locus-tag	class	description
K8Z39_00015	COG3331	DNA recombination
K8Z39_00160	COG0582	viral genome integration into host DNA
K8Z39_00180	COG1266	CAAX protease self-immunity
K8Z39_00195	COG0488	(ABC) transporter
K8Z39_00205	COG0456	acetyltransferase
K8Z39_00210	COG1214	PFAM Peptidase M22, glycoprotease
K8Z39_00215	COG0802	atpase or kinase
K8Z39_00315	COG2183	response to ionizing radiation
K8Z39_00320	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z39_00325	COG0864	Transcriptional regulator
K8Z39_00330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z39_00335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z39_00345	COG0705	Rhomboid family
K8Z39_00350	COG4294	response to UV
K8Z39_00360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z39_00370	COG2814	Major facilitator Superfamily
K8Z39_00375	COG0531	amino acid
K8Z39_00385	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z39_00390	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z39_00410	COG0561	phosphatase activity
K8Z39_00420	COG4608	Belongs to the ABC transporter superfamily
K8Z39_00425	COG0444	Belongs to the ABC transporter superfamily
K8Z39_00430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z39_00435	COG0601	transmembrane transport
K8Z39_00440	COG0747	negative chemotaxis
K8Z39_00450	COG0488	(ABC) transporter
K8Z39_00470	COG5298	Protein conserved in bacteria
K8Z39_00490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_00500	COG1609	Transcriptional regulator
K8Z39_00510	COG0204	Acyl-transferase
K8Z39_00525	COG0697	spore germination
K8Z39_00540	COG1910	domain protein
K8Z39_00545	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z39_00550	COG4149	molybdate abc transporter
K8Z39_00565	COG0656	L-ascorbic acid biosynthetic process
K8Z39_00570	COG4166	transmembrane transport
K8Z39_00575	COG4166	transmembrane transport
K8Z39_00590	COG2207	Transcriptional regulator
K8Z39_00610	COG2814	Major facilitator Superfamily
K8Z39_00620	COG2271	Major facilitator Superfamily
K8Z39_00625	COG0277	FAD linked oxidase domain protein
K8Z39_00635	COG0604	alcohol dehydrogenase
K8Z39_00640	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_00645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z39_00650	COG2011	ABC-type metal ion transport system permease component
K8Z39_00655	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_00690	COG4856	YbbR-like protein
K8Z39_00695	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z39_00775	COG0726	polysaccharide deacetylase
K8Z39_00780	COG2194	sulfuric ester hydrolase activity
K8Z39_00790	COG0489	protein tyrosine kinase activity
K8Z39_00795	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z39_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z39_00865	COG0024	Methionine aminopeptidase
K8Z39_00875	COG0201	protein transport
K8Z39_00935	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z39_01000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z39_01005	COG1358	cellular component organization or biogenesis
K8Z39_01020	COG2813	Specifically methylates the guanine in position
K8Z39_01040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z39_01045	COG0250	Participates in transcription elongation, termination and antitermination
K8Z39_01050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z39_01065	COG3688	RNA-binding protein containing a PIN domain
K8Z39_01070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z39_01085	COG1045	serine acetyltransferase
K8Z39_01105	COG4956	integral membrane protein (PIN domain superfamily)
K8Z39_01115	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z39_01120	COG0542	response to heat
K8Z39_01130	COG3880	PFAM UvrB UvrC protein
K8Z39_01220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z39_01225	COG1396	sequence-specific DNA binding
K8Z39_01230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z39_01235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z39_01240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z39_01245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_01250	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z39_01255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z39_01260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z39_01275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z39_01280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z39_01290	COG2208	phosphoserine phosphatase activity
K8Z39_01305	COG1098	S1 RNA binding domain
K8Z39_01325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z39_01330	COG3956	TIGRFAM MazG family protein
K8Z39_01335	COG2244	polysaccharide biosynthetic process
K8Z39_01340	COG2002	toxin-antitoxin pair type II binding
K8Z39_01345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z39_01375	COG0251	oxidation-reduction process
K8Z39_01380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z39_01395	COG4466	Protein conserved in bacteria
K8Z39_01415	COG0084	hydrolase, TatD family'
K8Z39_01425	COG2002	toxin-antitoxin pair type II binding
K8Z39_01430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z39_01440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z39_01450	COG1774	PSP1 C-terminal conserved region
K8Z39_01455	COG0470	DNA polymerase III
K8Z39_01465	COG1982	Orn Lys Arg decarboxylase major
K8Z39_01520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z39_01530	COG0590	tRNA wobble adenosine to inosine editing
K8Z39_01535	COG1335	isochorismatase
K8Z39_01540	COG1428	Deoxynucleoside kinase
K8Z39_01545	COG1428	Deoxynucleoside kinase
K8Z39_01575	COG1686	Belongs to the peptidase S11 family
K8Z39_01580	COG0517	IMP dehydrogenase activity
K8Z39_01580	COG0516	GMP reductase activity
K8Z39_01615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z39_01620	COG0187	DNA topoisomerase II activity
K8Z39_01630	COG2501	S4 domain
K8Z39_01635	COG0592	DNA-directed DNA polymerase activity
K8Z39_01645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z39_01660	COG1847	R3H domain protein
K8Z39_01685	COG1192	Involved in chromosome partitioning
K8Z39_01690	COG1475	DNA binding
K8Z39_01700	COG0668	transmembrane transport
K8Z39_01705	COG4481	Protein conserved in bacteria
K8Z39_01710	COG0012	GTP binding
K8Z39_01730	COG4241	membrane
K8Z39_01735	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z39_01745	COG0305	Participates in initiation and elongation during chromosome replication
K8Z39_01775	COG0745	RESPONSE REGULATOR receiver
K8Z39_01780	COG5002	protein histidine kinase activity
K8Z39_01790	COG4853	Protein conserved in bacteria
K8Z39_01795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z39_01800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z39_01815	COG5002	protein histidine kinase activity
K8Z39_01850	COG1272	protein, Hemolysin III
K8Z39_01855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z39_01890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z39_01895	COG2814	Major facilitator Superfamily
K8Z39_01900	COG3275	phosphorelay sensor kinase activity
K8Z39_01920	COG0628	permease
K8Z39_01930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z39_01935	COG1309	transcriptional regulator
K8Z39_01940	COG0488	(ABC) transporter
K8Z39_01945	COG0463	Glycosyl transferase, family 2
K8Z39_01950	COG4485	Bacterial membrane protein, YfhO
K8Z39_01960	COG1216	Glycosyl transferase, family 2
K8Z39_01975	COG1216	Glycosyl transferase, family 2
K8Z39_01980	COG1607	acyl-coa hydrolase
K8Z39_01990	COG0840	transmembrane signaling receptor activity
K8Z39_02005	COG0438	transferase activity, transferring glycosyl groups
K8Z39_02015	COG0477	Major facilitator Superfamily
K8Z39_02020	COG3279	Response regulator of the LytR AlgR family
K8Z39_02025	COG1966	Carbon starvation protein
K8Z39_02030	COG2879	small protein
K8Z39_02035	COG3706	GGDEF domain
K8Z39_02040	COG0351	phosphomethylpyrimidine kinase
K8Z39_02045	COG4585	Histidine kinase
K8Z39_02045	COG2203	Gaf domain
K8Z39_02050	COG2197	response regulator
K8Z39_02060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_02065	COG1011	Hydrolase
K8Z39_02075	COG2873	o-acetylhomoserine
K8Z39_02085	COG0460	homoserine dehydrogenase
K8Z39_02095	COG1609	Transcriptional regulator
K8Z39_02100	COG2755	lipolytic protein G-D-S-L family
K8Z39_02105	COG1131	(ABC) transporter
K8Z39_02120	COG2814	Major facilitator Superfamily
K8Z39_02125	COG0561	phosphatase activity
K8Z39_02130	COG2233	PERMEase
K8Z39_02135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z39_02145	COG2363	Small membrane protein
K8Z39_02155	COG3773	Cell wall hydrolase
K8Z39_02170	COG0280	phosphate acetyltransferase
K8Z39_02190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_02195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_02200	COG1120	ATPase activity
K8Z39_02205	COG2801	Transposase and inactivated derivatives
K8Z39_02215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_02220	COG1078	dGTPase activity
K8Z39_02230	COG1994	Peptidase M50
K8Z39_02240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_02245	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_02250	COG0789	Transcriptional regulator
K8Z39_02255	COG2814	Major facilitator Superfamily
K8Z39_02285	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z39_02290	COG4506	Protein conserved in bacteria
K8Z39_02300	COG1595	DNA-templated transcription, initiation
K8Z39_02320	COG2234	aminopeptidase activity
K8Z39_02340	COG0024	Methionine aminopeptidase
K8Z39_02345	COG1131	(ABC) transporter
K8Z39_02350	COG0842	Transport permease protein
K8Z39_02355	COG4585	Histidine kinase
K8Z39_02360	COG2197	response regulator
K8Z39_02365	COG3227	Zinc metalloprotease (Elastase)
K8Z39_02380	COG5001	Diguanylate cyclase
K8Z39_02380	COG3300	MHYT domain
K8Z39_02390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_02395	COG2181	nitrate reductase activity
K8Z39_02395	COG0247	lactate metabolic process
K8Z39_02400	COG0183	Belongs to the thiolase family
K8Z39_02405	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z39_02410	COG1960	acyl-CoA dehydrogenase activity
K8Z39_02415	COG1960	acyl-CoA dehydrogenase activity
K8Z39_02425	COG3343	RNA polymerase activity
K8Z39_02435	COG4821	SIS domain
K8Z39_02455	COG1494	fructose-1,6-bisphosphatase
K8Z39_02460	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z39_02495	COG0009	L-threonylcarbamoyladenylate synthase
K8Z39_02510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z39_02515	COG2259	Doxx family
K8Z39_02530	COG0698	ribose 5-phosphate isomerase
K8Z39_02565	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z39_02615	COG5001	Diguanylate cyclase
K8Z39_02615	COG3300	MHYT domain
K8Z39_02630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z39_02650	COG0839	Belongs to the complex I subunit 6 family
K8Z39_02660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z39_02665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z39_02670	COG1007	ATP synthesis coupled electron transport
K8Z39_02675	COG4836	Membrane
K8Z39_02690	COG2385	sporulation resulting in formation of a cellular spore
K8Z39_02695	COG3279	Response regulator of the LytR AlgR family
K8Z39_02710	COG0739	heme binding
K8Z39_02720	COG1609	Transcriptional regulator
K8Z39_02735	COG0489	protein tyrosine kinase activity
K8Z39_02740	COG3944	biosynthesis protein
K8Z39_02745	COG0489	protein tyrosine kinase activity
K8Z39_02750	COG4464	protein tyrosine phosphatase activity
K8Z39_02755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z39_02770	COG1216	Glycosyl transferase, family 2
K8Z39_02780	COG0438	transferase activity, transferring glycosyl groups
K8Z39_02785	COG0463	Glycosyl transferase, family 2
K8Z39_02790	COG1215	transferase activity, transferring glycosyl groups
K8Z39_02795	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z39_02800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z39_02805	COG1316	TRANSCRIPTIONal
K8Z39_02815	COG0745	RESPONSE REGULATOR receiver
K8Z39_02820	COG5002	protein histidine kinase activity
K8Z39_02845	COG1136	(ABC) transporter
K8Z39_02850	COG0577	efflux transmembrane transporter activity
K8Z39_02890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z39_02895	COG4715	Zinc finger, swim domain protein
K8Z39_02920	COG3584	3D domain protein
K8Z39_02920	COG1388	LysM domain
K8Z39_02925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z39_02940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_02945	COG0791	NLP P60 protein
K8Z39_02945	COG1388	LysM domain
K8Z39_02960	COG1368	sulfuric ester hydrolase activity
K8Z39_02970	COG2389	metal-binding protein
K8Z39_02985	COG1620	l-lactate permease
K8Z39_02995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z39_03000	COG1294	oxidase, subunit
K8Z39_03005	COG1271	oxidase subunit
K8Z39_03015	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K8Z39_03020	COG0583	DNA-binding transcription factor activity
K8Z39_03025	COG1511	domain protein
K8Z39_03040	COG1301	dicarboxylic acid transport
K8Z39_03045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z39_03055	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z39_03065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z39_03070	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z39_03075	COG1486	melibiose metabolic process
K8Z39_03095	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z39_03095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z39_03105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z39_03110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z39_03115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z39_03120	COG1316	TRANSCRIPTIONal
K8Z39_03125	COG1739	Uncharacterized protein family UPF0029
K8Z39_03130	COG1307	EDD domain protein, DegV family
K8Z39_03135	COG1733	regulation of RNA biosynthetic process
K8Z39_03140	COG0791	NLP P60 protein
K8Z39_03140	COG1388	LysM domain
K8Z39_03145	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z39_03150	COG1040	competence protein
K8Z39_03155	COG1278	Cold shock
K8Z39_03160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z39_03190	COG1131	(ABC) transporter
K8Z39_03215	COG2884	Cell division ATP-binding protein ftsE
K8Z39_03220	COG2177	Part of the ABC transporter FtsEX involved in
K8Z39_03225	COG0793	Belongs to the peptidase S41A family
K8Z39_03225	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_03230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z39_03255	COG0488	(ABC) transporter
K8Z39_03260	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z39_03270	COG0583	DNA-binding transcription factor activity
K8Z39_03290	COG0789	Transcriptional regulator
K8Z39_03305	COG0556	nucleotide-excision repair
K8Z39_03310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z39_03320	COG1950	PFAM Membrane protein of
K8Z39_03340	COG0110	maltose O-acetyltransferase activity
K8Z39_03345	COG0457	Tetratricopeptide repeat
K8Z39_03350	COG0492	ferredoxin-NADP+ reductase activity
K8Z39_03360	COG1051	belongs to the nudix hydrolase family
K8Z39_03370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z39_03380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z39_03390	COG2323	membrane
K8Z39_03405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z39_03430	COG0582	viral genome integration into host DNA
K8Z39_03460	COG3646	Phage regulatory protein
K8Z39_03550	COG3331	DNA recombination
K8Z39_03685	COG4824	toxin secretion phage lysis holin
K8Z39_03690	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_03690	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_03690	COG1388	LysM domain
K8Z39_03715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z39_03730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z39_03765	COG1346	cytolysis
K8Z39_03770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z39_03775	COG1647	Serine aminopeptidase, S33
K8Z39_03780	COG0557	exoribonuclease II activity
K8Z39_03825	COG0745	RESPONSE REGULATOR receiver
K8Z39_03870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_03875	COG0488	(ABC) transporter
K8Z39_03930	COG1252	NADH dehydrogenase
K8Z39_03940	COG1733	regulation of RNA biosynthetic process
K8Z39_03945	COG2814	Major facilitator Superfamily
K8Z39_03950	COG0656	L-ascorbic acid biosynthetic process
K8Z39_03965	COG2910	NAD(P)H-binding
K8Z39_03970	COG1115	amino acid carrier protein
K8Z39_03975	COG1115	amino acid carrier protein
K8Z39_03980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_03985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_03990	COG2311	Membrane
K8Z39_03995	COG1528	Iron-storage protein
K8Z39_04005	COG1611	Belongs to the LOG family
K8Z39_04020	COG0783	Belongs to the Dps family
K8Z39_04025	COG1115	amino acid carrier protein
K8Z39_04030	COG0490	domain, Protein
K8Z39_04035	COG0475	glutathione-regulated potassium exporter activity
K8Z39_04040	COG0586	Pfam SNARE associated Golgi protein
K8Z39_04060	COG3227	Zinc metalloprotease (Elastase)
K8Z39_04085	COG4974	Belongs to the 'phage' integrase family
K8Z39_04105	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z39_04110	COG0840	transmembrane signaling receptor activity
K8Z39_04140	COG5002	protein histidine kinase activity
K8Z39_04145	COG0745	RESPONSE REGULATOR receiver
K8Z39_04150	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z39_04160	COG0586	Pfam SNARE associated Golgi protein
K8Z39_04195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_04215	COG0531	amino acid
K8Z39_04220	COG2814	Major facilitator Superfamily
K8Z39_04235	COG0840	transmembrane signaling receptor activity
K8Z39_04240	COG0011	TIGRFAM Protein of
K8Z39_04255	COG1686	Belongs to the peptidase S11 family
K8Z39_04265	COG1024	Enoyl-CoA hydratase
K8Z39_04265	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z39_04270	COG0183	Belongs to the thiolase family
K8Z39_04275	COG1960	acyl-CoA dehydrogenase activity
K8Z39_04280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_04285	COG1309	transcriptional regulator
K8Z39_04300	COG0039	L-malate dehydrogenase activity
K8Z39_04320	COG1393	Belongs to the ArsC family
K8Z39_04330	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z39_04335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_04350	COG2011	ABC-type metal ion transport system permease component
K8Z39_04355	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_04360	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_04365	COG0396	ATPase activity
K8Z39_04370	COG0719	Fe-S assembly protein
K8Z39_04375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z39_04380	COG0822	iron-sulfur transferase activity
K8Z39_04385	COG0719	Fe-S assembly protein
K8Z39_04390	COG0582	viral genome integration into host DNA
K8Z39_04395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z39_04475	COG1396	sequence-specific DNA binding
K8Z39_04615	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_04640	COG2801	Transposase and inactivated derivatives
K8Z39_04645	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_04650	COG3377	Domain of unknown function (DUF1805)
K8Z39_04660	COG0739	heme binding
K8Z39_04685	COG4377	Putative membrane peptidase family (DUF2324)
K8Z39_04690	COG0789	Transcriptional regulator
K8Z39_04700	COG4470	Protein conserved in bacteria
K8Z39_04720	COG1494	fructose-1,6-bisphosphatase
K8Z39_04725	COG2445	Protein of unknown function DUF86
K8Z39_04735	COG0647	UMP catabolic process
K8Z39_04740	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z39_04750	COG1358	cellular component organization or biogenesis
K8Z39_04770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z39_04775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z39_04785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z39_04790	COG4837	Protein of unknown function (DUF1462)
K8Z39_04835	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z39_04840	COG0390	transport system, permease component
K8Z39_04855	COG1252	NADH dehydrogenase
K8Z39_04870	COG0316	Belongs to the HesB IscA family
K8Z39_04905	COG3620	sequence-specific DNA binding
K8Z39_04920	COG3645	SOS response
K8Z39_04920	COG3646	Phage regulatory protein
K8Z39_04945	COG1191	sigma factor activity
K8Z39_05080	COG4824	toxin secretion phage lysis holin
K8Z39_05085	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_05085	COG1388	LysM domain
K8Z39_05085	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_05140	COG1683	Conserved Protein
K8Z39_05170	COG1252	NADH dehydrogenase
K8Z39_05185	COG3584	3D domain protein
K8Z39_05200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z39_05205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z39_05210	COG1268	BioY protein
K8Z39_05220	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z39_05245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z39_05250	COG5018	Exonuclease
K8Z39_05270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z39_05280	COG2267	carboxylic ester hydrolase activity
K8Z39_05285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z39_05295	COG0436	Aminotransferase
K8Z39_05300	COG1098	S1 RNA binding domain
K8Z39_05305	COG2155	Conserved Protein
K8Z39_05320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z39_05325	COG1285	pathogenesis
K8Z39_05360	COG0544	peptidyl-prolyl cis-trans isomerase activity
K8Z39_05480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z39_05490	COG0058	SHG alpha-glucan phosphorylase activity
K8Z39_05515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z39_05520	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z39_05525	COG1169	isochorismate synthase
K8Z39_05535	COG0596	Alpha beta hydrolase
K8Z39_05540	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z39_05565	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z39_05585	COG3964	amidohydrolase
K8Z39_05605	COG2188	Transcriptional regulator
K8Z39_05635	COG0577	efflux transmembrane transporter activity
K8Z39_05640	COG1136	(ABC) transporter
K8Z39_05645	COG0577	efflux transmembrane transporter activity
K8Z39_05650	COG0577	efflux transmembrane transporter activity
K8Z39_05655	COG2205	protein histidine kinase activity
K8Z39_05660	COG0745	RESPONSE REGULATOR receiver
K8Z39_05665	COG0640	Transcriptional regulator
K8Z39_05670	COG5658	integral membrane protein
K8Z39_05680	COG3708	Transcriptional regulator
K8Z39_05680	COG2207	Transcriptional regulator
K8Z39_05685	COG1136	(ABC) transporter
K8Z39_05690	COG0577	efflux transmembrane transporter activity
K8Z39_05700	COG0586	Pfam SNARE associated Golgi protein
K8Z39_05725	COG1597	lipid kinase activity
K8Z39_05730	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z39_05755	COG0745	RESPONSE REGULATOR receiver
K8Z39_05760	COG5002	protein histidine kinase activity
K8Z39_05800	COG1842	Phage shock protein A
K8Z39_05820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_05835	COG2801	Transposase and inactivated derivatives
K8Z39_05845	COG1294	oxidase, subunit
K8Z39_05850	COG1271	oxidase subunit
K8Z39_05865	COG1854	S-ribosylhomocysteine lyase activity
K8Z39_05895	COG0494	nUDIX hydrolase
K8Z39_05920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_05925	COG1116	anion transmembrane transporter activity
K8Z39_05930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z39_05955	COG1368	sulfuric ester hydrolase activity
K8Z39_05960	COG2267	carboxylic ester hydrolase activity
K8Z39_05965	COG3852	Histidine kinase
K8Z39_05970	COG5002	protein histidine kinase activity
K8Z39_05985	COG1349	DNA-binding transcription factor activity
K8Z39_06030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_06050	COG0438	transferase activity, transferring glycosyl groups
K8Z39_06055	COG0671	phosphoesterase, PA-phosphatase related
K8Z39_06060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z39_06065	COG2267	carboxylic ester hydrolase activity
K8Z39_06085	COG1794	racemase activity, acting on amino acids and derivatives
K8Z39_06090	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z39_06095	COG1242	4 iron, 4 sulfur cluster binding
K8Z39_06115	COG1136	(ABC) transporter
K8Z39_06125	COG0582	viral genome integration into host DNA
K8Z39_06130	COG0490	domain, Protein
K8Z39_06135	COG0475	glutathione-regulated potassium exporter activity
K8Z39_06140	COG2814	Major facilitator Superfamily
K8Z39_06185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z39_06195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_06215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z39_06220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_06230	COG0303	'Molybdopterin
K8Z39_06235	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z39_06240	COG0314	molybdopterin synthase activity
K8Z39_06265	COG1329	Transcriptional regulator
K8Z39_06285	COG3832	glyoxalase III activity
K8Z39_06295	COG2814	Major facilitator Superfamily
K8Z39_06300	COG2081	HI0933 family
K8Z39_06305	COG2244	polysaccharide biosynthetic process
K8Z39_06310	COG1187	pseudouridine synthase activity
K8Z39_06315	COG1349	DNA-binding transcription factor activity
K8Z39_06320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z39_06330	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z39_06335	COG0510	thiamine kinase activity
K8Z39_06350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_06360	COG1363	Peptidase, m42
K8Z39_06365	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z39_06370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_06380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z39_06395	COG1674	ftsk spoiiie
K8Z39_06410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_06425	COG2309	aminopeptidase activity
K8Z39_06435	COG3118	belongs to the thioredoxin family
K8Z39_06440	COG4851	CamS sex pheromone cAM373 precursor
K8Z39_06445	COG1605	Chorismate mutase
K8Z39_06445	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z39_06450	COG1609	Transcriptional regulator
K8Z39_06485	COG3279	Response regulator of the LytR AlgR family
K8Z39_06505	COG2972	Histidine kinase
K8Z39_06505	COG0745	RESPONSE REGULATOR receiver
K8Z39_06510	COG0666	response to abiotic stimulus
K8Z39_06520	COG0745	RESPONSE REGULATOR receiver
K8Z39_06535	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z39_06540	COG0517	IMP dehydrogenase activity
K8Z39_06545	COG0454	-acetyltransferase
K8Z39_06550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z39_06555	COG0110	maltose O-acetyltransferase activity
K8Z39_06565	COG1595	DNA-templated transcription, initiation
K8Z39_06615	COG0626	cystathionine gamma-synthase activity
K8Z39_06620	COG1956	GAF domain-containing protein
K8Z39_06625	COG1309	transcriptional regulator
K8Z39_06630	COG0697	spore germination
K8Z39_06635	COG0583	DNA-binding transcription factor activity
K8Z39_06645	COG1104	cysteine desulfurase activity
K8Z39_06660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z39_06670	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z39_06685	COG3874	Sporulation protein YtfJ
K8Z39_06690	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z39_06695	COG0827	DNA restriction-modification system
K8Z39_06720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_06765	COG0589	response to stress
K8Z39_06770	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_06785	COG0662	Cupin 2, conserved barrel domain protein
K8Z39_06825	COG0006	proline dipeptidase activity
K8Z39_06840	COG4109	DRTGG domain
K8Z39_06855	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z39_06870	COG0587	DNA-directed DNA polymerase activity
K8Z39_06875	COG0281	malic enzyme
K8Z39_06880	COG1725	Transcriptional regulator
K8Z39_06905	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z39_06910	COG0628	permease
K8Z39_06920	COG0372	Belongs to the citrate synthase family
K8Z39_06925	COG0538	isocitrate dehydrogenase activity
K8Z39_06945	COG0745	RESPONSE REGULATOR receiver
K8Z39_06950	COG5002	protein histidine kinase activity
K8Z39_06955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z39_06955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z39_06965	COG1971	Probably functions as a manganese efflux pump
K8Z39_06975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z39_06980	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z39_06990	COG3611	Membrane attachment protein
K8Z39_06995	COG1484	DNA-dependent DNA replication
K8Z39_07010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z39_07035	COG1363	Peptidase, m42
K8Z39_07040	COG1309	transcriptional regulator
K8Z39_07045	COG1566	PFAM secretion protein HlyD family protein
K8Z39_07050	COG2814	Major facilitator Superfamily
K8Z39_07070	COG1418	mRNA catabolic process
K8Z39_07080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z39_07125	COG1286	toxin biosynthetic process
K8Z39_07130	COG1796	DNA polymerase
K8Z39_07130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z39_07140	COG1187	pseudouridine synthase activity
K8Z39_07145	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_07150	COG5386	Cell surface protein
K8Z39_07160	COG5386	Cell surface protein
K8Z39_07175	COG1120	ATPase activity
K8Z39_07180	COG4509	Sortase family
K8Z39_07190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z39_07195	COG4895	conserved protein (DUF2196)
K8Z39_07205	COG0745	RESPONSE REGULATOR receiver
K8Z39_07210	COG2205	protein histidine kinase activity
K8Z39_07215	COG1131	(ABC) transporter
K8Z39_07245	COG2318	DinB family
K8Z39_07270	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_07275	COG1309	transcriptional regulator
K8Z39_07280	COG1024	Enoyl-CoA hydratase
K8Z39_07285	COG2086	electron transfer activity
K8Z39_07290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z39_07295	COG3118	belongs to the thioredoxin family
K8Z39_07305	COG1719	4-vinyl reductase, 4VR
K8Z39_07310	COG2009	succinate dehydrogenase
K8Z39_07315	COG1053	succinate dehydrogenase
K8Z39_07320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z39_07325	COG0824	Thioesterase
K8Z39_07330	COG1876	peptidase activity
K8Z39_07335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z39_07340	COG1360	Flagellar Motor Protein
K8Z39_07345	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z39_07350	COG4152	abc transporter atp-binding protein
K8Z39_07355	COG1668	transmembrane transport
K8Z39_07360	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_07370	COG0697	spore germination
K8Z39_07375	COG1396	sequence-specific DNA binding
K8Z39_07380	COG1983	PspC domain protein
K8Z39_07385	COG0402	S-adenosylhomocysteine deaminase activity
K8Z39_07390	COG2233	PERMEase
K8Z39_07395	COG2197	response regulator
K8Z39_07410	COG5401	PFAM Sporulation and spore germination
K8Z39_07425	COG0622	Phosphoesterase
K8Z39_07565	COG0470	DNA polymerase III
K8Z39_07565	COG1067	ATP-dependent peptidase activity
K8Z39_07580	COG1764	response to oxidative stress
K8Z39_07585	COG1846	Transcriptional regulator
K8Z39_07595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z39_07605	COG1587	Uroporphyrinogen-III synthase
K8Z39_07610	COG0113	porphobilinogen synthase activity
K8Z39_07620	COG1388	LysM domain
K8Z39_07635	COG0285	dihydrofolate synthase activity
K8Z39_07655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z39_07675	COG3646	Phage regulatory protein
K8Z39_07755	COG3331	DNA recombination
K8Z39_07765	COG1595	DNA-templated transcription, initiation
K8Z39_07880	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_07910	COG2003	Belongs to the UPF0758 family
K8Z39_07940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K8Z39_07965	COG1077	Cell shape determining protein MreB Mrl
K8Z39_07985	COG2894	cell division
K8Z39_07990	COG0739	heme binding
K8Z39_07995	COG1994	Peptidase M50
K8Z39_08000	COG1530	ribonuclease E activity
K8Z39_08010	COG2868	ribosomal protein
K8Z39_08020	COG3290	protein histidine kinase activity
K8Z39_08030	COG0745	RESPONSE REGULATOR receiver
K8Z39_08035	COG5002	protein histidine kinase activity
K8Z39_08040	COG1136	(ABC) transporter
K8Z39_08045	COG0577	efflux transmembrane transporter activity
K8Z39_08050	COG0577	efflux transmembrane transporter activity
K8Z39_08055	COG0077	Prephenate dehydratase
K8Z39_08060	COG2258	MOSC domain
K8Z39_08065	COG1827	regulation of RNA biosynthetic process
K8Z39_08070	COG1104	cysteine desulfurase activity
K8Z39_08075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z39_08080	COG0157	Belongs to the NadC ModD family
K8Z39_08110	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z39_08140	COG1862	Preprotein translocase
K8Z39_08150	COG2323	membrane
K8Z39_08155	COG2244	polysaccharide biosynthetic process
K8Z39_08165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z39_08165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z39_08170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z39_08175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z39_08175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z39_08185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z39_08210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z39_08220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z39_08225	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_08230	COG1104	cysteine desulfurase activity
K8Z39_08245	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z39_08265	COG0628	permease
K8Z39_08295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z39_08300	COG4122	O-methyltransferase activity
K8Z39_08305	COG0826	peptidase U32
K8Z39_08310	COG0826	peptidase U32
K8Z39_08320	COG0582	viral genome integration into host DNA
K8Z39_08330	COG1396	sequence-specific DNA binding
K8Z39_08445	COG3331	DNA recombination
K8Z39_08505	COG5484	DNA packaging
K8Z39_08505	COG3728	DNA packaging
K8Z39_08600	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z39_08610	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_08610	COG1388	LysM domain
K8Z39_08610	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_08685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z39_08690	COG0626	cystathionine gamma-synthase activity
K8Z39_08695	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_08695	COG1454	alcohol dehydrogenase
K8Z39_08705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_08745	COG2259	Doxx family
K8Z39_08750	COG2514	catechol 2,3-dioxygenase activity
K8Z39_08760	COG3186	Phenylalanine-4-hydroxylase
K8Z39_08805	COG2267	carboxylic ester hydrolase activity
K8Z39_08815	COG1785	Belongs to the alkaline phosphatase family
K8Z39_08825	COG2357	RelA SpoT domain protein
K8Z39_08830	COG0778	Nitroreductase
K8Z39_08865	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z39_08870	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z39_08880	COG1534	Rna-binding protein
K8Z39_08890	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z39_08895	COG0799	negative regulation of ribosome biogenesis
K8Z39_08900	COG2226	methyltransferase
K8Z39_08905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z39_08910	COG1596	polysaccharide export
K8Z39_08910	COG1555	photosystem II stabilization
K8Z39_08915	COG2131	deaminase
K8Z39_08920	COG2333	competence protein COMEC
K8Z39_08920	COG0658	competence protein
K8Z39_08930	COG1466	dna polymerase III delta subunit
K8Z39_08955	COG1733	regulation of RNA biosynthetic process
K8Z39_08960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z39_08990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z39_08995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z39_09000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z39_09005	COG1610	YqeY-like protein
K8Z39_09020	COG1702	phosphate starvation-inducible protein PhoH
K8Z39_09025	COG1480	7TM receptor with intracellular HD hydrolase
K8Z39_09035	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z39_09040	COG0295	cytidine deaminase activity
K8Z39_09045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z39_09060	COG0517	IMP dehydrogenase activity
K8Z39_09075	COG0358	DNA primase activity
K8Z39_09080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z39_09090	COG2384	SAM-dependent methyltransferase
K8Z39_09095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z39_09125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_09130	COG1121	(ABC) transporter
K8Z39_09135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z39_09140	COG0735	belongs to the Fur family
K8Z39_09155	COG5521	maltodextrose utilization protein MalA
K8Z39_09165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z39_09170	COG0477	Major facilitator Superfamily
K8Z39_09175	COG0768	penicillin binding
K8Z39_09185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z39_09190	COG0573	inorganic phosphate transmembrane transporter activity
K8Z39_09195	COG0573	inorganic phosphate transmembrane transporter activity
K8Z39_09205	COG0704	Plays a role in the regulation of phosphate uptake
K8Z39_09210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z39_09215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z39_09220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z39_09225	COG4483	Protein conserved in bacteria
K8Z39_09230	COG1940	carbohydrate kinase activity
K8Z39_09240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_09260	COG0626	cystathionine gamma-synthase activity
K8Z39_09265	COG0626	cystathionine gamma-synthase activity
K8Z39_09270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z39_09270	COG0646	methionine synthase
K8Z39_09275	COG1410	methionine synthase
K8Z39_09275	COG0646	methionine synthase
K8Z39_09330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z39_09335	COG1459	type II secretion system
K8Z39_09380	COG1396	sequence-specific DNA binding
K8Z39_09390	COG3646	Phage regulatory protein
K8Z39_09415	COG1484	DNA-dependent DNA replication
K8Z39_09425	COG2002	toxin-antitoxin pair type II binding
K8Z39_09485	COG0582	viral genome integration into host DNA
K8Z39_09540	COG0740	serine-type endopeptidase activity
K8Z39_09615	COG4824	toxin secretion phage lysis holin
K8Z39_09700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z39_09730	COG1725	Transcriptional regulator
K8Z39_09735	COG1131	(ABC) transporter
K8Z39_09765	COG2076	Multidrug Resistance protein
K8Z39_09770	COG2076	Multidrug Resistance protein
K8Z39_09780	COG1609	Transcriptional regulator
K8Z39_09790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_09830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z39_09840	COG3872	metal-dependent enzyme
K8Z39_09855	COG0006	proline dipeptidase activity
K8Z39_09880	COG3854	ATPases associated with a variety of cellular activities
K8Z39_09925	COG0511	ligase activity, forming carbon-carbon bonds
K8Z39_09930	COG0439	Biotin carboxylase
K8Z39_09935	COG1302	Protein conserved in bacteria
K8Z39_09960	COG0142	geranyltranstransferase activity
K8Z39_09970	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z39_09980	COG0497	DNA recombination
K8Z39_09985	COG0750	zinc metalloprotease
K8Z39_10000	COG3093	addiction module antidote protein HigA
K8Z39_10005	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_10015	COG3290	protein histidine kinase activity
K8Z39_10015	COG3829	transcription factor binding
K8Z39_10020	COG0280	phosphate acetyltransferase
K8Z39_10035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z39_10040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z39_10045	COG0022	dehydrogenase e1 component
K8Z39_10050	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z39_10060	COG0772	Belongs to the SEDS family
K8Z39_10065	COG2323	membrane
K8Z39_10085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_10090	COG0765	amino acid transport
K8Z39_10095	COG1126	abc transporter atp-binding protein
K8Z39_10100	COG4129	membrane
K8Z39_10105	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z39_10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_10125	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z39_10135	COG1285	pathogenesis
K8Z39_10165	COG1760	l-serine dehydratase
K8Z39_10170	COG1760	l-serine dehydratase
K8Z39_10175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z39_10180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_10185	COG0300	oxidoreductase activity
K8Z39_10230	COG1522	sequence-specific DNA binding
K8Z39_10240	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_10245	COG1757	Na H antiporter
K8Z39_10255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z39_10270	COG2226	methyltransferase
K8Z39_10270	COG1073	alpha beta
K8Z39_10300	COG0307	riboflavin synthase, alpha
K8Z39_10305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_10305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_10320	COG1073	alpha beta
K8Z39_10325	COG0456	acetyltransferase
K8Z39_10330	COG1609	Transcriptional regulator
K8Z39_10335	COG2056	Na+-H+ antiporter family
K8Z39_10340	COG0596	Alpha beta hydrolase
K8Z39_10370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z39_10370	COG0456	acetyltransferase
K8Z39_10375	COG0656	L-ascorbic acid biosynthetic process
K8Z39_10380	COG0667	Aldo Keto reductase
K8Z39_10400	COG1300	Membrane
K8Z39_10405	COG0735	belongs to the Fur family
K8Z39_10415	COG4974	Belongs to the 'phage' integrase family
K8Z39_10440	COG0598	Magnesium transport protein CorA
K8Z39_10455	COG1846	Transcriptional regulator
K8Z39_10470	COG1131	(ABC) transporter
K8Z39_10475	COG1725	Transcriptional regulator
K8Z39_10480	COG1686	Belongs to the peptidase S11 family
K8Z39_10525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z39_10540	COG0697	spore germination
K8Z39_10545	COG0561	phosphatase activity
K8Z39_10550	COG4086	secreted protein
K8Z39_10555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z39_10560	COG0456	acetyltransferase
K8Z39_10565	COG1547	Domain of unknown function (DUF309)
K8Z39_10590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z39_10600	COG2188	Transcriptional regulator
K8Z39_10610	COG3711	transcriptional antiterminator
K8Z39_10615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_10615	COG1263	PTS System
K8Z39_10615	COG2190	(PTS) system
K8Z39_10640	COG0778	Nitroreductase
K8Z39_10645	COG2199	diguanylate cyclase activity
K8Z39_10655	COG2084	Dehydrogenase
K8Z39_10690	COG0436	Aminotransferase
K8Z39_10695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z39_10715	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_10720	COG1695	Transcriptional regulator
K8Z39_10750	COG0183	Belongs to the thiolase family
K8Z39_10785	COG3842	ATPase activity
K8Z39_10790	COG0366	Alpha amylase catalytic
K8Z39_10800	COG2182	Extracellular solute-binding protein
K8Z39_10805	COG1175	transmembrane transport
K8Z39_10810	COG3833	ABC-type maltose transport systems, permease component
K8Z39_10815	COG1609	Transcriptional regulator
K8Z39_10820	COG0436	Aminotransferase
K8Z39_10830	COG2205	protein histidine kinase activity
K8Z39_10840	COG3209	COG3209 Rhs family protein
K8Z39_10860	COG2814	Major facilitator Superfamily
K8Z39_10905	COG1408	metallophosphoesterase
K8Z39_10910	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_10915	COG2200	EAL domain
K8Z39_10930	COG4703	Protein of unknown function (DUF1797)
K8Z39_10940	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z39_10950	COG0517	IMP dehydrogenase activity
K8Z39_10955	COG0583	DNA-binding transcription factor activity
K8Z39_10975	COG0569	domain protein
K8Z39_10980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z39_10990	COG0561	phosphatase activity
K8Z39_11005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z39_11010	COG0022	dehydrogenase e1 component
K8Z39_11060	COG1982	Orn Lys Arg decarboxylase major
K8Z39_11080	COG0483	inositol monophosphate 1-phosphatase activity
K8Z39_11090	COG1217	gtp-binding protein TYPA
K8Z39_11105	COG4896	Protein conserved in bacteria
K8Z39_11115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z39_11120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z39_11130	COG0772	Belongs to the SEDS family
K8Z39_11135	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z39_11170	COG3336	cytochrome c oxidase
K8Z39_11185	COG2340	Cysteine-rich secretory protein family
K8Z39_11200	COG0406	alpha-ribazole phosphatase activity
K8Z39_11205	COG3679	Belongs to the UPF0342 family
K8Z39_11220	COG0742	ribosomal rna small subunit methyltransferase
K8Z39_11230	COG3314	Sporulation integral membrane protein YlbJ
K8Z39_11235	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z39_11240	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z39_11250	COG0582	viral genome integration into host DNA
K8Z39_11290	COG1396	sequence-specific DNA binding
K8Z39_11330	COG2002	toxin-antitoxin pair type II binding
K8Z39_11385	COG0582	viral genome integration into host DNA
K8Z39_11440	COG0740	serine-type endopeptidase activity
K8Z39_11515	COG4824	toxin secretion phage lysis holin
K8Z39_11550	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z39_11555	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z39_11575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z39_11595	COG0768	penicillin binding
K8Z39_11600	COG0768	penicillin binding
K8Z39_11620	COG0772	Belongs to the SEDS family
K8Z39_11640	COG0849	cell division
K8Z39_11645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z39_11655	COG1191	sigma factor activity
K8Z39_11660	COG1191	sigma factor activity
K8Z39_11665	COG1873	PFAM PRC-barrel domain
K8Z39_11675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z39_11685	COG0762	integral membrane protein
K8Z39_11690	COG2302	S4 RNA-binding domain
K8Z39_11695	COG3599	regulation of cell shape
K8Z39_11715	COG0564	pseudouridine synthase activity
K8Z39_11775	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z39_11790	COG0006	proline dipeptidase activity
K8Z39_11800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z39_11805	COG1561	YicC-like family, N-terminal region
K8Z39_11825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z39_11830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z39_11845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z39_11845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z39_11855	COG0631	protein serine/threonine phosphatase activity
K8Z39_11860	COG0515	serine threonine protein kinase
K8Z39_11860	COG2815	serine threonine protein kinase
K8Z39_11870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z39_11875	COG1564	THIamine pyrophosphokinase
K8Z39_11890	COG1302	Protein conserved in bacteria
K8Z39_11895	COG1461	Dihydroxyacetone kinase
K8Z39_11900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z39_11915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z39_11920	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_11925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z39_11935	COG1196	nuclear chromosome segregation
K8Z39_11940	COG0552	protein localization to endoplasmic reticulum
K8Z39_11950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z39_11960	COG1837	Belongs to the UPF0109 family
K8Z39_12000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z39_12005	COG0758	DNA mediated transformation
K8Z39_12010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z39_12020	COG4974	Belongs to the 'phage' integrase family
K8Z39_12070	COG4589	Belongs to the CDS family
K8Z39_12080	COG0750	zinc metalloprotease
K8Z39_12100	COG0195	Participates in both transcription termination and antitermination
K8Z39_12105	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z39_12110	COG1358	cellular component organization or biogenesis
K8Z39_12120	COG1550	Protein conserved in bacteria
K8Z39_12125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z39_12135	COG0196	riboflavin kinase activity
K8Z39_12150	COG0726	polysaccharide deacetylase
K8Z39_12155	COG0612	Peptidase, M16
K8Z39_12160	COG1873	PFAM PRC-barrel domain
K8Z39_12165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z39_12170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z39_12175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z39_12180	COG0527	aspartate kinase activity
K8Z39_12190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z39_12200	COG0740	serine-type endopeptidase activity
K8Z39_12215	COG2188	Transcriptional regulator
K8Z39_12220	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z39_12225	COG3845	ABC transporter
K8Z39_12230	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z39_12235	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z39_12240	COG0612	Peptidase, M16
K8Z39_12245	COG0612	Peptidase, M16
K8Z39_12250	COG0300	oxidoreductase activity
K8Z39_12265	COG1426	Protein conserved in bacteria
K8Z39_12270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z39_12290	COG1692	metallophosphoesterase
K8Z39_12295	COG2359	stage V sporulation protein S
K8Z39_12305	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z39_12305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z39_12310	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z39_12320	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z39_12345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z39_12350	COG1368	sulfuric ester hydrolase activity
K8Z39_12360	COG3773	Cell wall hydrolase
K8Z39_12365	COG1404	Belongs to the peptidase S8 family
K8Z39_12370	COG0823	Involved in the tonB-independent uptake of proteins
K8Z39_12375	COG2723	6-phospho-beta-galactosidase activity
K8Z39_12380	COG2188	Transcriptional regulator
K8Z39_12390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_12400	COG1346	cytolysis
K8Z39_12420	COG1086	Polysaccharide biosynthesis protein
K8Z39_12440	COG3300	MHYT domain
K8Z39_12440	COG5001	Diguanylate cyclase
K8Z39_12445	COG2267	carboxylic ester hydrolase activity
K8Z39_12465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z39_12470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z39_12475	COG2169	Transcriptional regulator
K8Z39_12485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_12490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_12495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_12500	COG1120	ATPase activity
K8Z39_12505	COG2819	hydrolase of the alpha beta superfamily
K8Z39_12515	COG1937	Protein conserved in bacteria
K8Z39_12520	COG2608	mercury ion transmembrane transporter activity
K8Z39_12525	COG2217	Heavy metal translocating P-type atpase
K8Z39_12540	COG2116	formate transmembrane transporter activity
K8Z39_12555	COG1113	amino acid transport
K8Z39_12565	COG2322	membrane
K8Z39_12570	COG1979	alcohol dehydrogenase
K8Z39_12575	COG1349	DNA-binding transcription factor activity
K8Z39_12580	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z39_12585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z39_12585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z39_12585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z39_12595	COG1388	LysM domain
K8Z39_12595	COG3584	3D domain protein
K8Z39_12625	COG0464	growth
K8Z39_12635	COG2860	membrane
K8Z39_12640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z39_12645	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z39_12650	COG0789	Transcriptional regulator
K8Z39_12655	COG0174	glutamine synthetase
K8Z39_12665	COG1695	Transcriptional regulator
K8Z39_12685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z39_12710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_12745	COG1132	(ABC) transporter
K8Z39_12750	COG1132	(ABC) transporter
K8Z39_12775	COG0730	response to heat
K8Z39_12790	COG1346	cytolysis
K8Z39_12800	COG0583	DNA-binding transcription factor activity
K8Z39_12815	COG1131	(ABC) transporter
K8Z39_12830	COG1473	amidohydrolase
K8Z39_12840	COG0785	Cytochrome C biogenesis protein
K8Z39_12845	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z39_12870	COG2226	methyltransferase
K8Z39_12895	COG0010	Belongs to the arginase family
K8Z39_12900	COG1329	Transcriptional regulator
K8Z39_12905	COG1902	pentaerythritol trinitrate reductase activity
K8Z39_12910	COG0069	glutamate synthase activity
K8Z39_12920	COG0346	lactoylglutathione lyase activity
K8Z39_12925	COG0400	carboxylic ester hydrolase activity
K8Z39_12930	COG5002	protein histidine kinase activity
K8Z39_12940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_12980	COG0830	nickel cation binding
K8Z39_13000	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K8Z39_13030	COG1396	sequence-specific DNA binding
K8Z39_13035	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_13040	COG1268	BioY protein
K8Z39_13045	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_13050	COG0183	Belongs to the thiolase family
K8Z39_13065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z39_13075	COG2211	Major facilitator Superfamily
K8Z39_13105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z39_13110	COG1132	(ABC) transporter
K8Z39_13125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_13160	COG0824	Thioesterase
K8Z39_13165	COG4841	protein insertion into membrane
K8Z39_13175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K8Z39_13175	COG1328	CTP reductase activity
K8Z39_13185	COG0745	RESPONSE REGULATOR receiver
K8Z39_13190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z39_13195	COG1832	CoA-binding protein
K8Z39_13200	COG0187	DNA topoisomerase II activity
K8Z39_13205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z39_13210	COG0673	inositol 2-dehydrogenase activity
K8Z39_13230	COG1131	(ABC) transporter
K8Z39_13240	COG1595	DNA-templated transcription, initiation
K8Z39_13250	COG1316	TRANSCRIPTIONal
K8Z39_13255	COG4166	transmembrane transport
K8Z39_13260	COG4166	transmembrane transport
K8Z39_13265	COG4166	transmembrane transport
K8Z39_13270	COG2226	methyltransferase
K8Z39_13305	COG0531	amino acid
K8Z39_13320	COG0697	spore germination
K8Z39_13325	COG3383	formate dehydrogenase (NAD+) activity
K8Z39_13330	COG2427	Protein of unknown function (DUF1641)
K8Z39_13335	COG5609	conserved protein (DUF2294)
K8Z39_13340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z39_13350	COG2116	formate transmembrane transporter activity
K8Z39_13355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_13360	COG0303	'Molybdopterin
K8Z39_13365	COG0314	molybdopterin synthase activity
K8Z39_13375	COG0489	protein tyrosine kinase activity
K8Z39_13390	COG3326	Membrane
K8Z39_13395	COG2962	Rard protein
K8Z39_13400	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z39_13405	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z39_13415	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_13420	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_13430	COG4145	pantothenate transmembrane transporter activity
K8Z39_13445	COG0165	Argininosuccinate lyase
K8Z39_13455	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_13490	COG0716	FMN binding
K8Z39_13525	COG2720	vancomycin resistance protein
K8Z39_13530	COG2514	catechol 2,3-dioxygenase activity
K8Z39_13540	COG1285	pathogenesis
K8Z39_13550	COG3852	Histidine kinase
K8Z39_13575	COG0488	(ABC) transporter
K8Z39_13605	COG1404	Belongs to the peptidase S8 family
K8Z39_13640	COG0457	Tetratricopeptide repeat
K8Z39_13650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_13660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z39_13690	COG0697	spore germination
K8Z39_13700	COG3397	chitin binding
K8Z39_13705	COG0823	Involved in the tonB-independent uptake of proteins
K8Z39_13715	COG1252	NADH dehydrogenase
K8Z39_13720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_13720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_13725	COG1183	phosphatidylcholine synthase activity
K8Z39_13750	COG0277	FAD linked oxidase domain protein
K8Z39_13755	COG0385	Bile acid
K8Z39_13765	COG0457	Tetratricopeptide repeat
K8Z39_13775	COG0604	alcohol dehydrogenase
K8Z39_13780	COG0640	Transcriptional regulator
K8Z39_13790	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_13820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_13850	COG1164	Oligoendopeptidase f
K8Z39_13855	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_13865	COG1193	negative regulation of DNA recombination
K8Z39_13880	COG2890	protein-(glutamine-N5) methyltransferase activity
K8Z39_13890	COG0583	DNA-binding transcription factor activity
K8Z39_13905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_13930	COG3739	integral membrane protein
K8Z39_13935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_13940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_13945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_13950	COG1247	-acetyltransferase
K8Z39_13960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z39_13965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z39_14000	COG2814	Major facilitator Superfamily
K8Z39_14005	COG1113	amino acid transport
K8Z39_14070	COG1151	hydroxylamine reductase activity
K8Z39_14125	COG1191	sigma factor activity
K8Z39_14150	COG1733	regulation of RNA biosynthetic process
K8Z39_14155	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z39_14160	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_14180	COG0384	phenazine biosynthesis protein PhzF
K8Z39_14200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_14220	COG0673	inositol 2-dehydrogenase activity
K8Z39_14225	COG2188	Transcriptional regulator
K8Z39_14255	COG0814	amino acid
K8Z39_14270	COG1733	regulation of RNA biosynthetic process
K8Z39_14275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z39_14275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z39_14280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_14280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z39_14290	COG0840	transmembrane signaling receptor activity
K8Z39_14320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z39_14325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z39_14330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z39_14335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z39_14345	COG1070	Carbohydrate kinase
K8Z39_14350	COG2706	6-phosphogluconolactonase activity
K8Z39_14355	COG3813	Protein conserved in bacteria
K8Z39_14360	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z39_14370	COG0697	spore germination
K8Z39_14400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z39_14410	COG0789	Transcriptional regulator
K8Z39_14415	COG1253	flavin adenine dinucleotide binding
K8Z39_14445	COG0477	Major facilitator Superfamily
K8Z39_14455	COG0500	methyltransferase
K8Z39_14480	COG0628	permease
K8Z39_14515	COG2365	Tyrosine phosphatase family
K8Z39_14525	COG1011	Hydrolase
K8Z39_14550	COG1131	(ABC) transporter
K8Z39_14560	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_14580	COG0469	pyruvate kinase activity
K8Z39_14590	COG0778	Nitroreductase
K8Z39_14595	COG1733	regulation of RNA biosynthetic process
K8Z39_14605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z39_14625	COG1288	antiporter activity
K8Z39_14680	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z39_14690	COG2031	fatty acid transporter
K8Z39_14705	COG2814	Major facilitator Superfamily
K8Z39_14710	COG1846	Transcriptional regulator
K8Z39_14725	COG0477	Major facilitator Superfamily
K8Z39_14735	COG2843	Capsule synthesis protein
K8Z39_14740	COG1876	peptidase activity
K8Z39_14765	COG5444	nuclease activity
K8Z39_14845	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_14845	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_14860	COG3831	ATPase activity
K8Z39_14890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z39_14920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_14930	COG3850	Histidine kinase
K8Z39_14930	COG5002	protein histidine kinase activity
K8Z39_14935	COG0577	efflux transmembrane transporter activity
K8Z39_14955	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z39_14965	COG1690	Belongs to the RtcB family
K8Z39_14975	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z39_14990	COG2814	Major facilitator Superfamily
K8Z39_15085	COG0346	lactoylglutathione lyase activity
K8Z39_15105	COG1522	sequence-specific DNA binding
K8Z39_15110	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_15115	COG1309	transcriptional regulator
K8Z39_15120	COG2814	Major facilitator Superfamily
K8Z39_15125	COG0640	Transcriptional regulator
K8Z39_15130	COG0346	lactoylglutathione lyase activity
K8Z39_15135	COG0798	PFAM Bile acid sodium symporter
K8Z39_15145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_15155	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z39_15160	COG0456	acetyltransferase
K8Z39_15170	COG5609	conserved protein (DUF2294)
K8Z39_15175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z39_15185	COG0288	reversible hydration of carbon dioxide
K8Z39_15190	COG0657	acetylesterase activity
K8Z39_15260	COG0598	Magnesium transport protein CorA
K8Z39_15295	COG2814	Major facilitator Superfamily
K8Z39_15305	COG0583	DNA-binding transcription factor activity
K8Z39_15310	COG2801	Transposase and inactivated derivatives
K8Z39_15335	COG1335	isochorismatase
K8Z39_15340	COG2267	carboxylic ester hydrolase activity
K8Z39_15345	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_15365	COG2207	Transcriptional regulator
K8Z39_15390	COG5002	protein histidine kinase activity
K8Z39_15395	COG1063	alcohol dehydrogenase
K8Z39_15415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_15420	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_15425	COG1522	sequence-specific DNA binding
K8Z39_15445	COG3848	Pyruvate phosphate dikinase
K8Z39_15445	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z39_15470	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z39_15480	COG0454	-acetyltransferase
K8Z39_15490	COG3314	Sporulation integral membrane protein YlbJ
K8Z39_15505	COG1960	acyl-CoA dehydrogenase activity
K8Z39_15515	COG0640	Transcriptional regulator
K8Z39_15520	COG3142	Participates in the control of copper homeostasis
K8Z39_15530	COG1414	Transcriptional regulator
K8Z39_15535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z39_15540	COG1984	allophanate hydrolase subunit 2
K8Z39_15575	COG0768	penicillin binding
K8Z39_15620	COG0833	amino acid
K8Z39_15630	COG0730	response to heat
K8Z39_15670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_15675	COG0697	spore germination
K8Z39_15690	COG0456	acetyltransferase
K8Z39_15700	COG0037	tRNA processing
K8Z39_15700	COG0590	tRNA wobble adenosine to inosine editing
K8Z39_15725	COG3831	ATPase activity
K8Z39_15725	COG4884	unkown
K8Z39_15745	COG1846	Transcriptional regulator
K8Z39_15750	COG0778	Nitroreductase
K8Z39_15840	COG0714	Associated with various cellular activities
K8Z39_15880	COG0753	catalase activity
K8Z39_15885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z39_15905	COG0463	Glycosyl transferase, family 2
K8Z39_15950	COG0714	Associated with various cellular activities
K8Z39_15970	COG0346	lactoylglutathione lyase activity
K8Z39_15975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_15995	COG3655	Transcriptional regulator
K8Z39_16005	COG1785	Belongs to the alkaline phosphatase family
K8Z39_16010	COG2720	vancomycin resistance protein
K8Z39_16020	COG3239	Fatty acid desaturase
K8Z39_16030	COG0833	amino acid
K8Z39_16035	COG1414	Transcriptional regulator
K8Z39_16040	COG4187	Peptidase family M20/M25/M40
K8Z39_16045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z39_16065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_16085	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_16110	COG1070	Carbohydrate kinase
K8Z39_16115	COG2390	Transcriptional regulator
K8Z39_16125	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z39_16135	COG1879	ABC-type sugar transport system periplasmic component
K8Z39_16150	COG0277	FAD linked oxidase domain protein
K8Z39_16165	COG1388	LysM domain
K8Z39_16165	COG3584	3D domain protein
K8Z39_16210	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z39_16210	COG1605	Chorismate mutase
K8Z39_16225	COG0287	Prephenate dehydrogenase
K8Z39_16240	COG1309	transcriptional regulator
K8Z39_16245	COG1033	growth of symbiont in host cell
K8Z39_16245	COG2409	Drug exporters of the RND superfamily
K8Z39_16260	COG0488	(ABC) transporter
K8Z39_16265	COG1368	sulfuric ester hydrolase activity
K8Z39_16275	COG0861	Integral membrane protein TerC family
K8Z39_16285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_16290	COG0346	lactoylglutathione lyase activity
K8Z39_16295	COG4912	Dna alkylation repair
K8Z39_16320	COG0697	spore germination
K8Z39_16340	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z39_16370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z39_16375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_16380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z39_16395	COG0628	permease
K8Z39_16445	COG1131	(ABC) transporter
K8Z39_16460	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8Z39_16470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z39_16475	COG0436	Aminotransferase
K8Z39_16510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K8Z39_16525	COG2261	transglycosylase associated protein
K8Z39_16550	COG0477	Major facilitator Superfamily
K8Z39_16550	COG2814	Major facilitator Superfamily
K8Z39_16555	COG4533	DNA binding
K8Z39_16560	COG0789	Transcriptional regulator
K8Z39_16565	COG1664	Polymer-forming cytoskeletal
K8Z39_16575	COG2814	Major facilitator Superfamily
K8Z39_16620	COG1307	EDD domain protein, DegV family
K8Z39_16625	COG1164	Oligoendopeptidase f
K8Z39_16635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z39_16655	COG0745	RESPONSE REGULATOR receiver
K8Z39_16660	COG3850	Histidine kinase
K8Z39_16660	COG5002	protein histidine kinase activity
K8Z39_16705	COG0667	Aldo Keto reductase
K8Z39_16720	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z39_16730	COG4166	transmembrane transport
K8Z39_16740	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z39_16750	COG0586	Pfam SNARE associated Golgi protein
K8Z39_16790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_16795	COG3938	Belongs to the proline racemase family
K8Z39_16805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z39_16810	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_16815	COG1115	amino acid carrier protein
K8Z39_16820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z39_16825	COG1162	GTPase activity
K8Z39_16840	COG3397	chitin binding
K8Z39_16855	COG4637	Psort location Cytoplasmic, score
K8Z39_16890	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z39_16895	COG2105	PFAM AIG2 family protein
K8Z39_16905	COG3973	AAA domain
K8Z39_16910	COG0456	acetyltransferase
K8Z39_16955	COG2315	Protein conserved in bacteria
K8Z39_16960	COG2226	methyltransferase
K8Z39_16965	COG2205	protein histidine kinase activity
K8Z39_16985	COG1819	glycosyl
K8Z39_16990	COG3397	chitin binding
K8Z39_16995	COG2153	protein acetylation
K8Z39_17025	COG0517	IMP dehydrogenase activity
K8Z39_17025	COG4175	Glycine betaine
K8Z39_17030	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z39_17070	COG0456	acetyltransferase
K8Z39_17070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z39_17075	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_17085	COG2814	Major facilitator Superfamily
K8Z39_17095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z39_17100	COG0022	dehydrogenase e1 component
K8Z39_17105	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z39_17110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z39_17125	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_17160	COG3284	Transcriptional regulator
K8Z39_17190	COG1309	transcriptional regulator
K8Z39_17230	COG2959	enzyme of heme biosynthesis
K8Z39_17245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_17280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_17285	COG0697	spore germination
K8Z39_17290	COG0201	protein transport
K8Z39_17305	COG0737	Belongs to the 5'-nucleotidase family
K8Z39_17310	COG3227	Zinc metalloprotease (Elastase)
K8Z39_17315	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z39_17330	COG0076	glutamate decarboxylase activity
K8Z39_17335	COG0657	acetylesterase activity
K8Z39_17340	COG1073	alpha beta
K8Z39_17345	COG0577	efflux transmembrane transporter activity
K8Z39_17350	COG1136	(ABC) transporter
K8Z39_17365	COG5002	protein histidine kinase activity
K8Z39_17370	COG0745	RESPONSE REGULATOR receiver
K8Z39_17375	COG1011	Hydrolase
K8Z39_17405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_17425	COG0322	excinuclease ABC activity
K8Z39_17465	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z39_17485	COG3878	Protein conserved in bacteria
K8Z39_17520	COG0592	DNA-directed DNA polymerase activity
K8Z39_17535	COG2223	nitrite transmembrane transporter activity
K8Z39_17545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_17580	COG0697	spore germination
K8Z39_17585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_17600	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z39_17615	COG2814	Major facilitator Superfamily
K8Z39_17620	COG2814	Major facilitator Superfamily
K8Z39_17675	COG0768	penicillin binding
K8Z39_17680	COG0671	phosphoesterase, PA-phosphatase related
K8Z39_17685	COG0604	alcohol dehydrogenase
K8Z39_17690	COG5002	protein histidine kinase activity
K8Z39_17695	COG0745	RESPONSE REGULATOR receiver
K8Z39_17705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z39_17720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z39_17765	COG0582	viral genome integration into host DNA
K8Z39_17770	COG2205	protein histidine kinase activity
K8Z39_17795	COG1794	racemase activity, acting on amino acids and derivatives
K8Z39_17800	COG1819	glycosyl
K8Z39_17810	COG0768	penicillin binding
K8Z39_17815	COG5002	protein histidine kinase activity
K8Z39_17820	COG0561	phosphatase activity
K8Z39_17855	COG2124	cytochrome p450
K8Z39_17925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z39_17935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_17940	COG0460	homoserine dehydrogenase
K8Z39_17960	COG0577	efflux transmembrane transporter activity
K8Z39_17965	COG1136	(ABC) transporter
K8Z39_17975	COG0488	(ABC) transporter
K8Z39_17980	COG2205	protein histidine kinase activity
K8Z39_17985	COG0745	RESPONSE REGULATOR receiver
K8Z39_17995	COG3773	Cell wall hydrolase
K8Z39_18000	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z39_18010	COG3386	PFAM SMP-30 Gluconolaconase
K8Z39_18020	COG0693	protein deglycase activity
K8Z39_18025	COG2323	membrane
K8Z39_18050	COG2368	4-hydroxyphenylacetate
K8Z39_18055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_18085	COG1131	(ABC) transporter
K8Z39_18095	COG0583	DNA-binding transcription factor activity
K8Z39_18100	COG1942	4-Oxalocrotonate Tautomerase
K8Z39_18145	COG2207	Transcriptional regulator
K8Z39_18150	COG3227	Zinc metalloprotease (Elastase)
K8Z39_18165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z39_18190	COG1686	Belongs to the peptidase S11 family
K8Z39_18210	COG0572	uridine kinase
K8Z39_18240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z39_18245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z39_18250	COG1024	Enoyl-CoA hydratase
K8Z39_18255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z39_18260	COG0511	ligase activity, forming carbon-carbon bonds
K8Z39_18265	COG0439	Biotin carboxylase
K8Z39_18270	COG1960	acyl-CoA dehydrogenase activity
K8Z39_18285	COG1309	transcriptional regulator
K8Z39_18325	COG4824	toxin secretion phage lysis holin
K8Z39_18400	COG0740	serine-type endopeptidase activity
K8Z39_18455	COG0582	viral genome integration into host DNA
K8Z39_18510	COG2002	toxin-antitoxin pair type II binding
K8Z39_18525	COG1484	DNA-dependent DNA replication
K8Z39_18555	COG3620	sequence-specific DNA binding
K8Z39_18565	COG0582	viral genome integration into host DNA
K8Z39_18575	COG1131	(ABC) transporter
K8Z39_18590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_18605	COG0768	penicillin binding
K8Z39_18610	COG0768	penicillin binding
K8Z39_18620	COG1595	DNA-templated transcription, initiation
K8Z39_18625	COG0768	penicillin binding
K8Z39_18635	COG2239	Acts as a magnesium transporter
K8Z39_18640	COG0772	Belongs to the SEDS family
K8Z39_18675	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z39_18685	COG0076	glutamate decarboxylase activity
K8Z39_18695	COG1533	DNA photolyase activity
K8Z39_18715	COG0814	amino acid
K8Z39_18720	COG1760	l-serine dehydratase
K8Z39_18725	COG1760	l-serine dehydratase
K8Z39_18745	COG0367	asparagine synthase
K8Z39_18750	COG1309	transcriptional regulator
K8Z39_18770	COG1396	sequence-specific DNA binding
K8Z39_18880	COG2239	Acts as a magnesium transporter
K8Z39_18885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_18890	COG0741	lytic transglycosylase activity
K8Z39_18955	COG2814	Major facilitator Superfamily
K8Z39_18970	COG1686	Belongs to the peptidase S11 family
K8Z39_18975	COG0110	maltose O-acetyltransferase activity
K8Z39_18980	COG0730	response to heat
K8Z39_18990	COG2002	toxin-antitoxin pair type II binding
K8Z39_19015	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z39_19045	COG1846	Transcriptional regulator
K8Z39_19050	COG3961	Belongs to the TPP enzyme family
K8Z39_19055	COG2226	methyltransferase
K8Z39_19065	COG0500	methyltransferase
K8Z39_19065	COG3615	Tellurite resistance protein tehB
K8Z39_19090	COG1309	transcriptional regulator
K8Z39_19110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_19130	COG1846	Transcriptional regulator
K8Z39_19150	COG2971	BadF BadG BcrA BcrD
K8Z39_19175	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z39_19200	COG1595	DNA-templated transcription, initiation
K8Z39_19205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z39_19275	COG1396	sequence-specific DNA binding
K8Z39_19305	COG1132	(ABC) transporter
K8Z39_19310	COG1132	(ABC) transporter
K8Z39_19325	COG2258	MOSC domain
K8Z39_19330	COG0583	DNA-binding transcription factor activity
K8Z39_19350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z39_19355	COG0583	DNA-binding transcription factor activity
K8Z39_19390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_19400	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z39_19425	COG1247	-acetyltransferase
K8Z39_19460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_19485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_19525	COG0028	Belongs to the TPP enzyme family
K8Z39_19540	COG1136	(ABC) transporter
K8Z39_19545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z39_19550	COG1187	pseudouridine synthase activity
K8Z39_19555	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_19570	COG1115	amino acid carrier protein
K8Z39_19580	COG2318	DinB family
K8Z39_19590	COG0776	regulation of translation
K8Z39_19605	COG2814	Major facilitator Superfamily
K8Z39_19610	COG3251	PFAM MbtH domain protein
K8Z39_19615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_19620	COG1535	isochorismatase
K8Z39_19620	COG3433	isochorismatase activity
K8Z39_19625	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z39_19630	COG1169	isochorismate synthase
K8Z39_19635	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_19640	COG2223	nitrite transmembrane transporter activity
K8Z39_19660	COG0419	ATPase involved in DNA repair
K8Z39_19665	COG0420	3'-5' exonuclease activity
K8Z39_19680	COG1024	Enoyl-CoA hydratase
K8Z39_19685	COG1280	lysine exporter protein (LysE YggA)
K8Z39_19695	COG2084	Dehydrogenase
K8Z39_19700	COG1960	acyl-CoA dehydrogenase activity
K8Z39_19705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z39_19710	COG2079	MmgE PrpD family protein
K8Z39_19715	COG0372	Belongs to the citrate synthase family
K8Z39_19720	COG4841	protein insertion into membrane
K8Z39_19725	COG2814	Major facilitator Superfamily
K8Z39_19735	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z39_19735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_19755	COG0300	oxidoreductase activity
K8Z39_19835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_19840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z39_19845	COG0671	phosphoesterase, PA-phosphatase related
K8Z39_19855	COG0515	serine threonine protein kinase
K8Z39_19855	COG4991	sh3 domain protein
K8Z39_19855	COG3064	Membrane
K8Z39_19890	COG1509	lysine 2,3-aminomutase activity
K8Z39_19895	COG3829	transcription factor binding
K8Z39_19900	COG0456	acetyltransferase
K8Z39_19905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z39_19910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z39_19915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z39_19920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z39_19935	COG5506	Protein of unknown function (DUF1694)
K8Z39_19940	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_19945	COG1253	flavin adenine dinucleotide binding
K8Z39_19980	COG1174	glycine betaine transport
K8Z39_19985	COG1125	glycine betaine transport
K8Z39_19985	COG0517	IMP dehydrogenase activity
K8Z39_20020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z39_20045	COG1064	alcohol dehydrogenase
K8Z39_20050	COG0384	phenazine biosynthesis protein PhzF
K8Z39_20055	COG1737	Transcriptional regulator
K8Z39_20060	COG2197	response regulator
K8Z39_20065	COG4585	Histidine kinase
K8Z39_20065	COG2203	Gaf domain
K8Z39_20070	COG0668	transmembrane transport
K8Z39_20085	COG1335	isochorismatase
K8Z39_20105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_20110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_20115	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_20130	COG0367	asparagine synthase
K8Z39_20135	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z39_20140	COG1999	signal sequence binding
K8Z39_20150	COG1307	EDD domain protein, DegV family
K8Z39_20160	COG0805	protein transport
K8Z39_20170	COG1272	protein, Hemolysin III
K8Z39_20180	COG0204	Acyl-transferase
K8Z39_20190	COG0768	penicillin binding
K8Z39_20205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_20220	COG0546	phosphoglycolate phosphatase activity
K8Z39_20230	COG4473	ABC transporter
K8Z39_20235	COG1131	(ABC) transporter
K8Z39_20245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z39_20250	COG3655	Transcriptional regulator
K8Z39_20260	COG0456	acetyltransferase
K8Z39_20270	COG1794	racemase activity, acting on amino acids and derivatives
K8Z39_20280	COG2610	gluconate transmembrane transporter activity
K8Z39_20310	COG0017	Asparaginyl-tRNA synthetase
K8Z39_20365	COG0018	arginyl-trna synthetase
K8Z39_20370	COG2136	Putative SAM-dependent methyltransferase
K8Z39_20370	COG2521	methyltransferase
K8Z39_20385	COG1413	lyase activity
K8Z39_20395	COG0629	single-stranded DNA binding
K8Z39_20415	COG1476	TRANSCRIPTIONal
K8Z39_20460	COG0488	(ABC) transporter
K8Z39_20465	COG1418	mRNA catabolic process
K8Z39_20480	COG0457	Tetratricopeptide repeat
K8Z39_20530	COG2359	stage V sporulation protein S
K8Z39_20565	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z39_20570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z39_20575	COG2146	nitrite reductase [NAD(P)H] activity
K8Z39_20580	COG1587	Uroporphyrinogen-III synthase
K8Z39_20580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z39_20590	COG1648	precorrin-2 dehydrogenase activity
K8Z39_20600	COG2223	nitrite transmembrane transporter activity
K8Z39_20605	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K8Z39_20610	COG0314	molybdopterin synthase activity
K8Z39_20615	COG0303	'Molybdopterin
K8Z39_20620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_20625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z39_20630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_20635	COG2181	nitrate reductase activity
K8Z39_20640	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z39_20645	COG1140	nitrate reductase beta subunit
K8Z39_20650	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z39_20655	COG0714	Associated with various cellular activities
K8Z39_20660	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z39_20670	COG0386	Belongs to the glutathione peroxidase family
K8Z39_20680	COG0426	domain, Protein
K8Z39_20680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z39_20695	COG1595	DNA-templated transcription, initiation
K8Z39_20710	COG0346	lactoylglutathione lyase activity
K8Z39_20715	COG1082	Xylose isomerase domain protein TIM barrel
K8Z39_20740	COG2226	methyltransferase
K8Z39_20765	COG3874	Sporulation protein YtfJ
K8Z39_20830	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z39_20865	COG0456	acetyltransferase
K8Z39_20895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_20900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_20905	COG1819	glycosyl
K8Z39_20920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z39_20935	COG0561	phosphatase activity
K8Z39_20945	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_20960	COG2211	Major facilitator Superfamily
K8Z39_20975	COG1876	peptidase activity
K8Z39_20985	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z39_21005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z39_21010	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_21030	COG1253	flavin adenine dinucleotide binding
K8Z39_21035	COG2839	Protein conserved in bacteria
K8Z39_21040	COG0702	epimerase
K8Z39_21055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_21065	COG1607	acyl-coa hydrolase
K8Z39_21070	COG3689	TIGRFAM TIGR03943 family protein
K8Z39_21075	COG0701	Predicted permease
K8Z39_21090	COG0586	Pfam SNARE associated Golgi protein
K8Z39_21095	COG1051	belongs to the nudix hydrolase family
K8Z39_21100	COG5337	Spore coat protein CotH
K8Z39_21125	COG4166	transmembrane transport
K8Z39_21135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z39_21145	COG0702	epimerase
K8Z39_21155	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z39_21160	COG0456	acetyltransferase
K8Z39_21165	COG0523	cobalamin synthesis protein
K8Z39_21175	COG4989	oxidoreductase activity
K8Z39_21180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_21185	COG1231	oxidoreductase activity
K8Z39_21195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z39_21210	COG0783	Belongs to the Dps family
K8Z39_21215	COG3949	Membrane
K8Z39_21230	COG0840	transmembrane signaling receptor activity
K8Z39_21255	COG3152	Membrane
K8Z39_21260	COG2814	Major facilitator Superfamily
K8Z39_21265	COG0667	Aldo Keto reductase
K8Z39_21270	COG0640	Transcriptional regulator
K8Z39_21275	COG1404	Belongs to the peptidase S8 family
K8Z39_21280	COG2002	toxin-antitoxin pair type II binding
K8Z39_21285	COG0577	efflux transmembrane transporter activity
K8Z39_21320	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z39_21330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_21335	COG1279	arginine transmembrane transporter activity
K8Z39_21340	COG2814	Major facilitator Superfamily
K8Z39_21350	COG1082	Xylose isomerase domain protein TIM barrel
K8Z39_21360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z39_21385	COG1247	-acetyltransferase
K8Z39_21390	COG1285	pathogenesis
K8Z39_21405	COG5002	protein histidine kinase activity
K8Z39_21410	COG0745	RESPONSE REGULATOR receiver
K8Z39_21425	COG1316	TRANSCRIPTIONal
K8Z39_21450	COG0460	homoserine dehydrogenase
K8Z39_21480	COG0300	oxidoreductase activity
K8Z39_21485	COG5002	protein histidine kinase activity
K8Z39_21490	COG0745	RESPONSE REGULATOR receiver
K8Z39_21495	COG1132	(ABC) transporter
K8Z39_21505	COG0791	NLP P60 protein
K8Z39_21505	COG1388	LysM domain
K8Z39_21520	COG1686	Belongs to the peptidase S11 family
K8Z39_21560	COG1216	Glycosyl transferase, family 2
K8Z39_21570	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z39_21575	COG4988	ABC transporter
K8Z39_21580	COG1294	oxidase, subunit
K8Z39_21585	COG1271	oxidase subunit
K8Z39_21625	COG0583	DNA-binding transcription factor activity
K8Z39_21645	COG0411	ABC transporter
K8Z39_21655	COG0523	cobalamin synthesis protein
K8Z39_21660	COG1231	oxidoreductase activity
K8Z39_21670	COG0628	permease
K8Z39_21680	COG0778	Nitroreductase
K8Z39_21685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z39_21690	COG1959	2 iron, 2 sulfur cluster binding
K8Z39_21695	COG0583	DNA-binding transcription factor activity
K8Z39_21700	COG0697	spore germination
K8Z39_21710	COG4549	nuclear export factor GLE1
K8Z39_21715	COG2372	response to copper ion
K8Z39_21715	COG1276	copper resistance
K8Z39_21730	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_21750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z39_21760	COG2132	Multicopper oxidase
K8Z39_21770	COG0006	proline dipeptidase activity
K8Z39_21780	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z39_21795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z39_21800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_21810	COG2390	Transcriptional regulator
K8Z39_21815	COG1309	transcriptional regulator
K8Z39_21850	COG0531	amino acid
K8Z39_21855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z39_21870	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z39_21875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_21880	COG4166	transmembrane transport
K8Z39_21900	COG0427	acetyl-CoA hydrolase
K8Z39_21905	COG3279	Response regulator of the LytR AlgR family
K8Z39_21915	COG3384	dioxygenase
K8Z39_21920	COG2814	Major facilitator Superfamily
K8Z39_21945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z39_21965	COG0028	Belongs to the TPP enzyme family
K8Z39_21970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_21980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z39_22000	COG2323	membrane
K8Z39_22005	COG5566	PFAM Mor transcription activator
K8Z39_22010	COG0733	neurotransmitter:sodium symporter activity
K8Z39_22030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z39_22035	COG2223	nitrite transmembrane transporter activity
K8Z39_22040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z39_22050	COG0477	Major facilitator Superfamily
K8Z39_22060	COG1695	Transcriptional regulator
K8Z39_22110	COG3620	sequence-specific DNA binding
K8Z39_22125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z39_22130	COG0784	Response regulator, receiver
K8Z39_22135	COG4191	Histidine kinase
K8Z39_22140	COG0281	malic enzyme
K8Z39_22145	COG1027	Aspartate ammonia-lyase
K8Z39_22155	COG0528	UMP kinase activity
K8Z39_22160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_22180	COG1131	(ABC) transporter
K8Z39_22215	COG2733	membrane
K8Z39_22235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z39_22260	COG3340	Belongs to the peptidase S51 family
K8Z39_22265	COG0534	Mate efflux family protein
K8Z39_22295	COG0789	Transcriptional regulator
K8Z39_22300	COG1757	Na H antiporter
K8Z39_22315	COG0701	Predicted permease
K8Z39_22320	COG0523	cobalamin synthesis protein
K8Z39_22330	COG0697	spore germination
K8Z39_22335	COG1802	Transcriptional regulator
K8Z39_22365	COG0367	asparagine synthase
K8Z39_22395	COG0406	alpha-ribazole phosphatase activity
K8Z39_22400	COG1686	Belongs to the peptidase S11 family
K8Z39_22440	COG3842	ATPase activity
K8Z39_22445	COG0583	DNA-binding transcription factor activity
K8Z39_22470	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_22505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z39_22510	COG4786	Flagellar basal body rod
K8Z39_22515	COG1419	protein localization to endoplasmic reticulum
K8Z39_22520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z39_22525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z39_22535	COG1987	bacterial-type flagellum assembly
K8Z39_22540	COG1338	Plays a role in the flagellum-specific transport system
K8Z39_22550	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_22550	COG1776	CheC inhibitor of MCP methylation
K8Z39_22555	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_22565	COG0741	lytic transglycosylase activity
K8Z39_22570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z39_22585	COG0784	Response regulator, receiver
K8Z39_22585	COG0835	chemotaxis
K8Z39_22620	COG1157	protein secretion by the type III secretion system
K8Z39_22630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_22635	COG1766	The M ring may be actively involved in energy transduction
K8Z39_22645	COG1558	bacterial-type flagellum-dependent cell motility
K8Z39_22650	COG1815	bacterial-type flagellum-dependent cell motility
K8Z39_22670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z39_22675	COG1256	bacterial-type flagellum assembly
K8Z39_22695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z39_22710	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z39_22710	COG1776	CheC inhibitor of MCP methylation
K8Z39_22715	COG0643	Histidine kinase
K8Z39_22715	COG2198	Histidine kinase
K8Z39_22720	COG2201	protein-glutamate methylesterase activity
K8Z39_22725	COG1360	Flagellar Motor Protein
K8Z39_22730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z39_22740	COG1923	regulation of RNA biosynthetic process
K8Z39_22780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z39_22785	COG2323	membrane
K8Z39_22795	COG0789	Transcriptional regulator
K8Z39_22795	COG4978	Transcriptional regulator
K8Z39_22800	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z39_22805	COG0475	glutathione-regulated potassium exporter activity
K8Z39_22815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z39_22820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z39_22840	COG1280	lysine exporter protein (LysE YggA)
K8Z39_22845	COG3403	YqcI/YcgG family
K8Z39_22880	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z39_22900	COG0454	-acetyltransferase
K8Z39_22915	COG0438	transferase activity, transferring glycosyl groups
K8Z39_22920	COG1215	transferase activity, transferring glycosyl groups
K8Z39_22935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z39_22945	COG3944	biosynthesis protein
K8Z39_22960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z39_22990	COG0456	acetyltransferase
K8Z39_23000	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z39_23010	COG2311	Membrane
K8Z39_23015	COG2233	PERMEase
K8Z39_23025	COG0024	Methionine aminopeptidase
K8Z39_23035	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z39_23040	COG1199	ATP-dependent helicase activity
K8Z39_23050	COG0116	Belongs to the methyltransferase superfamily
K8Z39_23105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_23105	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z39_23115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z39_23120	COG3935	DnaD domain protein
K8Z39_23140	COG1199	ATP-dependent helicase activity
K8Z39_23140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z39_23175	COG0438	transferase activity, transferring glycosyl groups
K8Z39_23195	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z39_23200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_23210	COG2738	Putative neutral zinc metallopeptidase
K8Z39_23225	COG4347	Protein of unknown function (DUF1405)
K8Z39_23230	COG2010	Cytochrome c
K8Z39_23230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z39_23235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z39_23255	COG0457	Tetratricopeptide repeat
K8Z39_23285	COG0142	geranyltranstransferase activity
K8Z39_23295	COG0142	geranyltranstransferase activity
K8Z39_23310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z39_23380	COG0252	asparaginase activity
K8Z39_23385	COG0492	ferredoxin-NADP+ reductase activity
K8Z39_23405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z39_23415	COG0789	Transcriptional regulator
K8Z39_23420	COG1408	metallophosphoesterase
K8Z39_23430	COG1266	CAAX protease self-immunity
K8Z39_23435	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z39_23445	COG1141	Ferredoxin
K8Z39_23450	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z39_23465	COG2096	Adenosyltransferase
K8Z39_23470	COG5002	protein histidine kinase activity
K8Z39_23475	COG0745	RESPONSE REGULATOR receiver
K8Z39_23480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z39_23485	COG1333	cytochrome c biogenesis protein
K8Z39_23495	COG1187	pseudouridine synthase activity
K8Z39_23500	COG0700	Nucleoside recognition
K8Z39_23505	COG2715	membrane protein required for spore maturation
K8Z39_23510	COG1686	Belongs to the peptidase S11 family
K8Z39_23515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z39_23530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z39_23530	COG0392	lysyltransferase activity
K8Z39_23545	COG5002	protein histidine kinase activity
K8Z39_23550	COG0582	viral genome integration into host DNA
K8Z39_23560	COG1801	Protein of unknown function DUF72
K8Z39_23565	COG3852	Histidine kinase
K8Z39_23580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_23585	COG1392	Phosphate transport regulator
K8Z39_23590	COG0306	phosphate transporter
K8Z39_23595	COG0730	response to heat
K8Z39_23645	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_23655	COG2197	response regulator
K8Z39_23660	COG4585	Histidine kinase
K8Z39_23665	COG4758	membrane
K8Z39_23680	COG1757	Na H antiporter
K8Z39_23705	COG0733	neurotransmitter:sodium symporter activity
K8Z39_23710	COG1648	precorrin-2 dehydrogenase activity
K8Z39_23730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z39_23735	COG0529	Catalyzes the synthesis of activated sulfate
K8Z39_23755	COG0019	diaminopimelate decarboxylase activity
K8Z39_23765	COG1368	sulfuric ester hydrolase activity
K8Z39_23770	COG1183	phosphatidylcholine synthase activity
K8Z39_23785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z39_23860	COG0440	acetolactate synthase activity
K8Z39_23865	COG0028	Belongs to the TPP enzyme family
K8Z39_23870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z39_23890	COG3874	Sporulation protein YtfJ
K8Z39_23895	COG4709	membrane
K8Z39_23900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z39_23905	COG1301	dicarboxylic acid transport
K8Z39_23915	COG1846	Transcriptional regulator
K8Z39_23965	COG0716	FMN binding
K8Z39_23990	COG1696	Membrane protein involved in D-alanine export
K8Z39_24000	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z39_24005	COG2070	2-Nitropropane dioxygenase
K8Z39_24010	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z39_24020	COG1335	isochorismatase
K8Z39_24030	COG1522	sequence-specific DNA binding
K8Z39_24050	COG1131	(ABC) transporter
K8Z39_24060	COG1131	(ABC) transporter
K8Z39_24065	COG1725	Transcriptional regulator
K8Z39_24070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z39_24080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z39_24085	COG1780	Probably involved in ribonucleotide reductase function
K8Z39_24115	COG4873	Protein conserved in bacteria
K8Z39_24130	COG0720	synthase
K8Z39_24140	COG5002	protein histidine kinase activity
K8Z39_24150	COG2318	DinB family
K8Z39_24160	COG1846	Transcriptional regulator
K8Z39_24165	COG3852	Histidine kinase
K8Z39_24175	COG2861	carbohydrate metabolic process
K8Z39_24185	COG0235	Class ii aldolase
K8Z39_24200	COG1349	DNA-binding transcription factor activity
K8Z39_24225	COG3842	ATPase activity
K8Z39_24230	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z39_24245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z39_24255	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z39_24260	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_24280	COG2030	dehydratase
K8Z39_24290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z39_24295	COG0861	Integral membrane protein TerC family
K8Z39_24300	COG2116	formate transmembrane transporter activity
K8Z39_24310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z39_24330	COG2186	Transcriptional regulator
K8Z39_24335	COG5002	protein histidine kinase activity
K8Z39_24340	COG0745	RESPONSE REGULATOR receiver
K8Z39_24350	COG3835	regulator
K8Z39_24355	COG0277	FAD linked oxidase domain protein
K8Z39_24360	COG0247	lactate metabolic process
K8Z39_24365	COG2340	Cysteine-rich secretory protein family
K8Z39_24375	COG0564	pseudouridine synthase activity
K8Z39_24385	COG2409	Drug exporters of the RND superfamily
K8Z39_24400	COG1177	transmembrane transport
K8Z39_24405	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z39_24415	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_24450	COG0681	Belongs to the peptidase S26 family
K8Z39_24455	COG1686	Belongs to the peptidase S11 family
K8Z39_24465	COG2226	methyltransferase
K8Z39_24485	COG1668	transmembrane transport
K8Z39_24490	COG4152	abc transporter atp-binding protein
K8Z39_24535	COG1476	TRANSCRIPTIONal
K8Z39_24545	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z39_24565	COG2226	methyltransferase
K8Z39_24605	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z39_24610	COG1620	l-lactate permease
K8Z39_24645	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z39_24645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z39_24655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z39_24680	COG2382	esterase
K8Z39_24690	COG2153	protein acetylation
K8Z39_24735	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z39_24750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z39_24770	COG0457	Tetratricopeptide repeat
K8Z39_24770	COG0463	Glycosyl transferase, family 2
K8Z39_24790	COG1216	Glycosyl transferase, family 2
K8Z39_24795	COG0772	Belongs to the SEDS family
K8Z39_24810	COG0564	pseudouridine synthase activity
K8Z39_24820	COG2357	RelA SpoT domain protein
K8Z39_24830	COG4116	CYTH
K8Z39_24835	COG2346	COG2346, Truncated hemoglobins
K8Z39_24850	COG1164	Oligoendopeptidase f
K8Z39_24860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z39_24870	COG0861	Integral membrane protein TerC family
K8Z39_24885	COG4166	transmembrane transport
K8Z39_24890	COG0534	Mate efflux family protein
K8Z39_24895	COG4608	Belongs to the ABC transporter superfamily
K8Z39_24900	COG0444	Belongs to the ABC transporter superfamily
K8Z39_24905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z39_24910	COG0601	transmembrane transport
K8Z39_24915	COG4166	transmembrane transport
K8Z39_24925	COG0180	Tryptophanyl-tRNA synthetase
K8Z39_24935	COG5504	Zn-dependent protease
K8Z39_24940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z39_24945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z39_24960	COG2267	carboxylic ester hydrolase activity
K8Z39_24980	COG0561	phosphatase activity
K8Z39_24995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_25020	COG2996	Protein conserved in bacteria
K8Z39_25040	COG0004	ammonium transporteR
K8Z39_25045	COG3339	Conserved Protein
K8Z39_25070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z39_25080	COG0753	catalase activity
K8Z39_25090	COG0367	asparagine synthase
K8Z39_25115	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z39_25175	COG0398	Pfam SNARE associated Golgi protein
K8Z39_25195	COG1278	Cold shock
K8Z39_25210	COG2224	Isocitrate lyase
K8Z39_25215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z39_25225	COG3693	PFAM glycoside hydrolase, family 10
K8Z39_25230	COG0840	transmembrane signaling receptor activity
K8Z39_25235	COG0501	Belongs to the peptidase M48B family
K8Z39_25255	COG0745	RESPONSE REGULATOR receiver
K8Z39_25260	COG2205	protein histidine kinase activity
K8Z39_25270	COG2207	Transcriptional regulator
K8Z39_25270	COG3708	Transcriptional regulator
K8Z39_25275	COG1595	DNA-templated transcription, initiation
K8Z39_25285	COG1078	dGTPase activity
K8Z39_25290	COG1408	metallophosphoesterase
K8Z39_25295	COG1073	alpha beta
K8Z39_25385	COG4208	sulfate ABC transporter
K8Z39_25395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K8Z39_25405	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_25415	COG0095	Lipoate-protein ligase
K8Z39_25420	COG1234	tRNA 3'-trailer cleavage
K8Z39_25430	COG1609	Transcriptional regulator
K8Z39_25435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_25470	COG1309	transcriptional regulator
K8Z39_25485	COG1484	DNA-dependent DNA replication
K8Z39_25520	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z39_25535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z39_25540	COG2329	Antibiotic biosynthesis monooxygenase
K8Z39_25545	COG3428	Bacterial PH domain
K8Z39_25550	COG3402	PFAM membrane-flanked domain
K8Z39_25555	COG0697	spore germination
K8Z39_25590	COG3428	Bacterial PH domain
K8Z39_25595	COG3402	PFAM membrane-flanked domain
K8Z39_25605	COG1309	transcriptional regulator
K8Z39_25620	COG4473	ABC transporter
K8Z39_25625	COG1131	(ABC) transporter
K8Z39_25630	COG0537	adenosine 5'-monophosphoramidase activity
K8Z39_25635	COG4980	gas vesicle protein
K8Z39_25660	COG3973	AAA domain
K8Z39_25665	COG0772	Belongs to the SEDS family
K8Z39_25675	COG1595	DNA-templated transcription, initiation
K8Z39_25690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z39_25700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z39_25705	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z39_25710	COG3620	sequence-specific DNA binding
K8Z39_25715	COG2140	Oxalate decarboxylase
K8Z39_25735	COG2267	carboxylic ester hydrolase activity
K8Z39_25745	COG0457	Tetratricopeptide repeat
K8Z39_25750	COG0346	lactoylglutathione lyase activity
K8Z39_25755	COG0346	lactoylglutathione lyase activity
K8Z39_25770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_25780	COG4717	serine-type aminopeptidase activity
K8Z39_25785	COG0420	3'-5' exonuclease activity
K8Z39_25805	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z39_25815	COG2186	Transcriptional regulator
K8Z39_25820	COG2807	transmembrane transport
K8Z39_25860	COG0784	Response regulator, receiver
K8Z39_25860	COG2205	protein histidine kinase activity
K8Z39_25860	COG5002	protein histidine kinase activity
K8Z39_25865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z39_25870	COG2208	phosphoserine phosphatase activity
K8Z39_25880	COG1191	sigma factor activity
K8Z39_25960	COG2373	Large extracellular alpha-helical protein
K8Z39_25990	COG2376	Dihydroxyacetone kinase
K8Z39_26000	COG2376	Dihydroxyacetone kinase
K8Z39_26025	COG0640	Transcriptional regulator
K8Z39_26030	COG2814	Major facilitator Superfamily
K8Z39_26045	COG1183	phosphatidylcholine synthase activity
K8Z39_26095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z39_26110	COG1522	sequence-specific DNA binding
K8Z39_26115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z39_26130	COG0577	efflux transmembrane transporter activity
K8Z39_26165	COG2801	Transposase and inactivated derivatives
K8Z39_26175	COG1073	alpha beta
K8Z39_26205	COG2020	methyltransferase activity
K8Z39_26255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_26275	COG0477	Major facilitator Superfamily
K8Z39_26290	COG1842	Phage shock protein A
K8Z39_26300	COG1288	antiporter activity
K8Z39_26305	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K8Z39_26330	COG0305	Participates in initiation and elongation during chromosome replication
K8Z39_26350	COG0305	Participates in initiation and elongation during chromosome replication
K8Z39_26365	COG0494	nUDIX hydrolase
K8Z39_26370	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z39_26375	COG4565	transcriptional regulatory protein
K8Z39_26380	COG3290	protein histidine kinase activity
K8Z39_26385	COG0477	Major facilitator Superfamily
K8Z39_26485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_26500	COG0322	excinuclease ABC activity
K8Z39_26505	COG4608	Belongs to the ABC transporter superfamily
K8Z39_26510	COG0444	Belongs to the ABC transporter superfamily
K8Z39_26515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z39_26520	COG0601	transmembrane transport
K8Z39_26560	COG1363	Peptidase, m42
K8Z39_26580	COG1024	Enoyl-CoA hydratase
K8Z39_26600	COG2244	polysaccharide biosynthetic process
K8Z39_26605	COG0659	secondary active sulfate transmembrane transporter activity
K8Z39_26620	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_26625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z39_26630	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_26630	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_26640	COG0561	phosphatase activity
K8Z39_26655	COG3527	Alpha-acetolactate decarboxylase
K8Z39_26660	COG0028	Belongs to the TPP enzyme family
K8Z39_26690	COG0189	ligase activity
K8Z39_26705	COG1126	abc transporter atp-binding protein
K8Z39_26710	COG0765	amino acid transport
K8Z39_26715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_26720	COG1132	(ABC) transporter
K8Z39_26725	COG1132	(ABC) transporter
K8Z39_26730	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_26745	COG0531	amino acid
K8Z39_26755	COG0753	catalase activity
K8Z39_26760	COG0693	protein deglycase activity
K8Z39_26775	COG2211	Major facilitator Superfamily
K8Z39_26780	COG4533	DNA binding
K8Z39_26795	COG1733	regulation of RNA biosynthetic process
K8Z39_26800	COG2814	Major facilitator Superfamily
K8Z39_26805	COG1309	transcriptional regulator
K8Z39_26825	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_26830	COG0165	Argininosuccinate lyase
K8Z39_26830	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K8Z39_26835	COG1522	sequence-specific DNA binding
K8Z39_26855	COG2259	Doxx family
K8Z39_26865	COG1263	PTS System
K8Z39_26865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_26875	COG1737	Transcriptional regulator
K8Z39_26885	COG0475	glutathione-regulated potassium exporter activity
K8Z39_26890	COG0531	amino acid
K8Z39_26925	COG0586	Pfam SNARE associated Golgi protein
K8Z39_26960	COG3546	catalase activity
K8Z39_26965	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_26980	COG5522	Integral membrane protein (intg_mem_TP0381)
K8Z39_26990	COG1136	(ABC) transporter
K8Z39_26995	COG0577	efflux transmembrane transporter activity
K8Z39_27000	COG1388	LysM domain
K8Z39_27000	COG3584	3D domain protein
K8Z39_27025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z39_27030	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z39_27035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z39_27035	COG3711	transcriptional antiterminator
K8Z39_27050	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8Z39_27055	COG0604	alcohol dehydrogenase
K8Z39_27060	COG1316	TRANSCRIPTIONal
K8Z39_27070	COG0730	response to heat
K8Z39_27075	COG2210	Belongs to the sulfur carrier protein TusA family
K8Z39_27090	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z39_27095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_27095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z39_27100	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z39_27100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z39_27105	COG1937	Protein conserved in bacteria
K8Z39_27110	COG0446	pyridine nucleotide-disulphide oxidoreductase
K8Z39_27120	COG3591	Belongs to the peptidase S1B family
K8Z39_27130	COG2719	SpoVR family
K8Z39_27135	COG0778	Nitroreductase
K8Z39_27195	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_27200	COG2252	PERMEase
K8Z39_27210	COG1136	(ABC) transporter
K8Z39_27235	COG1846	Transcriptional regulator
K8Z39_27240	COG2814	Major facilitator Superfamily
K8Z39_27245	COG2205	protein histidine kinase activity
K8Z39_27285	COG0351	phosphomethylpyrimidine kinase
K8Z39_27290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z39_27300	COG2104	thiamine diphosphate biosynthetic process
K8Z39_27305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_27310	COG0352	thiamine-phosphate diphosphorylase activity
K8Z39_27315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z39_27320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_27325	COG1116	anion transmembrane transporter activity
K8Z39_27330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z39_27350	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z39_27470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z39_27475	COG0581	inorganic phosphate transmembrane transporter activity
K8Z39_27480	COG0573	inorganic phosphate transmembrane transporter activity
K8Z39_27485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z39_27490	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z39_27490	COG1918	ferrous iron import across plasma membrane
K8Z39_27495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z39_27500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z39_27515	COG0531	amino acid
K8Z39_27520	COG0697	spore germination
K8Z39_27525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z39_27540	COG4990	cell redox homeostasis
K8Z39_27545	COG0833	amino acid
K8Z39_27555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z39_27560	COG1845	cytochrome c oxidase, subunit III
K8Z39_27570	COG0475	glutathione-regulated potassium exporter activity
K8Z39_27570	COG0569	domain protein
K8Z39_27580	COG2153	protein acetylation
K8Z39_27595	COG2252	PERMEase
K8Z39_27600	COG1113	amino acid transport
K8Z39_27615	COG1114	Component of the transport system for branched-chain amino acids
K8Z39_27620	COG3104	oligopeptide transport
K8Z39_27640	COG1476	TRANSCRIPTIONal
K8Z39_27645	COG3583	domain protein
K8Z39_27645	COG3584	3D domain protein
K8Z39_27650	COG0840	transmembrane signaling receptor activity
K8Z39_27705	COG1063	alcohol dehydrogenase
K8Z39_27735	COG1879	ABC-type sugar transport system periplasmic component
K8Z39_27740	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z39_27755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z39_27760	COG1609	Transcriptional regulator
K8Z39_27765	COG0477	Major facilitator Superfamily
K8Z39_27770	COG1846	Transcriptional regulator
K8Z39_27815	COG5002	protein histidine kinase activity
K8Z39_27820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z39_27825	COG2378	regulation of single-species biofilm formation
K8Z39_27835	COG1595	DNA-templated transcription, initiation
K8Z39_27850	COG0833	amino acid
K8Z39_27855	COG0765	amino acid transport
K8Z39_27860	COG0765	amino acid transport
K8Z39_27865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_27870	COG1126	abc transporter atp-binding protein
K8Z39_27875	COG1115	amino acid carrier protein
K8Z39_27880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z39_27885	COG0697	spore germination
K8Z39_27900	COG0366	Alpha amylase catalytic
K8Z39_27905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_27905	COG1263	PTS System
K8Z39_27910	COG2188	Transcriptional regulator
K8Z39_27915	COG0531	amino acid
K8Z39_27935	COG0714	Associated with various cellular activities
K8Z39_27940	COG4548	von Willebrand factor, type A
K8Z39_27950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_27960	COG2226	methyltransferase
K8Z39_27970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_27975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_27980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_27985	COG3104	oligopeptide transport
K8Z39_28000	COG1620	l-lactate permease
K8Z39_28005	COG1027	Aspartate ammonia-lyase
K8Z39_28010	COG1253	flavin adenine dinucleotide binding
K8Z39_28015	COG0346	lactoylglutathione lyase activity
K8Z39_28020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_28025	COG1316	TRANSCRIPTIONal
K8Z39_28030	COG2720	vancomycin resistance protein
K8Z39_28050	COG3227	Zinc metalloprotease (Elastase)
K8Z39_28065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z39_28070	COG2217	Heavy metal translocating P-type atpase
K8Z39_28075	COG0640	Transcriptional regulator
K8Z39_28100	COG2427	Protein of unknown function (DUF1641)
K8Z39_28105	COG3383	formate dehydrogenase (NAD+) activity
K8Z39_28110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z39_28115	COG0454	-acetyltransferase
K8Z39_28115	COG0456	acetyltransferase
K8Z39_28125	COG0745	RESPONSE REGULATOR receiver
K8Z39_28130	COG5002	protein histidine kinase activity
K8Z39_28140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_28145	COG0697	spore germination
K8Z39_28155	COG0281	malic enzyme
K8Z39_28160	COG3493	citrate carrier protein
K8Z39_28165	COG4565	transcriptional regulatory protein
K8Z39_28170	COG3290	protein histidine kinase activity
K8Z39_28180	COG4990	cell redox homeostasis
K8Z39_28190	COG5002	protein histidine kinase activity
K8Z39_28190	COG3850	Histidine kinase
K8Z39_28195	COG0745	RESPONSE REGULATOR receiver
K8Z39_28200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z39_28210	COG0395	ABC-type sugar transport system, permease component
K8Z39_28215	COG1175	transmembrane transport
K8Z39_28220	COG3842	ATPase activity
K8Z39_28225	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z39_28250	COG2851	Citrate transporter
K8Z39_28255	COG4565	transcriptional regulatory protein
K8Z39_28260	COG3290	protein histidine kinase activity
K8Z39_28270	COG2268	Band 7 protein
K8Z39_28275	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z39_28285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z39_28305	COG2766	serine protein kinase
K8Z39_28310	COG1716	ATPase activity
K8Z39_28310	COG5001	Diguanylate cyclase
K8Z39_28315	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z39_28340	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z39_28405	COG0582	viral genome integration into host DNA
K8Z39_28430	COG4974	Belongs to the 'phage' integrase family
K8Z39_28535	COG0735	belongs to the Fur family
K8Z39_28540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z39_28560	COG4555	ABC transporter
K8Z39_28575	COG0067	glutamate synthase
K8Z39_28575	COG0069	glutamate synthase activity
K8Z39_28575	COG0070	glutamate synthase
K8Z39_28580	COG4129	membrane
K8Z39_28585	COG1132	(ABC) transporter
K8Z39_28610	COG1194	a g-specific adenine glycosylase
K8Z39_28615	COG1988	membrane-bound metal-dependent
K8Z39_28645	COG1090	epimerase
K8Z39_28650	COG1228	amidohydrolase
K8Z39_28670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z39_28690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z39_28690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_28700	COG0463	Glycosyl transferase, family 2
K8Z39_28715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z39_28720	COG1263	PTS System
K8Z39_28720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_28750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z39_28755	COG0833	amino acid
K8Z39_28765	COG3829	transcription factor binding
K8Z39_28780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z39_28785	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z39_28805	COG0535	radical SAM domain protein
K8Z39_28815	COG0387	Pfam Sodium calcium exchanger
K8Z39_28820	COG3871	stress protein (general stress protein 26)
K8Z39_28835	COG0586	Pfam SNARE associated Golgi protein
K8Z39_28855	COG0697	spore germination
K8Z39_28860	COG2217	Heavy metal translocating P-type atpase
K8Z39_28865	COG1295	ribonuclease BN
K8Z39_28875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z39_28890	COG3853	Toxic anion resistance protein (TelA)
K8Z39_28900	COG0861	Integral membrane protein TerC family
K8Z39_28905	COG2310	stress, protein
K8Z39_28910	COG2310	stress, protein
K8Z39_28915	COG2310	stress, protein
K8Z39_28945	COG2270	Major facilitator Superfamily
K8Z39_28995	COG1116	anion transmembrane transporter activity
K8Z39_29005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z39_29025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z39_29055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z39_29055	COG2190	(PTS) system
K8Z39_29055	COG1263	PTS System
K8Z39_29060	COG0366	Alpha amylase catalytic
K8Z39_29075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z39_29080	COG0549	Belongs to the carbamate kinase family
K8Z39_29105	COG0840	transmembrane signaling receptor activity
K8Z39_29115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z39_29120	COG0765	amino acid transport
K8Z39_29130	COG0723	plastoquinol--plastocyanin reductase activity
K8Z39_29130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z39_29135	COG2814	Major facilitator Superfamily
K8Z39_29140	COG3541	Predicted nucleotidyltransferase
K8Z39_29160	COG5002	protein histidine kinase activity
K8Z39_29185	COG0166	Belongs to the GPI family
K8Z39_29195	COG0492	ferredoxin-NADP+ reductase activity
K8Z39_29200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z39_29205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_29210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z39_29230	COG0450	alkyl hydroperoxide reductase
K8Z39_29245	COG1473	amidohydrolase
K8Z39_29275	COG4807	Protein conserved in bacteria
K8Z39_29280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z39_29290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z39_29310	COG2309	aminopeptidase activity
K8Z39_29320	COG2076	Multidrug Resistance protein
K8Z39_29325	COG1012	belongs to the aldehyde dehydrogenase family
K8Z39_29335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z39_29345	COG1597	lipid kinase activity
K8Z39_29365	COG4682	membrane
K8Z39_29370	COG1846	Transcriptional regulator
K8Z39_29375	COG0003	Pfam Anion-transporting ATPase
K8Z39_29390	COG1464	Belongs to the NlpA lipoprotein family
K8Z39_29395	COG2011	ABC-type metal ion transport system permease component
K8Z39_29405	COG1335	isochorismatase
K8Z39_29420	COG4851	CamS sex pheromone cAM373 precursor
K8Z39_29430	COG0210	DNA helicase
K8Z39_29455	COG0151	Belongs to the GarS family
K8Z39_29465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z39_29475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z39_29490	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z39_29500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z39_29505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z39_29510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z39_29540	COG0697	spore germination
K8Z39_29560	COG1216	Glycosyl transferase, family 2
K8Z39_29560	COG0463	Glycosyl transferase, family 2
K8Z39_29570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z39_29610	COG0745	RESPONSE REGULATOR receiver
K8Z39_29615	COG2205	protein histidine kinase activity
K8Z39_29655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z39_29680	COG5002	protein histidine kinase activity
K8Z39_29690	COG2252	PERMEase
K8Z39_29710	COG4824	toxin secretion phage lysis holin
K8Z39_29800	COG3728	DNA packaging
K8Z39_29800	COG5484	DNA packaging
K8Z39_29850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K8Z39_29855	COG1687	branched-chain amino acid
K8Z39_29880	COG2233	PERMEase
K8Z39_29885	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z39_29890	COG0288	reversible hydration of carbon dioxide
K8Z39_29895	COG1522	sequence-specific DNA binding
K8Z39_29925	COG0542	response to heat
K8Z39_29930	COG0494	nUDIX hydrolase
K8Z39_29935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K8Z39_29950	COG0457	Tetratricopeptide repeat
K8Z39_30085	COG3344	reverse transcriptase
K8Z39_30100	COG3344	reverse transcriptase
K8Z39_30285	COG3344	reverse transcriptase
K8Z39_30300	COG2814	Major facilitator Superfamily
K8Z39_30335	COG3344	reverse transcriptase
K8Z39_30355	COG3344	reverse transcriptase
K8Z39_30415	COG2311	Membrane
K8Z39_30475	COG2801	Transposase and inactivated derivatives
K8Z39_30480	COG0457	Tetratricopeptide repeat
K8Z39_30500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z39_30530	COG2002	toxin-antitoxin pair type II binding
K8Z39_30535	COG4166	transmembrane transport
K8Z39_30555	COG4974	Belongs to the 'phage' integrase family
K8Z39_30625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K8Z39_30640	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_30655	COG4824	toxin secretion phage lysis holin
K8Z39_30680	COG5444	nuclease activity
K8Z39_30725	COG4974	Belongs to the 'phage' integrase family
K8Z39_30740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z39_30755	COG1073	alpha beta
K8Z39_30770	COG3104	oligopeptide transport
K8Z39_30800	COG0457	Tetratricopeptide repeat
K8Z39_30820	COG4974	Belongs to the 'phage' integrase family
K8Z39_30900	COG1132	(ABC) transporter
K8Z39_30905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z39_30915	COG1131	(ABC) transporter
K8Z39_30935	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8Z39_30975	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_30975	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_30985	COG3227	Zinc metalloprotease (Elastase)
K8Z39_31000	COG3011	Protein conserved in bacteria
K8Z39_31015	COG0457	Tetratricopeptide repeat
K8Z39_31050	COG1132	(ABC) transporter
K8Z39_31070	COG1475	DNA binding
K8Z39_31125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z39_31130	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_31130	COG3321	synthase
K8Z39_31130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_31130	COG0300	oxidoreductase activity
K8Z39_31130	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_31145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z39_31150	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z39_31165	COG1960	acyl-CoA dehydrogenase activity
K8Z39_31185	COG3321	synthase
K8Z39_31185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_31185	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_31185	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z39_31185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z39_31185	COG3321	synthase
K8Z39_31185	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_31185	COG0300	oxidoreductase activity
K8Z39_31185	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z39_31185	COG0300	oxidoreductase activity
K8Z39_31240	COG0667	Aldo Keto reductase
K8Z39_31265	COG1396	sequence-specific DNA binding
K8Z39_31280	COG1216	Glycosyl transferase, family 2
K8Z39_31285	COG1024	Enoyl-CoA hydratase
K8Z39_31305	COG1484	DNA-dependent DNA replication
K8Z39_31460	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_31480	COG0739	heme binding
K8Z39_31485	COG0741	lytic transglycosylase activity
K8Z39_31515	COG1361	Conserved repeat domain
K8Z39_31520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z39_31545	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_31580	COG0457	Tetratricopeptide repeat
K8Z39_31600	COG3344	reverse transcriptase
K8Z39_31685	COG1136	(ABC) transporter
K8Z39_31940	COG0592	DNA-directed DNA polymerase activity
K8Z39_31945	COG4712	double-strand break repair protein
K8Z39_31980	COG3344	reverse transcriptase
K8Z39_31990	COG3344	reverse transcriptase
K8Z39_32220	COG3344	reverse transcriptase
K8Z39_32265	COG2311	Membrane
K8Z39_32285	COG0457	Tetratricopeptide repeat
K8Z39_32310	COG0583	DNA-binding transcription factor activity
K8Z39_32315	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z39_32360	COG0730	response to heat
K8Z39_32385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z39_32410	COG2002	toxin-antitoxin pair type II binding
K8Z39_32415	COG4166	transmembrane transport
K8Z39_32435	COG4974	Belongs to the 'phage' integrase family
K8Z39_32465	COG0583	DNA-binding transcription factor activity
K8Z39_32470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_32475	COG0402	S-adenosylhomocysteine deaminase activity
K8Z39_32550	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z39_32565	COG4824	toxin secretion phage lysis holin
K8Z39_32605	COG0840	transmembrane signaling receptor activity
K8Z39_32615	COG3300	MHYT domain
K8Z39_32615	COG5001	Diguanylate cyclase
K8Z39_32650	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_32650	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_32655	COG0475	glutathione-regulated potassium exporter activity
K8Z39_32660	COG0490	domain, Protein
K8Z39_32665	COG0840	transmembrane signaling receptor activity
K8Z39_32720	COG0583	DNA-binding transcription factor activity
K8Z39_32730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z39_32765	COG0640	Transcriptional regulator
K8Z39_32810	COG0675	Transposase, IS605 OrfB family
K8Z39_32820	COG2828	Protein conserved in bacteria
K8Z39_32895	COG0791	NLP P60 protein
K8Z39_32895	COG0741	lytic transglycosylase activity
K8Z39_33150	COG0457	Tetratricopeptide repeat
K8Z39_33195	COG0739	heme binding
K8Z39_33370	COG3344	reverse transcriptase
K8Z39_33505	COG3344	reverse transcriptase
K8Z39_33510	COG0741	lytic transglycosylase activity
K8Z39_33510	COG0791	NLP P60 protein
K8Z39_33595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z39_33595	COG0551	DNA topoisomerase type I activity
K8Z39_33645	COG0457	Tetratricopeptide repeat
K8Z39_33650	COG4166	transmembrane transport
K8Z39_33680	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
K8Z39_33720	COG0741	lytic transglycosylase activity
K8Z39_33720	COG0791	NLP P60 protein
K8Z39_33925	COG1923	regulation of RNA biosynthetic process
K8Z39_33935	COG0457	Tetratricopeptide repeat
K8Z39_34170	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_34170	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_34255	COG1073	alpha beta
K8Z39_34265	COG2197	response regulator
K8Z39_34270	COG1476	TRANSCRIPTIONal
K8Z39_34335	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z39_34475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z39_34545	COG3331	DNA recombination
K8Z39_34665	COG1396	sequence-specific DNA binding
K8Z39_34720	COG3409	Peptidoglycan-binding domain 1 protein
K8Z39_34720	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z39_34720	COG1388	LysM domain
K8Z39_34855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z39_35050	COG0457	Tetratricopeptide repeat
K8Z39_35160	COG3344	reverse transcriptase
K8Z39_35165	COG3654	unkown
K8Z39_35175	COG0582	viral genome integration into host DNA
K8Z39_35225	COG0457	Tetratricopeptide repeat
K8Z39_35245	COG0501	Belongs to the peptidase M48B family