locus-tag class description FOC86_00165 ENOG4105K4H Nlp p60 protein FOC86_00240 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC86_00270 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC86_00295 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC86_00320 ENOG4105DVF Cytosine-specific methyltransferase FOC86_00325 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_00360 ENOG4107QJE Chromosome Partitioning Protein FOC86_00390 ENOG4105EWC Purine nucleoside phosphorylase FOC86_00435 ENOG4105EMD TRANSCRIPTIONal FOC86_00440 ENOG4105VCP PTS System FOC86_00445 ENOG4105VZJ PTS System FOC86_00465 ENOG41069ER domain protein FOC86_00470 ENOG4107RBB ABC transporter, permease FOC86_00475 ENOG4105C19 ABC transporter FOC86_00505 ENOG4105WEF catalase FOC86_00540 ENOG4107T5V SNARE associated Golgi FOC86_00575 ENOG4105CUB amino acid FOC86_00580 ENOG4107RWR Sodium hydrogen exchanger FOC86_00590 ENOG4106KNT transcriptional regulator FOC86_00630 ENOG4108YXU transcriptional regulator AsnC family FOC86_00645 ENOG4105KPY Small multidrug resistance protein FOC86_00670 ENOG4105NF4 modulator of drug activity FOC86_00675 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC86_00680 ENOG4105E5W Transporter FOC86_00690 ENOG4107RKG DJ-1/PfpI family FOC86_00695 ENOG4105CH6 catalase FOC86_00705 ENOG4105D5Q Arginine ornithine antiporter FOC86_00710 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FOC86_00720 ENOG4105C26 Dehydrogenase FOC86_00725 ENOG4105BZ1 (ABC) transporter FOC86_00730 ENOG4105BZ1 (ABC) transporter FOC86_00740 ENOG4105DRP amino acid AbC transporter FOC86_00745 ENOG4105CDA abc transporter atp-binding protein FOC86_00760 ENOG410839P FOC86_00795 ENOG4107FQX Alpha-acetolactate decarboxylase FOC86_00815 ENOG4105D4P Coproporphyrinogen iii oxidase FOC86_00830 ENOG4105CHH sulfate transporter FOC86_00870 ENOG4105IEH endo-beta-N-acetylglucosaminidase FOC86_00885 ENOG4105CGU Enoyl-CoA hydratase FOC86_00905 ENOG4105DER m42 family FOC86_00950 ENOG4108IBT Inherit from COG: transposase FOC86_01030 ENOG4105F32 YngK protein FOC86_01070 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_01080 ENOG4108JQ7 (ABC) transporter FOC86_01110 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FOC86_01135 ENOG4105CSH Transporter FOC86_01145 ENOG4108MRH transcriptional regulatory protein FOC86_01200 ENOG4105CDU Replicative dna helicase FOC86_01340 ENOG4105CID antiterminator FOC86_01345 ENOG4105C5Y PTS System FOC86_01350 ENOG4105CS2 ec 3.2.1.21 FOC86_01360 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC86_01390 ENOG4105CMT Dihydroxyacetone kinase FOC86_01400 ENOG4105CMT Dihydroxyacetone kinase FOC86_01435 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FOC86_01505 ENOG4105WN5 stage II sporulation protein FOC86_01515 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_01525 ENOG4108MJI response regulator FOC86_01530 ENOG4105BZU Histidine kinase FOC86_01535 ENOG4105BZU Histidine kinase FOC86_01570 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_01615 ENOG4107VRP DNA repair exonuclease FOC86_01620 ENOG4106D4I domain protein FOC86_01655 ENOG4108MUZ hydrolase FOC86_01685 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC86_01700 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOC86_01720 ENOG4105EMN RNA polymerase sigma factor FOC86_01730 ENOG4105CNI cell division protein FtsW FOC86_01745 ENOG4105C57 major facilitator superfamily FOC86_01750 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_01760 ENOG4105EEM helicase FOC86_01765 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_01790 ENOG4105K59 histidine triad (HIT) protein FOC86_01825 ENOG410905X membrane-flanked domain protein FOC86_01830 ENOG4105CKV Membrane FOC86_01860 ENOG410905X membrane-flanked domain protein FOC86_01865 ENOG4105CKV Membrane FOC86_01870 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FOC86_01875 ENOG4105BZ4 penicillin-binding protein FOC86_01890 ENOG4105C1Q protoporphyrinogen oxidase FOC86_01920 ENOG4105ECB domain protein FOC86_01940 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) FOC86_01950 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC86_01960 ENOG4106AXD FOC86_01965 ENOG4108RQ5 Beta-lactamase domain-containing protein FOC86_01970 ENOG4105DF9 Lipoate-protein, ligase FOC86_01980 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_02000 ENOG4107RN3 metallophosphoesterase FOC86_02005 ENOG4107TVP HD domain protein FOC86_02015 ENOG4108AEY RNA polymerase sigma factor FOC86_02020 ENOG41086D8 Transcriptional regulator FOC86_02040 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_02065 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FOC86_02090 ENOG4107QP3 malate synthase g FOC86_02120 ENOG4105XVF Competence transcription factor FOC86_02125 ENOG4105BZU Histidine kinase FOC86_02200 ENOG4105ERH Fumarylacetoacetate hydrolase FOC86_02225 ENOG4105CAQ asparagine synthetase FOC86_02235 ENOG4105CH6 catalase FOC86_02240 ENOG4105BZU Histidine kinase FOC86_02265 ENOG4105QNR S1 RNA binding domain protein FOC86_02270 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_02280 ENOG4107AYK membrAne FOC86_02285 ENOG41073B9 FOC86_02295 ENOG4108KP7 hydrolase FOC86_02305 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOC86_02330 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC86_02335 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOC86_02350 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC86_02365 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC86_02370 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_02380 ENOG4108JQ7 (ABC) transporter FOC86_02385 ENOG4105UQX Mate efflux family protein FOC86_02405 ENOG4108ZCF integral membrane protein FOC86_02415 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC86_02425 ENOG4105DPN Oligoendopeptidase f FOC86_02440 ENOG4108Z18 K06886 hemoglobin FOC86_02445 ENOG4105MIX Adenylate cyclase FOC86_02465 ENOG4105EMS pseudouridine synthase FOC86_02485 ENOG4105K64 Glycosyl transferase, family 2 FOC86_02505 ENOG4107TVC Glycosyl transferase, family 2 FOC86_02525 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC86_02530 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC86_02540 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FOC86_02615 ENOG4105CK7 Sodium proline symporter FOC86_02625 ENOG4105DDQ anthranilate synthase FOC86_02705 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC86_02725 ENOG4105C7S Dehydrogenase FOC86_02735 ENOG4105VZ8 Transcriptional regulator FOC86_02780 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) FOC86_02790 ENOG4105DZ1 carboxypeptidase FOC86_02795 ENOG4105VFR signal peptidase FOC86_02830 ENOG4105C26 Dehydrogenase FOC86_02840 ENOG4105F38 ABC transporter, permease FOC86_02845 ENOG4105D38 putrescine abc transporter FOC86_02850 ENOG4107RUE extracellular solute-binding protein family 1 FOC86_02860 ENOG4105EYF MMPL domain protein FOC86_02870 ENOG4108YBP pseudouridine synthase FOC86_02880 ENOG4105K4I Scp-like extracellular FOC86_02885 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOC86_02890 ENOG4105CQB FAD linked oxidase domain protein FOC86_02905 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_02910 ENOG4105BZU Histidine kinase FOC86_02915 ENOG4105JXH GntR family transcriptional regulator FOC86_02935 ENOG4106A3R peptidase FOC86_02945 ENOG4108QTI )-transporter FOC86_02950 ENOG4107TS3 membrane protein, TerC FOC86_02955 ENOG4105CZN Potassium uptake protein FOC86_02960 ENOG410681C small acid-soluble spore protein FOC86_02965 ENOG4108Z7G MaoC domain protein dehydratase FOC86_02985 ENOG4105CHR reductase FOC86_02995 ENOG4105MWK D-amino acid dehydrogenase, small subunit FOC86_03015 ENOG4105C4Y ABC transporter FOC86_03020 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC86_03025 ENOG4107RCV ABC transporter, permease FOC86_03045 ENOG4105E98 transcriptional regulator DeoR family FOC86_03055 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FOC86_03065 ENOG4105PXI polysaccharide deacetylase FOC86_03075 ENOG4105BZU Histidine kinase FOC86_03080 ENOG41090MY MarR family Transcriptional regulator FOC86_03090 ENOG4106DF1 FOC86_03095 ENOG4105BZU Histidine kinase FOC86_03105 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOC86_03110 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOC86_03150 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC86_03170 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC86_03175 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC86_03180 ENOG4105CZV ABC transporter FOC86_03190 ENOG4105CJ1 ABC, transporter FOC86_03230 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC86_03235 ENOG4105EA8 2-Nitropropane dioxygenase FOC86_03240 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC86_03250 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC86_03275 ENOG4105NQC Flavodoxin FOC86_03345 ENOG4105CZN Potassium uptake protein FOC86_03350 ENOG41063Y9 FOC86_03355 ENOG4105KBJ sporulation protein ytfj FOC86_03375 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC86_03380 ENOG4105C7K acetolactate synthase FOC86_03385 ENOG4108ZP8 Acetolactate synthase small subunit FOC86_03460 ENOG4107RVV histidinol phosphate phosphatase, hisj family FOC86_03475 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC86_03480 ENOG4105E0M Sulfatase FOC86_03490 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOC86_03510 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FOC86_03515 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FOC86_03525 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC86_03530 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC86_03535 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC86_03540 ENOG4105C8J )-transporter FOC86_03570 ENOG4105DFD Na H antiporter FOC86_03590 ENOG4105ENE Histidine kinase FOC86_03595 ENOG4105WH1 Two component transcriptional regulator luxr family FOC86_03615 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FOC86_03660 ENOG4105CJ3 phosphate transporter FOC86_03665 ENOG4107GRR phosphate transport regulator FOC86_03670 ENOG4105BZ4 penicillin-binding protein FOC86_03685 ENOG4105BZU Histidine kinase FOC86_03690 ENOG4105I3N Conserved Protein FOC86_03705 ENOG4105BZU Histidine kinase FOC86_03740 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC86_03745 ENOG4105DZ1 carboxypeptidase FOC86_03750 ENOG4108JIC nucleoside recognition domain protein FOC86_03760 ENOG4105FE9 pseudouridine synthase FOC86_03770 ENOG4107TWT Cytochrome c biogenesis protein FOC86_03775 ENOG4105CRE cytochrome C FOC86_03780 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_03785 ENOG4105BZU Histidine kinase FOC86_03790 ENOG4108WBT adenosyltransferase FOC86_03795 ENOG41063SB peptidase FOC86_03805 ENOG4108SAX Membrane FOC86_03820 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC86_03825 ENOG4105I7S Abortive infection protein FOC86_03835 ENOG4107RGJ metallophosphoesterase FOC86_03840 ENOG4107X2D transcriptional regulator, merr family FOC86_03845 ENOG4108S6Z Negative regulator of genetic competence FOC86_03870 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FOC86_03875 ENOG4105HDK L-asparaginase FOC86_03910 ENOG4105S2F FOC86_03915 ENOG41065D1 FOC86_03945 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FOC86_03960 ENOG4105XXQ heptaprenyl diphosphate synthase component I FOC86_03970 ENOG4105EAH synthase FOC86_03995 ENOG41068YB TPR repeat-containing protein FOC86_04010 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FOC86_04015 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FOC86_04020 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit FOC86_04050 ENOG4108JYZ YitT family FOC86_04055 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FOC86_04070 ENOG4105FJR Lmbe family FOC86_04075 ENOG4105CPK Glycosyl transferase (Group 1 FOC86_04110 ENOG4105DVT helicase FOC86_04115 ENOG4105YAC FOC86_04135 ENOG4105CSM endonuclease III FOC86_04145 ENOG4105BZ4 penicillin-binding protein FOC86_04205 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FOC86_04215 ENOG4105DVT helicase FOC86_04220 ENOG4105CTD carboxy-peptidase FOC86_04235 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC86_04245 ENOG4105C2W permease FOC86_04250 ENOG4105DHF Membrane FOC86_04255 ENOG410890F Dynamin family FOC86_04265 ENOG4108W0I acetyltransferase FOC86_04275 ENOG4105KHC sulfurtransferase FOC86_04305 ENOG4106032 Glutathionylspermidine synthase FOC86_04365 ENOG4105CPK Glycosyl transferase (Group 1 FOC86_04380 ENOG4108SZE gCN5-related N-acetyltransferase FOC86_04400 ENOG41081VK Ribonuclease FOC86_04465 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC86_04475 ENOG4107RWR Sodium hydrogen exchanger FOC86_04480 ENOG4105CN5 Metallo-Beta-Lactamase FOC86_04485 ENOG4108Z5V transcriptional regulator, merr family FOC86_04495 ENOG4105H67 Protein of unknown function (DUF421) FOC86_04500 ENOG41080C8 DUF218 domain FOC86_04565 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC86_04580 ENOG4107R0U MotA TolQ exbB proton channel FOC86_04585 ENOG4105ER2 Ompa motb domain protein FOC86_04590 ENOG4107YTP response regulator receiver protein FOC86_04595 ENOG4105CBS Chea signal transduction histidine kinase FOC86_04600 ENOG4105DD5 Flagellar motor switch protein FOC86_04615 ENOG4105BZU Histidine kinase FOC86_04635 ENOG4105E1Q flagellar hook-associated protein FOC86_04640 ENOG4105DTJ flagellar hook-associated protein FOC86_04645 ENOG4107TPX flagellar hook-associated FOC86_04660 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOC86_04665 ENOG4108ZC9 flagellar basal-body rod protein flgc FOC86_04675 ENOG4107U2N Flagellar M-ring protein FOC86_04680 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC86_04710 ENOG4105BZE flagellar hook protein, FlgE FOC86_04725 ENOG4107R88 Chemotaxis protein (CheV) FOC86_04735 ENOG4105I03 Flagellin FOC86_04740 ENOG4105I03 Flagellin FOC86_04745 ENOG4105E4C Lytic transglycosylase catalytic FOC86_04755 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC86_04760 ENOG4105DD5 Flagellar motor switch protein FOC86_04770 ENOG4105CN7 Flagellar biosynthetic protein FliP FOC86_04775 ENOG4105VS8 Flagellar biosynthetic protein fliq FOC86_04785 ENOG4105D00 flagellar biosynthetic protein flhB FOC86_04790 ENOG4105D7B Flagellar biosynthesis protein flha FOC86_04795 ENOG4105FZW flagellar biosynthesis regulator FlhF FOC86_04800 ENOG4105KTQ flagellar basal-body rod protein FOC86_04805 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC86_04840 ENOG4105KAC Antibiotic biosynthesis monooxygenase FOC86_04870 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC86_04875 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC86_04880 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FOC86_04885 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FOC86_04925 ENOG4105CVJ phosphoglycerate mutase FOC86_04945 ENOG4105K56 Transcriptional regulator FOC86_04955 ENOG4105CAQ asparagine synthetase FOC86_04985 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC86_05000 ENOG4105DQ6 Transposase FOC86_05045 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC86_05065 ENOG4105PGM cation diffusion facilitator family transporter FOC86_05075 ENOG4105DRR Transcriptional regulator, GntR family FOC86_05080 ENOG4108UZ3 Transporter FOC86_05085 ENOG4105CKI cobalamin synthesis protein FOC86_05090 ENOG4108PJD permease FOC86_05105 ENOG4105DFD Na H antiporter FOC86_05110 ENOG4105VUF Transcriptional regulator FOC86_05120 ENOG4105C9Q fumarate hydratase class II FOC86_05135 ENOG4105C5X domain protein FOC86_05145 ENOG4107QJQ Mate efflux family protein FOC86_05150 ENOG4105EC3 peptidase S51, dipeptidase E FOC86_05170 ENOG4107QIV Cytochrome c biogenesis protein FOC86_05200 ENOG4106BRA Membrane FOC86_05235 ENOG4105CJ1 ABC, transporter FOC86_05265 ENOG4108IBT Inherit from COG: transposase FOC86_05275 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC86_05285 ENOG4108IJ0 Aspartate ammonia-lyase FOC86_05290 ENOG4105C6K Malic enzyme FOC86_05350 ENOG4105FVX FOC86_05380 ENOG4105CSR polyphosphate kinase 2 FOC86_05385 ENOG4105U3E Transcriptional regulator FOC86_05395 ENOG4105DXI Major Facilitator superfamily FOC86_05410 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC86_05420 ENOG4105EU0 Major facilitator Superfamily FOC86_05425 ENOG4105C6T cysteine synthase FOC86_05445 ENOG4105C8J )-transporter FOC86_05455 ENOG4105X5K response regulator receiver protein FOC86_05460 ENOG4105H67 Protein of unknown function (DUF421) FOC86_05475 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FOC86_05480 ENOG4105CHR reductase FOC86_05485 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC86_05490 ENOG4105C7K acetolactate synthase FOC86_05495 ENOG4108ZP8 Acetolactate synthase small subunit FOC86_05510 ENOG4105C7B Threonine dehydratase FOC86_05535 ENOG4105C6X Major Facilitator FOC86_05540 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOC86_05550 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC86_05555 ENOG4105DY9 regulatoR FOC86_05560 ENOG4105CYC Transferase FOC86_05580 ENOG4105F6J Alpha beta hydrolase fold FOC86_05615 ENOG41068WN FOC86_05635 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FOC86_05685 ENOG4107RHR regulatoR FOC86_05695 ENOG4105D9N nucleoside FOC86_05700 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FOC86_05730 ENOG4107RAQ aminopeptidase FOC86_05735 ENOG4107R16 Multicopper oxidase FOC86_05790 ENOG4108T5E Copper resistance protein FOC86_05795 ENOG4105KTB nuclear export factor GLE1 FOC86_05805 ENOG4107RT3 EamA-like transporter family FOC86_05810 ENOG4105GZI Transcriptional regulator FOC86_05815 ENOG4108Z40 Transcriptional regulator FOC86_05820 ENOG4107ZXU DSBA oxidoreductase FOC86_05825 ENOG4108TVJ Nitroreductase FOC86_05830 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC86_05835 ENOG4106F5Q Membrane FOC86_05850 ENOG4105CKI cobalamin synthesis protein FOC86_05860 ENOG4105C0Z ABC transporter FOC86_05865 ENOG4108IV0 ABC, transporter FOC86_05870 ENOG4105C32 Amino acid ABC transporter (Permease) FOC86_05880 ENOG4105SKE transcriptional Regulator LysR family FOC86_05910 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC86_05915 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC86_05920 ENOG4108JJ9 ABC, transporter FOC86_05925 ENOG4108JJ8 (ABC) transporter FOC86_05940 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC86_05970 ENOG4105BZ1 (ABC) transporter FOC86_05975 ENOG4105EFI regulatoR FOC86_05980 ENOG4105BZU Histidine kinase FOC86_06000 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FOC86_06010 ENOG4106AKJ FOC86_06025 ENOG4105D6E homoserine dehydrogenase FOC86_06050 ENOG4108KGH TRANSCRIPTIONal FOC86_06060 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_06065 ENOG4105BZU Histidine kinase FOC86_06080 ENOG4105KT7 mgtC SapB transporter FOC86_06085 ENOG4105VRR gCN5-related N-acetyltransferase FOC86_06095 ENOG4105DUU IucA IucC family protein FOC86_06100 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_06115 ENOG4108WBH protein TIM barrel FOC86_06120 ENOG4105YWU small acid-soluble spore protein FOC86_06130 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOC86_06180 ENOG4105KRN Transcriptional regulator, abrb family FOC86_06190 ENOG4105YVS arsR family transcriptional regulator FOC86_06195 ENOG4107SET aldo keto reductase FOC86_06200 ENOG4107XZQ multidrug resistance protein FOC86_06225 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_06240 ENOG4108K88 Membrane FOC86_06245 ENOG4108WPJ Ferritin-like domain FOC86_06260 ENOG4105DEN Luciferase family FOC86_06275 ENOG4105VMI -acetyltransferase FOC86_06280 ENOG4107QM2 Aldo Keto reductase FOC86_06285 ENOG4105CKI cobalamin synthesis protein FOC86_06295 ENOG4105DSE periplasmic solute binding protein FOC86_06305 ENOG4105K4T epimerase FOC86_06315 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC86_06340 ENOG4107TB6 phosphoglycerate mutase FOC86_06360 ENOG4107T5V SNARE associated Golgi FOC86_06375 ENOG4108PJD permease FOC86_06385 ENOG4108S4H thioesterase Superfamily protein FOC86_06395 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC86_06415 ENOG4105SXS Protein of unknown function (DUF456) FOC86_06420 ENOG4105C37 (CBS) domain FOC86_06440 ENOG4108Z7R Chaperone CsaA FOC86_06460 ENOG4108ZRV stage ii sporulation protein p FOC86_06470 ENOG4108VXD carboxy-peptidase FOC86_06475 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_06480 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC86_06505 ENOG4108X4Q Hydrolase FOC86_06515 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC86_06535 ENOG41087PP glycosyltransferase MGT family FOC86_06540 ENOG4108JYZ YitT family FOC86_06545 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC86_06575 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC86_06615 ENOG4108MGT Required for secretion of EsxA and EsxB FOC86_06695 ENOG4105KBJ sporulation protein ytfj FOC86_06720 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC86_06745 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC86_06755 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOC86_06760 ENOG4105EMN RNA polymerase sigma factor FOC86_06775 ENOG4105CNW domain protein FOC86_06785 ENOG4108V06 Glutathione peroxidase FOC86_06800 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_06810 ENOG4108IUE nitrate reductase beta subunit FOC86_06815 ENOG4105R3A Nitrate reductase FOC86_06825 ENOG4107V6Q Cyclic nucleotide-binding domain FOC86_06830 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC86_06835 ENOG4105D06 uba thif-type nad fad binding protein FOC86_06840 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC86_06845 ENOG4108ZAF Molybdopterin FOC86_06865 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC86_06870 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC86_06875 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC86_06880 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC86_06885 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC86_06890 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FOC86_06930 ENOG4105MCT stage V sporulation protein S FOC86_06955 ENOG4105C5H ABC transporter FOC86_06970 ENOG4108UUM single-stranded DNA-binding protein FOC86_07000 ENOG4107YX5 Pfam:DUF548 FOC86_07035 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC86_07040 ENOG4105C5S asparaginyl-tRNA synthetase FOC86_07045 ENOG4105C8J )-transporter FOC86_07065 ENOG4107XGZ Hydrolase FOC86_07070 ENOG4105CY2 Citrate transporter FOC86_07075 ENOG4105C0A alcohol dehydrogenase FOC86_07090 ENOG4105KD7 acetyltransferase FOC86_07095 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FOC86_07120 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FOC86_07140 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) FOC86_07160 ENOG4107RVG penicillin-binding protein FOC86_07180 ENOG4105E9Q Acyl-transferase FOC86_07185 ENOG4108UT2 hemolysin iii FOC86_07195 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOC86_07205 ENOG4108RCR degv family FOC86_07210 ENOG4105E8R UPF0173 metal-dependent hydrolase FOC86_07215 ENOG4108KF3 Electron transport protein SCO1 SenC FOC86_07220 ENOG4107Y70 Heat shock protein FOC86_07225 ENOG4105CAQ asparagine synthetase FOC86_07240 ENOG4108MES Periplasmic binding protein FOC86_07245 ENOG4105F0I Aminotransferase FOC86_07275 ENOG4107Y70 Heat shock protein FOC86_07280 ENOG4105D8X mechanosensitive ion channel FOC86_07285 ENOG4105BZU Histidine kinase FOC86_07290 ENOG4105WH1 Two component transcriptional regulator luxr family FOC86_07325 ENOG4105CMG Carbohydrate kinase FOC86_07330 ENOG4105CMG Carbohydrate kinase FOC86_07360 ENOG4108IJ8 ABC transporter FOC86_07365 ENOG4105E90 ABC transporter FOC86_07400 ENOG4105C37 (CBS) domain FOC86_07425 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC86_07440 ENOG4107S4Y M20 DapE