locus-tag class description BTG_00010 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BTG_00015 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BTG_00035 ENOG4105VB6 UPF0109 protein BTG_00060 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BTG_00075 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BTG_00080 ENOG4105C79 DNA protecting protein DprA BTG_00085 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BTG_00095 ENOG4108HE4 integrase family BTG_00125 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BTG_00135 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BTG_00140 ENOG4105KNE Phosphatidate cytidylyltransferase BTG_00145 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BTG_00150 ENOG4105DZP Membrane-associated zinc metalloprotease BTG_00160 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BTG_00170 ENOG4105CHV Transcription elongation factor NusA BTG_00175 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BTG_00180 ENOG4105VHM ribosomal protein BTG_00190 ENOG4105W7A Protein of unknown function (DUF503) BTG_00205 ENOG4105DTN riboflavin biosynthesis protein ribF BTG_00225 ENOG4105C1V Peptidase, M16 BTG_00235 ENOG4105E35 Dipicolinate synthase subunit A BTG_00240 ENOG4108S0H Dipicolinic acid synthetase, b subunit BTG_00245 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BTG_00255 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BTG_00265 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BTG_00275 ENOG4105CNU cell division protein FtsK BTG_00280 ENOG4105FDP GntR family transcriptional regulator BTG_00285 ENOG4105DIH basic membrane BTG_00290 ENOG4108JQ9 ABC transporter BTG_00295 ENOG4105UIB (ABC) transporter BTG_00315 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BTG_00320 ENOG4105XZV Protein of unknown function (DUF3243) BTG_00335 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BTG_00355 ENOG4105D48 metallophosphoesterase BTG_00360 ENOG4105MCT stage V sporulation protein S BTG_00365 ENOG4108IGT Dipeptidase BTG_00370 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BTG_00375 ENOG4105DQU oxidoreductase, subunit beta BTG_00420 ENOG4108IMY Transcriptional regulator BTG_00435 ENOG4107VMI polysaccharide deacetylase BTG_00440 ENOG4105C8Q Methyl-accepting chemotaxis BTG_00445 ENOG4105DQ6 Transposase BTG_00470 ENOG4105NA0 Transcriptional regulator BTG_00495 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BTG_00500 ENOG4105CZV ABC transporter BTG_00555 ENOG410890F Dynamin family BTG_00560 ENOG4105E0M Sulfatase BTG_00570 ENOG4105F0V Cell wall hydrolase BTG_00580 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C BTG_00585 ENOG4105C8Q Methyl-accepting chemotaxis BTG_00610 ENOG41067MG lrgb family BTG_00625 ENOG4105C5E polysaccharide biosynthesis protein BTG_00645 ENOG4105BZU Histidine kinase BTG_00675 ENOG4105D03 DNA-3-methyladenine glycosylase II BTG_00695 ENOG4105CGK Exodeoxyribonuclease III BTG_00715 ENOG4105E0A ABC, transporter BTG_00720 ENOG4105NIV Esterase BTG_00740 ENOG4105VPX protein, conserved in bacteria BTG_00745 ENOG410681U heavy metal transport detoxification protein BTG_00750 ENOG4105C59 p-type ATPase BTG_00760 ENOG4105K70 DNA-binding protein BTG_00765 ENOG4105TMB Formate nitrite transporter BTG_00785 ENOG4105C85 amino acid BTG_00800 ENOG4108SJC Membrane BTG_00805 ENOG4107QW4 alcohol dehydrogenase BTG_00810 ENOG4105E98 transcriptional regulator DeoR family BTG_00815 ENOG4105DE4 1-phosphofructokinase BTG_00820 ENOG4105DM4 PTS System BTG_00825 ENOG41069ER domain protein BTG_00855 ENOG4106F1P AAA ATPase, central domain protein BTG_00865 ENOG4105EN6 Membrane BTG_00870 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BTG_00875 ENOG4105CXI aluminum resistance protein BTG_00880 ENOG4105KV4 Transcriptional regulator BTG_00885 ENOG4105C5F glutamine synthetase BTG_00890 ENOG4105K7K Transcriptional regulator BTG_00910 ENOG4108SVB resolvase BTG_00920 ENOG4105CGH 5'-nucleotidase BTG_00960 ENOG4105BZ1 (ABC) transporter BTG_00965 ENOG4105BZ1 (ABC) transporter BTG_01005 ENOG41067MG lrgb family BTG_01010 ENOG4105VAW lrga family BTG_01015 ENOG4107RSM transcriptional regulator BTG_01035 ENOG4105CJ1 ABC, transporter BTG_01045 ENOG4105CH2 amidohydrolase BTG_01060 ENOG4107QIV Cytochrome c biogenesis protein BTG_01115 ENOG4108903 Formimidoylglutamase BTG_01120 ENOG4108VJ1 Transcriptional regulator (CarD family BTG_01125 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BTG_01130 ENOG4105CBC glutamate synthase BTG_01135 ENOG4105CK7 Sodium proline symporter BTG_01140 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BTG_01145 ENOG4105FBA Phospholipase Carboxylesterase BTG_01150 ENOG4105BZU Histidine kinase BTG_01160 ENOG4107AYK membrAne BTG_01195 ENOG4108IMY Transcriptional regulator BTG_01210 ENOG4105CEY Amp-dependent synthetase and ligase BTG_01215 ENOG4107ZYJ bioY protein BTG_01220 ENOG4107F3J Amp-dependent synthetase and ligase BTG_01240 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BTG_01250 ENOG4105E5W Transporter BTG_01280 ENOG4108I0Z Aconitate hydratase BTG_01285 ENOG4108JJA ABC, transporter BTG_01295 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BTG_01300 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BTG_01325 ENOG4105W8X HesB YadR YfhF-family protein BTG_01330 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BTG_01335 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BTG_01345 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_01350 ENOG4105C0H protease BTG_01355 ENOG4105K4P CoA-binding domain protein BTG_01360 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BTG_01370 ENOG4105D9R oxidoreductase BTG_01390 ENOG4105CIG ABC transporter BTG_01400 ENOG4105EMN RNA polymerase sigma factor BTG_01410 ENOG4108KGH TRANSCRIPTIONal BTG_01415 ENOG4107QJT sodium dicarboxylate symporter BTG_01485 ENOG4105CUB amino acid BTG_01515 ENOG4108JB9 formate dehydrogenase BTG_01525 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BTG_01530 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BTG_01540 ENOG4105TMB Formate nitrite transporter BTG_01545 ENOG4105D06 uba thif-type nad fad binding protein BTG_01550 ENOG4105CVM Molybdenum cofactor synthesis domain protein BTG_01555 ENOG4108ZAF Molybdopterin BTG_01565 ENOG4105D1F ATP-binding protein BTG_01580 ENOG410696E Membrane BTG_01585 ENOG4105FR1 rard protein BTG_01595 ENOG4105EWU Squalene--hopene cyclase BTG_01605 ENOG4105CHR reductase BTG_01610 ENOG4105C26 Dehydrogenase BTG_01620 ENOG4108IA2 Sodium pantothenate symporter BTG_01635 ENOG4106IQC argininosuccinate lyase BTG_01645 ENOG410904N short-chain dehydrogenase reductase BTG_01665 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BTG_01685 ENOG4105VEQ Cold shock protein BTG_01705 ENOG4108R1P BTG_01760 ENOG4108R1P BTG_01770 ENOG41073R8 VanW family BTG_01780 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BTG_01790 ENOG4105KT7 mgtC SapB transporter BTG_01800 ENOG4105BZU Histidine kinase BTG_01820 ENOG4107DUR UPF0457 protein BTG_01825 ENOG4108VXD carboxy-peptidase BTG_01845 ENOG41067SE Tetr family transcriptional regulator BTG_01850 ENOG4105C5H ABC transporter BTG_01855 ENOG4105BZU Histidine kinase BTG_01915 ENOG4105FAW cDP-glucose 4,6-dehydratase BTG_01955 ENOG4105E1K spore germination protein BTG_01970 ENOG4108M1A Chitin-binding protein BTG_01975 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C BTG_02000 ENOG4105C5E polysaccharide biosynthesis protein BTG_02005 ENOG4105C1B dTDP-glucose 4-6-dehydratase BTG_02010 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BTG_02015 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) BTG_02030 ENOG4105D2T synthase BTG_02035 ENOG4105CNI cell division protein FtsW BTG_02045 ENOG4105CNI cell division protein FtsW BTG_02065 ENOG4105CEP NADH dehydrogenase BTG_02085 ENOG4105CQB FAD linked oxidase domain protein BTG_02090 ENOG4105C09 Bile acid BTG_02115 ENOG4105CIS alcohol dehydrogenase BTG_02120 ENOG41082BM Transcriptional regulator, arsr family BTG_02130 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BTG_02145 ENOG4105E5T Major Facilitator Superfamily BTG_02155 ENOG4108A04 Beta-lactamase BTG_02160 ENOG4105DPN Oligoendopeptidase f BTG_02165 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BTG_02170 ENOG4105E5K Alpha-amylase BTG_02180 ENOG4105C98 muts2 protein BTG_02200 ENOG4107V2S Transcriptional regulator BTG_02210 ENOG4107CUJ Protein of unknown function (DUF2690) BTG_02230 ENOG4105NX3 Membrane BTG_02235 ENOG4105DQ5 transport system permease protein BTG_02240 ENOG4105EHG Permease protein BTG_02245 ENOG4108MES Periplasmic binding protein BTG_02255 ENOG4105WCN acetyltransferase BTG_02265 ENOG4107R3E Citrate transporter BTG_02275 ENOG4108TN2 lmbE family BTG_02310 ENOG4105CIS alcohol dehydrogenase BTG_02345 ENOG4105H3G oxidoreductase BTG_02380 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BTG_02440 ENOG4108ZJ4 polysaccharide deacetylase BTG_02460 ENOG4107SCK Monooxygenase BTG_02470 ENOG4105KVH Transcriptional regulator BTG_02475 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BTG_02490 ENOG4105JAB phenazine biosynthesis protein, phzf family BTG_02540 ENOG4105KVH Transcriptional regulator BTG_02545 ENOG4105D9R oxidoreductase BTG_02550 ENOG4108TZY GntR Family Transcriptional Regulator BTG_02555 ENOG4105KVH Transcriptional regulator BTG_02590 ENOG4105C44 Serine transporter BTG_02605 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BTG_02610 ENOG4105CV1 Transketolase (EC 2.2.1.1) BTG_02620 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BTG_02625 ENOG4105CMG Carbohydrate kinase BTG_02630 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BTG_02635 ENOG4105XDF Protein of unknown function (DUF1272) BTG_02640 ENOG4105DDN Pentapeptide repeat-containing protein BTG_02665 ENOG4105C37 (CBS) domain BTG_02690 ENOG4105EV4 Multidrug resistance protein mdtH BTG_02740 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BTG_02745 ENOG4105C31 Tryptophanyl-tRNA synthetase BTG_02750 ENOG4108UW5 maltose o-acetyltransferase BTG_02755 ENOG4106UW1 Major Facilitator superfamily BTG_02760 ENOG4105DKQ ROK family BTG_02765 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BTG_02830 ENOG4108PSK reductase BTG_02865 ENOG4108RCM Nitroreductase BTG_02870 ENOG4105KVH Transcriptional regulator BTG_02890 ENOG4108Z66 YbaK ebsC protein BTG_02895 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BTG_02905 ENOG4108K8S endonuclease I BTG_02965 ENOG4105DYS nad(p)h dehydrogenase (quinone) BTG_02975 ENOG4105CRW Short chain fatty acid transporter BTG_02990 ENOG4105CZM Major Facilitator BTG_02995 ENOG4107MII Sugar-specific transcriptional regulator TrmB BTG_03010 ENOG4108ISG Major Facilitator BTG_03020 ENOG4105PNM synthesis protein BTG_03025 ENOG4108VXD carboxy-peptidase BTG_03130 ENOG4108IG5 Transcriptional regulator BTG_03140 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BTG_03165 ENOG410874W AraC family transcriptional regulator BTG_03170 ENOG41082W1 Cupin 2, conserved barrel domain protein BTG_03185 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BTG_03190 ENOG4108JQ1 Dehydrogenase BTG_03220 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BTG_03230 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BTG_03235 ENOG4108U05 Transcriptional regulator BTG_03250 ENOG4105BZU Histidine kinase BTG_03255 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BTG_03275 ENOG4105JQZ Methyltransferase BTG_03295 ENOG4105K6H D-cysteine desulfhydrase BTG_03310 ENOG4105C0R drug resistance transporter emrb qaca subfamily BTG_03315 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BTG_03345 ENOG4105C19 ABC transporter BTG_03355 ENOG4105DNP FAD linked oxidase domain protein BTG_03390 ENOG41062D9 Histidine kinase BTG_03395 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_03440 ENOG41085FC arsR family transcriptional regulator BTG_03445 ENOG4105D6J arsenicaL-resistance protein BTG_03470 ENOG4105DIK (ABC) transporter BTG_03475 ENOG4105CC5 ABC transporter BTG_03480 ENOG4105DSE periplasmic solute binding protein BTG_03485 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BTG_03500 ENOG4107VMI polysaccharide deacetylase BTG_03505 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BTG_03510 ENOG4108TWJ NADH dehydrogenase subunit 5 BTG_03525 ENOG4105CVP deoxyribo-dipyrimidine photolyase BTG_03530 ENOG4108606 TspO/MBR family BTG_03545 ENOG4105F6J Alpha beta hydrolase fold BTG_03570 ENOG41090MY MarR family Transcriptional regulator BTG_03595 ENOG4105CHJ isochorismatase hydrolase BTG_03605 ENOG4105CGH 5'-nucleotidase BTG_03620 ENOG4106A3M Cytochrome p-450 BTG_03665 ENOG4108Q8B Spore germination protein BTG_03670 ENOG4108NHD germination protein BTG_03675 ENOG4105II7 pyrroline-5-carboxylate reductase BTG_03680 ENOG4105CUB amino acid BTG_03685 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BTG_03690 ENOG4105YWU small acid-soluble spore protein BTG_03695 ENOG41075H3 AraC family transcriptional regulator BTG_03720 ENOG4105BZU Histidine kinase BTG_03730 ENOG4108B31 Spore germination protein BTG_03740 ENOG4108IMY Transcriptional regulator BTG_03745 ENOG4105HDK L-asparaginase BTG_03750 ENOG4108IJ0 Aspartate ammonia-lyase BTG_03760 ENOG4105E2A Dehydrogenase BTG_03830 ENOG4105DQ6 Transposase BTG_03845 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BTG_03885 ENOG4105DWD nucleoside recognition domain protein BTG_03900 ENOG4105FDT acyl-CoA dehydrogenase BTG_03910 ENOG4108ZHR arsR family transcriptional regulator BTG_03915 ENOG4106N3A copper homeostasis protein cutc BTG_03925 ENOG4107258 Transcriptional regulator BTG_03930 ENOG4105P4J Allophanate hydrolase, subunit 1 BTG_03960 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BTG_03965 ENOG4107RF6 penicillin-binding protein BTG_03990 ENOG4105BZU Histidine kinase BTG_04005 ENOG4108VJ1 Transcriptional regulator (CarD family BTG_04060 ENOG4108IQI permease BTG_04070 ENOG410635A Membrane BTG_04115 ENOG4108PCN EamA-like transporter family BTG_04130 ENOG4108XET gCN5-related N-acetyltransferase BTG_04155 ENOG4105WEC Molybdate metabolism regulator BTG_04175 ENOG4105FS7 Transcriptional regulator BTG_04180 ENOG4108TVJ Nitroreductase BTG_04200 ENOG4108IBT Inherit from COG: transposase BTG_04245 ENOG4106BHF BTG_04250 ENOG41090AA BTG_04265 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BTG_04305 ENOG4105C8Y Acetylornithine aminotransferase BTG_04330 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BTG_04370 ENOG4105KNA -acetyltransferase BTG_04390 ENOG4105VMP Transcriptional regulator BTG_04400 ENOG4105G6Z alkaline phosphatase BTG_04405 ENOG4107RBI VanW family BTG_04415 ENOG4105ECK Fatty Acid Desaturase BTG_04440 ENOG4107258 Transcriptional regulator BTG_04450 ENOG4105II7 pyrroline-5-carboxylate reductase BTG_04480 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BTG_04500 ENOG41061GT Aldolase BTG_04510 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BTG_04515 ENOG4105DKT Transcriptional regulator BTG_04520 ENOG4105C2J ABC transporter BTG_04525 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BTG_04535 ENOG4105D4B ABC, transporter BTG_04570 ENOG41069ER domain protein BTG_04620 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BTG_04625 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BTG_04650 ENOG41082JN Transcriptional regulator BTG_04655 ENOG4105EYF MMPL domain protein BTG_04660 ENOG4105C5H ABC transporter BTG_04665 ENOG4105E0M Sulfatase BTG_04670 ENOG4108ZCF integral membrane protein BTG_04690 ENOG4107VMI polysaccharide deacetylase BTG_04705 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BTG_04710 ENOG4105C6T cysteine synthase BTG_04715 ENOG4107VC0 DNA alkylation repair enzyme BTG_04750 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BTG_04775 ENOG4105D7T ABC transporter BTG_04780 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BTG_04785 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BTG_04805 ENOG4105C02 permease BTG_04860 ENOG4105CHM Aminotransferase BTG_04895 ENOG41089UC methyltransferase, type 11 BTG_04910 ENOG4107BMA Transglycosylase associated protein BTG_04930 ENOG4106K7D Major facilitator family transporter BTG_04935 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BTG_04995 ENOG4105EPR degv family BTG_05000 ENOG4105DPN Oligoendopeptidase f BTG_05015 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BTG_05030 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_05035 ENOG4105BZU Histidine kinase BTG_05040 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BTG_05045 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BTG_05080 ENOG4107SET aldo keto reductase BTG_05095 ENOG4105DTQ mandelate racemase muconate lactonizing BTG_05110 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BTG_05120 ENOG4107T5V SNARE associated Golgi BTG_05150 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BTG_05160 ENOG41080HI glycine oxidase BTG_05165 ENOG4105CTU Proline racemase BTG_05175 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BTG_05180 ENOG4105C26 Dehydrogenase BTG_05185 ENOG4105BZG amino acid carrier protein BTG_05205 ENOG4108M1A Chitin-binding protein BTG_05260 ENOG4105DQ6 Transposase BTG_05290 ENOG4105C9U ATP-dependent DNA helicase RecQ BTG_05295 ENOG41066HZ AIG2-like family BTG_05300 ENOG4105EEM helicase BTG_05305 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BTG_05330 ENOG4108Z7F N-acetyltransferase BTG_05355 ENOG4105MSB protein, conserved in bacteria BTG_05360 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BTG_05375 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BTG_05395 ENOG4108M1A Chitin-binding protein BTG_05415 ENOG41082BV acetyltransferase BTG_05420 ENOG4105E66 phosphoriboisomerase A BTG_05435 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BTG_05445 ENOG4108IJ7 Glycine betaine BTG_05450 ENOG4107SQ8 Glycine betaine BTG_05480 ENOG4105E1F short-chain dehydrogenase reductase BTG_05495 ENOG4107RUY (E1 component), alpha subunit BTG_05505 ENOG4107QKR Dehydrogenase BTG_05535 ENOG4105IG6 Phage terminase, large subunit BTG_05710 ENOG4105C2M dna polymerase I BTG_05725 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) BTG_05840 ENOG41062ES Transcriptional regulator BTG_05855 ENOG4105E98 transcriptional regulator DeoR family BTG_05875 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BTG_05895 ENOG4107Z3H Transcriptional regulator, TetR family BTG_05900 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BTG_05905 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) BTG_05935 ENOG4105MSI germination protein ypeb BTG_05985 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BTG_05990 ENOG4105FDR Membrane BTG_05995 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BTG_06000 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) BTG_06015 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BTG_06025 ENOG4108IUM Glycogen debranching enzyme BTG_06040 ENOG4105DY8 decarboxylase BTG_06055 ENOG4107WD8 ABC transporter, permease BTG_06075 ENOG4105BZU Histidine kinase BTG_06080 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_06085 ENOG4105U0R haloacid dehalogenase-like hydrolase BTG_06110 ENOG4107VFR oxidoreductase BTG_06130 ENOG41087PP glycosyltransferase MGT family BTG_06165 ENOG4105PKS Excinuclease abc c subunit domain protein BTG_06175 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BTG_06190 ENOG4108YYS metal-dependent hydrolase (By similarity) BTG_06200 ENOG4105KWG Pfam:DUF1696 BTG_06205 ENOG4108NRW Phospholipase, patatin family BTG_06225 ENOG4108XI2 Domain of unknown function (DUF1963) BTG_06255 ENOG4105DQ6 Transposase BTG_06265 ENOG4108Z4K mutator MutT protein BTG_06270 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BTG_06290 ENOG4105FCD Major Facilitator BTG_06315 ENOG4105EGD dinuclear metal center protein, YbgI family BTG_06335 ENOG4107Y9U Membrane BTG_06365 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BTG_06435 ENOG4105CJN penicillin-binding protein BTG_06440 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BTG_06445 ENOG4105CB2 alcohol dehydrogenase BTG_06540 ENOG4108HGU Histidine kinase BTG_06555 ENOG4108JJB ABC transporter BTG_06580 ENOG4107RF6 penicillin-binding protein BTG_06585 ENOG4105BZU Histidine kinase BTG_06590 ENOG410667J hydrolase BTG_06675 ENOG4105ETU transcriptional activator (TenA BTG_06680 ENOG4105CPF Cell wall formation (By similarity) BTG_06690 ENOG4105D6E homoserine dehydrogenase BTG_06730 ENOG4105CPC Aldo Keto reductase BTG_06735 ENOG4106NZI LysR family Transcriptional regulator BTG_06760 ENOG4105DK7 lysyl-tRNA synthetase BTG_06765 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BTG_06775 ENOG4108V4B ThiJ pfpI BTG_06785 ENOG410900G Protein of unknown function (DUF421) BTG_06870 ENOG4105KVH Transcriptional regulator BTG_06875 ENOG4105CHR reductase BTG_06885 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BTG_06915 ENOG41075H3 AraC family transcriptional regulator BTG_06935 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BTG_06945 ENOG4105T9C HD domain BTG_06960 ENOG4105DZ1 carboxypeptidase BTG_06975 ENOG4105DBI uridine monophosphokinase BTG_06990 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BTG_06995 ENOG4107QX3 carboxylase BTG_07000 ENOG4105E39 Enoyl-CoA hydratase BTG_07005 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BTG_07010 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BTG_07015 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BTG_07020 ENOG4105C1G acyl-Coa dehydrogenase BTG_07035 ENOG4107Z3H Transcriptional regulator, TetR family BTG_07075 ENOG4105XSJ toxin secretion phage lysis holin BTG_07140 ENOG4108N9J Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BTG_07220 ENOG4107RHI Cytosine-specific methyltransferase BTG_07270 ENOG4105KRN Transcriptional regulator, abrb family BTG_07300 ENOG41067QW Transcriptional regulator BTG_07315 ENOG4105VTR Integrase BTG_07325 ENOG4105CJ1 ABC, transporter BTG_07335 ENOG4105DIN metallophosphoesterase BTG_07345 ENOG4107RF6 penicillin-binding protein BTG_07350 ENOG4107RF6 penicillin-binding protein BTG_07370 ENOG4107RVG penicillin-binding protein BTG_07380 ENOG4105CJW magnesium transporter BTG_07405 ENOG4108NHD germination protein BTG_07410 ENOG4108NHD germination protein BTG_07415 ENOG4108NHD germination protein BTG_07420 ENOG4105F6S Spore photoproduct lyase BTG_07440 ENOG4105C44 Serine transporter BTG_07445 ENOG4105EJQ L-serine dehydratase BTG_07510 ENOG4107VMI polysaccharide deacetylase BTG_07525 ENOG4108IMY Transcriptional regulator BTG_07580 ENOG4108SC4 )-transporter BTG_07585 ENOG4105IIU Aminopeptidase BTG_07595 ENOG4105FJR Lmbe family BTG_07610 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BTG_07615 ENOG4108IAJ Nad-dependent epimerase dehydratase BTG_07620 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BTG_07625 ENOG4107QQG Dehydrogenase BTG_07630 ENOG4108W0I acetyltransferase BTG_07695 ENOG4105CHR reductase BTG_07705 ENOG4105W8Z 4'-phosphopantetheinyl transferase BTG_07755 ENOG4105EJ9 Membrane BTG_07765 ENOG4105KRN Transcriptional regulator, abrb family BTG_07790 ENOG4105CIN aminoacyl-histidine dipeptidase BTG_07815 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BTG_07820 ENOG4105K56 Transcriptional regulator BTG_07835 ENOG4108I0C methyltransferase BTG_07845 ENOG41088CC tellurite resistance protein tehB BTG_07850 ENOG4105C1J atp-dependent rna helicase BTG_07860 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BTG_07875 ENOG4108INS Transcriptional regulator BTG_07880 ENOG4105C7B Threonine dehydratase BTG_07885 ENOG4107STF Involved in phosphonate degradation (By similarity) BTG_07890 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BTG_07895 ENOG4105RD7 BadF BadG BcrA BcrD BTG_07920 ENOG4105F32 YngK protein BTG_07945 ENOG4108KPJ rna polymerase sigma factor BTG_07950 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BTG_07985 ENOG4108JCI Transcriptional regulator BTG_08015 ENOG4105BZ1 (ABC) transporter BTG_08020 ENOG4105BZ1 (ABC) transporter BTG_08035 ENOG4108RPX mosc domain containing protein BTG_08040 ENOG4105DND Transcriptional regulator BTG_08050 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BTG_08055 ENOG4107V2S Transcriptional regulator BTG_08060 ENOG4105DQ6 Transposase BTG_08095 ENOG41068WN BTG_08105 ENOG4105C1Q protoporphyrinogen oxidase BTG_08130 ENOG4105WCN acetyltransferase BTG_08155 ENOG4105EYF MMPL domain protein BTG_08165 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BTG_08180 ENOG4108Y4K DNA-binding transcriptional activator BTG_08190 ENOG41081I9 integral membrane protein BTG_08225 ENOG4105C19 ABC transporter BTG_08230 ENOG4105C22 threonyL-tRNA synthetase BTG_08235 ENOG4105FE9 pseudouridine synthase BTG_08255 ENOG4105BZG amino acid carrier protein BTG_08275 ENOG4105K70 DNA-binding protein BTG_08290 ENOG4105C0R drug resistance transporter emrb qaca subfamily BTG_08295 ENOG4105WQT MbtH domain protein BTG_08300 ENOG4105CEY Amp-dependent synthetase and ligase BTG_08305 ENOG4105WQI isochorismatase BTG_08310 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BTG_08315 ENOG4105E4F Isochorismate synthase BTG_08320 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BTG_08325 ENOG4105FCD Major Facilitator BTG_08345 ENOG4105EYH Exonuclease BTG_08350 ENOG4107RFY SbcCD D subunit BTG_08365 ENOG4105E39 Enoyl-CoA hydratase BTG_08370 ENOG4105N14 lysine exporter protein LysE YggA BTG_08380 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BTG_08385 ENOG4105C1G acyl-Coa dehydrogenase BTG_08395 ENOG4105CR4 methylisocitrate lyase BTG_08400 ENOG4105DXD 2-methylcitrate dehydratase BTG_08410 ENOG4105W8X HesB YadR YfhF-family protein BTG_08415 ENOG4105CZM Major Facilitator BTG_08425 ENOG4105BZ4 penicillin-binding protein BTG_08485 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BTG_08550 ENOG4105KNA -acetyltransferase BTG_08555 ENOG4105SZ6 Thioredoxin BTG_08570 ENOG410841Q phosphoesterase PA-phosphatase related protein BTG_08620 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BTG_08625 ENOG4108JUB Transcriptional regulator BTG_08630 ENOG4108TSC N-acetyltransferase BTG_08635 ENOG4107S4Y M20 DapE family protein YgeY BTG_08650 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BTG_08675 ENOG4105C37 (CBS) domain BTG_08710 ENOG4105E90 ABC transporter BTG_08715 ENOG4108IJ8 ABC transporter BTG_08740 ENOG4108YV3 Protein of unknown function (DUF2711) BTG_08750 ENOG4105C6Z Gluconate BTG_08755 ENOG4105CMG Carbohydrate kinase BTG_08780 ENOG4107ZY0 Phenazine biosynthesis-like protein BTG_08785 ENOG4106KNT transcriptional regulator BTG_08790 ENOG4105WH1 Two component transcriptional regulator luxr family BTG_08795 ENOG4105BZU Histidine kinase BTG_08800 ENOG4105D8X mechanosensitive ion channel BTG_08835 ENOG4105F0I Aminotransferase BTG_08840 ENOG4108MES Periplasmic binding protein BTG_08845 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BTG_08860 ENOG4105CAQ asparagine synthetase BTG_08865 ENOG4107Y70 Heat shock protein BTG_08870 ENOG4108KF3 Electron transport protein SCO1 SenC BTG_08885 ENOG4108RCR degv family BTG_08895 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BTG_08905 ENOG4108UT2 hemolysin iii BTG_08910 ENOG4105E9Q Acyl-transferase BTG_08920 ENOG4107RVG penicillin-binding protein BTG_08950 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BTG_08980 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BTG_08985 ENOG4105VMP Transcriptional regulator BTG_08995 ENOG4105KD7 acetyltransferase BTG_09015 ENOG4105CY2 Citrate transporter BTG_09020 ENOG4107XGZ Hydrolase BTG_09035 ENOG4108EF6 Proline imino-peptidase BTG_09040 ENOG4105C8J )-transporter BTG_09045 ENOG4105C5S asparaginyl-tRNA synthetase BTG_09060 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BTG_09080 ENOG4105C75 arginyL-tRNA synthetase BTG_09085 ENOG4107YX5 Pfam:DUF548 BTG_09115 ENOG4108UUM single-stranded DNA-binding protein BTG_09130 ENOG4105C5H ABC transporter BTG_09165 ENOG4105MCT stage V sporulation protein S BTG_09200 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BTG_09205 ENOG4108IFG nitrite reductase, (NAD(P)H) BTG_09210 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BTG_09215 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BTG_09220 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BTG_09225 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BTG_09255 ENOG4108ZAF Molybdopterin BTG_09260 ENOG4105CVM Molybdenum cofactor synthesis domain protein BTG_09265 ENOG4105D06 uba thif-type nad fad binding protein BTG_09270 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BTG_09275 ENOG4107V6Q Cyclic nucleotide-binding domain BTG_09285 ENOG4105R3A Nitrate reductase BTG_09290 ENOG4108IUE nitrate reductase beta subunit BTG_09300 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BTG_09315 ENOG4108V06 Glutathione peroxidase BTG_09325 ENOG4105CNW domain protein BTG_09335 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BTG_09345 ENOG4105EMN RNA polymerase sigma factor BTG_09350 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BTG_09360 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BTG_09365 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BTG_09385 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BTG_09410 ENOG4105KBJ sporulation protein ytfj BTG_09505 ENOG4108MGT Required for secretion of EsxA and EsxB BTG_09510 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) BTG_09520 ENOG4106PAW secretion accessory protein EsaA YueB BTG_09540 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BTG_09570 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BTG_09575 ENOG4108JYZ YitT family BTG_09580 ENOG41087PP glycosyltransferase MGT family BTG_09595 ENOG4107RBS Methyltransferase BTG_09600 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BTG_09610 ENOG4105D94 Major Facilitator Superfamily BTG_09615 ENOG41082F9 transcriptional regulator BTG_09620 ENOG4108X4Q Hydrolase BTG_09630 ENOG4108ZRV stage ii sporulation protein p BTG_09650 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BTG_09660 ENOG4108VXD carboxy-peptidase BTG_09670 ENOG4108ZRV stage ii sporulation protein p BTG_09685 ENOG4108Z7R Chaperone CsaA BTG_09715 ENOG4105C37 (CBS) domain BTG_09720 ENOG4105SXS Protein of unknown function (DUF456) BTG_09740 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BTG_09750 ENOG4108S4H thioesterase Superfamily protein BTG_09760 ENOG4108PJD permease BTG_09775 ENOG4107T5V SNARE associated Golgi BTG_09790 ENOG4105CVJ phosphoglycerate mutase BTG_09815 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BTG_09825 ENOG4105K4T epimerase BTG_09835 ENOG4105DSE periplasmic solute binding protein BTG_09845 ENOG4105CKI cobalamin synthesis protein BTG_09850 ENOG4107QM2 Aldo Keto reductase BTG_09855 ENOG4105DQ6 Transposase BTG_09865 ENOG4105VMI -acetyltransferase BTG_09880 ENOG4105DEN Luciferase family BTG_09895 ENOG4108WPJ Ferritin-like domain BTG_09900 ENOG4108K88 Membrane BTG_09915 ENOG4105C8Q Methyl-accepting chemotaxis BTG_09940 ENOG4107XZQ multidrug resistance protein BTG_09945 ENOG4105CPC Aldo Keto reductase BTG_09950 ENOG4105YVS arsR family transcriptional regulator BTG_09960 ENOG4105KRN Transcriptional regulator, abrb family BTG_10010 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BTG_10015 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BTG_10025 ENOG4105YWU small acid-soluble spore protein BTG_10030 ENOG4108WBH protein TIM barrel BTG_10045 ENOG4105CEY Amp-dependent synthetase and ligase BTG_10050 ENOG4105DUU IucA IucC family protein BTG_10060 ENOG4105VRR gCN5-related N-acetyltransferase BTG_10065 ENOG4105KT7 mgtC SapB transporter BTG_10080 ENOG4108KGH TRANSCRIPTIONal BTG_10105 ENOG4105D6E homoserine dehydrogenase BTG_10125 ENOG4108ZJ4 polysaccharide deacetylase BTG_10130 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BTG_10150 ENOG4105BZU Histidine kinase BTG_10155 ENOG4105EFI regulatoR BTG_10160 ENOG4105BZ1 (ABC) transporter BTG_10215 ENOG4108UT6 Transferase hexapeptide repeat containing protein BTG_10225 ENOG4105K64 Glycosyl transferase, family 2 BTG_10235 ENOG4108JJ8 (ABC) transporter BTG_10240 ENOG4108JJ9 ABC, transporter BTG_10245 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BTG_10250 ENOG4105C4M (Ubiquinol oxidase) subunit I BTG_10275 ENOG4105MDS 4-oxalocrotonate tautomerase BTG_10285 ENOG4105EGI Transcriptional regulator BTG_10295 ENOG4105C32 Amino acid ABC transporter (Permease) BTG_10300 ENOG4108IV0 ABC, transporter BTG_10305 ENOG4105C0Z ABC transporter BTG_10315 ENOG4105CKI cobalamin synthesis protein BTG_10325 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BTG_10330 ENOG4106F5Q Membrane BTG_10335 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BTG_10410 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BTG_10420 ENOG41085W3 Transposase BTG_10560 ENOG4105KRN Transcriptional regulator, abrb family BTG_10655 ENOG4105C2M dna polymerase I BTG_10730 ENOG41085W3 Transposase BTG_10755 ENOG4105DQ6 Transposase BTG_10780 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BTG_10790 ENOG4108TVJ Nitroreductase BTG_10795 ENOG4107ZXU DSBA oxidoreductase BTG_10800 ENOG4108Z40 Transcriptional regulator BTG_10805 ENOG4105GZI Transcriptional regulator BTG_10810 ENOG4107RT3 EamA-like transporter family BTG_10815 ENOG4105KTB nuclear export factor GLE1 BTG_10820 ENOG4108T5E Copper resistance protein BTG_10875 ENOG4105E1K spore germination protein BTG_10890 ENOG4105E1K spore germination protein BTG_10940 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_10955 ENOG4105C7F AcnD-accessory protein PrpF BTG_10965 ENOG4108TGR phosphatase BTG_11020 ENOG4105D7V transposase BTG_11040 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BTG_11050 ENOG4105CNI cell division protein FtsW BTG_11055 ENOG4105CNI cell division protein FtsW BTG_11060 ENOG4105CJW magnesium transporter BTG_11065 ENOG4108KGH TRANSCRIPTIONal BTG_11075 ENOG4107TVC Glycosyl transferase, family 2 BTG_11085 ENOG4105E1K spore germination protein BTG_11100 ENOG4105KT7 mgtC SapB transporter BTG_11115 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BTG_11140 ENOG4108IMY Transcriptional regulator BTG_11175 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BTG_11185 ENOG4105C0H protease BTG_11220 ENOG4105CNI cell division protein FtsW BTG_11250 ENOG4107VMI polysaccharide deacetylase BTG_11255 ENOG4105JVQ RNA Polymerase BTG_11300 ENOG4107R16 Multicopper oxidase BTG_11310 ENOG4107RAQ aminopeptidase BTG_11330 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BTG_11335 ENOG4105D9N nucleoside BTG_11345 ENOG4107RHR regulatoR BTG_11360 ENOG4105K8R UPF0145 protein BTG_11365 ENOG410849A acetyltransferase, (GNAT) family BTG_11400 ENOG4105C0X amino acid BTG_11410 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BTG_11425 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BTG_11445 ENOG41068WN BTG_11470 ENOG4105CYC Transferase BTG_11475 ENOG4105DY9 regulatoR BTG_11490 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BTG_11495 ENOG4105C6X Major Facilitator BTG_11520 ENOG4105C7B Threonine dehydratase BTG_11530 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BTG_11540 ENOG4105C7K acetolactate synthase BTG_11545 ENOG4105CM2 brancheD-chain amino acid aminotransferase BTG_11550 ENOG4105CHR reductase BTG_11555 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BTG_11580 ENOG4105H67 Protein of unknown function (DUF421) BTG_11585 ENOG4105X5K response regulator receiver protein BTG_11595 ENOG4105C8J )-transporter BTG_11615 ENOG4105C6T cysteine synthase BTG_11620 ENOG4105EU0 Major facilitator Superfamily BTG_11625 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BTG_11635 ENOG4105DXI Major Facilitator superfamily BTG_11645 ENOG4105U3E Transcriptional regulator BTG_11650 ENOG4105CSR polyphosphate kinase 2 BTG_11665 ENOG4105E09 nadh pyrophosphatase BTG_11670 ENOG4105FVX BTG_11730 ENOG4105C6K Malic enzyme BTG_11735 ENOG4108IJ0 Aspartate ammonia-lyase BTG_11745 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BTG_11765 ENOG4105CJ1 ABC, transporter BTG_11800 ENOG4106BRA Membrane BTG_11815 ENOG4105IYK transposase BTG_11870 ENOG4105C2M dna polymerase I BTG_11895 ENOG4105K63 Thioredoxin BTG_11930 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_12100 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BTG_12120 ENOG4105EC3 peptidase S51, dipeptidase E BTG_12125 ENOG4107QJQ Mate efflux family protein BTG_12150 ENOG4105C9Q fumarate hydratase class II BTG_12170 ENOG4105DFD Na H antiporter BTG_12185 ENOG4108PJD permease BTG_12190 ENOG4105CKI cobalamin synthesis protein BTG_12205 ENOG4105PGM cation diffusion facilitator family transporter BTG_12225 ENOG4105CAQ asparagine synthetase BTG_12235 ENOG4105K56 Transcriptional regulator BTG_12245 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BTG_12255 ENOG4105CVJ phosphoglycerate mutase BTG_12295 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BTG_12305 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BTG_12310 ENOG4105DUM transcriptional regulator, lysR family BTG_12335 ENOG4107QZ7 Cellulose synthase catalytic subunit BTG_12340 ENOG4105KAC Antibiotic biosynthesis monooxygenase BTG_12370 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BTG_12375 ENOG4105CPU Monooxygenase BTG_12380 ENOG4105KTQ flagellar basal-body rod protein BTG_12385 ENOG4105FZW flagellar biosynthesis regulator FlhF BTG_12390 ENOG4105D7B Flagellar biosynthesis protein flha BTG_12395 ENOG4105D00 flagellar biosynthetic protein flhB BTG_12405 ENOG4105VS8 Flagellar biosynthetic protein fliq BTG_12410 ENOG4105CN7 Flagellar biosynthetic protein FliP BTG_12420 ENOG4105DD5 Flagellar motor switch protein BTG_12425 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BTG_12435 ENOG4105E4C Lytic transglycosylase catalytic BTG_12440 ENOG4105I03 Flagellin BTG_12445 ENOG4105I03 Flagellin BTG_12455 ENOG4107R88 Chemotaxis protein (CheV) BTG_12470 ENOG4105BZE flagellar hook protein, FlgE BTG_12500 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BTG_12505 ENOG4107U2N Flagellar M-ring protein BTG_12510 ENOG41075Z6 flagellar hook-basal body complex protein fliE BTG_12515 ENOG4108ZC9 flagellar basal-body rod protein flgc BTG_12520 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BTG_12535 ENOG4105DTS flagellar hook-associated BTG_12540 ENOG4105DTJ flagellar hook-associated protein BTG_12545 ENOG4105E1Q flagellar hook-associated protein BTG_12565 ENOG4105BZU Histidine kinase BTG_12580 ENOG4105DD5 Flagellar motor switch protein BTG_12585 ENOG4105CBS Chea signal transduction histidine kinase BTG_12590 ENOG4107YTP response regulator receiver protein BTG_12595 ENOG4105ER2 Ompa motb domain protein BTG_12600 ENOG4107R0U MotA TolQ exbB proton channel BTG_12610 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BTG_12645 ENOG41080C8 DUF218 domain BTG_12650 ENOG4105H67 Protein of unknown function (DUF421) BTG_12660 ENOG4108Z5V transcriptional regulator, merr family BTG_12665 ENOG4105CN5 Metallo-Beta-Lactamase BTG_12670 ENOG4107RWR Sodium hydrogen exchanger BTG_12680 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BTG_12745 ENOG41081VK Ribonuclease BTG_12765 ENOG4108SZE gCN5-related N-acetyltransferase BTG_12780 ENOG4105CPK Glycosyl transferase (Group 1 BTG_12810 ENOG4105HTX biosynthesis protein BTG_12840 ENOG4106032 Glutathionylspermidine synthase BTG_12860 ENOG4105KHC sulfurtransferase BTG_12870 ENOG4108W0I acetyltransferase BTG_12880 ENOG410890F Dynamin family BTG_12890 ENOG4105DHF Membrane BTG_12895 ENOG4105C2W permease BTG_12905 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BTG_12925 ENOG4105CTD carboxy-peptidase BTG_12930 ENOG4105DVT helicase BTG_12940 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BTG_12995 ENOG4105BZ4 penicillin-binding protein BTG_13005 ENOG4105CSM endonuclease III BTG_13025 ENOG4105YAC BTG_13030 ENOG4105DVT helicase BTG_13065 ENOG4105CPK Glycosyl transferase (Group 1 BTG_13070 ENOG4105FJR Lmbe family BTG_13085 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BTG_13090 ENOG4108JYZ YitT family BTG_13125 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BTG_13130 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BTG_13145 ENOG41068YB TPR repeat-containing protein BTG_13160 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BTG_13165 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BTG_13170 ENOG4105EAH synthase BTG_13180 ENOG4105XXQ heptaprenyl diphosphate synthase component I BTG_13195 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BTG_13225 ENOG41065D1 BTG_13230 ENOG4105S2F BTG_13265 ENOG4107RB3 L-asparaginase BTG_13270 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BTG_13295 ENOG4108S6Z Negative regulator of genetic competence BTG_13300 ENOG4108XDN Transcriptional regulator BTG_13305 ENOG4107RGJ metallophosphoesterase BTG_13315 ENOG4105I7S Abortive infection protein BTG_13320 ENOG4105C9U ATP-dependent DNA helicase RecQ BTG_13335 ENOG4108SAX Membrane BTG_13350 ENOG4108WBT adenosyltransferase BTG_13355 ENOG4105BZU Histidine kinase BTG_13360 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_13365 ENOG4105CRE cytochrome C BTG_13370 ENOG4107TWT Cytochrome c biogenesis protein BTG_13375 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BTG_13380 ENOG4105FE9 pseudouridine synthase BTG_13390 ENOG4108JIC nucleoside recognition domain protein BTG_13395 ENOG4105DZ1 carboxypeptidase BTG_13400 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BTG_13430 ENOG4105BZU Histidine kinase BTG_13450 ENOG4105I3N Conserved Protein BTG_13455 ENOG4105BZU Histidine kinase BTG_13470 ENOG4105BZ4 penicillin-binding protein BTG_13475 ENOG4107GRR phosphate transport regulator BTG_13480 ENOG4105CJ3 phosphate transporter BTG_13500 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BTG_13525 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BTG_13545 ENOG4105WH1 Two component transcriptional regulator luxr family BTG_13550 ENOG4105ENE Histidine kinase BTG_13570 ENOG4105DFD Na H antiporter BTG_13595 ENOG4105C8J )-transporter BTG_13600 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BTG_13605 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BTG_13610 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BTG_13620 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BTG_13625 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BTG_13645 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BTG_13655 ENOG4105E0M Sulfatase BTG_13660 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BTG_13675 ENOG4107RVV histidinol phosphate phosphatase, hisj family BTG_13710 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BTG_13745 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BTG_13750 ENOG4108ZP8 Acetolactate synthase small subunit BTG_13755 ENOG4105C7K acetolactate synthase BTG_13760 ENOG4105CM2 brancheD-chain amino acid aminotransferase BTG_13780 ENOG4105KBJ sporulation protein ytfj BTG_13785 ENOG41063Y9 BTG_13790 ENOG4105CZN Potassium uptake protein BTG_13825 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BTG_13865 ENOG4105NQC Flavodoxin BTG_13890 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BTG_13900 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BTG_13905 ENOG4105EA8 2-Nitropropane dioxygenase BTG_13910 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BTG_13950 ENOG4105CJ1 ABC, transporter BTG_13960 ENOG4105CZV ABC transporter BTG_13965 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BTG_13970 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BTG_13975 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BTG_13980 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BTG_14020 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BTG_14025 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BTG_14035 ENOG4105BZU Histidine kinase BTG_14050 ENOG4106DF1 BTG_14060 ENOG41090MY MarR family Transcriptional regulator BTG_14065 ENOG4105BZU Histidine kinase BTG_14075 ENOG4105PXI polysaccharide deacetylase BTG_14085 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BTG_14100 ENOG4105E98 transcriptional regulator DeoR family BTG_14120 ENOG4107RCV ABC transporter, permease BTG_14125 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BTG_14130 ENOG4105C4Y ABC transporter BTG_14160 ENOG4105CHR reductase BTG_14180 ENOG4108Z7G MaoC domain protein dehydratase BTG_14185 ENOG410681C small acid-soluble spore protein BTG_14190 ENOG4105CZN Potassium uptake protein BTG_14195 ENOG4107TS3 membrane protein, TerC BTG_14200 ENOG4108QTI )-transporter BTG_14210 ENOG4106A3R peptidase BTG_14230 ENOG4105JXH GntR family transcriptional regulator BTG_14235 ENOG4105BZU Histidine kinase BTG_14240 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_14255 ENOG4105CQB FAD linked oxidase domain protein BTG_14260 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BTG_14265 ENOG4105K4I Scp-like extracellular BTG_14275 ENOG4108YBP pseudouridine synthase BTG_14285 ENOG4105EYF MMPL domain protein BTG_14290 ENOG410841Q phosphoesterase PA-phosphatase related protein BTG_14295 ENOG4107RUE extracellular solute-binding protein family 1 BTG_14300 ENOG4105D38 putrescine abc transporter BTG_14305 ENOG4105F38 ABC transporter, permease BTG_14310 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BTG_14315 ENOG4105C26 Dehydrogenase BTG_14355 ENOG4105VFR signal peptidase BTG_14360 ENOG4105DZ1 carboxypeptidase BTG_14370 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BTG_14385 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BTG_14470 ENOG4105VZ8 Transcriptional regulator BTG_14480 ENOG4105C7S Dehydrogenase BTG_14575 ENOG4105DDQ anthranilate synthase BTG_14580 ENOG4105CRQ synthase (Component I) BTG_14590 ENOG4105CK7 Sodium proline symporter BTG_14665 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BTG_14675 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BTG_14680 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BTG_14700 ENOG4107TVC Glycosyl transferase, family 2 BTG_14720 ENOG4105K64 Glycosyl transferase, family 2 BTG_14740 ENOG4105EMS pseudouridine synthase BTG_14745 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BTG_14760 ENOG4105MIX Adenylate cyclase BTG_14765 ENOG4108Z18 K06886 hemoglobin BTG_14780 ENOG4105DPN Oligoendopeptidase f BTG_14790 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BTG_14800 ENOG4108ZCF integral membrane protein BTG_14820 ENOG4105UQX Mate efflux family protein BTG_14825 ENOG4108JQ7 (ABC) transporter BTG_14840 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BTG_14845 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BTG_14860 ENOG4105C31 Tryptophanyl-tRNA synthetase BTG_14880 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BTG_14885 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BTG_14910 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BTG_14920 ENOG4108KP7 hydrolase BTG_14930 ENOG41073B9 BTG_14935 ENOG4107AYK membrAne BTG_14945 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BTG_14950 ENOG4105QNR S1 RNA binding domain protein BTG_14970 ENOG4105BZU Histidine kinase BTG_14975 ENOG4105CH6 catalase BTG_14980 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BTG_14985 ENOG4105CAQ asparagine synthetase BTG_14995 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BTG_15020 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BTG_15250 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BTG_15265 ENOG4105CAQ asparagine synthetase BTG_15280 ENOG4105C8Y Acetylornithine aminotransferase BTG_15285 ENOG4105ERH Fumarylacetoacetate hydrolase BTG_15325 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BTG_15330 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation BTG_15350 ENOG4105XVF Competence transcription factor BTG_15365 ENOG4105VEQ Cold shock protein BTG_15385 ENOG4107QP3 malate synthase g BTG_15395 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) BTG_15405 ENOG4105C8Q Methyl-accepting chemotaxis BTG_15410 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BTG_15435 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BTG_15455 ENOG41086D8 Transcriptional regulator BTG_15460 ENOG4108AEY RNA polymerase sigma factor BTG_15480 ENOG4107RN3 metallophosphoesterase BTG_15485 ENOG4105ENX hydrolase BTG_15490 ENOG4105ST3 Transcriptional regulator BTG_15510 ENOG4105CEY Amp-dependent synthetase and ligase BTG_15520 ENOG4105DF9 Lipoate-protein, ligase BTG_15525 ENOG4108RQ5 Beta-lactamase domain-containing protein BTG_15530 ENOG4106AXD BTG_15560 ENOG4105ECB domain protein BTG_15595 ENOG4105C1Q protoporphyrinogen oxidase BTG_15600 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BTG_15610 ENOG4105BZ4 penicillin-binding protein BTG_15615 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BTG_15620 ENOG4105CKV Membrane BTG_15625 ENOG410905X membrane-flanked domain protein BTG_15670 ENOG4105CKV Membrane BTG_15675 ENOG410905X membrane-flanked domain protein BTG_15710 ENOG4105K59 histidine triad (HIT) protein BTG_15735 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BTG_15740 ENOG4105EEM helicase BTG_15755 ENOG4105EMN RNA polymerase sigma factor BTG_15775 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BTG_15790 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BTG_15795 ENOG41067QW Transcriptional regulator BTG_15800 ENOG4105F0F Oxalate decarboxylase BTG_15825 ENOG4108MUZ hydrolase BTG_15835 ENOG4107JM4 Tetratricopeptide repeat BTG_15850 ENOG410829K Lysine exporter protein (Lyse ygga) BTG_15865 ENOG4106D4I domain protein BTG_15870 ENOG4107VRP DNA repair exonuclease BTG_15890 ENOG4107QHE Choloylglycine hydrolase BTG_15905 ENOG4105D7V transposase BTG_15945 ENOG4105BZU Histidine kinase BTG_15950 ENOG4105BZU Histidine kinase BTG_15960 ENOG4108MJI response regulator BTG_15970 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_15980 ENOG4105WN5 stage II sporulation protein BTG_16080 ENOG410847I Transcriptional regulator, BadM Rrf2 family BTG_16090 ENOG4105CMT Dihydroxyacetone kinase BTG_16100 ENOG4105CMT Dihydroxyacetone kinase BTG_16110 ENOG4105WAB arsR family transcriptional regulator BTG_16115 ENOG4105F27 Major Facilitator BTG_16125 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BTG_16140 ENOG4108IG5 Transcriptional regulator BTG_16145 ENOG4107P5I polyketide synthase BTG_16290 ENOG4105C0R drug resistance transporter emrb qaca subfamily BTG_16320 ENOG4105CDU Replicative dna helicase BTG_16330 ENOG4105DVF Cytosine-specific methyltransferase BTG_16345 ENOG4105EB3 Histidine kinase BTG_16365 ENOG4105C4R Atp-dependent dna helicase BTG_16370 ENOG4105C4R Atp-dependent dna helicase BTG_16380 ENOG4105DZR Type I site-specific deoxyribonuclease BTG_16390 ENOG4105CVR type I restriction-modification system BTG_16430 ENOG4108MRH transcriptional regulatory protein BTG_16440 ENOG4105CSH Transporter BTG_16495 ENOG4108IBT Inherit from COG: transposase BTG_16605 ENOG4108IBT Inherit from COG: transposase BTG_16625 ENOG4105DQ6 Transposase BTG_16665 ENOG4107SFI Major Facilitator superfamily BTG_16670 ENOG4105D06 uba thif-type nad fad binding protein BTG_16685 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase BTG_16745 ENOG4108JQ7 (ABC) transporter BTG_16755 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BTG_16770 ENOG4105CIF Ornithine Cyclodeaminase BTG_16775 ENOG4105CTU Proline racemase BTG_16795 ENOG4105DER m42 family BTG_16815 ENOG4105CGU Enoyl-CoA hydratase BTG_16840 ENOG4105CHH sulfate transporter BTG_16855 ENOG4105CEY Amp-dependent synthetase and ligase BTG_16860 ENOG4105D4P Coproporphyrinogen iii oxidase BTG_16865 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BTG_16885 ENOG4107FQX Alpha-acetolactate decarboxylase BTG_16895 ENOG4105BZ1 (ABC) transporter BTG_16900 ENOG41085W3 Transposase BTG_16905 ENOG4105CJA serine threonine protein kinase BTG_16915 ENOG4105K7K Transcriptional regulator BTG_16945 ENOG410839P BTG_16960 ENOG4105CDA abc transporter atp-binding protein BTG_16965 ENOG4105DRP amino acid AbC transporter BTG_16975 ENOG4105BZ1 (ABC) transporter BTG_16980 ENOG4105BZ1 (ABC) transporter BTG_16985 ENOG4105C26 Dehydrogenase BTG_16990 ENOG4105D5Q Arginine ornithine antiporter BTG_17000 ENOG4105CH6 catalase BTG_17005 ENOG4107RKG DJ-1/PfpI family BTG_17025 ENOG4105KPY Small multidrug resistance protein BTG_17035 ENOG4108IXY short-chain dehydrogenase reductase BTG_17040 ENOG4105CH7 arginosuccinase BTG_17045 ENOG4108YXU transcriptional regulator AsnC family BTG_17085 ENOG4106KNT transcriptional regulator BTG_17095 ENOG4107RWR Sodium hydrogen exchanger BTG_17100 ENOG4105CUB amino acid BTG_17130 ENOG4107T5V SNARE associated Golgi BTG_17165 ENOG4105WEF catalase BTG_17195 ENOG4105C19 ABC transporter BTG_17200 ENOG4107RBB ABC transporter, permease BTG_17205 ENOG41069ER domain protein BTG_17230 ENOG4105VZJ PTS System BTG_17235 ENOG4105VCP PTS System BTG_17240 ENOG4105EMD TRANSCRIPTIONal BTG_17265 ENOG4108KGH TRANSCRIPTIONal BTG_17275 ENOG41087NI Sulfite exporter TauE/SafE BTG_17280 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BTG_17290 ENOG4105VFE sira family BTG_17295 ENOG4105VFE sira family BTG_17300 ENOG4107TPS domain protein BTG_17305 ENOG4105VFE sira family BTG_17310 ENOG4105XTG Pfam:DUF156 BTG_17320 ENOG4108TCS Glutamyl endopeptidase BTG_17335 ENOG4105ED1 spovr family BTG_17340 ENOG4107Y03 Nitroreductase BTG_17360 ENOG4108B31 Spore germination protein BTG_17380 ENOG4105K63 Thioredoxin BTG_17395 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BTG_17405 ENOG4105C7N Xanthine uracil vitamin C permease BTG_17420 ENOG4108INS Transcriptional regulator BTG_17465 ENOG4105DWF phosphomethylpyrimidine kinase BTG_17470 ENOG4105D06 uba thif-type nad fad binding protein BTG_17485 ENOG41080HI glycine oxidase BTG_17490 ENOG4108VEU Thiamine monophosphate synthase BTG_17500 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BTG_17510 ENOG4105ETU transcriptional activator (TenA BTG_17530 ENOG41080XQ Signal transduction protein with cbs domains BTG_17550 ENOG4105E2Z phosphate ABC transporter (Permease BTG_17555 ENOG4105C8U phosphate abc transporter BTG_17560 ENOG4105CVA phosphate BTG_17565 ENOG4105CE1 Ferrous iron transport protein b BTG_17570 ENOG4105CE1 Ferrous iron transport protein b BTG_17575 ENOG4105CE1 Ferrous iron transport protein b BTG_17585 ENOG4108NHD germination protein BTG_17590 ENOG4108NHD germination protein BTG_17605 ENOG4105E1V na solute symporter BTG_17610 ENOG4106CAD Protein of unknown function (DUF3311) BTG_17630 ENOG4105E2S oxidase) subunit II BTG_17635 ENOG4105BZ9 Cytochrome C oxidase, subunit I BTG_17660 ENOG4105MA6 gCN5-related N-acetyltransferase BTG_17675 ENOG4105C7N Xanthine uracil vitamin C permease BTG_17680 ENOG4105C85 amino acid BTG_17705 ENOG4105DUX Transporter BTG_17720 ENOG4107D63 BTG_17725 ENOG4105VZ8 Transcriptional regulator BTG_17730 ENOG41069ER domain protein BTG_17735 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BTG_17740 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BTG_17770 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) BTG_17810 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BTG_17815 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BTG_17820 ENOG4105CNN ABC, transporter BTG_17825 ENOG4105C2J ABC transporter BTG_17835 ENOG4108RVA ribokinase BTG_17840 ENOG4105ETE Transcriptional regulator (LacI family BTG_17845 ENOG4105C0R drug resistance transporter emrb qaca subfamily BTG_17850 ENOG41067TZ transcriptional regulator, MarR family BTG_17855 ENOG4105CXY transporter BTG_17865 ENOG41068KF Universal stress protein BTG_17870 ENOG4105CHH sulfate transporter BTG_17895 ENOG4105BZU Histidine kinase BTG_17900 ENOG4105NAE bifunctional deaminase-reductase domain protein BTG_17905 ENOG4105D29 Helix-turn-helix type 11 domain protein BTG_17915 ENOG4105GFR rna polymerase sigma factor BTG_17930 ENOG4108IQI permease BTG_17940 ENOG4105DRP amino acid AbC transporter BTG_17945 ENOG4105EAD ABC transporter BTG_17950 ENOG4105CT1 (ABC) transporter BTG_17955 ENOG4105CDA abc transporter atp-binding protein BTG_17965 ENOG4105BZG amino acid carrier protein BTG_17970 ENOG4105CRN Aminoglycoside phosphotransferase BTG_17980 ENOG4105E1K spore germination protein BTG_18000 ENOG4105CG3 alpha amylase, catalytic region BTG_18005 ENOG4105C5Y PTS System BTG_18010 ENOG4107414 GntR family transcriptional regulator BTG_18015 ENOG4105D5Q Arginine ornithine antiporter BTG_18020 ENOG4105BZU Histidine kinase BTG_18030 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BTG_18035 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BTG_18040 ENOG4107T89 von Willebrand factor, type A BTG_18050 ENOG4105EXW epimerase dehydratase BTG_18075 ENOG4108IHU transport system permease protein BTG_18080 ENOG4105DQ5 transport system permease protein BTG_18085 ENOG4108MES Periplasmic binding protein BTG_18090 ENOG4105DUX Transporter BTG_18105 ENOG4105DAA L-lactate BTG_18110 ENOG4108IJ0 Aspartate ammonia-lyase BTG_18115 ENOG4105C37 (CBS) domain BTG_18120 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BTG_18125 ENOG4105D9N nucleoside BTG_18130 ENOG4108KGH TRANSCRIPTIONal BTG_18135 ENOG41073R8 VanW family BTG_18170 ENOG4105DAP Nicotinate phosphoribosyltransferase BTG_18175 ENOG4105C59 p-type ATPase BTG_18185 ENOG4105CUB amino acid BTG_18205 ENOG4108JB9 formate dehydrogenase BTG_18210 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BTG_18240 ENOG4105BZU Histidine kinase BTG_18250 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BTG_18255 ENOG4108UZ3 Transporter BTG_18265 ENOG4105C6K Malic enzyme BTG_18275 ENOG4108MRH transcriptional regulatory protein BTG_18300 ENOG4105US7 Histidine kinase BTG_18305 ENOG4108STX response regulator BTG_18310 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BTG_18315 ENOG4105BZ7 extracellular solute-binding protein family 1 BTG_18320 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BTG_18325 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BTG_18330 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BTG_18335 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BTG_18365 ENOG4105D4T Citrate transporter BTG_18370 ENOG4108V9W transcriptional regulatory protein BTG_18375 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BTG_18385 ENOG4105DZ6 Band 7 protein BTG_18400 ENOG4105C94 Transporter BTG_18415 ENOG4105CYN Serine protein kinase BTG_18425 ENOG4105BZU Histidine kinase BTG_18430 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BTG_18440 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BTG_18445 ENOG4108R9S DSBA oxidoreductase BTG_18450 ENOG4108JQC penicillin-binding protein 1A BTG_18485 ENOG4105G5W regulator Fur family BTG_18490 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BTG_18510 ENOG4108IUW ABC transporter BTG_18520 ENOG4105CBC glutamate synthase BTG_18525 ENOG4107NBY Membrane BTG_18530 ENOG4105BZ1 (ABC) transporter BTG_18555 ENOG4106BXE BTG_18560 ENOG4105CEN a g-specific adenine glycosylase BTG_18565 ENOG41067AE Membrane-bound metal-dependent hydrolase BTG_18595 ENOG4105ECP epimerase BTG_18600 ENOG4105CI2 imidazolone-5-propionate hydrolase BTG_18620 ENOG4105F1A Pyruvate formate-lyase BTG_18630 ENOG4105CKK Glycosyl transferase, family 2 BTG_18635 ENOG4105C3I Nad-dependent epimerase dehydratase BTG_18640 ENOG4107QQG Dehydrogenase BTG_18645 ENOG4107R51 Glycosyl transferase, family 2 BTG_18660 ENOG4108A04 Beta-lactamase BTG_18670 ENOG4105CSV Glutaminase BTG_18700 ENOG4108IQI permease BTG_18710 ENOG4108JUB Transcriptional regulator BTG_18720 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BTG_18730 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BTG_18765 ENOG4105UPD Calcium Proton BTG_18770 ENOG410606W general stress protein BTG_18785 ENOG4107ZTW SNARE associated Golgi BTG_18800 ENOG4105C3F Signal peptidase i BTG_18810 ENOG4108IPJ Membrane BTG_18815 ENOG4105C59 p-type ATPase BTG_18820 ENOG4107U9T Pfam:Ribonuclease_BN BTG_18830 ENOG4105KJF protein tyrosine phosphatase BTG_18835 ENOG41068PA UPF0435 protein BTG_18850 ENOG4108TTB tellurium resistance protein BTG_18855 ENOG4107TS3 membrane protein, TerC BTG_18860 ENOG4106FN3 tellurium resistance protein BTG_18865 ENOG4106FN3 tellurium resistance protein BTG_18870 ENOG4108N0M stress protein BTG_18900 ENOG4105DEU major facilitator superfamily BTG_18915 ENOG41062JF Transcriptional regulator BTG_18945 ENOG4105C5H ABC transporter BTG_18955 ENOG4105D2X ABC transporter substrate-binding protein BTG_18960 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BTG_18990 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BTG_19005 ENOG4105C9U ATP-dependent DNA helicase RecQ BTG_19020 ENOG4105CI1 PTS System BTG_19045 ENOG4108W63 CRP FNR family transcriptional regulator BTG_19050 ENOG4105C5B carbamate kinase BTG_19060 ENOG4105DBV ornithine carbamoyltransferase BTG_19075 ENOG4105C8Q Methyl-accepting chemotaxis BTG_19085 ENOG4105EAB amino acid AbC transporter BTG_19090 ENOG4105E5Q amino acid AbC transporter BTG_19105 ENOG4105D2S major facilitator superfamily BTG_19110 ENOG410756H nucleotidyltransferase BTG_19130 ENOG4105BZU Histidine kinase BTG_19150 ENOG4106UIA BTG_19155 ENOG4106UIA BTG_19175 ENOG4108V5C ABC transporter BTG_19180 ENOG4105DQ5 transport system permease protein BTG_19185 ENOG4105EHG Permease protein BTG_19190 ENOG4107W7X Aldolase BTG_19195 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) BTG_19200 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BTG_19205 ENOG4105D3R alkyl hydroperoxide reductase BTG_19230 ENOG4105DFD Na H antiporter BTG_19240 ENOG4105DTQ mandelate racemase muconate lactonizing BTG_19260 ENOG4108W15 Protein of unknown function (DUF1456) BTG_19270 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BTG_19275 ENOG4105D9N nucleoside BTG_19305 ENOG4105KPY Small multidrug resistance protein BTG_19310 ENOG4105C26 Dehydrogenase BTG_19320 ENOG4108JPW Aminotransferase BTG_19330 ENOG4105CBD Diacylglycerol kinase BTG_19350 ENOG4107I77 yiaA/B two helix domain BTG_19355 ENOG410834F Transcriptional regulator BTG_19375 ENOG4105D01 (LipO)protein BTG_19380 ENOG4108UMI ABC transporter, permease BTG_19385 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BTG_19390 ENOG4108W2Y isochorismatase BTG_19415 ENOG4105C4R Atp-dependent dna helicase BTG_19440 ENOG4105C12 Phosphoribosylglycinamide synthetase BTG_19450 ENOG4108V3E phosphoribosylglycinamide formyltransferase BTG_19475 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BTG_19485 ENOG4105C83 adenylosuccinate lyase BTG_19490 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BTG_19495 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BTG_19505 ENOG410631K Membrane BTG_19540 ENOG4107ZXU DSBA oxidoreductase BTG_19550 ENOG4105BZU Histidine kinase BTG_19560 ENOG4105C7N Xanthine uracil vitamin C permease BTG_19570 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BTG_19595 ENOG4107QZI cell division protein FtsK BTG_19660 ENOG4108TYN CAAX amino terminal protease family protein BTG_19675 ENOG4105C5H ABC transporter BTG_19680 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BTG_19685 ENOG410801F ribosomal-protein-alanine acetyltransferase BTG_19690 ENOG41072GX Peptidase M22 Glycoprotease BTG_19695 ENOG4105K8N protein family UPF0079, ATPase BTG_19720 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BTG_19730 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BTG_19735 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BTG_19760 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BTG_19765 ENOG4105CPF Cell wall formation (By similarity) BTG_19770 ENOG4108SC4 )-transporter BTG_19775 ENOG4105CUB amino acid BTG_19785 ENOG4105ERH Fumarylacetoacetate hydrolase BTG_19790 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BTG_19810 ENOG410667J hydrolase BTG_19815 ENOG4108JQ7 (ABC) transporter BTG_19820 ENOG4105C3U ABC transporter BTG_19825 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BTG_19835 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BTG_19845 ENOG4105C5H ABC transporter BTG_19870 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BTG_19890 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BTG_19915 ENOG4105F6E Acyl-transferase BTG_19950 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BTG_19955 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BTG_19960 ENOG4105E0C molybdate abc transporter BTG_19985 ENOG4108J59 Extracellular solute-binding protein, family 5 BTG_19990 ENOG4108J59 Extracellular solute-binding protein, family 5 BTG_20010 ENOG4108JQ7 (ABC) transporter BTG_20015 ENOG4105C3U ABC transporter BTG_20020 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BTG_20025 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BTG_20045 ENOG4105C2C drug resistance transporter, Bcr CflA BTG_20060 ENOG4105IQ5 FAD linked oxidase domain protein BTG_20070 ENOG4105CB2 alcohol dehydrogenase BTG_20075 ENOG4105D01 (LipO)protein BTG_20080 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BTG_20085 ENOG4108UMI ABC transporter, permease BTG_20090 ENOG4108PSK reductase BTG_20110 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BTG_20125 ENOG4107U5W ybbr family BTG_20130 ENOG4105C8B TIGR00159 family BTG_20150 ENOG4108NMV polysaccharide deacetylase BTG_20165 ENOG4105D1F ATP-binding protein BTG_20190 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BTG_20195 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BTG_20200 ENOG4108JJB ABC transporter BTG_20205 ENOG4108JJB ABC transporter BTG_20230 ENOG41067V7 50S ribosomal protein L36 BTG_20240 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BTG_20250 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BTG_20275 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BTG_20385 ENOG4105XPM ribosomal protein BTG_20390 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BTG_20400 ENOG4107Y49 methyltransferase BTG_20425 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BTG_20440 ENOG4105QIV RNA polymerase BTG_20445 ENOG4105M0M Tetracycline resistance protein BTG_20450 ENOG4105C2N RNA methyltransferase TrmH family group 3 BTG_20465 ENOG4105D7W serine acetyltransferase BTG_20485 ENOG4105CTP PilT protein domain protein BTG_20495 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BTG_20510 ENOG4108Z0C Uvrb UvrC protein BTG_20525 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BTG_20535 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BTG_20540 ENOG4105KRF dihydroneopterin aldolase BTG_20545 ENOG4105EEI dihydropteroate synthase BTG_20550 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BTG_20555 ENOG4105DDQ anthranilate synthase BTG_20560 ENOG4105CRQ synthase (Component I) BTG_20565 ENOG4105C6T cysteine synthase BTG_20580 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BTG_20585 ENOG4108UGV hypoxanthine phosphoribosyltransferase BTG_20590 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BTG_20600 ENOG41060GV RNA binding s1 domain protein BTG_20615 ENOG4105VYY sporulation protein yabp BTG_20620 ENOG41082I2 s4 domain protein BTG_20625 ENOG4108IY2 MazG family BTG_20635 ENOG4108M14 stage v sporulation protein t BTG_20640 ENOG4108JA2 transcriptioN-repair coupling factor BTG_20650 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BTG_20655 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BTG_20670 ENOG4105KME endoribonuclease L-psp BTG_20675 ENOG4105DFT pur operon repressor BTG_20690 ENOG4105W42 Veg protein BTG_20695 ENOG4105XFA sporulation peptidase YabG BTG_20705 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BTG_20710 ENOG4105F8V Hydrolase, tatD family BTG_20715 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BTG_20720 ENOG4105KRN Transcriptional regulator, abrb family BTG_20725 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BTG_20735 ENOG41060K3 Methyltransferase BTG_20745 ENOG4105MA4 psp1 domain protein BTG_20750 ENOG4105FA2 dna polymerase iii BTG_20760 ENOG4105CXN decarboxylase BTG_20770 ENOG41067KS pro-sigma K processing BTG_20790 ENOG4105C6E dna polymerase iii BTG_20795 ENOG4108Z6B deaminase BTG_20800 ENOG4105GTG Isochorismatase BTG_20810 ENOG4105ZMH deoxynucleoside kinase BTG_20840 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BTG_20850 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BTG_20865 ENOG410848D S4 domain protein YaaA BTG_20870 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BTG_20890 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BTG_20900 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BTG_20920 ENOG4107QJE Chromosome Partitioning Protein BTG_20925 ENOG4105FA0 parb-like partition protein BTG_20930 ENOG4108ZDA Sporulation protein YyaC BTG_20935 ENOG4105D8X mechanosensitive ion channel BTG_20940 ENOG4105VDK protein, conserved in bacteria BTG_20945 ENOG4105C3G gtp-binding protein BTG_20955 ENOG4108UUM single-stranded DNA-binding protein BTG_20965 ENOG4108XMW Membrane BTG_20970 ENOG4105BZR domain protein BTG_20980 ENOG4105CDU Replicative dna helicase BTG_20985 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BTG_20990 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_20995 ENOG4105BZU Histidine kinase BTG_21010 ENOG4105Q2H domain protein BTG_21015 ENOG4105C0H protease BTG_21100 ENOG4105DPN Oligoendopeptidase f BTG_21105 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) BTG_21110 ENOG4105C1J atp-dependent rna helicase BTG_21120 ENOG4108UT2 hemolysin iii BTG_21125 ENOG4105CMR udp-glucose 4-epimerase BTG_21140 ENOG4105IW1 AmiS UreI transporter BTG_21150 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BTG_21165 ENOG4107RGD Major Facilitator superfamily BTG_21170 ENOG4108HRK Histidine kinase BTG_21175 ENOG4108NEV two component transcriptional regulator, LytTR family BTG_21190 ENOG4106F5Q Membrane BTG_21195 ENOG4105E0X reductase BTG_21205 ENOG41067SE Tetr family transcriptional regulator BTG_21210 ENOG4105C5H ABC transporter BTG_21215 ENOG4108IG5 Transcriptional regulator BTG_21225 ENOG4105CKK Glycosyl transferase, family 2 BTG_21230 ENOG4105EJV Membrane BTG_21240 ENOG4105K64 Glycosyl transferase, family 2 BTG_21255 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BTG_21260 ENOG4108S4H thioesterase Superfamily protein BTG_21270 ENOG4106YBV Methyl-accepting chemotaxis BTG_21275 ENOG4105EN6 Membrane BTG_21285 ENOG4105CG5 Glycosyl transferase (Group 1 BTG_21295 ENOG41079KZ Major Facilitator Superfamily BTG_21300 ENOG4105DY9 regulatoR BTG_21305 ENOG4105D22 carbon starvation protein BTG_21310 ENOG4105VCD cytoplasmic protein BTG_21315 ENOG4105BZU Histidine kinase BTG_21320 ENOG4105DWF phosphomethylpyrimidine kinase BTG_21325 ENOG4105BZU Histidine kinase BTG_21330 ENOG4105WH1 Two component transcriptional regulator luxr family BTG_21340 ENOG4108Y4K DNA-binding transcriptional activator BTG_21365 ENOG4105D6E homoserine dehydrogenase BTG_21380 ENOG41090WU lipolytic protein G-D-S-L family BTG_21385 ENOG4105CJ1 ABC, transporter BTG_21390 ENOG4108TU7 Inherit from COG: (ABC) transporter BTG_21400 ENOG4105VCH membrane BTG_21405 ENOG410667J hydrolase BTG_21415 ENOG4107SVH Potassium channel protein BTG_21435 ENOG4108VKI Cell wall hydrolase BTG_21445 ENOG4107UEZ chlorite dismutase BTG_21450 ENOG4108IJ2 phosphate acetyltransferase BTG_21455 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BTG_21460 ENOG4108VCI transcription factor, rsfa family BTG_21470 ENOG4105DQ5 transport system permease protein BTG_21475 ENOG4105EHG Permease protein BTG_21480 ENOG4105E0A ABC, transporter BTG_21485 ENOG4108MES Periplasmic binding protein BTG_21490 ENOG4105DCI Phosphohydrolase BTG_21495 ENOG41069HH 4-oxalocrotonate tautomerase BTG_21500 ENOG4108Z4T Peptidase M50 BTG_21505 ENOG4108XFG YwhD family BTG_21510 ENOG4105BZ4 penicillin-binding protein BTG_21515 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BTG_21525 ENOG4107SWG transcriptional regulator MERR family BTG_21530 ENOG4105DXB Major Facilitator superfamily BTG_21540 ENOG4105CYW agmatinase BTG_21560 ENOG410684U Domain of unknown function (DUF1934) BTG_21570 ENOG4105EMN RNA polymerase sigma factor BTG_21585 ENOG4105IIU Aminopeptidase BTG_21595 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BTG_21600 ENOG4108M15 ABC transporter BTG_21605 ENOG4105KCT ABC transporter BTG_21610 ENOG4105BZU Histidine kinase BTG_21620 ENOG4105D4Y metalloprotease BTG_21635 ENOG4105BZU Histidine kinase BTG_21650 ENOG4105DF6 Fe-S oxidoreductase BTG_21660 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BTG_21665 ENOG4105C1G acyl-Coa dehydrogenase BTG_21670 ENOG4105C1G acyl-Coa dehydrogenase BTG_21675 ENOG4105C1G acyl-Coa dehydrogenase BTG_21710 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BTG_21720 ENOG4105CBT Fructose-1,6-bisphosphatase BTG_21725 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BTG_21740 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BTG_21745 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BTG_21750 ENOG4108ZXQ stage ii sporulation protein r BTG_21760 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BTG_21785 ENOG4107XC4 flavin reductase domain protein, FMN-binding BTG_21790 ENOG4108VGI doxx family BTG_21805 ENOG4108YZG isomerase BTG_21810 ENOG4108UIC UPF0340 protein BTG_21835 ENOG41062M3 atp synthase BTG_21840 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BTG_21890 ENOG4105BZU Histidine kinase BTG_21895 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BTG_21905 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BTG_21910 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BTG_21935 ENOG4105D65 subunit l BTG_21940 ENOG4105C8S subunit m BTG_21945 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BTG_21950 ENOG4106778 Protein of unknown function (DUF1146) BTG_21970 ENOG4105DY9 regulatoR BTG_21985 ENOG4105FRN stage II sporulation protein BTG_21995 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BTG_22010 ENOG4107YJ4 chain length determinant protein BTG_22015 ENOG4105HTX biosynthesis protein BTG_22020 ENOG4107YJ4 chain length determinant protein BTG_22025 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BTG_22030 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BTG_22035 ENOG4105D3Q Sugar transferase BTG_22050 ENOG4105CPK Glycosyl transferase (Group 1 BTG_22060 ENOG4105C6Y Udp-glucose 6-dehydrogenase BTG_22065 ENOG4105CMR udp-glucose 4-epimerase BTG_22070 ENOG4108KGH TRANSCRIPTIONal BTG_22080 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_22085 ENOG4105BZU Histidine kinase BTG_22100 ENOG4105CXY transporter BTG_22110 ENOG4105C19 ABC transporter BTG_22115 ENOG4107RBB ABC transporter, permease BTG_22125 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_22155 ENOG4105C0D helicase BTG_22160 ENOG4105KBK Zinc finger, swim domain protein BTG_22190 ENOG41069ER domain protein BTG_22195 ENOG4105C94 Transporter BTG_22205 ENOG4107R8N Glycosyl transferase, family 2 BTG_22240 ENOG4105E0M Sulfatase BTG_22250 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BTG_22260 ENOG4105DAA L-lactate BTG_22295 ENOG4107RSM transcriptional regulator BTG_22300 ENOG4105ECB domain protein BTG_22320 ENOG4105VZJ PTS System BTG_22330 ENOG4105VCP PTS System BTG_22335 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BTG_22340 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BTG_22350 ENOG4105CK1 PTS System BTG_22355 ENOG4105VCP PTS System BTG_22360 ENOG4105F8D glycoside hydrolase family 4 BTG_22380 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BTG_22390 ENOG4105ESV Glycosyl transferase, family 4 BTG_22395 ENOG4105C6Y Udp-glucose 6-dehydrogenase BTG_22400 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BTG_22405 ENOG4108KGH TRANSCRIPTIONal BTG_22410 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BTG_22420 ENOG4105KVH Transcriptional regulator BTG_22435 ENOG41081UC Inherit from COG: Competence protein BTG_22440 ENOG4105VEQ Cold shock protein BTG_22445 ENOG4105MS2 ribosomal subunit Interface protein BTG_22475 ENOG4108RDQ ABC transporter BTG_22510 ENOG4105CAK Cell division ATP-binding protein ftsE BTG_22515 ENOG4105CRP Part of the ABC transporter FtsEX involved in BTG_22520 ENOG4105CN1 protease BTG_22530 ENOG4105BZ1 (ABC) transporter BTG_22540 ENOG4105C5H ABC transporter BTG_22545 ENOG4108WS4 fmn reductase BTG_22555 ENOG4105DUM transcriptional regulator, lysR family BTG_22560 ENOG4105HMI Membrane BTG_22575 ENOG4107TXC Transcriptional regulator BTG_22595 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BTG_22605 ENOG41086DT Membrane protein of unknown function BTG_22625 ENOG4108S4C acetyltransferase BTG_22635 ENOG4105C3M thioredoxin reductase BTG_22645 ENOG4108Z4K mutator MutT protein BTG_22655 ENOG4105CHW UPF0052 protein BTG_22665 ENOG4105KRI phosphocarrier protein (HPr BTG_22675 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BTG_22680 ENOG4105H67 Protein of unknown function (DUF421) BTG_22695 ENOG4105CZ3 stage V sporulation protein ad BTG_22700 ENOG41090VF Stage v sporulation protein ac BTG_22720 ENOG4105VTR Integrase BTG_22750 ENOG4106050 phage regulatory protein, rha family BTG_22820 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BTG_22970 ENOG4105XSJ toxin secretion phage lysis holin BTG_22975 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase BTG_23000 ENOG4108W5X Transcriptional Regulator, LuxR family BTG_23005 ENOG4105BZU Histidine kinase BTG_23010 ENOG4108IUX (ABC) transporter BTG_23015 ENOG4105RHA ABC transporter, permease BTG_23025 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_23075 ENOG41067MG lrgb family BTG_23080 ENOG4105XZU Preprotein translocase, subunit SecG BTG_23090 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BTG_23110 ENOG4105DQ6 Transposase BTG_23130 ENOG4105CM4 permease protein BTG_23135 ENOG4108IPW abc transporter atp-binding protein BTG_23155 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) BTG_23160 ENOG4108V2W Carbonate dehydratase BTG_23180 ENOG4108W2Y isochorismatase BTG_23190 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BTG_23200 ENOG4108MK9 spermidine N(1)-acetyltransferase BTG_23205 ENOG4105C5H ABC transporter BTG_23225 ENOG4105WMR Protein CrcB homolog BTG_23240 ENOG4105C8Q Methyl-accepting chemotaxis BTG_23250 ENOG4105D4A Cell wall formation (By similarity) BTG_23255 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BTG_23270 ENOG4105KVH Transcriptional regulator BTG_23275 ENOG4105F27 Major Facilitator BTG_23280 ENOG4105CV8 reductase BTG_23295 ENOG4108RYK Nad-dependent epimerase dehydratase BTG_23310 ENOG4105D9N nucleoside BTG_23315 ENOG4105D9N nucleoside BTG_23335 ENOG4108URH decarboxylase BTG_23355 ENOG4108RMU ferritin dps family protein BTG_23370 ENOG4105NCW Trka-c domain protein BTG_23375 ENOG4107S91 Sodium hydrogen exchanger BTG_23380 ENOG4107T5V SNARE associated Golgi BTG_23395 ENOG4105C2I pirin domain protein BTG_23400 ENOG4105D4Y metalloprotease BTG_23405 ENOG4105VG1 fes assembly suf system protein BTG_23410 ENOG4105C8Q Methyl-accepting chemotaxis BTG_23415 ENOG4105C8Q Methyl-accepting chemotaxis BTG_23440 ENOG4105BZU Histidine kinase BTG_23445 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_23450 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BTG_23460 ENOG4107ZTW SNARE associated Golgi BTG_23495 ENOG4107AYK membrAne BTG_23505 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BTG_23520 ENOG4107R7I amino acid BTG_23525 ENOG4108SUT Major Facilitator Superfamily BTG_23540 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BTG_23560 ENOG4105DZ1 carboxypeptidase BTG_23575 ENOG4105CHU acetyl-coa acetyltransferase BTG_23580 ENOG4105C1G acyl-Coa dehydrogenase BTG_23585 ENOG4108W8B Beta-lactamase domain protein BTG_23600 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BTG_23620 ENOG41080E8 Transcriptional regulator, Spx MgsR family BTG_23660 ENOG4108UMI ABC transporter, permease BTG_23665 ENOG4105D01 (LipO)protein BTG_23670 ENOG4105D01 (LipO)protein BTG_23675 ENOG4105C3K feS assembly ATPase SufC BTG_23680 ENOG4105JRK feS assembly protein SufD BTG_23685 ENOG4105C9B Cysteine desulfurase BTG_23690 ENOG4108UNV SUF system FeS assembly protein, NifU family BTG_23695 ENOG4105DIW FeS assembly protein SUFB BTG_23700 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BTG_23705 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BTG_23725 ENOG4106050 phage regulatory protein, rha family BTG_23795 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BTG_23935 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BTG_23960 ENOG4107R8B 5'-nucleotidase BTG_23965 ENOG4105KZD Domain of unknown function (DUF1805) BTG_23970 ENOG4108YTE sporulation protein YunB BTG_23975 ENOG4105FAA peptidase M23 BTG_24000 ENOG41090T1 Membrane BTG_24005 ENOG4107TXC Transcriptional regulator BTG_24010 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BTG_24015 ENOG4105MMD transcriptional regulator BTG_24030 ENOG4105CBT Fructose-1,6-bisphosphatase BTG_24045 ENOG4105D4U had-superfamily hydrolase, subfamily iia BTG_24055 ENOG4105DYS nad(p)h dehydrogenase (quinone) BTG_24065 ENOG4105DAX Pfam:DUF2983 BTG_24085 ENOG4108W5N phosphatidylglycerophosphatase a BTG_24100 ENOG41083MR nifu domain-containing protein BTG_24155 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BTG_24160 ENOG4105C4B ABC transporter, permease BTG_24165 ENOG4108JJA ABC, transporter BTG_24190 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BTG_24220 ENOG4105EWC Purine nucleoside phosphorylase BTG_24245 ENOG4105CEP NADH dehydrogenase BTG_24260 ENOG41069ER domain protein BTG_24280 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BTG_24285 ENOG4105DQ6 Transposase BTG_24305 ENOG4105KA0 thioesterase Superfamily protein BTG_24310 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BTG_24325 ENOG4107R3E Citrate transporter BTG_24335 ENOG4105Y38 Kinase-associated protein B BTG_24350 ENOG4105C87 Aminotransferase class I and II BTG_24365 ENOG4108MUZ hydrolase BTG_24370 ENOG4105C5I Dehydrogenase BTG_24375 ENOG4108ZB6 transcriptional regulator AsnC family BTG_24380 ENOG4105CHM Aminotransferase BTG_24390 ENOG4105WG9 Conserved Protein BTG_24405 ENOG4107PBV potassium channel BTG_24410 ENOG4105KT7 mgtC SapB transporter BTG_24425 ENOG4108Q5F Tetr family transcriptional regulator BTG_24430 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BTG_24450 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BTG_24500 ENOG4105VEQ Cold shock protein BTG_24510 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BTG_24515 ENOG4105E4F Isochorismate synthase BTG_24525 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BTG_24530 ENOG4108IPT Naphthoate synthase BTG_24540 ENOG4105DTQ mandelate racemase muconate lactonizing BTG_24560 ENOG41069H0 dihydroorotase EC 3.5.2.3 BTG_24580 ENOG4105FDP GntR family transcriptional regulator BTG_24585 ENOG4105C6Z Gluconate BTG_24630 ENOG41082BM Transcriptional regulator, arsr family BTG_24640 ENOG4105CJ1 ABC, transporter BTG_24650 ENOG41086D8 Transcriptional regulator BTG_24715 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BTG_24720 ENOG4108UGV hypoxanthine phosphoribosyltransferase BTG_24745 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BTG_24750 ENOG4105BZU Histidine kinase BTG_24755 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BTG_24780 ENOG41087YS Phage shock protein A BTG_24825 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BTG_24830 ENOG4105C4M (Ubiquinol oxidase) subunit I BTG_24835 ENOG4108V2W Carbonate dehydratase BTG_24855 ENOG410839T multidrug resistance protein BTG_24860 ENOG41080TC multidrug resistance protein BTG_24915 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BTG_24925 ENOG4105D2X ABC transporter substrate-binding protein BTG_24950 ENOG4107T7U Sulfatase BTG_24955 ENOG4107S9D Alpha beta hydrolase BTG_24970 ENOG4105BZU Histidine kinase BTG_24975 ENOG4105BZU Histidine kinase BTG_25060 ENOG4105EPU Molybdenum cofactor synthesis domain protein BTG_25070 ENOG4105BZF Glycosyl transferase (Group 1 BTG_25075 ENOG4105YVM Phosphoesterase, PA-phosphatase related BTG_25080 ENOG4108Z0R Transferase BTG_25085 ENOG4105E8V Alpha Beta Hydrolase Fold protein BTG_25110 ENOG4105N5T Radical SAM Protein BTG_25130 ENOG4105C19 ABC transporter BTG_25145 ENOG4105NCW Trka-c domain protein BTG_25150 ENOG4107S91 Sodium hydrogen exchanger BTG_25155 ENOG410605W Major Facilitator BTG_25185 ENOG4108B31 Spore germination protein BTG_25195 ENOG4105DWV Homoserine O-trans-acetylase BTG_25205 ENOG41085GJ domain protein BTG_25225 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BTG_25230 ENOG4105D06 uba thif-type nad fad binding protein BTG_25240 ENOG4105CVM Molybdenum cofactor synthesis domain protein BTG_25245 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BTG_25250 ENOG4108ZAF Molybdopterin BTG_25265 ENOG4105CSC Glucose uptake protein BTG_25270 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BTG_25275 ENOG4108VJ1 Transcriptional regulator (CarD family BTG_25310 ENOG4105CBX hi0933 family BTG_25325 ENOG4105YW5 deoR family transcriptional regulator BTG_25330 ENOG4107QSE Dipeptidase BTG_25340 ENOG4108IUM Glycogen debranching enzyme BTG_25345 ENOG4108V15 phosphotransferase enzyme family BTG_25360 ENOG4105C8F Beta-lactamase domain protein BTG_25390 ENOG4108VDD TRNA binding domain protein BTG_25425 ENOG4108IPJ Membrane BTG_25445 ENOG4105C88 aminopeptidase BTG_25465 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BTG_25470 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BTG_25475 ENOG4105ETE Transcriptional regulator (LacI family BTG_25505 ENOG4105EP9 oxidoreductase BTG_25510 ENOG4107SNB ankyrin repeat protein YahD BTG_25515 ENOG4105BZU Histidine kinase BTG_25520 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BTG_25535 ENOG4105DGU Histone deacetylase BTG_25540 ENOG4105W87 Cbs domain BTG_25545 ENOG4105F1V Acetoin utilization protein BTG_25555 ENOG4108UW5 maltose o-acetyltransferase BTG_25580 ENOG4108IBT Inherit from COG: transposase BTG_25590 ENOG4105C28 cystathionine BTG_25600 ENOG4105U5Y Transcriptional regulator BTG_25610 ENOG4105RQF LysR family Transcriptional regulator BTG_25635 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BTG_25645 ENOG4105EFZ amidohydrolase BTG_25660 ENOG4105KBJ sporulation protein ytfj BTG_25665 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BTG_25675 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BTG_25695 ENOG4108JYZ YitT family BTG_25735 ENOG4107YZX Universal stress protein BTG_25755 ENOG41082W1 Cupin 2, conserved barrel domain protein BTG_25760 ENOG4105Z7P Acetyltransferase (GNAT) family BTG_25800 ENOG4105DC7 peptidase M24 BTG_25825 ENOG4105SFS phosphoesterase RecJ domain protein BTG_25835 ENOG4105VV2 BTG_25840 ENOG4105C0B DNA polymerase III (alpha subunit) BTG_25845 ENOG4105C6K Malic enzyme BTG_25850 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BTG_25875 ENOG4105FS0 cytoplasmic membrane protein BTG_25880 ENOG4108REF Sporulation integral membrane protein ytvi BTG_25890 ENOG4105BZN citrate synthase BTG_25895 ENOG4108HMX isocitrate dehydrogenase (NADP) BTG_25920 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BTG_25925 ENOG4105BZU Histidine kinase BTG_25930 ENOG4105C2M dna polymerase I BTG_25935 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BTG_25945 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BTG_25950 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BTG_25955 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BTG_25975 ENOG4105DQ6 Transposase BTG_25990 ENOG4108TDW sporulation protein YtxC BTG_25995 ENOG4105C22 threonyL-tRNA synthetase BTG_26000 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BTG_26020 ENOG4105CN9 Peptidase m42 family protein BTG_26025 ENOG4108JGH Tetr family transcriptional regulator BTG_26030 ENOG4105CW7 secretion protein, HlyD family BTG_26035 ENOG4105C0R drug resistance transporter emrb qaca subfamily BTG_26060 ENOG4108RWN rrna methyltransferase BTG_26070 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BTG_26075 ENOG4105C5S asparaginyl-tRNA synthetase BTG_26090 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BTG_26105 ENOG4105DCG PHP domain protein BTG_26120 ENOG4105FE9 pseudouridine synthase BTG_26130 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BTG_26140 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BTG_26155 ENOG4105E0A ABC, transporter BTG_26160 ENOG4105KFN sortase, SrtB family BTG_26170 ENOG4105DR4 Methyltransferase BTG_26185 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BTG_26230 ENOG4105S6R Iron-hydroxamate transporter permease subunit BTG_26250 ENOG4105CEY Amp-dependent synthetase and ligase BTG_26255 ENOG4107Z3H Transcriptional regulator, TetR family BTG_26260 ENOG41060WC Enoyl-CoA hydratase BTG_26265 ENOG4105BZJ Electron transfer flavoprotein BTG_26270 ENOG4105C10 Electron transfer flavoprotein BTG_26275 ENOG4105K63 Thioredoxin BTG_26290 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BTG_26300 ENOG4105E33 succinate dehydrogenase BTG_26310 ENOG4108VXD carboxy-peptidase BTG_26315 ENOG4105E14 MotA TolQ exbB proton channel BTG_26320 ENOG4105ER2 Ompa motb domain protein BTG_26325 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BTG_26330 ENOG4108IUX (ABC) transporter BTG_26335 ENOG4105RHA ABC transporter, permease BTG_26340 ENOG4108Z40 Transcriptional regulator BTG_26345 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BTG_26355 ENOG4108JCI Transcriptional regulator BTG_26360 ENOG41067S9 phage shock protein C, PspC BTG_26365 ENOG4105DZC cytosine deaminase BTG_26375 ENOG4105PFC Transcriptional regulator BTG_26385 ENOG4105KBX Transcriptional regulator, TetR family BTG_26395 ENOG4108PCX Major Facilitator BTG_26405 ENOG4108XJQ germination protein BTG_26420 ENOG4105M59 Phosphodiesterase, mj0936 family BTG_26430 ENOG4108QCI YvbH-like oligomerisation region BTG_26455 ENOG4108IUQ atp-dependent protease BTG_26475 ENOG4105K56 Transcriptional regulator BTG_26500 ENOG4105D52 delta-aminolevulinic acid dehydratase BTG_26510 ENOG41068KH stage VI sporulation protein D BTG_26520 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BTG_26525 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BTG_26545 ENOG4107Y5K Resolvase BTG_26770 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BTG_26795 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BTG_26810 ENOG4105DFF Rod shape-determining protein mreb BTG_26815 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BTG_26830 ENOG4107QMS site-determining protein BTG_26845 ENOG4105C03 ribonuclease BTG_26855 ENOG4105X36 (ribosomal) protein BTG_26880 ENOG4105EWM Histidine kinase BTG_26885 ENOG4105C19 ABC transporter BTG_26900 ENOG4105CQC Prephenate dehydratase BTG_26910 ENOG4108RPX mosc domain containing protein BTG_26925 ENOG4108IYU L-aspartate oxidase BTG_26930 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BTG_26960 ENOG4108HUF Transporter BTG_26975 ENOG41061AI Protein of unknown function (DUF2905) BTG_26990 ENOG4105VIE preprotein translocase, subunit YajC BTG_27000 ENOG4108QG2 Membrane BTG_27005 ENOG4105CKP Polysaccharide Biosynthesis Protein BTG_27015 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BTG_27020 ENOG41076HS cation diffusion facilitator family transporter BTG_27025 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BTG_27035 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BTG_27055 ENOG4105CUT histidyl-tRNA synthetase BTG_27065 ENOG4105CUZ uba thif-type nad fad binding protein BTG_27070 ENOG4108VCI transcription factor, rsfa family BTG_27075 ENOG4105D1H recombination factor protein RarA BTG_27085 ENOG4105C3J Cysteine desulfurase BTG_27090 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BTG_27100 ENOG4105C7H Helicase, RecD TraA family BTG_27105 ENOG41060CR BTG_27120 ENOG4105C02 permease BTG_27130 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BTG_27150 ENOG4105HHA aminodeoxychorismate lyase BTG_27155 ENOG4108VQJ O-methyltransferase BTG_27160 ENOG4105XYU peptidase (U32 family) BTG_27165 ENOG4105CFP Peptidase U32 BTG_27175 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BTG_27185 ENOG4107XRG penicillin-binding protein BTG_27215 ENOG4105C28 cystathionine BTG_27220 ENOG4108EKI Dehydrogenase BTG_27225 ENOG4105DQ6 Transposase BTG_27240 ENOG4108V5C ABC transporter BTG_27245 ENOG4105S6R Iron-hydroxamate transporter permease subunit BTG_27285 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BTG_27295 ENOG4105MIR Phenylalanine 4-monooxygenase BTG_27305 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BTG_27340 ENOG4108MUZ hydrolase BTG_27345 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BTG_27350 ENOG4105G6Z alkaline phosphatase BTG_27360 ENOG4108TVJ Nitroreductase BTG_27380 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_27395 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BTG_27400 ENOG4105CQW ribosome biogenesis GTPase YqeH BTG_27410 ENOG410812S Rna-binding protein BTG_27420 ENOG4108WF2 Metal Dependent Phosphohydrolase BTG_27430 ENOG4105DXX methyltransferase BTG_27440 ENOG4105KQC Competence protein BTG_27445 ENOG4108UK2 deaminase BTG_27460 ENOG4105DHP deoxycytidine triphosphate deaminase BTG_27500 ENOG4108UK2 deaminase BTG_27505 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BTG_27515 ENOG4105TQK DNA polymerase iii, delta' subunit BTG_27540 ENOG4105KVH Transcriptional regulator BTG_27545 ENOG4105CSA Coproporphyrinogen iii oxidase BTG_27575 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BTG_27580 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BTG_27590 ENOG4105KTH gatB Yqey BTG_27600 ENOG41068P3 sporulation protein YqfC BTG_27610 ENOG4105C9A Phoh family BTG_27615 ENOG4105CTJ Metal Dependent Phosphohydrolase BTG_27625 ENOG4107YR5 Diacylglycerol kinase BTG_27630 ENOG4105KG3 cytidine deaminase BTG_27635 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BTG_27660 ENOG4107XJU UPF0178 protein BTG_27665 ENOG4107XJU UPF0178 protein BTG_27670 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BTG_27675 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_27690 ENOG4105EGD dinuclear metal center protein, YbgI family BTG_27715 ENOG41069ZM Protein of unknown function (DUF2624) BTG_27720 ENOG4108JYZ YitT family BTG_27725 ENOG4105FDK ABC transporter BTG_27735 ENOG4105N80 Ferric uptake regulator, Fur family BTG_27755 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BTG_27765 ENOG4107RF6 penicillin-binding protein BTG_27775 ENOG4105C8U phosphate abc transporter BTG_27780 ENOG4105C8U phosphate abc transporter BTG_27785 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BTG_27790 ENOG4108UTW Plays a role in the regulation of phosphate uptake BTG_27805 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BTG_27815 ENOG4105DKQ ROK family BTG_27825 ENOG4105C5X domain protein BTG_27850 ENOG4105C28 cystathionine BTG_27855 ENOG4105C28 cystathionine BTG_27865 ENOG4105C3R Methionine synthase BTG_27870 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BTG_27910 ENOG4107R6U sodium dicarboxylate symporter BTG_27955 ENOG4105VTR Integrase BTG_27985 ENOG4106050 phage regulatory protein, rha family BTG_28020 ENOG4105KRN Transcriptional regulator, abrb family BTG_28055 ENOG4107RHI Cytosine-specific methyltransferase BTG_28195 ENOG4105XSJ toxin secretion phage lysis holin BTG_28255 ENOG4105C0D helicase BTG_28285 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BTG_28290 ENOG4105CJ1 ABC, transporter BTG_28320 ENOG41080TC multidrug resistance protein BTG_28345 ENOG4105WZW rhodanese family BTG_28350 ENOG41082GG biotin lipoate A B protein ligase BTG_28380 ENOG4107YBY Hydrolase BTG_28390 ENOG4105CBJ Metal-dependent enzyme BTG_28405 ENOG4105DC7 peptidase M24 BTG_28430 ENOG4105CD2 stage iii sporulation protein aa BTG_28435 ENOG4105KR5 Stage iii sporulation protein BTG_28440 ENOG4108CQH stage III sporulation protein AC BTG_28445 ENOG4105KQ4 Stage iii sporulation protein ad BTG_28455 ENOG410644B Stage III sporulation protein af BTG_28475 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BTG_28480 ENOG4108ZSR alkaline shock protein BTG_28505 ENOG4105CTB Polyprenyl synthetase BTG_28515 ENOG4105DX0 Hemolysin A BTG_28520 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) BTG_28525 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BTG_28530 ENOG4105S1Z Stage IV sporulation protein B BTG_28535 ENOG4107QQR Sporulation BTG_28550 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BTG_28560 ENOG4108JUB Transcriptional regulator BTG_28575 ENOG4107RDP Dehydrogenase BTG_28595 ENOG4105CPP Dehydrogenase, E1 component BTG_28600 ENOG4105C7S Dehydrogenase BTG_28610 ENOG4108QY0 Membrane BTG_28620 ENOG4105G7B Protein of unknown function (DUF2992) BTG_28630 ENOG4108HW3 (ABC) transporter BTG_28635 ENOG4105E5Q amino acid AbC transporter BTG_28640 ENOG4105CDA abc transporter atp-binding protein BTG_28645 ENOG4108QEG Membrane BTG_28650 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BTG_28665 ENOG4105D9U N-acetyltransferase BTG_28670 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BTG_28690 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BTG_28720 ENOG4105EJQ L-serine dehydratase BTG_28725 ENOG4105II7 pyrroline-5-carboxylate reductase BTG_28730 ENOG41069FQ Metallo-beta-lactamase superfamily BTG_28735 ENOG4108IXY short-chain dehydrogenase reductase BTG_28750 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BTG_28765 ENOG4105DBV ornithine carbamoyltransferase BTG_28790 ENOG4105CGH 5'-nucleotidase BTG_28795 ENOG4105DFD Na H antiporter BTG_28805 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BTG_28820 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BTG_28825 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BTG_28850 ENOG4108R6K riboflavin synthase, subunit alpha BTG_28855 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BTG_28875 ENOG4108YM7 Gcn5-related n-acetyltransferase BTG_28880 ENOG4105ETE Transcriptional regulator (LacI family BTG_28890 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BTG_28915 ENOG4105RHY Pfam:UPF0157 BTG_28925 ENOG4105CPC Aldo Keto reductase BTG_28945 ENOG4105MZ9 stage II sporulation protein m BTG_28950 ENOG4105I3K Ferric uptake regulator, Fur family BTG_28960 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BTG_28985 ENOG4105D7N magnesium and cobalt transport protein CorA BTG_29025 ENOG4105DVE abc transporter atp-binding protein BTG_29030 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BTG_29035 ENOG4105DZ1 carboxypeptidase BTG_29040 ENOG41082AN stage II sporulation protein BTG_29050 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_29055 ENOG4105C8J )-transporter BTG_29075 ENOG41090VF Stage v sporulation protein ac BTG_29080 ENOG4105CZ3 stage V sporulation protein ad BTG_29090 ENOG4105G6R Stage v sporulation protein ae BTG_29100 ENOG4105J7I hydrolase BTG_29105 ENOG4105PTM secreted protein BTG_29110 ENOG4107ZE5 PPIases accelerate the folding of proteins BTG_29145 ENOG4105CE4 GlcNAc 6-P deacetylase BTG_29155 ENOG4105FDP GntR family transcriptional regulator BTG_29165 ENOG4105CID antiterminator BTG_29180 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BTG_29200 ENOG4105BZU Histidine kinase BTG_29210 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BTG_29225 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) BTG_29250 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BTG_29270 ENOG4105DTD Dehydrogenase BTG_29275 ENOG4105K7K Transcriptional regulator BTG_29305 ENOG4105CHU acetyl-coa acetyltransferase BTG_29345 ENOG4105CG3 alpha amylase, catalytic region BTG_29355 ENOG4107FKK extracellular solute-binding protein family 1 BTG_29365 ENOG4105EG2 ABC transporter, permease BTG_29370 ENOG4105FKQ transcriptional regulator BTG_29375 ENOG4105CHM Aminotransferase BTG_29385 ENOG4108HGU Histidine kinase BTG_29455 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BTG_29470 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BTG_29475 ENOG4105EPM Diguanylate phosphodiesterase BTG_29490 ENOG4107IN1 Protein of unknown function (DUF1797) BTG_29500 ENOG4108XRC Protein of unknown function (DUF458) BTG_29535 ENOG4107ZYR domain protein BTG_29540 ENOG4105CN5 Metallo-Beta-Lactamase BTG_29550 ENOG4108X4Q Hydrolase BTG_29555 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BTG_29570 ENOG4105CPP Dehydrogenase, E1 component BTG_29620 ENOG4105CXN decarboxylase BTG_29640 ENOG4105ECY inositol monophosphatase BTG_29650 ENOG4105CI3 gtp-binding protein typa BTG_29655 ENOG4105QA2 BTG_29675 ENOG4108IAB Phoh family BTG_29690 ENOG4105CNI cell division protein FtsW BTG_29695 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BTG_29745 ENOG4106UY4 Inherit from COG: Scp-like extracellular BTG_29760 ENOG4107TB6 phosphoglycerate mutase BTG_29780 ENOG4106H78 methyltransferase BTG_29790 ENOG4105H20 Sporulation integral membrane protein YlbJ BTG_29795 ENOG4105D78 K07001 NTE family protein BTG_29800 ENOG41063PX domain protein BTG_29810 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) BTG_29860 ENOG4108WRK Transcriptional regulator BTG_30025 ENOG4105CAR Terminase, large subunit BTG_30035 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BTG_30105 ENOG4105XSJ toxin secretion phage lysis holin BTG_30145 ENOG4105KNH Nucleic acid-binding protein BTG_30185 ENOG4105CJN penicillin-binding protein BTG_30190 ENOG4105CJN penicillin-binding protein BTG_30195 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BTG_30210 ENOG4105CNI cell division protein FtsW BTG_30215 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BTG_30220 ENOG4105D4A Cell wall formation (By similarity) BTG_30235 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BTG_30240 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BTG_30250 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BTG_30260 ENOG4105WR5 sporulation protein, YlmC YmxH family BTG_30265 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BTG_30270 ENOG4105DFA alanine racemase domain protein BTG_30280 ENOG41067XK integral membrane protein BTG_30285 ENOG4105DBK s4 domain protein BTG_30295 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BTG_30310 ENOG4105C34 Pseudouridine synthase BTG_30390 ENOG4105DC7 peptidase M24 BTG_30395 ENOG4105DC7 peptidase M24 BTG_30405 ENOG4105F23 Fibronectin-binding protein BTG_30415 ENOG4105DSJ YicC domain protein BTG_30435 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BTG_30440 ENOG4105C25 Primosomal protein n' BTG_30455 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BTG_30465 ENOG4108ZF3 Phosphatase BTG_30470 ENOG4105D9P serine threonine protein kinase BTG_30475 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BTG_30480 ENOG4105DJV ribulose-phosphate 3-epimerase BTG_30485 ENOG4105FJ0 thiamine BTG_30500 ENOG4108ZAA Alkaline-shock protein BTG_30505 ENOG4105DP4 dak2 domain fusion protein ylov BTG_30510 ENOG4105CB5 ATP-dependent DNA helicase recG BTG_30525 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BTG_30530 ENOG4105CHR reductase BTG_30943 ENOG4105DHF Membrane BTG_30963 ENOG4105K70 DNA-binding protein BTG_31008 ENOG4105KRN Transcriptional regulator, abrb family BTG_31028 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BTG_31038 ENOG4108J59 Extracellular solute-binding protein, family 5 BTG_31058 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BTG_31133 ENOG4105D9P serine threonine protein kinase BTG_31248 ENOG4105BZ1 (ABC) transporter BTG_31293 ENOG4105D7V transposase BTG_31523 ENOG4107QZI cell division protein FtsK BTG_31583 ENOG4105D7V transposase BTG_31683 ENOG4105CNU cell division protein FtsK BTG_31738 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BTG_31983 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BTG_32028 ENOG4108SHJ s-layer protein BTG_32033 ENOG4108SHJ s-layer protein BTG_32038 ENOG4108SHJ s-layer protein BTG_32063 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BTG_32078 ENOG4108ZHJ Organic hydroperoxide resistance protein BTG_32088 ENOG4105NA0 Transcriptional regulator BTG_32098 ENOG4105BZC d-serine deaminase BTG_32108 ENOG4108RCM Nitroreductase BTG_32113 ENOG4107V2S Transcriptional regulator BTG_32118 ENOG4105KVH Transcriptional regulator BTG_32128 ENOG4107V2S Transcriptional regulator BTG_32203 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BTG_32238 ENOG4108J59 Extracellular solute-binding protein, family 5 BTG_32253 ENOG4105K70 DNA-binding protein BTG_32258 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BTG_32288 ENOG4105DHF Membrane BTG_32573 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BTG_32578 ENOG4107S91 Sodium hydrogen exchanger BTG_32613 ENOG4108VB1 regulatoR BTG_32618 ENOG4106A7E Transcriptional regulator BTG_32658 ENOG4107S91 Sodium hydrogen exchanger BTG_32743 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BTG_32788 ENOG4106050 phage regulatory protein, rha family BTG_32833 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BTG_32843 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BTG_32878 ENOG4108N0N Phage Terminase Large Subunit BTG_33088 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BTG_33138 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BTG_33303 ENOG4105K4H Nlp p60 protein BTG_33318 ENOG4107QJE Chromosome Partitioning Protein BTG_33443 ENOG4108TFU terminase (Small subunit) BTG_33503 ENOG4107RHI Cytosine-specific methyltransferase