locus-tag	class	description
M3Y14_00020	COG0516	GMP reductase activity
M3Y14_00020	COG0517	IMP dehydrogenase activity
M3Y14_00025	COG1686	Belongs to the peptidase S11 family
M3Y14_00035	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
M3Y14_00055	COG1428	Deoxynucleoside kinase
M3Y14_00060	COG1428	Deoxynucleoside kinase
M3Y14_00065	COG1335	isochorismatase
M3Y14_00070	COG0590	tRNA wobble adenosine to inosine editing
M3Y14_00080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M3Y14_00090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M3Y14_00110	COG1982	Orn Lys Arg decarboxylase major
M3Y14_00115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M3Y14_00120	COG0470	DNA polymerase III
M3Y14_00125	COG1774	PSP1 C-terminal conserved region
M3Y14_00130	COG4467	Involved in initiation control of chromosome replication
M3Y14_00135	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M3Y14_00145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M3Y14_00150	COG2002	toxin-antitoxin pair type II binding
M3Y14_00160	COG0084	hydrolase, TatD family'
M3Y14_00165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M3Y14_00170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M3Y14_00180	COG4466	Protein conserved in bacteria
M3Y14_00195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M3Y14_00200	COG0251	oxidation-reduction process
M3Y14_00205	COG2088	sporulation resulting in formation of a cellular spore
M3Y14_00210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
M3Y14_00230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M3Y14_00235	COG2002	toxin-antitoxin pair type II binding
M3Y14_00240	COG2244	polysaccharide biosynthetic process
M3Y14_00245	COG3956	TIGRFAM MazG family protein
M3Y14_00250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M3Y14_00270	COG1098	S1 RNA binding domain
M3Y14_00285	COG2208	phosphoserine phosphatase activity
M3Y14_00295	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M3Y14_00300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M3Y14_00310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M3Y14_00315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M3Y14_00320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M3Y14_00325	COG0512	Glutamine amidotransferase of anthranilate synthase
M3Y14_00330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M3Y14_00335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M3Y14_00340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M3Y14_00345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M3Y14_00350	COG1396	sequence-specific DNA binding
M3Y14_00355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M3Y14_00370	COG3880	PFAM UvrB UvrC protein
M3Y14_00375	COG3869	Catalyzes the specific phosphorylation of arginine residues in
M3Y14_00380	COG0542	response to heat
M3Y14_00385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M3Y14_00390	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
M3Y14_00395	COG4956	integral membrane protein (PIN domain superfamily)
M3Y14_00400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M3Y14_00410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M3Y14_00415	COG1045	serine acetyltransferase
M3Y14_00420	COG0215	cysteine-tRNA ligase activity
M3Y14_00430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M3Y14_00435	COG3688	RNA-binding protein containing a PIN domain
M3Y14_00445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M3Y14_00450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M3Y14_00455	COG0250	Participates in transcription elongation, termination and antitermination
M3Y14_00460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
M3Y14_00465	COG0081	regulation of translation
M3Y14_00470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
M3Y14_00475	COG0222	ribosome binding
M3Y14_00480	COG2813	Specifically methylates the guanine in position
M3Y14_00485	COG0085	RNA polymerase activity
M3Y14_00490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M3Y14_00495	COG1358	cellular component organization or biogenesis
M3Y14_00500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
M3Y14_00510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
M3Y14_00515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
M3Y14_00520	COG0051	transcription antitermination factor activity, RNA binding
M3Y14_00525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
M3Y14_00530	COG0088	Forms part of the polypeptide exit tunnel
M3Y14_00535	COG0089	rRNA binding
M3Y14_00540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
M3Y14_00565	COG0255	Belongs to the universal ribosomal protein uL29 family
M3Y14_00570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M3Y14_00580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
M3Y14_00585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
M3Y14_00595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
M3Y14_00605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
M3Y14_00615	COG1841	ribosomal large subunit assembly
M3Y14_00620	COG0200	Binds to the 23S rRNA
M3Y14_00625	COG0201	protein transport
M3Y14_00630	COG0563	adenylate kinase activity
M3Y14_00635	COG0024	Methionine aminopeptidase
M3Y14_00645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M3Y14_00650	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
M3Y14_00655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
M3Y14_00680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M3Y14_00690	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M3Y14_00705	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3Y14_00710	COG0489	protein tyrosine kinase activity
M3Y14_00720	COG2194	sulfuric ester hydrolase activity
M3Y14_00725	COG0726	polysaccharide deacetylase
M3Y14_00760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M3Y14_00765	COG4856	YbbR-like protein
M3Y14_00785	COG1506	peptidase
M3Y14_00785	COG0823	Involved in the tonB-independent uptake of proteins
M3Y14_00785	COG4946	Tricorn protease homolog
M3Y14_00805	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_00810	COG2011	ABC-type metal ion transport system permease component
M3Y14_00815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M3Y14_00820	COG1464	Belongs to the NlpA lipoprotein family
M3Y14_00825	COG0604	alcohol dehydrogenase
M3Y14_00830	COG0277	FAD linked oxidase domain protein
M3Y14_00835	COG2271	Major facilitator Superfamily
M3Y14_00845	COG2814	Major facilitator Superfamily
M3Y14_00865	COG0601	transmembrane transport
M3Y14_00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M3Y14_00875	COG0444	Belongs to the ABC transporter superfamily
M3Y14_00880	COG4608	Belongs to the ABC transporter superfamily
M3Y14_00885	COG4166	transmembrane transport
M3Y14_00895	COG1309	transcriptional regulator
M3Y14_00905	COG4166	transmembrane transport
M3Y14_00910	COG4166	transmembrane transport
M3Y14_00915	COG0656	L-ascorbic acid biosynthetic process
M3Y14_00935	COG4149	molybdate abc transporter
M3Y14_00940	COG0725	ABC transporter, periplasmic molybdate-binding protein
M3Y14_00945	COG1910	domain protein
M3Y14_00960	COG0697	spore germination
M3Y14_00975	COG1609	Transcriptional regulator
M3Y14_00985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_01000	COG5298	Protein conserved in bacteria
M3Y14_01025	COG0488	(ABC) transporter
M3Y14_01030	COG4585	Histidine kinase
M3Y14_01035	COG2197	response regulator
M3Y14_01040	COG1131	(ABC) transporter
M3Y14_01045	COG1511	domain protein
M3Y14_01045	COG0842	Transport permease protein
M3Y14_01050	COG0842	Transport permease protein
M3Y14_01060	COG0747	negative chemotaxis
M3Y14_01065	COG0747	negative chemotaxis
M3Y14_01070	COG0601	transmembrane transport
M3Y14_01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M3Y14_01080	COG0444	Belongs to the ABC transporter superfamily
M3Y14_01085	COG4608	Belongs to the ABC transporter superfamily
M3Y14_01090	COG0561	phosphatase activity
M3Y14_01120	COG3185	4-Hydroxyphenylpyruvate dioxygenase
M3Y14_01125	COG0179	Fumarylacetoacetate (FAA) hydrolase
M3Y14_01135	COG0531	amino acid
M3Y14_01140	COG2814	Major facilitator Superfamily
M3Y14_01150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M3Y14_01160	COG4294	response to UV
M3Y14_01165	COG0705	Rhomboid family
M3Y14_01170	COG0736	holo-[acyl-carrier-protein] synthase activity
M3Y14_01175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M3Y14_01180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M3Y14_01185	COG0864	Transcriptional regulator
M3Y14_01190	COG2337	Toxic component of a toxin-antitoxin (TA) module
M3Y14_01195	COG2183	response to ionizing radiation
M3Y14_01265	COG0802	atpase or kinase
M3Y14_01270	COG1214	PFAM Peptidase M22, glycoprotease
M3Y14_01275	COG0456	acetyltransferase
M3Y14_01285	COG0488	(ABC) transporter
M3Y14_01290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
M3Y14_01300	COG1266	CAAX protease self-immunity
M3Y14_01305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
M3Y14_01310	COG0459	protein refolding
M3Y14_01315	COG0519	Catalyzes the synthesis of GMP from XMP
M3Y14_01315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M3Y14_01320	COG2252	PERMEase
M3Y14_01330	COG5002	protein histidine kinase activity
M3Y14_01340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M3Y14_01380	COG2226	methyltransferase
M3Y14_01390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M3Y14_01405	COG0697	spore germination
M3Y14_01415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M3Y14_01420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M3Y14_01425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M3Y14_01435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M3Y14_01440	COG0047	phosphoribosylformylglycinamidine synthase activity
M3Y14_01450	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M3Y14_01460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M3Y14_01465	COG0138	bifunctional purine biosynthesis protein purh
M3Y14_01470	COG0151	Belongs to the GarS family
M3Y14_01490	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
M3Y14_01495	COG0210	DNA helicase
M3Y14_01500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M3Y14_01505	COG4851	CamS sex pheromone cAM373 precursor
M3Y14_01515	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_01520	COG1335	isochorismatase
M3Y14_01530	COG2011	ABC-type metal ion transport system permease component
M3Y14_01535	COG1464	Belongs to the NlpA lipoprotein family
M3Y14_01550	COG0003	Pfam Anion-transporting ATPase
M3Y14_01555	COG1846	Transcriptional regulator
M3Y14_01575	COG1396	sequence-specific DNA binding
M3Y14_01655	COG1674	ftsk spoiiie
M3Y14_01685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M3Y14_01690	COG1597	lipid kinase activity
M3Y14_01700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M3Y14_01710	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_01715	COG2076	Multidrug Resistance protein
M3Y14_01720	COG2309	aminopeptidase activity
M3Y14_01735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3Y14_01745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M3Y14_01750	COG5002	protein histidine kinase activity
M3Y14_01755	COG4807	Protein conserved in bacteria
M3Y14_01780	COG1757	Na H antiporter
M3Y14_01785	COG1473	amidohydrolase
M3Y14_01800	COG0450	alkyl hydroperoxide reductase
M3Y14_01810	COG3279	Response regulator of the LytR AlgR family
M3Y14_01815	COG0745	RESPONSE REGULATOR receiver
M3Y14_01815	COG2972	Histidine kinase
M3Y14_01825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
M3Y14_01835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_01840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_01845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3Y14_01850	COG0492	ferredoxin-NADP+ reductase activity
M3Y14_01860	COG0166	Belongs to the GPI family
M3Y14_01885	COG5002	protein histidine kinase activity
M3Y14_01905	COG3541	Predicted nucleotidyltransferase
M3Y14_01910	COG2814	Major facilitator Superfamily
M3Y14_01915	COG0723	plastoquinol--plastocyanin reductase activity
M3Y14_01915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3Y14_01925	COG0765	amino acid transport
M3Y14_01930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Y14_01940	COG0840	transmembrane signaling receptor activity
M3Y14_01945	COG0277	FAD linked oxidase domain protein
M3Y14_01950	COG0366	Alpha amylase catalytic
M3Y14_01955	COG1263	PTS System
M3Y14_01955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3Y14_01955	COG2190	(PTS) system
M3Y14_01975	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
M3Y14_01980	COG0352	thiamine-phosphate diphosphorylase activity
M3Y14_01985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M3Y14_02000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Y14_02005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Y14_02010	COG1116	anion transmembrane transporter activity
M3Y14_02020	COG0488	(ABC) transporter
M3Y14_02065	COG2270	Major facilitator Superfamily
M3Y14_02095	COG2310	stress, protein
M3Y14_02100	COG2310	stress, protein
M3Y14_02105	COG2310	stress, protein
M3Y14_02110	COG0861	Integral membrane protein TerC family
M3Y14_02120	COG3853	Toxic anion resistance protein (TelA)
M3Y14_02130	COG4840	Belongs to the UPF0435 family
M3Y14_02135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M3Y14_02145	COG1295	ribonuclease BN
M3Y14_02150	COG2217	Heavy metal translocating P-type atpase
M3Y14_02155	COG0697	spore germination
M3Y14_02175	COG0586	Pfam SNARE associated Golgi protein
M3Y14_02190	COG3871	stress protein (general stress protein 26)
M3Y14_02195	COG0387	Pfam Sodium calcium exchanger
M3Y14_02205	COG0535	radical SAM domain protein
M3Y14_02225	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M3Y14_02245	COG3829	transcription factor binding
M3Y14_02255	COG0833	amino acid
M3Y14_02260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M3Y14_02285	COG1263	PTS System
M3Y14_02285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3Y14_02290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M3Y14_02305	COG1216	Glycosyl transferase, family 2
M3Y14_02315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M3Y14_02315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M3Y14_02320	COG0463	Glycosyl transferase, family 2
M3Y14_02330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M3Y14_02335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M3Y14_02350	COG1228	amidohydrolase
M3Y14_02355	COG1090	epimerase
M3Y14_02360	COG2137	regulation of response to DNA damage stimulus
M3Y14_02385	COG1988	membrane-bound metal-dependent
M3Y14_02390	COG1194	a g-specific adenine glycosylase
M3Y14_02410	COG3557	Belongs to the UPF0374 family
M3Y14_02415	COG1132	(ABC) transporter
M3Y14_02420	COG4129	membrane
M3Y14_02425	COG0067	glutamate synthase
M3Y14_02425	COG0070	glutamate synthase
M3Y14_02425	COG0069	glutamate synthase activity
M3Y14_02430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
M3Y14_02435	COG4555	ABC transporter
M3Y14_02455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M3Y14_02460	COG0735	belongs to the Fur family
M3Y14_02550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M3Y14_02555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M3Y14_02575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M3Y14_02585	COG2766	serine protein kinase
M3Y14_02590	COG2718	Belongs to the UPF0229 family
M3Y14_02605	COG1585	Membrane protein implicated in regulation of membrane protease activity
M3Y14_02610	COG2268	Band 7 protein
M3Y14_02620	COG3290	protein histidine kinase activity
M3Y14_02625	COG4565	transcriptional regulatory protein
M3Y14_02630	COG2851	Citrate transporter
M3Y14_02655	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M3Y14_02660	COG3842	ATPase activity
M3Y14_02665	COG1175	transmembrane transport
M3Y14_02670	COG0395	ABC-type sugar transport system, permease component
M3Y14_02680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M3Y14_02685	COG0745	RESPONSE REGULATOR receiver
M3Y14_02690	COG5002	protein histidine kinase activity
M3Y14_02700	COG4990	cell redox homeostasis
M3Y14_02710	COG3290	protein histidine kinase activity
M3Y14_02715	COG4565	transcriptional regulatory protein
M3Y14_02720	COG3493	citrate carrier protein
M3Y14_02725	COG0281	malic enzyme
M3Y14_02735	COG0697	spore germination
M3Y14_02740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_02750	COG5002	protein histidine kinase activity
M3Y14_02755	COG0745	RESPONSE REGULATOR receiver
M3Y14_02760	COG0456	acetyltransferase
M3Y14_02765	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M3Y14_02770	COG3383	formate dehydrogenase (NAD+) activity
M3Y14_02775	COG2427	Protein of unknown function (DUF1641)
M3Y14_02790	COG0531	amino acid
M3Y14_02800	COG0640	Transcriptional regulator
M3Y14_02805	COG2217	Heavy metal translocating P-type atpase
M3Y14_02810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M3Y14_02825	COG3227	Zinc metalloprotease (Elastase)
M3Y14_02845	COG2720	vancomycin resistance protein
M3Y14_02850	COG1316	TRANSCRIPTIONal
M3Y14_02855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3Y14_02860	COG0346	lactoylglutathione lyase activity
M3Y14_02865	COG1253	flavin adenine dinucleotide binding
M3Y14_02870	COG1027	Aspartate ammonia-lyase
M3Y14_02875	COG1620	l-lactate permease
M3Y14_02890	COG3104	oligopeptide transport
M3Y14_02895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3Y14_02900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_02905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_02925	COG0156	8-amino-7-oxononanoate synthase activity
M3Y14_02930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M3Y14_02935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M3Y14_02945	COG4548	von Willebrand factor, type A
M3Y14_02950	COG0714	Associated with various cellular activities
M3Y14_02955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3Y14_02975	COG0531	amino acid
M3Y14_02980	COG2188	Transcriptional regulator
M3Y14_02985	COG1263	PTS System
M3Y14_02985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3Y14_02990	COG0366	Alpha amylase catalytic
M3Y14_03005	COG0697	spore germination
M3Y14_03015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M3Y14_03020	COG1115	amino acid carrier protein
M3Y14_03025	COG1126	abc transporter atp-binding protein
M3Y14_03030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Y14_03035	COG0765	amino acid transport
M3Y14_03040	COG0765	amino acid transport
M3Y14_03045	COG0833	amino acid
M3Y14_03060	COG1595	DNA-templated transcription, initiation
M3Y14_03070	COG2378	regulation of single-species biofilm formation
M3Y14_03075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M3Y14_03080	COG5002	protein histidine kinase activity
M3Y14_03100	COG2814	Major facilitator Superfamily
M3Y14_03105	COG0659	secondary active sulfate transmembrane transporter activity
M3Y14_03120	COG0747	negative chemotaxis
M3Y14_03130	COG0601	transmembrane transport
M3Y14_03135	COG4608	Belongs to the ABC transporter superfamily
M3Y14_03145	COG2271	Major facilitator Superfamily
M3Y14_03150	COG1846	Transcriptional regulator
M3Y14_03155	COG0477	Major facilitator Superfamily
M3Y14_03160	COG1609	Transcriptional regulator
M3Y14_03165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M3Y14_03170	COG1869	D-ribose catabolic process
M3Y14_03180	COG1172	Belongs to the binding-protein-dependent transport system permease family
M3Y14_03185	COG1879	ABC-type sugar transport system periplasmic component
M3Y14_03215	COG1063	alcohol dehydrogenase
M3Y14_03230	COG3568	Endonuclease Exonuclease Phosphatase
M3Y14_03260	COG0840	transmembrane signaling receptor activity
M3Y14_03265	COG1388	LysM domain
M3Y14_03265	COG3584	3D domain protein
M3Y14_03270	COG1476	TRANSCRIPTIONal
M3Y14_03290	COG3104	oligopeptide transport
M3Y14_03305	COG1114	Component of the transport system for branched-chain amino acids
M3Y14_03320	COG1113	amino acid transport
M3Y14_03325	COG2252	PERMEase
M3Y14_03340	COG2153	protein acetylation
M3Y14_03350	COG0569	domain protein
M3Y14_03350	COG0475	glutathione-regulated potassium exporter activity
M3Y14_03360	COG1845	cytochrome c oxidase, subunit III
M3Y14_03365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M3Y14_03375	COG0833	amino acid
M3Y14_03380	COG4990	cell redox homeostasis
M3Y14_03400	COG0697	spore germination
M3Y14_03405	COG0531	amino acid
M3Y14_03420	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M3Y14_03425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M3Y14_03435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M3Y14_03440	COG0573	inorganic phosphate transmembrane transporter activity
M3Y14_03445	COG0581	inorganic phosphate transmembrane transporter activity
M3Y14_03455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M3Y14_03490	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M3Y14_03505	COG3103	Sh3 type 3 domain protein
M3Y14_03505	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3Y14_03505	COG4991	sh3 domain protein
M3Y14_03510	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M3Y14_03515	COG1116	anion transmembrane transporter activity
M3Y14_03520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Y14_03525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Y14_03530	COG0352	thiamine-phosphate diphosphorylase activity
M3Y14_03535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3Y14_03540	COG2104	thiamine diphosphate biosynthetic process
M3Y14_03550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M3Y14_03555	COG0351	phosphomethylpyrimidine kinase
M3Y14_03580	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M3Y14_03585	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M3Y14_03590	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
M3Y14_03595	COG2205	protein histidine kinase activity
M3Y14_03600	COG2814	Major facilitator Superfamily
M3Y14_03605	COG1846	Transcriptional regulator
M3Y14_03625	COG1172	Belongs to the binding-protein-dependent transport system permease family
M3Y14_03630	COG1129	ABC transporter
M3Y14_03640	COG2252	PERMEase
M3Y14_03645	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_03650	COG1376	ErfK ybiS ycfS ynhG family protein
M3Y14_03705	COG0778	Nitroreductase
M3Y14_03710	COG2719	SpoVR family
M3Y14_03720	COG0446	pyridine nucleotide-disulphide oxidoreductase
M3Y14_03725	COG1937	Protein conserved in bacteria
M3Y14_03730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3Y14_03730	COG0425	Belongs to the sulfur carrier protein TusA family
M3Y14_03735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3Y14_03735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_03740	COG0425	Belongs to the sulfur carrier protein TusA family
M3Y14_03745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3Y14_03745	COG0425	Belongs to the sulfur carrier protein TusA family
M3Y14_03750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3Y14_03755	COG2210	Belongs to the sulfur carrier protein TusA family
M3Y14_03760	COG0730	response to heat
M3Y14_03765	COG0577	efflux transmembrane transporter activity
M3Y14_03770	COG1136	(ABC) transporter
M3Y14_03790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M3Y14_03795	COG0577	efflux transmembrane transporter activity
M3Y14_03800	COG1114	Component of the transport system for branched-chain amino acids
M3Y14_03805	COG3546	catalase activity
M3Y14_03830	COG0586	Pfam SNARE associated Golgi protein
M3Y14_03860	COG0531	amino acid
M3Y14_03875	COG1737	Transcriptional regulator
M3Y14_03885	COG1263	PTS System
M3Y14_03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3Y14_03895	COG2259	Doxx family
M3Y14_03915	COG1522	sequence-specific DNA binding
M3Y14_03925	COG0300	oxidoreductase activity
M3Y14_03940	COG2076	Multidrug Resistance protein
M3Y14_03945	COG1309	transcriptional regulator
M3Y14_03950	COG2814	Major facilitator Superfamily
M3Y14_03955	COG1733	regulation of RNA biosynthetic process
M3Y14_03965	COG2249	NAD(P)H dehydrogenase (quinone) activity
M3Y14_03975	COG4533	DNA binding
M3Y14_04010	COG3620	sequence-specific DNA binding
M3Y14_04120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M3Y14_04210	COG5632	N-Acetylmuramoyl-L-alanine amidase
M3Y14_04255	COG0531	amino acid
M3Y14_04260	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_04265	COG1132	(ABC) transporter
M3Y14_04270	COG1132	(ABC) transporter
M3Y14_04275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Y14_04280	COG0765	amino acid transport
M3Y14_04285	COG1126	abc transporter atp-binding protein
M3Y14_04300	COG0189	ligase activity
M3Y14_04315	COG3679	Belongs to the UPF0342 family
M3Y14_04330	COG0028	Belongs to the TPP enzyme family
M3Y14_04335	COG3527	Alpha-acetolactate decarboxylase
M3Y14_04340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M3Y14_04350	COG0561	phosphatase activity
M3Y14_04355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M3Y14_04370	COG0586	Pfam SNARE associated Golgi protein
M3Y14_04380	COG0789	Transcriptional regulator
M3Y14_04380	COG4978	Transcriptional regulator
M3Y14_04390	COG0659	secondary active sulfate transmembrane transporter activity
M3Y14_04410	COG2244	polysaccharide biosynthetic process
M3Y14_04440	COG1024	Enoyl-CoA hydratase
M3Y14_04455	COG1363	Peptidase, m42
M3Y14_04495	COG0579	oxidoreductase
M3Y14_04515	COG0601	transmembrane transport
M3Y14_04520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M3Y14_04525	COG0444	Belongs to the ABC transporter superfamily
M3Y14_04530	COG4608	Belongs to the ABC transporter superfamily
M3Y14_04610	COG0477	Major facilitator Superfamily
M3Y14_04615	COG3290	protein histidine kinase activity
M3Y14_04620	COG4565	transcriptional regulatory protein
M3Y14_04625	COG3181	Tripartite tricarboxylate transporter family receptor
M3Y14_04710	COG4978	Transcriptional regulator
M3Y14_04710	COG0789	Transcriptional regulator
M3Y14_04725	COG0305	Participates in initiation and elongation during chromosome replication
M3Y14_04780	COG2814	Major facilitator Superfamily
M3Y14_04785	COG0640	Transcriptional regulator
M3Y14_04790	COG3711	transcriptional antiterminator
M3Y14_04795	COG2190	(PTS) system
M3Y14_04795	COG1263	PTS System
M3Y14_04795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3Y14_04800	COG2723	6-phospho-beta-galactosidase activity
M3Y14_04815	COG2376	Dihydroxyacetone kinase
M3Y14_04825	COG2376	Dihydroxyacetone kinase
M3Y14_04835	COG0457	Tetratricopeptide repeat
M3Y14_04845	COG1335	isochorismatase
M3Y14_04880	COG2807	transmembrane transport
M3Y14_04905	COG4585	Histidine kinase
M3Y14_04910	COG2197	response regulator
M3Y14_04940	COG0420	3'-5' exonuclease activity
M3Y14_04945	COG4717	serine-type aminopeptidase activity
M3Y14_04950	COG3481	metal-dependent phosphohydrolase, HD sub domain
M3Y14_04955	COG1309	transcriptional regulator
M3Y14_04960	COG2814	Major facilitator Superfamily
M3Y14_04965	COG0346	lactoylglutathione lyase activity
M3Y14_04970	COG0346	lactoylglutathione lyase activity
M3Y14_04985	COG2267	carboxylic ester hydrolase activity
M3Y14_04995	COG2140	Oxalate decarboxylase
M3Y14_05000	COG3620	sequence-specific DNA binding
M3Y14_05005	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M3Y14_05010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M3Y14_05015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M3Y14_05020	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M3Y14_05035	COG1595	DNA-templated transcription, initiation
M3Y14_05045	COG0772	Belongs to the SEDS family
M3Y14_05055	COG3973	AAA domain
M3Y14_05075	COG1846	Transcriptional regulator
M3Y14_05085	COG0537	adenosine 5'-monophosphoramidase activity
M3Y14_05090	COG1131	(ABC) transporter
M3Y14_05095	COG4473	ABC transporter
M3Y14_05105	COG0247	lactate metabolic process
M3Y14_05110	COG1139	Iron-sulfur cluster binding protein
M3Y14_05115	COG1556	Lactate utilization protein
M3Y14_05135	COG3402	PFAM membrane-flanked domain
M3Y14_05140	COG3428	Bacterial PH domain
M3Y14_05180	COG1136	(ABC) transporter
M3Y14_05185	COG0577	efflux transmembrane transporter activity
M3Y14_05200	COG3402	PFAM membrane-flanked domain
M3Y14_05205	COG3428	Bacterial PH domain
M3Y14_05210	COG2329	Antibiotic biosynthesis monooxygenase
M3Y14_05215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3Y14_05230	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M3Y14_05270	COG1309	transcriptional regulator
M3Y14_05275	COG1511	domain protein
M3Y14_05275	COG1511	domain protein
M3Y14_05310	COG2378	regulation of single-species biofilm formation
M3Y14_05315	COG1609	Transcriptional regulator
M3Y14_05325	COG1234	tRNA 3'-trailer cleavage
M3Y14_05330	COG0095	Lipoate-protein ligase
M3Y14_05335	COG0318	PFAM AMP-dependent synthetase and ligase
M3Y14_05345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M3Y14_05355	COG4208	sulfate ABC transporter
M3Y14_05365	COG1408	metallophosphoesterase
M3Y14_05370	COG1078	dGTPase activity
M3Y14_05385	COG1595	DNA-templated transcription, initiation
M3Y14_05390	COG2207	Transcriptional regulator
M3Y14_05390	COG3708	Transcriptional regulator
M3Y14_05395	COG2205	protein histidine kinase activity
M3Y14_05400	COG0745	RESPONSE REGULATOR receiver
M3Y14_05425	COG0501	Belongs to the peptidase M48B family
M3Y14_05430	COG0697	spore germination
M3Y14_05445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M3Y14_05450	COG2224	Isocitrate lyase
M3Y14_05460	COG1278	Cold shock
M3Y14_05470	COG4903	ComK protein
M3Y14_05480	COG0398	Pfam SNARE associated Golgi protein
M3Y14_05490	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
M3Y14_05545	COG0179	Fumarylacetoacetate (FAA) hydrolase
M3Y14_05570	COG0367	asparagine synthase
M3Y14_05585	COG0753	catalase activity
M3Y14_05605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M3Y14_05625	COG3339	Conserved Protein
M3Y14_05630	COG0004	ammonium transporteR
M3Y14_05650	COG2996	Protein conserved in bacteria
M3Y14_05665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M3Y14_05675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_05690	COG0561	phosphatase activity
M3Y14_05710	COG2267	carboxylic ester hydrolase activity
M3Y14_05725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M3Y14_05730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M3Y14_05735	COG5504	Zn-dependent protease
M3Y14_05745	COG0180	Tryptophanyl-tRNA synthetase
M3Y14_05755	COG4166	transmembrane transport
M3Y14_05760	COG0601	transmembrane transport
M3Y14_05765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M3Y14_05770	COG0444	Belongs to the ABC transporter superfamily
M3Y14_05775	COG4608	Belongs to the ABC transporter superfamily
M3Y14_05795	COG0534	Mate efflux family protein
M3Y14_05800	COG4166	transmembrane transport
M3Y14_05815	COG0861	Integral membrane protein TerC family
M3Y14_05820	COG4862	establishment of competence for transformation
M3Y14_05825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3Y14_05835	COG1164	Oligoendopeptidase f
M3Y14_05850	COG2346	COG2346, Truncated hemoglobins
M3Y14_05855	COG4116	CYTH
M3Y14_05865	COG2357	RelA SpoT domain protein
M3Y14_05875	COG0564	pseudouridine synthase activity
M3Y14_05885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M3Y14_05890	COG0772	Belongs to the SEDS family
M3Y14_05895	COG1216	Glycosyl transferase, family 2
M3Y14_05915	COG0457	Tetratricopeptide repeat
M3Y14_05915	COG0463	Glycosyl transferase, family 2
M3Y14_05935	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M3Y14_05950	COG1091	dTDP-4-dehydrorhamnose reductase activity
M3Y14_05995	COG2153	protein acetylation
M3Y14_06000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M3Y14_06005	COG2382	esterase
M3Y14_06030	COG5492	domain, Protein
M3Y14_06035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M3Y14_06045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M3Y14_06045	COG0512	Glutamine amidotransferase of anthranilate synthase
M3Y14_06050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M3Y14_06055	COG0134	indole-3-glycerol-phosphate synthase activity
M3Y14_06060	COG0135	phosphoribosylanthranilate isomerase activity
M3Y14_06065	COG0133	tryptophan synthase activity
M3Y14_06070	COG0159	tryptophan synthase activity
M3Y14_06080	COG1620	l-lactate permease
M3Y14_06085	COG5634	Uncharacterized conserved protein (DUF2278)
M3Y14_06125	COG2226	methyltransferase
M3Y14_06145	COG0508	dehydrogenase complex catalyzes the overall conversion of
M3Y14_06150	COG0567	Dehydrogenase, E1 component
M3Y14_06155	COG1476	TRANSCRIPTIONal
M3Y14_06200	COG1686	Belongs to the peptidase S11 family
M3Y14_06205	COG0681	Belongs to the peptidase S26 family
M3Y14_06240	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_06250	COG1176	ABC-type spermidine putrescine transport system, permease component I
M3Y14_06255	COG1177	transmembrane transport
M3Y14_06260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M3Y14_06270	COG2409	Drug exporters of the RND superfamily
M3Y14_06280	COG0564	pseudouridine synthase activity
M3Y14_06290	COG2340	Cysteine-rich secretory protein family
M3Y14_06295	COG0247	lactate metabolic process
M3Y14_06300	COG0277	FAD linked oxidase domain protein
M3Y14_06305	COG3835	regulator
M3Y14_06315	COG0745	RESPONSE REGULATOR receiver
M3Y14_06320	COG5002	protein histidine kinase activity
M3Y14_06320	COG3850	Histidine kinase
M3Y14_06325	COG2186	Transcriptional regulator
M3Y14_06340	COG1556	Lactate utilization protein
M3Y14_06345	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M3Y14_06355	COG2116	formate transmembrane transporter activity
M3Y14_06360	COG0861	Integral membrane protein TerC family
M3Y14_06365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M3Y14_06375	COG2030	dehydratase
M3Y14_06395	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_06400	COG3243	poly(R)-hydroxyalkanoic acid synthase
M3Y14_06410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M3Y14_06425	COG1840	ABC-type Fe3 transport system, periplasmic component
M3Y14_06430	COG3842	ATPase activity
M3Y14_06440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M3Y14_06445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M3Y14_06455	COG1349	DNA-binding transcription factor activity
M3Y14_06465	COG0235	Class ii aldolase
M3Y14_06475	COG2861	carbohydrate metabolic process
M3Y14_06485	COG3852	Histidine kinase
M3Y14_06490	COG1846	Transcriptional regulator
M3Y14_06500	COG2318	DinB family
M3Y14_06510	COG5002	protein histidine kinase activity
M3Y14_06520	COG0720	synthase
M3Y14_06535	COG4873	Protein conserved in bacteria
M3Y14_06565	COG1780	Probably involved in ribonucleotide reductase function
M3Y14_06580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M3Y14_06585	COG0531	amino acid
M3Y14_06590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M3Y14_06605	COG2204	response regulator
M3Y14_06610	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_06620	COG1725	Transcriptional regulator
M3Y14_06625	COG1131	(ABC) transporter
M3Y14_06635	COG1131	(ABC) transporter
M3Y14_06640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M3Y14_06645	COG1266	CAAX protease self-immunity
M3Y14_06655	COG1522	sequence-specific DNA binding
M3Y14_06665	COG1335	isochorismatase
M3Y14_06675	COG1619	proteins homologs of microcin C7 resistance protein MccF
M3Y14_06680	COG2070	2-Nitropropane dioxygenase
M3Y14_06685	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M3Y14_06690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Y14_06695	COG1696	Membrane protein involved in D-alanine export
M3Y14_06720	COG0716	FMN binding
M3Y14_06735	COG3173	Aminoglycoside phosphotransferase
M3Y14_06755	COG0534	Mate efflux family protein
M3Y14_06775	COG1846	Transcriptional regulator
M3Y14_06790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M3Y14_06800	COG3874	Sporulation protein YtfJ
M3Y14_06820	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M3Y14_06825	COG0028	Belongs to the TPP enzyme family
M3Y14_06830	COG0440	acetolactate synthase activity
M3Y14_06840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M3Y14_06850	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M3Y14_06860	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
M3Y14_06865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M3Y14_06880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M3Y14_06890	COG0107	imidazoleglycerol-phosphate synthase activity
M3Y14_06900	COG0140	phosphoribosyl-ATP diphosphatase activity
M3Y14_06905	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M3Y14_06920	COG1183	phosphatidylcholine synthase activity
M3Y14_06925	COG1368	sulfuric ester hydrolase activity
M3Y14_06935	COG0019	diaminopimelate decarboxylase activity
M3Y14_06955	COG0529	Catalyzes the synthesis of activated sulfate
M3Y14_06960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Y14_06980	COG1648	precorrin-2 dehydrogenase activity
M3Y14_06985	COG0733	neurotransmitter:sodium symporter activity
M3Y14_07010	COG1757	Na H antiporter
M3Y14_07030	COG4758	membrane
M3Y14_07035	COG4585	Histidine kinase
M3Y14_07040	COG2197	response regulator
M3Y14_07050	COG1114	Component of the transport system for branched-chain amino acids
M3Y14_07100	COG0730	response to heat
M3Y14_07105	COG0306	phosphate transporter
M3Y14_07110	COG1392	Phosphate transport regulator
M3Y14_07115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3Y14_07130	COG3852	Histidine kinase
M3Y14_07135	COG1801	Protein of unknown function DUF72
M3Y14_07145	COG0582	viral genome integration into host DNA
M3Y14_07150	COG5002	protein histidine kinase activity
M3Y14_07165	COG0392	lysyltransferase activity
M3Y14_07165	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M3Y14_07180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M3Y14_07185	COG1686	Belongs to the peptidase S11 family
M3Y14_07190	COG2715	membrane protein required for spore maturation
M3Y14_07195	COG0700	Nucleoside recognition
M3Y14_07200	COG1187	pseudouridine synthase activity
M3Y14_07210	COG1333	cytochrome c biogenesis protein
M3Y14_07215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M3Y14_07220	COG0745	RESPONSE REGULATOR receiver
M3Y14_07225	COG5002	protein histidine kinase activity
M3Y14_07230	COG2096	Adenosyltransferase
M3Y14_07235	COG4942	peptidase
M3Y14_07245	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M3Y14_07250	COG1141	Ferredoxin
M3Y14_07255	COG4955	Helix-turn-helix domain
M3Y14_07260	COG0514	ATP-dependent DNA helicase (RecQ)
M3Y14_07265	COG1266	CAAX protease self-immunity
M3Y14_07275	COG1408	metallophosphoesterase
M3Y14_07290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M3Y14_07310	COG0492	ferredoxin-NADP+ reductase activity
M3Y14_07315	COG0252	asparaginase activity
M3Y14_07325	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
M3Y14_07335	COG1304	FMN binding
M3Y14_07365	COG1160	GTP binding
M3Y14_07390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M3Y14_07405	COG0142	geranyltranstransferase activity
M3Y14_07410	COG2226	methyltransferase
M3Y14_07415	COG0142	geranyltranstransferase activity
M3Y14_07430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
M3Y14_07440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M3Y14_07445	COG0457	Tetratricopeptide repeat
M3Y14_07450	COG5582	Belongs to the UPF0302 family
M3Y14_07465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M3Y14_07470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M3Y14_07470	COG2010	Cytochrome c
M3Y14_07475	COG4347	Protein of unknown function (DUF1405)
M3Y14_07490	COG2738	Putative neutral zinc metallopeptidase
M3Y14_07500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_07505	COG1694	Mazg nucleotide pyrophosphohydrolase
M3Y14_07510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
M3Y14_07515	COG1803	Methylglyoxal synthase
M3Y14_07520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M3Y14_07525	COG0438	transferase activity, transferring glycosyl groups
M3Y14_07530	COG0617	tRNA 3'-terminal CCA addition
M3Y14_07540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
M3Y14_07545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
M3Y14_07555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M3Y14_07555	COG1199	ATP-dependent helicase activity
M3Y14_07575	COG3935	DnaD domain protein
M3Y14_07580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M3Y14_07590	COG4499	WXG100 protein secretion system (Wss), protein YukC
M3Y14_07590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3Y14_07595	COG3331	DNA recombination
M3Y14_07630	COG4474	Belongs to the UPF0398 family
M3Y14_07635	COG3599	regulation of cell shape
M3Y14_07645	COG0116	Belongs to the methyltransferase superfamily
M3Y14_07655	COG1199	ATP-dependent helicase activity
M3Y14_07660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M3Y14_07665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_07670	COG0024	Methionine aminopeptidase
M3Y14_07680	COG2233	PERMEase
M3Y14_07685	COG2311	Membrane
M3Y14_07695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M3Y14_07705	COG0456	acetyltransferase
M3Y14_07735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M3Y14_07760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M3Y14_07775	COG1215	transferase activity, transferring glycosyl groups
M3Y14_07780	COG0438	transferase activity, transferring glycosyl groups
M3Y14_07815	COG0328	RNA-DNA hybrid ribonuclease activity
M3Y14_07860	COG3403	YqcI/YcgG family
M3Y14_07865	COG1280	lysine exporter protein (LysE YggA)
M3Y14_07880	COG3162	membrane
M3Y14_07885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M3Y14_07890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M3Y14_07900	COG0475	glutathione-regulated potassium exporter activity
M3Y14_07905	COG0789	Transcriptional regulator
M3Y14_07905	COG4978	Transcriptional regulator
M3Y14_07915	COG2323	membrane
M3Y14_07920	COG1434	Gram-negative-bacterium-type cell wall biogenesis
M3Y14_07935	COG0693	protein deglycase activity
M3Y14_07980	COG1923	regulation of RNA biosynthetic process
M3Y14_07990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M3Y14_07995	COG1360	Flagellar Motor Protein
M3Y14_08000	COG2201	protein-glutamate methylesterase activity
M3Y14_08005	COG2198	Histidine kinase
M3Y14_08005	COG0643	Histidine kinase
M3Y14_08010	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M3Y14_08010	COG1776	CheC inhibitor of MCP methylation
M3Y14_08030	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M3Y14_08050	COG1256	bacterial-type flagellum assembly
M3Y14_08055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M3Y14_08075	COG1815	bacterial-type flagellum-dependent cell motility
M3Y14_08080	COG1558	bacterial-type flagellum-dependent cell motility
M3Y14_08090	COG1766	The M ring may be actively involved in energy transduction
M3Y14_08095	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M3Y14_08105	COG1157	protein secretion by the type III secretion system
M3Y14_08140	COG0784	Response regulator, receiver
M3Y14_08140	COG0835	chemotaxis
M3Y14_08165	COG0861	Integral membrane protein TerC family
M3Y14_08175	COG3383	formate dehydrogenase (NAD+) activity
M3Y14_08180	COG2427	Protein of unknown function (DUF1641)
M3Y14_08185	COG5609	conserved protein (DUF2294)
M3Y14_08190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M3Y14_08200	COG2116	formate transmembrane transporter activity
M3Y14_08205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M3Y14_08210	COG0303	'Molybdopterin
M3Y14_08215	COG0314	molybdopterin synthase activity
M3Y14_08220	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M3Y14_08230	COG0489	protein tyrosine kinase activity
M3Y14_08245	COG0741	lytic transglycosylase activity
M3Y14_08255	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M3Y14_08260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M3Y14_08260	COG1776	CheC inhibitor of MCP methylation
M3Y14_08270	COG1338	Plays a role in the flagellum-specific transport system
M3Y14_08275	COG1987	bacterial-type flagellum assembly
M3Y14_08285	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M3Y14_08290	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M3Y14_08295	COG1419	protein localization to endoplasmic reticulum
M3Y14_08300	COG4786	Flagellar basal body rod
M3Y14_08340	COG2329	Antibiotic biosynthesis monooxygenase
M3Y14_08375	COG0583	DNA-binding transcription factor activity
M3Y14_08380	COG3842	ATPase activity
M3Y14_08445	COG1846	Transcriptional regulator
M3Y14_08455	COG0367	asparagine synthase
M3Y14_08495	COG1216	Glycosyl transferase, family 2
M3Y14_08495	COG0438	transferase activity, transferring glycosyl groups
M3Y14_08500	COG1757	Na H antiporter
M3Y14_08535	COG0534	Mate efflux family protein
M3Y14_08540	COG3340	Belongs to the peptidase S51 family
M3Y14_08560	COG0785	Cytochrome C biogenesis protein
M3Y14_08565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M3Y14_08580	COG3048	D-serine ammonia-lyase activity
M3Y14_08585	COG2733	membrane
M3Y14_08620	COG1131	(ABC) transporter
M3Y14_08640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3Y14_08685	COG0528	UMP kinase activity
M3Y14_08695	COG1027	Aspartate ammonia-lyase
M3Y14_08700	COG0281	malic enzyme
M3Y14_08705	COG4191	Histidine kinase
M3Y14_08710	COG0784	Response regulator, receiver
M3Y14_08715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M3Y14_08770	COG2814	Major facilitator Superfamily
M3Y14_08790	COG1695	Transcriptional regulator
M3Y14_08800	COG0477	Major facilitator Superfamily
M3Y14_08815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M3Y14_08820	COG2223	nitrite transmembrane transporter activity
M3Y14_08825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M3Y14_08840	COG2244	polysaccharide biosynthetic process
M3Y14_08845	COG0733	neurotransmitter:sodium symporter activity
M3Y14_08850	COG5566	PFAM Mor transcription activator
M3Y14_08855	COG2323	membrane
M3Y14_08870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M3Y14_08885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M3Y14_08910	COG2814	Major facilitator Superfamily
M3Y14_08915	COG3384	dioxygenase
M3Y14_08960	COG4166	transmembrane transport
M3Y14_08990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_09010	COG1914	H( )-stimulated, divalent metal cation uptake system
M3Y14_09015	COG1054	Belongs to the UPF0176 family
M3Y14_09025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M3Y14_09030	COG0531	amino acid
M3Y14_09070	COG0745	RESPONSE REGULATOR receiver
M3Y14_09075	COG5002	protein histidine kinase activity
M3Y14_09105	COG2390	Transcriptional regulator
M3Y14_09115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M3Y14_09120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3Y14_09125	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M3Y14_09140	COG4846	Membrane protein involved in cytochrome C biogenesis
M3Y14_09160	COG0583	DNA-binding transcription factor activity
M3Y14_09175	COG0006	proline dipeptidase activity
M3Y14_09185	COG2132	Multicopper oxidase
M3Y14_09195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M3Y14_09205	COG0583	DNA-binding transcription factor activity
M3Y14_09225	COG1114	Component of the transport system for branched-chain amino acids
M3Y14_09235	COG4641	Protein conserved in bacteria
M3Y14_09245	COG1276	copper resistance
M3Y14_09245	COG2372	response to copper ion
M3Y14_09250	COG4549	nuclear export factor GLE1
M3Y14_09260	COG0697	spore germination
M3Y14_09265	COG0583	DNA-binding transcription factor activity
M3Y14_09270	COG1959	2 iron, 2 sulfur cluster binding
M3Y14_09275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M3Y14_09280	COG0778	Nitroreductase
M3Y14_09290	COG0628	permease
M3Y14_09305	COG1231	oxidoreductase activity
M3Y14_09310	COG0523	cobalamin synthesis protein
M3Y14_09320	COG0411	ABC transporter
M3Y14_09340	COG0583	DNA-binding transcription factor activity
M3Y14_09350	COG1942	4-Oxalocrotonate Tautomerase
M3Y14_09365	COG0346	lactoylglutathione lyase activity
M3Y14_09375	COG1271	oxidase subunit
M3Y14_09380	COG1294	oxidase, subunit
M3Y14_09385	COG4988	ABC transporter
M3Y14_09390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M3Y14_09415	COG1619	proteins homologs of microcin C7 resistance protein MccF
M3Y14_09420	COG1686	Belongs to the peptidase S11 family
M3Y14_09435	COG0791	NLP P60 protein
M3Y14_09435	COG1388	LysM domain
M3Y14_09445	COG1132	(ABC) transporter
M3Y14_09450	COG0745	RESPONSE REGULATOR receiver
M3Y14_09455	COG5002	protein histidine kinase activity
M3Y14_09460	COG0300	oxidoreductase activity
M3Y14_09465	COG4122	O-methyltransferase activity
M3Y14_09495	COG0460	homoserine dehydrogenase
M3Y14_09520	COG1316	TRANSCRIPTIONal
M3Y14_09530	COG0745	RESPONSE REGULATOR receiver
M3Y14_09535	COG5002	protein histidine kinase activity
M3Y14_09550	COG1285	pathogenesis
M3Y14_09555	COG1247	-acetyltransferase
M3Y14_09575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Y14_09585	COG1082	Xylose isomerase domain protein TIM barrel
M3Y14_09595	COG2814	Major facilitator Superfamily
M3Y14_09600	COG1279	arginine transmembrane transporter activity
M3Y14_09605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_09615	COG1752	Esterase of the alpha-beta hydrolase superfamily
M3Y14_09650	COG0577	efflux transmembrane transporter activity
M3Y14_09655	COG2002	toxin-antitoxin pair type II binding
M3Y14_09665	COG4974	Belongs to the 'phage' integrase family
M3Y14_09685	COG1404	Belongs to the peptidase S8 family
M3Y14_09690	COG0640	Transcriptional regulator
M3Y14_09695	COG0667	Aldo Keto reductase
M3Y14_09700	COG2814	Major facilitator Superfamily
M3Y14_09740	COG3949	Membrane
M3Y14_09745	COG0783	Belongs to the Dps family
M3Y14_09760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M3Y14_09770	COG1231	oxidoreductase activity
M3Y14_09775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_09780	COG4989	oxidoreductase activity
M3Y14_09785	COG0523	cobalamin synthesis protein
M3Y14_09800	COG0456	acetyltransferase
M3Y14_09805	COG0803	Belongs to the bacterial solute-binding protein 9 family
M3Y14_09820	COG1902	pentaerythritol trinitrate reductase activity
M3Y14_09825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M3Y14_09835	COG4166	transmembrane transport
M3Y14_09840	COG0346	lactoylglutathione lyase activity
M3Y14_09860	COG5337	Spore coat protein CotH
M3Y14_09865	COG1051	belongs to the nudix hydrolase family
M3Y14_09870	COG0586	Pfam SNARE associated Golgi protein
M3Y14_09875	COG2244	polysaccharide biosynthetic process
M3Y14_09885	COG0701	Predicted permease
M3Y14_09890	COG3689	TIGRFAM TIGR03943 family protein
M3Y14_09895	COG1607	acyl-coa hydrolase
M3Y14_09905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3Y14_09920	COG0702	epimerase
M3Y14_09925	COG2839	Protein conserved in bacteria
M3Y14_09930	COG1253	flavin adenine dinucleotide binding
M3Y14_09955	COG1114	Component of the transport system for branched-chain amino acids
M3Y14_09960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M3Y14_09980	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3Y14_09990	COG1876	peptidase activity
M3Y14_10005	COG2211	Major facilitator Superfamily
M3Y14_10030	COG0561	phosphatase activity
M3Y14_10040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M3Y14_10055	COG1819	glycosyl
M3Y14_10060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_10065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_10090	COG0456	acetyltransferase
M3Y14_10125	COG4499	WXG100 protein secretion system (Wss), protein YukC
M3Y14_10215	COG3874	Sporulation protein YtfJ
M3Y14_10240	COG2226	methyltransferase
M3Y14_10260	COG0346	lactoylglutathione lyase activity
M3Y14_10270	COG0604	alcohol dehydrogenase
M3Y14_10275	COG1595	DNA-templated transcription, initiation
M3Y14_10300	COG0426	domain, Protein
M3Y14_10300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Y14_10310	COG0386	Belongs to the glutathione peroxidase family
M3Y14_10315	COG1305	Transglutaminase-like
M3Y14_10320	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M3Y14_10325	COG0714	Associated with various cellular activities
M3Y14_10330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M3Y14_10335	COG1140	nitrate reductase beta subunit
M3Y14_10340	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M3Y14_10345	COG2181	nitrate reductase activity
M3Y14_10350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M3Y14_10355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M3Y14_10360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M3Y14_10365	COG0303	'Molybdopterin
M3Y14_10370	COG0314	molybdopterin synthase activity
M3Y14_10380	COG2223	nitrite transmembrane transporter activity
M3Y14_10395	COG1648	precorrin-2 dehydrogenase activity
M3Y14_10405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M3Y14_10405	COG1587	Uroporphyrinogen-III synthase
M3Y14_10410	COG2146	nitrite reductase [NAD(P)H] activity
M3Y14_10415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M3Y14_10420	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
M3Y14_10455	COG2359	stage V sporulation protein S
M3Y14_10465	COG1418	mRNA catabolic process
M3Y14_10470	COG0488	(ABC) transporter
M3Y14_10485	COG0629	single-stranded DNA binding
M3Y14_10505	COG1413	lyase activity
M3Y14_10520	COG2521	methyltransferase
M3Y14_10520	COG2136	Putative SAM-dependent methyltransferase
M3Y14_10575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M3Y14_10580	COG0017	Asparaginyl-tRNA synthetase
M3Y14_10585	COG0733	neurotransmitter:sodium symporter activity
M3Y14_10610	COG2610	gluconate transmembrane transporter activity
M3Y14_10615	COG1454	alcohol dehydrogenase
M3Y14_10620	COG1794	racemase activity, acting on amino acids and derivatives
M3Y14_10630	COG0456	acetyltransferase
M3Y14_10635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M3Y14_10645	COG1131	(ABC) transporter
M3Y14_10650	COG4473	ABC transporter
M3Y14_10660	COG0546	phosphoglycolate phosphatase activity
M3Y14_10700	COG0768	penicillin binding
M3Y14_10715	COG1272	protein, Hemolysin III
M3Y14_10720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M3Y14_10725	COG0805	protein transport
M3Y14_10735	COG1307	EDD domain protein, DegV family
M3Y14_10740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M3Y14_10745	COG1999	signal sequence binding
M3Y14_10750	COG0071	Belongs to the small heat shock protein (HSP20) family
M3Y14_10755	COG0367	asparagine synthase
M3Y14_10770	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3Y14_10775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3Y14_10780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M3Y14_10795	COG1335	isochorismatase
M3Y14_10800	COG1051	belongs to the nudix hydrolase family
M3Y14_10805	COG0668	transmembrane transport
M3Y14_10810	COG2203	Gaf domain
M3Y14_10810	COG4585	Histidine kinase
M3Y14_10815	COG2197	response regulator
M3Y14_10820	COG1737	Transcriptional regulator
M3Y14_10825	COG1064	alcohol dehydrogenase
M3Y14_10840	COG1070	Carbohydrate kinase
M3Y14_10850	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
M3Y14_10885	COG1125	glycine betaine transport
M3Y14_10885	COG0517	IMP dehydrogenase activity
M3Y14_10890	COG1174	glycine betaine transport
M3Y14_10925	COG1253	flavin adenine dinucleotide binding
M3Y14_10930	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_10935	COG5506	Protein of unknown function (DUF1694)
M3Y14_10950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M3Y14_10955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M3Y14_10960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M3Y14_10965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M3Y14_10970	COG0456	acetyltransferase
M3Y14_10975	COG3829	transcription factor binding
M3Y14_10980	COG1509	lysine 2,3-aminomutase activity
M3Y14_10990	COG4479	Belongs to the UPF0346 family
M3Y14_11015	COG4991	sh3 domain protein
M3Y14_11015	COG0515	serine threonine protein kinase
M3Y14_11015	COG3064	Membrane
M3Y14_11025	COG0671	phosphoesterase, PA-phosphatase related
M3Y14_11030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M3Y14_11040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M3Y14_11045	COG0582	viral genome integration into host DNA
M3Y14_11060	COG5377	YqaJ viral recombinase family
M3Y14_11105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M3Y14_11125	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_11145	COG4499	WXG100 protein secretion system (Wss), protein YukC
M3Y14_11145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3Y14_11155	COG2814	Major facilitator Superfamily
M3Y14_11165	COG0372	Belongs to the citrate synthase family
M3Y14_11170	COG2079	MmgE PrpD family protein
M3Y14_11175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M3Y14_11180	COG1960	acyl-CoA dehydrogenase activity
M3Y14_11185	COG2084	Dehydrogenase
M3Y14_11190	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_11195	COG1280	lysine exporter protein (LysE YggA)
M3Y14_11200	COG1024	Enoyl-CoA hydratase
M3Y14_11215	COG0420	3'-5' exonuclease activity
M3Y14_11220	COG0419	ATPase involved in DNA repair
M3Y14_11230	COG3397	chitin binding
M3Y14_11235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M3Y14_11250	COG2223	nitrite transmembrane transporter activity
M3Y14_11255	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_11260	COG1169	isochorismate synthase
M3Y14_11265	COG1021	2,3-dihydroxybenzoate-AMP ligase
M3Y14_11270	COG1535	isochorismatase
M3Y14_11270	COG3433	isochorismatase activity
M3Y14_11275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M3Y14_11280	COG3251	PFAM MbtH domain protein
M3Y14_11285	COG2814	Major facilitator Superfamily
M3Y14_11300	COG0776	regulation of translation
M3Y14_11310	COG1115	amino acid carrier protein
M3Y14_11330	COG2329	Antibiotic biosynthesis monooxygenase
M3Y14_11335	COG1187	pseudouridine synthase activity
M3Y14_11340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M3Y14_11360	COG1136	(ABC) transporter
M3Y14_11370	COG0596	Alpha beta hydrolase
M3Y14_11375	COG2814	Major facilitator Superfamily
M3Y14_11390	COG0028	Belongs to the TPP enzyme family
M3Y14_11400	COG2226	methyltransferase
M3Y14_11405	COG1253	flavin adenine dinucleotide binding
M3Y14_11440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_11445	COG1309	transcriptional regulator
M3Y14_11475	COG1247	-acetyltransferase
M3Y14_11505	COG0596	Alpha beta hydrolase
M3Y14_11510	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M3Y14_11525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_11560	COG0561	phosphatase activity
M3Y14_11570	COG0583	DNA-binding transcription factor activity
M3Y14_11575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M3Y14_11595	COG0583	DNA-binding transcription factor activity
M3Y14_11600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M3Y14_11605	COG2258	MOSC domain
M3Y14_11615	COG1132	(ABC) transporter
M3Y14_11620	COG1132	(ABC) transporter
M3Y14_11635	COG1396	sequence-specific DNA binding
M3Y14_11675	COG1595	DNA-templated transcription, initiation
M3Y14_11700	COG1649	PFAM Uncharacterised BCR, COG1649
M3Y14_11725	COG2971	BadF BadG BcrA BcrD
M3Y14_11745	COG1846	Transcriptional regulator
M3Y14_11760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_11780	COG1309	transcriptional regulator
M3Y14_11795	COG1136	(ABC) transporter
M3Y14_11810	COG2226	methyltransferase
M3Y14_11815	COG2312	Erythromycin esterase
M3Y14_11860	COG2195	Cleaves the N-terminal amino acid of tripeptides
M3Y14_11880	COG1686	Belongs to the peptidase S11 family
M3Y14_11910	COG0768	penicillin binding
M3Y14_11915	COG1595	DNA-templated transcription, initiation
M3Y14_11925	COG0768	penicillin binding
M3Y14_11930	COG0768	penicillin binding
M3Y14_11960	COG1316	TRANSCRIPTIONal
M3Y14_11965	COG2239	Acts as a magnesium transporter
M3Y14_11970	COG0772	Belongs to the SEDS family
M3Y14_11980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M3Y14_11995	COG0697	spore germination
M3Y14_12025	COG3397	chitin binding
M3Y14_12040	COG1408	metallophosphoesterase
M3Y14_12050	COG1131	(ABC) transporter
M3Y14_12060	COG1309	transcriptional regulator
M3Y14_12070	COG1960	acyl-CoA dehydrogenase activity
M3Y14_12075	COG0439	Biotin carboxylase
M3Y14_12080	COG0511	ligase activity, forming carbon-carbon bonds
M3Y14_12085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M3Y14_12090	COG1024	Enoyl-CoA hydratase
M3Y14_12095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M3Y14_12100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M3Y14_12140	COG1686	Belongs to the peptidase S11 family
M3Y14_12165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M3Y14_12205	COG0577	efflux transmembrane transporter activity
M3Y14_12205	COG1136	(ABC) transporter
M3Y14_12215	COG0745	RESPONSE REGULATOR receiver
M3Y14_12220	COG5002	protein histidine kinase activity
M3Y14_12235	COG2207	Transcriptional regulator
M3Y14_12265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M3Y14_12285	COG0693	protein deglycase activity
M3Y14_12305	COG4978	Transcriptional regulator
M3Y14_12305	COG0789	Transcriptional regulator
M3Y14_12315	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_12320	COG1733	regulation of RNA biosynthetic process
M3Y14_12345	COG1309	transcriptional regulator
M3Y14_12375	COG0697	spore germination
M3Y14_12380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_12395	COG2368	4-hydroxyphenylacetate
M3Y14_12415	COG1063	alcohol dehydrogenase
M3Y14_12425	COG2323	membrane
M3Y14_12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_12445	COG0697	spore germination
M3Y14_12465	COG0201	protein transport
M3Y14_12495	COG1523	belongs to the glycosyl hydrolase 13 family
M3Y14_12500	COG1073	alpha beta
M3Y14_12505	COG1396	sequence-specific DNA binding
M3Y14_12550	COG0463	Glycosyl transferase, family 2
M3Y14_12585	COG2124	cytochrome p450
M3Y14_12620	COG0561	phosphatase activity
M3Y14_12625	COG5002	protein histidine kinase activity
M3Y14_12630	COG0768	penicillin binding
M3Y14_12640	COG1819	glycosyl
M3Y14_12645	COG1794	racemase activity, acting on amino acids and derivatives
M3Y14_12650	COG4720	Psort location CytoplasmicMembrane, score
M3Y14_12655	COG1122	ATPase activity
M3Y14_12670	COG2205	protein histidine kinase activity
M3Y14_12680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M3Y14_12690	COG0745	RESPONSE REGULATOR receiver
M3Y14_12695	COG5002	protein histidine kinase activity
M3Y14_12700	COG0604	alcohol dehydrogenase
M3Y14_12705	COG0671	phosphoesterase, PA-phosphatase related
M3Y14_12710	COG0768	penicillin binding
M3Y14_12755	COG2814	Major facilitator Superfamily
M3Y14_12760	COG0789	Transcriptional regulator
M3Y14_12760	COG4978	Transcriptional regulator
M3Y14_12780	COG0584	glycerophosphoryl diester phosphodiesterase
M3Y14_12800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_12805	COG0697	spore germination
M3Y14_12820	COG0494	nUDIX hydrolase
M3Y14_12830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M3Y14_12840	COG2223	nitrite transmembrane transporter activity
M3Y14_12850	COG0592	DNA-directed DNA polymerase activity
M3Y14_12855	COG1051	belongs to the nudix hydrolase family
M3Y14_12875	COG3878	Protein conserved in bacteria
M3Y14_12900	COG4667	esterase of the alpha-beta hydrolase superfamily
M3Y14_12915	COG2318	DinB family
M3Y14_12940	COG0322	excinuclease ABC activity
M3Y14_12960	COG3961	Belongs to the TPP enzyme family
M3Y14_12970	COG1132	(ABC) transporter
M3Y14_12980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M3Y14_12985	COG1183	phosphatidylcholine synthase activity
M3Y14_12990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3Y14_13015	COG1011	Hydrolase
M3Y14_13025	COG0745	RESPONSE REGULATOR receiver
M3Y14_13030	COG5002	protein histidine kinase activity
M3Y14_13065	COG1136	(ABC) transporter
M3Y14_13110	COG1484	DNA-dependent DNA replication
M3Y14_13140	COG1396	sequence-specific DNA binding
M3Y14_13155	COG0582	viral genome integration into host DNA
M3Y14_13165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M3Y14_13175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_13200	COG0577	efflux transmembrane transporter activity
M3Y14_13205	COG1136	(ABC) transporter
M3Y14_13220	COG0488	(ABC) transporter
M3Y14_13225	COG0667	Aldo Keto reductase
M3Y14_13230	COG0583	DNA-binding transcription factor activity
M3Y14_13250	COG2205	protein histidine kinase activity
M3Y14_13255	COG0745	RESPONSE REGULATOR receiver
M3Y14_13265	COG3773	Cell wall hydrolase
M3Y14_13270	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
M3Y14_13280	COG3386	PFAM SMP-30 Gluconolaconase
M3Y14_13320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_13335	COG2959	enzyme of heme biosynthesis
M3Y14_13370	COG3844	kynureninase activity
M3Y14_13375	COG1309	transcriptional regulator
M3Y14_13400	COG3284	Transcriptional regulator
M3Y14_13415	COG1349	DNA-binding transcription factor activity
M3Y14_13435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M3Y14_13440	COG0508	dehydrogenase complex catalyzes the overall conversion of
M3Y14_13445	COG0022	dehydrogenase e1 component
M3Y14_13450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M3Y14_13470	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_13475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M3Y14_13475	COG0456	acetyltransferase
M3Y14_13515	COG4176	ABC-type proline glycine betaine transport system permease component
M3Y14_13520	COG0517	IMP dehydrogenase activity
M3Y14_13520	COG4175	Glycine betaine
M3Y14_13545	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M3Y14_13550	COG2153	protein acetylation
M3Y14_13555	COG3397	chitin binding
M3Y14_13565	COG1819	glycosyl
M3Y14_13585	COG2205	protein histidine kinase activity
M3Y14_13590	COG2226	methyltransferase
M3Y14_13595	COG2315	Protein conserved in bacteria
M3Y14_13640	COG3973	AAA domain
M3Y14_13655	COG0514	ATP-dependent DNA helicase (RecQ)
M3Y14_13700	COG4637	Psort location Cytoplasmic, score
M3Y14_13710	COG1227	inorganic diphosphatase activity
M3Y14_13715	COG3397	chitin binding
M3Y14_13720	COG2318	DinB family
M3Y14_13740	COG1115	amino acid carrier protein
M3Y14_13745	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M3Y14_13760	COG3938	Belongs to the proline racemase family
M3Y14_13765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3Y14_13825	COG1078	dGTPase activity
M3Y14_13830	COG0586	Pfam SNARE associated Golgi protein
M3Y14_13845	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M3Y14_13850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_13855	COG4166	transmembrane transport
M3Y14_13865	COG4948	Mandelate Racemase Muconate Lactonizing
M3Y14_13880	COG0667	Aldo Keto reductase
M3Y14_13915	COG2936	dipeptidyl-peptidase activity
M3Y14_13925	COG0745	RESPONSE REGULATOR receiver
M3Y14_13945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M3Y14_13955	COG1164	Oligoendopeptidase f
M3Y14_13980	COG1307	EDD domain protein, DegV family
M3Y14_14035	COG2814	Major facilitator Superfamily
M3Y14_14045	COG1664	Polymer-forming cytoskeletal
M3Y14_14050	COG0789	Transcriptional regulator
M3Y14_14055	COG4533	DNA binding
M3Y14_14060	COG0477	Major facilitator Superfamily
M3Y14_14060	COG2814	Major facilitator Superfamily
M3Y14_14080	COG2261	transglycosylase associated protein
M3Y14_14095	COG2226	methyltransferase
M3Y14_14130	COG0436	Aminotransferase
M3Y14_14135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M3Y14_14145	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M3Y14_14160	COG1131	(ABC) transporter
M3Y14_14215	COG0628	permease
M3Y14_14225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M3Y14_14230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Y14_14235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Y14_14270	COG2746	aminoglycoside 3-N-acetyltransferase activity
M3Y14_14295	COG0697	spore germination
M3Y14_14315	COG4912	Dna alkylation repair
M3Y14_14365	COG2814	Major facilitator Superfamily
M3Y14_14370	COG1368	sulfuric ester hydrolase activity
M3Y14_14380	COG0488	(ABC) transporter
M3Y14_14385	COG2409	Drug exporters of the RND superfamily
M3Y14_14385	COG1033	growth of symbiont in host cell
M3Y14_14390	COG1309	transcriptional regulator
M3Y14_14405	COG0287	Prephenate dehydrogenase
M3Y14_14420	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M3Y14_14420	COG1605	Chorismate mutase
M3Y14_14465	COG0346	lactoylglutathione lyase activity
M3Y14_14500	COG1309	transcriptional regulator
M3Y14_14510	COG1595	DNA-templated transcription, initiation
M3Y14_14530	COG0579	oxidoreductase
M3Y14_14535	COG1879	ABC-type sugar transport system periplasmic component
M3Y14_14540	COG1172	Belongs to the binding-protein-dependent transport system permease family
M3Y14_14555	COG2390	Transcriptional regulator
M3Y14_14570	COG1830	Aldolase
M3Y14_14575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_14600	COG0346	lactoylglutathione lyase activity
M3Y14_14605	COG2329	Antibiotic biosynthesis monooxygenase
M3Y14_14625	COG1472	Belongs to the glycosyl hydrolase 3 family
M3Y14_14630	COG2207	Transcriptional regulator
M3Y14_14635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3Y14_14640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
M3Y14_14645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M3Y14_14650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M3Y14_14655	COG3239	Fatty acid desaturase
M3Y14_14670	COG3655	Transcriptional regulator
M3Y14_14675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3Y14_14675	COG4499	WXG100 protein secretion system (Wss), protein YukC
M3Y14_14740	COG1696	Membrane protein involved in D-alanine export
M3Y14_14760	COG5002	protein histidine kinase activity
M3Y14_14765	COG0745	RESPONSE REGULATOR receiver
M3Y14_14805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_14810	COG0346	lactoylglutathione lyase activity
M3Y14_14840	COG0714	Associated with various cellular activities
M3Y14_14865	COG0814	amino acid
M3Y14_14870	COG0697	spore germination
M3Y14_14875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M3Y14_14880	COG0753	catalase activity
M3Y14_14915	COG0778	Nitroreductase
M3Y14_14920	COG1846	Transcriptional regulator
M3Y14_14935	COG0494	nUDIX hydrolase
M3Y14_14940	COG3831	ATPase activity
M3Y14_14940	COG4884	unkown
M3Y14_14945	COG1136	(ABC) transporter
M3Y14_14980	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_14985	COG1309	transcriptional regulator
M3Y14_15020	COG0456	acetyltransferase
M3Y14_15035	COG0697	spore germination
M3Y14_15040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_15070	COG0456	acetyltransferase
M3Y14_15070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M3Y14_15095	COG0730	response to heat
M3Y14_15105	COG0833	amino acid
M3Y14_15140	COG0768	penicillin binding
M3Y14_15150	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
M3Y14_15165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
M3Y14_15170	COG1984	allophanate hydrolase subunit 2
M3Y14_15175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M3Y14_15180	COG1414	Transcriptional regulator
M3Y14_15200	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3Y14_15205	COG0640	Transcriptional regulator
M3Y14_15220	COG1960	acyl-CoA dehydrogenase activity
M3Y14_15245	COG0640	Transcriptional regulator
M3Y14_15250	COG3314	Sporulation integral membrane protein YlbJ
M3Y14_15270	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M3Y14_15290	COG3848	Pyruvate phosphate dikinase
M3Y14_15290	COG0574	Belongs to the PEP-utilizing enzyme family
M3Y14_15330	COG0745	RESPONSE REGULATOR receiver
M3Y14_15335	COG1136	(ABC) transporter
M3Y14_15340	COG0577	efflux transmembrane transporter activity
M3Y14_15370	COG2211	Major facilitator Superfamily
M3Y14_15380	COG0840	transmembrane signaling receptor activity
M3Y14_15385	COG1335	isochorismatase
M3Y14_15420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
M3Y14_15425	COG0730	response to heat
M3Y14_15460	COG1575	Belongs to the MenA family. Type 1 subfamily
M3Y14_15465	COG0803	Belongs to the bacterial solute-binding protein 9 family
M3Y14_15470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M3Y14_15475	COG1121	(ABC) transporter
M3Y14_15495	COG0798	PFAM Bile acid sodium symporter
M3Y14_15500	COG0346	lactoylglutathione lyase activity
M3Y14_15505	COG0640	Transcriptional regulator
M3Y14_15510	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_15515	COG1522	sequence-specific DNA binding
M3Y14_15530	COG0346	lactoylglutathione lyase activity
M3Y14_15535	COG3850	Histidine kinase
M3Y14_15535	COG5002	protein histidine kinase activity
M3Y14_15540	COG0745	RESPONSE REGULATOR receiver
M3Y14_15605	COG0384	phenazine biosynthesis protein PhzF
M3Y14_15610	COG2814	Major facilitator Superfamily
M3Y14_15620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M3Y14_15625	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M3Y14_15655	COG0789	Transcriptional regulator
M3Y14_15665	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M3Y14_15685	COG0277	FAD linked oxidase domain protein
M3Y14_15695	COG0577	efflux transmembrane transporter activity
M3Y14_15710	COG5002	protein histidine kinase activity
M3Y14_15710	COG3850	Histidine kinase
M3Y14_15725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_15805	COG4980	gas vesicle protein
M3Y14_15805	COG1674	ftsk spoiiie
M3Y14_15850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M3Y14_15860	COG1191	sigma factor activity
M3Y14_15910	COG3800	Transcriptional regulator
M3Y14_15910	COG1396	sequence-specific DNA binding
M3Y14_15930	COG1619	proteins homologs of microcin C7 resistance protein MccF
M3Y14_15945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M3Y14_16005	COG2814	Major facilitator Superfamily
M3Y14_16075	COG4282	regulation of fungal-type cell wall biogenesis
M3Y14_16125	COG0477	Major facilitator Superfamily
M3Y14_16135	COG1846	Transcriptional regulator
M3Y14_16140	COG2814	Major facilitator Superfamily
M3Y14_16175	COG2031	fatty acid transporter
M3Y14_16185	COG2249	NAD(P)H dehydrogenase (quinone) activity
M3Y14_16235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M3Y14_16240	COG1288	antiporter activity
M3Y14_16245	COG2356	endonuclease I
M3Y14_16255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M3Y14_16260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M3Y14_16295	COG1785	Belongs to the alkaline phosphatase family
M3Y14_16300	COG0778	Nitroreductase
M3Y14_16305	COG1733	regulation of RNA biosynthetic process
M3Y14_16330	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_16340	COG1131	(ABC) transporter
M3Y14_16370	COG1011	Hydrolase
M3Y14_16380	COG2365	Tyrosine phosphatase family
M3Y14_16405	COG0346	lactoylglutathione lyase activity
M3Y14_16410	COG1940	carbohydrate kinase activity
M3Y14_16415	COG0738	Major facilitator superfamily
M3Y14_16420	COG0110	maltose O-acetyltransferase activity
M3Y14_16460	COG0798	PFAM Bile acid sodium symporter
M3Y14_16465	COG0346	lactoylglutathione lyase activity
M3Y14_16470	COG0640	Transcriptional regulator
M3Y14_16475	COG0628	permease
M3Y14_16500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M3Y14_16510	COG0477	Major facilitator Superfamily
M3Y14_16520	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
M3Y14_16530	COG1253	flavin adenine dinucleotide binding
M3Y14_16535	COG0789	Transcriptional regulator
M3Y14_16540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M3Y14_16565	COG0697	spore germination
M3Y14_16575	COG1357	PFAM Pentapeptide repeats (8 copies)
M3Y14_16580	COG3813	Protein conserved in bacteria
M3Y14_16595	COG2706	6-phosphogluconolactonase activity
M3Y14_16600	COG1070	Carbohydrate kinase
M3Y14_16610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
M3Y14_16615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M3Y14_16620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M3Y14_16630	COG0604	alcohol dehydrogenase
M3Y14_16630	COG3321	synthase
M3Y14_16635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_16640	COG4702	Belongs to the UPF0303 family
M3Y14_16670	COG1733	regulation of RNA biosynthetic process
M3Y14_16675	COG2188	Transcriptional regulator
M3Y14_16680	COG0673	inositol 2-dehydrogenase activity
M3Y14_16710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_16740	COG0384	phenazine biosynthesis protein PhzF
M3Y14_16745	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_16755	COG0318	PFAM AMP-dependent synthetase and ligase
M3Y14_16760	COG2249	NAD(P)H dehydrogenase (quinone) activity
M3Y14_16765	COG1733	regulation of RNA biosynthetic process
M3Y14_16780	COG1191	sigma factor activity
M3Y14_16860	COG1151	hydroxylamine reductase activity
M3Y14_16870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_16900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M3Y14_16910	COG2072	flavoprotein involved in K transport
M3Y14_16955	COG1695	Transcriptional regulator
M3Y14_16960	COG0604	alcohol dehydrogenase
M3Y14_16965	COG1113	amino acid transport
M3Y14_16975	COG2814	Major facilitator Superfamily
M3Y14_16985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M3Y14_17000	COG0534	Mate efflux family protein
M3Y14_17005	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_17010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3Y14_17025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M3Y14_17030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M3Y14_17045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3Y14_17050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_17055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_17060	COG3739	integral membrane protein
M3Y14_17075	COG0583	DNA-binding transcription factor activity
M3Y14_17085	COG2890	protein-(glutamine-N5) methyltransferase activity
M3Y14_17100	COG1193	negative regulation of DNA recombination
M3Y14_17110	COG2162	N-hydroxyarylamine O-acetyltransferase activity
M3Y14_17115	COG1164	Oligoendopeptidase f
M3Y14_17140	COG3781	membrane
M3Y14_17155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M3Y14_17165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M3Y14_17170	COG0640	Transcriptional regulator
M3Y14_17175	COG0604	alcohol dehydrogenase
M3Y14_17180	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M3Y14_17185	COG0457	Tetratricopeptide repeat
M3Y14_17190	COG2808	Putative FMN-binding domain
M3Y14_17205	COG0277	FAD linked oxidase domain protein
M3Y14_17225	COG1285	pathogenesis
M3Y14_17235	COG2514	catechol 2,3-dioxygenase activity
M3Y14_17240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Y14_17245	COG1126	abc transporter atp-binding protein
M3Y14_17250	COG0765	amino acid transport
M3Y14_17255	COG2720	vancomycin resistance protein
M3Y14_17275	COG4451	ribulose bisphosphate carboxylase, small
M3Y14_17275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M3Y14_17295	COG1278	Cold shock
M3Y14_17305	COG0716	FMN binding
M3Y14_17345	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_17355	COG0165	Argininosuccinate lyase
M3Y14_17370	COG4145	pantothenate transmembrane transporter activity
M3Y14_17380	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_17385	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_17395	COG1657	PFAM Prenyltransferase squalene oxidase
M3Y14_17400	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M3Y14_17405	COG2962	Rard protein
M3Y14_17410	COG3326	Membrane
M3Y14_17415	COG0531	amino acid
M3Y14_17445	COG2226	methyltransferase
M3Y14_17450	COG4166	transmembrane transport
M3Y14_17455	COG4166	transmembrane transport
M3Y14_17460	COG4166	transmembrane transport
M3Y14_17470	COG1131	(ABC) transporter
M3Y14_17490	COG0673	inositol 2-dehydrogenase activity
M3Y14_17495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M3Y14_17500	COG0187	DNA topoisomerase II activity
M3Y14_17505	COG1832	CoA-binding protein
M3Y14_17510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M3Y14_17515	COG0745	RESPONSE REGULATOR receiver
M3Y14_17525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M3Y14_17525	COG1328	CTP reductase activity
M3Y14_17535	COG4841	protein insertion into membrane
M3Y14_17540	COG0824	Thioesterase
M3Y14_17575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M3Y14_17590	COG2274	protein secretion by the type I secretion system
M3Y14_17595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M3Y14_17625	COG2211	Major facilitator Superfamily
M3Y14_17635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M3Y14_17645	COG0457	Tetratricopeptide repeat
M3Y14_17650	COG0183	Belongs to the thiolase family
M3Y14_17655	COG0318	PFAM AMP-dependent synthetase and ligase
M3Y14_17660	COG1268	BioY protein
M3Y14_17665	COG0318	PFAM AMP-dependent synthetase and ligase
M3Y14_17770	COG2002	toxin-antitoxin pair type II binding
M3Y14_17805	COG3646	Phage regulatory protein
M3Y14_17805	COG3645	SOS response
M3Y14_17830	COG0582	viral genome integration into host DNA
M3Y14_17835	COG1396	sequence-specific DNA binding
M3Y14_17860	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
M3Y14_17880	COG0830	nickel cation binding
M3Y14_17920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_17930	COG5002	protein histidine kinase activity
M3Y14_17940	COG0400	carboxylic ester hydrolase activity
M3Y14_17945	COG0346	lactoylglutathione lyase activity
M3Y14_17950	COG0069	glutamate synthase activity
M3Y14_17955	COG1902	pentaerythritol trinitrate reductase activity
M3Y14_17960	COG1329	Transcriptional regulator
M3Y14_17965	COG0010	Belongs to the arginase family
M3Y14_17975	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
M3Y14_17980	COG2986	histidine ammonia-lyase
M3Y14_17990	COG2226	methyltransferase
M3Y14_18015	COG4846	Membrane protein involved in cytochrome C biogenesis
M3Y14_18020	COG0785	Cytochrome C biogenesis protein
M3Y14_18030	COG1473	amidohydrolase
M3Y14_18040	COG1131	(ABC) transporter
M3Y14_18050	COG0583	DNA-binding transcription factor activity
M3Y14_18060	COG1346	cytolysis
M3Y14_18075	COG0730	response to heat
M3Y14_18100	COG1132	(ABC) transporter
M3Y14_18105	COG1132	(ABC) transporter
M3Y14_18110	COG3763	UPF0154 protein
M3Y14_18130	COG3639	organic phosphonate transmembrane transporter activity
M3Y14_18140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Y14_18145	COG0737	Belongs to the 5'-nucleotidase family
M3Y14_18155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M3Y14_18160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M3Y14_18175	COG1695	Transcriptional regulator
M3Y14_18185	COG0174	glutamine synthetase
M3Y14_18190	COG0789	Transcriptional regulator
M3Y14_18195	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M3Y14_18200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M3Y14_18205	COG2860	membrane
M3Y14_18215	COG0464	growth
M3Y14_18250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
M3Y14_18260	COG3584	3D domain protein
M3Y14_18260	COG1388	LysM domain
M3Y14_18265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M3Y14_18265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M3Y14_18265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M3Y14_18270	COG1105	Belongs to the carbohydrate kinase PfkB family
M3Y14_18275	COG1349	DNA-binding transcription factor activity
M3Y14_18280	COG1979	alcohol dehydrogenase
M3Y14_18285	COG2322	membrane
M3Y14_18295	COG1113	amino acid transport
M3Y14_18305	COG1473	amidohydrolase
M3Y14_18310	COG1408	metallophosphoesterase
M3Y14_18315	COG2116	formate transmembrane transporter activity
M3Y14_18325	COG0454	-acetyltransferase
M3Y14_18330	COG2217	Heavy metal translocating P-type atpase
M3Y14_18340	COG1937	Protein conserved in bacteria
M3Y14_18370	COG2819	hydrolase of the alpha beta superfamily
M3Y14_18375	COG1120	ATPase activity
M3Y14_18380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_18385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_18390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3Y14_18395	COG0708	Exodeoxyribonuclease III
M3Y14_18400	COG2169	Transcriptional regulator
M3Y14_18405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M3Y14_18410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M3Y14_18415	COG2195	Cleaves the N-terminal amino acid of tripeptides
M3Y14_18420	COG2364	Membrane
M3Y14_18435	COG2267	carboxylic ester hydrolase activity
M3Y14_18440	COG0346	lactoylglutathione lyase activity
M3Y14_18445	COG3300	MHYT domain
M3Y14_18445	COG5001	Diguanylate cyclase
M3Y14_18485	COG1346	cytolysis
M3Y14_18495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_18500	COG2945	thiolester hydrolase activity
M3Y14_18500	COG0596	Alpha beta hydrolase
M3Y14_18505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M3Y14_18515	COG2188	Transcriptional regulator
M3Y14_18520	COG2723	6-phospho-beta-galactosidase activity
M3Y14_18530	COG3773	Cell wall hydrolase
M3Y14_18540	COG1368	sulfuric ester hydrolase activity
M3Y14_18555	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M3Y14_18560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M3Y14_18575	COG4550	Control of competence regulator ComK, YlbF/YmcA
M3Y14_18580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M3Y14_18585	COG1013	pyruvate-flavodoxin oxidoreductase activity
M3Y14_18590	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M3Y14_18590	COG0674	pyruvate-flavodoxin oxidoreductase activity
M3Y14_18600	COG2359	stage V sporulation protein S
M3Y14_18605	COG1692	metallophosphoesterase
M3Y14_18610	COG1418	mRNA catabolic process
M3Y14_18615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M3Y14_18620	COG1546	Belongs to the CinA family
M3Y14_18620	COG1058	Belongs to the CinA family
M3Y14_18625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M3Y14_18630	COG1426	Protein conserved in bacteria
M3Y14_18645	COG0300	oxidoreductase activity
M3Y14_18650	COG0612	Peptidase, M16
M3Y14_18655	COG0612	Peptidase, M16
M3Y14_18660	COG1079	Belongs to the binding-protein-dependent transport system permease family
M3Y14_18665	COG4603	Belongs to the binding-protein-dependent transport system permease family
M3Y14_18670	COG3845	ABC transporter
M3Y14_18675	COG1744	ABC transporter substrate-binding protein PnrA-like
M3Y14_18680	COG2188	Transcriptional regulator
M3Y14_18685	COG1674	ftsk spoiiie
M3Y14_18695	COG0740	serine-type endopeptidase activity
M3Y14_18700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M3Y14_18710	COG0527	aspartate kinase activity
M3Y14_18715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M3Y14_18770	COG0305	Participates in initiation and elongation during chromosome replication
M3Y14_18810	COG1396	sequence-specific DNA binding
M3Y14_18850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M3Y14_18855	COG1873	PFAM PRC-barrel domain
M3Y14_18860	COG0612	Peptidase, M16
M3Y14_18865	COG0726	polysaccharide deacetylase
M3Y14_18870	COG1185	polyribonucleotide nucleotidyltransferase activity
M3Y14_18880	COG0196	riboflavin kinase activity
M3Y14_18890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
M3Y14_18895	COG1550	Protein conserved in bacteria
M3Y14_18900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
M3Y14_18905	COG1358	cellular component organization or biogenesis
M3Y14_18910	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M3Y14_18915	COG0195	Participates in both transcription termination and antitermination
M3Y14_18920	COG0779	Required for maturation of 30S ribosomal subunits
M3Y14_18930	COG0442	prolyl-tRNA aminoacylation
M3Y14_18935	COG0750	zinc metalloprotease
M3Y14_18945	COG4589	Belongs to the CDS family
M3Y14_18955	COG0233	cytoplasmic translational termination
M3Y14_18960	COG0528	UMP kinase activity
M3Y14_18965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
M3Y14_18975	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M3Y14_18980	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
M3Y14_18985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
M3Y14_18990	COG4974	Belongs to the 'phage' integrase family
M3Y14_18995	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
M3Y14_19000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M3Y14_19005	COG0758	DNA mediated transformation
M3Y14_19010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M3Y14_19015	COG0045	succinate-CoA ligase (ADP-forming) activity
M3Y14_19020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M3Y14_19035	COG0335	large ribosomal subunit rRNA binding
M3Y14_19040	COG0336	Belongs to the RNA methyltransferase TrmD family
M3Y14_19045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M3Y14_19050	COG1837	Belongs to the UPF0109 family
M3Y14_19060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M3Y14_19070	COG0552	protein localization to endoplasmic reticulum
M3Y14_19075	COG1196	nuclear chromosome segregation
M3Y14_19080	COG0571	ribonuclease III activity
M3Y14_19085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3Y14_19090	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_19095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M3Y14_19110	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M3Y14_19115	COG1461	Dihydroxyacetone kinase
M3Y14_19120	COG1302	Protein conserved in bacteria
M3Y14_19135	COG1564	THIamine pyrophosphokinase
M3Y14_19140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M3Y14_19150	COG2815	serine threonine protein kinase
M3Y14_19150	COG0515	serine threonine protein kinase
M3Y14_19155	COG0631	protein serine/threonine phosphatase activity
M3Y14_19160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
M3Y14_19165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M3Y14_19165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M3Y14_19170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M3Y14_19175	COG0242	peptide deformylase activity
M3Y14_19180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M3Y14_19185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M3Y14_19190	COG1758	RNA polymerase activity
M3Y14_19205	COG1561	YicC-like family, N-terminal region
M3Y14_19210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M3Y14_19225	COG0006	proline dipeptidase activity
M3Y14_19245	COG3069	C4-dicarboxylate transmembrane transporter activity
M3Y14_19245	COG3069	C4-dicarboxylate transmembrane transporter activity
M3Y14_19305	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
M3Y14_19310	COG0564	pseudouridine synthase activity
M3Y14_19330	COG3599	regulation of cell shape
M3Y14_19335	COG2302	S4 RNA-binding domain
M3Y14_19340	COG0762	integral membrane protein
M3Y14_19345	COG1799	cell septum assembly
M3Y14_19350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M3Y14_19360	COG1873	PFAM PRC-barrel domain
M3Y14_19365	COG1191	sigma factor activity
M3Y14_19370	COG1191	sigma factor activity
M3Y14_19380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M3Y14_19385	COG0849	cell division
M3Y14_19390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M3Y14_19405	COG0772	Belongs to the SEDS family
M3Y14_19410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M3Y14_19415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M3Y14_19420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M3Y14_19425	COG0768	penicillin binding
M3Y14_19430	COG0768	penicillin binding
M3Y14_19440	COG0275	rRNA processing
M3Y14_19445	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
M3Y14_19450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M3Y14_19455	COG0454	-acetyltransferase
M3Y14_19465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M3Y14_19470	COG1399	metal-binding, possibly nucleic acid-binding protein
M3Y14_19535	COG2002	toxin-antitoxin pair type II binding
M3Y14_19545	COG1484	DNA-dependent DNA replication
M3Y14_19575	COG3620	sequence-specific DNA binding
M3Y14_19595	COG1395	domain, Protein
M3Y14_19610	COG0582	viral genome integration into host DNA
M3Y14_19615	COG1323	Belongs to the UPF0348 family
M3Y14_19620	COG3480	Lon protease (S16) C-terminal proteolytic domain
M3Y14_19625	COG1752	Esterase of the alpha-beta hydrolase superfamily
M3Y14_19630	COG3314	Sporulation integral membrane protein YlbJ
M3Y14_19640	COG0742	ribosomal rna small subunit methyltransferase
M3Y14_19650	COG4471	UPF0298 protein
M3Y14_19655	COG3679	Belongs to the UPF0342 family
M3Y14_19660	COG0406	alpha-ribazole phosphatase activity
M3Y14_19675	COG2340	Cysteine-rich secretory protein family
M3Y14_19690	COG3336	cytochrome c oxidase
M3Y14_19715	COG0109	protoheme IX farnesyltransferase activity
M3Y14_19720	COG1612	heme a metabolic process
M3Y14_19725	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M3Y14_19730	COG0772	Belongs to the SEDS family
M3Y14_19735	COG4838	Belongs to the UPF0358 family
M3Y14_19740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M3Y14_19745	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M3Y14_19755	COG4896	Protein conserved in bacteria
M3Y14_19770	COG1217	gtp-binding protein TYPA
M3Y14_19780	COG0483	inositol monophosphate 1-phosphatase activity
M3Y14_19790	COG4493	Belongs to the UPF0637 family
M3Y14_19795	COG4476	Belongs to the UPF0223 family
M3Y14_19800	COG1982	Orn Lys Arg decarboxylase major
M3Y14_19850	COG0022	dehydrogenase e1 component
M3Y14_19855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M3Y14_19870	COG0561	phosphatase activity
M3Y14_19875	COG5503	Protein of unknown function (DUF1447)
M3Y14_19880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M3Y14_19885	COG0569	domain protein
M3Y14_19895	COG1473	amidohydrolase
M3Y14_19900	COG2171	N-acyltransferase activity
M3Y14_19905	COG0583	DNA-binding transcription factor activity
M3Y14_19910	COG0517	IMP dehydrogenase activity
M3Y14_19920	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M3Y14_19930	COG4703	Protein of unknown function (DUF1797)
M3Y14_19945	COG2200	EAL domain
M3Y14_19950	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_19955	COG1408	metallophosphoesterase
M3Y14_20000	COG2814	Major facilitator Superfamily
M3Y14_20010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M3Y14_20020	COG3209	COG3209 Rhs family protein
M3Y14_20030	COG2205	protein histidine kinase activity
M3Y14_20040	COG0436	Aminotransferase
M3Y14_20045	COG1609	Transcriptional regulator
M3Y14_20050	COG3833	ABC-type maltose transport systems, permease component
M3Y14_20055	COG1175	transmembrane transport
M3Y14_20060	COG2182	Extracellular solute-binding protein
M3Y14_20070	COG0366	Alpha amylase catalytic
M3Y14_20075	COG3842	ATPase activity
M3Y14_20115	COG0183	Belongs to the thiolase family
M3Y14_20150	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_20160	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
M3Y14_20165	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
M3Y14_20170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M3Y14_20175	COG0436	Aminotransferase
M3Y14_20185	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
M3Y14_20190	COG0235	Class ii aldolase
M3Y14_20195	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
M3Y14_20210	COG2084	Dehydrogenase
M3Y14_20220	COG2199	diguanylate cyclase activity
M3Y14_20225	COG0778	Nitroreductase
M3Y14_20250	COG2190	(PTS) system
M3Y14_20250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3Y14_20250	COG1263	PTS System
M3Y14_20255	COG3711	transcriptional antiterminator
M3Y14_20265	COG2188	Transcriptional regulator
M3Y14_20270	COG0363	glucosamine-6-phosphate deaminase activity
M3Y14_20285	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M3Y14_20290	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M3Y14_20300	COG1547	Domain of unknown function (DUF309)
M3Y14_20310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M3Y14_20315	COG4086	secreted protein
M3Y14_20320	COG0561	phosphatase activity
M3Y14_20325	COG0697	spore germination
M3Y14_20340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M3Y14_20380	COG1686	Belongs to the peptidase S11 family
M3Y14_20385	COG1725	Transcriptional regulator
M3Y14_20390	COG1131	(ABC) transporter
M3Y14_20415	COG1846	Transcriptional regulator
M3Y14_20430	COG0598	Magnesium transport protein CorA
M3Y14_20455	COG4974	Belongs to the 'phage' integrase family
M3Y14_20465	COG0735	belongs to the Fur family
M3Y14_20470	COG1300	Membrane
M3Y14_20490	COG0667	Aldo Keto reductase
M3Y14_20495	COG0656	L-ascorbic acid biosynthetic process
M3Y14_20500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M3Y14_20500	COG0456	acetyltransferase
M3Y14_20510	COG0737	Belongs to the 5'-nucleotidase family
M3Y14_20510	COG1525	nuclease
M3Y14_20510	COG4085	toxin activity
M3Y14_20525	COG0596	Alpha beta hydrolase
M3Y14_20530	COG2056	Na+-H+ antiporter family
M3Y14_20535	COG1609	Transcriptional regulator
M3Y14_20540	COG0456	acetyltransferase
M3Y14_20545	COG1073	alpha beta
M3Y14_20560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M3Y14_20560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M3Y14_20565	COG0307	riboflavin synthase, alpha
M3Y14_20570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M3Y14_20570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M3Y14_20585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
M3Y14_20595	COG1073	alpha beta
M3Y14_20595	COG2226	methyltransferase
M3Y14_20600	COG0156	8-amino-7-oxononanoate synthase activity
M3Y14_20610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M3Y14_20620	COG1757	Na H antiporter
M3Y14_20625	COG0737	Belongs to the 5'-nucleotidase family
M3Y14_20635	COG1522	sequence-specific DNA binding
M3Y14_20655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M3Y14_20680	COG0300	oxidoreductase activity
M3Y14_20685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_20690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M3Y14_20695	COG1760	l-serine dehydratase
M3Y14_20700	COG1760	l-serine dehydratase
M3Y14_20715	COG1234	tRNA 3'-trailer cleavage
M3Y14_20730	COG1285	pathogenesis
M3Y14_20745	COG2195	Cleaves the N-terminal amino acid of tripeptides
M3Y14_20750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_20765	COG1376	ErfK ybiS ycfS ynhG family protein
M3Y14_20770	COG4129	membrane
M3Y14_20775	COG1126	abc transporter atp-binding protein
M3Y14_20780	COG0765	amino acid transport
M3Y14_20785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3Y14_20800	COG2816	NAD+ diphosphatase activity
M3Y14_20805	COG2323	membrane
M3Y14_20810	COG0772	Belongs to the SEDS family
M3Y14_20815	COG0508	dehydrogenase complex catalyzes the overall conversion of
M3Y14_20820	COG0022	dehydrogenase e1 component
M3Y14_20825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M3Y14_20830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M3Y14_20835	COG3426	butyrate kinase activity
M3Y14_20845	COG0280	phosphate acetyltransferase
M3Y14_20850	COG3829	transcription factor binding
M3Y14_20850	COG3290	protein histidine kinase activity
M3Y14_20860	COG0584	glycerophosphoryl diester phosphodiesterase
M3Y14_20865	COG3093	addiction module antidote protein HigA
M3Y14_20870	COG0745	RESPONSE REGULATOR receiver
M3Y14_20875	COG0750	zinc metalloprotease
M3Y14_20880	COG0497	DNA recombination
M3Y14_20885	COG1438	arginine binding
M3Y14_20890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M3Y14_20895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
M3Y14_20900	COG0142	geranyltranstransferase activity
M3Y14_20905	COG1722	exodeoxyribonuclease VII activity
M3Y14_20910	COG1570	exodeoxyribonuclease VII activity
M3Y14_20915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
M3Y14_20920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M3Y14_20925	COG1302	Protein conserved in bacteria
M3Y14_20930	COG0439	Biotin carboxylase
M3Y14_20935	COG0511	ligase activity, forming carbon-carbon bonds
M3Y14_20980	COG3854	ATPases associated with a variety of cellular activities
M3Y14_21000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
M3Y14_21005	COG0006	proline dipeptidase activity
M3Y14_21020	COG3872	metal-dependent enzyme
M3Y14_21030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M3Y14_21065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3Y14_21075	COG1609	Transcriptional regulator
M3Y14_21085	COG2076	Multidrug Resistance protein
M3Y14_21090	COG2076	Multidrug Resistance protein
M3Y14_21130	COG1725	Transcriptional regulator
M3Y14_21145	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M3Y14_21150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M3Y14_21155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
M3Y14_21160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M3Y14_21190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
M3Y14_21215	COG4970	Tfp pilus assembly protein FimT
M3Y14_21225	COG1459	type II secretion system
M3Y14_21230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M3Y14_21285	COG0646	methionine synthase
M3Y14_21285	COG1410	methionine synthase
M3Y14_21290	COG0646	methionine synthase
M3Y14_21290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M3Y14_21295	COG0626	cystathionine gamma-synthase activity
M3Y14_21300	COG0626	cystathionine gamma-synthase activity
M3Y14_21320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_21330	COG1940	carbohydrate kinase activity
M3Y14_21335	COG4483	Protein conserved in bacteria
M3Y14_21340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M3Y14_21345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M3Y14_21350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M3Y14_21355	COG0704	Plays a role in the regulation of phosphate uptake
M3Y14_21365	COG0581	inorganic phosphate transmembrane transporter activity
M3Y14_21370	COG0573	inorganic phosphate transmembrane transporter activity
M3Y14_21375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M3Y14_21380	COG0768	penicillin binding
M3Y14_21385	COG0477	Major facilitator Superfamily
M3Y14_21390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M3Y14_21410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
M3Y14_21415	COG0735	belongs to the Fur family
M3Y14_21420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M3Y14_21425	COG1121	(ABC) transporter
M3Y14_21430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_21440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
M3Y14_21460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M3Y14_21465	COG2384	SAM-dependent methyltransferase
M3Y14_21470	COG2010	Cytochrome c
M3Y14_21475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M3Y14_21480	COG0358	DNA primase activity
M3Y14_21485	COG1671	Belongs to the UPF0178 family
M3Y14_21490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
M3Y14_21495	COG0517	IMP dehydrogenase activity
M3Y14_21500	COG1381	Involved in DNA repair and RecF pathway recombination
M3Y14_21510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M3Y14_21515	COG0295	cytidine deaminase activity
M3Y14_21530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
M3Y14_21535	COG1480	7TM receptor with intracellular HD hydrolase
M3Y14_21540	COG1702	phosphate starvation-inducible protein PhoH
M3Y14_21555	COG1610	YqeY-like protein
M3Y14_21560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M3Y14_21570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M3Y14_21575	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M3Y14_21585	COG0484	heat shock protein binding
M3Y14_21590	COG0443	Heat shock 70 kDa protein
M3Y14_21600	COG1420	regulation of RNA biosynthetic process
M3Y14_21605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M3Y14_21610	COG1733	regulation of RNA biosynthetic process
M3Y14_21615	COG0481	GTPase activity
M3Y14_21625	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
M3Y14_21630	COG0268	Binds directly to 16S ribosomal RNA
M3Y14_21635	COG1466	dna polymerase III delta subunit
M3Y14_21645	COG2333	competence protein COMEC
M3Y14_21645	COG0658	competence protein
M3Y14_21650	COG2131	deaminase
M3Y14_21655	COG1555	photosystem II stabilization
M3Y14_21655	COG1596	polysaccharide export
M3Y14_21660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M3Y14_21665	COG2226	methyltransferase
M3Y14_21670	COG0799	negative regulation of ribosome biogenesis
M3Y14_21675	COG1713	HD superfamily hydrolase involved in NAD metabolism
M3Y14_21680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
M3Y14_21685	COG1534	Rna-binding protein
M3Y14_21690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M3Y14_21695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M3Y14_21700	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M3Y14_21710	COG0688	phosphatidylethanolamine metabolic process
M3Y14_21730	COG2357	RelA SpoT domain protein
M3Y14_21740	COG1785	Belongs to the alkaline phosphatase family
M3Y14_21750	COG2267	carboxylic ester hydrolase activity
M3Y14_21785	COG1404	Belongs to the peptidase S8 family
M3Y14_21790	COG3186	Phenylalanine-4-hydroxylase
M3Y14_21795	COG2154	pterin-4-alpha-carbinolamine dehydratase
M3Y14_21805	COG2514	catechol 2,3-dioxygenase activity
M3Y14_21810	COG2259	Doxx family
M3Y14_21850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M3Y14_21860	COG1012	belongs to the aldehyde dehydrogenase family
M3Y14_21860	COG1454	alcohol dehydrogenase
M3Y14_21865	COG0626	cystathionine gamma-synthase activity
M3Y14_21870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M3Y14_21875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M3Y14_21880	COG2226	methyltransferase
M3Y14_21895	COG0768	penicillin binding
M3Y14_21905	COG0572	uridine kinase
M3Y14_21910	COG0826	peptidase U32
M3Y14_21915	COG0826	peptidase U32
M3Y14_21920	COG4122	O-methyltransferase activity
M3Y14_21925	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M3Y14_21935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M3Y14_21945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M3Y14_21955	COG0628	permease
M3Y14_21975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M3Y14_21985	COG0482	sulfurtransferase activity
M3Y14_21990	COG1104	cysteine desulfurase activity
M3Y14_21995	COG1959	2 iron, 2 sulfur cluster binding
M3Y14_22000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M3Y14_22010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M3Y14_22045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M3Y14_22050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M3Y14_22055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M3Y14_22055	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M3Y14_22060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M3Y14_22065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M3Y14_22065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M3Y14_22075	COG2244	polysaccharide biosynthetic process
M3Y14_22080	COG2323	membrane
M3Y14_22090	COG1862	Preprotein translocase
M3Y14_22110	COG2255	four-way junction helicase activity
M3Y14_22115	COG0632	four-way junction helicase activity
M3Y14_22120	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M3Y14_22130	COG0697	spore germination
M3Y14_22135	COG0640	Transcriptional regulator
M3Y14_22155	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M3Y14_22160	COG0157	Belongs to the NadC ModD family
M3Y14_22165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M3Y14_22170	COG1104	cysteine desulfurase activity
M3Y14_22175	COG1827	regulation of RNA biosynthetic process
M3Y14_22180	COG2258	MOSC domain
M3Y14_22185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_22190	COG0077	Prephenate dehydratase
M3Y14_22195	COG0577	efflux transmembrane transporter activity
M3Y14_22200	COG0577	efflux transmembrane transporter activity
M3Y14_22205	COG1136	(ABC) transporter
M3Y14_22210	COG5002	protein histidine kinase activity
M3Y14_22215	COG0745	RESPONSE REGULATOR receiver
M3Y14_22220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M3Y14_22225	COG3290	protein histidine kinase activity
M3Y14_22235	COG2868	ribosomal protein
M3Y14_22245	COG1530	ribonuclease E activity
M3Y14_22250	COG1994	Peptidase M50
M3Y14_22255	COG0739	heme binding
M3Y14_22260	COG2894	cell division
M3Y14_22265	COG0850	regulation of cytokinetic process
M3Y14_22280	COG1077	Cell shape determining protein MreB Mrl
M3Y14_22285	COG2003	Belongs to the UPF0758 family
M3Y14_22290	COG0424	maF-like protein
M3Y14_22300	COG0285	dihydrofolate synthase activity
M3Y14_22315	COG1388	LysM domain
M3Y14_22320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
M3Y14_22325	COG0113	porphobilinogen synthase activity
M3Y14_22330	COG1587	Uroporphyrinogen-III synthase
M3Y14_22335	COG0181	hydroxymethylbilane synthase activity
M3Y14_22340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M3Y14_22345	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
M3Y14_22350	COG1846	Transcriptional regulator
M3Y14_22355	COG1764	response to oxidative stress
M3Y14_22360	COG0218	Necessary for normal cell division and for the maintenance of normal septation
M3Y14_22370	COG0470	DNA polymerase III
M3Y14_22370	COG1067	ATP-dependent peptidase activity
M3Y14_22380	COG0544	peptidyl-prolyl cis-trans isomerase activity
M3Y14_22415	COG0622	Phosphoesterase
M3Y14_22425	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
M3Y14_22430	COG5401	PFAM Sporulation and spore germination
M3Y14_22440	COG2197	response regulator
M3Y14_22445	COG2233	PERMEase
M3Y14_22450	COG0402	S-adenosylhomocysteine deaminase activity
M3Y14_22455	COG1983	PspC domain protein
M3Y14_22460	COG1396	sequence-specific DNA binding
M3Y14_22465	COG0697	spore germination
M3Y14_22475	COG1959	2 iron, 2 sulfur cluster binding
M3Y14_22480	COG1668	transmembrane transport
M3Y14_22485	COG4152	abc transporter atp-binding protein
M3Y14_22490	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
M3Y14_22495	COG1360	Flagellar Motor Protein
M3Y14_22500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M3Y14_22505	COG1876	peptidase activity
M3Y14_22510	COG0824	Thioesterase
M3Y14_22515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M3Y14_22520	COG1053	succinate dehydrogenase
M3Y14_22525	COG2009	succinate dehydrogenase
M3Y14_22530	COG1719	4-vinyl reductase, 4VR
M3Y14_22535	COG0322	excinuclease ABC activity
M3Y14_22540	COG3118	belongs to the thioredoxin family
M3Y14_22545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M3Y14_22550	COG2086	electron transfer activity
M3Y14_22555	COG1024	Enoyl-CoA hydratase
M3Y14_22560	COG1309	transcriptional regulator
M3Y14_22565	COG0318	PFAM AMP-dependent synthetase and ligase
M3Y14_22575	COG2318	DinB family
M3Y14_22605	COG1131	(ABC) transporter
M3Y14_22610	COG2205	protein histidine kinase activity
M3Y14_22615	COG0745	RESPONSE REGULATOR receiver
M3Y14_22625	COG4895	conserved protein (DUF2196)
M3Y14_22630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M3Y14_22640	COG4509	Sortase family
M3Y14_22645	COG1120	ATPase activity
M3Y14_22660	COG5386	Cell surface protein
M3Y14_22670	COG5386	Cell surface protein
M3Y14_22675	COG1114	Component of the transport system for branched-chain amino acids
M3Y14_22685	COG1193	negative regulation of DNA recombination
M3Y14_22690	COG1796	DNA polymerase
M3Y14_22690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M3Y14_22695	COG1286	toxin biosynthetic process
M3Y14_22700	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
M3Y14_22705	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M3Y14_22725	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_22740	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M3Y14_22745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M3Y14_22755	COG1418	mRNA catabolic process
M3Y14_22775	COG2814	Major facilitator Superfamily
M3Y14_22780	COG1566	PFAM secretion protein HlyD family protein
M3Y14_22785	COG1309	transcriptional regulator
M3Y14_22790	COG1363	Peptidase, m42
M3Y14_22800	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
M3Y14_22815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M3Y14_22825	COG1484	DNA-dependent DNA replication
M3Y14_22830	COG3611	Membrane attachment protein
M3Y14_22835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M3Y14_22840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M3Y14_22845	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M3Y14_22855	COG1971	Probably functions as a manganese efflux pump
M3Y14_22865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M3Y14_22865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M3Y14_22870	COG5002	protein histidine kinase activity
M3Y14_22875	COG0745	RESPONSE REGULATOR receiver
M3Y14_22895	COG0538	isocitrate dehydrogenase activity
M3Y14_22900	COG0372	Belongs to the citrate synthase family
M3Y14_22910	COG0628	permease
M3Y14_22915	COG3030	protein affecting phage T7 exclusion by the F plasmid
M3Y14_22925	COG0205	6-phosphofructokinase activity
M3Y14_22935	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
M3Y14_22940	COG1725	Transcriptional regulator
M3Y14_22945	COG0281	malic enzyme
M3Y14_22950	COG0587	DNA-directed DNA polymerase activity
M3Y14_22965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M3Y14_22980	COG4109	DRTGG domain
M3Y14_22995	COG0006	proline dipeptidase activity
M3Y14_23035	COG0662	Cupin 2, conserved barrel domain protein
M3Y14_23050	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_23055	COG0589	response to stress
M3Y14_23075	COG0165	Argininosuccinate lyase
M3Y14_23080	COG0137	argininosuccinate synthase activity
M3Y14_23095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_23115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M3Y14_23120	COG0827	DNA restriction-modification system
M3Y14_23125	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M3Y14_23130	COG3874	Sporulation protein YtfJ
M3Y14_23145	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M3Y14_23155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M3Y14_23170	COG1104	cysteine desulfurase activity
M3Y14_23175	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
M3Y14_23180	COG0583	DNA-binding transcription factor activity
M3Y14_23185	COG0697	spore germination
M3Y14_23190	COG1309	transcriptional regulator
M3Y14_23195	COG1956	GAF domain-containing protein
M3Y14_23200	COG0626	cystathionine gamma-synthase activity
M3Y14_23205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M3Y14_23230	COG1595	DNA-templated transcription, initiation
M3Y14_23240	COG0110	maltose O-acetyltransferase activity
M3Y14_23245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M3Y14_23250	COG0454	-acetyltransferase
M3Y14_23255	COG0517	IMP dehydrogenase activity
M3Y14_23260	COG0123	including yeast histone deacetylase and acetoin utilization protein
M3Y14_23265	COG2267	carboxylic ester hydrolase activity
M3Y14_23280	COG0673	inositol 2-dehydrogenase activity
M3Y14_23285	COG1970	mechanosensitive ion channel activity
M3Y14_23305	COG1609	Transcriptional regulator
M3Y14_23310	COG4851	CamS sex pheromone cAM373 precursor
M3Y14_23315	COG3118	belongs to the thioredoxin family
M3Y14_23325	COG2309	aminopeptidase activity
M3Y14_23350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_23355	COG0697	spore germination
M3Y14_23360	COG0789	Transcriptional regulator
M3Y14_23365	COG1695	Transcriptional regulator
M3Y14_23375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M3Y14_23400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M3Y14_23405	COG4848	Belongs to the UPF0354 family
M3Y14_23410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M3Y14_23415	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
M3Y14_23420	COG1363	Peptidase, m42
M3Y14_23430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_23435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M3Y14_23445	COG0510	thiamine kinase activity
M3Y14_23450	COG1523	belongs to the glycosyl hydrolase 13 family
M3Y14_23460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M3Y14_23465	COG1349	DNA-binding transcription factor activity
M3Y14_23470	COG1187	pseudouridine synthase activity
M3Y14_23475	COG2244	polysaccharide biosynthetic process
M3Y14_23480	COG2081	HI0933 family
M3Y14_23485	COG2814	Major facilitator Superfamily
M3Y14_23495	COG3832	glyoxalase III activity
M3Y14_23515	COG1329	Transcriptional regulator
M3Y14_23540	COG0314	molybdopterin synthase activity
M3Y14_23545	COG1763	Mo-molybdopterin cofactor biosynthetic process
M3Y14_23550	COG0303	'Molybdopterin
M3Y14_23555	COG0315	cyclic pyranopterin monophosphate synthase activity
M3Y14_23560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M3Y14_23565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M3Y14_23590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3Y14_23600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M3Y14_23645	COG2814	Major facilitator Superfamily
M3Y14_23650	COG0475	glutathione-regulated potassium exporter activity
M3Y14_23655	COG0490	domain, Protein
M3Y14_23660	COG0582	viral genome integration into host DNA
M3Y14_23695	COG1242	4 iron, 4 sulfur cluster binding
M3Y14_23700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M3Y14_23705	COG1794	racemase activity, acting on amino acids and derivatives
M3Y14_23720	COG2267	carboxylic ester hydrolase activity
M3Y14_23725	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M3Y14_23730	COG0671	phosphoesterase, PA-phosphatase related
M3Y14_23735	COG0438	transferase activity, transferring glycosyl groups
M3Y14_23760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
M3Y14_23765	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
M3Y14_23800	COG5002	protein histidine kinase activity
M3Y14_23805	COG3852	Histidine kinase
M3Y14_23810	COG0753	catalase activity
M3Y14_23815	COG2267	carboxylic ester hydrolase activity
M3Y14_23825	COG1368	sulfuric ester hydrolase activity
M3Y14_23835	COG4895	conserved protein (DUF2196)
M3Y14_23855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M3Y14_23860	COG1116	anion transmembrane transporter activity
M3Y14_23865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M3Y14_23885	COG0494	nUDIX hydrolase
M3Y14_23920	COG1854	S-ribosylhomocysteine lyase activity
M3Y14_23930	COG0288	reversible hydration of carbon dioxide
M3Y14_23935	COG1271	oxidase subunit
M3Y14_23940	COG1294	oxidase, subunit
M3Y14_23960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_23985	COG1842	Phage shock protein A
M3Y14_24010	COG3859	Proton-coupled thiamine transporter YuaJ
M3Y14_24015	COG5002	protein histidine kinase activity
M3Y14_24020	COG0745	RESPONSE REGULATOR receiver
M3Y14_24045	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M3Y14_24050	COG1597	lipid kinase activity
M3Y14_24065	COG1136	(ABC) transporter
M3Y14_24080	COG5002	protein histidine kinase activity
M3Y14_24090	COG0586	Pfam SNARE associated Golgi protein
M3Y14_24095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M3Y14_24110	COG0577	efflux transmembrane transporter activity
M3Y14_24115	COG1136	(ABC) transporter
M3Y14_24120	COG1959	2 iron, 2 sulfur cluster binding
M3Y14_24140	COG1131	(ABC) transporter
M3Y14_24145	COG5658	integral membrane protein
M3Y14_24150	COG5658	integral membrane protein
M3Y14_24155	COG0640	Transcriptional regulator
M3Y14_24165	COG1595	DNA-templated transcription, initiation
M3Y14_24170	COG0745	RESPONSE REGULATOR receiver
M3Y14_24175	COG2205	protein histidine kinase activity
M3Y14_24180	COG0577	efflux transmembrane transporter activity
M3Y14_24185	COG0577	efflux transmembrane transporter activity
M3Y14_24190	COG1136	(ABC) transporter
M3Y14_24195	COG0577	efflux transmembrane transporter activity
M3Y14_24210	COG2188	Transcriptional regulator
M3Y14_24230	COG3964	amidohydrolase
M3Y14_24245	COG0745	RESPONSE REGULATOR receiver
M3Y14_24250	COG4948	Mandelate Racemase Muconate Lactonizing
M3Y14_24260	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M3Y14_24265	COG0596	Alpha beta hydrolase
M3Y14_24270	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
M3Y14_24275	COG1169	isochorismate synthase
M3Y14_24280	COG1575	Belongs to the MenA family. Type 1 subfamily
M3Y14_24285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M3Y14_24290	COG1278	Cold shock
M3Y14_24315	COG0058	SHG alpha-glucan phosphorylase activity
M3Y14_24325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M3Y14_24330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M3Y14_24335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
M3Y14_24350	COG1309	transcriptional regulator
M3Y14_24435	COG1285	pathogenesis
M3Y14_24440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M3Y14_24450	COG0166	Belongs to the GPI family
M3Y14_24455	COG2155	Conserved Protein
M3Y14_24460	COG1098	S1 RNA binding domain
M3Y14_24465	COG0436	Aminotransferase
M3Y14_24470	COG1522	sequence-specific DNA binding
M3Y14_24475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M3Y14_24480	COG2267	carboxylic ester hydrolase activity
M3Y14_24490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M3Y14_24510	COG5018	Exonuclease
M3Y14_24515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M3Y14_24535	COG2050	protein possibly involved in aromatic compounds catabolism
M3Y14_24545	COG1268	BioY protein
M3Y14_24555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M3Y14_24560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M3Y14_24570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
M3Y14_24575	COG3584	3D domain protein
M3Y14_24595	COG1252	NADH dehydrogenase
M3Y14_24600	COG0492	ferredoxin-NADP+ reductase activity
M3Y14_24605	COG3708	Transcriptional regulator
M3Y14_24620	COG1683	Conserved Protein
M3Y14_24630	COG0316	Belongs to the HesB IscA family
M3Y14_24635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
M3Y14_24640	COG4844	belongs to the
M3Y14_24645	COG1252	NADH dehydrogenase
M3Y14_24660	COG0390	transport system, permease component
M3Y14_24665	COG2824	Alkylphosphonate utilization operon protein PhnA
M3Y14_24705	COG4837	Protein of unknown function (DUF1462)
M3Y14_24710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M3Y14_24720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M3Y14_24725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M3Y14_24745	COG1358	cellular component organization or biogenesis
M3Y14_24755	COG0647	UMP catabolic process
M3Y14_24765	COG2445	Protein of unknown function DUF86
M3Y14_24770	COG1494	fructose-1,6-bisphosphatase
M3Y14_24790	COG4470	Protein conserved in bacteria
M3Y14_24800	COG0789	Transcriptional regulator
M3Y14_24805	COG4377	Putative membrane peptidase family (DUF2324)
M3Y14_24830	COG0739	heme binding
M3Y14_24840	COG3377	Domain of unknown function (DUF1805)
M3Y14_24845	COG0737	Belongs to the 5'-nucleotidase family
M3Y14_24850	COG0719	Fe-S assembly protein
M3Y14_24855	COG0822	iron-sulfur transferase activity
M3Y14_24860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M3Y14_24865	COG0719	Fe-S assembly protein
M3Y14_24870	COG0396	ATPase activity
M3Y14_24875	COG1464	Belongs to the NlpA lipoprotein family
M3Y14_24880	COG1464	Belongs to the NlpA lipoprotein family
M3Y14_24885	COG2011	ABC-type metal ion transport system permease component
M3Y14_24900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M3Y14_24905	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M3Y14_24915	COG0509	glycine decarboxylation via glycine cleavage system
M3Y14_24920	COG1393	Belongs to the ArsC family
M3Y14_24965	COG1309	transcriptional regulator
M3Y14_24970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_24975	COG1960	acyl-CoA dehydrogenase activity
M3Y14_24980	COG0183	Belongs to the thiolase family
M3Y14_24985	COG1250	3-hydroxyacyl-CoA dehydrogenase
M3Y14_24985	COG1024	Enoyl-CoA hydratase
M3Y14_24995	COG1686	Belongs to the peptidase S11 family
M3Y14_25000	COG0506	proline dehydrogenase activity
M3Y14_25010	COG0011	TIGRFAM Protein of
M3Y14_25015	COG0840	transmembrane signaling receptor activity
M3Y14_25030	COG2814	Major facilitator Superfamily
M3Y14_25035	COG0531	amino acid
M3Y14_25055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3Y14_25065	COG5002	protein histidine kinase activity
M3Y14_25070	COG0745	RESPONSE REGULATOR receiver
M3Y14_25085	COG1131	(ABC) transporter
M3Y14_25110	COG0586	Pfam SNARE associated Golgi protein
M3Y14_25120	COG1376	ErfK ybiS ycfS ynhG family protein
M3Y14_25125	COG0745	RESPONSE REGULATOR receiver
M3Y14_25130	COG5002	protein histidine kinase activity
M3Y14_25145	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M3Y14_25160	COG0840	transmembrane signaling receptor activity
M3Y14_25165	COG2151	metal-sulfur cluster biosynthetic enzyme
M3Y14_25170	COG3227	Zinc metalloprotease (Elastase)
M3Y14_25190	COG0586	Pfam SNARE associated Golgi protein
M3Y14_25195	COG0475	glutathione-regulated potassium exporter activity
M3Y14_25200	COG0490	domain, Protein
M3Y14_25205	COG1115	amino acid carrier protein
M3Y14_25210	COG0783	Belongs to the Dps family
M3Y14_25225	COG1611	Belongs to the LOG family
M3Y14_25235	COG1528	Iron-storage protein
M3Y14_25245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3Y14_25250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3Y14_25255	COG1115	amino acid carrier protein
M3Y14_25260	COG1115	amino acid carrier protein
M3Y14_25265	COG2910	NAD(P)H-binding
M3Y14_25285	COG0656	L-ascorbic acid biosynthetic process
M3Y14_25290	COG2814	Major facilitator Superfamily
M3Y14_25295	COG1733	regulation of RNA biosynthetic process
M3Y14_25305	COG1252	NADH dehydrogenase
M3Y14_25310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M3Y14_25325	COG3290	protein histidine kinase activity
M3Y14_25325	COG0840	transmembrane signaling receptor activity
M3Y14_25365	COG0488	(ABC) transporter
M3Y14_25370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_25395	COG1522	sequence-specific DNA binding
M3Y14_25400	COG0288	reversible hydration of carbon dioxide
M3Y14_25405	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
M3Y14_25410	COG2233	PERMEase
M3Y14_25435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3Y14_25455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
M3Y14_25465	COG0557	exoribonuclease II activity
M3Y14_25470	COG1647	Serine aminopeptidase, S33
M3Y14_25475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M3Y14_25480	COG1346	cytolysis
M3Y14_25495	COG0148	phosphopyruvate hydratase activity
M3Y14_25510	COG0126	phosphoglycerate kinase activity
M3Y14_25515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M3Y14_25530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M3Y14_25560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M3Y14_25575	COG2323	membrane
M3Y14_25585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M3Y14_25590	COG1481	regulation of sporulation
M3Y14_25595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M3Y14_25600	COG1660	Displays ATPase and GTPase activities
M3Y14_25605	COG1051	belongs to the nudix hydrolase family
M3Y14_25615	COG0492	ferredoxin-NADP+ reductase activity
M3Y14_25620	COG0457	Tetratricopeptide repeat
M3Y14_25625	COG0110	maltose O-acetyltransferase activity
M3Y14_25630	COG0546	phosphoglycolate phosphatase activity
M3Y14_25635	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
M3Y14_25640	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
M3Y14_25645	COG1950	PFAM Membrane protein of
M3Y14_25650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M3Y14_25670	COG0789	Transcriptional regulator
M3Y14_25700	COG0583	DNA-binding transcription factor activity
M3Y14_25710	COG0655	NAD(P)H dehydrogenase (quinone) activity
M3Y14_25715	COG0488	(ABC) transporter
M3Y14_25725	COG1132	(ABC) transporter
M3Y14_25730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M3Y14_25735	COG0793	Belongs to the peptidase S41A family
M3Y14_25735	COG3409	Peptidoglycan-binding domain 1 protein
M3Y14_25740	COG2177	Part of the ABC transporter FtsEX involved in
M3Y14_25745	COG2884	Cell division ATP-binding protein ftsE
M3Y14_25775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M3Y14_25780	COG1278	Cold shock
M3Y14_25785	COG1040	competence protein
M3Y14_25790	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M3Y14_25795	COG0791	NLP P60 protein
M3Y14_25795	COG1388	LysM domain
M3Y14_25800	COG1733	regulation of RNA biosynthetic process
M3Y14_25805	COG1307	EDD domain protein, DegV family
M3Y14_25815	COG1739	Uncharacterized protein family UPF0029
M3Y14_25820	COG1316	TRANSCRIPTIONal
M3Y14_25825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M3Y14_25830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M3Y14_25835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M3Y14_25845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M3Y14_25845	COG3933	PFAM sigma-54 factor interaction domain-containing protein
M3Y14_25865	COG1486	melibiose metabolic process
M3Y14_25870	COG1447	Phosphotransferase system cellobiose-specific component IIA
M3Y14_25875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3Y14_25885	COG1447	Phosphotransferase system cellobiose-specific component IIA
M3Y14_25895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3Y14_25900	COG1301	dicarboxylic acid transport
M3Y14_25915	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M3Y14_25925	COG1271	oxidase subunit
M3Y14_25930	COG1294	oxidase, subunit
M3Y14_25935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M3Y14_25940	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
M3Y14_25945	COG1620	l-lactate permease
M3Y14_25955	COG2389	metal-binding protein
M3Y14_25965	COG1368	sulfuric ester hydrolase activity
M3Y14_25975	COG0791	NLP P60 protein
M3Y14_25975	COG1388	LysM domain
M3Y14_25980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3Y14_25990	COG1215	transferase activity, transferring glycosyl groups
M3Y14_25995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M3Y14_26000	COG3584	3D domain protein
M3Y14_26000	COG1388	LysM domain
M3Y14_26010	COG4715	Zinc finger, swim domain protein
M3Y14_26015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M3Y14_26055	COG0577	efflux transmembrane transporter activity
M3Y14_26060	COG1136	(ABC) transporter
M3Y14_26085	COG5002	protein histidine kinase activity
M3Y14_26085	COG3850	Histidine kinase
M3Y14_26090	COG0745	RESPONSE REGULATOR receiver
M3Y14_26095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M3Y14_26110	COG1482	cell wall glycoprotein biosynthetic process
M3Y14_26115	COG0662	Cupin 2, conserved barrel domain protein
M3Y14_26115	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
M3Y14_26130	COG0438	transferase activity, transferring glycosyl groups
M3Y14_26165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M3Y14_26170	COG4464	protein tyrosine phosphatase activity
M3Y14_26175	COG0489	protein tyrosine kinase activity
M3Y14_26180	COG3944	biosynthesis protein
M3Y14_26185	COG0489	protein tyrosine kinase activity
M3Y14_26200	COG1609	Transcriptional regulator
M3Y14_26210	COG0739	heme binding
M3Y14_26225	COG4555	ABC transporter
M3Y14_26230	COG2385	sporulation resulting in formation of a cellular spore
M3Y14_26245	COG4836	Membrane
M3Y14_26250	COG1007	ATP synthesis coupled electron transport
M3Y14_26255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M3Y14_26260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M3Y14_26265	COG0713	ATP synthesis coupled electron transport
M3Y14_26270	COG0839	Belongs to the complex I subunit 6 family
M3Y14_26280	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
M3Y14_26285	COG0649	NAD binding
M3Y14_26290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M3Y14_26300	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M3Y14_26305	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M3Y14_26310	COG5001	Diguanylate cyclase
M3Y14_26310	COG3300	MHYT domain
M3Y14_26325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
M3Y14_26330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
M3Y14_26335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
M3Y14_26340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
M3Y14_26345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M3Y14_26350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
M3Y14_26360	COG0356	it plays a direct role in the translocation of protons across the membrane
M3Y14_26385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
M3Y14_26395	COG0698	ribose 5-phosphate isomerase
M3Y14_26405	COG2190	(PTS) system
M3Y14_26410	COG2259	Doxx family
M3Y14_26415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M3Y14_26425	COG1971	Probably functions as a manganese efflux pump
M3Y14_26430	COG0009	L-threonylcarbamoyladenylate synthase
M3Y14_26445	COG2890	protein-(glutamine-N5) methyltransferase activity
M3Y14_26450	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
M3Y14_26455	COG1435	thymidine kinase activity
M3Y14_26465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M3Y14_26470	COG1494	fructose-1,6-bisphosphatase
M3Y14_26490	COG4821	SIS domain
M3Y14_26495	COG0504	CTP synthase activity
M3Y14_26510	COG1960	acyl-CoA dehydrogenase activity
M3Y14_26515	COG1960	acyl-CoA dehydrogenase activity
M3Y14_26520	COG1250	3-hydroxyacyl-CoA dehydrogenase
M3Y14_26525	COG0183	Belongs to the thiolase family
M3Y14_26530	COG2181	nitrate reductase activity
M3Y14_26530	COG0247	lactate metabolic process
M3Y14_26535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3Y14_26540	COG4294	response to UV
M3Y14_26545	COG3300	MHYT domain
M3Y14_26545	COG5001	Diguanylate cyclase
M3Y14_26560	COG3227	Zinc metalloprotease (Elastase)
M3Y14_26565	COG2197	response regulator
M3Y14_26570	COG4585	Histidine kinase
M3Y14_26575	COG0842	Transport permease protein
M3Y14_26580	COG1131	(ABC) transporter
M3Y14_26585	COG0024	Methionine aminopeptidase
M3Y14_26595	COG2234	aminopeptidase activity
M3Y14_26610	COG4506	Protein conserved in bacteria
M3Y14_26615	COG1619	proteins homologs of microcin C7 resistance protein MccF
M3Y14_26640	COG2814	Major facilitator Superfamily
M3Y14_26645	COG0789	Transcriptional regulator
M3Y14_26650	COG0584	glycerophosphoryl diester phosphodiesterase
M3Y14_26655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3Y14_26665	COG1994	Peptidase M50
M3Y14_26675	COG1078	dGTPase activity
M3Y14_26680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3Y14_26685	COG1120	ATPase activity
M3Y14_26690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_26695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3Y14_26700	COG4844	belongs to the
M3Y14_26715	COG0280	phosphate acetyltransferase
M3Y14_26720	COG3253	May function as heme-dependent peroxidase
M3Y14_26730	COG3773	Cell wall hydrolase
M3Y14_26740	COG2363	Small membrane protein
M3Y14_26750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M3Y14_26755	COG2233	PERMEase
M3Y14_26760	COG0561	phosphatase activity
M3Y14_26765	COG2814	Major facilitator Superfamily
M3Y14_26770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
M3Y14_26775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M3Y14_26780	COG1131	(ABC) transporter
M3Y14_26785	COG2755	lipolytic protein G-D-S-L family
M3Y14_26790	COG1609	Transcriptional regulator
M3Y14_26800	COG0460	homoserine dehydrogenase
M3Y14_26805	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
M3Y14_26810	COG2873	o-acetylhomoserine
M3Y14_26820	COG1011	Hydrolase
M3Y14_26825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M3Y14_26835	COG2197	response regulator
M3Y14_26840	COG4585	Histidine kinase
M3Y14_26840	COG2203	Gaf domain
M3Y14_26845	COG0351	phosphomethylpyrimidine kinase
M3Y14_26850	COG3706	GGDEF domain
M3Y14_26855	COG2879	small protein
M3Y14_26860	COG1966	Carbon starvation protein
M3Y14_26865	COG3279	Response regulator of the LytR AlgR family
M3Y14_26870	COG0477	Major facilitator Superfamily
M3Y14_26895	COG0840	transmembrane signaling receptor activity
M3Y14_26905	COG1607	acyl-coa hydrolase
M3Y14_26910	COG1216	Glycosyl transferase, family 2
M3Y14_26925	COG1216	Glycosyl transferase, family 2
M3Y14_26935	COG0488	(ABC) transporter
M3Y14_26950	COG0463	Glycosyl transferase, family 2
M3Y14_26955	COG1309	transcriptional regulator
M3Y14_26960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M3Y14_26965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M3Y14_26965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M3Y14_26970	COG0628	permease
M3Y14_26980	COG1380	Effector of murein hydrolase LrgA
M3Y14_26985	COG3279	Response regulator of the LytR AlgR family
M3Y14_26990	COG3275	phosphorelay sensor kinase activity
M3Y14_27000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M3Y14_27005	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M3Y14_27040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M3Y14_27045	COG1272	protein, Hemolysin III
M3Y14_27075	COG1164	Oligoendopeptidase f
M3Y14_27085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
M3Y14_27095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M3Y14_27100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M3Y14_27105	COG4853	Protein conserved in bacteria
M3Y14_27115	COG5002	protein histidine kinase activity
M3Y14_27120	COG0745	RESPONSE REGULATOR receiver
M3Y14_27150	COG0305	Participates in initiation and elongation during chromosome replication
M3Y14_27160	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M3Y14_27165	COG4241	membrane
M3Y14_27175	COG0629	single-stranded DNA binding
M3Y14_27180	COG0360	Binds together with S18 to 16S ribosomal RNA
M3Y14_27185	COG0012	GTP binding
M3Y14_27190	COG4481	Protein conserved in bacteria
M3Y14_27195	COG0668	transmembrane transport
M3Y14_27205	COG1475	DNA binding
M3Y14_27210	COG1192	Involved in chromosome partitioning
M3Y14_27215	COG1475	DNA binding
M3Y14_27220	COG0357	Ribosomal RNA small subunit methyltransferase G
M3Y14_27225	COG0445	tRNA wobble uridine modification
M3Y14_27230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
M3Y14_27235	COG1847	R3H domain protein
M3Y14_27240	COG0706	membrane insertase activity
M3Y14_27245	COG0594	ribonuclease P activity
M3Y14_27250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M3Y14_27255	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
M3Y14_27260	COG0592	DNA-directed DNA polymerase activity
M3Y14_27265	COG2501	S4 domain
M3Y14_27270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
M3Y14_27275	COG0187	DNA topoisomerase II activity
M3Y14_27280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M3Y14_27420	COG1522	sequence-specific DNA binding
M3Y14_27460	COG3011	Protein conserved in bacteria
M3Y14_27470	COG0772	Belongs to the SEDS family
M3Y14_27500	COG0582	viral genome integration into host DNA
M3Y14_27510	COG1266	CAAX protease self-immunity
M3Y14_27515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_27520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_27600	COG1396	sequence-specific DNA binding
M3Y14_27645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_27685	COG0737	Belongs to the 5'-nucleotidase family
M3Y14_27705	COG5632	N-Acetylmuramoyl-L-alanine amidase
M3Y14_27705	COG3409	Peptidoglycan-binding domain 1 protein
M3Y14_27765	COG0657	acetylesterase activity
M3Y14_27775	COG2814	Major facilitator Superfamily
M3Y14_27780	COG1309	transcriptional regulator
M3Y14_27795	COG0582	viral genome integration into host DNA
M3Y14_27895	COG0667	Aldo Keto reductase
M3Y14_27950	COG0740	serine-type endopeptidase activity
M3Y14_27960	COG4626	Terminase
M3Y14_27960	COG1802	Transcriptional regulator
M3Y14_28010	COG0582	viral genome integration into host DNA
M3Y14_28390	COG0582	viral genome integration into host DNA
M3Y14_28435	COG0582	viral genome integration into host DNA
M3Y14_28470	COG1388	LysM domain
M3Y14_28470	COG0791	NLP P60 protein
M3Y14_28690	COG4974	Belongs to the 'phage' integrase family
M3Y14_28750	COG5002	protein histidine kinase activity
M3Y14_28765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_28935	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M3Y14_29000	COG0582	viral genome integration into host DNA
M3Y14_29185	COG1316	TRANSCRIPTIONal
M3Y14_29190	COG0604	alcohol dehydrogenase
M3Y14_29195	COG1283	sodium-dependent phosphate transmembrane transporter activity
M3Y14_29200	COG2814	Major facilitator Superfamily
M3Y14_29210	COG3711	transcriptional antiterminator
M3Y14_29210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M3Y14_29215	COG1447	Phosphotransferase system cellobiose-specific component IIA
M3Y14_29220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3Y14_29240	COG1388	LysM domain
M3Y14_29240	COG3584	3D domain protein
M3Y14_29265	COG0745	RESPONSE REGULATOR receiver
M3Y14_29270	COG2205	protein histidine kinase activity
M3Y14_29285	COG1136	(ABC) transporter
M3Y14_29290	COG0577	efflux transmembrane transporter activity
M3Y14_29315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M3Y14_29345	COG1073	alpha beta
M3Y14_29375	COG0204	Acyl-transferase
M3Y14_29385	COG0582	viral genome integration into host DNA
M3Y14_29425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M3Y14_29455	COG4824	toxin secretion phage lysis holin
M3Y14_29465	COG1396	sequence-specific DNA binding
M3Y14_29490	COG2814	Major facilitator Superfamily
M3Y14_29620	COG0076	glutamate decarboxylase activity
M3Y14_29700	COG0582	viral genome integration into host DNA
M3Y14_29715	COG0741	lytic transglycosylase activity
M3Y14_29715	COG0739	heme binding
M3Y14_29715	COG1196	nuclear chromosome segregation
M3Y14_29725	COG1760	l-serine dehydratase
M3Y14_29730	COG1760	l-serine dehydratase
M3Y14_29735	COG1476	TRANSCRIPTIONal
M3Y14_29785	COG1842	Phage shock protein A
M3Y14_29815	COG1136	(ABC) transporter
M3Y14_29900	COG2814	Major facilitator Superfamily
M3Y14_30015	COG1674	ftsk spoiiie
M3Y14_30025	COG0741	lytic transglycosylase activity
M3Y14_30030	COG5002	protein histidine kinase activity
M3Y14_30035	COG0745	RESPONSE REGULATOR receiver
M3Y14_30045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M3Y14_30050	COG0563	adenylate kinase activity
M3Y14_30055	COG1388	LysM domain
M3Y14_30115	COG3681	Belongs to the UPF0597 family
M3Y14_30125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M3Y14_30180	COG2162	N-hydroxyarylamine O-acetyltransferase activity
M3Y14_30185	COG0789	Transcriptional regulator
M3Y14_30210	COG1011	Hydrolase
M3Y14_30290	COG1876	peptidase activity
M3Y14_30435	COG0577	efflux transmembrane transporter activity
M3Y14_30440	COG1136	(ABC) transporter
M3Y14_30455	COG0745	RESPONSE REGULATOR receiver
M3Y14_30480	COG4152	abc transporter atp-binding protein
M3Y14_30495	COG0706	membrane insertase activity
M3Y14_30545	COG2357	RelA SpoT domain protein
M3Y14_30550	COG2814	Major facilitator Superfamily
M3Y14_30575	COG0745	RESPONSE REGULATOR receiver
M3Y14_30745	COG0457	Tetratricopeptide repeat
M3Y14_30920	COG0741	lytic transglycosylase activity
M3Y14_30920	COG0791	NLP P60 protein
M3Y14_31020	COG2801	Transposase and inactivated derivatives
M3Y14_31070	COG0823	Involved in the tonB-independent uptake of proteins
M3Y14_31110	COG4974	Belongs to the 'phage' integrase family
M3Y14_31125	COG4166	transmembrane transport
M3Y14_31145	COG0745	RESPONSE REGULATOR receiver
M3Y14_31200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M3Y14_31205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M3Y14_31210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M3Y14_31215	COG0438	transferase activity, transferring glycosyl groups
M3Y14_31235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M3Y14_31240	COG0438	transferase activity, transferring glycosyl groups
M3Y14_31245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M3Y14_31275	COG0825	malonyl-CoA metabolic process
M3Y14_31315	COG4644	lycopene metabolic process
M3Y14_31340	COG1404	Belongs to the peptidase S8 family
M3Y14_31350	COG3711	transcriptional antiterminator
M3Y14_31355	COG3711	transcriptional antiterminator
M3Y14_31360	COG0823	Involved in the tonB-independent uptake of proteins
M3Y14_31370	COG1115	amino acid carrier protein
M3Y14_31375	COG1114	Component of the transport system for branched-chain amino acids
M3Y14_31380	COG1115	amino acid carrier protein
M3Y14_31430	COG3773	Cell wall hydrolase
M3Y14_31440	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_31505	COG4974	Belongs to the 'phage' integrase family
M3Y14_31525	COG1136	(ABC) transporter
M3Y14_31610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M3Y14_31630	COG2311	Membrane
M3Y14_31640	COG1720	tRNA m6t6A37 methyltransferase activity
M3Y14_31645	COG2318	DinB family
M3Y14_31655	COG0640	Transcriptional regulator
M3Y14_31665	COG1923	regulation of RNA biosynthetic process
M3Y14_31670	COG2002	toxin-antitoxin pair type II binding
M3Y14_31680	COG0697	spore germination
M3Y14_31685	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M3Y14_31690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M3Y14_31695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M3Y14_31705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3Y14_31740	COG4974	Belongs to the 'phage' integrase family
M3Y14_31870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M3Y14_31875	COG1522	sequence-specific DNA binding
M3Y14_31880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M3Y14_31885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3Y14_31945	COG1396	sequence-specific DNA binding
M3Y14_32155	COG1192	Involved in chromosome partitioning
M3Y14_32195	COG4166	transmembrane transport
M3Y14_32215	COG0457	Tetratricopeptide repeat
M3Y14_32225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M3Y14_32280	COG4974	Belongs to the 'phage' integrase family
M3Y14_32365	COG0551	DNA topoisomerase type I activity
M3Y14_32365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M3Y14_32460	COG0791	NLP P60 protein
M3Y14_32460	COG0741	lytic transglycosylase activity
M3Y14_32665	COG0457	Tetratricopeptide repeat
M3Y14_32840	COG0791	NLP P60 protein
M3Y14_32840	COG0741	lytic transglycosylase activity
M3Y14_33065	COG1609	Transcriptional regulator
M3Y14_33070	COG2814	Major facilitator Superfamily
M3Y14_33075	COG0673	inositol 2-dehydrogenase activity
M3Y14_33105	COG3718	enzyme involved in inositol metabolism
M3Y14_33130	COG0697	spore germination
M3Y14_33135	COG1252	NADH dehydrogenase
M3Y14_33140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_33140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3Y14_33185	COG0833	amino acid
M3Y14_33190	COG2040	homocysteine
M3Y14_33205	COG1309	transcriptional regulator
M3Y14_33215	COG1250	3-hydroxyacyl-CoA dehydrogenase
M3Y14_33225	COG0577	efflux transmembrane transporter activity
M3Y14_33235	COG1028	Short-chain dehydrogenase reductase Sdr
M3Y14_33300	COG4974	Belongs to the 'phage' integrase family
M3Y14_33315	COG0577	efflux transmembrane transporter activity
M3Y14_33320	COG1136	(ABC) transporter
M3Y14_33355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M3Y14_33375	COG2186	Transcriptional regulator
M3Y14_33455	COG1733	regulation of RNA biosynthetic process
M3Y14_33460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M3Y14_33510	COG2002	toxin-antitoxin pair type II binding
M3Y14_33515	COG1923	regulation of RNA biosynthetic process
M3Y14_33520	COG1192	Involved in chromosome partitioning
M3Y14_33580	COG0457	Tetratricopeptide repeat
M3Y14_33580	COG0463	Glycosyl transferase, family 2
M3Y14_33705	COG0741	lytic transglycosylase activity
M3Y14_33705	COG0791	NLP P60 protein
M3Y14_34015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M3Y14_34130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M3Y14_34180	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M3Y14_34245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M3Y14_34305	COG0210	DNA helicase
M3Y14_34315	COG0358	DNA primase activity
M3Y14_34365	COG0592	DNA-directed DNA polymerase activity
M3Y14_34475	COG0457	Tetratricopeptide repeat
M3Y14_34520	COG0194	GDP metabolic process
M3Y14_34600	COG1404	Belongs to the peptidase S8 family
M3Y14_34610	COG0590	tRNA wobble adenosine to inosine editing
M3Y14_34640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M3Y14_34645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M3Y14_34705	COG0305	Participates in initiation and elongation during chromosome replication
M3Y14_34780	COG2133	pyrroloquinoline quinone binding
M3Y14_34780	COG5183	chlorophyll binding
M3Y14_34835	COG2197	response regulator
M3Y14_34840	COG4585	Histidine kinase