locus-tag	class	description
K8Z42_00005	COG1802	Transcriptional regulator
K8Z42_00005	COG4626	Terminase
K8Z42_00015	COG0740	serine-type endopeptidase activity
K8Z42_00080	COG4824	toxin secretion phage lysis holin
K8Z42_00085	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_00085	COG1388	LysM domain
K8Z42_00085	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_00140	COG1683	Conserved Protein
K8Z42_00155	COG3708	Transcriptional regulator
K8Z42_00170	COG1252	NADH dehydrogenase
K8Z42_00185	COG3584	3D domain protein
K8Z42_00200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z42_00205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z42_00210	COG1268	BioY protein
K8Z42_00220	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z42_00245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z42_00250	COG5018	Exonuclease
K8Z42_00270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z42_00280	COG2267	carboxylic ester hydrolase activity
K8Z42_00285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z42_00290	COG1522	sequence-specific DNA binding
K8Z42_00295	COG0436	Aminotransferase
K8Z42_00300	COG1098	S1 RNA binding domain
K8Z42_00305	COG2155	Conserved Protein
K8Z42_00320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z42_00325	COG1285	pathogenesis
K8Z42_00360	COG0544	peptidyl-prolyl cis-trans isomerase activity
K8Z42_00480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z42_00490	COG0058	SHG alpha-glucan phosphorylase activity
K8Z42_00520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z42_00525	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z42_00530	COG1169	isochorismate synthase
K8Z42_00540	COG0596	Alpha beta hydrolase
K8Z42_00545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z42_00570	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z42_00590	COG3964	amidohydrolase
K8Z42_00610	COG2188	Transcriptional regulator
K8Z42_00640	COG0577	efflux transmembrane transporter activity
K8Z42_00645	COG1136	(ABC) transporter
K8Z42_00650	COG0577	efflux transmembrane transporter activity
K8Z42_00655	COG0577	efflux transmembrane transporter activity
K8Z42_00660	COG2205	protein histidine kinase activity
K8Z42_00665	COG0745	RESPONSE REGULATOR receiver
K8Z42_00670	COG0640	Transcriptional regulator
K8Z42_00675	COG5658	integral membrane protein
K8Z42_00685	COG2207	Transcriptional regulator
K8Z42_00685	COG3708	Transcriptional regulator
K8Z42_00690	COG1136	(ABC) transporter
K8Z42_00695	COG0577	efflux transmembrane transporter activity
K8Z42_00705	COG0586	Pfam SNARE associated Golgi protein
K8Z42_00730	COG1597	lipid kinase activity
K8Z42_00735	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z42_00760	COG0745	RESPONSE REGULATOR receiver
K8Z42_00765	COG5002	protein histidine kinase activity
K8Z42_00795	COG1842	Phage shock protein A
K8Z42_00815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_00830	COG1294	oxidase, subunit
K8Z42_00835	COG1271	oxidase subunit
K8Z42_00840	COG0288	reversible hydration of carbon dioxide
K8Z42_00850	COG1854	S-ribosylhomocysteine lyase activity
K8Z42_00880	COG0494	nUDIX hydrolase
K8Z42_00905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z42_00910	COG1116	anion transmembrane transporter activity
K8Z42_00915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z42_00940	COG1368	sulfuric ester hydrolase activity
K8Z42_00945	COG2267	carboxylic ester hydrolase activity
K8Z42_00950	COG3852	Histidine kinase
K8Z42_00955	COG5002	protein histidine kinase activity
K8Z42_00970	COG1349	DNA-binding transcription factor activity
K8Z42_01015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_01035	COG0438	transferase activity, transferring glycosyl groups
K8Z42_01040	COG0671	phosphoesterase, PA-phosphatase related
K8Z42_01045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z42_01050	COG2267	carboxylic ester hydrolase activity
K8Z42_01070	COG1794	racemase activity, acting on amino acids and derivatives
K8Z42_01075	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z42_01080	COG1242	4 iron, 4 sulfur cluster binding
K8Z42_01100	COG1136	(ABC) transporter
K8Z42_01110	COG0582	viral genome integration into host DNA
K8Z42_01115	COG0490	domain, Protein
K8Z42_01120	COG0475	glutathione-regulated potassium exporter activity
K8Z42_01125	COG2814	Major facilitator Superfamily
K8Z42_01170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z42_01180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z42_01200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z42_01205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z42_01215	COG0303	'Molybdopterin
K8Z42_01220	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z42_01225	COG0314	molybdopterin synthase activity
K8Z42_01250	COG1329	Transcriptional regulator
K8Z42_01270	COG3832	glyoxalase III activity
K8Z42_01280	COG2814	Major facilitator Superfamily
K8Z42_01285	COG2081	HI0933 family
K8Z42_01290	COG2244	polysaccharide biosynthetic process
K8Z42_01295	COG1187	pseudouridine synthase activity
K8Z42_01300	COG1349	DNA-binding transcription factor activity
K8Z42_01305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z42_01315	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z42_01320	COG0510	thiamine kinase activity
K8Z42_01335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_01345	COG1363	Peptidase, m42
K8Z42_01350	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z42_01355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z42_01365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z42_01380	COG1674	ftsk spoiiie
K8Z42_01395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_01410	COG2309	aminopeptidase activity
K8Z42_01420	COG3118	belongs to the thioredoxin family
K8Z42_01425	COG4851	CamS sex pheromone cAM373 precursor
K8Z42_01430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z42_01430	COG1605	Chorismate mutase
K8Z42_01435	COG1609	Transcriptional regulator
K8Z42_01470	COG3279	Response regulator of the LytR AlgR family
K8Z42_01490	COG0745	RESPONSE REGULATOR receiver
K8Z42_01490	COG2972	Histidine kinase
K8Z42_01495	COG0666	response to abiotic stimulus
K8Z42_01505	COG0745	RESPONSE REGULATOR receiver
K8Z42_01520	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z42_01525	COG0517	IMP dehydrogenase activity
K8Z42_01530	COG0454	-acetyltransferase
K8Z42_01535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z42_01540	COG0110	maltose O-acetyltransferase activity
K8Z42_01550	COG1595	DNA-templated transcription, initiation
K8Z42_01600	COG0626	cystathionine gamma-synthase activity
K8Z42_01605	COG1956	GAF domain-containing protein
K8Z42_01610	COG1309	transcriptional regulator
K8Z42_01615	COG0697	spore germination
K8Z42_01620	COG0583	DNA-binding transcription factor activity
K8Z42_01630	COG1104	cysteine desulfurase activity
K8Z42_01645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z42_01655	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z42_01670	COG3874	Sporulation protein YtfJ
K8Z42_01675	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z42_01680	COG0827	DNA restriction-modification system
K8Z42_01705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_01755	COG0589	response to stress
K8Z42_01760	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_01775	COG0662	Cupin 2, conserved barrel domain protein
K8Z42_01815	COG0006	proline dipeptidase activity
K8Z42_01830	COG4109	DRTGG domain
K8Z42_01845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z42_01860	COG0587	DNA-directed DNA polymerase activity
K8Z42_01865	COG0281	malic enzyme
K8Z42_01870	COG1725	Transcriptional regulator
K8Z42_01895	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z42_01900	COG0628	permease
K8Z42_01910	COG0372	Belongs to the citrate synthase family
K8Z42_01915	COG0538	isocitrate dehydrogenase activity
K8Z42_01935	COG0745	RESPONSE REGULATOR receiver
K8Z42_01940	COG5002	protein histidine kinase activity
K8Z42_01945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z42_01945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z42_01955	COG1971	Probably functions as a manganese efflux pump
K8Z42_01965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z42_01970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z42_01980	COG3611	Membrane attachment protein
K8Z42_01985	COG1484	DNA-dependent DNA replication
K8Z42_02000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z42_02025	COG1363	Peptidase, m42
K8Z42_02030	COG1309	transcriptional regulator
K8Z42_02035	COG1566	PFAM secretion protein HlyD family protein
K8Z42_02040	COG2814	Major facilitator Superfamily
K8Z42_02060	COG1418	mRNA catabolic process
K8Z42_02070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z42_02115	COG1286	toxin biosynthetic process
K8Z42_02120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z42_02120	COG1796	DNA polymerase
K8Z42_02130	COG1187	pseudouridine synthase activity
K8Z42_02135	COG1114	Component of the transport system for branched-chain amino acids
K8Z42_02140	COG5386	Cell surface protein
K8Z42_02150	COG5386	Cell surface protein
K8Z42_02165	COG1120	ATPase activity
K8Z42_02170	COG4509	Sortase family
K8Z42_02180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z42_02185	COG4895	conserved protein (DUF2196)
K8Z42_02195	COG0745	RESPONSE REGULATOR receiver
K8Z42_02200	COG2205	protein histidine kinase activity
K8Z42_02205	COG1131	(ABC) transporter
K8Z42_02235	COG2318	DinB family
K8Z42_02265	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_02270	COG1309	transcriptional regulator
K8Z42_02275	COG1024	Enoyl-CoA hydratase
K8Z42_02280	COG2086	electron transfer activity
K8Z42_02285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z42_02290	COG3118	belongs to the thioredoxin family
K8Z42_02300	COG1719	4-vinyl reductase, 4VR
K8Z42_02305	COG2009	succinate dehydrogenase
K8Z42_02310	COG1053	succinate dehydrogenase
K8Z42_02315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z42_02320	COG0824	Thioesterase
K8Z42_02325	COG1876	peptidase activity
K8Z42_02330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z42_02335	COG1360	Flagellar Motor Protein
K8Z42_02340	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z42_02345	COG4152	abc transporter atp-binding protein
K8Z42_02350	COG1668	transmembrane transport
K8Z42_02355	COG1959	2 iron, 2 sulfur cluster binding
K8Z42_02365	COG0697	spore germination
K8Z42_02370	COG1396	sequence-specific DNA binding
K8Z42_02375	COG1983	PspC domain protein
K8Z42_02380	COG0402	S-adenosylhomocysteine deaminase activity
K8Z42_02385	COG2233	PERMEase
K8Z42_02390	COG2197	response regulator
K8Z42_02410	COG5401	PFAM Sporulation and spore germination
K8Z42_02425	COG0622	Phosphoesterase
K8Z42_02470	COG1067	ATP-dependent peptidase activity
K8Z42_02470	COG0470	DNA polymerase III
K8Z42_02485	COG1764	response to oxidative stress
K8Z42_02490	COG1846	Transcriptional regulator
K8Z42_02500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z42_02510	COG1587	Uroporphyrinogen-III synthase
K8Z42_02515	COG0113	porphobilinogen synthase activity
K8Z42_02525	COG1388	LysM domain
K8Z42_02540	COG0285	dihydrofolate synthase activity
K8Z42_02560	COG1077	Cell shape determining protein MreB Mrl
K8Z42_02580	COG2894	cell division
K8Z42_02585	COG0739	heme binding
K8Z42_02590	COG1994	Peptidase M50
K8Z42_02595	COG1530	ribonuclease E activity
K8Z42_02605	COG2868	ribosomal protein
K8Z42_02615	COG3290	protein histidine kinase activity
K8Z42_02625	COG0745	RESPONSE REGULATOR receiver
K8Z42_02630	COG5002	protein histidine kinase activity
K8Z42_02635	COG1136	(ABC) transporter
K8Z42_02640	COG0577	efflux transmembrane transporter activity
K8Z42_02645	COG0577	efflux transmembrane transporter activity
K8Z42_02650	COG0077	Prephenate dehydratase
K8Z42_02655	COG2258	MOSC domain
K8Z42_02660	COG1827	regulation of RNA biosynthetic process
K8Z42_02665	COG1104	cysteine desulfurase activity
K8Z42_02670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z42_02675	COG0157	Belongs to the NadC ModD family
K8Z42_02705	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z42_02735	COG1862	Preprotein translocase
K8Z42_02745	COG2323	membrane
K8Z42_02750	COG2244	polysaccharide biosynthetic process
K8Z42_02760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z42_02760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z42_02765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z42_02770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z42_02770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z42_02780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z42_02805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z42_02815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z42_02820	COG1959	2 iron, 2 sulfur cluster binding
K8Z42_02825	COG1104	cysteine desulfurase activity
K8Z42_02840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z42_02860	COG0628	permease
K8Z42_02890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z42_02895	COG4122	O-methyltransferase activity
K8Z42_02900	COG0826	peptidase U32
K8Z42_02905	COG0826	peptidase U32
K8Z42_02925	COG0768	penicillin binding
K8Z42_02950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z42_02955	COG0626	cystathionine gamma-synthase activity
K8Z42_02960	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_02960	COG1454	alcohol dehydrogenase
K8Z42_02970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z42_03010	COG2259	Doxx family
K8Z42_03015	COG2514	catechol 2,3-dioxygenase activity
K8Z42_03025	COG3186	Phenylalanine-4-hydroxylase
K8Z42_03080	COG2267	carboxylic ester hydrolase activity
K8Z42_03090	COG1785	Belongs to the alkaline phosphatase family
K8Z42_03100	COG2357	RelA SpoT domain protein
K8Z42_03105	COG0778	Nitroreductase
K8Z42_03115	COG1595	DNA-templated transcription, initiation
K8Z42_03140	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z42_03145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z42_03155	COG1534	Rna-binding protein
K8Z42_03165	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z42_03170	COG0799	negative regulation of ribosome biogenesis
K8Z42_03175	COG2226	methyltransferase
K8Z42_03180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z42_03185	COG1555	photosystem II stabilization
K8Z42_03185	COG1596	polysaccharide export
K8Z42_03190	COG2131	deaminase
K8Z42_03195	COG2333	competence protein COMEC
K8Z42_03195	COG0658	competence protein
K8Z42_03205	COG1466	dna polymerase III delta subunit
K8Z42_03230	COG1733	regulation of RNA biosynthetic process
K8Z42_03235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z42_03265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z42_03270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z42_03275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z42_03280	COG1610	YqeY-like protein
K8Z42_03295	COG1702	phosphate starvation-inducible protein PhoH
K8Z42_03300	COG1480	7TM receptor with intracellular HD hydrolase
K8Z42_03310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z42_03315	COG0295	cytidine deaminase activity
K8Z42_03320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z42_03335	COG0517	IMP dehydrogenase activity
K8Z42_03350	COG0358	DNA primase activity
K8Z42_03355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z42_03365	COG2384	SAM-dependent methyltransferase
K8Z42_03370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z42_03400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_03405	COG1121	(ABC) transporter
K8Z42_03410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z42_03415	COG0735	belongs to the Fur family
K8Z42_03430	COG5521	maltodextrose utilization protein MalA
K8Z42_03440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z42_03445	COG0477	Major facilitator Superfamily
K8Z42_03450	COG0768	penicillin binding
K8Z42_03455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z42_03460	COG0573	inorganic phosphate transmembrane transporter activity
K8Z42_03465	COG0573	inorganic phosphate transmembrane transporter activity
K8Z42_03475	COG0704	Plays a role in the regulation of phosphate uptake
K8Z42_03480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z42_03485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z42_03490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z42_03495	COG4483	Protein conserved in bacteria
K8Z42_03500	COG1940	carbohydrate kinase activity
K8Z42_03510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_03530	COG0626	cystathionine gamma-synthase activity
K8Z42_03535	COG0626	cystathionine gamma-synthase activity
K8Z42_03540	COG0646	methionine synthase
K8Z42_03540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z42_03545	COG0646	methionine synthase
K8Z42_03545	COG1410	methionine synthase
K8Z42_03600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z42_03605	COG1459	type II secretion system
K8Z42_03670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z42_03700	COG1725	Transcriptional regulator
K8Z42_03705	COG1131	(ABC) transporter
K8Z42_03735	COG2076	Multidrug Resistance protein
K8Z42_03740	COG2076	Multidrug Resistance protein
K8Z42_03750	COG1609	Transcriptional regulator
K8Z42_03760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z42_03800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z42_03810	COG3872	metal-dependent enzyme
K8Z42_03825	COG0006	proline dipeptidase activity
K8Z42_03850	COG3854	ATPases associated with a variety of cellular activities
K8Z42_03895	COG0511	ligase activity, forming carbon-carbon bonds
K8Z42_03900	COG0439	Biotin carboxylase
K8Z42_03905	COG1302	Protein conserved in bacteria
K8Z42_03930	COG0142	geranyltranstransferase activity
K8Z42_03940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z42_03950	COG0497	DNA recombination
K8Z42_03955	COG0750	zinc metalloprotease
K8Z42_03970	COG3093	addiction module antidote protein HigA
K8Z42_03975	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z42_03985	COG3829	transcription factor binding
K8Z42_03985	COG3290	protein histidine kinase activity
K8Z42_03990	COG0280	phosphate acetyltransferase
K8Z42_04005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z42_04010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z42_04015	COG0022	dehydrogenase e1 component
K8Z42_04020	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z42_04025	COG0772	Belongs to the SEDS family
K8Z42_04030	COG2323	membrane
K8Z42_04050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z42_04055	COG0765	amino acid transport
K8Z42_04060	COG1126	abc transporter atp-binding protein
K8Z42_04065	COG4129	membrane
K8Z42_04070	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z42_04085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_04090	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z42_04100	COG1285	pathogenesis
K8Z42_04135	COG1760	l-serine dehydratase
K8Z42_04140	COG1760	l-serine dehydratase
K8Z42_04145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z42_04150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_04155	COG0300	oxidoreductase activity
K8Z42_04200	COG1522	sequence-specific DNA binding
K8Z42_04210	COG0737	Belongs to the 5'-nucleotidase family
K8Z42_04215	COG1757	Na H antiporter
K8Z42_04225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z42_04240	COG2226	methyltransferase
K8Z42_04240	COG1073	alpha beta
K8Z42_04270	COG0307	riboflavin synthase, alpha
K8Z42_04275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z42_04275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z42_04290	COG1073	alpha beta
K8Z42_04295	COG0456	acetyltransferase
K8Z42_04300	COG1609	Transcriptional regulator
K8Z42_04305	COG2056	Na+-H+ antiporter family
K8Z42_04310	COG0596	Alpha beta hydrolase
K8Z42_04320	COG0737	Belongs to the 5'-nucleotidase family
K8Z42_04320	COG1525	nuclease
K8Z42_04320	COG4085	toxin activity
K8Z42_04330	COG0456	acetyltransferase
K8Z42_04330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z42_04335	COG0656	L-ascorbic acid biosynthetic process
K8Z42_04340	COG0667	Aldo Keto reductase
K8Z42_04360	COG1300	Membrane
K8Z42_04365	COG0735	belongs to the Fur family
K8Z42_04375	COG4974	Belongs to the 'phage' integrase family
K8Z42_04400	COG0598	Magnesium transport protein CorA
K8Z42_04415	COG1846	Transcriptional regulator
K8Z42_04430	COG1131	(ABC) transporter
K8Z42_04435	COG1725	Transcriptional regulator
K8Z42_04440	COG1686	Belongs to the peptidase S11 family
K8Z42_04485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z42_04500	COG0697	spore germination
K8Z42_04505	COG0561	phosphatase activity
K8Z42_04510	COG4086	secreted protein
K8Z42_04515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z42_04520	COG0456	acetyltransferase
K8Z42_04525	COG1547	Domain of unknown function (DUF309)
K8Z42_04550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z42_04560	COG2188	Transcriptional regulator
K8Z42_04570	COG3711	transcriptional antiterminator
K8Z42_04575	COG1263	PTS System
K8Z42_04575	COG2190	(PTS) system
K8Z42_04575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z42_04600	COG0778	Nitroreductase
K8Z42_04605	COG2199	diguanylate cyclase activity
K8Z42_04615	COG2084	Dehydrogenase
K8Z42_04650	COG0436	Aminotransferase
K8Z42_04655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z42_04685	COG0640	Transcriptional regulator
K8Z42_04690	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_04715	COG4974	Belongs to the 'phage' integrase family
K8Z42_04735	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_04740	COG1695	Transcriptional regulator
K8Z42_04770	COG0183	Belongs to the thiolase family
K8Z42_04805	COG3842	ATPase activity
K8Z42_04810	COG0366	Alpha amylase catalytic
K8Z42_04820	COG2182	Extracellular solute-binding protein
K8Z42_04825	COG1175	transmembrane transport
K8Z42_04830	COG3833	ABC-type maltose transport systems, permease component
K8Z42_04835	COG1609	Transcriptional regulator
K8Z42_04840	COG0436	Aminotransferase
K8Z42_04850	COG2205	protein histidine kinase activity
K8Z42_04860	COG3209	COG3209 Rhs family protein
K8Z42_04880	COG2814	Major facilitator Superfamily
K8Z42_04925	COG1408	metallophosphoesterase
K8Z42_04930	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_04935	COG2200	EAL domain
K8Z42_04950	COG4703	Protein of unknown function (DUF1797)
K8Z42_04960	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z42_04970	COG0517	IMP dehydrogenase activity
K8Z42_04975	COG0583	DNA-binding transcription factor activity
K8Z42_04995	COG0569	domain protein
K8Z42_05000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z42_05010	COG0561	phosphatase activity
K8Z42_05025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z42_05030	COG0022	dehydrogenase e1 component
K8Z42_05075	COG1982	Orn Lys Arg decarboxylase major
K8Z42_05095	COG0483	inositol monophosphate 1-phosphatase activity
K8Z42_05105	COG1217	gtp-binding protein TYPA
K8Z42_05120	COG4896	Protein conserved in bacteria
K8Z42_05130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z42_05135	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z42_05145	COG0772	Belongs to the SEDS family
K8Z42_05150	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z42_05185	COG3336	cytochrome c oxidase
K8Z42_05200	COG2340	Cysteine-rich secretory protein family
K8Z42_05215	COG0406	alpha-ribazole phosphatase activity
K8Z42_05220	COG3679	Belongs to the UPF0342 family
K8Z42_05235	COG0742	ribosomal rna small subunit methyltransferase
K8Z42_05245	COG3314	Sporulation integral membrane protein YlbJ
K8Z42_05250	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z42_05255	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z42_05265	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z42_05270	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z42_05285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z42_05305	COG0768	penicillin binding
K8Z42_05310	COG0768	penicillin binding
K8Z42_05330	COG0772	Belongs to the SEDS family
K8Z42_05350	COG0849	cell division
K8Z42_05355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z42_05365	COG1191	sigma factor activity
K8Z42_05370	COG1191	sigma factor activity
K8Z42_05375	COG1873	PFAM PRC-barrel domain
K8Z42_05385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z42_05395	COG0762	integral membrane protein
K8Z42_05400	COG2302	S4 RNA-binding domain
K8Z42_05405	COG3599	regulation of cell shape
K8Z42_05425	COG0564	pseudouridine synthase activity
K8Z42_05485	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z42_05500	COG0006	proline dipeptidase activity
K8Z42_05510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z42_05515	COG1561	YicC-like family, N-terminal region
K8Z42_05535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z42_05540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z42_05555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z42_05555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z42_05565	COG0631	protein serine/threonine phosphatase activity
K8Z42_05570	COG0515	serine threonine protein kinase
K8Z42_05570	COG2815	serine threonine protein kinase
K8Z42_05580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z42_05585	COG1564	THIamine pyrophosphokinase
K8Z42_05600	COG1302	Protein conserved in bacteria
K8Z42_05605	COG1461	Dihydroxyacetone kinase
K8Z42_05610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z42_05625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z42_05630	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_05635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z42_05650	COG3344	reverse transcriptase
K8Z42_05660	COG0552	protein localization to endoplasmic reticulum
K8Z42_05670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z42_05680	COG1837	Belongs to the UPF0109 family
K8Z42_05720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z42_05725	COG0758	DNA mediated transformation
K8Z42_05730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z42_05740	COG4974	Belongs to the 'phage' integrase family
K8Z42_05785	COG4589	Belongs to the CDS family
K8Z42_05795	COG0750	zinc metalloprotease
K8Z42_05815	COG0195	Participates in both transcription termination and antitermination
K8Z42_05820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z42_05825	COG1358	cellular component organization or biogenesis
K8Z42_05835	COG1550	Protein conserved in bacteria
K8Z42_05840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z42_05850	COG0196	riboflavin kinase activity
K8Z42_05865	COG0726	polysaccharide deacetylase
K8Z42_05870	COG0612	Peptidase, M16
K8Z42_05875	COG1873	PFAM PRC-barrel domain
K8Z42_05880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z42_05885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z42_05890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z42_05895	COG0527	aspartate kinase activity
K8Z42_05905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z42_05910	COG0740	serine-type endopeptidase activity
K8Z42_05925	COG2188	Transcriptional regulator
K8Z42_05930	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z42_05935	COG3845	ABC transporter
K8Z42_05940	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z42_05945	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z42_05950	COG0612	Peptidase, M16
K8Z42_05955	COG0612	Peptidase, M16
K8Z42_05960	COG0300	oxidoreductase activity
K8Z42_05975	COG1426	Protein conserved in bacteria
K8Z42_05980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z42_06000	COG1692	metallophosphoesterase
K8Z42_06005	COG2359	stage V sporulation protein S
K8Z42_06015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z42_06015	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z42_06020	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z42_06030	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z42_06055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z42_06060	COG1368	sulfuric ester hydrolase activity
K8Z42_06070	COG3773	Cell wall hydrolase
K8Z42_06075	COG1404	Belongs to the peptidase S8 family
K8Z42_06080	COG0823	Involved in the tonB-independent uptake of proteins
K8Z42_06085	COG2723	6-phospho-beta-galactosidase activity
K8Z42_06090	COG2188	Transcriptional regulator
K8Z42_06100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_06110	COG1346	cytolysis
K8Z42_06130	COG1086	Polysaccharide biosynthesis protein
K8Z42_06150	COG5001	Diguanylate cyclase
K8Z42_06150	COG3300	MHYT domain
K8Z42_06155	COG2267	carboxylic ester hydrolase activity
K8Z42_06175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z42_06180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z42_06185	COG2169	Transcriptional regulator
K8Z42_06195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z42_06200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_06205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_06210	COG1120	ATPase activity
K8Z42_06215	COG2819	hydrolase of the alpha beta superfamily
K8Z42_06225	COG1937	Protein conserved in bacteria
K8Z42_06230	COG2608	mercury ion transmembrane transporter activity
K8Z42_06235	COG2217	Heavy metal translocating P-type atpase
K8Z42_06250	COG2116	formate transmembrane transporter activity
K8Z42_06255	COG1408	metallophosphoesterase
K8Z42_06265	COG1113	amino acid transport
K8Z42_06275	COG2322	membrane
K8Z42_06280	COG1979	alcohol dehydrogenase
K8Z42_06285	COG1349	DNA-binding transcription factor activity
K8Z42_06290	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z42_06295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z42_06295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z42_06295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z42_06300	COG1388	LysM domain
K8Z42_06300	COG3584	3D domain protein
K8Z42_06330	COG0464	growth
K8Z42_06340	COG2860	membrane
K8Z42_06345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z42_06350	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z42_06355	COG0789	Transcriptional regulator
K8Z42_06360	COG0174	glutamine synthetase
K8Z42_06370	COG1695	Transcriptional regulator
K8Z42_06390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z42_06415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z42_06450	COG1132	(ABC) transporter
K8Z42_06455	COG1132	(ABC) transporter
K8Z42_06480	COG0730	response to heat
K8Z42_06495	COG1346	cytolysis
K8Z42_06505	COG0583	DNA-binding transcription factor activity
K8Z42_06535	COG1473	amidohydrolase
K8Z42_06545	COG0785	Cytochrome C biogenesis protein
K8Z42_06550	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z42_06575	COG2226	methyltransferase
K8Z42_06600	COG0010	Belongs to the arginase family
K8Z42_06605	COG1329	Transcriptional regulator
K8Z42_06615	COG3344	reverse transcriptase
K8Z42_06625	COG0069	glutamate synthase activity
K8Z42_06640	COG0346	lactoylglutathione lyase activity
K8Z42_06645	COG0400	carboxylic ester hydrolase activity
K8Z42_06650	COG5002	protein histidine kinase activity
K8Z42_06660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_06700	COG0830	nickel cation binding
K8Z42_06720	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K8Z42_06750	COG1396	sequence-specific DNA binding
K8Z42_06755	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_06760	COG1268	BioY protein
K8Z42_06765	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_06770	COG0183	Belongs to the thiolase family
K8Z42_06785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z42_06795	COG2211	Major facilitator Superfamily
K8Z42_06825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z42_06830	COG1132	(ABC) transporter
K8Z42_06845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z42_06880	COG0824	Thioesterase
K8Z42_06885	COG4841	protein insertion into membrane
K8Z42_06895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K8Z42_06895	COG1328	CTP reductase activity
K8Z42_06905	COG0745	RESPONSE REGULATOR receiver
K8Z42_06910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z42_06915	COG1832	CoA-binding protein
K8Z42_06920	COG0187	DNA topoisomerase II activity
K8Z42_06925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z42_06930	COG0673	inositol 2-dehydrogenase activity
K8Z42_06950	COG1131	(ABC) transporter
K8Z42_06960	COG1595	DNA-templated transcription, initiation
K8Z42_06970	COG1316	TRANSCRIPTIONal
K8Z42_06975	COG4166	transmembrane transport
K8Z42_06980	COG4166	transmembrane transport
K8Z42_06985	COG4166	transmembrane transport
K8Z42_06990	COG2226	methyltransferase
K8Z42_07025	COG0531	amino acid
K8Z42_07040	COG0697	spore germination
K8Z42_07045	COG3383	formate dehydrogenase (NAD+) activity
K8Z42_07050	COG2427	Protein of unknown function (DUF1641)
K8Z42_07055	COG5609	conserved protein (DUF2294)
K8Z42_07060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z42_07070	COG2116	formate transmembrane transporter activity
K8Z42_07075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z42_07080	COG0303	'Molybdopterin
K8Z42_07085	COG0314	molybdopterin synthase activity
K8Z42_07095	COG0489	protein tyrosine kinase activity
K8Z42_07110	COG3326	Membrane
K8Z42_07115	COG2962	Rard protein
K8Z42_07120	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z42_07125	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z42_07135	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_07140	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_07150	COG4145	pantothenate transmembrane transporter activity
K8Z42_07165	COG0165	Argininosuccinate lyase
K8Z42_07175	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_07210	COG0716	FMN binding
K8Z42_07245	COG2720	vancomycin resistance protein
K8Z42_07250	COG2514	catechol 2,3-dioxygenase activity
K8Z42_07260	COG1285	pathogenesis
K8Z42_07270	COG3852	Histidine kinase
K8Z42_07295	COG0488	(ABC) transporter
K8Z42_07335	COG1404	Belongs to the peptidase S8 family
K8Z42_07370	COG0457	Tetratricopeptide repeat
K8Z42_07380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z42_07390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z42_07410	COG3344	reverse transcriptase
K8Z42_07440	COG0697	spore germination
K8Z42_07450	COG3397	chitin binding
K8Z42_07455	COG0823	Involved in the tonB-independent uptake of proteins
K8Z42_07465	COG1252	NADH dehydrogenase
K8Z42_07470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z42_07470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_07475	COG1183	phosphatidylcholine synthase activity
K8Z42_07500	COG0277	FAD linked oxidase domain protein
K8Z42_07505	COG0385	Bile acid
K8Z42_07515	COG0457	Tetratricopeptide repeat
K8Z42_07525	COG0604	alcohol dehydrogenase
K8Z42_07530	COG0640	Transcriptional regulator
K8Z42_07540	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z42_07565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z42_07595	COG1164	Oligoendopeptidase f
K8Z42_07600	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z42_07610	COG1193	negative regulation of DNA recombination
K8Z42_07625	COG2890	protein-(glutamine-N5) methyltransferase activity
K8Z42_07635	COG0583	DNA-binding transcription factor activity
K8Z42_07650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_07670	COG3739	integral membrane protein
K8Z42_07675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_07680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_07685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z42_07690	COG1247	-acetyltransferase
K8Z42_07700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z42_07705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z42_07735	COG2814	Major facilitator Superfamily
K8Z42_07740	COG1113	amino acid transport
K8Z42_07805	COG1151	hydroxylamine reductase activity
K8Z42_07860	COG1191	sigma factor activity
K8Z42_07885	COG1733	regulation of RNA biosynthetic process
K8Z42_07890	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z42_07895	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_07915	COG0384	phenazine biosynthesis protein PhzF
K8Z42_07935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_07955	COG0673	inositol 2-dehydrogenase activity
K8Z42_07960	COG2188	Transcriptional regulator
K8Z42_07990	COG0814	amino acid
K8Z42_08005	COG1733	regulation of RNA biosynthetic process
K8Z42_08010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z42_08010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z42_08015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z42_08015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z42_08025	COG0840	transmembrane signaling receptor activity
K8Z42_08055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z42_08060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z42_08065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z42_08070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z42_08080	COG1070	Carbohydrate kinase
K8Z42_08085	COG2706	6-phosphogluconolactonase activity
K8Z42_08090	COG3813	Protein conserved in bacteria
K8Z42_08095	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z42_08105	COG0697	spore germination
K8Z42_08135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z42_08145	COG0789	Transcriptional regulator
K8Z42_08150	COG1253	flavin adenine dinucleotide binding
K8Z42_08180	COG0477	Major facilitator Superfamily
K8Z42_08190	COG0500	methyltransferase
K8Z42_08215	COG0628	permease
K8Z42_08250	COG2365	Tyrosine phosphatase family
K8Z42_08260	COG1011	Hydrolase
K8Z42_08285	COG1131	(ABC) transporter
K8Z42_08295	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_08315	COG0469	pyruvate kinase activity
K8Z42_08325	COG0778	Nitroreductase
K8Z42_08330	COG1733	regulation of RNA biosynthetic process
K8Z42_08340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z42_08360	COG1288	antiporter activity
K8Z42_08415	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z42_08425	COG2031	fatty acid transporter
K8Z42_08440	COG2814	Major facilitator Superfamily
K8Z42_08445	COG1846	Transcriptional regulator
K8Z42_08460	COG0477	Major facilitator Superfamily
K8Z42_08470	COG2843	Capsule synthesis protein
K8Z42_08475	COG1876	peptidase activity
K8Z42_08500	COG5444	nuclease activity
K8Z42_08610	COG1396	sequence-specific DNA binding
K8Z42_08630	COG1309	transcriptional regulator
K8Z42_08635	COG0367	asparagine synthase
K8Z42_08660	COG1760	l-serine dehydratase
K8Z42_08665	COG1760	l-serine dehydratase
K8Z42_08670	COG0814	amino acid
K8Z42_08695	COG1533	DNA photolyase activity
K8Z42_08705	COG0076	glutamate decarboxylase activity
K8Z42_08715	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z42_08750	COG0772	Belongs to the SEDS family
K8Z42_08755	COG2239	Acts as a magnesium transporter
K8Z42_08765	COG0768	penicillin binding
K8Z42_08770	COG1595	DNA-templated transcription, initiation
K8Z42_08780	COG0768	penicillin binding
K8Z42_08785	COG0768	penicillin binding
K8Z42_08800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_08815	COG1131	(ABC) transporter
K8Z42_08825	COG1309	transcriptional regulator
K8Z42_08840	COG1960	acyl-CoA dehydrogenase activity
K8Z42_08845	COG0439	Biotin carboxylase
K8Z42_08850	COG0511	ligase activity, forming carbon-carbon bonds
K8Z42_08855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z42_08860	COG1024	Enoyl-CoA hydratase
K8Z42_08865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z42_08870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z42_08890	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_08905	COG0572	uridine kinase
K8Z42_08925	COG1686	Belongs to the peptidase S11 family
K8Z42_08955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z42_08970	COG3227	Zinc metalloprotease (Elastase)
K8Z42_08975	COG2207	Transcriptional regulator
K8Z42_09035	COG1942	4-Oxalocrotonate Tautomerase
K8Z42_09040	COG0583	DNA-binding transcription factor activity
K8Z42_09050	COG1131	(ABC) transporter
K8Z42_09080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_09085	COG2368	4-hydroxyphenylacetate
K8Z42_09105	COG3344	reverse transcriptase
K8Z42_09125	COG2323	membrane
K8Z42_09130	COG0693	protein deglycase activity
K8Z42_09140	COG3386	PFAM SMP-30 Gluconolaconase
K8Z42_09150	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z42_09155	COG3773	Cell wall hydrolase
K8Z42_09165	COG0745	RESPONSE REGULATOR receiver
K8Z42_09175	COG3344	reverse transcriptase
K8Z42_09185	COG0488	(ABC) transporter
K8Z42_09195	COG1136	(ABC) transporter
K8Z42_09200	COG0577	efflux transmembrane transporter activity
K8Z42_09220	COG0460	homoserine dehydrogenase
K8Z42_09225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_09235	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z42_09275	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_09300	COG2124	cytochrome p450
K8Z42_09335	COG0561	phosphatase activity
K8Z42_09340	COG5002	protein histidine kinase activity
K8Z42_09345	COG0768	penicillin binding
K8Z42_09355	COG1819	glycosyl
K8Z42_09360	COG1794	racemase activity, acting on amino acids and derivatives
K8Z42_09385	COG2205	protein histidine kinase activity
K8Z42_09390	COG0582	viral genome integration into host DNA
K8Z42_09435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z42_09450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z42_09460	COG0745	RESPONSE REGULATOR receiver
K8Z42_09465	COG5002	protein histidine kinase activity
K8Z42_09470	COG0604	alcohol dehydrogenase
K8Z42_09475	COG0671	phosphoesterase, PA-phosphatase related
K8Z42_09480	COG0768	penicillin binding
K8Z42_09525	COG2814	Major facilitator Superfamily
K8Z42_09530	COG2814	Major facilitator Superfamily
K8Z42_09550	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z42_09565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_09570	COG0697	spore germination
K8Z42_09605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z42_09615	COG2223	nitrite transmembrane transporter activity
K8Z42_09630	COG0592	DNA-directed DNA polymerase activity
K8Z42_09665	COG3878	Protein conserved in bacteria
K8Z42_09685	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z42_09725	COG0322	excinuclease ABC activity
K8Z42_09745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z42_09775	COG1011	Hydrolase
K8Z42_09780	COG0745	RESPONSE REGULATOR receiver
K8Z42_09785	COG5002	protein histidine kinase activity
K8Z42_09800	COG1136	(ABC) transporter
K8Z42_09805	COG0577	efflux transmembrane transporter activity
K8Z42_09810	COG1073	alpha beta
K8Z42_09815	COG0657	acetylesterase activity
K8Z42_09820	COG0076	glutamate decarboxylase activity
K8Z42_09835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z42_09865	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z42_09870	COG3227	Zinc metalloprotease (Elastase)
K8Z42_09875	COG0737	Belongs to the 5'-nucleotidase family
K8Z42_09890	COG0201	protein transport
K8Z42_09895	COG0697	spore germination
K8Z42_09900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_09935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_09950	COG2959	enzyme of heme biosynthesis
K8Z42_09990	COG1309	transcriptional regulator
K8Z42_10020	COG3284	Transcriptional regulator
K8Z42_10050	COG1959	2 iron, 2 sulfur cluster binding
K8Z42_10065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z42_10070	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z42_10075	COG0022	dehydrogenase e1 component
K8Z42_10080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z42_10090	COG2814	Major facilitator Superfamily
K8Z42_10105	COG3344	reverse transcriptase
K8Z42_10120	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_10125	COG0456	acetyltransferase
K8Z42_10125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z42_10165	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z42_10170	COG0517	IMP dehydrogenase activity
K8Z42_10170	COG4175	Glycine betaine
K8Z42_10200	COG2153	protein acetylation
K8Z42_10205	COG3397	chitin binding
K8Z42_10210	COG1819	glycosyl
K8Z42_10230	COG2205	protein histidine kinase activity
K8Z42_10235	COG2226	methyltransferase
K8Z42_10240	COG2315	Protein conserved in bacteria
K8Z42_10285	COG0456	acetyltransferase
K8Z42_10290	COG3973	AAA domain
K8Z42_10300	COG2105	PFAM AIG2 family protein
K8Z42_10305	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z42_10345	COG4637	Psort location Cytoplasmic, score
K8Z42_10360	COG3397	chitin binding
K8Z42_10375	COG1162	GTPase activity
K8Z42_10380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z42_10385	COG1115	amino acid carrier protein
K8Z42_10390	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_10395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z42_10405	COG3938	Belongs to the proline racemase family
K8Z42_10410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z42_10450	COG0586	Pfam SNARE associated Golgi protein
K8Z42_10460	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z42_10470	COG4166	transmembrane transport
K8Z42_10480	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z42_10495	COG0667	Aldo Keto reductase
K8Z42_10540	COG3850	Histidine kinase
K8Z42_10540	COG5002	protein histidine kinase activity
K8Z42_10545	COG0745	RESPONSE REGULATOR receiver
K8Z42_10565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z42_10575	COG1164	Oligoendopeptidase f
K8Z42_10580	COG1307	EDD domain protein, DegV family
K8Z42_10620	COG2814	Major facilitator Superfamily
K8Z42_10630	COG1664	Polymer-forming cytoskeletal
K8Z42_10635	COG0789	Transcriptional regulator
K8Z42_10640	COG4533	DNA binding
K8Z42_10645	COG0477	Major facilitator Superfamily
K8Z42_10645	COG2814	Major facilitator Superfamily
K8Z42_10670	COG2261	transglycosylase associated protein
K8Z42_10685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K8Z42_10720	COG0436	Aminotransferase
K8Z42_10725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z42_10735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8Z42_10750	COG1131	(ABC) transporter
K8Z42_10800	COG0628	permease
K8Z42_10815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z42_10820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z42_10825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z42_10855	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z42_10875	COG0697	spore germination
K8Z42_10900	COG4912	Dna alkylation repair
K8Z42_10905	COG0346	lactoylglutathione lyase activity
K8Z42_10910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_10920	COG0861	Integral membrane protein TerC family
K8Z42_10925	COG1368	sulfuric ester hydrolase activity
K8Z42_10930	COG0488	(ABC) transporter
K8Z42_10945	COG1033	growth of symbiont in host cell
K8Z42_10945	COG2409	Drug exporters of the RND superfamily
K8Z42_10950	COG1309	transcriptional regulator
K8Z42_10965	COG0287	Prephenate dehydrogenase
K8Z42_10980	COG1605	Chorismate mutase
K8Z42_10980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z42_11020	COG3584	3D domain protein
K8Z42_11020	COG1388	LysM domain
K8Z42_11035	COG0277	FAD linked oxidase domain protein
K8Z42_11050	COG1879	ABC-type sugar transport system periplasmic component
K8Z42_11060	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z42_11070	COG2390	Transcriptional regulator
K8Z42_11075	COG1070	Carbohydrate kinase
K8Z42_11100	COG2329	Antibiotic biosynthesis monooxygenase
K8Z42_11120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z42_11140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z42_11145	COG4187	Peptidase family M20/M25/M40
K8Z42_11150	COG1414	Transcriptional regulator
K8Z42_11155	COG0833	amino acid
K8Z42_11165	COG3239	Fatty acid desaturase
K8Z42_11175	COG2720	vancomycin resistance protein
K8Z42_11180	COG1785	Belongs to the alkaline phosphatase family
K8Z42_11190	COG3655	Transcriptional regulator
K8Z42_11210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_11215	COG0346	lactoylglutathione lyase activity
K8Z42_11245	COG0714	Associated with various cellular activities
K8Z42_11290	COG0463	Glycosyl transferase, family 2
K8Z42_11310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z42_11315	COG0753	catalase activity
K8Z42_11355	COG0714	Associated with various cellular activities
K8Z42_11440	COG0778	Nitroreductase
K8Z42_11445	COG1846	Transcriptional regulator
K8Z42_11465	COG3831	ATPase activity
K8Z42_11465	COG4884	unkown
K8Z42_11490	COG0590	tRNA wobble adenosine to inosine editing
K8Z42_11490	COG0037	tRNA processing
K8Z42_11500	COG0456	acetyltransferase
K8Z42_11515	COG0697	spore germination
K8Z42_11520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_11560	COG0730	response to heat
K8Z42_11570	COG0833	amino acid
K8Z42_11615	COG0768	penicillin binding
K8Z42_11650	COG1984	allophanate hydrolase subunit 2
K8Z42_11655	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z42_11660	COG1414	Transcriptional regulator
K8Z42_11670	COG3142	Participates in the control of copper homeostasis
K8Z42_11675	COG0640	Transcriptional regulator
K8Z42_11685	COG1960	acyl-CoA dehydrogenase activity
K8Z42_11700	COG3314	Sporulation integral membrane protein YlbJ
K8Z42_11710	COG0454	-acetyltransferase
K8Z42_11720	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z42_11745	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z42_11745	COG3848	Pyruvate phosphate dikinase
K8Z42_11765	COG1522	sequence-specific DNA binding
K8Z42_11770	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_11775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_11795	COG1063	alcohol dehydrogenase
K8Z42_11800	COG5002	protein histidine kinase activity
K8Z42_11825	COG2207	Transcriptional regulator
K8Z42_11845	COG0737	Belongs to the 5'-nucleotidase family
K8Z42_11850	COG2267	carboxylic ester hydrolase activity
K8Z42_11855	COG1335	isochorismatase
K8Z42_11875	COG0583	DNA-binding transcription factor activity
K8Z42_11885	COG2814	Major facilitator Superfamily
K8Z42_11920	COG0598	Magnesium transport protein CorA
K8Z42_11970	COG0415	Belongs to the DNA photolyase family
K8Z42_11995	COG0657	acetylesterase activity
K8Z42_12000	COG0288	reversible hydration of carbon dioxide
K8Z42_12010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z42_12015	COG5609	conserved protein (DUF2294)
K8Z42_12025	COG0456	acetyltransferase
K8Z42_12030	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z42_12040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_12050	COG0798	PFAM Bile acid sodium symporter
K8Z42_12055	COG0346	lactoylglutathione lyase activity
K8Z42_12060	COG0640	Transcriptional regulator
K8Z42_12065	COG2814	Major facilitator Superfamily
K8Z42_12070	COG1309	transcriptional regulator
K8Z42_12075	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_12080	COG1522	sequence-specific DNA binding
K8Z42_12095	COG0346	lactoylglutathione lyase activity
K8Z42_12180	COG2814	Major facilitator Superfamily
K8Z42_12195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z42_12205	COG1690	Belongs to the RtcB family
K8Z42_12215	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z42_12235	COG0577	efflux transmembrane transporter activity
K8Z42_12240	COG5002	protein histidine kinase activity
K8Z42_12240	COG3850	Histidine kinase
K8Z42_12250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_12280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z42_12310	COG3831	ATPase activity
K8Z42_12320	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_12320	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_12395	COG2239	Acts as a magnesium transporter
K8Z42_12400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_12410	COG0741	lytic transglycosylase activity
K8Z42_12480	COG2814	Major facilitator Superfamily
K8Z42_12495	COG1686	Belongs to the peptidase S11 family
K8Z42_12500	COG0110	maltose O-acetyltransferase activity
K8Z42_12505	COG0730	response to heat
K8Z42_12520	COG2002	toxin-antitoxin pair type II binding
K8Z42_12545	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z42_12575	COG1846	Transcriptional regulator
K8Z42_12580	COG3961	Belongs to the TPP enzyme family
K8Z42_12585	COG2226	methyltransferase
K8Z42_12595	COG0500	methyltransferase
K8Z42_12595	COG3615	Tellurite resistance protein tehB
K8Z42_12615	COG1309	transcriptional regulator
K8Z42_12635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_12655	COG1846	Transcriptional regulator
K8Z42_12675	COG2971	BadF BadG BcrA BcrD
K8Z42_12700	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z42_12725	COG1595	DNA-templated transcription, initiation
K8Z42_12730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z42_12770	COG1396	sequence-specific DNA binding
K8Z42_12805	COG1132	(ABC) transporter
K8Z42_12810	COG1132	(ABC) transporter
K8Z42_12825	COG2258	MOSC domain
K8Z42_12830	COG0583	DNA-binding transcription factor activity
K8Z42_12850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z42_12855	COG0583	DNA-binding transcription factor activity
K8Z42_12885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_12895	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z42_12920	COG1247	-acetyltransferase
K8Z42_12955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_12980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z42_13020	COG0028	Belongs to the TPP enzyme family
K8Z42_13035	COG1136	(ABC) transporter
K8Z42_13040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z42_13045	COG1187	pseudouridine synthase activity
K8Z42_13050	COG2329	Antibiotic biosynthesis monooxygenase
K8Z42_13065	COG1115	amino acid carrier protein
K8Z42_13075	COG2318	DinB family
K8Z42_13085	COG0776	regulation of translation
K8Z42_13100	COG2814	Major facilitator Superfamily
K8Z42_13105	COG3251	PFAM MbtH domain protein
K8Z42_13110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z42_13115	COG1535	isochorismatase
K8Z42_13115	COG3433	isochorismatase activity
K8Z42_13120	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z42_13125	COG1169	isochorismate synthase
K8Z42_13130	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_13135	COG2223	nitrite transmembrane transporter activity
K8Z42_13155	COG0419	ATPase involved in DNA repair
K8Z42_13160	COG0420	3'-5' exonuclease activity
K8Z42_13175	COG1024	Enoyl-CoA hydratase
K8Z42_13180	COG1280	lysine exporter protein (LysE YggA)
K8Z42_13190	COG2084	Dehydrogenase
K8Z42_13195	COG1960	acyl-CoA dehydrogenase activity
K8Z42_13200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z42_13205	COG2079	MmgE PrpD family protein
K8Z42_13210	COG0372	Belongs to the citrate synthase family
K8Z42_13215	COG4841	protein insertion into membrane
K8Z42_13220	COG2814	Major facilitator Superfamily
K8Z42_13230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z42_13230	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z42_13250	COG0300	oxidoreductase activity
K8Z42_13335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z42_13340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z42_13345	COG0671	phosphoesterase, PA-phosphatase related
K8Z42_13355	COG3064	Membrane
K8Z42_13355	COG4991	sh3 domain protein
K8Z42_13355	COG0515	serine threonine protein kinase
K8Z42_13390	COG1509	lysine 2,3-aminomutase activity
K8Z42_13395	COG3829	transcription factor binding
K8Z42_13400	COG0456	acetyltransferase
K8Z42_13405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z42_13410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z42_13415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z42_13420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z42_13435	COG5506	Protein of unknown function (DUF1694)
K8Z42_13440	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_13445	COG1253	flavin adenine dinucleotide binding
K8Z42_13480	COG1174	glycine betaine transport
K8Z42_13485	COG0517	IMP dehydrogenase activity
K8Z42_13485	COG1125	glycine betaine transport
K8Z42_13520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z42_13545	COG1064	alcohol dehydrogenase
K8Z42_13550	COG0384	phenazine biosynthesis protein PhzF
K8Z42_13555	COG1737	Transcriptional regulator
K8Z42_13560	COG2197	response regulator
K8Z42_13565	COG2203	Gaf domain
K8Z42_13565	COG4585	Histidine kinase
K8Z42_13570	COG0668	transmembrane transport
K8Z42_13585	COG1335	isochorismatase
K8Z42_13605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z42_13610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z42_13630	COG0367	asparagine synthase
K8Z42_13635	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z42_13640	COG1999	signal sequence binding
K8Z42_13650	COG1307	EDD domain protein, DegV family
K8Z42_13660	COG0805	protein transport
K8Z42_13670	COG1272	protein, Hemolysin III
K8Z42_13675	COG0204	Acyl-transferase
K8Z42_13685	COG0768	penicillin binding
K8Z42_13700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z42_13715	COG0546	phosphoglycolate phosphatase activity
K8Z42_13725	COG4473	ABC transporter
K8Z42_13730	COG1131	(ABC) transporter
K8Z42_13740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z42_13745	COG3655	Transcriptional regulator
K8Z42_13755	COG0456	acetyltransferase
K8Z42_13765	COG1794	racemase activity, acting on amino acids and derivatives
K8Z42_13775	COG2610	gluconate transmembrane transporter activity
K8Z42_13800	COG0733	neurotransmitter:sodium symporter activity
K8Z42_13805	COG0017	Asparaginyl-tRNA synthetase
K8Z42_13860	COG0018	arginyl-trna synthetase
K8Z42_13865	COG2136	Putative SAM-dependent methyltransferase
K8Z42_13865	COG2521	methyltransferase
K8Z42_13880	COG1413	lyase activity
K8Z42_13890	COG0629	single-stranded DNA binding
K8Z42_14000	COG0488	(ABC) transporter
K8Z42_14005	COG1418	mRNA catabolic process
K8Z42_14020	COG0457	Tetratricopeptide repeat
K8Z42_14070	COG2359	stage V sporulation protein S
K8Z42_14105	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z42_14110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z42_14115	COG2146	nitrite reductase [NAD(P)H] activity
K8Z42_14120	COG1587	Uroporphyrinogen-III synthase
K8Z42_14120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z42_14130	COG1648	precorrin-2 dehydrogenase activity
K8Z42_14140	COG2223	nitrite transmembrane transporter activity
K8Z42_14145	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K8Z42_14150	COG0314	molybdopterin synthase activity
K8Z42_14155	COG0303	'Molybdopterin
K8Z42_14160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z42_14165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z42_14170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z42_14175	COG2181	nitrate reductase activity
K8Z42_14180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z42_14185	COG1140	nitrate reductase beta subunit
K8Z42_14190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z42_14200	COG0714	Associated with various cellular activities
K8Z42_14205	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z42_14210	COG1305	Transglutaminase-like
K8Z42_14215	COG0386	Belongs to the glutathione peroxidase family
K8Z42_14230	COG0426	domain, Protein
K8Z42_14230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z42_14245	COG1595	DNA-templated transcription, initiation
K8Z42_14255	COG0604	alcohol dehydrogenase
K8Z42_14265	COG0346	lactoylglutathione lyase activity
K8Z42_14270	COG1082	Xylose isomerase domain protein TIM barrel
K8Z42_14290	COG2226	methyltransferase
K8Z42_14315	COG3874	Sporulation protein YtfJ
K8Z42_14415	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z42_14450	COG0456	acetyltransferase
K8Z42_14480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_14485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_14490	COG1819	glycosyl
K8Z42_14505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z42_14520	COG0561	phosphatase activity
K8Z42_14570	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_14605	COG3344	reverse transcriptase
K8Z42_14650	COG0740	serine-type endopeptidase activity
K8Z42_14775	COG3646	Phage regulatory protein
K8Z42_14825	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z42_14840	COG2211	Major facilitator Superfamily
K8Z42_14855	COG1876	peptidase activity
K8Z42_14865	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z42_14885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z42_14890	COG1114	Component of the transport system for branched-chain amino acids
K8Z42_14910	COG1253	flavin adenine dinucleotide binding
K8Z42_14915	COG2839	Protein conserved in bacteria
K8Z42_14920	COG0702	epimerase
K8Z42_14935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z42_14945	COG1607	acyl-coa hydrolase
K8Z42_14950	COG3689	TIGRFAM TIGR03943 family protein
K8Z42_14955	COG0701	Predicted permease
K8Z42_14965	COG2244	polysaccharide biosynthetic process
K8Z42_14970	COG0586	Pfam SNARE associated Golgi protein
K8Z42_14975	COG1051	belongs to the nudix hydrolase family
K8Z42_14980	COG5337	Spore coat protein CotH
K8Z42_15005	COG4166	transmembrane transport
K8Z42_15015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z42_15025	COG0702	epimerase
K8Z42_15035	COG3344	reverse transcriptase
K8Z42_15050	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z42_15055	COG0456	acetyltransferase
K8Z42_15060	COG0523	cobalamin synthesis protein
K8Z42_15070	COG4989	oxidoreductase activity
K8Z42_15075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_15080	COG1231	oxidoreductase activity
K8Z42_15090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z42_15110	COG0783	Belongs to the Dps family
K8Z42_15115	COG3949	Membrane
K8Z42_15130	COG0840	transmembrane signaling receptor activity
K8Z42_15155	COG3152	Membrane
K8Z42_15160	COG2814	Major facilitator Superfamily
K8Z42_15165	COG0667	Aldo Keto reductase
K8Z42_15170	COG0640	Transcriptional regulator
K8Z42_15175	COG1404	Belongs to the peptidase S8 family
K8Z42_15180	COG2002	toxin-antitoxin pair type II binding
K8Z42_15185	COG0577	efflux transmembrane transporter activity
K8Z42_15220	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z42_15230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_15235	COG1279	arginine transmembrane transporter activity
K8Z42_15240	COG2814	Major facilitator Superfamily
K8Z42_15250	COG1082	Xylose isomerase domain protein TIM barrel
K8Z42_15260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z42_15305	COG1247	-acetyltransferase
K8Z42_15310	COG1285	pathogenesis
K8Z42_15325	COG5002	protein histidine kinase activity
K8Z42_15330	COG0745	RESPONSE REGULATOR receiver
K8Z42_15340	COG1316	TRANSCRIPTIONal
K8Z42_15365	COG0460	homoserine dehydrogenase
K8Z42_15370	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_15400	COG0300	oxidoreductase activity
K8Z42_15405	COG5002	protein histidine kinase activity
K8Z42_15410	COG0745	RESPONSE REGULATOR receiver
K8Z42_15415	COG1132	(ABC) transporter
K8Z42_15425	COG0791	NLP P60 protein
K8Z42_15425	COG1388	LysM domain
K8Z42_15440	COG1686	Belongs to the peptidase S11 family
K8Z42_15480	COG1216	Glycosyl transferase, family 2
K8Z42_15490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z42_15495	COG4988	ABC transporter
K8Z42_15500	COG1294	oxidase, subunit
K8Z42_15505	COG1271	oxidase subunit
K8Z42_15520	COG1942	4-Oxalocrotonate Tautomerase
K8Z42_15530	COG0583	DNA-binding transcription factor activity
K8Z42_15550	COG0411	ABC transporter
K8Z42_15560	COG0523	cobalamin synthesis protein
K8Z42_15565	COG1231	oxidoreductase activity
K8Z42_15575	COG0628	permease
K8Z42_15585	COG0778	Nitroreductase
K8Z42_15590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z42_15595	COG1959	2 iron, 2 sulfur cluster binding
K8Z42_15600	COG0583	DNA-binding transcription factor activity
K8Z42_15605	COG0697	spore germination
K8Z42_15610	COG4549	nuclear export factor GLE1
K8Z42_15615	COG1276	copper resistance
K8Z42_15615	COG2372	response to copper ion
K8Z42_15625	COG1114	Component of the transport system for branched-chain amino acids
K8Z42_15645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z42_15655	COG2132	Multicopper oxidase
K8Z42_15665	COG0006	proline dipeptidase activity
K8Z42_15675	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z42_15690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z42_15695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z42_15705	COG2390	Transcriptional regulator
K8Z42_15710	COG1309	transcriptional regulator
K8Z42_15745	COG0531	amino acid
K8Z42_15750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z42_15765	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z42_15770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_15775	COG4166	transmembrane transport
K8Z42_15795	COG0427	acetyl-CoA hydrolase
K8Z42_15800	COG3279	Response regulator of the LytR AlgR family
K8Z42_15810	COG3384	dioxygenase
K8Z42_15815	COG2814	Major facilitator Superfamily
K8Z42_15840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z42_15860	COG0028	Belongs to the TPP enzyme family
K8Z42_15865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z42_15875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z42_15895	COG2323	membrane
K8Z42_15900	COG5566	PFAM Mor transcription activator
K8Z42_15905	COG0733	neurotransmitter:sodium symporter activity
K8Z42_15925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z42_15930	COG2223	nitrite transmembrane transporter activity
K8Z42_15935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z42_15945	COG0477	Major facilitator Superfamily
K8Z42_15955	COG1695	Transcriptional regulator
K8Z42_15970	COG2814	Major facilitator Superfamily
K8Z42_16005	COG3620	sequence-specific DNA binding
K8Z42_16025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z42_16030	COG0784	Response regulator, receiver
K8Z42_16035	COG4191	Histidine kinase
K8Z42_16040	COG0281	malic enzyme
K8Z42_16045	COG1027	Aspartate ammonia-lyase
K8Z42_16060	COG0528	UMP kinase activity
K8Z42_16065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z42_16085	COG1131	(ABC) transporter
K8Z42_16120	COG2733	membrane
K8Z42_16140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z42_16165	COG3340	Belongs to the peptidase S51 family
K8Z42_16170	COG0534	Mate efflux family protein
K8Z42_16200	COG0789	Transcriptional regulator
K8Z42_16205	COG1757	Na H antiporter
K8Z42_16220	COG0701	Predicted permease
K8Z42_16225	COG0523	cobalamin synthesis protein
K8Z42_16235	COG0697	spore germination
K8Z42_16240	COG1802	Transcriptional regulator
K8Z42_16270	COG0367	asparagine synthase
K8Z42_16295	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_16310	COG0406	alpha-ribazole phosphatase activity
K8Z42_16350	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z42_16355	COG3842	ATPase activity
K8Z42_16360	COG0583	DNA-binding transcription factor activity
K8Z42_16420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z42_16425	COG4786	Flagellar basal body rod
K8Z42_16430	COG1419	protein localization to endoplasmic reticulum
K8Z42_16435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z42_16440	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z42_16450	COG1987	bacterial-type flagellum assembly
K8Z42_16455	COG1338	Plays a role in the flagellum-specific transport system
K8Z42_16465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z42_16465	COG1776	CheC inhibitor of MCP methylation
K8Z42_16470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z42_16480	COG0741	lytic transglycosylase activity
K8Z42_16485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z42_16490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z42_16495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z42_16500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z42_16510	COG0835	chemotaxis
K8Z42_16510	COG0784	Response regulator, receiver
K8Z42_16545	COG1157	protein secretion by the type III secretion system
K8Z42_16555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z42_16560	COG1766	The M ring may be actively involved in energy transduction
K8Z42_16570	COG1558	bacterial-type flagellum-dependent cell motility
K8Z42_16575	COG1815	bacterial-type flagellum-dependent cell motility
K8Z42_16595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z42_16600	COG1256	bacterial-type flagellum assembly
K8Z42_16620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z42_16635	COG1776	CheC inhibitor of MCP methylation
K8Z42_16635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z42_16640	COG0643	Histidine kinase
K8Z42_16640	COG2198	Histidine kinase
K8Z42_16645	COG2201	protein-glutamate methylesterase activity
K8Z42_16650	COG1360	Flagellar Motor Protein
K8Z42_16655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z42_16665	COG1923	regulation of RNA biosynthetic process
K8Z42_16705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z42_16710	COG2323	membrane
K8Z42_16720	COG4978	Transcriptional regulator
K8Z42_16720	COG0789	Transcriptional regulator
K8Z42_16725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z42_16730	COG0475	glutathione-regulated potassium exporter activity
K8Z42_16740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z42_16745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z42_16765	COG1280	lysine exporter protein (LysE YggA)
K8Z42_16770	COG3403	YqcI/YcgG family
K8Z42_16805	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z42_16825	COG0454	-acetyltransferase
K8Z42_16840	COG0438	transferase activity, transferring glycosyl groups
K8Z42_16845	COG1215	transferase activity, transferring glycosyl groups
K8Z42_16860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z42_16870	COG3944	biosynthesis protein
K8Z42_16885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z42_16935	COG0456	acetyltransferase
K8Z42_16945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z42_16955	COG2311	Membrane
K8Z42_16960	COG2233	PERMEase
K8Z42_16970	COG0024	Methionine aminopeptidase
K8Z42_16980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z42_16985	COG1199	ATP-dependent helicase activity
K8Z42_16995	COG0116	Belongs to the methyltransferase superfamily
K8Z42_17050	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z42_17050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z42_17060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z42_17065	COG3935	DnaD domain protein
K8Z42_17085	COG1199	ATP-dependent helicase activity
K8Z42_17085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z42_17120	COG0438	transferase activity, transferring glycosyl groups
K8Z42_17140	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z42_17145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_17160	COG2738	Putative neutral zinc metallopeptidase
K8Z42_17175	COG4347	Protein of unknown function (DUF1405)
K8Z42_17180	COG2010	Cytochrome c
K8Z42_17180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z42_17185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z42_17205	COG0457	Tetratricopeptide repeat
K8Z42_17235	COG0142	geranyltranstransferase activity
K8Z42_17245	COG0142	geranyltranstransferase activity
K8Z42_17260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z42_17330	COG0252	asparaginase activity
K8Z42_17335	COG0492	ferredoxin-NADP+ reductase activity
K8Z42_17355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z42_17365	COG0789	Transcriptional regulator
K8Z42_17370	COG1408	metallophosphoesterase
K8Z42_17380	COG1266	CAAX protease self-immunity
K8Z42_17385	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z42_17395	COG1141	Ferredoxin
K8Z42_17400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z42_17415	COG2096	Adenosyltransferase
K8Z42_17420	COG5002	protein histidine kinase activity
K8Z42_17425	COG0745	RESPONSE REGULATOR receiver
K8Z42_17430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z42_17435	COG1333	cytochrome c biogenesis protein
K8Z42_17445	COG1187	pseudouridine synthase activity
K8Z42_17450	COG0700	Nucleoside recognition
K8Z42_17455	COG2715	membrane protein required for spore maturation
K8Z42_17460	COG1686	Belongs to the peptidase S11 family
K8Z42_17465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z42_17480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z42_17480	COG0392	lysyltransferase activity
K8Z42_17495	COG5002	protein histidine kinase activity
K8Z42_17500	COG0582	viral genome integration into host DNA
K8Z42_17510	COG1801	Protein of unknown function DUF72
K8Z42_17515	COG3852	Histidine kinase
K8Z42_17530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z42_17535	COG1392	Phosphate transport regulator
K8Z42_17540	COG0306	phosphate transporter
K8Z42_17545	COG0730	response to heat
K8Z42_17595	COG1114	Component of the transport system for branched-chain amino acids
K8Z42_17605	COG2197	response regulator
K8Z42_17610	COG4585	Histidine kinase
K8Z42_17615	COG4758	membrane
K8Z42_17630	COG1757	Na H antiporter
K8Z42_17655	COG0733	neurotransmitter:sodium symporter activity
K8Z42_17660	COG1648	precorrin-2 dehydrogenase activity
K8Z42_17680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z42_17685	COG0529	Catalyzes the synthesis of activated sulfate
K8Z42_17705	COG0019	diaminopimelate decarboxylase activity
K8Z42_17715	COG1368	sulfuric ester hydrolase activity
K8Z42_17720	COG1183	phosphatidylcholine synthase activity
K8Z42_17735	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z42_17810	COG0440	acetolactate synthase activity
K8Z42_17815	COG0028	Belongs to the TPP enzyme family
K8Z42_17820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z42_17840	COG3874	Sporulation protein YtfJ
K8Z42_17845	COG4709	membrane
K8Z42_17850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z42_17855	COG1301	dicarboxylic acid transport
K8Z42_17865	COG1846	Transcriptional regulator
K8Z42_17915	COG0716	FMN binding
K8Z42_17940	COG1696	Membrane protein involved in D-alanine export
K8Z42_17950	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z42_17955	COG2070	2-Nitropropane dioxygenase
K8Z42_17960	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z42_17970	COG1335	isochorismatase
K8Z42_17980	COG1522	sequence-specific DNA binding
K8Z42_18000	COG1131	(ABC) transporter
K8Z42_18010	COG1131	(ABC) transporter
K8Z42_18015	COG1725	Transcriptional regulator
K8Z42_18020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z42_18030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z42_18035	COG1780	Probably involved in ribonucleotide reductase function
K8Z42_18060	COG4873	Protein conserved in bacteria
K8Z42_18075	COG0720	synthase
K8Z42_18085	COG5002	protein histidine kinase activity
K8Z42_18095	COG2318	DinB family
K8Z42_18105	COG1846	Transcriptional regulator
K8Z42_18110	COG3852	Histidine kinase
K8Z42_18120	COG2861	carbohydrate metabolic process
K8Z42_18130	COG0235	Class ii aldolase
K8Z42_18140	COG1349	DNA-binding transcription factor activity
K8Z42_18165	COG3842	ATPase activity
K8Z42_18170	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z42_18185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z42_18195	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z42_18200	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_18220	COG2030	dehydratase
K8Z42_18230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z42_18235	COG0861	Integral membrane protein TerC family
K8Z42_18240	COG2116	formate transmembrane transporter activity
K8Z42_18250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z42_18270	COG2186	Transcriptional regulator
K8Z42_18275	COG5002	protein histidine kinase activity
K8Z42_18280	COG0745	RESPONSE REGULATOR receiver
K8Z42_18290	COG3835	regulator
K8Z42_18295	COG0277	FAD linked oxidase domain protein
K8Z42_18300	COG0247	lactate metabolic process
K8Z42_18305	COG2340	Cysteine-rich secretory protein family
K8Z42_18315	COG0564	pseudouridine synthase activity
K8Z42_18325	COG2409	Drug exporters of the RND superfamily
K8Z42_18340	COG1177	transmembrane transport
K8Z42_18345	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z42_18355	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_18390	COG0681	Belongs to the peptidase S26 family
K8Z42_18395	COG1686	Belongs to the peptidase S11 family
K8Z42_18405	COG2226	methyltransferase
K8Z42_18425	COG1668	transmembrane transport
K8Z42_18430	COG4152	abc transporter atp-binding protein
K8Z42_18470	COG1476	TRANSCRIPTIONal
K8Z42_18480	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z42_18500	COG2226	methyltransferase
K8Z42_18545	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z42_18550	COG1620	l-lactate permease
K8Z42_18585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z42_18585	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z42_18595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z42_18620	COG2382	esterase
K8Z42_18630	COG2153	protein acetylation
K8Z42_18675	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z42_18690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z42_18710	COG0457	Tetratricopeptide repeat
K8Z42_18710	COG0463	Glycosyl transferase, family 2
K8Z42_18730	COG1216	Glycosyl transferase, family 2
K8Z42_18735	COG0772	Belongs to the SEDS family
K8Z42_18750	COG0564	pseudouridine synthase activity
K8Z42_18760	COG2357	RelA SpoT domain protein
K8Z42_18770	COG4116	CYTH
K8Z42_18775	COG2346	COG2346, Truncated hemoglobins
K8Z42_18790	COG1164	Oligoendopeptidase f
K8Z42_18800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z42_18810	COG0861	Integral membrane protein TerC family
K8Z42_18825	COG4166	transmembrane transport
K8Z42_18830	COG0534	Mate efflux family protein
K8Z42_18835	COG4608	Belongs to the ABC transporter superfamily
K8Z42_18840	COG0444	Belongs to the ABC transporter superfamily
K8Z42_18845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z42_18850	COG0601	transmembrane transport
K8Z42_18855	COG4166	transmembrane transport
K8Z42_18865	COG0180	Tryptophanyl-tRNA synthetase
K8Z42_18875	COG5504	Zn-dependent protease
K8Z42_18880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z42_18885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z42_18900	COG2267	carboxylic ester hydrolase activity
K8Z42_18920	COG0561	phosphatase activity
K8Z42_18935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_18960	COG2996	Protein conserved in bacteria
K8Z42_18980	COG0004	ammonium transporteR
K8Z42_18985	COG3339	Conserved Protein
K8Z42_19010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z42_19020	COG0753	catalase activity
K8Z42_19050	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_19050	COG1388	LysM domain
K8Z42_19050	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_19055	COG4824	toxin secretion phage lysis holin
K8Z42_19125	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_19160	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_19185	COG3331	DNA recombination
K8Z42_19285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z42_19300	COG0367	asparagine synthase
K8Z42_19325	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z42_19385	COG0398	Pfam SNARE associated Golgi protein
K8Z42_19405	COG1278	Cold shock
K8Z42_19420	COG2224	Isocitrate lyase
K8Z42_19425	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z42_19435	COG3693	PFAM glycoside hydrolase, family 10
K8Z42_19440	COG0840	transmembrane signaling receptor activity
K8Z42_19445	COG0501	Belongs to the peptidase M48B family
K8Z42_19465	COG0745	RESPONSE REGULATOR receiver
K8Z42_19480	COG2207	Transcriptional regulator
K8Z42_19480	COG3708	Transcriptional regulator
K8Z42_19485	COG1595	DNA-templated transcription, initiation
K8Z42_19495	COG1078	dGTPase activity
K8Z42_19500	COG1408	metallophosphoesterase
K8Z42_19505	COG1073	alpha beta
K8Z42_19600	COG4208	sulfate ABC transporter
K8Z42_19610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K8Z42_19620	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_19635	COG0095	Lipoate-protein ligase
K8Z42_19640	COG1234	tRNA 3'-trailer cleavage
K8Z42_19650	COG1609	Transcriptional regulator
K8Z42_19655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_19685	COG1511	domain protein
K8Z42_19685	COG1511	domain protein
K8Z42_19690	COG1309	transcriptional regulator
K8Z42_19725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z42_19740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z42_19745	COG2329	Antibiotic biosynthesis monooxygenase
K8Z42_19750	COG3428	Bacterial PH domain
K8Z42_19755	COG3402	PFAM membrane-flanked domain
K8Z42_19760	COG0697	spore germination
K8Z42_19795	COG3428	Bacterial PH domain
K8Z42_19800	COG3402	PFAM membrane-flanked domain
K8Z42_19810	COG1309	transcriptional regulator
K8Z42_19825	COG4473	ABC transporter
K8Z42_19830	COG1131	(ABC) transporter
K8Z42_19835	COG0537	adenosine 5'-monophosphoramidase activity
K8Z42_19840	COG4980	gas vesicle protein
K8Z42_19865	COG3973	AAA domain
K8Z42_19870	COG0772	Belongs to the SEDS family
K8Z42_19880	COG1595	DNA-templated transcription, initiation
K8Z42_19895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z42_19905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z42_19910	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z42_19915	COG3620	sequence-specific DNA binding
K8Z42_19920	COG2140	Oxalate decarboxylase
K8Z42_19950	COG0457	Tetratricopeptide repeat
K8Z42_19955	COG0346	lactoylglutathione lyase activity
K8Z42_19960	COG0346	lactoylglutathione lyase activity
K8Z42_19985	COG4717	serine-type aminopeptidase activity
K8Z42_19990	COG0420	3'-5' exonuclease activity
K8Z42_20010	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z42_20020	COG2186	Transcriptional regulator
K8Z42_20065	COG5002	protein histidine kinase activity
K8Z42_20065	COG0784	Response regulator, receiver
K8Z42_20065	COG2205	protein histidine kinase activity
K8Z42_20070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z42_20075	COG2208	phosphoserine phosphatase activity
K8Z42_20085	COG1191	sigma factor activity
K8Z42_20160	COG2373	Large extracellular alpha-helical protein
K8Z42_20200	COG2376	Dihydroxyacetone kinase
K8Z42_20210	COG2376	Dihydroxyacetone kinase
K8Z42_20235	COG0640	Transcriptional regulator
K8Z42_20240	COG2814	Major facilitator Superfamily
K8Z42_20260	COG1183	phosphatidylcholine synthase activity
K8Z42_20315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z42_20330	COG1522	sequence-specific DNA binding
K8Z42_20335	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z42_20370	COG1073	alpha beta
K8Z42_20390	COG3344	reverse transcriptase
K8Z42_20410	COG2020	methyltransferase activity
K8Z42_20465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_20485	COG0477	Major facilitator Superfamily
K8Z42_20495	COG1842	Phage shock protein A
K8Z42_20505	COG1288	antiporter activity
K8Z42_20510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K8Z42_20535	COG0305	Participates in initiation and elongation during chromosome replication
K8Z42_20550	COG0305	Participates in initiation and elongation during chromosome replication
K8Z42_20565	COG0494	nUDIX hydrolase
K8Z42_20570	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z42_20575	COG4565	transcriptional regulatory protein
K8Z42_20580	COG3290	protein histidine kinase activity
K8Z42_20585	COG0477	Major facilitator Superfamily
K8Z42_20685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_20700	COG0322	excinuclease ABC activity
K8Z42_20705	COG4608	Belongs to the ABC transporter superfamily
K8Z42_20710	COG0444	Belongs to the ABC transporter superfamily
K8Z42_20715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z42_20720	COG0601	transmembrane transport
K8Z42_20760	COG1363	Peptidase, m42
K8Z42_20780	COG1024	Enoyl-CoA hydratase
K8Z42_20800	COG2244	polysaccharide biosynthetic process
K8Z42_20805	COG0659	secondary active sulfate transmembrane transporter activity
K8Z42_20820	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_20825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z42_20830	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_20830	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_20840	COG0561	phosphatase activity
K8Z42_20855	COG3527	Alpha-acetolactate decarboxylase
K8Z42_20860	COG0028	Belongs to the TPP enzyme family
K8Z42_20890	COG0189	ligase activity
K8Z42_20905	COG1126	abc transporter atp-binding protein
K8Z42_20910	COG0765	amino acid transport
K8Z42_20915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z42_20920	COG1132	(ABC) transporter
K8Z42_20925	COG1132	(ABC) transporter
K8Z42_20930	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_20945	COG0531	amino acid
K8Z42_20955	COG0753	catalase activity
K8Z42_20960	COG0693	protein deglycase activity
K8Z42_20975	COG2211	Major facilitator Superfamily
K8Z42_20980	COG4533	DNA binding
K8Z42_20995	COG1733	regulation of RNA biosynthetic process
K8Z42_21000	COG2814	Major facilitator Superfamily
K8Z42_21005	COG1309	transcriptional regulator
K8Z42_21025	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_21030	COG0165	Argininosuccinate lyase
K8Z42_21030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K8Z42_21035	COG1522	sequence-specific DNA binding
K8Z42_21055	COG2259	Doxx family
K8Z42_21065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z42_21065	COG1263	PTS System
K8Z42_21075	COG1737	Transcriptional regulator
K8Z42_21085	COG0475	glutathione-regulated potassium exporter activity
K8Z42_21090	COG0531	amino acid
K8Z42_21125	COG0586	Pfam SNARE associated Golgi protein
K8Z42_21160	COG3546	catalase activity
K8Z42_21165	COG1114	Component of the transport system for branched-chain amino acids
K8Z42_21180	COG5522	Integral membrane protein (intg_mem_TP0381)
K8Z42_21190	COG1136	(ABC) transporter
K8Z42_21195	COG0577	efflux transmembrane transporter activity
K8Z42_21200	COG3584	3D domain protein
K8Z42_21200	COG1388	LysM domain
K8Z42_21225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z42_21230	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z42_21235	COG3711	transcriptional antiterminator
K8Z42_21235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z42_21250	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8Z42_21255	COG0604	alcohol dehydrogenase
K8Z42_21260	COG1316	TRANSCRIPTIONal
K8Z42_21270	COG0730	response to heat
K8Z42_21275	COG2210	Belongs to the sulfur carrier protein TusA family
K8Z42_21290	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z42_21295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z42_21295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_21300	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z42_21300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z42_21305	COG1937	Protein conserved in bacteria
K8Z42_21310	COG0446	pyridine nucleotide-disulphide oxidoreductase
K8Z42_21320	COG3591	Belongs to the peptidase S1B family
K8Z42_21330	COG2719	SpoVR family
K8Z42_21335	COG0778	Nitroreductase
K8Z42_21400	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_21405	COG2252	PERMEase
K8Z42_21415	COG1136	(ABC) transporter
K8Z42_21440	COG1846	Transcriptional regulator
K8Z42_21445	COG2814	Major facilitator Superfamily
K8Z42_21450	COG2205	protein histidine kinase activity
K8Z42_21490	COG0351	phosphomethylpyrimidine kinase
K8Z42_21495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z42_21505	COG2104	thiamine diphosphate biosynthetic process
K8Z42_21510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z42_21515	COG0352	thiamine-phosphate diphosphorylase activity
K8Z42_21520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z42_21525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z42_21530	COG1116	anion transmembrane transporter activity
K8Z42_21535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z42_21555	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z42_21675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z42_21680	COG0581	inorganic phosphate transmembrane transporter activity
K8Z42_21685	COG0573	inorganic phosphate transmembrane transporter activity
K8Z42_21690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z42_21695	COG1918	ferrous iron import across plasma membrane
K8Z42_21695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z42_21700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z42_21705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z42_21720	COG0531	amino acid
K8Z42_21725	COG0697	spore germination
K8Z42_21730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z42_21745	COG4990	cell redox homeostasis
K8Z42_21750	COG0833	amino acid
K8Z42_21760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z42_21765	COG1845	cytochrome c oxidase, subunit III
K8Z42_21775	COG0475	glutathione-regulated potassium exporter activity
K8Z42_21775	COG0569	domain protein
K8Z42_21785	COG2153	protein acetylation
K8Z42_21800	COG2252	PERMEase
K8Z42_21805	COG1113	amino acid transport
K8Z42_21820	COG1114	Component of the transport system for branched-chain amino acids
K8Z42_21825	COG3104	oligopeptide transport
K8Z42_21845	COG1476	TRANSCRIPTIONal
K8Z42_21850	COG3583	domain protein
K8Z42_21850	COG3584	3D domain protein
K8Z42_21855	COG0840	transmembrane signaling receptor activity
K8Z42_21900	COG1674	ftsk spoiiie
K8Z42_22000	COG0740	serine-type endopeptidase activity
K8Z42_22010	COG1802	Transcriptional regulator
K8Z42_22010	COG4626	Terminase
K8Z42_22060	COG0582	viral genome integration into host DNA
K8Z42_22150	COG1396	sequence-specific DNA binding
K8Z42_22185	COG1063	alcohol dehydrogenase
K8Z42_22215	COG1879	ABC-type sugar transport system periplasmic component
K8Z42_22220	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z42_22235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z42_22240	COG1609	Transcriptional regulator
K8Z42_22245	COG0477	Major facilitator Superfamily
K8Z42_22250	COG1846	Transcriptional regulator
K8Z42_22255	COG2271	Major facilitator Superfamily
K8Z42_22285	COG5002	protein histidine kinase activity
K8Z42_22290	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z42_22295	COG2378	regulation of single-species biofilm formation
K8Z42_22305	COG1595	DNA-templated transcription, initiation
K8Z42_22320	COG0833	amino acid
K8Z42_22325	COG0765	amino acid transport
K8Z42_22330	COG0765	amino acid transport
K8Z42_22335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z42_22340	COG1126	abc transporter atp-binding protein
K8Z42_22345	COG1115	amino acid carrier protein
K8Z42_22350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z42_22355	COG0697	spore germination
K8Z42_22370	COG0366	Alpha amylase catalytic
K8Z42_22375	COG1263	PTS System
K8Z42_22375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z42_22380	COG2188	Transcriptional regulator
K8Z42_22385	COG0531	amino acid
K8Z42_22405	COG0714	Associated with various cellular activities
K8Z42_22410	COG4548	von Willebrand factor, type A
K8Z42_22420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z42_22430	COG2226	methyltransferase
K8Z42_22440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_22445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_22450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z42_22455	COG3104	oligopeptide transport
K8Z42_22480	COG1620	l-lactate permease
K8Z42_22485	COG1027	Aspartate ammonia-lyase
K8Z42_22490	COG1253	flavin adenine dinucleotide binding
K8Z42_22495	COG0346	lactoylglutathione lyase activity
K8Z42_22505	COG3344	reverse transcriptase
K8Z42_22515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z42_22520	COG1316	TRANSCRIPTIONal
K8Z42_22525	COG2720	vancomycin resistance protein
K8Z42_22545	COG3227	Zinc metalloprotease (Elastase)
K8Z42_22560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z42_22565	COG2217	Heavy metal translocating P-type atpase
K8Z42_22570	COG0640	Transcriptional regulator
K8Z42_22580	COG0531	amino acid
K8Z42_22595	COG2427	Protein of unknown function (DUF1641)
K8Z42_22600	COG3383	formate dehydrogenase (NAD+) activity
K8Z42_22605	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z42_22610	COG0456	acetyltransferase
K8Z42_22610	COG0454	-acetyltransferase
K8Z42_22615	COG0745	RESPONSE REGULATOR receiver
K8Z42_22620	COG5002	protein histidine kinase activity
K8Z42_22630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_22635	COG0697	spore germination
K8Z42_22645	COG0281	malic enzyme
K8Z42_22650	COG3493	citrate carrier protein
K8Z42_22655	COG4565	transcriptional regulatory protein
K8Z42_22660	COG3290	protein histidine kinase activity
K8Z42_22670	COG4990	cell redox homeostasis
K8Z42_22680	COG3850	Histidine kinase
K8Z42_22680	COG5002	protein histidine kinase activity
K8Z42_22685	COG0745	RESPONSE REGULATOR receiver
K8Z42_22690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z42_22700	COG0395	ABC-type sugar transport system, permease component
K8Z42_22705	COG1175	transmembrane transport
K8Z42_22710	COG3842	ATPase activity
K8Z42_22715	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z42_22740	COG2851	Citrate transporter
K8Z42_22745	COG4565	transcriptional regulatory protein
K8Z42_22750	COG3290	protein histidine kinase activity
K8Z42_22760	COG2268	Band 7 protein
K8Z42_22765	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z42_22775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z42_22795	COG2766	serine protein kinase
K8Z42_22800	COG1716	ATPase activity
K8Z42_22800	COG5001	Diguanylate cyclase
K8Z42_22805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z42_22830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z42_22950	COG0735	belongs to the Fur family
K8Z42_22955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z42_22975	COG4555	ABC transporter
K8Z42_22985	COG0067	glutamate synthase
K8Z42_22985	COG0069	glutamate synthase activity
K8Z42_22985	COG0070	glutamate synthase
K8Z42_22990	COG4129	membrane
K8Z42_22995	COG1132	(ABC) transporter
K8Z42_23020	COG1194	a g-specific adenine glycosylase
K8Z42_23025	COG1988	membrane-bound metal-dependent
K8Z42_23055	COG1090	epimerase
K8Z42_23060	COG1228	amidohydrolase
K8Z42_23080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z42_23100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z42_23100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z42_23110	COG0463	Glycosyl transferase, family 2
K8Z42_23125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z42_23130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z42_23130	COG1263	PTS System
K8Z42_23160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z42_23165	COG0833	amino acid
K8Z42_23175	COG3829	transcription factor binding
K8Z42_23190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z42_23195	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z42_23215	COG0535	radical SAM domain protein
K8Z42_23225	COG0387	Pfam Sodium calcium exchanger
K8Z42_23230	COG3871	stress protein (general stress protein 26)
K8Z42_23245	COG0586	Pfam SNARE associated Golgi protein
K8Z42_23270	COG2217	Heavy metal translocating P-type atpase
K8Z42_23275	COG1295	ribonuclease BN
K8Z42_23285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z42_23300	COG3853	Toxic anion resistance protein (TelA)
K8Z42_23310	COG0861	Integral membrane protein TerC family
K8Z42_23315	COG2310	stress, protein
K8Z42_23320	COG2310	stress, protein
K8Z42_23325	COG2310	stress, protein
K8Z42_23355	COG2270	Major facilitator Superfamily
K8Z42_23405	COG1116	anion transmembrane transporter activity
K8Z42_23415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z42_23435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z42_23465	COG1263	PTS System
K8Z42_23465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z42_23465	COG2190	(PTS) system
K8Z42_23470	COG0366	Alpha amylase catalytic
K8Z42_23500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z42_23505	COG0549	Belongs to the carbamate kinase family
K8Z42_23530	COG0840	transmembrane signaling receptor activity
K8Z42_23540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z42_23545	COG0765	amino acid transport
K8Z42_23570	COG2814	Major facilitator Superfamily
K8Z42_23575	COG3541	Predicted nucleotidyltransferase
K8Z42_23595	COG5002	protein histidine kinase activity
K8Z42_23620	COG0166	Belongs to the GPI family
K8Z42_23630	COG0492	ferredoxin-NADP+ reductase activity
K8Z42_23635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z42_23640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_23645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_23665	COG0450	alkyl hydroperoxide reductase
K8Z42_23680	COG1473	amidohydrolase
K8Z42_23710	COG4807	Protein conserved in bacteria
K8Z42_23715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z42_23740	COG0730	response to heat
K8Z42_23825	COG0740	serine-type endopeptidase activity
K8Z42_23830	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_23840	COG4626	Terminase
K8Z42_23840	COG1802	Transcriptional regulator
K8Z42_23880	COG0582	viral genome integration into host DNA
K8Z42_23990	COG2002	toxin-antitoxin pair type II binding
K8Z42_24000	COG1484	DNA-dependent DNA replication
K8Z42_24045	COG0582	viral genome integration into host DNA
K8Z42_24055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z42_24070	COG2309	aminopeptidase activity
K8Z42_24080	COG2076	Multidrug Resistance protein
K8Z42_24085	COG1012	belongs to the aldehyde dehydrogenase family
K8Z42_24095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z42_24105	COG1597	lipid kinase activity
K8Z42_24125	COG4682	membrane
K8Z42_24130	COG1846	Transcriptional regulator
K8Z42_24135	COG0003	Pfam Anion-transporting ATPase
K8Z42_24150	COG1464	Belongs to the NlpA lipoprotein family
K8Z42_24155	COG2011	ABC-type metal ion transport system permease component
K8Z42_24165	COG1335	isochorismatase
K8Z42_24180	COG4851	CamS sex pheromone cAM373 precursor
K8Z42_24190	COG0210	DNA helicase
K8Z42_24215	COG0151	Belongs to the GarS family
K8Z42_24225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z42_24235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z42_24250	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z42_24260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z42_24265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z42_24270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z42_24290	COG0463	Glycosyl transferase, family 2
K8Z42_24290	COG1216	Glycosyl transferase, family 2
K8Z42_24300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z42_24355	COG0745	RESPONSE REGULATOR receiver
K8Z42_24360	COG2205	protein histidine kinase activity
K8Z42_24400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z42_24425	COG5002	protein histidine kinase activity
K8Z42_24435	COG2252	PERMEase
K8Z42_24470	COG4824	toxin secretion phage lysis holin
K8Z42_24570	COG0582	viral genome integration into host DNA
K8Z42_24720	COG0582	viral genome integration into host DNA
K8Z42_24785	COG3378	Phage plasmid primase P4 family
K8Z42_24810	COG0582	viral genome integration into host DNA
K8Z42_24825	COG1266	CAAX protease self-immunity
K8Z42_24840	COG0488	(ABC) transporter
K8Z42_24850	COG0456	acetyltransferase
K8Z42_24855	COG1214	PFAM Peptidase M22, glycoprotease
K8Z42_24860	COG0802	atpase or kinase
K8Z42_24960	COG2183	response to ionizing radiation
K8Z42_24965	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z42_24970	COG0864	Transcriptional regulator
K8Z42_24975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z42_24980	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z42_24990	COG0705	Rhomboid family
K8Z42_24995	COG4294	response to UV
K8Z42_25005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z42_25015	COG2814	Major facilitator Superfamily
K8Z42_25020	COG0531	amino acid
K8Z42_25030	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z42_25035	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z42_25065	COG0561	phosphatase activity
K8Z42_25075	COG4608	Belongs to the ABC transporter superfamily
K8Z42_25080	COG0444	Belongs to the ABC transporter superfamily
K8Z42_25085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z42_25100	COG3344	reverse transcriptase
K8Z42_25115	COG0747	negative chemotaxis
K8Z42_25125	COG0488	(ABC) transporter
K8Z42_25145	COG5298	Protein conserved in bacteria
K8Z42_25160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_25170	COG1609	Transcriptional regulator
K8Z42_25180	COG0204	Acyl-transferase
K8Z42_25195	COG0697	spore germination
K8Z42_25210	COG1910	domain protein
K8Z42_25215	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z42_25220	COG4149	molybdate abc transporter
K8Z42_25235	COG0656	L-ascorbic acid biosynthetic process
K8Z42_25245	COG4166	transmembrane transport
K8Z42_25250	COG4166	transmembrane transport
K8Z42_25265	COG2207	Transcriptional regulator
K8Z42_25280	COG2814	Major facilitator Superfamily
K8Z42_25290	COG2271	Major facilitator Superfamily
K8Z42_25295	COG0277	FAD linked oxidase domain protein
K8Z42_25305	COG0604	alcohol dehydrogenase
K8Z42_25310	COG1464	Belongs to the NlpA lipoprotein family
K8Z42_25315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z42_25320	COG2011	ABC-type metal ion transport system permease component
K8Z42_25325	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_25360	COG4856	YbbR-like protein
K8Z42_25365	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z42_25445	COG0726	polysaccharide deacetylase
K8Z42_25450	COG2194	sulfuric ester hydrolase activity
K8Z42_25460	COG0489	protein tyrosine kinase activity
K8Z42_25465	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z42_25490	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z42_25525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z42_25535	COG0024	Methionine aminopeptidase
K8Z42_25545	COG0201	protein transport
K8Z42_25605	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z42_25670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z42_25675	COG1358	cellular component organization or biogenesis
K8Z42_25690	COG2813	Specifically methylates the guanine in position
K8Z42_25710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z42_25715	COG0250	Participates in transcription elongation, termination and antitermination
K8Z42_25720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z42_25735	COG3688	RNA-binding protein containing a PIN domain
K8Z42_25740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z42_25755	COG1045	serine acetyltransferase
K8Z42_25775	COG4956	integral membrane protein (PIN domain superfamily)
K8Z42_25785	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z42_25790	COG0542	response to heat
K8Z42_25800	COG3880	PFAM UvrB UvrC protein
K8Z42_25890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z42_25895	COG1396	sequence-specific DNA binding
K8Z42_25900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z42_25905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z42_25910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z42_25915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z42_25920	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z42_25925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z42_25930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z42_25945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z42_25950	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z42_25960	COG2208	phosphoserine phosphatase activity
K8Z42_25975	COG1098	S1 RNA binding domain
K8Z42_25995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z42_26000	COG3956	TIGRFAM MazG family protein
K8Z42_26005	COG2244	polysaccharide biosynthetic process
K8Z42_26010	COG2002	toxin-antitoxin pair type II binding
K8Z42_26015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z42_26035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K8Z42_26045	COG0251	oxidation-reduction process
K8Z42_26050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z42_26065	COG4466	Protein conserved in bacteria
K8Z42_26085	COG0084	hydrolase, TatD family'
K8Z42_26095	COG2002	toxin-antitoxin pair type II binding
K8Z42_26100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z42_26110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z42_26120	COG1774	PSP1 C-terminal conserved region
K8Z42_26125	COG0470	DNA polymerase III
K8Z42_26135	COG1982	Orn Lys Arg decarboxylase major
K8Z42_26190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z42_26200	COG0590	tRNA wobble adenosine to inosine editing
K8Z42_26205	COG1335	isochorismatase
K8Z42_26210	COG1428	Deoxynucleoside kinase
K8Z42_26215	COG1428	Deoxynucleoside kinase
K8Z42_26245	COG1686	Belongs to the peptidase S11 family
K8Z42_26250	COG0516	GMP reductase activity
K8Z42_26250	COG0517	IMP dehydrogenase activity
K8Z42_26285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z42_26290	COG0187	DNA topoisomerase II activity
K8Z42_26300	COG2501	S4 domain
K8Z42_26305	COG0592	DNA-directed DNA polymerase activity
K8Z42_26315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z42_26330	COG1847	R3H domain protein
K8Z42_26355	COG1192	Involved in chromosome partitioning
K8Z42_26360	COG1475	DNA binding
K8Z42_26370	COG0668	transmembrane transport
K8Z42_26375	COG4481	Protein conserved in bacteria
K8Z42_26380	COG0012	GTP binding
K8Z42_26400	COG4241	membrane
K8Z42_26405	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z42_26415	COG0305	Participates in initiation and elongation during chromosome replication
K8Z42_26445	COG0745	RESPONSE REGULATOR receiver
K8Z42_26450	COG5002	protein histidine kinase activity
K8Z42_26460	COG4853	Protein conserved in bacteria
K8Z42_26465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z42_26470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z42_26485	COG5002	protein histidine kinase activity
K8Z42_26520	COG3344	reverse transcriptase
K8Z42_26540	COG1272	protein, Hemolysin III
K8Z42_26545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z42_26565	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
K8Z42_26570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z42_26575	COG2814	Major facilitator Superfamily
K8Z42_26580	COG3275	phosphorelay sensor kinase activity
K8Z42_26600	COG0628	permease
K8Z42_26605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z42_26605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z42_26610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z42_26615	COG1309	transcriptional regulator
K8Z42_26620	COG0488	(ABC) transporter
K8Z42_26625	COG0463	Glycosyl transferase, family 2
K8Z42_26630	COG4485	Bacterial membrane protein, YfhO
K8Z42_26640	COG1216	Glycosyl transferase, family 2
K8Z42_26655	COG1216	Glycosyl transferase, family 2
K8Z42_26660	COG1607	acyl-coa hydrolase
K8Z42_26670	COG0840	transmembrane signaling receptor activity
K8Z42_26685	COG0438	transferase activity, transferring glycosyl groups
K8Z42_26695	COG0477	Major facilitator Superfamily
K8Z42_26700	COG3279	Response regulator of the LytR AlgR family
K8Z42_26705	COG1966	Carbon starvation protein
K8Z42_26710	COG2879	small protein
K8Z42_26715	COG3706	GGDEF domain
K8Z42_26720	COG0351	phosphomethylpyrimidine kinase
K8Z42_26725	COG4585	Histidine kinase
K8Z42_26725	COG2203	Gaf domain
K8Z42_26730	COG2197	response regulator
K8Z42_26740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z42_26745	COG1011	Hydrolase
K8Z42_26755	COG2873	o-acetylhomoserine
K8Z42_26765	COG0460	homoserine dehydrogenase
K8Z42_26775	COG1609	Transcriptional regulator
K8Z42_26780	COG2755	lipolytic protein G-D-S-L family
K8Z42_26785	COG1131	(ABC) transporter
K8Z42_26790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K8Z42_26800	COG2814	Major facilitator Superfamily
K8Z42_26805	COG0561	phosphatase activity
K8Z42_26810	COG2233	PERMEase
K8Z42_26815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z42_26825	COG2363	Small membrane protein
K8Z42_26835	COG3773	Cell wall hydrolase
K8Z42_26850	COG0280	phosphate acetyltransferase
K8Z42_26870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_26875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z42_26880	COG1120	ATPase activity
K8Z42_26885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z42_26890	COG1078	dGTPase activity
K8Z42_26900	COG1994	Peptidase M50
K8Z42_26910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z42_26915	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z42_26920	COG0789	Transcriptional regulator
K8Z42_26925	COG2814	Major facilitator Superfamily
K8Z42_26950	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z42_26955	COG4506	Protein conserved in bacteria
K8Z42_26965	COG1595	DNA-templated transcription, initiation
K8Z42_26990	COG2234	aminopeptidase activity
K8Z42_27000	COG0024	Methionine aminopeptidase
K8Z42_27005	COG1131	(ABC) transporter
K8Z42_27010	COG0842	Transport permease protein
K8Z42_27015	COG4585	Histidine kinase
K8Z42_27020	COG2197	response regulator
K8Z42_27025	COG3227	Zinc metalloprotease (Elastase)
K8Z42_27040	COG3300	MHYT domain
K8Z42_27040	COG5001	Diguanylate cyclase
K8Z42_27055	COG3344	reverse transcriptase
K8Z42_27070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z42_27075	COG2181	nitrate reductase activity
K8Z42_27075	COG0247	lactate metabolic process
K8Z42_27080	COG0183	Belongs to the thiolase family
K8Z42_27085	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z42_27090	COG1960	acyl-CoA dehydrogenase activity
K8Z42_27095	COG1960	acyl-CoA dehydrogenase activity
K8Z42_27105	COG3343	RNA polymerase activity
K8Z42_27115	COG4821	SIS domain
K8Z42_27135	COG1494	fructose-1,6-bisphosphatase
K8Z42_27140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z42_27175	COG0009	L-threonylcarbamoyladenylate synthase
K8Z42_27190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z42_27195	COG2259	Doxx family
K8Z42_27210	COG0698	ribose 5-phosphate isomerase
K8Z42_27245	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z42_27310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z42_27330	COG0839	Belongs to the complex I subunit 6 family
K8Z42_27340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z42_27345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z42_27350	COG1007	ATP synthesis coupled electron transport
K8Z42_27355	COG4836	Membrane
K8Z42_27370	COG2385	sporulation resulting in formation of a cellular spore
K8Z42_27375	COG3279	Response regulator of the LytR AlgR family
K8Z42_27390	COG0739	heme binding
K8Z42_27400	COG1609	Transcriptional regulator
K8Z42_27415	COG0489	protein tyrosine kinase activity
K8Z42_27420	COG3944	biosynthesis protein
K8Z42_27425	COG0489	protein tyrosine kinase activity
K8Z42_27430	COG4464	protein tyrosine phosphatase activity
K8Z42_27435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z42_27450	COG1216	Glycosyl transferase, family 2
K8Z42_27460	COG0438	transferase activity, transferring glycosyl groups
K8Z42_27465	COG0463	Glycosyl transferase, family 2
K8Z42_27470	COG1215	transferase activity, transferring glycosyl groups
K8Z42_27475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z42_27480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z42_27485	COG1316	TRANSCRIPTIONal
K8Z42_27495	COG0745	RESPONSE REGULATOR receiver
K8Z42_27500	COG5002	protein histidine kinase activity
K8Z42_27525	COG1136	(ABC) transporter
K8Z42_27530	COG0577	efflux transmembrane transporter activity
K8Z42_27570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z42_27575	COG4715	Zinc finger, swim domain protein
K8Z42_27600	COG3584	3D domain protein
K8Z42_27600	COG1388	LysM domain
K8Z42_27605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z42_27610	COG1215	transferase activity, transferring glycosyl groups
K8Z42_27620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z42_27625	COG1388	LysM domain
K8Z42_27625	COG0791	NLP P60 protein
K8Z42_27635	COG1368	sulfuric ester hydrolase activity
K8Z42_27645	COG2389	metal-binding protein
K8Z42_27660	COG1620	l-lactate permease
K8Z42_27670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z42_27675	COG1294	oxidase, subunit
K8Z42_27680	COG1271	oxidase subunit
K8Z42_27690	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K8Z42_27695	COG0583	DNA-binding transcription factor activity
K8Z42_27700	COG1511	domain protein
K8Z42_27715	COG1301	dicarboxylic acid transport
K8Z42_27720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z42_27730	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z42_27740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z42_27745	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z42_27750	COG1486	melibiose metabolic process
K8Z42_27770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z42_27770	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z42_27780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z42_27785	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z42_27790	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z42_27795	COG1316	TRANSCRIPTIONal
K8Z42_27800	COG1739	Uncharacterized protein family UPF0029
K8Z42_27805	COG1307	EDD domain protein, DegV family
K8Z42_27810	COG1733	regulation of RNA biosynthetic process
K8Z42_27815	COG0791	NLP P60 protein
K8Z42_27815	COG1388	LysM domain
K8Z42_27820	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z42_27825	COG1040	competence protein
K8Z42_27830	COG1278	Cold shock
K8Z42_27835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z42_27865	COG1131	(ABC) transporter
K8Z42_27890	COG2884	Cell division ATP-binding protein ftsE
K8Z42_27895	COG2177	Part of the ABC transporter FtsEX involved in
K8Z42_27900	COG0793	Belongs to the peptidase S41A family
K8Z42_27900	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_27905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z42_27910	COG1132	(ABC) transporter
K8Z42_27920	COG0488	(ABC) transporter
K8Z42_27925	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z42_27935	COG0583	DNA-binding transcription factor activity
K8Z42_27955	COG0789	Transcriptional regulator
K8Z42_27970	COG0556	nucleotide-excision repair
K8Z42_27975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z42_27985	COG1950	PFAM Membrane protein of
K8Z42_28005	COG0110	maltose O-acetyltransferase activity
K8Z42_28010	COG0457	Tetratricopeptide repeat
K8Z42_28015	COG0492	ferredoxin-NADP+ reductase activity
K8Z42_28025	COG1051	belongs to the nudix hydrolase family
K8Z42_28035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z42_28045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z42_28055	COG2323	membrane
K8Z42_28070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z42_28095	COG0582	viral genome integration into host DNA
K8Z42_28125	COG3646	Phage regulatory protein
K8Z42_28210	COG3331	DNA recombination
K8Z42_28350	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_28355	COG4824	toxin secretion phage lysis holin
K8Z42_28360	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_28365	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_28365	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_28365	COG1388	LysM domain
K8Z42_28370	COG0457	Tetratricopeptide repeat
K8Z42_28400	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z42_28415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z42_28450	COG1346	cytolysis
K8Z42_28455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z42_28460	COG1647	Serine aminopeptidase, S33
K8Z42_28465	COG0557	exoribonuclease II activity
K8Z42_28490	COG3344	reverse transcriptase
K8Z42_28505	COG0745	RESPONSE REGULATOR receiver
K8Z42_28550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_28555	COG0488	(ABC) transporter
K8Z42_28610	COG1252	NADH dehydrogenase
K8Z42_28620	COG1733	regulation of RNA biosynthetic process
K8Z42_28625	COG2814	Major facilitator Superfamily
K8Z42_28630	COG0656	L-ascorbic acid biosynthetic process
K8Z42_28645	COG2910	NAD(P)H-binding
K8Z42_28650	COG1115	amino acid carrier protein
K8Z42_28655	COG1115	amino acid carrier protein
K8Z42_28680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z42_28685	COG2311	Membrane
K8Z42_28690	COG1528	Iron-storage protein
K8Z42_28700	COG1611	Belongs to the LOG family
K8Z42_28715	COG0783	Belongs to the Dps family
K8Z42_28720	COG1115	amino acid carrier protein
K8Z42_28725	COG0490	domain, Protein
K8Z42_28730	COG0475	glutathione-regulated potassium exporter activity
K8Z42_28735	COG0586	Pfam SNARE associated Golgi protein
K8Z42_28755	COG3227	Zinc metalloprotease (Elastase)
K8Z42_28760	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z42_28765	COG0840	transmembrane signaling receptor activity
K8Z42_28795	COG5002	protein histidine kinase activity
K8Z42_28800	COG0745	RESPONSE REGULATOR receiver
K8Z42_28805	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z42_28815	COG0586	Pfam SNARE associated Golgi protein
K8Z42_28850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_28870	COG0531	amino acid
K8Z42_28875	COG2814	Major facilitator Superfamily
K8Z42_28890	COG0840	transmembrane signaling receptor activity
K8Z42_28895	COG0011	TIGRFAM Protein of
K8Z42_28910	COG1686	Belongs to the peptidase S11 family
K8Z42_28920	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z42_28920	COG1024	Enoyl-CoA hydratase
K8Z42_28925	COG0183	Belongs to the thiolase family
K8Z42_28930	COG1960	acyl-CoA dehydrogenase activity
K8Z42_28935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z42_28940	COG1309	transcriptional regulator
K8Z42_28955	COG0039	L-malate dehydrogenase activity
K8Z42_28975	COG1393	Belongs to the ArsC family
K8Z42_28985	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z42_28990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z42_29005	COG2011	ABC-type metal ion transport system permease component
K8Z42_29010	COG1464	Belongs to the NlpA lipoprotein family
K8Z42_29015	COG1464	Belongs to the NlpA lipoprotein family
K8Z42_29020	COG0396	ATPase activity
K8Z42_29025	COG0719	Fe-S assembly protein
K8Z42_29030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z42_29035	COG0822	iron-sulfur transferase activity
K8Z42_29040	COG0719	Fe-S assembly protein
K8Z42_29045	COG0737	Belongs to the 5'-nucleotidase family
K8Z42_29050	COG3377	Domain of unknown function (DUF1805)
K8Z42_29060	COG0739	heme binding
K8Z42_29085	COG4377	Putative membrane peptidase family (DUF2324)
K8Z42_29090	COG0789	Transcriptional regulator
K8Z42_29100	COG4470	Protein conserved in bacteria
K8Z42_29120	COG1494	fructose-1,6-bisphosphatase
K8Z42_29125	COG2445	Protein of unknown function DUF86
K8Z42_29135	COG0647	UMP catabolic process
K8Z42_29140	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z42_29150	COG1358	cellular component organization or biogenesis
K8Z42_29170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z42_29175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z42_29185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z42_29190	COG4837	Protein of unknown function (DUF1462)
K8Z42_29235	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z42_29240	COG0390	transport system, permease component
K8Z42_29255	COG1252	NADH dehydrogenase
K8Z42_29270	COG0316	Belongs to the HesB IscA family
K8Z42_29310	COG1396	sequence-specific DNA binding
K8Z42_29405	COG0582	viral genome integration into host DNA
K8Z42_29520	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_29530	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_29530	COG1388	LysM domain
K8Z42_29530	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_29535	COG0739	heme binding
K8Z42_29540	COG0741	lytic transglycosylase activity
K8Z42_29570	COG1361	Conserved repeat domain
K8Z42_29585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z42_29590	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K8Z42_29595	COG1687	branched-chain amino acid
K8Z42_29620	COG2233	PERMEase
K8Z42_29625	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z42_29630	COG0288	reversible hydration of carbon dioxide
K8Z42_29635	COG1522	sequence-specific DNA binding
K8Z42_29660	COG0542	response to heat
K8Z42_29665	COG0494	nUDIX hydrolase
K8Z42_29670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K8Z42_29680	COG0457	Tetratricopeptide repeat
K8Z42_29815	COG3344	reverse transcriptase
K8Z42_29825	COG3344	reverse transcriptase
K8Z42_29970	COG3711	transcriptional antiterminator
K8Z42_29975	COG1263	PTS System
K8Z42_29975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z42_29975	COG2190	(PTS) system
K8Z42_29980	COG2723	6-phospho-beta-galactosidase activity
K8Z42_30015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_30055	COG3344	reverse transcriptase
K8Z42_30065	COG3344	reverse transcriptase
K8Z42_30115	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_30195	COG3344	reverse transcriptase
K8Z42_30210	COG4974	Belongs to the 'phage' integrase family
K8Z42_30225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z42_30240	COG1073	alpha beta
K8Z42_30245	COG3104	oligopeptide transport
K8Z42_30280	COG2259	Doxx family
K8Z42_30285	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_30310	COG2814	Major facilitator Superfamily
K8Z42_30325	COG0577	efflux transmembrane transporter activity
K8Z42_30330	COG1136	(ABC) transporter
K8Z42_30340	COG0745	RESPONSE REGULATOR receiver
K8Z42_30345	COG3850	Histidine kinase
K8Z42_30345	COG5002	protein histidine kinase activity
K8Z42_30375	COG1183	phosphatidylcholine synthase activity
K8Z42_30405	COG0457	Tetratricopeptide repeat
K8Z42_30475	COG1132	(ABC) transporter
K8Z42_30480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z42_30490	COG1131	(ABC) transporter
K8Z42_30510	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8Z42_30540	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_30540	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_30590	COG1132	(ABC) transporter
K8Z42_30610	COG1475	DNA binding
K8Z42_30665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z42_30670	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_30670	COG0300	oxidoreductase activity
K8Z42_30670	COG3321	synthase
K8Z42_30670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z42_30670	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_30685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z42_30690	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z42_30705	COG1960	acyl-CoA dehydrogenase activity
K8Z42_30725	COG0300	oxidoreductase activity
K8Z42_30725	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_30725	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_30725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z42_30725	COG0300	oxidoreductase activity
K8Z42_30725	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z42_30725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z42_30725	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z42_30725	COG3321	synthase
K8Z42_30725	COG3321	synthase
K8Z42_30740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K8Z42_30755	COG0667	Aldo Keto reductase
K8Z42_30780	COG1396	sequence-specific DNA binding
K8Z42_30795	COG3344	reverse transcriptase
K8Z42_30830	COG0457	Tetratricopeptide repeat
K8Z42_30845	COG0210	DNA helicase
K8Z42_30885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z42_30895	COG0457	Tetratricopeptide repeat
K8Z42_30905	COG0456	acetyltransferase
K8Z42_30905	COG1846	Transcriptional regulator
K8Z42_30945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z42_30975	COG0457	Tetratricopeptide repeat
K8Z42_30980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z42_30995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K8Z42_31050	COG0367	asparagine synthase
K8Z42_31055	COG1309	transcriptional regulator
K8Z42_31070	COG1136	(ABC) transporter
K8Z42_31170	COG0583	DNA-binding transcription factor activity
K8Z42_31175	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z42_31220	COG0730	response to heat
K8Z42_31245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z42_31275	COG2002	toxin-antitoxin pair type II binding
K8Z42_31280	COG4166	transmembrane transport
K8Z42_31300	COG4974	Belongs to the 'phage' integrase family
K8Z42_31355	COG0653	protein targeting
K8Z42_31370	COG0457	Tetratricopeptide repeat
K8Z42_31400	COG0697	spore germination
K8Z42_31410	COG3344	reverse transcriptase
K8Z42_31435	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z42_31460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z42_31475	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_31475	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_31515	COG0659	secondary active sulfate transmembrane transporter activity
K8Z42_31520	COG0589	response to stress
K8Z42_31525	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z42_31535	COG2323	membrane
K8Z42_31540	COG1522	sequence-specific DNA binding
K8Z42_31545	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z42_31595	COG4824	toxin secretion phage lysis holin
K8Z42_31650	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_31650	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_31655	COG0475	glutathione-regulated potassium exporter activity
K8Z42_31660	COG0490	domain, Protein
K8Z42_31665	COG0840	transmembrane signaling receptor activity
K8Z42_31720	COG0583	DNA-binding transcription factor activity
K8Z42_31730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z42_31765	COG0640	Transcriptional regulator
K8Z42_31805	COG0675	Transposase, IS605 OrfB family
K8Z42_31815	COG2828	Protein conserved in bacteria
K8Z42_31850	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z42_31885	COG0457	Tetratricopeptide repeat
K8Z42_32170	COG0592	DNA-directed DNA polymerase activity
K8Z42_32175	COG4712	double-strand break repair protein
K8Z42_32210	COG3344	reverse transcriptase
K8Z42_32220	COG3344	reverse transcriptase
K8Z42_32450	COG3344	reverse transcriptase
K8Z42_32460	COG3344	reverse transcriptase
K8Z42_32515	COG2311	Membrane
K8Z42_32535	COG0457	Tetratricopeptide repeat
K8Z42_32600	COG0741	lytic transglycosylase activity
K8Z42_32600	COG0791	NLP P60 protein
K8Z42_32675	COG2323	membrane
K8Z42_32680	COG1522	sequence-specific DNA binding
K8Z42_32685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z42_32870	COG0457	Tetratricopeptide repeat
K8Z42_32915	COG0739	heme binding
K8Z42_33110	COG2323	membrane
K8Z42_33115	COG1522	sequence-specific DNA binding
K8Z42_33120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z42_33155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z42_33245	COG1923	regulation of RNA biosynthetic process
K8Z42_33255	COG0457	Tetratricopeptide repeat
K8Z42_33450	COG0791	NLP P60 protein
K8Z42_33450	COG0741	lytic transglycosylase activity
K8Z42_33480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z42_33690	COG3344	reverse transcriptase
K8Z42_33695	COG0791	NLP P60 protein
K8Z42_33695	COG0741	lytic transglycosylase activity
K8Z42_33780	COG0551	DNA topoisomerase type I activity
K8Z42_33780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z42_33830	COG0457	Tetratricopeptide repeat
K8Z42_33835	COG4166	transmembrane transport
K8Z42_33875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z42_33925	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_33925	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_34070	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z42_34140	COG1476	TRANSCRIPTIONal
K8Z42_34145	COG2197	response regulator
K8Z42_34155	COG1073	alpha beta
K8Z42_34215	COG5484	DNA packaging
K8Z42_34215	COG3728	DNA packaging
K8Z42_34315	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z42_34315	COG1388	LysM domain
K8Z42_34315	COG3409	Peptidoglycan-binding domain 1 protein
K8Z42_34370	COG1396	sequence-specific DNA binding
K8Z42_34495	COG3331	DNA recombination
K8Z42_34555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z42_34815	COG0457	Tetratricopeptide repeat
K8Z42_34915	COG3654	unkown
K8Z42_34935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair