locus-tag	class	description
K8Z20_00005	COG3728	DNA packaging
K8Z20_00005	COG5484	DNA packaging
K8Z20_00095	COG4824	toxin secretion phage lysis holin
K8Z20_00115	COG2252	PERMEase
K8Z20_00125	COG5002	protein histidine kinase activity
K8Z20_00150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z20_00190	COG2205	protein histidine kinase activity
K8Z20_00195	COG0745	RESPONSE REGULATOR receiver
K8Z20_00235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z20_00245	COG1216	Glycosyl transferase, family 2
K8Z20_00245	COG0463	Glycosyl transferase, family 2
K8Z20_00265	COG0697	spore germination
K8Z20_00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z20_00300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z20_00305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z20_00315	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z20_00330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z20_00340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z20_00350	COG0151	Belongs to the GarS family
K8Z20_00375	COG0210	DNA helicase
K8Z20_00385	COG4851	CamS sex pheromone cAM373 precursor
K8Z20_00400	COG1335	isochorismatase
K8Z20_00410	COG2011	ABC-type metal ion transport system permease component
K8Z20_00415	COG1464	Belongs to the NlpA lipoprotein family
K8Z20_00430	COG0003	Pfam Anion-transporting ATPase
K8Z20_00435	COG1846	Transcriptional regulator
K8Z20_00440	COG4682	membrane
K8Z20_00460	COG1597	lipid kinase activity
K8Z20_00470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z20_00480	COG1012	belongs to the aldehyde dehydrogenase family
K8Z20_00485	COG2076	Multidrug Resistance protein
K8Z20_00495	COG2309	aminopeptidase activity
K8Z20_00515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z20_00525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z20_00530	COG4807	Protein conserved in bacteria
K8Z20_00560	COG1473	amidohydrolase
K8Z20_00575	COG0450	alkyl hydroperoxide reductase
K8Z20_00595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_00600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_00605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z20_00610	COG0492	ferredoxin-NADP+ reductase activity
K8Z20_00620	COG0166	Belongs to the GPI family
K8Z20_00645	COG5002	protein histidine kinase activity
K8Z20_00665	COG3541	Predicted nucleotidyltransferase
K8Z20_00670	COG2814	Major facilitator Superfamily
K8Z20_00675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z20_00675	COG0723	plastoquinol--plastocyanin reductase activity
K8Z20_00685	COG0765	amino acid transport
K8Z20_00690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z20_00700	COG0840	transmembrane signaling receptor activity
K8Z20_00725	COG0549	Belongs to the carbamate kinase family
K8Z20_00730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z20_00745	COG0366	Alpha amylase catalytic
K8Z20_00750	COG1263	PTS System
K8Z20_00750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z20_00750	COG2190	(PTS) system
K8Z20_00780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z20_00800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z20_00810	COG1116	anion transmembrane transporter activity
K8Z20_00860	COG2270	Major facilitator Superfamily
K8Z20_00890	COG2310	stress, protein
K8Z20_00895	COG2310	stress, protein
K8Z20_00900	COG2310	stress, protein
K8Z20_00905	COG0861	Integral membrane protein TerC family
K8Z20_00915	COG3853	Toxic anion resistance protein (TelA)
K8Z20_00930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z20_00940	COG1295	ribonuclease BN
K8Z20_00945	COG2217	Heavy metal translocating P-type atpase
K8Z20_00950	COG0697	spore germination
K8Z20_00970	COG0586	Pfam SNARE associated Golgi protein
K8Z20_00985	COG3871	stress protein (general stress protein 26)
K8Z20_00990	COG0387	Pfam Sodium calcium exchanger
K8Z20_01000	COG0535	radical SAM domain protein
K8Z20_01020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z20_01025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z20_01040	COG3829	transcription factor binding
K8Z20_01050	COG0833	amino acid
K8Z20_01055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z20_01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z20_01085	COG1263	PTS System
K8Z20_01090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z20_01105	COG0463	Glycosyl transferase, family 2
K8Z20_01115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z20_01115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z20_01135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z20_01155	COG1228	amidohydrolase
K8Z20_01160	COG1090	epimerase
K8Z20_01190	COG1988	membrane-bound metal-dependent
K8Z20_01195	COG1194	a g-specific adenine glycosylase
K8Z20_01220	COG1132	(ABC) transporter
K8Z20_01225	COG4129	membrane
K8Z20_01230	COG0067	glutamate synthase
K8Z20_01230	COG0069	glutamate synthase activity
K8Z20_01230	COG0070	glutamate synthase
K8Z20_01245	COG4555	ABC transporter
K8Z20_01265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z20_01270	COG0735	belongs to the Fur family
K8Z20_01355	COG4974	Belongs to the 'phage' integrase family
K8Z20_01380	COG0582	viral genome integration into host DNA
K8Z20_01445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z20_01470	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z20_01475	COG1716	ATPase activity
K8Z20_01475	COG5001	Diguanylate cyclase
K8Z20_01480	COG2766	serine protein kinase
K8Z20_01500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z20_01510	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z20_01515	COG2268	Band 7 protein
K8Z20_01525	COG3290	protein histidine kinase activity
K8Z20_01530	COG4565	transcriptional regulatory protein
K8Z20_01535	COG2851	Citrate transporter
K8Z20_01560	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z20_01565	COG3842	ATPase activity
K8Z20_01570	COG1175	transmembrane transport
K8Z20_01575	COG0395	ABC-type sugar transport system, permease component
K8Z20_01585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z20_01590	COG0745	RESPONSE REGULATOR receiver
K8Z20_01595	COG3850	Histidine kinase
K8Z20_01595	COG5002	protein histidine kinase activity
K8Z20_01605	COG4990	cell redox homeostasis
K8Z20_01615	COG3290	protein histidine kinase activity
K8Z20_01620	COG4565	transcriptional regulatory protein
K8Z20_01625	COG3493	citrate carrier protein
K8Z20_01630	COG0281	malic enzyme
K8Z20_01640	COG0697	spore germination
K8Z20_01645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_01655	COG5002	protein histidine kinase activity
K8Z20_01660	COG0745	RESPONSE REGULATOR receiver
K8Z20_01670	COG0454	-acetyltransferase
K8Z20_01670	COG0456	acetyltransferase
K8Z20_01675	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z20_01680	COG3383	formate dehydrogenase (NAD+) activity
K8Z20_01685	COG2427	Protein of unknown function (DUF1641)
K8Z20_01710	COG0640	Transcriptional regulator
K8Z20_01715	COG2217	Heavy metal translocating P-type atpase
K8Z20_01720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z20_01735	COG3227	Zinc metalloprotease (Elastase)
K8Z20_01755	COG2720	vancomycin resistance protein
K8Z20_01760	COG1316	TRANSCRIPTIONal
K8Z20_01765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z20_01770	COG0346	lactoylglutathione lyase activity
K8Z20_01775	COG1253	flavin adenine dinucleotide binding
K8Z20_01780	COG1027	Aspartate ammonia-lyase
K8Z20_01785	COG1620	l-lactate permease
K8Z20_01800	COG3104	oligopeptide transport
K8Z20_01805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z20_01810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_01815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_01825	COG2226	methyltransferase
K8Z20_01835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z20_01845	COG4548	von Willebrand factor, type A
K8Z20_01850	COG0714	Associated with various cellular activities
K8Z20_01870	COG0531	amino acid
K8Z20_01875	COG2188	Transcriptional regulator
K8Z20_01880	COG1263	PTS System
K8Z20_01880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z20_01885	COG0366	Alpha amylase catalytic
K8Z20_01900	COG0697	spore germination
K8Z20_01905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z20_01910	COG1115	amino acid carrier protein
K8Z20_01915	COG1126	abc transporter atp-binding protein
K8Z20_01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z20_01925	COG0765	amino acid transport
K8Z20_01930	COG0765	amino acid transport
K8Z20_01935	COG0833	amino acid
K8Z20_01950	COG1595	DNA-templated transcription, initiation
K8Z20_01960	COG2378	regulation of single-species biofilm formation
K8Z20_01965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z20_01970	COG5002	protein histidine kinase activity
K8Z20_02015	COG1846	Transcriptional regulator
K8Z20_02020	COG0477	Major facilitator Superfamily
K8Z20_02025	COG1609	Transcriptional regulator
K8Z20_02030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z20_02045	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z20_02050	COG1879	ABC-type sugar transport system periplasmic component
K8Z20_02080	COG1063	alcohol dehydrogenase
K8Z20_02135	COG0840	transmembrane signaling receptor activity
K8Z20_02140	COG3584	3D domain protein
K8Z20_02140	COG3583	domain protein
K8Z20_02145	COG1476	TRANSCRIPTIONal
K8Z20_02165	COG3104	oligopeptide transport
K8Z20_02170	COG1114	Component of the transport system for branched-chain amino acids
K8Z20_02185	COG1113	amino acid transport
K8Z20_02190	COG2252	PERMEase
K8Z20_02205	COG2153	protein acetylation
K8Z20_02215	COG0475	glutathione-regulated potassium exporter activity
K8Z20_02215	COG0569	domain protein
K8Z20_02225	COG1845	cytochrome c oxidase, subunit III
K8Z20_02230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z20_02240	COG0833	amino acid
K8Z20_02245	COG4990	cell redox homeostasis
K8Z20_02260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z20_02265	COG0697	spore germination
K8Z20_02270	COG0531	amino acid
K8Z20_02285	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z20_02290	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z20_02295	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z20_02295	COG1918	ferrous iron import across plasma membrane
K8Z20_02300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z20_02305	COG0573	inorganic phosphate transmembrane transporter activity
K8Z20_02310	COG0581	inorganic phosphate transmembrane transporter activity
K8Z20_02315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z20_02435	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z20_02455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z20_02460	COG1116	anion transmembrane transporter activity
K8Z20_02465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z20_02470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z20_02475	COG0352	thiamine-phosphate diphosphorylase activity
K8Z20_02480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z20_02485	COG2104	thiamine diphosphate biosynthetic process
K8Z20_02495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z20_02500	COG0351	phosphomethylpyrimidine kinase
K8Z20_02540	COG2205	protein histidine kinase activity
K8Z20_02545	COG2814	Major facilitator Superfamily
K8Z20_02550	COG1846	Transcriptional regulator
K8Z20_02575	COG1136	(ABC) transporter
K8Z20_02585	COG2252	PERMEase
K8Z20_02590	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_02650	COG0778	Nitroreductase
K8Z20_02655	COG2719	SpoVR family
K8Z20_02665	COG3591	Belongs to the peptidase S1B family
K8Z20_02675	COG0446	pyridine nucleotide-disulphide oxidoreductase
K8Z20_02680	COG1937	Protein conserved in bacteria
K8Z20_02685	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z20_02685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z20_02690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z20_02690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_02695	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z20_02710	COG2210	Belongs to the sulfur carrier protein TusA family
K8Z20_02715	COG0730	response to heat
K8Z20_02725	COG1316	TRANSCRIPTIONal
K8Z20_02730	COG0604	alcohol dehydrogenase
K8Z20_02735	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8Z20_02750	COG3711	transcriptional antiterminator
K8Z20_02750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z20_02755	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z20_02760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z20_02785	COG3584	3D domain protein
K8Z20_02785	COG1388	LysM domain
K8Z20_02790	COG0577	efflux transmembrane transporter activity
K8Z20_02795	COG1136	(ABC) transporter
K8Z20_02805	COG5522	Integral membrane protein (intg_mem_TP0381)
K8Z20_02820	COG1114	Component of the transport system for branched-chain amino acids
K8Z20_02825	COG3546	catalase activity
K8Z20_02860	COG0586	Pfam SNARE associated Golgi protein
K8Z20_02895	COG0531	amino acid
K8Z20_02900	COG0475	glutathione-regulated potassium exporter activity
K8Z20_02910	COG1737	Transcriptional regulator
K8Z20_02920	COG1263	PTS System
K8Z20_02920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z20_02930	COG2259	Doxx family
K8Z20_02950	COG1522	sequence-specific DNA binding
K8Z20_02955	COG0165	Argininosuccinate lyase
K8Z20_02955	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K8Z20_02960	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_02980	COG1309	transcriptional regulator
K8Z20_02985	COG2814	Major facilitator Superfamily
K8Z20_02990	COG1733	regulation of RNA biosynthetic process
K8Z20_03005	COG4533	DNA binding
K8Z20_03010	COG2211	Major facilitator Superfamily
K8Z20_03025	COG0693	protein deglycase activity
K8Z20_03030	COG0753	catalase activity
K8Z20_03040	COG0531	amino acid
K8Z20_03055	COG1012	belongs to the aldehyde dehydrogenase family
K8Z20_03060	COG1132	(ABC) transporter
K8Z20_03065	COG1132	(ABC) transporter
K8Z20_03070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z20_03075	COG0765	amino acid transport
K8Z20_03080	COG1126	abc transporter atp-binding protein
K8Z20_03095	COG0189	ligase activity
K8Z20_03125	COG0028	Belongs to the TPP enzyme family
K8Z20_03130	COG3527	Alpha-acetolactate decarboxylase
K8Z20_03145	COG0561	phosphatase activity
K8Z20_03155	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_03155	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_03160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z20_03165	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_03180	COG0659	secondary active sulfate transmembrane transporter activity
K8Z20_03185	COG2244	polysaccharide biosynthetic process
K8Z20_03205	COG1024	Enoyl-CoA hydratase
K8Z20_03225	COG1363	Peptidase, m42
K8Z20_03265	COG0601	transmembrane transport
K8Z20_03270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z20_03275	COG0444	Belongs to the ABC transporter superfamily
K8Z20_03280	COG4608	Belongs to the ABC transporter superfamily
K8Z20_03285	COG0322	excinuclease ABC activity
K8Z20_03300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_03400	COG0477	Major facilitator Superfamily
K8Z20_03405	COG3290	protein histidine kinase activity
K8Z20_03410	COG4565	transcriptional regulatory protein
K8Z20_03415	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z20_03420	COG0494	nUDIX hydrolase
K8Z20_03435	COG0305	Participates in initiation and elongation during chromosome replication
K8Z20_03455	COG0305	Participates in initiation and elongation during chromosome replication
K8Z20_03480	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K8Z20_03485	COG1288	antiporter activity
K8Z20_03495	COG1842	Phage shock protein A
K8Z20_03505	COG0477	Major facilitator Superfamily
K8Z20_03525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_03575	COG2020	methyltransferase activity
K8Z20_03605	COG1073	alpha beta
K8Z20_03620	COG2801	Transposase and inactivated derivatives
K8Z20_03650	COG0577	efflux transmembrane transporter activity
K8Z20_03665	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z20_03670	COG1522	sequence-specific DNA binding
K8Z20_03685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z20_03740	COG1183	phosphatidylcholine synthase activity
K8Z20_03755	COG2814	Major facilitator Superfamily
K8Z20_03760	COG0640	Transcriptional regulator
K8Z20_03785	COG2376	Dihydroxyacetone kinase
K8Z20_03795	COG2376	Dihydroxyacetone kinase
K8Z20_03825	COG2373	Large extracellular alpha-helical protein
K8Z20_03905	COG1191	sigma factor activity
K8Z20_03915	COG2208	phosphoserine phosphatase activity
K8Z20_03920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z20_03925	COG0784	Response regulator, receiver
K8Z20_03925	COG2205	protein histidine kinase activity
K8Z20_03925	COG5002	protein histidine kinase activity
K8Z20_03965	COG2807	transmembrane transport
K8Z20_03970	COG2186	Transcriptional regulator
K8Z20_03980	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z20_04000	COG0420	3'-5' exonuclease activity
K8Z20_04005	COG4717	serine-type aminopeptidase activity
K8Z20_04015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z20_04030	COG0346	lactoylglutathione lyase activity
K8Z20_04035	COG0346	lactoylglutathione lyase activity
K8Z20_04040	COG0457	Tetratricopeptide repeat
K8Z20_04050	COG2267	carboxylic ester hydrolase activity
K8Z20_04070	COG2140	Oxalate decarboxylase
K8Z20_04075	COG3620	sequence-specific DNA binding
K8Z20_04080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z20_04085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z20_04095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z20_04110	COG1595	DNA-templated transcription, initiation
K8Z20_04120	COG0772	Belongs to the SEDS family
K8Z20_04125	COG3973	AAA domain
K8Z20_04150	COG4980	gas vesicle protein
K8Z20_04155	COG0537	adenosine 5'-monophosphoramidase activity
K8Z20_04160	COG1131	(ABC) transporter
K8Z20_04165	COG4473	ABC transporter
K8Z20_04180	COG1309	transcriptional regulator
K8Z20_04190	COG3402	PFAM membrane-flanked domain
K8Z20_04195	COG3428	Bacterial PH domain
K8Z20_04230	COG0697	spore germination
K8Z20_04235	COG3402	PFAM membrane-flanked domain
K8Z20_04240	COG3428	Bacterial PH domain
K8Z20_04245	COG2329	Antibiotic biosynthesis monooxygenase
K8Z20_04250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z20_04265	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z20_04300	COG1484	DNA-dependent DNA replication
K8Z20_04315	COG1309	transcriptional regulator
K8Z20_04350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_04355	COG1609	Transcriptional regulator
K8Z20_04365	COG1234	tRNA 3'-trailer cleavage
K8Z20_04370	COG0095	Lipoate-protein ligase
K8Z20_04380	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_04390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K8Z20_04400	COG4208	sulfate ABC transporter
K8Z20_04490	COG1073	alpha beta
K8Z20_04495	COG1408	metallophosphoesterase
K8Z20_04500	COG1078	dGTPase activity
K8Z20_04510	COG1595	DNA-templated transcription, initiation
K8Z20_04515	COG2207	Transcriptional regulator
K8Z20_04515	COG3708	Transcriptional regulator
K8Z20_04525	COG2205	protein histidine kinase activity
K8Z20_04530	COG0745	RESPONSE REGULATOR receiver
K8Z20_04550	COG0501	Belongs to the peptidase M48B family
K8Z20_04555	COG0840	transmembrane signaling receptor activity
K8Z20_04560	COG3693	PFAM glycoside hydrolase, family 10
K8Z20_04570	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z20_04575	COG2224	Isocitrate lyase
K8Z20_04590	COG1278	Cold shock
K8Z20_04610	COG0398	Pfam SNARE associated Golgi protein
K8Z20_04670	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z20_04695	COG0367	asparagine synthase
K8Z20_04705	COG0753	catalase activity
K8Z20_04715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z20_04740	COG3339	Conserved Protein
K8Z20_04745	COG0004	ammonium transporteR
K8Z20_04765	COG2996	Protein conserved in bacteria
K8Z20_04790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_04805	COG0561	phosphatase activity
K8Z20_04825	COG2267	carboxylic ester hydrolase activity
K8Z20_04840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z20_04845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z20_04850	COG5504	Zn-dependent protease
K8Z20_04860	COG0180	Tryptophanyl-tRNA synthetase
K8Z20_04870	COG4166	transmembrane transport
K8Z20_04875	COG0601	transmembrane transport
K8Z20_04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z20_04885	COG0444	Belongs to the ABC transporter superfamily
K8Z20_04890	COG4608	Belongs to the ABC transporter superfamily
K8Z20_04895	COG0534	Mate efflux family protein
K8Z20_04900	COG4166	transmembrane transport
K8Z20_04915	COG0861	Integral membrane protein TerC family
K8Z20_04925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z20_04935	COG1164	Oligoendopeptidase f
K8Z20_04950	COG2346	COG2346, Truncated hemoglobins
K8Z20_04955	COG4116	CYTH
K8Z20_04965	COG2357	RelA SpoT domain protein
K8Z20_04975	COG0564	pseudouridine synthase activity
K8Z20_04990	COG0772	Belongs to the SEDS family
K8Z20_04995	COG1216	Glycosyl transferase, family 2
K8Z20_05015	COG0457	Tetratricopeptide repeat
K8Z20_05015	COG0463	Glycosyl transferase, family 2
K8Z20_05035	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z20_05050	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z20_05095	COG2153	protein acetylation
K8Z20_05105	COG2382	esterase
K8Z20_05130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z20_05140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z20_05140	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z20_05175	COG1620	l-lactate permease
K8Z20_05180	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z20_05220	COG2226	methyltransferase
K8Z20_05240	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z20_05250	COG1476	TRANSCRIPTIONal
K8Z20_05295	COG4152	abc transporter atp-binding protein
K8Z20_05300	COG1668	transmembrane transport
K8Z20_05320	COG2226	methyltransferase
K8Z20_05330	COG1686	Belongs to the peptidase S11 family
K8Z20_05335	COG0681	Belongs to the peptidase S26 family
K8Z20_05370	COG1012	belongs to the aldehyde dehydrogenase family
K8Z20_05380	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z20_05385	COG1177	transmembrane transport
K8Z20_05400	COG2409	Drug exporters of the RND superfamily
K8Z20_05410	COG0564	pseudouridine synthase activity
K8Z20_05420	COG2340	Cysteine-rich secretory protein family
K8Z20_05425	COG0247	lactate metabolic process
K8Z20_05430	COG0277	FAD linked oxidase domain protein
K8Z20_05435	COG3835	regulator
K8Z20_05445	COG0745	RESPONSE REGULATOR receiver
K8Z20_05450	COG5002	protein histidine kinase activity
K8Z20_05455	COG2186	Transcriptional regulator
K8Z20_05475	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z20_05485	COG2116	formate transmembrane transporter activity
K8Z20_05490	COG0861	Integral membrane protein TerC family
K8Z20_05495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z20_05505	COG2030	dehydratase
K8Z20_05525	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_05530	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z20_05540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z20_05555	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z20_05560	COG3842	ATPase activity
K8Z20_05585	COG1349	DNA-binding transcription factor activity
K8Z20_05600	COG0235	Class ii aldolase
K8Z20_05610	COG2861	carbohydrate metabolic process
K8Z20_05620	COG3852	Histidine kinase
K8Z20_05625	COG1846	Transcriptional regulator
K8Z20_05635	COG2318	DinB family
K8Z20_05645	COG5002	protein histidine kinase activity
K8Z20_05655	COG0720	synthase
K8Z20_05670	COG4873	Protein conserved in bacteria
K8Z20_05700	COG1780	Probably involved in ribonucleotide reductase function
K8Z20_05705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z20_05715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z20_05720	COG1725	Transcriptional regulator
K8Z20_05725	COG1131	(ABC) transporter
K8Z20_05735	COG1131	(ABC) transporter
K8Z20_05755	COG1522	sequence-specific DNA binding
K8Z20_05765	COG1335	isochorismatase
K8Z20_05775	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z20_05780	COG2070	2-Nitropropane dioxygenase
K8Z20_05785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z20_05795	COG1696	Membrane protein involved in D-alanine export
K8Z20_05820	COG0716	FMN binding
K8Z20_05870	COG1846	Transcriptional regulator
K8Z20_05880	COG1301	dicarboxylic acid transport
K8Z20_05885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z20_05890	COG4709	membrane
K8Z20_05895	COG3874	Sporulation protein YtfJ
K8Z20_05915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z20_05920	COG0028	Belongs to the TPP enzyme family
K8Z20_05925	COG0440	acetolactate synthase activity
K8Z20_06000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z20_06015	COG1183	phosphatidylcholine synthase activity
K8Z20_06020	COG1368	sulfuric ester hydrolase activity
K8Z20_06030	COG0019	diaminopimelate decarboxylase activity
K8Z20_06050	COG0529	Catalyzes the synthesis of activated sulfate
K8Z20_06055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z20_06075	COG1648	precorrin-2 dehydrogenase activity
K8Z20_06080	COG0733	neurotransmitter:sodium symporter activity
K8Z20_06105	COG1757	Na H antiporter
K8Z20_06120	COG4758	membrane
K8Z20_06125	COG4585	Histidine kinase
K8Z20_06130	COG2197	response regulator
K8Z20_06140	COG1114	Component of the transport system for branched-chain amino acids
K8Z20_06190	COG0730	response to heat
K8Z20_06195	COG0306	phosphate transporter
K8Z20_06200	COG1392	Phosphate transport regulator
K8Z20_06205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z20_06220	COG3852	Histidine kinase
K8Z20_06225	COG1801	Protein of unknown function DUF72
K8Z20_06235	COG0582	viral genome integration into host DNA
K8Z20_06240	COG5002	protein histidine kinase activity
K8Z20_06255	COG0392	lysyltransferase activity
K8Z20_06255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z20_06270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z20_06275	COG1686	Belongs to the peptidase S11 family
K8Z20_06280	COG2715	membrane protein required for spore maturation
K8Z20_06285	COG0700	Nucleoside recognition
K8Z20_06290	COG1187	pseudouridine synthase activity
K8Z20_06300	COG1333	cytochrome c biogenesis protein
K8Z20_06305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z20_06310	COG0745	RESPONSE REGULATOR receiver
K8Z20_06315	COG5002	protein histidine kinase activity
K8Z20_06320	COG2096	Adenosyltransferase
K8Z20_06335	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z20_06340	COG1141	Ferredoxin
K8Z20_06350	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z20_06355	COG1266	CAAX protease self-immunity
K8Z20_06365	COG1408	metallophosphoesterase
K8Z20_06370	COG0789	Transcriptional regulator
K8Z20_06380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z20_06400	COG0492	ferredoxin-NADP+ reductase activity
K8Z20_06405	COG0252	asparaginase activity
K8Z20_06475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z20_06490	COG0142	geranyltranstransferase activity
K8Z20_06500	COG0142	geranyltranstransferase activity
K8Z20_06530	COG0457	Tetratricopeptide repeat
K8Z20_06550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z20_06555	COG2010	Cytochrome c
K8Z20_06555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z20_06560	COG4347	Protein of unknown function (DUF1405)
K8Z20_06575	COG2738	Putative neutral zinc metallopeptidase
K8Z20_06585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_06590	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z20_06610	COG0438	transferase activity, transferring glycosyl groups
K8Z20_06645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z20_06645	COG1199	ATP-dependent helicase activity
K8Z20_06665	COG3935	DnaD domain protein
K8Z20_06670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z20_06680	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z20_06680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z20_06735	COG0116	Belongs to the methyltransferase superfamily
K8Z20_06745	COG1199	ATP-dependent helicase activity
K8Z20_06750	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z20_06760	COG0024	Methionine aminopeptidase
K8Z20_06770	COG2233	PERMEase
K8Z20_06775	COG2311	Membrane
K8Z20_06785	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z20_06795	COG0456	acetyltransferase
K8Z20_06825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z20_06840	COG3944	biosynthesis protein
K8Z20_06850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z20_06865	COG1215	transferase activity, transferring glycosyl groups
K8Z20_06870	COG0438	transferase activity, transferring glycosyl groups
K8Z20_06885	COG0454	-acetyltransferase
K8Z20_06905	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z20_06940	COG3403	YqcI/YcgG family
K8Z20_06945	COG1280	lysine exporter protein (LysE YggA)
K8Z20_06965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z20_06970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z20_06980	COG0475	glutathione-regulated potassium exporter activity
K8Z20_06985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z20_06990	COG0789	Transcriptional regulator
K8Z20_06990	COG4978	Transcriptional regulator
K8Z20_07000	COG2323	membrane
K8Z20_07005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z20_07045	COG1923	regulation of RNA biosynthetic process
K8Z20_07055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z20_07060	COG1360	Flagellar Motor Protein
K8Z20_07065	COG2201	protein-glutamate methylesterase activity
K8Z20_07070	COG2198	Histidine kinase
K8Z20_07070	COG0643	Histidine kinase
K8Z20_07075	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z20_07075	COG1776	CheC inhibitor of MCP methylation
K8Z20_07090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z20_07110	COG1256	bacterial-type flagellum assembly
K8Z20_07115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z20_07135	COG1815	bacterial-type flagellum-dependent cell motility
K8Z20_07140	COG1558	bacterial-type flagellum-dependent cell motility
K8Z20_07150	COG1766	The M ring may be actively involved in energy transduction
K8Z20_07155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z20_07165	COG1157	protein secretion by the type III secretion system
K8Z20_07200	COG0835	chemotaxis
K8Z20_07200	COG0784	Response regulator, receiver
K8Z20_07215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z20_07220	COG0741	lytic transglycosylase activity
K8Z20_07230	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z20_07235	COG1776	CheC inhibitor of MCP methylation
K8Z20_07235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z20_07245	COG1338	Plays a role in the flagellum-specific transport system
K8Z20_07250	COG1987	bacterial-type flagellum assembly
K8Z20_07260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z20_07265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z20_07270	COG1419	protein localization to endoplasmic reticulum
K8Z20_07275	COG4786	Flagellar basal body rod
K8Z20_07280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z20_07315	COG2329	Antibiotic biosynthesis monooxygenase
K8Z20_07340	COG0583	DNA-binding transcription factor activity
K8Z20_07345	COG3842	ATPase activity
K8Z20_07385	COG1686	Belongs to the peptidase S11 family
K8Z20_07390	COG0406	alpha-ribazole phosphatase activity
K8Z20_07420	COG0367	asparagine synthase
K8Z20_07450	COG1802	Transcriptional regulator
K8Z20_07455	COG0697	spore germination
K8Z20_07465	COG0523	cobalamin synthesis protein
K8Z20_07470	COG0701	Predicted permease
K8Z20_07485	COG1757	Na H antiporter
K8Z20_07490	COG0789	Transcriptional regulator
K8Z20_07515	COG0534	Mate efflux family protein
K8Z20_07520	COG3340	Belongs to the peptidase S51 family
K8Z20_07545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z20_07565	COG2733	membrane
K8Z20_07600	COG1131	(ABC) transporter
K8Z20_07620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z20_07625	COG0528	UMP kinase activity
K8Z20_07635	COG1027	Aspartate ammonia-lyase
K8Z20_07640	COG0281	malic enzyme
K8Z20_07645	COG4191	Histidine kinase
K8Z20_07650	COG0784	Response regulator, receiver
K8Z20_07655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z20_07670	COG3620	sequence-specific DNA binding
K8Z20_07720	COG1695	Transcriptional regulator
K8Z20_07730	COG0477	Major facilitator Superfamily
K8Z20_07740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z20_07745	COG2223	nitrite transmembrane transporter activity
K8Z20_07750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z20_07770	COG0733	neurotransmitter:sodium symporter activity
K8Z20_07775	COG5566	PFAM Mor transcription activator
K8Z20_07780	COG2323	membrane
K8Z20_07800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z20_07810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z20_07815	COG0028	Belongs to the TPP enzyme family
K8Z20_07835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z20_07860	COG2814	Major facilitator Superfamily
K8Z20_07865	COG3384	dioxygenase
K8Z20_07875	COG3279	Response regulator of the LytR AlgR family
K8Z20_07880	COG0427	acetyl-CoA hydrolase
K8Z20_07900	COG4166	transmembrane transport
K8Z20_07905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_07910	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z20_07925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z20_07930	COG0531	amino acid
K8Z20_07965	COG1309	transcriptional regulator
K8Z20_07970	COG2390	Transcriptional regulator
K8Z20_07980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z20_07985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z20_08000	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z20_08010	COG0006	proline dipeptidase activity
K8Z20_08020	COG2132	Multicopper oxidase
K8Z20_08030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z20_08050	COG1114	Component of the transport system for branched-chain amino acids
K8Z20_08065	COG2372	response to copper ion
K8Z20_08065	COG1276	copper resistance
K8Z20_08070	COG4549	nuclear export factor GLE1
K8Z20_08080	COG0697	spore germination
K8Z20_08085	COG0583	DNA-binding transcription factor activity
K8Z20_08090	COG1959	2 iron, 2 sulfur cluster binding
K8Z20_08095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z20_08100	COG0778	Nitroreductase
K8Z20_08110	COG0628	permease
K8Z20_08120	COG1231	oxidoreductase activity
K8Z20_08125	COG0523	cobalamin synthesis protein
K8Z20_08135	COG0411	ABC transporter
K8Z20_08155	COG0583	DNA-binding transcription factor activity
K8Z20_08195	COG1271	oxidase subunit
K8Z20_08200	COG1294	oxidase, subunit
K8Z20_08205	COG4988	ABC transporter
K8Z20_08210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z20_08220	COG1216	Glycosyl transferase, family 2
K8Z20_08260	COG1686	Belongs to the peptidase S11 family
K8Z20_08275	COG1388	LysM domain
K8Z20_08275	COG0791	NLP P60 protein
K8Z20_08285	COG1132	(ABC) transporter
K8Z20_08290	COG0745	RESPONSE REGULATOR receiver
K8Z20_08295	COG5002	protein histidine kinase activity
K8Z20_08300	COG0300	oxidoreductase activity
K8Z20_08330	COG0460	homoserine dehydrogenase
K8Z20_08355	COG1316	TRANSCRIPTIONal
K8Z20_08370	COG0745	RESPONSE REGULATOR receiver
K8Z20_08375	COG5002	protein histidine kinase activity
K8Z20_08390	COG1285	pathogenesis
K8Z20_08395	COG1247	-acetyltransferase
K8Z20_08420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z20_08430	COG1082	Xylose isomerase domain protein TIM barrel
K8Z20_08440	COG2814	Major facilitator Superfamily
K8Z20_08445	COG1279	arginine transmembrane transporter activity
K8Z20_08450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_08460	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z20_08495	COG0577	efflux transmembrane transporter activity
K8Z20_08500	COG2002	toxin-antitoxin pair type II binding
K8Z20_08505	COG1404	Belongs to the peptidase S8 family
K8Z20_08510	COG0640	Transcriptional regulator
K8Z20_08515	COG0667	Aldo Keto reductase
K8Z20_08520	COG2814	Major facilitator Superfamily
K8Z20_08525	COG3152	Membrane
K8Z20_08550	COG0840	transmembrane signaling receptor activity
K8Z20_08565	COG3949	Membrane
K8Z20_08570	COG0783	Belongs to the Dps family
K8Z20_08585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z20_08595	COG1231	oxidoreductase activity
K8Z20_08600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_08605	COG4989	oxidoreductase activity
K8Z20_08615	COG0523	cobalamin synthesis protein
K8Z20_08620	COG0456	acetyltransferase
K8Z20_08625	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z20_08635	COG0702	epimerase
K8Z20_08645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z20_08655	COG4166	transmembrane transport
K8Z20_08680	COG5337	Spore coat protein CotH
K8Z20_08685	COG1051	belongs to the nudix hydrolase family
K8Z20_08690	COG0586	Pfam SNARE associated Golgi protein
K8Z20_08705	COG0701	Predicted permease
K8Z20_08710	COG3689	TIGRFAM TIGR03943 family protein
K8Z20_08715	COG1607	acyl-coa hydrolase
K8Z20_08725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z20_08740	COG0702	epimerase
K8Z20_08745	COG2839	Protein conserved in bacteria
K8Z20_08750	COG1253	flavin adenine dinucleotide binding
K8Z20_08770	COG1114	Component of the transport system for branched-chain amino acids
K8Z20_08775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z20_08795	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z20_08805	COG1876	peptidase activity
K8Z20_08820	COG2211	Major facilitator Superfamily
K8Z20_08835	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z20_08845	COG0561	phosphatase activity
K8Z20_08860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z20_08875	COG1819	glycosyl
K8Z20_08880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_08885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_08915	COG0456	acetyltransferase
K8Z20_08950	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z20_09015	COG3874	Sporulation protein YtfJ
K8Z20_09040	COG2226	methyltransferase
K8Z20_09065	COG1082	Xylose isomerase domain protein TIM barrel
K8Z20_09070	COG0346	lactoylglutathione lyase activity
K8Z20_09085	COG1595	DNA-templated transcription, initiation
K8Z20_09100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z20_09100	COG0426	domain, Protein
K8Z20_09110	COG0386	Belongs to the glutathione peroxidase family
K8Z20_09120	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z20_09125	COG0714	Associated with various cellular activities
K8Z20_09130	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z20_09135	COG1140	nitrate reductase beta subunit
K8Z20_09140	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z20_09145	COG2181	nitrate reductase activity
K8Z20_09150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z20_09155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z20_09160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z20_09165	COG0303	'Molybdopterin
K8Z20_09170	COG0314	molybdopterin synthase activity
K8Z20_09175	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K8Z20_09180	COG2223	nitrite transmembrane transporter activity
K8Z20_09190	COG1648	precorrin-2 dehydrogenase activity
K8Z20_09200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z20_09200	COG1587	Uroporphyrinogen-III synthase
K8Z20_09205	COG2146	nitrite reductase [NAD(P)H] activity
K8Z20_09210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z20_09215	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z20_09250	COG2359	stage V sporulation protein S
K8Z20_09275	COG0730	response to heat
K8Z20_09300	COG0457	Tetratricopeptide repeat
K8Z20_09315	COG1418	mRNA catabolic process
K8Z20_09320	COG0488	(ABC) transporter
K8Z20_09365	COG1476	TRANSCRIPTIONal
K8Z20_09385	COG0629	single-stranded DNA binding
K8Z20_09395	COG1413	lyase activity
K8Z20_09410	COG2136	Putative SAM-dependent methyltransferase
K8Z20_09410	COG2521	methyltransferase
K8Z20_09415	COG0018	arginyl-trna synthetase
K8Z20_09470	COG0017	Asparaginyl-tRNA synthetase
K8Z20_09500	COG2610	gluconate transmembrane transporter activity
K8Z20_09510	COG1794	racemase activity, acting on amino acids and derivatives
K8Z20_09520	COG0456	acetyltransferase
K8Z20_09530	COG3655	Transcriptional regulator
K8Z20_09535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z20_09545	COG1131	(ABC) transporter
K8Z20_09550	COG4473	ABC transporter
K8Z20_09560	COG0546	phosphoglycolate phosphatase activity
K8Z20_09575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z20_09590	COG0768	penicillin binding
K8Z20_09600	COG0204	Acyl-transferase
K8Z20_09610	COG1272	protein, Hemolysin III
K8Z20_09620	COG0805	protein transport
K8Z20_09630	COG1307	EDD domain protein, DegV family
K8Z20_09640	COG1999	signal sequence binding
K8Z20_09645	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z20_09650	COG0367	asparagine synthase
K8Z20_09665	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z20_09670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z20_09675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z20_09695	COG1335	isochorismatase
K8Z20_09710	COG0668	transmembrane transport
K8Z20_09715	COG4585	Histidine kinase
K8Z20_09715	COG2203	Gaf domain
K8Z20_09720	COG2197	response regulator
K8Z20_09725	COG1737	Transcriptional regulator
K8Z20_09730	COG0384	phenazine biosynthesis protein PhzF
K8Z20_09735	COG1064	alcohol dehydrogenase
K8Z20_09760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z20_09795	COG0517	IMP dehydrogenase activity
K8Z20_09795	COG1125	glycine betaine transport
K8Z20_09800	COG1174	glycine betaine transport
K8Z20_09835	COG1253	flavin adenine dinucleotide binding
K8Z20_09840	COG1012	belongs to the aldehyde dehydrogenase family
K8Z20_09845	COG5506	Protein of unknown function (DUF1694)
K8Z20_09860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z20_09865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z20_09870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z20_09875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z20_09880	COG0456	acetyltransferase
K8Z20_09885	COG3829	transcription factor binding
K8Z20_09890	COG1509	lysine 2,3-aminomutase activity
K8Z20_09925	COG0515	serine threonine protein kinase
K8Z20_09925	COG3064	Membrane
K8Z20_09925	COG4991	sh3 domain protein
K8Z20_09935	COG0671	phosphoesterase, PA-phosphatase related
K8Z20_09940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z20_09945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z20_10025	COG0300	oxidoreductase activity
K8Z20_10045	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z20_10045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z20_10055	COG2814	Major facilitator Superfamily
K8Z20_10060	COG4841	protein insertion into membrane
K8Z20_10065	COG0372	Belongs to the citrate synthase family
K8Z20_10070	COG2079	MmgE PrpD family protein
K8Z20_10075	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z20_10080	COG1960	acyl-CoA dehydrogenase activity
K8Z20_10085	COG2084	Dehydrogenase
K8Z20_10095	COG1280	lysine exporter protein (LysE YggA)
K8Z20_10100	COG1024	Enoyl-CoA hydratase
K8Z20_10115	COG0420	3'-5' exonuclease activity
K8Z20_10120	COG0419	ATPase involved in DNA repair
K8Z20_10140	COG2223	nitrite transmembrane transporter activity
K8Z20_10145	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_10150	COG1169	isochorismate synthase
K8Z20_10155	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z20_10160	COG1535	isochorismatase
K8Z20_10160	COG3433	isochorismatase activity
K8Z20_10165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z20_10170	COG3251	PFAM MbtH domain protein
K8Z20_10175	COG2814	Major facilitator Superfamily
K8Z20_10190	COG0776	regulation of translation
K8Z20_10200	COG2318	DinB family
K8Z20_10210	COG1115	amino acid carrier protein
K8Z20_10225	COG2329	Antibiotic biosynthesis monooxygenase
K8Z20_10230	COG1187	pseudouridine synthase activity
K8Z20_10235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z20_10240	COG1136	(ABC) transporter
K8Z20_10255	COG0028	Belongs to the TPP enzyme family
K8Z20_10295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z20_10320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_10355	COG1247	-acetyltransferase
K8Z20_10380	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z20_10390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_10425	COG0583	DNA-binding transcription factor activity
K8Z20_10430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z20_10450	COG0583	DNA-binding transcription factor activity
K8Z20_10455	COG2258	MOSC domain
K8Z20_10470	COG1132	(ABC) transporter
K8Z20_10475	COG1132	(ABC) transporter
K8Z20_10500	COG1396	sequence-specific DNA binding
K8Z20_10570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z20_10575	COG1595	DNA-templated transcription, initiation
K8Z20_10600	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z20_10625	COG2971	BadF BadG BcrA BcrD
K8Z20_10645	COG1846	Transcriptional regulator
K8Z20_10665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_10685	COG1309	transcriptional regulator
K8Z20_10710	COG0500	methyltransferase
K8Z20_10710	COG3615	Tellurite resistance protein tehB
K8Z20_10720	COG2226	methyltransferase
K8Z20_10725	COG3961	Belongs to the TPP enzyme family
K8Z20_10730	COG1846	Transcriptional regulator
K8Z20_10760	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z20_10785	COG2002	toxin-antitoxin pair type II binding
K8Z20_10795	COG0730	response to heat
K8Z20_10800	COG0110	maltose O-acetyltransferase activity
K8Z20_10805	COG1686	Belongs to the peptidase S11 family
K8Z20_10820	COG2814	Major facilitator Superfamily
K8Z20_10885	COG0741	lytic transglycosylase activity
K8Z20_10890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_10895	COG2239	Acts as a magnesium transporter
K8Z20_11005	COG1396	sequence-specific DNA binding
K8Z20_11025	COG1309	transcriptional regulator
K8Z20_11030	COG0367	asparagine synthase
K8Z20_11055	COG1760	l-serine dehydratase
K8Z20_11060	COG1760	l-serine dehydratase
K8Z20_11065	COG0814	amino acid
K8Z20_11085	COG1533	DNA photolyase activity
K8Z20_11095	COG0076	glutamate decarboxylase activity
K8Z20_11105	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z20_11140	COG0772	Belongs to the SEDS family
K8Z20_11145	COG2239	Acts as a magnesium transporter
K8Z20_11155	COG0768	penicillin binding
K8Z20_11160	COG1595	DNA-templated transcription, initiation
K8Z20_11170	COG0768	penicillin binding
K8Z20_11175	COG0768	penicillin binding
K8Z20_11190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_11205	COG1131	(ABC) transporter
K8Z20_11215	COG0582	viral genome integration into host DNA
K8Z20_11225	COG3620	sequence-specific DNA binding
K8Z20_11255	COG1484	DNA-dependent DNA replication
K8Z20_11270	COG2002	toxin-antitoxin pair type II binding
K8Z20_11460	COG4824	toxin secretion phage lysis holin
K8Z20_11500	COG1309	transcriptional regulator
K8Z20_11515	COG1960	acyl-CoA dehydrogenase activity
K8Z20_11520	COG0439	Biotin carboxylase
K8Z20_11525	COG0511	ligase activity, forming carbon-carbon bonds
K8Z20_11530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z20_11535	COG1024	Enoyl-CoA hydratase
K8Z20_11540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z20_11545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z20_11575	COG0572	uridine kinase
K8Z20_11595	COG1686	Belongs to the peptidase S11 family
K8Z20_11620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z20_11635	COG3227	Zinc metalloprotease (Elastase)
K8Z20_11640	COG2207	Transcriptional regulator
K8Z20_11685	COG1942	4-Oxalocrotonate Tautomerase
K8Z20_11690	COG0583	DNA-binding transcription factor activity
K8Z20_11700	COG1131	(ABC) transporter
K8Z20_11730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_11735	COG2368	4-hydroxyphenylacetate
K8Z20_11760	COG2323	membrane
K8Z20_11765	COG0693	protein deglycase activity
K8Z20_11775	COG3386	PFAM SMP-30 Gluconolaconase
K8Z20_11785	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z20_11790	COG3773	Cell wall hydrolase
K8Z20_11800	COG0745	RESPONSE REGULATOR receiver
K8Z20_11805	COG2205	protein histidine kinase activity
K8Z20_11810	COG0488	(ABC) transporter
K8Z20_11820	COG1136	(ABC) transporter
K8Z20_11825	COG0577	efflux transmembrane transporter activity
K8Z20_11845	COG0460	homoserine dehydrogenase
K8Z20_11850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_11860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z20_11930	COG2124	cytochrome p450
K8Z20_11965	COG0561	phosphatase activity
K8Z20_11970	COG5002	protein histidine kinase activity
K8Z20_11975	COG0768	penicillin binding
K8Z20_11985	COG1819	glycosyl
K8Z20_11990	COG1794	racemase activity, acting on amino acids and derivatives
K8Z20_12015	COG2205	protein histidine kinase activity
K8Z20_12020	COG0582	viral genome integration into host DNA
K8Z20_12065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z20_12080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z20_12090	COG0745	RESPONSE REGULATOR receiver
K8Z20_12095	COG5002	protein histidine kinase activity
K8Z20_12100	COG0604	alcohol dehydrogenase
K8Z20_12105	COG0671	phosphoesterase, PA-phosphatase related
K8Z20_12110	COG0768	penicillin binding
K8Z20_12165	COG2814	Major facilitator Superfamily
K8Z20_12170	COG2814	Major facilitator Superfamily
K8Z20_12185	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z20_12200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_12205	COG0697	spore germination
K8Z20_12240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z20_12250	COG2223	nitrite transmembrane transporter activity
K8Z20_12265	COG0592	DNA-directed DNA polymerase activity
K8Z20_12300	COG3878	Protein conserved in bacteria
K8Z20_12320	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z20_12360	COG0322	excinuclease ABC activity
K8Z20_12380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z20_12410	COG1011	Hydrolase
K8Z20_12415	COG0745	RESPONSE REGULATOR receiver
K8Z20_12420	COG5002	protein histidine kinase activity
K8Z20_12435	COG1136	(ABC) transporter
K8Z20_12440	COG0577	efflux transmembrane transporter activity
K8Z20_12445	COG1073	alpha beta
K8Z20_12450	COG0657	acetylesterase activity
K8Z20_12455	COG0076	glutamate decarboxylase activity
K8Z20_12470	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z20_12475	COG3227	Zinc metalloprotease (Elastase)
K8Z20_12480	COG0737	Belongs to the 5'-nucleotidase family
K8Z20_12495	COG0201	protein transport
K8Z20_12500	COG0697	spore germination
K8Z20_12505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_12540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_12555	COG2959	enzyme of heme biosynthesis
K8Z20_12595	COG1309	transcriptional regulator
K8Z20_12625	COG3284	Transcriptional regulator
K8Z20_12660	COG1959	2 iron, 2 sulfur cluster binding
K8Z20_12675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z20_12680	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z20_12685	COG0022	dehydrogenase e1 component
K8Z20_12690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z20_12700	COG2814	Major facilitator Superfamily
K8Z20_12710	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_12715	COG0456	acetyltransferase
K8Z20_12715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z20_12755	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z20_12760	COG0517	IMP dehydrogenase activity
K8Z20_12760	COG4175	Glycine betaine
K8Z20_12790	COG2153	protein acetylation
K8Z20_12795	COG3397	chitin binding
K8Z20_12800	COG1819	glycosyl
K8Z20_12820	COG2205	protein histidine kinase activity
K8Z20_12825	COG2226	methyltransferase
K8Z20_12830	COG2315	Protein conserved in bacteria
K8Z20_12875	COG0456	acetyltransferase
K8Z20_12880	COG3973	AAA domain
K8Z20_12890	COG2105	PFAM AIG2 family protein
K8Z20_12895	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z20_12930	COG4637	Psort location Cytoplasmic, score
K8Z20_12945	COG3397	chitin binding
K8Z20_12960	COG1162	GTPase activity
K8Z20_12965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z20_12970	COG1115	amino acid carrier protein
K8Z20_12975	COG1012	belongs to the aldehyde dehydrogenase family
K8Z20_12980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z20_12990	COG3938	Belongs to the proline racemase family
K8Z20_12995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z20_13035	COG0586	Pfam SNARE associated Golgi protein
K8Z20_13045	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z20_13055	COG4166	transmembrane transport
K8Z20_13065	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z20_13080	COG0667	Aldo Keto reductase
K8Z20_13125	COG3850	Histidine kinase
K8Z20_13125	COG5002	protein histidine kinase activity
K8Z20_13130	COG0745	RESPONSE REGULATOR receiver
K8Z20_13150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z20_13160	COG1164	Oligoendopeptidase f
K8Z20_13165	COG1307	EDD domain protein, DegV family
K8Z20_13210	COG2814	Major facilitator Superfamily
K8Z20_13220	COG1664	Polymer-forming cytoskeletal
K8Z20_13225	COG0789	Transcriptional regulator
K8Z20_13230	COG4533	DNA binding
K8Z20_13235	COG0477	Major facilitator Superfamily
K8Z20_13235	COG2814	Major facilitator Superfamily
K8Z20_13260	COG2261	transglycosylase associated protein
K8Z20_13275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K8Z20_13310	COG0436	Aminotransferase
K8Z20_13315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z20_13325	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8Z20_13340	COG1131	(ABC) transporter
K8Z20_13390	COG0628	permease
K8Z20_13405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z20_13410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z20_13415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z20_13445	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z20_13465	COG0697	spore germination
K8Z20_13490	COG4912	Dna alkylation repair
K8Z20_13495	COG0346	lactoylglutathione lyase activity
K8Z20_13500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_13510	COG0861	Integral membrane protein TerC family
K8Z20_13520	COG1368	sulfuric ester hydrolase activity
K8Z20_13525	COG0488	(ABC) transporter
K8Z20_13540	COG1033	growth of symbiont in host cell
K8Z20_13540	COG2409	Drug exporters of the RND superfamily
K8Z20_13545	COG1309	transcriptional regulator
K8Z20_13560	COG0287	Prephenate dehydrogenase
K8Z20_13575	COG1605	Chorismate mutase
K8Z20_13575	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z20_13620	COG1388	LysM domain
K8Z20_13620	COG3584	3D domain protein
K8Z20_13635	COG0277	FAD linked oxidase domain protein
K8Z20_13650	COG1879	ABC-type sugar transport system periplasmic component
K8Z20_13660	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z20_13670	COG2390	Transcriptional regulator
K8Z20_13675	COG1070	Carbohydrate kinase
K8Z20_13700	COG2329	Antibiotic biosynthesis monooxygenase
K8Z20_13720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z20_13740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z20_13745	COG4187	Peptidase family M20/M25/M40
K8Z20_13750	COG1414	Transcriptional regulator
K8Z20_13755	COG0833	amino acid
K8Z20_13765	COG3239	Fatty acid desaturase
K8Z20_13775	COG2720	vancomycin resistance protein
K8Z20_13780	COG1785	Belongs to the alkaline phosphatase family
K8Z20_13790	COG3655	Transcriptional regulator
K8Z20_13810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_13815	COG0346	lactoylglutathione lyase activity
K8Z20_13835	COG0714	Associated with various cellular activities
K8Z20_13880	COG0463	Glycosyl transferase, family 2
K8Z20_13900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z20_13905	COG0753	catalase activity
K8Z20_13945	COG0714	Associated with various cellular activities
K8Z20_14030	COG0778	Nitroreductase
K8Z20_14035	COG1846	Transcriptional regulator
K8Z20_14055	COG4884	unkown
K8Z20_14055	COG3831	ATPase activity
K8Z20_14080	COG0037	tRNA processing
K8Z20_14080	COG0590	tRNA wobble adenosine to inosine editing
K8Z20_14090	COG0456	acetyltransferase
K8Z20_14105	COG0697	spore germination
K8Z20_14110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_14150	COG0730	response to heat
K8Z20_14160	COG0833	amino acid
K8Z20_14205	COG0768	penicillin binding
K8Z20_14240	COG1984	allophanate hydrolase subunit 2
K8Z20_14245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z20_14250	COG1414	Transcriptional regulator
K8Z20_14260	COG3142	Participates in the control of copper homeostasis
K8Z20_14265	COG0640	Transcriptional regulator
K8Z20_14275	COG1960	acyl-CoA dehydrogenase activity
K8Z20_14290	COG3314	Sporulation integral membrane protein YlbJ
K8Z20_14300	COG0454	-acetyltransferase
K8Z20_14310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z20_14335	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z20_14335	COG3848	Pyruvate phosphate dikinase
K8Z20_14355	COG1522	sequence-specific DNA binding
K8Z20_14360	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_14365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_14385	COG1063	alcohol dehydrogenase
K8Z20_14390	COG5002	protein histidine kinase activity
K8Z20_14415	COG2207	Transcriptional regulator
K8Z20_14435	COG0737	Belongs to the 5'-nucleotidase family
K8Z20_14440	COG2267	carboxylic ester hydrolase activity
K8Z20_14445	COG1335	isochorismatase
K8Z20_14470	COG2801	Transposase and inactivated derivatives
K8Z20_14480	COG0583	DNA-binding transcription factor activity
K8Z20_14490	COG2814	Major facilitator Superfamily
K8Z20_14525	COG0598	Magnesium transport protein CorA
K8Z20_14595	COG0657	acetylesterase activity
K8Z20_14600	COG0288	reversible hydration of carbon dioxide
K8Z20_14610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z20_14615	COG5609	conserved protein (DUF2294)
K8Z20_14625	COG0456	acetyltransferase
K8Z20_14630	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z20_14640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_14650	COG0798	PFAM Bile acid sodium symporter
K8Z20_14655	COG0346	lactoylglutathione lyase activity
K8Z20_14660	COG0640	Transcriptional regulator
K8Z20_14665	COG2814	Major facilitator Superfamily
K8Z20_14670	COG1309	transcriptional regulator
K8Z20_14675	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_14680	COG1522	sequence-specific DNA binding
K8Z20_14700	COG0346	lactoylglutathione lyase activity
K8Z20_14795	COG2814	Major facilitator Superfamily
K8Z20_14810	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z20_14820	COG1690	Belongs to the RtcB family
K8Z20_14830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z20_14850	COG0577	efflux transmembrane transporter activity
K8Z20_14855	COG5002	protein histidine kinase activity
K8Z20_14855	COG3850	Histidine kinase
K8Z20_14865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_14895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z20_14925	COG3831	ATPase activity
K8Z20_14940	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_14940	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_15020	COG5444	nuclease activity
K8Z20_15045	COG1876	peptidase activity
K8Z20_15050	COG2843	Capsule synthesis protein
K8Z20_15060	COG0477	Major facilitator Superfamily
K8Z20_15075	COG1846	Transcriptional regulator
K8Z20_15080	COG2814	Major facilitator Superfamily
K8Z20_15095	COG2031	fatty acid transporter
K8Z20_15105	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z20_15160	COG1288	antiporter activity
K8Z20_15180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z20_15190	COG1733	regulation of RNA biosynthetic process
K8Z20_15195	COG0778	Nitroreductase
K8Z20_15205	COG0469	pyruvate kinase activity
K8Z20_15225	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_15235	COG1131	(ABC) transporter
K8Z20_15260	COG1011	Hydrolase
K8Z20_15270	COG2365	Tyrosine phosphatase family
K8Z20_15305	COG0628	permease
K8Z20_15330	COG0500	methyltransferase
K8Z20_15340	COG0477	Major facilitator Superfamily
K8Z20_15370	COG1253	flavin adenine dinucleotide binding
K8Z20_15375	COG0789	Transcriptional regulator
K8Z20_15385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z20_15415	COG0697	spore germination
K8Z20_15425	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z20_15430	COG3813	Protein conserved in bacteria
K8Z20_15435	COG2706	6-phosphogluconolactonase activity
K8Z20_15440	COG1070	Carbohydrate kinase
K8Z20_15450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z20_15455	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z20_15460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z20_15465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z20_15490	COG0840	transmembrane signaling receptor activity
K8Z20_15500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z20_15500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z20_15505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z20_15505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z20_15510	COG1733	regulation of RNA biosynthetic process
K8Z20_15525	COG0814	amino acid
K8Z20_15555	COG2188	Transcriptional regulator
K8Z20_15560	COG0673	inositol 2-dehydrogenase activity
K8Z20_15580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_15600	COG0384	phenazine biosynthesis protein PhzF
K8Z20_15620	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_15625	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z20_15630	COG1733	regulation of RNA biosynthetic process
K8Z20_15655	COG1191	sigma factor activity
K8Z20_15710	COG1151	hydroxylamine reductase activity
K8Z20_15775	COG1113	amino acid transport
K8Z20_15780	COG2814	Major facilitator Superfamily
K8Z20_15815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z20_15820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z20_15830	COG1247	-acetyltransferase
K8Z20_15835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z20_15840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_15845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_15850	COG3739	integral membrane protein
K8Z20_15875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_15890	COG0583	DNA-binding transcription factor activity
K8Z20_15900	COG2890	protein-(glutamine-N5) methyltransferase activity
K8Z20_15915	COG1193	negative regulation of DNA recombination
K8Z20_15925	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z20_15930	COG1164	Oligoendopeptidase f
K8Z20_15960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z20_15990	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z20_16000	COG0640	Transcriptional regulator
K8Z20_16005	COG0604	alcohol dehydrogenase
K8Z20_16015	COG0457	Tetratricopeptide repeat
K8Z20_16025	COG0385	Bile acid
K8Z20_16030	COG0277	FAD linked oxidase domain protein
K8Z20_16055	COG1183	phosphatidylcholine synthase activity
K8Z20_16060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z20_16060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_16065	COG1252	NADH dehydrogenase
K8Z20_16075	COG0823	Involved in the tonB-independent uptake of proteins
K8Z20_16080	COG3397	chitin binding
K8Z20_16090	COG0697	spore germination
K8Z20_16110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z20_16120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z20_16130	COG0457	Tetratricopeptide repeat
K8Z20_16165	COG1404	Belongs to the peptidase S8 family
K8Z20_16195	COG0488	(ABC) transporter
K8Z20_16220	COG3852	Histidine kinase
K8Z20_16230	COG1285	pathogenesis
K8Z20_16240	COG2514	catechol 2,3-dioxygenase activity
K8Z20_16245	COG2720	vancomycin resistance protein
K8Z20_16280	COG0716	FMN binding
K8Z20_16315	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_16325	COG0165	Argininosuccinate lyase
K8Z20_16340	COG4145	pantothenate transmembrane transporter activity
K8Z20_16350	COG1012	belongs to the aldehyde dehydrogenase family
K8Z20_16355	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_16365	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z20_16370	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z20_16375	COG2962	Rard protein
K8Z20_16380	COG3326	Membrane
K8Z20_16395	COG0489	protein tyrosine kinase activity
K8Z20_16405	COG0314	molybdopterin synthase activity
K8Z20_16410	COG0303	'Molybdopterin
K8Z20_16415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z20_16420	COG2116	formate transmembrane transporter activity
K8Z20_16430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z20_16435	COG5609	conserved protein (DUF2294)
K8Z20_16440	COG2427	Protein of unknown function (DUF1641)
K8Z20_16445	COG3383	formate dehydrogenase (NAD+) activity
K8Z20_16450	COG0697	spore germination
K8Z20_16465	COG0531	amino acid
K8Z20_16500	COG2226	methyltransferase
K8Z20_16505	COG4166	transmembrane transport
K8Z20_16510	COG4166	transmembrane transport
K8Z20_16515	COG4166	transmembrane transport
K8Z20_16520	COG1316	TRANSCRIPTIONal
K8Z20_16530	COG1595	DNA-templated transcription, initiation
K8Z20_16540	COG1131	(ABC) transporter
K8Z20_16560	COG0673	inositol 2-dehydrogenase activity
K8Z20_16565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z20_16570	COG0187	DNA topoisomerase II activity
K8Z20_16575	COG1832	CoA-binding protein
K8Z20_16580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z20_16585	COG0745	RESPONSE REGULATOR receiver
K8Z20_16595	COG1328	CTP reductase activity
K8Z20_16595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K8Z20_16605	COG4841	protein insertion into membrane
K8Z20_16610	COG0824	Thioesterase
K8Z20_16645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z20_16660	COG1132	(ABC) transporter
K8Z20_16670	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z20_16700	COG2211	Major facilitator Superfamily
K8Z20_16710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z20_16725	COG0183	Belongs to the thiolase family
K8Z20_16730	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_16735	COG1268	BioY protein
K8Z20_16740	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_16745	COG1396	sequence-specific DNA binding
K8Z20_16775	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K8Z20_16795	COG0830	nickel cation binding
K8Z20_16835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_16845	COG5002	protein histidine kinase activity
K8Z20_16850	COG0400	carboxylic ester hydrolase activity
K8Z20_16855	COG0346	lactoylglutathione lyase activity
K8Z20_16865	COG0069	glutamate synthase activity
K8Z20_16870	COG1902	pentaerythritol trinitrate reductase activity
K8Z20_16875	COG1329	Transcriptional regulator
K8Z20_16880	COG0010	Belongs to the arginase family
K8Z20_16905	COG2226	methyltransferase
K8Z20_16930	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z20_16935	COG0785	Cytochrome C biogenesis protein
K8Z20_16945	COG1473	amidohydrolase
K8Z20_16960	COG1131	(ABC) transporter
K8Z20_16975	COG0583	DNA-binding transcription factor activity
K8Z20_16985	COG1346	cytolysis
K8Z20_17000	COG0730	response to heat
K8Z20_17025	COG1132	(ABC) transporter
K8Z20_17030	COG1132	(ABC) transporter
K8Z20_17065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z20_17070	COG0737	Belongs to the 5'-nucleotidase family
K8Z20_17080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z20_17100	COG1695	Transcriptional regulator
K8Z20_17110	COG0174	glutamine synthetase
K8Z20_17115	COG0789	Transcriptional regulator
K8Z20_17120	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z20_17125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z20_17130	COG2860	membrane
K8Z20_17140	COG0464	growth
K8Z20_17170	COG1388	LysM domain
K8Z20_17170	COG3584	3D domain protein
K8Z20_17180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z20_17180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z20_17180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z20_17185	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z20_17190	COG1349	DNA-binding transcription factor activity
K8Z20_17195	COG1979	alcohol dehydrogenase
K8Z20_17200	COG2322	membrane
K8Z20_17210	COG1113	amino acid transport
K8Z20_17225	COG2116	formate transmembrane transporter activity
K8Z20_17240	COG2217	Heavy metal translocating P-type atpase
K8Z20_17245	COG2608	mercury ion transmembrane transporter activity
K8Z20_17250	COG1937	Protein conserved in bacteria
K8Z20_17260	COG2819	hydrolase of the alpha beta superfamily
K8Z20_17265	COG1120	ATPase activity
K8Z20_17270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_17275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_17280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z20_17290	COG2169	Transcriptional regulator
K8Z20_17295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z20_17300	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z20_17320	COG2267	carboxylic ester hydrolase activity
K8Z20_17325	COG3300	MHYT domain
K8Z20_17325	COG5001	Diguanylate cyclase
K8Z20_17345	COG1086	Polysaccharide biosynthesis protein
K8Z20_17365	COG1346	cytolysis
K8Z20_17375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z20_17385	COG2188	Transcriptional regulator
K8Z20_17390	COG2723	6-phospho-beta-galactosidase activity
K8Z20_17395	COG0823	Involved in the tonB-independent uptake of proteins
K8Z20_17400	COG1404	Belongs to the peptidase S8 family
K8Z20_17405	COG3773	Cell wall hydrolase
K8Z20_17415	COG1368	sulfuric ester hydrolase activity
K8Z20_17420	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z20_17445	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z20_17455	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z20_17460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z20_17460	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z20_17470	COG2359	stage V sporulation protein S
K8Z20_17475	COG1692	metallophosphoesterase
K8Z20_17495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z20_17500	COG1426	Protein conserved in bacteria
K8Z20_17515	COG0300	oxidoreductase activity
K8Z20_17520	COG0612	Peptidase, M16
K8Z20_17525	COG0612	Peptidase, M16
K8Z20_17530	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z20_17535	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z20_17540	COG3845	ABC transporter
K8Z20_17545	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z20_17550	COG2188	Transcriptional regulator
K8Z20_17565	COG0740	serine-type endopeptidase activity
K8Z20_17575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z20_17585	COG0527	aspartate kinase activity
K8Z20_17590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z20_17595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z20_17600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z20_17605	COG1873	PFAM PRC-barrel domain
K8Z20_17610	COG0612	Peptidase, M16
K8Z20_17615	COG0726	polysaccharide deacetylase
K8Z20_17630	COG0196	riboflavin kinase activity
K8Z20_17640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z20_17645	COG1550	Protein conserved in bacteria
K8Z20_17655	COG1358	cellular component organization or biogenesis
K8Z20_17660	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z20_17665	COG0195	Participates in both transcription termination and antitermination
K8Z20_17685	COG0750	zinc metalloprotease
K8Z20_17695	COG4589	Belongs to the CDS family
K8Z20_17745	COG4974	Belongs to the 'phage' integrase family
K8Z20_17755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z20_17760	COG0758	DNA mediated transformation
K8Z20_17765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z20_17805	COG1837	Belongs to the UPF0109 family
K8Z20_17815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z20_17825	COG0552	protein localization to endoplasmic reticulum
K8Z20_17830	COG1196	nuclear chromosome segregation
K8Z20_17840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z20_17845	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_17850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z20_17865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z20_17870	COG1461	Dihydroxyacetone kinase
K8Z20_17875	COG1302	Protein conserved in bacteria
K8Z20_17890	COG1564	THIamine pyrophosphokinase
K8Z20_17895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z20_17905	COG0515	serine threonine protein kinase
K8Z20_17905	COG2815	serine threonine protein kinase
K8Z20_17910	COG0631	protein serine/threonine phosphatase activity
K8Z20_17920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z20_17920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z20_17935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z20_17940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z20_17960	COG1561	YicC-like family, N-terminal region
K8Z20_17965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z20_17975	COG0006	proline dipeptidase activity
K8Z20_17990	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z20_18050	COG0564	pseudouridine synthase activity
K8Z20_18070	COG3599	regulation of cell shape
K8Z20_18075	COG2302	S4 RNA-binding domain
K8Z20_18080	COG0762	integral membrane protein
K8Z20_18090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z20_18100	COG1873	PFAM PRC-barrel domain
K8Z20_18105	COG1191	sigma factor activity
K8Z20_18110	COG1191	sigma factor activity
K8Z20_18120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z20_18125	COG0849	cell division
K8Z20_18145	COG0772	Belongs to the SEDS family
K8Z20_18165	COG0768	penicillin binding
K8Z20_18170	COG0768	penicillin binding
K8Z20_18190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z20_18210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z20_18215	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z20_18325	COG0740	serine-type endopeptidase activity
K8Z20_18380	COG0582	viral genome integration into host DNA
K8Z20_18435	COG2002	toxin-antitoxin pair type II binding
K8Z20_18475	COG1396	sequence-specific DNA binding
K8Z20_18515	COG0582	viral genome integration into host DNA
K8Z20_18525	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z20_18530	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z20_18535	COG3314	Sporulation integral membrane protein YlbJ
K8Z20_18545	COG0742	ribosomal rna small subunit methyltransferase
K8Z20_18560	COG3679	Belongs to the UPF0342 family
K8Z20_18565	COG0406	alpha-ribazole phosphatase activity
K8Z20_18580	COG2340	Cysteine-rich secretory protein family
K8Z20_18595	COG3336	cytochrome c oxidase
K8Z20_18630	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z20_18635	COG0772	Belongs to the SEDS family
K8Z20_18645	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z20_18650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z20_18660	COG4896	Protein conserved in bacteria
K8Z20_18675	COG1217	gtp-binding protein TYPA
K8Z20_18685	COG0483	inositol monophosphate 1-phosphatase activity
K8Z20_18705	COG1982	Orn Lys Arg decarboxylase major
K8Z20_18755	COG0022	dehydrogenase e1 component
K8Z20_18760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z20_18775	COG0561	phosphatase activity
K8Z20_18785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z20_18790	COG0569	domain protein
K8Z20_18810	COG0583	DNA-binding transcription factor activity
K8Z20_18815	COG0517	IMP dehydrogenase activity
K8Z20_18825	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z20_18835	COG4703	Protein of unknown function (DUF1797)
K8Z20_18855	COG2200	EAL domain
K8Z20_18860	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_18865	COG1408	metallophosphoesterase
K8Z20_18910	COG2814	Major facilitator Superfamily
K8Z20_18930	COG3209	COG3209 Rhs family protein
K8Z20_18940	COG2205	protein histidine kinase activity
K8Z20_18950	COG0436	Aminotransferase
K8Z20_18955	COG1609	Transcriptional regulator
K8Z20_18960	COG3833	ABC-type maltose transport systems, permease component
K8Z20_18965	COG1175	transmembrane transport
K8Z20_18970	COG2182	Extracellular solute-binding protein
K8Z20_18980	COG0366	Alpha amylase catalytic
K8Z20_18985	COG3842	ATPase activity
K8Z20_19020	COG0183	Belongs to the thiolase family
K8Z20_19050	COG1695	Transcriptional regulator
K8Z20_19055	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_19075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z20_19080	COG0436	Aminotransferase
K8Z20_19115	COG2084	Dehydrogenase
K8Z20_19125	COG2199	diguanylate cyclase activity
K8Z20_19130	COG0778	Nitroreductase
K8Z20_19155	COG1263	PTS System
K8Z20_19155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z20_19155	COG2190	(PTS) system
K8Z20_19160	COG3711	transcriptional antiterminator
K8Z20_19170	COG2188	Transcriptional regulator
K8Z20_19180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z20_19205	COG1547	Domain of unknown function (DUF309)
K8Z20_19210	COG0456	acetyltransferase
K8Z20_19215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z20_19220	COG4086	secreted protein
K8Z20_19225	COG0561	phosphatase activity
K8Z20_19230	COG0697	spore germination
K8Z20_19245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z20_19290	COG1686	Belongs to the peptidase S11 family
K8Z20_19295	COG1725	Transcriptional regulator
K8Z20_19300	COG1131	(ABC) transporter
K8Z20_19315	COG1846	Transcriptional regulator
K8Z20_19330	COG0598	Magnesium transport protein CorA
K8Z20_19355	COG4974	Belongs to the 'phage' integrase family
K8Z20_19365	COG0735	belongs to the Fur family
K8Z20_19370	COG1300	Membrane
K8Z20_19390	COG0667	Aldo Keto reductase
K8Z20_19395	COG0656	L-ascorbic acid biosynthetic process
K8Z20_19400	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z20_19400	COG0456	acetyltransferase
K8Z20_19430	COG0596	Alpha beta hydrolase
K8Z20_19435	COG2056	Na+-H+ antiporter family
K8Z20_19440	COG1609	Transcriptional regulator
K8Z20_19445	COG0456	acetyltransferase
K8Z20_19450	COG1073	alpha beta
K8Z20_19465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z20_19465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z20_19470	COG0307	riboflavin synthase, alpha
K8Z20_19500	COG1073	alpha beta
K8Z20_19500	COG2226	methyltransferase
K8Z20_19515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z20_19525	COG1757	Na H antiporter
K8Z20_19530	COG0737	Belongs to the 5'-nucleotidase family
K8Z20_19540	COG1522	sequence-specific DNA binding
K8Z20_19585	COG0300	oxidoreductase activity
K8Z20_19590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_19595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z20_19600	COG1760	l-serine dehydratase
K8Z20_19605	COG1760	l-serine dehydratase
K8Z20_19635	COG1285	pathogenesis
K8Z20_19645	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z20_19650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_19665	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z20_19670	COG4129	membrane
K8Z20_19675	COG1126	abc transporter atp-binding protein
K8Z20_19680	COG0765	amino acid transport
K8Z20_19685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z20_19705	COG2323	membrane
K8Z20_19710	COG0772	Belongs to the SEDS family
K8Z20_19720	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z20_19725	COG0022	dehydrogenase e1 component
K8Z20_19730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z20_19735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z20_19750	COG0280	phosphate acetyltransferase
K8Z20_19755	COG3829	transcription factor binding
K8Z20_19755	COG3290	protein histidine kinase activity
K8Z20_19765	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z20_19770	COG3093	addiction module antidote protein HigA
K8Z20_19785	COG0750	zinc metalloprotease
K8Z20_19790	COG0497	DNA recombination
K8Z20_19800	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z20_19810	COG0142	geranyltranstransferase activity
K8Z20_19835	COG1302	Protein conserved in bacteria
K8Z20_19840	COG0439	Biotin carboxylase
K8Z20_19845	COG0511	ligase activity, forming carbon-carbon bonds
K8Z20_19890	COG3854	ATPases associated with a variety of cellular activities
K8Z20_19915	COG0006	proline dipeptidase activity
K8Z20_19930	COG3872	metal-dependent enzyme
K8Z20_19940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z20_19980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z20_19990	COG1609	Transcriptional regulator
K8Z20_20000	COG2076	Multidrug Resistance protein
K8Z20_20005	COG2076	Multidrug Resistance protein
K8Z20_20035	COG1131	(ABC) transporter
K8Z20_20040	COG1725	Transcriptional regulator
K8Z20_20070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z20_20155	COG4824	toxin secretion phage lysis holin
K8Z20_20230	COG0740	serine-type endopeptidase activity
K8Z20_20285	COG0582	viral genome integration into host DNA
K8Z20_20340	COG2002	toxin-antitoxin pair type II binding
K8Z20_20350	COG1484	DNA-dependent DNA replication
K8Z20_20375	COG3646	Phage regulatory protein
K8Z20_20385	COG1396	sequence-specific DNA binding
K8Z20_20430	COG1459	type II secretion system
K8Z20_20435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z20_20490	COG0646	methionine synthase
K8Z20_20490	COG1410	methionine synthase
K8Z20_20495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z20_20495	COG0646	methionine synthase
K8Z20_20500	COG0626	cystathionine gamma-synthase activity
K8Z20_20505	COG0626	cystathionine gamma-synthase activity
K8Z20_20525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_20535	COG1940	carbohydrate kinase activity
K8Z20_20540	COG4483	Protein conserved in bacteria
K8Z20_20545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z20_20550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z20_20555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z20_20560	COG0704	Plays a role in the regulation of phosphate uptake
K8Z20_20570	COG0573	inorganic phosphate transmembrane transporter activity
K8Z20_20575	COG0573	inorganic phosphate transmembrane transporter activity
K8Z20_20580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z20_20590	COG0768	penicillin binding
K8Z20_20595	COG0477	Major facilitator Superfamily
K8Z20_20600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z20_20610	COG5521	maltodextrose utilization protein MalA
K8Z20_20625	COG0735	belongs to the Fur family
K8Z20_20630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z20_20635	COG1121	(ABC) transporter
K8Z20_20640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_20670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z20_20675	COG2384	SAM-dependent methyltransferase
K8Z20_20685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z20_20690	COG0358	DNA primase activity
K8Z20_20705	COG0517	IMP dehydrogenase activity
K8Z20_20720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z20_20725	COG0295	cytidine deaminase activity
K8Z20_20730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z20_20740	COG1480	7TM receptor with intracellular HD hydrolase
K8Z20_20745	COG1702	phosphate starvation-inducible protein PhoH
K8Z20_20760	COG1610	YqeY-like protein
K8Z20_20765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z20_20770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z20_20775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z20_20805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z20_20810	COG1733	regulation of RNA biosynthetic process
K8Z20_20835	COG1466	dna polymerase III delta subunit
K8Z20_20845	COG2333	competence protein COMEC
K8Z20_20845	COG0658	competence protein
K8Z20_20850	COG2131	deaminase
K8Z20_20855	COG1555	photosystem II stabilization
K8Z20_20855	COG1596	polysaccharide export
K8Z20_20860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z20_20865	COG2226	methyltransferase
K8Z20_20870	COG0799	negative regulation of ribosome biogenesis
K8Z20_20875	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z20_20885	COG1534	Rna-binding protein
K8Z20_20895	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z20_20900	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z20_20935	COG0778	Nitroreductase
K8Z20_20940	COG2357	RelA SpoT domain protein
K8Z20_20950	COG1785	Belongs to the alkaline phosphatase family
K8Z20_20960	COG2267	carboxylic ester hydrolase activity
K8Z20_21005	COG3186	Phenylalanine-4-hydroxylase
K8Z20_21015	COG2514	catechol 2,3-dioxygenase activity
K8Z20_21020	COG2259	Doxx family
K8Z20_21060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z20_21070	COG1454	alcohol dehydrogenase
K8Z20_21070	COG1012	belongs to the aldehyde dehydrogenase family
K8Z20_21075	COG0626	cystathionine gamma-synthase activity
K8Z20_21080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z20_21130	COG0826	peptidase U32
K8Z20_21135	COG0826	peptidase U32
K8Z20_21140	COG4122	O-methyltransferase activity
K8Z20_21145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z20_21175	COG0628	permease
K8Z20_21195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z20_21210	COG1104	cysteine desulfurase activity
K8Z20_21215	COG1959	2 iron, 2 sulfur cluster binding
K8Z20_21220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z20_21230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z20_21255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z20_21265	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z20_21265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z20_21270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z20_21275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z20_21275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z20_21285	COG2244	polysaccharide biosynthetic process
K8Z20_21290	COG2323	membrane
K8Z20_21300	COG1862	Preprotein translocase
K8Z20_21330	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z20_21360	COG0157	Belongs to the NadC ModD family
K8Z20_21365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z20_21370	COG1104	cysteine desulfurase activity
K8Z20_21375	COG1827	regulation of RNA biosynthetic process
K8Z20_21380	COG2258	MOSC domain
K8Z20_21385	COG0077	Prephenate dehydratase
K8Z20_21390	COG0577	efflux transmembrane transporter activity
K8Z20_21395	COG0577	efflux transmembrane transporter activity
K8Z20_21400	COG1136	(ABC) transporter
K8Z20_21405	COG5002	protein histidine kinase activity
K8Z20_21410	COG0745	RESPONSE REGULATOR receiver
K8Z20_21420	COG3290	protein histidine kinase activity
K8Z20_21430	COG2868	ribosomal protein
K8Z20_21440	COG1530	ribonuclease E activity
K8Z20_21445	COG1994	Peptidase M50
K8Z20_21450	COG0739	heme binding
K8Z20_21455	COG2894	cell division
K8Z20_21475	COG1077	Cell shape determining protein MreB Mrl
K8Z20_21500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K8Z20_21530	COG2003	Belongs to the UPF0758 family
K8Z20_21560	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_21675	COG1595	DNA-templated transcription, initiation
K8Z20_21685	COG3331	DNA recombination
K8Z20_21765	COG3646	Phage regulatory protein
K8Z20_21785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z20_21805	COG0285	dihydrofolate synthase activity
K8Z20_21820	COG1388	LysM domain
K8Z20_21830	COG0113	porphobilinogen synthase activity
K8Z20_21835	COG1587	Uroporphyrinogen-III synthase
K8Z20_21845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z20_21855	COG1846	Transcriptional regulator
K8Z20_21860	COG1764	response to oxidative stress
K8Z20_21875	COG0470	DNA polymerase III
K8Z20_21875	COG1067	ATP-dependent peptidase activity
K8Z20_22015	COG0622	Phosphoesterase
K8Z20_22030	COG5401	PFAM Sporulation and spore germination
K8Z20_22045	COG2197	response regulator
K8Z20_22050	COG2233	PERMEase
K8Z20_22055	COG0402	S-adenosylhomocysteine deaminase activity
K8Z20_22060	COG1983	PspC domain protein
K8Z20_22065	COG1396	sequence-specific DNA binding
K8Z20_22070	COG0697	spore germination
K8Z20_22080	COG1959	2 iron, 2 sulfur cluster binding
K8Z20_22085	COG1668	transmembrane transport
K8Z20_22090	COG4152	abc transporter atp-binding protein
K8Z20_22095	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z20_22100	COG1360	Flagellar Motor Protein
K8Z20_22105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z20_22110	COG1876	peptidase activity
K8Z20_22115	COG0824	Thioesterase
K8Z20_22120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z20_22125	COG1053	succinate dehydrogenase
K8Z20_22130	COG2009	succinate dehydrogenase
K8Z20_22135	COG1719	4-vinyl reductase, 4VR
K8Z20_22145	COG3118	belongs to the thioredoxin family
K8Z20_22150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z20_22155	COG2086	electron transfer activity
K8Z20_22160	COG1024	Enoyl-CoA hydratase
K8Z20_22165	COG1309	transcriptional regulator
K8Z20_22170	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_22195	COG2318	DinB family
K8Z20_22225	COG1131	(ABC) transporter
K8Z20_22230	COG2205	protein histidine kinase activity
K8Z20_22235	COG0745	RESPONSE REGULATOR receiver
K8Z20_22245	COG4895	conserved protein (DUF2196)
K8Z20_22250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z20_22260	COG4509	Sortase family
K8Z20_22265	COG1120	ATPase activity
K8Z20_22280	COG5386	Cell surface protein
K8Z20_22290	COG5386	Cell surface protein
K8Z20_22295	COG1114	Component of the transport system for branched-chain amino acids
K8Z20_22300	COG1187	pseudouridine synthase activity
K8Z20_22310	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z20_22310	COG1796	DNA polymerase
K8Z20_22315	COG1286	toxin biosynthetic process
K8Z20_22360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z20_22370	COG1418	mRNA catabolic process
K8Z20_22390	COG2814	Major facilitator Superfamily
K8Z20_22395	COG1566	PFAM secretion protein HlyD family protein
K8Z20_22400	COG1309	transcriptional regulator
K8Z20_22405	COG1363	Peptidase, m42
K8Z20_22430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z20_22445	COG1484	DNA-dependent DNA replication
K8Z20_22450	COG3611	Membrane attachment protein
K8Z20_22460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z20_22465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z20_22475	COG1971	Probably functions as a manganese efflux pump
K8Z20_22485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z20_22485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z20_22490	COG5002	protein histidine kinase activity
K8Z20_22495	COG0745	RESPONSE REGULATOR receiver
K8Z20_22515	COG0538	isocitrate dehydrogenase activity
K8Z20_22520	COG0372	Belongs to the citrate synthase family
K8Z20_22530	COG0628	permease
K8Z20_22535	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z20_22560	COG1725	Transcriptional regulator
K8Z20_22565	COG0281	malic enzyme
K8Z20_22570	COG0587	DNA-directed DNA polymerase activity
K8Z20_22585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z20_22600	COG4109	DRTGG domain
K8Z20_22615	COG0006	proline dipeptidase activity
K8Z20_22655	COG0662	Cupin 2, conserved barrel domain protein
K8Z20_22670	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_22675	COG0589	response to stress
K8Z20_22720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_22745	COG0827	DNA restriction-modification system
K8Z20_22750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z20_22755	COG3874	Sporulation protein YtfJ
K8Z20_22770	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z20_22780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z20_22795	COG1104	cysteine desulfurase activity
K8Z20_22805	COG0583	DNA-binding transcription factor activity
K8Z20_22810	COG0697	spore germination
K8Z20_22815	COG1309	transcriptional regulator
K8Z20_22820	COG1956	GAF domain-containing protein
K8Z20_22825	COG0626	cystathionine gamma-synthase activity
K8Z20_22875	COG1595	DNA-templated transcription, initiation
K8Z20_22885	COG0110	maltose O-acetyltransferase activity
K8Z20_22890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z20_22895	COG0454	-acetyltransferase
K8Z20_22900	COG0517	IMP dehydrogenase activity
K8Z20_22905	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z20_22920	COG0745	RESPONSE REGULATOR receiver
K8Z20_22930	COG0666	response to abiotic stimulus
K8Z20_22935	COG2972	Histidine kinase
K8Z20_22935	COG0745	RESPONSE REGULATOR receiver
K8Z20_22955	COG3279	Response regulator of the LytR AlgR family
K8Z20_22990	COG1609	Transcriptional regulator
K8Z20_22995	COG1605	Chorismate mutase
K8Z20_22995	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z20_23000	COG4851	CamS sex pheromone cAM373 precursor
K8Z20_23005	COG3118	belongs to the thioredoxin family
K8Z20_23015	COG2309	aminopeptidase activity
K8Z20_23030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_23045	COG1674	ftsk spoiiie
K8Z20_23060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z20_23070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z20_23075	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z20_23080	COG1363	Peptidase, m42
K8Z20_23090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_23105	COG0510	thiamine kinase activity
K8Z20_23110	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z20_23120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z20_23125	COG1349	DNA-binding transcription factor activity
K8Z20_23130	COG1187	pseudouridine synthase activity
K8Z20_23135	COG2244	polysaccharide biosynthetic process
K8Z20_23140	COG2081	HI0933 family
K8Z20_23145	COG2814	Major facilitator Superfamily
K8Z20_23155	COG3832	glyoxalase III activity
K8Z20_23175	COG1329	Transcriptional regulator
K8Z20_23200	COG0314	molybdopterin synthase activity
K8Z20_23205	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z20_23210	COG0303	'Molybdopterin
K8Z20_23220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z20_23225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z20_23245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z20_23255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z20_23300	COG2814	Major facilitator Superfamily
K8Z20_23305	COG0475	glutathione-regulated potassium exporter activity
K8Z20_23310	COG0490	domain, Protein
K8Z20_23315	COG0582	viral genome integration into host DNA
K8Z20_23325	COG1136	(ABC) transporter
K8Z20_23345	COG1242	4 iron, 4 sulfur cluster binding
K8Z20_23350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z20_23355	COG1794	racemase activity, acting on amino acids and derivatives
K8Z20_23375	COG2267	carboxylic ester hydrolase activity
K8Z20_23380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z20_23385	COG0671	phosphoesterase, PA-phosphatase related
K8Z20_23390	COG0438	transferase activity, transferring glycosyl groups
K8Z20_23410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_23450	COG0546	phosphoglycolate phosphatase activity
K8Z20_23455	COG1349	DNA-binding transcription factor activity
K8Z20_23470	COG5002	protein histidine kinase activity
K8Z20_23475	COG3852	Histidine kinase
K8Z20_23480	COG2267	carboxylic ester hydrolase activity
K8Z20_23485	COG1368	sulfuric ester hydrolase activity
K8Z20_23510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z20_23515	COG1116	anion transmembrane transporter activity
K8Z20_23520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z20_23545	COG0494	nUDIX hydrolase
K8Z20_23575	COG1854	S-ribosylhomocysteine lyase activity
K8Z20_23590	COG1271	oxidase subunit
K8Z20_23595	COG1294	oxidase, subunit
K8Z20_23605	COG2801	Transposase and inactivated derivatives
K8Z20_23620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_23640	COG1842	Phage shock protein A
K8Z20_23675	COG5002	protein histidine kinase activity
K8Z20_23680	COG0745	RESPONSE REGULATOR receiver
K8Z20_23705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z20_23710	COG1597	lipid kinase activity
K8Z20_23735	COG0586	Pfam SNARE associated Golgi protein
K8Z20_23745	COG0577	efflux transmembrane transporter activity
K8Z20_23750	COG1136	(ABC) transporter
K8Z20_23755	COG2207	Transcriptional regulator
K8Z20_23755	COG3708	Transcriptional regulator
K8Z20_23765	COG5658	integral membrane protein
K8Z20_23770	COG0640	Transcriptional regulator
K8Z20_23775	COG0745	RESPONSE REGULATOR receiver
K8Z20_23780	COG2205	protein histidine kinase activity
K8Z20_23785	COG0577	efflux transmembrane transporter activity
K8Z20_23790	COG0577	efflux transmembrane transporter activity
K8Z20_23795	COG1136	(ABC) transporter
K8Z20_23800	COG0577	efflux transmembrane transporter activity
K8Z20_23830	COG2188	Transcriptional regulator
K8Z20_23850	COG3964	amidohydrolase
K8Z20_23870	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z20_23895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z20_23900	COG0596	Alpha beta hydrolase
K8Z20_23910	COG1169	isochorismate synthase
K8Z20_23915	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z20_23920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z20_23945	COG0058	SHG alpha-glucan phosphorylase activity
K8Z20_23955	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z20_24075	COG0544	peptidyl-prolyl cis-trans isomerase activity
K8Z20_24110	COG1285	pathogenesis
K8Z20_24115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z20_24130	COG2155	Conserved Protein
K8Z20_24135	COG1098	S1 RNA binding domain
K8Z20_24140	COG0436	Aminotransferase
K8Z20_24150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z20_24155	COG2267	carboxylic ester hydrolase activity
K8Z20_24165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z20_24185	COG5018	Exonuclease
K8Z20_24190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z20_24215	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z20_24225	COG1268	BioY protein
K8Z20_24230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z20_24235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z20_24250	COG3584	3D domain protein
K8Z20_24265	COG1252	NADH dehydrogenase
K8Z20_24295	COG1683	Conserved Protein
K8Z20_24350	COG1388	LysM domain
K8Z20_24350	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_24350	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_24355	COG4824	toxin secretion phage lysis holin
K8Z20_24490	COG1191	sigma factor activity
K8Z20_24515	COG3646	Phage regulatory protein
K8Z20_24515	COG3645	SOS response
K8Z20_24530	COG3620	sequence-specific DNA binding
K8Z20_24565	COG0316	Belongs to the HesB IscA family
K8Z20_24580	COG1252	NADH dehydrogenase
K8Z20_24595	COG0390	transport system, permease component
K8Z20_24600	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z20_24645	COG4837	Protein of unknown function (DUF1462)
K8Z20_24650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z20_24660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z20_24665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z20_24685	COG1358	cellular component organization or biogenesis
K8Z20_24695	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z20_24700	COG0647	UMP catabolic process
K8Z20_24710	COG2445	Protein of unknown function DUF86
K8Z20_24715	COG1494	fructose-1,6-bisphosphatase
K8Z20_24735	COG4470	Protein conserved in bacteria
K8Z20_24745	COG0789	Transcriptional regulator
K8Z20_24750	COG4377	Putative membrane peptidase family (DUF2324)
K8Z20_24775	COG0739	heme binding
K8Z20_24785	COG3377	Domain of unknown function (DUF1805)
K8Z20_24790	COG0737	Belongs to the 5'-nucleotidase family
K8Z20_24795	COG2801	Transposase and inactivated derivatives
K8Z20_24820	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_24960	COG1396	sequence-specific DNA binding
K8Z20_25040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z20_25045	COG0582	viral genome integration into host DNA
K8Z20_25050	COG0719	Fe-S assembly protein
K8Z20_25055	COG0822	iron-sulfur transferase activity
K8Z20_25060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z20_25065	COG0719	Fe-S assembly protein
K8Z20_25070	COG0396	ATPase activity
K8Z20_25075	COG1464	Belongs to the NlpA lipoprotein family
K8Z20_25080	COG1464	Belongs to the NlpA lipoprotein family
K8Z20_25085	COG2011	ABC-type metal ion transport system permease component
K8Z20_25100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z20_25105	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z20_25115	COG1393	Belongs to the ArsC family
K8Z20_25135	COG0039	L-malate dehydrogenase activity
K8Z20_25150	COG1309	transcriptional regulator
K8Z20_25155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z20_25160	COG1960	acyl-CoA dehydrogenase activity
K8Z20_25165	COG0183	Belongs to the thiolase family
K8Z20_25170	COG1024	Enoyl-CoA hydratase
K8Z20_25170	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z20_25180	COG1686	Belongs to the peptidase S11 family
K8Z20_25195	COG0011	TIGRFAM Protein of
K8Z20_25200	COG0840	transmembrane signaling receptor activity
K8Z20_25215	COG2814	Major facilitator Superfamily
K8Z20_25220	COG0531	amino acid
K8Z20_25240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_25275	COG0586	Pfam SNARE associated Golgi protein
K8Z20_25285	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z20_25290	COG0745	RESPONSE REGULATOR receiver
K8Z20_25295	COG5002	protein histidine kinase activity
K8Z20_25325	COG0840	transmembrane signaling receptor activity
K8Z20_25330	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z20_25375	COG3227	Zinc metalloprotease (Elastase)
K8Z20_25395	COG0586	Pfam SNARE associated Golgi protein
K8Z20_25400	COG0475	glutathione-regulated potassium exporter activity
K8Z20_25405	COG0490	domain, Protein
K8Z20_25410	COG1115	amino acid carrier protein
K8Z20_25415	COG0783	Belongs to the Dps family
K8Z20_25430	COG1611	Belongs to the LOG family
K8Z20_25440	COG1528	Iron-storage protein
K8Z20_25445	COG2311	Membrane
K8Z20_25450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z20_25455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z20_25460	COG1115	amino acid carrier protein
K8Z20_25465	COG1115	amino acid carrier protein
K8Z20_25470	COG2910	NAD(P)H-binding
K8Z20_25485	COG0656	L-ascorbic acid biosynthetic process
K8Z20_25490	COG2814	Major facilitator Superfamily
K8Z20_25495	COG1733	regulation of RNA biosynthetic process
K8Z20_25505	COG1252	NADH dehydrogenase
K8Z20_25560	COG0488	(ABC) transporter
K8Z20_25565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_25610	COG0745	RESPONSE REGULATOR receiver
K8Z20_25650	COG0557	exoribonuclease II activity
K8Z20_25655	COG1647	Serine aminopeptidase, S33
K8Z20_25660	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z20_25665	COG1346	cytolysis
K8Z20_25700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z20_25715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z20_25740	COG1388	LysM domain
K8Z20_25740	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_25740	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_25745	COG4824	toxin secretion phage lysis holin
K8Z20_25880	COG3331	DNA recombination
K8Z20_25965	COG3646	Phage regulatory protein
K8Z20_25995	COG0582	viral genome integration into host DNA
K8Z20_26020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z20_26035	COG2323	membrane
K8Z20_26045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z20_26055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z20_26065	COG1051	belongs to the nudix hydrolase family
K8Z20_26075	COG0492	ferredoxin-NADP+ reductase activity
K8Z20_26095	COG0110	maltose O-acetyltransferase activity
K8Z20_26115	COG1950	PFAM Membrane protein of
K8Z20_26125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z20_26130	COG0556	nucleotide-excision repair
K8Z20_26145	COG0789	Transcriptional regulator
K8Z20_26165	COG0583	DNA-binding transcription factor activity
K8Z20_26175	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z20_26180	COG0488	(ABC) transporter
K8Z20_26190	COG1132	(ABC) transporter
K8Z20_26195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z20_26200	COG0793	Belongs to the peptidase S41A family
K8Z20_26200	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_26205	COG2177	Part of the ABC transporter FtsEX involved in
K8Z20_26210	COG2884	Cell division ATP-binding protein ftsE
K8Z20_26235	COG1131	(ABC) transporter
K8Z20_26265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z20_26270	COG1278	Cold shock
K8Z20_26275	COG1040	competence protein
K8Z20_26280	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z20_26285	COG1388	LysM domain
K8Z20_26285	COG0791	NLP P60 protein
K8Z20_26290	COG1733	regulation of RNA biosynthetic process
K8Z20_26295	COG1307	EDD domain protein, DegV family
K8Z20_26300	COG1739	Uncharacterized protein family UPF0029
K8Z20_26305	COG1316	TRANSCRIPTIONal
K8Z20_26310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z20_26315	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z20_26320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z20_26330	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z20_26330	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z20_26350	COG1486	melibiose metabolic process
K8Z20_26355	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z20_26360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z20_26370	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z20_26380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z20_26385	COG1301	dicarboxylic acid transport
K8Z20_26400	COG1511	domain protein
K8Z20_26405	COG0583	DNA-binding transcription factor activity
K8Z20_26410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K8Z20_26420	COG1271	oxidase subunit
K8Z20_26425	COG1294	oxidase, subunit
K8Z20_26430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z20_26440	COG1620	l-lactate permease
K8Z20_26455	COG2389	metal-binding protein
K8Z20_26465	COG1368	sulfuric ester hydrolase activity
K8Z20_26480	COG1388	LysM domain
K8Z20_26480	COG0791	NLP P60 protein
K8Z20_26485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z20_26500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z20_26505	COG1388	LysM domain
K8Z20_26505	COG3584	3D domain protein
K8Z20_26530	COG4715	Zinc finger, swim domain protein
K8Z20_26535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z20_26575	COG0577	efflux transmembrane transporter activity
K8Z20_26580	COG1136	(ABC) transporter
K8Z20_26605	COG5002	protein histidine kinase activity
K8Z20_26610	COG0745	RESPONSE REGULATOR receiver
K8Z20_26620	COG1316	TRANSCRIPTIONal
K8Z20_26625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z20_26630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z20_26635	COG1215	transferase activity, transferring glycosyl groups
K8Z20_26640	COG0463	Glycosyl transferase, family 2
K8Z20_26645	COG0438	transferase activity, transferring glycosyl groups
K8Z20_26655	COG1216	Glycosyl transferase, family 2
K8Z20_26670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z20_26675	COG4464	protein tyrosine phosphatase activity
K8Z20_26680	COG0489	protein tyrosine kinase activity
K8Z20_26685	COG3944	biosynthesis protein
K8Z20_26690	COG0489	protein tyrosine kinase activity
K8Z20_26705	COG1609	Transcriptional regulator
K8Z20_26715	COG0739	heme binding
K8Z20_26730	COG3279	Response regulator of the LytR AlgR family
K8Z20_26735	COG2385	sporulation resulting in formation of a cellular spore
K8Z20_26750	COG4836	Membrane
K8Z20_26755	COG1007	ATP synthesis coupled electron transport
K8Z20_26760	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z20_26765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z20_26775	COG0839	Belongs to the complex I subunit 6 family
K8Z20_26795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z20_26810	COG3300	MHYT domain
K8Z20_26810	COG5001	Diguanylate cyclase
K8Z20_26860	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z20_26895	COG0698	ribose 5-phosphate isomerase
K8Z20_26910	COG2259	Doxx family
K8Z20_26915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z20_26930	COG0009	L-threonylcarbamoyladenylate synthase
K8Z20_26965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z20_26970	COG1494	fructose-1,6-bisphosphatase
K8Z20_26990	COG4821	SIS domain
K8Z20_27000	COG3343	RNA polymerase activity
K8Z20_27010	COG1960	acyl-CoA dehydrogenase activity
K8Z20_27015	COG1960	acyl-CoA dehydrogenase activity
K8Z20_27020	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z20_27025	COG0183	Belongs to the thiolase family
K8Z20_27030	COG2181	nitrate reductase activity
K8Z20_27030	COG0247	lactate metabolic process
K8Z20_27035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z20_27045	COG3300	MHYT domain
K8Z20_27045	COG5001	Diguanylate cyclase
K8Z20_27060	COG3227	Zinc metalloprotease (Elastase)
K8Z20_27065	COG2197	response regulator
K8Z20_27070	COG4585	Histidine kinase
K8Z20_27075	COG0842	Transport permease protein
K8Z20_27080	COG1131	(ABC) transporter
K8Z20_27085	COG0024	Methionine aminopeptidase
K8Z20_27105	COG2234	aminopeptidase activity
K8Z20_27125	COG1595	DNA-templated transcription, initiation
K8Z20_27135	COG4506	Protein conserved in bacteria
K8Z20_27140	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z20_27165	COG2814	Major facilitator Superfamily
K8Z20_27170	COG0789	Transcriptional regulator
K8Z20_27175	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z20_27180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z20_27190	COG1994	Peptidase M50
K8Z20_27200	COG1078	dGTPase activity
K8Z20_27205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z20_27215	COG2801	Transposase and inactivated derivatives
K8Z20_27220	COG1120	ATPase activity
K8Z20_27225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_27230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z20_27250	COG0280	phosphate acetyltransferase
K8Z20_27265	COG3773	Cell wall hydrolase
K8Z20_27275	COG2363	Small membrane protein
K8Z20_27285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z20_27290	COG2233	PERMEase
K8Z20_27295	COG0561	phosphatase activity
K8Z20_27300	COG2814	Major facilitator Superfamily
K8Z20_27315	COG1131	(ABC) transporter
K8Z20_27320	COG2755	lipolytic protein G-D-S-L family
K8Z20_27325	COG1609	Transcriptional regulator
K8Z20_27335	COG0460	homoserine dehydrogenase
K8Z20_27345	COG2873	o-acetylhomoserine
K8Z20_27355	COG1011	Hydrolase
K8Z20_27360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z20_27370	COG2197	response regulator
K8Z20_27375	COG2203	Gaf domain
K8Z20_27375	COG4585	Histidine kinase
K8Z20_27380	COG0351	phosphomethylpyrimidine kinase
K8Z20_27385	COG3706	GGDEF domain
K8Z20_27390	COG2879	small protein
K8Z20_27395	COG1966	Carbon starvation protein
K8Z20_27400	COG3279	Response regulator of the LytR AlgR family
K8Z20_27405	COG0477	Major facilitator Superfamily
K8Z20_27415	COG0438	transferase activity, transferring glycosyl groups
K8Z20_27430	COG0840	transmembrane signaling receptor activity
K8Z20_27440	COG1607	acyl-coa hydrolase
K8Z20_27445	COG1216	Glycosyl transferase, family 2
K8Z20_27460	COG1216	Glycosyl transferase, family 2
K8Z20_27470	COG4485	Bacterial membrane protein, YfhO
K8Z20_27475	COG0463	Glycosyl transferase, family 2
K8Z20_27480	COG0488	(ABC) transporter
K8Z20_27485	COG1309	transcriptional regulator
K8Z20_27490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z20_27500	COG0628	permease
K8Z20_27520	COG3275	phosphorelay sensor kinase activity
K8Z20_27525	COG2814	Major facilitator Superfamily
K8Z20_27530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z20_27565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z20_27570	COG1272	protein, Hemolysin III
K8Z20_27605	COG5002	protein histidine kinase activity
K8Z20_27620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z20_27625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z20_27630	COG4853	Protein conserved in bacteria
K8Z20_27640	COG5002	protein histidine kinase activity
K8Z20_27645	COG0745	RESPONSE REGULATOR receiver
K8Z20_27675	COG0305	Participates in initiation and elongation during chromosome replication
K8Z20_27685	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z20_27690	COG4241	membrane
K8Z20_27710	COG0012	GTP binding
K8Z20_27715	COG4481	Protein conserved in bacteria
K8Z20_27720	COG0668	transmembrane transport
K8Z20_27730	COG1475	DNA binding
K8Z20_27735	COG1192	Involved in chromosome partitioning
K8Z20_27760	COG1847	R3H domain protein
K8Z20_27775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z20_27785	COG0592	DNA-directed DNA polymerase activity
K8Z20_27790	COG2501	S4 domain
K8Z20_27800	COG0187	DNA topoisomerase II activity
K8Z20_27805	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z20_27840	COG0516	GMP reductase activity
K8Z20_27840	COG0517	IMP dehydrogenase activity
K8Z20_27845	COG1686	Belongs to the peptidase S11 family
K8Z20_27875	COG1428	Deoxynucleoside kinase
K8Z20_27880	COG1428	Deoxynucleoside kinase
K8Z20_27885	COG1335	isochorismatase
K8Z20_27890	COG0590	tRNA wobble adenosine to inosine editing
K8Z20_27900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z20_27955	COG1982	Orn Lys Arg decarboxylase major
K8Z20_27965	COG0470	DNA polymerase III
K8Z20_27970	COG1774	PSP1 C-terminal conserved region
K8Z20_27980	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z20_27990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z20_27995	COG2002	toxin-antitoxin pair type II binding
K8Z20_28005	COG0084	hydrolase, TatD family'
K8Z20_28025	COG4466	Protein conserved in bacteria
K8Z20_28040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z20_28045	COG0251	oxidation-reduction process
K8Z20_28075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z20_28080	COG2002	toxin-antitoxin pair type II binding
K8Z20_28085	COG2244	polysaccharide biosynthetic process
K8Z20_28090	COG3956	TIGRFAM MazG family protein
K8Z20_28095	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z20_28115	COG1098	S1 RNA binding domain
K8Z20_28130	COG2208	phosphoserine phosphatase activity
K8Z20_28140	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z20_28145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z20_28160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z20_28165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z20_28170	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z20_28175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z20_28180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z20_28185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z20_28190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z20_28195	COG1396	sequence-specific DNA binding
K8Z20_28200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z20_28290	COG3880	PFAM UvrB UvrC protein
K8Z20_28300	COG0542	response to heat
K8Z20_28305	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z20_28315	COG4956	integral membrane protein (PIN domain superfamily)
K8Z20_28335	COG1045	serine acetyltransferase
K8Z20_28350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z20_28355	COG3688	RNA-binding protein containing a PIN domain
K8Z20_28370	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z20_28375	COG0250	Participates in transcription elongation, termination and antitermination
K8Z20_28380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z20_28400	COG2813	Specifically methylates the guanine in position
K8Z20_28415	COG1358	cellular component organization or biogenesis
K8Z20_28420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z20_28485	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z20_28545	COG0201	protein transport
K8Z20_28555	COG0024	Methionine aminopeptidase
K8Z20_28565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z20_28600	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z20_28625	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z20_28630	COG0489	protein tyrosine kinase activity
K8Z20_28640	COG2194	sulfuric ester hydrolase activity
K8Z20_28645	COG0726	polysaccharide deacetylase
K8Z20_28725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z20_28730	COG4856	YbbR-like protein
K8Z20_28765	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_28770	COG2011	ABC-type metal ion transport system permease component
K8Z20_28775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z20_28780	COG1464	Belongs to the NlpA lipoprotein family
K8Z20_28785	COG0604	alcohol dehydrogenase
K8Z20_28795	COG0277	FAD linked oxidase domain protein
K8Z20_28800	COG2271	Major facilitator Superfamily
K8Z20_28810	COG2814	Major facilitator Superfamily
K8Z20_28825	COG2207	Transcriptional regulator
K8Z20_28840	COG4166	transmembrane transport
K8Z20_28845	COG4166	transmembrane transport
K8Z20_28850	COG0656	L-ascorbic acid biosynthetic process
K8Z20_28865	COG4149	molybdate abc transporter
K8Z20_28870	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z20_28875	COG1910	domain protein
K8Z20_28890	COG0697	spore germination
K8Z20_28905	COG0204	Acyl-transferase
K8Z20_28915	COG1609	Transcriptional regulator
K8Z20_28925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_28945	COG5298	Protein conserved in bacteria
K8Z20_28965	COG0488	(ABC) transporter
K8Z20_28975	COG0747	negative chemotaxis
K8Z20_28980	COG0601	transmembrane transport
K8Z20_28985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z20_28990	COG0444	Belongs to the ABC transporter superfamily
K8Z20_28995	COG4608	Belongs to the ABC transporter superfamily
K8Z20_29005	COG0561	phosphatase activity
K8Z20_29025	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z20_29030	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z20_29040	COG0531	amino acid
K8Z20_29045	COG2814	Major facilitator Superfamily
K8Z20_29055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z20_29065	COG4294	response to UV
K8Z20_29070	COG0705	Rhomboid family
K8Z20_29080	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z20_29085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z20_29090	COG0864	Transcriptional regulator
K8Z20_29095	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z20_29100	COG2183	response to ionizing radiation
K8Z20_29200	COG0802	atpase or kinase
K8Z20_29205	COG1214	PFAM Peptidase M22, glycoprotease
K8Z20_29210	COG0456	acetyltransferase
K8Z20_29220	COG0488	(ABC) transporter
K8Z20_29235	COG1266	CAAX protease self-immunity
K8Z20_29255	COG0582	viral genome integration into host DNA
K8Z20_29400	COG3331	DNA recombination
K8Z20_29465	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K8Z20_29470	COG1687	branched-chain amino acid
K8Z20_29495	COG2233	PERMEase
K8Z20_29500	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z20_29505	COG0288	reversible hydration of carbon dioxide
K8Z20_29510	COG1522	sequence-specific DNA binding
K8Z20_29540	COG0542	response to heat
K8Z20_29545	COG0494	nUDIX hydrolase
K8Z20_29550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K8Z20_29565	COG0457	Tetratricopeptide repeat
K8Z20_29700	COG3344	reverse transcriptase
K8Z20_29715	COG3344	reverse transcriptase
K8Z20_29915	COG2814	Major facilitator Superfamily
K8Z20_29950	COG3344	reverse transcriptase
K8Z20_29970	COG3344	reverse transcriptase
K8Z20_30040	COG2311	Membrane
K8Z20_30100	COG2801	Transposase and inactivated derivatives
K8Z20_30105	COG0457	Tetratricopeptide repeat
K8Z20_30125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z20_30155	COG2002	toxin-antitoxin pair type II binding
K8Z20_30160	COG4166	transmembrane transport
K8Z20_30180	COG4974	Belongs to the 'phage' integrase family
K8Z20_30250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K8Z20_30255	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z20_30270	COG4824	toxin secretion phage lysis holin
K8Z20_30295	COG5444	nuclease activity
K8Z20_30340	COG4974	Belongs to the 'phage' integrase family
K8Z20_30355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z20_30370	COG1073	alpha beta
K8Z20_30385	COG3104	oligopeptide transport
K8Z20_30415	COG0457	Tetratricopeptide repeat
K8Z20_30435	COG4974	Belongs to the 'phage' integrase family
K8Z20_30515	COG1132	(ABC) transporter
K8Z20_30520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z20_30530	COG1131	(ABC) transporter
K8Z20_30550	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8Z20_30590	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_30590	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_30600	COG3227	Zinc metalloprotease (Elastase)
K8Z20_30615	COG3011	Protein conserved in bacteria
K8Z20_30630	COG0457	Tetratricopeptide repeat
K8Z20_30665	COG1132	(ABC) transporter
K8Z20_30685	COG1475	DNA binding
K8Z20_30740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z20_30745	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_30745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z20_30745	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_30745	COG3321	synthase
K8Z20_30745	COG0300	oxidoreductase activity
K8Z20_30760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z20_30765	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z20_30780	COG1960	acyl-CoA dehydrogenase activity
K8Z20_30800	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_30800	COG0300	oxidoreductase activity
K8Z20_30800	COG3321	synthase
K8Z20_30800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z20_30800	COG0300	oxidoreductase activity
K8Z20_30800	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_30800	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z20_30800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z20_30800	COG3321	synthase
K8Z20_30800	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z20_30855	COG0667	Aldo Keto reductase
K8Z20_30880	COG1396	sequence-specific DNA binding
K8Z20_30895	COG1216	Glycosyl transferase, family 2
K8Z20_30900	COG1024	Enoyl-CoA hydratase
K8Z20_30920	COG1484	DNA-dependent DNA replication
K8Z20_31075	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_31095	COG0739	heme binding
K8Z20_31100	COG0741	lytic transglycosylase activity
K8Z20_31130	COG1361	Conserved repeat domain
K8Z20_31150	COG3344	reverse transcriptase
K8Z20_31195	COG2311	Membrane
K8Z20_31215	COG0457	Tetratricopeptide repeat
K8Z20_31240	COG0583	DNA-binding transcription factor activity
K8Z20_31245	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z20_31290	COG0730	response to heat
K8Z20_31315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z20_31340	COG2002	toxin-antitoxin pair type II binding
K8Z20_31345	COG4166	transmembrane transport
K8Z20_31365	COG4974	Belongs to the 'phage' integrase family
K8Z20_31395	COG0583	DNA-binding transcription factor activity
K8Z20_31400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_31405	COG0402	S-adenosylhomocysteine deaminase activity
K8Z20_31480	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z20_31495	COG4824	toxin secretion phage lysis holin
K8Z20_31535	COG0840	transmembrane signaling receptor activity
K8Z20_31540	COG5001	Diguanylate cyclase
K8Z20_31540	COG3300	MHYT domain
K8Z20_31570	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_31570	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_31575	COG0475	glutathione-regulated potassium exporter activity
K8Z20_31580	COG0490	domain, Protein
K8Z20_31585	COG0840	transmembrane signaling receptor activity
K8Z20_31640	COG0583	DNA-binding transcription factor activity
K8Z20_31650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z20_31685	COG0640	Transcriptional regulator
K8Z20_31730	COG0675	Transposase, IS605 OrfB family
K8Z20_31740	COG2828	Protein conserved in bacteria
K8Z20_31775	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z20_31810	COG0457	Tetratricopeptide repeat
K8Z20_31915	COG1136	(ABC) transporter
K8Z20_32170	COG0592	DNA-directed DNA polymerase activity
K8Z20_32175	COG4712	double-strand break repair protein
K8Z20_32210	COG3344	reverse transcriptase
K8Z20_32220	COG3344	reverse transcriptase
K8Z20_32460	COG0741	lytic transglycosylase activity
K8Z20_32460	COG0791	NLP P60 protein
K8Z20_32635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z20_32695	COG1923	regulation of RNA biosynthetic process
K8Z20_32705	COG0457	Tetratricopeptide repeat
K8Z20_32930	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z20_32955	COG0739	heme binding
K8Z20_33000	COG0457	Tetratricopeptide repeat
K8Z20_33260	COG0791	NLP P60 protein
K8Z20_33260	COG0741	lytic transglycosylase activity
K8Z20_33415	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_33415	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_33515	COG1073	alpha beta
K8Z20_33525	COG2197	response regulator
K8Z20_33530	COG1476	TRANSCRIPTIONal
K8Z20_33595	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z20_33760	COG3331	DNA recombination
K8Z20_33905	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z20_33905	COG3409	Peptidoglycan-binding domain 1 protein
K8Z20_33905	COG1388	LysM domain
K8Z20_33960	COG1396	sequence-specific DNA binding
K8Z20_34015	COG0457	Tetratricopeptide repeat
K8Z20_34135	COG0582	viral genome integration into host DNA
K8Z20_34145	COG3654	unkown
K8Z20_34150	COG3344	reverse transcriptase
K8Z20_34175	COG0501	Belongs to the peptidase M48B family
K8Z20_34190	COG0457	Tetratricopeptide repeat
K8Z20_34250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD