locus-tag	class	description
FOC85_00005	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOC85_00115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC85_00155	COG1192	Involved in chromosome partitioning
FOC85_00210	COG1396	sequence-specific DNA binding
FOC85_00220	COG3617	BRO family, N-terminal domain
FOC85_00250	COG1484	DNA-dependent DNA replication
FOC85_00350	COG0322	excinuclease ABC activity
FOC85_00355	COG3728	DNA packaging
FOC85_00355	COG5484	DNA packaging
FOC85_00365	COG5518	Phage portal protein
FOC85_00370	COG2369	cell adhesion
FOC85_00405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC85_00410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC85_00415	COG4187	Peptidase family M20/M25/M40
FOC85_00420	COG1414	Transcriptional regulator
FOC85_00430	COG1690	Belongs to the RtcB family
FOC85_00435	COG3239	Fatty acid desaturase
FOC85_00450	COG3655	Transcriptional regulator
FOC85_00465	COG4377	Putative membrane peptidase family (DUF2324)
FOC85_00475	COG3279	Response regulator of the LytR AlgR family
FOC85_00485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_00490	COG0346	lactoylglutathione lyase activity
FOC85_00535	COG0463	Glycosyl transferase, family 2
FOC85_00550	COG0463	Glycosyl transferase, family 2
FOC85_00560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC85_00565	COG0753	catalase activity
FOC85_00575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC85_00605	COG0778	Nitroreductase
FOC85_00610	COG1846	Transcriptional regulator
FOC85_00645	COG1725	Transcriptional regulator
FOC85_00665	COG1136	(ABC) transporter
FOC85_00665	COG0577	efflux transmembrane transporter activity
FOC85_00690	COG2207	Transcriptional regulator
FOC85_00695	COG0456	acetyltransferase
FOC85_00715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_00755	COG0730	response to heat
FOC85_00765	COG0833	amino acid
FOC85_00775	COG4335	DNA alkylation repair
FOC85_00835	COG1984	allophanate hydrolase subunit 2
FOC85_00840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC85_00845	COG1414	Transcriptional regulator
FOC85_00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC85_00865	COG0640	Transcriptional regulator
FOC85_00875	COG1960	acyl-CoA dehydrogenase activity
FOC85_00925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_00940	COG5577	PFAM Coat F domain
FOC85_00945	COG3403	YqcI/YcgG family
FOC85_00950	COG1280	lysine exporter protein (LysE YggA)
FOC85_00955	COG1113	amino acid transport
FOC85_00985	COG1063	alcohol dehydrogenase
FOC85_00995	COG1027	Aspartate ammonia-lyase
FOC85_01000	COG0252	asparaginase activity
FOC85_01005	COG1396	sequence-specific DNA binding
FOC85_01060	COG2207	Transcriptional regulator
FOC85_01080	COG0322	excinuclease ABC activity
FOC85_01085	COG0531	amino acid
FOC85_01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC85_01100	COG0784	Response regulator, receiver
FOC85_01105	COG4191	Histidine kinase
FOC85_01110	COG2066	Belongs to the glutaminase family
FOC85_01115	COG1115	amino acid carrier protein
FOC85_01145	COG0737	Belongs to the 5'-nucleotidase family
FOC85_01150	COG2329	Antibiotic biosynthesis monooxygenase
FOC85_01160	COG0598	Magnesium transport protein CorA
FOC85_01195	COG0415	Belongs to the DNA photolyase family
FOC85_01200	COG0288	reversible hydration of carbon dioxide
FOC85_01210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC85_01215	COG5609	conserved protein (DUF2294)
FOC85_01230	COG0714	Associated with various cellular activities
FOC85_01240	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC85_01245	COG2267	carboxylic ester hydrolase activity
FOC85_01250	COG4641	Protein conserved in bacteria
FOC85_01255	COG1136	(ABC) transporter
FOC85_01260	COG0577	efflux transmembrane transporter activity
FOC85_01275	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC85_01280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC85_01285	COG1121	(ABC) transporter
FOC85_01310	COG0798	PFAM Bile acid sodium symporter
FOC85_01315	COG0346	lactoylglutathione lyase activity
FOC85_01320	COG0640	Transcriptional regulator
FOC85_01335	COG0443	Heat shock 70 kDa protein
FOC85_01355	COG0346	lactoylglutathione lyase activity
FOC85_01375	COG2814	Major facilitator Superfamily
FOC85_01400	COG0745	RESPONSE REGULATOR receiver
FOC85_01405	COG3850	Histidine kinase
FOC85_01405	COG5002	protein histidine kinase activity
FOC85_01430	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC85_01455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_01460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC85_01470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC85_01485	COG2309	aminopeptidase activity
FOC85_01495	COG0789	Transcriptional regulator
FOC85_01500	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC85_01520	COG0577	efflux transmembrane transporter activity
FOC85_01535	COG5002	protein histidine kinase activity
FOC85_01535	COG3850	Histidine kinase
FOC85_01545	COG2364	Membrane
FOC85_01550	COG1846	Transcriptional regulator
FOC85_01555	COG0456	acetyltransferase
FOC85_01560	COG2808	Putative FMN-binding domain
FOC85_01565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_01580	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC85_01595	COG1252	NADH dehydrogenase
FOC85_01600	COG3227	Zinc metalloprotease (Elastase)
FOC85_01605	COG0584	glycerophosphoryl diester phosphodiesterase
FOC85_01645	COG0738	Major facilitator superfamily
FOC85_01650	COG0673	inositol 2-dehydrogenase activity
FOC85_01655	COG0561	phosphatase activity
FOC85_01660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC85_01665	COG1609	Transcriptional regulator
FOC85_01670	COG0457	Tetratricopeptide repeat
FOC85_01695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC85_01720	COG0814	amino acid
FOC85_01725	COG1760	l-serine dehydratase
FOC85_01730	COG1760	l-serine dehydratase
FOC85_01735	COG2184	nucleotidyltransferase activity
FOC85_01740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC85_01745	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC85_01755	COG1335	isochorismatase
FOC85_01760	COG1522	sequence-specific DNA binding
FOC85_01765	COG0531	amino acid
FOC85_01780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC85_01800	COG0662	Cupin 2, conserved barrel domain protein
FOC85_01805	COG2207	Transcriptional regulator
FOC85_01805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_01835	COG3409	Peptidoglycan-binding domain 1 protein
FOC85_01835	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC85_01875	COG0477	Major facilitator Superfamily
FOC85_01885	COG1846	Transcriptional regulator
FOC85_01890	COG2814	Major facilitator Superfamily
FOC85_01900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC85_01905	COG1131	(ABC) transporter
FOC85_01930	COG1309	transcriptional regulator
FOC85_01945	COG2031	fatty acid transporter
FOC85_01955	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC85_01990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC85_02005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC85_02010	COG1288	antiporter activity
FOC85_02015	COG2356	endonuclease I
FOC85_02020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC85_02050	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC85_02050	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC85_02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_02060	COG0506	proline dehydrogenase activity
FOC85_02075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC85_02085	COG2197	response regulator
FOC85_02105	COG1733	regulation of RNA biosynthetic process
FOC85_02110	COG0778	Nitroreductase
FOC85_02130	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_02140	COG1131	(ABC) transporter
FOC85_02165	COG1011	Hydrolase
FOC85_02215	COG0346	lactoylglutathione lyase activity
FOC85_02220	COG1940	carbohydrate kinase activity
FOC85_02225	COG0738	Major facilitator superfamily
FOC85_02230	COG0110	maltose O-acetyltransferase activity
FOC85_02235	COG0628	permease
FOC85_02255	COG2226	methyltransferase
FOC85_02265	COG0477	Major facilitator Superfamily
FOC85_02295	COG1253	flavin adenine dinucleotide binding
FOC85_02300	COG0789	Transcriptional regulator
FOC85_02305	COG0697	spore germination
FOC85_02310	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC85_02315	COG3813	Protein conserved in bacteria
FOC85_02320	COG2706	6-phosphogluconolactonase activity
FOC85_02325	COG1070	Carbohydrate kinase
FOC85_02335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC85_02340	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC85_02350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC85_02370	COG0814	amino acid
FOC85_02395	COG1393	Belongs to the ArsC family
FOC85_02405	COG2188	Transcriptional regulator
FOC85_02410	COG0673	inositol 2-dehydrogenase activity
FOC85_02425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_02445	COG0384	phenazine biosynthesis protein PhzF
FOC85_02455	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_02475	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC85_02480	COG1733	regulation of RNA biosynthetic process
FOC85_02510	COG1191	sigma factor activity
FOC85_02520	COG1266	CAAX protease self-immunity
FOC85_02525	COG1309	transcriptional regulator
FOC85_02545	COG3152	Membrane
FOC85_02595	COG1151	hydroxylamine reductase activity
FOC85_02605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_02610	COG3757	hydrolase, family 25
FOC85_02610	COG3409	Peptidoglycan-binding domain 1 protein
FOC85_02645	COG2072	flavoprotein involved in K transport
FOC85_02675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_02690	COG1695	Transcriptional regulator
FOC85_02695	COG0604	alcohol dehydrogenase
FOC85_02700	COG1113	amino acid transport
FOC85_02705	COG2814	Major facilitator Superfamily
FOC85_02735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC85_02740	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC85_02755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_02760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_02765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_02770	COG3739	integral membrane protein
FOC85_02775	COG0384	phenazine biosynthesis protein PhzF
FOC85_02795	COG0583	DNA-binding transcription factor activity
FOC85_02815	COG1193	negative regulation of DNA recombination
FOC85_02835	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOC85_02840	COG1164	Oligoendopeptidase f
FOC85_02845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC85_02875	COG0584	glycerophosphoryl diester phosphodiesterase
FOC85_02900	COG0640	Transcriptional regulator
FOC85_02905	COG0604	alcohol dehydrogenase
FOC85_02915	COG0457	Tetratricopeptide repeat
FOC85_02925	COG2808	Putative FMN-binding domain
FOC85_02940	COG0385	Bile acid
FOC85_02945	COG0277	FAD linked oxidase domain protein
FOC85_02975	COG1216	Glycosyl transferase, family 2
FOC85_02980	COG1024	Enoyl-CoA hydratase
FOC85_02990	COG1285	pathogenesis
FOC85_03005	COG2514	catechol 2,3-dioxygenase activity
FOC85_03010	COG2720	vancomycin resistance protein
FOC85_03045	COG0716	FMN binding
FOC85_03075	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_03085	COG0165	Argininosuccinate lyase
FOC85_03100	COG4145	pantothenate transmembrane transporter activity
FOC85_03110	COG1012	belongs to the aldehyde dehydrogenase family
FOC85_03115	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_03125	COG1657	PFAM Prenyltransferase squalene oxidase
FOC85_03130	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC85_03135	COG2962	Rard protein
FOC85_03140	COG3326	Membrane
FOC85_03155	COG0489	protein tyrosine kinase activity
FOC85_03165	COG0314	molybdopterin synthase activity
FOC85_03170	COG0303	'Molybdopterin
FOC85_03175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC85_03180	COG2116	formate transmembrane transporter activity
FOC85_03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC85_03195	COG5609	conserved protein (DUF2294)
FOC85_03200	COG2427	Protein of unknown function (DUF1641)
FOC85_03205	COG3383	formate dehydrogenase (NAD+) activity
FOC85_03210	COG0697	spore germination
FOC85_03250	COG2226	methyltransferase
FOC85_03255	COG4166	transmembrane transport
FOC85_03265	COG4166	transmembrane transport
FOC85_03270	COG4166	transmembrane transport
FOC85_03275	COG1301	dicarboxylic acid transport
FOC85_03280	COG1316	TRANSCRIPTIONal
FOC85_03290	COG1595	DNA-templated transcription, initiation
FOC85_03310	COG1131	(ABC) transporter
FOC85_03320	COG0673	inositol 2-dehydrogenase activity
FOC85_03330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC85_03335	COG0187	DNA topoisomerase II activity
FOC85_03340	COG1832	CoA-binding protein
FOC85_03345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC85_03350	COG0745	RESPONSE REGULATOR receiver
FOC85_03370	COG4841	protein insertion into membrane
FOC85_03375	COG0824	Thioesterase
FOC85_03405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC85_03415	COG2274	protein secretion by the type I secretion system
FOC85_03420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC85_03460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC85_03475	COG0183	Belongs to the thiolase family
FOC85_03480	COG0318	PFAM AMP-dependent synthetase and ligase
FOC85_03485	COG1268	BioY protein
FOC85_03490	COG0318	PFAM AMP-dependent synthetase and ligase
FOC85_03540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_03550	COG5002	protein histidine kinase activity
FOC85_03555	COG0400	carboxylic ester hydrolase activity
FOC85_03560	COG0346	lactoylglutathione lyase activity
FOC85_03565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC85_03570	COG0069	glutamate synthase activity
FOC85_03575	COG1902	pentaerythritol trinitrate reductase activity
FOC85_03580	COG1329	Transcriptional regulator
FOC85_03585	COG0010	Belongs to the arginase family
FOC85_03610	COG2226	methyltransferase
FOC85_03650	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC85_03655	COG0785	Cytochrome C biogenesis protein
FOC85_03665	COG1473	amidohydrolase
FOC85_03675	COG1131	(ABC) transporter
FOC85_03685	COG0583	DNA-binding transcription factor activity
FOC85_03695	COG1346	cytolysis
FOC85_03710	COG0730	response to heat
FOC85_03720	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC85_03720	COG3409	Peptidoglycan-binding domain 1 protein
FOC85_03735	COG1132	(ABC) transporter
FOC85_03740	COG1132	(ABC) transporter
FOC85_03765	COG3639	organic phosphonate transmembrane transporter activity
FOC85_03780	COG0737	Belongs to the 5'-nucleotidase family
FOC85_03790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC85_03810	COG1695	Transcriptional regulator
FOC85_03815	COG0174	glutamine synthetase
FOC85_03820	COG0789	Transcriptional regulator
FOC85_03825	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC85_03830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC85_03835	COG2860	membrane
FOC85_03840	COG0464	growth
FOC85_03870	COG3584	3D domain protein
FOC85_03870	COG1388	LysM domain
FOC85_03875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC85_03875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC85_03875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC85_03880	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC85_03885	COG1349	DNA-binding transcription factor activity
FOC85_03890	COG1979	alcohol dehydrogenase
FOC85_03895	COG2322	membrane
FOC85_03905	COG1113	amino acid transport
FOC85_03920	COG1408	metallophosphoesterase
FOC85_03925	COG2116	formate transmembrane transporter activity
FOC85_03935	COG2217	Heavy metal translocating P-type atpase
FOC85_03940	COG2608	mercury ion transmembrane transporter activity
FOC85_03945	COG1937	Protein conserved in bacteria
FOC85_03965	COG2819	hydrolase of the alpha beta superfamily
FOC85_03970	COG1120	ATPase activity
FOC85_03975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_03980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_03985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_03990	COG0708	Exodeoxyribonuclease III
FOC85_03995	COG2169	Transcriptional regulator
FOC85_04000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC85_04005	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC85_04015	COG2364	Membrane
FOC85_04030	COG2267	carboxylic ester hydrolase activity
FOC85_04035	COG0346	lactoylglutathione lyase activity
FOC85_04040	COG3300	MHYT domain
FOC85_04040	COG5001	Diguanylate cyclase
FOC85_04100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_04125	COG1404	Belongs to the peptidase S8 family
FOC85_04130	COG3773	Cell wall hydrolase
FOC85_04140	COG1368	sulfuric ester hydrolase activity
FOC85_04145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC85_04155	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC85_04175	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC85_04185	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC85_04190	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC85_04190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC85_04200	COG2359	stage V sporulation protein S
FOC85_04205	COG1692	metallophosphoesterase
FOC85_04225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC85_04230	COG1426	Protein conserved in bacteria
FOC85_04245	COG0300	oxidoreductase activity
FOC85_04250	COG0612	Peptidase, M16
FOC85_04255	COG0612	Peptidase, M16
FOC85_04280	COG2188	Transcriptional regulator
FOC85_04285	COG1674	ftsk spoiiie
FOC85_04295	COG0740	serine-type endopeptidase activity
FOC85_04300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC85_04310	COG0527	aspartate kinase activity
FOC85_04315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC85_04320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC85_04325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC85_04330	COG1873	PFAM PRC-barrel domain
FOC85_04335	COG0612	Peptidase, M16
FOC85_04340	COG0726	polysaccharide deacetylase
FOC85_04355	COG0196	riboflavin kinase activity
FOC85_04370	COG1550	Protein conserved in bacteria
FOC85_04380	COG1358	cellular component organization or biogenesis
FOC85_04385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC85_04390	COG0195	Participates in both transcription termination and antitermination
FOC85_04420	COG0750	zinc metalloprotease
FOC85_04430	COG4589	Belongs to the CDS family
FOC85_04445	COG0528	UMP kinase activity
FOC85_04475	COG4974	Belongs to the 'phage' integrase family
FOC85_04485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC85_04490	COG0758	DNA mediated transformation
FOC85_04495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC85_04535	COG1837	Belongs to the UPF0109 family
FOC85_04545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC85_04555	COG0552	protein localization to endoplasmic reticulum
FOC85_04560	COG1196	nuclear chromosome segregation
FOC85_04570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC85_04575	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_04580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC85_04595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC85_04600	COG1461	Dihydroxyacetone kinase
FOC85_04605	COG1302	Protein conserved in bacteria
FOC85_04620	COG1564	THIamine pyrophosphokinase
FOC85_04625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC85_04630	COG1162	GTPase activity
FOC85_04635	COG0515	serine threonine protein kinase
FOC85_04635	COG2815	serine threonine protein kinase
FOC85_04640	COG0631	protein serine/threonine phosphatase activity
FOC85_04650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC85_04650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC85_04660	COG0242	peptide deformylase activity
FOC85_04665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC85_04670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC85_04690	COG1561	YicC-like family, N-terminal region
FOC85_04695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC85_04705	COG0006	proline dipeptidase activity
FOC85_04725	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC85_04795	COG0564	pseudouridine synthase activity
FOC85_04815	COG3599	regulation of cell shape
FOC85_04820	COG2302	S4 RNA-binding domain
FOC85_04825	COG0762	integral membrane protein
FOC85_04835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC85_04845	COG1873	PFAM PRC-barrel domain
FOC85_04850	COG1191	sigma factor activity
FOC85_04855	COG1191	sigma factor activity
FOC85_04865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC85_04870	COG0849	cell division
FOC85_04875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC85_04880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC85_04890	COG0772	Belongs to the SEDS family
FOC85_04905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC85_04910	COG0768	penicillin binding
FOC85_04920	COG4839	cell division protein FtsL
FOC85_04935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC85_04950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC85_04955	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC85_04965	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC85_04970	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC85_04975	COG3314	Sporulation integral membrane protein YlbJ
FOC85_04985	COG0742	ribosomal rna small subunit methyltransferase
FOC85_05000	COG3679	Belongs to the UPF0342 family
FOC85_05005	COG0406	alpha-ribazole phosphatase activity
FOC85_05020	COG2340	Cysteine-rich secretory protein family
FOC85_05035	COG3336	cytochrome c oxidase
FOC85_05070	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC85_05075	COG0772	Belongs to the SEDS family
FOC85_05085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC85_05090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC85_05100	COG4896	Protein conserved in bacteria
FOC85_05125	COG0483	inositol monophosphate 1-phosphatase activity
FOC85_05145	COG1982	Orn Lys Arg decarboxylase major
FOC85_05195	COG0022	dehydrogenase e1 component
FOC85_05200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC85_05210	COG0242	peptide deformylase activity
FOC85_05215	COG0561	phosphatase activity
FOC85_05225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC85_05230	COG0569	domain protein
FOC85_05250	COG0583	DNA-binding transcription factor activity
FOC85_05255	COG0517	IMP dehydrogenase activity
FOC85_05265	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC85_05275	COG4703	Protein of unknown function (DUF1797)
FOC85_05290	COG2200	EAL domain
FOC85_05295	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_05300	COG1408	metallophosphoesterase
FOC85_05310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC85_05345	COG2814	Major facilitator Superfamily
FOC85_05365	COG3209	COG3209 Rhs family protein
FOC85_05375	COG2205	protein histidine kinase activity
FOC85_05385	COG0436	Aminotransferase
FOC85_05390	COG1609	Transcriptional regulator
FOC85_05395	COG3833	ABC-type maltose transport systems, permease component
FOC85_05400	COG1175	transmembrane transport
FOC85_05405	COG2182	Extracellular solute-binding protein
FOC85_05415	COG0366	Alpha amylase catalytic
FOC85_05420	COG3842	ATPase activity
FOC85_05460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC85_05465	COG0183	Belongs to the thiolase family
FOC85_05495	COG1695	Transcriptional regulator
FOC85_05500	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_05520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC85_05525	COG0436	Aminotransferase
FOC85_05560	COG2084	Dehydrogenase
FOC85_05565	COG2203	Gaf domain
FOC85_05565	COG2199	diguanylate cyclase activity
FOC85_05570	COG0778	Nitroreductase
FOC85_05595	COG2190	(PTS) system
FOC85_05595	COG1263	PTS System
FOC85_05595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC85_05600	COG3711	transcriptional antiterminator
FOC85_05610	COG2188	Transcriptional regulator
FOC85_05620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC85_05645	COG1547	Domain of unknown function (DUF309)
FOC85_05650	COG0456	acetyltransferase
FOC85_05655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC85_05660	COG4086	secreted protein
FOC85_05665	COG0561	phosphatase activity
FOC85_05670	COG0697	spore germination
FOC85_05685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC85_05710	COG0733	neurotransmitter:sodium symporter activity
FOC85_05730	COG1686	Belongs to the peptidase S11 family
FOC85_05735	COG1725	Transcriptional regulator
FOC85_05740	COG1131	(ABC) transporter
FOC85_05755	COG1846	Transcriptional regulator
FOC85_05770	COG0598	Magnesium transport protein CorA
FOC85_05795	COG4974	Belongs to the 'phage' integrase family
FOC85_05805	COG0735	belongs to the Fur family
FOC85_05810	COG1300	Membrane
FOC85_05830	COG0667	Aldo Keto reductase
FOC85_05835	COG0656	L-ascorbic acid biosynthetic process
FOC85_05840	COG0456	acetyltransferase
FOC85_05840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC85_05850	COG1525	nuclease
FOC85_05850	COG0737	Belongs to the 5'-nucleotidase family
FOC85_05850	COG4085	toxin activity
FOC85_05860	COG0596	Alpha beta hydrolase
FOC85_05865	COG2056	Na+-H+ antiporter family
FOC85_05870	COG1609	Transcriptional regulator
FOC85_05875	COG0456	acetyltransferase
FOC85_05880	COG1073	alpha beta
FOC85_05895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC85_05895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC85_05900	COG0307	riboflavin synthase, alpha
FOC85_05925	COG4106	trans-aconitate 2-methyltransferase activity
FOC85_05930	COG2226	methyltransferase
FOC85_05930	COG1073	alpha beta
FOC85_05945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC85_05960	COG0737	Belongs to the 5'-nucleotidase family
FOC85_05970	COG1522	sequence-specific DNA binding
FOC85_05990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC85_06000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC85_06015	COG0300	oxidoreductase activity
FOC85_06020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_06025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC85_06030	COG1760	l-serine dehydratase
FOC85_06035	COG1760	l-serine dehydratase
FOC85_06055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC85_06065	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC85_06070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_06085	COG1376	ErfK ybiS ycfS ynhG family protein
FOC85_06090	COG4129	membrane
FOC85_06095	COG1126	abc transporter atp-binding protein
FOC85_06100	COG0765	amino acid transport
FOC85_06105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC85_06120	COG2816	NAD+ diphosphatase activity
FOC85_06125	COG0772	Belongs to the SEDS family
FOC85_06130	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC85_06135	COG0022	dehydrogenase e1 component
FOC85_06140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC85_06145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC85_06160	COG0280	phosphate acetyltransferase
FOC85_06165	COG3829	transcription factor binding
FOC85_06165	COG3290	protein histidine kinase activity
FOC85_06175	COG0584	glycerophosphoryl diester phosphodiesterase
FOC85_06180	COG3093	addiction module antidote protein HigA
FOC85_06190	COG0745	RESPONSE REGULATOR receiver
FOC85_06195	COG0750	zinc metalloprotease
FOC85_06200	COG0497	DNA recombination
FOC85_06210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC85_06220	COG0142	geranyltranstransferase activity
FOC85_06245	COG1302	Protein conserved in bacteria
FOC85_06250	COG0439	Biotin carboxylase
FOC85_06255	COG0511	ligase activity, forming carbon-carbon bonds
FOC85_06300	COG3854	ATPases associated with a variety of cellular activities
FOC85_06325	COG0006	proline dipeptidase activity
FOC85_06340	COG3872	metal-dependent enzyme
FOC85_06350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC85_06365	COG1695	Transcriptional regulator
FOC85_06380	COG0095	Lipoate-protein ligase
FOC85_06385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC85_06390	COG1609	Transcriptional regulator
FOC85_06400	COG2076	Multidrug Resistance protein
FOC85_06405	COG2076	Multidrug Resistance protein
FOC85_06440	COG1131	(ABC) transporter
FOC85_06445	COG1725	Transcriptional regulator
FOC85_06475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC85_06530	COG4970	Tfp pilus assembly protein FimT
FOC85_06540	COG1459	type II secretion system
FOC85_06545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC85_06595	COG1410	methionine synthase
FOC85_06595	COG0646	methionine synthase
FOC85_06600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC85_06600	COG0646	methionine synthase
FOC85_06605	COG0626	cystathionine gamma-synthase activity
FOC85_06610	COG0626	cystathionine gamma-synthase activity
FOC85_06630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_06640	COG1940	carbohydrate kinase activity
FOC85_06645	COG4483	Protein conserved in bacteria
FOC85_06650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC85_06655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC85_06660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC85_06665	COG0704	Plays a role in the regulation of phosphate uptake
FOC85_06675	COG0581	inorganic phosphate transmembrane transporter activity
FOC85_06680	COG0573	inorganic phosphate transmembrane transporter activity
FOC85_06685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC85_06695	COG0477	Major facilitator Superfamily
FOC85_06700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC85_06725	COG0735	belongs to the Fur family
FOC85_06730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC85_06735	COG1121	(ABC) transporter
FOC85_06740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_06770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC85_06775	COG2384	SAM-dependent methyltransferase
FOC85_06780	COG2010	Cytochrome c
FOC85_06785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC85_06790	COG0358	DNA primase activity
FOC85_06805	COG0517	IMP dehydrogenase activity
FOC85_06820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC85_06825	COG0295	cytidine deaminase activity
FOC85_06830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC85_06840	COG1480	7TM receptor with intracellular HD hydrolase
FOC85_06845	COG1702	phosphate starvation-inducible protein PhoH
FOC85_06860	COG1610	YqeY-like protein
FOC85_06865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC85_06870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC85_06875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC85_06905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC85_06910	COG1733	regulation of RNA biosynthetic process
FOC85_06935	COG1466	dna polymerase III delta subunit
FOC85_06945	COG0658	competence protein
FOC85_06945	COG2333	competence protein COMEC
FOC85_06950	COG2131	deaminase
FOC85_06955	COG1596	polysaccharide export
FOC85_06955	COG1555	photosystem II stabilization
FOC85_06960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC85_06965	COG2226	methyltransferase
FOC85_06970	COG0799	negative regulation of ribosome biogenesis
FOC85_06975	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC85_06985	COG1534	Rna-binding protein
FOC85_06995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC85_07000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC85_07045	COG0778	Nitroreductase
FOC85_07050	COG2357	RelA SpoT domain protein
FOC85_07060	COG1785	Belongs to the alkaline phosphatase family
FOC85_07070	COG2267	carboxylic ester hydrolase activity
FOC85_07105	COG1404	Belongs to the peptidase S8 family
FOC85_07110	COG3186	Phenylalanine-4-hydroxylase
FOC85_07120	COG2514	catechol 2,3-dioxygenase activity
FOC85_07125	COG2259	Doxx family
FOC85_07165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_07175	COG1454	alcohol dehydrogenase
FOC85_07175	COG1012	belongs to the aldehyde dehydrogenase family
FOC85_07180	COG0626	cystathionine gamma-synthase activity
FOC85_07185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC85_07210	COG0768	penicillin binding
FOC85_07235	COG4122	O-methyltransferase activity
FOC85_07240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC85_07270	COG0628	permease
FOC85_07290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC85_07305	COG1104	cysteine desulfurase activity
FOC85_07310	COG1959	2 iron, 2 sulfur cluster binding
FOC85_07315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC85_07325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC85_07350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC85_07360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC85_07360	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC85_07365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC85_07370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC85_07370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC85_07380	COG2244	polysaccharide biosynthetic process
FOC85_07385	COG2323	membrane
FOC85_07395	COG1862	Preprotein translocase
FOC85_07425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC85_07435	COG0697	spore germination
FOC85_07440	COG0640	Transcriptional regulator
FOC85_07465	COG0157	Belongs to the NadC ModD family
FOC85_07470	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC85_07475	COG1104	cysteine desulfurase activity
FOC85_07480	COG1827	regulation of RNA biosynthetic process
FOC85_07485	COG2258	MOSC domain
FOC85_07490	COG0077	Prephenate dehydratase
FOC85_07495	COG0577	efflux transmembrane transporter activity
FOC85_07500	COG0577	efflux transmembrane transporter activity
FOC85_07505	COG1136	(ABC) transporter
FOC85_07510	COG5002	protein histidine kinase activity
FOC85_07515	COG0745	RESPONSE REGULATOR receiver
FOC85_07525	COG3290	protein histidine kinase activity
FOC85_07535	COG2868	ribosomal protein
FOC85_07545	COG1530	ribonuclease E activity
FOC85_07550	COG1994	Peptidase M50
FOC85_07555	COG0739	heme binding
FOC85_07560	COG2894	cell division
FOC85_07580	COG1077	Cell shape determining protein MreB Mrl
FOC85_07660	COG0285	dihydrofolate synthase activity
FOC85_07675	COG1388	LysM domain
FOC85_07685	COG0113	porphobilinogen synthase activity
FOC85_07690	COG1587	Uroporphyrinogen-III synthase
FOC85_07700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC85_07710	COG1846	Transcriptional regulator
FOC85_07715	COG1764	response to oxidative stress
FOC85_07730	COG1067	ATP-dependent peptidase activity
FOC85_07730	COG0470	DNA polymerase III
FOC85_07775	COG0622	Phosphoesterase
FOC85_07790	COG5401	PFAM Sporulation and spore germination
FOC85_07810	COG1309	transcriptional regulator
FOC85_07825	COG2197	response regulator
FOC85_07830	COG2233	PERMEase
FOC85_07835	COG0402	S-adenosylhomocysteine deaminase activity
FOC85_07840	COG1983	PspC domain protein
FOC85_07845	COG1396	sequence-specific DNA binding
FOC85_07850	COG0697	spore germination
FOC85_07860	COG1959	2 iron, 2 sulfur cluster binding
FOC85_07865	COG1668	transmembrane transport
FOC85_07870	COG4152	abc transporter atp-binding protein
FOC85_07875	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC85_07880	COG1360	Flagellar Motor Protein
FOC85_07885	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC85_07890	COG1876	peptidase activity
FOC85_07895	COG0824	Thioesterase
FOC85_07900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC85_07905	COG1053	succinate dehydrogenase
FOC85_07910	COG2009	succinate dehydrogenase
FOC85_07915	COG1719	4-vinyl reductase, 4VR
FOC85_07925	COG3118	belongs to the thioredoxin family
FOC85_07930	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC85_07935	COG2086	electron transfer activity
FOC85_07940	COG1024	Enoyl-CoA hydratase
FOC85_07945	COG1309	transcriptional regulator
FOC85_07950	COG0318	PFAM AMP-dependent synthetase and ligase
FOC85_07970	COG2318	DinB family
FOC85_07995	COG1131	(ABC) transporter
FOC85_08000	COG2205	protein histidine kinase activity
FOC85_08005	COG0745	RESPONSE REGULATOR receiver
FOC85_08015	COG4895	conserved protein (DUF2196)
FOC85_08020	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC85_08035	COG4509	Sortase family
FOC85_08040	COG1120	ATPase activity
FOC85_08055	COG5386	Cell surface protein
FOC85_08060	COG5386	Cell surface protein
FOC85_08065	COG1114	Component of the transport system for branched-chain amino acids
FOC85_08070	COG1187	pseudouridine synthase activity
FOC85_08080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC85_08080	COG1796	DNA polymerase
FOC85_08085	COG1286	toxin biosynthetic process
FOC85_08130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC85_08140	COG1418	mRNA catabolic process
FOC85_08175	COG2814	Major facilitator Superfamily
FOC85_08180	COG1566	PFAM secretion protein HlyD family protein
FOC85_08185	COG1309	transcriptional regulator
FOC85_08190	COG1363	Peptidase, m42
FOC85_08215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC85_08225	COG1484	DNA-dependent DNA replication
FOC85_08230	COG3611	Membrane attachment protein
FOC85_08240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC85_08245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC85_08250	COG0237	dephospho-CoA kinase activity
FOC85_08255	COG1971	Probably functions as a manganese efflux pump
FOC85_08265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC85_08265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC85_08270	COG5002	protein histidine kinase activity
FOC85_08275	COG0745	RESPONSE REGULATOR receiver
FOC85_08295	COG0538	isocitrate dehydrogenase activity
FOC85_08300	COG0372	Belongs to the citrate synthase family
FOC85_08310	COG0628	permease
FOC85_08315	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC85_08340	COG1725	Transcriptional regulator
FOC85_08345	COG0281	malic enzyme
FOC85_08350	COG0587	DNA-directed DNA polymerase activity
FOC85_08365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC85_08380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC85_08390	COG4109	DRTGG domain
FOC85_08405	COG0006	proline dipeptidase activity
FOC85_08450	COG0662	Cupin 2, conserved barrel domain protein
FOC85_08460	COG1476	TRANSCRIPTIONal
FOC85_08475	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_08480	COG0589	response to stress
FOC85_08520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_08535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC85_08540	COG0827	DNA restriction-modification system
FOC85_08545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC85_08550	COG3874	Sporulation protein YtfJ
FOC85_08565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC85_08575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC85_08590	COG1104	cysteine desulfurase activity
FOC85_08600	COG0583	DNA-binding transcription factor activity
FOC85_08605	COG0697	spore germination
FOC85_08610	COG1309	transcriptional regulator
FOC85_08615	COG1956	GAF domain-containing protein
FOC85_08620	COG0626	cystathionine gamma-synthase activity
FOC85_08670	COG1595	DNA-templated transcription, initiation
FOC85_08680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC85_08685	COG0454	-acetyltransferase
FOC85_08690	COG0517	IMP dehydrogenase activity
FOC85_08695	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC85_08710	COG0745	RESPONSE REGULATOR receiver
FOC85_08720	COG0666	response to abiotic stimulus
FOC85_08755	COG1609	Transcriptional regulator
FOC85_08760	COG4851	CamS sex pheromone cAM373 precursor
FOC85_08765	COG3118	belongs to the thioredoxin family
FOC85_08775	COG2309	aminopeptidase activity
FOC85_08795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_08810	COG1674	ftsk spoiiie
FOC85_08820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC85_08830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC85_08835	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC85_08840	COG1363	Peptidase, m42
FOC85_08850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_08865	COG0510	thiamine kinase activity
FOC85_08870	COG1523	belongs to the glycosyl hydrolase 13 family
FOC85_08880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC85_08885	COG1349	DNA-binding transcription factor activity
FOC85_08890	COG1187	pseudouridine synthase activity
FOC85_08895	COG2244	polysaccharide biosynthetic process
FOC85_08900	COG2081	HI0933 family
FOC85_08905	COG2814	Major facilitator Superfamily
FOC85_08915	COG3832	glyoxalase III activity
FOC85_08935	COG1329	Transcriptional regulator
FOC85_08960	COG0314	molybdopterin synthase activity
FOC85_08965	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC85_08970	COG0303	'Molybdopterin
FOC85_08980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC85_08985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC85_09005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC85_09015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC85_09060	COG2814	Major facilitator Superfamily
FOC85_09065	COG0475	glutathione-regulated potassium exporter activity
FOC85_09070	COG0490	domain, Protein
FOC85_09075	COG0582	viral genome integration into host DNA
FOC85_09085	COG1136	(ABC) transporter
FOC85_09105	COG1242	4 iron, 4 sulfur cluster binding
FOC85_09110	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC85_09125	COG1794	racemase activity, acting on amino acids and derivatives
FOC85_09135	COG5504	Zn-dependent protease
FOC85_09160	COG2267	carboxylic ester hydrolase activity
FOC85_09165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC85_09170	COG0671	phosphoesterase, PA-phosphatase related
FOC85_09175	COG0438	transferase activity, transferring glycosyl groups
FOC85_09185	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC85_09250	COG0546	phosphoglycolate phosphatase activity
FOC85_09255	COG1349	DNA-binding transcription factor activity
FOC85_09265	COG5002	protein histidine kinase activity
FOC85_09270	COG4191	Histidine kinase
FOC85_09275	COG2267	carboxylic ester hydrolase activity
FOC85_09280	COG1368	sulfuric ester hydrolase activity
FOC85_09295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC85_09300	COG1116	anion transmembrane transporter activity
FOC85_09305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC85_09320	COG0546	phosphoglycolate phosphatase activity
FOC85_09330	COG0494	nUDIX hydrolase
FOC85_09365	COG0288	reversible hydration of carbon dioxide
FOC85_09370	COG1271	oxidase subunit
FOC85_09375	COG1294	oxidase, subunit
FOC85_09395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_09420	COG1842	Phage shock protein A
FOC85_09480	COG3859	Proton-coupled thiamine transporter YuaJ
FOC85_09485	COG5002	protein histidine kinase activity
FOC85_09490	COG0745	RESPONSE REGULATOR receiver
FOC85_09520	COG1597	lipid kinase activity
FOC85_09550	COG0586	Pfam SNARE associated Golgi protein
FOC85_09560	COG4977	sequence-specific DNA binding
FOC85_09570	COG0577	efflux transmembrane transporter activity
FOC85_09575	COG1136	(ABC) transporter
FOC85_09580	COG2207	Transcriptional regulator
FOC85_09580	COG3708	Transcriptional regulator
FOC85_09585	COG0745	RESPONSE REGULATOR receiver
FOC85_09590	COG2205	protein histidine kinase activity
FOC85_09595	COG0577	efflux transmembrane transporter activity
FOC85_09600	COG0577	efflux transmembrane transporter activity
FOC85_09605	COG1136	(ABC) transporter
FOC85_09610	COG0577	efflux transmembrane transporter activity
FOC85_09625	COG2188	Transcriptional regulator
FOC85_09645	COG3964	amidohydrolase
FOC85_09665	COG4948	Mandelate Racemase Muconate Lactonizing
FOC85_09675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC85_09680	COG0596	Alpha beta hydrolase
FOC85_09690	COG1169	isochorismate synthase
FOC85_09695	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC85_09700	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC85_09720	COG0058	SHG alpha-glucan phosphorylase activity
FOC85_09730	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC85_09750	COG1404	Belongs to the peptidase S8 family
FOC85_09850	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC85_09885	COG1285	pathogenesis
FOC85_09890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC85_09905	COG2155	Conserved Protein
FOC85_09910	COG1098	S1 RNA binding domain
FOC85_09915	COG0436	Aminotransferase
FOC85_09920	COG1522	sequence-specific DNA binding
FOC85_09925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC85_09930	COG2267	carboxylic ester hydrolase activity
FOC85_09940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC85_09960	COG5018	Exonuclease
FOC85_09965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC85_09985	COG2050	protein possibly involved in aromatic compounds catabolism
FOC85_09995	COG1268	BioY protein
FOC85_10000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC85_10005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC85_10020	COG3584	3D domain protein
FOC85_10035	COG1252	NADH dehydrogenase
FOC85_10050	COG3708	Transcriptional regulator
FOC85_10065	COG1683	Conserved Protein
FOC85_10075	COG0316	Belongs to the HesB IscA family
FOC85_10090	COG1252	NADH dehydrogenase
FOC85_10100	COG2274	protein secretion by the type I secretion system
FOC85_10105	COG0390	transport system, permease component
FOC85_10110	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC85_10130	COG4837	Protein of unknown function (DUF1462)
FOC85_10135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC85_10145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC85_10150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC85_10165	COG1136	(ABC) transporter
FOC85_10165	COG0577	efflux transmembrane transporter activity
FOC85_10170	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC85_10175	COG0647	UMP catabolic process
FOC85_10185	COG2445	Protein of unknown function DUF86
FOC85_10190	COG1494	fructose-1,6-bisphosphatase
FOC85_10205	COG4470	Protein conserved in bacteria
FOC85_10215	COG0789	Transcriptional regulator
FOC85_10220	COG4377	Putative membrane peptidase family (DUF2324)
FOC85_10245	COG0739	heme binding
FOC85_10255	COG3377	Domain of unknown function (DUF1805)
FOC85_10260	COG0737	Belongs to the 5'-nucleotidase family
FOC85_10265	COG1695	Transcriptional regulator
FOC85_10275	COG0719	Fe-S assembly protein
FOC85_10280	COG0822	iron-sulfur transferase activity
FOC85_10285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC85_10290	COG0719	Fe-S assembly protein
FOC85_10295	COG0396	ATPase activity
FOC85_10300	COG1464	Belongs to the NlpA lipoprotein family
FOC85_10305	COG1464	Belongs to the NlpA lipoprotein family
FOC85_10310	COG2011	ABC-type metal ion transport system permease component
FOC85_10315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC85_10325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC85_10330	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC85_10340	COG1393	Belongs to the ArsC family
FOC85_10385	COG0039	L-malate dehydrogenase activity
FOC85_10410	COG1396	sequence-specific DNA binding
FOC85_10415	COG1309	transcriptional regulator
FOC85_10420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_10430	COG4555	ABC transporter
FOC85_10455	COG1960	acyl-CoA dehydrogenase activity
FOC85_10460	COG0183	Belongs to the thiolase family
FOC85_10465	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC85_10465	COG1024	Enoyl-CoA hydratase
FOC85_10475	COG1686	Belongs to the peptidase S11 family
FOC85_10490	COG0011	TIGRFAM Protein of
FOC85_10495	COG0840	transmembrane signaling receptor activity
FOC85_10515	COG2814	Major facilitator Superfamily
FOC85_10520	COG0531	amino acid
FOC85_10535	COG0706	membrane insertase activity
FOC85_10545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_10580	COG0586	Pfam SNARE associated Golgi protein
FOC85_10590	COG1376	ErfK ybiS ycfS ynhG family protein
FOC85_10595	COG0745	RESPONSE REGULATOR receiver
FOC85_10600	COG5002	protein histidine kinase activity
FOC85_10625	COG0840	transmembrane signaling receptor activity
FOC85_10630	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC85_10635	COG3227	Zinc metalloprotease (Elastase)
FOC85_10640	COG1741	Belongs to the pirin family
FOC85_10655	COG0475	glutathione-regulated potassium exporter activity
FOC85_10660	COG0490	domain, Protein
FOC85_10665	COG1115	amino acid carrier protein
FOC85_10670	COG0783	Belongs to the Dps family
FOC85_10685	COG1611	Belongs to the LOG family
FOC85_10705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC85_10710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC85_10715	COG1115	amino acid carrier protein
FOC85_10720	COG1115	amino acid carrier protein
FOC85_10725	COG2910	NAD(P)H-binding
FOC85_10740	COG0656	L-ascorbic acid biosynthetic process
FOC85_10745	COG2814	Major facilitator Superfamily
FOC85_10750	COG1733	regulation of RNA biosynthetic process
FOC85_10760	COG1252	NADH dehydrogenase
FOC85_10765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC85_10790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC85_10815	COG0488	(ABC) transporter
FOC85_10820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_10875	COG0557	exoribonuclease II activity
FOC85_10880	COG1647	Serine aminopeptidase, S33
FOC85_10885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC85_10890	COG1346	cytolysis
FOC85_10925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC85_10940	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC85_10965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC85_10980	COG2323	membrane
FOC85_10990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC85_11000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC85_11010	COG1051	belongs to the nudix hydrolase family
FOC85_11020	COG0492	ferredoxin-NADP+ reductase activity
FOC85_11025	COG0457	Tetratricopeptide repeat
FOC85_11030	COG0110	maltose O-acetyltransferase activity
FOC85_11050	COG1950	PFAM Membrane protein of
FOC85_11100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC85_11105	COG0556	nucleotide-excision repair
FOC85_11120	COG0789	Transcriptional regulator
FOC85_11145	COG2855	membrane
FOC85_11150	COG0583	DNA-binding transcription factor activity
FOC85_11160	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC85_11165	COG0488	(ABC) transporter
FOC85_11175	COG1132	(ABC) transporter
FOC85_11180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC85_11185	COG0793	Belongs to the peptidase S41A family
FOC85_11185	COG3409	Peptidoglycan-binding domain 1 protein
FOC85_11190	COG2177	Part of the ABC transporter FtsEX involved in
FOC85_11195	COG2884	Cell division ATP-binding protein ftsE
FOC85_11215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC85_11220	COG1278	Cold shock
FOC85_11225	COG1040	competence protein
FOC85_11230	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC85_11235	COG1388	LysM domain
FOC85_11235	COG0791	NLP P60 protein
FOC85_11240	COG1733	regulation of RNA biosynthetic process
FOC85_11245	COG1307	EDD domain protein, DegV family
FOC85_11250	COG1739	Uncharacterized protein family UPF0029
FOC85_11255	COG1316	TRANSCRIPTIONal
FOC85_11260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC85_11265	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC85_11270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC85_11280	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC85_11280	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC85_11300	COG1486	melibiose metabolic process
FOC85_11305	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC85_11310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC85_11320	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC85_11340	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC85_11350	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC85_11355	COG1301	dicarboxylic acid transport
FOC85_11365	COG0346	lactoylglutathione lyase activity
FOC85_11385	COG1511	domain protein
FOC85_11390	COG0583	DNA-binding transcription factor activity
FOC85_11395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC85_11405	COG1271	oxidase subunit
FOC85_11410	COG1294	oxidase, subunit
FOC85_11415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC85_11425	COG1620	l-lactate permease
FOC85_11440	COG2389	metal-binding protein
FOC85_11450	COG1368	sulfuric ester hydrolase activity
FOC85_11460	COG1388	LysM domain
FOC85_11460	COG0791	NLP P60 protein
FOC85_11465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC85_11475	COG1215	transferase activity, transferring glycosyl groups
FOC85_11480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC85_11485	COG1388	LysM domain
FOC85_11485	COG3584	3D domain protein
FOC85_11510	COG4715	Zinc finger, swim domain protein
FOC85_11515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC85_11560	COG0577	efflux transmembrane transporter activity
FOC85_11565	COG1136	(ABC) transporter
FOC85_11605	COG0745	RESPONSE REGULATOR receiver
FOC85_11610	COG1482	cell wall glycoprotein biosynthetic process
FOC85_11615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC85_11615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC85_11615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC85_11620	COG3711	transcriptional antiterminator
FOC85_11620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC85_11625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC85_11640	COG1482	cell wall glycoprotein biosynthetic process
FOC85_11645	COG0662	Cupin 2, conserved barrel domain protein
FOC85_11645	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOC85_11650	COG0438	transferase activity, transferring glycosyl groups
FOC85_11660	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC85_11675	COG2244	polysaccharide biosynthetic process
FOC85_11680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC85_11685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC85_11690	COG4464	protein tyrosine phosphatase activity
FOC85_11695	COG0489	protein tyrosine kinase activity
FOC85_11700	COG3944	biosynthesis protein
FOC85_11705	COG0489	protein tyrosine kinase activity
FOC85_11720	COG1609	Transcriptional regulator
FOC85_11730	COG0739	heme binding
FOC85_11745	COG3279	Response regulator of the LytR AlgR family
FOC85_11750	COG2385	sporulation resulting in formation of a cellular spore
FOC85_11765	COG4836	Membrane
FOC85_11770	COG1007	ATP synthesis coupled electron transport
FOC85_11775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC85_11780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC85_11790	COG0839	Belongs to the complex I subunit 6 family
FOC85_11810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC85_11825	COG5001	Diguanylate cyclase
FOC85_11825	COG3300	MHYT domain
FOC85_11875	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC85_11910	COG0698	ribose 5-phosphate isomerase
FOC85_11920	COG2190	(PTS) system
FOC85_11925	COG2259	Doxx family
FOC85_11930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC85_11945	COG0009	L-threonylcarbamoyladenylate synthase
FOC85_11960	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC85_11980	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC85_11985	COG1494	fructose-1,6-bisphosphatase
FOC85_12005	COG4821	SIS domain
FOC85_12025	COG1960	acyl-CoA dehydrogenase activity
FOC85_12030	COG1960	acyl-CoA dehydrogenase activity
FOC85_12035	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC85_12040	COG0183	Belongs to the thiolase family
FOC85_12045	COG2181	nitrate reductase activity
FOC85_12045	COG0247	lactate metabolic process
FOC85_12050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC85_12060	COG5001	Diguanylate cyclase
FOC85_12060	COG3300	MHYT domain
FOC85_12080	COG2197	response regulator
FOC85_12085	COG4585	Histidine kinase
FOC85_12090	COG0842	Transport permease protein
FOC85_12095	COG1131	(ABC) transporter
FOC85_12100	COG0024	Methionine aminopeptidase
FOC85_12110	COG2234	aminopeptidase activity
FOC85_12130	COG1595	DNA-templated transcription, initiation
FOC85_12140	COG4506	Protein conserved in bacteria
FOC85_12145	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC85_12160	COG0010	Belongs to the arginase family
FOC85_12170	COG2814	Major facilitator Superfamily
FOC85_12175	COG0789	Transcriptional regulator
FOC85_12180	COG0584	glycerophosphoryl diester phosphodiesterase
FOC85_12185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC85_12195	COG1994	Peptidase M50
FOC85_12205	COG1078	dGTPase activity
FOC85_12210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_12215	COG1120	ATPase activity
FOC85_12220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_12225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_12245	COG0095	Lipoate-protein ligase
FOC85_12250	COG0280	phosphate acetyltransferase
FOC85_12265	COG3773	Cell wall hydrolase
FOC85_12275	COG2363	Small membrane protein
FOC85_12285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC85_12290	COG2233	PERMEase
FOC85_12295	COG0561	phosphatase activity
FOC85_12300	COG2814	Major facilitator Superfamily
FOC85_12310	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC85_12315	COG1131	(ABC) transporter
FOC85_12320	COG2755	lipolytic protein G-D-S-L family
FOC85_12325	COG1609	Transcriptional regulator
FOC85_12335	COG0460	homoserine dehydrogenase
FOC85_12345	COG2873	o-acetylhomoserine
FOC85_12350	COG1011	Hydrolase
FOC85_12355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC85_12365	COG2197	response regulator
FOC85_12370	COG4585	Histidine kinase
FOC85_12370	COG2203	Gaf domain
FOC85_12375	COG0351	phosphomethylpyrimidine kinase
FOC85_12380	COG3706	GGDEF domain
FOC85_12385	COG2879	small protein
FOC85_12390	COG1966	Carbon starvation protein
FOC85_12395	COG3279	Response regulator of the LytR AlgR family
FOC85_12400	COG0477	Major facilitator Superfamily
FOC85_12425	COG0840	transmembrane signaling receptor activity
FOC85_12435	COG1607	acyl-coa hydrolase
FOC85_12450	COG0488	(ABC) transporter
FOC85_12470	COG0463	Glycosyl transferase, family 2
FOC85_12475	COG1309	transcriptional regulator
FOC85_12480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC85_12485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC85_12485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC85_12490	COG0628	permease
FOC85_12505	COG3279	Response regulator of the LytR AlgR family
FOC85_12510	COG3275	phosphorelay sensor kinase activity
FOC85_12515	COG2814	Major facilitator Superfamily
FOC85_12520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC85_12525	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC85_12530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC85_12550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC85_12555	COG1272	protein, Hemolysin III
FOC85_12580	COG1164	Oligoendopeptidase f
FOC85_12600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC85_12605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC85_12610	COG4853	Protein conserved in bacteria
FOC85_12615	COG4863	YycH protein
FOC85_12620	COG5002	protein histidine kinase activity
FOC85_12625	COG0745	RESPONSE REGULATOR receiver
FOC85_12655	COG0305	Participates in initiation and elongation during chromosome replication
FOC85_12665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC85_12670	COG4241	membrane
FOC85_12680	COG0629	single-stranded DNA binding
FOC85_12690	COG0012	GTP binding
FOC85_12695	COG4481	Protein conserved in bacteria
FOC85_12700	COG0668	transmembrane transport
FOC85_12710	COG1475	DNA binding
FOC85_12715	COG1192	Involved in chromosome partitioning
FOC85_12740	COG1847	R3H domain protein
FOC85_12745	COG0706	membrane insertase activity
FOC85_12755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC85_12765	COG0592	DNA-directed DNA polymerase activity
FOC85_12770	COG2501	S4 domain
FOC85_12780	COG0187	DNA topoisomerase II activity
FOC85_12785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC85_12820	COG0517	IMP dehydrogenase activity
FOC85_12820	COG0516	GMP reductase activity
FOC85_12825	COG1686	Belongs to the peptidase S11 family
FOC85_12855	COG1428	Deoxynucleoside kinase
FOC85_12860	COG1428	Deoxynucleoside kinase
FOC85_12865	COG1335	isochorismatase
FOC85_12870	COG0590	tRNA wobble adenosine to inosine editing
FOC85_12880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC85_12935	COG1982	Orn Lys Arg decarboxylase major
FOC85_12945	COG0470	DNA polymerase III
FOC85_12950	COG1774	PSP1 C-terminal conserved region
FOC85_12960	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC85_12970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC85_12975	COG2002	toxin-antitoxin pair type II binding
FOC85_12980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC85_12980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC85_12985	COG0084	hydrolase, TatD family'
FOC85_12990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC85_13005	COG4466	Protein conserved in bacteria
FOC85_13020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC85_13025	COG0251	oxidation-reduction process
FOC85_13055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC85_13060	COG2002	toxin-antitoxin pair type II binding
FOC85_13065	COG2244	polysaccharide biosynthetic process
FOC85_13070	COG3956	TIGRFAM MazG family protein
FOC85_13075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC85_13095	COG1098	S1 RNA binding domain
FOC85_13110	COG2208	phosphoserine phosphatase activity
FOC85_13125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC85_13140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC85_13145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC85_13150	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC85_13155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC85_13160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC85_13165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC85_13170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC85_13175	COG1396	sequence-specific DNA binding
FOC85_13180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC85_13270	COG3880	PFAM UvrB UvrC protein
FOC85_13280	COG0542	response to heat
FOC85_13285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC85_13295	COG4956	integral membrane protein (PIN domain superfamily)
FOC85_13315	COG1045	serine acetyltransferase
FOC85_13330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC85_13335	COG3688	RNA-binding protein containing a PIN domain
FOC85_13350	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC85_13355	COG0250	Participates in transcription elongation, termination and antitermination
FOC85_13360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC85_13380	COG2813	Specifically methylates the guanine in position
FOC85_13395	COG1358	cellular component organization or biogenesis
FOC85_13465	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC85_13525	COG0201	protein transport
FOC85_13535	COG0024	Methionine aminopeptidase
FOC85_13545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC85_13580	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC85_13605	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC85_13610	COG0489	protein tyrosine kinase activity
FOC85_13620	COG2194	sulfuric ester hydrolase activity
FOC85_13625	COG0726	polysaccharide deacetylase
FOC85_13705	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC85_13710	COG4856	YbbR-like protein
FOC85_13755	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC85_13760	COG1506	peptidase
FOC85_13760	COG0823	Involved in the tonB-independent uptake of proteins
FOC85_13760	COG4946	Tricorn protease homolog
FOC85_13800	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_13805	COG2011	ABC-type metal ion transport system permease component
FOC85_13810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC85_13815	COG1464	Belongs to the NlpA lipoprotein family
FOC85_13820	COG0604	alcohol dehydrogenase
FOC85_13830	COG0277	FAD linked oxidase domain protein
FOC85_13835	COG2271	Major facilitator Superfamily
FOC85_13845	COG2814	Major facilitator Superfamily
FOC85_13860	COG0601	transmembrane transport
FOC85_13865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC85_13870	COG0444	Belongs to the ABC transporter superfamily
FOC85_13875	COG4608	Belongs to the ABC transporter superfamily
FOC85_13880	COG4166	transmembrane transport
FOC85_13890	COG2207	Transcriptional regulator
FOC85_13900	COG1309	transcriptional regulator
FOC85_13910	COG4166	transmembrane transport
FOC85_13915	COG4166	transmembrane transport
FOC85_13920	COG0656	L-ascorbic acid biosynthetic process
FOC85_13925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC85_13940	COG4149	molybdate abc transporter
FOC85_13945	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC85_13950	COG1910	domain protein
FOC85_13965	COG0697	spore germination
FOC85_13980	COG0204	Acyl-transferase
FOC85_13990	COG1609	Transcriptional regulator
FOC85_14000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_14010	COG0084	hydrolase, TatD family'
FOC85_14020	COG5298	Protein conserved in bacteria
FOC85_14045	COG0488	(ABC) transporter
FOC85_14060	COG0747	negative chemotaxis
FOC85_14065	COG0601	transmembrane transport
FOC85_14075	COG0444	Belongs to the ABC transporter superfamily
FOC85_14080	COG4608	Belongs to the ABC transporter superfamily
FOC85_14085	COG0561	phosphatase activity
FOC85_14115	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC85_14120	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC85_14130	COG0531	amino acid
FOC85_14135	COG2814	Major facilitator Superfamily
FOC85_14145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC85_14155	COG4294	response to UV
FOC85_14160	COG0705	Rhomboid family
FOC85_14160	COG0457	Tetratricopeptide repeat
FOC85_14170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC85_14175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC85_14180	COG0864	Transcriptional regulator
FOC85_14185	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC85_14190	COG2183	response to ionizing radiation
FOC85_14285	COG0802	atpase or kinase
FOC85_14290	COG1214	PFAM Peptidase M22, glycoprotease
FOC85_14295	COG0456	acetyltransferase
FOC85_14305	COG0488	(ABC) transporter
FOC85_14320	COG1266	CAAX protease self-immunity
FOC85_14335	COG5444	nuclease activity
FOC85_14355	COG0582	viral genome integration into host DNA
FOC85_14395	COG2252	PERMEase
FOC85_14405	COG5002	protein histidine kinase activity
FOC85_14430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC85_14500	COG2205	protein histidine kinase activity
FOC85_14505	COG0745	RESPONSE REGULATOR receiver
FOC85_14525	COG0697	spore germination
FOC85_14550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC85_14555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC85_14560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC85_14570	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC85_14585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC85_14595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC85_14605	COG0151	Belongs to the GarS family
FOC85_14630	COG0210	DNA helicase
FOC85_14640	COG4851	CamS sex pheromone cAM373 precursor
FOC85_14660	COG1335	isochorismatase
FOC85_14665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC85_14670	COG2011	ABC-type metal ion transport system permease component
FOC85_14675	COG1464	Belongs to the NlpA lipoprotein family
FOC85_14700	COG0003	Pfam Anion-transporting ATPase
FOC85_14705	COG1846	Transcriptional regulator
FOC85_14710	COG4682	membrane
FOC85_14730	COG1597	lipid kinase activity
FOC85_14735	COG0546	phosphoglycolate phosphatase activity
FOC85_14740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC85_14750	COG1012	belongs to the aldehyde dehydrogenase family
FOC85_14755	COG2076	Multidrug Resistance protein
FOC85_14760	COG2309	aminopeptidase activity
FOC85_14775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC85_14780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC85_14785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC85_14790	COG5002	protein histidine kinase activity
FOC85_14795	COG4807	Protein conserved in bacteria
FOC85_14825	COG1473	amidohydrolase
FOC85_14840	COG0450	alkyl hydroperoxide reductase
FOC85_14860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_14865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_14870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_14885	COG0166	Belongs to the GPI family
FOC85_14915	COG5002	protein histidine kinase activity
FOC85_14935	COG3541	Predicted nucleotidyltransferase
FOC85_14940	COG2814	Major facilitator Superfamily
FOC85_14945	COG0723	plastoquinol--plastocyanin reductase activity
FOC85_14945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC85_14955	COG0765	amino acid transport
FOC85_14960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC85_14970	COG0840	transmembrane signaling receptor activity
FOC85_14995	COG0549	Belongs to the carbamate kinase family
FOC85_15015	COG0366	Alpha amylase catalytic
FOC85_15020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC85_15020	COG2190	(PTS) system
FOC85_15020	COG1263	PTS System
FOC85_15050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC85_15065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC85_15075	COG1116	anion transmembrane transporter activity
FOC85_15130	COG2270	Major facilitator Superfamily
FOC85_15160	COG2310	stress, protein
FOC85_15165	COG2310	stress, protein
FOC85_15170	COG2310	stress, protein
FOC85_15175	COG0861	Integral membrane protein TerC family
FOC85_15185	COG3853	Toxic anion resistance protein (TelA)
FOC85_15200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC85_15210	COG1295	ribonuclease BN
FOC85_15215	COG2217	Heavy metal translocating P-type atpase
FOC85_15220	COG0697	spore germination
FOC85_15240	COG0586	Pfam SNARE associated Golgi protein
FOC85_15255	COG3871	stress protein (general stress protein 26)
FOC85_15260	COG0387	Pfam Sodium calcium exchanger
FOC85_15270	COG0535	radical SAM domain protein
FOC85_15290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC85_15310	COG3829	transcription factor binding
FOC85_15320	COG0833	amino acid
FOC85_15325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC85_15355	COG1263	PTS System
FOC85_15355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC85_15360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC85_15375	COG0463	Glycosyl transferase, family 2
FOC85_15385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC85_15385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC85_15405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC85_15425	COG1228	amidohydrolase
FOC85_15430	COG1090	epimerase
FOC85_15460	COG1988	membrane-bound metal-dependent
FOC85_15465	COG1194	a g-specific adenine glycosylase
FOC85_15490	COG1132	(ABC) transporter
FOC85_15495	COG4129	membrane
FOC85_15500	COG0070	glutamate synthase
FOC85_15500	COG0067	glutamate synthase
FOC85_15500	COG0069	glutamate synthase activity
FOC85_15510	COG4555	ABC transporter
FOC85_15530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC85_15535	COG0735	belongs to the Fur family
FOC85_15670	COG1132	(ABC) transporter
FOC85_15685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC85_15690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC85_15705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC85_15715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC85_15720	COG1716	ATPase activity
FOC85_15720	COG5001	Diguanylate cyclase
FOC85_15725	COG2766	serine protein kinase
FOC85_15745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC85_15755	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC85_15760	COG2268	Band 7 protein
FOC85_15770	COG3290	protein histidine kinase activity
FOC85_15775	COG4565	transcriptional regulatory protein
FOC85_15780	COG2851	Citrate transporter
FOC85_15800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC85_15805	COG3842	ATPase activity
FOC85_15810	COG1175	transmembrane transport
FOC85_15815	COG0395	ABC-type sugar transport system, permease component
FOC85_15825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC85_15830	COG0745	RESPONSE REGULATOR receiver
FOC85_15835	COG5002	protein histidine kinase activity
FOC85_15845	COG4990	cell redox homeostasis
FOC85_15855	COG3290	protein histidine kinase activity
FOC85_15860	COG4565	transcriptional regulatory protein
FOC85_15865	COG3493	citrate carrier protein
FOC85_15870	COG0281	malic enzyme
FOC85_15885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_15895	COG5002	protein histidine kinase activity
FOC85_15900	COG0745	RESPONSE REGULATOR receiver
FOC85_15905	COG0454	-acetyltransferase
FOC85_15905	COG0456	acetyltransferase
FOC85_15910	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC85_15915	COG3383	formate dehydrogenase (NAD+) activity
FOC85_15920	COG2427	Protein of unknown function (DUF1641)
FOC85_15935	COG0531	amino acid
FOC85_15940	COG0640	Transcriptional regulator
FOC85_15945	COG2217	Heavy metal translocating P-type atpase
FOC85_15950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC85_15965	COG3227	Zinc metalloprotease (Elastase)
FOC85_15985	COG2720	vancomycin resistance protein
FOC85_15990	COG1316	TRANSCRIPTIONal
FOC85_15995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC85_16000	COG0346	lactoylglutathione lyase activity
FOC85_16005	COG1253	flavin adenine dinucleotide binding
FOC85_16010	COG1027	Aspartate ammonia-lyase
FOC85_16015	COG1620	l-lactate permease
FOC85_16030	COG3104	oligopeptide transport
FOC85_16035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_16045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC85_16055	COG2226	methyltransferase
FOC85_16060	COG0156	8-amino-7-oxononanoate synthase activity
FOC85_16065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC85_16075	COG4548	von Willebrand factor, type A
FOC85_16080	COG0714	Associated with various cellular activities
FOC85_16085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC85_16100	COG0531	amino acid
FOC85_16105	COG2188	Transcriptional regulator
FOC85_16110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC85_16110	COG1263	PTS System
FOC85_16115	COG0366	Alpha amylase catalytic
FOC85_16130	COG0697	spore germination
FOC85_16135	COG4585	Histidine kinase
FOC85_16140	COG2197	response regulator
FOC85_16145	COG1404	Belongs to the peptidase S8 family
FOC85_16160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC85_16165	COG1115	amino acid carrier protein
FOC85_16170	COG1126	abc transporter atp-binding protein
FOC85_16175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC85_16180	COG0765	amino acid transport
FOC85_16185	COG0765	amino acid transport
FOC85_16190	COG0833	amino acid
FOC85_16215	COG2378	regulation of single-species biofilm formation
FOC85_16220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC85_16225	COG5002	protein histidine kinase activity
FOC85_16240	COG0659	secondary active sulfate transmembrane transporter activity
FOC85_16255	COG0747	negative chemotaxis
FOC85_16265	COG0601	transmembrane transport
FOC85_16270	COG4608	Belongs to the ABC transporter superfamily
FOC85_16280	COG2271	Major facilitator Superfamily
FOC85_16285	COG1846	Transcriptional regulator
FOC85_16290	COG0477	Major facilitator Superfamily
FOC85_16295	COG1609	Transcriptional regulator
FOC85_16300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC85_16315	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC85_16320	COG1879	ABC-type sugar transport system periplasmic component
FOC85_16340	COG1063	alcohol dehydrogenase
FOC85_16355	COG3568	Endonuclease Exonuclease Phosphatase
FOC85_16385	COG0840	transmembrane signaling receptor activity
FOC85_16390	COG3584	3D domain protein
FOC85_16390	COG1388	LysM domain
FOC85_16395	COG1476	TRANSCRIPTIONal
FOC85_16410	COG3104	oligopeptide transport
FOC85_16415	COG1114	Component of the transport system for branched-chain amino acids
FOC85_16430	COG1113	amino acid transport
FOC85_16435	COG2252	PERMEase
FOC85_16450	COG2153	protein acetylation
FOC85_16460	COG0569	domain protein
FOC85_16460	COG0475	glutathione-regulated potassium exporter activity
FOC85_16475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC85_16480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC85_16485	COG4990	cell redox homeostasis
FOC85_16500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC85_16505	COG0697	spore germination
FOC85_16510	COG0531	amino acid
FOC85_16520	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC85_16525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC85_16530	COG1918	ferrous iron import across plasma membrane
FOC85_16530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC85_16535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC85_16540	COG0573	inorganic phosphate transmembrane transporter activity
FOC85_16545	COG0581	inorganic phosphate transmembrane transporter activity
FOC85_16555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC85_16675	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC85_16695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC85_16700	COG1116	anion transmembrane transporter activity
FOC85_16705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC85_16710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC85_16715	COG0352	thiamine-phosphate diphosphorylase activity
FOC85_16720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC85_16725	COG2104	thiamine diphosphate biosynthetic process
FOC85_16735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC85_16740	COG0351	phosphomethylpyrimidine kinase
FOC85_16780	COG2205	protein histidine kinase activity
FOC85_16785	COG2814	Major facilitator Superfamily
FOC85_16790	COG1846	Transcriptional regulator
FOC85_16815	COG1136	(ABC) transporter
FOC85_16815	COG0577	efflux transmembrane transporter activity
FOC85_16825	COG2252	PERMEase
FOC85_16830	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC85_16850	COG1621	beta-fructofuranosidase activity
FOC85_16855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC85_16855	COG1263	PTS System
FOC85_16860	COG1609	Transcriptional regulator
FOC85_16870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC85_16910	COG0778	Nitroreductase
FOC85_16915	COG2719	SpoVR family
FOC85_16920	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC85_16925	COG1937	Protein conserved in bacteria
FOC85_16930	COG0425	Belongs to the sulfur carrier protein TusA family
FOC85_16930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC85_16935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC85_16935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_16940	COG0425	Belongs to the sulfur carrier protein TusA family
FOC85_16945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC85_16955	COG2210	Belongs to the sulfur carrier protein TusA family
FOC85_16960	COG0730	response to heat
FOC85_16970	COG1316	TRANSCRIPTIONal
FOC85_16975	COG0604	alcohol dehydrogenase
FOC85_16980	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC85_16995	COG3711	transcriptional antiterminator
FOC85_16995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC85_17000	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC85_17005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC85_17025	COG3584	3D domain protein
FOC85_17025	COG1388	LysM domain
FOC85_17030	COG0577	efflux transmembrane transporter activity
FOC85_17035	COG1136	(ABC) transporter
FOC85_17045	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC85_17060	COG0577	efflux transmembrane transporter activity
FOC85_17065	COG1114	Component of the transport system for branched-chain amino acids
FOC85_17070	COG3546	catalase activity
FOC85_17105	COG0586	Pfam SNARE associated Golgi protein
FOC85_17140	COG0531	amino acid
FOC85_17145	COG0475	glutathione-regulated potassium exporter activity
FOC85_17155	COG1737	Transcriptional regulator
FOC85_17165	COG1263	PTS System
FOC85_17165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC85_17180	COG2259	Doxx family
FOC85_17200	COG1522	sequence-specific DNA binding
FOC85_17215	COG2076	Multidrug Resistance protein
FOC85_17220	COG1309	transcriptional regulator
FOC85_17225	COG2814	Major facilitator Superfamily
FOC85_17230	COG4533	DNA binding
FOC85_17235	COG2211	Major facilitator Superfamily
FOC85_17245	COG0693	protein deglycase activity
FOC85_17250	COG0753	catalase activity
FOC85_17250	COG0693	protein deglycase activity
FOC85_17260	COG0531	amino acid
FOC85_17275	COG1012	belongs to the aldehyde dehydrogenase family
FOC85_17280	COG1132	(ABC) transporter
FOC85_17285	COG1132	(ABC) transporter
FOC85_17290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC85_17295	COG0765	amino acid transport
FOC85_17300	COG1126	abc transporter atp-binding protein
FOC85_17315	COG0189	ligase activity
FOC85_17345	COG0028	Belongs to the TPP enzyme family
FOC85_17350	COG3527	Alpha-acetolactate decarboxylase
FOC85_17360	COG0561	phosphatase activity
FOC85_17365	COG3409	Peptidoglycan-binding domain 1 protein
FOC85_17365	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC85_17370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC85_17385	COG0659	secondary active sulfate transmembrane transporter activity
FOC85_17415	COG2244	polysaccharide biosynthetic process
FOC85_17425	COG4196	transglutaminase domain protein
FOC85_17430	COG4196	transglutaminase domain protein
FOC85_17450	COG1024	Enoyl-CoA hydratase
FOC85_17470	COG1363	Peptidase, m42
FOC85_17490	COG3938	Belongs to the proline racemase family
FOC85_17510	COG0601	transmembrane transport
FOC85_17515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC85_17520	COG0444	Belongs to the ABC transporter superfamily
FOC85_17525	COG4608	Belongs to the ABC transporter superfamily
FOC85_17570	COG0477	Major facilitator Superfamily
FOC85_17575	COG3290	protein histidine kinase activity
FOC85_17580	COG4565	transcriptional regulatory protein
FOC85_17585	COG3181	Tripartite tricarboxylate transporter family receptor
FOC85_17640	COG0305	Participates in initiation and elongation during chromosome replication
FOC85_17660	COG0477	Major facilitator Superfamily
FOC85_17720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC85_17720	COG3320	Male sterility
FOC85_17725	COG1309	transcriptional regulator
FOC85_17740	COG1183	phosphatidylcholine synthase activity
FOC85_17770	COG2376	Dihydroxyacetone kinase
FOC85_17780	COG2376	Dihydroxyacetone kinase
FOC85_17785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC85_17790	COG1959	2 iron, 2 sulfur cluster binding
FOC85_17805	COG0457	Tetratricopeptide repeat
FOC85_17815	COG3437	response regulator, receiver
FOC85_17815	COG2770	Histidine kinase
FOC85_17890	COG1191	sigma factor activity
FOC85_17900	COG2208	phosphoserine phosphatase activity
FOC85_17905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC85_17910	COG2205	protein histidine kinase activity
FOC85_17910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC85_17910	COG0784	Response regulator, receiver
FOC85_17910	COG2198	Histidine kinase
FOC85_17950	COG4585	Histidine kinase
FOC85_17955	COG2197	response regulator
FOC85_17985	COG0420	3'-5' exonuclease activity
FOC85_17990	COG4717	serine-type aminopeptidase activity
FOC85_18020	COG0346	lactoylglutathione lyase activity
FOC85_18025	COG0346	lactoylglutathione lyase activity
FOC85_18030	COG0457	Tetratricopeptide repeat
FOC85_18040	COG2267	carboxylic ester hydrolase activity
FOC85_18060	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC85_18065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC85_18075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC85_18120	COG0477	Major facilitator Superfamily
FOC85_18125	COG0477	Major facilitator Superfamily
FOC85_18135	COG3973	AAA domain
FOC85_18140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC85_18160	COG4980	gas vesicle protein
FOC85_18165	COG0537	adenosine 5'-monophosphoramidase activity
FOC85_18170	COG1131	(ABC) transporter
FOC85_18175	COG4473	ABC transporter
FOC85_18190	COG1309	transcriptional regulator
FOC85_18200	COG3402	PFAM membrane-flanked domain
FOC85_18205	COG3428	Bacterial PH domain
FOC85_18225	COG1309	transcriptional regulator
FOC85_18245	COG3402	PFAM membrane-flanked domain
FOC85_18250	COG3428	Bacterial PH domain
FOC85_18255	COG2329	Antibiotic biosynthesis monooxygenase
FOC85_18260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC85_18315	COG1309	transcriptional regulator
FOC85_18320	COG1511	domain protein
FOC85_18325	COG1511	domain protein
FOC85_18355	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOC85_18365	COG2378	regulation of single-species biofilm formation
FOC85_18370	COG1609	Transcriptional regulator
FOC85_18380	COG1234	tRNA 3'-trailer cleavage
FOC85_18385	COG0095	Lipoate-protein ligase
FOC85_18395	COG0318	PFAM AMP-dependent synthetase and ligase
FOC85_18460	COG1073	alpha beta
FOC85_18465	COG1408	metallophosphoesterase
FOC85_18475	COG1078	dGTPase activity
FOC85_18485	COG1595	DNA-templated transcription, initiation
FOC85_18490	COG2207	Transcriptional regulator
FOC85_18490	COG3708	Transcriptional regulator
FOC85_18495	COG2205	protein histidine kinase activity
FOC85_18500	COG0745	RESPONSE REGULATOR receiver
FOC85_18520	COG0501	Belongs to the peptidase M48B family
FOC85_18525	COG0697	spore germination
FOC85_18545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC85_18550	COG2224	Isocitrate lyase
FOC85_18575	COG4903	ComK protein
FOC85_18580	COG0398	Pfam SNARE associated Golgi protein
FOC85_18640	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC85_18665	COG0367	asparagine synthase
FOC85_18675	COG0753	catalase activity
FOC85_18680	COG0004	ammonium transporteR
FOC85_18700	COG2996	Protein conserved in bacteria
FOC85_18710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC85_18720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_18735	COG0561	phosphatase activity
FOC85_18745	COG0542	response to heat
FOC85_18755	COG2267	carboxylic ester hydrolase activity
FOC85_18770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC85_18775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC85_18780	COG5504	Zn-dependent protease
FOC85_18790	COG0180	Tryptophanyl-tRNA synthetase
FOC85_18800	COG4166	transmembrane transport
FOC85_18805	COG0601	transmembrane transport
FOC85_18810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC85_18815	COG0444	Belongs to the ABC transporter superfamily
FOC85_18820	COG4608	Belongs to the ABC transporter superfamily
FOC85_18825	COG0534	Mate efflux family protein
FOC85_18830	COG4166	transmembrane transport
FOC85_18845	COG0861	Integral membrane protein TerC family
FOC85_18850	COG4862	establishment of competence for transformation
FOC85_18855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC85_18865	COG1164	Oligoendopeptidase f
FOC85_18880	COG2346	COG2346, Truncated hemoglobins
FOC85_18885	COG4116	CYTH
FOC85_18895	COG2357	RelA SpoT domain protein
FOC85_18905	COG0564	pseudouridine synthase activity
FOC85_18920	COG0772	Belongs to the SEDS family
FOC85_18925	COG1216	Glycosyl transferase, family 2
FOC85_18945	COG0463	Glycosyl transferase, family 2
FOC85_18945	COG0457	Tetratricopeptide repeat
FOC85_18965	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC85_18980	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC85_19025	COG2153	protein acetylation
FOC85_19035	COG2382	esterase
FOC85_19050	COG5492	domain, Protein
FOC85_19055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC85_19065	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC85_19065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC85_19100	COG1620	l-lactate permease
FOC85_19105	COG5634	Uncharacterized conserved protein (DUF2278)
FOC85_19160	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC85_19170	COG1476	TRANSCRIPTIONal
FOC85_19230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC85_19245	COG4152	abc transporter atp-binding protein
FOC85_19250	COG1668	transmembrane transport
FOC85_19310	COG2226	methyltransferase
FOC85_19320	COG1686	Belongs to the peptidase S11 family
FOC85_19325	COG0681	Belongs to the peptidase S26 family
FOC85_19360	COG1012	belongs to the aldehyde dehydrogenase family
FOC85_19370	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC85_19375	COG1177	transmembrane transport
FOC85_19380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC85_19390	COG2409	Drug exporters of the RND superfamily
FOC85_19400	COG0564	pseudouridine synthase activity
FOC85_19410	COG2340	Cysteine-rich secretory protein family
FOC85_19415	COG0247	lactate metabolic process
FOC85_19420	COG0277	FAD linked oxidase domain protein
FOC85_19425	COG3835	regulator
FOC85_19435	COG0745	RESPONSE REGULATOR receiver
FOC85_19440	COG5002	protein histidine kinase activity
FOC85_19445	COG2186	Transcriptional regulator
FOC85_19465	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC85_19475	COG2116	formate transmembrane transporter activity
FOC85_19480	COG0861	Integral membrane protein TerC family
FOC85_19485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC85_19495	COG2030	dehydratase
FOC85_19515	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_19520	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC85_19530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC85_19545	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC85_19550	COG3842	ATPase activity
FOC85_19575	COG1349	DNA-binding transcription factor activity
FOC85_19585	COG0235	Class ii aldolase
FOC85_19595	COG2861	carbohydrate metabolic process
FOC85_19605	COG3852	Histidine kinase
FOC85_19610	COG1846	Transcriptional regulator
FOC85_19620	COG2318	DinB family
FOC85_19625	COG5002	protein histidine kinase activity
FOC85_19635	COG0720	synthase
FOC85_19650	COG4873	Protein conserved in bacteria
FOC85_19680	COG1780	Probably involved in ribonucleotide reductase function
FOC85_19685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC85_19690	COG1403	HNH endonuclease
FOC85_19700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC85_19705	COG1725	Transcriptional regulator
FOC85_19710	COG1131	(ABC) transporter
FOC85_19720	COG1131	(ABC) transporter
FOC85_19725	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC85_19740	COG1522	sequence-specific DNA binding
FOC85_19750	COG1335	isochorismatase
FOC85_19760	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC85_19765	COG2070	2-Nitropropane dioxygenase
FOC85_19770	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC85_19780	COG1696	Membrane protein involved in D-alanine export
FOC85_19805	COG0716	FMN binding
FOC85_19820	COG3173	Aminoglycoside phosphotransferase
FOC85_19840	COG0534	Mate efflux family protein
FOC85_19845	COG1968	undecaprenyl-diphosphatase activity
FOC85_19860	COG1846	Transcriptional regulator
FOC85_19870	COG1301	dicarboxylic acid transport
FOC85_19875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC85_19880	COG4709	membrane
FOC85_19885	COG3874	Sporulation protein YtfJ
FOC85_19910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC85_19915	COG0028	Belongs to the TPP enzyme family
FOC85_19920	COG0440	acetolactate synthase activity
FOC85_19995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC85_20005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC85_20010	COG1183	phosphatidylcholine synthase activity
FOC85_20015	COG1368	sulfuric ester hydrolase activity
FOC85_20025	COG0019	diaminopimelate decarboxylase activity
FOC85_20045	COG0529	Catalyzes the synthesis of activated sulfate
FOC85_20050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC85_20070	COG1648	precorrin-2 dehydrogenase activity
FOC85_20075	COG0733	neurotransmitter:sodium symporter activity
FOC85_20095	COG1757	Na H antiporter
FOC85_20110	COG4758	membrane
FOC85_20115	COG4585	Histidine kinase
FOC85_20120	COG2197	response regulator
FOC85_20130	COG1114	Component of the transport system for branched-chain amino acids
FOC85_20140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC85_20180	COG0730	response to heat
FOC85_20185	COG0306	phosphate transporter
FOC85_20190	COG1392	Phosphate transport regulator
FOC85_20195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC85_20210	COG3852	Histidine kinase
FOC85_20215	COG1801	Protein of unknown function DUF72
FOC85_20225	COG0582	viral genome integration into host DNA
FOC85_20230	COG5002	protein histidine kinase activity
FOC85_20245	COG0392	lysyltransferase activity
FOC85_20245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC85_20260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC85_20265	COG1686	Belongs to the peptidase S11 family
FOC85_20270	COG2715	membrane protein required for spore maturation
FOC85_20275	COG0700	Nucleoside recognition
FOC85_20280	COG1187	pseudouridine synthase activity
FOC85_20290	COG1333	cytochrome c biogenesis protein
FOC85_20295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC85_20300	COG0745	RESPONSE REGULATOR receiver
FOC85_20305	COG5002	protein histidine kinase activity
FOC85_20310	COG2096	Adenosyltransferase
FOC85_20315	COG4942	peptidase
FOC85_20325	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC85_20330	COG1141	Ferredoxin
FOC85_20340	COG0514	ATP-dependent DNA helicase (RecQ)
FOC85_20345	COG1266	CAAX protease self-immunity
FOC85_20355	COG1408	metallophosphoesterase
FOC85_20365	COG4862	establishment of competence for transformation
FOC85_20370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC85_20390	COG0492	ferredoxin-NADP+ reductase activity
FOC85_20465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC85_20480	COG0142	geranyltranstransferase activity
FOC85_20490	COG0142	geranyltranstransferase activity
FOC85_20510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC85_20515	COG0457	Tetratricopeptide repeat
FOC85_20535	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC85_20545	COG4347	Protein of unknown function (DUF1405)
FOC85_20560	COG2738	Putative neutral zinc metallopeptidase
FOC85_20570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_20575	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC85_20590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC85_20595	COG0438	transferase activity, transferring glycosyl groups
FOC85_20630	COG1199	ATP-dependent helicase activity
FOC85_20630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC85_20650	COG3935	DnaD domain protein
FOC85_20655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC85_20665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC85_20665	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC85_20725	COG0116	Belongs to the methyltransferase superfamily
FOC85_20735	COG1199	ATP-dependent helicase activity
FOC85_20740	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC85_20750	COG3173	Aminoglycoside phosphotransferase
FOC85_20755	COG0024	Methionine aminopeptidase
FOC85_20765	COG2233	PERMEase
FOC85_20770	COG2311	Membrane
FOC85_20775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC85_20785	COG0456	acetyltransferase
FOC85_20820	COG0754	glutathionylspermidine amidase activity
FOC85_20835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC85_20850	COG0454	-acetyltransferase
FOC85_20870	COG0328	RNA-DNA hybrid ribonuclease activity
FOC85_20905	COG3403	YqcI/YcgG family
FOC85_20910	COG1280	lysine exporter protein (LysE YggA)
FOC85_20925	COG3162	membrane
FOC85_20930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC85_20935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC85_20945	COG0475	glutathione-regulated potassium exporter activity
FOC85_20950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC85_20955	COG0789	Transcriptional regulator
FOC85_20955	COG4978	Transcriptional regulator
FOC85_20965	COG2323	membrane
FOC85_20970	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC85_21025	COG1923	regulation of RNA biosynthetic process
FOC85_21035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC85_21040	COG1360	Flagellar Motor Protein
FOC85_21045	COG2201	protein-glutamate methylesterase activity
FOC85_21050	COG0643	Histidine kinase
FOC85_21050	COG2198	Histidine kinase
FOC85_21055	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC85_21055	COG1776	CheC inhibitor of MCP methylation
FOC85_21070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC85_21090	COG1256	bacterial-type flagellum assembly
FOC85_21095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC85_21100	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOC85_21115	COG1815	bacterial-type flagellum-dependent cell motility
FOC85_21120	COG1558	bacterial-type flagellum-dependent cell motility
FOC85_21130	COG1766	The M ring may be actively involved in energy transduction
FOC85_21135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC85_21145	COG1157	protein secretion by the type III secretion system
FOC85_21180	COG0784	Response regulator, receiver
FOC85_21180	COG0835	chemotaxis
FOC85_21190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC85_21195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC85_21200	COG0741	lytic transglycosylase activity
FOC85_21210	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC85_21215	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC85_21215	COG1776	CheC inhibitor of MCP methylation
FOC85_21225	COG1338	Plays a role in the flagellum-specific transport system
FOC85_21230	COG1987	bacterial-type flagellum assembly
FOC85_21240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC85_21245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC85_21250	COG1419	protein localization to endoplasmic reticulum
FOC85_21255	COG4786	Flagellar basal body rod
FOC85_21260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC85_21315	COG2329	Antibiotic biosynthesis monooxygenase
FOC85_21340	COG0583	DNA-binding transcription factor activity
FOC85_21345	COG3842	ATPase activity
FOC85_21360	COG1234	tRNA 3'-trailer cleavage
FOC85_21400	COG0406	alpha-ribazole phosphatase activity
FOC85_21420	COG1846	Transcriptional regulator
FOC85_21430	COG0367	asparagine synthase
FOC85_21460	COG1802	Transcriptional regulator
FOC85_21465	COG0697	spore germination
FOC85_21470	COG0523	cobalamin synthesis protein
FOC85_21475	COG0701	Predicted permease
FOC85_21490	COG1757	Na H antiporter
FOC85_21495	COG0114	fumarate hydratase activity
FOC85_21510	COG0534	Mate efflux family protein
FOC85_21515	COG3340	Belongs to the peptidase S51 family
FOC85_21535	COG0785	Cytochrome C biogenesis protein
FOC85_21565	COG2733	membrane
FOC85_21600	COG1131	(ABC) transporter
FOC85_21615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC85_21620	COG0528	UMP kinase activity
FOC85_21630	COG1027	Aspartate ammonia-lyase
FOC85_21635	COG0281	malic enzyme
FOC85_21640	COG4191	Histidine kinase
FOC85_21645	COG0784	Response regulator, receiver
FOC85_21650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC85_21670	COG3620	sequence-specific DNA binding
FOC85_21695	COG1051	belongs to the nudix hydrolase family
FOC85_21720	COG1966	Carbon starvation protein
FOC85_21730	COG0477	Major facilitator Superfamily
FOC85_21735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC85_21745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC85_21750	COG4166	transmembrane transport
FOC85_21755	COG2223	nitrite transmembrane transporter activity
FOC85_21760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC85_21775	COG2244	polysaccharide biosynthetic process
FOC85_21780	COG0733	neurotransmitter:sodium symporter activity
FOC85_21790	COG5566	PFAM Mor transcription activator
FOC85_21795	COG2323	membrane
FOC85_21815	COG2084	Dehydrogenase
FOC85_21830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC85_21840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC85_21845	COG0028	Belongs to the TPP enzyme family
FOC85_21855	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC85_21865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC85_21890	COG2814	Major facilitator Superfamily
FOC85_21895	COG3384	dioxygenase
FOC85_21915	COG3279	Response regulator of the LytR AlgR family
FOC85_21920	COG0427	acetyl-CoA hydrolase
FOC85_21955	COG4166	transmembrane transport
FOC85_21980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_21985	COG0745	RESPONSE REGULATOR receiver
FOC85_22005	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC85_22020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC85_22025	COG0531	amino acid
FOC85_22070	COG0745	RESPONSE REGULATOR receiver
FOC85_22075	COG2205	protein histidine kinase activity
FOC85_22080	COG2390	Transcriptional regulator
FOC85_22090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC85_22095	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC85_22105	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC85_22125	COG0006	proline dipeptidase activity
FOC85_22130	COG2132	Multicopper oxidase
FOC85_22165	COG1114	Component of the transport system for branched-chain amino acids
FOC85_22175	COG2372	response to copper ion
FOC85_22175	COG1276	copper resistance
FOC85_22180	COG4549	nuclear export factor GLE1
FOC85_22185	COG0697	spore germination
FOC85_22190	COG0583	DNA-binding transcription factor activity
FOC85_22195	COG1959	2 iron, 2 sulfur cluster binding
FOC85_22200	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC85_22205	COG0778	Nitroreductase
FOC85_22215	COG0628	permease
FOC85_22225	COG1231	oxidoreductase activity
FOC85_22230	COG0523	cobalamin synthesis protein
FOC85_22245	COG0318	PFAM AMP-dependent synthetase and ligase
FOC85_22250	COG2030	dehydratase
FOC85_22255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC85_22265	COG0411	ABC transporter
FOC85_22285	COG0583	DNA-binding transcription factor activity
FOC85_22295	COG1942	4-Oxalocrotonate Tautomerase
FOC85_22315	COG1271	oxidase subunit
FOC85_22320	COG1294	oxidase, subunit
FOC85_22325	COG4988	ABC transporter
FOC85_22330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC85_22350	COG1686	Belongs to the peptidase S11 family
FOC85_22365	COG1388	LysM domain
FOC85_22365	COG0791	NLP P60 protein
FOC85_22375	COG1132	(ABC) transporter
FOC85_22380	COG0745	RESPONSE REGULATOR receiver
FOC85_22385	COG2205	protein histidine kinase activity
FOC85_22395	COG0300	oxidoreductase activity
FOC85_22400	COG4122	O-methyltransferase activity
FOC85_22430	COG0460	homoserine dehydrogenase
FOC85_22455	COG1316	TRANSCRIPTIONal
FOC85_22465	COG0745	RESPONSE REGULATOR receiver
FOC85_22470	COG5002	protein histidine kinase activity
FOC85_22485	COG1285	pathogenesis
FOC85_22490	COG1247	-acetyltransferase
FOC85_22500	COG4264	IucA IucC family
FOC85_22505	COG0318	PFAM AMP-dependent synthetase and ligase
FOC85_22520	COG1082	Xylose isomerase domain protein TIM barrel
FOC85_22530	COG2814	Major facilitator Superfamily
FOC85_22535	COG1279	arginine transmembrane transporter activity
FOC85_22540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_22550	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC85_22585	COG0577	efflux transmembrane transporter activity
FOC85_22590	COG2002	toxin-antitoxin pair type II binding
FOC85_22595	COG1404	Belongs to the peptidase S8 family
FOC85_22600	COG0640	Transcriptional regulator
FOC85_22605	COG0667	Aldo Keto reductase
FOC85_22610	COG2814	Major facilitator Superfamily
FOC85_22635	COG0840	transmembrane signaling receptor activity
FOC85_22650	COG3949	Membrane
FOC85_22655	COG0783	Belongs to the Dps family
FOC85_22670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC85_22680	COG1231	oxidoreductase activity
FOC85_22690	COG4989	oxidoreductase activity
FOC85_22695	COG0523	cobalamin synthesis protein
FOC85_22700	COG0456	acetyltransferase
FOC85_22720	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC85_22720	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC85_22730	COG0702	epimerase
FOC85_22740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC85_22750	COG4166	transmembrane transport
FOC85_22765	COG0406	alpha-ribazole phosphatase activity
FOC85_22775	COG5337	Spore coat protein CotH
FOC85_22780	COG1051	belongs to the nudix hydrolase family
FOC85_22785	COG0586	Pfam SNARE associated Golgi protein
FOC85_22790	COG2244	polysaccharide biosynthetic process
FOC85_22800	COG0701	Predicted permease
FOC85_22805	COG3689	TIGRFAM TIGR03943 family protein
FOC85_22810	COG1607	acyl-coa hydrolase
FOC85_22820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC85_22835	COG0702	epimerase
FOC85_22840	COG2839	Protein conserved in bacteria
FOC85_22845	COG1253	flavin adenine dinucleotide binding
FOC85_22860	COG1114	Component of the transport system for branched-chain amino acids
FOC85_22865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC85_22885	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC85_22895	COG1876	peptidase activity
FOC85_22910	COG2211	Major facilitator Superfamily
FOC85_22925	COG2368	4-hydroxyphenylacetate
FOC85_22935	COG0196	riboflavin kinase activity
FOC85_22950	COG0251	oxidation-reduction process
FOC85_22960	COG3971	2-oxopent-4-enoate hydratase activity
FOC85_22980	COG1942	4-Oxalocrotonate Tautomerase
FOC85_22990	COG0561	phosphatase activity
FOC85_23000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC85_23005	COG4106	trans-aconitate 2-methyltransferase activity
FOC85_23020	COG1819	glycosyl
FOC85_23025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC85_23030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_23060	COG0456	acetyltransferase
FOC85_23140	COG3874	Sporulation protein YtfJ
FOC85_23165	COG2226	methyltransferase
FOC85_23190	COG0346	lactoylglutathione lyase activity
FOC85_23205	COG1595	DNA-templated transcription, initiation
FOC85_23220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC85_23220	COG0426	domain, Protein
FOC85_23230	COG0386	Belongs to the glutathione peroxidase family
FOC85_23235	COG1305	Transglutaminase-like
FOC85_23240	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC85_23245	COG0714	Associated with various cellular activities
FOC85_23260	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC85_23265	COG1140	nitrate reductase beta subunit
FOC85_23270	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC85_23275	COG2181	nitrate reductase activity
FOC85_23280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC85_23285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC85_23290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC85_23300	COG0314	molybdopterin synthase activity
FOC85_23310	COG2223	nitrite transmembrane transporter activity
FOC85_23320	COG1648	precorrin-2 dehydrogenase activity
FOC85_23330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC85_23330	COG1587	Uroporphyrinogen-III synthase
FOC85_23335	COG2146	nitrite reductase [NAD(P)H] activity
FOC85_23340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC85_23345	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC85_23370	COG2359	stage V sporulation protein S
FOC85_23430	COG1418	mRNA catabolic process
FOC85_23435	COG0488	(ABC) transporter
FOC85_23450	COG0629	single-stranded DNA binding
FOC85_23465	COG1413	lyase activity
FOC85_23480	COG2136	Putative SAM-dependent methyltransferase
FOC85_23480	COG2521	methyltransferase
FOC85_23525	COG0017	Asparaginyl-tRNA synthetase
FOC85_23545	COG1674	ftsk spoiiie
FOC85_23665	COG1929	Belongs to the glycerate kinase type-1 family
FOC85_23670	COG0471	metal ion transport
FOC85_23675	COG0745	RESPONSE REGULATOR receiver
FOC85_23680	COG5002	protein histidine kinase activity
FOC85_23680	COG3850	Histidine kinase
FOC85_23695	COG0733	neurotransmitter:sodium symporter activity
FOC85_23720	COG2610	gluconate transmembrane transporter activity
FOC85_23725	COG1454	alcohol dehydrogenase
FOC85_23730	COG1794	racemase activity, acting on amino acids and derivatives
FOC85_23740	COG0456	acetyltransferase
FOC85_23745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC85_23755	COG1131	(ABC) transporter
FOC85_23760	COG4473	ABC transporter
FOC85_23770	COG0546	phosphoglycolate phosphatase activity
FOC85_23790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC85_23795	COG3250	beta-galactosidase activity
FOC85_23810	COG0768	penicillin binding
FOC85_23820	COG0204	Acyl-transferase
FOC85_23825	COG1272	protein, Hemolysin III
FOC85_23835	COG0805	protein transport
FOC85_23845	COG1307	EDD domain protein, DegV family
FOC85_23850	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC85_23855	COG1999	signal sequence binding
FOC85_23860	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC85_23865	COG0367	asparagine synthase
FOC85_23885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC85_23890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC85_23910	COG1335	isochorismatase
FOC85_23915	COG1051	belongs to the nudix hydrolase family
FOC85_23925	COG0668	transmembrane transport
FOC85_23930	COG2203	Gaf domain
FOC85_23930	COG4585	Histidine kinase
FOC85_23935	COG2197	response regulator
FOC85_23945	COG1064	alcohol dehydrogenase
FOC85_24000	COG1125	glycine betaine transport
FOC85_24000	COG0517	IMP dehydrogenase activity
FOC85_24005	COG1174	glycine betaine transport
FOC85_24040	COG1253	flavin adenine dinucleotide binding
FOC85_24045	COG1012	belongs to the aldehyde dehydrogenase family
FOC85_24050	COG5506	Protein of unknown function (DUF1694)
FOC85_24065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC85_24070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC85_24075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC85_24080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC85_24085	COG0456	acetyltransferase
FOC85_24090	COG3829	transcription factor binding
FOC85_24095	COG1509	lysine 2,3-aminomutase activity
FOC85_24130	COG0515	serine threonine protein kinase
FOC85_24130	COG3064	Membrane
FOC85_24130	COG4991	sh3 domain protein
FOC85_24135	COG4326	sporulation control protein
FOC85_24140	COG0671	phosphoesterase, PA-phosphatase related
FOC85_24145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC85_24150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC85_24210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC85_24245	COG0300	oxidoreductase activity
FOC85_24265	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC85_24265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC85_24275	COG4841	protein insertion into membrane
FOC85_24280	COG0372	Belongs to the citrate synthase family
FOC85_24285	COG2079	MmgE PrpD family protein
FOC85_24290	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC85_24295	COG1960	acyl-CoA dehydrogenase activity
FOC85_24300	COG2084	Dehydrogenase
FOC85_24310	COG1280	lysine exporter protein (LysE YggA)
FOC85_24315	COG1024	Enoyl-CoA hydratase
FOC85_24330	COG0420	3'-5' exonuclease activity
FOC85_24335	COG0419	ATPase involved in DNA repair
FOC85_24355	COG2223	nitrite transmembrane transporter activity
FOC85_24360	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_24365	COG1169	isochorismate synthase
FOC85_24370	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC85_24375	COG3433	isochorismatase activity
FOC85_24375	COG1535	isochorismatase
FOC85_24380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC85_24385	COG3251	PFAM MbtH domain protein
FOC85_24390	COG2814	Major facilitator Superfamily
FOC85_24405	COG0776	regulation of translation
FOC85_24415	COG2318	DinB family
FOC85_24425	COG1115	amino acid carrier protein
FOC85_24440	COG2329	Antibiotic biosynthesis monooxygenase
FOC85_24445	COG1187	pseudouridine synthase activity
FOC85_24450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC85_24460	COG1136	(ABC) transporter
FOC85_24470	COG0596	Alpha beta hydrolase
FOC85_24475	COG2814	Major facilitator Superfamily
FOC85_24495	COG2226	methyltransferase
FOC85_24540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_24575	COG1247	-acetyltransferase
FOC85_24615	COG2226	methyltransferase
FOC85_24620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_24630	COG1278	Cold shock
FOC85_24645	COG0010	Belongs to the arginase family
FOC85_24655	COG0583	DNA-binding transcription factor activity
FOC85_24660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC85_24675	COG0583	DNA-binding transcription factor activity
FOC85_24680	COG2258	MOSC domain
FOC85_24695	COG1132	(ABC) transporter
FOC85_24700	COG1132	(ABC) transporter
FOC85_24720	COG1396	sequence-specific DNA binding
FOC85_24750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC85_24760	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC85_24765	COG1595	DNA-templated transcription, initiation
FOC85_24790	COG1649	PFAM Uncharacterised BCR, COG1649
FOC85_24815	COG2971	BadF BadG BcrA BcrD
FOC85_24825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC85_24860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC85_24950	COG0582	viral genome integration into host DNA
FOC85_24970	COG0577	efflux transmembrane transporter activity
FOC85_24970	COG1136	(ABC) transporter
FOC85_24975	COG3615	Tellurite resistance protein tehB
FOC85_24975	COG0500	methyltransferase
FOC85_25070	COG1846	Transcriptional regulator
FOC85_25105	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC85_25115	COG0110	maltose O-acetyltransferase activity
FOC85_25130	COG0768	penicillin binding
FOC85_25135	COG1595	DNA-templated transcription, initiation
FOC85_25145	COG0768	penicillin binding
FOC85_25155	COG2367	Beta-lactamase
FOC85_25165	COG1609	Transcriptional regulator
FOC85_25170	COG2814	Major facilitator Superfamily
FOC85_25175	COG0673	inositol 2-dehydrogenase activity
FOC85_25205	COG3718	enzyme involved in inositol metabolism
FOC85_25230	COG0737	Belongs to the 5'-nucleotidase family
FOC85_25240	COG0457	Tetratricopeptide repeat
FOC85_25245	COG1476	TRANSCRIPTIONal
FOC85_25260	COG1876	peptidase activity
FOC85_25280	COG1309	transcriptional regulator
FOC85_25295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_25315	COG1252	NADH dehydrogenase
FOC85_25320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC85_25350	COG1960	acyl-CoA dehydrogenase activity
FOC85_25355	COG0439	Biotin carboxylase
FOC85_25360	COG0511	ligase activity, forming carbon-carbon bonds
FOC85_25365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC85_25370	COG1024	Enoyl-CoA hydratase
FOC85_25375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC85_25380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC85_25390	COG1247	-acetyltransferase
FOC85_25395	COG0572	uridine kinase
FOC85_25405	COG2318	DinB family
FOC85_25410	COG1686	Belongs to the peptidase S11 family
FOC85_25435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC85_25455	COG3227	Zinc metalloprotease (Elastase)
FOC85_25475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC85_25475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC85_25540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_25580	COG3386	PFAM SMP-30 Gluconolaconase
FOC85_25590	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FOC85_25595	COG3773	Cell wall hydrolase
FOC85_25605	COG0745	RESPONSE REGULATOR receiver
FOC85_25610	COG2205	protein histidine kinase activity
FOC85_25635	COG1136	(ABC) transporter
FOC85_25640	COG0577	efflux transmembrane transporter activity
FOC85_25660	COG0460	homoserine dehydrogenase
FOC85_25665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_25675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC85_25750	COG2124	cytochrome p450
FOC85_25785	COG0561	phosphatase activity
FOC85_25790	COG5002	protein histidine kinase activity
FOC85_25800	COG1819	glycosyl
FOC85_25805	COG1794	racemase activity, acting on amino acids and derivatives
FOC85_25830	COG2205	protein histidine kinase activity
FOC85_25840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC85_25845	COG0604	alcohol dehydrogenase
FOC85_25850	COG0671	phosphoesterase, PA-phosphatase related
FOC85_25865	COG4221	oxidoreductase activity
FOC85_25875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC85_25915	COG0693	protein deglycase activity
FOC85_25920	COG0456	acetyltransferase
FOC85_25930	COG2814	Major facilitator Superfamily
FOC85_25945	COG0584	glycerophosphoryl diester phosphodiesterase
FOC85_25965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_25970	COG0697	spore germination
FOC85_26005	COG2223	nitrite transmembrane transporter activity
FOC85_26010	COG2816	NAD+ diphosphatase activity
FOC85_26015	COG0592	DNA-directed DNA polymerase activity
FOC85_26020	COG1051	belongs to the nudix hydrolase family
FOC85_26040	COG0406	alpha-ribazole phosphatase activity
FOC85_26050	COG3878	Protein conserved in bacteria
FOC85_26070	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC85_26110	COG0322	excinuclease ABC activity
FOC85_26145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC85_26170	COG1011	Hydrolase
FOC85_26190	COG1523	belongs to the glycosyl hydrolase 13 family
FOC85_26195	COG3227	Zinc metalloprotease (Elastase)
FOC85_26215	COG0346	lactoylglutathione lyase activity
FOC85_26220	COG0201	protein transport
FOC85_26230	COG0697	spore germination
FOC85_26235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC85_26270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_26285	COG2959	enzyme of heme biosynthesis
FOC85_26320	COG1309	transcriptional regulator
FOC85_26355	COG3284	Transcriptional regulator
FOC85_26370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC85_26375	COG1349	DNA-binding transcription factor activity
FOC85_26395	COG1959	2 iron, 2 sulfur cluster binding
FOC85_26410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC85_26415	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC85_26420	COG0022	dehydrogenase e1 component
FOC85_26425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC85_26435	COG1028	Short-chain dehydrogenase reductase Sdr
FOC85_26440	COG0456	acetyltransferase
FOC85_26440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC85_26445	COG0572	uridine kinase
FOC85_26455	COG0494	nUDIX hydrolase
FOC85_26480	COG4176	ABC-type proline glycine betaine transport system permease component
FOC85_26485	COG4175	Glycine betaine
FOC85_26485	COG0517	IMP dehydrogenase activity
FOC85_26510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC85_26515	COG2153	protein acetylation
FOC85_26520	COG3397	chitin binding
FOC85_26530	COG2205	protein histidine kinase activity
FOC85_26535	COG2226	methyltransferase
FOC85_26540	COG2315	Protein conserved in bacteria
FOC85_26545	COG2153	protein acetylation
FOC85_26550	COG2333	competence protein COMEC
FOC85_26550	COG0658	competence protein
FOC85_26600	COG3973	AAA domain
FOC85_26620	COG0514	ATP-dependent DNA helicase (RecQ)
FOC85_26645	COG4637	Psort location Cytoplasmic, score
FOC85_26670	COG3397	chitin binding
FOC85_26685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC85_26690	COG1115	amino acid carrier protein
FOC85_26695	COG1012	belongs to the aldehyde dehydrogenase family
FOC85_26700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC85_26710	COG3938	Belongs to the proline racemase family
FOC85_26715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC85_26755	COG0586	Pfam SNARE associated Golgi protein
FOC85_26770	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC85_26775	COG0519	Catalyzes the synthesis of GMP from XMP
FOC85_26780	COG4166	transmembrane transport
FOC85_26790	COG4948	Mandelate Racemase Muconate Lactonizing
FOC85_26835	COG2936	dipeptidyl-peptidase activity
FOC85_26840	COG5002	protein histidine kinase activity
FOC85_26845	COG0745	RESPONSE REGULATOR receiver
FOC85_26875	COG1164	Oligoendopeptidase f
FOC85_26880	COG0531	amino acid
FOC85_26885	COG1522	sequence-specific DNA binding
FOC85_26890	COG1307	EDD domain protein, DegV family
FOC85_26925	COG2814	Major facilitator Superfamily
FOC85_26935	COG1664	Polymer-forming cytoskeletal
FOC85_26940	COG0789	Transcriptional regulator
FOC85_26950	COG2814	Major facilitator Superfamily
FOC85_26950	COG0477	Major facilitator Superfamily
FOC85_26970	COG2261	transglycosylase associated protein
FOC85_26985	COG2226	methyltransferase
FOC85_27015	COG0436	Aminotransferase
FOC85_27020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC85_27025	COG5146	pantothenate kinase activity
FOC85_27030	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC85_27045	COG1131	(ABC) transporter
FOC85_27090	COG0628	permease
FOC85_27100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC85_27105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC85_27110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC85_27145	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC85_27170	COG0697	spore germination
FOC85_27175	COG2318	DinB family
FOC85_27215	COG0861	Integral membrane protein TerC family
FOC85_27220	COG1368	sulfuric ester hydrolase activity
FOC85_27225	COG0488	(ABC) transporter
FOC85_27235	COG1033	growth of symbiont in host cell
FOC85_27235	COG2409	Drug exporters of the RND superfamily
FOC85_27240	COG1309	transcriptional regulator
FOC85_27255	COG0287	Prephenate dehydrogenase
FOC85_27260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC85_27270	COG1605	Chorismate mutase
FOC85_27270	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC85_27310	COG1388	LysM domain
FOC85_27310	COG3584	3D domain protein
FOC85_27320	COG2610	gluconate transmembrane transporter activity
FOC85_27325	COG1024	Enoyl-CoA hydratase
FOC85_27335	COG3829	transcription factor binding
FOC85_27335	COG3290	protein histidine kinase activity
FOC85_27355	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC85_27360	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC85_27370	COG2390	Transcriptional regulator
FOC85_27375	COG1070	Carbohydrate kinase
FOC85_27410	COG2329	Antibiotic biosynthesis monooxygenase
FOC85_27430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC85_27445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC85_27450	COG4187	Peptidase family M20/M25/M40
FOC85_27455	COG1414	Transcriptional regulator
FOC85_27465	COG1690	Belongs to the RtcB family
FOC85_27470	COG3239	Fatty acid desaturase