family protein YgeY FOC86_07445 ENOG4108TSC N-acetyltransferase FOC86_07450 ENOG4108JUB Transcriptional regulator FOC86_07455 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOC86_07495 ENOG4108N23 SpoOM-related protein FOC86_07500 ENOG410841Q phosphoesterase PA-phosphatase related protein FOC86_07510 ENOG4105SZ6 Thioredoxin FOC86_07525 ENOG4108IBT Inherit from COG: transposase FOC86_07630 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_07670 ENOG4105BZ4 penicillin-binding protein FOC86_07675 ENOG4105CZM Major Facilitator FOC86_07680 ENOG4105W8X HesB YadR YfhF-family protein FOC86_07690 ENOG4105DXD 2-methylcitrate dehydratase FOC86_07695 ENOG4105CR4 methylisocitrate lyase FOC86_07700 ENOG4105C1G acyl-Coa dehydrogenase FOC86_07705 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC86_07715 ENOG4105N14 lysine exporter protein LysE YggA FOC86_07720 ENOG4105E39 Enoyl-CoA hydratase FOC86_07735 ENOG4107RFY SbcCD D subunit FOC86_07740 ENOG4105EYH Exonuclease FOC86_07765 ENOG4105FCD Major Facilitator FOC86_07770 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOC86_07775 ENOG4105E4F Isochorismate synthase FOC86_07780 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOC86_07785 ENOG4105WQI isochorismatase FOC86_07790 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_07795 ENOG4105WQT MbtH domain protein FOC86_07800 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_07815 ENOG4105K70 DNA-binding protein FOC86_07835 ENOG4105BZG amino acid carrier protein FOC86_07855 ENOG4105FE9 pseudouridine synthase FOC86_07860 ENOG4105C22 threonyL-tRNA synthetase FOC86_07865 ENOG4105C19 ABC transporter FOC86_07875 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC86_07895 ENOG4108D32 Methyltransferase FOC86_07915 ENOG41081I9 integral membrane protein FOC86_07930 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC86_07940 ENOG4105EYF MMPL domain protein FOC86_07965 ENOG4105WCN acetyltransferase FOC86_07985 ENOG4107TSN permease FOC86_08000 ENOG4108QY0 Membrane FOC86_08005 ENOG410900G Protein of unknown function (DUF421) FOC86_08010 ENOG4108QY0 Membrane FOC86_08020 ENOG4107UGY Proline imino-peptidase FOC86_08035 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC86_08045 ENOG4108MEK Metal-binding protein YodA FOC86_08050 ENOG4105CN5 Metallo-Beta-Lactamase FOC86_08055 ENOG4107YZX Universal stress protein FOC86_08060 ENOG4105CHH sulfate transporter FOC86_08070 ENOG4105VUN Transcriptional regulator FOC86_08125 ENOG4105C1Q protoporphyrinogen oxidase FOC86_08135 ENOG41068WN FOC86_08145 ENOG4105VEQ Cold shock protein FOC86_08215 ENOG4107V2S Transcriptional regulator FOC86_08220 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC86_08235 ENOG4105DND Transcriptional regulator FOC86_08240 ENOG4108RPX mosc domain containing protein FOC86_08255 ENOG4105BZ1 (ABC) transporter FOC86_08260 ENOG4105BZ1 (ABC) transporter FOC86_08280 ENOG4108JCI Transcriptional regulator FOC86_08315 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B FOC86_08320 ENOG4108KPJ rna polymerase sigma factor FOC86_08345 ENOG4105F32 YngK protein FOC86_08370 ENOG4105RD7 BadF BadG BcrA BcrD FOC86_08380 ENOG4107STF Involved in phosphonate degradation (By similarity) FOC86_08415 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC86_08425 ENOG4105C1J atp-dependent rna helicase FOC86_08440 ENOG4108RZE Tetr family transcriptional regulator FOC86_08460 ENOG41088CC tellurite resistance protein tehB FOC86_08470 ENOG4108I0C methyltransferase FOC86_08475 ENOG4107RA9 decarboxylase FOC86_08480 ENOG41090HR transcriptional regulator FOC86_08505 ENOG4105CIN aminoacyl-histidine dipeptidase FOC86_08530 ENOG4107RF6 penicillin-binding protein FOC86_08535 ENOG4107RF6 penicillin-binding protein FOC86_08545 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC86_08550 ENOG4105ETE Transcriptional regulator (LacI family FOC86_08555 ENOG4105IE8 Alpha-ketoglutarate permease FOC86_08560 ENOG4105CK5 oxidoreductase FOC86_08585 ENOG4105D2N Aldolase FOC86_08590 ENOG4105DH8 myo-inositol catabolism FOC86_08605 ENOG4105CGH 5'-nucleotidase FOC86_08620 ENOG4105VZ8 Transcriptional regulator FOC86_08650 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity FOC86_08655 ENOG41067SE Tetr family transcriptional regulator FOC86_08660 ENOG4105C5H ABC transporter FOC86_08665 ENOG4105BZU Histidine kinase FOC86_08690 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FOC86_08705 ENOG4105CJ1 ABC, transporter FOC86_08715 ENOG4107Z3H Transcriptional regulator, TetR family FOC86_08730 ENOG4105C1G acyl-Coa dehydrogenase FOC86_08735 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC86_08740 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FOC86_08745 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FOC86_08750 ENOG4105E39 Enoyl-CoA hydratase FOC86_08755 ENOG4107QX3 carboxylase FOC86_08760 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC86_08770 ENOG4105WCN acetyltransferase FOC86_08775 ENOG4105DBI uridine monophosphokinase FOC86_08790 ENOG4105DZ1 carboxypeptidase FOC86_08805 ENOG4105T9C HD domain FOC86_08815 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC86_08860 ENOG4105FQP Beta-lactamase FOC86_08870 ENOG4107Y80 Major Facilitator superfamily FOC86_08890 ENOG4105CUV Homoserine Kinase FOC86_08950 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC86_08960 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FOC86_08970 ENOG4105DK7 lysyl-tRNA synthetase FOC86_09035 ENOG4105D6E homoserine dehydrogenase FOC86_09050 ENOG4105ETU transcriptional activator (TenA FOC86_09115 ENOG4105CNU cell division protein FtsK FOC86_09125 ENOG4108TFU terminase (Small subunit) FOC86_09210 ENOG410667J hydrolase FOC86_09215 ENOG4105BZU Histidine kinase FOC86_09220 ENOG4107RF6 penicillin-binding protein FOC86_09255 ENOG4108HGU Histidine kinase FOC86_09265 ENOG4105RHY Pfam:UPF0157 FOC86_09270 ENOG4105CB2 alcohol dehydrogenase FOC86_09275 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC86_09280 ENOG4105CJN penicillin-binding protein FOC86_09290 ENOG4105FQP Beta-lactamase FOC86_09345 ENOG4107Y80 Major Facilitator superfamily FOC86_09360 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC86_09380 ENOG4107Y9U Membrane FOC86_09415 ENOG4105FCD Major Facilitator FOC86_09430 ENOG4105E09 nadh pyrophosphatase FOC86_09435 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC86_09440 ENOG4108Z4K mutator MutT protein FOC86_09470 ENOG4108XI2 Domain of unknown function (DUF1963) FOC86_09495 ENOG4108NRW Phospholipase, patatin family FOC86_09500 ENOG4105KWG Pfam:DUF1696 FOC86_09535 ENOG4105PKS Excinuclease abc c subunit domain protein FOC86_09575 ENOG4107VFR oxidoreductase FOC86_09620 ENOG4108IUM Glycogen debranching enzyme FOC86_09645 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC86_09655 ENOG4105FDR Membrane FOC86_09715 ENOG4105MSI germination protein ypeb FOC86_09750 ENOG4107Z3H Transcriptional regulator, TetR family FOC86_09780 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOC86_09800 ENOG4105E98 transcriptional regulator DeoR family FOC86_09815 ENOG4107QKR Dehydrogenase FOC86_09825 ENOG4107RUY (E1 component), alpha subunit FOC86_09835 ENOG4105E1F short-chain dehydrogenase reductase FOC86_09840 ENOG4105RHY Pfam:UPF0157 FOC86_09845 ENOG4105DBI uridine monophosphokinase FOC86_09855 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_09880 ENOG4108IJ7 Glycine betaine FOC86_09910 ENOG41082BV acetyltransferase FOC86_09915 ENOG4108M1A Chitin-binding protein FOC86_09930 ENOG4105MSB protein, conserved in bacteria FOC86_09970 ENOG4108Z7F N-acetyltransferase FOC86_09990 ENOG4105EEM helicase FOC86_10010 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC86_10055 ENOG4108M1A Chitin-binding protein FOC86_10075 ENOG4105BZG amino acid carrier protein FOC86_10080 ENOG4105C26 Dehydrogenase FOC86_10085 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC86_10090 ENOG4105CTU Proline racemase FOC86_10095 ENOG4105CTU Proline racemase FOC86_10100 ENOG41080HI glycine oxidase FOC86_10110 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein FOC86_10140 ENOG4107T5V SNARE associated Golgi FOC86_10155 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC86_10160 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FOC86_10175 ENOG4105DTQ mandelate racemase muconate lactonizing FOC86_10215 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) FOC86_10220 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC86_10225 ENOG4105BZU Histidine kinase FOC86_10230 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_10250 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 FOC86_10265 ENOG4105DPN Oligoendopeptidase f FOC86_10275 ENOG4105EPR degv family FOC86_10315 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC86_10320 ENOG4106K7D Major facilitator family transporter FOC86_10340 ENOG4107BMA Transglycosylase associated protein FOC86_10355 ENOG41089UC methyltransferase, type 11 FOC86_10390 ENOG4105CHM Aminotransferase FOC86_10405 ENOG4108ZMI UPF0477 protein FOC86_10420 ENOG4105DVE abc transporter atp-binding protein FOC86_10470 ENOG4105C02 permease FOC86_10480 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC86_10485 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOC86_10490 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FOC86_10515 ENOG4105E09 nadh pyrophosphatase FOC86_10535 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FOC86_10585 ENOG4107VC0 DNA alkylation repair enzyme FOC86_10605 ENOG4108ZCF integral membrane protein FOC86_10610 ENOG4105E0M Sulfatase FOC86_10615 ENOG4105C5H ABC transporter FOC86_10625 ENOG4105EYF MMPL domain protein FOC86_10630 ENOG41082JN Transcriptional regulator FOC86_10660 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC86_10680 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) FOC86_10695 ENOG41069ER domain protein FOC86_10705 ENOG4105CY2 Citrate transporter FOC86_10710 ENOG4105E39 Enoyl-CoA hydratase FOC86_10715 ENOG4105J5T Amp-dependent synthetase and ligase FOC86_10720 ENOG4108JUB Transcriptional regulator FOC86_10735 ENOG4105D4B ABC, transporter FOC86_10745 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FOC86_10755 ENOG4105DKT Transcriptional regulator FOC86_10760 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) FOC86_10770 ENOG41061GT Aldolase FOC86_10795 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FOC86_10830 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_10840 ENOG4107258 Transcriptional regulator FOC86_10850 ENOG4105E0Y RtcB Protein FOC86_10855 ENOG4105ECK Fatty Acid Desaturase FOC86_10860 ENOG4105G6Z alkaline phosphatase FOC86_10870 ENOG4105VMP Transcriptional regulator FOC86_10885 ENOG41090T1 Membrane FOC86_10895 ENOG4108WCX response regulator FOC86_10915 ENOG4105KNA -acetyltransferase FOC86_10940 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_10955 ENOG4105CSH Transporter FOC86_10965 ENOG4105CKK Glycosyl transferase, family 2 FOC86_10980 ENOG4105CKK Glycosyl transferase, family 2 FOC86_10990 ENOG4105C8Y Acetylornithine aminotransferase FOC86_11040 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_11095 ENOG41090AA FOC86_11155 ENOG4108IBT Inherit from COG: transposase FOC86_11175 ENOG4108TVJ Nitroreductase FOC86_11180 ENOG4105FS7 Transcriptional regulator FOC86_11195 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_11215 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC86_11235 ENOG4105C19 ABC transporter FOC86_11265 ENOG4108XET gCN5-related N-acetyltransferase FOC86_11345 ENOG410635A Membrane FOC86_11350 ENOG4105KNA -acetyltransferase FOC86_11355 ENOG4108IQI permease FOC86_11365 ENOG4105F1N DNA alkylation repair FOC86_11395 ENOG4107RF6 penicillin-binding protein FOC86_11430 ENOG4105P4J Allophanate hydrolase, subunit 1 FOC86_11435 ENOG4107258 Transcriptional regulator FOC86_11445 ENOG4106N3A copper homeostasis protein cutc FOC86_11455 ENOG4108ZRV stage ii sporulation protein p FOC86_11460 ENOG4108ZHR arsR family transcriptional regulator FOC86_11470 ENOG4105FDT acyl-CoA dehydrogenase FOC86_11485 ENOG4105DWD nucleoside recognition domain protein FOC86_11525 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOC86_11590 ENOG4105E2A Dehydrogenase FOC86_11600 ENOG4108IJ0 Aspartate ammonia-lyase FOC86_11605 ENOG4105HDK L-asparaginase FOC86_11610 ENOG4108IMY Transcriptional regulator FOC86_11630 ENOG4108B31 Spore germination protein FOC86_11640 ENOG4105BZU Histidine kinase FOC86_11665 ENOG41075H3 AraC family transcriptional regulator FOC86_11675 ENOG4105YWU small acid-soluble spore protein FOC86_11680 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FOC86_11685 ENOG4105CUB amino acid FOC86_11695 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_11710 ENOG4108NHD germination protein FOC86_11715 ENOG4108Q8B Spore germination protein FOC86_11735 ENOG4105CSV Glutaminase FOC86_11770 ENOG4105CGH 5'-nucleotidase FOC86_11775 ENOG4105CH6 catalase FOC86_11785 ENOG4105CHJ isochorismatase hydrolase FOC86_11850 ENOG4105DWP Membrane FOC86_11875 ENOG4108606 TspO/MBR family FOC86_11880 ENOG4105CVP deoxyribo-dipyrimidine photolyase FOC86_11895 ENOG4108TWJ NADH dehydrogenase subunit 5 FOC86_11900 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FOC86_11915 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC86_11955 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC86_11970 ENOG4105E5W Transporter FOC86_11995 ENOG4105C19 ABC transporter FOC86_12010 ENOG4108NEV two component transcriptional regulator, LytTR family FOC86_12035 ENOG4105D6J arsenicaL-resistance protein FOC86_12040 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_12045 ENOG41085FC arsR family transcriptional regulator FOC86_12065 ENOG4107P5I polyketide synthase FOC86_12070 ENOG4108IG5 Transcriptional regulator FOC86_12075 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FOC86_12080 ENOG4108YXU transcriptional regulator AsnC family FOC86_12120 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FOC86_12125 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_12145 ENOG4105IIP Membrane FOC86_12185 ENOG4105K6H D-cysteine desulfhydrase FOC86_12230 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FOC86_12240 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC86_12245 ENOG4105JQZ Methyltransferase FOC86_12260 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOC86_12265 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) FOC86_12280 ENOG4105BZU Histidine kinase FOC86_12290 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC86_12310 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC86_12335 ENOG4108JQ1 Dehydrogenase FOC86_12355 ENOG4108AEY RNA polymerase sigma factor FOC86_12370 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC86_12375 ENOG410874W AraC family transcriptional regulator FOC86_12390 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC86_12560 ENOG4106YAD MORN repeat variant FOC86_12660 ENOG4108ISG Major Facilitator FOC86_12670 ENOG4107MII Sugar-specific transcriptional regulator TrmB FOC86_12675 ENOG4105CZM Major Facilitator FOC86_12690 ENOG4105DA5 (ABC) transporter FOC86_12695 ENOG41069JR FOC86_12705 ENOG4105RXJ FOC86_12710 ENOG4105KPY Small multidrug resistance protein FOC86_12715 ENOG4105KBX Transcriptional regulator, TetR family FOC86_12720 ENOG4107AUC FOC86_12730 ENOG4105CRW Short chain fatty acid transporter FOC86_12740 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC86_12775 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC86_12800 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC86_12825 ENOG4108Z66 YbaK ebsC protein FOC86_12845 ENOG4105KVH Transcriptional regulator FOC86_12850 ENOG4108RCM Nitroreductase FOC86_12870 ENOG4108PSK reductase FOC86_12880 ENOG4105CJ1 ABC, transporter FOC86_12935 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_12940 ENOG4105DKQ ROK family FOC86_12950 ENOG4108UW5 maltose o-acetyltransferase FOC86_12960 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOC86_13000 ENOG4105DMQ Methyltransferase FOC86_13010 ENOG4105EV4 Multidrug resistance protein mdtH FOC86_13040 ENOG4105C37 (CBS) domain FOC86_13055 ENOG4105DDN Pentapeptide repeat-containing protein FOC86_13060 ENOG4105XDF Protein of unknown function (DUF1272) FOC86_13065 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FOC86_13070 ENOG4105CMG Carbohydrate kinase FOC86_13075 ENOG4105C6Z Gluconate FOC86_13080 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC86_13095 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC86_13110 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone FOC86_13125 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FOC86_13130 ENOG4105D4Y metalloprotease FOC86_13165 ENOG4105C44 Serine transporter FOC86_13205 ENOG4108TZY GntR Family Transcriptional Regulator FOC86_13210 ENOG4105D9R oxidoreductase FOC86_13215 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FOC86_13220 ENOG4105KVH Transcriptional regulator FOC86_13225 ENOG4105KVH Transcriptional regulator FOC86_13260 ENOG4105JAB phenazine biosynthesis protein, phzf family FOC86_13270 ENOG4105CHR reductase FOC86_13285 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FOC86_13290 ENOG4105KVH Transcriptional regulator FOC86_13350 ENOG4105KAF membrAne FOC86_13375 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FOC86_13390 ENOG4107YXZ hydrolase, family 25 FOC86_13425 ENOG4105H3G oxidoreductase FOC86_13460 ENOG4105CIS alcohol dehydrogenase FOC86_13470 ENOG4105CBK multidrug resistance protein FOC86_13495 ENOG4108TN2 lmbE family FOC86_13505 ENOG4107R3E Citrate transporter FOC86_13520 ENOG4108MES Periplasmic binding protein FOC86_13525 ENOG4105EHG Permease protein FOC86_13530 ENOG4105DQ5 transport system permease protein FOC86_13535 ENOG4105NX3 Membrane FOC86_13540 ENOG4107ZY0 Phenazine biosynthesis-like protein FOC86_13560 ENOG4107CUJ Protein of unknown function (DUF2690) FOC86_13570 ENOG4107V2S Transcriptional regulator FOC86_13590 ENOG4105C98 muts2 protein FOC86_13600 ENOG4105E5K Alpha-amylase FOC86_13605 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FOC86_13610 ENOG4105DPN Oligoendopeptidase f FOC86_13615 ENOG4108A04 Beta-lactamase FOC86_13640 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC86_13650 ENOG41082BM Transcriptional regulator, arsr family FOC86_13655 ENOG4105CIS alcohol dehydrogenase FOC86_13675 ENOG4105C09 Bile acid FOC86_13680 ENOG4105CQB FAD linked oxidase domain protein FOC86_13705 ENOG4108UT6 Transferase hexapeptide repeat containing protein FOC86_13715 ENOG4105K64 Glycosyl transferase, family 2 FOC86_13720 ENOG4105E39 Enoyl-CoA hydratase FOC86_13730 ENOG4105KT7 mgtC SapB transporter FOC86_13745 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_13750 ENOG41073R8 VanW family FOC86_13760 ENOG4108R1P FOC86_13780 ENOG4105VEQ Cold shock protein FOC86_13800 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC86_13820 ENOG410904N short-chain dehydrogenase reductase FOC86_13830 ENOG4106IQC argininosuccinate lyase FOC86_13845 ENOG4108IA2 Sodium pantothenate symporter FOC86_13855 ENOG4105C26 Dehydrogenase FOC86_13860 ENOG4105CHR reductase FOC86_13870 ENOG4105EWU Squalene--hopene cyclase FOC86_13880 ENOG4105FR1 rard protein FOC86_13885 ENOG410696E Membrane FOC86_13900 ENOG4105D1F ATP-binding protein FOC86_13910 ENOG4108ZAF Molybdopterin FOC86_13915 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC86_13920 ENOG4105D06 uba thif-type nad fad binding protein FOC86_13925 ENOG4105TMB Formate nitrite transporter FOC86_13935 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC86_13940 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FOC86_13950 ENOG4108JB9 formate dehydrogenase FOC86_13955 ENOG4105E1K spore germination protein FOC86_14020 ENOG4107QJT sodium dicarboxylate symporter FOC86_14025 ENOG4108KGH TRANSCRIPTIONal FOC86_14035 ENOG4105EMN RNA polymerase sigma factor FOC86_14045 ENOG4105CIG ABC transporter FOC86_14055 ENOG4105D9R oxidoreductase FOC86_14065 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC86_14070 ENOG4105K4P CoA-binding domain protein FOC86_14075 ENOG4105C0H protease FOC86_14080 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_14090 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOC86_14100 ENOG4105W8X HesB YadR YfhF-family protein FOC86_14130 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC86_14135 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC86_14145 ENOG4108JJA ABC, transporter FOC86_14150 ENOG4108I0Z Aconitate hydratase FOC86_14190 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC86_14210 ENOG4107F3J Amp-dependent synthetase and ligase FOC86_14215 ENOG4107ZYJ bioY protein FOC86_14220 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_14270 ENOG4107AYK membrAne FOC86_14280 ENOG4105BZU Histidine kinase FOC86_14285 ENOG4105FBA Phospholipase Carboxylesterase FOC86_14290 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FOC86_14295 ENOG4105CK7 Sodium proline symporter FOC86_14300 ENOG4105CBC glutamate synthase FOC86_14305 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOC86_14315 ENOG4108VJ1 Transcriptional regulator (CarD family FOC86_14320 ENOG4108903 Formimidoylglutamase FOC86_14345 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) FOC86_14390 ENOG4107QIV Cytochrome c biogenesis protein FOC86_14410 ENOG4105CJ1 ABC, transporter FOC86_14420 ENOG4107RSM transcriptional regulator FOC86_14430 ENOG41067MG lrgb family FOC86_14475 ENOG4105BZ1 (ABC) transporter FOC86_14480 ENOG4105BZ1 (ABC) transporter FOC86_14500 ENOG4105D7V transposase FOC86_14525 ENOG4105CGH 5'-nucleotidase FOC86_14535 ENOG4108SVB resolvase FOC86_14555 ENOG4105K7K Transcriptional regulator FOC86_14560 ENOG4105C5F glutamine synthetase FOC86_14565 ENOG4105KV4 Transcriptional regulator FOC86_14570 ENOG4105CXI aluminum resistance protein FOC86_14575 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC86_14580 ENOG4105EN6 Membrane FOC86_14585 ENOG4106F1P AAA ATPase, central domain protein FOC86_14615 ENOG41069ER domain protein FOC86_14620 ENOG4105DM4 PTS System FOC86_14625 ENOG4105DE4 1-phosphofructokinase FOC86_14630 ENOG4105E98 transcriptional regulator DeoR family FOC86_14635 ENOG4107QW4 alcohol dehydrogenase FOC86_14640 ENOG4108SJC Membrane FOC86_14650 ENOG4105C85 amino acid FOC86_14670 ENOG4105TMB Formate nitrite transporter FOC86_14675 ENOG4105K70 DNA-binding protein FOC86_14685 ENOG4105C59 p-type ATPase FOC86_14690 ENOG410681U heavy metal transport detoxification protein FOC86_14695 ENOG4105VPX protein, conserved in bacteria FOC86_14705 ENOG4105NIV Esterase FOC86_14710 ENOG4105E0A ABC, transporter FOC86_14730 ENOG4105CGK Exodeoxyribonuclease III FOC86_14740 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC86_14745 ENOG4105D03 DNA-3-methyladenine glycosylase II FOC86_14775 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_14780 ENOG4105BZU Histidine kinase FOC86_14825 ENOG4105F0V Cell wall hydrolase FOC86_14830 ENOG4107R6R udp-galactopyranose mutase FOC86_14835 ENOG4105E0M Sulfatase FOC86_14840 ENOG410890F Dynamin family FOC86_14850 ENOG4107QHE Choloylglycine hydrolase FOC86_14880 ENOG4105DQU oxidoreductase, subunit beta FOC86_14885 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FOC86_14890 ENOG4108IGT Dipeptidase FOC86_14895 ENOG4105MCT stage V sporulation protein S FOC86_14900 ENOG4105D48 metallophosphoesterase FOC86_14925 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOC86_14940 ENOG4105XZV Protein of unknown function (DUF3243) FOC86_14945 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FOC86_14965 ENOG4105UIB (ABC) transporter FOC86_14970 ENOG4108JQ9 ABC transporter FOC86_14975 ENOG4105DIH basic membrane FOC86_14980 ENOG4105FDP GntR family transcriptional regulator FOC86_14985 ENOG4107QZI cell division protein FtsK FOC86_14995 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FOC86_15005 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC86_15015 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC86_15020 ENOG4108S0H Dipicolinic acid synthetase, b subunit FOC86_15025 ENOG4105E35 Dipicolinate synthase subunit A FOC86_15035 ENOG4105C1V Peptidase, M16 FOC86_15055 ENOG4105DTN riboflavin biosynthesis protein ribF FOC86_15070 ENOG4105W7A Protein of unknown function (DUF503) FOC86_15080 ENOG4105VHM ribosomal protein FOC86_15085 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FOC86_15090 ENOG4105CHV Transcription elongation factor NusA FOC86_15100 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC86_15110 ENOG4105DZP Membrane-associated zinc metalloprotease FOC86_15120 ENOG4105KNE Phosphatidate cytidylyltransferase FOC86_15165 ENOG4108HE4 integrase family FOC86_15175 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOC86_15180 ENOG4105C79 DNA protecting protein DprA FOC86_15185 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOC86_15200 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FOC86_15225 ENOG4105VB6 UPF0109 protein FOC86_15245 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOC86_15250 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FOC86_15265 ENOG4105CHR reductase FOC86_15270 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC86_15285 ENOG4105CB5 ATP-dependent DNA helicase recG FOC86_15290 ENOG4105DP4 dak2 domain fusion protein ylov FOC86_15295 ENOG4108ZAA Alkaline-shock protein FOC86_15310 ENOG4105FJ0 thiamine FOC86_15315 ENOG4105DJV ribulose-phosphate 3-epimerase FOC86_15320 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FOC86_15325 ENOG4105D9P serine threonine protein kinase FOC86_15330 ENOG4108ZF3 Phosphatase FOC86_15340 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FOC86_15350 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC86_15355 ENOG4105C25 Primosomal protein n' FOC86_15360 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOC86_15380 ENOG4105DSJ YicC domain protein FOC86_15395 ENOG4105DC7 peptidase M24 FOC86_15480 ENOG4105C34 Pseudouridine synthase FOC86_15505 ENOG4105DBK s4 domain protein FOC86_15510 ENOG41067XK integral membrane protein FOC86_15520 ENOG4105DFA alanine racemase domain protein FOC86_15525 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOC86_15530 ENOG4105WR5 sporulation protein, YlmC YmxH family FOC86_15540 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_15550 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOC86_15555 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOC86_15560 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FOC86_15575 ENOG4105CNI cell division protein FtsW FOC86_15590 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC86_15595 ENOG4105CJN penicillin-binding protein FOC86_15600 ENOG4105CJN penicillin-binding protein FOC86_15605 ENOG41068DC Essential cell division protein (By similarity) FOC86_15640 ENOG4105KNH Nucleic acid-binding protein FOC86_15650 ENOG41063PX domain protein FOC86_15655 ENOG4105D78 K07001 NTE family protein FOC86_15660 ENOG4105H20 Sporulation integral membrane protein YlbJ FOC86_15670 ENOG4106H78 methyltransferase FOC86_15690 ENOG4107TB6 phosphoglycerate mutase FOC86_15705 ENOG4106UY4 Inherit from COG: Scp-like extracellular FOC86_15755 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FOC86_15760 ENOG4105CNI cell division protein FtsW FOC86_15780 ENOG4108IAB Phoh family FOC86_15800 ENOG4105QA2 FOC86_15805 ENOG4105CI3 gtp-binding protein typa FOC86_15815 ENOG4105ECY inositol monophosphatase FOC86_15835 ENOG4105CXN decarboxylase FOC86_15885 ENOG4105CPP Dehydrogenase, E1 component FOC86_15900 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC86_15905 ENOG4108X4Q Hydrolase FOC86_15915 ENOG4105CN5 Metallo-Beta-Lactamase FOC86_15920 ENOG4107ZYR domain protein FOC86_15955 ENOG4108XRC Protein of unknown function (DUF458) FOC86_15965 ENOG4107IN1 Protein of unknown function (DUF1797) FOC86_15980 ENOG4105EPM Diguanylate phosphodiesterase FOC86_15985 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FOC86_16000 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOC86_16010 ENOG4105UIN FOC86_16065 ENOG4108HGU Histidine kinase FOC86_16075 ENOG4105CHM Aminotransferase FOC86_16080 ENOG4105FKQ transcriptional regulator FOC86_16085 ENOG4105EG2 ABC transporter, permease FOC86_16095 ENOG4107FKK extracellular solute-binding protein family 1 FOC86_16105 ENOG4105CG3 alpha amylase, catalytic region FOC86_16155 ENOG4105CHU acetyl-coa acetyltransferase FOC86_16190 ENOG4105K7K Transcriptional regulator FOC86_16195 ENOG4105DTD Dehydrogenase FOC86_16215 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOC86_16255 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC86_16260 ENOG4106TD9 Diguanylate cyclase FOC86_16280 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOC86_16295 ENOG4105CID antiterminator FOC86_16315 ENOG4105CE4 GlcNAc 6-P deacetylase FOC86_16350 ENOG4107ZE5 PPIases accelerate the folding of proteins FOC86_16355 ENOG4105PTM secreted protein FOC86_16360 ENOG4105J7I hydrolase FOC86_16370 ENOG4105G6R Stage v sporulation protein ae FOC86_16380 ENOG4105CZ3 stage V sporulation protein ad FOC86_16385 ENOG41090VF Stage v sporulation protein ac FOC86_16405 ENOG4105C8J )-transporter FOC86_16410 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_16420 ENOG41082AN stage II sporulation protein FOC86_16425 ENOG4105DZ1 carboxypeptidase FOC86_16430 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC86_16435 ENOG4105DVE abc transporter atp-binding protein FOC86_16470 ENOG4105D7N magnesium and cobalt transport protein CorA FOC86_16495 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC86_16505 ENOG4105I3K Ferric uptake regulator, Fur family FOC86_16510 ENOG4105MZ9 stage II sporulation protein m FOC86_16535 ENOG4105CPC Aldo Keto reductase FOC86_16545 ENOG4105RHY Pfam:UPF0157 FOC86_16565 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC86_16575 ENOG4105ETE Transcriptional regulator (LacI family FOC86_16580 ENOG4108YM7 Gcn5-related n-acetyltransferase FOC86_16600 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC86_16605 ENOG4108R6K riboflavin synthase, subunit alpha FOC86_16630 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC86_16635 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC86_16650 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC86_16660 ENOG4105DFD Na H antiporter FOC86_16665 ENOG4105CGH 5'-nucleotidase FOC86_16755 ENOG4108IXY short-chain dehydrogenase reductase FOC86_16760 ENOG41069FQ Metallo-beta-lactamase superfamily FOC86_16765 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_16770 ENOG4105EJQ L-serine dehydratase FOC86_16795 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC86_16805 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FOC86_16810 ENOG4105D9U N-acetyltransferase FOC86_16825 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FOC86_16830 ENOG4108QEG Membrane FOC86_16835 ENOG4105CDA abc transporter atp-binding protein FOC86_16840 ENOG4105E5Q amino acid AbC transporter FOC86_16845 ENOG4108HW3 (ABC) transporter FOC86_16855 ENOG4105G7B Protein of unknown function (DUF2992) FOC86_16860 ENOG4105E09 nadh pyrophosphatase FOC86_16870 ENOG4105C7S Dehydrogenase FOC86_16875 ENOG4105CPP Dehydrogenase, E1 component FOC86_16895 ENOG4107RDP Dehydrogenase FOC86_16905 ENOG4108JUB Transcriptional regulator FOC86_16915 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC86_16930 ENOG4107QQR Sporulation FOC86_16935 ENOG4105S1Z Stage IV sporulation protein B FOC86_16940 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOC86_16950 ENOG4105DX0 Hemolysin A FOC86_16960 ENOG4105CTB Polyprenyl synthetase FOC86_16985 ENOG4108ZSR alkaline shock protein FOC86_16990 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC86_17015 ENOG410644B Stage III sporulation protein af FOC86_17025 ENOG4105KQ4 Stage iii sporulation protein ad FOC86_17030 ENOG4108CQH stage III sporulation protein AC FOC86_17035 ENOG4105KR5 Stage iii sporulation protein FOC86_17040 ENOG4105CD2 stage iii sporulation protein aa FOC86_17065 ENOG4105DC7 peptidase M24 FOC86_17080 ENOG4105CBJ Metal-dependent enzyme FOC86_17090 ENOG4107YBY Hydrolase FOC86_17125 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FOC86_17130 ENOG4105WZW rhodanese family FOC86_17150 ENOG41080TC multidrug resistance protein FOC86_17190 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC86_17220 ENOG4105C0D helicase FOC86_17340 ENOG4105C3R Methionine synthase FOC86_17350 ENOG4105C28 cystathionine FOC86_17355 ENOG4105C28 cystathionine FOC86_17375 ENOG4105C5X domain protein FOC86_17385 ENOG4105DKQ ROK family FOC86_17395 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOC86_17410 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOC86_17420 ENOG4105E2Z phosphate ABC transporter (Permease FOC86_17425 ENOG4105C8U phosphate abc transporter FOC86_17430 ENOG4105PWN phosphate abc transporter FOC86_17440 ENOG4107RF6 penicillin-binding protein FOC86_17450 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC86_17475 ENOG4105N80 Ferric uptake regulator, Fur family FOC86_17485 ENOG4105FDK ABC transporter FOC86_17490 ENOG4108JYZ YitT family FOC86_17495 ENOG41069ZM Protein of unknown function (DUF2624) FOC86_17520 ENOG4105EGD dinuclear metal center protein, YbgI family FOC86_17535 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_17540 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOC86_17570 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FOC86_17575 ENOG4105KG3 cytidine deaminase FOC86_17580 ENOG4107YR5 Diacylglycerol kinase FOC86_17590 ENOG4105CTJ Metal Dependent Phosphohydrolase FOC86_17595 ENOG4105C9A Phoh family FOC86_17605 ENOG41068P3 sporulation protein YqfC FOC86_17610 ENOG4105KTH gatB Yqey FOC86_17620 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC86_17625 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOC86_17655 ENOG4105CSA Coproporphyrinogen iii oxidase FOC86_17660 ENOG4105KVH Transcriptional regulator FOC86_17685 ENOG4105TQK DNA polymerase iii, delta' subunit FOC86_17695 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC86_17700 ENOG4108UK2 deaminase FOC86_17705 ENOG4105KQC Competence protein FOC86_17715 ENOG4105DXX methyltransferase FOC86_17725 ENOG4108WF2 Metal Dependent Phosphohydrolase FOC86_17735 ENOG410812S Rna-binding protein FOC86_17745 ENOG4105CQW ribosome biogenesis GTPase YqeH FOC86_17750 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FOC86_17765 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_17795 ENOG4108TVJ Nitroreductase FOC86_17810 ENOG4105G6Z alkaline phosphatase FOC86_17820 ENOG4108MUZ hydrolase FOC86_17855 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC86_17860 ENOG4105MIR Phenylalanine 4-monooxygenase FOC86_17870 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC86_17910 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC86_17915 ENOG4108V5C ABC transporter FOC86_17925 ENOG4105C0A alcohol dehydrogenase FOC86_17930 ENOG4105C28 cystathionine FOC86_17960 ENOG4107XRG penicillin-binding protein FOC86_17975 ENOG4105CFP Peptidase U32 FOC86_17980 ENOG4105XYU peptidase (U32 family) FOC86_17990 ENOG4105HHA aminodeoxychorismate lyase FOC86_18020 ENOG4105C02 permease FOC86_18035 ENOG41060CR FOC86_18040 ENOG4105C7H Helicase, RecD TraA family FOC86_18055 ENOG4105C3J Cysteine desulfurase FOC86_18065 ENOG4105D1H recombination factor protein RarA FOC86_18070 ENOG4108VCI transcription factor, rsfa family FOC86_18075 ENOG4105CUZ uba thif-type nad fad binding protein FOC86_18100 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC86_18110 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC86_18115 ENOG41076HS cation diffusion facilitator family transporter FOC86_18120 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOC86_18130 ENOG4105CKP Polysaccharide Biosynthesis Protein FOC86_18135 ENOG4108QG2 Membrane FOC86_18145 ENOG4105VIE preprotein translocase, subunit YajC FOC86_18160 ENOG41061AI Protein of unknown function (DUF2905) FOC86_18175 ENOG4108HUF Transporter FOC86_18185 ENOG4108IPJ Membrane FOC86_18190 ENOG41082BM Transcriptional regulator, arsr family FOC86_18215 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOC86_18220 ENOG4108IYU L-aspartate oxidase FOC86_18235 ENOG4108RPX mosc domain containing protein FOC86_18240 ENOG4105CQC Prephenate dehydratase FOC86_18260 ENOG4105EWM Histidine kinase FOC86_18285 ENOG4105X36 (ribosomal) protein FOC86_18295 ENOG4105C03 ribonuclease FOC86_18310 ENOG4107QMS site-determining protein FOC86_18330 ENOG4105DFF Rod shape-determining protein mreb FOC86_18350 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOC86_18365 ENOG41068KH stage VI sporulation protein D FOC86_18375 ENOG4105D52 delta-aminolevulinic acid dehydratase FOC86_18400 ENOG4105K56 Transcriptional regulator FOC86_18420 ENOG4108IUQ atp-dependent protease FOC86_18450 ENOG4108QCI YvbH-like oligomerisation region FOC86_18480 ENOG4105M59 Phosphodiesterase, mj0936 family FOC86_18495 ENOG4108XJQ germination protein FOC86_18505 ENOG4108PCX Major Facilitator FOC86_18515 ENOG4105KBX Transcriptional regulator, TetR family FOC86_18530 ENOG4105PFC Transcriptional regulator FOC86_18545 ENOG4105DZC cytosine deaminase FOC86_18550 ENOG4105DZC cytosine deaminase FOC86_18555 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC86_18560 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_18575 ENOG4108JQ7 (ABC) transporter FOC86_18580 ENOG4108HRK Histidine kinase FOC86_18585 ENOG4105DY9 regulatoR FOC86_18595 ENOG41067S9 phage shock protein C, PspC FOC86_18600 ENOG4108JCI Transcriptional regulator FOC86_18610 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC86_18615 ENOG4108Z40 Transcriptional regulator FOC86_18620 ENOG4105RHA ABC transporter, permease FOC86_18625 ENOG4108IUX (ABC) transporter FOC86_18630 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family FOC86_18635 ENOG4105ER2 Ompa motb domain protein FOC86_18640 ENOG4105E14 MotA TolQ exbB proton channel FOC86_18645 ENOG4108VXD carboxy-peptidase FOC86_18655 ENOG4105E33 succinate dehydrogenase FOC86_18665 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FOC86_18680 ENOG4105K63 Thioredoxin FOC86_18685 ENOG4105C10 Electron transfer flavoprotein FOC86_18690 ENOG4105BZJ Electron transfer flavoprotein FOC86_18695 ENOG41060WC Enoyl-CoA hydratase FOC86_18700 ENOG4107Z3H Transcriptional regulator, TetR family FOC86_18705 ENOG4105CEY Amp-dependent synthetase and ligase FOC86_18715 ENOG4105J76 Periplasmic binding protein FOC86_18720 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC86_18760 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_18775 ENOG4105DR4 Methyltransferase FOC86_18790 ENOG4105KFN sortase, SrtB family FOC86_18795 ENOG4105E0A ABC, transporter FOC86_18810 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) FOC86_18815 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) FOC86_18825 ENOG4105FE9 pseudouridine synthase FOC86_18835 ENOG4105DCG PHP domain protein FOC86_18885 ENOG4108RWN rrna methyltransferase FOC86_18905 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_18910 ENOG4105CW7 secretion protein, HlyD family FOC86_18915 ENOG4108JGH Tetr family transcriptional regulator FOC86_18920 ENOG4105CN9 Peptidase m42 family protein FOC86_18945 ENOG4105C22 threonyL-tRNA synthetase FOC86_18950 ENOG4108TDW sporulation protein YtxC FOC86_18975 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOC86_18995 ENOG4105C2M dna polymerase I FOC86_19000 ENOG4105BZU Histidine kinase FOC86_19005 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_19020 ENOG4108HMX isocitrate dehydrogenase (NADP) FOC86_19025 ENOG4105BZN citrate synthase FOC86_19035 ENOG4108REF Sporulation integral membrane protein ytvi FOC86_19040 ENOG4105FS0 cytoplasmic membrane protein FOC86_19065 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC86_19070 ENOG4105C6K Malic enzyme FOC86_19075 ENOG4105C0B DNA polymerase III (alpha subunit) FOC86_19080 ENOG4105VV2 FOC86_19090 ENOG4105SFS phosphoesterase RecJ domain protein FOC86_19130 ENOG4105DC7 peptidase M24 FOC86_19175 ENOG4105Z7P Acetyltransferase (GNAT) family FOC86_19180 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC86_19200 ENOG4107YZX Universal stress protein FOC86_19240 ENOG4108JYZ YitT family FOC86_19270 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOC86_19275 ENOG4105KBJ sporulation protein ytfj FOC86_19290 ENOG4105EFZ amidohydrolase FOC86_19300 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC86_19325 ENOG4106KR7 LysR family Transcriptional regulator FOC86_19335 ENOG4105U5Y Transcriptional regulator FOC86_19345 ENOG4105C28 cystathionine FOC86_19385 ENOG4105F1V Acetoin utilization protein FOC86_19390 ENOG4105W87 Cbs domain FOC86_19395 ENOG4105DGU Histone deacetylase FOC86_19410 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_19420 ENOG4107SNB ankyrin repeat protein YahD FOC86_19425 ENOG4105EP9 oxidoreductase FOC86_19455 ENOG4105ETE Transcriptional regulator (LacI family FOC86_19475 ENOG4105C88 aminopeptidase FOC86_19500 ENOG4105K7K Transcriptional regulator FOC86_19530 ENOG4108VDD TRNA binding domain protein FOC86_19560 ENOG4105C8F Beta-lactamase domain protein FOC86_19575 ENOG4108V15 phosphotransferase enzyme family FOC86_19580 ENOG4108IUM Glycogen debranching enzyme FOC86_19590 ENOG4107QSE Dipeptidase FOC86_19595 ENOG4105YW5 deoR family transcriptional regulator FOC86_19610 ENOG4105CBX hi0933 family FOC86_19645 ENOG4108VJ1 Transcriptional regulator (CarD family FOC86_19650 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC86_19670 ENOG4108ZAF Molybdopterin FOC86_19675 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FOC86_19680 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC86_19690 ENOG4105D06 uba thif-type nad fad binding protein FOC86_19695 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC86_19715 ENOG41085GJ domain protein FOC86_19725 ENOG4105DWV Homoserine O-trans-acetylase FOC86_19735 ENOG4108B31 Spore germination protein FOC86_19765 ENOG410605W Major Facilitator FOC86_19770 ENOG4107S91 Sodium hydrogen exchanger FOC86_19775 ENOG4105NCW Trka-c domain protein FOC86_19790 ENOG4105C19 ABC transporter FOC86_19810 ENOG4105N5T Radical SAM Protein FOC86_19820 ENOG4105CIG ABC transporter FOC86_19865 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOC86_19870 ENOG4108Z0R Transferase FOC86_19875 ENOG4105YVM Phosphoesterase, PA-phosphatase related FOC86_19880 ENOG4105BZF Glycosyl transferase (Group 1 FOC86_19890 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOC86_19905 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC86_19950 ENOG4105EGD dinuclear metal center protein, YbgI family FOC86_19955 ENOG4105BZU Histidine kinase FOC86_19960 ENOG4105BZU Histidine kinase FOC86_19965 ENOG4107S9D Alpha beta hydrolase FOC86_19970 ENOG4107T7U Sulfatase FOC86_19985 ENOG4105D2X ABC transporter substrate-binding protein FOC86_19995 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FOC86_20055 ENOG4108V2W Carbonate dehydratase FOC86_20060 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC86_20065 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC86_20115 ENOG41087YS Phage shock protein A FOC86_20145 ENOG4105BZU Histidine kinase FOC86_20150 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_20175 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC86_20180 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FOC86_20200 ENOG4105C19 ABC transporter FOC86_20215 ENOG4107ZTW SNARE associated Golgi FOC86_20225 ENOG41063TF transcriptional regulator (AraC FOC86_20240 ENOG4105C19 ABC transporter FOC86_20245 ENOG41086D8 Transcriptional regulator FOC86_20315 ENOG41069H0 dihydroorotase EC 3.5.2.3 FOC86_20335 ENOG4105DTQ mandelate racemase muconate lactonizing FOC86_20345 ENOG4108IPT Naphthoate synthase FOC86_20350 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FOC86_20360 ENOG4105E4F Isochorismate synthase FOC86_20365 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC86_20375 ENOG4105VEQ Cold shock protein FOC86_20435 ENOG4105JVQ RNA Polymerase FOC86_20530 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FOC86_20565 ENOG4105KT7 mgtC SapB transporter FOC86_20570 ENOG4107PBV potassium channel FOC86_20585 ENOG4105WG9 Conserved Protein FOC86_20595 ENOG4105CHM Aminotransferase FOC86_20600 ENOG4108ZB6 transcriptional regulator AsnC family FOC86_20605 ENOG4105C5I Dehydrogenase FOC86_20610 ENOG4108MUZ hydrolase FOC86_20620 ENOG4105C87 Aminotransferase class I and II FOC86_20635 ENOG4105Y38 Kinase-associated protein B FOC86_20645 ENOG4107R3E Citrate transporter FOC86_20665 ENOG4105KA0 thioesterase Superfamily protein FOC86_20685 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC86_20705 ENOG41069ER domain protein FOC86_20725 ENOG4105CEP NADH dehydrogenase FOC86_20755 ENOG4105EWC Purine nucleoside phosphorylase FOC86_20765 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FOC86_20790 ENOG4108JJA ABC, transporter FOC86_20795 ENOG4105C4B ABC transporter, permease FOC86_20800 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC86_20825 ENOG41083MR nifu domain-containing protein FOC86_20840 ENOG4108W5N phosphatidylglycerophosphatase a FOC86_20855 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC86_20860 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC86_20870 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOC86_20885 ENOG4105CBT Fructose-1,6-bisphosphatase FOC86_20905 ENOG4105MMD transcriptional regulator FOC86_20910 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FOC86_20915 ENOG4107TXC Transcriptional regulator FOC86_20920 ENOG41090T1 Membrane FOC86_20945 ENOG4105FAA peptidase M23 FOC86_20955 ENOG4105KZD Domain of unknown function (DUF1805) FOC86_20960 ENOG4107R8B 5'-nucleotidase FOC86_20965 ENOG4105DIW FeS assembly protein SUFB FOC86_20970 ENOG4108UNV SUF system FeS assembly protein, NifU family FOC86_20975 ENOG4105C9B Cysteine desulfurase FOC86_20980 ENOG4105JRK feS assembly protein SufD FOC86_20985 ENOG4105C3K feS assembly ATPase SufC FOC86_20990 ENOG4105D01 (LipO)protein FOC86_20995 ENOG4105D01 (LipO)protein FOC86_21000 ENOG4108UMI ABC transporter, permease FOC86_21030 ENOG41080E8 Transcriptional regulator, Spx MgsR family FOC86_21090 ENOG4108IMY Transcriptional regulator FOC86_21105 ENOG4108W8B Beta-lactamase domain protein FOC86_21110 ENOG4105C1G acyl-Coa dehydrogenase FOC86_21115 ENOG4105CHU acetyl-coa acetyltransferase FOC86_21130 ENOG4105DZ1 carboxypeptidase FOC86_21150 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_21170 ENOG4108SUT Major Facilitator Superfamily FOC86_21175 ENOG4107R7I amino acid FOC86_21185 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC86_21195 ENOG4107AYK membrAne FOC86_21235 ENOG4107ZTW SNARE associated Golgi FOC86_21245 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC86_21250 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_21255 ENOG4105BZU Histidine kinase FOC86_21275 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_21280 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_21285 ENOG4105VG1 fes assembly suf system protein FOC86_21290 ENOG4105D4Y metalloprotease FOC86_21310 ENOG4107S91 Sodium hydrogen exchanger FOC86_21315 ENOG4105NCW Trka-c domain protein FOC86_21325 ENOG4108RMU ferritin dps family protein FOC86_21340 ENOG4108URH decarboxylase FOC86_21360 ENOG4105D9N nucleoside FOC86_21365 ENOG4105D9N nucleoside FOC86_21375 ENOG4108RYK Nad-dependent epimerase dehydratase FOC86_21390 ENOG4105CV8 reductase FOC86_21395 ENOG4105F27 Major Facilitator FOC86_21400 ENOG4105KVH Transcriptional regulator FOC86_21435 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_21465 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC86_21485 ENOG4108IPW abc transporter atp-binding protein FOC86_21490 ENOG4105CM4 permease protein FOC86_21505 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_21515 ENOG4105C19 ABC transporter FOC86_21535 ENOG4107ZTW SNARE associated Golgi FOC86_21545 ENOG4105DHF Membrane FOC86_21565 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOC86_21575 ENOG4105XZU Preprotein translocase, subunit SecG FOC86_21580 ENOG41067MG lrgb family FOC86_21630 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_21650 ENOG41090VF Stage v sporulation protein ac FOC86_21655 ENOG4105CZ3 stage V sporulation protein ad FOC86_21670 ENOG4105H67 Protein of unknown function (DUF421) FOC86_21680 ENOG4105KRI phosphocarrier protein (HPr FOC86_21690 ENOG4105CHW UPF0052 protein FOC86_21700 ENOG4108Z4K mutator MutT protein FOC86_21710 ENOG4105C3M thioredoxin reductase FOC86_21720 ENOG4108S4C acetyltransferase FOC86_21740 ENOG41086DT Membrane protein of unknown function FOC86_21750 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC86_21770 ENOG4107TXC Transcriptional regulator FOC86_21800 ENOG4105HMI Membrane FOC86_21805 ENOG4105DUM transcriptional regulator, lysR family FOC86_21815 ENOG4108WS4 fmn reductase FOC86_21830 ENOG4105BZ1 (ABC) transporter FOC86_21840 ENOG4105CN1 protease FOC86_21845 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOC86_21850 ENOG4105CAK Cell division ATP-binding protein ftsE FOC86_21870 ENOG4105MS2 ribosomal subunit Interface protein FOC86_21875 ENOG4105VEQ Cold shock protein FOC86_21880 ENOG41081UC Inherit from COG: Competence protein FOC86_21890 ENOG4105K4H Nlp p60 protein FOC86_21895 ENOG4105KVH Transcriptional regulator FOC86_21905 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOC86_21910 ENOG4108KGH TRANSCRIPTIONal FOC86_21915 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC86_21920 ENOG4105C6Y Udp-glucose 6-dehydrogenase FOC86_21925 ENOG4105ESV Glycosyl transferase, family 4 FOC86_21935 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOC86_21955 ENOG4105F8D glycoside hydrolase family 4 FOC86_21960 ENOG4105VCP PTS System FOC86_21965 ENOG4105CK1 PTS System FOC86_21975 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FOC86_21995 ENOG4105VCP PTS System FOC86_22005 ENOG4105VZJ PTS System FOC86_22020 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC86_22025 ENOG4105ECB domain protein FOC86_22030 ENOG4107RSM transcriptional regulator FOC86_22070 ENOG4105DAA L-lactate FOC86_22080 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) FOC86_22090 ENOG4105E0M Sulfatase FOC86_22115 ENOG4107R8N Glycosyl transferase, family 2 FOC86_22120 ENOG4105C94 Transporter FOC86_22125 ENOG41069ER domain protein FOC86_22150 ENOG4105KBK Zinc finger, swim domain protein FOC86_22155 ENOG4105C0D helicase FOC86_22185 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC86_22200 ENOG4107RBB ABC transporter, permease FOC86_22205 ENOG4105C19 ABC transporter FOC86_22225 ENOG4105CXY transporter FOC86_22240 ENOG4105BZU Histidine kinase FOC86_22245 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_22250 ENOG4105CMR udp-glucose 4-epimerase FOC86_22265 ENOG4105D7W serine acetyltransferase FOC86_22270 ENOG4107QQG Dehydrogenase FOC86_22280 ENOG4105CJR Integral membrane protein (MviN FOC86_22300 ENOG4105D3Q Sugar transferase FOC86_22305 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC86_22310 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FOC86_22315 ENOG4107YJ4 chain length determinant protein FOC86_22320 ENOG4105HTX biosynthesis protein FOC86_22325 ENOG4107YJ4 chain length determinant protein FOC86_22340 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FOC86_22350 ENOG4105FRN stage II sporulation protein FOC86_22365 ENOG4105DY9 regulatoR FOC86_22385 ENOG4106778 Protein of unknown function (DUF1146) FOC86_22390 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC86_22395 ENOG4105C8S subunit m FOC86_22400 ENOG4105D65 subunit l FOC86_22430 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC86_22445 ENOG4105BZU Histidine kinase FOC86_22495 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FOC86_22500 ENOG41062M3 atp synthase FOC86_22530 ENOG4108YZG isomerase FOC86_22545 ENOG4108VGI doxx family FOC86_22550 ENOG4107XC4 flavin reductase domain protein, FMN-binding FOC86_22570 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC86_22580 ENOG4108ZXQ stage ii sporulation protein r FOC86_22585 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC86_22605 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FOC86_22610 ENOG4105CBT Fructose-1,6-bisphosphatase FOC86_22650 ENOG4105C1G acyl-Coa dehydrogenase FOC86_22655 ENOG4105C1G acyl-Coa dehydrogenase FOC86_22660 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC86_22670 ENOG4105DF6 Fe-S oxidoreductase FOC86_22685 ENOG4105BZU Histidine kinase FOC86_22710 ENOG4105BZU Histidine kinase FOC86_22715 ENOG4105KCT ABC transporter FOC86_22720 ENOG4108M15 ABC transporter FOC86_22725 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FOC86_22735 ENOG4105IIU Aminopeptidase FOC86_22755 ENOG4105DU6 RNA polymerase FOC86_22765 ENOG410684U Domain of unknown function (DUF1934) FOC86_22785 ENOG4105CYW agmatinase FOC86_22795 ENOG4105DXB Major Facilitator superfamily FOC86_22800 ENOG4107SWG transcriptional regulator MERR family FOC86_22805 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC86_22810 ENOG4105BZ4 penicillin-binding protein FOC86_22815 ENOG4108XFG YwhD family FOC86_22820 ENOG4108Z4T Peptidase M50 FOC86_22825 ENOG41069HH 4-oxalocrotonate tautomerase FOC86_22830 ENOG4105DCI Phosphohydrolase FOC86_22835 ENOG4108MES Periplasmic binding protein FOC86_22840 ENOG4105E0A ABC, transporter FOC86_22845 ENOG4105EHG Permease protein FOC86_22850 ENOG4105DQ5 transport system permease protein FOC86_22860 ENOG4108VCI transcription factor, rsfa family FOC86_22875 ENOG4108IJ2 phosphate acetyltransferase FOC86_22890 ENOG4108VKI Cell wall hydrolase FOC86_22910 ENOG4107SVH Potassium channel protein FOC86_22920 ENOG410667J hydrolase FOC86_22925 ENOG4105VCH membrane FOC86_22935 ENOG4108TU7 Inherit from COG: (ABC) transporter FOC86_22940 ENOG4105CJ1 ABC, transporter FOC86_22945 ENOG41090WU lipolytic protein G-D-S-L family FOC86_22960 ENOG4105D6E homoserine dehydrogenase FOC86_22980 ENOG4108Y4K DNA-binding transcriptional activator FOC86_22990 ENOG4105WH1 Two component transcriptional regulator luxr family FOC86_22995 ENOG4105BZU Histidine kinase FOC86_23000 ENOG4105DWF phosphomethylpyrimidine kinase FOC86_23005 ENOG4105BZU Histidine kinase FOC86_23010 ENOG4105VCD cytoplasmic protein FOC86_23015 ENOG4105D22 carbon starvation protein FOC86_23020 ENOG4105DY9 regulatoR FOC86_23025 ENOG41079KZ Major Facilitator Superfamily FOC86_23045 ENOG4105EN6 Membrane FOC86_23050 ENOG4106YBV Methyl-accepting chemotaxis FOC86_23060 ENOG4108S4H thioesterase Superfamily protein FOC86_23065 ENOG4105K64 Glycosyl transferase, family 2 FOC86_23075 ENOG4105C5H ABC transporter FOC86_23095 ENOG4105CKK Glycosyl transferase, family 2 FOC86_23100 ENOG41067SE Tetr family transcriptional regulator FOC86_23110 ENOG4105E0X reductase FOC86_23120 ENOG4106F5Q Membrane FOC86_23135 ENOG4105DY9 regulatoR FOC86_23140 ENOG4108HRK Histidine kinase FOC86_23145 ENOG4107RGD Major Facilitator superfamily FOC86_23160 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC86_23170 ENOG4105IW1 AmiS UreI transporter FOC86_23180 ENOG4105CMR udp-glucose 4-epimerase FOC86_23185 ENOG4108UT2 hemolysin iii FOC86_23200 ENOG4105C1J atp-dependent rna helicase FOC86_23215 ENOG4105DPN Oligoendopeptidase f FOC86_23235 ENOG4105C0H protease FOC86_23240 ENOG4105Q2H domain protein FOC86_23255 ENOG4105BZU Histidine kinase FOC86_23260 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_23290 ENOG4105CDU Replicative dna helicase FOC86_23300 ENOG4105BZR domain protein FOC86_23305 ENOG4108XMW Membrane FOC86_23315 ENOG4108UUM single-stranded DNA-binding protein FOC86_23325 ENOG4105C3G gtp-binding protein FOC86_23330 ENOG4105VDK protein, conserved in bacteria FOC86_23335 ENOG4105D8X mechanosensitive ion channel FOC86_23340 ENOG4108ZDA Sporulation protein YyaC FOC86_23345 ENOG4105FA0 parb-like partition protein FOC86_23350 ENOG4107QJE Chromosome Partitioning Protein FOC86_23380 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC86_23400 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC86_23405 ENOG410848D S4 domain protein YaaA FOC86_23420 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC86_23455 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOC86_23490 ENOG4105ZMH deoxynucleoside kinase FOC86_23500 ENOG4105GTG Isochorismatase FOC86_23505 ENOG4108Z6B deaminase FOC86_23515 ENOG4105C6E dna polymerase iii FOC86_23535 ENOG41067KS pro-sigma K processing FOC86_23570 ENOG4105CXN decarboxylase FOC86_23580 ENOG4105FA2 dna polymerase iii FOC86_23585 ENOG4105MA4 psp1 domain protein FOC86_23595 ENOG41060K3 Methyltransferase FOC86_23605 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOC86_23610 ENOG4105KRN Transcriptional regulator, abrb family FOC86_23620 ENOG4105F8V Hydrolase, tatD family FOC86_23625 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) FOC86_23635 ENOG4105XFA sporulation peptidase YabG FOC86_23640 ENOG4105W42 Veg protein FOC86_23655 ENOG4105DFT pur operon repressor FOC86_23660 ENOG4105KME endoribonuclease L-psp FOC86_23690 ENOG4108JA2 transcriptioN-repair coupling factor FOC86_23695 ENOG4108M14 stage v sporulation protein t FOC86_23705 ENOG4108IY2 MazG family FOC86_23710 ENOG41082I2 s4 domain protein FOC86_23715 ENOG4105VYY sporulation protein yabp FOC86_23730 ENOG41060GV RNA binding s1 domain protein FOC86_23755 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC86_23760 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOC86_23775 ENOG4105C6T cysteine synthase FOC86_23780 ENOG4105CRQ synthase (Component I) FOC86_23785 ENOG4105DDQ anthranilate synthase FOC86_23790 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FOC86_23795 ENOG4105EEI dihydropteroate synthase FOC86_23800 ENOG4105KRF dihydroneopterin aldolase FOC86_23805 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOC86_23815 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOC86_23905 ENOG4108Z0C Uvrb UvrC protein FOC86_23920 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOC86_23930 ENOG4105CTP PilT protein domain protein FOC86_23950 ENOG4105D7W serine acetyltransferase FOC86_23965 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOC86_23970 ENOG4105M0M Tetracycline resistance protein FOC86_23975 ENOG4105QIV RNA polymerase FOC86_23990 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOC86_24015 ENOG4107Y49 methyltransferase FOC86_24030 ENOG4105XPM ribosomal protein FOC86_24160 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC86_24170 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC86_24215 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC86_24245 ENOG4105D1F ATP-binding protein FOC86_24260 ENOG4108NMV polysaccharide deacetylase FOC86_24340 ENOG4105C8B TIGR00159 family FOC86_24345 ENOG4107U5W ybbr family FOC86_24370 ENOG4108VQT Alpha beta hydrolase fold protein FOC86_24380 ENOG4105CMG Carbohydrate kinase FOC86_24390 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FOC86_24395 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FOC86_24415 ENOG4108PSK reductase FOC86_24430 ENOG4105IQ5 FAD linked oxidase domain protein FOC86_24445 ENOG4105C2C drug resistance transporter, Bcr CflA FOC86_24460 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC86_24465 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_24470 ENOG4105C3U ABC transporter FOC86_24475 ENOG4108JQ7 (ABC) transporter FOC86_24500 ENOG4105U5Y Transcriptional regulator FOC86_24510 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_24515 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_24525 ENOG4105II7 pyrroline-5-carboxylate reductase FOC86_24530 ENOG4107XDY Nicotinamide Mononucleotide Transporter FOC86_24540 ENOG4105E0C molybdate abc transporter FOC86_24545 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC86_24550 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FOC86_24580 ENOG4105F6E Acyl-transferase FOC86_24600 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC86_24610 ENOG4108RE7 deoxyribonuclease FOC86_24620 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FOC86_24645 ENOG4105C5H ABC transporter FOC86_24660 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC86_24670 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC86_24675 ENOG4105C3U ABC transporter FOC86_24680 ENOG4108JQ7 (ABC) transporter FOC86_24685 ENOG410667J hydrolase FOC86_24715 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FOC86_24720 ENOG4105ERH Fumarylacetoacetate hydrolase FOC86_24730 ENOG4108SC4 )-transporter FOC86_24735 ENOG4105CPF Cell wall formation (By similarity) FOC86_24740 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC86_24755 ENOG4107ZXI Rhomboid family FOC86_24765 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FOC86_24770 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC86_24780 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FOC86_24880 ENOG4105K8N protein family UPF0079, ATPase FOC86_24885 ENOG41072GX Peptidase M22 Glycoprotease FOC86_24890 ENOG410801F ribosomal-protein-alanine acetyltransferase FOC86_24900 ENOG4105C5H ABC transporter FOC86_24915 ENOG4108TYN CAAX amino terminal protease family protein FOC86_24935 ENOG4105C7N Xanthine uracil vitamin C permease FOC86_24945 ENOG4105BZU Histidine kinase FOC86_24970 ENOG4107ZXU DSBA oxidoreductase FOC86_25040 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC86_25060 ENOG4105SX7 Transporter FOC86_25085 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOC86_25090 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOC86_25095 ENOG4105C83 adenylosuccinate lyase FOC86_25105 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FOC86_25130 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOC86_25140 ENOG4105C12 Phosphoribosylglycinamide synthetase FOC86_25165 ENOG4105C4R Atp-dependent dna helicase FOC86_25195 ENOG4108W2Y isochorismatase FOC86_25205 ENOG4108UMI ABC transporter, permease FOC86_25210 ENOG4105D01 (LipO)protein FOC86_25230 ENOG410834F Transcriptional regulator FOC86_25235 ENOG4107I77 yiaA/B two helix domain FOC86_25255 ENOG4105CBD Diacylglycerol kinase FOC86_25260 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FOC86_25265 ENOG4108JPW Aminotransferase FOC86_25275 ENOG4105C26 Dehydrogenase FOC86_25280 ENOG4105KPY Small multidrug resistance protein FOC86_25300 ENOG4105D9N nucleoside FOC86_25305 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC86_25315 ENOG4105BZU Histidine kinase FOC86_25320 ENOG4108W15 Protein of unknown function (DUF1456) FOC86_25340 ENOG4105DTQ mandelate racemase muconate lactonizing FOC86_25350 ENOG4105DFD Na H antiporter FOC86_25370 ENOG4105D3R alkyl hydroperoxide reductase FOC86_25390 ENOG4105EHG Permease protein FOC86_25395 ENOG4105DQ5 transport system permease protein FOC86_25400 ENOG4108V5C ABC transporter FOC86_25420 ENOG4106UIA FOC86_25425 ENOG4106UIA FOC86_25460 ENOG410756H nucleotidyltransferase FOC86_25480 ENOG4105E5Q amino acid AbC transporter FOC86_25485 ENOG4105EAB amino acid AbC transporter FOC86_25495 ENOG4105C8Q Methyl-accepting chemotaxis FOC86_25500 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_25525 ENOG4105C5B carbamate kinase FOC86_25545 ENOG4105CI1 PTS System FOC86_25575 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOC86_25590 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC86_25610 ENOG4105C5H ABC transporter FOC86_25640 ENOG41062JF Transcriptional regulator FOC86_25660 ENOG4105DEU major facilitator superfamily FOC86_25690 ENOG4108N0M stress protein FOC86_25695 ENOG4106FN3 tellurium resistance protein FOC86_25700 ENOG4106FN3 tellurium resistance protein FOC86_25705 ENOG4107TS3 membrane protein, TerC FOC86_25710 ENOG4108TTB tellurium resistance protein FOC86_25730 ENOG4105KJF protein tyrosine phosphatase FOC86_25740 ENOG4107U9T Pfam:Ribonuclease_BN FOC86_25745 ENOG4105C59 p-type ATPase FOC86_25750 ENOG4108IPJ Membrane FOC86_25775 ENOG4107ZTW SNARE associated Golgi FOC86_25790 ENOG410606W general stress protein FOC86_25795 ENOG4105UPD Calcium Proton FOC86_25830 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC86_25845 ENOG4108JUB Transcriptional regulator FOC86_25855 ENOG4108IQI permease FOC86_25895 ENOG4108A04 Beta-lactamase FOC86_25915 ENOG4105CKK Glycosyl transferase, family 2 FOC86_25920 ENOG4107QQG Dehydrogenase FOC86_25925 ENOG4105C3I Nad-dependent epimerase dehydratase FOC86_25945 ENOG4105F1A Pyruvate formate-lyase FOC86_25965 ENOG4105CI2 imidazolone-5-propionate hydrolase FOC86_25970 ENOG4105ECP epimerase FOC86_26000 ENOG41067AE Membrane-bound metal-dependent hydrolase FOC86_26005 ENOG4105CEN a g-specific adenine glycosylase FOC86_26010 ENOG4106BXE FOC86_26030 ENOG4105BZ1 (ABC) transporter FOC86_26035 ENOG4107NBY Membrane FOC86_26040 ENOG4105CBC glutamate synthase FOC86_26050 ENOG4108IUW ABC transporter FOC86_26070 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC86_26075 ENOG4105G5W regulator Fur family FOC86_26190 ENOG4108JQC penicillin-binding protein 1A FOC86_26195 ENOG4107ZQN disulfide bond FOC86_26205 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOC86_26215 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOC86_26220 ENOG4105BZU Histidine kinase FOC86_26225 ENOG4105CYN Serine protein kinase FOC86_26240 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC86_26245 ENOG4105C94 Transporter FOC86_26260 ENOG4105DZ6 Band 7 protein FOC86_26270 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOC86_26275 ENOG4108V9W transcriptional regulatory protein FOC86_26280 ENOG4105D4T Citrate transporter FOC86_26300 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC86_26305 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC86_26310 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FOC86_26315 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FOC86_26320 ENOG4105BZ7 extracellular solute-binding protein family 1 FOC86_26325 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FOC86_26330 ENOG4108STX response regulator FOC86_26335 ENOG4105US7 Histidine kinase FOC86_26360 ENOG4108MRH transcriptional regulatory protein FOC86_26370 ENOG4105C6K Malic enzyme FOC86_26380 ENOG4108UZ3 Transporter FOC86_26385 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC86_26395 ENOG4105BZU Histidine kinase FOC86_26400 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_26405 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC86_26410 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC86_26415 ENOG4108JB9 formate dehydrogenase FOC86_26435 ENOG4105CUB amino acid FOC86_26445 ENOG4105C59 p-type ATPase FOC86_26450 ENOG4105DAP Nicotinate phosphoribosyltransferase FOC86_26485 ENOG41073R8 VanW family FOC86_26500 ENOG4108KGH TRANSCRIPTIONal FOC86_26505 ENOG4105D9N nucleoside FOC86_26510 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOC86_26515 ENOG4105C37 (CBS) domain FOC86_26520 ENOG4108IJ0 Aspartate ammonia-lyase FOC86_26525 ENOG4105DAA L-lactate FOC86_26540 ENOG4105DUX Transporter FOC86_26545 ENOG4108MES Periplasmic binding protein FOC86_26550 ENOG4105DQ5 transport system permease protein FOC86_26555 ENOG4108IHU transport system permease protein FOC86_26560 ENOG4105E0A ABC, transporter FOC86_26565 ENOG4105DMQ Methyltransferase FOC86_26575 ENOG4105EXW epimerase dehydratase FOC86_26580 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FOC86_26590 ENOG4107T89 von Willebrand factor, type A FOC86_26595 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FOC86_26600 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC86_26615 ENOG4105BZU Histidine kinase FOC86_26620 ENOG4105D5Q Arginine ornithine antiporter FOC86_26625 ENOG4107414 GntR family transcriptional regulator FOC86_26630 ENOG4105C5Y PTS System FOC86_26635 ENOG4105CG3 alpha amylase, catalytic region FOC86_26650 ENOG4105E1K spore germination protein FOC86_26660 ENOG4105CRN Aminoglycoside phosphotransferase FOC86_26665 ENOG4105BZG amino acid carrier protein FOC86_26670 ENOG4105CDA abc transporter atp-binding protein FOC86_26675 ENOG4105CT1 (ABC) transporter FOC86_26680 ENOG4105EAD ABC transporter FOC86_26685 ENOG4105DRP amino acid AbC transporter FOC86_26690 ENOG4108IQI permease FOC86_26715 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC86_26720 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC86_26725 ENOG4105BZU Histidine kinase FOC86_26730 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC86_26740 ENOG4105CHH sulfate transporter FOC86_26745 ENOG41068KF Universal stress protein FOC86_26755 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC86_26765 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC86_26770 ENOG4108JQ7 (ABC) transporter FOC86_26780 ENOG4105CXY transporter FOC86_26785 ENOG41067TZ transcriptional regulator, MarR family FOC86_26790 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC86_26795 ENOG4105ETE Transcriptional regulator (LacI family FOC86_26800 ENOG4108RVA ribokinase FOC86_26815 ENOG4105CNN ABC, transporter FOC86_26820 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOC86_26890 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC86_26895 ENOG41069ER domain protein FOC86_26900 ENOG4105VZ8 Transcriptional regulator FOC86_26915 ENOG4105DUX Transporter FOC86_26935 ENOG4105C85 amino acid FOC86_26940 ENOG4105C7N Xanthine uracil vitamin C permease FOC86_26955 ENOG4105MA6 gCN5-related N-acetyltransferase FOC86_26980 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOC86_26985 ENOG4105E2S oxidase) subunit II FOC86_26990 ENOG4108IQI permease FOC86_27005 ENOG4106CAD Protein of unknown function (DUF3311) FOC86_27010 ENOG4105E1V na solute symporter FOC86_27025 ENOG4108NHD germination protein FOC86_27030 ENOG4105CE1 Ferrous iron transport protein b FOC86_27035 ENOG4105CE1 Ferrous iron transport protein b FOC86_27040 ENOG4105CE1 Ferrous iron transport protein b FOC86_27045 ENOG4105CVA phosphate FOC86_27050 ENOG4105C8U phosphate abc transporter FOC86_27055 ENOG4105E2Z phosphate ABC transporter (Permease FOC86_27185 ENOG41080XQ Signal transduction protein with cbs domains FOC86_27205 ENOG4105ETU transcriptional activator (TenA FOC86_27215 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC86_27225 ENOG4108VEU Thiamine monophosphate synthase FOC86_27230 ENOG41080HI glycine oxidase FOC86_27245 ENOG4105D06 uba thif-type nad fad binding protein FOC86_27250 ENOG4105DWF phosphomethylpyrimidine kinase FOC86_27300 ENOG4108INS Transcriptional regulator FOC86_27325 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC86_27335 ENOG4105CNN ABC, transporter FOC86_27340 ENOG4105C2J ABC transporter FOC86_27350 ENOG4105C7N Xanthine uracil vitamin C permease FOC86_27360 ENOG4108PXI ErfK YbiS YcfS YnhG FOC86_27380 ENOG4105C5Y PTS System FOC86_27415 ENOG4108B31 Spore germination protein FOC86_27435 ENOG4107Y03 Nitroreductase FOC86_27440 ENOG4105ED1 spovr family FOC86_27460 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FOC86_27465 ENOG4105XTG Pfam:DUF156 FOC86_27470 ENOG4105VFE sira family FOC86_27475 ENOG4107TPS domain protein FOC86_27480 ENOG4105VFE sira family FOC86_27485 ENOG41085GJ domain protein FOC86_27495 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FOC86_27500 ENOG41087NI Sulfite exporter TauE/SafE FOC86_27510 ENOG4108KGH TRANSCRIPTIONal FOC86_27515 ENOG4105CZN Potassium uptake protein FOC86_27535 ENOG4105EMD TRANSCRIPTIONal FOC86_27540 ENOG4105VCP PTS System FOC86_27545 ENOG4105VZJ PTS System FOC86_27565 ENOG41069ER domain protein