locus-tag class description BMB171_C0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BMB171_C0003 ENOG410848D S4 domain protein YaaA BMB171_C0006 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BMB171_C0008 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BMB171_C0014 ENOG4105ZMH deoxynucleoside kinase BMB171_C0016 ENOG4105GTG Isochorismatase BMB171_C0017 ENOG4108Z6B deaminase BMB171_C0018 ENOG4105C6E dna polymerase iii BMB171_C0022 ENOG41067KS pro-sigma K processing BMB171_C0024 ENOG4105CXN decarboxylase BMB171_C0025 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BMB171_C0026 ENOG4105FA2 dna polymerase iii BMB171_C0027 ENOG4105MA4 psp1 domain protein BMB171_C0029 ENOG41060K3 Methyltransferase BMB171_C0030 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BMB171_C0031 ENOG4105KRN Transcriptional regulator, abrb family BMB171_C0032 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BMB171_C0033 ENOG4105F8V Hydrolase, tatD family BMB171_C0034 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BMB171_C0036 ENOG4105XFA sporulation peptidase YabG BMB171_C0037 ENOG4105W42 Veg protein BMB171_C0040 ENOG4105DFT pur operon repressor BMB171_C0041 ENOG4105KME endoribonuclease L-psp BMB171_C0045 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BMB171_C0046 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BMB171_C0048 ENOG4108JA2 transcriptioN-repair coupling factor BMB171_C0049 ENOG4108M14 stage v sporulation protein t BMB171_C0051 ENOG4108IY2 MazG family BMB171_C0052 ENOG41082I2 s4 domain protein BMB171_C0053 ENOG4105VYY sporulation protein yabp BMB171_C0056 ENOG41060GV RNA binding s1 domain protein BMB171_C0058 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BMB171_C0059 ENOG4108UGV hypoxanthine phosphoribosyltransferase BMB171_C0060 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BMB171_C0063 ENOG4105C6T cysteine synthase BMB171_C0064 ENOG4105CRQ synthase (Component I) BMB171_C0065 ENOG4105DDQ anthranilate synthase BMB171_C0066 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BMB171_C0067 ENOG4105EEI dihydropteroate synthase BMB171_C0068 ENOG4105KRF dihydroneopterin aldolase BMB171_C0069 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BMB171_C0073 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BMB171_C0076 ENOG4108Z0C Uvrb UvrC protein BMB171_C0079 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BMB171_C0080 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BMB171_C0081 ENOG4105CTP PilT protein domain protein BMB171_C0082 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BMB171_C0085 ENOG4105D7W serine acetyltransferase BMB171_C0088 ENOG4105C2N RNA methyltransferase TrmH family group 3 BMB171_C0089 ENOG4105M0M Tetracycline resistance protein BMB171_C0090 ENOG4105QIV RNA polymerase BMB171_C0092 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BMB171_C0097 ENOG4107Y49 methyltransferase BMB171_C0101 ENOG4105XPM ribosomal protein BMB171_C0120 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BMB171_C0125 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BMB171_C0127 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BMB171_C0129 ENOG41067V7 50S ribosomal protein L36 BMB171_C0134 ENOG4108JJB ABC transporter BMB171_C0135 ENOG4108JJB ABC transporter BMB171_C0136 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BMB171_C0137 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BMB171_C0142 ENOG4105D1F ATP-binding protein BMB171_C0145 ENOG4108NMV polysaccharide deacetylase BMB171_C0149 ENOG4105C8B TIGR00159 family BMB171_C0150 ENOG4107U5W ybbr family BMB171_C0152 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BMB171_C0158 ENOG4108PSK reductase BMB171_C0159 ENOG4108UMI ABC transporter, permease BMB171_C0160 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BMB171_C0161 ENOG4105D01 (LipO)protein BMB171_C0162 ENOG4105CB2 alcohol dehydrogenase BMB171_C0164 ENOG4105IQ5 FAD linked oxidase domain protein BMB171_C0167 ENOG4105C2C drug resistance transporter, Bcr CflA BMB171_C0171 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BMB171_C0172 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BMB171_C0173 ENOG4105C3U ABC transporter BMB171_C0174 ENOG4108JQ7 (ABC) transporter BMB171_C0178 ENOG4108J59 Extracellular solute-binding protein, family 5 BMB171_C0179 ENOG4108J59 Extracellular solute-binding protein, family 5 BMB171_C0183 ENOG4105E0C molybdate abc transporter BMB171_C0184 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BMB171_C0185 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BMB171_C0186 ENOG4105EGI Transcriptional regulator BMB171_C0190 ENOG4105F6E Acyl-transferase BMB171_C0193 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BMB171_C0197 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BMB171_C0202 ENOG4105C5H ABC transporter BMB171_C0203 ENOG4105DEF Extracellular solute-binding protein, family 5 BMB171_C0205 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BMB171_C0206 ENOG4105C3U ABC transporter BMB171_C0207 ENOG4108JQ7 (ABC) transporter BMB171_C0208 ENOG410667J hydrolase BMB171_C0214 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BMB171_C0215 ENOG4105ERH Fumarylacetoacetate hydrolase BMB171_C0217 ENOG4105CUB amino acid BMB171_C0218 ENOG4108SC4 )-transporter BMB171_C0219 ENOG4105CPF Cell wall formation (By similarity) BMB171_C0220 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BMB171_C0225 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BMB171_C0226 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BMB171_C0228 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BMB171_C0231 ENOG4105K8N protein family UPF0079, ATPase BMB171_C0232 ENOG41072GX Peptidase M22 Glycoprotease BMB171_C0233 ENOG410801F ribosomal-protein-alanine acetyltransferase BMB171_C0234 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BMB171_C0235 ENOG4105C5H ABC transporter BMB171_C0238 ENOG4108TYN CAAX amino terminal protease family protein BMB171_C0244 ENOG4105C7N Xanthine uracil vitamin C permease BMB171_C0247 ENOG4105BZU Histidine kinase BMB171_C0249 ENOG4107ZXU DSBA oxidoreductase BMB171_C0255 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BMB171_C0258 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BMB171_C0260 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) BMB171_C0262 ENOG4108SHN Glycosyl transferase, family 2 BMB171_C0263 ENOG4105SX7 Transporter BMB171_C0266 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BMB171_C0267 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BMB171_C0268 ENOG4105C83 adenylosuccinate lyase BMB171_C0270 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BMB171_C0275 ENOG4108V3E phosphoribosylglycinamide formyltransferase BMB171_C0276 ENOG4105DC1 bifunctional purine biosynthesis protein purh BMB171_C0277 ENOG4105C12 Phosphoribosylglycinamide synthetase BMB171_C0282 ENOG4105C4R Atp-dependent dna helicase BMB171_C0283 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BMB171_C0287 ENOG4108W2Y isochorismatase BMB171_C0288 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BMB171_C0289 ENOG4108UMI ABC transporter, permease BMB171_C0290 ENOG4105D01 (LipO)protein BMB171_C0293 ENOG410834F Transcriptional regulator BMB171_C0294 ENOG4107I77 yiaA/B two helix domain BMB171_C0296 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BMB171_C0298 ENOG4105CBD Diacylglycerol kinase BMB171_C0300 ENOG4108JPW Aminotransferase BMB171_C0302 ENOG4105C26 Dehydrogenase BMB171_C0303 ENOG4105KPY Small multidrug resistance protein BMB171_C0309 ENOG4105D9N nucleoside BMB171_C0310 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BMB171_C0312 ENOG4108W15 Protein of unknown function (DUF1456) BMB171_C0315 ENOG4105DTQ mandelate racemase muconate lactonizing BMB171_C0317 ENOG4105DFD Na H antiporter BMB171_C0321 ENOG4105D3R alkyl hydroperoxide reductase BMB171_C0322 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BMB171_C0323 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BMB171_C0324 ENOG4107W7X Aldolase BMB171_C0325 ENOG4105EHG Permease protein BMB171_C0326 ENOG4105DQ5 transport system permease protein BMB171_C0327 ENOG4108V5C ABC transporter BMB171_C0328 ENOG4105CAY ferredoxin--nadp reductase BMB171_C0330 ENOG4106UIA BMB171_C0333 ENOG4105BZU Histidine kinase BMB171_C0337 ENOG410756H nucleotidyltransferase BMB171_C0338 ENOG4105DQ6 Transposase BMB171_C0340 ENOG4105D2S major facilitator superfamily BMB171_C0343 ENOG4105E5Q amino acid AbC transporter BMB171_C0344 ENOG4105EAB amino acid AbC transporter BMB171_C0345 ENOG4105CDA abc transporter atp-binding protein BMB171_C0346 ENOG4105C8Q Methyl-accepting chemotaxis BMB171_C0349 ENOG4105DBV ornithine carbamoyltransferase BMB171_C0351 ENOG4105C5B carbamate kinase BMB171_C0352 ENOG4108W63 CRP FNR family transcriptional regulator BMB171_C0354 ENOG4105DNP FAD linked oxidase domain protein BMB171_C0356 ENOG4105CI1 PTS System BMB171_C0359 ENOG4105C9U ATP-dependent DNA helicase RecQ BMB171_C0360 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BMB171_C0361 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BMB171_C0362 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BMB171_C0366 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BMB171_C0367 ENOG4105D2X ABC transporter substrate-binding protein BMB171_C0369 ENOG4105C5H ABC transporter BMB171_C0375 ENOG41062JF Transcriptional regulator BMB171_C0378 ENOG4105DEU major facilitator superfamily BMB171_C0381 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BMB171_C0386 ENOG4108N0M stress protein BMB171_C0387 ENOG4106FN3 tellurium resistance protein BMB171_C0388 ENOG4106FN3 tellurium resistance protein BMB171_C0389 ENOG4107TS3 membrane protein, TerC BMB171_C0390 ENOG4108TTB tellurium resistance protein BMB171_C0393 ENOG41068PA UPF0435 protein BMB171_C0394 ENOG4105KJF protein tyrosine phosphatase BMB171_C0396 ENOG4107U9T Pfam:Ribonuclease_BN BMB171_C0397 ENOG4105C59 p-type ATPase BMB171_C0398 ENOG4108IPJ Membrane BMB171_C0400 ENOG4105C3F Signal peptidase i BMB171_C0402 ENOG4107ZTW SNARE associated Golgi BMB171_C0405 ENOG410606W general stress protein BMB171_C0406 ENOG4105UPD Calcium Proton BMB171_C0413 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BMB171_C0414 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BMB171_C0416 ENOG4108JUB Transcriptional regulator BMB171_C0418 ENOG4108IQI permease BMB171_C0427 ENOG4108A04 Beta-lactamase BMB171_C0430 ENOG4105CKK Glycosyl transferase, family 2 BMB171_C0431 ENOG4107QQG Dehydrogenase BMB171_C0432 ENOG4105C3I Nad-dependent epimerase dehydratase BMB171_C0435 ENOG4105F1A Pyruvate formate-lyase BMB171_C0436 ENOG4108QBV Monogalactosyldiacylglycerol synthase BMB171_C0439 ENOG4105CI2 imidazolone-5-propionate hydrolase BMB171_C0440 ENOG4105ECP epimerase BMB171_C0444 ENOG41067AE Membrane-bound metal-dependent hydrolase BMB171_C0445 ENOG4105CEN a g-specific adenine glycosylase BMB171_C0446 ENOG4106BXE BMB171_C0450 ENOG4105BZ1 (ABC) transporter BMB171_C0451 ENOG4107NBY Membrane BMB171_C0452 ENOG4105CBC glutamate synthase BMB171_C0454 ENOG4108IUW ABC transporter BMB171_C0458 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BMB171_C0459 ENOG4105G5W regulator Fur family BMB171_C0462 ENOG4105CDY transcriptional regulatory protein BMB171_C0464 ENOG4108JQC penicillin-binding protein 1A BMB171_C0465 ENOG4108R9S DSBA oxidoreductase BMB171_C0466 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BMB171_C0468 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BMB171_C0469 ENOG4105BZU Histidine kinase BMB171_C0470 ENOG4105CYN Serine protein kinase BMB171_C0471 ENOG4106AKX UPF0229 protein BMB171_C0474 ENOG4105C94 Transporter BMB171_C0477 ENOG4105DZ6 Band 7 protein BMB171_C0479 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BMB171_C0480 ENOG4108V9W transcriptional regulatory protein BMB171_C0481 ENOG4105D4T Citrate transporter BMB171_C0486 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BMB171_C0487 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BMB171_C0488 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BMB171_C0489 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BMB171_C0490 ENOG4105BZ7 extracellular solute-binding protein family 1 BMB171_C0491 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BMB171_C0492 ENOG4108STX response regulator BMB171_C0493 ENOG4105US7 Histidine kinase BMB171_C0499 ENOG4108MRH transcriptional regulatory protein BMB171_C0501 ENOG4105C6K Malic enzyme BMB171_C0504 ENOG4108UZ3 Transporter BMB171_C0505 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BMB171_C0507 ENOG4105BZU Histidine kinase BMB171_C0510 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BMB171_C0511 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BMB171_C0513 ENOG4108JB9 formate dehydrogenase BMB171_C0518 ENOG4105CUB amino acid BMB171_C0520 ENOG4105C59 p-type ATPase BMB171_C0521 ENOG4105DAP Nicotinate phosphoribosyltransferase BMB171_C0528 ENOG41073R8 VanW family BMB171_C0529 ENOG4108KGH TRANSCRIPTIONal BMB171_C0530 ENOG4105D9N nucleoside BMB171_C0531 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BMB171_C0532 ENOG4105C37 (CBS) domain BMB171_C0533 ENOG4108IJ0 Aspartate ammonia-lyase BMB171_C0534 ENOG4105DAA L-lactate BMB171_C0537 ENOG4105DUX Transporter BMB171_C0538 ENOG4108MES Periplasmic binding protein BMB171_C0539 ENOG4105DQ5 transport system permease protein BMB171_C0540 ENOG4108IHU transport system permease protein BMB171_C0541 ENOG4105E0A ABC, transporter BMB171_C0543 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BMB171_C0544 ENOG4105EXW epimerase dehydratase BMB171_C0546 ENOG4107T89 von Willebrand factor, type A BMB171_C0547 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BMB171_C0548 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BMB171_C0550 ENOG4105BZU Histidine kinase BMB171_C0551 ENOG4105D5Q Arginine ornithine antiporter BMB171_C0552 ENOG4107414 GntR family transcriptional regulator BMB171_C0553 ENOG4105C5Y PTS System BMB171_C0554 ENOG4105CG3 alpha amylase, catalytic region BMB171_C0557 ENOG4105E1K spore germination protein BMB171_C0559 ENOG4105CRN Aminoglycoside phosphotransferase BMB171_C0560 ENOG4105BZG amino acid carrier protein BMB171_C0561 ENOG4105CDA abc transporter atp-binding protein BMB171_C0562 ENOG4105CT1 (ABC) transporter BMB171_C0563 ENOG4105EAD ABC transporter BMB171_C0564 ENOG4105DRP amino acid AbC transporter BMB171_C0565 ENOG4108IQI permease BMB171_C0568 ENOG4105D29 Helix-turn-helix type 11 domain protein BMB171_C0569 ENOG4105NAE bifunctional deaminase-reductase domain protein BMB171_C0570 ENOG4105BZU Histidine kinase BMB171_C0573 ENOG4105CHH sulfate transporter BMB171_C0574 ENOG41068KF Universal stress protein BMB171_C0575 ENOG4105CXY transporter BMB171_C0576 ENOG41067TZ transcriptional regulator, MarR family BMB171_C0577 ENOG4105C0R drug resistance transporter emrb qaca subfamily BMB171_C0578 ENOG4105ETE Transcriptional regulator (LacI family BMB171_C0579 ENOG4108RVA ribokinase BMB171_C0581 ENOG4105C2J ABC transporter BMB171_C0582 ENOG4105CNN ABC, transporter BMB171_C0583 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BMB171_C0584 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BMB171_C0590 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) BMB171_C0595 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BMB171_C0596 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BMB171_C0597 ENOG41069ER domain protein BMB171_C0598 ENOG4105VZ8 Transcriptional regulator BMB171_C0599 ENOG4107D63 BMB171_C0602 ENOG4105DUX Transporter BMB171_C0606 ENOG4105C85 amino acid BMB171_C0607 ENOG4105C7N Xanthine uracil vitamin C permease BMB171_C0610 ENOG4105MA6 gCN5-related N-acetyltransferase BMB171_C0614 ENOG4105BZ9 Cytochrome C oxidase, subunit I BMB171_C0615 ENOG4105E2S oxidase) subunit II BMB171_C0620 ENOG4105E1V na solute symporter BMB171_C0623 ENOG4108NHD germination protein BMB171_C0624 ENOG4105CE1 Ferrous iron transport protein b BMB171_C0625 ENOG4105CE1 Ferrous iron transport protein b BMB171_C0626 ENOG4105CE1 Ferrous iron transport protein b BMB171_C0627 ENOG4105CVA phosphate BMB171_C0628 ENOG4105C8U phosphate abc transporter BMB171_C0629 ENOG4105E2Z phosphate ABC transporter (Permease BMB171_C0631 ENOG41080XQ Signal transduction protein with cbs domains BMB171_C0635 ENOG4105ETU transcriptional activator (TenA BMB171_C0637 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BMB171_C0639 ENOG4108VEU Thiamine monophosphate synthase BMB171_C0640 ENOG41080HI glycine oxidase BMB171_C0643 ENOG4105D06 uba thif-type nad fad binding protein BMB171_C0644 ENOG4105DWF phosphomethylpyrimidine kinase BMB171_C0650 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) BMB171_C0653 ENOG4108INS Transcriptional regulator BMB171_C0655 ENOG4105C7N Xanthine uracil vitamin C permease BMB171_C0657 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BMB171_C0661 ENOG4105C5Y PTS System BMB171_C0664 ENOG4105K63 Thioredoxin BMB171_C0668 ENOG4108B31 Spore germination protein BMB171_C0672 ENOG4107Y03 Nitroreductase BMB171_C0673 ENOG4105ED1 spovr family BMB171_C0677 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BMB171_C0678 ENOG4105XTG Pfam:DUF156 BMB171_C0679 ENOG4105VFE sira family BMB171_C0680 ENOG4107TPS domain protein BMB171_C0681 ENOG4105VFE sira family BMB171_C0683 ENOG4105VFE sira family BMB171_C0684 ENOG41085GJ domain protein BMB171_C0685 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BMB171_C0686 ENOG41087NI Sulfite exporter TauE/SafE BMB171_C0688 ENOG4108KGH TRANSCRIPTIONal BMB171_C0693 ENOG4105EMD TRANSCRIPTIONal BMB171_C0694 ENOG4105VCP PTS System BMB171_C0695 ENOG4105VZJ PTS System BMB171_C0698 ENOG41069ER domain protein BMB171_C0699 ENOG4107RBB ABC transporter, permease BMB171_C0700 ENOG4105C19 ABC transporter BMB171_C0706 ENOG4105WEF catalase BMB171_C0711 ENOG4107T5V SNARE associated Golgi BMB171_C0717 ENOG4105CUB amino acid BMB171_C0718 ENOG4107RWR Sodium hydrogen exchanger BMB171_C0720 ENOG4106KNT transcriptional regulator BMB171_C0721 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BMB171_C0728 ENOG4108YXU transcriptional regulator AsnC family BMB171_C0730 ENOG4105KPY Small multidrug resistance protein BMB171_C0736 ENOG4105NF4 modulator of drug activity BMB171_C0737 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BMB171_C0738 ENOG4105E5W Transporter BMB171_C0740 ENOG4107RKG DJ-1/PfpI family BMB171_C0741 ENOG4105CH6 catalase BMB171_C0743 ENOG4105D5Q Arginine ornithine antiporter BMB171_C0744 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BMB171_C0746 ENOG4105C26 Dehydrogenase BMB171_C0747 ENOG4105BZ1 (ABC) transporter BMB171_C0748 ENOG4105BZ1 (ABC) transporter BMB171_C0751 ENOG4105DRP amino acid AbC transporter BMB171_C0752 ENOG4105CDA abc transporter atp-binding protein BMB171_C0755 ENOG410839P BMB171_C0757 ENOG4108UH6 UPF0754 membrane protein BMB171_C0759 ENOG4105BZU Histidine kinase BMB171_C0760 ENOG4105WH1 Two component transcriptional regulator luxr family BMB171_C0762 ENOG4107FQX Alpha-acetolactate decarboxylase BMB171_C0763 ENOG4108VX5 3-methyladenine DNA glycosylase BMB171_C0766 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BMB171_C0767 ENOG4105D4P Coproporphyrinogen iii oxidase BMB171_C0768 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_C0770 ENOG4105CHH sulfate transporter BMB171_C0775 ENOG4105CGU Enoyl-CoA hydratase BMB171_C0779 ENOG4105DER m42 family BMB171_C0784 ENOG4105CTU Proline racemase BMB171_C0785 ENOG4105CIF Ornithine Cyclodeaminase BMB171_C0789 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BMB171_C0791 ENOG4108JQ7 (ABC) transporter BMB171_C0803 ENOG4108IBT Inherit from COG: transposase BMB171_C0817 ENOG4105CSH Transporter BMB171_C0819 ENOG4108MRH transcriptional regulatory protein BMB171_C0822 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BMB171_C0831 ENOG4105CDU Replicative dna helicase BMB171_C0843 ENOG4105C0R drug resistance transporter emrb qaca subfamily BMB171_C0846 ENOG4105D9U N-acetyltransferase BMB171_C0848 ENOG4105F6J Alpha beta hydrolase fold BMB171_C0856 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BMB171_C0859 ENOG4105CMT Dihydroxyacetone kinase BMB171_C0861 ENOG4105CMT Dihydroxyacetone kinase BMB171_C0870 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BMB171_C0877 ENOG4105WN5 stage II sporulation protein BMB171_C0879 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_C0881 ENOG4108MJI response regulator BMB171_C0882 ENOG4105BZU Histidine kinase BMB171_C0883 ENOG4105BZU Histidine kinase BMB171_C0887 ENOG4105K8R UPF0145 protein BMB171_C0890 ENOG4107QHE Choloylglycine hydrolase BMB171_C0893 ENOG4107VRP DNA repair exonuclease BMB171_C0894 ENOG4106D4I domain protein BMB171_C0900 ENOG4108MUZ hydrolase BMB171_C0905 ENOG4105F0F Oxalate decarboxylase BMB171_C0908 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BMB171_C0911 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BMB171_C0919 ENOG4105EEM helicase BMB171_C0921 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BMB171_C0925 ENOG4105K59 histidine triad (HIT) protein BMB171_C0932 ENOG410905X membrane-flanked domain protein BMB171_C0933 ENOG4105CKV Membrane BMB171_C0938 ENOG410905X membrane-flanked domain protein BMB171_C0939 ENOG4105CKV Membrane BMB171_C0940 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BMB171_C0941 ENOG4105BZ4 penicillin-binding protein BMB171_C0943 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BMB171_C0944 ENOG4105C1Q protoporphyrinogen oxidase BMB171_C0949 ENOG4105NA0 Transcriptional regulator BMB171_C0952 ENOG4105ECB domain protein BMB171_C0955 ENOG4108MK9 spermidine N(1)-acetyltransferase BMB171_C0957 ENOG4106AXD BMB171_C0958 ENOG4108RQ5 Beta-lactamase domain-containing protein BMB171_C0959 ENOG4105DF9 Lipoate-protein, ligase BMB171_C0962 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_C0964 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BMB171_C0965 ENOG4108I5D sulfate abc transporter BMB171_C0966 ENOG4105ECW sulfate abc transporter BMB171_C0967 ENOG4108IJ6 ABC transporter BMB171_C0978 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BMB171_C0979 ENOG4107RN3 metallophosphoesterase BMB171_C0980 ENOG4107TVP HD domain protein BMB171_C0982 ENOG41086D8 Transcriptional regulator BMB171_C0985 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BMB171_C0988 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BMB171_C0989 ENOG4105C8Q Methyl-accepting chemotaxis BMB171_C0990 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) BMB171_C0993 ENOG4107QP3 malate synthase g BMB171_C0997 ENOG4105VEQ Cold shock protein BMB171_C1004 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BMB171_C1005 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BMB171_C1010 ENOG4105ERH Fumarylacetoacetate hydrolase BMB171_C1011 ENOG4105C8Y Acetylornithine aminotransferase BMB171_C1012 ENOG4106BKT UPF0344 protein BMB171_C1014 ENOG4105CAQ asparagine synthetase BMB171_C1015 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BMB171_C1016 ENOG4105CH6 catalase BMB171_C1017 ENOG4105BZU Histidine kinase BMB171_C1020 ENOG4108VPT UPF0234 protein BMB171_C1021 ENOG4105QNR S1 RNA binding domain protein BMB171_C1022 ENOG4105CNA YD repeat protein BMB171_C1024 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BMB171_C1025 ENOG4107AYK membrAne BMB171_C1026 ENOG41073B9 BMB171_C1027 ENOG4108KP7 hydrolase BMB171_C1029 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BMB171_C1034 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BMB171_C1035 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BMB171_C1038 ENOG4105C31 Tryptophanyl-tRNA synthetase BMB171_C1040 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BMB171_C1041 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BMB171_C1043 ENOG4108JQ7 (ABC) transporter BMB171_C1044 ENOG4105UQX Mate efflux family protein BMB171_C1048 ENOG4108ZCF integral membrane protein BMB171_C1050 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BMB171_C1052 ENOG4105DPN Oligoendopeptidase f BMB171_C1054 ENOG4108Z18 K06886 hemoglobin BMB171_C1055 ENOG4105MIX Adenylate cyclase BMB171_C1056 ENOG4106EFP UPF0738 protein BMB171_C1058 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BMB171_C1059 ENOG4105EMS pseudouridine synthase BMB171_C1064 ENOG4105K64 Glycosyl transferase, family 2 BMB171_C1068 ENOG4107TVC Glycosyl transferase, family 2 BMB171_C1072 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BMB171_C1073 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BMB171_C1075 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BMB171_C1084 ENOG4108ZMI UPF0477 protein BMB171_C1090 ENOG4105CK7 Sodium proline symporter BMB171_C1092 ENOG4105CRQ synthase (Component I) BMB171_C1093 ENOG4105DDQ anthranilate synthase BMB171_C1094 ENOG4108I0Q anthranilate phosphoribosyltransferase BMB171_C1095 ENOG4105DK0 Indole-3-glycerol phosphate synthase BMB171_C1096 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase BMB171_C1097 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BMB171_C1098 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) BMB171_C1109 ENOG4105C7S Dehydrogenase BMB171_C1110 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BMB171_C1111 ENOG4105VZ8 Transcriptional regulator BMB171_C1116 ENOG4108IUX (ABC) transporter BMB171_C1117 ENOG4105RHA ABC transporter, permease BMB171_C1121 ENOG4105DZ1 carboxypeptidase BMB171_C1129 ENOG4105C26 Dehydrogenase BMB171_C1130 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BMB171_C1131 ENOG4105F38 ABC transporter, permease BMB171_C1132 ENOG4105D38 putrescine abc transporter BMB171_C1133 ENOG4107RUE extracellular solute-binding protein family 1 BMB171_C1135 ENOG4105EYF MMPL domain protein BMB171_C1137 ENOG4108YBP pseudouridine synthase BMB171_C1139 ENOG4105K4I Scp-like extracellular BMB171_C1140 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BMB171_C1141 ENOG4105CQB FAD linked oxidase domain protein BMB171_C1144 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C1145 ENOG4105BZU Histidine kinase BMB171_C1146 ENOG4105JXH GntR family transcriptional regulator BMB171_C1150 ENOG4106A3R peptidase BMB171_C1152 ENOG4108QTI )-transporter BMB171_C1153 ENOG4107TS3 membrane protein, TerC BMB171_C1154 ENOG4105CZN Potassium uptake protein BMB171_C1155 ENOG410681C small acid-soluble spore protein BMB171_C1156 ENOG4108Z7G MaoC domain protein dehydratase BMB171_C1160 ENOG4105CHR reductase BMB171_C1166 ENOG4105C4Y ABC transporter BMB171_C1167 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BMB171_C1168 ENOG4107RCV ABC transporter, permease BMB171_C1172 ENOG4105E98 transcriptional regulator DeoR family BMB171_C1175 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BMB171_C1177 ENOG4105PXI polysaccharide deacetylase BMB171_C1179 ENOG4105BZU Histidine kinase BMB171_C1180 ENOG41090MY MarR family Transcriptional regulator BMB171_C1182 ENOG4106DF1 BMB171_C1184 ENOG4105BZU Histidine kinase BMB171_C1185 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BMB171_C1186 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BMB171_C1187 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BMB171_C1195 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BMB171_C1196 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BMB171_C1197 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BMB171_C1198 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BMB171_C1199 ENOG4105CZV ABC transporter BMB171_C1201 ENOG4105CJ1 ABC, transporter BMB171_C1209 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BMB171_C1210 ENOG4105EA8 2-Nitropropane dioxygenase BMB171_C1211 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BMB171_C1213 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BMB171_C1217 ENOG4105NQC Flavodoxin BMB171_C1225 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BMB171_C1229 ENOG4105CZN Potassium uptake protein BMB171_C1230 ENOG41063Y9 BMB171_C1231 ENOG4105KBJ sporulation protein ytfj BMB171_C1234 ENOG4105CM2 brancheD-chain amino acid aminotransferase BMB171_C1235 ENOG4105C7K acetolactate synthase BMB171_C1236 ENOG4108ZP8 Acetolactate synthase small subunit BMB171_C1237 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BMB171_C1240 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BMB171_C1243 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BMB171_C1244 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BMB171_C1245 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BMB171_C1247 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BMB171_C1248 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BMB171_C1250 ENOG4105KPZ phosphoribosyl-atp pyrophosphatase BMB171_C1251 ENOG4107RVV histidinol phosphate phosphatase, hisj family BMB171_C1253 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BMB171_C1254 ENOG4105E0M Sulfatase BMB171_C1256 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BMB171_C1259 ENOG4107S4M Sulfate adenylate transferase BMB171_C1260 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BMB171_C1261 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BMB171_C1263 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BMB171_C1264 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BMB171_C1265 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BMB171_C1266 ENOG4105C8J )-transporter BMB171_C1270 ENOG4105DFD Na H antiporter BMB171_C1274 ENOG4105ENE Histidine kinase BMB171_C1275 ENOG4105WH1 Two component transcriptional regulator luxr family BMB171_C1278 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BMB171_C1282 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BMB171_C1286 ENOG4105CJ3 phosphate transporter BMB171_C1287 ENOG4107GRR phosphate transport regulator BMB171_C1288 ENOG4105BZ4 penicillin-binding protein BMB171_C1292 ENOG4105BZU Histidine kinase BMB171_C1293 ENOG4105I3N Conserved Protein BMB171_C1296 ENOG4105BZU Histidine kinase BMB171_C1297 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BMB171_C1302 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BMB171_C1303 ENOG4105DZ1 carboxypeptidase BMB171_C1304 ENOG4108JIC nucleoside recognition domain protein BMB171_C1306 ENOG4105FE9 pseudouridine synthase BMB171_C1307 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BMB171_C1308 ENOG4107TWT Cytochrome c biogenesis protein BMB171_C1309 ENOG4105CRE cytochrome C BMB171_C1310 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C1311 ENOG4105BZU Histidine kinase BMB171_C1312 ENOG4108WBT adenosyltransferase BMB171_C1315 ENOG4108SAX Membrane BMB171_C1318 ENOG4105C9U ATP-dependent DNA helicase RecQ BMB171_C1319 ENOG4105I7S Abortive infection protein BMB171_C1321 ENOG4107RGJ metallophosphoesterase BMB171_C1322 ENOG4108XDN Transcriptional regulator BMB171_C1323 ENOG4108S6Z Negative regulator of genetic competence BMB171_C1328 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BMB171_C1329 ENOG4107RB3 L-asparaginase BMB171_C1332 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BMB171_C1335 ENOG4105S2F BMB171_C1336 ENOG41065D1 BMB171_C1342 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BMB171_C1345 ENOG4105XXQ heptaprenyl diphosphate synthase component I BMB171_C1347 ENOG4105EAH synthase BMB171_C1348 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BMB171_C1349 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BMB171_C1350 ENOG4105D49 3-dehydroquinate synthase BMB171_C1352 ENOG41068YB TPR repeat-containing protein BMB171_C1355 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BMB171_C1356 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BMB171_C1363 ENOG4108JYZ YitT family BMB171_C1364 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BMB171_C1365 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BMB171_C1367 ENOG4105FJR Lmbe family BMB171_C1368 ENOG4105CPK Glycosyl transferase (Group 1 BMB171_C1371 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BMB171_C1374 ENOG4105DVT helicase BMB171_C1375 ENOG4105YAC BMB171_C1379 ENOG4105CSM endonuclease III BMB171_C1382 ENOG4105BZ4 penicillin-binding protein BMB171_C1390 ENOG4106F55 Protein of unknown function (DUF1273) BMB171_C1392 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BMB171_C1399 ENOG4105DVT helicase BMB171_C1400 ENOG4105CTD carboxy-peptidase BMB171_C1401 ENOG4105DQ6 Transposase BMB171_C1404 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BMB171_C1406 ENOG4105C2W permease BMB171_C1407 ENOG4105DHF Membrane BMB171_C1408 ENOG410890F Dynamin family BMB171_C1410 ENOG4108W0I acetyltransferase BMB171_C1412 ENOG4105KHC sulfurtransferase BMB171_C1419 ENOG4105HTX biosynthesis protein BMB171_C1425 ENOG4105CPK Glycosyl transferase (Group 1 BMB171_C1439 ENOG4108SZE gCN5-related N-acetyltransferase BMB171_C1443 ENOG41081VK Ribonuclease BMB171_C1455 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BMB171_C1457 ENOG4107RWR Sodium hydrogen exchanger BMB171_C1458 ENOG4105CN5 Metallo-Beta-Lactamase BMB171_C1459 ENOG4108Z5V transcriptional regulator, merr family BMB171_C1461 ENOG4105H67 Protein of unknown function (DUF421) BMB171_C1462 ENOG41080C8 DUF218 domain BMB171_C1471 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BMB171_C1473 ENOG4107R0U MotA TolQ exbB proton channel BMB171_C1474 ENOG4105ER2 Ompa motb domain protein BMB171_C1475 ENOG4107YTP response regulator receiver protein BMB171_C1476 ENOG4105CBS Chea signal transduction histidine kinase BMB171_C1477 ENOG4105DD5 Flagellar motor switch protein BMB171_C1480 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BMB171_C1484 ENOG4105EFC phage portal protein HK97 family BMB171_C1498 ENOG4105BZU Histidine kinase BMB171_C1502 ENOG4105E1Q flagellar hook-associated protein BMB171_C1503 ENOG4105DTJ flagellar hook-associated protein BMB171_C1504 ENOG4107TPX flagellar hook-associated BMB171_C1507 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BMB171_C1508 ENOG4108ZC9 flagellar basal-body rod protein flgc BMB171_C1509 ENOG41075Z6 flagellar hook-basal body complex protein fliE BMB171_C1510 ENOG4107U2N Flagellar M-ring protein BMB171_C1511 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BMB171_C1517 ENOG4105BZE flagellar hook protein, FlgE BMB171_C1520 ENOG4107R88 Chemotaxis protein (CheV) BMB171_C1522 ENOG4105I03 Flagellin BMB171_C1523 ENOG4105I03 Flagellin BMB171_C1524 ENOG4105I03 Flagellin BMB171_C1525 ENOG4105I03 Flagellin BMB171_C1526 ENOG4105E4C Lytic transglycosylase catalytic BMB171_C1528 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BMB171_C1529 ENOG4105DD5 Flagellar motor switch protein BMB171_C1531 ENOG4105CN7 Flagellar biosynthetic protein FliP BMB171_C1532 ENOG4105VS8 Flagellar biosynthetic protein fliq BMB171_C1534 ENOG4105D00 flagellar biosynthetic protein flhB BMB171_C1535 ENOG4105D7B Flagellar biosynthesis protein flha BMB171_C1536 ENOG4105FZW flagellar biosynthesis regulator FlhF BMB171_C1537 ENOG4105KTQ flagellar basal-body rod protein BMB171_C1538 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BMB171_C1543 ENOG4105KAC Antibiotic biosynthesis monooxygenase BMB171_C1548 ENOG4105DUM transcriptional regulator, lysR family BMB171_C1551 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BMB171_C1558 ENOG4105CVJ phosphoglycerate mutase BMB171_C1560 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BMB171_C1564 ENOG4105CAQ asparagine synthetase BMB171_C1568 ENOG4105PGM cation diffusion facilitator family transporter BMB171_C1570 ENOG4105DRR Transcriptional regulator, GntR family BMB171_C1571 ENOG4108UZ3 Transporter BMB171_C1573 ENOG4105CKI cobalamin synthesis protein BMB171_C1574 ENOG4108PJD permease BMB171_C1578 ENOG4105DFD Na H antiporter BMB171_C1580 ENOG4105C9Q fumarate hydratase class II BMB171_C1582 ENOG4107QJQ Mate efflux family protein BMB171_C1583 ENOG4105EC3 peptidase S51, dipeptidase E BMB171_C1587 ENOG4107QIV Cytochrome c biogenesis protein BMB171_C1588 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BMB171_C1591 ENOG4107JM4 Tetratricopeptide repeat BMB171_C1593 ENOG4105BZC d-serine deaminase BMB171_C1594 ENOG4106BRA Membrane BMB171_C1600 ENOG4105CJ1 ABC, transporter BMB171_C1604 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BMB171_C1607 ENOG4108IJ0 Aspartate ammonia-lyase BMB171_C1608 ENOG4105C6K Malic enzyme BMB171_C1618 ENOG4105FVX BMB171_C1619 ENOG4105E09 nadh pyrophosphatase BMB171_C1622 ENOG4105CSR polyphosphate kinase 2 BMB171_C1623 ENOG4105U3E Transcriptional regulator BMB171_C1625 ENOG4105DXI Major Facilitator superfamily BMB171_C1628 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BMB171_C1629 ENOG4105EU0 Major facilitator Superfamily BMB171_C1630 ENOG4105C6T cysteine synthase BMB171_C1634 ENOG4105C8J )-transporter BMB171_C1636 ENOG4105X5K response regulator receiver protein BMB171_C1637 ENOG4105H67 Protein of unknown function (DUF421) BMB171_C1640 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BMB171_C1641 ENOG4105CHR reductase BMB171_C1642 ENOG4105CM2 brancheD-chain amino acid aminotransferase BMB171_C1643 ENOG4105C7K acetolactate synthase BMB171_C1645 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BMB171_C1646 ENOG4105C01 Dihydroxy-acid dehydratase BMB171_C1647 ENOG4105C7B Threonine dehydratase BMB171_C1650 ENOG4105C6X Major Facilitator BMB171_C1651 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BMB171_C1653 ENOG4105DY9 regulatoR BMB171_C1654 ENOG4105CYC Transferase BMB171_C1657 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BMB171_C1662 ENOG41068WN BMB171_C1666 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BMB171_C1667 ENOG4105C72 UPF0176 protein BMB171_C1669 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BMB171_C1671 ENOG4105C0X amino acid BMB171_C1676 ENOG4105K8R UPF0145 protein BMB171_C1679 ENOG4107RHR regulatoR BMB171_C1682 ENOG4105D9N nucleoside BMB171_C1683 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BMB171_C1692 ENOG4107RAQ aminopeptidase BMB171_C1694 ENOG4107R16 Multicopper oxidase BMB171_C1702 ENOG4108T5E Copper resistance protein BMB171_C1703 ENOG4105KTB nuclear export factor GLE1 BMB171_C1704 ENOG4107RT3 EamA-like transporter family BMB171_C1705 ENOG4105GZI Transcriptional regulator BMB171_C1706 ENOG4108Z40 Transcriptional regulator BMB171_C1707 ENOG4107ZXU DSBA oxidoreductase BMB171_C1708 ENOG4108TVJ Nitroreductase BMB171_C1710 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BMB171_C1711 ENOG4106F5Q Membrane BMB171_C1712 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BMB171_C1714 ENOG4105CKI cobalamin synthesis protein BMB171_C1716 ENOG4105C0Z ABC transporter BMB171_C1717 ENOG4108IV0 ABC, transporter BMB171_C1718 ENOG4105C32 Amino acid ABC transporter (Permease) BMB171_C1720 ENOG4105SKE transcriptional Regulator LysR family BMB171_C1726 ENOG4105C4M (Ubiquinol oxidase) subunit I BMB171_C1727 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BMB171_C1728 ENOG4108JJ9 ABC, transporter BMB171_C1729 ENOG4108JJ8 (ABC) transporter BMB171_C1731 ENOG4105K64 Glycosyl transferase, family 2 BMB171_C1733 ENOG4108UT6 Transferase hexapeptide repeat containing protein BMB171_C1741 ENOG4105BZ1 (ABC) transporter BMB171_C1742 ENOG4105EFI regulatoR BMB171_C1743 ENOG4105BZU Histidine kinase BMB171_C1746 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BMB171_C1747 ENOG4108ZJ4 polysaccharide deacetylase BMB171_C1752 ENOG4105D6E homoserine dehydrogenase BMB171_C1757 ENOG4108KGH TRANSCRIPTIONal BMB171_C1759 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BMB171_C1760 ENOG4105BZU Histidine kinase BMB171_C1761 ENOG4107VMI polysaccharide deacetylase BMB171_C1763 ENOG4105KT7 mgtC SapB transporter BMB171_C1764 ENOG4105VRR gCN5-related N-acetyltransferase BMB171_C1766 ENOG4105DUU IucA IucC family protein BMB171_C1767 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_C1770 ENOG4108WBH protein TIM barrel BMB171_C1771 ENOG4105YWU small acid-soluble spore protein BMB171_C1773 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BMB171_C1774 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BMB171_C1782 ENOG4105KRN Transcriptional regulator, abrb family BMB171_C1784 ENOG4105YVS arsR family transcriptional regulator BMB171_C1785 ENOG4105CPC Aldo Keto reductase BMB171_C1786 ENOG4107XZQ multidrug resistance protein BMB171_C1792 ENOG4105C8Q Methyl-accepting chemotaxis BMB171_C1794 ENOG4108K88 Membrane BMB171_C1795 ENOG4108WPJ Ferritin-like domain BMB171_C1798 ENOG4105DEN Luciferase family BMB171_C1800 ENOG4105VMI -acetyltransferase BMB171_C1801 ENOG4107QM2 Aldo Keto reductase BMB171_C1802 ENOG4105CKI cobalamin synthesis protein BMB171_C1804 ENOG4105DSE periplasmic solute binding protein BMB171_C1806 ENOG4105K4T epimerase BMB171_C1808 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BMB171_C1817 ENOG4107T5V SNARE associated Golgi BMB171_C1820 ENOG4108PJD permease BMB171_C1822 ENOG4108S4H thioesterase Superfamily protein BMB171_C1823 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BMB171_C1828 ENOG4105SXS Protein of unknown function (DUF456) BMB171_C1829 ENOG4105C37 (CBS) domain BMB171_C1833 ENOG4108Z7R Chaperone CsaA BMB171_C1837 ENOG4108ZRV stage ii sporulation protein p BMB171_C1839 ENOG4108VXD carboxy-peptidase BMB171_C1841 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BMB171_C1845 ENOG4108ZRV stage ii sporulation protein p BMB171_C1847 ENOG4108X4Q Hydrolase BMB171_C1850 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BMB171_C1853 ENOG41087PP glycosyltransferase MGT family BMB171_C1854 ENOG4108JYZ YitT family BMB171_C1855 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BMB171_C1861 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BMB171_C1867 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) BMB171_C1868 ENOG4108MGT Required for secretion of EsxA and EsxB BMB171_C1882 ENOG4105KBJ sporulation protein ytfj BMB171_C1887 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BMB171_C1891 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BMB171_C1892 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BMB171_C1895 ENOG4105EMN RNA polymerase sigma factor BMB171_C1897 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BMB171_C1898 ENOG4105CNW domain protein BMB171_C1899 ENOG4108V06 Glutathione peroxidase BMB171_C1902 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BMB171_C1905 ENOG4108IUE nitrate reductase beta subunit BMB171_C1906 ENOG4105R3A Nitrate reductase BMB171_C1908 ENOG4107V6Q Cyclic nucleotide-binding domain BMB171_C1909 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BMB171_C1910 ENOG4105D06 uba thif-type nad fad binding protein BMB171_C1911 ENOG4105CVM Molybdenum cofactor synthesis domain protein BMB171_C1912 ENOG4108ZAF Molybdopterin BMB171_C1917 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BMB171_C1918 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BMB171_C1919 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BMB171_C1920 ENOG4108IFG nitrite reductase, (NAD(P)H) BMB171_C1921 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BMB171_C1928 ENOG4105MCT stage V sporulation protein S BMB171_C1937 ENOG4105C5H ABC transporter BMB171_C1943 ENOG4107YX5 Pfam:DUF548 BMB171_C1944 ENOG4105C75 arginyL-tRNA synthetase BMB171_C1947 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BMB171_C1950 ENOG4105C5S asparaginyl-tRNA synthetase BMB171_C1951 ENOG4105C8J )-transporter BMB171_C1955 ENOG4107XGZ Hydrolase BMB171_C1956 ENOG4105CY2 Citrate transporter BMB171_C1960 ENOG4105KD7 acetyltransferase BMB171_C1961 ENOG4105VMP Transcriptional regulator BMB171_C1962 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BMB171_C1967 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BMB171_C1970 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BMB171_C1971 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BMB171_C1973 ENOG4107RVG penicillin-binding protein BMB171_C1974 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BMB171_C1975 ENOG4105E9Q Acyl-transferase BMB171_C1976 ENOG4108UT2 hemolysin iii BMB171_C1978 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BMB171_C1979 ENOG4108RCR degv family BMB171_C1981 ENOG4108KF3 Electron transport protein SCO1 SenC BMB171_C1982 ENOG4107Y70 Heat shock protein BMB171_C1983 ENOG4105CAQ asparagine synthetase BMB171_C1985 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BMB171_C1986 ENOG4108MES Periplasmic binding protein BMB171_C1987 ENOG4105F0I Aminotransferase BMB171_C1992 ENOG4105D8X mechanosensitive ion channel BMB171_C1993 ENOG4105BZU Histidine kinase BMB171_C1994 ENOG4105WH1 Two component transcriptional regulator luxr family BMB171_C1995 ENOG4106KNT transcriptional regulator BMB171_C1996 ENOG4107ZY0 Phenazine biosynthesis-like protein BMB171_C2000 ENOG4105CMG Carbohydrate kinase BMB171_C2001 ENOG4105C6Z Gluconate BMB171_C2003 ENOG4108YV3 Protein of unknown function (DUF2711) BMB171_C2009 ENOG4108IJ8 ABC transporter BMB171_C2011 ENOG4108HQR Glycine betaine BMB171_C2018 ENOG4105C37 (CBS) domain BMB171_C2023 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BMB171_C2026 ENOG4107S4Y M20 DapE family protein YgeY BMB171_C2027 ENOG4108TSC N-acetyltransferase BMB171_C2028 ENOG4108JUB Transcriptional regulator BMB171_C2029 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BMB171_C2037 ENOG410841Q phosphoesterase PA-phosphatase related protein BMB171_C2039 ENOG4105SZ6 Thioredoxin BMB171_C2045 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BMB171_C2053 ENOG4105BZ4 penicillin-binding protein BMB171_C2054 ENOG4105CZM Major Facilitator BMB171_C2055 ENOG4105W8X HesB YadR YfhF-family protein BMB171_C2057 ENOG4105DXD 2-methylcitrate dehydratase BMB171_C2058 ENOG4105CR4 methylisocitrate lyase BMB171_C2059 ENOG4105C1G acyl-Coa dehydrogenase BMB171_C2060 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BMB171_C2062 ENOG4105N14 lysine exporter protein LysE YggA BMB171_C2063 ENOG4105E39 Enoyl-CoA hydratase BMB171_C2066 ENOG4107RFY SbcCD D subunit BMB171_C2067 ENOG4105EYH Exonuclease BMB171_C2072 ENOG4105FCD Major Facilitator BMB171_C2073 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BMB171_C2074 ENOG4105E4F Isochorismate synthase BMB171_C2075 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BMB171_C2076 ENOG4105WQI isochorismatase BMB171_C2077 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_C2078 ENOG4105WQT MbtH domain protein BMB171_C2079 ENOG4105C0R drug resistance transporter emrb qaca subfamily BMB171_C2082 ENOG4105K70 DNA-binding protein BMB171_C2086 ENOG4105BZG amino acid carrier protein BMB171_C2092 ENOG4105FE9 pseudouridine synthase BMB171_C2093 ENOG4105C22 threonyL-tRNA synthetase BMB171_C2094 ENOG4105C19 ABC transporter BMB171_C2100 ENOG41081I9 integral membrane protein BMB171_C2102 ENOG4108Y4K DNA-binding transcriptional activator BMB171_C2104 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BMB171_C2106 ENOG4105EYF MMPL domain protein BMB171_C2111 ENOG4105WCN acetyltransferase BMB171_C2116 ENOG4105C1Q protoporphyrinogen oxidase BMB171_C2118 ENOG41068WN BMB171_C2124 ENOG4107V2S Transcriptional regulator BMB171_C2125 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BMB171_C2129 ENOG4105DND Transcriptional regulator BMB171_C2130 ENOG4108RPX mosc domain containing protein BMB171_C2133 ENOG4105BZ1 (ABC) transporter BMB171_C2134 ENOG4105BZ1 (ABC) transporter BMB171_C2139 ENOG4108JCI Transcriptional regulator BMB171_C2145 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BMB171_C2146 ENOG4108KPJ rna polymerase sigma factor BMB171_C2152 ENOG4105F32 YngK protein BMB171_C2156 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) BMB171_C2157 ENOG4105RD7 BadF BadG BcrA BcrD BMB171_C2158 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BMB171_C2159 ENOG4107STF Involved in phosphonate degradation (By similarity) BMB171_C2160 ENOG4105C7B Threonine dehydratase BMB171_C2165 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BMB171_C2166 ENOG4105C1J atp-dependent rna helicase BMB171_C2168 ENOG4108RZE Tetr family transcriptional regulator BMB171_C2185 ENOG41088CC tellurite resistance protein tehB BMB171_C2187 ENOG4108I0C methyltransferase BMB171_C2188 ENOG4107RA9 decarboxylase BMB171_C2189 ENOG4105K56 Transcriptional regulator BMB171_C2190 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BMB171_C2195 ENOG4105CIN aminoacyl-histidine dipeptidase BMB171_C2201 ENOG4105EJ9 Membrane BMB171_C2202 ENOG4105EQK -acetyltransferase BMB171_C2221 ENOG4108IG5 Transcriptional regulator BMB171_C2226 ENOG4105ED2 Beta-lactamase BMB171_C2228 ENOG4105FQP Beta-lactamase BMB171_C2229 ENOG4107RVG penicillin-binding protein BMB171_C2232 ENOG4107RF6 penicillin-binding protein BMB171_C2233 ENOG4107RF6 penicillin-binding protein BMB171_C2235 ENOG4105DIN metallophosphoesterase BMB171_C2237 ENOG4105CJ1 ABC, transporter BMB171_C2239 ENOG4107Z3H Transcriptional regulator, TetR family BMB171_C2242 ENOG4105C1G acyl-Coa dehydrogenase BMB171_C2243 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BMB171_C2244 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BMB171_C2245 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BMB171_C2246 ENOG4105E39 Enoyl-CoA hydratase BMB171_C2247 ENOG4107QX3 carboxylase BMB171_C2248 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BMB171_C2253 ENOG4105DBI uridine monophosphokinase BMB171_C2256 ENOG4105DZ1 carboxypeptidase BMB171_C2259 ENOG4105T9C HD domain BMB171_C2267 ENOG41075H3 AraC family transcriptional regulator BMB171_C2273 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BMB171_C2277 ENOG4107Y80 Major Facilitator superfamily BMB171_C2278 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BMB171_C2279 ENOG4105KVH Transcriptional regulator BMB171_C2283 ENOG4107V2S Transcriptional regulator BMB171_C2288 ENOG4105EFA 4-hydroxyphenylacetate BMB171_C2290 ENOG4105CPQ Dehydrogenase BMB171_C2292 ENOG410900G Protein of unknown function (DUF421) BMB171_C2293 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BMB171_C2296 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BMB171_C2297 ENOG4105DK7 lysyl-tRNA synthetase BMB171_C2299 ENOG4108VQT Alpha beta hydrolase fold protein BMB171_C2310 ENOG4105D6E homoserine dehydrogenase BMB171_C2312 ENOG4105CPF Cell wall formation (By similarity) BMB171_C2313 ENOG4105ETU transcriptional activator (TenA BMB171_C2316 ENOG4105VTR Integrase BMB171_C2333 ENOG4108QY0 Membrane BMB171_C2352 ENOG4105XSJ toxin secretion phage lysis holin BMB171_C2353 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BMB171_C2357 ENOG4107TSN permease BMB171_C2372 ENOG410667J hydrolase BMB171_C2373 ENOG4105BZU Histidine kinase BMB171_C2374 ENOG4107RF6 penicillin-binding protein BMB171_C2379 ENOG4108JJB ABC transporter BMB171_C2381 ENOG4108HGU Histidine kinase BMB171_C2384 ENOG4105CB2 alcohol dehydrogenase BMB171_C2385 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BMB171_C2386 ENOG4105CJN penicillin-binding protein BMB171_C2395 ENOG4108V4B ThiJ pfpI BMB171_C2397 ENOG4107Y80 Major Facilitator superfamily BMB171_C2400 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BMB171_C2405 ENOG4107Y9U Membrane BMB171_C2413 ENOG4105FCD Major Facilitator BMB171_C2415 ENOG4105E09 nadh pyrophosphatase BMB171_C2416 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BMB171_C2420 ENOG4108XI2 Domain of unknown function (DUF1963) BMB171_C2423 ENOG4108NRW Phospholipase, patatin family BMB171_C2424 ENOG4105KWG Pfam:DUF1696 BMB171_C2426 ENOG4108YYS metal-dependent hydrolase (By similarity) BMB171_C2431 ENOG4105PKS Excinuclease abc c subunit domain protein BMB171_C2438 ENOG4107VFR oxidoreductase BMB171_C2445 ENOG4105U0R haloacid dehalogenase-like hydrolase BMB171_C2448 ENOG4108IUM Glycogen debranching enzyme BMB171_C2450 ENOG4105CGH 5'-nucleotidase BMB171_C2453 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BMB171_C2454 ENOG4105FDR Membrane BMB171_C2455 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BMB171_C2463 ENOG4105MSI germination protein ypeb BMB171_C2469 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BMB171_C2470 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BMB171_C2471 ENOG4107Z3H Transcriptional regulator, TetR family BMB171_C2474 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BMB171_C2477 ENOG4105E98 transcriptional regulator DeoR family BMB171_C2480 ENOG41062ES Transcriptional regulator BMB171_C2484 ENOG4107QKR Dehydrogenase BMB171_C2486 ENOG4107RUY (E1 component), alpha subunit BMB171_C2489 ENOG4105E1F short-chain dehydrogenase reductase BMB171_C2494 ENOG4107SQ8 Glycine betaine BMB171_C2495 ENOG4108IJ7 Glycine betaine BMB171_C2497 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BMB171_C2500 ENOG4105E66 phosphoriboisomerase A BMB171_C2501 ENOG41082BV acetyltransferase BMB171_C2502 ENOG4108M1A Chitin-binding protein BMB171_C2509 ENOG4105MSB protein, conserved in bacteria BMB171_C2513 ENOG4108Z7F N-acetyltransferase BMB171_C2517 ENOG4105EEM helicase BMB171_C2520 ENOG4105C9U ATP-dependent DNA helicase RecQ BMB171_C2529 ENOG4108M1A Chitin-binding protein BMB171_C2533 ENOG4105BZG amino acid carrier protein BMB171_C2534 ENOG4105C26 Dehydrogenase BMB171_C2535 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BMB171_C2536 ENOG4105CTU Proline racemase BMB171_C2537 ENOG4105CTU Proline racemase BMB171_C2538 ENOG41080HI glycine oxidase BMB171_C2540 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BMB171_C2547 ENOG4105DCI Phosphohydrolase BMB171_C2548 ENOG4107T5V SNARE associated Golgi BMB171_C2550 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BMB171_C2554 ENOG4105DTQ mandelate racemase muconate lactonizing BMB171_C2558 ENOG4107SET aldo keto reductase BMB171_C2565 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BMB171_C2566 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BMB171_C2567 ENOG4105BZU Histidine kinase BMB171_C2568 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C2572 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BMB171_C2575 ENOG4105DPN Oligoendopeptidase f BMB171_C2576 ENOG4105EPR degv family BMB171_C2587 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BMB171_C2588 ENOG4106K7D Major facilitator family transporter BMB171_C2592 ENOG4107BMA Transglycosylase associated protein BMB171_C2595 ENOG41089UC methyltransferase, type 11 BMB171_C2602 ENOG4105CHM Aminotransferase BMB171_C2607 ENOG4105DVE abc transporter atp-binding protein BMB171_C2614 ENOG4105C02 permease BMB171_C2616 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BMB171_C2617 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BMB171_C2618 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BMB171_C2619 ENOG4105D7T ABC transporter BMB171_C2626 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BMB171_C2633 ENOG4107VC0 DNA alkylation repair enzyme BMB171_C2634 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BMB171_C2636 ENOG4107VMI polysaccharide deacetylase BMB171_C2638 ENOG4108ZCF integral membrane protein BMB171_C2639 ENOG4105E0M Sulfatase BMB171_C2640 ENOG4105C5H ABC transporter BMB171_C2642 ENOG4105EYF MMPL domain protein BMB171_C2643 ENOG41082JN Transcriptional regulator BMB171_C2647 ENOG4105CIH Imidazole acetol-phosphate transaminase BMB171_C2648 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BMB171_C2649 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BMB171_C2657 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BMB171_C2660 ENOG4105MKU Transcriptional regulator BMB171_C2664 ENOG4105F5R ABC transporter BMB171_C2665 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BMB171_C2667 ENOG4105DKT Transcriptional regulator BMB171_C2668 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BMB171_C2670 ENOG41061GT Aldolase BMB171_C2672 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BMB171_C2679 ENOG4105II7 pyrroline-5-carboxylate reductase BMB171_C2681 ENOG4107258 Transcriptional regulator BMB171_C2684 ENOG4105ECK Fatty Acid Desaturase BMB171_C2686 ENOG4107RBI VanW family BMB171_C2687 ENOG4105G6Z alkaline phosphatase BMB171_C2688 ENOG4105VMP Transcriptional regulator BMB171_C2691 ENOG41068WN BMB171_C2695 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BMB171_C2699 ENOG4105CKK Glycosyl transferase, family 2 BMB171_C2703 ENOG4105C8Y Acetylornithine aminotransferase BMB171_C2712 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BMB171_C2729 ENOG4107EV6 Inherit from COG: YD repeat protein BMB171_C2733 ENOG4108TVJ Nitroreductase BMB171_C2734 ENOG4105FS7 Transcriptional regulator BMB171_C2737 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BMB171_C2740 ENOG4105CMR udp-glucose 4-epimerase BMB171_C2741 ENOG4105C19 ABC transporter BMB171_C2745 ENOG4108DMH HTH_ARAC BMB171_C2746 ENOG4108XET gCN5-related N-acetyltransferase BMB171_C2752 ENOG4107XJU UPF0178 protein BMB171_C2760 ENOG410635A Membrane BMB171_C2762 ENOG4108IQI permease BMB171_C2764 ENOG4105F1N DNA alkylation repair BMB171_C2771 ENOG4107RF6 penicillin-binding protein BMB171_C2777 ENOG4105E7W lamb ycsf family protein BMB171_C2779 ENOG4105P4J Allophanate hydrolase, subunit 1 BMB171_C2782 ENOG4106N3A copper homeostasis protein cutc BMB171_C2783 ENOG4108ZHR arsR family transcriptional regulator BMB171_C2785 ENOG4105FDT acyl-CoA dehydrogenase BMB171_C2788 ENOG4105DWD nucleoside recognition domain protein BMB171_C2797 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BMB171_C2803 ENOG4105E2A Dehydrogenase BMB171_C2805 ENOG4108IJ0 Aspartate ammonia-lyase BMB171_C2806 ENOG4105HDK L-asparaginase BMB171_C2809 ENOG4108B31 Spore germination protein BMB171_C2811 ENOG4105BZU Histidine kinase BMB171_C2816 ENOG41075H3 AraC family transcriptional regulator BMB171_C2818 ENOG4105YWU small acid-soluble spore protein BMB171_C2819 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BMB171_C2820 ENOG4105CUB amino acid BMB171_C2821 ENOG4105II7 pyrroline-5-carboxylate reductase BMB171_C2822 ENOG4108NHD germination protein BMB171_C2823 ENOG4108Q8B Spore germination protein BMB171_C2836 ENOG4105CGH 5'-nucleotidase BMB171_C2838 ENOG4105CHJ isochorismatase hydrolase BMB171_C2847 ENOG4105F6J Alpha beta hydrolase fold BMB171_C2850 ENOG4105CVP deoxyribo-dipyrimidine photolyase BMB171_C2855 ENOG4108TWJ NADH dehydrogenase subunit 5 BMB171_C2856 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BMB171_C2857 ENOG4107VMI polysaccharide deacetylase BMB171_C2858 ENOG4105KY5 gCN5-related N-acetyltransferase BMB171_C2859 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BMB171_C2864 ENOG4105Z7P Acetyltransferase (GNAT) family BMB171_C2866 ENOG4105D6J arsenicaL-resistance protein BMB171_C2867 ENOG41085FC arsR family transcriptional regulator BMB171_C2869 ENOG4105NAE bifunctional deaminase-reductase domain protein BMB171_C2870 ENOG4107P5I polyketide synthase BMB171_C2871 ENOG4108IG5 Transcriptional regulator BMB171_C2872 ENOG4105CHR reductase BMB171_C2877 ENOG4105D7V transposase BMB171_C2898 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BMB171_C2899 ENOG4105C0R drug resistance transporter emrb qaca subfamily BMB171_C2902 ENOG4105K6H D-cysteine desulfhydrase BMB171_C2905 ENOG4105JQZ Methyltransferase BMB171_C2908 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BMB171_C2912 ENOG4105BZU Histidine kinase BMB171_C2914 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BMB171_C2919 ENOG4108JQ1 Dehydrogenase BMB171_C2920 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BMB171_C2924 ENOG410874W AraC family transcriptional regulator BMB171_C2929 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BMB171_C2970 ENOG4108VXD carboxy-peptidase BMB171_C2971 ENOG4105PNM synthesis protein BMB171_C2973 ENOG4108ISG Major Facilitator BMB171_C2976 ENOG4107MII Sugar-specific transcriptional regulator TrmB BMB171_C2977 ENOG4105CZM Major Facilitator BMB171_C2980 ENOG4105DA5 (ABC) transporter BMB171_C2983 ENOG4105CRW Short chain fatty acid transporter BMB171_C2985 ENOG4105DYS nad(p)h dehydrogenase (quinone) BMB171_C2997 ENOG4108K8S endonuclease I BMB171_C3002 ENOG4108Z66 YbaK ebsC protein BMB171_C3003 ENOG4105CUT histidyl-tRNA synthetase BMB171_C3006 ENOG4105KVH Transcriptional regulator BMB171_C3007 ENOG4108RCM Nitroreductase BMB171_C3013 ENOG4108PSK reductase BMB171_C3027 ENOG4105C31 Tryptophanyl-tRNA synthetase BMB171_C3028 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BMB171_C3045 ENOG4105C37 (CBS) domain BMB171_C3047 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BMB171_C3048 ENOG4105FAW cDP-glucose 4,6-dehydratase BMB171_C3055 ENOG4105DDN Pentapeptide repeat-containing protein BMB171_C3056 ENOG4105XDF Protein of unknown function (DUF1272) BMB171_C3058 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BMB171_C3059 ENOG4105CMG Carbohydrate kinase BMB171_C3060 ENOG4105C6Z Gluconate BMB171_C3063 ENOG4105CV1 Transketolase (EC 2.2.1.1) BMB171_C3064 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BMB171_C3065 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BMB171_C3066 ENOG4105CIS alcohol dehydrogenase BMB171_C3067 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BMB171_C3069 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BMB171_C3072 ENOG4105C8Q Methyl-accepting chemotaxis BMB171_C3074 ENOG4108UX3 '-nucleotidase BMB171_C3075 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BMB171_C3076 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BMB171_C3077 ENOG4105KVH Transcriptional regulator BMB171_C3080 ENOG4105CV8 reductase BMB171_C3081 ENOG4105F27 Major Facilitator BMB171_C3083 ENOG41090KN UPF0303 protein BMB171_C3086 ENOG4105C44 Serine transporter BMB171_C3090 ENOG4105KVH Transcriptional regulator BMB171_C3091 ENOG4108TZY GntR Family Transcriptional Regulator BMB171_C3092 ENOG4105D9R oxidoreductase BMB171_C3093 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BMB171_C3094 ENOG4105KVH Transcriptional regulator BMB171_C3102 ENOG4105JAB phenazine biosynthesis protein, phzf family BMB171_C3104 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BMB171_C3105 ENOG4105KVH Transcriptional regulator BMB171_C3108 ENOG4105DQ6 Transposase BMB171_C3109 ENOG4108ZJ4 polysaccharide deacetylase BMB171_C3121 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BMB171_C3123 ENOG4107YXZ hydrolase, family 25 BMB171_C3129 ENOG4105H3G oxidoreductase BMB171_C3140 ENOG4108TN2 lmbE family BMB171_C3142 ENOG4107R3E Citrate transporter BMB171_C3145 ENOG4108MES Periplasmic binding protein BMB171_C3146 ENOG4105EHG Permease protein BMB171_C3147 ENOG4105DQ5 transport system permease protein BMB171_C3148 ENOG4105NX3 Membrane BMB171_C3152 ENOG4107CUJ Protein of unknown function (DUF2690) BMB171_C3154 ENOG4107V2S Transcriptional regulator BMB171_C3158 ENOG4105C98 muts2 protein BMB171_C3160 ENOG4105E5K Alpha-amylase BMB171_C3161 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BMB171_C3162 ENOG4105DPN Oligoendopeptidase f BMB171_C3163 ENOG4108A04 Beta-lactamase BMB171_C3168 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BMB171_C3170 ENOG41082BM Transcriptional regulator, arsr family BMB171_C3171 ENOG4105CIS alcohol dehydrogenase BMB171_C3172 ENOG4105CNG UPF0061 protein BMB171_C3177 ENOG4105CQB FAD linked oxidase domain protein BMB171_C3181 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BMB171_C3184 ENOG4107TPS domain protein BMB171_C3185 ENOG4105CEP NADH dehydrogenase BMB171_C3187 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BMB171_C3189 ENOG4108IAJ Nad-dependent epimerase dehydratase BMB171_C3190 ENOG4105FAW cDP-glucose 4,6-dehydratase BMB171_C3200 ENOG4105BZU Histidine kinase BMB171_C3201 ENOG4105C5H ABC transporter BMB171_C3202 ENOG4107DUR UPF0457 protein BMB171_C3205 ENOG4105BZU Histidine kinase BMB171_C3207 ENOG4105KT7 mgtC SapB transporter BMB171_C3209 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BMB171_C3210 ENOG41073R8 VanW family BMB171_C3212 ENOG4108R1P BMB171_C3214 ENOG4105VEQ Cold shock protein BMB171_C3218 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BMB171_C3222 ENOG410904N short-chain dehydrogenase reductase BMB171_C3224 ENOG4106IQC argininosuccinate lyase BMB171_C3227 ENOG4108IA2 Sodium pantothenate symporter BMB171_C3229 ENOG4105C26 Dehydrogenase BMB171_C3230 ENOG4105CHR reductase BMB171_C3232 ENOG4105EWU Squalene--hopene cyclase BMB171_C3235 ENOG4105FR1 rard protein BMB171_C3236 ENOG410696E Membrane BMB171_C3238 ENOG4105D1F ATP-binding protein BMB171_C3240 ENOG4108ZAF Molybdopterin BMB171_C3241 ENOG4105CVM Molybdenum cofactor synthesis domain protein BMB171_C3242 ENOG4105D06 uba thif-type nad fad binding protein BMB171_C3243 ENOG4105TMB Formate nitrite transporter BMB171_C3245 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BMB171_C3246 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BMB171_C3248 ENOG4108JB9 formate dehydrogenase BMB171_C3249 ENOG4105E1K spore germination protein BMB171_C3252 ENOG4105CUB amino acid BMB171_C3262 ENOG4107QJT sodium dicarboxylate symporter BMB171_C3264 ENOG4108KGH TRANSCRIPTIONal BMB171_C3266 ENOG4105EMN RNA polymerase sigma factor BMB171_C3268 ENOG4105CIG ABC transporter BMB171_C3270 ENOG4105D9R oxidoreductase BMB171_C3272 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BMB171_C3274 ENOG4105K4P CoA-binding domain protein BMB171_C3275 ENOG4105C0H protease BMB171_C3276 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C3278 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BMB171_C3279 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BMB171_C3280 ENOG4105W8X HesB YadR YfhF-family protein BMB171_C3282 ENOG4105D7V transposase BMB171_C3287 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BMB171_C3288 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BMB171_C3289 ENOG4108JJA ABC, transporter BMB171_C3290 ENOG4108I0Z Aconitate hydratase BMB171_C3296 ENOG4105E5W Transporter BMB171_C3297 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BMB171_C3301 ENOG4107F3J Amp-dependent synthetase and ligase BMB171_C3302 ENOG4107ZYJ bioY protein BMB171_C3303 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_C3304 ENOG4108IMY Transcriptional regulator BMB171_C3310 ENOG4107AYK membrAne BMB171_C3312 ENOG4105BZU Histidine kinase BMB171_C3313 ENOG4105FBA Phospholipase Carboxylesterase BMB171_C3314 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BMB171_C3315 ENOG4105CK7 Sodium proline symporter BMB171_C3316 ENOG4105CBC glutamate synthase BMB171_C3317 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BMB171_C3318 ENOG4108VJ1 Transcriptional regulator (CarD family BMB171_C3319 ENOG4108903 Formimidoylglutamase BMB171_C3331 ENOG4107QIV Cytochrome c biogenesis protein BMB171_C3334 ENOG4105CH2 amidohydrolase BMB171_C3336 ENOG4105CJ1 ABC, transporter BMB171_C3339 ENOG4107RSM transcriptional regulator BMB171_C3340 ENOG41067MG lrgb family BMB171_C3348 ENOG4105BZ1 (ABC) transporter BMB171_C3349 ENOG4105BZ1 (ABC) transporter BMB171_C3352 ENOG4105CV1 Transketolase (EC 2.2.1.1) BMB171_C3356 ENOG4108HW3 (ABC) transporter BMB171_C3357 ENOG4105CGH 5'-nucleotidase BMB171_C3359 ENOG4108SVB resolvase BMB171_C3363 ENOG4105K7K Transcriptional regulator BMB171_C3364 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BMB171_C3368 ENOG4105E4C Lytic transglycosylase catalytic BMB171_C3369 ENOG41065S2 pneumococcal vaccine antigen BMB171_C3377 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BMB171_C3378 ENOG4105C5F glutamine synthetase BMB171_C3379 ENOG4105KV4 Transcriptional regulator BMB171_C3380 ENOG4105CXI aluminum resistance protein BMB171_C3381 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BMB171_C3382 ENOG4105EN6 Membrane BMB171_C3383 ENOG4106F1P AAA ATPase, central domain protein BMB171_C3389 ENOG41069ER domain protein BMB171_C3390 ENOG4105DM4 PTS System BMB171_C3391 ENOG4105DE4 1-phosphofructokinase BMB171_C3392 ENOG4105E98 transcriptional regulator DeoR family BMB171_C3393 ENOG4107QW4 alcohol dehydrogenase BMB171_C3394 ENOG4108SJC Membrane BMB171_C3397 ENOG4105C85 amino acid BMB171_C3400 ENOG4105TMB Formate nitrite transporter BMB171_C3401 ENOG4105K70 DNA-binding protein BMB171_C3403 ENOG4105C59 p-type ATPase BMB171_C3404 ENOG410681U heavy metal transport detoxification protein BMB171_C3405 ENOG4105VPX protein, conserved in bacteria BMB171_C3406 ENOG4105NIV Esterase BMB171_C3407 ENOG4105E0A ABC, transporter BMB171_C3412 ENOG4105CGK Exodeoxyribonuclease III BMB171_C3414 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BMB171_C3415 ENOG4105D03 DNA-3-methyladenine glycosylase II BMB171_C3416 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BMB171_C3420 ENOG4105BZU Histidine kinase BMB171_C3427 ENOG41067MG lrgb family BMB171_C3429 ENOG4108S3Y transcriptional regulator BMB171_C3430 ENOG4105CS2 ec 3.2.1.21 BMB171_C3433 ENOG4105F0V Cell wall hydrolase BMB171_C3434 ENOG4107R6R udp-galactopyranose mutase BMB171_C3435 ENOG4105E0M Sulfatase BMB171_C3436 ENOG410890F Dynamin family BMB171_C3441 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BMB171_C3442 ENOG4105DQU oxidoreductase, subunit beta BMB171_C3443 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BMB171_C3444 ENOG4108IGT Dipeptidase BMB171_C3445 ENOG4105MCT stage V sporulation protein S BMB171_C3446 ENOG4105D48 metallophosphoesterase BMB171_C3449 ENOG4105CEV competence damage-inducible protein BMB171_C3450 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BMB171_C3453 ENOG4105XZV Protein of unknown function (DUF3243) BMB171_C3454 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BMB171_C3458 ENOG4105UIB (ABC) transporter BMB171_C3459 ENOG4108JQ9 ABC transporter BMB171_C3460 ENOG4105DIH basic membrane BMB171_C3461 ENOG4105FDP GntR family transcriptional regulator BMB171_C3462 ENOG4105CNU cell division protein FtsK BMB171_C3463 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BMB171_C3465 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BMB171_C3467 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BMB171_C3468 ENOG4108S0H Dipicolinic acid synthetase, b subunit BMB171_C3469 ENOG4105E35 Dipicolinate synthase subunit A BMB171_C3471 ENOG4105C1V Peptidase, M16 BMB171_C3474 ENOG4105DTN riboflavin biosynthesis protein ribF BMB171_C3477 ENOG4105W7A Protein of unknown function (DUF503) BMB171_C3480 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BMB171_C3481 ENOG4105CHV Transcription elongation factor NusA BMB171_C3483 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BMB171_C3484 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BMB171_C3485 ENOG4105DZP Membrane-associated zinc metalloprotease BMB171_C3486 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BMB171_C3487 ENOG4105KNE Phosphatidate cytidylyltransferase BMB171_C3488 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BMB171_C3490 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BMB171_C3496 ENOG4108HE4 integrase family BMB171_C3498 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BMB171_C3499 ENOG4105C79 DNA protecting protein DprA BMB171_C3500 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BMB171_C3503 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BMB171_C3508 ENOG4105VB6 UPF0109 protein BMB171_C3512 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BMB171_C3513 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BMB171_C3516 ENOG4105CHR reductase BMB171_C3517 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BMB171_C3520 ENOG4105CB5 ATP-dependent DNA helicase recG BMB171_C3521 ENOG4105DP4 dak2 domain fusion protein ylov BMB171_C3522 ENOG4108ZAA Alkaline-shock protein BMB171_C3524 ENOG4105FJ0 thiamine BMB171_C3525 ENOG4105DJV ribulose-phosphate 3-epimerase BMB171_C3526 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BMB171_C3527 ENOG4105D9P serine threonine protein kinase BMB171_C3528 ENOG4108ZF3 Phosphatase BMB171_C3529 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BMB171_C3530 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BMB171_C3533 ENOG4105C25 Primosomal protein n' BMB171_C3534 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BMB171_C3538 ENOG4105DSJ YicC domain protein BMB171_C3540 ENOG4105F23 Fibronectin-binding protein BMB171_C3542 ENOG4105DC7 peptidase M24 BMB171_C3547 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BMB171_C3550 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BMB171_C3551 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BMB171_C3553 ENOG4105CD3 dihydroorotase BMB171_C3557 ENOG4105C34 Pseudouridine synthase BMB171_C3560 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BMB171_C3562 ENOG4105DBK s4 domain protein BMB171_C3564 ENOG4105DFA alanine racemase domain protein BMB171_C3565 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BMB171_C3568 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_C3570 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BMB171_C3571 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BMB171_C3573 ENOG4105D4A Cell wall formation (By similarity) BMB171_C3574 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BMB171_C3575 ENOG4105CNI cell division protein FtsW BMB171_C3576 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BMB171_C3578 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BMB171_C3579 ENOG4105CJN penicillin-binding protein BMB171_C3580 ENOG4105CJN penicillin-binding protein BMB171_C3583 ENOG41074B2 UPF0747 protein BMB171_C3588 ENOG4105KNH Nucleic acid-binding protein BMB171_C3590 ENOG41063PX domain protein BMB171_C3591 ENOG4105D78 K07001 NTE family protein BMB171_C3592 ENOG4105H20 Sporulation integral membrane protein YlbJ BMB171_C3594 ENOG4106H78 methyltransferase BMB171_C3598 ENOG4107TB6 phosphoglycerate mutase BMB171_C3601 ENOG4106UY4 Inherit from COG: Scp-like extracellular BMB171_C3611 ENOG4107VFP cytochrome oxidase assembly BMB171_C3612 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BMB171_C3613 ENOG4105CNI cell division protein FtsW BMB171_C3616 ENOG4108IAB Phoh family BMB171_C3620 ENOG4105QA2 BMB171_C3621 ENOG4105CI3 gtp-binding protein typa BMB171_C3623 ENOG4105ECY inositol monophosphatase BMB171_C3627 ENOG4105CXN decarboxylase BMB171_C3635 ENOG4105CPP Dehydrogenase, E1 component BMB171_C3637 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BMB171_C3638 ENOG4108X4Q Hydrolase BMB171_C3640 ENOG4105CN5 Metallo-Beta-Lactamase BMB171_C3641 ENOG4107ZYR domain protein BMB171_C3647 ENOG4108XRC Protein of unknown function (DUF458) BMB171_C3649 ENOG4107IN1 Protein of unknown function (DUF1797) BMB171_C3653 ENOG4105EPM Diguanylate phosphodiesterase BMB171_C3654 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BMB171_C3657 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BMB171_C3659 ENOG4105UIN BMB171_C3667 ENOG4107QYE Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BMB171_C3672 ENOG4108HGU Histidine kinase BMB171_C3674 ENOG4105CHM Aminotransferase BMB171_C3675 ENOG4105FKQ transcriptional regulator BMB171_C3676 ENOG4105EG2 ABC transporter, permease BMB171_C3678 ENOG4107FKK extracellular solute-binding protein family 1 BMB171_C3680 ENOG4105CG3 alpha amylase, catalytic region BMB171_C3687 ENOG4105CHU acetyl-coa acetyltransferase BMB171_C3693 ENOG4105K7K Transcriptional regulator BMB171_C3694 ENOG4105DTD Dehydrogenase BMB171_C3697 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BMB171_C3698 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BMB171_C3700 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate BMB171_C3703 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BMB171_C3706 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BMB171_C3708 ENOG4105BZU Histidine kinase BMB171_C3711 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BMB171_C3714 ENOG4105CID antiterminator BMB171_C3716 ENOG4105FDP GntR family transcriptional regulator BMB171_C3718 ENOG4105CE4 GlcNAc 6-P deacetylase BMB171_C3725 ENOG4107ZE5 PPIases accelerate the folding of proteins BMB171_C3726 ENOG4105PTM secreted protein BMB171_C3727 ENOG4105J7I hydrolase BMB171_C3729 ENOG4105G6R Stage v sporulation protein ae BMB171_C3731 ENOG4105CZ3 stage V sporulation protein ad BMB171_C3732 ENOG41090VF Stage v sporulation protein ac BMB171_C3736 ENOG4105C8J )-transporter BMB171_C3737 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_C3739 ENOG41082AN stage II sporulation protein BMB171_C3740 ENOG4105DZ1 carboxypeptidase BMB171_C3741 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BMB171_C3742 ENOG4105DVE abc transporter atp-binding protein BMB171_C3749 ENOG4105D7N magnesium and cobalt transport protein CorA BMB171_C3755 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BMB171_C3757 ENOG4105I3K Ferric uptake regulator, Fur family BMB171_C3758 ENOG4105MZ9 stage II sporulation protein m BMB171_C3763 ENOG4105CPC Aldo Keto reductase BMB171_C3765 ENOG4105RHY Pfam:UPF0157 BMB171_C3769 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BMB171_C3771 ENOG4105ETE Transcriptional regulator (LacI family BMB171_C3772 ENOG4108YM7 Gcn5-related n-acetyltransferase BMB171_C3775 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BMB171_C3776 ENOG4108R6K riboflavin synthase, subunit alpha BMB171_C3781 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BMB171_C3782 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BMB171_C3784 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BMB171_C3785 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BMB171_C3787 ENOG4105DFD Na H antiporter BMB171_C3788 ENOG4105CGH 5'-nucleotidase BMB171_C3791 ENOG4105DBV ornithine carbamoyltransferase BMB171_C3794 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BMB171_C3797 ENOG4108IXY short-chain dehydrogenase reductase BMB171_C3798 ENOG41069FQ Metallo-beta-lactamase superfamily BMB171_C3799 ENOG4105II7 pyrroline-5-carboxylate reductase BMB171_C3800 ENOG4105EJQ L-serine dehydratase BMB171_C3803 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BMB171_C3805 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BMB171_C3808 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BMB171_C3809 ENOG4105D9U N-acetyltransferase BMB171_C3810 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BMB171_C3811 ENOG4108QEG Membrane BMB171_C3812 ENOG4105CDA abc transporter atp-binding protein BMB171_C3813 ENOG4105E5Q amino acid AbC transporter BMB171_C3814 ENOG4108HW3 (ABC) transporter BMB171_C3816 ENOG4105G7B Protein of unknown function (DUF2992) BMB171_C3818 ENOG4108QY0 Membrane BMB171_C3820 ENOG4105C7S Dehydrogenase BMB171_C3821 ENOG4105CPP Dehydrogenase, E1 component BMB171_C3824 ENOG4105CKM Branched-chain carboxylic acid kinase BMB171_C3825 ENOG4107RDP Dehydrogenase BMB171_C3827 ENOG4108JUB Transcriptional regulator BMB171_C3829 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BMB171_C3832 ENOG4107QQR Sporulation BMB171_C3833 ENOG4105S1Z Stage IV sporulation protein B BMB171_C3835 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BMB171_C3836 ENOG4105DX0 Hemolysin A BMB171_C3838 ENOG4105CTB Polyprenyl synthetase BMB171_C3841 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BMB171_C3843 ENOG4108ZSR alkaline shock protein BMB171_C3844 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BMB171_C3848 ENOG410644B Stage III sporulation protein af BMB171_C3850 ENOG4105KQ4 Stage iii sporulation protein ad BMB171_C3851 ENOG4105KR5 Stage iii sporulation protein BMB171_C3852 ENOG4105CD2 stage iii sporulation protein aa BMB171_C3856 ENOG4105DC7 peptidase M24 BMB171_C3857 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BMB171_C3859 ENOG4105CBJ Metal-dependent enzyme BMB171_C3861 ENOG4107YBY Hydrolase BMB171_C3866 ENOG41082GG biotin lipoate A B protein ligase BMB171_C3867 ENOG4105WZW rhodanese family BMB171_C3872 ENOG41080TC multidrug resistance protein BMB171_C3879 ENOG4105C0D helicase BMB171_C3886 ENOG4105D03 DNA-3-methyladenine glycosylase II BMB171_C3893 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BMB171_C3898 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BMB171_C3909 ENOG4106855 Competence protein BMB171_C3914 ENOG4107R6U sodium dicarboxylate symporter BMB171_C3921 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BMB171_C3922 ENOG4105C3R Methionine synthase BMB171_C3924 ENOG4105C28 cystathionine BMB171_C3925 ENOG4105C28 cystathionine BMB171_C3929 ENOG4105C5X domain protein BMB171_C3931 ENOG4105DKQ ROK family BMB171_C3933 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BMB171_C3935 ENOG4108UTW Plays a role in the regulation of phosphate uptake BMB171_C3936 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BMB171_C3937 ENOG4105C8U phosphate abc transporter BMB171_C3938 ENOG4105C8U phosphate abc transporter BMB171_C3939 ENOG4105EXS phosphate abc transporter BMB171_C3940 ENOG4107RF6 penicillin-binding protein BMB171_C3942 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BMB171_C3946 ENOG4105N80 Ferric uptake regulator, Fur family BMB171_C3948 ENOG4105FDK ABC transporter BMB171_C3949 ENOG4108JYZ YitT family BMB171_C3954 ENOG4105EGD dinuclear metal center protein, YbgI family BMB171_C3957 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_C3958 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BMB171_C3959 ENOG4107XJU UPF0178 protein BMB171_C3965 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BMB171_C3966 ENOG4105KG3 cytidine deaminase BMB171_C3967 ENOG4107YR5 Diacylglycerol kinase BMB171_C3968 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BMB171_C3969 ENOG4105CTJ Metal Dependent Phosphohydrolase BMB171_C3970 ENOG4105C9A Phoh family BMB171_C3972 ENOG41068P3 sporulation protein YqfC BMB171_C3973 ENOG4105KTH gatB Yqey BMB171_C3975 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BMB171_C3976 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BMB171_C3982 ENOG4105CSA Coproporphyrinogen iii oxidase BMB171_C3983 ENOG4105KVH Transcriptional regulator BMB171_C3987 ENOG4105TQK DNA polymerase iii, delta' subunit BMB171_C3989 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BMB171_C3990 ENOG4108UK2 deaminase BMB171_C3991 ENOG4105KQC Competence protein BMB171_C3993 ENOG4105DXX methyltransferase BMB171_C3995 ENOG4108WF2 Metal Dependent Phosphohydrolase BMB171_C3997 ENOG410812S Rna-binding protein BMB171_C3999 ENOG4105CQW ribosome biogenesis GTPase YqeH BMB171_C4000 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BMB171_C4002 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_C4005 ENOG4108TVJ Nitroreductase BMB171_C4009 ENOG4105G6Z alkaline phosphatase BMB171_C4010 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BMB171_C4011 ENOG4108MUZ hydrolase BMB171_C4018 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BMB171_C4020 ENOG4105MIR Phenylalanine 4-monooxygenase BMB171_C4022 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BMB171_C4029 ENOG4105S6R Iron-hydroxamate transporter permease subunit BMB171_C4030 ENOG4108V5C ABC transporter BMB171_C4032 ENOG4108EKI Dehydrogenase BMB171_C4033 ENOG4105C28 cystathionine BMB171_C4039 ENOG4107XRG penicillin-binding protein BMB171_C4041 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BMB171_C4043 ENOG4105CFP Peptidase U32 BMB171_C4044 ENOG4105XYU peptidase (U32 family) BMB171_C4045 ENOG4108VQJ O-methyltransferase BMB171_C4046 ENOG4105HHA aminodeoxychorismate lyase BMB171_C4050 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BMB171_C4052 ENOG4105C02 permease BMB171_C4055 ENOG41060CR BMB171_C4058 ENOG4105C7H Helicase, RecD TraA family BMB171_C4060 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BMB171_C4061 ENOG4105C3J Cysteine desulfurase BMB171_C4063 ENOG4105D1H recombination factor protein RarA BMB171_C4064 ENOG4108VCI transcription factor, rsfa family BMB171_C4065 ENOG4105CUZ uba thif-type nad fad binding protein BMB171_C4067 ENOG4105CUT histidyl-tRNA synthetase BMB171_C4069 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BMB171_C4070 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BMB171_C4072 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BMB171_C4073 ENOG41076HS cation diffusion facilitator family transporter BMB171_C4074 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BMB171_C4076 ENOG4105CKP Polysaccharide Biosynthesis Protein BMB171_C4077 ENOG4108QG2 Membrane BMB171_C4078 ENOG4105VIE preprotein translocase, subunit YajC BMB171_C4083 ENOG4108HUF Transporter BMB171_C4090 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BMB171_C4091 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BMB171_C4092 ENOG4108IYU L-aspartate oxidase BMB171_C4095 ENOG4108RPX mosc domain containing protein BMB171_C4096 ENOG4105CQC Prephenate dehydratase BMB171_C4100 ENOG4105C19 ABC transporter BMB171_C4101 ENOG4105EWM Histidine kinase BMB171_C4103 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BMB171_C4106 ENOG4105X36 (ribosomal) protein BMB171_C4108 ENOG4105C03 ribonuclease BMB171_C4111 ENOG4107QMS site-determining protein BMB171_C4114 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BMB171_C4115 ENOG4105DFF Rod shape-determining protein mreb BMB171_C4117 ENOG4108Z03 MAF-like protein BMB171_C4119 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BMB171_C4120 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BMB171_C4122 ENOG41068KH stage VI sporulation protein D BMB171_C4124 ENOG4105D52 delta-aminolevulinic acid dehydratase BMB171_C4129 ENOG4105K56 Transcriptional regulator BMB171_C4133 ENOG4108IUQ atp-dependent protease BMB171_C4137 ENOG4108QCI YvbH-like oligomerisation region BMB171_C4138 ENOG4105M59 Phosphodiesterase, mj0936 family BMB171_C4139 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BMB171_C4141 ENOG4108XJQ germination protein BMB171_C4143 ENOG4108PCX Major Facilitator BMB171_C4145 ENOG4105KBX Transcriptional regulator, TetR family BMB171_C4147 ENOG4105PFC Transcriptional regulator BMB171_C4149 ENOG4105DZC cytosine deaminase BMB171_C4150 ENOG41067S9 phage shock protein C, PspC BMB171_C4153 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BMB171_C4154 ENOG4108Z40 Transcriptional regulator BMB171_C4155 ENOG4105RHA ABC transporter, permease BMB171_C4156 ENOG4108IUX (ABC) transporter BMB171_C4157 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BMB171_C4158 ENOG4105ER2 Ompa motb domain protein BMB171_C4159 ENOG4105E14 MotA TolQ exbB proton channel BMB171_C4160 ENOG4108VXD carboxy-peptidase BMB171_C4162 ENOG4105E33 succinate dehydrogenase BMB171_C4164 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BMB171_C4166 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BMB171_C4167 ENOG4105K63 Thioredoxin BMB171_C4168 ENOG4105C10 Electron transfer flavoprotein BMB171_C4169 ENOG4105BZJ Electron transfer flavoprotein BMB171_C4170 ENOG41060WC Enoyl-CoA hydratase BMB171_C4171 ENOG4107Z3H Transcriptional regulator, TetR family BMB171_C4172 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_C4174 ENOG4105J76 Periplasmic binding protein BMB171_C4175 ENOG4105S6R Iron-hydroxamate transporter permease subunit BMB171_C4183 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BMB171_C4186 ENOG4105DR4 Methyltransferase BMB171_C4188 ENOG4105KFN sortase, SrtB family BMB171_C4189 ENOG4105E0A ABC, transporter BMB171_C4192 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BMB171_C4194 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BMB171_C4197 ENOG4105FE9 pseudouridine synthase BMB171_C4199 ENOG4105DCG PHP domain protein BMB171_C4202 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BMB171_C4205 ENOG4105C5S asparaginyl-tRNA synthetase BMB171_C4206 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BMB171_C4208 ENOG4108RWN rrna methyltransferase BMB171_C4212 ENOG4105C0R drug resistance transporter emrb qaca subfamily BMB171_C4213 ENOG4105CW7 secretion protein, HlyD family BMB171_C4214 ENOG4108JGH Tetr family transcriptional regulator BMB171_C4215 ENOG4105CN9 Peptidase m42 family protein BMB171_C4218 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BMB171_C4219 ENOG4105C22 threonyL-tRNA synthetase BMB171_C4220 ENOG4108TDW sporulation protein YtxC BMB171_C4224 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BMB171_C4226 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BMB171_C4227 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BMB171_C4229 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BMB171_C4230 ENOG4105C2M dna polymerase I BMB171_C4231 ENOG4105BZU Histidine kinase BMB171_C4232 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BMB171_C4235 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BMB171_C4236 ENOG4108HMX isocitrate dehydrogenase (NADP) BMB171_C4237 ENOG4105BZN citrate synthase BMB171_C4239 ENOG4108REF Sporulation integral membrane protein ytvi BMB171_C4244 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BMB171_C4245 ENOG4105C6K Malic enzyme BMB171_C4246 ENOG4105C0B DNA polymerase III (alpha subunit) BMB171_C4247 ENOG4105VV2 BMB171_C4249 ENOG4105SFS phosphoesterase RecJ domain protein BMB171_C4255 ENOG4105DC7 peptidase M24 BMB171_C4260 ENOG4105Z7P Acetyltransferase (GNAT) family BMB171_C4261 ENOG41082W1 Cupin 2, conserved barrel domain protein BMB171_C4265 ENOG4107YZX Universal stress protein BMB171_C4269 ENOG4105CH7 arginosuccinase BMB171_C4273 ENOG4108JYZ YitT family BMB171_C4277 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BMB171_C4279 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BMB171_C4280 ENOG4105KBJ sporulation protein ytfj BMB171_C4283 ENOG4105EFZ amidohydrolase BMB171_C4285 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BMB171_C4290 ENOG4105RQF LysR family Transcriptional regulator BMB171_C4292 ENOG4105U5Y Transcriptional regulator BMB171_C4294 ENOG4105C28 cystathionine BMB171_C4296 ENOG4108IBT Inherit from COG: transposase BMB171_C4301 ENOG4108UW5 maltose o-acetyltransferase BMB171_C4303 ENOG4105F1V Acetoin utilization protein BMB171_C4304 ENOG4105W87 Cbs domain BMB171_C4305 ENOG4105DGU Histone deacetylase BMB171_C4307 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BMB171_C4309 ENOG4107SNB ankyrin repeat protein YahD BMB171_C4310 ENOG4105EP9 oxidoreductase BMB171_C4314 ENOG4105ETE Transcriptional regulator (LacI family BMB171_C4315 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BMB171_C4319 ENOG4105C88 aminopeptidase BMB171_C4324 ENOG4105K7K Transcriptional regulator BMB171_C4329 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BMB171_C4331 ENOG4108VDD TRNA binding domain protein BMB171_C4337 ENOG4105C8F Beta-lactamase domain protein BMB171_C4340 ENOG4108V15 phosphotransferase enzyme family BMB171_C4341 ENOG4108IUM Glycogen debranching enzyme BMB171_C4343 ENOG4107QSE Dipeptidase BMB171_C4346 ENOG4105CBX hi0933 family BMB171_C4352 ENOG4108VJ1 Transcriptional regulator (CarD family BMB171_C4353 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BMB171_C4354 ENOG4105CSC Glucose uptake protein BMB171_C4357 ENOG4108ZAF Molybdopterin BMB171_C4358 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BMB171_C4359 ENOG4105CVM Molybdenum cofactor synthesis domain protein BMB171_C4361 ENOG4105D06 uba thif-type nad fad binding protein BMB171_C4362 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BMB171_C4370 ENOG41085GJ domain protein BMB171_C4371 ENOG4105DWV Homoserine O-trans-acetylase BMB171_C4373 ENOG4108B31 Spore germination protein BMB171_C4378 ENOG4105C8T Leucyl-tRNA synthetase BMB171_C4379 ENOG410605W Major Facilitator BMB171_C4380 ENOG4107S91 Sodium hydrogen exchanger BMB171_C4381 ENOG4105NCW Trka-c domain protein BMB171_C4384 ENOG4105C19 ABC transporter BMB171_C4388 ENOG4105N5T Radical SAM Protein BMB171_C4395 ENOG4105E8V Alpha Beta Hydrolase Fold protein BMB171_C4396 ENOG4108Z0R Transferase BMB171_C4397 ENOG4105YVM Phosphoesterase, PA-phosphatase related BMB171_C4398 ENOG4105BZF Glycosyl transferase (Group 1 BMB171_C4400 ENOG4105EPU Molybdenum cofactor synthesis domain protein BMB171_C4401 ENOG4108MK9 spermidine N(1)-acetyltransferase BMB171_C4410 ENOG4107XGZ Hydrolase BMB171_C4411 ENOG4105E98 transcriptional regulator DeoR family BMB171_C4414 ENOG4105BZU Histidine kinase BMB171_C4415 ENOG4105BZU Histidine kinase BMB171_C4417 ENOG4107S9D Alpha beta hydrolase BMB171_C4418 ENOG4107T7U Sulfatase BMB171_C4420 ENOG4105D2X ABC transporter substrate-binding protein BMB171_C4422 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BMB171_C4432 ENOG4108V2W Carbonate dehydratase BMB171_C4433 ENOG4105C4M (Ubiquinol oxidase) subunit I BMB171_C4434 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BMB171_C4441 ENOG41087YS Phage shock protein A BMB171_C4445 ENOG4105BZU Histidine kinase BMB171_C4446 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C4451 ENOG4108UGV hypoxanthine phosphoribosyltransferase BMB171_C4452 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BMB171_C4462 ENOG4105C19 ABC transporter BMB171_C4464 ENOG4107ZTW SNARE associated Golgi BMB171_C4467 ENOG4105C19 ABC transporter BMB171_C4468 ENOG41086D8 Transcriptional regulator BMB171_C4473 ENOG41082BM Transcriptional regulator, arsr family BMB171_C4481 ENOG4105C6Z Gluconate BMB171_C4482 ENOG4105FDP GntR family transcriptional regulator BMB171_C4486 ENOG41069H0 dihydroorotase EC 3.5.2.3 BMB171_C4490 ENOG4105DTQ mandelate racemase muconate lactonizing BMB171_C4491 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_C4492 ENOG4108IPT Naphthoate synthase BMB171_C4493 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BMB171_C4494 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BMB171_C4495 ENOG4105E4F Isochorismate synthase BMB171_C4496 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BMB171_C4498 ENOG4105VEQ Cold shock protein BMB171_C4505 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BMB171_C4506 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BMB171_C4508 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BMB171_C4510 ENOG4105KT7 mgtC SapB transporter BMB171_C4511 ENOG4107PBV potassium channel BMB171_C4514 ENOG4105WG9 Conserved Protein BMB171_C4516 ENOG4105CHM Aminotransferase BMB171_C4517 ENOG4108ZB6 transcriptional regulator AsnC family BMB171_C4518 ENOG4105C5I Dehydrogenase BMB171_C4519 ENOG4108MUZ hydrolase BMB171_C4521 ENOG4105C87 Aminotransferase class I and II BMB171_C4524 ENOG4105Y38 Kinase-associated protein B BMB171_C4526 ENOG4107R3E Citrate transporter BMB171_C4529 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BMB171_C4530 ENOG4105KA0 thioesterase Superfamily protein BMB171_C4533 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BMB171_C4536 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BMB171_C4537 ENOG41069ER domain protein BMB171_C4540 ENOG4105CEP NADH dehydrogenase BMB171_C4547 ENOG4105EWC Purine nucleoside phosphorylase BMB171_C4550 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BMB171_C4556 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BMB171_C4557 ENOG4105C4B ABC transporter, permease BMB171_C4558 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BMB171_C4564 ENOG41083MR nifu domain-containing protein BMB171_C4567 ENOG4108W5N phosphatidylglycerophosphatase a BMB171_C4569 ENOG4105DYS nad(p)h dehydrogenase (quinone) BMB171_C4571 ENOG4105D4U had-superfamily hydrolase, subfamily iia BMB171_C4574 ENOG4105CBT Fructose-1,6-bisphosphatase BMB171_C4576 ENOG4105MMD transcriptional regulator BMB171_C4577 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BMB171_C4578 ENOG4107TXC Transcriptional regulator BMB171_C4579 ENOG41090T1 Membrane BMB171_C4584 ENOG4105FAA peptidase M23 BMB171_C4586 ENOG4105KZD Domain of unknown function (DUF1805) BMB171_C4587 ENOG4107R8B 5'-nucleotidase BMB171_C4588 ENOG4105DIW FeS assembly protein SUFB BMB171_C4589 ENOG4108UNV SUF system FeS assembly protein, NifU family BMB171_C4590 ENOG4105C9B Cysteine desulfurase BMB171_C4591 ENOG4105JRK feS assembly protein SufD BMB171_C4592 ENOG4105C3K feS assembly ATPase SufC BMB171_C4593 ENOG4105D01 (LipO)protein BMB171_C4594 ENOG4105D01 (LipO)protein BMB171_C4595 ENOG4108UMI ABC transporter, permease BMB171_C4601 ENOG41080E8 Transcriptional regulator, Spx MgsR family BMB171_C4605 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BMB171_C4610 ENOG4108W8B Beta-lactamase domain protein BMB171_C4611 ENOG4105C1G acyl-Coa dehydrogenase BMB171_C4612 ENOG4105CHU acetyl-coa acetyltransferase BMB171_C4615 ENOG4105DZ1 carboxypeptidase BMB171_C4620 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BMB171_C4623 ENOG4108SUT Major Facilitator Superfamily BMB171_C4624 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BMB171_C4627 ENOG4107R7I amino acid BMB171_C4631 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BMB171_C4632 ENOG4107AYK membrAne BMB171_C4638 ENOG4107ZTW SNARE associated Golgi BMB171_C4641 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BMB171_C4642 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C4643 ENOG4105BZU Histidine kinase BMB171_C4646 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BMB171_C4649 ENOG4105C8Q Methyl-accepting chemotaxis BMB171_C4650 ENOG4105VG1 fes assembly suf system protein BMB171_C4651 ENOG4105D4Y metalloprotease BMB171_C4655 ENOG4107T5V SNARE associated Golgi BMB171_C4656 ENOG4107S91 Sodium hydrogen exchanger BMB171_C4657 ENOG4105NCW Trka-c domain protein BMB171_C4659 ENOG4108RMU ferritin dps family protein BMB171_C4661 ENOG4108URH decarboxylase BMB171_C4663 ENOG41090A1 ferritin BMB171_C4665 ENOG4105D9N nucleoside BMB171_C4666 ENOG4105D9N nucleoside BMB171_C4669 ENOG4108RYK Nad-dependent epimerase dehydratase BMB171_C4672 ENOG4105CV8 reductase BMB171_C4673 ENOG4105F27 Major Facilitator BMB171_C4674 ENOG4105KVH Transcriptional regulator BMB171_C4677 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BMB171_C4678 ENOG4105D4A Cell wall formation (By similarity) BMB171_C4682 ENOG4105WMR Protein CrcB homolog BMB171_C4686 ENOG4105C5H ABC transporter BMB171_C4687 ENOG4108MK9 spermidine N(1)-acetyltransferase BMB171_C4688 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BMB171_C4693 ENOG4108IPW abc transporter atp-binding protein BMB171_C4694 ENOG4105CM4 permease protein BMB171_C4701 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BMB171_C4703 ENOG4105XZU Preprotein translocase, subunit SecG BMB171_C4704 ENOG41067MG lrgb family BMB171_C4720 ENOG4105EFC phage portal protein HK97 family BMB171_C4724 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BMB171_C4727 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BMB171_C4733 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_C4736 ENOG41090VF Stage v sporulation protein ac BMB171_C4737 ENOG4105CZ3 stage V sporulation protein ad BMB171_C4739 ENOG4108QY0 Membrane BMB171_C4740 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BMB171_C4741 ENOG4105KRI phosphocarrier protein (HPr BMB171_C4743 ENOG4105CHW UPF0052 protein BMB171_C4744 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BMB171_C4745 ENOG4108Z4K mutator MutT protein BMB171_C4747 ENOG4105C3M thioredoxin reductase BMB171_C4749 ENOG4108S4C acetyltransferase BMB171_C4751 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) BMB171_C4753 ENOG41086DT Membrane protein of unknown function BMB171_C4754 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BMB171_C4755 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BMB171_C4757 ENOG4107TXC Transcriptional regulator BMB171_C4761 ENOG4105HMI Membrane BMB171_C4762 ENOG4105DUM transcriptional regulator, lysR family BMB171_C4763 ENOG4108WS4 fmn reductase BMB171_C4766 ENOG4105BZ1 (ABC) transporter BMB171_C4768 ENOG4105CN1 protease BMB171_C4769 ENOG4105CRP Part of the ABC transporter FtsEX involved in BMB171_C4770 ENOG4105CAK Cell division ATP-binding protein ftsE BMB171_C4772 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BMB171_C4775 ENOG4108RDQ ABC transporter BMB171_C4781 ENOG4105MS2 ribosomal subunit Interface protein BMB171_C4782 ENOG4105VEQ Cold shock protein BMB171_C4783 ENOG41081UC Inherit from COG: Competence protein BMB171_C4787 ENOG4105KVH Transcriptional regulator BMB171_C4790 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BMB171_C4791 ENOG4108KGH TRANSCRIPTIONal BMB171_C4792 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BMB171_C4793 ENOG4105C6Y Udp-glucose 6-dehydrogenase BMB171_C4794 ENOG4105ESV Glycosyl transferase, family 4 BMB171_C4796 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BMB171_C4800 ENOG4105F8D glycoside hydrolase family 4 BMB171_C4801 ENOG4105VCP PTS System BMB171_C4802 ENOG4105CK1 PTS System BMB171_C4804 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BMB171_C4805 ENOG4105VCP PTS System BMB171_C4807 ENOG4105VZJ PTS System BMB171_C4815 ENOG4105ECB domain protein BMB171_C4816 ENOG4107RSM transcriptional regulator BMB171_C4822 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BMB171_C4823 ENOG4105DAA L-lactate BMB171_C4825 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BMB171_C4827 ENOG4105E0M Sulfatase BMB171_C4832 ENOG4107R8N Glycosyl transferase, family 2 BMB171_C4834 ENOG4105C94 Transporter BMB171_C4835 ENOG41069ER domain protein BMB171_C4840 ENOG4105KBK Zinc finger, swim domain protein BMB171_C4841 ENOG4105C0D helicase BMB171_C4847 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_C4849 ENOG4107RBB ABC transporter, permease BMB171_C4850 ENOG4105C19 ABC transporter BMB171_C4852 ENOG4105CXY transporter BMB171_C4855 ENOG4105BZU Histidine kinase BMB171_C4856 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C4858 ENOG4108KGH TRANSCRIPTIONal BMB171_C4861 ENOG4105EVB acetyltransferase BMB171_C4862 ENOG4105C1B dTDP-glucose 4-6-dehydratase BMB171_C4864 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BMB171_C4865 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BMB171_C4873 ENOG4105D3Q Sugar transferase BMB171_C4874 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BMB171_C4875 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BMB171_C4876 ENOG4107YJ4 chain length determinant protein BMB171_C4877 ENOG4105HTX biosynthesis protein BMB171_C4878 ENOG4107YJ4 chain length determinant protein BMB171_C4881 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BMB171_C4882 ENOG4105FRN stage II sporulation protein BMB171_C4885 ENOG4105DY9 regulatoR BMB171_C4889 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BMB171_C4890 ENOG4105C8S subunit m BMB171_C4891 ENOG4105D65 subunit l BMB171_C4896 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BMB171_C4897 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BMB171_C4900 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BMB171_C4901 ENOG4105BZU Histidine kinase BMB171_C4911 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BMB171_C4913 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BMB171_C4914 ENOG4108UIC UPF0340 protein BMB171_C4915 ENOG4108YZG isomerase BMB171_C4918 ENOG4108VGI doxx family BMB171_C4919 ENOG4107XC4 flavin reductase domain protein, FMN-binding BMB171_C4922 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BMB171_C4924 ENOG4108ZXQ stage ii sporulation protein r BMB171_C4925 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BMB171_C4926 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BMB171_C4927 ENOG4107104 thymidine kinase BMB171_C4928 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BMB171_C4929 ENOG4105CBT Fructose-1,6-bisphosphatase BMB171_C4930 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BMB171_C4934 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BMB171_C4937 ENOG4105C1G acyl-Coa dehydrogenase BMB171_C4938 ENOG4105C1G acyl-Coa dehydrogenase BMB171_C4939 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BMB171_C4941 ENOG4105DF6 Fe-S oxidoreductase BMB171_C4944 ENOG4105BZU Histidine kinase BMB171_C4947 ENOG4105D4Y metalloprotease BMB171_C4949 ENOG4105BZU Histidine kinase BMB171_C4950 ENOG4105KCT ABC transporter BMB171_C4951 ENOG4108M15 ABC transporter BMB171_C4952 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BMB171_C4954 ENOG4105IIU Aminopeptidase BMB171_C4957 ENOG4105DU6 RNA polymerase BMB171_C4964 ENOG4105CYW agmatinase BMB171_C4966 ENOG4105DXB Major Facilitator superfamily BMB171_C4967 ENOG4107SWG transcriptional regulator MERR family BMB171_C4969 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BMB171_C4970 ENOG4105BZ4 penicillin-binding protein BMB171_C4971 ENOG4108XFG YwhD family BMB171_C4972 ENOG4108Z4T Peptidase M50 BMB171_C4973 ENOG41069HH 4-oxalocrotonate tautomerase BMB171_C4974 ENOG4105DCI Phosphohydrolase BMB171_C4975 ENOG4108MES Periplasmic binding protein BMB171_C4976 ENOG4105E0A ABC, transporter BMB171_C4977 ENOG4105EHG Permease protein BMB171_C4978 ENOG4105DQ5 transport system permease protein BMB171_C4980 ENOG4108VCI transcription factor, rsfa family BMB171_C4981 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BMB171_C4982 ENOG4108IJ2 phosphate acetyltransferase BMB171_C4983 ENOG4107UEZ chlorite dismutase BMB171_C4988 ENOG4107SVH Potassium channel protein BMB171_C4990 ENOG410667J hydrolase BMB171_C4991 ENOG4105VCH membrane BMB171_C4993 ENOG4108TU7 Inherit from COG: (ABC) transporter BMB171_C4994 ENOG4105CJ1 ABC, transporter BMB171_C4995 ENOG41090WU lipolytic protein G-D-S-L family BMB171_C4998 ENOG4105D6E homoserine dehydrogenase BMB171_C4999 ENOG4105CVG Homoserine O-transsuccinylase BMB171_C5003 ENOG4108Y4K DNA-binding transcriptional activator BMB171_C5005 ENOG4105WH1 Two component transcriptional regulator luxr family BMB171_C5006 ENOG4105BZU Histidine kinase BMB171_C5007 ENOG4105DWF phosphomethylpyrimidine kinase BMB171_C5008 ENOG4105BZU Histidine kinase BMB171_C5009 ENOG4105VCD cytoplasmic protein BMB171_C5010 ENOG4105D22 carbon starvation protein BMB171_C5011 ENOG4105DY9 regulatoR BMB171_C5012 ENOG41079KZ Major Facilitator Superfamily BMB171_C5015 ENOG4105CG5 Glycosyl transferase (Group 1 BMB171_C5017 ENOG4105EN6 Membrane BMB171_C5018 ENOG4106YBV Methyl-accepting chemotaxis BMB171_C5020 ENOG4108S4H thioesterase Superfamily protein BMB171_C5021 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BMB171_C5024 ENOG4105K64 Glycosyl transferase, family 2 BMB171_C5027 ENOG4105CKK Glycosyl transferase, family 2 BMB171_C5028 ENOG4105C5H ABC transporter BMB171_C5029 ENOG41067SE Tetr family transcriptional regulator BMB171_C5031 ENOG4105E0X reductase BMB171_C5032 ENOG4106F5Q Membrane BMB171_C5035 ENOG4108NEV two component transcriptional regulator, LytTR family BMB171_C5037 ENOG4107RGD Major Facilitator superfamily BMB171_C5041 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BMB171_C5043 ENOG4105IW1 AmiS UreI transporter BMB171_C5044 ENOG4105CMR udp-glucose 4-epimerase BMB171_C5045 ENOG4108UT2 hemolysin iii BMB171_C5047 ENOG4105C1J atp-dependent rna helicase BMB171_C5048 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BMB171_C5049 ENOG4105DPN Oligoendopeptidase f BMB171_C5059 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BMB171_C5061 ENOG4105C0H protease BMB171_C5062 ENOG4105Q2H domain protein BMB171_C5065 ENOG4105BZU Histidine kinase BMB171_C5066 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_C5067 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BMB171_C5068 ENOG4105CDU Replicative dna helicase BMB171_C5070 ENOG4105BZR domain protein BMB171_C5071 ENOG4108XMW Membrane BMB171_C5073 ENOG4108UUM single-stranded DNA-binding protein BMB171_C5075 ENOG4105C3G gtp-binding protein BMB171_C5077 ENOG4105D8X mechanosensitive ion channel BMB171_C5078 ENOG4108ZDA Sporulation protein YyaC BMB171_C5079 ENOG4105FA0 parb-like partition protein BMB171_C5080 ENOG4107QJE Chromosome Partitioning Protein BMB171_C5083 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BMB171_C5084 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BMB171_C5086 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BMB171_C5226 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BMB171_P0001 ENOG4105EWC Purine nucleoside phosphorylase BMB171_P0003 ENOG4107A6P BMB171_P0005 ENOG4105D9M gamma-glutamylcysteine synthetase BMB171_P0007 ENOG4105C4W S-formylglutathione hydrolase BMB171_P0009 ENOG4105KVH Transcriptional regulator BMB171_P0019 ENOG41086D8 Transcriptional regulator BMB171_P0024 ENOG410900G Protein of unknown function (DUF421) BMB171_P0025 ENOG4108NHD germination protein BMB171_P0033 ENOG4106J6E BMB171_P0040 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BMB171_P0049 ENOG4108SA1 esterase BMB171_P0059 ENOG4105EKQ RNA-directed DNA polymerase BMB171_P0073 ENOG4105TQK DNA polymerase iii, delta' subunit BMB171_P0075 ENOG4105EKQ RNA-directed DNA polymerase BMB171_P0077 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BMB171_P0080 ENOG4105EKQ RNA-directed DNA polymerase BMB171_P0101 ENOG4105EKQ RNA-directed DNA polymerase BMB171_P0105 ENOG4105K4H Nlp p60 protein BMB171_P0121 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 BMB171_P0121 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 BMB171_P0123 ENOG4105W5Q DNA repair protein (RadC BMB171_P0127 ENOG4105DH8 myo-inositol catabolism BMB171_P0131 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin BMB171_P0135 ENOG41067QW Transcriptional regulator BMB171_P0137 ENOG4105C6E dna polymerase iii BMB171_P0138 ENOG4105D7V transposase BMB171_P0141 ENOG4105FA2 dna polymerase iii BMB171_P0142 ENOG4105D7V transposase BMB171_P0145 ENOG4108TF4 von Willebrand factor, type A BMB171_P0146 ENOG4105KRN Transcriptional regulator, abrb family BMB171_P0154 ENOG410780I phosphoprotein phosphatase activity BMB171_P0156 ENOG4107K5X Membrane-bound metal-dependent hydrolase BMB171_P0160 ENOG4105FQP Beta-lactamase BMB171_P0164 ENOG4105C7K acetolactate synthase BMB171_P0165 ENOG4105CEY Amp-dependent synthetase and ligase BMB171_P0169 ENOG4105IBP Cyclic peptide transporter BMB171_P0172 ENOG4105C5H ABC transporter BMB171_P0174 ENOG4105W8Z 4'-phosphopantetheinyl transferase BMB171_P0177 ENOG4105D7V transposase BMB171_P0180 ENOG4105BZU Histidine kinase BMB171_P0194 ENOG4106YBV Methyl-accepting chemotaxis BMB171_P0201 ENOG4105D6J arsenicaL-resistance protein BMB171_P0202 ENOG41082YX Transcriptional regulator, arsr family BMB171_P0207 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BMB171_P0209 ENOG41067QW Transcriptional regulator BMB171_P0210 ENOG4105CJ3 phosphate transporter BMB171_P0211 ENOG41085FC arsR family transcriptional regulator BMB171_P0214 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BMB171_P0222 ENOG4105C59 p-type ATPase BMB171_P0223 ENOG4105VPX protein, conserved in bacteria BMB171_P0224 ENOG4105DSE periplasmic solute binding protein BMB171_P0239 ENOG4105K63 Thioredoxin BMB171_P0241 ENOG4105EAB amino acid AbC transporter BMB171_P0242 ENOG4105E5Q amino acid AbC transporter BMB171_P0243 ENOG4105CDA abc transporter atp-binding protein BMB171_P0245 ENOG4107R16 Multicopper oxidase BMB171_P0246 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_P0247 ENOG4105BZU Histidine kinase BMB171_P0250 ENOG4108ZRV stage ii sporulation protein p BMB171_P0254 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BMB171_P0256 ENOG4108W2Y isochorismatase BMB171_P0258 ENOG4108NHD germination protein BMB171_P0267 ENOG4107XGZ Hydrolase BMB171_P0269 ENOG4105YWU small acid-soluble spore protein