locus-tag	class	description
K8Z33_00005	COG1802	Transcriptional regulator
K8Z33_00005	COG4626	Terminase
K8Z33_00015	COG0740	serine-type endopeptidase activity
K8Z33_00075	COG4824	toxin secretion phage lysis holin
K8Z33_00140	COG1309	transcriptional regulator
K8Z33_00145	COG0488	(ABC) transporter
K8Z33_00195	COG0457	Tetratricopeptide repeat
K8Z33_00215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z33_00235	COG0697	spore germination
K8Z33_00245	COG3397	chitin binding
K8Z33_00250	COG0823	Involved in the tonB-independent uptake of proteins
K8Z33_00260	COG0463	Glycosyl transferase, family 2
K8Z33_00265	COG0463	Glycosyl transferase, family 2
K8Z33_00270	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K8Z33_00280	COG1088	dTDP-glucose 4,6-dehydratase activity
K8Z33_00285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K8Z33_00290	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K8Z33_00305	COG2089	acid synthase
K8Z33_00315	COG4641	Protein conserved in bacteria
K8Z33_00330	COG1252	NADH dehydrogenase
K8Z33_00350	COG0277	FAD linked oxidase domain protein
K8Z33_00355	COG0385	Bile acid
K8Z33_00365	COG0457	Tetratricopeptide repeat
K8Z33_00375	COG0604	alcohol dehydrogenase
K8Z33_00380	COG0640	Transcriptional regulator
K8Z33_00390	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z33_00415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z33_00450	COG1164	Oligoendopeptidase f
K8Z33_00455	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z33_00470	COG1193	negative regulation of DNA recombination
K8Z33_00490	COG0583	DNA-binding transcription factor activity
K8Z33_00520	COG3739	integral membrane protein
K8Z33_00525	COG1247	-acetyltransferase
K8Z33_00535	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z33_00540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z33_00570	COG2814	Major facilitator Superfamily
K8Z33_00575	COG1113	amino acid transport
K8Z33_00580	COG0604	alcohol dehydrogenase
K8Z33_00585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_00615	COG2072	flavoprotein involved in K transport
K8Z33_00650	COG1151	hydroxylamine reductase activity
K8Z33_00695	COG1191	sigma factor activity
K8Z33_00720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K8Z33_00725	COG1733	regulation of RNA biosynthetic process
K8Z33_00730	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z33_00735	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_00745	COG0384	phenazine biosynthesis protein PhzF
K8Z33_00770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_00790	COG0673	inositol 2-dehydrogenase activity
K8Z33_00795	COG2188	Transcriptional regulator
K8Z33_00800	COG1733	regulation of RNA biosynthetic process
K8Z33_00830	COG0814	amino acid
K8Z33_00850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z33_00855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z33_00860	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z33_00865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z33_00870	COG1070	Carbohydrate kinase
K8Z33_00875	COG2706	6-phosphogluconolactonase activity
K8Z33_00880	COG3813	Protein conserved in bacteria
K8Z33_00885	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z33_00900	COG0697	spore germination
K8Z33_00905	COG0789	Transcriptional regulator
K8Z33_00910	COG1253	flavin adenine dinucleotide binding
K8Z33_00940	COG0477	Major facilitator Superfamily
K8Z33_00950	COG0500	methyltransferase
K8Z33_00980	COG0628	permease
K8Z33_01000	COG1136	(ABC) transporter
K8Z33_01010	COG0110	maltose O-acetyltransferase activity
K8Z33_01015	COG0738	Major facilitator superfamily
K8Z33_01020	COG1940	carbohydrate kinase activity
K8Z33_01025	COG0346	lactoylglutathione lyase activity
K8Z33_01035	COG1051	belongs to the nudix hydrolase family
K8Z33_01050	COG2365	Tyrosine phosphatase family
K8Z33_01055	COG1011	Hydrolase
K8Z33_01080	COG1131	(ABC) transporter
K8Z33_01090	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_01120	COG0778	Nitroreductase
K8Z33_01125	COG1733	regulation of RNA biosynthetic process
K8Z33_01145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z33_01150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z33_01160	COG2356	endonuclease I
K8Z33_01165	COG1288	antiporter activity
K8Z33_01170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K8Z33_01220	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z33_01235	COG2031	fatty acid transporter
K8Z33_01245	COG2814	Major facilitator Superfamily
K8Z33_01250	COG1846	Transcriptional regulator
K8Z33_01265	COG0477	Major facilitator Superfamily
K8Z33_01275	COG2843	Capsule synthesis protein
K8Z33_01280	COG1876	peptidase activity
K8Z33_01305	COG5444	nuclease activity
K8Z33_01355	COG4282	regulation of fungal-type cell wall biogenesis
K8Z33_01410	COG2814	Major facilitator Superfamily
K8Z33_01425	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_01425	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_01440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z33_01440	COG2207	Transcriptional regulator
K8Z33_01445	COG0662	Cupin 2, conserved barrel domain protein
K8Z33_01465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z33_01490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_01495	COG2808	Putative FMN-binding domain
K8Z33_01500	COG0456	acetyltransferase
K8Z33_01505	COG1846	Transcriptional regulator
K8Z33_01510	COG2364	Membrane
K8Z33_01520	COG5002	protein histidine kinase activity
K8Z33_01520	COG3850	Histidine kinase
K8Z33_01540	COG0577	efflux transmembrane transporter activity
K8Z33_01560	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z33_01580	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z33_01590	COG2814	Major facilitator Superfamily
K8Z33_01625	COG1136	(ABC) transporter
K8Z33_01635	COG0277	FAD linked oxidase domain protein
K8Z33_01680	COG0745	RESPONSE REGULATOR receiver
K8Z33_01705	COG0346	lactoylglutathione lyase activity
K8Z33_01720	COG1522	sequence-specific DNA binding
K8Z33_01725	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_01730	COG1309	transcriptional regulator
K8Z33_01735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z33_01735	COG3320	Male sterility
K8Z33_01745	COG0825	malonyl-CoA metabolic process
K8Z33_01755	COG1476	TRANSCRIPTIONal
K8Z33_01795	COG0583	DNA-binding transcription factor activity
K8Z33_01805	COG0640	Transcriptional regulator
K8Z33_01810	COG0346	lactoylglutathione lyase activity
K8Z33_01815	COG0798	PFAM Bile acid sodium symporter
K8Z33_01835	COG1121	(ABC) transporter
K8Z33_01840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z33_01845	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z33_01850	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z33_01865	COG5609	conserved protein (DUF2294)
K8Z33_01870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z33_01880	COG0288	reversible hydration of carbon dioxide
K8Z33_01885	COG0415	Belongs to the DNA photolyase family
K8Z33_01905	COG1073	alpha beta
K8Z33_01925	COG0598	Magnesium transport protein CorA
K8Z33_01930	COG1846	Transcriptional regulator
K8Z33_01935	COG0583	DNA-binding transcription factor activity
K8Z33_01955	COG1335	isochorismatase
K8Z33_01965	COG0737	Belongs to the 5'-nucleotidase family
K8Z33_01980	COG2124	cytochrome p450
K8Z33_01990	COG1115	amino acid carrier protein
K8Z33_02000	COG4191	Histidine kinase
K8Z33_02005	COG0784	Response regulator, receiver
K8Z33_02015	COG0531	amino acid
K8Z33_02025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z33_02030	COG0531	amino acid
K8Z33_02035	COG0322	excinuclease ABC activity
K8Z33_02050	COG2207	Transcriptional regulator
K8Z33_02075	COG5002	protein histidine kinase activity
K8Z33_02105	COG1396	sequence-specific DNA binding
K8Z33_02115	COG1027	Aspartate ammonia-lyase
K8Z33_02125	COG1063	alcohol dehydrogenase
K8Z33_02145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_02150	COG3848	Pyruvate phosphate dikinase
K8Z33_02150	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z33_02190	COG3314	Sporulation integral membrane protein YlbJ
K8Z33_02205	COG1960	acyl-CoA dehydrogenase activity
K8Z33_02215	COG0640	Transcriptional regulator
K8Z33_02230	COG1414	Transcriptional regulator
K8Z33_02235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z33_02240	COG1984	allophanate hydrolase subunit 2
K8Z33_02270	COG0768	penicillin binding
K8Z33_02295	COG5002	protein histidine kinase activity
K8Z33_02305	COG1329	Transcriptional regulator
K8Z33_02355	COG0833	amino acid
K8Z33_02365	COG0730	response to heat
K8Z33_02410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_02415	COG0697	spore germination
K8Z33_02420	COG2816	NAD+ diphosphatase activity
K8Z33_02430	COG0456	acetyltransferase
K8Z33_02435	COG2207	Transcriptional regulator
K8Z33_02455	COG1136	(ABC) transporter
K8Z33_02465	COG3831	ATPase activity
K8Z33_02465	COG4884	unkown
K8Z33_02485	COG1846	Transcriptional regulator
K8Z33_02490	COG0778	Nitroreductase
K8Z33_02550	COG0753	catalase activity
K8Z33_02555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z33_02580	COG0714	Associated with various cellular activities
K8Z33_02600	COG0346	lactoylglutathione lyase activity
K8Z33_02605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_02625	COG3655	Transcriptional regulator
K8Z33_02635	COG1785	Belongs to the alkaline phosphatase family
K8Z33_02640	COG2720	vancomycin resistance protein
K8Z33_02650	COG3239	Fatty acid desaturase
K8Z33_02660	COG1690	Belongs to the RtcB family
K8Z33_02670	COG0833	amino acid
K8Z33_02675	COG1414	Transcriptional regulator
K8Z33_02680	COG4187	Peptidase family M20/M25/M40
K8Z33_02685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z33_02700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_02715	COG2329	Antibiotic biosynthesis monooxygenase
K8Z33_02740	COG1070	Carbohydrate kinase
K8Z33_02745	COG2390	Transcriptional regulator
K8Z33_02755	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z33_02765	COG1879	ABC-type sugar transport system periplasmic component
K8Z33_02830	COG1605	Chorismate mutase
K8Z33_02830	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z33_02845	COG0287	Prephenate dehydrogenase
K8Z33_02860	COG1309	transcriptional regulator
K8Z33_02865	COG1033	growth of symbiont in host cell
K8Z33_02865	COG2409	Drug exporters of the RND superfamily
K8Z33_02870	COG0488	(ABC) transporter
K8Z33_02875	COG1368	sulfuric ester hydrolase activity
K8Z33_02880	COG0861	Integral membrane protein TerC family
K8Z33_02910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_02915	COG0346	lactoylglutathione lyase activity
K8Z33_02920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z33_02925	COG4912	Dna alkylation repair
K8Z33_02945	COG2318	DinB family
K8Z33_02950	COG0697	spore germination
K8Z33_02960	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z33_02990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z33_02995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z33_03015	COG0628	permease
K8Z33_03060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z33_03065	COG0436	Aminotransferase
K8Z33_03100	COG2226	methyltransferase
K8Z33_03115	COG2261	transglycosylase associated protein
K8Z33_03140	COG2814	Major facilitator Superfamily
K8Z33_03140	COG0477	Major facilitator Superfamily
K8Z33_03145	COG4533	DNA binding
K8Z33_03150	COG0789	Transcriptional regulator
K8Z33_03155	COG1664	Polymer-forming cytoskeletal
K8Z33_03165	COG2814	Major facilitator Superfamily
K8Z33_03205	COG1307	EDD domain protein, DegV family
K8Z33_03210	COG1164	Oligoendopeptidase f
K8Z33_03235	COG0745	RESPONSE REGULATOR receiver
K8Z33_03240	COG3850	Histidine kinase
K8Z33_03240	COG5002	protein histidine kinase activity
K8Z33_03285	COG0667	Aldo Keto reductase
K8Z33_03300	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z33_03310	COG4166	transmembrane transport
K8Z33_03315	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z33_03325	COG0586	Pfam SNARE associated Golgi protein
K8Z33_03370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z33_03375	COG3938	Belongs to the proline racemase family
K8Z33_03385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z33_03390	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_03395	COG1115	amino acid carrier protein
K8Z33_03400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z33_03415	COG3397	chitin binding
K8Z33_03435	COG4637	Psort location Cytoplasmic, score
K8Z33_03465	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z33_03480	COG3973	AAA domain
K8Z33_03485	COG0456	acetyltransferase
K8Z33_03535	COG2315	Protein conserved in bacteria
K8Z33_03540	COG2267	carboxylic ester hydrolase activity
K8Z33_03540	COG2226	methyltransferase
K8Z33_03545	COG2205	protein histidine kinase activity
K8Z33_03555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K8Z33_03565	COG1819	glycosyl
K8Z33_03570	COG3397	chitin binding
K8Z33_03590	COG2153	protein acetylation
K8Z33_03620	COG0517	IMP dehydrogenase activity
K8Z33_03620	COG4175	Glycine betaine
K8Z33_03625	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z33_03665	COG0456	acetyltransferase
K8Z33_03665	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z33_03670	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_03685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z33_03690	COG0022	dehydrogenase e1 component
K8Z33_03695	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z33_03700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z33_03715	COG1959	2 iron, 2 sulfur cluster binding
K8Z33_03730	COG1349	DNA-binding transcription factor activity
K8Z33_03750	COG3284	Transcriptional regulator
K8Z33_03770	COG1309	transcriptional regulator
K8Z33_03810	COG2959	enzyme of heme biosynthesis
K8Z33_03825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_03860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_03865	COG0697	spore germination
K8Z33_03870	COG0201	protein transport
K8Z33_03875	COG0346	lactoylglutathione lyase activity
K8Z33_03890	COG0737	Belongs to the 5'-nucleotidase family
K8Z33_03895	COG3227	Zinc metalloprotease (Elastase)
K8Z33_03900	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z33_03915	COG0076	glutamate decarboxylase activity
K8Z33_03920	COG0657	acetylesterase activity
K8Z33_03925	COG1073	alpha beta
K8Z33_03935	COG1136	(ABC) transporter
K8Z33_03950	COG5002	protein histidine kinase activity
K8Z33_03955	COG0745	RESPONSE REGULATOR receiver
K8Z33_03960	COG1011	Hydrolase
K8Z33_03985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z33_04000	COG1819	glycosyl
K8Z33_04005	COG1819	glycosyl
K8Z33_04040	COG0322	excinuclease ABC activity
K8Z33_04080	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z33_04100	COG3878	Protein conserved in bacteria
K8Z33_04125	COG1051	belongs to the nudix hydrolase family
K8Z33_04130	COG0592	DNA-directed DNA polymerase activity
K8Z33_04145	COG2223	nitrite transmembrane transporter activity
K8Z33_04155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z33_04165	COG0494	nUDIX hydrolase
K8Z33_04190	COG0697	spore germination
K8Z33_04195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_04220	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z33_04240	COG2814	Major facilitator Superfamily
K8Z33_04285	COG0768	penicillin binding
K8Z33_04290	COG0671	phosphoesterase, PA-phosphatase related
K8Z33_04295	COG0604	alcohol dehydrogenase
K8Z33_04300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z33_04325	COG2169	Transcriptional regulator
K8Z33_04385	COG2205	protein histidine kinase activity
K8Z33_04425	COG1533	DNA photolyase activity
K8Z33_04445	COG1090	epimerase
K8Z33_04460	COG2155	Conserved Protein
K8Z33_04470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z33_04480	COG0415	Belongs to the DNA photolyase family
K8Z33_04490	COG2814	Major facilitator Superfamily
K8Z33_04500	COG0288	reversible hydration of carbon dioxide
K8Z33_04505	COG0640	Transcriptional regulator
K8Z33_04515	COG1181	Belongs to the D-alanine--D-alanine ligase family
K8Z33_04515	COG2918	glutathione biosynthetic process
K8Z33_04525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K8Z33_04535	COG1733	regulation of RNA biosynthetic process
K8Z33_04595	COG1329	Transcriptional regulator
K8Z33_04605	COG0662	Cupin 2, conserved barrel domain protein
K8Z33_04655	COG1794	racemase activity, acting on amino acids and derivatives
K8Z33_04660	COG1819	glycosyl
K8Z33_04670	COG0768	penicillin binding
K8Z33_04675	COG5002	protein histidine kinase activity
K8Z33_04680	COG0561	phosphatase activity
K8Z33_04715	COG2124	cytochrome p450
K8Z33_04775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z33_04785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_04810	COG0577	efflux transmembrane transporter activity
K8Z33_04815	COG1136	(ABC) transporter
K8Z33_04830	COG0488	(ABC) transporter
K8Z33_04835	COG0667	Aldo Keto reductase
K8Z33_04840	COG0583	DNA-binding transcription factor activity
K8Z33_04845	COG2205	protein histidine kinase activity
K8Z33_04850	COG0745	RESPONSE REGULATOR receiver
K8Z33_04860	COG3773	Cell wall hydrolase
K8Z33_04865	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z33_04875	COG3386	PFAM SMP-30 Gluconolaconase
K8Z33_04885	COG0693	protein deglycase activity
K8Z33_04895	COG2323	membrane
K8Z33_04920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_04965	COG1733	regulation of RNA biosynthetic process
K8Z33_04970	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_04980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z33_05010	COG2207	Transcriptional regulator
K8Z33_05015	COG3227	Zinc metalloprotease (Elastase)
K8Z33_05030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z33_05060	COG1686	Belongs to the peptidase S11 family
K8Z33_05095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z33_05100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z33_05105	COG1024	Enoyl-CoA hydratase
K8Z33_05110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z33_05115	COG0511	ligase activity, forming carbon-carbon bonds
K8Z33_05120	COG0439	Biotin carboxylase
K8Z33_05125	COG1960	acyl-CoA dehydrogenase activity
K8Z33_05140	COG1309	transcriptional regulator
K8Z33_05160	COG1408	metallophosphoesterase
K8Z33_05170	COG0768	penicillin binding
K8Z33_05180	COG0768	penicillin binding
K8Z33_05190	COG1595	DNA-templated transcription, initiation
K8Z33_05195	COG0768	penicillin binding
K8Z33_05245	COG1396	sequence-specific DNA binding
K8Z33_05290	COG2814	Major facilitator Superfamily
K8Z33_05295	COG2234	aminopeptidase activity
K8Z33_05305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z33_05320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K8Z33_05325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z33_05330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K8Z33_05340	COG0456	acetyltransferase
K8Z33_05350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_05355	COG0741	lytic transglycosylase activity
K8Z33_05400	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_05430	COG2814	Major facilitator Superfamily
K8Z33_05445	COG1686	Belongs to the peptidase S11 family
K8Z33_05455	COG0730	response to heat
K8Z33_05465	COG2002	toxin-antitoxin pair type II binding
K8Z33_05490	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z33_05535	COG2226	methyltransferase
K8Z33_05545	COG0500	methyltransferase
K8Z33_05545	COG3615	Tellurite resistance protein tehB
K8Z33_05560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_05575	COG1846	Transcriptional regulator
K8Z33_05585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K8Z33_05595	COG2971	BadF BadG BcrA BcrD
K8Z33_05620	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z33_05645	COG1595	DNA-templated transcription, initiation
K8Z33_05650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z33_05680	COG1396	sequence-specific DNA binding
K8Z33_05705	COG1132	(ABC) transporter
K8Z33_05710	COG1132	(ABC) transporter
K8Z33_05725	COG2258	MOSC domain
K8Z33_05730	COG0583	DNA-binding transcription factor activity
K8Z33_05745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z33_05750	COG0583	DNA-binding transcription factor activity
K8Z33_05780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_05790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z33_05815	COG1247	-acetyltransferase
K8Z33_05850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_05870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z33_05915	COG1136	(ABC) transporter
K8Z33_05920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z33_05925	COG1187	pseudouridine synthase activity
K8Z33_05945	COG1115	amino acid carrier protein
K8Z33_05955	COG2318	DinB family
K8Z33_05965	COG0776	regulation of translation
K8Z33_05980	COG2814	Major facilitator Superfamily
K8Z33_05985	COG3251	PFAM MbtH domain protein
K8Z33_05990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z33_05995	COG1535	isochorismatase
K8Z33_05995	COG3433	isochorismatase activity
K8Z33_06000	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z33_06005	COG1169	isochorismate synthase
K8Z33_06010	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_06015	COG2223	nitrite transmembrane transporter activity
K8Z33_06035	COG0419	ATPase involved in DNA repair
K8Z33_06040	COG0420	3'-5' exonuclease activity
K8Z33_06055	COG1024	Enoyl-CoA hydratase
K8Z33_06060	COG1280	lysine exporter protein (LysE YggA)
K8Z33_06070	COG2084	Dehydrogenase
K8Z33_06075	COG1960	acyl-CoA dehydrogenase activity
K8Z33_06080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z33_06085	COG2079	MmgE PrpD family protein
K8Z33_06090	COG0372	Belongs to the citrate synthase family
K8Z33_06095	COG4841	protein insertion into membrane
K8Z33_06100	COG2814	Major facilitator Superfamily
K8Z33_06130	COG0300	oxidoreductase activity
K8Z33_06205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z33_06210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z33_06215	COG0671	phosphoesterase, PA-phosphatase related
K8Z33_06225	COG4991	sh3 domain protein
K8Z33_06225	COG3064	Membrane
K8Z33_06225	COG0515	serine threonine protein kinase
K8Z33_06260	COG1509	lysine 2,3-aminomutase activity
K8Z33_06265	COG3829	transcription factor binding
K8Z33_06270	COG0456	acetyltransferase
K8Z33_06275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z33_06280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z33_06285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z33_06290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z33_06305	COG5506	Protein of unknown function (DUF1694)
K8Z33_06310	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_06315	COG1253	flavin adenine dinucleotide binding
K8Z33_06350	COG1174	glycine betaine transport
K8Z33_06355	COG1125	glycine betaine transport
K8Z33_06355	COG0517	IMP dehydrogenase activity
K8Z33_06390	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z33_06400	COG1070	Carbohydrate kinase
K8Z33_06415	COG1064	alcohol dehydrogenase
K8Z33_06420	COG0384	phenazine biosynthesis protein PhzF
K8Z33_06425	COG1737	Transcriptional regulator
K8Z33_06430	COG2197	response regulator
K8Z33_06435	COG2203	Gaf domain
K8Z33_06435	COG4585	Histidine kinase
K8Z33_06440	COG0668	transmembrane transport
K8Z33_06445	COG1051	belongs to the nudix hydrolase family
K8Z33_06450	COG1335	isochorismatase
K8Z33_06465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z33_06470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z33_06475	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z33_06490	COG0367	asparagine synthase
K8Z33_06495	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z33_06500	COG1999	signal sequence binding
K8Z33_06510	COG1307	EDD domain protein, DegV family
K8Z33_06520	COG0805	protein transport
K8Z33_06530	COG1272	protein, Hemolysin III
K8Z33_06535	COG0204	Acyl-transferase
K8Z33_06545	COG0768	penicillin binding
K8Z33_06575	COG0546	phosphoglycolate phosphatase activity
K8Z33_06590	COG1131	(ABC) transporter
K8Z33_06600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z33_06605	COG3655	Transcriptional regulator
K8Z33_06615	COG0456	acetyltransferase
K8Z33_06625	COG1794	racemase activity, acting on amino acids and derivatives
K8Z33_06635	COG2610	gluconate transmembrane transporter activity
K8Z33_06660	COG0733	neurotransmitter:sodium symporter activity
K8Z33_06665	COG0017	Asparaginyl-tRNA synthetase
K8Z33_06705	COG0018	arginyl-trna synthetase
K8Z33_06710	COG2521	methyltransferase
K8Z33_06710	COG2136	Putative SAM-dependent methyltransferase
K8Z33_06725	COG1413	lyase activity
K8Z33_06735	COG0629	single-stranded DNA binding
K8Z33_06750	COG0488	(ABC) transporter
K8Z33_06755	COG1418	mRNA catabolic process
K8Z33_06770	COG0457	Tetratricopeptide repeat
K8Z33_06790	COG2359	stage V sporulation protein S
K8Z33_06825	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z33_06830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z33_06835	COG2146	nitrite reductase [NAD(P)H] activity
K8Z33_06840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z33_06840	COG1587	Uroporphyrinogen-III synthase
K8Z33_06845	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
K8Z33_06850	COG1648	precorrin-2 dehydrogenase activity
K8Z33_06865	COG2223	nitrite transmembrane transporter activity
K8Z33_06875	COG0314	molybdopterin synthase activity
K8Z33_06880	COG0303	'Molybdopterin
K8Z33_06885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z33_06890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z33_06895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z33_06900	COG2181	nitrate reductase activity
K8Z33_06905	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z33_06910	COG1140	nitrate reductase beta subunit
K8Z33_06915	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z33_06920	COG0714	Associated with various cellular activities
K8Z33_06925	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z33_06930	COG1305	Transglutaminase-like
K8Z33_06935	COG0386	Belongs to the glutathione peroxidase family
K8Z33_06945	COG0426	domain, Protein
K8Z33_06945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z33_06955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K8Z33_06965	COG1595	DNA-templated transcription, initiation
K8Z33_06970	COG0604	alcohol dehydrogenase
K8Z33_06980	COG0346	lactoylglutathione lyase activity
K8Z33_06985	COG1082	Xylose isomerase domain protein TIM barrel
K8Z33_07005	COG2226	methyltransferase
K8Z33_07030	COG3874	Sporulation protein YtfJ
K8Z33_07040	COG4974	Belongs to the 'phage' integrase family
K8Z33_07195	COG0456	acetyltransferase
K8Z33_07225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_07230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_07235	COG1819	glycosyl
K8Z33_07250	COG4106	trans-aconitate 2-methyltransferase activity
K8Z33_07255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z33_07265	COG2814	Major facilitator Superfamily
K8Z33_07270	COG1846	Transcriptional regulator
K8Z33_07275	COG0561	phosphatase activity
K8Z33_07285	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z33_07300	COG2211	Major facilitator Superfamily
K8Z33_07315	COG1876	peptidase activity
K8Z33_07325	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z33_07345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z33_07350	COG1114	Component of the transport system for branched-chain amino acids
K8Z33_07375	COG1253	flavin adenine dinucleotide binding
K8Z33_07380	COG2839	Protein conserved in bacteria
K8Z33_07385	COG0702	epimerase
K8Z33_07400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z33_07410	COG1607	acyl-coa hydrolase
K8Z33_07415	COG3689	TIGRFAM TIGR03943 family protein
K8Z33_07420	COG0701	Predicted permease
K8Z33_07430	COG2244	polysaccharide biosynthetic process
K8Z33_07435	COG0586	Pfam SNARE associated Golgi protein
K8Z33_07440	COG1051	belongs to the nudix hydrolase family
K8Z33_07445	COG5337	Spore coat protein CotH
K8Z33_07455	COG0406	alpha-ribazole phosphatase activity
K8Z33_07470	COG4166	transmembrane transport
K8Z33_07480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z33_07490	COG0702	epimerase
K8Z33_07500	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z33_07505	COG0456	acetyltransferase
K8Z33_07510	COG0523	cobalamin synthesis protein
K8Z33_07515	COG4989	oxidoreductase activity
K8Z33_07520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_07525	COG1231	oxidoreductase activity
K8Z33_07535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z33_07550	COG0783	Belongs to the Dps family
K8Z33_07555	COG3949	Membrane
K8Z33_07570	COG0840	transmembrane signaling receptor activity
K8Z33_07600	COG0667	Aldo Keto reductase
K8Z33_07605	COG0640	Transcriptional regulator
K8Z33_07610	COG1404	Belongs to the peptidase S8 family
K8Z33_07615	COG2002	toxin-antitoxin pair type II binding
K8Z33_07655	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z33_07665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_07670	COG1279	arginine transmembrane transporter activity
K8Z33_07675	COG2814	Major facilitator Superfamily
K8Z33_07685	COG1082	Xylose isomerase domain protein TIM barrel
K8Z33_07695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z33_07715	COG1247	-acetyltransferase
K8Z33_07720	COG1285	pathogenesis
K8Z33_07735	COG1316	TRANSCRIPTIONal
K8Z33_07760	COG0460	homoserine dehydrogenase
K8Z33_07790	COG4122	O-methyltransferase activity
K8Z33_07800	COG0300	oxidoreductase activity
K8Z33_07805	COG5002	protein histidine kinase activity
K8Z33_07810	COG0745	RESPONSE REGULATOR receiver
K8Z33_07815	COG1132	(ABC) transporter
K8Z33_07825	COG0791	NLP P60 protein
K8Z33_07825	COG1388	LysM domain
K8Z33_07840	COG1686	Belongs to the peptidase S11 family
K8Z33_07880	COG1216	Glycosyl transferase, family 2
K8Z33_07890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z33_07895	COG4988	ABC transporter
K8Z33_07900	COG1294	oxidase, subunit
K8Z33_07905	COG1271	oxidase subunit
K8Z33_07935	COG0583	DNA-binding transcription factor activity
K8Z33_07955	COG0411	ABC transporter
K8Z33_07965	COG0523	cobalamin synthesis protein
K8Z33_07970	COG1231	oxidoreductase activity
K8Z33_07980	COG0628	permease
K8Z33_07990	COG0778	Nitroreductase
K8Z33_07995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z33_08000	COG1959	2 iron, 2 sulfur cluster binding
K8Z33_08005	COG0583	DNA-binding transcription factor activity
K8Z33_08010	COG0697	spore germination
K8Z33_08015	COG4549	nuclear export factor GLE1
K8Z33_08020	COG1276	copper resistance
K8Z33_08020	COG2372	response to copper ion
K8Z33_08030	COG1114	Component of the transport system for branched-chain amino acids
K8Z33_08050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z33_08060	COG2132	Multicopper oxidase
K8Z33_08070	COG0006	proline dipeptidase activity
K8Z33_08080	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z33_08115	COG0295	cytidine deaminase activity
K8Z33_08120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z33_08125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_08135	COG2390	Transcriptional regulator
K8Z33_08140	COG1309	transcriptional regulator
K8Z33_08155	COG0456	acetyltransferase
K8Z33_08170	COG2309	aminopeptidase activity
K8Z33_08190	COG0531	amino acid
K8Z33_08195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z33_08210	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z33_08230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_08235	COG4166	transmembrane transport
K8Z33_08255	COG0427	acetyl-CoA hydrolase
K8Z33_08260	COG3279	Response regulator of the LytR AlgR family
K8Z33_08275	COG3384	dioxygenase
K8Z33_08280	COG2814	Major facilitator Superfamily
K8Z33_08305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z33_08325	COG0028	Belongs to the TPP enzyme family
K8Z33_08330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z33_08340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z33_08360	COG2323	membrane
K8Z33_08365	COG5566	PFAM Mor transcription activator
K8Z33_08375	COG0733	neurotransmitter:sodium symporter activity
K8Z33_08395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z33_08400	COG2223	nitrite transmembrane transporter activity
K8Z33_08405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z33_08415	COG0477	Major facilitator Superfamily
K8Z33_08425	COG1695	Transcriptional regulator
K8Z33_08440	COG2814	Major facilitator Superfamily
K8Z33_08485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z33_08490	COG0784	Response regulator, receiver
K8Z33_08495	COG4191	Histidine kinase
K8Z33_08500	COG0281	malic enzyme
K8Z33_08505	COG1027	Aspartate ammonia-lyase
K8Z33_08515	COG0528	UMP kinase activity
K8Z33_08520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z33_08535	COG1131	(ABC) transporter
K8Z33_08570	COG2733	membrane
K8Z33_08590	COG0457	Tetratricopeptide repeat
K8Z33_08605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z33_08610	COG0785	Cytochrome C biogenesis protein
K8Z33_08630	COG3340	Belongs to the peptidase S51 family
K8Z33_08635	COG0534	Mate efflux family protein
K8Z33_08665	COG0789	Transcriptional regulator
K8Z33_08670	COG1757	Na H antiporter
K8Z33_08675	COG0438	transferase activity, transferring glycosyl groups
K8Z33_08675	COG1216	Glycosyl transferase, family 2
K8Z33_08685	COG0701	Predicted permease
K8Z33_08690	COG0523	cobalamin synthesis protein
K8Z33_08730	COG0367	asparagine synthase
K8Z33_08740	COG1846	Transcriptional regulator
K8Z33_08760	COG0406	alpha-ribazole phosphatase activity
K8Z33_08795	COG1234	tRNA 3'-trailer cleavage
K8Z33_08815	COG0583	DNA-binding transcription factor activity
K8Z33_08840	COG1215	transferase activity, transferring glycosyl groups
K8Z33_08845	COG2329	Antibiotic biosynthesis monooxygenase
K8Z33_08875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z33_08880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z33_08885	COG4786	Flagellar basal body rod
K8Z33_08890	COG1419	protein localization to endoplasmic reticulum
K8Z33_08895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z33_08900	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z33_08910	COG1987	bacterial-type flagellum assembly
K8Z33_08915	COG1338	Plays a role in the flagellum-specific transport system
K8Z33_08925	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z33_08925	COG1776	CheC inhibitor of MCP methylation
K8Z33_08930	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z33_08940	COG0741	lytic transglycosylase activity
K8Z33_08945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z33_08965	COG0784	Response regulator, receiver
K8Z33_08965	COG0835	chemotaxis
K8Z33_08980	COG1749	Flagellar hook protein flgE
K8Z33_09000	COG1157	protein secretion by the type III secretion system
K8Z33_09010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z33_09015	COG1766	The M ring may be actively involved in energy transduction
K8Z33_09025	COG1558	bacterial-type flagellum-dependent cell motility
K8Z33_09030	COG1815	bacterial-type flagellum-dependent cell motility
K8Z33_09050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z33_09055	COG1256	bacterial-type flagellum assembly
K8Z33_09075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z33_09095	COG0643	Histidine kinase
K8Z33_09095	COG2198	Histidine kinase
K8Z33_09100	COG2201	protein-glutamate methylesterase activity
K8Z33_09105	COG1360	Flagellar Motor Protein
K8Z33_09110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z33_09120	COG1923	regulation of RNA biosynthetic process
K8Z33_09160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z33_09165	COG2323	membrane
K8Z33_09175	COG0789	Transcriptional regulator
K8Z33_09175	COG4978	Transcriptional regulator
K8Z33_09185	COG0475	glutathione-regulated potassium exporter activity
K8Z33_09195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z33_09200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z33_09220	COG1280	lysine exporter protein (LysE YggA)
K8Z33_09225	COG3403	YqcI/YcgG family
K8Z33_09260	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z33_09280	COG0454	-acetyltransferase
K8Z33_09295	COG0438	transferase activity, transferring glycosyl groups
K8Z33_09300	COG1215	transferase activity, transferring glycosyl groups
K8Z33_09315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z33_09325	COG3944	biosynthesis protein
K8Z33_09340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z33_09355	COG0754	glutathionylspermidine amidase activity
K8Z33_09390	COG0456	acetyltransferase
K8Z33_09400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z33_09410	COG2311	Membrane
K8Z33_09415	COG2233	PERMEase
K8Z33_09425	COG0024	Methionine aminopeptidase
K8Z33_09430	COG3173	Aminoglycoside phosphotransferase
K8Z33_09440	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z33_09445	COG1199	ATP-dependent helicase activity
K8Z33_09455	COG0116	Belongs to the methyltransferase superfamily
K8Z33_09510	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z33_09510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z33_09520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z33_09525	COG3935	DnaD domain protein
K8Z33_09545	COG1199	ATP-dependent helicase activity
K8Z33_09545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z33_09580	COG0438	transferase activity, transferring glycosyl groups
K8Z33_09600	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z33_09605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_09615	COG2738	Putative neutral zinc metallopeptidase
K8Z33_09630	COG4347	Protein of unknown function (DUF1405)
K8Z33_09635	COG2010	Cytochrome c
K8Z33_09635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z33_09640	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z33_09660	COG0457	Tetratricopeptide repeat
K8Z33_09685	COG0142	geranyltranstransferase activity
K8Z33_09695	COG0142	geranyltranstransferase activity
K8Z33_09710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z33_09780	COG0252	asparaginase activity
K8Z33_09785	COG0492	ferredoxin-NADP+ reductase activity
K8Z33_09805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z33_09815	COG0789	Transcriptional regulator
K8Z33_09820	COG1408	metallophosphoesterase
K8Z33_09830	COG1266	CAAX protease self-immunity
K8Z33_09835	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z33_09845	COG1141	Ferredoxin
K8Z33_09850	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z33_09860	COG4942	peptidase
K8Z33_09865	COG2096	Adenosyltransferase
K8Z33_09870	COG5002	protein histidine kinase activity
K8Z33_09875	COG0745	RESPONSE REGULATOR receiver
K8Z33_09880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z33_09885	COG1333	cytochrome c biogenesis protein
K8Z33_09895	COG1187	pseudouridine synthase activity
K8Z33_09900	COG0700	Nucleoside recognition
K8Z33_09905	COG2715	membrane protein required for spore maturation
K8Z33_09910	COG1686	Belongs to the peptidase S11 family
K8Z33_09915	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z33_09930	COG0392	lysyltransferase activity
K8Z33_09930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z33_09945	COG5002	protein histidine kinase activity
K8Z33_09950	COG0582	viral genome integration into host DNA
K8Z33_09960	COG1801	Protein of unknown function DUF72
K8Z33_09965	COG3852	Histidine kinase
K8Z33_09980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z33_09985	COG1392	Phosphate transport regulator
K8Z33_09990	COG0306	phosphate transporter
K8Z33_09995	COG0730	response to heat
K8Z33_10045	COG1114	Component of the transport system for branched-chain amino acids
K8Z33_10055	COG2197	response regulator
K8Z33_10060	COG4585	Histidine kinase
K8Z33_10065	COG4758	membrane
K8Z33_10080	COG1757	Na H antiporter
K8Z33_10105	COG0733	neurotransmitter:sodium symporter activity
K8Z33_10110	COG1648	precorrin-2 dehydrogenase activity
K8Z33_10130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z33_10135	COG0529	Catalyzes the synthesis of activated sulfate
K8Z33_10155	COG0019	diaminopimelate decarboxylase activity
K8Z33_10165	COG1368	sulfuric ester hydrolase activity
K8Z33_10170	COG1183	phosphatidylcholine synthase activity
K8Z33_10185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z33_10260	COG0440	acetolactate synthase activity
K8Z33_10265	COG0028	Belongs to the TPP enzyme family
K8Z33_10270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z33_10290	COG3874	Sporulation protein YtfJ
K8Z33_10295	COG4709	membrane
K8Z33_10300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z33_10305	COG1301	dicarboxylic acid transport
K8Z33_10315	COG1846	Transcriptional regulator
K8Z33_10370	COG0716	FMN binding
K8Z33_10395	COG1696	Membrane protein involved in D-alanine export
K8Z33_10405	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z33_10410	COG2070	2-Nitropropane dioxygenase
K8Z33_10415	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z33_10425	COG1335	isochorismatase
K8Z33_10435	COG1522	sequence-specific DNA binding
K8Z33_10455	COG1131	(ABC) transporter
K8Z33_10465	COG1131	(ABC) transporter
K8Z33_10470	COG1725	Transcriptional regulator
K8Z33_10475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z33_10480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z33_10485	COG1780	Probably involved in ribonucleotide reductase function
K8Z33_10515	COG4873	Protein conserved in bacteria
K8Z33_10530	COG0720	synthase
K8Z33_10540	COG5002	protein histidine kinase activity
K8Z33_10550	COG2318	DinB family
K8Z33_10560	COG1846	Transcriptional regulator
K8Z33_10565	COG3852	Histidine kinase
K8Z33_10575	COG2861	carbohydrate metabolic process
K8Z33_10585	COG0235	Class ii aldolase
K8Z33_10595	COG1349	DNA-binding transcription factor activity
K8Z33_10620	COG3842	ATPase activity
K8Z33_10625	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z33_10640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z33_10650	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z33_10655	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_10675	COG2030	dehydratase
K8Z33_10685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z33_10690	COG0861	Integral membrane protein TerC family
K8Z33_10695	COG2116	formate transmembrane transporter activity
K8Z33_10705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z33_10725	COG2186	Transcriptional regulator
K8Z33_10730	COG5002	protein histidine kinase activity
K8Z33_10735	COG0745	RESPONSE REGULATOR receiver
K8Z33_10745	COG3835	regulator
K8Z33_10750	COG0277	FAD linked oxidase domain protein
K8Z33_10755	COG0247	lactate metabolic process
K8Z33_10760	COG2340	Cysteine-rich secretory protein family
K8Z33_10770	COG0564	pseudouridine synthase activity
K8Z33_10780	COG2409	Drug exporters of the RND superfamily
K8Z33_10785	COG0671	phosphoesterase, PA-phosphatase related
K8Z33_10795	COG1177	transmembrane transport
K8Z33_10800	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z33_10810	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_10845	COG0681	Belongs to the peptidase S26 family
K8Z33_10850	COG1686	Belongs to the peptidase S11 family
K8Z33_10860	COG2226	methyltransferase
K8Z33_10885	COG1668	transmembrane transport
K8Z33_10890	COG4152	abc transporter atp-binding protein
K8Z33_10920	COG1476	TRANSCRIPTIONal
K8Z33_10930	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z33_10985	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z33_10990	COG1620	l-lactate permease
K8Z33_11025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z33_11025	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z33_11035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z33_11040	COG5492	domain, Protein
K8Z33_11055	COG2382	esterase
K8Z33_11065	COG2153	protein acetylation
K8Z33_11110	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z33_11125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z33_11165	COG1216	Glycosyl transferase, family 2
K8Z33_11170	COG0772	Belongs to the SEDS family
K8Z33_11185	COG0564	pseudouridine synthase activity
K8Z33_11195	COG2357	RelA SpoT domain protein
K8Z33_11205	COG4116	CYTH
K8Z33_11210	COG2346	COG2346, Truncated hemoglobins
K8Z33_11225	COG1164	Oligoendopeptidase f
K8Z33_11235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z33_11245	COG0861	Integral membrane protein TerC family
K8Z33_11260	COG4166	transmembrane transport
K8Z33_11265	COG0534	Mate efflux family protein
K8Z33_11270	COG4608	Belongs to the ABC transporter superfamily
K8Z33_11275	COG0444	Belongs to the ABC transporter superfamily
K8Z33_11280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z33_11285	COG0601	transmembrane transport
K8Z33_11290	COG4166	transmembrane transport
K8Z33_11300	COG0180	Tryptophanyl-tRNA synthetase
K8Z33_11310	COG5504	Zn-dependent protease
K8Z33_11315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z33_11320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z33_11335	COG2267	carboxylic ester hydrolase activity
K8Z33_11355	COG0561	phosphatase activity
K8Z33_11370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_11425	COG3209	COG3209 Rhs family protein
K8Z33_11430	COG2996	Protein conserved in bacteria
K8Z33_11450	COG0004	ammonium transporteR
K8Z33_11455	COG0753	catalase activity
K8Z33_11465	COG0367	asparagine synthase
K8Z33_11490	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z33_11550	COG0398	Pfam SNARE associated Golgi protein
K8Z33_11555	COG4903	ComK protein
K8Z33_11570	COG1278	Cold shock
K8Z33_11585	COG2224	Isocitrate lyase
K8Z33_11590	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z33_11600	COG3693	PFAM glycoside hydrolase, family 10
K8Z33_11610	COG0840	transmembrane signaling receptor activity
K8Z33_11615	COG0501	Belongs to the peptidase M48B family
K8Z33_11635	COG0745	RESPONSE REGULATOR receiver
K8Z33_11640	COG2205	protein histidine kinase activity
K8Z33_11650	COG2207	Transcriptional regulator
K8Z33_11650	COG3708	Transcriptional regulator
K8Z33_11655	COG1595	DNA-templated transcription, initiation
K8Z33_11665	COG1078	dGTPase activity
K8Z33_11670	COG1408	metallophosphoesterase
K8Z33_11675	COG1073	alpha beta
K8Z33_11735	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_11745	COG0095	Lipoate-protein ligase
K8Z33_11750	COG1234	tRNA 3'-trailer cleavage
K8Z33_11760	COG1609	Transcriptional regulator
K8Z33_11785	COG1511	domain protein
K8Z33_11790	COG1309	transcriptional regulator
K8Z33_11815	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z33_11830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z33_11835	COG2329	Antibiotic biosynthesis monooxygenase
K8Z33_11845	COG3402	PFAM membrane-flanked domain
K8Z33_11850	COG0697	spore germination
K8Z33_11885	COG3428	Bacterial PH domain
K8Z33_11890	COG3402	PFAM membrane-flanked domain
K8Z33_11900	COG1309	transcriptional regulator
K8Z33_11915	COG4473	ABC transporter
K8Z33_11920	COG1131	(ABC) transporter
K8Z33_11925	COG0537	adenosine 5'-monophosphoramidase activity
K8Z33_11930	COG4980	gas vesicle protein
K8Z33_11955	COG3973	AAA domain
K8Z33_11985	COG1695	Transcriptional regulator
K8Z33_11990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z33_12000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z33_12005	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z33_12015	COG3620	sequence-specific DNA binding
K8Z33_12020	COG2140	Oxalate decarboxylase
K8Z33_12045	COG2267	carboxylic ester hydrolase activity
K8Z33_12060	COG0346	lactoylglutathione lyase activity
K8Z33_12065	COG0346	lactoylglutathione lyase activity
K8Z33_12070	COG1280	lysine exporter protein (LysE YggA)
K8Z33_12085	COG4717	serine-type aminopeptidase activity
K8Z33_12090	COG0420	3'-5' exonuclease activity
K8Z33_12110	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z33_12165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z33_12170	COG2208	phosphoserine phosphatase activity
K8Z33_12180	COG1191	sigma factor activity
K8Z33_12255	COG2373	Large extracellular alpha-helical protein
K8Z33_12315	COG2376	Dihydroxyacetone kinase
K8Z33_12325	COG2376	Dihydroxyacetone kinase
K8Z33_12335	COG0640	Transcriptional regulator
K8Z33_12340	COG2814	Major facilitator Superfamily
K8Z33_12350	COG1183	phosphatidylcholine synthase activity
K8Z33_12410	COG1073	alpha beta
K8Z33_12495	COG0477	Major facilitator Superfamily
K8Z33_12525	COG0305	Participates in initiation and elongation during chromosome replication
K8Z33_12545	COG0210	DNA helicase
K8Z33_12585	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z33_12590	COG4565	transcriptional regulatory protein
K8Z33_12595	COG3290	protein histidine kinase activity
K8Z33_12600	COG0477	Major facilitator Superfamily
K8Z33_12655	COG3157	Type VI secretion system effector, Hcp
K8Z33_12715	COG2814	Major facilitator Superfamily
K8Z33_12720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z33_12735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z33_12755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_12765	COG4608	Belongs to the ABC transporter superfamily
K8Z33_12770	COG0444	Belongs to the ABC transporter superfamily
K8Z33_12775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z33_12780	COG0601	transmembrane transport
K8Z33_12815	COG1363	Peptidase, m42
K8Z33_12835	COG1024	Enoyl-CoA hydratase
K8Z33_12855	COG2244	polysaccharide biosynthetic process
K8Z33_12860	COG0659	secondary active sulfate transmembrane transporter activity
K8Z33_12870	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_12875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z33_12880	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_12880	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_12890	COG0561	phosphatase activity
K8Z33_12905	COG3527	Alpha-acetolactate decarboxylase
K8Z33_12910	COG0028	Belongs to the TPP enzyme family
K8Z33_12940	COG0189	ligase activity
K8Z33_12955	COG1126	abc transporter atp-binding protein
K8Z33_12960	COG0765	amino acid transport
K8Z33_12965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z33_12970	COG1132	(ABC) transporter
K8Z33_12975	COG1132	(ABC) transporter
K8Z33_12980	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_12985	COG0531	amino acid
K8Z33_12995	COG0753	catalase activity
K8Z33_12995	COG0693	protein deglycase activity
K8Z33_13000	COG0693	protein deglycase activity
K8Z33_13025	COG1733	regulation of RNA biosynthetic process
K8Z33_13030	COG2814	Major facilitator Superfamily
K8Z33_13035	COG1309	transcriptional regulator
K8Z33_13050	COG0789	Transcriptional regulator
K8Z33_13055	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_13065	COG1522	sequence-specific DNA binding
K8Z33_13085	COG2259	Doxx family
K8Z33_13095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z33_13095	COG1263	PTS System
K8Z33_13105	COG1737	Transcriptional regulator
K8Z33_13115	COG0475	glutathione-regulated potassium exporter activity
K8Z33_13120	COG0531	amino acid
K8Z33_13155	COG0586	Pfam SNARE associated Golgi protein
K8Z33_13190	COG3546	catalase activity
K8Z33_13195	COG1114	Component of the transport system for branched-chain amino acids
K8Z33_13210	COG5522	Integral membrane protein (intg_mem_TP0381)
K8Z33_13220	COG1136	(ABC) transporter
K8Z33_13225	COG0577	efflux transmembrane transporter activity
K8Z33_13230	COG3584	3D domain protein
K8Z33_13230	COG1388	LysM domain
K8Z33_13255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z33_13260	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z33_13265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z33_13265	COG3711	transcriptional antiterminator
K8Z33_13280	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8Z33_13285	COG0604	alcohol dehydrogenase
K8Z33_13290	COG1316	TRANSCRIPTIONal
K8Z33_13300	COG0730	response to heat
K8Z33_13305	COG2210	Belongs to the sulfur carrier protein TusA family
K8Z33_13315	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z33_13315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z33_13320	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z33_13325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_13325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z33_13330	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z33_13330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z33_13335	COG1937	Protein conserved in bacteria
K8Z33_13355	COG2719	SpoVR family
K8Z33_13360	COG0778	Nitroreductase
K8Z33_13420	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_13425	COG2252	PERMEase
K8Z33_13440	COG1846	Transcriptional regulator
K8Z33_13445	COG2814	Major facilitator Superfamily
K8Z33_13450	COG2205	protein histidine kinase activity
K8Z33_13490	COG0351	phosphomethylpyrimidine kinase
K8Z33_13495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z33_13505	COG2104	thiamine diphosphate biosynthetic process
K8Z33_13510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z33_13515	COG0352	thiamine-phosphate diphosphorylase activity
K8Z33_13520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z33_13525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z33_13530	COG1116	anion transmembrane transporter activity
K8Z33_13535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z33_13555	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z33_13670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z33_13680	COG0581	inorganic phosphate transmembrane transporter activity
K8Z33_13685	COG0573	inorganic phosphate transmembrane transporter activity
K8Z33_13690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z33_13695	COG1918	ferrous iron import across plasma membrane
K8Z33_13695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z33_13700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z33_13705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z33_13720	COG0531	amino acid
K8Z33_13725	COG0697	spore germination
K8Z33_13730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z33_13745	COG4990	cell redox homeostasis
K8Z33_13750	COG0833	amino acid
K8Z33_13760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z33_13775	COG0569	domain protein
K8Z33_13775	COG0475	glutathione-regulated potassium exporter activity
K8Z33_13785	COG2153	protein acetylation
K8Z33_13800	COG2252	PERMEase
K8Z33_13805	COG1113	amino acid transport
K8Z33_13820	COG1114	Component of the transport system for branched-chain amino acids
K8Z33_13825	COG3104	oligopeptide transport
K8Z33_13845	COG1476	TRANSCRIPTIONal
K8Z33_13850	COG3583	domain protein
K8Z33_13850	COG3584	3D domain protein
K8Z33_13855	COG0840	transmembrane signaling receptor activity
K8Z33_13905	COG1063	alcohol dehydrogenase
K8Z33_13935	COG1879	ABC-type sugar transport system periplasmic component
K8Z33_13940	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z33_13955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z33_13960	COG1609	Transcriptional regulator
K8Z33_13965	COG0477	Major facilitator Superfamily
K8Z33_13970	COG1846	Transcriptional regulator
K8Z33_13975	COG2271	Major facilitator Superfamily
K8Z33_13990	COG0659	secondary active sulfate transmembrane transporter activity
K8Z33_14015	COG5002	protein histidine kinase activity
K8Z33_14020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z33_14025	COG2378	regulation of single-species biofilm formation
K8Z33_14035	COG1595	DNA-templated transcription, initiation
K8Z33_14050	COG0833	amino acid
K8Z33_14055	COG0765	amino acid transport
K8Z33_14060	COG0765	amino acid transport
K8Z33_14065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z33_14070	COG1126	abc transporter atp-binding protein
K8Z33_14075	COG1115	amino acid carrier protein
K8Z33_14085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z33_14090	COG0697	spore germination
K8Z33_14105	COG0366	Alpha amylase catalytic
K8Z33_14110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z33_14110	COG1263	PTS System
K8Z33_14115	COG2188	Transcriptional regulator
K8Z33_14120	COG0531	amino acid
K8Z33_14140	COG0714	Associated with various cellular activities
K8Z33_14145	COG4548	von Willebrand factor, type A
K8Z33_14155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z33_14160	COG0156	8-amino-7-oxononanoate synthase activity
K8Z33_14175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_14180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_14185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z33_14190	COG3104	oligopeptide transport
K8Z33_14205	COG1620	l-lactate permease
K8Z33_14210	COG1027	Aspartate ammonia-lyase
K8Z33_14215	COG1253	flavin adenine dinucleotide binding
K8Z33_14220	COG0346	lactoylglutathione lyase activity
K8Z33_14225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_14230	COG1316	TRANSCRIPTIONal
K8Z33_14235	COG2720	vancomycin resistance protein
K8Z33_14255	COG3227	Zinc metalloprotease (Elastase)
K8Z33_14270	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z33_14275	COG2217	Heavy metal translocating P-type atpase
K8Z33_14280	COG0640	Transcriptional regulator
K8Z33_14285	COG0531	amino acid
K8Z33_14300	COG2427	Protein of unknown function (DUF1641)
K8Z33_14305	COG3383	formate dehydrogenase (NAD+) activity
K8Z33_14310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z33_14330	COG5002	protein histidine kinase activity
K8Z33_14340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_14345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_14360	COG0281	malic enzyme
K8Z33_14365	COG3493	citrate carrier protein
K8Z33_14370	COG4565	transcriptional regulatory protein
K8Z33_14375	COG3290	protein histidine kinase activity
K8Z33_14385	COG4990	cell redox homeostasis
K8Z33_14395	COG5002	protein histidine kinase activity
K8Z33_14400	COG0745	RESPONSE REGULATOR receiver
K8Z33_14405	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z33_14415	COG0395	ABC-type sugar transport system, permease component
K8Z33_14420	COG1175	transmembrane transport
K8Z33_14425	COG3842	ATPase activity
K8Z33_14430	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z33_14455	COG2851	Citrate transporter
K8Z33_14460	COG4565	transcriptional regulatory protein
K8Z33_14465	COG3290	protein histidine kinase activity
K8Z33_14475	COG2268	Band 7 protein
K8Z33_14480	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z33_14490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z33_14505	COG2766	serine protein kinase
K8Z33_14515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z33_14540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z33_14660	COG0735	belongs to the Fur family
K8Z33_14665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z33_14685	COG4555	ABC transporter
K8Z33_14695	COG0067	glutamate synthase
K8Z33_14695	COG0069	glutamate synthase activity
K8Z33_14695	COG0070	glutamate synthase
K8Z33_14700	COG4129	membrane
K8Z33_14705	COG1132	(ABC) transporter
K8Z33_14730	COG1194	a g-specific adenine glycosylase
K8Z33_14735	COG1988	membrane-bound metal-dependent
K8Z33_14765	COG1090	epimerase
K8Z33_14770	COG1228	amidohydrolase
K8Z33_14790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z33_14805	COG0463	Glycosyl transferase, family 2
K8Z33_14810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z33_14810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z33_14820	COG0463	Glycosyl transferase, family 2
K8Z33_14835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z33_14840	COG1263	PTS System
K8Z33_14840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z33_14870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z33_14875	COG0833	amino acid
K8Z33_14885	COG3829	transcription factor binding
K8Z33_14905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z33_14910	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z33_14930	COG0535	radical SAM domain protein
K8Z33_14940	COG0387	Pfam Sodium calcium exchanger
K8Z33_14945	COG3871	stress protein (general stress protein 26)
K8Z33_14960	COG0586	Pfam SNARE associated Golgi protein
K8Z33_14970	COG0681	Belongs to the peptidase S26 family
K8Z33_14980	COG0697	spore germination
K8Z33_14985	COG2217	Heavy metal translocating P-type atpase
K8Z33_14990	COG1295	ribonuclease BN
K8Z33_15000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z33_15015	COG3853	Toxic anion resistance protein (TelA)
K8Z33_15025	COG0861	Integral membrane protein TerC family
K8Z33_15030	COG2310	stress, protein
K8Z33_15035	COG2310	stress, protein
K8Z33_15040	COG2310	stress, protein
K8Z33_15070	COG2270	Major facilitator Superfamily
K8Z33_15115	COG0488	(ABC) transporter
K8Z33_15120	COG1116	anion transmembrane transporter activity
K8Z33_15125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z33_15130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z33_15150	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z33_15180	COG1263	PTS System
K8Z33_15180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z33_15180	COG2190	(PTS) system
K8Z33_15185	COG0366	Alpha amylase catalytic
K8Z33_15190	COG0277	FAD linked oxidase domain protein
K8Z33_15200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z33_15205	COG0549	Belongs to the carbamate kinase family
K8Z33_15230	COG0840	transmembrane signaling receptor activity
K8Z33_15235	COG1126	abc transporter atp-binding protein
K8Z33_15240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z33_15245	COG0765	amino acid transport
K8Z33_15255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z33_15255	COG0723	plastoquinol--plastocyanin reductase activity
K8Z33_15260	COG2814	Major facilitator Superfamily
K8Z33_15265	COG3541	Predicted nucleotidyltransferase
K8Z33_15285	COG5002	protein histidine kinase activity
K8Z33_15310	COG0166	Belongs to the GPI family
K8Z33_15325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z33_15330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_15335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_15350	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K8Z33_15360	COG0450	alkyl hydroperoxide reductase
K8Z33_15375	COG1473	amidohydrolase
K8Z33_15380	COG1757	Na H antiporter
K8Z33_15405	COG4807	Protein conserved in bacteria
K8Z33_15410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z33_15420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_15435	COG2309	aminopeptidase activity
K8Z33_15445	COG2076	Multidrug Resistance protein
K8Z33_15450	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_15460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z33_15465	COG0546	phosphoglycolate phosphatase activity
K8Z33_15470	COG1597	lipid kinase activity
K8Z33_15490	COG4682	membrane
K8Z33_15495	COG1846	Transcriptional regulator
K8Z33_15500	COG0003	Pfam Anion-transporting ATPase
K8Z33_15515	COG1464	Belongs to the NlpA lipoprotein family
K8Z33_15520	COG2011	ABC-type metal ion transport system permease component
K8Z33_15530	COG1335	isochorismatase
K8Z33_15545	COG4851	CamS sex pheromone cAM373 precursor
K8Z33_15555	COG0210	DNA helicase
K8Z33_15580	COG0151	Belongs to the GarS family
K8Z33_15590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z33_15600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z33_15615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z33_15625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z33_15630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z33_15635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z33_15655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z33_15680	COG0745	RESPONSE REGULATOR receiver
K8Z33_15685	COG2205	protein histidine kinase activity
K8Z33_15730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_15750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z33_15775	COG5002	protein histidine kinase activity
K8Z33_15785	COG2252	PERMEase
K8Z33_15795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z33_15810	COG2946	Replication initiation factor
K8Z33_15820	COG1674	ftsk spoiiie
K8Z33_15940	COG0582	viral genome integration into host DNA
K8Z33_15955	COG1266	CAAX protease self-immunity
K8Z33_15970	COG0488	(ABC) transporter
K8Z33_15980	COG0456	acetyltransferase
K8Z33_15985	COG1214	PFAM Peptidase M22, glycoprotease
K8Z33_15990	COG0802	atpase or kinase
K8Z33_16090	COG2183	response to ionizing radiation
K8Z33_16095	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z33_16100	COG0864	Transcriptional regulator
K8Z33_16105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z33_16110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z33_16120	COG0705	Rhomboid family
K8Z33_16125	COG4294	response to UV
K8Z33_16135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z33_16145	COG2814	Major facilitator Superfamily
K8Z33_16150	COG0531	amino acid
K8Z33_16160	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z33_16165	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z33_16190	COG0561	phosphatase activity
K8Z33_16195	COG4608	Belongs to the ABC transporter superfamily
K8Z33_16200	COG0444	Belongs to the ABC transporter superfamily
K8Z33_16205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z33_16210	COG0601	transmembrane transport
K8Z33_16215	COG0747	negative chemotaxis
K8Z33_16225	COG0488	(ABC) transporter
K8Z33_16245	COG5298	Protein conserved in bacteria
K8Z33_16260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_16270	COG1609	Transcriptional regulator
K8Z33_16280	COG0204	Acyl-transferase
K8Z33_16295	COG0697	spore germination
K8Z33_16310	COG1910	domain protein
K8Z33_16315	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z33_16320	COG4149	molybdate abc transporter
K8Z33_16335	COG0656	L-ascorbic acid biosynthetic process
K8Z33_16340	COG4166	transmembrane transport
K8Z33_16345	COG4166	transmembrane transport
K8Z33_16360	COG4166	transmembrane transport
K8Z33_16365	COG4608	Belongs to the ABC transporter superfamily
K8Z33_16370	COG0444	Belongs to the ABC transporter superfamily
K8Z33_16375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z33_16380	COG0601	transmembrane transport
K8Z33_16400	COG2814	Major facilitator Superfamily
K8Z33_16410	COG2271	Major facilitator Superfamily
K8Z33_16415	COG0277	FAD linked oxidase domain protein
K8Z33_16425	COG0604	alcohol dehydrogenase
K8Z33_16430	COG1464	Belongs to the NlpA lipoprotein family
K8Z33_16435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z33_16440	COG2011	ABC-type metal ion transport system permease component
K8Z33_16445	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_16480	COG4856	YbbR-like protein
K8Z33_16485	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z33_16565	COG0726	polysaccharide deacetylase
K8Z33_16570	COG2194	sulfuric ester hydrolase activity
K8Z33_16580	COG0489	protein tyrosine kinase activity
K8Z33_16585	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z33_16610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z33_16645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z33_16655	COG0024	Methionine aminopeptidase
K8Z33_16665	COG0201	protein transport
K8Z33_16725	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z33_16765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K8Z33_16770	COG0051	transcription antitermination factor activity, RNA binding
K8Z33_16790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z33_16795	COG1358	cellular component organization or biogenesis
K8Z33_16800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K8Z33_16810	COG2813	Specifically methylates the guanine in position
K8Z33_16830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z33_16835	COG0250	Participates in transcription elongation, termination and antitermination
K8Z33_16840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z33_16855	COG3688	RNA-binding protein containing a PIN domain
K8Z33_16860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z33_16875	COG1045	serine acetyltransferase
K8Z33_16895	COG4956	integral membrane protein (PIN domain superfamily)
K8Z33_16905	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z33_16910	COG0542	response to heat
K8Z33_16920	COG3880	PFAM UvrB UvrC protein
K8Z33_17010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z33_17015	COG1396	sequence-specific DNA binding
K8Z33_17020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z33_17025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z33_17030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z33_17035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z33_17040	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z33_17045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z33_17050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z33_17065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z33_17070	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z33_17080	COG2208	phosphoserine phosphatase activity
K8Z33_17095	COG1098	S1 RNA binding domain
K8Z33_17115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z33_17120	COG3956	TIGRFAM MazG family protein
K8Z33_17125	COG2244	polysaccharide biosynthetic process
K8Z33_17130	COG2002	toxin-antitoxin pair type II binding
K8Z33_17135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z33_17165	COG0251	oxidation-reduction process
K8Z33_17170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z33_17185	COG4466	Protein conserved in bacteria
K8Z33_17205	COG0084	hydrolase, TatD family'
K8Z33_17215	COG2002	toxin-antitoxin pair type II binding
K8Z33_17220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z33_17230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z33_17240	COG1774	PSP1 C-terminal conserved region
K8Z33_17245	COG0470	DNA polymerase III
K8Z33_17255	COG1982	Orn Lys Arg decarboxylase major
K8Z33_17300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z33_17310	COG0590	tRNA wobble adenosine to inosine editing
K8Z33_17315	COG1335	isochorismatase
K8Z33_17320	COG1428	Deoxynucleoside kinase
K8Z33_17325	COG1428	Deoxynucleoside kinase
K8Z33_17355	COG1686	Belongs to the peptidase S11 family
K8Z33_17360	COG0516	GMP reductase activity
K8Z33_17360	COG0517	IMP dehydrogenase activity
K8Z33_17395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z33_17400	COG0187	DNA topoisomerase II activity
K8Z33_17410	COG2501	S4 domain
K8Z33_17415	COG0592	DNA-directed DNA polymerase activity
K8Z33_17425	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z33_17440	COG1847	R3H domain protein
K8Z33_17465	COG1192	Involved in chromosome partitioning
K8Z33_17470	COG1475	DNA binding
K8Z33_17480	COG0668	transmembrane transport
K8Z33_17485	COG4481	Protein conserved in bacteria
K8Z33_17490	COG0012	GTP binding
K8Z33_17500	COG0629	single-stranded DNA binding
K8Z33_17510	COG4241	membrane
K8Z33_17515	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z33_17525	COG0305	Participates in initiation and elongation during chromosome replication
K8Z33_17555	COG0745	RESPONSE REGULATOR receiver
K8Z33_17560	COG5002	protein histidine kinase activity
K8Z33_17570	COG4853	Protein conserved in bacteria
K8Z33_17575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z33_17580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z33_17595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K8Z33_17645	COG0322	excinuclease ABC activity
K8Z33_17650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z33_17700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z33_17720	COG1164	Oligoendopeptidase f
K8Z33_17740	COG1272	protein, Hemolysin III
K8Z33_17745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z33_17770	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
K8Z33_17775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z33_17780	COG2814	Major facilitator Superfamily
K8Z33_17785	COG3275	phosphorelay sensor kinase activity
K8Z33_17805	COG0628	permease
K8Z33_17810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z33_17810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z33_17815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z33_17820	COG1309	transcriptional regulator
K8Z33_17825	COG0488	(ABC) transporter
K8Z33_17830	COG1309	transcriptional regulator
K8Z33_17840	COG0463	Glycosyl transferase, family 2
K8Z33_17845	COG4485	Bacterial membrane protein, YfhO
K8Z33_17855	COG1216	Glycosyl transferase, family 2
K8Z33_17870	COG1216	Glycosyl transferase, family 2
K8Z33_17875	COG1607	acyl-coa hydrolase
K8Z33_17885	COG0840	transmembrane signaling receptor activity
K8Z33_17900	COG0438	transferase activity, transferring glycosyl groups
K8Z33_17910	COG0477	Major facilitator Superfamily
K8Z33_17915	COG3279	Response regulator of the LytR AlgR family
K8Z33_17920	COG1966	Carbon starvation protein
K8Z33_17925	COG2879	small protein
K8Z33_17930	COG3706	GGDEF domain
K8Z33_17935	COG0351	phosphomethylpyrimidine kinase
K8Z33_17940	COG2203	Gaf domain
K8Z33_17940	COG4585	Histidine kinase
K8Z33_17945	COG2197	response regulator
K8Z33_17955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z33_17960	COG1011	Hydrolase
K8Z33_17965	COG2873	o-acetylhomoserine
K8Z33_17975	COG0460	homoserine dehydrogenase
K8Z33_17985	COG1609	Transcriptional regulator
K8Z33_17990	COG2755	lipolytic protein G-D-S-L family
K8Z33_17995	COG1131	(ABC) transporter
K8Z33_18000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K8Z33_18010	COG2814	Major facilitator Superfamily
K8Z33_18015	COG0561	phosphatase activity
K8Z33_18020	COG2233	PERMEase
K8Z33_18025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z33_18035	COG2363	Small membrane protein
K8Z33_18045	COG3773	Cell wall hydrolase
K8Z33_18060	COG0280	phosphate acetyltransferase
K8Z33_18080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_18085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_18090	COG1120	ATPase activity
K8Z33_18095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z33_18100	COG1078	dGTPase activity
K8Z33_18110	COG1994	Peptidase M50
K8Z33_18120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z33_18125	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z33_18130	COG0789	Transcriptional regulator
K8Z33_18135	COG2814	Major facilitator Superfamily
K8Z33_18160	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z33_18165	COG4506	Protein conserved in bacteria
K8Z33_18175	COG1595	DNA-templated transcription, initiation
K8Z33_18195	COG2234	aminopeptidase activity
K8Z33_18205	COG0024	Methionine aminopeptidase
K8Z33_18210	COG1131	(ABC) transporter
K8Z33_18215	COG0842	Transport permease protein
K8Z33_18220	COG4585	Histidine kinase
K8Z33_18225	COG2197	response regulator
K8Z33_18230	COG3227	Zinc metalloprotease (Elastase)
K8Z33_18245	COG5001	Diguanylate cyclase
K8Z33_18245	COG3300	MHYT domain
K8Z33_18255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z33_18300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K8Z33_18305	COG1404	Belongs to the peptidase S8 family
K8Z33_18345	COG3620	sequence-specific DNA binding
K8Z33_18350	COG0247	lactate metabolic process
K8Z33_18350	COG2181	nitrate reductase activity
K8Z33_18355	COG0183	Belongs to the thiolase family
K8Z33_18360	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z33_18365	COG1960	acyl-CoA dehydrogenase activity
K8Z33_18370	COG1960	acyl-CoA dehydrogenase activity
K8Z33_18390	COG4821	SIS domain
K8Z33_18410	COG1494	fructose-1,6-bisphosphatase
K8Z33_18415	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z33_18450	COG0009	L-threonylcarbamoyladenylate synthase
K8Z33_18470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z33_18475	COG2259	Doxx family
K8Z33_18480	COG2190	(PTS) system
K8Z33_18490	COG0698	ribose 5-phosphate isomerase
K8Z33_18525	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z33_18575	COG3300	MHYT domain
K8Z33_18575	COG5001	Diguanylate cyclase
K8Z33_18590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z33_18610	COG0839	Belongs to the complex I subunit 6 family
K8Z33_18620	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z33_18625	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z33_18630	COG1007	ATP synthesis coupled electron transport
K8Z33_18635	COG4836	Membrane
K8Z33_18650	COG2385	sporulation resulting in formation of a cellular spore
K8Z33_18655	COG3279	Response regulator of the LytR AlgR family
K8Z33_18670	COG0739	heme binding
K8Z33_18680	COG1609	Transcriptional regulator
K8Z33_18695	COG0489	protein tyrosine kinase activity
K8Z33_18700	COG3944	biosynthesis protein
K8Z33_18705	COG0489	protein tyrosine kinase activity
K8Z33_18710	COG4464	protein tyrosine phosphatase activity
K8Z33_18715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z33_18735	COG0438	transferase activity, transferring glycosyl groups
K8Z33_18740	COG1215	transferase activity, transferring glycosyl groups
K8Z33_18745	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z33_18750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z33_18755	COG1316	TRANSCRIPTIONal
K8Z33_18765	COG0745	RESPONSE REGULATOR receiver
K8Z33_18770	COG5002	protein histidine kinase activity
K8Z33_18805	COG1136	(ABC) transporter
K8Z33_18810	COG0577	efflux transmembrane transporter activity
K8Z33_18850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z33_18855	COG4715	Zinc finger, swim domain protein
K8Z33_18880	COG1388	LysM domain
K8Z33_18880	COG3584	3D domain protein
K8Z33_18885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z33_18890	COG1215	transferase activity, transferring glycosyl groups
K8Z33_18900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_18905	COG0791	NLP P60 protein
K8Z33_18905	COG1388	LysM domain
K8Z33_18915	COG1368	sulfuric ester hydrolase activity
K8Z33_18925	COG2389	metal-binding protein
K8Z33_18935	COG1620	l-lactate permease
K8Z33_18945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z33_18950	COG1294	oxidase, subunit
K8Z33_18955	COG1271	oxidase subunit
K8Z33_18970	COG0583	DNA-binding transcription factor activity
K8Z33_18975	COG1511	domain protein
K8Z33_18990	COG1301	dicarboxylic acid transport
K8Z33_18995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z33_19005	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z33_19015	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K8Z33_19025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z33_19030	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z33_19035	COG1486	melibiose metabolic process
K8Z33_19055	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z33_19055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z33_19065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z33_19070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z33_19075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z33_19080	COG1316	TRANSCRIPTIONal
K8Z33_19085	COG1739	Uncharacterized protein family UPF0029
K8Z33_19090	COG1307	EDD domain protein, DegV family
K8Z33_19095	COG1733	regulation of RNA biosynthetic process
K8Z33_19100	COG0791	NLP P60 protein
K8Z33_19100	COG1388	LysM domain
K8Z33_19105	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z33_19110	COG1040	competence protein
K8Z33_19115	COG1278	Cold shock
K8Z33_19120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z33_19140	COG2884	Cell division ATP-binding protein ftsE
K8Z33_19145	COG2177	Part of the ABC transporter FtsEX involved in
K8Z33_19150	COG0793	Belongs to the peptidase S41A family
K8Z33_19150	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_19155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z33_19160	COG1132	(ABC) transporter
K8Z33_19170	COG0488	(ABC) transporter
K8Z33_19175	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z33_19185	COG0583	DNA-binding transcription factor activity
K8Z33_19205	COG0789	Transcriptional regulator
K8Z33_19225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z33_19235	COG1950	PFAM Membrane protein of
K8Z33_19255	COG0110	maltose O-acetyltransferase activity
K8Z33_19260	COG0457	Tetratricopeptide repeat
K8Z33_19265	COG0492	ferredoxin-NADP+ reductase activity
K8Z33_19275	COG1051	belongs to the nudix hydrolase family
K8Z33_19285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z33_19295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z33_19305	COG2323	membrane
K8Z33_19320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z33_19345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z33_19360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z33_19395	COG1346	cytolysis
K8Z33_19400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z33_19405	COG1647	Serine aminopeptidase, S33
K8Z33_19410	COG0557	exoribonuclease II activity
K8Z33_19455	COG2233	PERMEase
K8Z33_19460	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z33_19465	COG0288	reversible hydration of carbon dioxide
K8Z33_19470	COG1522	sequence-specific DNA binding
K8Z33_19480	COG1522	sequence-specific DNA binding
K8Z33_19485	COG1335	isochorismatase
K8Z33_19505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_19510	COG0488	(ABC) transporter
K8Z33_19545	COG0840	transmembrane signaling receptor activity
K8Z33_19545	COG3290	protein histidine kinase activity
K8Z33_19565	COG1252	NADH dehydrogenase
K8Z33_19575	COG1733	regulation of RNA biosynthetic process
K8Z33_19580	COG2814	Major facilitator Superfamily
K8Z33_19585	COG0656	L-ascorbic acid biosynthetic process
K8Z33_19600	COG2910	NAD(P)H-binding
K8Z33_19605	COG1115	amino acid carrier protein
K8Z33_19610	COG1115	amino acid carrier protein
K8Z33_19615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_19620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_19630	COG1528	Iron-storage protein
K8Z33_19640	COG1611	Belongs to the LOG family
K8Z33_19655	COG0783	Belongs to the Dps family
K8Z33_19660	COG1115	amino acid carrier protein
K8Z33_19665	COG0490	domain, Protein
K8Z33_19670	COG0475	glutathione-regulated potassium exporter activity
K8Z33_19675	COG0586	Pfam SNARE associated Golgi protein
K8Z33_19695	COG3227	Zinc metalloprotease (Elastase)
K8Z33_19705	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z33_19710	COG0840	transmembrane signaling receptor activity
K8Z33_19740	COG5002	protein histidine kinase activity
K8Z33_19745	COG0745	RESPONSE REGULATOR receiver
K8Z33_19750	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z33_19760	COG0586	Pfam SNARE associated Golgi protein
K8Z33_19795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_19820	COG0531	amino acid
K8Z33_19825	COG2814	Major facilitator Superfamily
K8Z33_19840	COG0840	transmembrane signaling receptor activity
K8Z33_19845	COG0011	TIGRFAM Protein of
K8Z33_19860	COG1686	Belongs to the peptidase S11 family
K8Z33_19870	COG1024	Enoyl-CoA hydratase
K8Z33_19870	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z33_19875	COG0183	Belongs to the thiolase family
K8Z33_19880	COG1960	acyl-CoA dehydrogenase activity
K8Z33_19885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_19900	COG0039	L-malate dehydrogenase activity
K8Z33_19920	COG1393	Belongs to the ArsC family
K8Z33_19930	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z33_19935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z33_19950	COG2011	ABC-type metal ion transport system permease component
K8Z33_19955	COG1464	Belongs to the NlpA lipoprotein family
K8Z33_19960	COG1464	Belongs to the NlpA lipoprotein family
K8Z33_19965	COG0396	ATPase activity
K8Z33_19970	COG0719	Fe-S assembly protein
K8Z33_19975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z33_19980	COG0822	iron-sulfur transferase activity
K8Z33_19985	COG0719	Fe-S assembly protein
K8Z33_19990	COG0737	Belongs to the 5'-nucleotidase family
K8Z33_19995	COG3377	Domain of unknown function (DUF1805)
K8Z33_20005	COG0739	heme binding
K8Z33_20030	COG4377	Putative membrane peptidase family (DUF2324)
K8Z33_20035	COG0789	Transcriptional regulator
K8Z33_20045	COG4470	Protein conserved in bacteria
K8Z33_20060	COG1494	fructose-1,6-bisphosphatase
K8Z33_20065	COG2445	Protein of unknown function DUF86
K8Z33_20075	COG0647	UMP catabolic process
K8Z33_20080	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z33_20090	COG1358	cellular component organization or biogenesis
K8Z33_20110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z33_20115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z33_20125	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z33_20130	COG4837	Protein of unknown function (DUF1462)
K8Z33_20175	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z33_20180	COG0390	transport system, permease component
K8Z33_20185	COG2274	protein secretion by the type I secretion system
K8Z33_20195	COG1252	NADH dehydrogenase
K8Z33_20210	COG0316	Belongs to the HesB IscA family
K8Z33_20240	COG1683	Conserved Protein
K8Z33_20255	COG3708	Transcriptional regulator
K8Z33_20265	COG1252	NADH dehydrogenase
K8Z33_20280	COG3584	3D domain protein
K8Z33_20295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z33_20300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z33_20305	COG1268	BioY protein
K8Z33_20315	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z33_20335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z33_20340	COG5018	Exonuclease
K8Z33_20360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z33_20370	COG2267	carboxylic ester hydrolase activity
K8Z33_20375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z33_20380	COG1522	sequence-specific DNA binding
K8Z33_20385	COG0436	Aminotransferase
K8Z33_20390	COG1098	S1 RNA binding domain
K8Z33_20395	COG2155	Conserved Protein
K8Z33_20410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z33_20415	COG1285	pathogenesis
K8Z33_20550	COG1309	transcriptional regulator
K8Z33_20575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z33_20580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z33_20590	COG0058	SHG alpha-glucan phosphorylase activity
K8Z33_20615	COG1278	Cold shock
K8Z33_20620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z33_20625	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z33_20630	COG1169	isochorismate synthase
K8Z33_20640	COG0596	Alpha beta hydrolase
K8Z33_20645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z33_20655	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z33_20675	COG3964	amidohydrolase
K8Z33_20695	COG2188	Transcriptional regulator
K8Z33_20710	COG0577	efflux transmembrane transporter activity
K8Z33_20715	COG1136	(ABC) transporter
K8Z33_20720	COG0577	efflux transmembrane transporter activity
K8Z33_20725	COG0577	efflux transmembrane transporter activity
K8Z33_20730	COG2205	protein histidine kinase activity
K8Z33_20735	COG0745	RESPONSE REGULATOR receiver
K8Z33_20745	COG0640	Transcriptional regulator
K8Z33_20750	COG5658	integral membrane protein
K8Z33_20755	COG1131	(ABC) transporter
K8Z33_20765	COG2207	Transcriptional regulator
K8Z33_20765	COG3708	Transcriptional regulator
K8Z33_20770	COG1136	(ABC) transporter
K8Z33_20775	COG0577	efflux transmembrane transporter activity
K8Z33_20785	COG0586	Pfam SNARE associated Golgi protein
K8Z33_20795	COG5002	protein histidine kinase activity
K8Z33_20845	COG1597	lipid kinase activity
K8Z33_20850	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z33_20875	COG0745	RESPONSE REGULATOR receiver
K8Z33_20880	COG5002	protein histidine kinase activity
K8Z33_20885	COG3859	Proton-coupled thiamine transporter YuaJ
K8Z33_20910	COG1842	Phage shock protein A
K8Z33_20935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_20955	COG1294	oxidase, subunit
K8Z33_20960	COG1271	oxidase subunit
K8Z33_20965	COG0288	reversible hydration of carbon dioxide
K8Z33_20975	COG1854	S-ribosylhomocysteine lyase activity
K8Z33_20980	COG0789	Transcriptional regulator
K8Z33_20985	COG2076	Multidrug Resistance protein
K8Z33_20990	COG2076	Multidrug Resistance protein
K8Z33_21020	COG0494	nUDIX hydrolase
K8Z33_21045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z33_21050	COG1116	anion transmembrane transporter activity
K8Z33_21055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z33_21080	COG1368	sulfuric ester hydrolase activity
K8Z33_21085	COG2267	carboxylic ester hydrolase activity
K8Z33_21090	COG0753	catalase activity
K8Z33_21095	COG3852	Histidine kinase
K8Z33_21100	COG5002	protein histidine kinase activity
K8Z33_21195	COG0438	transferase activity, transferring glycosyl groups
K8Z33_21200	COG0671	phosphoesterase, PA-phosphatase related
K8Z33_21205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z33_21210	COG2267	carboxylic ester hydrolase activity
K8Z33_21225	COG1794	racemase activity, acting on amino acids and derivatives
K8Z33_21230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z33_21235	COG1242	4 iron, 4 sulfur cluster binding
K8Z33_21255	COG1136	(ABC) transporter
K8Z33_21265	COG0582	viral genome integration into host DNA
K8Z33_21270	COG0490	domain, Protein
K8Z33_21275	COG0475	glutathione-regulated potassium exporter activity
K8Z33_21280	COG2814	Major facilitator Superfamily
K8Z33_21320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z33_21330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z33_21350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z33_21355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z33_21365	COG0303	'Molybdopterin
K8Z33_21370	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z33_21375	COG0314	molybdopterin synthase activity
K8Z33_21400	COG1329	Transcriptional regulator
K8Z33_21420	COG3832	glyoxalase III activity
K8Z33_21430	COG2814	Major facilitator Superfamily
K8Z33_21435	COG2081	HI0933 family
K8Z33_21440	COG2244	polysaccharide biosynthetic process
K8Z33_21445	COG1187	pseudouridine synthase activity
K8Z33_21450	COG1349	DNA-binding transcription factor activity
K8Z33_21455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z33_21465	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z33_21470	COG0510	thiamine kinase activity
K8Z33_21485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_21495	COG1363	Peptidase, m42
K8Z33_21500	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z33_21505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z33_21515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z33_21530	COG1674	ftsk spoiiie
K8Z33_21545	COG0789	Transcriptional regulator
K8Z33_21550	COG0697	spore germination
K8Z33_21555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_21570	COG2309	aminopeptidase activity
K8Z33_21580	COG3118	belongs to the thioredoxin family
K8Z33_21585	COG4851	CamS sex pheromone cAM373 precursor
K8Z33_21590	COG1605	Chorismate mutase
K8Z33_21590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z33_21595	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z33_21595	COG1605	Chorismate mutase
K8Z33_21605	COG1609	Transcriptional regulator
K8Z33_21640	COG0666	response to abiotic stimulus
K8Z33_21645	COG5002	protein histidine kinase activity
K8Z33_21650	COG0745	RESPONSE REGULATOR receiver
K8Z33_21665	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z33_21670	COG0517	IMP dehydrogenase activity
K8Z33_21675	COG0454	-acetyltransferase
K8Z33_21680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z33_21685	COG0110	maltose O-acetyltransferase activity
K8Z33_21710	COG0626	cystathionine gamma-synthase activity
K8Z33_21715	COG1956	GAF domain-containing protein
K8Z33_21720	COG1309	transcriptional regulator
K8Z33_21725	COG0697	spore germination
K8Z33_21730	COG0583	DNA-binding transcription factor activity
K8Z33_21740	COG1104	cysteine desulfurase activity
K8Z33_21755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z33_21765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z33_21780	COG3874	Sporulation protein YtfJ
K8Z33_21785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z33_21790	COG0827	DNA restriction-modification system
K8Z33_21815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_21860	COG0589	response to stress
K8Z33_21865	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_21880	COG0662	Cupin 2, conserved barrel domain protein
K8Z33_21885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_21920	COG0006	proline dipeptidase activity
K8Z33_21935	COG4109	DRTGG domain
K8Z33_21950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z33_21965	COG0587	DNA-directed DNA polymerase activity
K8Z33_21970	COG0281	malic enzyme
K8Z33_21975	COG1725	Transcriptional regulator
K8Z33_22000	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z33_22005	COG0628	permease
K8Z33_22015	COG0372	Belongs to the citrate synthase family
K8Z33_22020	COG0538	isocitrate dehydrogenase activity
K8Z33_22040	COG0745	RESPONSE REGULATOR receiver
K8Z33_22045	COG5002	protein histidine kinase activity
K8Z33_22050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z33_22050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z33_22060	COG1971	Probably functions as a manganese efflux pump
K8Z33_22065	COG0237	dephospho-CoA kinase activity
K8Z33_22070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z33_22075	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z33_22085	COG3611	Membrane attachment protein
K8Z33_22090	COG1484	DNA-dependent DNA replication
K8Z33_22105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z33_22130	COG1363	Peptidase, m42
K8Z33_22135	COG1309	transcriptional regulator
K8Z33_22140	COG1566	PFAM secretion protein HlyD family protein
K8Z33_22145	COG2814	Major facilitator Superfamily
K8Z33_22160	COG1418	mRNA catabolic process
K8Z33_22170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z33_22210	COG1286	toxin biosynthetic process
K8Z33_22215	COG1796	DNA polymerase
K8Z33_22215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z33_22225	COG1187	pseudouridine synthase activity
K8Z33_22230	COG1114	Component of the transport system for branched-chain amino acids
K8Z33_22235	COG5386	Cell surface protein
K8Z33_22245	COG5386	Cell surface protein
K8Z33_22260	COG1120	ATPase activity
K8Z33_22265	COG4509	Sortase family
K8Z33_22275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z33_22280	COG4895	conserved protein (DUF2196)
K8Z33_22290	COG0745	RESPONSE REGULATOR receiver
K8Z33_22295	COG2205	protein histidine kinase activity
K8Z33_22300	COG1131	(ABC) transporter
K8Z33_22320	COG2318	DinB family
K8Z33_22345	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_22350	COG1309	transcriptional regulator
K8Z33_22355	COG1024	Enoyl-CoA hydratase
K8Z33_22360	COG2086	electron transfer activity
K8Z33_22365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z33_22370	COG3118	belongs to the thioredoxin family
K8Z33_22380	COG1719	4-vinyl reductase, 4VR
K8Z33_22385	COG2009	succinate dehydrogenase
K8Z33_22390	COG1053	succinate dehydrogenase
K8Z33_22395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z33_22400	COG0824	Thioesterase
K8Z33_22405	COG1876	peptidase activity
K8Z33_22410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z33_22415	COG1360	Flagellar Motor Protein
K8Z33_22420	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z33_22425	COG4152	abc transporter atp-binding protein
K8Z33_22430	COG1668	transmembrane transport
K8Z33_22435	COG1959	2 iron, 2 sulfur cluster binding
K8Z33_22445	COG0697	spore germination
K8Z33_22450	COG1396	sequence-specific DNA binding
K8Z33_22455	COG1983	PspC domain protein
K8Z33_22460	COG0402	S-adenosylhomocysteine deaminase activity
K8Z33_22465	COG2233	PERMEase
K8Z33_22470	COG2197	response regulator
K8Z33_22480	COG1309	transcriptional regulator
K8Z33_22500	COG5401	PFAM Sporulation and spore germination
K8Z33_22515	COG0622	Phosphoesterase
K8Z33_22565	COG0470	DNA polymerase III
K8Z33_22565	COG1067	ATP-dependent peptidase activity
K8Z33_22580	COG1764	response to oxidative stress
K8Z33_22585	COG1846	Transcriptional regulator
K8Z33_22595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z33_22605	COG1587	Uroporphyrinogen-III synthase
K8Z33_22610	COG0113	porphobilinogen synthase activity
K8Z33_22620	COG1388	LysM domain
K8Z33_22635	COG0285	dihydrofolate synthase activity
K8Z33_22655	COG1077	Cell shape determining protein MreB Mrl
K8Z33_22675	COG2894	cell division
K8Z33_22680	COG0739	heme binding
K8Z33_22685	COG1994	Peptidase M50
K8Z33_22690	COG1530	ribonuclease E activity
K8Z33_22700	COG2868	ribosomal protein
K8Z33_22710	COG3290	protein histidine kinase activity
K8Z33_22720	COG0745	RESPONSE REGULATOR receiver
K8Z33_22725	COG5002	protein histidine kinase activity
K8Z33_22730	COG1136	(ABC) transporter
K8Z33_22735	COG0577	efflux transmembrane transporter activity
K8Z33_22740	COG0577	efflux transmembrane transporter activity
K8Z33_22745	COG0077	Prephenate dehydratase
K8Z33_22755	COG2258	MOSC domain
K8Z33_22760	COG1827	regulation of RNA biosynthetic process
K8Z33_22765	COG1104	cysteine desulfurase activity
K8Z33_22770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z33_22775	COG0157	Belongs to the NadC ModD family
K8Z33_22805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z33_22835	COG1862	Preprotein translocase
K8Z33_22845	COG2323	membrane
K8Z33_22850	COG2244	polysaccharide biosynthetic process
K8Z33_22860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z33_22860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z33_22865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z33_22870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z33_22870	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z33_22880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z33_22910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z33_22920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z33_22925	COG1959	2 iron, 2 sulfur cluster binding
K8Z33_22930	COG1104	cysteine desulfurase activity
K8Z33_22945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z33_22965	COG0628	permease
K8Z33_22980	COG4472	Bacterial protein of unknown function (DUF965)
K8Z33_22995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z33_23000	COG4122	O-methyltransferase activity
K8Z33_23005	COG0826	peptidase U32
K8Z33_23010	COG0826	peptidase U32
K8Z33_23030	COG0768	penicillin binding
K8Z33_23055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z33_23060	COG0626	cystathionine gamma-synthase activity
K8Z33_23065	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_23065	COG1454	alcohol dehydrogenase
K8Z33_23075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z33_23115	COG2259	Doxx family
K8Z33_23120	COG2514	catechol 2,3-dioxygenase activity
K8Z33_23130	COG3186	Phenylalanine-4-hydroxylase
K8Z33_23135	COG1404	Belongs to the peptidase S8 family
K8Z33_23170	COG2267	carboxylic ester hydrolase activity
K8Z33_23180	COG1785	Belongs to the alkaline phosphatase family
K8Z33_23190	COG2357	RelA SpoT domain protein
K8Z33_23195	COG0778	Nitroreductase
K8Z33_23205	COG1595	DNA-templated transcription, initiation
K8Z33_23230	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z33_23235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z33_23245	COG1534	Rna-binding protein
K8Z33_23255	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z33_23260	COG0799	negative regulation of ribosome biogenesis
K8Z33_23265	COG2226	methyltransferase
K8Z33_23270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z33_23275	COG1555	photosystem II stabilization
K8Z33_23275	COG1596	polysaccharide export
K8Z33_23280	COG2131	deaminase
K8Z33_23285	COG0658	competence protein
K8Z33_23285	COG2333	competence protein COMEC
K8Z33_23295	COG1466	dna polymerase III delta subunit
K8Z33_23320	COG1733	regulation of RNA biosynthetic process
K8Z33_23325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z33_23355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z33_23360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z33_23365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z33_23370	COG1610	YqeY-like protein
K8Z33_23390	COG1702	phosphate starvation-inducible protein PhoH
K8Z33_23395	COG1480	7TM receptor with intracellular HD hydrolase
K8Z33_23405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z33_23410	COG0295	cytidine deaminase activity
K8Z33_23415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z33_23430	COG0517	IMP dehydrogenase activity
K8Z33_23440	COG1671	Belongs to the UPF0178 family
K8Z33_23445	COG0358	DNA primase activity
K8Z33_23450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z33_23460	COG2384	SAM-dependent methyltransferase
K8Z33_23465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z33_23495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_23500	COG1121	(ABC) transporter
K8Z33_23505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z33_23510	COG0735	belongs to the Fur family
K8Z33_23525	COG5521	maltodextrose utilization protein MalA
K8Z33_23535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z33_23540	COG0477	Major facilitator Superfamily
K8Z33_23545	COG0582	viral genome integration into host DNA
K8Z33_23570	COG1396	sequence-specific DNA binding
K8Z33_23650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z33_23745	COG1388	LysM domain
K8Z33_23745	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_23745	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_23785	COG0768	penicillin binding
K8Z33_23795	COG0573	inorganic phosphate transmembrane transporter activity
K8Z33_23800	COG0573	inorganic phosphate transmembrane transporter activity
K8Z33_23810	COG0704	Plays a role in the regulation of phosphate uptake
K8Z33_23815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z33_23820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z33_23825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z33_23830	COG4483	Protein conserved in bacteria
K8Z33_23835	COG1940	carbohydrate kinase activity
K8Z33_23845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_23865	COG0626	cystathionine gamma-synthase activity
K8Z33_23870	COG0626	cystathionine gamma-synthase activity
K8Z33_23875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z33_23875	COG0646	methionine synthase
K8Z33_23880	COG1410	methionine synthase
K8Z33_23880	COG0646	methionine synthase
K8Z33_23935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z33_23940	COG1459	type II secretion system
K8Z33_23975	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K8Z33_24005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z33_24045	COG2076	Multidrug Resistance protein
K8Z33_24050	COG2076	Multidrug Resistance protein
K8Z33_24060	COG1609	Transcriptional regulator
K8Z33_24070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z33_24105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z33_24115	COG3872	metal-dependent enzyme
K8Z33_24130	COG0006	proline dipeptidase activity
K8Z33_24155	COG3854	ATPases associated with a variety of cellular activities
K8Z33_24200	COG0511	ligase activity, forming carbon-carbon bonds
K8Z33_24205	COG0439	Biotin carboxylase
K8Z33_24210	COG1302	Protein conserved in bacteria
K8Z33_24235	COG0142	geranyltranstransferase activity
K8Z33_24245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z33_24255	COG0497	DNA recombination
K8Z33_24260	COG0750	zinc metalloprotease
K8Z33_24300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z33_24345	COG3093	addiction module antidote protein HigA
K8Z33_24350	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z33_24360	COG3290	protein histidine kinase activity
K8Z33_24360	COG3829	transcription factor binding
K8Z33_24365	COG0280	phosphate acetyltransferase
K8Z33_24380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z33_24385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z33_24390	COG0022	dehydrogenase e1 component
K8Z33_24395	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z33_24400	COG0772	Belongs to the SEDS family
K8Z33_24405	COG2323	membrane
K8Z33_24425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z33_24430	COG0765	amino acid transport
K8Z33_24435	COG1126	abc transporter atp-binding protein
K8Z33_24440	COG4129	membrane
K8Z33_24445	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z33_24460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z33_24465	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z33_24480	COG1285	pathogenesis
K8Z33_24510	COG1760	l-serine dehydratase
K8Z33_24515	COG1760	l-serine dehydratase
K8Z33_24520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z33_24525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z33_24530	COG0300	oxidoreductase activity
K8Z33_24575	COG1522	sequence-specific DNA binding
K8Z33_24585	COG0737	Belongs to the 5'-nucleotidase family
K8Z33_24590	COG1757	Na H antiporter
K8Z33_24600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z33_24615	COG1073	alpha beta
K8Z33_24615	COG2226	methyltransferase
K8Z33_24645	COG0307	riboflavin synthase, alpha
K8Z33_24650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z33_24650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z33_24665	COG1073	alpha beta
K8Z33_24670	COG0456	acetyltransferase
K8Z33_24675	COG1609	Transcriptional regulator
K8Z33_24680	COG2056	Na+-H+ antiporter family
K8Z33_24685	COG0596	Alpha beta hydrolase
K8Z33_24695	COG0737	Belongs to the 5'-nucleotidase family
K8Z33_24695	COG1525	nuclease
K8Z33_24695	COG4085	toxin activity
K8Z33_24705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z33_24705	COG0456	acetyltransferase
K8Z33_24710	COG0656	L-ascorbic acid biosynthetic process
K8Z33_24715	COG0667	Aldo Keto reductase
K8Z33_24735	COG1300	Membrane
K8Z33_24740	COG0735	belongs to the Fur family
K8Z33_24750	COG4974	Belongs to the 'phage' integrase family
K8Z33_24775	COG0598	Magnesium transport protein CorA
K8Z33_24790	COG1846	Transcriptional regulator
K8Z33_24810	COG1131	(ABC) transporter
K8Z33_24815	COG1725	Transcriptional regulator
K8Z33_24820	COG1686	Belongs to the peptidase S11 family
K8Z33_24840	COG0733	neurotransmitter:sodium symporter activity
K8Z33_24865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z33_24880	COG0697	spore germination
K8Z33_24885	COG0561	phosphatase activity
K8Z33_24890	COG4086	secreted protein
K8Z33_24895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z33_24900	COG0456	acetyltransferase
K8Z33_24905	COG1547	Domain of unknown function (DUF309)
K8Z33_24930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z33_24940	COG2188	Transcriptional regulator
K8Z33_24950	COG3711	transcriptional antiterminator
K8Z33_24955	COG2190	(PTS) system
K8Z33_24955	COG1263	PTS System
K8Z33_24955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z33_24980	COG0778	Nitroreductase
K8Z33_24985	COG2199	diguanylate cyclase activity
K8Z33_24995	COG2084	Dehydrogenase
K8Z33_25030	COG0436	Aminotransferase
K8Z33_25035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z33_25055	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_25060	COG1695	Transcriptional regulator
K8Z33_25095	COG0183	Belongs to the thiolase family
K8Z33_25135	COG3842	ATPase activity
K8Z33_25140	COG0366	Alpha amylase catalytic
K8Z33_25150	COG2182	Extracellular solute-binding protein
K8Z33_25155	COG1175	transmembrane transport
K8Z33_25160	COG3833	ABC-type maltose transport systems, permease component
K8Z33_25165	COG1609	Transcriptional regulator
K8Z33_25170	COG0436	Aminotransferase
K8Z33_25180	COG2205	protein histidine kinase activity
K8Z33_25190	COG3209	COG3209 Rhs family protein
K8Z33_25210	COG2814	Major facilitator Superfamily
K8Z33_25255	COG1408	metallophosphoesterase
K8Z33_25260	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_25265	COG2200	EAL domain
K8Z33_25280	COG4703	Protein of unknown function (DUF1797)
K8Z33_25290	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z33_25300	COG0517	IMP dehydrogenase activity
K8Z33_25305	COG0583	DNA-binding transcription factor activity
K8Z33_25325	COG0569	domain protein
K8Z33_25330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z33_25340	COG0561	phosphatase activity
K8Z33_25355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z33_25360	COG0022	dehydrogenase e1 component
K8Z33_25410	COG1982	Orn Lys Arg decarboxylase major
K8Z33_25430	COG0483	inositol monophosphate 1-phosphatase activity
K8Z33_25440	COG1217	gtp-binding protein TYPA
K8Z33_25455	COG4896	Protein conserved in bacteria
K8Z33_25465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z33_25470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z33_25480	COG0772	Belongs to the SEDS family
K8Z33_25485	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z33_25520	COG3336	cytochrome c oxidase
K8Z33_25535	COG2340	Cysteine-rich secretory protein family
K8Z33_25550	COG0406	alpha-ribazole phosphatase activity
K8Z33_25555	COG3679	Belongs to the UPF0342 family
K8Z33_25570	COG0742	ribosomal rna small subunit methyltransferase
K8Z33_25580	COG3314	Sporulation integral membrane protein YlbJ
K8Z33_25585	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z33_25590	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z33_25600	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z33_25605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z33_25620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z33_25640	COG0768	penicillin binding
K8Z33_25645	COG0768	penicillin binding
K8Z33_25665	COG0772	Belongs to the SEDS family
K8Z33_25685	COG0849	cell division
K8Z33_25690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z33_25700	COG1191	sigma factor activity
K8Z33_25705	COG1191	sigma factor activity
K8Z33_25710	COG1873	PFAM PRC-barrel domain
K8Z33_25720	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z33_25730	COG0762	integral membrane protein
K8Z33_25735	COG2302	S4 RNA-binding domain
K8Z33_25740	COG3599	regulation of cell shape
K8Z33_25760	COG0564	pseudouridine synthase activity
K8Z33_25820	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z33_25840	COG0006	proline dipeptidase activity
K8Z33_25850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z33_25855	COG1561	YicC-like family, N-terminal region
K8Z33_25875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z33_25880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z33_25895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z33_25895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z33_25905	COG0631	protein serine/threonine phosphatase activity
K8Z33_25910	COG2815	serine threonine protein kinase
K8Z33_25910	COG0515	serine threonine protein kinase
K8Z33_25920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z33_25925	COG1564	THIamine pyrophosphokinase
K8Z33_25940	COG1302	Protein conserved in bacteria
K8Z33_25945	COG1461	Dihydroxyacetone kinase
K8Z33_25950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z33_25965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z33_25970	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_25975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z33_25985	COG1196	nuclear chromosome segregation
K8Z33_25990	COG0552	protein localization to endoplasmic reticulum
K8Z33_26000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z33_26010	COG1837	Belongs to the UPF0109 family
K8Z33_26050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z33_26055	COG0758	DNA mediated transformation
K8Z33_26060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z33_26070	COG4974	Belongs to the 'phage' integrase family
K8Z33_26115	COG4589	Belongs to the CDS family
K8Z33_26125	COG0750	zinc metalloprotease
K8Z33_26145	COG0195	Participates in both transcription termination and antitermination
K8Z33_26150	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z33_26155	COG1358	cellular component organization or biogenesis
K8Z33_26165	COG1550	Protein conserved in bacteria
K8Z33_26170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z33_26180	COG0196	riboflavin kinase activity
K8Z33_26195	COG0726	polysaccharide deacetylase
K8Z33_26200	COG0612	Peptidase, M16
K8Z33_26205	COG1873	PFAM PRC-barrel domain
K8Z33_26210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z33_26235	COG1396	sequence-specific DNA binding
K8Z33_26280	COG0305	Participates in initiation and elongation during chromosome replication
K8Z33_26315	COG0582	viral genome integration into host DNA
K8Z33_26320	COG1278	Cold shock
K8Z33_26325	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z33_26445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z33_26450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z33_26455	COG0527	aspartate kinase activity
K8Z33_26465	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z33_26470	COG0740	serine-type endopeptidase activity
K8Z33_26485	COG2188	Transcriptional regulator
K8Z33_26490	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z33_26495	COG3845	ABC transporter
K8Z33_26500	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z33_26505	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z33_26510	COG0612	Peptidase, M16
K8Z33_26515	COG0612	Peptidase, M16
K8Z33_26520	COG0300	oxidoreductase activity
K8Z33_26535	COG1426	Protein conserved in bacteria
K8Z33_26540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z33_26560	COG1692	metallophosphoesterase
K8Z33_26565	COG2359	stage V sporulation protein S
K8Z33_26575	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z33_26575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z33_26580	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z33_26590	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z33_26615	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z33_26620	COG1368	sulfuric ester hydrolase activity
K8Z33_26630	COG3773	Cell wall hydrolase
K8Z33_26635	COG1404	Belongs to the peptidase S8 family
K8Z33_26645	COG0840	transmembrane signaling receptor activity
K8Z33_26655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_26665	COG1346	cytolysis
K8Z33_26700	COG5001	Diguanylate cyclase
K8Z33_26700	COG3300	MHYT domain
K8Z33_26705	COG2267	carboxylic ester hydrolase activity
K8Z33_26720	COG2364	Membrane
K8Z33_26730	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z33_26735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z33_26740	COG2169	Transcriptional regulator
K8Z33_26745	COG0708	Exodeoxyribonuclease III
K8Z33_26750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z33_26755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_26760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z33_26765	COG1120	ATPase activity
K8Z33_26770	COG2819	hydrolase of the alpha beta superfamily
K8Z33_26790	COG1937	Protein conserved in bacteria
K8Z33_26795	COG2608	mercury ion transmembrane transporter activity
K8Z33_26800	COG2217	Heavy metal translocating P-type atpase
K8Z33_26815	COG2116	formate transmembrane transporter activity
K8Z33_26820	COG1408	metallophosphoesterase
K8Z33_26835	COG1113	amino acid transport
K8Z33_26845	COG2322	membrane
K8Z33_26850	COG1979	alcohol dehydrogenase
K8Z33_26855	COG1349	DNA-binding transcription factor activity
K8Z33_26860	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z33_26865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z33_26865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z33_26865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z33_26870	COG3584	3D domain protein
K8Z33_26870	COG1388	LysM domain
K8Z33_26915	COG0464	growth
K8Z33_26925	COG2860	membrane
K8Z33_26930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z33_26935	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z33_26940	COG0789	Transcriptional regulator
K8Z33_26945	COG0174	glutamine synthetase
K8Z33_26950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z33_26985	COG0741	lytic transglycosylase activity
K8Z33_26990	COG0739	heme binding
K8Z33_26990	COG0741	lytic transglycosylase activity
K8Z33_26990	COG1196	nuclear chromosome segregation
K8Z33_27000	COG1695	Transcriptional regulator
K8Z33_27020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z33_27030	COG0737	Belongs to the 5'-nucleotidase family
K8Z33_27035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z33_27070	COG1132	(ABC) transporter
K8Z33_27075	COG1132	(ABC) transporter
K8Z33_27100	COG0730	response to heat
K8Z33_27115	COG1346	cytolysis
K8Z33_27125	COG0583	DNA-binding transcription factor activity
K8Z33_27145	COG1131	(ABC) transporter
K8Z33_27155	COG1473	amidohydrolase
K8Z33_27165	COG0785	Cytochrome C biogenesis protein
K8Z33_27170	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z33_27220	COG0010	Belongs to the arginase family
K8Z33_27225	COG1329	Transcriptional regulator
K8Z33_27230	COG1902	pentaerythritol trinitrate reductase activity
K8Z33_27235	COG0069	glutamate synthase activity
K8Z33_27245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z33_27250	COG0346	lactoylglutathione lyase activity
K8Z33_27255	COG0400	carboxylic ester hydrolase activity
K8Z33_27260	COG5002	protein histidine kinase activity
K8Z33_27270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z33_27305	COG1396	sequence-specific DNA binding
K8Z33_27310	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_27315	COG1268	BioY protein
K8Z33_27320	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_27325	COG0183	Belongs to the thiolase family
K8Z33_27340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z33_27350	COG2211	Major facilitator Superfamily
K8Z33_27380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z33_27385	COG1122	ATPase activity
K8Z33_27395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z33_27420	COG0824	Thioesterase
K8Z33_27425	COG4841	protein insertion into membrane
K8Z33_27445	COG0745	RESPONSE REGULATOR receiver
K8Z33_27450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z33_27455	COG1832	CoA-binding protein
K8Z33_27460	COG0187	DNA topoisomerase II activity
K8Z33_27465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z33_27470	COG0673	inositol 2-dehydrogenase activity
K8Z33_27490	COG1131	(ABC) transporter
K8Z33_27500	COG1595	DNA-templated transcription, initiation
K8Z33_27510	COG1316	TRANSCRIPTIONal
K8Z33_27515	COG1301	dicarboxylic acid transport
K8Z33_27520	COG4166	transmembrane transport
K8Z33_27530	COG4166	transmembrane transport
K8Z33_27535	COG4166	transmembrane transport
K8Z33_27540	COG2226	methyltransferase
K8Z33_27590	COG3383	formate dehydrogenase (NAD+) activity
K8Z33_27650	COG5377	YqaJ viral recombinase family
K8Z33_27655	COG3723	Recombinational DNA repair protein, rece pathway
K8Z33_27665	COG1484	DNA-dependent DNA replication
K8Z33_27710	COG3617	BRO family, N-terminal domain
K8Z33_27735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z33_27835	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_27835	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_27835	COG1388	LysM domain
K8Z33_27880	COG2427	Protein of unknown function (DUF1641)
K8Z33_27885	COG5609	conserved protein (DUF2294)
K8Z33_27890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z33_27900	COG2116	formate transmembrane transporter activity
K8Z33_27905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z33_27910	COG0303	'Molybdopterin
K8Z33_27915	COG0314	molybdopterin synthase activity
K8Z33_27925	COG0489	protein tyrosine kinase activity
K8Z33_27940	COG3326	Membrane
K8Z33_27945	COG2962	Rard protein
K8Z33_27950	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z33_27955	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z33_27965	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_27970	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_27980	COG4145	pantothenate transmembrane transporter activity
K8Z33_27995	COG0165	Argininosuccinate lyase
K8Z33_28005	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_28025	COG1051	belongs to the nudix hydrolase family
K8Z33_28035	COG0716	FMN binding
K8Z33_28075	COG2720	vancomycin resistance protein
K8Z33_28080	COG2514	catechol 2,3-dioxygenase activity
K8Z33_28090	COG1285	pathogenesis
K8Z33_28100	COG3852	Histidine kinase
K8Z33_28125	COG1876	peptidase activity
K8Z33_28165	COG1396	sequence-specific DNA binding
K8Z33_28280	COG0582	viral genome integration into host DNA
K8Z33_28410	COG3883	PFAM NLP P60 protein
K8Z33_28410	COG0791	NLP P60 protein
K8Z33_28530	COG1349	DNA-binding transcription factor activity
K8Z33_28560	COG0561	phosphatase activity
K8Z33_28565	COG1725	Transcriptional regulator
K8Z33_28570	COG1131	(ABC) transporter
K8Z33_28605	COG1309	transcriptional regulator
K8Z33_28610	COG2814	Major facilitator Superfamily
K8Z33_28615	COG4122	O-methyltransferase activity
K8Z33_28620	COG0583	DNA-binding transcription factor activity
K8Z33_28645	COG1329	Transcriptional regulator
K8Z33_28660	COG1278	Cold shock
K8Z33_28670	COG1136	(ABC) transporter
K8Z33_28675	COG0577	efflux transmembrane transporter activity
K8Z33_28685	COG0741	lytic transglycosylase activity
K8Z33_28690	COG0772	Belongs to the SEDS family
K8Z33_28720	COG1595	DNA-templated transcription, initiation
K8Z33_28730	COG0768	penicillin binding
K8Z33_28740	COG0546	phosphoglycolate phosphatase activity
K8Z33_28745	COG1349	DNA-binding transcription factor activity
K8Z33_28750	COG0577	efflux transmembrane transporter activity
K8Z33_28755	COG1136	(ABC) transporter
K8Z33_28855	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_28860	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z33_28870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z33_28875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z33_28880	COG0824	Thioesterase
K8Z33_28895	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_28900	COG0367	asparagine synthase
K8Z33_28930	COG2890	protein-(glutamine-N5) methyltransferase activity
K8Z33_28990	COG2732	(Barnase) inhibitor
K8Z33_29020	COG3754	Rhamnan synthesis protein F
K8Z33_29025	COG1131	(ABC) transporter
K8Z33_29030	COG0842	Transport permease protein
K8Z33_29045	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z33_29055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z33_29070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K8Z33_29075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z33_29095	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z33_29130	COG2124	cytochrome p450
K8Z33_29135	COG1846	Transcriptional regulator
K8Z33_29140	COG1846	Transcriptional regulator
K8Z33_29145	COG2814	Major facilitator Superfamily
K8Z33_29155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z33_29160	COG0772	Belongs to the SEDS family
K8Z33_29165	COG2239	Acts as a magnesium transporter
K8Z33_29175	COG4974	Belongs to the 'phage' integrase family
K8Z33_29235	COG0667	Aldo Keto reductase
K8Z33_29255	COG2801	Transposase and inactivated derivatives
K8Z33_29265	COG3048	D-serine ammonia-lyase activity
K8Z33_29270	COG1396	sequence-specific DNA binding
K8Z33_29280	COG2040	homocysteine
K8Z33_29285	COG0833	amino acid
K8Z33_29295	COG0577	efflux transmembrane transporter activity
K8Z33_29300	COG1136	(ABC) transporter
K8Z33_29310	COG0745	RESPONSE REGULATOR receiver
K8Z33_29315	COG3850	Histidine kinase
K8Z33_29315	COG5002	protein histidine kinase activity
K8Z33_29320	COG1482	cell wall glycoprotein biosynthetic process
K8Z33_29325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z33_29325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z33_29325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z33_29330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z33_29330	COG3711	transcriptional antiterminator
K8Z33_29340	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z33_29350	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z33_29350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z33_29400	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z33_29420	COG0659	secondary active sulfate transmembrane transporter activity
K8Z33_29435	COG1476	TRANSCRIPTIONal
K8Z33_29470	COG3011	Protein conserved in bacteria
K8Z33_29490	COG0756	dUTP diphosphatase activity
K8Z33_29520	COG3048	D-serine ammonia-lyase activity
K8Z33_29525	COG1396	sequence-specific DNA binding
K8Z33_29535	COG1876	peptidase activity
K8Z33_29540	COG2843	Capsule synthesis protein
K8Z33_29565	COG2329	Antibiotic biosynthesis monooxygenase
K8Z33_29570	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_29570	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_29580	COG3716	PTS system mannose fructose sorbose family IID component
K8Z33_29585	COG3715	PTS system
K8Z33_29595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z33_29600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z33_29610	COG2376	Dihydroxyacetone kinase
K8Z33_29630	COG3979	chitinase
K8Z33_29650	COG0823	Involved in the tonB-independent uptake of proteins
K8Z33_29675	COG1136	(ABC) transporter
K8Z33_29680	COG0577	efflux transmembrane transporter activity
K8Z33_29685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z33_29695	COG0745	RESPONSE REGULATOR receiver
K8Z33_29700	COG5002	protein histidine kinase activity
K8Z33_29710	COG2070	2-Nitropropane dioxygenase
K8Z33_29740	COG1404	Belongs to the peptidase S8 family
K8Z33_29755	COG0657	acetylesterase activity
K8Z33_29760	COG0531	amino acid
K8Z33_29775	COG0531	amino acid
K8Z33_29790	COG2116	formate transmembrane transporter activity
K8Z33_29795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z33_29800	COG4990	cell redox homeostasis
K8Z33_29815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z33_29820	COG1773	rubredoxin
K8Z33_29825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z33_29830	COG0426	domain, Protein
K8Z33_29845	COG1328	CTP reductase activity
K8Z33_29845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K8Z33_29855	COG0535	radical SAM domain protein
K8Z33_29865	COG1012	belongs to the aldehyde dehydrogenase family
K8Z33_29865	COG1454	alcohol dehydrogenase
K8Z33_29935	COG0515	serine threonine protein kinase
K8Z33_29935	COG2815	serine threonine protein kinase
K8Z33_30355	COG0484	heat shock protein binding
K8Z33_30460	COG0210	DNA helicase
K8Z33_30735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z33_30735	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z33_30755	COG3764	Sortase (surface protein transpeptidase)
K8Z33_30885	COG4990	cell redox homeostasis
K8Z33_31025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z33_31295	COG0187	DNA topoisomerase II activity
K8Z33_31300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z33_31370	COG0358	DNA primase activity
K8Z33_31580	COG1876	peptidase activity
K8Z33_31745	COG4193	domain, Protein
K8Z33_31745	COG5263	repeat protein
K8Z33_31880	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_31880	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_31885	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_31885	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_32035	COG3091	SprT-like family
K8Z33_32120	COG3481	metal-dependent phosphohydrolase, HD sub domain
K8Z33_32195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K8Z33_32320	COG1428	Deoxynucleoside kinase
K8Z33_32340	COG5002	protein histidine kinase activity
K8Z33_32345	COG5002	protein histidine kinase activity
K8Z33_32360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z33_32365	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K8Z33_32410	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K8Z33_32415	COG0756	dUTP diphosphatase activity
K8Z33_32440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z33_32445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K8Z33_32480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K8Z33_32490	COG0629	single-stranded DNA binding
K8Z33_32605	COG3409	Peptidoglycan-binding domain 1 protein
K8Z33_32605	COG1388	LysM domain
K8Z33_32605	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z33_32665	COG0457	Tetratricopeptide repeat
K8Z33_32710	COG4474	Belongs to the UPF0398 family
K8Z33_32820	COG1393	Belongs to the ArsC family
K8Z33_32845	COG2088	sporulation resulting in formation of a cellular spore
K8Z33_32875	COG0617	tRNA 3'-terminal CCA addition
K8Z33_33380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z33_33385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z33_33390	COG1780	Probably involved in ribonucleotide reductase function
K8Z33_33395	COG4974	Belongs to the 'phage' integrase family
K8Z33_33415	COG1404	Belongs to the peptidase S8 family
K8Z33_33420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z33_33430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K8Z33_33440	COG0861	Integral membrane protein TerC family
K8Z33_33450	COG2310	stress, protein
K8Z33_33455	COG2310	stress, protein
K8Z33_33480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K8Z33_33605	COG2002	toxin-antitoxin pair type II binding
K8Z33_33635	COG3842	ATPase activity
K8Z33_33660	COG1136	(ABC) transporter
K8Z33_33665	COG0577	efflux transmembrane transporter activity
K8Z33_33890	COG0697	spore germination
K8Z33_33920	COG1923	regulation of RNA biosynthetic process
K8Z33_33925	COG2002	toxin-antitoxin pair type II binding
K8Z33_33940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z33_33945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z33_33950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z33_33960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z33_34015	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z33_34480	COG0583	DNA-binding transcription factor activity
K8Z33_34485	COG2070	2-Nitropropane dioxygenase
K8Z33_34515	COG3209	COG3209 Rhs family protein
K8Z33_34520	COG1696	Membrane protein involved in D-alanine export
K8Z33_34560	COG4644	lycopene metabolic process
K8Z33_34575	COG1695	Transcriptional regulator
K8Z33_34580	COG1132	(ABC) transporter
K8Z33_34600	COG3620	sequence-specific DNA binding
K8Z33_34705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair