locus-tag	class	description
K8Z38_00005	COG3728	DNA packaging
K8Z38_00005	COG5484	DNA packaging
K8Z38_00095	COG4824	toxin secretion phage lysis holin
K8Z38_00115	COG2252	PERMEase
K8Z38_00125	COG5002	protein histidine kinase activity
K8Z38_00150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z38_00190	COG2205	protein histidine kinase activity
K8Z38_00195	COG0745	RESPONSE REGULATOR receiver
K8Z38_00235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z38_00245	COG1216	Glycosyl transferase, family 2
K8Z38_00245	COG0463	Glycosyl transferase, family 2
K8Z38_00265	COG0697	spore germination
K8Z38_00295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z38_00300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z38_00305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z38_00315	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z38_00330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z38_00340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z38_00350	COG0151	Belongs to the GarS family
K8Z38_00375	COG0210	DNA helicase
K8Z38_00385	COG4851	CamS sex pheromone cAM373 precursor
K8Z38_00400	COG1335	isochorismatase
K8Z38_00410	COG2011	ABC-type metal ion transport system permease component
K8Z38_00415	COG1464	Belongs to the NlpA lipoprotein family
K8Z38_00430	COG0003	Pfam Anion-transporting ATPase
K8Z38_00435	COG1846	Transcriptional regulator
K8Z38_00440	COG4682	membrane
K8Z38_00460	COG1597	lipid kinase activity
K8Z38_00470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z38_00480	COG1012	belongs to the aldehyde dehydrogenase family
K8Z38_00485	COG2076	Multidrug Resistance protein
K8Z38_00495	COG2309	aminopeptidase activity
K8Z38_00515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z38_00525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z38_00530	COG4807	Protein conserved in bacteria
K8Z38_00560	COG1473	amidohydrolase
K8Z38_00575	COG0450	alkyl hydroperoxide reductase
K8Z38_00595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_00600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_00605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z38_00610	COG0492	ferredoxin-NADP+ reductase activity
K8Z38_00620	COG0166	Belongs to the GPI family
K8Z38_00645	COG5002	protein histidine kinase activity
K8Z38_00665	COG3541	Predicted nucleotidyltransferase
K8Z38_00670	COG2814	Major facilitator Superfamily
K8Z38_00675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z38_00675	COG0723	plastoquinol--plastocyanin reductase activity
K8Z38_00685	COG0765	amino acid transport
K8Z38_00690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z38_00700	COG0840	transmembrane signaling receptor activity
K8Z38_00725	COG0549	Belongs to the carbamate kinase family
K8Z38_00730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z38_00745	COG0366	Alpha amylase catalytic
K8Z38_00750	COG2190	(PTS) system
K8Z38_00750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z38_00750	COG1263	PTS System
K8Z38_00780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z38_00800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z38_00810	COG1116	anion transmembrane transporter activity
K8Z38_00860	COG2270	Major facilitator Superfamily
K8Z38_00890	COG2310	stress, protein
K8Z38_00895	COG2310	stress, protein
K8Z38_00900	COG2310	stress, protein
K8Z38_00905	COG0861	Integral membrane protein TerC family
K8Z38_00915	COG3853	Toxic anion resistance protein (TelA)
K8Z38_00930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z38_00940	COG1295	ribonuclease BN
K8Z38_00945	COG2217	Heavy metal translocating P-type atpase
K8Z38_00950	COG0697	spore germination
K8Z38_00970	COG0586	Pfam SNARE associated Golgi protein
K8Z38_00985	COG3871	stress protein (general stress protein 26)
K8Z38_00990	COG0387	Pfam Sodium calcium exchanger
K8Z38_01000	COG0535	radical SAM domain protein
K8Z38_01020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z38_01025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z38_01040	COG3829	transcription factor binding
K8Z38_01050	COG0833	amino acid
K8Z38_01055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z38_01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z38_01085	COG1263	PTS System
K8Z38_01090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z38_01105	COG0463	Glycosyl transferase, family 2
K8Z38_01115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z38_01115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z38_01135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z38_01155	COG1228	amidohydrolase
K8Z38_01160	COG1090	epimerase
K8Z38_01190	COG1988	membrane-bound metal-dependent
K8Z38_01195	COG1194	a g-specific adenine glycosylase
K8Z38_01220	COG1132	(ABC) transporter
K8Z38_01225	COG4129	membrane
K8Z38_01230	COG0070	glutamate synthase
K8Z38_01230	COG0069	glutamate synthase activity
K8Z38_01230	COG0067	glutamate synthase
K8Z38_01245	COG4555	ABC transporter
K8Z38_01265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z38_01270	COG0735	belongs to the Fur family
K8Z38_01375	COG4974	Belongs to the 'phage' integrase family
K8Z38_01400	COG0582	viral genome integration into host DNA
K8Z38_01465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z38_01500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z38_01505	COG5001	Diguanylate cyclase
K8Z38_01505	COG1716	ATPase activity
K8Z38_01510	COG2766	serine protein kinase
K8Z38_01530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z38_01540	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z38_01545	COG2268	Band 7 protein
K8Z38_01555	COG3290	protein histidine kinase activity
K8Z38_01560	COG4565	transcriptional regulatory protein
K8Z38_01565	COG2851	Citrate transporter
K8Z38_01590	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z38_01595	COG3842	ATPase activity
K8Z38_01600	COG1175	transmembrane transport
K8Z38_01605	COG0395	ABC-type sugar transport system, permease component
K8Z38_01615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z38_01620	COG0745	RESPONSE REGULATOR receiver
K8Z38_01625	COG3850	Histidine kinase
K8Z38_01625	COG5002	protein histidine kinase activity
K8Z38_01635	COG4990	cell redox homeostasis
K8Z38_01645	COG3290	protein histidine kinase activity
K8Z38_01650	COG4565	transcriptional regulatory protein
K8Z38_01655	COG3493	citrate carrier protein
K8Z38_01660	COG0281	malic enzyme
K8Z38_01670	COG0697	spore germination
K8Z38_01675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_01685	COG5002	protein histidine kinase activity
K8Z38_01690	COG0745	RESPONSE REGULATOR receiver
K8Z38_01700	COG0454	-acetyltransferase
K8Z38_01700	COG0456	acetyltransferase
K8Z38_01705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z38_01710	COG3383	formate dehydrogenase (NAD+) activity
K8Z38_01715	COG2427	Protein of unknown function (DUF1641)
K8Z38_01740	COG0640	Transcriptional regulator
K8Z38_01745	COG2217	Heavy metal translocating P-type atpase
K8Z38_01750	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z38_01765	COG3227	Zinc metalloprotease (Elastase)
K8Z38_01785	COG2720	vancomycin resistance protein
K8Z38_01790	COG1316	TRANSCRIPTIONal
K8Z38_01795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z38_01800	COG0346	lactoylglutathione lyase activity
K8Z38_01805	COG1253	flavin adenine dinucleotide binding
K8Z38_01810	COG1027	Aspartate ammonia-lyase
K8Z38_01815	COG1620	l-lactate permease
K8Z38_01830	COG3104	oligopeptide transport
K8Z38_01835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z38_01840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_01845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_01855	COG2226	methyltransferase
K8Z38_01865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z38_01875	COG4548	von Willebrand factor, type A
K8Z38_01880	COG0714	Associated with various cellular activities
K8Z38_01900	COG0531	amino acid
K8Z38_01905	COG2188	Transcriptional regulator
K8Z38_01910	COG1263	PTS System
K8Z38_01910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z38_01915	COG0366	Alpha amylase catalytic
K8Z38_01930	COG0697	spore germination
K8Z38_01935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z38_01940	COG1115	amino acid carrier protein
K8Z38_01945	COG1126	abc transporter atp-binding protein
K8Z38_01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z38_01955	COG0765	amino acid transport
K8Z38_01960	COG0765	amino acid transport
K8Z38_01965	COG0833	amino acid
K8Z38_01980	COG1595	DNA-templated transcription, initiation
K8Z38_01990	COG2378	regulation of single-species biofilm formation
K8Z38_01995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z38_02000	COG5002	protein histidine kinase activity
K8Z38_02045	COG1846	Transcriptional regulator
K8Z38_02050	COG0477	Major facilitator Superfamily
K8Z38_02055	COG1609	Transcriptional regulator
K8Z38_02060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z38_02075	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z38_02080	COG1879	ABC-type sugar transport system periplasmic component
K8Z38_02110	COG1063	alcohol dehydrogenase
K8Z38_02145	COG1396	sequence-specific DNA binding
K8Z38_02235	COG3331	DNA recombination
K8Z38_02295	COG3728	DNA packaging
K8Z38_02295	COG5484	DNA packaging
K8Z38_02420	COG1674	ftsk spoiiie
K8Z38_02465	COG0840	transmembrane signaling receptor activity
K8Z38_02470	COG3584	3D domain protein
K8Z38_02470	COG3583	domain protein
K8Z38_02475	COG1476	TRANSCRIPTIONal
K8Z38_02495	COG3104	oligopeptide transport
K8Z38_02500	COG1114	Component of the transport system for branched-chain amino acids
K8Z38_02515	COG1113	amino acid transport
K8Z38_02520	COG2252	PERMEase
K8Z38_02535	COG2153	protein acetylation
K8Z38_02545	COG0475	glutathione-regulated potassium exporter activity
K8Z38_02545	COG0569	domain protein
K8Z38_02555	COG1845	cytochrome c oxidase, subunit III
K8Z38_02560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z38_02570	COG0833	amino acid
K8Z38_02575	COG4990	cell redox homeostasis
K8Z38_02590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z38_02595	COG0697	spore germination
K8Z38_02600	COG0531	amino acid
K8Z38_02615	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z38_02620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z38_02625	COG1918	ferrous iron import across plasma membrane
K8Z38_02625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z38_02630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z38_02635	COG0573	inorganic phosphate transmembrane transporter activity
K8Z38_02640	COG0581	inorganic phosphate transmembrane transporter activity
K8Z38_02645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z38_02765	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z38_02785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z38_02790	COG1116	anion transmembrane transporter activity
K8Z38_02795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z38_02800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z38_02805	COG0352	thiamine-phosphate diphosphorylase activity
K8Z38_02810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z38_02815	COG2104	thiamine diphosphate biosynthetic process
K8Z38_02825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z38_02830	COG0351	phosphomethylpyrimidine kinase
K8Z38_02870	COG2205	protein histidine kinase activity
K8Z38_02875	COG2814	Major facilitator Superfamily
K8Z38_02880	COG1846	Transcriptional regulator
K8Z38_02905	COG1136	(ABC) transporter
K8Z38_02915	COG2252	PERMEase
K8Z38_02920	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_02980	COG0778	Nitroreductase
K8Z38_02985	COG2719	SpoVR family
K8Z38_02995	COG3591	Belongs to the peptidase S1B family
K8Z38_03005	COG0446	pyridine nucleotide-disulphide oxidoreductase
K8Z38_03010	COG1937	Protein conserved in bacteria
K8Z38_03015	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z38_03015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z38_03020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z38_03020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_03025	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z38_03040	COG2210	Belongs to the sulfur carrier protein TusA family
K8Z38_03045	COG0730	response to heat
K8Z38_03055	COG1316	TRANSCRIPTIONal
K8Z38_03060	COG0604	alcohol dehydrogenase
K8Z38_03065	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8Z38_03080	COG3711	transcriptional antiterminator
K8Z38_03080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z38_03085	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z38_03090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z38_03115	COG3584	3D domain protein
K8Z38_03115	COG1388	LysM domain
K8Z38_03120	COG0577	efflux transmembrane transporter activity
K8Z38_03125	COG1136	(ABC) transporter
K8Z38_03135	COG5522	Integral membrane protein (intg_mem_TP0381)
K8Z38_03150	COG1114	Component of the transport system for branched-chain amino acids
K8Z38_03155	COG3546	catalase activity
K8Z38_03190	COG0586	Pfam SNARE associated Golgi protein
K8Z38_03225	COG0531	amino acid
K8Z38_03230	COG0475	glutathione-regulated potassium exporter activity
K8Z38_03240	COG1737	Transcriptional regulator
K8Z38_03250	COG1263	PTS System
K8Z38_03250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z38_03260	COG2259	Doxx family
K8Z38_03280	COG1522	sequence-specific DNA binding
K8Z38_03285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K8Z38_03285	COG0165	Argininosuccinate lyase
K8Z38_03290	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_03310	COG1309	transcriptional regulator
K8Z38_03315	COG2814	Major facilitator Superfamily
K8Z38_03320	COG1733	regulation of RNA biosynthetic process
K8Z38_03335	COG4533	DNA binding
K8Z38_03340	COG2211	Major facilitator Superfamily
K8Z38_03355	COG0693	protein deglycase activity
K8Z38_03360	COG0753	catalase activity
K8Z38_03370	COG0531	amino acid
K8Z38_03385	COG1012	belongs to the aldehyde dehydrogenase family
K8Z38_03390	COG1132	(ABC) transporter
K8Z38_03395	COG1132	(ABC) transporter
K8Z38_03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z38_03405	COG0765	amino acid transport
K8Z38_03410	COG1126	abc transporter atp-binding protein
K8Z38_03425	COG0189	ligase activity
K8Z38_03455	COG0028	Belongs to the TPP enzyme family
K8Z38_03460	COG3527	Alpha-acetolactate decarboxylase
K8Z38_03475	COG0561	phosphatase activity
K8Z38_03485	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_03485	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_03490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z38_03495	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_03510	COG0659	secondary active sulfate transmembrane transporter activity
K8Z38_03515	COG2244	polysaccharide biosynthetic process
K8Z38_03535	COG1024	Enoyl-CoA hydratase
K8Z38_03555	COG1363	Peptidase, m42
K8Z38_03595	COG0601	transmembrane transport
K8Z38_03600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z38_03605	COG0444	Belongs to the ABC transporter superfamily
K8Z38_03610	COG4608	Belongs to the ABC transporter superfamily
K8Z38_03615	COG0322	excinuclease ABC activity
K8Z38_03630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_03730	COG0477	Major facilitator Superfamily
K8Z38_03735	COG3290	protein histidine kinase activity
K8Z38_03740	COG4565	transcriptional regulatory protein
K8Z38_03745	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z38_03750	COG0494	nUDIX hydrolase
K8Z38_03765	COG0305	Participates in initiation and elongation during chromosome replication
K8Z38_03785	COG0305	Participates in initiation and elongation during chromosome replication
K8Z38_03810	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K8Z38_03815	COG1288	antiporter activity
K8Z38_03825	COG1842	Phage shock protein A
K8Z38_03835	COG0477	Major facilitator Superfamily
K8Z38_03855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_03910	COG2020	methyltransferase activity
K8Z38_03940	COG1073	alpha beta
K8Z38_03950	COG2801	Transposase and inactivated derivatives
K8Z38_03980	COG0577	efflux transmembrane transporter activity
K8Z38_03995	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z38_04000	COG1522	sequence-specific DNA binding
K8Z38_04015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z38_04070	COG1183	phosphatidylcholine synthase activity
K8Z38_04085	COG2814	Major facilitator Superfamily
K8Z38_04090	COG0640	Transcriptional regulator
K8Z38_04115	COG2376	Dihydroxyacetone kinase
K8Z38_04125	COG2376	Dihydroxyacetone kinase
K8Z38_04155	COG2373	Large extracellular alpha-helical protein
K8Z38_04235	COG1191	sigma factor activity
K8Z38_04245	COG2208	phosphoserine phosphatase activity
K8Z38_04250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z38_04255	COG5002	protein histidine kinase activity
K8Z38_04255	COG0784	Response regulator, receiver
K8Z38_04255	COG2205	protein histidine kinase activity
K8Z38_04295	COG2807	transmembrane transport
K8Z38_04300	COG2186	Transcriptional regulator
K8Z38_04310	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z38_04330	COG0420	3'-5' exonuclease activity
K8Z38_04335	COG4717	serine-type aminopeptidase activity
K8Z38_04345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z38_04360	COG0346	lactoylglutathione lyase activity
K8Z38_04365	COG0346	lactoylglutathione lyase activity
K8Z38_04370	COG0457	Tetratricopeptide repeat
K8Z38_04380	COG2267	carboxylic ester hydrolase activity
K8Z38_04400	COG2140	Oxalate decarboxylase
K8Z38_04405	COG3620	sequence-specific DNA binding
K8Z38_04410	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z38_04415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z38_04425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z38_04440	COG1595	DNA-templated transcription, initiation
K8Z38_04450	COG0772	Belongs to the SEDS family
K8Z38_04455	COG3973	AAA domain
K8Z38_04480	COG4980	gas vesicle protein
K8Z38_04485	COG0537	adenosine 5'-monophosphoramidase activity
K8Z38_04490	COG1131	(ABC) transporter
K8Z38_04495	COG4473	ABC transporter
K8Z38_04510	COG1309	transcriptional regulator
K8Z38_04520	COG3402	PFAM membrane-flanked domain
K8Z38_04525	COG3428	Bacterial PH domain
K8Z38_04560	COG0697	spore germination
K8Z38_04565	COG3402	PFAM membrane-flanked domain
K8Z38_04570	COG3428	Bacterial PH domain
K8Z38_04575	COG2329	Antibiotic biosynthesis monooxygenase
K8Z38_04580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z38_04595	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z38_04630	COG1484	DNA-dependent DNA replication
K8Z38_04645	COG1309	transcriptional regulator
K8Z38_04680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_04685	COG1609	Transcriptional regulator
K8Z38_04695	COG1234	tRNA 3'-trailer cleavage
K8Z38_04700	COG0095	Lipoate-protein ligase
K8Z38_04710	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_04720	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K8Z38_04730	COG4208	sulfate ABC transporter
K8Z38_04825	COG1073	alpha beta
K8Z38_04830	COG1408	metallophosphoesterase
K8Z38_04835	COG1078	dGTPase activity
K8Z38_04845	COG1595	DNA-templated transcription, initiation
K8Z38_04850	COG2207	Transcriptional regulator
K8Z38_04850	COG3708	Transcriptional regulator
K8Z38_04860	COG2205	protein histidine kinase activity
K8Z38_04865	COG0745	RESPONSE REGULATOR receiver
K8Z38_04885	COG0501	Belongs to the peptidase M48B family
K8Z38_04890	COG0840	transmembrane signaling receptor activity
K8Z38_04895	COG3693	PFAM glycoside hydrolase, family 10
K8Z38_04905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z38_04910	COG2224	Isocitrate lyase
K8Z38_04925	COG1278	Cold shock
K8Z38_04945	COG0398	Pfam SNARE associated Golgi protein
K8Z38_05005	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z38_05030	COG0367	asparagine synthase
K8Z38_05040	COG0753	catalase activity
K8Z38_05050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z38_05075	COG3339	Conserved Protein
K8Z38_05080	COG0004	ammonium transporteR
K8Z38_05100	COG2996	Protein conserved in bacteria
K8Z38_05125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_05140	COG0561	phosphatase activity
K8Z38_05160	COG2267	carboxylic ester hydrolase activity
K8Z38_05175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z38_05180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z38_05185	COG5504	Zn-dependent protease
K8Z38_05195	COG0180	Tryptophanyl-tRNA synthetase
K8Z38_05205	COG4166	transmembrane transport
K8Z38_05210	COG0601	transmembrane transport
K8Z38_05215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z38_05220	COG0444	Belongs to the ABC transporter superfamily
K8Z38_05225	COG4608	Belongs to the ABC transporter superfamily
K8Z38_05230	COG0534	Mate efflux family protein
K8Z38_05235	COG4166	transmembrane transport
K8Z38_05250	COG0861	Integral membrane protein TerC family
K8Z38_05260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z38_05270	COG1164	Oligoendopeptidase f
K8Z38_05285	COG2346	COG2346, Truncated hemoglobins
K8Z38_05290	COG4116	CYTH
K8Z38_05300	COG2357	RelA SpoT domain protein
K8Z38_05310	COG0564	pseudouridine synthase activity
K8Z38_05325	COG0772	Belongs to the SEDS family
K8Z38_05330	COG1216	Glycosyl transferase, family 2
K8Z38_05350	COG0457	Tetratricopeptide repeat
K8Z38_05350	COG0463	Glycosyl transferase, family 2
K8Z38_05370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z38_05385	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z38_05430	COG2153	protein acetylation
K8Z38_05440	COG2382	esterase
K8Z38_05465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z38_05475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z38_05475	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z38_05510	COG1620	l-lactate permease
K8Z38_05515	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z38_05555	COG2226	methyltransferase
K8Z38_05575	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z38_05585	COG1476	TRANSCRIPTIONal
K8Z38_05625	COG4152	abc transporter atp-binding protein
K8Z38_05630	COG1668	transmembrane transport
K8Z38_05650	COG2226	methyltransferase
K8Z38_05660	COG1686	Belongs to the peptidase S11 family
K8Z38_05665	COG0681	Belongs to the peptidase S26 family
K8Z38_05700	COG1012	belongs to the aldehyde dehydrogenase family
K8Z38_05710	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z38_05715	COG1177	transmembrane transport
K8Z38_05730	COG2409	Drug exporters of the RND superfamily
K8Z38_05740	COG0564	pseudouridine synthase activity
K8Z38_05750	COG2340	Cysteine-rich secretory protein family
K8Z38_05755	COG0247	lactate metabolic process
K8Z38_05760	COG0277	FAD linked oxidase domain protein
K8Z38_05765	COG3835	regulator
K8Z38_05775	COG0745	RESPONSE REGULATOR receiver
K8Z38_05780	COG5002	protein histidine kinase activity
K8Z38_05785	COG2186	Transcriptional regulator
K8Z38_05805	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z38_05815	COG2116	formate transmembrane transporter activity
K8Z38_05820	COG0861	Integral membrane protein TerC family
K8Z38_05825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z38_05835	COG2030	dehydratase
K8Z38_05855	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_05860	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z38_05870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z38_05885	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z38_05890	COG3842	ATPase activity
K8Z38_05915	COG1349	DNA-binding transcription factor activity
K8Z38_05930	COG0235	Class ii aldolase
K8Z38_05940	COG2861	carbohydrate metabolic process
K8Z38_05950	COG3852	Histidine kinase
K8Z38_05955	COG1846	Transcriptional regulator
K8Z38_05965	COG2318	DinB family
K8Z38_05975	COG5002	protein histidine kinase activity
K8Z38_05985	COG0720	synthase
K8Z38_06000	COG4873	Protein conserved in bacteria
K8Z38_06030	COG1780	Probably involved in ribonucleotide reductase function
K8Z38_06035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z38_06045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z38_06050	COG1725	Transcriptional regulator
K8Z38_06055	COG1131	(ABC) transporter
K8Z38_06065	COG1131	(ABC) transporter
K8Z38_06085	COG1522	sequence-specific DNA binding
K8Z38_06095	COG1335	isochorismatase
K8Z38_06105	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z38_06110	COG2070	2-Nitropropane dioxygenase
K8Z38_06115	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z38_06125	COG1696	Membrane protein involved in D-alanine export
K8Z38_06150	COG0716	FMN binding
K8Z38_06200	COG1846	Transcriptional regulator
K8Z38_06210	COG1301	dicarboxylic acid transport
K8Z38_06215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z38_06220	COG4709	membrane
K8Z38_06225	COG3874	Sporulation protein YtfJ
K8Z38_06245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z38_06250	COG0028	Belongs to the TPP enzyme family
K8Z38_06255	COG0440	acetolactate synthase activity
K8Z38_06330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z38_06345	COG1183	phosphatidylcholine synthase activity
K8Z38_06350	COG1368	sulfuric ester hydrolase activity
K8Z38_06360	COG0019	diaminopimelate decarboxylase activity
K8Z38_06380	COG0529	Catalyzes the synthesis of activated sulfate
K8Z38_06385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z38_06405	COG1648	precorrin-2 dehydrogenase activity
K8Z38_06410	COG0733	neurotransmitter:sodium symporter activity
K8Z38_06435	COG1757	Na H antiporter
K8Z38_06450	COG4758	membrane
K8Z38_06455	COG4585	Histidine kinase
K8Z38_06460	COG2197	response regulator
K8Z38_06470	COG1114	Component of the transport system for branched-chain amino acids
K8Z38_06520	COG0730	response to heat
K8Z38_06525	COG0306	phosphate transporter
K8Z38_06530	COG1392	Phosphate transport regulator
K8Z38_06535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z38_06550	COG3852	Histidine kinase
K8Z38_06555	COG1801	Protein of unknown function DUF72
K8Z38_06565	COG0582	viral genome integration into host DNA
K8Z38_06570	COG5002	protein histidine kinase activity
K8Z38_06585	COG0392	lysyltransferase activity
K8Z38_06585	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z38_06600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z38_06605	COG1686	Belongs to the peptidase S11 family
K8Z38_06610	COG2715	membrane protein required for spore maturation
K8Z38_06615	COG0700	Nucleoside recognition
K8Z38_06620	COG1187	pseudouridine synthase activity
K8Z38_06630	COG1333	cytochrome c biogenesis protein
K8Z38_06635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z38_06640	COG0745	RESPONSE REGULATOR receiver
K8Z38_06645	COG5002	protein histidine kinase activity
K8Z38_06650	COG2096	Adenosyltransferase
K8Z38_06665	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z38_06670	COG1141	Ferredoxin
K8Z38_06680	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z38_06685	COG1266	CAAX protease self-immunity
K8Z38_06695	COG1408	metallophosphoesterase
K8Z38_06700	COG0789	Transcriptional regulator
K8Z38_06710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z38_06730	COG0492	ferredoxin-NADP+ reductase activity
K8Z38_06735	COG0252	asparaginase activity
K8Z38_06805	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z38_06820	COG0142	geranyltranstransferase activity
K8Z38_06830	COG0142	geranyltranstransferase activity
K8Z38_06860	COG0457	Tetratricopeptide repeat
K8Z38_06880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z38_06885	COG2010	Cytochrome c
K8Z38_06885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z38_06890	COG4347	Protein of unknown function (DUF1405)
K8Z38_06905	COG2738	Putative neutral zinc metallopeptidase
K8Z38_06915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_06920	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z38_06940	COG0438	transferase activity, transferring glycosyl groups
K8Z38_06975	COG1199	ATP-dependent helicase activity
K8Z38_06975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z38_06995	COG3935	DnaD domain protein
K8Z38_07000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z38_07010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z38_07010	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z38_07065	COG0116	Belongs to the methyltransferase superfamily
K8Z38_07075	COG1199	ATP-dependent helicase activity
K8Z38_07080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z38_07090	COG0024	Methionine aminopeptidase
K8Z38_07100	COG2233	PERMEase
K8Z38_07105	COG2311	Membrane
K8Z38_07110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z38_07120	COG0456	acetyltransferase
K8Z38_07150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z38_07165	COG3944	biosynthesis protein
K8Z38_07175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z38_07190	COG1215	transferase activity, transferring glycosyl groups
K8Z38_07195	COG0438	transferase activity, transferring glycosyl groups
K8Z38_07210	COG0454	-acetyltransferase
K8Z38_07230	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z38_07265	COG3403	YqcI/YcgG family
K8Z38_07270	COG1280	lysine exporter protein (LysE YggA)
K8Z38_07290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z38_07295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z38_07305	COG0475	glutathione-regulated potassium exporter activity
K8Z38_07310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z38_07315	COG0789	Transcriptional regulator
K8Z38_07315	COG4978	Transcriptional regulator
K8Z38_07325	COG2323	membrane
K8Z38_07330	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z38_07370	COG1923	regulation of RNA biosynthetic process
K8Z38_07380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z38_07385	COG1360	Flagellar Motor Protein
K8Z38_07390	COG2201	protein-glutamate methylesterase activity
K8Z38_07395	COG2198	Histidine kinase
K8Z38_07395	COG0643	Histidine kinase
K8Z38_07400	COG1776	CheC inhibitor of MCP methylation
K8Z38_07400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z38_07415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z38_07435	COG1256	bacterial-type flagellum assembly
K8Z38_07440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z38_07460	COG1815	bacterial-type flagellum-dependent cell motility
K8Z38_07465	COG1558	bacterial-type flagellum-dependent cell motility
K8Z38_07475	COG1766	The M ring may be actively involved in energy transduction
K8Z38_07480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z38_07490	COG1157	protein secretion by the type III secretion system
K8Z38_07525	COG0784	Response regulator, receiver
K8Z38_07525	COG0835	chemotaxis
K8Z38_07540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z38_07545	COG0741	lytic transglycosylase activity
K8Z38_07555	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z38_07560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z38_07560	COG1776	CheC inhibitor of MCP methylation
K8Z38_07570	COG1338	Plays a role in the flagellum-specific transport system
K8Z38_07575	COG1987	bacterial-type flagellum assembly
K8Z38_07585	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z38_07590	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z38_07595	COG1419	protein localization to endoplasmic reticulum
K8Z38_07600	COG4786	Flagellar basal body rod
K8Z38_07605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z38_07640	COG2329	Antibiotic biosynthesis monooxygenase
K8Z38_07665	COG0583	DNA-binding transcription factor activity
K8Z38_07670	COG3842	ATPase activity
K8Z38_07710	COG1686	Belongs to the peptidase S11 family
K8Z38_07715	COG0406	alpha-ribazole phosphatase activity
K8Z38_07730	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z38_07755	COG0367	asparagine synthase
K8Z38_07785	COG1802	Transcriptional regulator
K8Z38_07790	COG0697	spore germination
K8Z38_07800	COG0523	cobalamin synthesis protein
K8Z38_07805	COG0701	Predicted permease
K8Z38_07820	COG1757	Na H antiporter
K8Z38_07825	COG0789	Transcriptional regulator
K8Z38_07855	COG0534	Mate efflux family protein
K8Z38_07860	COG3340	Belongs to the peptidase S51 family
K8Z38_07880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z38_07900	COG2733	membrane
K8Z38_07935	COG1131	(ABC) transporter
K8Z38_07955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z38_07960	COG0528	UMP kinase activity
K8Z38_07970	COG1027	Aspartate ammonia-lyase
K8Z38_07975	COG0281	malic enzyme
K8Z38_07980	COG4191	Histidine kinase
K8Z38_07985	COG0784	Response regulator, receiver
K8Z38_07990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z38_08005	COG3620	sequence-specific DNA binding
K8Z38_08055	COG1695	Transcriptional regulator
K8Z38_08065	COG0477	Major facilitator Superfamily
K8Z38_08075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z38_08080	COG2223	nitrite transmembrane transporter activity
K8Z38_08085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z38_08105	COG0733	neurotransmitter:sodium symporter activity
K8Z38_08110	COG5566	PFAM Mor transcription activator
K8Z38_08115	COG2323	membrane
K8Z38_08135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z38_08145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z38_08150	COG0028	Belongs to the TPP enzyme family
K8Z38_08170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z38_08195	COG2814	Major facilitator Superfamily
K8Z38_08200	COG3384	dioxygenase
K8Z38_08210	COG3279	Response regulator of the LytR AlgR family
K8Z38_08215	COG0427	acetyl-CoA hydrolase
K8Z38_08235	COG4166	transmembrane transport
K8Z38_08240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_08245	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z38_08260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z38_08265	COG0531	amino acid
K8Z38_08300	COG1309	transcriptional regulator
K8Z38_08305	COG2390	Transcriptional regulator
K8Z38_08315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z38_08320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z38_08335	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z38_08345	COG0006	proline dipeptidase activity
K8Z38_08355	COG2132	Multicopper oxidase
K8Z38_08365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z38_08385	COG1114	Component of the transport system for branched-chain amino acids
K8Z38_08400	COG2372	response to copper ion
K8Z38_08400	COG1276	copper resistance
K8Z38_08405	COG4549	nuclear export factor GLE1
K8Z38_08415	COG0697	spore germination
K8Z38_08420	COG0583	DNA-binding transcription factor activity
K8Z38_08425	COG1959	2 iron, 2 sulfur cluster binding
K8Z38_08430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z38_08435	COG0778	Nitroreductase
K8Z38_08445	COG0628	permease
K8Z38_08455	COG1231	oxidoreductase activity
K8Z38_08460	COG0523	cobalamin synthesis protein
K8Z38_08470	COG0411	ABC transporter
K8Z38_08490	COG0583	DNA-binding transcription factor activity
K8Z38_08530	COG1271	oxidase subunit
K8Z38_08535	COG1294	oxidase, subunit
K8Z38_08540	COG4988	ABC transporter
K8Z38_08545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z38_08555	COG1216	Glycosyl transferase, family 2
K8Z38_08595	COG1686	Belongs to the peptidase S11 family
K8Z38_08610	COG0791	NLP P60 protein
K8Z38_08610	COG1388	LysM domain
K8Z38_08620	COG1132	(ABC) transporter
K8Z38_08625	COG0745	RESPONSE REGULATOR receiver
K8Z38_08630	COG5002	protein histidine kinase activity
K8Z38_08635	COG0300	oxidoreductase activity
K8Z38_08665	COG0460	homoserine dehydrogenase
K8Z38_08690	COG1316	TRANSCRIPTIONal
K8Z38_08705	COG0745	RESPONSE REGULATOR receiver
K8Z38_08710	COG5002	protein histidine kinase activity
K8Z38_08725	COG1285	pathogenesis
K8Z38_08730	COG1247	-acetyltransferase
K8Z38_08760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z38_08770	COG1082	Xylose isomerase domain protein TIM barrel
K8Z38_08780	COG2814	Major facilitator Superfamily
K8Z38_08785	COG1279	arginine transmembrane transporter activity
K8Z38_08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_08800	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z38_08835	COG0577	efflux transmembrane transporter activity
K8Z38_08840	COG2002	toxin-antitoxin pair type II binding
K8Z38_08845	COG1404	Belongs to the peptidase S8 family
K8Z38_08850	COG0640	Transcriptional regulator
K8Z38_08855	COG0667	Aldo Keto reductase
K8Z38_08860	COG2814	Major facilitator Superfamily
K8Z38_08865	COG3152	Membrane
K8Z38_08890	COG0840	transmembrane signaling receptor activity
K8Z38_08905	COG3949	Membrane
K8Z38_08910	COG0783	Belongs to the Dps family
K8Z38_08925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z38_08935	COG1231	oxidoreductase activity
K8Z38_08940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_08945	COG4989	oxidoreductase activity
K8Z38_08955	COG0523	cobalamin synthesis protein
K8Z38_08960	COG0456	acetyltransferase
K8Z38_08965	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z38_08975	COG0702	epimerase
K8Z38_08985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z38_08995	COG4166	transmembrane transport
K8Z38_09020	COG5337	Spore coat protein CotH
K8Z38_09025	COG1051	belongs to the nudix hydrolase family
K8Z38_09030	COG0586	Pfam SNARE associated Golgi protein
K8Z38_09045	COG0701	Predicted permease
K8Z38_09050	COG3689	TIGRFAM TIGR03943 family protein
K8Z38_09055	COG1607	acyl-coa hydrolase
K8Z38_09065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z38_09080	COG0702	epimerase
K8Z38_09085	COG2839	Protein conserved in bacteria
K8Z38_09090	COG1253	flavin adenine dinucleotide binding
K8Z38_09110	COG1114	Component of the transport system for branched-chain amino acids
K8Z38_09115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z38_09135	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z38_09145	COG1876	peptidase activity
K8Z38_09160	COG2211	Major facilitator Superfamily
K8Z38_09175	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z38_09185	COG0561	phosphatase activity
K8Z38_09200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z38_09215	COG1819	glycosyl
K8Z38_09220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_09225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_09255	COG0456	acetyltransferase
K8Z38_09290	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z38_09355	COG3874	Sporulation protein YtfJ
K8Z38_09380	COG2226	methyltransferase
K8Z38_09405	COG1082	Xylose isomerase domain protein TIM barrel
K8Z38_09410	COG0346	lactoylglutathione lyase activity
K8Z38_09425	COG1595	DNA-templated transcription, initiation
K8Z38_09440	COG0426	domain, Protein
K8Z38_09440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z38_09450	COG0386	Belongs to the glutathione peroxidase family
K8Z38_09460	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z38_09465	COG0714	Associated with various cellular activities
K8Z38_09470	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z38_09475	COG1140	nitrate reductase beta subunit
K8Z38_09480	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z38_09485	COG2181	nitrate reductase activity
K8Z38_09490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z38_09495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z38_09500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z38_09505	COG0303	'Molybdopterin
K8Z38_09510	COG0314	molybdopterin synthase activity
K8Z38_09515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K8Z38_09520	COG2223	nitrite transmembrane transporter activity
K8Z38_09530	COG1648	precorrin-2 dehydrogenase activity
K8Z38_09540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z38_09540	COG1587	Uroporphyrinogen-III synthase
K8Z38_09545	COG2146	nitrite reductase [NAD(P)H] activity
K8Z38_09550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z38_09555	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z38_09590	COG2359	stage V sporulation protein S
K8Z38_09640	COG0457	Tetratricopeptide repeat
K8Z38_09655	COG1418	mRNA catabolic process
K8Z38_09660	COG0488	(ABC) transporter
K8Z38_09705	COG1476	TRANSCRIPTIONal
K8Z38_09725	COG0629	single-stranded DNA binding
K8Z38_09735	COG1413	lyase activity
K8Z38_09750	COG2136	Putative SAM-dependent methyltransferase
K8Z38_09750	COG2521	methyltransferase
K8Z38_09755	COG0018	arginyl-trna synthetase
K8Z38_09810	COG0017	Asparaginyl-tRNA synthetase
K8Z38_09840	COG2610	gluconate transmembrane transporter activity
K8Z38_09850	COG1794	racemase activity, acting on amino acids and derivatives
K8Z38_09860	COG0456	acetyltransferase
K8Z38_09870	COG3655	Transcriptional regulator
K8Z38_09875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z38_09885	COG1131	(ABC) transporter
K8Z38_09890	COG4473	ABC transporter
K8Z38_09900	COG0546	phosphoglycolate phosphatase activity
K8Z38_09915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z38_09930	COG0768	penicillin binding
K8Z38_09940	COG0204	Acyl-transferase
K8Z38_09950	COG1272	protein, Hemolysin III
K8Z38_09960	COG0805	protein transport
K8Z38_09970	COG1307	EDD domain protein, DegV family
K8Z38_09980	COG1999	signal sequence binding
K8Z38_09985	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z38_09990	COG0367	asparagine synthase
K8Z38_10005	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z38_10010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z38_10015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z38_10035	COG1335	isochorismatase
K8Z38_10050	COG0668	transmembrane transport
K8Z38_10055	COG2203	Gaf domain
K8Z38_10055	COG4585	Histidine kinase
K8Z38_10060	COG2197	response regulator
K8Z38_10065	COG1737	Transcriptional regulator
K8Z38_10070	COG0384	phenazine biosynthesis protein PhzF
K8Z38_10075	COG1064	alcohol dehydrogenase
K8Z38_10100	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z38_10135	COG1125	glycine betaine transport
K8Z38_10135	COG0517	IMP dehydrogenase activity
K8Z38_10140	COG1174	glycine betaine transport
K8Z38_10175	COG1253	flavin adenine dinucleotide binding
K8Z38_10180	COG1012	belongs to the aldehyde dehydrogenase family
K8Z38_10185	COG5506	Protein of unknown function (DUF1694)
K8Z38_10200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z38_10205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z38_10210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z38_10215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z38_10220	COG0456	acetyltransferase
K8Z38_10225	COG3829	transcription factor binding
K8Z38_10230	COG1509	lysine 2,3-aminomutase activity
K8Z38_10265	COG4991	sh3 domain protein
K8Z38_10265	COG3064	Membrane
K8Z38_10265	COG0515	serine threonine protein kinase
K8Z38_10275	COG0671	phosphoesterase, PA-phosphatase related
K8Z38_10280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z38_10285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z38_10370	COG0300	oxidoreductase activity
K8Z38_10390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z38_10390	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z38_10400	COG2814	Major facilitator Superfamily
K8Z38_10405	COG4841	protein insertion into membrane
K8Z38_10410	COG0372	Belongs to the citrate synthase family
K8Z38_10415	COG2079	MmgE PrpD family protein
K8Z38_10420	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z38_10425	COG1960	acyl-CoA dehydrogenase activity
K8Z38_10430	COG2084	Dehydrogenase
K8Z38_10440	COG1280	lysine exporter protein (LysE YggA)
K8Z38_10445	COG1024	Enoyl-CoA hydratase
K8Z38_10460	COG0420	3'-5' exonuclease activity
K8Z38_10465	COG0419	ATPase involved in DNA repair
K8Z38_10485	COG2223	nitrite transmembrane transporter activity
K8Z38_10490	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_10495	COG1169	isochorismate synthase
K8Z38_10500	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z38_10505	COG3433	isochorismatase activity
K8Z38_10505	COG1535	isochorismatase
K8Z38_10510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z38_10515	COG3251	PFAM MbtH domain protein
K8Z38_10520	COG2814	Major facilitator Superfamily
K8Z38_10535	COG0776	regulation of translation
K8Z38_10545	COG2318	DinB family
K8Z38_10555	COG1115	amino acid carrier protein
K8Z38_10570	COG2329	Antibiotic biosynthesis monooxygenase
K8Z38_10575	COG1187	pseudouridine synthase activity
K8Z38_10580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z38_10585	COG1136	(ABC) transporter
K8Z38_10600	COG0028	Belongs to the TPP enzyme family
K8Z38_10640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z38_10665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_10700	COG1247	-acetyltransferase
K8Z38_10725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z38_10735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_10770	COG0583	DNA-binding transcription factor activity
K8Z38_10775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z38_10795	COG0583	DNA-binding transcription factor activity
K8Z38_10800	COG2258	MOSC domain
K8Z38_10815	COG1132	(ABC) transporter
K8Z38_10820	COG1132	(ABC) transporter
K8Z38_10845	COG1396	sequence-specific DNA binding
K8Z38_10915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z38_10920	COG1595	DNA-templated transcription, initiation
K8Z38_10945	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z38_10970	COG2971	BadF BadG BcrA BcrD
K8Z38_10990	COG1846	Transcriptional regulator
K8Z38_11010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_11030	COG1309	transcriptional regulator
K8Z38_11055	COG0500	methyltransferase
K8Z38_11055	COG3615	Tellurite resistance protein tehB
K8Z38_11065	COG2226	methyltransferase
K8Z38_11070	COG3961	Belongs to the TPP enzyme family
K8Z38_11075	COG1846	Transcriptional regulator
K8Z38_11105	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z38_11130	COG2002	toxin-antitoxin pair type II binding
K8Z38_11140	COG0730	response to heat
K8Z38_11145	COG0110	maltose O-acetyltransferase activity
K8Z38_11150	COG1686	Belongs to the peptidase S11 family
K8Z38_11165	COG2814	Major facilitator Superfamily
K8Z38_11235	COG0741	lytic transglycosylase activity
K8Z38_11240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_11245	COG2239	Acts as a magnesium transporter
K8Z38_11355	COG1396	sequence-specific DNA binding
K8Z38_11375	COG1309	transcriptional regulator
K8Z38_11380	COG0367	asparagine synthase
K8Z38_11405	COG1760	l-serine dehydratase
K8Z38_11410	COG1760	l-serine dehydratase
K8Z38_11415	COG0814	amino acid
K8Z38_11435	COG1533	DNA photolyase activity
K8Z38_11445	COG0076	glutamate decarboxylase activity
K8Z38_11455	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z38_11490	COG0772	Belongs to the SEDS family
K8Z38_11495	COG2239	Acts as a magnesium transporter
K8Z38_11505	COG0768	penicillin binding
K8Z38_11510	COG1595	DNA-templated transcription, initiation
K8Z38_11520	COG0768	penicillin binding
K8Z38_11525	COG0768	penicillin binding
K8Z38_11540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_11555	COG1131	(ABC) transporter
K8Z38_11565	COG0582	viral genome integration into host DNA
K8Z38_11575	COG3620	sequence-specific DNA binding
K8Z38_11605	COG1484	DNA-dependent DNA replication
K8Z38_11620	COG2002	toxin-antitoxin pair type II binding
K8Z38_11675	COG0582	viral genome integration into host DNA
K8Z38_11730	COG0740	serine-type endopeptidase activity
K8Z38_11805	COG4824	toxin secretion phage lysis holin
K8Z38_11845	COG1309	transcriptional regulator
K8Z38_11860	COG1960	acyl-CoA dehydrogenase activity
K8Z38_11865	COG0439	Biotin carboxylase
K8Z38_11870	COG0511	ligase activity, forming carbon-carbon bonds
K8Z38_11875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z38_11880	COG1024	Enoyl-CoA hydratase
K8Z38_11885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z38_11890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z38_11910	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z38_11925	COG0572	uridine kinase
K8Z38_11945	COG1686	Belongs to the peptidase S11 family
K8Z38_11970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z38_11985	COG3227	Zinc metalloprotease (Elastase)
K8Z38_11990	COG2207	Transcriptional regulator
K8Z38_12035	COG1942	4-Oxalocrotonate Tautomerase
K8Z38_12040	COG0583	DNA-binding transcription factor activity
K8Z38_12050	COG1131	(ABC) transporter
K8Z38_12080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_12085	COG2368	4-hydroxyphenylacetate
K8Z38_12110	COG2323	membrane
K8Z38_12115	COG0693	protein deglycase activity
K8Z38_12125	COG3386	PFAM SMP-30 Gluconolaconase
K8Z38_12135	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z38_12140	COG3773	Cell wall hydrolase
K8Z38_12150	COG0745	RESPONSE REGULATOR receiver
K8Z38_12155	COG2205	protein histidine kinase activity
K8Z38_12160	COG0488	(ABC) transporter
K8Z38_12170	COG1136	(ABC) transporter
K8Z38_12175	COG0577	efflux transmembrane transporter activity
K8Z38_12195	COG0460	homoserine dehydrogenase
K8Z38_12200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_12210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z38_12280	COG2124	cytochrome p450
K8Z38_12315	COG0561	phosphatase activity
K8Z38_12320	COG5002	protein histidine kinase activity
K8Z38_12325	COG0768	penicillin binding
K8Z38_12335	COG1819	glycosyl
K8Z38_12340	COG1794	racemase activity, acting on amino acids and derivatives
K8Z38_12365	COG2205	protein histidine kinase activity
K8Z38_12370	COG0582	viral genome integration into host DNA
K8Z38_12415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z38_12430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z38_12440	COG0745	RESPONSE REGULATOR receiver
K8Z38_12445	COG5002	protein histidine kinase activity
K8Z38_12450	COG0604	alcohol dehydrogenase
K8Z38_12455	COG0671	phosphoesterase, PA-phosphatase related
K8Z38_12460	COG0768	penicillin binding
K8Z38_12515	COG2814	Major facilitator Superfamily
K8Z38_12520	COG2814	Major facilitator Superfamily
K8Z38_12535	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z38_12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_12555	COG0697	spore germination
K8Z38_12590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z38_12600	COG2223	nitrite transmembrane transporter activity
K8Z38_12615	COG0592	DNA-directed DNA polymerase activity
K8Z38_12650	COG3878	Protein conserved in bacteria
K8Z38_12670	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z38_12710	COG0322	excinuclease ABC activity
K8Z38_12730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z38_12760	COG1011	Hydrolase
K8Z38_12765	COG0745	RESPONSE REGULATOR receiver
K8Z38_12770	COG5002	protein histidine kinase activity
K8Z38_12785	COG1136	(ABC) transporter
K8Z38_12790	COG0577	efflux transmembrane transporter activity
K8Z38_12795	COG1073	alpha beta
K8Z38_12800	COG0657	acetylesterase activity
K8Z38_12805	COG0076	glutamate decarboxylase activity
K8Z38_12820	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z38_12825	COG3227	Zinc metalloprotease (Elastase)
K8Z38_12830	COG0737	Belongs to the 5'-nucleotidase family
K8Z38_12845	COG0201	protein transport
K8Z38_12850	COG0697	spore germination
K8Z38_12855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_12890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_12905	COG2959	enzyme of heme biosynthesis
K8Z38_12945	COG1309	transcriptional regulator
K8Z38_12975	COG3284	Transcriptional regulator
K8Z38_13010	COG1959	2 iron, 2 sulfur cluster binding
K8Z38_13025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z38_13030	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z38_13035	COG0022	dehydrogenase e1 component
K8Z38_13040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z38_13050	COG2814	Major facilitator Superfamily
K8Z38_13060	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_13065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z38_13065	COG0456	acetyltransferase
K8Z38_13105	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z38_13110	COG4175	Glycine betaine
K8Z38_13110	COG0517	IMP dehydrogenase activity
K8Z38_13140	COG2153	protein acetylation
K8Z38_13145	COG3397	chitin binding
K8Z38_13150	COG1819	glycosyl
K8Z38_13170	COG2205	protein histidine kinase activity
K8Z38_13175	COG2226	methyltransferase
K8Z38_13180	COG2315	Protein conserved in bacteria
K8Z38_13225	COG0456	acetyltransferase
K8Z38_13230	COG3973	AAA domain
K8Z38_13240	COG2105	PFAM AIG2 family protein
K8Z38_13245	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z38_13285	COG4637	Psort location Cytoplasmic, score
K8Z38_13300	COG3397	chitin binding
K8Z38_13315	COG1162	GTPase activity
K8Z38_13320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z38_13325	COG1115	amino acid carrier protein
K8Z38_13330	COG1012	belongs to the aldehyde dehydrogenase family
K8Z38_13335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z38_13345	COG3938	Belongs to the proline racemase family
K8Z38_13350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z38_13390	COG0586	Pfam SNARE associated Golgi protein
K8Z38_13400	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z38_13410	COG4166	transmembrane transport
K8Z38_13420	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z38_13435	COG0667	Aldo Keto reductase
K8Z38_13480	COG3850	Histidine kinase
K8Z38_13480	COG5002	protein histidine kinase activity
K8Z38_13485	COG0745	RESPONSE REGULATOR receiver
K8Z38_13505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z38_13515	COG1164	Oligoendopeptidase f
K8Z38_13520	COG1307	EDD domain protein, DegV family
K8Z38_13565	COG2814	Major facilitator Superfamily
K8Z38_13575	COG1664	Polymer-forming cytoskeletal
K8Z38_13580	COG0789	Transcriptional regulator
K8Z38_13585	COG4533	DNA binding
K8Z38_13590	COG0477	Major facilitator Superfamily
K8Z38_13590	COG2814	Major facilitator Superfamily
K8Z38_13615	COG2261	transglycosylase associated protein
K8Z38_13630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K8Z38_13665	COG0436	Aminotransferase
K8Z38_13670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z38_13680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8Z38_13695	COG1131	(ABC) transporter
K8Z38_13745	COG0628	permease
K8Z38_13760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z38_13765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z38_13770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z38_13800	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z38_13820	COG0697	spore germination
K8Z38_13850	COG4912	Dna alkylation repair
K8Z38_13855	COG0346	lactoylglutathione lyase activity
K8Z38_13860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_13870	COG0861	Integral membrane protein TerC family
K8Z38_13880	COG1368	sulfuric ester hydrolase activity
K8Z38_13885	COG0488	(ABC) transporter
K8Z38_13900	COG1033	growth of symbiont in host cell
K8Z38_13900	COG2409	Drug exporters of the RND superfamily
K8Z38_13905	COG1309	transcriptional regulator
K8Z38_13920	COG0287	Prephenate dehydrogenase
K8Z38_13935	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z38_13935	COG1605	Chorismate mutase
K8Z38_13980	COG3584	3D domain protein
K8Z38_13980	COG1388	LysM domain
K8Z38_13995	COG0277	FAD linked oxidase domain protein
K8Z38_14010	COG1879	ABC-type sugar transport system periplasmic component
K8Z38_14020	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z38_14030	COG2390	Transcriptional regulator
K8Z38_14035	COG1070	Carbohydrate kinase
K8Z38_14060	COG2329	Antibiotic biosynthesis monooxygenase
K8Z38_14080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z38_14100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z38_14105	COG4187	Peptidase family M20/M25/M40
K8Z38_14110	COG1414	Transcriptional regulator
K8Z38_14115	COG0833	amino acid
K8Z38_14125	COG3239	Fatty acid desaturase
K8Z38_14135	COG2720	vancomycin resistance protein
K8Z38_14140	COG1785	Belongs to the alkaline phosphatase family
K8Z38_14150	COG3655	Transcriptional regulator
K8Z38_14170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_14175	COG0346	lactoylglutathione lyase activity
K8Z38_14195	COG0714	Associated with various cellular activities
K8Z38_14240	COG0463	Glycosyl transferase, family 2
K8Z38_14260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z38_14265	COG0753	catalase activity
K8Z38_14305	COG0714	Associated with various cellular activities
K8Z38_14395	COG0778	Nitroreductase
K8Z38_14400	COG1846	Transcriptional regulator
K8Z38_14420	COG3831	ATPase activity
K8Z38_14420	COG4884	unkown
K8Z38_14445	COG0037	tRNA processing
K8Z38_14445	COG0590	tRNA wobble adenosine to inosine editing
K8Z38_14455	COG0456	acetyltransferase
K8Z38_14470	COG0697	spore germination
K8Z38_14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_14515	COG0730	response to heat
K8Z38_14525	COG0833	amino acid
K8Z38_14570	COG0768	penicillin binding
K8Z38_14605	COG1984	allophanate hydrolase subunit 2
K8Z38_14610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z38_14615	COG1414	Transcriptional regulator
K8Z38_14625	COG3142	Participates in the control of copper homeostasis
K8Z38_14630	COG0640	Transcriptional regulator
K8Z38_14640	COG1960	acyl-CoA dehydrogenase activity
K8Z38_14655	COG3314	Sporulation integral membrane protein YlbJ
K8Z38_14665	COG0454	-acetyltransferase
K8Z38_14675	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z38_14700	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z38_14700	COG3848	Pyruvate phosphate dikinase
K8Z38_14720	COG1522	sequence-specific DNA binding
K8Z38_14725	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_14730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_14750	COG1063	alcohol dehydrogenase
K8Z38_14755	COG5002	protein histidine kinase activity
K8Z38_14780	COG2207	Transcriptional regulator
K8Z38_14800	COG0737	Belongs to the 5'-nucleotidase family
K8Z38_14805	COG2267	carboxylic ester hydrolase activity
K8Z38_14810	COG1335	isochorismatase
K8Z38_14835	COG2801	Transposase and inactivated derivatives
K8Z38_14840	COG0583	DNA-binding transcription factor activity
K8Z38_14850	COG2814	Major facilitator Superfamily
K8Z38_14885	COG0598	Magnesium transport protein CorA
K8Z38_14960	COG0657	acetylesterase activity
K8Z38_14965	COG0288	reversible hydration of carbon dioxide
K8Z38_14975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z38_14980	COG5609	conserved protein (DUF2294)
K8Z38_14990	COG0456	acetyltransferase
K8Z38_14995	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z38_15005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_15015	COG0798	PFAM Bile acid sodium symporter
K8Z38_15020	COG0346	lactoylglutathione lyase activity
K8Z38_15025	COG0640	Transcriptional regulator
K8Z38_15030	COG2814	Major facilitator Superfamily
K8Z38_15035	COG1309	transcriptional regulator
K8Z38_15040	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_15045	COG1522	sequence-specific DNA binding
K8Z38_15065	COG0346	lactoylglutathione lyase activity
K8Z38_15160	COG2814	Major facilitator Superfamily
K8Z38_15175	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z38_15185	COG1690	Belongs to the RtcB family
K8Z38_15195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z38_15215	COG0577	efflux transmembrane transporter activity
K8Z38_15220	COG5002	protein histidine kinase activity
K8Z38_15220	COG3850	Histidine kinase
K8Z38_15230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_15260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z38_15290	COG3831	ATPase activity
K8Z38_15305	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_15305	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_15385	COG5444	nuclease activity
K8Z38_15410	COG1876	peptidase activity
K8Z38_15415	COG2843	Capsule synthesis protein
K8Z38_15425	COG0477	Major facilitator Superfamily
K8Z38_15440	COG1846	Transcriptional regulator
K8Z38_15445	COG2814	Major facilitator Superfamily
K8Z38_15460	COG2031	fatty acid transporter
K8Z38_15470	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z38_15525	COG1288	antiporter activity
K8Z38_15545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z38_15555	COG1733	regulation of RNA biosynthetic process
K8Z38_15560	COG0778	Nitroreductase
K8Z38_15570	COG0469	pyruvate kinase activity
K8Z38_15590	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_15600	COG1131	(ABC) transporter
K8Z38_15625	COG1011	Hydrolase
K8Z38_15635	COG2365	Tyrosine phosphatase family
K8Z38_15670	COG0628	permease
K8Z38_15695	COG0500	methyltransferase
K8Z38_15705	COG0477	Major facilitator Superfamily
K8Z38_15735	COG1253	flavin adenine dinucleotide binding
K8Z38_15740	COG0789	Transcriptional regulator
K8Z38_15750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z38_15780	COG0697	spore germination
K8Z38_15790	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z38_15795	COG3813	Protein conserved in bacteria
K8Z38_15800	COG2706	6-phosphogluconolactonase activity
K8Z38_15805	COG1070	Carbohydrate kinase
K8Z38_15815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z38_15820	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z38_15825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z38_15830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z38_15855	COG0840	transmembrane signaling receptor activity
K8Z38_15865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z38_15865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z38_15870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z38_15870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z38_15875	COG1733	regulation of RNA biosynthetic process
K8Z38_15890	COG0814	amino acid
K8Z38_15920	COG2188	Transcriptional regulator
K8Z38_15925	COG0673	inositol 2-dehydrogenase activity
K8Z38_15945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_15965	COG0384	phenazine biosynthesis protein PhzF
K8Z38_15985	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_15990	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z38_16000	COG1733	regulation of RNA biosynthetic process
K8Z38_16025	COG1191	sigma factor activity
K8Z38_16080	COG1151	hydroxylamine reductase activity
K8Z38_16145	COG1113	amino acid transport
K8Z38_16150	COG2814	Major facilitator Superfamily
K8Z38_16185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z38_16190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z38_16200	COG1247	-acetyltransferase
K8Z38_16205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z38_16210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_16215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_16220	COG3739	integral membrane protein
K8Z38_16245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_16260	COG0583	DNA-binding transcription factor activity
K8Z38_16270	COG2890	protein-(glutamine-N5) methyltransferase activity
K8Z38_16285	COG1193	negative regulation of DNA recombination
K8Z38_16295	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z38_16300	COG1164	Oligoendopeptidase f
K8Z38_16330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z38_16360	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z38_16370	COG0640	Transcriptional regulator
K8Z38_16375	COG0604	alcohol dehydrogenase
K8Z38_16385	COG0457	Tetratricopeptide repeat
K8Z38_16395	COG0385	Bile acid
K8Z38_16400	COG0277	FAD linked oxidase domain protein
K8Z38_16425	COG1183	phosphatidylcholine synthase activity
K8Z38_16430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_16430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z38_16435	COG1252	NADH dehydrogenase
K8Z38_16445	COG0823	Involved in the tonB-independent uptake of proteins
K8Z38_16450	COG3397	chitin binding
K8Z38_16460	COG0697	spore germination
K8Z38_16490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z38_16500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z38_16510	COG0457	Tetratricopeptide repeat
K8Z38_16545	COG1404	Belongs to the peptidase S8 family
K8Z38_16575	COG0488	(ABC) transporter
K8Z38_16600	COG3852	Histidine kinase
K8Z38_16610	COG1285	pathogenesis
K8Z38_16620	COG2514	catechol 2,3-dioxygenase activity
K8Z38_16625	COG2720	vancomycin resistance protein
K8Z38_16660	COG0716	FMN binding
K8Z38_16695	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_16705	COG0165	Argininosuccinate lyase
K8Z38_16720	COG4145	pantothenate transmembrane transporter activity
K8Z38_16730	COG1012	belongs to the aldehyde dehydrogenase family
K8Z38_16735	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_16745	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z38_16750	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z38_16755	COG2962	Rard protein
K8Z38_16760	COG3326	Membrane
K8Z38_16775	COG0489	protein tyrosine kinase activity
K8Z38_16785	COG0314	molybdopterin synthase activity
K8Z38_16790	COG0303	'Molybdopterin
K8Z38_16795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z38_16800	COG2116	formate transmembrane transporter activity
K8Z38_16810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z38_16815	COG5609	conserved protein (DUF2294)
K8Z38_16820	COG2427	Protein of unknown function (DUF1641)
K8Z38_16825	COG3383	formate dehydrogenase (NAD+) activity
K8Z38_16830	COG0697	spore germination
K8Z38_16845	COG0531	amino acid
K8Z38_16880	COG2226	methyltransferase
K8Z38_16885	COG4166	transmembrane transport
K8Z38_16890	COG4166	transmembrane transport
K8Z38_16895	COG4166	transmembrane transport
K8Z38_16900	COG1316	TRANSCRIPTIONal
K8Z38_16910	COG1595	DNA-templated transcription, initiation
K8Z38_16920	COG1131	(ABC) transporter
K8Z38_16940	COG0673	inositol 2-dehydrogenase activity
K8Z38_16945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z38_16950	COG0187	DNA topoisomerase II activity
K8Z38_16955	COG1832	CoA-binding protein
K8Z38_16960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z38_16965	COG0745	RESPONSE REGULATOR receiver
K8Z38_16975	COG1328	CTP reductase activity
K8Z38_16975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K8Z38_16985	COG4841	protein insertion into membrane
K8Z38_16990	COG0824	Thioesterase
K8Z38_17025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z38_17040	COG1132	(ABC) transporter
K8Z38_17050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z38_17080	COG2211	Major facilitator Superfamily
K8Z38_17090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z38_17105	COG0183	Belongs to the thiolase family
K8Z38_17110	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_17115	COG1268	BioY protein
K8Z38_17120	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_17125	COG1396	sequence-specific DNA binding
K8Z38_17155	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K8Z38_17175	COG0830	nickel cation binding
K8Z38_17215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_17225	COG5002	protein histidine kinase activity
K8Z38_17230	COG0400	carboxylic ester hydrolase activity
K8Z38_17235	COG0346	lactoylglutathione lyase activity
K8Z38_17245	COG0069	glutamate synthase activity
K8Z38_17250	COG1902	pentaerythritol trinitrate reductase activity
K8Z38_17255	COG1329	Transcriptional regulator
K8Z38_17260	COG0010	Belongs to the arginase family
K8Z38_17285	COG2226	methyltransferase
K8Z38_17310	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z38_17315	COG0785	Cytochrome C biogenesis protein
K8Z38_17325	COG1473	amidohydrolase
K8Z38_17340	COG1131	(ABC) transporter
K8Z38_17355	COG0583	DNA-binding transcription factor activity
K8Z38_17365	COG1346	cytolysis
K8Z38_17380	COG0730	response to heat
K8Z38_17405	COG1132	(ABC) transporter
K8Z38_17410	COG1132	(ABC) transporter
K8Z38_17445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z38_17450	COG0737	Belongs to the 5'-nucleotidase family
K8Z38_17460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z38_17480	COG1695	Transcriptional regulator
K8Z38_17490	COG0174	glutamine synthetase
K8Z38_17495	COG0789	Transcriptional regulator
K8Z38_17500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z38_17505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z38_17510	COG2860	membrane
K8Z38_17520	COG0464	growth
K8Z38_17550	COG1388	LysM domain
K8Z38_17550	COG3584	3D domain protein
K8Z38_17560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z38_17560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z38_17560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z38_17565	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z38_17570	COG1349	DNA-binding transcription factor activity
K8Z38_17575	COG1979	alcohol dehydrogenase
K8Z38_17580	COG2322	membrane
K8Z38_17590	COG1113	amino acid transport
K8Z38_17605	COG2116	formate transmembrane transporter activity
K8Z38_17620	COG2217	Heavy metal translocating P-type atpase
K8Z38_17625	COG2608	mercury ion transmembrane transporter activity
K8Z38_17630	COG1937	Protein conserved in bacteria
K8Z38_17640	COG2819	hydrolase of the alpha beta superfamily
K8Z38_17645	COG1120	ATPase activity
K8Z38_17650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_17655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_17660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z38_17670	COG2169	Transcriptional regulator
K8Z38_17675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z38_17680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z38_17700	COG2267	carboxylic ester hydrolase activity
K8Z38_17705	COG5001	Diguanylate cyclase
K8Z38_17705	COG3300	MHYT domain
K8Z38_17725	COG1086	Polysaccharide biosynthesis protein
K8Z38_17745	COG1346	cytolysis
K8Z38_17755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_17770	COG2188	Transcriptional regulator
K8Z38_17775	COG2723	6-phospho-beta-galactosidase activity
K8Z38_17780	COG0823	Involved in the tonB-independent uptake of proteins
K8Z38_17785	COG1404	Belongs to the peptidase S8 family
K8Z38_17790	COG3773	Cell wall hydrolase
K8Z38_17800	COG1368	sulfuric ester hydrolase activity
K8Z38_17805	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z38_17830	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z38_17840	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z38_17845	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z38_17845	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z38_17855	COG2359	stage V sporulation protein S
K8Z38_17860	COG1692	metallophosphoesterase
K8Z38_17880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z38_17885	COG1426	Protein conserved in bacteria
K8Z38_17900	COG0300	oxidoreductase activity
K8Z38_17905	COG0612	Peptidase, M16
K8Z38_17910	COG0612	Peptidase, M16
K8Z38_17915	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z38_17920	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z38_17925	COG3845	ABC transporter
K8Z38_17930	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z38_17935	COG2188	Transcriptional regulator
K8Z38_17950	COG0740	serine-type endopeptidase activity
K8Z38_17960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z38_17970	COG0527	aspartate kinase activity
K8Z38_17975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z38_17980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z38_17985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z38_17990	COG1873	PFAM PRC-barrel domain
K8Z38_17995	COG0612	Peptidase, M16
K8Z38_18000	COG0726	polysaccharide deacetylase
K8Z38_18015	COG0196	riboflavin kinase activity
K8Z38_18025	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z38_18030	COG1550	Protein conserved in bacteria
K8Z38_18040	COG1358	cellular component organization or biogenesis
K8Z38_18045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z38_18050	COG0195	Participates in both transcription termination and antitermination
K8Z38_18070	COG0750	zinc metalloprotease
K8Z38_18080	COG4589	Belongs to the CDS family
K8Z38_18130	COG4974	Belongs to the 'phage' integrase family
K8Z38_18140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z38_18145	COG0758	DNA mediated transformation
K8Z38_18150	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z38_18190	COG1837	Belongs to the UPF0109 family
K8Z38_18200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z38_18210	COG0552	protein localization to endoplasmic reticulum
K8Z38_18215	COG1196	nuclear chromosome segregation
K8Z38_18225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z38_18230	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_18235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z38_18250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z38_18255	COG1461	Dihydroxyacetone kinase
K8Z38_18260	COG1302	Protein conserved in bacteria
K8Z38_18275	COG1564	THIamine pyrophosphokinase
K8Z38_18280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z38_18290	COG2815	serine threonine protein kinase
K8Z38_18290	COG0515	serine threonine protein kinase
K8Z38_18295	COG0631	protein serine/threonine phosphatase activity
K8Z38_18305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z38_18305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z38_18320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z38_18325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z38_18345	COG1561	YicC-like family, N-terminal region
K8Z38_18350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z38_18360	COG0006	proline dipeptidase activity
K8Z38_18375	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z38_18435	COG0564	pseudouridine synthase activity
K8Z38_18455	COG3599	regulation of cell shape
K8Z38_18460	COG2302	S4 RNA-binding domain
K8Z38_18465	COG0762	integral membrane protein
K8Z38_18475	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z38_18485	COG1873	PFAM PRC-barrel domain
K8Z38_18490	COG1191	sigma factor activity
K8Z38_18495	COG1191	sigma factor activity
K8Z38_18505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z38_18510	COG0849	cell division
K8Z38_18530	COG0772	Belongs to the SEDS family
K8Z38_18550	COG0768	penicillin binding
K8Z38_18555	COG0768	penicillin binding
K8Z38_18575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z38_18595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z38_18600	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z38_18635	COG4824	toxin secretion phage lysis holin
K8Z38_18710	COG0740	serine-type endopeptidase activity
K8Z38_18765	COG0582	viral genome integration into host DNA
K8Z38_18820	COG2002	toxin-antitoxin pair type II binding
K8Z38_18860	COG1396	sequence-specific DNA binding
K8Z38_18900	COG0582	viral genome integration into host DNA
K8Z38_18910	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z38_18915	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z38_18920	COG3314	Sporulation integral membrane protein YlbJ
K8Z38_18930	COG0742	ribosomal rna small subunit methyltransferase
K8Z38_18945	COG3679	Belongs to the UPF0342 family
K8Z38_18950	COG0406	alpha-ribazole phosphatase activity
K8Z38_18965	COG2340	Cysteine-rich secretory protein family
K8Z38_18980	COG3336	cytochrome c oxidase
K8Z38_19015	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z38_19020	COG0772	Belongs to the SEDS family
K8Z38_19030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z38_19035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z38_19045	COG4896	Protein conserved in bacteria
K8Z38_19060	COG1217	gtp-binding protein TYPA
K8Z38_19070	COG0483	inositol monophosphate 1-phosphatase activity
K8Z38_19090	COG1982	Orn Lys Arg decarboxylase major
K8Z38_19140	COG0022	dehydrogenase e1 component
K8Z38_19145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z38_19160	COG0561	phosphatase activity
K8Z38_19170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z38_19175	COG0569	domain protein
K8Z38_19195	COG0583	DNA-binding transcription factor activity
K8Z38_19200	COG0517	IMP dehydrogenase activity
K8Z38_19210	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z38_19220	COG4703	Protein of unknown function (DUF1797)
K8Z38_19235	COG2200	EAL domain
K8Z38_19240	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_19245	COG1408	metallophosphoesterase
K8Z38_19290	COG2814	Major facilitator Superfamily
K8Z38_19310	COG3209	COG3209 Rhs family protein
K8Z38_19320	COG2205	protein histidine kinase activity
K8Z38_19330	COG0436	Aminotransferase
K8Z38_19335	COG1609	Transcriptional regulator
K8Z38_19340	COG3833	ABC-type maltose transport systems, permease component
K8Z38_19345	COG1175	transmembrane transport
K8Z38_19350	COG2182	Extracellular solute-binding protein
K8Z38_19360	COG0366	Alpha amylase catalytic
K8Z38_19365	COG3842	ATPase activity
K8Z38_19400	COG0183	Belongs to the thiolase family
K8Z38_19430	COG1695	Transcriptional regulator
K8Z38_19435	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_19455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z38_19460	COG0436	Aminotransferase
K8Z38_19495	COG2084	Dehydrogenase
K8Z38_19505	COG2199	diguanylate cyclase activity
K8Z38_19510	COG0778	Nitroreductase
K8Z38_19535	COG2190	(PTS) system
K8Z38_19535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z38_19535	COG1263	PTS System
K8Z38_19540	COG3711	transcriptional antiterminator
K8Z38_19550	COG2188	Transcriptional regulator
K8Z38_19560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z38_19585	COG1547	Domain of unknown function (DUF309)
K8Z38_19590	COG0456	acetyltransferase
K8Z38_19595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z38_19600	COG4086	secreted protein
K8Z38_19605	COG0561	phosphatase activity
K8Z38_19610	COG0697	spore germination
K8Z38_19625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z38_19670	COG1686	Belongs to the peptidase S11 family
K8Z38_19675	COG1725	Transcriptional regulator
K8Z38_19680	COG1131	(ABC) transporter
K8Z38_19695	COG1846	Transcriptional regulator
K8Z38_19710	COG0598	Magnesium transport protein CorA
K8Z38_19735	COG4974	Belongs to the 'phage' integrase family
K8Z38_19745	COG0735	belongs to the Fur family
K8Z38_19750	COG1300	Membrane
K8Z38_19770	COG0667	Aldo Keto reductase
K8Z38_19775	COG0656	L-ascorbic acid biosynthetic process
K8Z38_19780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z38_19780	COG0456	acetyltransferase
K8Z38_19810	COG0596	Alpha beta hydrolase
K8Z38_19815	COG2056	Na+-H+ antiporter family
K8Z38_19820	COG1609	Transcriptional regulator
K8Z38_19825	COG0456	acetyltransferase
K8Z38_19830	COG1073	alpha beta
K8Z38_19845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z38_19845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z38_19850	COG0307	riboflavin synthase, alpha
K8Z38_19880	COG2226	methyltransferase
K8Z38_19880	COG1073	alpha beta
K8Z38_19895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z38_19905	COG1757	Na H antiporter
K8Z38_19910	COG0737	Belongs to the 5'-nucleotidase family
K8Z38_19920	COG1522	sequence-specific DNA binding
K8Z38_19965	COG0300	oxidoreductase activity
K8Z38_19970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_19975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z38_19980	COG1760	l-serine dehydratase
K8Z38_19985	COG1760	l-serine dehydratase
K8Z38_20015	COG1285	pathogenesis
K8Z38_20025	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z38_20030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_20045	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z38_20050	COG4129	membrane
K8Z38_20055	COG1126	abc transporter atp-binding protein
K8Z38_20060	COG0765	amino acid transport
K8Z38_20065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z38_20085	COG2323	membrane
K8Z38_20090	COG0772	Belongs to the SEDS family
K8Z38_20100	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z38_20105	COG0022	dehydrogenase e1 component
K8Z38_20110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z38_20115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z38_20130	COG0280	phosphate acetyltransferase
K8Z38_20135	COG3829	transcription factor binding
K8Z38_20135	COG3290	protein histidine kinase activity
K8Z38_20145	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z38_20150	COG3093	addiction module antidote protein HigA
K8Z38_20165	COG0750	zinc metalloprotease
K8Z38_20170	COG0497	DNA recombination
K8Z38_20180	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z38_20190	COG0142	geranyltranstransferase activity
K8Z38_20215	COG1302	Protein conserved in bacteria
K8Z38_20220	COG0439	Biotin carboxylase
K8Z38_20225	COG0511	ligase activity, forming carbon-carbon bonds
K8Z38_20270	COG3854	ATPases associated with a variety of cellular activities
K8Z38_20295	COG0006	proline dipeptidase activity
K8Z38_20310	COG3872	metal-dependent enzyme
K8Z38_20320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z38_20360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z38_20370	COG1609	Transcriptional regulator
K8Z38_20380	COG2076	Multidrug Resistance protein
K8Z38_20385	COG2076	Multidrug Resistance protein
K8Z38_20415	COG1131	(ABC) transporter
K8Z38_20420	COG1725	Transcriptional regulator
K8Z38_20450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z38_20535	COG4824	toxin secretion phage lysis holin
K8Z38_20610	COG0740	serine-type endopeptidase activity
K8Z38_20665	COG0582	viral genome integration into host DNA
K8Z38_20720	COG2002	toxin-antitoxin pair type II binding
K8Z38_20730	COG1484	DNA-dependent DNA replication
K8Z38_20755	COG3646	Phage regulatory protein
K8Z38_20765	COG1396	sequence-specific DNA binding
K8Z38_20810	COG1459	type II secretion system
K8Z38_20815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z38_20870	COG0646	methionine synthase
K8Z38_20870	COG1410	methionine synthase
K8Z38_20875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z38_20875	COG0646	methionine synthase
K8Z38_20880	COG0626	cystathionine gamma-synthase activity
K8Z38_20885	COG0626	cystathionine gamma-synthase activity
K8Z38_20905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_20915	COG1940	carbohydrate kinase activity
K8Z38_20920	COG4483	Protein conserved in bacteria
K8Z38_20925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z38_20930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z38_20935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z38_20940	COG0704	Plays a role in the regulation of phosphate uptake
K8Z38_20950	COG0573	inorganic phosphate transmembrane transporter activity
K8Z38_20955	COG0573	inorganic phosphate transmembrane transporter activity
K8Z38_20960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z38_20970	COG0768	penicillin binding
K8Z38_20975	COG0477	Major facilitator Superfamily
K8Z38_20980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z38_20990	COG5521	maltodextrose utilization protein MalA
K8Z38_21005	COG0735	belongs to the Fur family
K8Z38_21010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z38_21015	COG1121	(ABC) transporter
K8Z38_21020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_21050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z38_21055	COG2384	SAM-dependent methyltransferase
K8Z38_21065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z38_21070	COG0358	DNA primase activity
K8Z38_21085	COG0517	IMP dehydrogenase activity
K8Z38_21100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z38_21105	COG0295	cytidine deaminase activity
K8Z38_21110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z38_21120	COG1480	7TM receptor with intracellular HD hydrolase
K8Z38_21125	COG1702	phosphate starvation-inducible protein PhoH
K8Z38_21140	COG1610	YqeY-like protein
K8Z38_21145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z38_21150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z38_21155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z38_21185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z38_21190	COG1733	regulation of RNA biosynthetic process
K8Z38_21215	COG1466	dna polymerase III delta subunit
K8Z38_21225	COG0658	competence protein
K8Z38_21225	COG2333	competence protein COMEC
K8Z38_21230	COG2131	deaminase
K8Z38_21235	COG1596	polysaccharide export
K8Z38_21235	COG1555	photosystem II stabilization
K8Z38_21240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z38_21245	COG2226	methyltransferase
K8Z38_21250	COG0799	negative regulation of ribosome biogenesis
K8Z38_21255	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z38_21265	COG1534	Rna-binding protein
K8Z38_21275	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z38_21280	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z38_21315	COG0778	Nitroreductase
K8Z38_21320	COG2357	RelA SpoT domain protein
K8Z38_21330	COG1785	Belongs to the alkaline phosphatase family
K8Z38_21340	COG2267	carboxylic ester hydrolase activity
K8Z38_21385	COG3186	Phenylalanine-4-hydroxylase
K8Z38_21395	COG2514	catechol 2,3-dioxygenase activity
K8Z38_21400	COG2259	Doxx family
K8Z38_21440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z38_21450	COG1012	belongs to the aldehyde dehydrogenase family
K8Z38_21450	COG1454	alcohol dehydrogenase
K8Z38_21455	COG0626	cystathionine gamma-synthase activity
K8Z38_21460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z38_21510	COG0826	peptidase U32
K8Z38_21515	COG0826	peptidase U32
K8Z38_21520	COG4122	O-methyltransferase activity
K8Z38_21525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z38_21555	COG0628	permease
K8Z38_21575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z38_21590	COG1104	cysteine desulfurase activity
K8Z38_21595	COG1959	2 iron, 2 sulfur cluster binding
K8Z38_21600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z38_21610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z38_21635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z38_21645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z38_21645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z38_21650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z38_21655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z38_21655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z38_21665	COG2244	polysaccharide biosynthetic process
K8Z38_21670	COG2323	membrane
K8Z38_21680	COG1862	Preprotein translocase
K8Z38_21710	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z38_21740	COG0157	Belongs to the NadC ModD family
K8Z38_21745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z38_21750	COG1104	cysteine desulfurase activity
K8Z38_21755	COG1827	regulation of RNA biosynthetic process
K8Z38_21760	COG2258	MOSC domain
K8Z38_21765	COG0077	Prephenate dehydratase
K8Z38_21770	COG0577	efflux transmembrane transporter activity
K8Z38_21775	COG0577	efflux transmembrane transporter activity
K8Z38_21780	COG1136	(ABC) transporter
K8Z38_21785	COG5002	protein histidine kinase activity
K8Z38_21790	COG0745	RESPONSE REGULATOR receiver
K8Z38_21800	COG3290	protein histidine kinase activity
K8Z38_21810	COG2868	ribosomal protein
K8Z38_21820	COG1530	ribonuclease E activity
K8Z38_21825	COG1994	Peptidase M50
K8Z38_21830	COG0739	heme binding
K8Z38_21835	COG2894	cell division
K8Z38_21855	COG1077	Cell shape determining protein MreB Mrl
K8Z38_21880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K8Z38_21910	COG2003	Belongs to the UPF0758 family
K8Z38_21940	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_22055	COG1595	DNA-templated transcription, initiation
K8Z38_22065	COG3331	DNA recombination
K8Z38_22145	COG3646	Phage regulatory protein
K8Z38_22165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z38_22185	COG0285	dihydrofolate synthase activity
K8Z38_22200	COG1388	LysM domain
K8Z38_22210	COG0113	porphobilinogen synthase activity
K8Z38_22215	COG1587	Uroporphyrinogen-III synthase
K8Z38_22225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z38_22235	COG1846	Transcriptional regulator
K8Z38_22240	COG1764	response to oxidative stress
K8Z38_22255	COG1067	ATP-dependent peptidase activity
K8Z38_22255	COG0470	DNA polymerase III
K8Z38_22400	COG0622	Phosphoesterase
K8Z38_22415	COG5401	PFAM Sporulation and spore germination
K8Z38_22430	COG2197	response regulator
K8Z38_22435	COG2233	PERMEase
K8Z38_22440	COG0402	S-adenosylhomocysteine deaminase activity
K8Z38_22445	COG1983	PspC domain protein
K8Z38_22450	COG1396	sequence-specific DNA binding
K8Z38_22455	COG0697	spore germination
K8Z38_22465	COG1959	2 iron, 2 sulfur cluster binding
K8Z38_22470	COG1668	transmembrane transport
K8Z38_22475	COG4152	abc transporter atp-binding protein
K8Z38_22480	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z38_22485	COG1360	Flagellar Motor Protein
K8Z38_22490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z38_22495	COG1876	peptidase activity
K8Z38_22500	COG0824	Thioesterase
K8Z38_22505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z38_22510	COG1053	succinate dehydrogenase
K8Z38_22515	COG2009	succinate dehydrogenase
K8Z38_22520	COG1719	4-vinyl reductase, 4VR
K8Z38_22530	COG3118	belongs to the thioredoxin family
K8Z38_22535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z38_22540	COG2086	electron transfer activity
K8Z38_22545	COG1024	Enoyl-CoA hydratase
K8Z38_22550	COG1309	transcriptional regulator
K8Z38_22555	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_22580	COG2318	DinB family
K8Z38_22610	COG1131	(ABC) transporter
K8Z38_22615	COG2205	protein histidine kinase activity
K8Z38_22620	COG0745	RESPONSE REGULATOR receiver
K8Z38_22630	COG4895	conserved protein (DUF2196)
K8Z38_22635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z38_22645	COG4509	Sortase family
K8Z38_22650	COG1120	ATPase activity
K8Z38_22665	COG5386	Cell surface protein
K8Z38_22675	COG5386	Cell surface protein
K8Z38_22680	COG1114	Component of the transport system for branched-chain amino acids
K8Z38_22685	COG1187	pseudouridine synthase activity
K8Z38_22695	COG1796	DNA polymerase
K8Z38_22695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z38_22700	COG1286	toxin biosynthetic process
K8Z38_22745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z38_22755	COG1418	mRNA catabolic process
K8Z38_22775	COG2814	Major facilitator Superfamily
K8Z38_22780	COG1566	PFAM secretion protein HlyD family protein
K8Z38_22785	COG1309	transcriptional regulator
K8Z38_22790	COG1363	Peptidase, m42
K8Z38_22815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z38_22830	COG1484	DNA-dependent DNA replication
K8Z38_22835	COG3611	Membrane attachment protein
K8Z38_22845	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z38_22850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z38_22860	COG1971	Probably functions as a manganese efflux pump
K8Z38_22870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z38_22870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z38_22875	COG5002	protein histidine kinase activity
K8Z38_22880	COG0745	RESPONSE REGULATOR receiver
K8Z38_22900	COG0538	isocitrate dehydrogenase activity
K8Z38_22905	COG0372	Belongs to the citrate synthase family
K8Z38_22915	COG0628	permease
K8Z38_22920	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z38_22945	COG1725	Transcriptional regulator
K8Z38_22950	COG0281	malic enzyme
K8Z38_22955	COG0587	DNA-directed DNA polymerase activity
K8Z38_22970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z38_22985	COG4109	DRTGG domain
K8Z38_23000	COG0006	proline dipeptidase activity
K8Z38_23040	COG0662	Cupin 2, conserved barrel domain protein
K8Z38_23055	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_23060	COG0589	response to stress
K8Z38_23105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_23130	COG0827	DNA restriction-modification system
K8Z38_23135	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z38_23140	COG3874	Sporulation protein YtfJ
K8Z38_23155	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z38_23165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z38_23180	COG1104	cysteine desulfurase activity
K8Z38_23190	COG0583	DNA-binding transcription factor activity
K8Z38_23195	COG0697	spore germination
K8Z38_23200	COG1309	transcriptional regulator
K8Z38_23205	COG1956	GAF domain-containing protein
K8Z38_23210	COG0626	cystathionine gamma-synthase activity
K8Z38_23260	COG1595	DNA-templated transcription, initiation
K8Z38_23270	COG0110	maltose O-acetyltransferase activity
K8Z38_23275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z38_23280	COG0454	-acetyltransferase
K8Z38_23285	COG0517	IMP dehydrogenase activity
K8Z38_23290	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z38_23305	COG0745	RESPONSE REGULATOR receiver
K8Z38_23315	COG0666	response to abiotic stimulus
K8Z38_23320	COG0745	RESPONSE REGULATOR receiver
K8Z38_23320	COG2972	Histidine kinase
K8Z38_23340	COG3279	Response regulator of the LytR AlgR family
K8Z38_23375	COG1609	Transcriptional regulator
K8Z38_23380	COG1605	Chorismate mutase
K8Z38_23380	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z38_23385	COG4851	CamS sex pheromone cAM373 precursor
K8Z38_23390	COG3118	belongs to the thioredoxin family
K8Z38_23400	COG2309	aminopeptidase activity
K8Z38_23415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_23430	COG1674	ftsk spoiiie
K8Z38_23445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z38_23455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z38_23460	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z38_23465	COG1363	Peptidase, m42
K8Z38_23475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_23490	COG0510	thiamine kinase activity
K8Z38_23495	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z38_23505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z38_23510	COG1349	DNA-binding transcription factor activity
K8Z38_23515	COG1187	pseudouridine synthase activity
K8Z38_23520	COG2244	polysaccharide biosynthetic process
K8Z38_23525	COG2081	HI0933 family
K8Z38_23530	COG2814	Major facilitator Superfamily
K8Z38_23540	COG3832	glyoxalase III activity
K8Z38_23560	COG1329	Transcriptional regulator
K8Z38_23585	COG0314	molybdopterin synthase activity
K8Z38_23590	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z38_23595	COG0303	'Molybdopterin
K8Z38_23605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z38_23610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z38_23630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z38_23640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z38_23685	COG2814	Major facilitator Superfamily
K8Z38_23690	COG0475	glutathione-regulated potassium exporter activity
K8Z38_23695	COG0490	domain, Protein
K8Z38_23700	COG0582	viral genome integration into host DNA
K8Z38_23710	COG1136	(ABC) transporter
K8Z38_23730	COG1242	4 iron, 4 sulfur cluster binding
K8Z38_23735	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z38_23740	COG1794	racemase activity, acting on amino acids and derivatives
K8Z38_23760	COG2267	carboxylic ester hydrolase activity
K8Z38_23765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z38_23770	COG0671	phosphoesterase, PA-phosphatase related
K8Z38_23775	COG0438	transferase activity, transferring glycosyl groups
K8Z38_23795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_23835	COG0546	phosphoglycolate phosphatase activity
K8Z38_23840	COG1349	DNA-binding transcription factor activity
K8Z38_23855	COG5002	protein histidine kinase activity
K8Z38_23860	COG3852	Histidine kinase
K8Z38_23865	COG2267	carboxylic ester hydrolase activity
K8Z38_23870	COG1368	sulfuric ester hydrolase activity
K8Z38_23895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z38_23900	COG1116	anion transmembrane transporter activity
K8Z38_23905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z38_23930	COG0494	nUDIX hydrolase
K8Z38_23960	COG1854	S-ribosylhomocysteine lyase activity
K8Z38_23975	COG1271	oxidase subunit
K8Z38_23980	COG1294	oxidase, subunit
K8Z38_23990	COG2801	Transposase and inactivated derivatives
K8Z38_24005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_24025	COG1842	Phage shock protein A
K8Z38_24060	COG5002	protein histidine kinase activity
K8Z38_24065	COG0745	RESPONSE REGULATOR receiver
K8Z38_24090	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z38_24095	COG1597	lipid kinase activity
K8Z38_24120	COG0586	Pfam SNARE associated Golgi protein
K8Z38_24130	COG0577	efflux transmembrane transporter activity
K8Z38_24135	COG1136	(ABC) transporter
K8Z38_24140	COG3708	Transcriptional regulator
K8Z38_24140	COG2207	Transcriptional regulator
K8Z38_24150	COG5658	integral membrane protein
K8Z38_24155	COG0640	Transcriptional regulator
K8Z38_24160	COG0745	RESPONSE REGULATOR receiver
K8Z38_24165	COG2205	protein histidine kinase activity
K8Z38_24170	COG0577	efflux transmembrane transporter activity
K8Z38_24175	COG0577	efflux transmembrane transporter activity
K8Z38_24180	COG1136	(ABC) transporter
K8Z38_24185	COG0577	efflux transmembrane transporter activity
K8Z38_24215	COG2188	Transcriptional regulator
K8Z38_24235	COG3964	amidohydrolase
K8Z38_24255	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z38_24280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z38_24285	COG0596	Alpha beta hydrolase
K8Z38_24295	COG1169	isochorismate synthase
K8Z38_24300	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z38_24305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z38_24330	COG0058	SHG alpha-glucan phosphorylase activity
K8Z38_24340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z38_24460	COG0544	peptidyl-prolyl cis-trans isomerase activity
K8Z38_24495	COG1285	pathogenesis
K8Z38_24500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z38_24515	COG2155	Conserved Protein
K8Z38_24520	COG1098	S1 RNA binding domain
K8Z38_24525	COG0436	Aminotransferase
K8Z38_24535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z38_24540	COG2267	carboxylic ester hydrolase activity
K8Z38_24550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z38_24570	COG5018	Exonuclease
K8Z38_24575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z38_24600	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z38_24610	COG1268	BioY protein
K8Z38_24615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z38_24620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z38_24635	COG3584	3D domain protein
K8Z38_24650	COG1252	NADH dehydrogenase
K8Z38_24680	COG1683	Conserved Protein
K8Z38_24735	COG1388	LysM domain
K8Z38_24735	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_24735	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_24740	COG4824	toxin secretion phage lysis holin
K8Z38_24875	COG1191	sigma factor activity
K8Z38_24900	COG3646	Phage regulatory protein
K8Z38_24900	COG3645	SOS response
K8Z38_24915	COG3620	sequence-specific DNA binding
K8Z38_24955	COG0316	Belongs to the HesB IscA family
K8Z38_24970	COG1252	NADH dehydrogenase
K8Z38_24985	COG0390	transport system, permease component
K8Z38_24990	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z38_25035	COG4837	Protein of unknown function (DUF1462)
K8Z38_25040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z38_25050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z38_25055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z38_25075	COG1358	cellular component organization or biogenesis
K8Z38_25085	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z38_25090	COG0647	UMP catabolic process
K8Z38_25100	COG2445	Protein of unknown function DUF86
K8Z38_25105	COG1494	fructose-1,6-bisphosphatase
K8Z38_25125	COG4470	Protein conserved in bacteria
K8Z38_25135	COG0789	Transcriptional regulator
K8Z38_25140	COG4377	Putative membrane peptidase family (DUF2324)
K8Z38_25165	COG0739	heme binding
K8Z38_25175	COG3377	Domain of unknown function (DUF1805)
K8Z38_25180	COG0737	Belongs to the 5'-nucleotidase family
K8Z38_25185	COG2801	Transposase and inactivated derivatives
K8Z38_25210	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_25350	COG1396	sequence-specific DNA binding
K8Z38_25430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z38_25435	COG0582	viral genome integration into host DNA
K8Z38_25440	COG0719	Fe-S assembly protein
K8Z38_25445	COG0822	iron-sulfur transferase activity
K8Z38_25450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z38_25455	COG0719	Fe-S assembly protein
K8Z38_25460	COG0396	ATPase activity
K8Z38_25465	COG1464	Belongs to the NlpA lipoprotein family
K8Z38_25470	COG1464	Belongs to the NlpA lipoprotein family
K8Z38_25475	COG2011	ABC-type metal ion transport system permease component
K8Z38_25490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z38_25495	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z38_25505	COG1393	Belongs to the ArsC family
K8Z38_25525	COG0039	L-malate dehydrogenase activity
K8Z38_25540	COG1309	transcriptional regulator
K8Z38_25545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z38_25550	COG1960	acyl-CoA dehydrogenase activity
K8Z38_25555	COG0183	Belongs to the thiolase family
K8Z38_25560	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z38_25560	COG1024	Enoyl-CoA hydratase
K8Z38_25570	COG1686	Belongs to the peptidase S11 family
K8Z38_25585	COG0011	TIGRFAM Protein of
K8Z38_25590	COG0840	transmembrane signaling receptor activity
K8Z38_25605	COG2814	Major facilitator Superfamily
K8Z38_25610	COG0531	amino acid
K8Z38_25630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_25665	COG0586	Pfam SNARE associated Golgi protein
K8Z38_25675	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z38_25680	COG0745	RESPONSE REGULATOR receiver
K8Z38_25685	COG5002	protein histidine kinase activity
K8Z38_25715	COG0840	transmembrane signaling receptor activity
K8Z38_25720	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z38_25740	COG4974	Belongs to the 'phage' integrase family
K8Z38_25765	COG3227	Zinc metalloprotease (Elastase)
K8Z38_25785	COG0586	Pfam SNARE associated Golgi protein
K8Z38_25790	COG0475	glutathione-regulated potassium exporter activity
K8Z38_25795	COG0490	domain, Protein
K8Z38_25800	COG1115	amino acid carrier protein
K8Z38_25805	COG0783	Belongs to the Dps family
K8Z38_25820	COG1611	Belongs to the LOG family
K8Z38_25830	COG1528	Iron-storage protein
K8Z38_25835	COG2311	Membrane
K8Z38_25840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z38_25845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z38_25850	COG1115	amino acid carrier protein
K8Z38_25855	COG1115	amino acid carrier protein
K8Z38_25860	COG2910	NAD(P)H-binding
K8Z38_25875	COG0656	L-ascorbic acid biosynthetic process
K8Z38_25880	COG2814	Major facilitator Superfamily
K8Z38_25885	COG1733	regulation of RNA biosynthetic process
K8Z38_25895	COG1252	NADH dehydrogenase
K8Z38_25950	COG0488	(ABC) transporter
K8Z38_25955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_26000	COG0745	RESPONSE REGULATOR receiver
K8Z38_26040	COG0557	exoribonuclease II activity
K8Z38_26045	COG1647	Serine aminopeptidase, S33
K8Z38_26050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z38_26055	COG1346	cytolysis
K8Z38_26090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z38_26105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z38_26130	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_26130	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_26130	COG1388	LysM domain
K8Z38_26135	COG4824	toxin secretion phage lysis holin
K8Z38_26270	COG3331	DNA recombination
K8Z38_26360	COG3646	Phage regulatory protein
K8Z38_26390	COG0582	viral genome integration into host DNA
K8Z38_26415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z38_26430	COG2323	membrane
K8Z38_26440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z38_26450	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z38_26460	COG1051	belongs to the nudix hydrolase family
K8Z38_26470	COG0492	ferredoxin-NADP+ reductase activity
K8Z38_26475	COG0457	Tetratricopeptide repeat
K8Z38_26480	COG0110	maltose O-acetyltransferase activity
K8Z38_26500	COG1950	PFAM Membrane protein of
K8Z38_26510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z38_26515	COG0556	nucleotide-excision repair
K8Z38_26530	COG0789	Transcriptional regulator
K8Z38_26550	COG0583	DNA-binding transcription factor activity
K8Z38_26560	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z38_26565	COG0488	(ABC) transporter
K8Z38_26575	COG1132	(ABC) transporter
K8Z38_26580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z38_26585	COG0793	Belongs to the peptidase S41A family
K8Z38_26585	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_26590	COG2177	Part of the ABC transporter FtsEX involved in
K8Z38_26595	COG2884	Cell division ATP-binding protein ftsE
K8Z38_26620	COG1131	(ABC) transporter
K8Z38_26650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z38_26655	COG1278	Cold shock
K8Z38_26660	COG1040	competence protein
K8Z38_26665	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z38_26670	COG1388	LysM domain
K8Z38_26670	COG0791	NLP P60 protein
K8Z38_26675	COG1733	regulation of RNA biosynthetic process
K8Z38_26680	COG1307	EDD domain protein, DegV family
K8Z38_26685	COG1739	Uncharacterized protein family UPF0029
K8Z38_26690	COG1316	TRANSCRIPTIONal
K8Z38_26695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z38_26700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z38_26705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z38_26715	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z38_26715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z38_26735	COG1486	melibiose metabolic process
K8Z38_26740	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z38_26745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z38_26755	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z38_26765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z38_26770	COG1301	dicarboxylic acid transport
K8Z38_26785	COG1511	domain protein
K8Z38_26790	COG0583	DNA-binding transcription factor activity
K8Z38_26795	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K8Z38_26805	COG1271	oxidase subunit
K8Z38_26810	COG1294	oxidase, subunit
K8Z38_26815	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z38_26825	COG1620	l-lactate permease
K8Z38_26840	COG2389	metal-binding protein
K8Z38_26850	COG1368	sulfuric ester hydrolase activity
K8Z38_26865	COG0791	NLP P60 protein
K8Z38_26865	COG1388	LysM domain
K8Z38_26870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z38_26885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z38_26890	COG1388	LysM domain
K8Z38_26890	COG3584	3D domain protein
K8Z38_26915	COG4715	Zinc finger, swim domain protein
K8Z38_26920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z38_26960	COG0577	efflux transmembrane transporter activity
K8Z38_26965	COG1136	(ABC) transporter
K8Z38_26990	COG5002	protein histidine kinase activity
K8Z38_26995	COG0745	RESPONSE REGULATOR receiver
K8Z38_27005	COG1316	TRANSCRIPTIONal
K8Z38_27010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z38_27015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z38_27020	COG1215	transferase activity, transferring glycosyl groups
K8Z38_27025	COG0463	Glycosyl transferase, family 2
K8Z38_27030	COG0438	transferase activity, transferring glycosyl groups
K8Z38_27040	COG1216	Glycosyl transferase, family 2
K8Z38_27055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z38_27060	COG4464	protein tyrosine phosphatase activity
K8Z38_27065	COG0489	protein tyrosine kinase activity
K8Z38_27070	COG3944	biosynthesis protein
K8Z38_27075	COG0489	protein tyrosine kinase activity
K8Z38_27090	COG1609	Transcriptional regulator
K8Z38_27100	COG0739	heme binding
K8Z38_27115	COG3279	Response regulator of the LytR AlgR family
K8Z38_27120	COG2385	sporulation resulting in formation of a cellular spore
K8Z38_27135	COG4836	Membrane
K8Z38_27140	COG1007	ATP synthesis coupled electron transport
K8Z38_27145	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z38_27150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z38_27160	COG0839	Belongs to the complex I subunit 6 family
K8Z38_27180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z38_27195	COG3300	MHYT domain
K8Z38_27195	COG5001	Diguanylate cyclase
K8Z38_27245	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z38_27280	COG0698	ribose 5-phosphate isomerase
K8Z38_27295	COG2259	Doxx family
K8Z38_27300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z38_27315	COG0009	L-threonylcarbamoyladenylate synthase
K8Z38_27350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z38_27355	COG1494	fructose-1,6-bisphosphatase
K8Z38_27375	COG4821	SIS domain
K8Z38_27385	COG3343	RNA polymerase activity
K8Z38_27395	COG1960	acyl-CoA dehydrogenase activity
K8Z38_27400	COG1960	acyl-CoA dehydrogenase activity
K8Z38_27405	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z38_27410	COG0183	Belongs to the thiolase family
K8Z38_27415	COG0247	lactate metabolic process
K8Z38_27415	COG2181	nitrate reductase activity
K8Z38_27420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z38_27430	COG5001	Diguanylate cyclase
K8Z38_27430	COG3300	MHYT domain
K8Z38_27445	COG3227	Zinc metalloprotease (Elastase)
K8Z38_27450	COG2197	response regulator
K8Z38_27455	COG4585	Histidine kinase
K8Z38_27460	COG0842	Transport permease protein
K8Z38_27465	COG1131	(ABC) transporter
K8Z38_27470	COG0024	Methionine aminopeptidase
K8Z38_27490	COG2234	aminopeptidase activity
K8Z38_27510	COG1595	DNA-templated transcription, initiation
K8Z38_27520	COG4506	Protein conserved in bacteria
K8Z38_27525	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z38_27550	COG2814	Major facilitator Superfamily
K8Z38_27555	COG0789	Transcriptional regulator
K8Z38_27560	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z38_27565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z38_27575	COG1994	Peptidase M50
K8Z38_27585	COG1078	dGTPase activity
K8Z38_27590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z38_27600	COG2801	Transposase and inactivated derivatives
K8Z38_27605	COG1120	ATPase activity
K8Z38_27610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_27615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z38_27635	COG0280	phosphate acetyltransferase
K8Z38_27650	COG3773	Cell wall hydrolase
K8Z38_27660	COG2363	Small membrane protein
K8Z38_27670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z38_27675	COG2233	PERMEase
K8Z38_27680	COG0561	phosphatase activity
K8Z38_27685	COG2814	Major facilitator Superfamily
K8Z38_27700	COG1131	(ABC) transporter
K8Z38_27705	COG2755	lipolytic protein G-D-S-L family
K8Z38_27710	COG1609	Transcriptional regulator
K8Z38_27720	COG0460	homoserine dehydrogenase
K8Z38_27730	COG2873	o-acetylhomoserine
K8Z38_27740	COG1011	Hydrolase
K8Z38_27745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z38_27755	COG2197	response regulator
K8Z38_27760	COG4585	Histidine kinase
K8Z38_27760	COG2203	Gaf domain
K8Z38_27765	COG0351	phosphomethylpyrimidine kinase
K8Z38_27770	COG3706	GGDEF domain
K8Z38_27775	COG2879	small protein
K8Z38_27780	COG1966	Carbon starvation protein
K8Z38_27785	COG3279	Response regulator of the LytR AlgR family
K8Z38_27790	COG0477	Major facilitator Superfamily
K8Z38_27800	COG0438	transferase activity, transferring glycosyl groups
K8Z38_27815	COG0840	transmembrane signaling receptor activity
K8Z38_27825	COG1607	acyl-coa hydrolase
K8Z38_27830	COG1216	Glycosyl transferase, family 2
K8Z38_27845	COG1216	Glycosyl transferase, family 2
K8Z38_27855	COG4485	Bacterial membrane protein, YfhO
K8Z38_27860	COG0463	Glycosyl transferase, family 2
K8Z38_27865	COG0488	(ABC) transporter
K8Z38_27870	COG1309	transcriptional regulator
K8Z38_27875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z38_27885	COG0628	permease
K8Z38_27905	COG3275	phosphorelay sensor kinase activity
K8Z38_27910	COG2814	Major facilitator Superfamily
K8Z38_27915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z38_27950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z38_27955	COG1272	protein, Hemolysin III
K8Z38_27990	COG5002	protein histidine kinase activity
K8Z38_28005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z38_28010	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z38_28015	COG4853	Protein conserved in bacteria
K8Z38_28025	COG5002	protein histidine kinase activity
K8Z38_28030	COG0745	RESPONSE REGULATOR receiver
K8Z38_28060	COG0305	Participates in initiation and elongation during chromosome replication
K8Z38_28070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z38_28075	COG4241	membrane
K8Z38_28095	COG0012	GTP binding
K8Z38_28100	COG4481	Protein conserved in bacteria
K8Z38_28105	COG0668	transmembrane transport
K8Z38_28115	COG1475	DNA binding
K8Z38_28120	COG1192	Involved in chromosome partitioning
K8Z38_28145	COG1847	R3H domain protein
K8Z38_28160	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z38_28170	COG0592	DNA-directed DNA polymerase activity
K8Z38_28175	COG2501	S4 domain
K8Z38_28185	COG0187	DNA topoisomerase II activity
K8Z38_28190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z38_28225	COG0516	GMP reductase activity
K8Z38_28225	COG0517	IMP dehydrogenase activity
K8Z38_28230	COG1686	Belongs to the peptidase S11 family
K8Z38_28260	COG1428	Deoxynucleoside kinase
K8Z38_28265	COG1428	Deoxynucleoside kinase
K8Z38_28270	COG1335	isochorismatase
K8Z38_28275	COG0590	tRNA wobble adenosine to inosine editing
K8Z38_28285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z38_28340	COG1982	Orn Lys Arg decarboxylase major
K8Z38_28350	COG0470	DNA polymerase III
K8Z38_28355	COG1774	PSP1 C-terminal conserved region
K8Z38_28365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z38_28375	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z38_28380	COG2002	toxin-antitoxin pair type II binding
K8Z38_28390	COG0084	hydrolase, TatD family'
K8Z38_28410	COG4466	Protein conserved in bacteria
K8Z38_28425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z38_28430	COG0251	oxidation-reduction process
K8Z38_28460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z38_28465	COG2002	toxin-antitoxin pair type II binding
K8Z38_28470	COG2244	polysaccharide biosynthetic process
K8Z38_28475	COG3956	TIGRFAM MazG family protein
K8Z38_28480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z38_28500	COG1098	S1 RNA binding domain
K8Z38_28515	COG2208	phosphoserine phosphatase activity
K8Z38_28525	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z38_28530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z38_28545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z38_28550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z38_28555	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z38_28560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z38_28565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z38_28570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z38_28575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z38_28580	COG1396	sequence-specific DNA binding
K8Z38_28585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z38_28675	COG3880	PFAM UvrB UvrC protein
K8Z38_28685	COG0542	response to heat
K8Z38_28690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z38_28700	COG4956	integral membrane protein (PIN domain superfamily)
K8Z38_28720	COG1045	serine acetyltransferase
K8Z38_28735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z38_28740	COG3688	RNA-binding protein containing a PIN domain
K8Z38_28755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z38_28760	COG0250	Participates in transcription elongation, termination and antitermination
K8Z38_28765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z38_28785	COG2813	Specifically methylates the guanine in position
K8Z38_28800	COG1358	cellular component organization or biogenesis
K8Z38_28805	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z38_28870	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z38_28930	COG0201	protein transport
K8Z38_28940	COG0024	Methionine aminopeptidase
K8Z38_28950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z38_28985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z38_29010	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z38_29015	COG0489	protein tyrosine kinase activity
K8Z38_29025	COG2194	sulfuric ester hydrolase activity
K8Z38_29030	COG0726	polysaccharide deacetylase
K8Z38_29110	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z38_29115	COG4856	YbbR-like protein
K8Z38_29150	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_29155	COG2011	ABC-type metal ion transport system permease component
K8Z38_29160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z38_29165	COG1464	Belongs to the NlpA lipoprotein family
K8Z38_29170	COG0604	alcohol dehydrogenase
K8Z38_29180	COG0277	FAD linked oxidase domain protein
K8Z38_29185	COG2271	Major facilitator Superfamily
K8Z38_29195	COG2814	Major facilitator Superfamily
K8Z38_29215	COG2207	Transcriptional regulator
K8Z38_29230	COG4166	transmembrane transport
K8Z38_29235	COG4166	transmembrane transport
K8Z38_29240	COG0656	L-ascorbic acid biosynthetic process
K8Z38_29255	COG4149	molybdate abc transporter
K8Z38_29260	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z38_29265	COG1910	domain protein
K8Z38_29280	COG0697	spore germination
K8Z38_29295	COG0204	Acyl-transferase
K8Z38_29305	COG1609	Transcriptional regulator
K8Z38_29315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_29335	COG5298	Protein conserved in bacteria
K8Z38_29355	COG0488	(ABC) transporter
K8Z38_29365	COG0747	negative chemotaxis
K8Z38_29370	COG0601	transmembrane transport
K8Z38_29375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z38_29380	COG0444	Belongs to the ABC transporter superfamily
K8Z38_29385	COG4608	Belongs to the ABC transporter superfamily
K8Z38_29395	COG0561	phosphatase activity
K8Z38_29415	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z38_29420	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z38_29430	COG0531	amino acid
K8Z38_29435	COG2814	Major facilitator Superfamily
K8Z38_29445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z38_29455	COG4294	response to UV
K8Z38_29460	COG0705	Rhomboid family
K8Z38_29470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z38_29475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z38_29480	COG0864	Transcriptional regulator
K8Z38_29485	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z38_29490	COG2183	response to ionizing radiation
K8Z38_29590	COG0802	atpase or kinase
K8Z38_29595	COG1214	PFAM Peptidase M22, glycoprotease
K8Z38_29600	COG0456	acetyltransferase
K8Z38_29610	COG0488	(ABC) transporter
K8Z38_29625	COG1266	CAAX protease self-immunity
K8Z38_29645	COG0582	viral genome integration into host DNA
K8Z38_29790	COG3331	DNA recombination
K8Z38_29870	COG2233	PERMEase
K8Z38_29875	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z38_29880	COG0288	reversible hydration of carbon dioxide
K8Z38_29885	COG1522	sequence-specific DNA binding
K8Z38_29915	COG0542	response to heat
K8Z38_29920	COG0494	nUDIX hydrolase
K8Z38_29925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K8Z38_29940	COG0457	Tetratricopeptide repeat
K8Z38_30075	COG3344	reverse transcriptase
K8Z38_30095	COG3344	reverse transcriptase
K8Z38_30280	COG3344	reverse transcriptase
K8Z38_30295	COG2814	Major facilitator Superfamily
K8Z38_30330	COG3344	reverse transcriptase
K8Z38_30350	COG3344	reverse transcriptase
K8Z38_30410	COG2311	Membrane
K8Z38_30470	COG2801	Transposase and inactivated derivatives
K8Z38_30475	COG0457	Tetratricopeptide repeat
K8Z38_30495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z38_30525	COG2002	toxin-antitoxin pair type II binding
K8Z38_30530	COG4166	transmembrane transport
K8Z38_30550	COG4974	Belongs to the 'phage' integrase family
K8Z38_30580	COG0583	DNA-binding transcription factor activity
K8Z38_30585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_30590	COG0402	S-adenosylhomocysteine deaminase activity
K8Z38_30665	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z38_30685	COG4824	toxin secretion phage lysis holin
K8Z38_30730	COG0840	transmembrane signaling receptor activity
K8Z38_30740	COG3300	MHYT domain
K8Z38_30740	COG5001	Diguanylate cyclase
K8Z38_30745	COG4974	Belongs to the 'phage' integrase family
K8Z38_30760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z38_30775	COG1073	alpha beta
K8Z38_30790	COG3104	oligopeptide transport
K8Z38_30820	COG0457	Tetratricopeptide repeat
K8Z38_30840	COG4974	Belongs to the 'phage' integrase family
K8Z38_30920	COG1132	(ABC) transporter
K8Z38_30925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z38_30935	COG1131	(ABC) transporter
K8Z38_30955	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8Z38_30995	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_30995	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_31005	COG3227	Zinc metalloprotease (Elastase)
K8Z38_31020	COG3011	Protein conserved in bacteria
K8Z38_31035	COG0457	Tetratricopeptide repeat
K8Z38_31070	COG1132	(ABC) transporter
K8Z38_31090	COG1475	DNA binding
K8Z38_31145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z38_31150	COG3321	synthase
K8Z38_31150	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_31150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z38_31150	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_31150	COG0300	oxidoreductase activity
K8Z38_31165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z38_31170	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z38_31185	COG1960	acyl-CoA dehydrogenase activity
K8Z38_31205	COG3321	synthase
K8Z38_31205	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_31205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z38_31205	COG0300	oxidoreductase activity
K8Z38_31205	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_31205	COG3321	synthase
K8Z38_31205	COG0300	oxidoreductase activity
K8Z38_31205	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z38_31205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z38_31205	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z38_31260	COG0667	Aldo Keto reductase
K8Z38_31285	COG1396	sequence-specific DNA binding
K8Z38_31300	COG1216	Glycosyl transferase, family 2
K8Z38_31305	COG1024	Enoyl-CoA hydratase
K8Z38_31325	COG1484	DNA-dependent DNA replication
K8Z38_31480	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_31500	COG0739	heme binding
K8Z38_31505	COG0741	lytic transglycosylase activity
K8Z38_31535	COG1361	Conserved repeat domain
K8Z38_31540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z38_31545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K8Z38_31550	COG1687	branched-chain amino acid
K8Z38_31585	COG3344	reverse transcriptase
K8Z38_31630	COG2311	Membrane
K8Z38_31650	COG0457	Tetratricopeptide repeat
K8Z38_31675	COG0583	DNA-binding transcription factor activity
K8Z38_31680	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z38_31725	COG0730	response to heat
K8Z38_31750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z38_31775	COG2002	toxin-antitoxin pair type II binding
K8Z38_31780	COG4166	transmembrane transport
K8Z38_31800	COG4974	Belongs to the 'phage' integrase family
K8Z38_31870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K8Z38_31875	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z38_31890	COG4824	toxin secretion phage lysis holin
K8Z38_31915	COG5444	nuclease activity
K8Z38_31990	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_31990	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_31995	COG0475	glutathione-regulated potassium exporter activity
K8Z38_32000	COG0490	domain, Protein
K8Z38_32005	COG0840	transmembrane signaling receptor activity
K8Z38_32060	COG0583	DNA-binding transcription factor activity
K8Z38_32070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z38_32105	COG0640	Transcriptional regulator
K8Z38_32145	COG0675	Transposase, IS605 OrfB family
K8Z38_32155	COG2828	Protein conserved in bacteria
K8Z38_32190	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z38_32225	COG0457	Tetratricopeptide repeat
K8Z38_32245	COG3344	reverse transcriptase
K8Z38_32330	COG1136	(ABC) transporter
K8Z38_32585	COG0592	DNA-directed DNA polymerase activity
K8Z38_32590	COG4712	double-strand break repair protein
K8Z38_32625	COG3344	reverse transcriptase
K8Z38_32635	COG3344	reverse transcriptase
K8Z38_32880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z38_32920	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_32920	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_33060	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z38_33130	COG1476	TRANSCRIPTIONal
K8Z38_33135	COG2197	response regulator
K8Z38_33145	COG1073	alpha beta
K8Z38_33195	COG3344	reverse transcriptase
K8Z38_33220	COG0791	NLP P60 protein
K8Z38_33220	COG0741	lytic transglycosylase activity
K8Z38_33475	COG0457	Tetratricopeptide repeat
K8Z38_33550	COG0739	heme binding
K8Z38_33720	COG0741	lytic transglycosylase activity
K8Z38_33720	COG0791	NLP P60 protein
K8Z38_33930	COG1923	regulation of RNA biosynthetic process
K8Z38_33940	COG0457	Tetratricopeptide repeat
K8Z38_34110	COG3728	DNA packaging
K8Z38_34110	COG5484	DNA packaging
K8Z38_34235	COG1674	ftsk spoiiie
K8Z38_34260	COG1396	sequence-specific DNA binding
K8Z38_34350	COG3331	DNA recombination
K8Z38_34425	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z38_34425	COG3409	Peptidoglycan-binding domain 1 protein
K8Z38_34425	COG1388	LysM domain
K8Z38_34480	COG1396	sequence-specific DNA binding
K8Z38_34625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z38_34765	COG3344	reverse transcriptase
K8Z38_34770	COG3654	unkown
K8Z38_34780	COG0582	viral genome integration into host DNA
K8Z38_34835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD