locus-tag class description BT10792_00040 ENOG4108SVB resolvase BT10792_00105 ENOG4105BZ1 (ABC) transporter BT10792_00145 ENOG41067MG lrgb family BT10792_00195 ENOG4107QIV Cytochrome c biogenesis protein BT10792_00230 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BT10792_00255 ENOG4108903 Formimidoylglutamase BT10792_00260 ENOG4108VJ1 Transcriptional regulator (CarD family BT10792_00265 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BT10792_00340 ENOG4108IMY Transcriptional regulator BT10792_00345 ENOG4105CEY Amp-dependent synthetase and ligase BT10792_00350 ENOG4107ZYJ bioY protein BT10792_00355 ENOG4107F3J Amp-dependent synthetase and ligase BT10792_00375 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BT10792_00385 ENOG4105E5W Transporter BT10792_00425 ENOG4108JJA ABC, transporter BT10792_00440 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BT10792_00470 ENOG4105W8X HesB YadR YfhF-family protein BT10792_00475 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BT10792_00490 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_00495 ENOG4105C0H protease BT10792_00500 ENOG4105K4P CoA-binding domain protein BT10792_00520 ENOG4105D9R oxidoreductase BT10792_00540 ENOG4105CIG ABC transporter BT10792_00650 ENOG4108JB9 formate dehydrogenase BT10792_00660 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BT10792_00665 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BT10792_00680 ENOG4105TMB Formate nitrite transporter BT10792_00685 ENOG4105D06 uba thif-type nad fad binding protein BT10792_00690 ENOG4105CVM Molybdenum cofactor synthesis domain protein BT10792_00695 ENOG4108ZAF Molybdopterin BT10792_00705 ENOG4105D1F ATP-binding protein BT10792_00720 ENOG410696E Membrane BT10792_00725 ENOG4105FR1 rard protein BT10792_00745 ENOG4105CHR reductase BT10792_00785 ENOG410904N short-chain dehydrogenase reductase BT10792_00805 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BT10792_00825 ENOG4105VEQ Cold shock protein BT10792_00855 ENOG41073R8 VanW family BT10792_00900 ENOG4105BZU Histidine kinase BT10792_00920 ENOG4107DUR UPF0457 protein BT10792_00925 ENOG4108VXD carboxy-peptidase BT10792_00940 ENOG41067SE Tetr family transcriptional regulator BT10792_01005 ENOG4108M1A Chitin-binding protein BT10792_01010 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C BT10792_01040 ENOG4105CQB FAD linked oxidase domain protein BT10792_01070 ENOG4107JM4 Tetratricopeptide repeat BT10792_01085 ENOG41082BM Transcriptional regulator, arsr family BT10792_01135 ENOG4105FFC UPF0187 protein BT10792_01170 ENOG4105E5K Alpha-amylase BT10792_01180 ENOG4105C98 muts2 protein BT10792_01215 ENOG4107CUJ Protein of unknown function (DUF2690) BT10792_01245 ENOG4105EHG Permease protein BT10792_01250 ENOG4108MES Periplasmic binding protein BT10792_01265 ENOG4107R3E Citrate transporter BT10792_01275 ENOG4108TN2 lmbE family BT10792_01350 ENOG4105H3G oxidoreductase BT10792_01385 ENOG4107YXZ hydrolase, family 25 BT10792_01400 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BT10792_01405 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BT10792_01495 ENOG4105KVH Transcriptional regulator BT10792_01515 ENOG4106PGW Short-chain dehydrogenase reductase Sdr BT10792_01575 ENOG4105KVH Transcriptional regulator BT10792_01580 ENOG4105KVH Transcriptional regulator BT10792_01600 ENOG4108TZY GntR Family Transcriptional Regulator BT10792_01640 ENOG4105C44 Serine transporter BT10792_01660 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BT10792_01680 ENOG41090KN UPF0303 protein BT10792_01690 ENOG4105F27 Major Facilitator BT10792_01695 ENOG4105CV8 reductase BT10792_01710 ENOG4105KVH Transcriptional regulator BT10792_01715 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BT10792_01725 ENOG4108UX3 '-nucleotidase BT10792_01730 ENOG4105C8Q Methyl-accepting chemotaxis BT10792_01760 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BT10792_01770 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BT10792_01775 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BT10792_01780 ENOG4105CV1 Transketolase (EC 2.2.1.1) BT10792_01810 ENOG4105XDF Protein of unknown function (DUF1272) BT10792_01940 ENOG4105C31 Tryptophanyl-tRNA synthetase BT10792_01945 ENOG4108UW5 maltose o-acetyltransferase BT10792_02035 ENOG4108PSK reductase BT10792_02070 ENOG4108RCM Nitroreductase BT10792_02075 ENOG4105KVH Transcriptional regulator BT10792_02090 ENOG4105CUT histidyl-tRNA synthetase BT10792_02095 ENOG4108Z66 YbaK ebsC protein BT10792_02120 ENOG41067QW Transcriptional regulator BT10792_02215 ENOG4105CRW Short chain fatty acid transporter BT10792_02240 ENOG4105CZM Major Facilitator BT10792_02245 ENOG4107MII Sugar-specific transcriptional regulator TrmB BT10792_02260 ENOG4108ISG Major Facilitator BT10792_02295 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BT10792_02315 ENOG410874W AraC family transcriptional regulator BT10792_02325 ENOG41082W1 Cupin 2, conserved barrel domain protein BT10792_02385 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BT10792_02395 ENOG4105BZU Histidine kinase BT10792_02415 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BT10792_02425 ENOG4105DNP FAD linked oxidase domain protein BT10792_02440 ENOG4105JQZ Methyltransferase BT10792_02505 ENOG4105C0R drug resistance transporter emrb qaca subfamily BT10792_02510 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BT10792_02590 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_02620 ENOG4105N0V mono-oxygenase ydhR BT10792_02685 ENOG4108YXU transcriptional regulator AsnC family BT10792_02690 ENOG4105CHR reductase BT10792_02695 ENOG4105M4P Tetr family transcriptional regulator BT10792_02700 ENOG4105F27 Major Facilitator BT10792_02760 ENOG4105NAE bifunctional deaminase-reductase domain protein BT10792_02775 ENOG41085FC arsR family transcriptional regulator BT10792_02785 ENOG4105D6J arsenicaL-resistance protein BT10792_02810 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BT10792_02815 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BT10792_02820 ENOG4108TWJ NADH dehydrogenase subunit 5 BT10792_02835 ENOG4105CVP deoxyribo-dipyrimidine photolyase BT10792_02840 ENOG4108606 TspO/MBR family BT10792_02935 ENOG4105CHJ isochorismatase hydrolase BT10792_03000 ENOG4105DWD nucleoside recognition domain protein BT10792_03015 ENOG4105FDT acyl-CoA dehydrogenase BT10792_03025 ENOG4108ZHR arsR family transcriptional regulator BT10792_03030 ENOG4106N3A copper homeostasis protein cutc BT10792_03045 ENOG4107258 Transcriptional regulator BT10792_03050 ENOG4105P4J Allophanate hydrolase, subunit 1 BT10792_03060 ENOG4105E7W lamb ycsf family protein BT10792_03075 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BT10792_03080 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BT10792_03120 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BT10792_03130 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_03145 ENOG4105F1N DNA alkylation repair BT10792_03155 ENOG4108IQI permease BT10792_03235 ENOG4108DMH HTH_ARAC BT10792_03260 ENOG4105CMR udp-glucose 4-epimerase BT10792_03265 ENOG4105WEC Molybdate metabolism regulator BT10792_03290 ENOG4105FS7 Transcriptional regulator BT10792_03295 ENOG4108TVJ Nitroreductase BT10792_03355 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BT10792_03405 ENOG4105VMP Transcriptional regulator BT10792_03420 ENOG4107RBI VanW family BT10792_03435 ENOG4105ECK Fatty Acid Desaturase BT10792_03440 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BT10792_03470 ENOG4107258 Transcriptional regulator BT10792_03505 ENOG4105YVS arsR family transcriptional regulator BT10792_03515 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BT10792_03525 ENOG41061GT Aldolase BT10792_03545 ENOG4105C2J ABC transporter BT10792_03550 ENOG4105C2J ABC transporter BT10792_03565 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BT10792_03575 ENOG4105D4B ABC, transporter BT10792_03600 ENOG4105DNP FAD linked oxidase domain protein BT10792_03615 ENOG41069ER domain protein BT10792_03675 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BT10792_03685 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BT10792_03725 ENOG4105C5H ABC transporter BT10792_03735 ENOG4108ZCF integral membrane protein BT10792_03745 ENOG4107VMI polysaccharide deacetylase BT10792_03760 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BT10792_03810 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BT10792_03845 ENOG4105D7T ABC transporter BT10792_03855 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BT10792_03860 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BT10792_03930 ENOG4105DVE abc transporter atp-binding protein BT10792_04015 ENOG4107BMA Transglycosylase associated protein BT10792_04090 ENOG4105EPR degv family BT10792_04135 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BT10792_04170 ENOG4107SET aldo keto reductase BT10792_04185 ENOG4105DTQ mandelate racemase muconate lactonizing BT10792_04205 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BT10792_04215 ENOG4107T5V SNARE associated Golgi BT10792_04255 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BT10792_04270 ENOG4105CTU Proline racemase BT10792_04275 ENOG4105CTU Proline racemase BT10792_04280 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BT10792_04285 ENOG4105C26 Dehydrogenase BT10792_04310 ENOG4108M1A Chitin-binding protein BT10792_04395 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BT10792_04445 ENOG4105MSB protein, conserved in bacteria BT10792_04470 ENOG41087PP glycosyltransferase MGT family BT10792_04485 ENOG41082BV acetyltransferase BT10792_04490 ENOG4105E66 phosphoriboisomerase A BT10792_04515 ENOG4108IJ7 Glycine betaine BT10792_04520 ENOG4107SQ8 Glycine betaine BT10792_04560 ENOG4105RHY Pfam:UPF0157 BT10792_04605 ENOG41062ES Transcriptional regulator BT10792_04620 ENOG4105E98 transcriptional regulator DeoR family BT10792_04675 ENOG4107Z3H Transcriptional regulator, TetR family BT10792_04680 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BT10792_04685 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BT10792_04760 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BT10792_04775 ENOG4105FDR Membrane BT10792_04780 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) BT10792_04790 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BT10792_04815 ENOG4108IUM Glycogen debranching enzyme BT10792_04870 ENOG4105XDF Protein of unknown function (DUF1272) BT10792_04915 ENOG4107VFR oxidoreductase BT10792_04995 ENOG4108NRW Phospholipase, patatin family BT10792_05025 ENOG4108XI2 Domain of unknown function (DUF1963) BT10792_05080 ENOG4105E09 nadh pyrophosphatase BT10792_05170 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BT10792_05255 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BT10792_05260 ENOG4105CB2 alcohol dehydrogenase BT10792_05380 ENOG4105BZU Histidine kinase BT10792_05385 ENOG410667J hydrolase BT10792_05490 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BT10792_05565 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BT10792_05805 ENOG4105ETU transcriptional activator (TenA BT10792_05810 ENOG4105CPF Cell wall formation (By similarity) BT10792_05905 ENOG4105DK7 lysyl-tRNA synthetase BT10792_05915 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BT10792_05935 ENOG410900G Protein of unknown function (DUF421) BT10792_05945 ENOG4105CPQ Dehydrogenase BT10792_05960 ENOG4105EFA 4-hydroxyphenylacetate BT10792_06030 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BT10792_06090 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BT10792_06160 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BT10792_06165 ENOG4107QX3 carboxylase BT10792_06170 ENOG4105E39 Enoyl-CoA hydratase BT10792_06175 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BT10792_06180 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BT10792_06185 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BT10792_06190 ENOG4105C1G acyl-Coa dehydrogenase BT10792_06215 ENOG4105CJ1 ABC, transporter BT10792_06225 ENOG4105DIN metallophosphoesterase BT10792_06280 ENOG41085W3 Transposase BT10792_06345 ENOG4107S9D Alpha beta hydrolase BT10792_06415 ENOG4105CUB amino acid BT10792_06535 ENOG4105EQK -acetyltransferase BT10792_06540 ENOG4105EJ9 Membrane BT10792_06550 ENOG4105KRN Transcriptional regulator, abrb family BT10792_06645 ENOG4108I0C methyltransferase BT10792_06655 ENOG41088CC tellurite resistance protein tehB BT10792_06700 ENOG4105C1J atp-dependent rna helicase BT10792_06730 ENOG4108INS Transcriptional regulator BT10792_06735 ENOG4105C7B Threonine dehydratase BT10792_06745 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BT10792_06780 ENOG4105F32 YngK protein BT10792_06805 ENOG4108KPJ rna polymerase sigma factor BT10792_06845 ENOG4108JCI Transcriptional regulator BT10792_06865 ENOG4108IBT Inherit from COG: transposase BT10792_06875 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BT10792_07055 ENOG41068WN BT10792_07090 ENOG4105WCN acetyltransferase BT10792_07125 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BT10792_07135 ENOG4107MII Sugar-specific transcriptional regulator TrmB BT10792_07150 ENOG4108Y4K DNA-binding transcriptional activator BT10792_07165 ENOG41081I9 integral membrane protein BT10792_07215 ENOG4105C19 ABC transporter BT10792_07220 ENOG4105C22 threonyL-tRNA synthetase BT10792_07225 ENOG4105FE9 pseudouridine synthase BT10792_07265 ENOG4105K70 DNA-binding protein BT10792_07285 ENOG4105WQT MbtH domain protein BT10792_07290 ENOG4105CEY Amp-dependent synthetase and ligase BT10792_07295 ENOG4105WQI isochorismatase BT10792_07300 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BT10792_07305 ENOG4105E4F Isochorismate synthase BT10792_07310 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BT10792_07345 ENOG4105EYH Exonuclease BT10792_07350 ENOG4107RFY SbcCD D subunit BT10792_07365 ENOG4105E39 Enoyl-CoA hydratase BT10792_07380 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BT10792_07395 ENOG4105DXD 2-methylcitrate dehydratase BT10792_07405 ENOG4105W8X HesB YadR YfhF-family protein BT10792_07410 ENOG4105CZM Major Facilitator BT10792_07420 ENOG4105BZ4 penicillin-binding protein BT10792_07475 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BT10792_07520 ENOG4105SZ6 Thioredoxin BT10792_07590 ENOG4108TSC N-acetyltransferase BT10792_07595 ENOG4107S4Y M20 DapE family protein YgeY BT10792_07640 ENOG4105C37 (CBS) domain BT10792_07680 ENOG4105E90 ABC transporter BT10792_07725 ENOG4105C6Z Gluconate BT10792_07730 ENOG4105CMG Carbohydrate kinase BT10792_07765 ENOG4107ZY0 Phenazine biosynthesis-like protein BT10792_07770 ENOG4106KNT transcriptional regulator BT10792_07775 ENOG4105WH1 Two component transcriptional regulator luxr family BT10792_07780 ENOG4105BZU Histidine kinase BT10792_07785 ENOG4105D8X mechanosensitive ion channel BT10792_07815 ENOG4105F0I Aminotransferase BT10792_07820 ENOG4108MES Periplasmic binding protein BT10792_07825 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BT10792_07840 ENOG4105CAQ asparagine synthetase BT10792_07845 ENOG4107Y70 Heat shock protein BT10792_07850 ENOG4108KF3 Electron transport protein SCO1 SenC BT10792_07885 ENOG4108UT2 hemolysin iii BT10792_07955 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BT10792_07960 ENOG4105VMP Transcriptional regulator BT10792_07970 ENOG4105KD7 acetyltransferase BT10792_08165 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BT10792_08185 ENOG4107YX5 Pfam:DUF548 BT10792_08215 ENOG4108UUM single-stranded DNA-binding protein BT10792_08230 ENOG4105C5H ABC transporter BT10792_08260 ENOG4105MCT stage V sporulation protein S BT10792_08300 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BT10792_08305 ENOG4108IFG nitrite reductase, (NAD(P)H) BT10792_08310 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BT10792_08315 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BT10792_08325 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BT10792_08350 ENOG4108ZAF Molybdopterin BT10792_08370 ENOG4107V6Q Cyclic nucleotide-binding domain BT10792_08380 ENOG4105R3A Nitrate reductase BT10792_08385 ENOG4108IUE nitrate reductase beta subunit BT10792_08395 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BT10792_08410 ENOG4108V06 Glutathione peroxidase BT10792_08420 ENOG4105CNW domain protein BT10792_08435 ENOG4105EMN RNA polymerase sigma factor BT10792_08450 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BT10792_08455 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BT10792_08500 ENOG4105KBJ sporulation protein ytfj BT10792_08550 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BT10792_08585 ENOG4108JYZ YitT family BT10792_08590 ENOG41087PP glycosyltransferase MGT family BT10792_08605 ENOG4107RBS Methyltransferase BT10792_08710 ENOG4108Z7R Chaperone CsaA BT10792_08775 ENOG4108S4H thioesterase Superfamily protein BT10792_08800 ENOG4107T5V SNARE associated Golgi BT10792_08875 ENOG4105CKI cobalamin synthesis protein BT10792_08880 ENOG4107QM2 Aldo Keto reductase BT10792_08915 ENOG4108WPJ Ferritin-like domain BT10792_08940 ENOG4105C8Q Methyl-accepting chemotaxis BT10792_08970 ENOG4105CPC Aldo Keto reductase BT10792_08975 ENOG4105YVS arsR family transcriptional regulator BT10792_08985 ENOG4105KRN Transcriptional regulator, abrb family BT10792_09040 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BT10792_09050 ENOG4105YWU small acid-soluble spore protein BT10792_09055 ENOG4108WBH protein TIM barrel BT10792_09070 ENOG4105CEY Amp-dependent synthetase and ligase BT10792_09085 ENOG4105VRR gCN5-related N-acetyltransferase BT10792_09090 ENOG4105KT7 mgtC SapB transporter BT10792_09100 ENOG4107VMI polysaccharide deacetylase BT10792_09110 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BT10792_09135 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BT10792_09170 ENOG4108ZJ4 polysaccharide deacetylase BT10792_09195 ENOG4105BZU Histidine kinase BT10792_09200 ENOG4105EFI regulatoR BT10792_09205 ENOG4105BZ1 (ABC) transporter BT10792_09270 ENOG4105K64 Glycosyl transferase, family 2 BT10792_09280 ENOG4108JJ8 (ABC) transporter BT10792_09285 ENOG4108JJ9 ABC, transporter BT10792_09290 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BT10792_09295 ENOG4105C4M (Ubiquinol oxidase) subunit I BT10792_09325 ENOG4105EGI Transcriptional regulator BT10792_09340 ENOG4108IV0 ABC, transporter BT10792_09345 ENOG4105C0Z ABC transporter BT10792_09355 ENOG4105CKI cobalamin synthesis protein BT10792_09370 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BT10792_09375 ENOG4106F5Q Membrane BT10792_09470 ENOG4105XSJ toxin secretion phage lysis holin BT10792_09615 ENOG4105KRN Transcriptional regulator, abrb family BT10792_09705 ENOG4105C2M dna polymerase I BT10792_09780 ENOG41085W3 Transposase BT10792_09825 ENOG4108TVJ Nitroreductase BT10792_09830 ENOG4107ZXU DSBA oxidoreductase BT10792_09845 ENOG4107RT3 EamA-like transporter family BT10792_09850 ENOG4105KTB nuclear export factor GLE1 BT10792_09900 ENOG4107R16 Multicopper oxidase BT10792_09910 ENOG4107RAQ aminopeptidase BT10792_09955 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BT10792_09960 ENOG4105D9N nucleoside BT10792_09970 ENOG4107RHR regulatoR BT10792_09995 ENOG410849A acetyltransferase, (GNAT) family BT10792_10050 ENOG4105C0X amino acid BT10792_10055 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BT10792_10070 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BT10792_10120 ENOG4105EQ0 Major Facilitator superfamily BT10792_10125 ENOG4105EQ0 Major Facilitator superfamily BT10792_10145 ENOG4105CYC Transferase BT10792_10150 ENOG4105DY9 regulatoR BT10792_10195 ENOG4105C7B Threonine dehydratase BT10792_10205 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BT10792_10215 ENOG4105C7K acetolactate synthase BT10792_10220 ENOG4105CM2 brancheD-chain amino acid aminotransferase BT10792_10225 ENOG4105CHR reductase BT10792_10230 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BT10792_10260 ENOG4105H67 Protein of unknown function (DUF421) BT10792_10265 ENOG4105X5K response regulator receiver protein BT10792_10275 ENOG4105C8J )-transporter BT10792_10305 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BT10792_10430 ENOG4105C6K Malic enzyme BT10792_10435 ENOG4108IJ0 Aspartate ammonia-lyase BT10792_10465 ENOG4105CJ1 ABC, transporter BT10792_10505 ENOG4106BRA Membrane BT10792_10510 ENOG4105BZC d-serine deaminase BT10792_10525 ENOG4107JM4 Tetratricopeptide repeat BT10792_10535 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BT10792_10540 ENOG4107QIV Cytochrome c biogenesis protein BT10792_10560 ENOG4105EC3 peptidase S51, dipeptidase E BT10792_10565 ENOG4107QJQ Mate efflux family protein BT10792_10645 ENOG4105PGM cation diffusion facilitator family transporter BT10792_10665 ENOG4105CAQ asparagine synthetase BT10792_10685 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BT10792_10695 ENOG4105CVJ phosphoglycerate mutase BT10792_10750 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BT10792_10825 ENOG4105CPU Monooxygenase BT10792_10830 ENOG4105KTQ flagellar basal-body rod protein BT10792_10840 ENOG4105D7B Flagellar biosynthesis protein flha BT10792_10855 ENOG4105VS8 Flagellar biosynthetic protein fliq BT10792_10860 ENOG4105CN7 Flagellar biosynthetic protein FliP BT10792_10870 ENOG4105DD5 Flagellar motor switch protein BT10792_10885 ENOG4105E4C Lytic transglycosylase catalytic BT10792_10890 ENOG4105I03 Flagellin BT10792_10895 ENOG4105I03 Flagellin BT10792_10905 ENOG4107R88 Chemotaxis protein (CheV) BT10792_10920 ENOG4105BZE flagellar hook protein, FlgE BT10792_10950 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BT10792_10960 ENOG41075Z6 flagellar hook-basal body complex protein fliE BT10792_10970 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BT10792_11030 ENOG4105DD5 Flagellar motor switch protein BT10792_11035 ENOG4105CBS Chea signal transduction histidine kinase BT10792_11040 ENOG4107YTP response regulator receiver protein BT10792_11050 ENOG4107R0U MotA TolQ exbB proton channel BT10792_11060 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BT10792_11150 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BT10792_11250 ENOG4105CPK Glycosyl transferase (Group 1 BT10792_11280 ENOG4105HTX biosynthesis protein BT10792_11335 ENOG4105KHC sulfurtransferase BT10792_11345 ENOG4108W0I acetyltransferase BT10792_11365 ENOG4105DHF Membrane BT10792_11370 ENOG4105C2W permease BT10792_11380 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BT10792_11405 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BT10792_11420 ENOG4106F55 Protein of unknown function (DUF1273) BT10792_11490 ENOG4105YAC BT10792_11510 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BT10792_11535 ENOG4105CPK Glycosyl transferase (Group 1 BT10792_11540 ENOG4105FJR Lmbe family BT10792_11555 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BT10792_11560 ENOG4108JYZ YitT family BT10792_11595 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BT10792_11600 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BT10792_11615 ENOG41068YB TPR repeat-containing protein BT10792_11635 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BT10792_11650 ENOG4105XXQ heptaprenyl diphosphate synthase component I BT10792_11665 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BT10792_11695 ENOG41065D1 BT10792_11700 ENOG4105S2F BT10792_11735 ENOG4107RB3 L-asparaginase BT10792_11740 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BT10792_11765 ENOG4108S6Z Negative regulator of genetic competence BT10792_11770 ENOG4108XDN Transcriptional regulator BT10792_11775 ENOG4107RGJ metallophosphoesterase BT10792_11785 ENOG4105I7S Abortive infection protein BT10792_11790 ENOG4105C9U ATP-dependent DNA helicase RecQ BT10792_11805 ENOG4108SAX Membrane BT10792_11840 ENOG4107TWT Cytochrome c biogenesis protein BT10792_11845 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BT10792_11860 ENOG4108JIC nucleoside recognition domain protein BT10792_11865 ENOG4105DZ1 carboxypeptidase BT10792_11870 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BT10792_11925 ENOG4105BZU Histidine kinase BT10792_11950 ENOG4107GRR phosphate transport regulator BT10792_11955 ENOG4105CJ3 phosphate transporter BT10792_12005 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BT10792_12030 ENOG4105ENE Histidine kinase BT10792_12080 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BT10792_12090 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BT10792_12100 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BT10792_12105 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BT10792_12125 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BT10792_12135 ENOG4105E0M Sulfatase BT10792_12140 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BT10792_12180 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BT10792_12185 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BT10792_12190 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BT10792_12235 ENOG4105C7K acetolactate synthase BT10792_12240 ENOG4105CM2 brancheD-chain amino acid aminotransferase BT10792_12270 ENOG4105KBJ sporulation protein ytfj BT10792_12275 ENOG41063Y9 BT10792_12280 ENOG4105CZN Potassium uptake protein BT10792_12310 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BT10792_12355 ENOG4105NQC Flavodoxin BT10792_12395 ENOG4105EA8 2-Nitropropane dioxygenase BT10792_12400 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BT10792_12440 ENOG4105CJ1 ABC, transporter BT10792_12450 ENOG4105CZV ABC transporter BT10792_12470 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BT10792_12475 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BT10792_12525 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BT10792_12530 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BT10792_12535 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BT10792_12540 ENOG4105BZU Histidine kinase BT10792_12560 ENOG41090MY MarR family Transcriptional regulator BT10792_12710 ENOG4106A3R peptidase BT10792_12730 ENOG4105JXH GntR family transcriptional regulator BT10792_12740 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_12755 ENOG4105CQB FAD linked oxidase domain protein BT10792_12765 ENOG4105K4I Scp-like extracellular BT10792_12775 ENOG4108YBP pseudouridine synthase BT10792_12785 ENOG4105EYF MMPL domain protein BT10792_12795 ENOG4107RUE extracellular solute-binding protein family 1 BT10792_12800 ENOG4105D38 putrescine abc transporter BT10792_12805 ENOG4105F38 ABC transporter, permease BT10792_12810 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BT10792_12850 ENOG4105VFR signal peptidase BT10792_12855 ENOG4105DZ1 carboxypeptidase BT10792_12930 ENOG4105VZ8 Transcriptional regulator BT10792_12940 ENOG4105C7S Dehydrogenase BT10792_12960 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BT10792_12990 ENOG4105T65 Membrane-associated protein BT10792_13030 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BT10792_13035 ENOG4105DK0 Indole-3-glycerol phosphate synthase BT10792_13045 ENOG4105DDQ anthranilate synthase BT10792_13050 ENOG4105CRQ synthase (Component I) BT10792_13060 ENOG4105CK7 Sodium proline symporter BT10792_13180 ENOG4107TVC Glycosyl transferase, family 2 BT10792_13200 ENOG4105K64 Glycosyl transferase, family 2 BT10792_13230 ENOG4105EMS pseudouridine synthase BT10792_13235 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BT10792_13245 ENOG4106EFP UPF0738 protein BT10792_13250 ENOG4105MIX Adenylate cyclase BT10792_13255 ENOG4108Z18 K06886 hemoglobin BT10792_13280 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BT10792_13320 ENOG4105UQX Mate efflux family protein BT10792_13325 ENOG4108JQ7 (ABC) transporter BT10792_13335 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BT10792_13340 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BT10792_13360 ENOG4105C31 Tryptophanyl-tRNA synthetase BT10792_13375 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BT10792_13380 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BT10792_13405 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BT10792_13420 ENOG4108KP7 hydrolase BT10792_13430 ENOG41073B9 BT10792_13435 ENOG4107AYK membrAne BT10792_13450 ENOG4105QNR S1 RNA binding domain protein BT10792_13485 ENOG4105CH6 catalase BT10792_13495 ENOG4105CAQ asparagine synthetase BT10792_13520 ENOG4105ERH Fumarylacetoacetate hydrolase BT10792_13560 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BT10792_13605 ENOG4105VEQ Cold shock protein BT10792_13635 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) BT10792_13695 ENOG41085W3 Transposase BT10792_13700 ENOG41086D8 Transcriptional regulator BT10792_13705 ENOG4108AEY RNA polymerase sigma factor BT10792_13715 ENOG4107TVP HD domain protein BT10792_13720 ENOG4107RN3 metallophosphoesterase BT10792_13730 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BT10792_13735 ENOG4108IJ6 ABC transporter BT10792_13745 ENOG4108I5D sulfate abc transporter BT10792_13775 ENOG4108RQ5 Beta-lactamase domain-containing protein BT10792_13780 ENOG4106AXD BT10792_13795 ENOG4108MK9 spermidine N(1)-acetyltransferase BT10792_13815 ENOG4105ECB domain protein BT10792_13830 ENOG4105NA0 Transcriptional regulator BT10792_13860 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BT10792_13870 ENOG4105BZ4 penicillin-binding protein BT10792_13875 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BT10792_13880 ENOG4105CKV Membrane BT10792_13885 ENOG410905X membrane-flanked domain protein BT10792_13935 ENOG4105CKV Membrane BT10792_13940 ENOG410905X membrane-flanked domain protein BT10792_14010 ENOG4105K59 histidine triad (HIT) protein BT10792_14100 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BT10792_14105 ENOG41067QW Transcriptional regulator BT10792_14110 ENOG4105F0F Oxalate decarboxylase BT10792_14135 ENOG4108MUZ hydrolase BT10792_14165 ENOG410829K Lysine exporter protein (Lyse ygga) BT10792_14185 ENOG4106D4I domain protein BT10792_14190 ENOG4107VRP DNA repair exonuclease BT10792_14260 ENOG4105BZU Histidine kinase BT10792_14265 ENOG4105BZU Histidine kinase BT10792_14270 ENOG4108MJI response regulator BT10792_14280 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BT10792_14290 ENOG4105WN5 stage II sporulation protein BT10792_14340 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BT10792_14435 ENOG4105CMT Dihydroxyacetone kinase BT10792_14460 ENOG4105WAB arsR family transcriptional regulator BT10792_14465 ENOG4105F27 Major Facilitator BT10792_14545 ENOG4105F6J Alpha beta hydrolase fold BT10792_14580 ENOG4105C0R drug resistance transporter emrb qaca subfamily BT10792_14620 ENOG4105CDU Replicative dna helicase BT10792_14635 ENOG4105M6F mutator MutT protein BT10792_14655 ENOG4105CSH Transporter BT10792_14720 ENOG4108JQ7 (ABC) transporter BT10792_14725 ENOG4105C3U ABC transporter BT10792_14745 ENOG4105CIF Ornithine Cyclodeaminase BT10792_14750 ENOG4105CTU Proline racemase BT10792_14770 ENOG4105DER m42 family BT10792_14790 ENOG4105CGU Enoyl-CoA hydratase BT10792_14820 ENOG4105CHH sulfate transporter BT10792_14870 ENOG4107FQX Alpha-acetolactate decarboxylase BT10792_14910 ENOG410839P BT10792_14925 ENOG4105CDA abc transporter atp-binding protein BT10792_14930 ENOG4105DRP amino acid AbC transporter BT10792_14945 ENOG4105BZ1 (ABC) transporter BT10792_14995 ENOG4105CH6 catalase BT10792_15000 ENOG4107RKG DJ-1/PfpI family BT10792_15015 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BT10792_15050 ENOG4105KPY Small multidrug resistance protein BT10792_15060 ENOG4105UBK short-chain dehydrogenase reductase BT10792_15065 ENOG4105CH7 arginosuccinase BT10792_15070 ENOG4108YXU transcriptional regulator AsnC family BT10792_15110 ENOG4106KNT transcriptional regulator BT10792_15120 ENOG4107RWR Sodium hydrogen exchanger BT10792_15165 ENOG4107T5V SNARE associated Golgi BT10792_15200 ENOG4105WEF catalase BT10792_15230 ENOG4105C19 ABC transporter BT10792_15240 ENOG41069ER domain protein BT10792_15260 ENOG4105VZJ PTS System BT10792_15265 ENOG4105VCP PTS System BT10792_15325 ENOG41085GJ domain protein BT10792_15330 ENOG4105VFE sira family BT10792_15335 ENOG4107TPS domain protein BT10792_15345 ENOG4105XTG Pfam:DUF156 BT10792_15350 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BT10792_15370 ENOG4105J4Q Transcriptional regulator BT10792_15380 ENOG4105ED1 spovr family BT10792_15385 ENOG4107Y03 Nitroreductase BT10792_15430 ENOG4105K63 Thioredoxin BT10792_15465 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BT10792_15475 ENOG4105C7N Xanthine uracil vitamin C permease BT10792_15490 ENOG4108INS Transcriptional regulator BT10792_15505 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) BT10792_15535 ENOG4105DWF phosphomethylpyrimidine kinase BT10792_15540 ENOG4105D06 uba thif-type nad fad binding protein BT10792_15560 ENOG4108VEU Thiamine monophosphate synthase BT10792_15570 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BT10792_15580 ENOG4105ETU transcriptional activator (TenA BT10792_15605 ENOG41080XQ Signal transduction protein with cbs domains BT10792_15750 ENOG4105C8U phosphate abc transporter BT10792_15755 ENOG4105CVA phosphate BT10792_15760 ENOG4105CE1 Ferrous iron transport protein b BT10792_15810 ENOG4105E1V na solute symporter BT10792_15815 ENOG4106CAD Protein of unknown function (DUF3311) BT10792_15835 ENOG4105E2S oxidase) subunit II BT10792_15840 ENOG4105BZ9 Cytochrome C oxidase, subunit I BT10792_15845 ENOG4105CCU oxidase (Subunit III) BT10792_15880 ENOG4105C7N Xanthine uracil vitamin C permease BT10792_15885 ENOG4105C85 amino acid BT10792_15920 ENOG4107D63 BT10792_15930 ENOG41069ER domain protein BT10792_15940 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BT10792_16000 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BT10792_16095 ENOG4108C33 Resolvase BT10792_16130 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BT10792_16175 ENOG4108PNI recT protein BT10792_16180 ENOG4108NF7 phage-type endonuclease BT10792_16220 ENOG4108IMY Transcriptional regulator BT10792_16235 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) BT10792_16270 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BT10792_16275 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BT10792_16295 ENOG4108RVA ribokinase BT10792_16310 ENOG41067TZ transcriptional regulator, MarR family BT10792_16315 ENOG4105CXY transporter BT10792_16325 ENOG4108JQ7 (ABC) transporter BT10792_16330 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BT10792_16350 ENOG41068KF Universal stress protein BT10792_16355 ENOG4105CHH sulfate transporter BT10792_16390 ENOG4105NAE bifunctional deaminase-reductase domain protein BT10792_16395 ENOG4105D29 Helix-turn-helix type 11 domain protein BT10792_16405 ENOG4105GFR rna polymerase sigma factor BT10792_16420 ENOG4108IQI permease BT10792_16425 ENOG4105DRP amino acid AbC transporter BT10792_16430 ENOG4105EAD ABC transporter BT10792_16435 ENOG4105CT1 (ABC) transporter BT10792_16440 ENOG4105CDA abc transporter atp-binding protein BT10792_16455 ENOG4105CRN Aminoglycoside phosphotransferase BT10792_16465 ENOG4105E1K spore germination protein BT10792_16490 ENOG4105CG3 alpha amylase, catalytic region BT10792_16495 ENOG4105C5Y PTS System BT10792_16530 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BT10792_16545 ENOG4105EXW epimerase dehydratase BT10792_16555 ENOG4105EKQ RNA-directed DNA polymerase BT10792_16570 ENOG4105E0A ABC, transporter BT10792_16580 ENOG4105DQ5 transport system permease protein BT10792_16590 ENOG4105DUX Transporter BT10792_16610 ENOG4105DAA L-lactate BT10792_16625 ENOG41085W3 Transposase BT10792_16630 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BT10792_16635 ENOG4105D9N nucleoside BT10792_16640 ENOG4108KGH TRANSCRIPTIONal BT10792_16685 ENOG4105DAP Nicotinate phosphoribosyltransferase BT10792_16690 ENOG4105C59 p-type ATPase BT10792_16720 ENOG4108JB9 formate dehydrogenase BT10792_16725 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BT10792_16760 ENOG4108UZ3 Transporter BT10792_16770 ENOG4105C6K Malic enzyme BT10792_16805 ENOG4105US7 Histidine kinase BT10792_16810 ENOG4108STX response regulator BT10792_16815 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BT10792_16825 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BT10792_16835 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BT10792_16865 ENOG4105D4T Citrate transporter BT10792_16870 ENOG4105D4T Citrate transporter BT10792_16880 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BT10792_16890 ENOG4105DZ6 Band 7 protein BT10792_16905 ENOG4105C94 Transporter BT10792_16940 ENOG4105BZU Histidine kinase BT10792_16945 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BT10792_16970 ENOG4108JQC penicillin-binding protein 1A BT10792_17095 ENOG4105G5W regulator Fur family BT10792_17100 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BT10792_17120 ENOG4108IUW ABC transporter BT10792_17135 ENOG4107NBY Membrane BT10792_17140 ENOG4105BZ1 (ABC) transporter BT10792_17160 ENOG4106BXE BT10792_17165 ENOG4105CEN a g-specific adenine glycosylase BT10792_17170 ENOG41067AE Membrane-bound metal-dependent hydrolase BT10792_17200 ENOG4105ECP epimerase BT10792_17205 ENOG4105CI2 imidazolone-5-propionate hydrolase BT10792_17225 ENOG4105F1A Pyruvate formate-lyase BT10792_17240 ENOG4105CKK Glycosyl transferase, family 2 BT10792_17255 ENOG4107R51 Glycosyl transferase, family 2 BT10792_17270 ENOG4108A04 Beta-lactamase BT10792_17310 ENOG4108IQI permease BT10792_17365 ENOG4105UPD Calcium Proton BT10792_17385 ENOG4107ZTW SNARE associated Golgi BT10792_17405 ENOG4108IPJ Membrane BT10792_17410 ENOG4105C59 p-type ATPase BT10792_17420 ENOG4107U9T Pfam:Ribonuclease_BN BT10792_17430 ENOG4105KJF protein tyrosine phosphatase BT10792_17435 ENOG41068PA UPF0435 protein BT10792_17455 ENOG4107TS3 membrane protein, TerC BT10792_17460 ENOG4106FN3 tellurium resistance protein BT10792_17465 ENOG4106FN3 tellurium resistance protein BT10792_17470 ENOG4108N0M stress protein BT10792_17485 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BT10792_17500 ENOG4105DEU major facilitator superfamily BT10792_17560 ENOG4105D2X ABC transporter substrate-binding protein BT10792_17565 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BT10792_17615 ENOG4105CI1 PTS System BT10792_17625 ENOG4105DNP FAD linked oxidase domain protein BT10792_17635 ENOG4108W63 CRP FNR family transcriptional regulator BT10792_17680 ENOG4105E5Q amino acid AbC transporter BT10792_17720 ENOG4105BZU Histidine kinase BT10792_17740 ENOG4106UIA BT10792_17745 ENOG4106UIA BT10792_17765 ENOG4105CAY ferredoxin--nadp reductase BT10792_17775 ENOG4108V5C ABC transporter BT10792_17785 ENOG4105EHG Permease protein BT10792_17790 ENOG4107W7X Aldolase BT10792_17795 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BT10792_17800 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BT10792_17805 ENOG4105D3R alkyl hydroperoxide reductase BT10792_17830 ENOG4105DFD Na H antiporter BT10792_17855 ENOG4108W15 Protein of unknown function (DUF1456) BT10792_17865 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BT10792_17870 ENOG4105D9N nucleoside BT10792_17895 ENOG4105KPY Small multidrug resistance protein BT10792_17900 ENOG4105C26 Dehydrogenase BT10792_17910 ENOG4108JPW Aminotransferase BT10792_17920 ENOG4105CBD Diacylglycerol kinase BT10792_17940 ENOG4107I77 yiaA/B two helix domain BT10792_17945 ENOG410834F Transcriptional regulator BT10792_17965 ENOG4105D01 (LipO)protein BT10792_17970 ENOG4108UMI ABC transporter, permease BT10792_17975 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BT10792_17980 ENOG4108W2Y isochorismatase BT10792_18040 ENOG4105C12 Phosphoribosylglycinamide synthetase BT10792_18050 ENOG4108V3E phosphoribosylglycinamide formyltransferase BT10792_18075 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BT10792_18095 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BT10792_18120 ENOG4105SX7 Transporter BT10792_18215 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BT10792_18235 ENOG4107ZXU DSBA oxidoreductase BT10792_18260 ENOG4105BZU Histidine kinase BT10792_18270 ENOG4105C7N Xanthine uracil vitamin C permease BT10792_18300 ENOG4108TYN CAAX amino terminal protease family protein BT10792_18315 ENOG4105C5H ABC transporter BT10792_18325 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BT10792_18330 ENOG410801F ribosomal-protein-alanine acetyltransferase BT10792_18335 ENOG41072GX Peptidase M22 Glycoprotease BT10792_18340 ENOG4105K8N protein family UPF0079, ATPase BT10792_18445 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BT10792_18455 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BT10792_18520 ENOG4105ERH Fumarylacetoacetate hydrolase BT10792_18525 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BT10792_18555 ENOG410667J hydrolase BT10792_18560 ENOG4108JQ7 (ABC) transporter BT10792_18565 ENOG4105C3U ABC transporter BT10792_18570 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BT10792_18595 ENOG4105C5H ABC transporter BT10792_18620 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BT10792_18640 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BT10792_18665 ENOG4105F6E Acyl-transferase BT10792_18685 ENOG4105EGI Transcriptional regulator BT10792_18705 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BT10792_18710 ENOG4105E0C molybdate abc transporter BT10792_18745 ENOG4108J59 Extracellular solute-binding protein, family 5 BT10792_18765 ENOG4108JQ7 (ABC) transporter BT10792_18770 ENOG4105C3U ABC transporter BT10792_18775 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BT10792_18780 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BT10792_18800 ENOG4105C2C drug resistance transporter, Bcr CflA BT10792_18840 ENOG4108UMI ABC transporter, permease BT10792_18875 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BT10792_18895 ENOG4105C8B TIGR00159 family BT10792_18995 ENOG4105D1F ATP-binding protein BT10792_19025 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BT10792_19030 ENOG4108JJB ABC transporter BT10792_19035 ENOG4108JJB ABC transporter BT10792_19060 ENOG41067V7 50S ribosomal protein L36 BT10792_19070 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BT10792_19080 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BT10792_19105 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BT10792_19215 ENOG4105XPM ribosomal protein BT10792_19220 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BT10792_19230 ENOG4107Y49 methyltransferase BT10792_19235 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BT10792_19255 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BT10792_19270 ENOG4105QIV RNA polymerase BT10792_19280 ENOG4105C2N RNA methyltransferase TrmH family group 3 BT10792_19295 ENOG4105D7W serine acetyltransferase BT10792_19315 ENOG4105CTP PilT protein domain protein BT10792_19430 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BT10792_19440 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BT10792_19445 ENOG4105KRF dihydroneopterin aldolase BT10792_19450 ENOG4105EEI dihydropteroate synthase BT10792_19460 ENOG4105DDQ anthranilate synthase BT10792_19470 ENOG4105C6T cysteine synthase BT10792_19485 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BT10792_19490 ENOG4108UGV hypoxanthine phosphoribosyltransferase BT10792_19515 ENOG41060GV RNA binding s1 domain protein BT10792_19530 ENOG4105VYY sporulation protein yabp BT10792_19535 ENOG41082I2 s4 domain protein BT10792_19540 ENOG4108IY2 MazG family BT10792_19550 ENOG4108M14 stage v sporulation protein t BT10792_19555 ENOG4108JA2 transcriptioN-repair coupling factor BT10792_19565 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BT10792_19570 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BT10792_19585 ENOG4105KME endoribonuclease L-psp BT10792_19595 ENOG4105DFT pur operon repressor BT10792_19610 ENOG4105W42 Veg protein BT10792_19615 ENOG4105XFA sporulation peptidase YabG BT10792_19625 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BT10792_19630 ENOG4105F8V Hydrolase, tatD family BT10792_19640 ENOG4105KRN Transcriptional regulator, abrb family BT10792_19655 ENOG41060K3 Methyltransferase BT10792_19665 ENOG4105MA4 psp1 domain protein BT10792_19680 ENOG4105CXN decarboxylase BT10792_19715 ENOG41067KS pro-sigma K processing BT10792_19740 ENOG4105C6E dna polymerase iii BT10792_19760 ENOG4105GTG Isochorismatase BT10792_19770 ENOG4105ZMH deoxynucleoside kinase BT10792_19805 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BT10792_19840 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BT10792_19855 ENOG410848D S4 domain protein YaaA BT10792_19860 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BT10792_19880 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BT10792_19890 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BT10792_19895 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BT10792_19910 ENOG4107QJE Chromosome Partitioning Protein BT10792_19920 ENOG4108ZDA Sporulation protein YyaC BT10792_19925 ENOG4105D8X mechanosensitive ion channel BT10792_19930 ENOG4105VDK protein, conserved in bacteria BT10792_19945 ENOG4108UUM single-stranded DNA-binding protein BT10792_19960 ENOG4105BZR domain protein BT10792_19970 ENOG4105CDU Replicative dna helicase BT10792_19975 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BT10792_20000 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_20005 ENOG4105BZU Histidine kinase BT10792_20025 ENOG4105C0H protease BT10792_20060 ENOG4105C1J atp-dependent rna helicase BT10792_20065 ENOG4105C1J atp-dependent rna helicase BT10792_20075 ENOG4108UT2 hemolysin iii BT10792_20080 ENOG4105CMR udp-glucose 4-epimerase BT10792_20090 ENOG4105IW1 AmiS UreI transporter BT10792_20100 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BT10792_20120 ENOG4107RGD Major Facilitator superfamily BT10792_20130 ENOG4108NEV two component transcriptional regulator, LytTR family BT10792_20145 ENOG4106F5Q Membrane BT10792_20150 ENOG4105E0X reductase BT10792_20160 ENOG41067SE Tetr family transcriptional regulator BT10792_20180 ENOG4105CKK Glycosyl transferase, family 2 BT10792_20185 ENOG4105EJV Membrane BT10792_20210 ENOG4108S4H thioesterase Superfamily protein BT10792_20220 ENOG4106YBV Methyl-accepting chemotaxis BT10792_20225 ENOG4105EN6 Membrane BT10792_20245 ENOG4105CG5 Glycosyl transferase (Group 1 BT10792_20260 ENOG41079KZ Major Facilitator Superfamily BT10792_20265 ENOG4105DY9 regulatoR BT10792_20270 ENOG4105D22 carbon starvation protein BT10792_20275 ENOG4105VCD cytoplasmic protein BT10792_20285 ENOG4105DWF phosphomethylpyrimidine kinase BT10792_20290 ENOG4105BZU Histidine kinase BT10792_20305 ENOG4108Y4K DNA-binding transcriptional activator BT10792_20330 ENOG4105D6E homoserine dehydrogenase BT10792_20355 ENOG4108TU7 Inherit from COG: (ABC) transporter BT10792_20365 ENOG4105VCH membrane BT10792_20370 ENOG410667J hydrolase BT10792_20380 ENOG4107SVH Potassium channel protein BT10792_20400 ENOG4108VKI Cell wall hydrolase BT10792_20410 ENOG4107UEZ chlorite dismutase BT10792_20415 ENOG4108IJ2 phosphate acetyltransferase BT10792_20420 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BT10792_20425 ENOG4108VCI transcription factor, rsfa family BT10792_20435 ENOG4105DQ5 transport system permease protein BT10792_20440 ENOG4105EHG Permease protein BT10792_20445 ENOG4105E0A ABC, transporter BT10792_20450 ENOG4108MES Periplasmic binding protein BT10792_20455 ENOG4105DCI Phosphohydrolase BT10792_20460 ENOG41069HH 4-oxalocrotonate tautomerase BT10792_20465 ENOG4108Z4T Peptidase M50 BT10792_20470 ENOG4108XFG YwhD family BT10792_20475 ENOG4105BZ4 penicillin-binding protein BT10792_20480 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BT10792_20485 ENOG4107SWG transcriptional regulator MERR family BT10792_20490 ENOG4105DXB Major Facilitator superfamily BT10792_20500 ENOG4105CYW agmatinase BT10792_20525 ENOG410684U Domain of unknown function (DUF1934) BT10792_20540 ENOG4105EMN RNA polymerase sigma factor BT10792_20570 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BT10792_20580 ENOG4105KCT ABC transporter BT10792_20585 ENOG4105BZU Histidine kinase BT10792_20625 ENOG4105DF6 Fe-S oxidoreductase BT10792_20645 ENOG4105C1G acyl-Coa dehydrogenase BT10792_20680 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BT10792_20690 ENOG4105CBT Fructose-1,6-bisphosphatase BT10792_20715 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BT10792_20735 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BT10792_20755 ENOG4107XC4 flavin reductase domain protein, FMN-binding BT10792_20760 ENOG4108VGI doxx family BT10792_20780 ENOG4108YZG isomerase BT10792_20785 ENOG4108UIC UPF0340 protein BT10792_20820 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BT10792_20870 ENOG4105BZU Histidine kinase BT10792_20880 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BT10792_20890 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BT10792_20895 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BT10792_20920 ENOG4105D65 subunit l BT10792_20925 ENOG4105C8S subunit m BT10792_20935 ENOG4106778 Protein of unknown function (DUF1146) BT10792_20955 ENOG4105DY9 regulatoR BT10792_20980 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BT10792_20995 ENOG4107YJ4 chain length determinant protein BT10792_21005 ENOG4107YJ4 chain length determinant protein BT10792_21010 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BT10792_21015 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BT10792_21020 ENOG4105D3Q Sugar transferase BT10792_21065 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BT10792_21085 ENOG4105CMR udp-glucose 4-epimerase BT10792_21100 ENOG4105DG6 mannose-6-phosphate isomerase BT10792_21105 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_21110 ENOG4105BZU Histidine kinase BT10792_21125 ENOG4105CXY transporter BT10792_21145 ENOG4105C19 ABC transporter BT10792_21150 ENOG4107RBB ABC transporter, permease BT10792_21160 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BT10792_21190 ENOG41085W3 Transposase BT10792_21235 ENOG4105C94 Transporter BT10792_21245 ENOG4107R8N Glycosyl transferase, family 2 BT10792_21275 ENOG4105E0M Sulfatase BT10792_21295 ENOG4105DAA L-lactate BT10792_21380 ENOG4105VZJ PTS System BT10792_21390 ENOG4105VCP PTS System BT10792_21400 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BT10792_21410 ENOG4105CK1 PTS System BT10792_21415 ENOG4105VCP PTS System BT10792_21450 ENOG4105ESV Glycosyl transferase, family 4 BT10792_21460 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BT10792_21470 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BT10792_21485 ENOG4105KVH Transcriptional regulator BT10792_21510 ENOG4105VEQ Cold shock protein BT10792_21515 ENOG4105MS2 ribosomal subunit Interface protein BT10792_21545 ENOG4105CAK Cell division ATP-binding protein ftsE BT10792_21550 ENOG4105CRP Part of the ABC transporter FtsEX involved in BT10792_21555 ENOG4105CN1 protease BT10792_21580 ENOG4105C5H ABC transporter BT10792_21585 ENOG4108WS4 fmn reductase BT10792_21595 ENOG4105DUM transcriptional regulator, lysR family BT10792_21635 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BT10792_21645 ENOG41086DT Membrane protein of unknown function BT10792_21665 ENOG4108S4C acetyltransferase BT10792_21675 ENOG4105C3M thioredoxin reductase BT10792_21695 ENOG4105CHW UPF0052 protein BT10792_21705 ENOG4105KRI phosphocarrier protein (HPr BT10792_21710 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BT10792_21715 ENOG4108QY0 Membrane BT10792_21730 ENOG4105CZ3 stage V sporulation protein ad BT10792_21735 ENOG41090VF Stage v sporulation protein ac BT10792_21755 ENOG4108W5X Transcriptional Regulator, LuxR family BT10792_21760 ENOG4105BZU Histidine kinase BT10792_21820 ENOG41067MG lrgb family BT10792_21825 ENOG4105XZU Preprotein translocase, subunit SecG BT10792_21835 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BT10792_21870 ENOG4105CM4 permease protein BT10792_21875 ENOG4108IPW abc transporter atp-binding protein BT10792_21910 ENOG4108W2Y isochorismatase BT10792_21920 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BT10792_21925 ENOG4108MK9 spermidine N(1)-acetyltransferase BT10792_21940 ENOG4105WMR Protein CrcB homolog BT10792_21945 ENOG4105WMR Protein CrcB homolog BT10792_21975 ENOG4105D4A Cell wall formation (By similarity) BT10792_21980 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BT10792_21995 ENOG4105KVH Transcriptional regulator BT10792_22000 ENOG4105F27 Major Facilitator BT10792_22005 ENOG4105CV8 reductase BT10792_22025 ENOG4108RYK Nad-dependent epimerase dehydratase BT10792_22040 ENOG4105D9N nucleoside BT10792_22045 ENOG4105D9N nucleoside BT10792_22060 ENOG41090A1 ferritin BT10792_22070 ENOG4108URH decarboxylase BT10792_22090 ENOG4108RMU ferritin dps family protein BT10792_22110 ENOG4107S91 Sodium hydrogen exchanger BT10792_22115 ENOG4107T5V SNARE associated Golgi BT10792_22130 ENOG4105C2I pirin domain protein BT10792_22135 ENOG4105D4Y metalloprotease BT10792_22140 ENOG4105VG1 fes assembly suf system protein BT10792_22145 ENOG4105C8Q Methyl-accepting chemotaxis BT10792_22150 ENOG4105C8Q Methyl-accepting chemotaxis BT10792_22175 ENOG4105BZU Histidine kinase BT10792_22180 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_22195 ENOG4107ZTW SNARE associated Golgi BT10792_22235 ENOG4107AYK membrAne BT10792_22245 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BT10792_22260 ENOG4107R7I amino acid BT10792_22265 ENOG4108SUT Major Facilitator Superfamily BT10792_22300 ENOG4105DZ1 carboxypeptidase BT10792_22315 ENOG4105CHU acetyl-coa acetyltransferase BT10792_22320 ENOG4105C1G acyl-Coa dehydrogenase BT10792_22350 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BT10792_22390 ENOG41080E8 Transcriptional regulator, Spx MgsR family BT10792_22415 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BT10792_22420 ENOG4108UMI ABC transporter, permease BT10792_22430 ENOG4105D01 (LipO)protein BT10792_22435 ENOG4105C3K feS assembly ATPase SufC BT10792_22440 ENOG4105JRK feS assembly protein SufD BT10792_22445 ENOG4105C9B Cysteine desulfurase BT10792_22450 ENOG4108UNV SUF system FeS assembly protein, NifU family BT10792_22455 ENOG4105DIW FeS assembly protein SUFB BT10792_22460 ENOG4107R8B 5'-nucleotidase BT10792_22465 ENOG4105KZD Domain of unknown function (DUF1805) BT10792_22470 ENOG4108YTE sporulation protein YunB BT10792_22500 ENOG41090T1 Membrane BT10792_22510 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BT10792_22515 ENOG4105MMD transcriptional regulator BT10792_22555 ENOG4105D4U had-superfamily hydrolase, subfamily iia BT10792_22565 ENOG4105DYS nad(p)h dehydrogenase (quinone) BT10792_22600 ENOG4108W5N phosphatidylglycerophosphatase a BT10792_22620 ENOG41083MR nifu domain-containing protein BT10792_22650 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BT10792_22655 ENOG4105C4B ABC transporter, permease BT10792_22680 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BT10792_22700 ENOG4108VQJ O-methyltransferase BT10792_22775 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BT10792_22925 ENOG4105XSJ toxin secretion phage lysis holin BT10792_22980 ENOG4105EWC Purine nucleoside phosphorylase BT10792_23015 ENOG4105CEP NADH dehydrogenase BT10792_23030 ENOG41069ER domain protein BT10792_23045 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) BT10792_23075 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BT10792_23090 ENOG4105KA0 thioesterase Superfamily protein BT10792_23140 ENOG4105C87 Aminotransferase class I and II BT10792_23150 ENOG4108MUZ hydrolase BT10792_23155 ENOG4105C5I Dehydrogenase BT10792_23160 ENOG4108ZB6 transcriptional regulator AsnC family BT10792_23165 ENOG4105CHM Aminotransferase BT10792_23175 ENOG4105WG9 Conserved Protein BT10792_23195 ENOG4107PBV potassium channel BT10792_23200 ENOG4105KT7 mgtC SapB transporter BT10792_23365 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BT10792_23410 ENOG4105VEQ Cold shock protein BT10792_23420 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BT10792_23425 ENOG4105E4F Isochorismate synthase BT10792_23435 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BT10792_23445 ENOG4105CEY Amp-dependent synthetase and ligase BT10792_23450 ENOG4105DTQ mandelate racemase muconate lactonizing BT10792_23495 ENOG4105FDP GntR family transcriptional regulator BT10792_23505 ENOG4105C6Z Gluconate BT10792_23555 ENOG41082BM Transcriptional regulator, arsr family BT10792_23570 ENOG41086D8 Transcriptional regulator BT10792_23575 ENOG4105C19 ABC transporter BT10792_23605 ENOG4105C19 ABC transporter BT10792_23620 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BT10792_23650 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BT10792_23660 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BT10792_23720 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BT10792_23750 ENOG410839T multidrug resistance protein BT10792_23815 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BT10792_23825 ENOG4105D2X ABC transporter substrate-binding protein BT10792_23845 ENOG4107T7U Sulfatase BT10792_23850 ENOG4107S9D Alpha beta hydrolase BT10792_23855 ENOG4105CH6 catalase BT10792_23860 ENOG4105BZU Histidine kinase BT10792_23865 ENOG4105BZU Histidine kinase BT10792_23960 ENOG4105BZF Glycosyl transferase (Group 1 BT10792_23965 ENOG4105YVM Phosphoesterase, PA-phosphatase related BT10792_23970 ENOG4108Z0R Transferase BT10792_23975 ENOG4105E8V Alpha Beta Hydrolase Fold protein BT10792_24020 ENOG4105N5T Radical SAM Protein BT10792_24040 ENOG4105D7V transposase BT10792_24050 ENOG4105C19 ABC transporter BT10792_24065 ENOG4105NCW Trka-c domain protein BT10792_24070 ENOG4107S91 Sodium hydrogen exchanger BT10792_24075 ENOG410605W Major Facilitator BT10792_24080 ENOG4105C8T Leucyl-tRNA synthetase BT10792_24105 ENOG4108B31 Spore germination protein BT10792_24130 ENOG41085GJ domain protein BT10792_24160 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BT10792_24165 ENOG4105D06 uba thif-type nad fad binding protein BT10792_24180 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BT10792_24185 ENOG4108ZAF Molybdopterin BT10792_24270 ENOG4105YW5 deoR family transcriptional regulator BT10792_24290 ENOG4108V15 phosphotransferase enzyme family BT10792_24305 ENOG4105C8F Beta-lactamase domain protein BT10792_24335 ENOG4108VDD TRNA binding domain protein BT10792_24370 ENOG4108IPJ Membrane BT10792_24415 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BT10792_24420 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BT10792_24425 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BT10792_24435 ENOG4105ETE Transcriptional regulator (LacI family BT10792_24475 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BT10792_24485 ENOG4106HB6 Alpha beta hydrolase BT10792_24490 ENOG4105DGU Histone deacetylase BT10792_24495 ENOG4105W87 Cbs domain BT10792_24500 ENOG4105F1V Acetoin utilization protein BT10792_24510 ENOG4108UW5 maltose o-acetyltransferase BT10792_24520 ENOG4105EMN RNA polymerase sigma factor BT10792_24555 ENOG4105C28 cystathionine BT10792_24575 ENOG4105RQF LysR family Transcriptional regulator BT10792_24610 ENOG4105EFZ amidohydrolase BT10792_24625 ENOG4105KBJ sporulation protein ytfj BT10792_24630 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BT10792_24640 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BT10792_24660 ENOG4108JYZ YitT family BT10792_24710 ENOG4107YZX Universal stress protein BT10792_24730 ENOG41082W1 Cupin 2, conserved barrel domain protein BT10792_24735 ENOG4105Z7P Acetyltransferase (GNAT) family BT10792_24775 ENOG4105DC7 peptidase M24 BT10792_24805 ENOG4105SFS phosphoesterase RecJ domain protein BT10792_24825 ENOG4105C6K Malic enzyme BT10792_24830 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BT10792_24855 ENOG4105FS0 cytoplasmic membrane protein BT10792_24860 ENOG4108REF Sporulation integral membrane protein ytvi BT10792_24875 ENOG4105BZN citrate synthase BT10792_24905 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BT10792_24920 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BT10792_24930 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BT10792_24945 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BT10792_24980 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BT10792_25005 ENOG4108JGH Tetr family transcriptional regulator BT10792_25010 ENOG4105CW7 secretion protein, HlyD family BT10792_25015 ENOG4105C0R drug resistance transporter emrb qaca subfamily BT10792_25045 ENOG4108RWN rrna methyltransferase BT10792_25055 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BT10792_25080 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BT10792_25110 ENOG4105FE9 pseudouridine synthase BT10792_25145 ENOG4105E0A ABC, transporter BT10792_25160 ENOG4105DR4 Methyltransferase BT10792_25175 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BT10792_25225 ENOG4105S6R Iron-hydroxamate transporter permease subunit BT10792_25245 ENOG4105CEY Amp-dependent synthetase and ligase BT10792_25250 ENOG4107Z3H Transcriptional regulator, TetR family BT10792_25270 ENOG4105K63 Thioredoxin BT10792_25275 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BT10792_25285 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BT10792_25295 ENOG4105E33 succinate dehydrogenase BT10792_25310 ENOG4105E14 MotA TolQ exbB proton channel BT10792_25325 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BT10792_25330 ENOG4108IUX (ABC) transporter BT10792_25340 ENOG4108Z40 Transcriptional regulator BT10792_25345 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BT10792_25360 ENOG41067S9 phage shock protein C, PspC BT10792_25395 ENOG4108PCX Major Facilitator BT10792_25405 ENOG4108XJQ germination protein BT10792_25415 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BT10792_25420 ENOG4105M59 Phosphodiesterase, mj0936 family BT10792_25535 ENOG4108QCI YvbH-like oligomerisation region BT10792_25565 ENOG4108IUQ atp-dependent protease BT10792_25585 ENOG4105K56 Transcriptional regulator BT10792_25610 ENOG4105D52 delta-aminolevulinic acid dehydratase BT10792_25620 ENOG41068KH stage VI sporulation protein D BT10792_25635 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BT10792_25660 ENOG4105DFF Rod shape-determining protein mreb BT10792_25680 ENOG4107QMS site-determining protein BT10792_25705 ENOG4105X36 (ribosomal) protein BT10792_25720 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BT10792_25735 ENOG4105C19 ABC transporter BT10792_25755 ENOG4108RPX mosc domain containing protein BT10792_25770 ENOG4108IYU L-aspartate oxidase BT10792_25775 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BT10792_25810 ENOG4108HUF Transporter BT10792_25825 ENOG41061AI Protein of unknown function (DUF2905) BT10792_25840 ENOG4105VIE preprotein translocase, subunit YajC BT10792_25855 ENOG4105CKP Polysaccharide Biosynthesis Protein BT10792_25865 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BT10792_25875 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BT10792_25885 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BT10792_25890 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BT10792_25925 ENOG4108VCI transcription factor, rsfa family BT10792_25940 ENOG4105C3J Cysteine desulfurase BT10792_25945 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BT10792_25955 ENOG4105C7H Helicase, RecD TraA family BT10792_25960 ENOG41060CR BT10792_26005 ENOG4105HHA aminodeoxychorismate lyase BT10792_26010 ENOG4108VQJ O-methyltransferase BT10792_26015 ENOG4105XYU peptidase (U32 family) BT10792_26020 ENOG4105CFP Peptidase U32 BT10792_26030 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BT10792_26065 ENOG4105C28 cystathionine BT10792_26075 ENOG4108EKI Dehydrogenase BT10792_26095 ENOG4105S6R Iron-hydroxamate transporter permease subunit BT10792_26140 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BT10792_26150 ENOG4105MIR Phenylalanine 4-monooxygenase BT10792_26155 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BT10792_26190 ENOG4108MUZ hydrolase BT10792_26195 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BT10792_26215 ENOG4108TVJ Nitroreductase BT10792_26240 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BT10792_26255 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BT10792_26260 ENOG4105CQW ribosome biogenesis GTPase YqeH BT10792_26270 ENOG410812S Rna-binding protein BT10792_26300 ENOG4105KQC Competence protein BT10792_26305 ENOG4108UK2 deaminase BT10792_26345 ENOG4105KVH Transcriptional regulator BT10792_26350 ENOG4105CSA Coproporphyrinogen iii oxidase BT10792_26380 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BT10792_26385 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BT10792_26400 ENOG4105KTH gatB Yqey BT10792_26410 ENOG41068P3 sporulation protein YqfC BT10792_26420 ENOG4105C9A Phoh family BT10792_26425 ENOG4105CTJ Metal Dependent Phosphohydrolase BT10792_26430 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BT10792_26435 ENOG4107YR5 Diacylglycerol kinase BT10792_26440 ENOG4105KG3 cytidine deaminase BT10792_26445 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BT10792_26480 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BT10792_26485 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BT10792_26500 ENOG4105EGD dinuclear metal center protein, YbgI family BT10792_26545 ENOG4105N80 Ferric uptake regulator, Fur family BT10792_26575 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BT10792_26600 ENOG4105C8U phosphate abc transporter BT10792_26605 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BT10792_26610 ENOG4108UTW Plays a role in the regulation of phosphate uptake BT10792_26625 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BT10792_26645 ENOG4105C5X domain protein BT10792_26670 ENOG4105C28 cystathionine BT10792_26685 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BT10792_26845 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BT10792_26860 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BT10792_26900 ENOG41080TC multidrug resistance protein BT10792_26925 ENOG4105WZW rhodanese family BT10792_26960 ENOG4107YBY Hydrolase BT10792_26980 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BT10792_26985 ENOG4105DC7 peptidase M24 BT10792_27015 ENOG4105KR5 Stage iii sporulation protein BT10792_27020 ENOG4108CQH stage III sporulation protein AC BT10792_27025 ENOG4105KQ4 Stage iii sporulation protein ad BT10792_27035 ENOG410644B Stage III sporulation protein af BT10792_27065 ENOG4108ZSR alkaline shock protein BT10792_27075 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BT10792_27105 ENOG4105DX0 Hemolysin A BT10792_27110 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BT10792_27115 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BT10792_27130 ENOG4107QQR Sporulation BT10792_27170 ENOG4107RDP Dehydrogenase BT10792_27175 ENOG4105CKM Branched-chain carboxylic acid kinase BT10792_27190 ENOG4105CPP Dehydrogenase, E1 component BT10792_27195 ENOG4105C7S Dehydrogenase BT10792_27235 ENOG4105E5Q amino acid AbC transporter BT10792_27240 ENOG4105CDA abc transporter atp-binding protein BT10792_27245 ENOG4108QEG Membrane BT10792_27270 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BT10792_27320 ENOG4105EJQ L-serine dehydratase BT10792_27325 ENOG4105II7 pyrroline-5-carboxylate reductase BT10792_27330 ENOG41069FQ Metallo-beta-lactamase superfamily BT10792_27335 ENOG4108IXY short-chain dehydrogenase reductase BT10792_27420 ENOG4105CGH 5'-nucleotidase BT10792_27455 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BT10792_27485 ENOG4108R6K riboflavin synthase, subunit alpha BT10792_27490 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BT10792_27510 ENOG4108YM7 Gcn5-related n-acetyltransferase BT10792_27515 ENOG4105ETE Transcriptional regulator (LacI family BT10792_27525 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BT10792_27545 ENOG4105RHY Pfam:UPF0157 BT10792_27580 ENOG4105I3K Ferric uptake regulator, Fur family BT10792_27615 ENOG4105D7N magnesium and cobalt transport protein CorA BT10792_27650 ENOG4105DVE abc transporter atp-binding protein BT10792_27655 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BT10792_27665 ENOG4105DZ1 carboxypeptidase BT10792_27670 ENOG41082AN stage II sporulation protein BT10792_27680 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BT10792_27685 ENOG4105C8J )-transporter BT10792_27705 ENOG41090VF Stage v sporulation protein ac BT10792_27730 ENOG4105J7I hydrolase BT10792_27740 ENOG4107ZE5 PPIases accelerate the folding of proteins BT10792_27785 ENOG4105CE4 GlcNAc 6-P deacetylase BT10792_27795 ENOG4105FDP GntR family transcriptional regulator BT10792_27805 ENOG4105CID antiterminator BT10792_27820 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BT10792_27840 ENOG4105BZU Histidine kinase BT10792_27850 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BT10792_27865 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BT10792_27910 ENOG4105DTD Dehydrogenase BT10792_27915 ENOG4105K7K Transcriptional regulator BT10792_27950 ENOG4105CHU acetyl-coa acetyltransferase BT10792_28005 ENOG4107FKK extracellular solute-binding protein family 1 BT10792_28015 ENOG4105EG2 ABC transporter, permease BT10792_28025 ENOG4105CHM Aminotransferase BT10792_28120 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BT10792_28125 ENOG4105EPM Diguanylate phosphodiesterase BT10792_28145 ENOG4107IN1 Protein of unknown function (DUF1797) BT10792_28155 ENOG4108XRC Protein of unknown function (DUF458) BT10792_28190 ENOG4107ZYR domain protein BT10792_28215 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BT10792_28230 ENOG4105CPP Dehydrogenase, E1 component BT10792_28280 ENOG4105CXN decarboxylase BT10792_28300 ENOG4105ECY inositol monophosphatase BT10792_28310 ENOG4105CI3 gtp-binding protein typa BT10792_28315 ENOG4105QA2 BT10792_28360 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BT10792_28405 ENOG4105EKQ RNA-directed DNA polymerase BT10792_28425 ENOG4106UY4 Inherit from COG: Scp-like extracellular BT10792_28460 ENOG4106H78 methyltransferase BT10792_28470 ENOG4105H20 Sporulation integral membrane protein YlbJ BT10792_28475 ENOG4105D78 K07001 NTE family protein BT10792_28480 ENOG41063PX domain protein BT10792_28490 ENOG4105KNH Nucleic acid-binding protein BT10792_28540 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BT10792_28560 ENOG4105CNI cell division protein FtsW BT10792_28565 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BT10792_28570 ENOG4105D4A Cell wall formation (By similarity) BT10792_28580 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BT10792_28585 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BT10792_28605 ENOG4105WR5 sporulation protein, YlmC YmxH family BT10792_28615 ENOG4105DFA alanine racemase domain protein BT10792_28625 ENOG41067XK integral membrane protein BT10792_28630 ENOG4105DBK s4 domain protein BT10792_28655 ENOG4105C34 Pseudouridine synthase BT10792_28690 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BT10792_28755 ENOG4105F23 Fibronectin-binding protein BT10792_28765 ENOG4105DSJ YicC domain protein BT10792_28785 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BT10792_28790 ENOG4105C25 Primosomal protein n' BT10792_28815 ENOG4108ZF3 Phosphatase BT10792_28825 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BT10792_28830 ENOG4105DJV ribulose-phosphate 3-epimerase BT10792_28860 ENOG4105CB5 ATP-dependent DNA helicase recG BT10792_28875 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BT10792_28880 ENOG4105CHR reductase BT10792_28900 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BT10792_28920 ENOG4105VB6 UPF0109 protein BT10792_28945 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BT10792_28960 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BT10792_28965 ENOG4105C79 DNA protecting protein DprA BT10792_28980 ENOG4108HE4 integrase family BT10792_29010 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BT10792_29020 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BT10792_29035 ENOG4105DZP Membrane-associated zinc metalloprotease BT10792_29045 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BT10792_29055 ENOG4105CHV Transcription elongation factor NusA BT10792_29060 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BT10792_29065 ENOG4105VHM ribosomal protein BT10792_29080 ENOG4105W7A Protein of unknown function (DUF503) BT10792_29125 ENOG4105E35 Dipicolinate synthase subunit A BT10792_29130 ENOG4108S0H Dipicolinic acid synthetase, b subunit BT10792_29190 ENOG4105CDU Replicative dna helicase BT10792_29350 ENOG41085W3 Transposase BT10792_29395 ENOG4108S0H Dipicolinic acid synthetase, b subunit BT10792_29400 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BT10792_29410 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BT10792_29440 ENOG4105FDP GntR family transcriptional regulator BT10792_29455 ENOG4105UIB (ABC) transporter BT10792_29480 ENOG4105XZV Protein of unknown function (DUF3243) BT10792_29495 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BT10792_29520 ENOG4105D48 metallophosphoesterase BT10792_29525 ENOG4105MCT stage V sporulation protein S BT10792_29530 ENOG4108IGT Dipeptidase BT10792_29535 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BT10792_29540 ENOG4105DQU oxidoreductase, subunit beta BT10792_29580 ENOG4105E0M Sulfatase BT10792_29595 ENOG4105F0V Cell wall hydrolase BT10792_29710 ENOG4105D03 DNA-3-methyladenine glycosylase II BT10792_29715 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BT10792_29765 ENOG4105E0A ABC, transporter BT10792_29770 ENOG4105NIV Esterase BT10792_29790 ENOG4105VPX protein, conserved in bacteria BT10792_29795 ENOG410681U heavy metal transport detoxification protein BT10792_29810 ENOG4105K70 DNA-binding protein BT10792_29840 ENOG4105C85 amino acid BT10792_29855 ENOG4108SJC Membrane BT10792_29860 ENOG4107QW4 alcohol dehydrogenase BT10792_29865 ENOG4105E98 transcriptional regulator DeoR family BT10792_29875 ENOG4105DM4 PTS System BT10792_29920 ENOG4106F1P AAA ATPase, central domain protein BT10792_29925 ENOG4106F1P AAA ATPase, central domain protein BT10792_29930 ENOG4106F1P AAA ATPase, central domain protein BT10792_29940 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BT10792_29945 ENOG4105CXI aluminum resistance protein BT10792_29950 ENOG4105KV4 Transcriptional regulator BT10792_29965 ENOG4105K7K Transcriptional regulator BT10792_30100 ENOG4105CHR reductase BT10792_30120 ENOG4105D7V transposase BT10792_30135 ENOG4105FQP Beta-lactamase BT10792_30250 ENOG4108JGH Tetr family transcriptional regulator BT10792_30330 ENOG4108VJ1 Transcriptional regulator (CarD family BT10792_30360 ENOG4105DRR Transcriptional regulator, GntR family BT10792_30490 ENOG4105BZU Histidine kinase BT10792_30495 ENOG4105EFI regulatoR BT10792_30515 ENOG4108IND Tetr family transcriptional regulator BT10792_30550 ENOG4105CEY Amp-dependent synthetase and ligase BT10792_30575 ENOG4107Y80 Major Facilitator superfamily BT10792_30595 ENOG4105CJZ response regulator BT10792_30700 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) BT10792_30715 ENOG4105C5E polysaccharide biosynthesis protein BT10792_30800 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BT10792_30875 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BT10792_30890 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BT10792_30895 ENOG4107QPK )-transporter BT10792_31040 ENOG4105D4Y metalloprotease BT10792_31060 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BT10792_31065 ENOG4108FPN Integrase BT10792_31215 ENOG4105D7V transposase BT10792_31245 ENOG4105TRI Hydrolase BT10792_31325 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) BT10792_31330 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BT10792_31345 ENOG4105C1G acyl-Coa dehydrogenase BT10792_31390 ENOG41069ER domain protein BT10792_31415 ENOG4105D7V transposase BT10792_31430 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BT10792_31445 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BT10792_31450 ENOG4105DR5 peptidase BT10792_31490 ENOG4105IIU Aminopeptidase BT10792_31515 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BT10792_31545 ENOG4105M6F mutator MutT protein BT10792_31550 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BT10792_31580 ENOG4105YWU small acid-soluble spore protein BT10792_31725 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BT10792_31805 ENOG4105EKQ RNA-directed DNA polymerase BT10792_31965 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BT10792_32055 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BT10792_32135 ENOG4105EKQ RNA-directed DNA polymerase BT10792_32185 ENOG4105DHF Membrane BT10792_32230 ENOG4108NGU Transcriptional regulator BT10792_32245 ENOG4105CUB amino acid BT10792_32255 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BT10792_32265 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BT10792_32280 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BT10792_32315 ENOG4105CAQ asparagine synthetase BT10792_32355 ENOG4105FQP Beta-lactamase BT10792_32395 ENOG4105E1J oxidoreductase BT10792_32410 ENOG4107S1E Beta-lactamase BT10792_32450 ENOG4105K70 DNA-binding protein BT10792_32455 ENOG4105KRN Transcriptional regulator, abrb family BT10792_32480 ENOG41085W3 Transposase BT10792_32495 ENOG4105D7V transposase BT10792_32510 ENOG4105DRR Transcriptional regulator, GntR family BT10792_32530 ENOG4105CUJ penicillin amidase BT10792_32575 ENOG4105CIF Ornithine Cyclodeaminase BT10792_32590 ENOG4105K70 DNA-binding protein BT10792_32605 ENOG4105KRN Transcriptional regulator, abrb family BT10792_32610 ENOG4108KS4 Spore coat protein BT10792_32635 ENOG4107SBE Glycosyl transferase (Group 1 BT10792_32655 ENOG4105DUX Transporter BT10792_32820 ENOG4105K4H Nlp p60 protein BT10792_32930 ENOG4105E2X shikimate dehydrogenase BT10792_32940 ENOG41088YA Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity) BT10792_32990 ENOG4105K70 DNA-binding protein BT10792_33290 ENOG4105DR5 peptidase BT10792_33360 ENOG4105EKQ RNA-directed DNA polymerase BT10792_33485 ENOG4105EKQ RNA-directed DNA polymerase BT10792_33685 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BT10792_33705 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BT10792_33870 ENOG4105EKQ RNA-directed DNA polymerase BT10792_34095 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BT10792_34285 ENOG4105K4H Nlp p60 protein