locus-tag	class	description
FM050_00045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FM050_00045	COG0551	DNA topoisomerase type I activity
FM050_00095	COG0457	Tetratricopeptide repeat
FM050_00100	COG4166	transmembrane transport
FM050_00350	COG3344	reverse transcriptase
FM050_00355	COG0791	NLP P60 protein
FM050_00355	COG0741	lytic transglycosylase activity
FM050_00555	COG3344	reverse transcriptase
FM050_00620	COG1923	regulation of RNA biosynthetic process
FM050_00630	COG0457	Tetratricopeptide repeat
FM050_00815	COG0791	NLP P60 protein
FM050_00815	COG0741	lytic transglycosylase activity
FM050_00850	COG3344	reverse transcriptase
FM050_01075	COG3344	reverse transcriptase
FM050_01085	COG3344	reverse transcriptase
FM050_01120	COG4712	double-strand break repair protein
FM050_01125	COG0592	DNA-directed DNA polymerase activity
FM050_01380	COG1136	(ABC) transporter
FM050_01480	COG3344	reverse transcriptase
FM050_01500	COG0457	Tetratricopeptide repeat
FM050_01540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FM050_01580	COG2828	Protein conserved in bacteria
FM050_01595	COG0675	Transposase, IS605 OrfB family
FM050_01630	COG0640	Transcriptional regulator
FM050_01665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_01675	COG0583	DNA-binding transcription factor activity
FM050_01740	COG0840	transmembrane signaling receptor activity
FM050_01745	COG0490	domain, Protein
FM050_01750	COG0475	glutathione-regulated potassium exporter activity
FM050_01755	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_01755	COG3409	Peptidoglycan-binding domain 1 protein
FM050_01800	COG0840	transmembrane signaling receptor activity
FM050_01840	COG4824	toxin secretion phage lysis holin
FM050_01865	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FM050_01950	COG0402	S-adenosylhomocysteine deaminase activity
FM050_01955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_01960	COG0583	DNA-binding transcription factor activity
FM050_01995	COG4974	Belongs to the 'phage' integrase family
FM050_02010	COG4166	transmembrane transport
FM050_02015	COG2002	toxin-antitoxin pair type II binding
FM050_02040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FM050_02065	COG0730	response to heat
FM050_02110	COG0655	NAD(P)H dehydrogenase (quinone) activity
FM050_02115	COG0583	DNA-binding transcription factor activity
FM050_02140	COG0457	Tetratricopeptide repeat
FM050_02160	COG2311	Membrane
FM050_02205	COG3344	reverse transcriptase
FM050_02225	COG3344	reverse transcriptase
FM050_02260	COG2814	Major facilitator Superfamily
FM050_02280	COG3344	reverse transcriptase
FM050_02465	COG3344	reverse transcriptase
FM050_02490	COG3344	reverse transcriptase
FM050_02520	COG1484	DNA-dependent DNA replication
FM050_02665	COG0457	Tetratricopeptide repeat
FM050_02680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FM050_02685	COG0494	nUDIX hydrolase
FM050_02690	COG0542	response to heat
FM050_02720	COG1522	sequence-specific DNA binding
FM050_02725	COG0288	reversible hydration of carbon dioxide
FM050_02730	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FM050_02735	COG2233	PERMEase
FM050_02755	COG1687	branched-chain amino acid
FM050_02760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FM050_02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_02770	COG1361	Conserved repeat domain
FM050_02800	COG0741	lytic transglycosylase activity
FM050_02805	COG0739	heme binding
FM050_02825	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_02990	COG1484	DNA-dependent DNA replication
FM050_03015	COG1024	Enoyl-CoA hydratase
FM050_03020	COG1216	Glycosyl transferase, family 2
FM050_03035	COG1396	sequence-specific DNA binding
FM050_03065	COG0667	Aldo Keto reductase
FM050_03130	COG0300	oxidoreductase activity
FM050_03130	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_03130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FM050_03130	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_03130	COG3321	synthase
FM050_03130	COG0300	oxidoreductase activity
FM050_03130	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_03130	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_03130	COG3321	synthase
FM050_03130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FM050_03150	COG1960	acyl-CoA dehydrogenase activity
FM050_03165	COG1250	3-hydroxyacyl-CoA dehydrogenase
FM050_03170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FM050_03185	COG0300	oxidoreductase activity
FM050_03185	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_03185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FM050_03185	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_03185	COG3321	synthase
FM050_03190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FM050_03245	COG1475	DNA binding
FM050_03265	COG1132	(ABC) transporter
FM050_03295	COG0457	Tetratricopeptide repeat
FM050_03310	COG3011	Protein conserved in bacteria
FM050_03340	COG3227	Zinc metalloprotease (Elastase)
FM050_03355	COG3409	Peptidoglycan-binding domain 1 protein
FM050_03355	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_03405	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FM050_03425	COG1131	(ABC) transporter
FM050_03435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FM050_03440	COG1132	(ABC) transporter
FM050_03530	COG4974	Belongs to the 'phage' integrase family
FM050_03550	COG0457	Tetratricopeptide repeat
FM050_03585	COG3104	oligopeptide transport
FM050_03605	COG1073	alpha beta
FM050_03615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_03635	COG4974	Belongs to the 'phage' integrase family
FM050_03660	COG3344	reverse transcriptase
FM050_03695	COG5444	nuclease activity
FM050_03720	COG4824	toxin secretion phage lysis holin
FM050_03740	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FM050_03755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FM050_03830	COG4974	Belongs to the 'phage' integrase family
FM050_03845	COG4166	transmembrane transport
FM050_03850	COG2002	toxin-antitoxin pair type II binding
FM050_03880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FM050_03905	COG0457	Tetratricopeptide repeat
FM050_03910	COG2801	Transposase and inactivated derivatives
FM050_03975	COG2311	Membrane
FM050_04035	COG0592	DNA-directed DNA polymerase activity
FM050_04040	COG2501	S4 domain
FM050_04050	COG0187	DNA topoisomerase II activity
FM050_04055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FM050_04090	COG0516	GMP reductase activity
FM050_04090	COG0517	IMP dehydrogenase activity
FM050_04095	COG1686	Belongs to the peptidase S11 family
FM050_04125	COG1428	Deoxynucleoside kinase
FM050_04130	COG1428	Deoxynucleoside kinase
FM050_04135	COG1335	isochorismatase
FM050_04145	COG0590	tRNA wobble adenosine to inosine editing
FM050_04155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FM050_04210	COG1982	Orn Lys Arg decarboxylase major
FM050_04220	COG0470	DNA polymerase III
FM050_04225	COG1774	PSP1 C-terminal conserved region
FM050_04235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FM050_04245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FM050_04250	COG2002	toxin-antitoxin pair type II binding
FM050_04260	COG0084	hydrolase, TatD family'
FM050_04280	COG4466	Protein conserved in bacteria
FM050_04295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FM050_04300	COG0251	oxidation-reduction process
FM050_04330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FM050_04335	COG2002	toxin-antitoxin pair type II binding
FM050_04340	COG2244	polysaccharide biosynthetic process
FM050_04345	COG3956	TIGRFAM MazG family protein
FM050_04350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FM050_04370	COG1098	S1 RNA binding domain
FM050_04385	COG2208	phosphoserine phosphatase activity
FM050_04395	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FM050_04400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FM050_04415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FM050_04420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FM050_04425	COG0512	Glutamine amidotransferase of anthranilate synthase
FM050_04430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM050_04435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FM050_04440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FM050_04445	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FM050_04450	COG1396	sequence-specific DNA binding
FM050_04455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FM050_04545	COG3880	PFAM UvrB UvrC protein
FM050_04555	COG0542	response to heat
FM050_04560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FM050_04570	COG4956	integral membrane protein (PIN domain superfamily)
FM050_04590	COG1045	serine acetyltransferase
FM050_04605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FM050_04610	COG3688	RNA-binding protein containing a PIN domain
FM050_04625	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FM050_04630	COG0250	Participates in transcription elongation, termination and antitermination
FM050_04635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FM050_04655	COG2813	Specifically methylates the guanine in position
FM050_04670	COG1358	cellular component organization or biogenesis
FM050_04675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FM050_04745	COG0255	Belongs to the universal ribosomal protein uL29 family
FM050_04805	COG0201	protein transport
FM050_04815	COG0024	Methionine aminopeptidase
FM050_04825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FM050_04860	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FM050_04885	COG0860	N-Acetylmuramoyl-L-alanine amidase
FM050_04890	COG0489	protein tyrosine kinase activity
FM050_04900	COG2194	sulfuric ester hydrolase activity
FM050_04905	COG0726	polysaccharide deacetylase
FM050_04985	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FM050_04990	COG4856	YbbR-like protein
FM050_05025	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_05030	COG2011	ABC-type metal ion transport system permease component
FM050_05035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FM050_05040	COG1464	Belongs to the NlpA lipoprotein family
FM050_05045	COG0604	alcohol dehydrogenase
FM050_05055	COG0277	FAD linked oxidase domain protein
FM050_05060	COG2271	Major facilitator Superfamily
FM050_05070	COG2814	Major facilitator Superfamily
FM050_05085	COG2207	Transcriptional regulator
FM050_05100	COG4166	transmembrane transport
FM050_05105	COG4166	transmembrane transport
FM050_05110	COG0656	L-ascorbic acid biosynthetic process
FM050_05130	COG4149	molybdate abc transporter
FM050_05135	COG0725	ABC transporter, periplasmic molybdate-binding protein
FM050_05140	COG1910	domain protein
FM050_05155	COG0697	spore germination
FM050_05170	COG0204	Acyl-transferase
FM050_05180	COG1609	Transcriptional regulator
FM050_05190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_05215	COG5298	Protein conserved in bacteria
FM050_05235	COG0488	(ABC) transporter
FM050_05250	COG0747	negative chemotaxis
FM050_05255	COG0601	transmembrane transport
FM050_05260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FM050_05265	COG0444	Belongs to the ABC transporter superfamily
FM050_05270	COG4608	Belongs to the ABC transporter superfamily
FM050_05280	COG0561	phosphatase activity
FM050_05300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FM050_05305	COG0179	Fumarylacetoacetate (FAA) hydrolase
FM050_05315	COG0531	amino acid
FM050_05320	COG2814	Major facilitator Superfamily
FM050_05330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FM050_05340	COG4294	response to UV
FM050_05345	COG0705	Rhomboid family
FM050_05355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FM050_05360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FM050_05365	COG0864	Transcriptional regulator
FM050_05370	COG2337	Toxic component of a toxin-antitoxin (TA) module
FM050_05375	COG2183	response to ionizing radiation
FM050_05475	COG0802	atpase or kinase
FM050_05480	COG1214	PFAM Peptidase M22, glycoprotease
FM050_05485	COG0456	acetyltransferase
FM050_05495	COG0488	(ABC) transporter
FM050_05510	COG1266	CAAX protease self-immunity
FM050_05530	COG2252	PERMEase
FM050_05540	COG5002	protein histidine kinase activity
FM050_05570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FM050_05615	COG2205	protein histidine kinase activity
FM050_05620	COG0745	RESPONSE REGULATOR receiver
FM050_05660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FM050_05670	COG1216	Glycosyl transferase, family 2
FM050_05670	COG0463	Glycosyl transferase, family 2
FM050_05690	COG0697	spore germination
FM050_05725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FM050_05730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FM050_05735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FM050_05745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FM050_05760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FM050_05770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FM050_05780	COG0151	Belongs to the GarS family
FM050_05810	COG0210	DNA helicase
FM050_05820	COG4851	CamS sex pheromone cAM373 precursor
FM050_05835	COG1335	isochorismatase
FM050_05850	COG2011	ABC-type metal ion transport system permease component
FM050_05855	COG1464	Belongs to the NlpA lipoprotein family
FM050_05870	COG0003	Pfam Anion-transporting ATPase
FM050_05875	COG1846	Transcriptional regulator
FM050_05880	COG4682	membrane
FM050_05900	COG1597	lipid kinase activity
FM050_05910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FM050_05920	COG1012	belongs to the aldehyde dehydrogenase family
FM050_05925	COG2076	Multidrug Resistance protein
FM050_05935	COG2309	aminopeptidase activity
FM050_05955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM050_05965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FM050_05970	COG4807	Protein conserved in bacteria
FM050_06005	COG1473	amidohydrolase
FM050_06020	COG0450	alkyl hydroperoxide reductase
FM050_06040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_06045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_06050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM050_06060	COG0492	ferredoxin-NADP+ reductase activity
FM050_06075	COG0166	Belongs to the GPI family
FM050_06100	COG5002	protein histidine kinase activity
FM050_06120	COG3541	Predicted nucleotidyltransferase
FM050_06125	COG2814	Major facilitator Superfamily
FM050_06130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM050_06130	COG0723	plastoquinol--plastocyanin reductase activity
FM050_06140	COG0765	amino acid transport
FM050_06145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM050_06155	COG0840	transmembrane signaling receptor activity
FM050_06180	COG0549	Belongs to the carbamate kinase family
FM050_06185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FM050_06200	COG0366	Alpha amylase catalytic
FM050_06205	COG1263	PTS System
FM050_06205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FM050_06205	COG2190	(PTS) system
FM050_06235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FM050_06255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FM050_06265	COG1116	anion transmembrane transporter activity
FM050_06320	COG2270	Major facilitator Superfamily
FM050_06350	COG2310	stress, protein
FM050_06355	COG2310	stress, protein
FM050_06360	COG2310	stress, protein
FM050_06365	COG0861	Integral membrane protein TerC family
FM050_06375	COG3853	Toxic anion resistance protein (TelA)
FM050_06390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FM050_06400	COG1295	ribonuclease BN
FM050_06405	COG2217	Heavy metal translocating P-type atpase
FM050_06410	COG0697	spore germination
FM050_06430	COG0586	Pfam SNARE associated Golgi protein
FM050_06445	COG3871	stress protein (general stress protein 26)
FM050_06450	COG0387	Pfam Sodium calcium exchanger
FM050_06460	COG0535	radical SAM domain protein
FM050_06480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FM050_06485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FM050_06500	COG3829	transcription factor binding
FM050_06510	COG0833	amino acid
FM050_06515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FM050_06545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FM050_06545	COG1263	PTS System
FM050_06550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FM050_06565	COG0463	Glycosyl transferase, family 2
FM050_06575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FM050_06575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FM050_06595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FM050_06615	COG1228	amidohydrolase
FM050_06620	COG1090	epimerase
FM050_06650	COG1988	membrane-bound metal-dependent
FM050_06655	COG1194	a g-specific adenine glycosylase
FM050_06680	COG1132	(ABC) transporter
FM050_06685	COG4129	membrane
FM050_06690	COG0070	glutamate synthase
FM050_06690	COG0069	glutamate synthase activity
FM050_06690	COG0067	glutamate synthase
FM050_06705	COG4555	ABC transporter
FM050_06725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FM050_06730	COG0735	belongs to the Fur family
FM050_06835	COG4974	Belongs to the 'phage' integrase family
FM050_06860	COG0582	viral genome integration into host DNA
FM050_06920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FM050_06945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FM050_06950	COG5001	Diguanylate cyclase
FM050_06950	COG1716	ATPase activity
FM050_06955	COG2766	serine protein kinase
FM050_06975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FM050_06985	COG1585	Membrane protein implicated in regulation of membrane protease activity
FM050_06990	COG2268	Band 7 protein
FM050_07000	COG3290	protein histidine kinase activity
FM050_07005	COG4565	transcriptional regulatory protein
FM050_07010	COG2851	Citrate transporter
FM050_07035	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FM050_07040	COG3842	ATPase activity
FM050_07045	COG1175	transmembrane transport
FM050_07050	COG0395	ABC-type sugar transport system, permease component
FM050_07060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FM050_07065	COG0745	RESPONSE REGULATOR receiver
FM050_07070	COG5002	protein histidine kinase activity
FM050_07070	COG3850	Histidine kinase
FM050_07080	COG4990	cell redox homeostasis
FM050_07090	COG3290	protein histidine kinase activity
FM050_07095	COG4565	transcriptional regulatory protein
FM050_07100	COG3493	citrate carrier protein
FM050_07105	COG0281	malic enzyme
FM050_07115	COG0697	spore germination
FM050_07120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_07130	COG5002	protein histidine kinase activity
FM050_07135	COG0745	RESPONSE REGULATOR receiver
FM050_07145	COG0456	acetyltransferase
FM050_07145	COG0454	-acetyltransferase
FM050_07150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FM050_07155	COG3383	formate dehydrogenase (NAD+) activity
FM050_07160	COG2427	Protein of unknown function (DUF1641)
FM050_07185	COG0640	Transcriptional regulator
FM050_07190	COG2217	Heavy metal translocating P-type atpase
FM050_07195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FM050_07210	COG3227	Zinc metalloprotease (Elastase)
FM050_07230	COG2720	vancomycin resistance protein
FM050_07235	COG1316	TRANSCRIPTIONal
FM050_07240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM050_07245	COG0346	lactoylglutathione lyase activity
FM050_07250	COG1253	flavin adenine dinucleotide binding
FM050_07255	COG1027	Aspartate ammonia-lyase
FM050_07260	COG1620	l-lactate permease
FM050_07275	COG3104	oligopeptide transport
FM050_07280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM050_07285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_07290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_07300	COG2226	methyltransferase
FM050_07310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FM050_07320	COG4548	von Willebrand factor, type A
FM050_07325	COG0714	Associated with various cellular activities
FM050_07345	COG0531	amino acid
FM050_07350	COG2188	Transcriptional regulator
FM050_07355	COG1263	PTS System
FM050_07355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FM050_07360	COG0366	Alpha amylase catalytic
FM050_07375	COG0697	spore germination
FM050_07380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FM050_07385	COG1115	amino acid carrier protein
FM050_07395	COG1126	abc transporter atp-binding protein
FM050_07400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM050_07405	COG0765	amino acid transport
FM050_07410	COG0765	amino acid transport
FM050_07415	COG0833	amino acid
FM050_07430	COG1595	DNA-templated transcription, initiation
FM050_07440	COG2378	regulation of single-species biofilm formation
FM050_07445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FM050_07450	COG5002	protein histidine kinase activity
FM050_07495	COG1846	Transcriptional regulator
FM050_07500	COG0477	Major facilitator Superfamily
FM050_07505	COG1609	Transcriptional regulator
FM050_07510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FM050_07525	COG1172	Belongs to the binding-protein-dependent transport system permease family
FM050_07530	COG1879	ABC-type sugar transport system periplasmic component
FM050_07560	COG1063	alcohol dehydrogenase
FM050_07615	COG0840	transmembrane signaling receptor activity
FM050_07620	COG3583	domain protein
FM050_07620	COG3584	3D domain protein
FM050_07625	COG1476	TRANSCRIPTIONal
FM050_07645	COG3104	oligopeptide transport
FM050_07650	COG1114	Component of the transport system for branched-chain amino acids
FM050_07665	COG1113	amino acid transport
FM050_07670	COG2252	PERMEase
FM050_07685	COG2153	protein acetylation
FM050_07695	COG0475	glutathione-regulated potassium exporter activity
FM050_07695	COG0569	domain protein
FM050_07705	COG1845	cytochrome c oxidase, subunit III
FM050_07710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FM050_07720	COG0833	amino acid
FM050_07725	COG4990	cell redox homeostasis
FM050_07740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FM050_07745	COG0697	spore germination
FM050_07750	COG0531	amino acid
FM050_07760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FM050_07765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FM050_07770	COG1918	ferrous iron import across plasma membrane
FM050_07770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FM050_07775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FM050_07780	COG0573	inorganic phosphate transmembrane transporter activity
FM050_07785	COG0581	inorganic phosphate transmembrane transporter activity
FM050_07790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM050_07910	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FM050_07930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FM050_07935	COG1116	anion transmembrane transporter activity
FM050_07940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FM050_07945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FM050_07950	COG0352	thiamine-phosphate diphosphorylase activity
FM050_07955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM050_07960	COG2104	thiamine diphosphate biosynthetic process
FM050_07970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FM050_07975	COG0351	phosphomethylpyrimidine kinase
FM050_08015	COG2205	protein histidine kinase activity
FM050_08020	COG2814	Major facilitator Superfamily
FM050_08025	COG1846	Transcriptional regulator
FM050_08050	COG1136	(ABC) transporter
FM050_08060	COG2252	PERMEase
FM050_08065	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_08125	COG0778	Nitroreductase
FM050_08130	COG2719	SpoVR family
FM050_08140	COG3591	Belongs to the peptidase S1B family
FM050_08150	COG0446	pyridine nucleotide-disulphide oxidoreductase
FM050_08155	COG1937	Protein conserved in bacteria
FM050_08160	COG0425	Belongs to the sulfur carrier protein TusA family
FM050_08160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM050_08165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_08165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM050_08170	COG0425	Belongs to the sulfur carrier protein TusA family
FM050_08185	COG2210	Belongs to the sulfur carrier protein TusA family
FM050_08190	COG0730	response to heat
FM050_08200	COG1316	TRANSCRIPTIONal
FM050_08205	COG0604	alcohol dehydrogenase
FM050_08210	COG1283	sodium-dependent phosphate transmembrane transporter activity
FM050_08230	COG3711	transcriptional antiterminator
FM050_08230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FM050_08235	COG1447	Phosphotransferase system cellobiose-specific component IIA
FM050_08240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FM050_08265	COG1388	LysM domain
FM050_08265	COG3584	3D domain protein
FM050_08270	COG0577	efflux transmembrane transporter activity
FM050_08275	COG1136	(ABC) transporter
FM050_08285	COG5522	Integral membrane protein (intg_mem_TP0381)
FM050_08300	COG1114	Component of the transport system for branched-chain amino acids
FM050_08305	COG3546	catalase activity
FM050_08340	COG0586	Pfam SNARE associated Golgi protein
FM050_08370	COG0531	amino acid
FM050_08375	COG0475	glutathione-regulated potassium exporter activity
FM050_08385	COG1737	Transcriptional regulator
FM050_08395	COG1263	PTS System
FM050_08395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FM050_08405	COG2259	Doxx family
FM050_08425	COG1522	sequence-specific DNA binding
FM050_08430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FM050_08430	COG0165	Argininosuccinate lyase
FM050_08435	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_08455	COG1309	transcriptional regulator
FM050_08460	COG2814	Major facilitator Superfamily
FM050_08465	COG1733	regulation of RNA biosynthetic process
FM050_08480	COG4533	DNA binding
FM050_08485	COG2211	Major facilitator Superfamily
FM050_08495	COG0693	protein deglycase activity
FM050_08500	COG0753	catalase activity
FM050_08510	COG0531	amino acid
FM050_08525	COG1012	belongs to the aldehyde dehydrogenase family
FM050_08540	COG1132	(ABC) transporter
FM050_08545	COG1132	(ABC) transporter
FM050_08555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM050_08560	COG0765	amino acid transport
FM050_08565	COG1126	abc transporter atp-binding protein
FM050_08580	COG0189	ligase activity
FM050_08610	COG0028	Belongs to the TPP enzyme family
FM050_08615	COG3527	Alpha-acetolactate decarboxylase
FM050_08630	COG0561	phosphatase activity
FM050_08640	COG3409	Peptidoglycan-binding domain 1 protein
FM050_08640	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_08645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM050_08650	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_08665	COG0659	secondary active sulfate transmembrane transporter activity
FM050_08670	COG2244	polysaccharide biosynthetic process
FM050_08690	COG1024	Enoyl-CoA hydratase
FM050_08710	COG1363	Peptidase, m42
FM050_08750	COG0601	transmembrane transport
FM050_08755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FM050_08760	COG0444	Belongs to the ABC transporter superfamily
FM050_08765	COG4608	Belongs to the ABC transporter superfamily
FM050_08780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_08785	COG1484	DNA-dependent DNA replication
FM050_08890	COG0477	Major facilitator Superfamily
FM050_08895	COG3290	protein histidine kinase activity
FM050_08900	COG4565	transcriptional regulatory protein
FM050_08905	COG3181	Tripartite tricarboxylate transporter family receptor
FM050_08910	COG0494	nUDIX hydrolase
FM050_08925	COG0305	Participates in initiation and elongation during chromosome replication
FM050_08945	COG0305	Participates in initiation and elongation during chromosome replication
FM050_08970	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FM050_08975	COG1288	antiporter activity
FM050_08990	COG1842	Phage shock protein A
FM050_09000	COG0477	Major facilitator Superfamily
FM050_09020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_09080	COG2020	methyltransferase activity
FM050_09110	COG3344	reverse transcriptase
FM050_09125	COG1073	alpha beta
FM050_09135	COG2801	Transposase and inactivated derivatives
FM050_09170	COG0577	efflux transmembrane transporter activity
FM050_09175	COG1136	(ABC) transporter
FM050_09210	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FM050_09215	COG1522	sequence-specific DNA binding
FM050_09235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FM050_09290	COG1183	phosphatidylcholine synthase activity
FM050_09305	COG2814	Major facilitator Superfamily
FM050_09310	COG0640	Transcriptional regulator
FM050_09340	COG2376	Dihydroxyacetone kinase
FM050_09355	COG2376	Dihydroxyacetone kinase
FM050_09400	COG2373	Large extracellular alpha-helical protein
FM050_09480	COG1191	sigma factor activity
FM050_09490	COG2208	phosphoserine phosphatase activity
FM050_09495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FM050_09500	COG0784	Response regulator, receiver
FM050_09500	COG2205	protein histidine kinase activity
FM050_09500	COG5002	protein histidine kinase activity
FM050_09530	COG2807	transmembrane transport
FM050_09535	COG2186	Transcriptional regulator
FM050_09545	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FM050_09565	COG0420	3'-5' exonuclease activity
FM050_09570	COG4717	serine-type aminopeptidase activity
FM050_09580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FM050_09600	COG0346	lactoylglutathione lyase activity
FM050_09605	COG0346	lactoylglutathione lyase activity
FM050_09610	COG0457	Tetratricopeptide repeat
FM050_09620	COG2267	carboxylic ester hydrolase activity
FM050_09635	COG2140	Oxalate decarboxylase
FM050_09645	COG3620	sequence-specific DNA binding
FM050_09650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FM050_09655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FM050_09665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FM050_09680	COG1595	DNA-templated transcription, initiation
FM050_09690	COG0772	Belongs to the SEDS family
FM050_09695	COG3973	AAA domain
FM050_09730	COG4980	gas vesicle protein
FM050_09735	COG0537	adenosine 5'-monophosphoramidase activity
FM050_09740	COG1131	(ABC) transporter
FM050_09745	COG4473	ABC transporter
FM050_09760	COG1309	transcriptional regulator
FM050_09765	COG3402	PFAM membrane-flanked domain
FM050_09770	COG3428	Bacterial PH domain
FM050_09805	COG0697	spore germination
FM050_09810	COG3402	PFAM membrane-flanked domain
FM050_09815	COG3428	Bacterial PH domain
FM050_09820	COG2329	Antibiotic biosynthesis monooxygenase
FM050_09825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FM050_09840	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FM050_09875	COG1484	DNA-dependent DNA replication
FM050_09890	COG1309	transcriptional regulator
FM050_09925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_09930	COG1609	Transcriptional regulator
FM050_09940	COG1234	tRNA 3'-trailer cleavage
FM050_09945	COG0095	Lipoate-protein ligase
FM050_09955	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_09965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FM050_09975	COG4208	sulfate ABC transporter
FM050_10070	COG1073	alpha beta
FM050_10075	COG1408	metallophosphoesterase
FM050_10080	COG1078	dGTPase activity
FM050_10090	COG1595	DNA-templated transcription, initiation
FM050_10100	COG2207	Transcriptional regulator
FM050_10100	COG3708	Transcriptional regulator
FM050_10110	COG2205	protein histidine kinase activity
FM050_10115	COG0745	RESPONSE REGULATOR receiver
FM050_10135	COG0501	Belongs to the peptidase M48B family
FM050_10140	COG0840	transmembrane signaling receptor activity
FM050_10145	COG3693	PFAM glycoside hydrolase, family 10
FM050_10155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FM050_10160	COG2224	Isocitrate lyase
FM050_10175	COG1278	Cold shock
FM050_10195	COG0398	Pfam SNARE associated Golgi protein
FM050_10255	COG0179	Fumarylacetoacetate (FAA) hydrolase
FM050_10280	COG0367	asparagine synthase
FM050_10290	COG0753	catalase activity
FM050_10300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FM050_10325	COG3339	Conserved Protein
FM050_10330	COG0004	ammonium transporteR
FM050_10350	COG2996	Protein conserved in bacteria
FM050_10375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_10390	COG0561	phosphatase activity
FM050_10410	COG2267	carboxylic ester hydrolase activity
FM050_10425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FM050_10430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FM050_10435	COG5504	Zn-dependent protease
FM050_10445	COG0180	Tryptophanyl-tRNA synthetase
FM050_10460	COG4166	transmembrane transport
FM050_10465	COG0601	transmembrane transport
FM050_10470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FM050_10475	COG0444	Belongs to the ABC transporter superfamily
FM050_10480	COG4608	Belongs to the ABC transporter superfamily
FM050_10485	COG0534	Mate efflux family protein
FM050_10490	COG4166	transmembrane transport
FM050_10505	COG0861	Integral membrane protein TerC family
FM050_10515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FM050_10525	COG1164	Oligoendopeptidase f
FM050_10535	COG2346	COG2346, Truncated hemoglobins
FM050_10540	COG4116	CYTH
FM050_10550	COG2357	RelA SpoT domain protein
FM050_10560	COG0564	pseudouridine synthase activity
FM050_10575	COG0772	Belongs to the SEDS family
FM050_10580	COG1216	Glycosyl transferase, family 2
FM050_10600	COG0457	Tetratricopeptide repeat
FM050_10600	COG0463	Glycosyl transferase, family 2
FM050_10620	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FM050_10635	COG1091	dTDP-4-dehydrorhamnose reductase activity
FM050_10680	COG2153	protein acetylation
FM050_10690	COG2382	esterase
FM050_10715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FM050_10725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FM050_10725	COG0512	Glutamine amidotransferase of anthranilate synthase
FM050_10760	COG1620	l-lactate permease
FM050_10765	COG5634	Uncharacterized conserved protein (DUF2278)
FM050_10805	COG2226	methyltransferase
FM050_10825	COG0508	dehydrogenase complex catalyzes the overall conversion of
FM050_10835	COG1476	TRANSCRIPTIONal
FM050_10875	COG4152	abc transporter atp-binding protein
FM050_10880	COG1668	transmembrane transport
FM050_10900	COG2226	methyltransferase
FM050_10910	COG1686	Belongs to the peptidase S11 family
FM050_10915	COG0681	Belongs to the peptidase S26 family
FM050_10950	COG1012	belongs to the aldehyde dehydrogenase family
FM050_10960	COG1176	ABC-type spermidine putrescine transport system, permease component I
FM050_10965	COG1177	transmembrane transport
FM050_10980	COG2409	Drug exporters of the RND superfamily
FM050_10990	COG0564	pseudouridine synthase activity
FM050_11000	COG2340	Cysteine-rich secretory protein family
FM050_11005	COG0247	lactate metabolic process
FM050_11010	COG0277	FAD linked oxidase domain protein
FM050_11015	COG3835	regulator
FM050_11025	COG0745	RESPONSE REGULATOR receiver
FM050_11030	COG5002	protein histidine kinase activity
FM050_11035	COG2186	Transcriptional regulator
FM050_11055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FM050_11065	COG2116	formate transmembrane transporter activity
FM050_11070	COG0861	Integral membrane protein TerC family
FM050_11075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FM050_11085	COG2030	dehydratase
FM050_11105	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_11110	COG3243	poly(R)-hydroxyalkanoic acid synthase
FM050_11120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FM050_11135	COG1840	ABC-type Fe3 transport system, periplasmic component
FM050_11140	COG3842	ATPase activity
FM050_11165	COG1349	DNA-binding transcription factor activity
FM050_11180	COG0235	Class ii aldolase
FM050_11190	COG2861	carbohydrate metabolic process
FM050_11200	COG3852	Histidine kinase
FM050_11205	COG1846	Transcriptional regulator
FM050_11215	COG2318	DinB family
FM050_11220	COG5002	protein histidine kinase activity
FM050_11230	COG0720	synthase
FM050_11245	COG4873	Protein conserved in bacteria
FM050_11275	COG1780	Probably involved in ribonucleotide reductase function
FM050_11280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FM050_11295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FM050_11300	COG1725	Transcriptional regulator
FM050_11305	COG1131	(ABC) transporter
FM050_11315	COG1131	(ABC) transporter
FM050_11335	COG1522	sequence-specific DNA binding
FM050_11345	COG1335	isochorismatase
FM050_11355	COG1619	proteins homologs of microcin C7 resistance protein MccF
FM050_11360	COG2070	2-Nitropropane dioxygenase
FM050_11365	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FM050_11375	COG1696	Membrane protein involved in D-alanine export
FM050_11400	COG0716	FMN binding
FM050_11440	COG1846	Transcriptional regulator
FM050_11450	COG1301	dicarboxylic acid transport
FM050_11455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FM050_11460	COG4709	membrane
FM050_11465	COG3874	Sporulation protein YtfJ
FM050_11485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM050_11490	COG0028	Belongs to the TPP enzyme family
FM050_11495	COG0440	acetolactate synthase activity
FM050_11570	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FM050_11585	COG1183	phosphatidylcholine synthase activity
FM050_11590	COG1368	sulfuric ester hydrolase activity
FM050_11600	COG0019	diaminopimelate decarboxylase activity
FM050_11620	COG0529	Catalyzes the synthesis of activated sulfate
FM050_11625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FM050_11645	COG1648	precorrin-2 dehydrogenase activity
FM050_11650	COG0733	neurotransmitter:sodium symporter activity
FM050_11670	COG1757	Na H antiporter
FM050_11685	COG4758	membrane
FM050_11690	COG4585	Histidine kinase
FM050_11695	COG2197	response regulator
FM050_11705	COG1114	Component of the transport system for branched-chain amino acids
FM050_11755	COG0730	response to heat
FM050_11760	COG0306	phosphate transporter
FM050_11765	COG1392	Phosphate transport regulator
FM050_11770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FM050_11785	COG3852	Histidine kinase
FM050_11790	COG1801	Protein of unknown function DUF72
FM050_11800	COG0582	viral genome integration into host DNA
FM050_11805	COG5002	protein histidine kinase activity
FM050_11825	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FM050_11825	COG0392	lysyltransferase activity
FM050_11840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FM050_11845	COG1686	Belongs to the peptidase S11 family
FM050_11850	COG2715	membrane protein required for spore maturation
FM050_11855	COG0700	Nucleoside recognition
FM050_11860	COG1187	pseudouridine synthase activity
FM050_11870	COG1333	cytochrome c biogenesis protein
FM050_11875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FM050_11880	COG0745	RESPONSE REGULATOR receiver
FM050_11885	COG5002	protein histidine kinase activity
FM050_11890	COG2096	Adenosyltransferase
FM050_11905	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FM050_11910	COG1141	Ferredoxin
FM050_11920	COG0514	ATP-dependent DNA helicase (RecQ)
FM050_11925	COG1266	CAAX protease self-immunity
FM050_11935	COG1408	metallophosphoesterase
FM050_11940	COG0789	Transcriptional regulator
FM050_11950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FM050_11970	COG0492	ferredoxin-NADP+ reductase activity
FM050_11975	COG0252	asparaginase activity
FM050_12040	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FM050_12055	COG0142	geranyltranstransferase activity
FM050_12065	COG0142	geranyltranstransferase activity
FM050_12095	COG0457	Tetratricopeptide repeat
FM050_12115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FM050_12120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FM050_12120	COG2010	Cytochrome c
FM050_12125	COG4347	Protein of unknown function (DUF1405)
FM050_12140	COG2738	Putative neutral zinc metallopeptidase
FM050_12150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_12160	COG1694	Mazg nucleotide pyrophosphohydrolase
FM050_12180	COG0438	transferase activity, transferring glycosyl groups
FM050_12220	COG1199	ATP-dependent helicase activity
FM050_12220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FM050_12240	COG3935	DnaD domain protein
FM050_12245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FM050_12255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FM050_12255	COG4499	WXG100 protein secretion system (Wss), protein YukC
FM050_12310	COG0116	Belongs to the methyltransferase superfamily
FM050_12320	COG1199	ATP-dependent helicase activity
FM050_12325	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FM050_12335	COG0024	Methionine aminopeptidase
FM050_12350	COG2233	PERMEase
FM050_12355	COG2311	Membrane
FM050_12360	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FM050_12370	COG0456	acetyltransferase
FM050_12400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM050_12415	COG3944	biosynthesis protein
FM050_12425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FM050_12440	COG1215	transferase activity, transferring glycosyl groups
FM050_12445	COG0438	transferase activity, transferring glycosyl groups
FM050_12460	COG0454	-acetyltransferase
FM050_12480	COG0328	RNA-DNA hybrid ribonuclease activity
FM050_12515	COG3403	YqcI/YcgG family
FM050_12520	COG1280	lysine exporter protein (LysE YggA)
FM050_12540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FM050_12545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FM050_12555	COG0475	glutathione-regulated potassium exporter activity
FM050_12560	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FM050_12565	COG0789	Transcriptional regulator
FM050_12565	COG4978	Transcriptional regulator
FM050_12575	COG2323	membrane
FM050_12580	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FM050_12620	COG1923	regulation of RNA biosynthetic process
FM050_12630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FM050_12635	COG1360	Flagellar Motor Protein
FM050_12640	COG2201	protein-glutamate methylesterase activity
FM050_12645	COG0643	Histidine kinase
FM050_12645	COG2198	Histidine kinase
FM050_12650	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM050_12650	COG1776	CheC inhibitor of MCP methylation
FM050_12665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FM050_12685	COG1256	bacterial-type flagellum assembly
FM050_12690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FM050_12710	COG1815	bacterial-type flagellum-dependent cell motility
FM050_12715	COG1558	bacterial-type flagellum-dependent cell motility
FM050_12725	COG1766	The M ring may be actively involved in energy transduction
FM050_12730	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM050_12740	COG1157	protein secretion by the type III secretion system
FM050_12775	COG0835	chemotaxis
FM050_12775	COG0784	Response regulator, receiver
FM050_12795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FM050_12800	COG0741	lytic transglycosylase activity
FM050_12810	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM050_12815	COG1776	CheC inhibitor of MCP methylation
FM050_12815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM050_12825	COG1338	Plays a role in the flagellum-specific transport system
FM050_12830	COG1987	bacterial-type flagellum assembly
FM050_12840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FM050_12845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FM050_12850	COG1419	protein localization to endoplasmic reticulum
FM050_12855	COG4786	Flagellar basal body rod
FM050_12860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FM050_12895	COG2329	Antibiotic biosynthesis monooxygenase
FM050_12920	COG0583	DNA-binding transcription factor activity
FM050_12925	COG3842	ATPase activity
FM050_12965	COG1686	Belongs to the peptidase S11 family
FM050_12970	COG0406	alpha-ribazole phosphatase activity
FM050_13000	COG0367	asparagine synthase
FM050_13030	COG1802	Transcriptional regulator
FM050_13035	COG0697	spore germination
FM050_13045	COG0523	cobalamin synthesis protein
FM050_13055	COG0701	Predicted permease
FM050_13070	COG1757	Na H antiporter
FM050_13075	COG0789	Transcriptional regulator
FM050_13100	COG0534	Mate efflux family protein
FM050_13105	COG3340	Belongs to the peptidase S51 family
FM050_13125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM050_13145	COG2733	membrane
FM050_13185	COG1131	(ABC) transporter
FM050_13205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FM050_13210	COG0528	UMP kinase activity
FM050_13220	COG1027	Aspartate ammonia-lyase
FM050_13225	COG0281	malic enzyme
FM050_13230	COG4191	Histidine kinase
FM050_13235	COG0784	Response regulator, receiver
FM050_13240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FM050_13255	COG3620	sequence-specific DNA binding
FM050_13310	COG1695	Transcriptional regulator
FM050_13320	COG0477	Major facilitator Superfamily
FM050_13330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FM050_13335	COG2223	nitrite transmembrane transporter activity
FM050_13340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FM050_13360	COG0733	neurotransmitter:sodium symporter activity
FM050_13365	COG5566	PFAM Mor transcription activator
FM050_13370	COG2323	membrane
FM050_13390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FM050_13400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM050_13405	COG0028	Belongs to the TPP enzyme family
FM050_13425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FM050_13450	COG2814	Major facilitator Superfamily
FM050_13455	COG3384	dioxygenase
FM050_13465	COG3279	Response regulator of the LytR AlgR family
FM050_13470	COG0427	acetyl-CoA hydrolase
FM050_13490	COG4166	transmembrane transport
FM050_13495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_13500	COG1914	H( )-stimulated, divalent metal cation uptake system
FM050_13515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FM050_13520	COG0531	amino acid
FM050_13555	COG1309	transcriptional regulator
FM050_13560	COG2390	Transcriptional regulator
FM050_13570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM050_13575	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FM050_13590	COG4846	Membrane protein involved in cytochrome C biogenesis
FM050_13600	COG0006	proline dipeptidase activity
FM050_13610	COG2132	Multicopper oxidase
FM050_13625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FM050_13645	COG1114	Component of the transport system for branched-chain amino acids
FM050_13660	COG1276	copper resistance
FM050_13660	COG2372	response to copper ion
FM050_13665	COG4549	nuclear export factor GLE1
FM050_13675	COG0697	spore germination
FM050_13680	COG0583	DNA-binding transcription factor activity
FM050_13685	COG1959	2 iron, 2 sulfur cluster binding
FM050_13690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FM050_13695	COG0778	Nitroreductase
FM050_13705	COG0628	permease
FM050_13715	COG1231	oxidoreductase activity
FM050_13725	COG0523	cobalamin synthesis protein
FM050_13735	COG0411	ABC transporter
FM050_13755	COG0583	DNA-binding transcription factor activity
FM050_13790	COG1271	oxidase subunit
FM050_13795	COG1294	oxidase, subunit
FM050_13800	COG4988	ABC transporter
FM050_13805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FM050_13815	COG1216	Glycosyl transferase, family 2
FM050_13855	COG1686	Belongs to the peptidase S11 family
FM050_13870	COG0791	NLP P60 protein
FM050_13870	COG1388	LysM domain
FM050_13880	COG1132	(ABC) transporter
FM050_13885	COG0745	RESPONSE REGULATOR receiver
FM050_13890	COG5002	protein histidine kinase activity
FM050_13895	COG0300	oxidoreductase activity
FM050_13925	COG0460	homoserine dehydrogenase
FM050_13950	COG1316	TRANSCRIPTIONal
FM050_13970	COG0745	RESPONSE REGULATOR receiver
FM050_13975	COG5002	protein histidine kinase activity
FM050_13990	COG1285	pathogenesis
FM050_13995	COG1247	-acetyltransferase
FM050_14025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FM050_14035	COG1082	Xylose isomerase domain protein TIM barrel
FM050_14045	COG2814	Major facilitator Superfamily
FM050_14050	COG1279	arginine transmembrane transporter activity
FM050_14055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_14065	COG1752	Esterase of the alpha-beta hydrolase superfamily
FM050_14100	COG0577	efflux transmembrane transporter activity
FM050_14105	COG2002	toxin-antitoxin pair type II binding
FM050_14110	COG1404	Belongs to the peptidase S8 family
FM050_14115	COG0640	Transcriptional regulator
FM050_14120	COG0667	Aldo Keto reductase
FM050_14125	COG2814	Major facilitator Superfamily
FM050_14135	COG3152	Membrane
FM050_14160	COG0840	transmembrane signaling receptor activity
FM050_14175	COG3949	Membrane
FM050_14180	COG0783	Belongs to the Dps family
FM050_14195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FM050_14205	COG1231	oxidoreductase activity
FM050_14210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_14215	COG4989	oxidoreductase activity
FM050_14225	COG0523	cobalamin synthesis protein
FM050_14230	COG0456	acetyltransferase
FM050_14235	COG0803	Belongs to the bacterial solute-binding protein 9 family
FM050_14240	COG0702	epimerase
FM050_14250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FM050_14260	COG4166	transmembrane transport
FM050_14285	COG5337	Spore coat protein CotH
FM050_14290	COG1051	belongs to the nudix hydrolase family
FM050_14295	COG0586	Pfam SNARE associated Golgi protein
FM050_14310	COG0701	Predicted permease
FM050_14315	COG3689	TIGRFAM TIGR03943 family protein
FM050_14320	COG1607	acyl-coa hydrolase
FM050_14330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FM050_14345	COG0702	epimerase
FM050_14350	COG2839	Protein conserved in bacteria
FM050_14355	COG1253	flavin adenine dinucleotide binding
FM050_14375	COG1114	Component of the transport system for branched-chain amino acids
FM050_14380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM050_14400	COG0860	N-Acetylmuramoyl-L-alanine amidase
FM050_14410	COG1876	peptidase activity
FM050_14425	COG2211	Major facilitator Superfamily
FM050_14440	COG0860	N-Acetylmuramoyl-L-alanine amidase
FM050_14450	COG0561	phosphatase activity
FM050_14465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FM050_14485	COG1819	glycosyl
FM050_14490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_14495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_14525	COG0456	acetyltransferase
FM050_14560	COG4499	WXG100 protein secretion system (Wss), protein YukC
FM050_14625	COG3874	Sporulation protein YtfJ
FM050_14650	COG2226	methyltransferase
FM050_14675	COG1082	Xylose isomerase domain protein TIM barrel
FM050_14680	COG0346	lactoylglutathione lyase activity
FM050_14695	COG1595	DNA-templated transcription, initiation
FM050_14710	COG0426	domain, Protein
FM050_14710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FM050_14720	COG0386	Belongs to the glutathione peroxidase family
FM050_14730	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FM050_14735	COG0714	Associated with various cellular activities
FM050_14740	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FM050_14745	COG1140	nitrate reductase beta subunit
FM050_14750	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FM050_14755	COG2181	nitrate reductase activity
FM050_14760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FM050_14765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FM050_14770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FM050_14775	COG0303	'Molybdopterin
FM050_14780	COG0314	molybdopterin synthase activity
FM050_14785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FM050_14790	COG2223	nitrite transmembrane transporter activity
FM050_14800	COG1648	precorrin-2 dehydrogenase activity
FM050_14810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FM050_14810	COG1587	Uroporphyrinogen-III synthase
FM050_14815	COG2146	nitrite reductase [NAD(P)H] activity
FM050_14820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FM050_14825	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FM050_14860	COG2359	stage V sporulation protein S
FM050_14885	COG0730	response to heat
FM050_14910	COG0457	Tetratricopeptide repeat
FM050_14925	COG1418	mRNA catabolic process
FM050_14930	COG0488	(ABC) transporter
FM050_14975	COG1476	TRANSCRIPTIONal
FM050_14995	COG0629	single-stranded DNA binding
FM050_15005	COG1413	lyase activity
FM050_15020	COG2521	methyltransferase
FM050_15020	COG2136	Putative SAM-dependent methyltransferase
FM050_15025	COG0018	arginyl-trna synthetase
FM050_15080	COG0017	Asparaginyl-tRNA synthetase
FM050_15110	COG2610	gluconate transmembrane transporter activity
FM050_15120	COG1794	racemase activity, acting on amino acids and derivatives
FM050_15130	COG0456	acetyltransferase
FM050_15140	COG3655	Transcriptional regulator
FM050_15145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FM050_15155	COG1131	(ABC) transporter
FM050_15160	COG4473	ABC transporter
FM050_15170	COG0546	phosphoglycolate phosphatase activity
FM050_15185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FM050_15200	COG0768	penicillin binding
FM050_15210	COG0204	Acyl-transferase
FM050_15220	COG1272	protein, Hemolysin III
FM050_15230	COG0805	protein transport
FM050_15240	COG1307	EDD domain protein, DegV family
FM050_15250	COG1999	signal sequence binding
FM050_15255	COG0071	Belongs to the small heat shock protein (HSP20) family
FM050_15260	COG0367	asparagine synthase
FM050_15275	COG0860	N-Acetylmuramoyl-L-alanine amidase
FM050_15280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM050_15285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM050_15305	COG1335	isochorismatase
FM050_15320	COG0668	transmembrane transport
FM050_15325	COG4585	Histidine kinase
FM050_15325	COG2203	Gaf domain
FM050_15330	COG2197	response regulator
FM050_15335	COG1737	Transcriptional regulator
FM050_15340	COG0384	phenazine biosynthesis protein PhzF
FM050_15345	COG1064	alcohol dehydrogenase
FM050_15370	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FM050_15405	COG0517	IMP dehydrogenase activity
FM050_15405	COG1125	glycine betaine transport
FM050_15410	COG1174	glycine betaine transport
FM050_15445	COG1253	flavin adenine dinucleotide binding
FM050_15450	COG1012	belongs to the aldehyde dehydrogenase family
FM050_15455	COG5506	Protein of unknown function (DUF1694)
FM050_15470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FM050_15475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FM050_15480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FM050_15485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FM050_15490	COG0456	acetyltransferase
FM050_15495	COG3829	transcription factor binding
FM050_15500	COG1509	lysine 2,3-aminomutase activity
FM050_15535	COG4991	sh3 domain protein
FM050_15535	COG3064	Membrane
FM050_15535	COG0515	serine threonine protein kinase
FM050_15545	COG0671	phosphoesterase, PA-phosphatase related
FM050_15550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FM050_15555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM050_15635	COG0300	oxidoreductase activity
FM050_15655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FM050_15655	COG4499	WXG100 protein secretion system (Wss), protein YukC
FM050_15665	COG2814	Major facilitator Superfamily
FM050_15670	COG4841	protein insertion into membrane
FM050_15675	COG0372	Belongs to the citrate synthase family
FM050_15680	COG2079	MmgE PrpD family protein
FM050_15685	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FM050_15690	COG1960	acyl-CoA dehydrogenase activity
FM050_15695	COG2084	Dehydrogenase
FM050_15705	COG1280	lysine exporter protein (LysE YggA)
FM050_15710	COG1024	Enoyl-CoA hydratase
FM050_15725	COG0420	3'-5' exonuclease activity
FM050_15730	COG0419	ATPase involved in DNA repair
FM050_15745	COG2223	nitrite transmembrane transporter activity
FM050_15750	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_15755	COG1169	isochorismate synthase
FM050_15760	COG1021	2,3-dihydroxybenzoate-AMP ligase
FM050_15765	COG1535	isochorismatase
FM050_15765	COG3433	isochorismatase activity
FM050_15770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FM050_15775	COG3251	PFAM MbtH domain protein
FM050_15780	COG2814	Major facilitator Superfamily
FM050_15795	COG0776	regulation of translation
FM050_15805	COG2318	DinB family
FM050_15815	COG1115	amino acid carrier protein
FM050_15830	COG2329	Antibiotic biosynthesis monooxygenase
FM050_15835	COG1187	pseudouridine synthase activity
FM050_15840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FM050_15845	COG1136	(ABC) transporter
FM050_15860	COG0028	Belongs to the TPP enzyme family
FM050_15900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FM050_15925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_15960	COG1247	-acetyltransferase
FM050_15985	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FM050_15995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_16030	COG0583	DNA-binding transcription factor activity
FM050_16035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FM050_16055	COG0583	DNA-binding transcription factor activity
FM050_16060	COG2258	MOSC domain
FM050_16075	COG1132	(ABC) transporter
FM050_16080	COG1132	(ABC) transporter
FM050_16105	COG1396	sequence-specific DNA binding
FM050_16170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FM050_16175	COG1595	DNA-templated transcription, initiation
FM050_16195	COG1649	PFAM Uncharacterised BCR, COG1649
FM050_16220	COG2971	BadF BadG BcrA BcrD
FM050_16240	COG1846	Transcriptional regulator
FM050_16260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_16285	COG1309	transcriptional regulator
FM050_16310	COG3615	Tellurite resistance protein tehB
FM050_16310	COG0500	methyltransferase
FM050_16320	COG2226	methyltransferase
FM050_16325	COG3961	Belongs to the TPP enzyme family
FM050_16330	COG1846	Transcriptional regulator
FM050_16360	COG2195	Cleaves the N-terminal amino acid of tripeptides
FM050_16385	COG2002	toxin-antitoxin pair type II binding
FM050_16395	COG0730	response to heat
FM050_16400	COG0110	maltose O-acetyltransferase activity
FM050_16405	COG1686	Belongs to the peptidase S11 family
FM050_16420	COG2814	Major facilitator Superfamily
FM050_16490	COG0741	lytic transglycosylase activity
FM050_16495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_16500	COG2239	Acts as a magnesium transporter
FM050_16610	COG1396	sequence-specific DNA binding
FM050_16630	COG1309	transcriptional regulator
FM050_16635	COG0367	asparagine synthase
FM050_16665	COG1760	l-serine dehydratase
FM050_16670	COG1760	l-serine dehydratase
FM050_16675	COG0814	amino acid
FM050_16695	COG1533	DNA photolyase activity
FM050_16705	COG0076	glutamate decarboxylase activity
FM050_16740	COG0772	Belongs to the SEDS family
FM050_16745	COG2239	Acts as a magnesium transporter
FM050_16755	COG0768	penicillin binding
FM050_16760	COG1595	DNA-templated transcription, initiation
FM050_16770	COG0768	penicillin binding
FM050_16775	COG0768	penicillin binding
FM050_16790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_16805	COG1131	(ABC) transporter
FM050_16815	COG1309	transcriptional regulator
FM050_16830	COG1960	acyl-CoA dehydrogenase activity
FM050_16835	COG0439	Biotin carboxylase
FM050_16840	COG0511	ligase activity, forming carbon-carbon bonds
FM050_16845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FM050_16850	COG1024	Enoyl-CoA hydratase
FM050_16855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FM050_16860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FM050_16890	COG0572	uridine kinase
FM050_16910	COG1686	Belongs to the peptidase S11 family
FM050_16935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FM050_16950	COG3227	Zinc metalloprotease (Elastase)
FM050_16955	COG2207	Transcriptional regulator
FM050_17000	COG1942	4-Oxalocrotonate Tautomerase
FM050_17005	COG0583	DNA-binding transcription factor activity
FM050_17015	COG1131	(ABC) transporter
FM050_17045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_17050	COG2368	4-hydroxyphenylacetate
FM050_17075	COG2323	membrane
FM050_17080	COG0693	protein deglycase activity
FM050_17090	COG3386	PFAM SMP-30 Gluconolaconase
FM050_17100	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FM050_17105	COG3773	Cell wall hydrolase
FM050_17115	COG0745	RESPONSE REGULATOR receiver
FM050_17120	COG2205	protein histidine kinase activity
FM050_17125	COG0488	(ABC) transporter
FM050_17135	COG1136	(ABC) transporter
FM050_17140	COG0577	efflux transmembrane transporter activity
FM050_17160	COG0460	homoserine dehydrogenase
FM050_17165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_17175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FM050_17250	COG2124	cytochrome p450
FM050_17290	COG0561	phosphatase activity
FM050_17295	COG5002	protein histidine kinase activity
FM050_17300	COG0768	penicillin binding
FM050_17310	COG1819	glycosyl
FM050_17315	COG1794	racemase activity, acting on amino acids and derivatives
FM050_17340	COG2205	protein histidine kinase activity
FM050_17345	COG0582	viral genome integration into host DNA
FM050_17390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FM050_17410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FM050_17420	COG0745	RESPONSE REGULATOR receiver
FM050_17425	COG5002	protein histidine kinase activity
FM050_17430	COG0604	alcohol dehydrogenase
FM050_17435	COG0671	phosphoesterase, PA-phosphatase related
FM050_17440	COG0768	penicillin binding
FM050_17500	COG2814	Major facilitator Superfamily
FM050_17505	COG2814	Major facilitator Superfamily
FM050_17520	COG0584	glycerophosphoryl diester phosphodiesterase
FM050_17535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_17540	COG0697	spore germination
FM050_17575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FM050_17580	COG2223	nitrite transmembrane transporter activity
FM050_17595	COG0592	DNA-directed DNA polymerase activity
FM050_17625	COG3878	Protein conserved in bacteria
FM050_17690	COG0322	excinuclease ABC activity
FM050_17710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM050_17735	COG1011	Hydrolase
FM050_17740	COG0745	RESPONSE REGULATOR receiver
FM050_17745	COG5002	protein histidine kinase activity
FM050_17760	COG1136	(ABC) transporter
FM050_17765	COG0577	efflux transmembrane transporter activity
FM050_17770	COG1073	alpha beta
FM050_17775	COG0657	acetylesterase activity
FM050_17780	COG0076	glutamate decarboxylase activity
FM050_17795	COG1523	belongs to the glycosyl hydrolase 13 family
FM050_17800	COG3227	Zinc metalloprotease (Elastase)
FM050_17805	COG0737	Belongs to the 5'-nucleotidase family
FM050_17820	COG0201	protein transport
FM050_17825	COG0697	spore germination
FM050_17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_17865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_17880	COG2959	enzyme of heme biosynthesis
FM050_17920	COG1309	transcriptional regulator
FM050_17955	COG3284	Transcriptional regulator
FM050_17990	COG1959	2 iron, 2 sulfur cluster binding
FM050_18005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FM050_18010	COG0508	dehydrogenase complex catalyzes the overall conversion of
FM050_18015	COG0022	dehydrogenase e1 component
FM050_18020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FM050_18030	COG2814	Major facilitator Superfamily
FM050_18040	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_18045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FM050_18045	COG0456	acetyltransferase
FM050_18085	COG4176	ABC-type proline glycine betaine transport system permease component
FM050_18090	COG4175	Glycine betaine
FM050_18090	COG0517	IMP dehydrogenase activity
FM050_18120	COG2153	protein acetylation
FM050_18125	COG3397	chitin binding
FM050_18130	COG1819	glycosyl
FM050_18150	COG2205	protein histidine kinase activity
FM050_18155	COG2226	methyltransferase
FM050_18160	COG2315	Protein conserved in bacteria
FM050_18205	COG0456	acetyltransferase
FM050_18210	COG3973	AAA domain
FM050_18220	COG2105	PFAM AIG2 family protein
FM050_18225	COG0514	ATP-dependent DNA helicase (RecQ)
FM050_18260	COG4637	Psort location Cytoplasmic, score
FM050_18275	COG3397	chitin binding
FM050_18290	COG1162	GTPase activity
FM050_18295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FM050_18300	COG1115	amino acid carrier protein
FM050_18305	COG1012	belongs to the aldehyde dehydrogenase family
FM050_18310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FM050_18320	COG3938	Belongs to the proline racemase family
FM050_18325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FM050_18365	COG0586	Pfam SNARE associated Golgi protein
FM050_18375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FM050_18385	COG4166	transmembrane transport
FM050_18395	COG4948	Mandelate Racemase Muconate Lactonizing
FM050_18410	COG0667	Aldo Keto reductase
FM050_18455	COG3850	Histidine kinase
FM050_18455	COG5002	protein histidine kinase activity
FM050_18460	COG0745	RESPONSE REGULATOR receiver
FM050_18480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FM050_18490	COG1164	Oligoendopeptidase f
FM050_18495	COG1307	EDD domain protein, DegV family
FM050_18540	COG2814	Major facilitator Superfamily
FM050_18550	COG1664	Polymer-forming cytoskeletal
FM050_18555	COG0789	Transcriptional regulator
FM050_18560	COG4533	DNA binding
FM050_18565	COG0477	Major facilitator Superfamily
FM050_18565	COG2814	Major facilitator Superfamily
FM050_18590	COG2261	transglycosylase associated protein
FM050_18605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FM050_18640	COG0436	Aminotransferase
FM050_18645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FM050_18655	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FM050_18670	COG1131	(ABC) transporter
FM050_18720	COG0628	permease
FM050_18730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FM050_18735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FM050_18740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FM050_18770	COG2746	aminoglycoside 3-N-acetyltransferase activity
FM050_18790	COG0697	spore germination
FM050_18820	COG4912	Dna alkylation repair
FM050_18825	COG0346	lactoylglutathione lyase activity
FM050_18830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_18840	COG0861	Integral membrane protein TerC family
FM050_18850	COG1368	sulfuric ester hydrolase activity
FM050_18855	COG0488	(ABC) transporter
FM050_18870	COG2409	Drug exporters of the RND superfamily
FM050_18870	COG1033	growth of symbiont in host cell
FM050_18875	COG1309	transcriptional regulator
FM050_18890	COG0287	Prephenate dehydrogenase
FM050_18905	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FM050_18905	COG1605	Chorismate mutase
FM050_18950	COG3584	3D domain protein
FM050_18950	COG1388	LysM domain
FM050_18965	COG0277	FAD linked oxidase domain protein
FM050_18980	COG1879	ABC-type sugar transport system periplasmic component
FM050_18990	COG1172	Belongs to the binding-protein-dependent transport system permease family
FM050_19000	COG2390	Transcriptional regulator
FM050_19005	COG1070	Carbohydrate kinase
FM050_19030	COG2329	Antibiotic biosynthesis monooxygenase
FM050_19050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM050_19070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FM050_19075	COG4187	Peptidase family M20/M25/M40
FM050_19080	COG1414	Transcriptional regulator
FM050_19090	COG0833	amino acid
FM050_19105	COG3239	Fatty acid desaturase
FM050_19115	COG2720	vancomycin resistance protein
FM050_19120	COG1785	Belongs to the alkaline phosphatase family
FM050_19130	COG3655	Transcriptional regulator
FM050_19150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_19155	COG0346	lactoylglutathione lyase activity
FM050_19185	COG0714	Associated with various cellular activities
FM050_19230	COG0463	Glycosyl transferase, family 2
FM050_19250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FM050_19255	COG0753	catalase activity
FM050_19295	COG0714	Associated with various cellular activities
FM050_19385	COG0778	Nitroreductase
FM050_19390	COG1846	Transcriptional regulator
FM050_19415	COG3831	ATPase activity
FM050_19415	COG4884	unkown
FM050_19440	COG0590	tRNA wobble adenosine to inosine editing
FM050_19440	COG0037	tRNA processing
FM050_19445	COG0456	acetyltransferase
FM050_19460	COG0697	spore germination
FM050_19465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_19510	COG0730	response to heat
FM050_19520	COG0833	amino acid
FM050_19570	COG0768	penicillin binding
FM050_19605	COG1984	allophanate hydrolase subunit 2
FM050_19610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FM050_19615	COG1414	Transcriptional regulator
FM050_19625	COG3142	Participates in the control of copper homeostasis
FM050_19630	COG0640	Transcriptional regulator
FM050_19640	COG1960	acyl-CoA dehydrogenase activity
FM050_19655	COG3314	Sporulation integral membrane protein YlbJ
FM050_19665	COG0454	-acetyltransferase
FM050_19675	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FM050_19700	COG3848	Pyruvate phosphate dikinase
FM050_19700	COG0574	Belongs to the PEP-utilizing enzyme family
FM050_19720	COG1522	sequence-specific DNA binding
FM050_19725	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_19730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_19750	COG1063	alcohol dehydrogenase
FM050_19755	COG5002	protein histidine kinase activity
FM050_19780	COG2207	Transcriptional regulator
FM050_19800	COG0737	Belongs to the 5'-nucleotidase family
FM050_19805	COG2267	carboxylic ester hydrolase activity
FM050_19810	COG1335	isochorismatase
FM050_19835	COG2801	Transposase and inactivated derivatives
FM050_19840	COG0583	DNA-binding transcription factor activity
FM050_19855	COG2814	Major facilitator Superfamily
FM050_19890	COG0598	Magnesium transport protein CorA
FM050_19975	COG0657	acetylesterase activity
FM050_19980	COG0288	reversible hydration of carbon dioxide
FM050_19990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FM050_19995	COG5609	conserved protein (DUF2294)
FM050_20010	COG0456	acetyltransferase
FM050_20015	COG1575	Belongs to the MenA family. Type 1 subfamily
FM050_20025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_20035	COG0798	PFAM Bile acid sodium symporter
FM050_20040	COG0346	lactoylglutathione lyase activity
FM050_20045	COG0640	Transcriptional regulator
FM050_20050	COG2814	Major facilitator Superfamily
FM050_20055	COG1309	transcriptional regulator
FM050_20060	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_20065	COG1522	sequence-specific DNA binding
FM050_20085	COG0346	lactoylglutathione lyase activity
FM050_20180	COG2814	Major facilitator Superfamily
FM050_20195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FM050_20205	COG1690	Belongs to the RtcB family
FM050_20215	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FM050_20235	COG0577	efflux transmembrane transporter activity
FM050_20240	COG5002	protein histidine kinase activity
FM050_20240	COG3850	Histidine kinase
FM050_20250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_20280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FM050_20310	COG3831	ATPase activity
FM050_20330	COG3409	Peptidoglycan-binding domain 1 protein
FM050_20330	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_20410	COG5444	nuclease activity
FM050_20435	COG1876	peptidase activity
FM050_20440	COG2843	Capsule synthesis protein
FM050_20445	COG2801	Transposase and inactivated derivatives
FM050_20460	COG0477	Major facilitator Superfamily
FM050_20475	COG1846	Transcriptional regulator
FM050_20480	COG2814	Major facilitator Superfamily
FM050_20495	COG2031	fatty acid transporter
FM050_20505	COG2249	NAD(P)H dehydrogenase (quinone) activity
FM050_20560	COG1288	antiporter activity
FM050_20585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FM050_20595	COG1733	regulation of RNA biosynthetic process
FM050_20600	COG0778	Nitroreductase
FM050_20610	COG0469	pyruvate kinase activity
FM050_20630	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_20640	COG1131	(ABC) transporter
FM050_20665	COG1011	Hydrolase
FM050_20675	COG2365	Tyrosine phosphatase family
FM050_20710	COG0628	permease
FM050_20730	COG0500	methyltransferase
FM050_20740	COG0477	Major facilitator Superfamily
FM050_20770	COG1253	flavin adenine dinucleotide binding
FM050_20775	COG0789	Transcriptional regulator
FM050_20785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FM050_20815	COG0697	spore germination
FM050_20825	COG1357	PFAM Pentapeptide repeats (8 copies)
FM050_20830	COG3813	Protein conserved in bacteria
FM050_20835	COG2706	6-phosphogluconolactonase activity
FM050_20840	COG1070	Carbohydrate kinase
FM050_20850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FM050_20855	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FM050_20860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FM050_20865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FM050_20890	COG0840	transmembrane signaling receptor activity
FM050_20900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM050_20900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM050_20905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FM050_20905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FM050_20910	COG1733	regulation of RNA biosynthetic process
FM050_20925	COG0814	amino acid
FM050_20955	COG2188	Transcriptional regulator
FM050_20960	COG0673	inositol 2-dehydrogenase activity
FM050_20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_21000	COG0384	phenazine biosynthesis protein PhzF
FM050_21020	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_21025	COG2249	NAD(P)H dehydrogenase (quinone) activity
FM050_21030	COG1733	regulation of RNA biosynthetic process
FM050_21050	COG1191	sigma factor activity
FM050_21110	COG1151	hydroxylamine reductase activity
FM050_21175	COG1113	amino acid transport
FM050_21180	COG2814	Major facilitator Superfamily
FM050_21220	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FM050_21225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FM050_21235	COG1247	-acetyltransferase
FM050_21240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM050_21245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_21250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_21255	COG3739	integral membrane protein
FM050_21280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_21295	COG0583	DNA-binding transcription factor activity
FM050_21305	COG2890	protein-(glutamine-N5) methyltransferase activity
FM050_21320	COG1193	negative regulation of DNA recombination
FM050_21330	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FM050_21335	COG1164	Oligoendopeptidase f
FM050_21375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FM050_21405	COG0584	glycerophosphoryl diester phosphodiesterase
FM050_21415	COG0640	Transcriptional regulator
FM050_21420	COG0604	alcohol dehydrogenase
FM050_21430	COG0457	Tetratricopeptide repeat
FM050_21440	COG0385	Bile acid
FM050_21445	COG0277	FAD linked oxidase domain protein
FM050_21470	COG1183	phosphatidylcholine synthase activity
FM050_21480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_21480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM050_21485	COG1252	NADH dehydrogenase
FM050_21495	COG0823	Involved in the tonB-independent uptake of proteins
FM050_21500	COG3397	chitin binding
FM050_21510	COG0697	spore germination
FM050_21530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FM050_21540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FM050_21550	COG0457	Tetratricopeptide repeat
FM050_21590	COG1404	Belongs to the peptidase S8 family
FM050_21620	COG0488	(ABC) transporter
FM050_21645	COG3852	Histidine kinase
FM050_21655	COG1285	pathogenesis
FM050_21665	COG2514	catechol 2,3-dioxygenase activity
FM050_21670	COG2720	vancomycin resistance protein
FM050_21705	COG0716	FMN binding
FM050_21740	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_21750	COG0165	Argininosuccinate lyase
FM050_21765	COG4145	pantothenate transmembrane transporter activity
FM050_21775	COG1012	belongs to the aldehyde dehydrogenase family
FM050_21780	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_21790	COG1657	PFAM Prenyltransferase squalene oxidase
FM050_21795	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FM050_21800	COG2962	Rard protein
FM050_21805	COG3326	Membrane
FM050_21820	COG0489	protein tyrosine kinase activity
FM050_21830	COG0314	molybdopterin synthase activity
FM050_21835	COG0303	'Molybdopterin
FM050_21840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FM050_21845	COG2116	formate transmembrane transporter activity
FM050_21855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FM050_21860	COG5609	conserved protein (DUF2294)
FM050_21865	COG2427	Protein of unknown function (DUF1641)
FM050_21870	COG3383	formate dehydrogenase (NAD+) activity
FM050_21875	COG0697	spore germination
FM050_21890	COG0531	amino acid
FM050_21925	COG2226	methyltransferase
FM050_21930	COG4166	transmembrane transport
FM050_21935	COG4166	transmembrane transport
FM050_21940	COG4166	transmembrane transport
FM050_21945	COG1316	TRANSCRIPTIONal
FM050_21955	COG1595	DNA-templated transcription, initiation
FM050_21965	COG1131	(ABC) transporter
FM050_21985	COG0673	inositol 2-dehydrogenase activity
FM050_21990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FM050_21995	COG0187	DNA topoisomerase II activity
FM050_22000	COG1832	CoA-binding protein
FM050_22005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FM050_22010	COG0745	RESPONSE REGULATOR receiver
FM050_22020	COG1328	CTP reductase activity
FM050_22020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FM050_22030	COG4841	protein insertion into membrane
FM050_22035	COG0824	Thioesterase
FM050_22070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM050_22085	COG1132	(ABC) transporter
FM050_22095	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FM050_22125	COG2211	Major facilitator Superfamily
FM050_22135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FM050_22150	COG0183	Belongs to the thiolase family
FM050_22155	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_22160	COG1268	BioY protein
FM050_22165	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_22170	COG1396	sequence-specific DNA binding
FM050_22205	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FM050_22225	COG0830	nickel cation binding
FM050_22265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_22280	COG5002	protein histidine kinase activity
FM050_22285	COG0400	carboxylic ester hydrolase activity
FM050_22290	COG0346	lactoylglutathione lyase activity
FM050_22300	COG0069	glutamate synthase activity
FM050_22305	COG1902	pentaerythritol trinitrate reductase activity
FM050_22310	COG1329	Transcriptional regulator
FM050_22315	COG0010	Belongs to the arginase family
FM050_22340	COG2226	methyltransferase
FM050_22370	COG4846	Membrane protein involved in cytochrome C biogenesis
FM050_22375	COG0785	Cytochrome C biogenesis protein
FM050_22390	COG1473	amidohydrolase
FM050_22405	COG1131	(ABC) transporter
FM050_22420	COG0583	DNA-binding transcription factor activity
FM050_22430	COG1346	cytolysis
FM050_22445	COG0730	response to heat
FM050_22470	COG1132	(ABC) transporter
FM050_22475	COG1132	(ABC) transporter
FM050_22515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM050_22520	COG0737	Belongs to the 5'-nucleotidase family
FM050_22530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FM050_22550	COG1695	Transcriptional regulator
FM050_22560	COG0174	glutamine synthetase
FM050_22565	COG0789	Transcriptional regulator
FM050_22570	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FM050_22575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FM050_22580	COG2860	membrane
FM050_22585	COG0464	growth
FM050_22615	COG3584	3D domain protein
FM050_22615	COG1388	LysM domain
FM050_22625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FM050_22625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FM050_22625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FM050_22630	COG1105	Belongs to the carbohydrate kinase PfkB family
FM050_22635	COG1349	DNA-binding transcription factor activity
FM050_22640	COG1979	alcohol dehydrogenase
FM050_22645	COG2322	membrane
FM050_22655	COG1113	amino acid transport
FM050_22675	COG2116	formate transmembrane transporter activity
FM050_22690	COG2217	Heavy metal translocating P-type atpase
FM050_22695	COG2608	mercury ion transmembrane transporter activity
FM050_22700	COG1937	Protein conserved in bacteria
FM050_22710	COG2819	hydrolase of the alpha beta superfamily
FM050_22715	COG1120	ATPase activity
FM050_22720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_22725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_22730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM050_22740	COG2169	Transcriptional regulator
FM050_22745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FM050_22750	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FM050_22770	COG2267	carboxylic ester hydrolase activity
FM050_22775	COG3300	MHYT domain
FM050_22775	COG5001	Diguanylate cyclase
FM050_22795	COG1086	Polysaccharide biosynthesis protein
FM050_22815	COG1346	cytolysis
FM050_22825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FM050_22835	COG2188	Transcriptional regulator
FM050_22840	COG2723	6-phospho-beta-galactosidase activity
FM050_22845	COG0823	Involved in the tonB-independent uptake of proteins
FM050_22850	COG1404	Belongs to the peptidase S8 family
FM050_22855	COG3773	Cell wall hydrolase
FM050_22870	COG1368	sulfuric ester hydrolase activity
FM050_22875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FM050_22900	COG4550	Control of competence regulator ComK, YlbF/YmcA
FM050_22910	COG1013	pyruvate-flavodoxin oxidoreductase activity
FM050_22915	COG0674	pyruvate-flavodoxin oxidoreductase activity
FM050_22915	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FM050_22925	COG2359	stage V sporulation protein S
FM050_22930	COG1692	metallophosphoesterase
FM050_22950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FM050_22955	COG1426	Protein conserved in bacteria
FM050_22970	COG0300	oxidoreductase activity
FM050_22975	COG0612	Peptidase, M16
FM050_22980	COG0612	Peptidase, M16
FM050_22985	COG1079	Belongs to the binding-protein-dependent transport system permease family
FM050_22990	COG4603	Belongs to the binding-protein-dependent transport system permease family
FM050_22995	COG3845	ABC transporter
FM050_23000	COG1744	ABC transporter substrate-binding protein PnrA-like
FM050_23005	COG2188	Transcriptional regulator
FM050_23025	COG0740	serine-type endopeptidase activity
FM050_23035	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FM050_23045	COG0527	aspartate kinase activity
FM050_23050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FM050_23055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FM050_23060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FM050_23065	COG1873	PFAM PRC-barrel domain
FM050_23070	COG0612	Peptidase, M16
FM050_23075	COG0726	polysaccharide deacetylase
FM050_23090	COG0196	riboflavin kinase activity
FM050_23100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FM050_23105	COG1550	Protein conserved in bacteria
FM050_23115	COG1358	cellular component organization or biogenesis
FM050_23120	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FM050_23125	COG0195	Participates in both transcription termination and antitermination
FM050_23145	COG0750	zinc metalloprotease
FM050_23155	COG4589	Belongs to the CDS family
FM050_23205	COG4974	Belongs to the 'phage' integrase family
FM050_23215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FM050_23220	COG0758	DNA mediated transformation
FM050_23225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FM050_23265	COG1837	Belongs to the UPF0109 family
FM050_23275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FM050_23285	COG0552	protein localization to endoplasmic reticulum
FM050_23290	COG1196	nuclear chromosome segregation
FM050_23300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FM050_23305	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_23310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FM050_23325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FM050_23330	COG1461	Dihydroxyacetone kinase
FM050_23335	COG1302	Protein conserved in bacteria
FM050_23350	COG1564	THIamine pyrophosphokinase
FM050_23355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FM050_23365	COG2815	serine threonine protein kinase
FM050_23365	COG0515	serine threonine protein kinase
FM050_23370	COG0631	protein serine/threonine phosphatase activity
FM050_23380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FM050_23380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FM050_23395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FM050_23400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FM050_23420	COG1561	YicC-like family, N-terminal region
FM050_23425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FM050_23435	COG0006	proline dipeptidase activity
FM050_23450	COG3069	C4-dicarboxylate transmembrane transporter activity
FM050_23510	COG0564	pseudouridine synthase activity
FM050_23530	COG3599	regulation of cell shape
FM050_23535	COG2302	S4 RNA-binding domain
FM050_23540	COG0762	integral membrane protein
FM050_23550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FM050_23560	COG1873	PFAM PRC-barrel domain
FM050_23565	COG1191	sigma factor activity
FM050_23570	COG1191	sigma factor activity
FM050_23580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FM050_23585	COG0849	cell division
FM050_23605	COG0772	Belongs to the SEDS family
FM050_23625	COG0768	penicillin binding
FM050_23630	COG0768	penicillin binding
FM050_23650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FM050_23670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FM050_23675	COG1399	metal-binding, possibly nucleic acid-binding protein
FM050_23715	COG4824	toxin secretion phage lysis holin
FM050_23790	COG0740	serine-type endopeptidase activity
FM050_23850	COG0582	viral genome integration into host DNA
FM050_23905	COG2002	toxin-antitoxin pair type II binding
FM050_23915	COG1484	DNA-dependent DNA replication
FM050_23930	COG3646	Phage regulatory protein
FM050_23940	COG1396	sequence-specific DNA binding
FM050_23985	COG1459	type II secretion system
FM050_23990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FM050_24045	COG1410	methionine synthase
FM050_24045	COG0646	methionine synthase
FM050_24050	COG0646	methionine synthase
FM050_24050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FM050_24055	COG0626	cystathionine gamma-synthase activity
FM050_24060	COG0626	cystathionine gamma-synthase activity
FM050_24080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_24090	COG1940	carbohydrate kinase activity
FM050_24095	COG4483	Protein conserved in bacteria
FM050_24100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FM050_24105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FM050_24110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FM050_24115	COG0704	Plays a role in the regulation of phosphate uptake
FM050_24125	COG0573	inorganic phosphate transmembrane transporter activity
FM050_24130	COG0573	inorganic phosphate transmembrane transporter activity
FM050_24135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FM050_24145	COG0768	penicillin binding
FM050_24150	COG0477	Major facilitator Superfamily
FM050_24155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FM050_24165	COG5521	maltodextrose utilization protein MalA
FM050_24180	COG0735	belongs to the Fur family
FM050_24185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FM050_24190	COG1121	(ABC) transporter
FM050_24195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_24225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FM050_24230	COG2384	SAM-dependent methyltransferase
FM050_24240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FM050_24245	COG0358	DNA primase activity
FM050_24255	COG0517	IMP dehydrogenase activity
FM050_24270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FM050_24275	COG0295	cytidine deaminase activity
FM050_24280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FM050_24290	COG1480	7TM receptor with intracellular HD hydrolase
FM050_24295	COG1702	phosphate starvation-inducible protein PhoH
FM050_24315	COG1610	YqeY-like protein
FM050_24320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FM050_24325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FM050_24330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FM050_24360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM050_24365	COG1733	regulation of RNA biosynthetic process
FM050_24390	COG1466	dna polymerase III delta subunit
FM050_24400	COG0658	competence protein
FM050_24400	COG2333	competence protein COMEC
FM050_24405	COG2131	deaminase
FM050_24410	COG1555	photosystem II stabilization
FM050_24410	COG1596	polysaccharide export
FM050_24415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FM050_24420	COG2226	methyltransferase
FM050_24425	COG0799	negative regulation of ribosome biogenesis
FM050_24430	COG1713	HD superfamily hydrolase involved in NAD metabolism
FM050_24440	COG1534	Rna-binding protein
FM050_24450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FM050_24455	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FM050_24490	COG0778	Nitroreductase
FM050_24495	COG2357	RelA SpoT domain protein
FM050_24505	COG1785	Belongs to the alkaline phosphatase family
FM050_24515	COG2267	carboxylic ester hydrolase activity
FM050_24560	COG3186	Phenylalanine-4-hydroxylase
FM050_24570	COG2514	catechol 2,3-dioxygenase activity
FM050_24575	COG2259	Doxx family
FM050_24615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM050_24630	COG2801	Transposase and inactivated derivatives
FM050_24640	COG1454	alcohol dehydrogenase
FM050_24640	COG1012	belongs to the aldehyde dehydrogenase family
FM050_24645	COG0626	cystathionine gamma-synthase activity
FM050_24650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FM050_24725	COG1388	LysM domain
FM050_24725	COG3409	Peptidoglycan-binding domain 1 protein
FM050_24725	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_24740	COG3547	Transposase (IS116 IS110 IS902 family)
FM050_24835	COG3728	DNA packaging
FM050_24835	COG5484	DNA packaging
FM050_24895	COG3331	DNA recombination
FM050_25005	COG1396	sequence-specific DNA binding
FM050_25015	COG0582	viral genome integration into host DNA
FM050_25025	COG0826	peptidase U32
FM050_25030	COG0826	peptidase U32
FM050_25035	COG4122	O-methyltransferase activity
FM050_25040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FM050_25070	COG0628	permease
FM050_25090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FM050_25105	COG1104	cysteine desulfurase activity
FM050_25110	COG1959	2 iron, 2 sulfur cluster binding
FM050_25115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FM050_25130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FM050_25155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FM050_25165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FM050_25165	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FM050_25170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FM050_25175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM050_25175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM050_25185	COG2244	polysaccharide biosynthetic process
FM050_25190	COG2323	membrane
FM050_25200	COG1862	Preprotein translocase
FM050_25230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FM050_25260	COG0157	Belongs to the NadC ModD family
FM050_25265	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FM050_25270	COG1104	cysteine desulfurase activity
FM050_25275	COG1827	regulation of RNA biosynthetic process
FM050_25280	COG2258	MOSC domain
FM050_25285	COG0077	Prephenate dehydratase
FM050_25290	COG0577	efflux transmembrane transporter activity
FM050_25295	COG0577	efflux transmembrane transporter activity
FM050_25300	COG1136	(ABC) transporter
FM050_25305	COG5002	protein histidine kinase activity
FM050_25310	COG0745	RESPONSE REGULATOR receiver
FM050_25320	COG3290	protein histidine kinase activity
FM050_25335	COG1530	ribonuclease E activity
FM050_25340	COG1994	Peptidase M50
FM050_25345	COG0739	heme binding
FM050_25350	COG2894	cell division
FM050_25370	COG1077	Cell shape determining protein MreB Mrl
FM050_25395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FM050_25420	COG2003	Belongs to the UPF0758 family
FM050_25450	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_25565	COG1595	DNA-templated transcription, initiation
FM050_25575	COG3331	DNA recombination
FM050_25655	COG3646	Phage regulatory protein
FM050_25670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FM050_25690	COG0285	dihydrofolate synthase activity
FM050_25705	COG1388	LysM domain
FM050_25715	COG0113	porphobilinogen synthase activity
FM050_25720	COG1587	Uroporphyrinogen-III synthase
FM050_25730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FM050_25740	COG1846	Transcriptional regulator
FM050_25745	COG1764	response to oxidative stress
FM050_25760	COG1067	ATP-dependent peptidase activity
FM050_25760	COG0470	DNA polymerase III
FM050_25890	COG0622	Phosphoesterase
FM050_25905	COG5401	PFAM Sporulation and spore germination
FM050_25920	COG2197	response regulator
FM050_25925	COG2233	PERMEase
FM050_25930	COG0402	S-adenosylhomocysteine deaminase activity
FM050_25935	COG1983	PspC domain protein
FM050_25940	COG1396	sequence-specific DNA binding
FM050_25945	COG0697	spore germination
FM050_25955	COG1959	2 iron, 2 sulfur cluster binding
FM050_25960	COG1668	transmembrane transport
FM050_25965	COG4152	abc transporter atp-binding protein
FM050_25970	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FM050_25975	COG1360	Flagellar Motor Protein
FM050_25980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FM050_25985	COG1876	peptidase activity
FM050_25990	COG0824	Thioesterase
FM050_25995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FM050_26000	COG1053	succinate dehydrogenase
FM050_26005	COG2009	succinate dehydrogenase
FM050_26010	COG1719	4-vinyl reductase, 4VR
FM050_26020	COG3118	belongs to the thioredoxin family
FM050_26025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FM050_26030	COG2086	electron transfer activity
FM050_26035	COG1024	Enoyl-CoA hydratase
FM050_26040	COG1309	transcriptional regulator
FM050_26045	COG0318	PFAM AMP-dependent synthetase and ligase
FM050_26070	COG2318	DinB family
FM050_26095	COG1131	(ABC) transporter
FM050_26100	COG2205	protein histidine kinase activity
FM050_26105	COG0745	RESPONSE REGULATOR receiver
FM050_26110	COG4895	conserved protein (DUF2196)
FM050_26115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FM050_26125	COG4509	Sortase family
FM050_26130	COG1120	ATPase activity
FM050_26145	COG5386	Cell surface protein
FM050_26155	COG5386	Cell surface protein
FM050_26160	COG1114	Component of the transport system for branched-chain amino acids
FM050_26165	COG1187	pseudouridine synthase activity
FM050_26175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FM050_26175	COG1796	DNA polymerase
FM050_26180	COG1286	toxin biosynthetic process
FM050_26225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FM050_26235	COG1418	mRNA catabolic process
FM050_26255	COG2814	Major facilitator Superfamily
FM050_26260	COG1566	PFAM secretion protein HlyD family protein
FM050_26265	COG1309	transcriptional regulator
FM050_26270	COG1363	Peptidase, m42
FM050_26300	COG2801	Transposase and inactivated derivatives
FM050_26305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FM050_26320	COG1484	DNA-dependent DNA replication
FM050_26325	COG3611	Membrane attachment protein
FM050_26335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FM050_26340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FM050_26350	COG1971	Probably functions as a manganese efflux pump
FM050_26360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM050_26360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM050_26365	COG5002	protein histidine kinase activity
FM050_26370	COG0745	RESPONSE REGULATOR receiver
FM050_26390	COG0538	isocitrate dehydrogenase activity
FM050_26395	COG0372	Belongs to the citrate synthase family
FM050_26410	COG0628	permease
FM050_26415	COG3030	protein affecting phage T7 exclusion by the F plasmid
FM050_26440	COG1725	Transcriptional regulator
FM050_26445	COG0281	malic enzyme
FM050_26450	COG0587	DNA-directed DNA polymerase activity
FM050_26465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FM050_26480	COG4109	DRTGG domain
FM050_26490	COG0006	proline dipeptidase activity
FM050_26540	COG0662	Cupin 2, conserved barrel domain protein
FM050_26555	COG1028	Short-chain dehydrogenase reductase Sdr
FM050_26560	COG0589	response to stress
FM050_26600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_26625	COG0827	DNA restriction-modification system
FM050_26630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FM050_26635	COG3874	Sporulation protein YtfJ
FM050_26650	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FM050_26660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FM050_26675	COG1104	cysteine desulfurase activity
FM050_26685	COG0583	DNA-binding transcription factor activity
FM050_26690	COG0697	spore germination
FM050_26695	COG1309	transcriptional regulator
FM050_26700	COG1956	GAF domain-containing protein
FM050_26705	COG0626	cystathionine gamma-synthase activity
FM050_26750	COG1595	DNA-templated transcription, initiation
FM050_26760	COG0110	maltose O-acetyltransferase activity
FM050_26765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FM050_26770	COG0454	-acetyltransferase
FM050_26775	COG0517	IMP dehydrogenase activity
FM050_26780	COG0123	including yeast histone deacetylase and acetoin utilization protein
FM050_26795	COG0745	RESPONSE REGULATOR receiver
FM050_26805	COG0666	response to abiotic stimulus
FM050_26810	COG0745	RESPONSE REGULATOR receiver
FM050_26810	COG2972	Histidine kinase
FM050_26830	COG3279	Response regulator of the LytR AlgR family
FM050_26865	COG1609	Transcriptional regulator
FM050_26870	COG1605	Chorismate mutase
FM050_26870	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FM050_26875	COG4851	CamS sex pheromone cAM373 precursor
FM050_26880	COG3118	belongs to the thioredoxin family
FM050_26890	COG2309	aminopeptidase activity
FM050_26905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_26920	COG1674	ftsk spoiiie
FM050_26935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM050_26945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM050_26950	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FM050_26955	COG1363	Peptidase, m42
FM050_26965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_26980	COG0510	thiamine kinase activity
FM050_26985	COG1523	belongs to the glycosyl hydrolase 13 family
FM050_26995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FM050_27000	COG1349	DNA-binding transcription factor activity
FM050_27005	COG1187	pseudouridine synthase activity
FM050_27010	COG2244	polysaccharide biosynthetic process
FM050_27015	COG2081	HI0933 family
FM050_27020	COG2814	Major facilitator Superfamily
FM050_27030	COG3832	glyoxalase III activity
FM050_27055	COG1329	Transcriptional regulator
FM050_27080	COG0314	molybdopterin synthase activity
FM050_27085	COG1763	Mo-molybdopterin cofactor biosynthetic process
FM050_27090	COG0303	'Molybdopterin
FM050_27100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FM050_27105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FM050_27130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM050_27140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FM050_27185	COG2814	Major facilitator Superfamily
FM050_27190	COG0475	glutathione-regulated potassium exporter activity
FM050_27195	COG0490	domain, Protein
FM050_27200	COG0582	viral genome integration into host DNA
FM050_27215	COG1136	(ABC) transporter
FM050_27235	COG1242	4 iron, 4 sulfur cluster binding
FM050_27240	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FM050_27245	COG1794	racemase activity, acting on amino acids and derivatives
FM050_27270	COG2267	carboxylic ester hydrolase activity
FM050_27275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FM050_27280	COG0671	phosphoesterase, PA-phosphatase related
FM050_27285	COG0438	transferase activity, transferring glycosyl groups
FM050_27310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_27350	COG0546	phosphoglycolate phosphatase activity
FM050_27355	COG1349	DNA-binding transcription factor activity
FM050_27370	COG5002	protein histidine kinase activity
FM050_27375	COG3852	Histidine kinase
FM050_27380	COG2267	carboxylic ester hydrolase activity
FM050_27385	COG1368	sulfuric ester hydrolase activity
FM050_27410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FM050_27415	COG1116	anion transmembrane transporter activity
FM050_27420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FM050_27445	COG0494	nUDIX hydrolase
FM050_27475	COG1854	S-ribosylhomocysteine lyase activity
FM050_27490	COG1271	oxidase subunit
FM050_27495	COG1294	oxidase, subunit
FM050_27505	COG2801	Transposase and inactivated derivatives
FM050_27520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_27540	COG1842	Phage shock protein A
FM050_27575	COG5002	protein histidine kinase activity
FM050_27580	COG0745	RESPONSE REGULATOR receiver
FM050_27605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FM050_27610	COG1597	lipid kinase activity
FM050_27635	COG0586	Pfam SNARE associated Golgi protein
FM050_27645	COG0577	efflux transmembrane transporter activity
FM050_27650	COG1136	(ABC) transporter
FM050_27655	COG3708	Transcriptional regulator
FM050_27655	COG2207	Transcriptional regulator
FM050_27665	COG5658	integral membrane protein
FM050_27670	COG0640	Transcriptional regulator
FM050_27675	COG0745	RESPONSE REGULATOR receiver
FM050_27680	COG2205	protein histidine kinase activity
FM050_27685	COG0577	efflux transmembrane transporter activity
FM050_27690	COG0577	efflux transmembrane transporter activity
FM050_27695	COG1136	(ABC) transporter
FM050_27700	COG0577	efflux transmembrane transporter activity
FM050_27730	COG2188	Transcriptional regulator
FM050_27750	COG3964	amidohydrolase
FM050_27770	COG4948	Mandelate Racemase Muconate Lactonizing
FM050_27800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FM050_27805	COG0596	Alpha beta hydrolase
FM050_27815	COG1169	isochorismate synthase
FM050_27820	COG1575	Belongs to the MenA family. Type 1 subfamily
FM050_27825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FM050_27845	COG0058	SHG alpha-glucan phosphorylase activity
FM050_27855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FM050_27980	COG0544	peptidyl-prolyl cis-trans isomerase activity
FM050_28015	COG1285	pathogenesis
FM050_28020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FM050_28040	COG2155	Conserved Protein
FM050_28045	COG1098	S1 RNA binding domain
FM050_28050	COG0436	Aminotransferase
FM050_28060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FM050_28065	COG2267	carboxylic ester hydrolase activity
FM050_28075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FM050_28090	COG5018	Exonuclease
FM050_28095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FM050_28120	COG2050	protein possibly involved in aromatic compounds catabolism
FM050_28130	COG1268	BioY protein
FM050_28135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FM050_28140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FM050_28155	COG3584	3D domain protein
FM050_28170	COG1252	NADH dehydrogenase
FM050_28200	COG1683	Conserved Protein
FM050_28255	COG1388	LysM domain
FM050_28255	COG3409	Peptidoglycan-binding domain 1 protein
FM050_28255	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_28260	COG4824	toxin secretion phage lysis holin
FM050_28395	COG1191	sigma factor activity
FM050_28420	COG3646	Phage regulatory protein
FM050_28420	COG3645	SOS response
FM050_28435	COG3620	sequence-specific DNA binding
FM050_28480	COG0316	Belongs to the HesB IscA family
FM050_28495	COG1252	NADH dehydrogenase
FM050_28510	COG0390	transport system, permease component
FM050_28515	COG2824	Alkylphosphonate utilization operon protein PhnA
FM050_28560	COG4837	Protein of unknown function (DUF1462)
FM050_28565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FM050_28575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FM050_28580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FM050_28600	COG1358	cellular component organization or biogenesis
FM050_28615	COG2249	NAD(P)H dehydrogenase (quinone) activity
FM050_28620	COG0647	UMP catabolic process
FM050_28630	COG2445	Protein of unknown function DUF86
FM050_28635	COG1494	fructose-1,6-bisphosphatase
FM050_28655	COG4470	Protein conserved in bacteria
FM050_28665	COG0789	Transcriptional regulator
FM050_28670	COG4377	Putative membrane peptidase family (DUF2324)
FM050_28695	COG0739	heme binding
FM050_28705	COG3377	Domain of unknown function (DUF1805)
FM050_28710	COG0737	Belongs to the 5'-nucleotidase family
FM050_28720	COG2801	Transposase and inactivated derivatives
FM050_28750	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_28890	COG1396	sequence-specific DNA binding
FM050_28960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FM050_28965	COG0582	viral genome integration into host DNA
FM050_28970	COG0719	Fe-S assembly protein
FM050_28975	COG0822	iron-sulfur transferase activity
FM050_28980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FM050_28985	COG0719	Fe-S assembly protein
FM050_28990	COG0396	ATPase activity
FM050_28995	COG1464	Belongs to the NlpA lipoprotein family
FM050_29000	COG1464	Belongs to the NlpA lipoprotein family
FM050_29005	COG2011	ABC-type metal ion transport system permease component
FM050_29020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM050_29025	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FM050_29035	COG1393	Belongs to the ArsC family
FM050_29055	COG0039	L-malate dehydrogenase activity
FM050_29075	COG1309	transcriptional regulator
FM050_29080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FM050_29085	COG1960	acyl-CoA dehydrogenase activity
FM050_29090	COG0183	Belongs to the thiolase family
FM050_29095	COG1250	3-hydroxyacyl-CoA dehydrogenase
FM050_29095	COG1024	Enoyl-CoA hydratase
FM050_29105	COG1686	Belongs to the peptidase S11 family
FM050_29120	COG0011	TIGRFAM Protein of
FM050_29125	COG0840	transmembrane signaling receptor activity
FM050_29140	COG2814	Major facilitator Superfamily
FM050_29145	COG0531	amino acid
FM050_29165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FM050_29205	COG0586	Pfam SNARE associated Golgi protein
FM050_29215	COG1376	ErfK ybiS ycfS ynhG family protein
FM050_29220	COG0745	RESPONSE REGULATOR receiver
FM050_29225	COG5002	protein histidine kinase activity
FM050_29255	COG0840	transmembrane signaling receptor activity
FM050_29260	COG2151	metal-sulfur cluster biosynthetic enzyme
FM050_29280	COG4974	Belongs to the 'phage' integrase family
FM050_29305	COG3227	Zinc metalloprotease (Elastase)
FM050_29325	COG0586	Pfam SNARE associated Golgi protein
FM050_29330	COG0475	glutathione-regulated potassium exporter activity
FM050_29335	COG0490	domain, Protein
FM050_29345	COG1115	amino acid carrier protein
FM050_29350	COG0783	Belongs to the Dps family
FM050_29370	COG1611	Belongs to the LOG family
FM050_29380	COG1528	Iron-storage protein
FM050_29385	COG2311	Membrane
FM050_29390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM050_29395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM050_29400	COG1115	amino acid carrier protein
FM050_29405	COG1115	amino acid carrier protein
FM050_29410	COG2910	NAD(P)H-binding
FM050_29425	COG0656	L-ascorbic acid biosynthetic process
FM050_29430	COG2814	Major facilitator Superfamily
FM050_29435	COG1733	regulation of RNA biosynthetic process
FM050_29445	COG1252	NADH dehydrogenase
FM050_29500	COG0488	(ABC) transporter
FM050_29505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FM050_29550	COG0745	RESPONSE REGULATOR receiver
FM050_29610	COG0557	exoribonuclease II activity
FM050_29615	COG1647	Serine aminopeptidase, S33
FM050_29620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FM050_29625	COG1346	cytolysis
FM050_29660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FM050_29675	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FM050_29700	COG3409	Peptidoglycan-binding domain 1 protein
FM050_29700	COG5632	N-Acetylmuramoyl-L-alanine amidase
FM050_29700	COG1388	LysM domain
FM050_29705	COG4824	toxin secretion phage lysis holin
FM050_29840	COG3331	DNA recombination
FM050_29925	COG3646	Phage regulatory protein
FM050_29950	COG0582	viral genome integration into host DNA
FM050_29975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FM050_29990	COG2323	membrane
FM050_30000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FM050_30010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FM050_30020	COG1051	belongs to the nudix hydrolase family
FM050_30030	COG0492	ferredoxin-NADP+ reductase activity
FM050_30035	COG0457	Tetratricopeptide repeat
FM050_30040	COG0110	maltose O-acetyltransferase activity
FM050_30060	COG1950	PFAM Membrane protein of
FM050_30070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FM050_30075	COG0556	nucleotide-excision repair
FM050_30090	COG0789	Transcriptional regulator
FM050_30110	COG0583	DNA-binding transcription factor activity
FM050_30120	COG0655	NAD(P)H dehydrogenase (quinone) activity
FM050_30125	COG0488	(ABC) transporter
FM050_30135	COG1132	(ABC) transporter
FM050_30140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FM050_30145	COG0793	Belongs to the peptidase S41A family
FM050_30145	COG3409	Peptidoglycan-binding domain 1 protein
FM050_30150	COG2177	Part of the ABC transporter FtsEX involved in
FM050_30155	COG2884	Cell division ATP-binding protein ftsE
FM050_30185	COG1131	(ABC) transporter
FM050_30215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FM050_30220	COG1278	Cold shock
FM050_30225	COG1040	competence protein
FM050_30230	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FM050_30235	COG0791	NLP P60 protein
FM050_30235	COG1388	LysM domain
FM050_30240	COG1733	regulation of RNA biosynthetic process
FM050_30245	COG1307	EDD domain protein, DegV family
FM050_30250	COG1739	Uncharacterized protein family UPF0029
FM050_30255	COG1316	TRANSCRIPTIONal
FM050_30260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FM050_30265	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FM050_30270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FM050_30280	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FM050_30280	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FM050_30300	COG1486	melibiose metabolic process
FM050_30305	COG1447	Phosphotransferase system cellobiose-specific component IIA
FM050_30310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FM050_30320	COG1447	Phosphotransferase system cellobiose-specific component IIA
FM050_30330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FM050_30335	COG1301	dicarboxylic acid transport
FM050_30350	COG1511	domain protein
FM050_30355	COG0583	DNA-binding transcription factor activity
FM050_30360	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FM050_30365	COG1271	oxidase subunit
FM050_30370	COG1294	oxidase, subunit
FM050_30375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FM050_30385	COG1620	l-lactate permease
FM050_30400	COG2389	metal-binding protein
FM050_30415	COG1368	sulfuric ester hydrolase activity
FM050_30440	COG0791	NLP P60 protein
FM050_30440	COG1388	LysM domain
FM050_30445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FM050_30460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FM050_30470	COG3584	3D domain protein
FM050_30470	COG1388	LysM domain
FM050_30495	COG4715	Zinc finger, swim domain protein
FM050_30500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FM050_30540	COG0577	efflux transmembrane transporter activity
FM050_30545	COG1136	(ABC) transporter
FM050_30570	COG5002	protein histidine kinase activity
FM050_30575	COG0745	RESPONSE REGULATOR receiver
FM050_30585	COG1316	TRANSCRIPTIONal
FM050_30590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FM050_30595	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FM050_30600	COG1215	transferase activity, transferring glycosyl groups
FM050_30605	COG0463	Glycosyl transferase, family 2
FM050_30610	COG0438	transferase activity, transferring glycosyl groups
FM050_30620	COG1216	Glycosyl transferase, family 2
FM050_30635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FM050_30640	COG4464	protein tyrosine phosphatase activity
FM050_30645	COG0489	protein tyrosine kinase activity
FM050_30650	COG3944	biosynthesis protein
FM050_30655	COG0489	protein tyrosine kinase activity
FM050_30670	COG1609	Transcriptional regulator
FM050_30680	COG0739	heme binding
FM050_30695	COG3279	Response regulator of the LytR AlgR family
FM050_30700	COG2385	sporulation resulting in formation of a cellular spore
FM050_30715	COG4836	Membrane
FM050_30720	COG1007	ATP synthesis coupled electron transport
FM050_30725	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM050_30730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FM050_30740	COG0839	Belongs to the complex I subunit 6 family
FM050_30760	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM050_30775	COG3300	MHYT domain
FM050_30775	COG5001	Diguanylate cyclase
FM050_30825	COG0356	it plays a direct role in the translocation of protons across the membrane
FM050_30860	COG0698	ribose 5-phosphate isomerase
FM050_30875	COG2259	Doxx family
FM050_30880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FM050_30895	COG0009	L-threonylcarbamoyladenylate synthase
FM050_30930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FM050_30935	COG1494	fructose-1,6-bisphosphatase
FM050_30955	COG4821	SIS domain
FM050_30965	COG3343	RNA polymerase activity
FM050_30975	COG1960	acyl-CoA dehydrogenase activity
FM050_30980	COG1960	acyl-CoA dehydrogenase activity
FM050_30985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FM050_30990	COG0183	Belongs to the thiolase family
FM050_30995	COG0247	lactate metabolic process
FM050_30995	COG2181	nitrate reductase activity
FM050_31000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FM050_31010	COG3300	MHYT domain
FM050_31010	COG5001	Diguanylate cyclase
FM050_31025	COG3227	Zinc metalloprotease (Elastase)
FM050_31030	COG2197	response regulator
FM050_31035	COG4585	Histidine kinase
FM050_31040	COG0842	Transport permease protein
FM050_31045	COG1131	(ABC) transporter
FM050_31050	COG0024	Methionine aminopeptidase
FM050_31065	COG2234	aminopeptidase activity
FM050_31085	COG1595	DNA-templated transcription, initiation
FM050_31095	COG4506	Protein conserved in bacteria
FM050_31100	COG1619	proteins homologs of microcin C7 resistance protein MccF
FM050_31125	COG2814	Major facilitator Superfamily
FM050_31130	COG0789	Transcriptional regulator
FM050_31135	COG0584	glycerophosphoryl diester phosphodiesterase
FM050_31140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FM050_31150	COG1994	Peptidase M50
FM050_31160	COG1078	dGTPase activity
FM050_31165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FM050_31175	COG2801	Transposase and inactivated derivatives
FM050_31180	COG1120	ATPase activity
FM050_31185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_31190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM050_31210	COG0280	phosphate acetyltransferase
FM050_31225	COG3773	Cell wall hydrolase
FM050_31235	COG2363	Small membrane protein
FM050_31245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FM050_31250	COG2233	PERMEase
FM050_31255	COG0561	phosphatase activity
FM050_31260	COG2814	Major facilitator Superfamily
FM050_31275	COG1131	(ABC) transporter
FM050_31280	COG2755	lipolytic protein G-D-S-L family
FM050_31285	COG1609	Transcriptional regulator
FM050_31295	COG0460	homoserine dehydrogenase
FM050_31305	COG2873	o-acetylhomoserine
FM050_31315	COG1011	Hydrolase
FM050_31320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FM050_31330	COG2197	response regulator
FM050_31335	COG4585	Histidine kinase
FM050_31335	COG2203	Gaf domain
FM050_31340	COG0351	phosphomethylpyrimidine kinase
FM050_31345	COG3706	GGDEF domain
FM050_31350	COG2879	small protein
FM050_31355	COG1966	Carbon starvation protein
FM050_31360	COG3279	Response regulator of the LytR AlgR family
FM050_31365	COG0477	Major facilitator Superfamily
FM050_31380	COG0438	transferase activity, transferring glycosyl groups
FM050_31395	COG0840	transmembrane signaling receptor activity
FM050_31405	COG1607	acyl-coa hydrolase
FM050_31410	COG1216	Glycosyl transferase, family 2
FM050_31425	COG1216	Glycosyl transferase, family 2
FM050_31435	COG4485	Bacterial membrane protein, YfhO
FM050_31440	COG0463	Glycosyl transferase, family 2
FM050_31445	COG0488	(ABC) transporter
FM050_31450	COG1309	transcriptional regulator
FM050_31455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM050_31465	COG0628	permease
FM050_31485	COG3275	phosphorelay sensor kinase activity
FM050_31490	COG2814	Major facilitator Superfamily
FM050_31495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FM050_31540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FM050_31545	COG1272	protein, Hemolysin III
FM050_31580	COG5002	protein histidine kinase activity
FM050_31595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FM050_31600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FM050_31605	COG4853	Protein conserved in bacteria
FM050_31615	COG5002	protein histidine kinase activity
FM050_31620	COG0745	RESPONSE REGULATOR receiver
FM050_31650	COG0305	Participates in initiation and elongation during chromosome replication
FM050_31660	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FM050_31665	COG4241	membrane
FM050_31685	COG0012	GTP binding
FM050_31690	COG4481	Protein conserved in bacteria
FM050_31695	COG0668	transmembrane transport
FM050_31705	COG1475	DNA binding
FM050_31710	COG1192	Involved in chromosome partitioning
FM050_31735	COG1847	R3H domain protein
FM050_31750	COG0230	Belongs to the bacterial ribosomal protein bL34 family