locus-tag class description BtSCAC15_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BtSCAC15_00015 ENOG410848D S4 domain protein YaaA BtSCAC15_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BtSCAC15_00065 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BtSCAC15_00100 ENOG4105ZMH deoxynucleoside kinase BtSCAC15_00110 ENOG4105GTG Isochorismatase BtSCAC15_00120 ENOG4108Z6B deaminase BtSCAC15_00130 ENOG4105C6E dna polymerase iii BtSCAC15_00150 ENOG41067KS pro-sigma K processing BtSCAC15_00180 ENOG4105CXN decarboxylase BtSCAC15_00190 ENOG4105FA2 dna polymerase iii BtSCAC15_00195 ENOG4105MA4 psp1 domain protein BtSCAC15_00205 ENOG41060K3 Methyltransferase BtSCAC15_00215 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BtSCAC15_00220 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_00225 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BtSCAC15_00230 ENOG4105F8V Hydrolase, tatD family BtSCAC15_00235 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BtSCAC15_00245 ENOG4105XFA sporulation peptidase YabG BtSCAC15_00250 ENOG4105W42 Veg protein BtSCAC15_00265 ENOG4105DFT pur operon repressor BtSCAC15_00270 ENOG4105KME endoribonuclease L-psp BtSCAC15_00285 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BtSCAC15_00290 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BtSCAC15_00300 ENOG4108JA2 transcriptioN-repair coupling factor BtSCAC15_00305 ENOG4108M14 stage v sporulation protein t BtSCAC15_00315 ENOG4108IY2 MazG family BtSCAC15_00320 ENOG41082I2 s4 domain protein BtSCAC15_00325 ENOG4105VYY sporulation protein yabp BtSCAC15_00340 ENOG41060GV RNA binding s1 domain protein BtSCAC15_00360 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BtSCAC15_00365 ENOG4108UGV hypoxanthine phosphoribosyltransferase BtSCAC15_00370 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BtSCAC15_00385 ENOG4105C6T cysteine synthase BtSCAC15_00400 ENOG4105DQ6 Transposase BtSCAC15_00415 ENOG4105CRQ synthase (Component I) BtSCAC15_00420 ENOG4105DDQ anthranilate synthase BtSCAC15_00425 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BtSCAC15_00430 ENOG4105EEI dihydropteroate synthase BtSCAC15_00435 ENOG4105KRF dihydroneopterin aldolase BtSCAC15_00440 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BtSCAC15_00450 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BtSCAC15_00490 ENOG4108Z0C Uvrb UvrC protein BtSCAC15_00505 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BtSCAC15_00510 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) BtSCAC15_00515 ENOG4105CTP PilT protein domain protein BtSCAC15_00520 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BtSCAC15_00535 ENOG4105D7W serine acetyltransferase BtSCAC15_00550 ENOG4105C2N RNA methyltransferase TrmH family group 3 BtSCAC15_00555 ENOG4105M0M Tetracycline resistance protein BtSCAC15_00560 ENOG4105QIV RNA polymerase BtSCAC15_00575 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BtSCAC15_00600 ENOG4107Y49 methyltransferase BtSCAC15_00615 ENOG4105XPM ribosomal protein BtSCAC15_00725 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BtSCAC15_00750 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BtSCAC15_00760 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BtSCAC15_00770 ENOG41067V7 50S ribosomal protein L36 BtSCAC15_00795 ENOG4108JJB ABC transporter BtSCAC15_00800 ENOG4108JJB ABC transporter BtSCAC15_00805 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BtSCAC15_00810 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BtSCAC15_00835 ENOG4105D1F ATP-binding protein BtSCAC15_00850 ENOG4108NMV polysaccharide deacetylase BtSCAC15_00935 ENOG4105C8B TIGR00159 family BtSCAC15_00940 ENOG4107U5W ybbr family BtSCAC15_00955 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BtSCAC15_01085 ENOG4108C33 Resolvase BtSCAC15_01090 ENOG4105DQ6 Transposase BtSCAC15_01100 ENOG4108UMI ABC transporter, permease BtSCAC15_01105 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BtSCAC15_01110 ENOG4105D01 (LipO)protein BtSCAC15_01115 ENOG4105EE1 crotonyl-CoA reductase BtSCAC15_01125 ENOG4105IQ5 FAD linked oxidase domain protein BtSCAC15_01140 ENOG4105C2C drug resistance transporter, Bcr CflA BtSCAC15_01165 ENOG4105DQ6 Transposase BtSCAC15_01190 ENOG4108J59 Extracellular solute-binding protein, family 5 BtSCAC15_01225 ENOG4105E0C molybdate abc transporter BtSCAC15_01230 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BtSCAC15_01235 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BtSCAC15_01255 ENOG4105EGI Transcriptional regulator BtSCAC15_01280 ENOG4105F6E Acyl-transferase BtSCAC15_01305 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BtSCAC15_01330 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BtSCAC15_01355 ENOG4105C5H ABC transporter BtSCAC15_01370 ENOG4105DEF Extracellular solute-binding protein, family 5 BtSCAC15_01380 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BtSCAC15_01385 ENOG4105C3U ABC transporter BtSCAC15_01390 ENOG4108JQ7 (ABC) transporter BtSCAC15_01395 ENOG410667J hydrolase BtSCAC15_01420 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BtSCAC15_01425 ENOG4105ERH Fumarylacetoacetate hydrolase BtSCAC15_01440 ENOG4105CUB amino acid BtSCAC15_01445 ENOG4108SC4 )-transporter BtSCAC15_01450 ENOG4105CPF Cell wall formation (By similarity) BtSCAC15_01455 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BtSCAC15_01480 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BtSCAC15_01485 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BtSCAC15_01495 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BtSCAC15_01595 ENOG4105K8N protein family UPF0079, ATPase BtSCAC15_01600 ENOG41072GX Peptidase M22 Glycoprotease BtSCAC15_01605 ENOG410801F ribosomal-protein-alanine acetyltransferase BtSCAC15_01610 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BtSCAC15_01615 ENOG4105C5H ABC transporter BtSCAC15_01630 ENOG4108TYN CAAX amino terminal protease family protein BtSCAC15_01640 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BtSCAC15_01645 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BtSCAC15_01650 ENOG4105C7N Xanthine uracil vitamin C permease BtSCAC15_01660 ENOG4105BZU Histidine kinase BtSCAC15_01690 ENOG4107ZXU DSBA oxidoreductase BtSCAC15_01720 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BtSCAC15_01730 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) BtSCAC15_01740 ENOG4108SHN Glycosyl transferase, family 2 BtSCAC15_01760 ENOG4105SX7 Transporter BtSCAC15_01790 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BtSCAC15_01795 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BtSCAC15_01800 ENOG4105C83 adenylosuccinate lyase BtSCAC15_01810 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BtSCAC15_01835 ENOG4108V3E phosphoribosylglycinamide formyltransferase BtSCAC15_01840 ENOG4105DC1 bifunctional purine biosynthesis protein purh BtSCAC15_01845 ENOG4105C12 Phosphoribosylglycinamide synthetase BtSCAC15_01875 ENOG4105C4R Atp-dependent dna helicase BtSCAC15_01880 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BtSCAC15_01900 ENOG4108W2Y isochorismatase BtSCAC15_01905 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BtSCAC15_01910 ENOG4108UMI ABC transporter, permease BtSCAC15_01915 ENOG4105D01 (LipO)protein BtSCAC15_01935 ENOG410834F Transcriptional regulator BtSCAC15_01940 ENOG4107I77 yiaA/B two helix domain BtSCAC15_01950 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BtSCAC15_01960 ENOG4105CBD Diacylglycerol kinase BtSCAC15_01970 ENOG4108JPW Aminotransferase BtSCAC15_01980 ENOG4105C26 Dehydrogenase BtSCAC15_01985 ENOG4105KPY Small multidrug resistance protein BtSCAC15_02020 ENOG4105D9N nucleoside BtSCAC15_02025 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BtSCAC15_02045 ENOG4108W15 Protein of unknown function (DUF1456) BtSCAC15_02060 ENOG4105DTQ mandelate racemase muconate lactonizing BtSCAC15_02070 ENOG4105DFD Na H antiporter BtSCAC15_02090 ENOG4105D3R alkyl hydroperoxide reductase BtSCAC15_02095 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BtSCAC15_02100 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BtSCAC15_02105 ENOG4107W7X Aldolase BtSCAC15_02110 ENOG4105EHG Permease protein BtSCAC15_02115 ENOG4105DQ5 transport system permease protein BtSCAC15_02120 ENOG4108V5C ABC transporter BtSCAC15_02130 ENOG4105CAY ferredoxin--nadp reductase BtSCAC15_02150 ENOG4106UIA BtSCAC15_02155 ENOG4106UIA BtSCAC15_02170 ENOG4105BZU Histidine kinase BtSCAC15_02190 ENOG410756H nucleotidyltransferase BtSCAC15_02195 ENOG4105D2S major facilitator superfamily BtSCAC15_02210 ENOG4105E5Q amino acid AbC transporter BtSCAC15_02215 ENOG4105EAB amino acid AbC transporter BtSCAC15_02220 ENOG4105CDA abc transporter atp-binding protein BtSCAC15_02225 ENOG4105C8Q Methyl-accepting chemotaxis BtSCAC15_02250 ENOG4105DBV ornithine carbamoyltransferase BtSCAC15_02260 ENOG4105C5B carbamate kinase BtSCAC15_02265 ENOG4108W63 CRP FNR family transcriptional regulator BtSCAC15_02275 ENOG4105DNP FAD linked oxidase domain protein BtSCAC15_02285 ENOG4105CI1 PTS System BtSCAC15_02300 ENOG4105C9U ATP-dependent DNA helicase RecQ BtSCAC15_02305 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BtSCAC15_02315 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BtSCAC15_02335 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BtSCAC15_02340 ENOG4105D2X ABC transporter substrate-binding protein BtSCAC15_02350 ENOG4105C5H ABC transporter BtSCAC15_02385 ENOG41062JF Transcriptional regulator BtSCAC15_02410 ENOG4105DEU major facilitator superfamily BtSCAC15_02425 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BtSCAC15_02440 ENOG4108N0M stress protein BtSCAC15_02445 ENOG4106FN3 tellurium resistance protein BtSCAC15_02450 ENOG4106FN3 tellurium resistance protein BtSCAC15_02455 ENOG4107TS3 membrane protein, TerC BtSCAC15_02460 ENOG4108TTB tellurium resistance protein BtSCAC15_02475 ENOG41068PA UPF0435 protein BtSCAC15_02480 ENOG4105KJF protein tyrosine phosphatase BtSCAC15_02490 ENOG4107U9T Pfam:Ribonuclease_BN BtSCAC15_02500 ENOG4105C59 p-type ATPase BtSCAC15_02505 ENOG4108IPJ Membrane BtSCAC15_02515 ENOG4105C3F Signal peptidase i BtSCAC15_02525 ENOG4107ZTW SNARE associated Golgi BtSCAC15_02550 ENOG410606W general stress protein BtSCAC15_02555 ENOG4105UPD Calcium Proton BtSCAC15_02590 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BtSCAC15_02600 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BtSCAC15_02610 ENOG4108JUB Transcriptional regulator BtSCAC15_02620 ENOG4108IQI permease BtSCAC15_02670 ENOG4108A04 Beta-lactamase BtSCAC15_02685 ENOG4105CKK Glycosyl transferase, family 2 BtSCAC15_02690 ENOG4107QQG Dehydrogenase BtSCAC15_02695 ENOG4105C3I Nad-dependent epimerase dehydratase BtSCAC15_02715 ENOG4105F1A Pyruvate formate-lyase BtSCAC15_02720 ENOG4108QBV Monogalactosyldiacylglycerol synthase BtSCAC15_02735 ENOG4105CI2 imidazolone-5-propionate hydrolase BtSCAC15_02740 ENOG4105ECP epimerase BtSCAC15_02780 ENOG41067AE Membrane-bound metal-dependent hydrolase BtSCAC15_02785 ENOG4105CEN a g-specific adenine glycosylase BtSCAC15_02790 ENOG4106BXE BtSCAC15_02810 ENOG4105BZ1 (ABC) transporter BtSCAC15_02815 ENOG4107NBY Membrane BtSCAC15_02820 ENOG4105CBC glutamate synthase BtSCAC15_02830 ENOG4108IUW ABC transporter BtSCAC15_02850 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BtSCAC15_02855 ENOG4105G5W regulator Fur family BtSCAC15_02960 ENOG4105CDY transcriptional regulatory protein BtSCAC15_02970 ENOG4108JQC penicillin-binding protein 1A BtSCAC15_02975 ENOG4108R9S DSBA oxidoreductase BtSCAC15_02985 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BtSCAC15_02995 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BtSCAC15_03000 ENOG4105BZU Histidine kinase BtSCAC15_03010 ENOG4105CYN Serine protein kinase BtSCAC15_03020 ENOG4106AKX UPF0229 protein BtSCAC15_03045 ENOG4108MK9 spermidine N(1)-acetyltransferase BtSCAC15_03050 ENOG4105C94 Transporter BtSCAC15_03065 ENOG4105DZ6 Band 7 protein BtSCAC15_03075 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BtSCAC15_03100 ENOG4105D4T Citrate transporter BtSCAC15_03120 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BtSCAC15_03125 ENOG4108IJ9 (ABC) transporter BtSCAC15_03135 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BtSCAC15_03150 ENOG4105DQ6 Transposase BtSCAC15_03175 ENOG4108MRH transcriptional regulatory protein BtSCAC15_03185 ENOG4105C6K Malic enzyme BtSCAC15_03195 ENOG4108UZ3 Transporter BtSCAC15_03205 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BtSCAC15_03215 ENOG4105BZU Histidine kinase BtSCAC15_03235 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BtSCAC15_03240 ENOG4108JB9 formate dehydrogenase BtSCAC15_03265 ENOG4105CUB amino acid BtSCAC15_03275 ENOG4105C59 p-type ATPase BtSCAC15_03280 ENOG4105DAP Nicotinate phosphoribosyltransferase BtSCAC15_03315 ENOG41073R8 VanW family BtSCAC15_03320 ENOG4108KGH TRANSCRIPTIONal BtSCAC15_03325 ENOG4105D9N nucleoside BtSCAC15_03330 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BtSCAC15_03335 ENOG4105C37 (CBS) domain BtSCAC15_03340 ENOG4108IJ0 Aspartate ammonia-lyase BtSCAC15_03345 ENOG4105DAA L-lactate BtSCAC15_03360 ENOG4105DUX Transporter BtSCAC15_03365 ENOG4108MES Periplasmic binding protein BtSCAC15_03370 ENOG4105DQ5 transport system permease protein BtSCAC15_03375 ENOG4108IHU transport system permease protein BtSCAC15_03380 ENOG4105E0A ABC, transporter BtSCAC15_03390 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BtSCAC15_03395 ENOG4105EXW epimerase dehydratase BtSCAC15_03405 ENOG4107T89 von Willebrand factor, type A BtSCAC15_03410 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BtSCAC15_03415 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BtSCAC15_03430 ENOG4105BZU Histidine kinase BtSCAC15_03435 ENOG4105D5Q Arginine ornithine antiporter BtSCAC15_03440 ENOG4107414 GntR family transcriptional regulator BtSCAC15_03445 ENOG4105C5Y PTS System BtSCAC15_03450 ENOG4105CG3 alpha amylase, catalytic region BtSCAC15_03465 ENOG4105E1K spore germination protein BtSCAC15_03475 ENOG4105CRN Aminoglycoside phosphotransferase BtSCAC15_03480 ENOG4105BZG amino acid carrier protein BtSCAC15_03490 ENOG4105CDA abc transporter atp-binding protein BtSCAC15_03495 ENOG4105CT1 (ABC) transporter BtSCAC15_03500 ENOG4105EAD ABC transporter BtSCAC15_03505 ENOG4105DRP amino acid AbC transporter BtSCAC15_03510 ENOG4108IQI permease BtSCAC15_03535 ENOG4105D29 Helix-turn-helix type 11 domain protein BtSCAC15_03540 ENOG4105NAE bifunctional deaminase-reductase domain protein BtSCAC15_03545 ENOG4105BZU Histidine kinase BtSCAC15_03560 ENOG4105CHH sulfate transporter BtSCAC15_03565 ENOG41068KF Universal stress protein BtSCAC15_03575 ENOG4105CXY transporter BtSCAC15_03580 ENOG41067TZ transcriptional regulator, MarR family BtSCAC15_03585 ENOG4105C0R drug resistance transporter emrb qaca subfamily BtSCAC15_03590 ENOG4105ETE Transcriptional regulator (LacI family BtSCAC15_03595 ENOG4108RVA ribokinase BtSCAC15_03605 ENOG4105C2J ABC transporter BtSCAC15_03610 ENOG4105CNN ABC, transporter BtSCAC15_03615 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BtSCAC15_03620 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BtSCAC15_03670 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) BtSCAC15_03690 ENOG4108IMY Transcriptional regulator BtSCAC15_03740 ENOG4105C7K acetolactate synthase BtSCAC15_03815 ENOG4108N9J Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BtSCAC15_03885 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BtSCAC15_03910 ENOG4105DNP FAD linked oxidase domain protein BtSCAC15_03940 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BtSCAC15_03955 ENOG4105CNU cell division protein FtsK BtSCAC15_03995 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BtSCAC15_04000 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BtSCAC15_04005 ENOG41069ER domain protein BtSCAC15_04025 ENOG4107D63 BtSCAC15_04065 ENOG4105C85 amino acid BtSCAC15_04070 ENOG4105C7N Xanthine uracil vitamin C permease BtSCAC15_04085 ENOG4105MA6 gCN5-related N-acetyltransferase BtSCAC15_04110 ENOG4105BZ9 Cytochrome C oxidase, subunit I BtSCAC15_04115 ENOG4105E2S oxidase) subunit II BtSCAC15_04140 ENOG4106CAD Protein of unknown function (DUF3311) BtSCAC15_04145 ENOG4105E1V na solute symporter BtSCAC15_04160 ENOG4108NHD germination protein BtSCAC15_04170 ENOG4105CE1 Ferrous iron transport protein b BtSCAC15_04175 ENOG4105CE1 Ferrous iron transport protein b BtSCAC15_04180 ENOG4105CE1 Ferrous iron transport protein b BtSCAC15_04185 ENOG4105CVA phosphate BtSCAC15_04190 ENOG4105C8U phosphate abc transporter BtSCAC15_04195 ENOG4105E2Z phosphate ABC transporter (Permease BtSCAC15_04320 ENOG41080XQ Signal transduction protein with cbs domains BtSCAC15_04345 ENOG4105ETU transcriptional activator (TenA BtSCAC15_04355 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BtSCAC15_04365 ENOG4108VEU Thiamine monophosphate synthase BtSCAC15_04370 ENOG41080HI glycine oxidase BtSCAC15_04385 ENOG4105D06 uba thif-type nad fad binding protein BtSCAC15_04390 ENOG4105DWF phosphomethylpyrimidine kinase BtSCAC15_04430 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) BtSCAC15_04445 ENOG4108INS Transcriptional regulator BtSCAC15_04455 ENOG4105C7N Xanthine uracil vitamin C permease BtSCAC15_04465 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BtSCAC15_04485 ENOG4105C5Y PTS System BtSCAC15_04500 ENOG4105K63 Thioredoxin BtSCAC15_04520 ENOG4108B31 Spore germination protein BtSCAC15_04540 ENOG4107Y03 Nitroreductase BtSCAC15_04545 ENOG4105ED1 spovr family BtSCAC15_04555 ENOG4105J4Q Transcriptional regulator BtSCAC15_04570 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BtSCAC15_04575 ENOG4105XTG Pfam:DUF156 BtSCAC15_04580 ENOG4105VFE sira family BtSCAC15_04585 ENOG4107TPS domain protein BtSCAC15_04590 ENOG4105VFE sira family BtSCAC15_04595 ENOG4105VFE sira family BtSCAC15_04600 ENOG41085GJ domain protein BtSCAC15_04605 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BtSCAC15_04610 ENOG41087NI Sulfite exporter TauE/SafE BtSCAC15_04620 ENOG4108KGH TRANSCRIPTIONal BtSCAC15_04660 ENOG4105EMD TRANSCRIPTIONal BtSCAC15_04665 ENOG4105VCP PTS System BtSCAC15_04670 ENOG4105VZJ PTS System BtSCAC15_04690 ENOG41069ER domain protein BtSCAC15_04695 ENOG4107RBB ABC transporter, permease BtSCAC15_04700 ENOG4105C19 ABC transporter BtSCAC15_04730 ENOG4105WEF catalase BtSCAC15_04765 ENOG4107T5V SNARE associated Golgi BtSCAC15_04800 ENOG4105CUB amino acid BtSCAC15_04805 ENOG4107RWR Sodium hydrogen exchanger BtSCAC15_04815 ENOG4106KNT transcriptional regulator BtSCAC15_04820 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BtSCAC15_04855 ENOG4108YXU transcriptional regulator AsnC family BtSCAC15_04860 ENOG4105CH7 arginosuccinase BtSCAC15_04865 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BtSCAC15_04875 ENOG4105KPY Small multidrug resistance protein BtSCAC15_04940 ENOG4107RKG DJ-1/PfpI family BtSCAC15_04950 ENOG4105CH6 catalase BtSCAC15_04960 ENOG4105D5Q Arginine ornithine antiporter BtSCAC15_04965 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BtSCAC15_04975 ENOG4105C26 Dehydrogenase BtSCAC15_04995 ENOG4105BZ1 (ABC) transporter BtSCAC15_05000 ENOG4105BZ1 (ABC) transporter BtSCAC15_05015 ENOG4105DRP amino acid AbC transporter BtSCAC15_05020 ENOG4105CDA abc transporter atp-binding protein BtSCAC15_05035 ENOG410839P BtSCAC15_05045 ENOG4108UH6 UPF0754 membrane protein BtSCAC15_05070 ENOG4107FQX Alpha-acetolactate decarboxylase BtSCAC15_05075 ENOG4108VX5 3-methyladenine DNA glycosylase BtSCAC15_05090 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BtSCAC15_05095 ENOG4105D4P Coproporphyrinogen iii oxidase BtSCAC15_05105 ENOG4105CEY Amp-dependent synthetase and ligase BtSCAC15_05120 ENOG4105CHH sulfate transporter BtSCAC15_05145 ENOG4105CGU Enoyl-CoA hydratase BtSCAC15_05205 ENOG4105CIF Ornithine Cyclodeaminase BtSCAC15_05240 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BtSCAC15_05250 ENOG4108JQ7 (ABC) transporter BtSCAC15_05305 ENOG4108IBT Inherit from COG: transposase BtSCAC15_05360 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BtSCAC15_05365 ENOG4105K70 DNA-binding protein BtSCAC15_05400 ENOG4105CSH Transporter BtSCAC15_05410 ENOG4108MRH transcriptional regulatory protein BtSCAC15_05475 ENOG4105CDU Replicative dna helicase BtSCAC15_05505 ENOG4105C0R drug resistance transporter emrb qaca subfamily BtSCAC15_05520 ENOG4105D9U N-acetyltransferase BtSCAC15_05545 ENOG4105F6J Alpha beta hydrolase fold BtSCAC15_05600 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BtSCAC15_05615 ENOG4105CMT Dihydroxyacetone kinase BtSCAC15_05625 ENOG4105CMT Dihydroxyacetone kinase BtSCAC15_05745 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BtSCAC15_05760 ENOG4105DQ6 Transposase BtSCAC15_05770 ENOG4108MJI response regulator BtSCAC15_05775 ENOG4105BZU Histidine kinase BtSCAC15_05780 ENOG4105BZU Histidine kinase BtSCAC15_05805 ENOG4105K8R UPF0145 protein BtSCAC15_05825 ENOG4107QHE Choloylglycine hydrolase BtSCAC15_05845 ENOG4107VRP DNA repair exonuclease BtSCAC15_05850 ENOG4106D4I domain protein BtSCAC15_05865 ENOG410829K Lysine exporter protein (Lyse ygga) BtSCAC15_05890 ENOG4108MUZ hydrolase BtSCAC15_05910 ENOG4105F0F Oxalate decarboxylase BtSCAC15_05915 ENOG41067QW Transcriptional regulator BtSCAC15_05920 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BtSCAC15_05935 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BtSCAC15_05960 ENOG4105EEM helicase BtSCAC15_05970 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BtSCAC15_06000 ENOG4105K59 histidine triad (HIT) protein BtSCAC15_06040 ENOG410905X membrane-flanked domain protein BtSCAC15_06045 ENOG4105CKV Membrane BtSCAC15_06070 ENOG4105EKQ RNA-directed DNA polymerase BtSCAC15_06095 ENOG4105DQ6 Transposase BtSCAC15_06120 ENOG410905X membrane-flanked domain protein BtSCAC15_06125 ENOG4105CKV Membrane BtSCAC15_06135 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BtSCAC15_06140 ENOG4105BZ4 penicillin-binding protein BtSCAC15_06150 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BtSCAC15_06155 ENOG4105C1Q protoporphyrinogen oxidase BtSCAC15_06180 ENOG4105NA0 Transcriptional regulator BtSCAC15_06195 ENOG4105ECB domain protein BtSCAC15_06210 ENOG4108MK9 spermidine N(1)-acetyltransferase BtSCAC15_06220 ENOG4106AXD BtSCAC15_06225 ENOG4108RQ5 Beta-lactamase domain-containing protein BtSCAC15_06230 ENOG4105DF9 Lipoate-protein, ligase BtSCAC15_06240 ENOG4105CEY Amp-dependent synthetase and ligase BtSCAC15_06250 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BtSCAC15_06255 ENOG4108I5D sulfate abc transporter BtSCAC15_06270 ENOG4108IJ6 ABC transporter BtSCAC15_06275 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BtSCAC15_06285 ENOG4107RN3 metallophosphoesterase BtSCAC15_06290 ENOG4107TVP HD domain protein BtSCAC15_06295 ENOG4108AEY RNA polymerase sigma factor BtSCAC15_06300 ENOG41086D8 Transcriptional regulator BtSCAC15_06315 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BtSCAC15_06335 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BtSCAC15_06340 ENOG4105C8Q Methyl-accepting chemotaxis BtSCAC15_06345 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) BtSCAC15_06355 ENOG4107QP3 malate synthase g BtSCAC15_06385 ENOG4105VEQ Cold shock protein BtSCAC15_06430 ENOG4108FPN Integrase BtSCAC15_06440 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BtSCAC15_06485 ENOG4105ERH Fumarylacetoacetate hydrolase BtSCAC15_06495 ENOG4105C8Y Acetylornithine aminotransferase BtSCAC15_06500 ENOG4106BKT UPF0344 protein BtSCAC15_06510 ENOG4105CAQ asparagine synthetase BtSCAC15_06525 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BtSCAC15_06600 ENOG4105CAQ asparagine synthetase BtSCAC15_06605 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BtSCAC15_06610 ENOG4105CH6 catalase BtSCAC15_06615 ENOG4105BZU Histidine kinase BtSCAC15_06635 ENOG4108VPT UPF0234 protein BtSCAC15_06640 ENOG4105QNR S1 RNA binding domain protein BtSCAC15_06645 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BtSCAC15_06655 ENOG4107AYK membrAne BtSCAC15_06660 ENOG41073B9 BtSCAC15_06670 ENOG4108KP7 hydrolase BtSCAC15_06685 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BtSCAC15_06710 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BtSCAC15_06715 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BtSCAC15_06735 ENOG4105C31 Tryptophanyl-tRNA synthetase BtSCAC15_06755 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BtSCAC15_06760 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BtSCAC15_06770 ENOG4108JQ7 (ABC) transporter BtSCAC15_06775 ENOG4105UQX Mate efflux family protein BtSCAC15_06800 ENOG4108ZCF integral membrane protein BtSCAC15_06810 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BtSCAC15_06820 ENOG4105DPN Oligoendopeptidase f BtSCAC15_06835 ENOG4108Z18 K06886 hemoglobin BtSCAC15_06840 ENOG4105MIX Adenylate cyclase BtSCAC15_06845 ENOG4106EFP UPF0738 protein BtSCAC15_06855 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BtSCAC15_06860 ENOG4105EMS pseudouridine synthase BtSCAC15_06880 ENOG4105K64 Glycosyl transferase, family 2 BtSCAC15_06900 ENOG4107TVC Glycosyl transferase, family 2 BtSCAC15_06925 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BtSCAC15_06930 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BtSCAC15_06940 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BtSCAC15_06990 ENOG4108ZMI UPF0477 protein BtSCAC15_07020 ENOG4105CK7 Sodium proline symporter BtSCAC15_07030 ENOG4105CRQ synthase (Component I) BtSCAC15_07035 ENOG4105DDQ anthranilate synthase BtSCAC15_07045 ENOG4105DK0 Indole-3-glycerol phosphate synthase BtSCAC15_07055 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BtSCAC15_07060 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) BtSCAC15_07130 ENOG4105C7S Dehydrogenase BtSCAC15_07140 ENOG4105VZ8 Transcriptional regulator BtSCAC15_07195 ENOG4105DZ1 carboxypeptidase BtSCAC15_07200 ENOG4105VFR signal peptidase BtSCAC15_07235 ENOG4105C26 Dehydrogenase BtSCAC15_07240 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BtSCAC15_07245 ENOG4105F38 ABC transporter, permease BtSCAC15_07250 ENOG4105D38 putrescine abc transporter BtSCAC15_07255 ENOG4107RUE extracellular solute-binding protein family 1 BtSCAC15_07265 ENOG4105EYF MMPL domain protein BtSCAC15_07275 ENOG4108YBP pseudouridine synthase BtSCAC15_07285 ENOG4105K4I Scp-like extracellular BtSCAC15_07290 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BtSCAC15_07295 ENOG4105CQB FAD linked oxidase domain protein BtSCAC15_07310 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_07315 ENOG4105BZU Histidine kinase BtSCAC15_07320 ENOG4105JXH GntR family transcriptional regulator BtSCAC15_07340 ENOG4106A3R peptidase BtSCAC15_07350 ENOG4108QTI )-transporter BtSCAC15_07355 ENOG4107TS3 membrane protein, TerC BtSCAC15_07360 ENOG4105CZN Potassium uptake protein BtSCAC15_07365 ENOG410681C small acid-soluble spore protein BtSCAC15_07370 ENOG4108Z7G MaoC domain protein dehydratase BtSCAC15_07390 ENOG4105CHR reductase BtSCAC15_07430 ENOG4105C4Y ABC transporter BtSCAC15_07435 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BtSCAC15_07440 ENOG4107RCV ABC transporter, permease BtSCAC15_07460 ENOG4105E98 transcriptional regulator DeoR family BtSCAC15_07475 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BtSCAC15_07485 ENOG4105PXI polysaccharide deacetylase BtSCAC15_07495 ENOG4105BZU Histidine kinase BtSCAC15_07500 ENOG41090MY MarR family Transcriptional regulator BtSCAC15_07510 ENOG4106DF1 BtSCAC15_07520 ENOG4105BZU Histidine kinase BtSCAC15_07525 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BtSCAC15_07530 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BtSCAC15_07535 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BtSCAC15_07585 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BtSCAC15_07590 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BtSCAC15_07600 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BtSCAC15_07605 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BtSCAC15_07615 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BtSCAC15_07620 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BtSCAC15_07625 ENOG4105CZV ABC transporter BtSCAC15_07635 ENOG4105CJ1 ABC, transporter BtSCAC15_07675 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BtSCAC15_07680 ENOG4105EA8 2-Nitropropane dioxygenase BtSCAC15_07685 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BtSCAC15_07695 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BtSCAC15_07720 ENOG4105NQC Flavodoxin BtSCAC15_07755 ENOG4106050 phage regulatory protein, rha family BtSCAC15_07820 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BtSCAC15_07905 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BtSCAC15_07935 ENOG4105CZN Potassium uptake protein BtSCAC15_07940 ENOG41063Y9 BtSCAC15_07945 ENOG4105KBJ sporulation protein ytfj BtSCAC15_07975 ENOG4105CM2 brancheD-chain amino acid aminotransferase BtSCAC15_07980 ENOG4105C7K acetolactate synthase BtSCAC15_07985 ENOG4108ZP8 Acetolactate synthase small subunit BtSCAC15_07990 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BtSCAC15_08005 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BtSCAC15_08020 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BtSCAC15_08025 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BtSCAC15_08030 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BtSCAC15_08035 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BtSCAC15_08040 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase BtSCAC15_08045 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BtSCAC15_08050 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BtSCAC15_08055 ENOG4105KPZ phosphoribosyl-atp pyrophosphatase BtSCAC15_08060 ENOG4107RVV histidinol phosphate phosphatase, hisj family BtSCAC15_08075 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BtSCAC15_08080 ENOG4105E0M Sulfatase BtSCAC15_08090 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BtSCAC15_08110 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BtSCAC15_08115 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BtSCAC15_08125 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BtSCAC15_08130 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BtSCAC15_08135 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BtSCAC15_08150 ENOG4105C8J )-transporter BtSCAC15_08170 ENOG4105DFD Na H antiporter BtSCAC15_08190 ENOG4105ENE Histidine kinase BtSCAC15_08195 ENOG4105WH1 Two component transcriptional regulator luxr family BtSCAC15_08215 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BtSCAC15_08240 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BtSCAC15_08265 ENOG4105CJ3 phosphate transporter BtSCAC15_08270 ENOG4107GRR phosphate transport regulator BtSCAC15_08275 ENOG4105BZ4 penicillin-binding protein BtSCAC15_08290 ENOG4105BZU Histidine kinase BtSCAC15_08295 ENOG4105I3N Conserved Protein BtSCAC15_08310 ENOG4105BZU Histidine kinase BtSCAC15_08315 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BtSCAC15_08340 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BtSCAC15_08345 ENOG4105DZ1 carboxypeptidase BtSCAC15_08350 ENOG4108JIC nucleoside recognition domain protein BtSCAC15_08360 ENOG4105FE9 pseudouridine synthase BtSCAC15_08365 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BtSCAC15_08370 ENOG4107TWT Cytochrome c biogenesis protein BtSCAC15_08375 ENOG4105CRE cytochrome C BtSCAC15_08380 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_08385 ENOG4105BZU Histidine kinase BtSCAC15_08390 ENOG4108WBT adenosyltransferase BtSCAC15_08405 ENOG4108SAX Membrane BtSCAC15_08420 ENOG4105C9U ATP-dependent DNA helicase RecQ BtSCAC15_08425 ENOG4105I7S Abortive infection protein BtSCAC15_08435 ENOG4107RGJ metallophosphoesterase BtSCAC15_08440 ENOG4108XDN Transcriptional regulator BtSCAC15_08445 ENOG4108S6Z Negative regulator of genetic competence BtSCAC15_08475 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BtSCAC15_08480 ENOG4107RB3 L-asparaginase BtSCAC15_08500 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BtSCAC15_08515 ENOG4105S2F BtSCAC15_08520 ENOG41065D1 BtSCAC15_08550 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BtSCAC15_08565 ENOG4105XXQ heptaprenyl diphosphate synthase component I BtSCAC15_08575 ENOG4105EAH synthase BtSCAC15_08580 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BtSCAC15_08585 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BtSCAC15_08590 ENOG4105D49 3-dehydroquinate synthase BtSCAC15_08600 ENOG41068YB TPR repeat-containing protein BtSCAC15_08615 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BtSCAC15_08620 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BtSCAC15_08655 ENOG4108JYZ YitT family BtSCAC15_08665 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BtSCAC15_08670 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BtSCAC15_08680 ENOG4105FJR Lmbe family BtSCAC15_08685 ENOG4105CPK Glycosyl transferase (Group 1 BtSCAC15_08710 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BtSCAC15_08715 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) BtSCAC15_08725 ENOG4105DVT helicase BtSCAC15_08730 ENOG4105YAC BtSCAC15_08750 ENOG4105CSM endonuclease III BtSCAC15_08760 ENOG4105BZ4 penicillin-binding protein BtSCAC15_08805 ENOG4106F55 Protein of unknown function (DUF1273) BtSCAC15_08820 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BtSCAC15_08830 ENOG4105DVT helicase BtSCAC15_08835 ENOG4105CTD carboxy-peptidase BtSCAC15_08845 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BtSCAC15_08850 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) BtSCAC15_08855 ENOG4105C2W permease BtSCAC15_08860 ENOG4105DHF Membrane BtSCAC15_08870 ENOG410890F Dynamin family BtSCAC15_08880 ENOG4108W0I acetyltransferase BtSCAC15_08945 ENOG4105HTX biosynthesis protein BtSCAC15_08975 ENOG4105CPK Glycosyl transferase (Group 1 BtSCAC15_08990 ENOG4108SZE gCN5-related N-acetyltransferase BtSCAC15_09010 ENOG41081VK Ribonuclease BtSCAC15_09075 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BtSCAC15_09085 ENOG4107RWR Sodium hydrogen exchanger BtSCAC15_09090 ENOG4105CN5 Metallo-Beta-Lactamase BtSCAC15_09100 ENOG4108Z5V transcriptional regulator, merr family BtSCAC15_09110 ENOG4105H67 Protein of unknown function (DUF421) BtSCAC15_09115 ENOG41080C8 DUF218 domain BtSCAC15_09150 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BtSCAC15_09160 ENOG4107R0U MotA TolQ exbB proton channel BtSCAC15_09165 ENOG4105ER2 Ompa motb domain protein BtSCAC15_09170 ENOG4107YTP response regulator receiver protein BtSCAC15_09175 ENOG4105CBS Chea signal transduction histidine kinase BtSCAC15_09180 ENOG4105DD5 Flagellar motor switch protein BtSCAC15_09195 ENOG4105BZU Histidine kinase BtSCAC15_09215 ENOG4105E1Q flagellar hook-associated protein BtSCAC15_09220 ENOG4105DTJ flagellar hook-associated protein BtSCAC15_09240 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BtSCAC15_09245 ENOG4108ZC9 flagellar basal-body rod protein flgc BtSCAC15_09250 ENOG41075Z6 flagellar hook-basal body complex protein fliE BtSCAC15_09255 ENOG4107U2N Flagellar M-ring protein BtSCAC15_09260 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BtSCAC15_09290 ENOG4105BZE flagellar hook protein, FlgE BtSCAC15_09305 ENOG4107R88 Chemotaxis protein (CheV) BtSCAC15_09315 ENOG4105I03 Flagellin BtSCAC15_09320 ENOG4105I03 Flagellin BtSCAC15_09325 ENOG4105E4C Lytic transglycosylase catalytic BtSCAC15_09335 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BtSCAC15_09340 ENOG4105DD5 Flagellar motor switch protein BtSCAC15_09350 ENOG4105CN7 Flagellar biosynthetic protein FliP BtSCAC15_09355 ENOG4105VS8 Flagellar biosynthetic protein fliq BtSCAC15_09365 ENOG4105D00 flagellar biosynthetic protein flhB BtSCAC15_09370 ENOG4105D7B Flagellar biosynthesis protein flha BtSCAC15_09375 ENOG4105FZW flagellar biosynthesis regulator FlhF BtSCAC15_09380 ENOG4105KTQ flagellar basal-body rod protein BtSCAC15_09385 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BtSCAC15_09420 ENOG4105KAC Antibiotic biosynthesis monooxygenase BtSCAC15_09445 ENOG4105DUM transcriptional regulator, lysR family BtSCAC15_09495 ENOG4105CVJ phosphoglycerate mutase BtSCAC15_09505 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BtSCAC15_09525 ENOG4105CAQ asparagine synthetase BtSCAC15_09545 ENOG4105PGM cation diffusion facilitator family transporter BtSCAC15_09555 ENOG4105DRR Transcriptional regulator, GntR family BtSCAC15_09560 ENOG4108UZ3 Transporter BtSCAC15_09570 ENOG4105CKI cobalamin synthesis protein BtSCAC15_09575 ENOG4108PJD permease BtSCAC15_09590 ENOG4105DFD Na H antiporter BtSCAC15_09595 ENOG4105VUF Transcriptional regulator BtSCAC15_09605 ENOG4105C9Q fumarate hydratase class II BtSCAC15_09620 ENOG4107QJQ Mate efflux family protein BtSCAC15_09625 ENOG4105EC3 peptidase S51, dipeptidase E BtSCAC15_09645 ENOG4107QIV Cytochrome c biogenesis protein BtSCAC15_09665 ENOG4105BZC d-serine deaminase BtSCAC15_09670 ENOG4106BRA Membrane BtSCAC15_09710 ENOG4105CJ1 ABC, transporter BtSCAC15_09730 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BtSCAC15_09740 ENOG4108IJ0 Aspartate ammonia-lyase BtSCAC15_09745 ENOG4105C6K Malic enzyme BtSCAC15_09795 ENOG4105DQ6 Transposase BtSCAC15_09815 ENOG4105CSR polyphosphate kinase 2 BtSCAC15_09820 ENOG4105U3E Transcriptional regulator BtSCAC15_09835 ENOG4105DXI Major Facilitator superfamily BtSCAC15_09850 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BtSCAC15_09855 ENOG4105EU0 Major facilitator Superfamily BtSCAC15_09860 ENOG4105C6T cysteine synthase BtSCAC15_09880 ENOG4105C8J )-transporter BtSCAC15_09890 ENOG4105X5K response regulator receiver protein BtSCAC15_09895 ENOG4105H67 Protein of unknown function (DUF421) BtSCAC15_09925 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BtSCAC15_09930 ENOG4105CHR reductase BtSCAC15_09935 ENOG4105CM2 brancheD-chain amino acid aminotransferase BtSCAC15_09940 ENOG4105C7K acetolactate synthase BtSCAC15_09950 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BtSCAC15_09955 ENOG4105C01 Dihydroxy-acid dehydratase BtSCAC15_09960 ENOG4105C7B Threonine dehydratase BtSCAC15_09985 ENOG4105C6X Major Facilitator BtSCAC15_09990 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BtSCAC15_10000 ENOG4105DY9 regulatoR BtSCAC15_10005 ENOG4105CYC Transferase BtSCAC15_10020 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BtSCAC15_10030 ENOG41068WN BtSCAC15_10035 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BtSCAC15_10040 ENOG4105C72 UPF0176 protein BtSCAC15_10050 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BtSCAC15_10055 ENOG4105C0X amino acid BtSCAC15_10095 ENOG410849A acetyltransferase, (GNAT) family BtSCAC15_10105 ENOG4105K8R UPF0145 protein BtSCAC15_10120 ENOG4107RHR regulatoR BtSCAC15_10130 ENOG4105D9N nucleoside BtSCAC15_10135 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BtSCAC15_10160 ENOG4107RAQ aminopeptidase BtSCAC15_10170 ENOG4107R16 Multicopper oxidase BtSCAC15_10190 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BtSCAC15_10205 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BtSCAC15_10220 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_10245 ENOG4105DQ6 Transposase BtSCAC15_10255 ENOG4105BZU Histidine kinase BtSCAC15_10260 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_10265 ENOG4105EDW glycosyl transferase, family 39 BtSCAC15_10270 ENOG4105CKK Glycosyl transferase, family 2 BtSCAC15_10290 ENOG4105C19 ABC transporter BtSCAC15_10295 ENOG4107RBB ABC transporter, permease BtSCAC15_10325 ENOG4108T5E Copper resistance protein BtSCAC15_10330 ENOG4105KTB nuclear export factor GLE1 BtSCAC15_10335 ENOG4107RT3 EamA-like transporter family BtSCAC15_10340 ENOG4105GZI Transcriptional regulator BtSCAC15_10345 ENOG4108Z40 Transcriptional regulator BtSCAC15_10350 ENOG4107ZXU DSBA oxidoreductase BtSCAC15_10355 ENOG4108TVJ Nitroreductase BtSCAC15_10365 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BtSCAC15_10370 ENOG4106F5Q Membrane BtSCAC15_10375 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BtSCAC15_10390 ENOG4105CKI cobalamin synthesis protein BtSCAC15_10400 ENOG4105C0Z ABC transporter BtSCAC15_10405 ENOG4108IV0 ABC, transporter BtSCAC15_10410 ENOG4105C32 Amino acid ABC transporter (Permease) BtSCAC15_10420 ENOG4105SKE transcriptional Regulator LysR family BtSCAC15_10430 ENOG4105MDS 4-oxalocrotonate tautomerase BtSCAC15_10450 ENOG4105C4M (Ubiquinol oxidase) subunit I BtSCAC15_10455 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BtSCAC15_10460 ENOG4108JJ9 ABC, transporter BtSCAC15_10465 ENOG4108JJ8 (ABC) transporter BtSCAC15_10475 ENOG4105K64 Glycosyl transferase, family 2 BtSCAC15_10485 ENOG4108UT6 Transferase hexapeptide repeat containing protein BtSCAC15_10545 ENOG4105BZ1 (ABC) transporter BtSCAC15_10550 ENOG4105EFI regulatoR BtSCAC15_10555 ENOG4105BZU Histidine kinase BtSCAC15_10570 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BtSCAC15_10575 ENOG4108ZJ4 polysaccharide deacetylase BtSCAC15_10595 ENOG4105D6E homoserine dehydrogenase BtSCAC15_10605 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BtSCAC15_10630 ENOG4108KGH TRANSCRIPTIONal BtSCAC15_10640 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BtSCAC15_10645 ENOG4105BZU Histidine kinase BtSCAC15_10650 ENOG4107VMI polysaccharide deacetylase BtSCAC15_10660 ENOG4105KT7 mgtC SapB transporter BtSCAC15_10665 ENOG4105VRR gCN5-related N-acetyltransferase BtSCAC15_10675 ENOG4105DUU IucA IucC family protein BtSCAC15_10680 ENOG4105CEY Amp-dependent synthetase and ligase BtSCAC15_10695 ENOG4108WBH protein TIM barrel BtSCAC15_10700 ENOG4105YWU small acid-soluble spore protein BtSCAC15_10710 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BtSCAC15_10715 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BtSCAC15_10765 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_10775 ENOG4105YVS arsR family transcriptional regulator BtSCAC15_10780 ENOG4105CPC Aldo Keto reductase BtSCAC15_10785 ENOG4107XZQ multidrug resistance protein BtSCAC15_10810 ENOG4105C8Q Methyl-accepting chemotaxis BtSCAC15_10840 ENOG4108K88 Membrane BtSCAC15_10845 ENOG4108WPJ Ferritin-like domain BtSCAC15_10860 ENOG4105DEN Luciferase family BtSCAC15_10875 ENOG4105VMI -acetyltransferase BtSCAC15_10880 ENOG4107QM2 Aldo Keto reductase BtSCAC15_10885 ENOG4105CKI cobalamin synthesis protein BtSCAC15_10895 ENOG4105DSE periplasmic solute binding protein BtSCAC15_10905 ENOG4105K4T epimerase BtSCAC15_10910 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BtSCAC15_10915 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BtSCAC15_10945 ENOG4105DQ6 Transposase BtSCAC15_10975 ENOG4107T5V SNARE associated Golgi BtSCAC15_10990 ENOG4108PJD permease BtSCAC15_11000 ENOG4108S4H thioesterase Superfamily protein BtSCAC15_11010 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BtSCAC15_11030 ENOG4105SXS Protein of unknown function (DUF456) BtSCAC15_11035 ENOG4105C37 (CBS) domain BtSCAC15_11055 ENOG4108Z7R Chaperone CsaA BtSCAC15_11075 ENOG4108ZRV stage ii sporulation protein p BtSCAC15_11085 ENOG4108VXD carboxy-peptidase BtSCAC15_11095 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BtSCAC15_11125 ENOG4108X4Q Hydrolase BtSCAC15_11140 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BtSCAC15_11160 ENOG41087PP glycosyltransferase MGT family BtSCAC15_11165 ENOG4108JYZ YitT family BtSCAC15_11170 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BtSCAC15_11230 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) BtSCAC15_11235 ENOG4108MGT Required for secretion of EsxA and EsxB BtSCAC15_11300 ENOG4105KBJ sporulation protein ytfj BtSCAC15_11325 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BtSCAC15_11345 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BtSCAC15_11350 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BtSCAC15_11360 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BtSCAC15_11365 ENOG4105EMN RNA polymerase sigma factor BtSCAC15_11380 ENOG4105CNW domain protein BtSCAC15_11390 ENOG4108V06 Glutathione peroxidase BtSCAC15_11405 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BtSCAC15_11415 ENOG4108IUE nitrate reductase beta subunit BtSCAC15_11420 ENOG4105R3A Nitrate reductase BtSCAC15_11430 ENOG4107V6Q Cyclic nucleotide-binding domain BtSCAC15_11435 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BtSCAC15_11440 ENOG4105D06 uba thif-type nad fad binding protein BtSCAC15_11445 ENOG4105CVM Molybdenum cofactor synthesis domain protein BtSCAC15_11450 ENOG4108ZAF Molybdopterin BtSCAC15_11475 ENOG4105DQ6 Transposase BtSCAC15_11500 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BtSCAC15_11505 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BtSCAC15_11510 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BtSCAC15_11515 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BtSCAC15_11520 ENOG4108IFG nitrite reductase, (NAD(P)H) BtSCAC15_11525 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BtSCAC15_11565 ENOG4105MCT stage V sporulation protein S BtSCAC15_11595 ENOG4107TSN permease BtSCAC15_11620 ENOG4108FPN Integrase BtSCAC15_11645 ENOG4105C5H ABC transporter BtSCAC15_11660 ENOG4108UUM single-stranded DNA-binding protein BtSCAC15_11680 ENOG4107YX5 Pfam:DUF548 BtSCAC15_11685 ENOG4105C75 arginyL-tRNA synthetase BtSCAC15_11710 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BtSCAC15_11740 ENOG4105C5S asparaginyl-tRNA synthetase BtSCAC15_11745 ENOG4105C8J )-transporter BtSCAC15_11765 ENOG4107XGZ Hydrolase BtSCAC15_11770 ENOG4105CY2 Citrate transporter BtSCAC15_11790 ENOG4105KD7 acetyltransferase BtSCAC15_11800 ENOG4105VMP Transcriptional regulator BtSCAC15_11805 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BtSCAC15_11830 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BtSCAC15_11845 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BtSCAC15_11850 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BtSCAC15_11860 ENOG4107RVG penicillin-binding protein BtSCAC15_11865 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BtSCAC15_11870 ENOG4105E9Q Acyl-transferase BtSCAC15_11875 ENOG4108UT2 hemolysin iii BtSCAC15_11885 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BtSCAC15_11895 ENOG4108RCR degv family BtSCAC15_11905 ENOG4108KF3 Electron transport protein SCO1 SenC BtSCAC15_11910 ENOG4107Y70 Heat shock protein BtSCAC15_11915 ENOG4105CAQ asparagine synthetase BtSCAC15_11930 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BtSCAC15_11935 ENOG4108MES Periplasmic binding protein BtSCAC15_11940 ENOG4105F0I Aminotransferase BtSCAC15_11975 ENOG4105D8X mechanosensitive ion channel BtSCAC15_11980 ENOG4105BZU Histidine kinase BtSCAC15_11985 ENOG4105WH1 Two component transcriptional regulator luxr family BtSCAC15_11990 ENOG4106KNT transcriptional regulator BtSCAC15_11995 ENOG4107ZY0 Phenazine biosynthesis-like protein BtSCAC15_12015 ENOG4105CMG Carbohydrate kinase BtSCAC15_12020 ENOG4105C6Z Gluconate BtSCAC15_12030 ENOG4108YV3 Protein of unknown function (DUF2711) BtSCAC15_12065 ENOG4108IJ8 ABC transporter BtSCAC15_12070 ENOG4105E90 ABC transporter BtSCAC15_12105 ENOG4105C37 (CBS) domain BtSCAC15_12130 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BtSCAC15_12145 ENOG4107S4Y M20 DapE family protein YgeY BtSCAC15_12150 ENOG4108TSC N-acetyltransferase BtSCAC15_12155 ENOG4108JUB Transcriptional regulator BtSCAC15_12160 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BtSCAC15_12205 ENOG410841Q phosphoesterase PA-phosphatase related protein BtSCAC15_12215 ENOG4105SZ6 Thioredoxin BtSCAC15_12270 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BtSCAC15_12325 ENOG4105BZ4 penicillin-binding protein BtSCAC15_12335 ENOG4105CZM Major Facilitator BtSCAC15_12340 ENOG4105W8X HesB YadR YfhF-family protein BtSCAC15_12350 ENOG4105DXD 2-methylcitrate dehydratase BtSCAC15_12355 ENOG4105CR4 methylisocitrate lyase BtSCAC15_12360 ENOG4105C1G acyl-Coa dehydrogenase BtSCAC15_12365 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BtSCAC15_12375 ENOG4105N14 lysine exporter protein LysE YggA BtSCAC15_12380 ENOG4105E39 Enoyl-CoA hydratase BtSCAC15_12395 ENOG4107RFY SbcCD D subunit BtSCAC15_12400 ENOG4105EYH Exonuclease BtSCAC15_12430 ENOG4105FCD Major Facilitator BtSCAC15_12440 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BtSCAC15_12445 ENOG4105E4F Isochorismate synthase BtSCAC15_12450 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BtSCAC15_12455 ENOG4105WQI isochorismatase BtSCAC15_12460 ENOG4105CEY Amp-dependent synthetase and ligase BtSCAC15_12465 ENOG4105WQT MbtH domain protein BtSCAC15_12470 ENOG4105C0R drug resistance transporter emrb qaca subfamily BtSCAC15_12485 ENOG4105K70 DNA-binding protein BtSCAC15_12510 ENOG4105BZG amino acid carrier protein BtSCAC15_12530 ENOG4105FE9 pseudouridine synthase BtSCAC15_12535 ENOG4105C22 threonyL-tRNA synthetase BtSCAC15_12540 ENOG4105C19 ABC transporter BtSCAC15_12575 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BtSCAC15_12590 ENOG41081I9 integral membrane protein BtSCAC15_12600 ENOG4108Y4K DNA-binding transcriptional activator BtSCAC15_12625 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BtSCAC15_12635 ENOG4105EYF MMPL domain protein BtSCAC15_12685 ENOG4105WCN acetyltransferase BtSCAC15_12710 ENOG4105C1Q protoporphyrinogen oxidase BtSCAC15_12720 ENOG41068WN BtSCAC15_12755 ENOG4107V2S Transcriptional regulator BtSCAC15_12760 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BtSCAC15_12780 ENOG4105DND Transcriptional regulator BtSCAC15_12785 ENOG4108RPX mosc domain containing protein BtSCAC15_12800 ENOG4105BZ1 (ABC) transporter BtSCAC15_12805 ENOG4105BZ1 (ABC) transporter BtSCAC15_12845 ENOG4108JCI Transcriptional regulator BtSCAC15_12885 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BtSCAC15_12890 ENOG4108KPJ rna polymerase sigma factor BtSCAC15_12920 ENOG4105F32 YngK protein BtSCAC15_12940 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) BtSCAC15_12945 ENOG4105RD7 BadF BadG BcrA BcrD BtSCAC15_12950 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BtSCAC15_12955 ENOG4107STF Involved in phosphonate degradation (By similarity) BtSCAC15_12960 ENOG4105C7B Threonine dehydratase BtSCAC15_12965 ENOG4108INS Transcriptional regulator BtSCAC15_12990 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BtSCAC15_13000 ENOG4105C1J atp-dependent rna helicase BtSCAC15_13020 ENOG4108RZE Tetr family transcriptional regulator BtSCAC15_13065 ENOG41088CC tellurite resistance protein tehB BtSCAC15_13075 ENOG4108I0C methyltransferase BtSCAC15_13080 ENOG4107RA9 decarboxylase BtSCAC15_13085 ENOG4105K56 Transcriptional regulator BtSCAC15_13090 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BtSCAC15_13125 ENOG4105CIN aminoacyl-histidine dipeptidase BtSCAC15_13150 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_13160 ENOG4105EJ9 Membrane BtSCAC15_13165 ENOG4105EQK -acetyltransferase BtSCAC15_13315 ENOG4105ED2 Beta-lactamase BtSCAC15_13345 ENOG4105FQP Beta-lactamase BtSCAC15_13350 ENOG4107RVG penicillin-binding protein BtSCAC15_13365 ENOG4107RF6 penicillin-binding protein BtSCAC15_13370 ENOG4107RF6 penicillin-binding protein BtSCAC15_13380 ENOG4105DIN metallophosphoesterase BtSCAC15_13390 ENOG4105CJ1 ABC, transporter BtSCAC15_13400 ENOG4107Z3H Transcriptional regulator, TetR family BtSCAC15_13420 ENOG4105C1G acyl-Coa dehydrogenase BtSCAC15_13425 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BtSCAC15_13430 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BtSCAC15_13435 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BtSCAC15_13440 ENOG4105E39 Enoyl-CoA hydratase BtSCAC15_13445 ENOG4107QX3 carboxylase BtSCAC15_13450 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BtSCAC15_13475 ENOG4105DBI uridine monophosphokinase BtSCAC15_13495 ENOG4105DZ1 carboxypeptidase BtSCAC15_13510 ENOG4105T9C HD domain BtSCAC15_13520 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BtSCAC15_13540 ENOG41075H3 AraC family transcriptional regulator BtSCAC15_13570 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BtSCAC15_13580 ENOG4107Y80 Major Facilitator superfamily BtSCAC15_13585 ENOG4105CHR reductase BtSCAC15_13590 ENOG4105KVH Transcriptional regulator BtSCAC15_13645 ENOG4105DNP FAD linked oxidase domain protein BtSCAC15_13650 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BtSCAC15_13660 ENOG41069ER domain protein BtSCAC15_13710 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BtSCAC15_13720 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BtSCAC15_13725 ENOG4105CIH Imidazole acetol-phosphate transaminase BtSCAC15_13745 ENOG41082JN Transcriptional regulator BtSCAC15_13750 ENOG4105EYF MMPL domain protein BtSCAC15_13795 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BtSCAC15_13810 ENOG41061GT Aldolase BtSCAC15_13820 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BtSCAC15_13825 ENOG4105DKT Transcriptional regulator BtSCAC15_13835 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BtSCAC15_13840 ENOG4105F5R ABC transporter BtSCAC15_13845 ENOG4105D4B ABC, transporter BtSCAC15_13860 ENOG4105MKU Transcriptional regulator BtSCAC15_13865 ENOG4105EFA 4-hydroxyphenylacetate BtSCAC15_13880 ENOG4105CPQ Dehydrogenase BtSCAC15_13890 ENOG410900G Protein of unknown function (DUF421) BtSCAC15_13900 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BtSCAC15_13910 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BtSCAC15_13920 ENOG4105DK7 lysyl-tRNA synthetase BtSCAC15_13930 ENOG4108VQT Alpha beta hydrolase fold protein BtSCAC15_13970 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BtSCAC15_14005 ENOG4105D6E homoserine dehydrogenase BtSCAC15_14015 ENOG4105CPF Cell wall formation (By similarity) BtSCAC15_14020 ENOG4105ETU transcriptional activator (TenA BtSCAC15_14130 ENOG410667J hydrolase BtSCAC15_14135 ENOG4105BZU Histidine kinase BtSCAC15_14140 ENOG4107RF6 penicillin-binding protein BtSCAC15_14190 ENOG4108HGU Histidine kinase BtSCAC15_14235 ENOG4105CB2 alcohol dehydrogenase BtSCAC15_14240 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BtSCAC15_14245 ENOG4105CJN penicillin-binding protein BtSCAC15_14295 ENOG4107SFI Major Facilitator superfamily BtSCAC15_14300 ENOG4108Z5V transcriptional regulator, merr family BtSCAC15_14325 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BtSCAC15_14350 ENOG4107Y9U Membrane BtSCAC15_14420 ENOG4105E09 nadh pyrophosphatase BtSCAC15_14425 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BtSCAC15_14445 ENOG4105KME endoribonuclease L-psp BtSCAC15_14450 ENOG4108XI2 Domain of unknown function (DUF1963) BtSCAC15_14480 ENOG4108NRW Phospholipase, patatin family BtSCAC15_14495 ENOG4108YYS metal-dependent hydrolase (By similarity) BtSCAC15_14510 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BtSCAC15_14520 ENOG4105PKS Excinuclease abc c subunit domain protein BtSCAC15_14550 ENOG4105CJ1 ABC, transporter BtSCAC15_14580 ENOG4107VFR oxidoreductase BtSCAC15_14620 ENOG4105U0R haloacid dehalogenase-like hydrolase BtSCAC15_14625 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_14630 ENOG4105BZU Histidine kinase BtSCAC15_14650 ENOG4107WD8 ABC transporter, permease BtSCAC15_14665 ENOG4105DY8 decarboxylase BtSCAC15_14680 ENOG4108IUM Glycogen debranching enzyme BtSCAC15_14690 ENOG4105CGH 5'-nucleotidase BtSCAC15_14710 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BtSCAC15_14715 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BtSCAC15_14720 ENOG4105FDR Membrane BtSCAC15_14730 ENOG4105CIS alcohol dehydrogenase BtSCAC15_14735 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BtSCAC15_14780 ENOG4105MSI germination protein ypeb BtSCAC15_14810 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BtSCAC15_14815 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BtSCAC15_14820 ENOG4107Z3H Transcriptional regulator, TetR family BtSCAC15_14850 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BtSCAC15_14870 ENOG4105E98 transcriptional regulator DeoR family BtSCAC15_14885 ENOG41062ES Transcriptional regulator BtSCAC15_14905 ENOG4107QKR Dehydrogenase BtSCAC15_14915 ENOG4107RUY (E1 component), alpha subunit BtSCAC15_14925 ENOG4105E1F short-chain dehydrogenase reductase BtSCAC15_14955 ENOG4107SQ8 Glycine betaine BtSCAC15_14960 ENOG4108IJ7 Glycine betaine BtSCAC15_14985 ENOG4105E66 phosphoriboisomerase A BtSCAC15_14990 ENOG41082BV acetyltransferase BtSCAC15_14995 ENOG4108M1A Chitin-binding protein BtSCAC15_15025 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BtSCAC15_15030 ENOG4105MSB protein, conserved in bacteria BtSCAC15_15050 ENOG4108Z7F N-acetyltransferase BtSCAC15_15070 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BtSCAC15_15075 ENOG4105EEM helicase BtSCAC15_15090 ENOG4105C9U ATP-dependent DNA helicase RecQ BtSCAC15_15145 ENOG4108M1A Chitin-binding protein BtSCAC15_15165 ENOG4105BZG amino acid carrier protein BtSCAC15_15170 ENOG4105C26 Dehydrogenase BtSCAC15_15175 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BtSCAC15_15185 ENOG4105CTU Proline racemase BtSCAC15_15190 ENOG4105CTU Proline racemase BtSCAC15_15195 ENOG41080HI glycine oxidase BtSCAC15_15205 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BtSCAC15_15240 ENOG4105DCI Phosphohydrolase BtSCAC15_15245 ENOG4107T5V SNARE associated Golgi BtSCAC15_15255 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BtSCAC15_15270 ENOG4105DQ6 Transposase BtSCAC15_15290 ENOG4105DTQ mandelate racemase muconate lactonizing BtSCAC15_15305 ENOG4107SET aldo keto reductase BtSCAC15_15345 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BtSCAC15_15350 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BtSCAC15_15355 ENOG4105BZU Histidine kinase BtSCAC15_15360 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_15380 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BtSCAC15_15395 ENOG4105DPN Oligoendopeptidase f BtSCAC15_15400 ENOG4105EPR degv family BtSCAC15_15465 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BtSCAC15_15470 ENOG4106K7D Major facilitator family transporter BtSCAC15_15490 ENOG4107BMA Transglycosylase associated protein BtSCAC15_15505 ENOG41089UC methyltransferase, type 11 BtSCAC15_15545 ENOG4105CHM Aminotransferase BtSCAC15_15575 ENOG4105DVE abc transporter atp-binding protein BtSCAC15_15630 ENOG4105C02 permease BtSCAC15_15645 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BtSCAC15_15650 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BtSCAC15_15655 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BtSCAC15_15660 ENOG4105D7T ABC transporter BtSCAC15_15695 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BtSCAC15_15735 ENOG4107VC0 DNA alkylation repair enzyme BtSCAC15_15740 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BtSCAC15_15750 ENOG4107VMI polysaccharide deacetylase BtSCAC15_15760 ENOG4108ZCF integral membrane protein BtSCAC15_15765 ENOG4105E0M Sulfatase BtSCAC15_15770 ENOG4105C5H ABC transporter BtSCAC15_15790 ENOG4105EYF MMPL domain protein BtSCAC15_15795 ENOG41082JN Transcriptional regulator BtSCAC15_15815 ENOG4105CIH Imidazole acetol-phosphate transaminase BtSCAC15_15820 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BtSCAC15_15830 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BtSCAC15_15880 ENOG41069ER domain protein BtSCAC15_15890 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BtSCAC15_15895 ENOG4105DNP FAD linked oxidase domain protein BtSCAC15_15950 ENOG4105KVH Transcriptional regulator BtSCAC15_15955 ENOG4105CHR reductase BtSCAC15_15960 ENOG4107Y80 Major Facilitator superfamily BtSCAC15_15970 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BtSCAC15_16000 ENOG41075H3 AraC family transcriptional regulator BtSCAC15_16020 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BtSCAC15_16030 ENOG4105T9C HD domain BtSCAC15_16045 ENOG4105DZ1 carboxypeptidase BtSCAC15_16065 ENOG4105DBI uridine monophosphokinase BtSCAC15_16095 ENOG410900G Protein of unknown function (DUF421) BtSCAC15_16105 ENOG4105CPQ Dehydrogenase BtSCAC15_16120 ENOG4105EFA 4-hydroxyphenylacetate BtSCAC15_16125 ENOG4105MKU Transcriptional regulator BtSCAC15_16140 ENOG4105D4B ABC, transporter BtSCAC15_16145 ENOG4105F5R ABC transporter BtSCAC15_16150 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BtSCAC15_16160 ENOG4105DKT Transcriptional regulator BtSCAC15_16165 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BtSCAC15_16175 ENOG41061GT Aldolase BtSCAC15_16190 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BtSCAC15_16240 ENOG4105II7 pyrroline-5-carboxylate reductase BtSCAC15_16250 ENOG4107258 Transcriptional regulator BtSCAC15_16275 ENOG4105ECK Fatty Acid Desaturase BtSCAC15_16285 ENOG4107RBI VanW family BtSCAC15_16290 ENOG4105G6Z alkaline phosphatase BtSCAC15_16300 ENOG4105VMP Transcriptional regulator BtSCAC15_16350 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BtSCAC15_16375 ENOG4105CKK Glycosyl transferase, family 2 BtSCAC15_16405 ENOG4105C8Y Acetylornithine aminotransferase BtSCAC15_16450 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BtSCAC15_16475 ENOG4108IBT Inherit from COG: transposase BtSCAC15_16495 ENOG4108TVJ Nitroreductase BtSCAC15_16500 ENOG4105FS7 Transcriptional regulator BtSCAC15_16535 ENOG4105CMR udp-glucose 4-epimerase BtSCAC15_16545 ENOG4108DMH HTH_ARAC BtSCAC15_16550 ENOG4108FWV Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BtSCAC15_16555 ENOG4108XET gCN5-related N-acetyltransferase BtSCAC15_16570 ENOG4108PCN EamA-like transporter family BtSCAC15_16600 ENOG4107XJU UPF0178 protein BtSCAC15_16640 ENOG410635A Membrane BtSCAC15_16650 ENOG4108IQI permease BtSCAC15_16660 ENOG4105F1N DNA alkylation repair BtSCAC15_16670 ENOG4105BZU Histidine kinase BtSCAC15_16675 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_16685 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BtSCAC15_16720 ENOG4107RF6 penicillin-binding protein BtSCAC15_16725 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BtSCAC15_16745 ENOG4105E7W lamb ycsf family protein BtSCAC15_16755 ENOG4105P4J Allophanate hydrolase, subunit 1 BtSCAC15_16760 ENOG4107258 Transcriptional regulator BtSCAC15_16770 ENOG4106N3A copper homeostasis protein cutc BtSCAC15_16775 ENOG4108ZHR arsR family transcriptional regulator BtSCAC15_16790 ENOG4105FDT acyl-CoA dehydrogenase BtSCAC15_16805 ENOG4105DWD nucleoside recognition domain protein BtSCAC15_16850 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BtSCAC15_16865 ENOG4105CUB amino acid BtSCAC15_16870 ENOG4105II7 pyrroline-5-carboxylate reductase BtSCAC15_16875 ENOG4108NHD germination protein BtSCAC15_16880 ENOG4108Q8B Spore germination protein BtSCAC15_16920 ENOG4106A3M Cytochrome p-450 BtSCAC15_16935 ENOG4105CGH 5'-nucleotidase BtSCAC15_16945 ENOG4105CHJ isochorismatase hydrolase BtSCAC15_16970 ENOG41090MY MarR family Transcriptional regulator BtSCAC15_17015 ENOG4105F6J Alpha beta hydrolase fold BtSCAC15_17030 ENOG4108606 TspO/MBR family BtSCAC15_17035 ENOG4105CVP deoxyribo-dipyrimidine photolyase BtSCAC15_17060 ENOG4108TWJ NADH dehydrogenase subunit 5 BtSCAC15_17065 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BtSCAC15_17075 ENOG4108Q5U germination protein, ger(x)c family BtSCAC15_17080 ENOG4105E1K spore germination protein BtSCAC15_17085 ENOG4107VMI polysaccharide deacetylase BtSCAC15_17090 ENOG4105KY5 gCN5-related N-acetyltransferase BtSCAC15_17095 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BtSCAC15_17105 ENOG4105Z7P Acetyltransferase (GNAT) family BtSCAC15_17115 ENOG4105D6J arsenicaL-resistance protein BtSCAC15_17120 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BtSCAC15_17125 ENOG41085FC arsR family transcriptional regulator BtSCAC15_17140 ENOG4105DQ6 Transposase BtSCAC15_17150 ENOG4105NAE bifunctional deaminase-reductase domain protein BtSCAC15_17155 ENOG4107P5I polyketide synthase BtSCAC15_17160 ENOG4108IG5 Transcriptional regulator BtSCAC15_17175 ENOG4105EQ0 Major Facilitator superfamily BtSCAC15_17180 ENOG4108JGH Tetr family transcriptional regulator BtSCAC15_17190 ENOG4105XRQ Xanthine dehydrogenase accessory factor BtSCAC15_17235 ENOG4105CHR reductase BtSCAC15_17240 ENOG4108YXU transcriptional regulator AsnC family BtSCAC15_17310 ENOG4105C44 Serine transporter BtSCAC15_17315 ENOG4105DUM transcriptional regulator, lysR family BtSCAC15_17320 ENOG4105DWP Membrane BtSCAC15_17370 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_17375 ENOG41062D9 Histidine kinase BtSCAC15_17425 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BtSCAC15_17430 ENOG4105C0R drug resistance transporter emrb qaca subfamily BtSCAC15_17455 ENOG4105K6H D-cysteine desulfhydrase BtSCAC15_17465 ENOG4105E0Y RtcB Protein BtSCAC15_17475 ENOG4105JQZ Methyltransferase BtSCAC15_17495 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BtSCAC15_17515 ENOG4105BZU Histidine kinase BtSCAC15_17525 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BtSCAC15_17535 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BtSCAC15_17580 ENOG4105C44 Serine transporter BtSCAC15_17585 ENOG4105EJQ L-serine dehydratase BtSCAC15_17610 ENOG4108JPW Aminotransferase BtSCAC15_17625 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BtSCAC15_17635 ENOG4105DVH amino acid BtSCAC15_17660 ENOG4108JQ1 Dehydrogenase BtSCAC15_17665 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BtSCAC15_17680 ENOG41082W1 Cupin 2, conserved barrel domain protein BtSCAC15_17700 ENOG4105DQ6 Transposase BtSCAC15_17725 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BtSCAC15_17845 ENOG4108VXD carboxy-peptidase BtSCAC15_17850 ENOG4105PNM synthesis protein BtSCAC15_17860 ENOG4108ISG Major Facilitator BtSCAC15_17875 ENOG4107MII Sugar-specific transcriptional regulator TrmB BtSCAC15_17880 ENOG4105CZM Major Facilitator BtSCAC15_17890 ENOG4105CRW Short chain fatty acid transporter BtSCAC15_17900 ENOG4105DYS nad(p)h dehydrogenase (quinone) BtSCAC15_17960 ENOG4108K8S endonuclease I BtSCAC15_17980 ENOG4108Z66 YbaK ebsC protein BtSCAC15_17985 ENOG4105CUT histidyl-tRNA synthetase BtSCAC15_18000 ENOG4105KVH Transcriptional regulator BtSCAC15_18005 ENOG4108RCM Nitroreductase BtSCAC15_18015 ENOG4105CA9 Pyruvate kinase BtSCAC15_18045 ENOG4108PSK reductase BtSCAC15_18120 ENOG4105C31 Tryptophanyl-tRNA synthetase BtSCAC15_18135 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BtSCAC15_18170 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BtSCAC15_18180 ENOG4105EV4 Multidrug resistance protein mdtH BtSCAC15_18210 ENOG4105C37 (CBS) domain BtSCAC15_18230 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BtSCAC15_18235 ENOG4105FAW cDP-glucose 4,6-dehydratase BtSCAC15_18270 ENOG4105DDN Pentapeptide repeat-containing protein BtSCAC15_18275 ENOG4105XDF Protein of unknown function (DUF1272) BtSCAC15_18280 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BtSCAC15_18285 ENOG4105CMG Carbohydrate kinase BtSCAC15_18290 ENOG4105C6Z Gluconate BtSCAC15_18305 ENOG4105CV1 Transketolase (EC 2.2.1.1) BtSCAC15_18310 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BtSCAC15_18325 ENOG4105CIS alcohol dehydrogenase BtSCAC15_18330 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BtSCAC15_18350 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BtSCAC15_18370 ENOG4105C8Q Methyl-accepting chemotaxis BtSCAC15_18375 ENOG4108UX3 '-nucleotidase BtSCAC15_18385 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BtSCAC15_18390 ENOG4105KVH Transcriptional regulator BtSCAC15_18405 ENOG4105CV8 reductase BtSCAC15_18410 ENOG4105F27 Major Facilitator BtSCAC15_18420 ENOG41090KN UPF0303 protein BtSCAC15_18440 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BtSCAC15_18445 ENOG4105CHH sulfate transporter BtSCAC15_18460 ENOG4105C44 Serine transporter BtSCAC15_18500 ENOG4105KVH Transcriptional regulator BtSCAC15_18505 ENOG4108TZY GntR Family Transcriptional Regulator BtSCAC15_18510 ENOG4105D9R oxidoreductase BtSCAC15_18515 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BtSCAC15_18520 ENOG4105KVH Transcriptional regulator BtSCAC15_18525 ENOG4105KVH Transcriptional regulator BtSCAC15_18550 ENOG4105DQ6 Transposase BtSCAC15_18595 ENOG4105JAB phenazine biosynthesis protein, phzf family BtSCAC15_18605 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BtSCAC15_18610 ENOG4105KVH Transcriptional regulator BtSCAC15_18625 ENOG4108ZJ4 polysaccharide deacetylase BtSCAC15_18725 ENOG4105XSJ toxin secretion phage lysis holin BtSCAC15_18735 ENOG4105DQ6 Transposase BtSCAC15_18750 ENOG4105VTR Integrase BtSCAC15_18785 ENOG4105H3G oxidoreductase BtSCAC15_18860 ENOG4108TN2 lmbE family BtSCAC15_18870 ENOG4107R3E Citrate transporter BtSCAC15_18880 ENOG4105WCN acetyltransferase BtSCAC15_18885 ENOG4108MES Periplasmic binding protein BtSCAC15_18890 ENOG4105EHG Permease protein BtSCAC15_18895 ENOG4105DQ5 transport system permease protein BtSCAC15_18900 ENOG4105NX3 Membrane BtSCAC15_18920 ENOG41068WN BtSCAC15_18925 ENOG4107CUJ Protein of unknown function (DUF2690) BtSCAC15_18935 ENOG4107V2S Transcriptional regulator BtSCAC15_18955 ENOG4105C98 muts2 protein BtSCAC15_18965 ENOG4105E5K Alpha-amylase BtSCAC15_18970 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BtSCAC15_18975 ENOG4105DPN Oligoendopeptidase f BtSCAC15_18980 ENOG4108A04 Beta-lactamase BtSCAC15_19005 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BtSCAC15_19015 ENOG41082BM Transcriptional regulator, arsr family BtSCAC15_19020 ENOG4105CIS alcohol dehydrogenase BtSCAC15_19025 ENOG4105CNG UPF0061 protein BtSCAC15_19060 ENOG4105CQB FAD linked oxidase domain protein BtSCAC15_19090 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BtSCAC15_19105 ENOG4107TPS domain protein BtSCAC15_19110 ENOG4105CEP NADH dehydrogenase BtSCAC15_19120 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BtSCAC15_19130 ENOG4108IAJ Nad-dependent epimerase dehydratase BtSCAC15_19135 ENOG4105FAW cDP-glucose 4,6-dehydratase BtSCAC15_19225 ENOG4105DQ6 Transposase BtSCAC15_19265 ENOG4105BZU Histidine kinase BtSCAC15_19285 ENOG4105KT7 mgtC SapB transporter BtSCAC15_19295 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BtSCAC15_19300 ENOG41073R8 VanW family BtSCAC15_19310 ENOG4108R1P BtSCAC15_19330 ENOG4105VEQ Cold shock protein BtSCAC15_19370 ENOG410904N short-chain dehydrogenase reductase BtSCAC15_19380 ENOG4106IQC argininosuccinate lyase BtSCAC15_19395 ENOG4108IA2 Sodium pantothenate symporter BtSCAC15_19405 ENOG4105C26 Dehydrogenase BtSCAC15_19410 ENOG4105CHR reductase BtSCAC15_19420 ENOG4105EWU Squalene--hopene cyclase BtSCAC15_19430 ENOG4105FR1 rard protein BtSCAC15_19435 ENOG410696E Membrane BtSCAC15_19450 ENOG4105D1F ATP-binding protein BtSCAC15_19460 ENOG4108ZAF Molybdopterin BtSCAC15_19465 ENOG4105CVM Molybdenum cofactor synthesis domain protein BtSCAC15_19470 ENOG4105D06 uba thif-type nad fad binding protein BtSCAC15_19475 ENOG4105TMB Formate nitrite transporter BtSCAC15_19490 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BtSCAC15_19495 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BtSCAC15_19505 ENOG4108JB9 formate dehydrogenase BtSCAC15_19515 ENOG4105E1K spore germination protein BtSCAC15_19535 ENOG4105DQ6 Transposase BtSCAC15_19600 ENOG4108KGH TRANSCRIPTIONal BtSCAC15_19610 ENOG4105EMN RNA polymerase sigma factor BtSCAC15_19620 ENOG4105CIG ABC transporter BtSCAC15_19640 ENOG4105D9R oxidoreductase BtSCAC15_19650 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BtSCAC15_19660 ENOG4105K4P CoA-binding domain protein BtSCAC15_19665 ENOG4105C0H protease BtSCAC15_19670 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_19680 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BtSCAC15_19685 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BtSCAC15_19690 ENOG4105W8X HesB YadR YfhF-family protein BtSCAC15_19700 ENOG4105D7V transposase BtSCAC15_19725 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BtSCAC15_19730 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BtSCAC15_19745 ENOG4105BZ1 (ABC) transporter BtSCAC15_19750 ENOG4108I0Z Aconitate hydratase BtSCAC15_19780 ENOG4105E5W Transporter BtSCAC15_19790 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BtSCAC15_19810 ENOG4107F3J Amp-dependent synthetase and ligase BtSCAC15_19825 ENOG4107ZYJ bioY protein BtSCAC15_19830 ENOG4105CEY Amp-dependent synthetase and ligase BtSCAC15_19875 ENOG4107AYK membrAne BtSCAC15_19890 ENOG4105BZU Histidine kinase BtSCAC15_19895 ENOG4105FBA Phospholipase Carboxylesterase BtSCAC15_19900 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BtSCAC15_19905 ENOG4105CK7 Sodium proline symporter BtSCAC15_19910 ENOG4105CBC glutamate synthase BtSCAC15_19915 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BtSCAC15_19920 ENOG4108VJ1 Transcriptional regulator (CarD family BtSCAC15_19925 ENOG4108903 Formimidoylglutamase BtSCAC15_19930 ENOG4105CI2 imidazolone-5-propionate hydrolase BtSCAC15_19935 ENOG4105CGP Urocanate hydratase BtSCAC15_19990 ENOG4107QIV Cytochrome c biogenesis protein BtSCAC15_20005 ENOG4105CH2 amidohydrolase BtSCAC15_20015 ENOG4105CJ1 ABC, transporter BtSCAC15_20030 ENOG4107RSM transcriptional regulator BtSCAC15_20035 ENOG4105VAW lrga family BtSCAC15_20040 ENOG41067MG lrgb family BtSCAC15_20080 ENOG4105BZ1 (ABC) transporter BtSCAC15_20085 ENOG4105BZ1 (ABC) transporter BtSCAC15_20120 ENOG4108HW3 (ABC) transporter BtSCAC15_20125 ENOG4105CGH 5'-nucleotidase BtSCAC15_20135 ENOG4108SVB resolvase BtSCAC15_20155 ENOG4105K7K Transcriptional regulator BtSCAC15_20160 ENOG4105C5F glutamine synthetase BtSCAC15_20165 ENOG4105KV4 Transcriptional regulator BtSCAC15_20170 ENOG4105CXI aluminum resistance protein BtSCAC15_20175 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BtSCAC15_20180 ENOG4105EN6 Membrane BtSCAC15_20185 ENOG4106F1P AAA ATPase, central domain protein BtSCAC15_20215 ENOG41069ER domain protein BtSCAC15_20225 ENOG4105DM4 PTS System BtSCAC15_20230 ENOG4105DE4 1-phosphofructokinase BtSCAC15_20235 ENOG4105E98 transcriptional regulator DeoR family BtSCAC15_20240 ENOG4107QW4 alcohol dehydrogenase BtSCAC15_20245 ENOG4108SJC Membrane BtSCAC15_20260 ENOG4105C85 amino acid BtSCAC15_20280 ENOG4105TMB Formate nitrite transporter BtSCAC15_20285 ENOG4105K70 DNA-binding protein BtSCAC15_20295 ENOG4105C59 p-type ATPase BtSCAC15_20300 ENOG410681U heavy metal transport detoxification protein BtSCAC15_20305 ENOG4105VPX protein, conserved in bacteria BtSCAC15_20315 ENOG4105NIV Esterase BtSCAC15_20320 ENOG4105E0A ABC, transporter BtSCAC15_20345 ENOG4105CGK Exodeoxyribonuclease III BtSCAC15_20355 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BtSCAC15_20360 ENOG4105D03 DNA-3-methyladenine glycosylase II BtSCAC15_20365 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BtSCAC15_20395 ENOG4105BZU Histidine kinase BtSCAC15_20435 ENOG41067MG lrgb family BtSCAC15_20455 ENOG4108S3Y transcriptional regulator BtSCAC15_20460 ENOG4105CS2 ec 3.2.1.21 BtSCAC15_20475 ENOG4105F0V Cell wall hydrolase BtSCAC15_20490 ENOG4105E0M Sulfatase BtSCAC15_20495 ENOG410890F Dynamin family BtSCAC15_20525 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BtSCAC15_20530 ENOG4105DQU oxidoreductase, subunit beta BtSCAC15_20535 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BtSCAC15_20540 ENOG4108IGT Dipeptidase BtSCAC15_20545 ENOG4105MCT stage V sporulation protein S BtSCAC15_20550 ENOG4105D48 metallophosphoesterase BtSCAC15_20565 ENOG4105CEV competence damage-inducible protein BtSCAC15_20570 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BtSCAC15_20585 ENOG4105XZV Protein of unknown function (DUF3243) BtSCAC15_20590 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BtSCAC15_20610 ENOG4105UIB (ABC) transporter BtSCAC15_20615 ENOG4108JQ9 ABC transporter BtSCAC15_20620 ENOG4105DIH basic membrane BtSCAC15_20625 ENOG4105FDP GntR family transcriptional regulator BtSCAC15_20635 ENOG4105CNU cell division protein FtsK BtSCAC15_20645 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BtSCAC15_20655 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BtSCAC15_20665 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BtSCAC15_20670 ENOG4108S0H Dipicolinic acid synthetase, b subunit BtSCAC15_20675 ENOG4105E35 Dipicolinate synthase subunit A BtSCAC15_20685 ENOG4105C1V Peptidase, M16 BtSCAC15_20705 ENOG4105DTN riboflavin biosynthesis protein ribF BtSCAC15_20720 ENOG4105W7A Protein of unknown function (DUF503) BtSCAC15_20730 ENOG4105VHM ribosomal protein BtSCAC15_20735 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BtSCAC15_20740 ENOG4105CHV Transcription elongation factor NusA BtSCAC15_20750 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BtSCAC15_20760 ENOG4105DZP Membrane-associated zinc metalloprotease BtSCAC15_20765 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BtSCAC15_20770 ENOG4105KNE Phosphatidate cytidylyltransferase BtSCAC15_20775 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BtSCAC15_20785 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BtSCAC15_20815 ENOG4108HE4 integrase family BtSCAC15_20820 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) BtSCAC15_20825 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BtSCAC15_20830 ENOG4105C79 DNA protecting protein DprA BtSCAC15_20835 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BtSCAC15_20850 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BtSCAC15_20875 ENOG4105VB6 UPF0109 protein BtSCAC15_20895 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BtSCAC15_20900 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BtSCAC15_20915 ENOG4105CHR reductase BtSCAC15_20920 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BtSCAC15_20935 ENOG4105CB5 ATP-dependent DNA helicase recG BtSCAC15_20940 ENOG4105DP4 dak2 domain fusion protein ylov BtSCAC15_20945 ENOG4108ZAA Alkaline-shock protein BtSCAC15_20960 ENOG4105FJ0 thiamine BtSCAC15_20965 ENOG4105DJV ribulose-phosphate 3-epimerase BtSCAC15_20970 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BtSCAC15_20975 ENOG4105D9P serine threonine protein kinase BtSCAC15_20980 ENOG4108ZF3 Phosphatase BtSCAC15_20985 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BtSCAC15_20990 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BtSCAC15_21005 ENOG4105C25 Primosomal protein n' BtSCAC15_21010 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BtSCAC15_21030 ENOG4105DSJ YicC domain protein BtSCAC15_21040 ENOG4105F23 Fibronectin-binding protein BtSCAC15_21045 ENOG4105DC7 peptidase M24 BtSCAC15_21070 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BtSCAC15_21085 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) BtSCAC15_21090 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BtSCAC15_21100 ENOG4105CD3 dihydroorotase BtSCAC15_21120 ENOG4105C34 Pseudouridine synthase BtSCAC15_21135 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BtSCAC15_21145 ENOG4105DBK s4 domain protein BtSCAC15_21150 ENOG41067XK integral membrane protein BtSCAC15_21160 ENOG4105DFA alanine racemase domain protein BtSCAC15_21165 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BtSCAC15_21170 ENOG4105WR5 sporulation protein, YlmC YmxH family BtSCAC15_21185 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BtSCAC15_21195 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BtSCAC15_21200 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BtSCAC15_21210 ENOG4105D4A Cell wall formation (By similarity) BtSCAC15_21215 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BtSCAC15_21220 ENOG4105CNI cell division protein FtsW BtSCAC15_21225 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BtSCAC15_21235 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BtSCAC15_21240 ENOG4105CJN penicillin-binding protein BtSCAC15_21245 ENOG4105CJN penicillin-binding protein BtSCAC15_21260 ENOG41074B2 UPF0747 protein BtSCAC15_21285 ENOG4105KNH Nucleic acid-binding protein BtSCAC15_21295 ENOG41063PX domain protein BtSCAC15_21300 ENOG4105D78 K07001 NTE family protein BtSCAC15_21305 ENOG4105H20 Sporulation integral membrane protein YlbJ BtSCAC15_21315 ENOG4106H78 methyltransferase BtSCAC15_21335 ENOG4107TB6 phosphoglycerate mutase BtSCAC15_21350 ENOG4106UY4 Inherit from COG: Scp-like extracellular BtSCAC15_21395 ENOG4107VFP cytochrome oxidase assembly BtSCAC15_21400 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BtSCAC15_21410 ENOG4105CNI cell division protein FtsW BtSCAC15_21425 ENOG4108IAB Phoh family BtSCAC15_21445 ENOG4105QA2 BtSCAC15_21450 ENOG4105CI3 gtp-binding protein typa BtSCAC15_21460 ENOG4105ECY inositol monophosphatase BtSCAC15_21480 ENOG4105CXN decarboxylase BtSCAC15_21530 ENOG4105CPP Dehydrogenase, E1 component BtSCAC15_21545 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BtSCAC15_21550 ENOG4108X4Q Hydrolase BtSCAC15_21565 ENOG4105CN5 Metallo-Beta-Lactamase BtSCAC15_21570 ENOG4107ZYR domain protein BtSCAC15_21605 ENOG4108XRC Protein of unknown function (DUF458) BtSCAC15_21615 ENOG4107IN1 Protein of unknown function (DUF1797) BtSCAC15_21635 ENOG4105EPM Diguanylate phosphodiesterase BtSCAC15_21640 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BtSCAC15_21655 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BtSCAC15_21665 ENOG4105UIN BtSCAC15_21700 ENOG4107QYE Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BtSCAC15_21725 ENOG4108HGU Histidine kinase BtSCAC15_21735 ENOG4105CHM Aminotransferase BtSCAC15_21740 ENOG4105FKQ transcriptional regulator BtSCAC15_21745 ENOG4105EG2 ABC transporter, permease BtSCAC15_21755 ENOG4107FKK extracellular solute-binding protein family 1 BtSCAC15_21765 ENOG4105CG3 alpha amylase, catalytic region BtSCAC15_21815 ENOG4105CHU acetyl-coa acetyltransferase BtSCAC15_21850 ENOG4105K7K Transcriptional regulator BtSCAC15_21855 ENOG4105DTD Dehydrogenase BtSCAC15_21875 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BtSCAC15_21885 ENOG4105DT1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate BtSCAC15_21900 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BtSCAC15_21915 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BtSCAC15_21925 ENOG4105BZU Histidine kinase BtSCAC15_21945 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BtSCAC15_21960 ENOG4105CID antiterminator BtSCAC15_21970 ENOG4105FDP GntR family transcriptional regulator BtSCAC15_21980 ENOG4105CE4 GlcNAc 6-P deacetylase BtSCAC15_22020 ENOG4107ZE5 PPIases accelerate the folding of proteins BtSCAC15_22025 ENOG4105PTM secreted protein BtSCAC15_22030 ENOG4105J7I hydrolase BtSCAC15_22040 ENOG4105G6R Stage v sporulation protein ae BtSCAC15_22050 ENOG4105CZ3 stage V sporulation protein ad BtSCAC15_22055 ENOG41090VF Stage v sporulation protein ac BtSCAC15_22075 ENOG4105C8J )-transporter BtSCAC15_22080 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BtSCAC15_22090 ENOG41082AN stage II sporulation protein BtSCAC15_22095 ENOG4105DZ1 carboxypeptidase BtSCAC15_22105 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BtSCAC15_22110 ENOG4105DVE abc transporter atp-binding protein BtSCAC15_22175 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BtSCAC15_22185 ENOG4105I3K Ferric uptake regulator, Fur family BtSCAC15_22190 ENOG4105MZ9 stage II sporulation protein m BtSCAC15_22210 ENOG4105CPC Aldo Keto reductase BtSCAC15_22220 ENOG4105RHY Pfam:UPF0157 BtSCAC15_22240 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BtSCAC15_22250 ENOG4105ETE Transcriptional regulator (LacI family BtSCAC15_22255 ENOG4108YM7 Gcn5-related n-acetyltransferase BtSCAC15_22275 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BtSCAC15_22280 ENOG4108R6K riboflavin synthase, subunit alpha BtSCAC15_22310 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BtSCAC15_22315 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BtSCAC15_22325 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BtSCAC15_22330 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BtSCAC15_22345 ENOG4105DFD Na H antiporter BtSCAC15_22350 ENOG4105CGH 5'-nucleotidase BtSCAC15_22375 ENOG4105DBV ornithine carbamoyltransferase BtSCAC15_22390 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BtSCAC15_22405 ENOG4108IXY short-chain dehydrogenase reductase BtSCAC15_22410 ENOG41069FQ Metallo-beta-lactamase superfamily BtSCAC15_22415 ENOG4105II7 pyrroline-5-carboxylate reductase BtSCAC15_22420 ENOG4105EJQ L-serine dehydratase BtSCAC15_22440 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BtSCAC15_22455 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BtSCAC15_22470 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BtSCAC15_22475 ENOG4105D9U N-acetyltransferase BtSCAC15_22495 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BtSCAC15_22500 ENOG4108QEG Membrane BtSCAC15_22505 ENOG4105CDA abc transporter atp-binding protein BtSCAC15_22510 ENOG4105E5Q amino acid AbC transporter BtSCAC15_22515 ENOG4108HW3 (ABC) transporter BtSCAC15_22525 ENOG4105G7B Protein of unknown function (DUF2992) BtSCAC15_22535 ENOG4108QY0 Membrane BtSCAC15_22550 ENOG4105C7S Dehydrogenase BtSCAC15_22555 ENOG4105CPP Dehydrogenase, E1 component BtSCAC15_22570 ENOG4105CKM Branched-chain carboxylic acid kinase BtSCAC15_22575 ENOG4107RDP Dehydrogenase BtSCAC15_22590 ENOG4108JUB Transcriptional regulator BtSCAC15_22600 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BtSCAC15_22615 ENOG4107QQR Sporulation BtSCAC15_22625 ENOG4105S1Z Stage IV sporulation protein B BtSCAC15_22630 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BtSCAC15_22635 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BtSCAC15_22640 ENOG4105DX0 Hemolysin A BtSCAC15_22650 ENOG4105CTB Polyprenyl synthetase BtSCAC15_22665 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BtSCAC15_22675 ENOG4108ZSR alkaline shock protein BtSCAC15_22680 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BtSCAC15_22705 ENOG410644B Stage III sporulation protein af BtSCAC15_22715 ENOG4105KQ4 Stage iii sporulation protein ad BtSCAC15_22720 ENOG4108CQH stage III sporulation protein AC BtSCAC15_22725 ENOG4105KR5 Stage iii sporulation protein BtSCAC15_22730 ENOG4105CD2 stage iii sporulation protein aa BtSCAC15_22755 ENOG4105DC7 peptidase M24 BtSCAC15_22760 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BtSCAC15_22770 ENOG4105CBJ Metal-dependent enzyme BtSCAC15_22780 ENOG4107YBY Hydrolase BtSCAC15_22810 ENOG41082GG biotin lipoate A B protein ligase BtSCAC15_22815 ENOG4105WZW rhodanese family BtSCAC15_22840 ENOG41080TC multidrug resistance protein BtSCAC15_22875 ENOG4105CJ1 ABC, transporter BtSCAC15_22880 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BtSCAC15_22895 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BtSCAC15_22915 ENOG4105C0D helicase BtSCAC15_23170 ENOG4107R6U sodium dicarboxylate symporter BtSCAC15_23205 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BtSCAC15_23210 ENOG4105C3R Methionine synthase BtSCAC15_23220 ENOG4105C28 cystathionine BtSCAC15_23225 ENOG4105C28 cystathionine BtSCAC15_23245 ENOG4105C5X domain protein BtSCAC15_23255 ENOG4105DKQ ROK family BtSCAC15_23265 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BtSCAC15_23280 ENOG4108UTW Plays a role in the regulation of phosphate uptake BtSCAC15_23285 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BtSCAC15_23290 ENOG4105C8U phosphate abc transporter BtSCAC15_23295 ENOG4105C8U phosphate abc transporter BtSCAC15_23300 ENOG4105EXS phosphate abc transporter BtSCAC15_23305 ENOG4107RF6 penicillin-binding protein BtSCAC15_23315 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BtSCAC15_23340 ENOG4105N80 Ferric uptake regulator, Fur family BtSCAC15_23350 ENOG4105FDK ABC transporter BtSCAC15_23355 ENOG4108JYZ YitT family BtSCAC15_23360 ENOG41069ZM Protein of unknown function (DUF2624) BtSCAC15_23385 ENOG4105EGD dinuclear metal center protein, YbgI family BtSCAC15_23400 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BtSCAC15_23405 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BtSCAC15_23440 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BtSCAC15_23445 ENOG4105KG3 cytidine deaminase BtSCAC15_23450 ENOG4107YR5 Diacylglycerol kinase BtSCAC15_23455 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BtSCAC15_23460 ENOG4105CTJ Metal Dependent Phosphohydrolase BtSCAC15_23465 ENOG4105C9A Phoh family BtSCAC15_23475 ENOG41068P3 sporulation protein YqfC BtSCAC15_23485 ENOG4105KTH gatB Yqey BtSCAC15_23500 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BtSCAC15_23505 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BtSCAC15_23535 ENOG4105CSA Coproporphyrinogen iii oxidase BtSCAC15_23540 ENOG4105KVH Transcriptional regulator BtSCAC15_23565 ENOG4105TQK DNA polymerase iii, delta' subunit BtSCAC15_23575 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BtSCAC15_23580 ENOG4108UK2 deaminase BtSCAC15_23585 ENOG4105KQC Competence protein BtSCAC15_23595 ENOG4105DXX methyltransferase BtSCAC15_23605 ENOG4108WF2 Metal Dependent Phosphohydrolase BtSCAC15_23615 ENOG410812S Rna-binding protein BtSCAC15_23625 ENOG4105CQW ribosome biogenesis GTPase YqeH BtSCAC15_23630 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BtSCAC15_23645 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BtSCAC15_23670 ENOG4108TVJ Nitroreductase BtSCAC15_23685 ENOG4105G6Z alkaline phosphatase BtSCAC15_23690 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BtSCAC15_23695 ENOG4108MUZ hydrolase BtSCAC15_23730 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BtSCAC15_23735 ENOG4105MIR Phenylalanine 4-monooxygenase BtSCAC15_23745 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BtSCAC15_23785 ENOG4105S6R Iron-hydroxamate transporter permease subunit BtSCAC15_23790 ENOG4108V5C ABC transporter BtSCAC15_23805 ENOG4108EKI Dehydrogenase BtSCAC15_23810 ENOG4105C28 cystathionine BtSCAC15_23840 ENOG4107XRG penicillin-binding protein BtSCAC15_23850 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BtSCAC15_23860 ENOG4105CFP Peptidase U32 BtSCAC15_23865 ENOG4105XYU peptidase (U32 family) BtSCAC15_23870 ENOG4108VQJ O-methyltransferase BtSCAC15_23875 ENOG4105HHA aminodeoxychorismate lyase BtSCAC15_23895 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BtSCAC15_23905 ENOG4105C02 permease BtSCAC15_23920 ENOG41060CR BtSCAC15_23925 ENOG4105C7H Helicase, RecD TraA family BtSCAC15_23935 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BtSCAC15_23940 ENOG4105C3J Cysteine desulfurase BtSCAC15_23950 ENOG4105D1H recombination factor protein RarA BtSCAC15_23955 ENOG4108VCI transcription factor, rsfa family BtSCAC15_23970 ENOG4105CUZ uba thif-type nad fad binding protein BtSCAC15_23980 ENOG4105CUT histidyl-tRNA synthetase BtSCAC15_23990 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BtSCAC15_23995 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BtSCAC15_24005 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BtSCAC15_24010 ENOG41076HS cation diffusion facilitator family transporter BtSCAC15_24015 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BtSCAC15_24025 ENOG4105CKP Polysaccharide Biosynthesis Protein BtSCAC15_24030 ENOG4108QG2 Membrane BtSCAC15_24040 ENOG4105VIE preprotein translocase, subunit YajC BtSCAC15_24055 ENOG41061AI Protein of unknown function (DUF2905) BtSCAC15_24070 ENOG4108HUF Transporter BtSCAC15_24095 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BtSCAC15_24100 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BtSCAC15_24105 ENOG4108IYU L-aspartate oxidase BtSCAC15_24120 ENOG4108RPX mosc domain containing protein BtSCAC15_24125 ENOG4105CQC Prephenate dehydratase BtSCAC15_24140 ENOG4105C19 ABC transporter BtSCAC15_24145 ENOG4105EWM Histidine kinase BtSCAC15_24155 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BtSCAC15_24170 ENOG4105X36 (ribosomal) protein BtSCAC15_24180 ENOG4105C03 ribonuclease BtSCAC15_24195 ENOG4107QMS site-determining protein BtSCAC15_24210 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BtSCAC15_24215 ENOG4105DFF Rod shape-determining protein mreb BtSCAC15_24310 ENOG4107Y5K Resolvase BtSCAC15_24320 ENOG4108Z03 MAF-like protein BtSCAC15_24330 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BtSCAC15_24335 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BtSCAC15_24345 ENOG41068KH stage VI sporulation protein D BtSCAC15_24355 ENOG4105D52 delta-aminolevulinic acid dehydratase BtSCAC15_24380 ENOG4105K56 Transcriptional regulator BtSCAC15_24400 ENOG4108IUQ atp-dependent protease BtSCAC15_24425 ENOG4108QCI YvbH-like oligomerisation region BtSCAC15_24450 ENOG4105M59 Phosphodiesterase, mj0936 family BtSCAC15_24455 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BtSCAC15_24465 ENOG4108XJQ germination protein BtSCAC15_24475 ENOG4108PCX Major Facilitator BtSCAC15_24490 ENOG4105KBX Transcriptional regulator, TetR family BtSCAC15_24500 ENOG4105PFC Transcriptional regulator BtSCAC15_24510 ENOG4105DZC cytosine deaminase BtSCAC15_24515 ENOG41067S9 phage shock protein C, PspC BtSCAC15_24520 ENOG4108JCI Transcriptional regulator BtSCAC15_24530 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BtSCAC15_24535 ENOG4108Z40 Transcriptional regulator BtSCAC15_24540 ENOG4105RHA ABC transporter, permease BtSCAC15_24545 ENOG4108IUX (ABC) transporter BtSCAC15_24550 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BtSCAC15_24555 ENOG4105ER2 Ompa motb domain protein BtSCAC15_24560 ENOG4105E14 MotA TolQ exbB proton channel BtSCAC15_24570 ENOG4108VXD carboxy-peptidase BtSCAC15_24580 ENOG4105E33 succinate dehydrogenase BtSCAC15_24590 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BtSCAC15_24600 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BtSCAC15_24605 ENOG4105K63 Thioredoxin BtSCAC15_24610 ENOG4105C10 Electron transfer flavoprotein BtSCAC15_24615 ENOG4105BZJ Electron transfer flavoprotein BtSCAC15_24620 ENOG41060WC Enoyl-CoA hydratase BtSCAC15_24625 ENOG4107Z3H Transcriptional regulator, TetR family BtSCAC15_24630 ENOG4105CEY Amp-dependent synthetase and ligase BtSCAC15_24645 ENOG4105J76 Periplasmic binding protein BtSCAC15_24660 ENOG4105S6R Iron-hydroxamate transporter permease subunit BtSCAC15_24710 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BtSCAC15_24725 ENOG4105DR4 Methyltransferase BtSCAC15_24740 ENOG4105KFN sortase, SrtB family BtSCAC15_24745 ENOG4105E0A ABC, transporter BtSCAC15_24760 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BtSCAC15_24770 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BtSCAC15_24780 ENOG4105FE9 pseudouridine synthase BtSCAC15_24795 ENOG4105DCG PHP domain protein BtSCAC15_24810 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BtSCAC15_24830 ENOG4105C5S asparaginyl-tRNA synthetase BtSCAC15_24835 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BtSCAC15_24845 ENOG4108RWN rrna methyltransferase BtSCAC15_24875 ENOG4105C0R drug resistance transporter emrb qaca subfamily BtSCAC15_24880 ENOG4105CW7 secretion protein, HlyD family BtSCAC15_24890 ENOG4108JGH Tetr family transcriptional regulator BtSCAC15_24895 ENOG4105CN9 Peptidase m42 family protein BtSCAC15_24915 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BtSCAC15_24920 ENOG4105C22 threonyL-tRNA synthetase BtSCAC15_24925 ENOG4108TDW sporulation protein YtxC BtSCAC15_24950 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BtSCAC15_24960 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BtSCAC15_24965 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BtSCAC15_24975 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BtSCAC15_24980 ENOG4105C2M dna polymerase I BtSCAC15_24985 ENOG4105BZU Histidine kinase BtSCAC15_24990 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BtSCAC15_25005 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BtSCAC15_25010 ENOG4108HMX isocitrate dehydrogenase (NADP) BtSCAC15_25015 ENOG4105BZN citrate synthase BtSCAC15_25030 ENOG4108REF Sporulation integral membrane protein ytvi BtSCAC15_25035 ENOG4105FS0 cytoplasmic membrane protein BtSCAC15_25060 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BtSCAC15_25065 ENOG4105C6K Malic enzyme BtSCAC15_25070 ENOG4105C0B DNA polymerase III (alpha subunit) BtSCAC15_25075 ENOG4105VV2 BtSCAC15_25085 ENOG4105SFS phosphoesterase RecJ domain protein BtSCAC15_25110 ENOG4105E8R UPF0173 metal-dependent hydrolase BtSCAC15_25115 ENOG4105DC7 peptidase M24 BtSCAC15_25155 ENOG4105Z7P Acetyltransferase (GNAT) family BtSCAC15_25160 ENOG41082W1 Cupin 2, conserved barrel domain protein BtSCAC15_25180 ENOG4107YZX Universal stress protein BtSCAC15_25225 ENOG4108JYZ YitT family BtSCAC15_25245 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BtSCAC15_25255 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BtSCAC15_25260 ENOG4105KBJ sporulation protein ytfj BtSCAC15_25275 ENOG4105EFZ amidohydrolase BtSCAC15_25285 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BtSCAC15_25310 ENOG4105RQF LysR family Transcriptional regulator BtSCAC15_25320 ENOG4105U5Y Transcriptional regulator BtSCAC15_25330 ENOG4105C28 cystathionine BtSCAC15_25385 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BtSCAC15_25390 ENOG4108UW5 maltose o-acetyltransferase BtSCAC15_25400 ENOG4105F1V Acetoin utilization protein BtSCAC15_25405 ENOG4105W87 Cbs domain BtSCAC15_25410 ENOG4105DGU Histone deacetylase BtSCAC15_25425 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BtSCAC15_25435 ENOG4107SNB ankyrin repeat protein YahD BtSCAC15_25440 ENOG4105EP9 oxidoreductase BtSCAC15_25460 ENOG4105ETE Transcriptional regulator (LacI family BtSCAC15_25475 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BtSCAC15_25495 ENOG4105C88 aminopeptidase BtSCAC15_25540 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BtSCAC15_25550 ENOG4108VDD TRNA binding domain protein BtSCAC15_25580 ENOG4105C8F Beta-lactamase domain protein BtSCAC15_25595 ENOG4108V15 phosphotransferase enzyme family BtSCAC15_25600 ENOG4108IUM Glycogen debranching enzyme BtSCAC15_25615 ENOG4107QSE Dipeptidase BtSCAC15_25620 ENOG4105YW5 deoR family transcriptional regulator BtSCAC15_25635 ENOG4105CBX hi0933 family BtSCAC15_25680 ENOG4108VJ1 Transcriptional regulator (CarD family BtSCAC15_25685 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BtSCAC15_25690 ENOG4105CSC Glucose uptake protein BtSCAC15_25705 ENOG4108ZAF Molybdopterin BtSCAC15_25710 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BtSCAC15_25715 ENOG4105CVM Molybdenum cofactor synthesis domain protein BtSCAC15_25725 ENOG4105D06 uba thif-type nad fad binding protein BtSCAC15_25730 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BtSCAC15_25755 ENOG41085GJ domain protein BtSCAC15_25765 ENOG4105DWV Homoserine O-trans-acetylase BtSCAC15_25775 ENOG4108B31 Spore germination protein BtSCAC15_25800 ENOG4105C8T Leucyl-tRNA synthetase BtSCAC15_25805 ENOG410605W Major Facilitator BtSCAC15_25810 ENOG4107S91 Sodium hydrogen exchanger BtSCAC15_25815 ENOG4105NCW Trka-c domain protein BtSCAC15_25830 ENOG4105C19 ABC transporter BtSCAC15_25850 ENOG4105N5T Radical SAM Protein BtSCAC15_25880 ENOG4105E8V Alpha Beta Hydrolase Fold protein BtSCAC15_25885 ENOG4108Z0R Transferase BtSCAC15_25890 ENOG4105YVM Phosphoesterase, PA-phosphatase related BtSCAC15_25895 ENOG4105BZF Glycosyl transferase (Group 1 BtSCAC15_25905 ENOG4105EPU Molybdenum cofactor synthesis domain protein BtSCAC15_25915 ENOG4108MK9 spermidine N(1)-acetyltransferase BtSCAC15_25975 ENOG4105BZU Histidine kinase BtSCAC15_25980 ENOG4105BZU Histidine kinase BtSCAC15_25985 ENOG4105CH6 catalase BtSCAC15_25995 ENOG4107S9D Alpha beta hydrolase BtSCAC15_26000 ENOG4107T7U Sulfatase BtSCAC15_26015 ENOG4105D2X ABC transporter substrate-binding protein BtSCAC15_26025 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BtSCAC15_26110 ENOG4108V2W Carbonate dehydratase BtSCAC15_26115 ENOG4105C4M (Ubiquinol oxidase) subunit I BtSCAC15_26120 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BtSCAC15_26160 ENOG41087YS Phage shock protein A BtSCAC15_26200 ENOG4105BZU Histidine kinase BtSCAC15_26205 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_26280 ENOG4105C19 ABC transporter BtSCAC15_26370 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_26390 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BtSCAC15_26840 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BtSCAC15_26880 ENOG4105KT7 mgtC SapB transporter BtSCAC15_26885 ENOG4107PBV potassium channel BtSCAC15_26905 ENOG4105WG9 Conserved Protein BtSCAC15_26915 ENOG4105CHM Aminotransferase BtSCAC15_26920 ENOG4108ZB6 transcriptional regulator AsnC family BtSCAC15_26925 ENOG4105C5I Dehydrogenase BtSCAC15_26930 ENOG4108MUZ hydrolase BtSCAC15_26940 ENOG4105C87 Aminotransferase class I and II BtSCAC15_26955 ENOG4105Y38 Kinase-associated protein B BtSCAC15_26965 ENOG4107R3E Citrate transporter BtSCAC15_26995 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BtSCAC15_27000 ENOG4105KA0 thioesterase Superfamily protein BtSCAC15_27015 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BtSCAC15_27040 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) BtSCAC15_27045 ENOG4106YN8 Prenyltransferase BtSCAC15_27050 ENOG41069ER domain protein BtSCAC15_27065 ENOG4105CEP NADH dehydrogenase BtSCAC15_27095 ENOG4105EWC Purine nucleoside phosphorylase BtSCAC15_27110 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BtSCAC15_27135 ENOG4108JJA ABC, transporter BtSCAC15_27140 ENOG4105C4B ABC transporter, permease BtSCAC15_27145 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BtSCAC15_27175 ENOG41083MR nifu domain-containing protein BtSCAC15_27195 ENOG4108W5N phosphatidylglycerophosphatase a BtSCAC15_27215 ENOG4105DAX Pfam:DUF2983 BtSCAC15_27235 ENOG4105DYS nad(p)h dehydrogenase (quinone) BtSCAC15_27240 ENOG4105D4U had-superfamily hydrolase, subfamily iia BtSCAC15_27255 ENOG4105CBT Fructose-1,6-bisphosphatase BtSCAC15_27275 ENOG4105MMD transcriptional regulator BtSCAC15_27280 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BtSCAC15_27285 ENOG4107TXC Transcriptional regulator BtSCAC15_27290 ENOG41090T1 Membrane BtSCAC15_27315 ENOG4105FAA peptidase M23 BtSCAC15_27320 ENOG4108YTE sporulation protein YunB BtSCAC15_27325 ENOG4105KZD Domain of unknown function (DUF1805) BtSCAC15_27330 ENOG4107R8B 5'-nucleotidase BtSCAC15_27335 ENOG4105DIW FeS assembly protein SUFB BtSCAC15_27340 ENOG4108UNV SUF system FeS assembly protein, NifU family BtSCAC15_27345 ENOG4105C9B Cysteine desulfurase BtSCAC15_27350 ENOG4105JRK feS assembly protein SufD BtSCAC15_27355 ENOG4105C3K feS assembly ATPase SufC BtSCAC15_27360 ENOG4105D01 (LipO)protein BtSCAC15_27365 ENOG4105D01 (LipO)protein BtSCAC15_27370 ENOG4108UMI ABC transporter, permease BtSCAC15_27410 ENOG41080E8 Transcriptional regulator, Spx MgsR family BtSCAC15_27430 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BtSCAC15_27460 ENOG4108W8B Beta-lactamase domain protein BtSCAC15_27465 ENOG4105C1G acyl-Coa dehydrogenase BtSCAC15_27470 ENOG4105CHU acetyl-coa acetyltransferase BtSCAC15_27490 ENOG4105DZ1 carboxypeptidase BtSCAC15_27530 ENOG4108SUT Major Facilitator Superfamily BtSCAC15_27535 ENOG4107R7I amino acid BtSCAC15_27550 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BtSCAC15_27560 ENOG4107AYK membrAne BtSCAC15_27610 ENOG4107ZTW SNARE associated Golgi BtSCAC15_27620 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BtSCAC15_27625 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_27630 ENOG4105BZU Histidine kinase BtSCAC15_27645 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BtSCAC15_27660 ENOG4105C8Q Methyl-accepting chemotaxis BtSCAC15_27665 ENOG4105VG1 fes assembly suf system protein BtSCAC15_27670 ENOG4105D4Y metalloprotease BtSCAC15_27690 ENOG4107T5V SNARE associated Golgi BtSCAC15_27695 ENOG4107S91 Sodium hydrogen exchanger BtSCAC15_27700 ENOG4105NCW Trka-c domain protein BtSCAC15_27720 ENOG4108RMU ferritin dps family protein BtSCAC15_27735 ENOG4108URH decarboxylase BtSCAC15_27745 ENOG41090A1 ferritin BtSCAC15_27755 ENOG4105D9N nucleoside BtSCAC15_27760 ENOG4105D9N nucleoside BtSCAC15_27775 ENOG4108RYK Nad-dependent epimerase dehydratase BtSCAC15_27795 ENOG4105CV8 reductase BtSCAC15_27800 ENOG4105F27 Major Facilitator BtSCAC15_27805 ENOG4105KVH Transcriptional regulator BtSCAC15_27820 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BtSCAC15_27825 ENOG4105D4A Cell wall formation (By similarity) BtSCAC15_27845 ENOG4105WMR Protein CrcB homolog BtSCAC15_27850 ENOG4105WMR Protein CrcB homolog BtSCAC15_27870 ENOG4105C5H ABC transporter BtSCAC15_27875 ENOG4108MK9 spermidine N(1)-acetyltransferase BtSCAC15_27880 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BtSCAC15_27910 ENOG4108IPW abc transporter atp-binding protein BtSCAC15_27915 ENOG4105CM4 permease protein BtSCAC15_27950 ENOG4105DQ6 Transposase BtSCAC15_27980 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BtSCAC15_28120 ENOG4105WXW Antirepressor BtSCAC15_28140 ENOG4105F5W AtP-binding protein BtSCAC15_28185 ENOG4105XZU Preprotein translocase, subunit SecG BtSCAC15_28190 ENOG41067MG lrgb family BtSCAC15_28210 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BtSCAC15_28240 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BtSCAC15_28260 ENOG41090VF Stage v sporulation protein ac BtSCAC15_28265 ENOG4105CZ3 stage V sporulation protein ad BtSCAC15_28280 ENOG4108QY0 Membrane BtSCAC15_28285 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BtSCAC15_28290 ENOG4105KRI phosphocarrier protein (HPr BtSCAC15_28300 ENOG4105CHW UPF0052 protein BtSCAC15_28305 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BtSCAC15_28310 ENOG4108Z4K mutator MutT protein BtSCAC15_28320 ENOG4105C3M thioredoxin reductase BtSCAC15_28330 ENOG4108S4C acetyltransferase BtSCAC15_28340 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) BtSCAC15_28350 ENOG41086DT Membrane protein of unknown function BtSCAC15_28360 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BtSCAC15_28380 ENOG4107TXC Transcriptional regulator BtSCAC15_28400 ENOG4105DUM transcriptional regulator, lysR family BtSCAC15_28410 ENOG4108WS4 fmn reductase BtSCAC15_28425 ENOG4105BZ1 (ABC) transporter BtSCAC15_28440 ENOG4105CN1 protease BtSCAC15_28445 ENOG4105CRP Part of the ABC transporter FtsEX involved in BtSCAC15_28450 ENOG4105CAK Cell division ATP-binding protein ftsE BtSCAC15_28470 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BtSCAC15_28485 ENOG4105MS2 ribosomal subunit Interface protein BtSCAC15_28490 ENOG4105VEQ Cold shock protein BtSCAC15_28495 ENOG41081UC Inherit from COG: Competence protein BtSCAC15_28510 ENOG4105KVH Transcriptional regulator BtSCAC15_28525 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BtSCAC15_28530 ENOG4108KGH TRANSCRIPTIONal BtSCAC15_28535 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BtSCAC15_28540 ENOG4105C6Y Udp-glucose 6-dehydrogenase BtSCAC15_28545 ENOG4105ESV Glycosyl transferase, family 4 BtSCAC15_28555 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BtSCAC15_28585 ENOG4105F8D glycoside hydrolase family 4 BtSCAC15_28590 ENOG4105VCP PTS System BtSCAC15_28595 ENOG4105CK1 PTS System BtSCAC15_28605 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BtSCAC15_28610 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BtSCAC15_28615 ENOG4105VCP PTS System BtSCAC15_28625 ENOG4105VZJ PTS System BtSCAC15_28645 ENOG4105ECB domain protein BtSCAC15_28650 ENOG4107RSM transcriptional regulator BtSCAC15_28705 ENOG4105DAA L-lactate BtSCAC15_28715 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BtSCAC15_28730 ENOG4105E0M Sulfatase BtSCAC15_28760 ENOG4107R8N Glycosyl transferase, family 2 BtSCAC15_28770 ENOG4105C94 Transporter BtSCAC15_28780 ENOG41069ER domain protein BtSCAC15_28805 ENOG4105KBK Zinc finger, swim domain protein BtSCAC15_28810 ENOG4105C0D helicase BtSCAC15_28840 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BtSCAC15_28850 ENOG4107RBB ABC transporter, permease BtSCAC15_28855 ENOG4105C19 ABC transporter BtSCAC15_28865 ENOG4105CXY transporter BtSCAC15_28880 ENOG4105BZU Histidine kinase BtSCAC15_28885 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_28895 ENOG4108KGH TRANSCRIPTIONal BtSCAC15_28900 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BtSCAC15_28910 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BtSCAC15_28925 ENOG4107YJ4 chain length determinant protein BtSCAC15_28930 ENOG4105HTX biosynthesis protein BtSCAC15_28950 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BtSCAC15_28960 ENOG4105FRN stage II sporulation protein BtSCAC15_28975 ENOG4105DY9 regulatoR BtSCAC15_28995 ENOG4106778 Protein of unknown function (DUF1146) BtSCAC15_29000 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BtSCAC15_29005 ENOG4105C8S subunit m BtSCAC15_29010 ENOG4105D65 subunit l BtSCAC15_29035 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BtSCAC15_29040 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BtSCAC15_29050 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BtSCAC15_29055 ENOG4105BZU Histidine kinase BtSCAC15_29105 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BtSCAC15_29110 ENOG41062M3 atp synthase BtSCAC15_29135 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BtSCAC15_29140 ENOG4108UIC UPF0340 protein BtSCAC15_29145 ENOG4108YZG isomerase BtSCAC15_29165 ENOG4108VGI doxx family BtSCAC15_29170 ENOG4107XC4 flavin reductase domain protein, FMN-binding BtSCAC15_29190 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BtSCAC15_29200 ENOG4108ZXQ stage ii sporulation protein r BtSCAC15_29205 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BtSCAC15_29210 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BtSCAC15_29220 ENOG4107104 thymidine kinase BtSCAC15_29230 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BtSCAC15_29235 ENOG4105CBT Fructose-1,6-bisphosphatase BtSCAC15_29245 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BtSCAC15_29265 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BtSCAC15_29280 ENOG4105C1G acyl-Coa dehydrogenase BtSCAC15_29285 ENOG4105C1G acyl-Coa dehydrogenase BtSCAC15_29290 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BtSCAC15_29300 ENOG4105DF6 Fe-S oxidoreductase BtSCAC15_29315 ENOG4105BZU Histidine kinase BtSCAC15_29330 ENOG4105D4Y metalloprotease BtSCAC15_29340 ENOG4105BZU Histidine kinase BtSCAC15_29345 ENOG4105KCT ABC transporter BtSCAC15_29350 ENOG4108M15 ABC transporter BtSCAC15_29355 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BtSCAC15_29385 ENOG4105IIU Aminopeptidase BtSCAC15_29405 ENOG4105DU6 RNA polymerase BtSCAC15_29420 ENOG410684U Domain of unknown function (DUF1934) BtSCAC15_29455 ENOG4105CYW agmatinase BtSCAC15_29465 ENOG4105DXB Major Facilitator superfamily BtSCAC15_29470 ENOG4107SWG transcriptional regulator MERR family BtSCAC15_29475 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BtSCAC15_29480 ENOG4105BZ4 penicillin-binding protein BtSCAC15_29485 ENOG4108XFG YwhD family BtSCAC15_29490 ENOG4108Z4T Peptidase M50 BtSCAC15_29495 ENOG41069HH 4-oxalocrotonate tautomerase BtSCAC15_29500 ENOG4105DCI Phosphohydrolase BtSCAC15_29505 ENOG4108MES Periplasmic binding protein BtSCAC15_29510 ENOG4105E0A ABC, transporter BtSCAC15_29515 ENOG4105EHG Permease protein BtSCAC15_29520 ENOG4105DQ5 transport system permease protein BtSCAC15_29530 ENOG4108VCI transcription factor, rsfa family BtSCAC15_29535 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BtSCAC15_29540 ENOG4108IJ2 phosphate acetyltransferase BtSCAC15_29545 ENOG4107UEZ chlorite dismutase BtSCAC15_29555 ENOG4108VKI Cell wall hydrolase BtSCAC15_29575 ENOG4107SVH Potassium channel protein BtSCAC15_29585 ENOG410667J hydrolase BtSCAC15_29590 ENOG4105VCH membrane BtSCAC15_29600 ENOG4108TU7 Inherit from COG: (ABC) transporter BtSCAC15_29605 ENOG4105CJ1 ABC, transporter BtSCAC15_29610 ENOG41090WU lipolytic protein G-D-S-L family BtSCAC15_29625 ENOG4105D6E homoserine dehydrogenase BtSCAC15_29630 ENOG4105CVG Homoserine O-transsuccinylase BtSCAC15_29660 ENOG4105WH1 Two component transcriptional regulator luxr family BtSCAC15_29665 ENOG4105BZU Histidine kinase BtSCAC15_29670 ENOG4105DWF phosphomethylpyrimidine kinase BtSCAC15_29675 ENOG4105BZU Histidine kinase BtSCAC15_29680 ENOG4105VCD cytoplasmic protein BtSCAC15_29685 ENOG4105D22 carbon starvation protein BtSCAC15_29690 ENOG4105DY9 regulatoR BtSCAC15_29695 ENOG41079KZ Major Facilitator Superfamily BtSCAC15_29710 ENOG4105CG5 Glycosyl transferase (Group 1 BtSCAC15_29720 ENOG4105EN6 Membrane BtSCAC15_29725 ENOG4106YBV Methyl-accepting chemotaxis BtSCAC15_29735 ENOG4108S4H thioesterase Superfamily protein BtSCAC15_29775 ENOG4105K64 Glycosyl transferase, family 2 BtSCAC15_29790 ENOG4105CKK Glycosyl transferase, family 2 BtSCAC15_29795 ENOG4105C5H ABC transporter BtSCAC15_29800 ENOG41067SE Tetr family transcriptional regulator BtSCAC15_29810 ENOG4105E0X reductase BtSCAC15_29815 ENOG4106F5Q Membrane BtSCAC15_29830 ENOG4108NEV two component transcriptional regulator, LytTR family BtSCAC15_29840 ENOG4107RGD Major Facilitator superfamily BtSCAC15_29860 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BtSCAC15_29880 ENOG4105IW1 AmiS UreI transporter BtSCAC15_29890 ENOG4105CMR udp-glucose 4-epimerase BtSCAC15_29895 ENOG4108UT2 hemolysin iii BtSCAC15_29905 ENOG4105C1J atp-dependent rna helicase BtSCAC15_29910 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BtSCAC15_29920 ENOG4105DPN Oligoendopeptidase f BtSCAC15_29930 ENOG4105BZU Histidine kinase BtSCAC15_29935 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BtSCAC15_29945 ENOG4105C0H protease BtSCAC15_29950 ENOG4105Q2H domain protein BtSCAC15_29965 ENOG4105BZU Histidine kinase BtSCAC15_29970 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BtSCAC15_29995 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BtSCAC15_30000 ENOG4105CDU Replicative dna helicase BtSCAC15_30010 ENOG4105BZR domain protein BtSCAC15_30015 ENOG4108XMW Membrane BtSCAC15_30025 ENOG4108UUM single-stranded DNA-binding protein BtSCAC15_30035 ENOG4105C3G gtp-binding protein BtSCAC15_30040 ENOG4105VDK protein, conserved in bacteria BtSCAC15_30045 ENOG4105D8X mechanosensitive ion channel BtSCAC15_30050 ENOG4108ZDA Sporulation protein YyaC BtSCAC15_30055 ENOG4105FA0 parb-like partition protein BtSCAC15_30060 ENOG4107QJE Chromosome Partitioning Protein BtSCAC15_30075 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) BtSCAC15_30080 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BtSCAC15_30090 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BtSCAC15_30200 ENOG4105K70 DNA-binding protein BtSCAC15_30205 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BtSCAC15_30210 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_30275 ENOG4105DQ6 Transposase BtSCAC15_30290 ENOG4108IMY Transcriptional regulator BtSCAC15_30400 ENOG41082J7 Rhodanese domain protein BtSCAC15_30460 ENOG4108IJ6 ABC transporter BtSCAC15_30490 ENOG4105C19 ABC transporter BtSCAC15_30495 ENOG4107RBB ABC transporter, permease BtSCAC15_30575 ENOG4105NCW Trka-c domain protein BtSCAC15_30590 ENOG4108C33 Resolvase BtSCAC15_30600 ENOG4105C9U ATP-dependent DNA helicase RecQ BtSCAC15_30615 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_30620 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BtSCAC15_30765 ENOG4105EXC Acyl-transferase BtSCAC15_30790 ENOG4108V2W Carbonate dehydratase BtSCAC15_30795 ENOG4105CHH sulfate transporter BtSCAC15_30920 ENOG4108IMY Transcriptional regulator BtSCAC15_30990 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BtSCAC15_31025 ENOG4108C33 Resolvase BtSCAC15_31035 ENOG4105DQ6 Transposase BtSCAC15_31060 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BtSCAC15_31095 ENOG4108B31 Spore germination protein BtSCAC15_31100 ENOG4108NHD germination protein BtSCAC15_31175 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BtSCAC15_31180 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_31270 ENOG410836F Transposase BtSCAC15_31290 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_31295 ENOG4108UUM single-stranded DNA-binding protein BtSCAC15_31340 ENOG4105K70 DNA-binding protein BtSCAC15_31345 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BtSCAC15_31375 ENOG4105KRN Transcriptional regulator, abrb family BtSCAC15_31395 ENOG4105C19 ABC transporter BtSCAC15_31410 ENOG4105DQ6 Transposase BtSCAC15_31500 ENOG4105DQ6 Transposase BtSCAC15_31540 ENOG4108BUD transposase BtSCAC15_31620 ENOG4106E8G BtSCAC15_31660 ENOG41085W3 Transposase BtSCAC15_31700 ENOG4107QJE Chromosome Partitioning Protein BtSCAC15_31715 ENOG4108C33 Resolvase BtSCAC15_31825 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein BtSCAC15_31845 ENOG4105DQ6 Transposase BtSCAC15_31940 ENOG4105CPQ Dehydrogenase BtSCAC15_31950 ENOG4105C0R drug resistance transporter emrb qaca subfamily BtSCAC15_31955 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BtSCAC15_32075 ENOG4105DQ6 Transposase BtSCAC15_32135 ENOG4107QJE Chromosome Partitioning Protein BtSCAC15_32150 ENOG4105DQ6 Transposase BtSCAC15_32455 ENOG4105CJ1 ABC, transporter