthetic process
BG06_857	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BG06_858	COG2323	membrane
BG06_860	COG4978	Transcriptional regulator
BG06_860	COG0789	Transcriptional regulator
BG06_861	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BG06_862	COG0475	glutathione-regulated potassium exporter activity
BG06_864	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG06_865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG06_866	COG3162	membrane
BG06_869	COG1280	lysine exporter protein (LysE YggA)
BG06_870	COG3403	YqcI/YcgG family
BG06_877	COG0328	RNA-DNA hybrid ribonuclease activity
BG06_881	COG0454	-acetyltransferase
BG06_884	COG0438	transferase activity, transferring glycosyl groups
BG06_885	COG1215	transferase activity, transferring glycosyl groups
BG06_888	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG06_89	COG1649	PFAM Uncharacterised BCR, COG1649
BG06_893	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG06_896	COG0754	glutathionylspermidine amidase activity
BG06_902	COG0456	acetyltransferase
BG06_904	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BG06_906	COG2311	Membrane
BG06_907	COG2233	PERMEase
BG06_909	COG0024	Methionine aminopeptidase
BG06_910	COG3173	Aminoglycoside phosphotransferase
BG06_912	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BG06_913	COG1199	ATP-dependent helicase activity
BG06_915	COG0116	Belongs to the methyltransferase superfamily
BG06_926	COG4499	WXG100 protein secretion system (Wss), protein YukC
BG06_926	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG06_928	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BG06_929	COG3935	DnaD domain protein
BG06_933	COG1199	ATP-dependent helicase activity
BG06_933	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BG06_94	COG1595	DNA-templated transcription, initiation
BG06_940	COG0438	transferase activity, transferring glycosyl groups
BG06_941	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BG06_944	COG1694	Mazg nucleotide pyrophosphohydrolase
BG06_945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG06_947	COG2738	Putative neutral zinc metallopeptidase
BG06_950	COG4347	Protein of unknown function (DUF1405)
BG06_952	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BG06_956	COG0457	Tetratricopeptide repeat
BG06_960	COG0105	UTP biosynthetic process
BG06_961	COG0142	geranyltranstransferase activity
BG06_963	COG0142	geranyltranstransferase activity
BG06_966	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BG06_980	COG0252	asparaginase activity
BG06_981	COG0492	ferredoxin-NADP+ reductase activity
BG06_985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG06_986	COG4862	establishment of competence for transformation
BG06_988	COG1408	metallophosphoesterase
BG06_990	COG1266	CAAX protease self-immunity
BG06_991	COG0514	ATP-dependent DNA helicase (RecQ)
BG06_993	COG1141	Ferredoxin
BG06_994	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BG06_996	COG4942	peptidase
BG06_997	COG2096	Adenosyltransferase
BG06_998	COG5002	protein histidine kinase activity
BG06_999	COG0745	RESPONSE REGULATOR receiver