locus-tag	class	description
AS86_1	COG1196	nuclear chromosome segregation
AS86_100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS86_1001	COG0346	lactoylglutathione lyase activity
AS86_1002	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_1006	COG3655	Transcriptional regulator
AS86_1008	COG1785	Belongs to the alkaline phosphatase family
AS86_1009	COG2720	vancomycin resistance protein
AS86_101	COG0740	serine-type endopeptidase activity
AS86_1011	COG3239	Fatty acid desaturase
AS86_1015	COG0833	amino acid
AS86_1016	COG1414	Transcriptional regulator
AS86_1017	COG4187	Peptidase family M20/M25/M40
AS86_1018	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS86_1021	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_1024	COG2329	Antibiotic biosynthesis monooxygenase
AS86_1029	COG1070	Carbohydrate kinase
AS86_1030	COG2390	Transcriptional regulator
AS86_1032	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS86_1034	COG1879	ABC-type sugar transport system periplasmic component
AS86_104	COG2188	Transcriptional regulator
AS86_1041	COG1388	LysM domain
AS86_1041	COG3584	3D domain protein
AS86_1048	COG1605	Chorismate mutase
AS86_1048	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AS86_1051	COG0287	Prephenate dehydrogenase
AS86_1054	COG1309	transcriptional regulator
AS86_1055	COG1033	growth of symbiont in host cell
AS86_1055	COG2409	Drug exporters of the RND superfamily
AS86_1056	COG0488	(ABC) transporter
AS86_1057	COG1368	sulfuric ester hydrolase activity
AS86_1058	COG0861	Integral membrane protein TerC family
AS86_1062	COG0726	polysaccharide deacetylase
AS86_1064	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_1065	COG0346	lactoylglutathione lyase activity
AS86_1066	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS86_1067	COG4912	Dna alkylation repair
AS86_1071	COG2318	DinB family
AS86_1072	COG0697	spore germination
AS86_1074	COG2746	aminoglycoside 3-N-acetyltransferase activity
AS86_1080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS86_1081	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS86_1084	COG0628	permease
AS86_109	COG0612	Peptidase, M16
AS86_1094	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS86_1095	COG0436	Aminotransferase
AS86_110	COG0612	Peptidase, M16
AS86_1102	COG2226	methyltransferase
AS86_1105	COG2261	transglycosylase associated protein
AS86_1109	COG2814	Major facilitator Superfamily
AS86_1109	COG0477	Major facilitator Superfamily
AS86_111	COG0300	oxidoreductase activity
AS86_1110	COG4533	DNA binding
AS86_1111	COG0789	Transcriptional regulator
AS86_1112	COG1664	Polymer-forming cytoskeletal
AS86_1114	COG2814	Major facilitator Superfamily
AS86_1122	COG1307	EDD domain protein, DegV family
AS86_1123	COG1164	Oligoendopeptidase f
AS86_1128	COG0745	RESPONSE REGULATOR receiver
AS86_1129	COG5002	protein histidine kinase activity
AS86_1129	COG3850	Histidine kinase
AS86_1138	COG0667	Aldo Keto reductase
AS86_114	COG1426	Protein conserved in bacteria
AS86_1141	COG4948	Mandelate Racemase Muconate Lactonizing
AS86_1143	COG4166	transmembrane transport
AS86_1144	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS86_1146	COG0586	Pfam SNARE associated Golgi protein
AS86_115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AS86_1156	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS86_1157	COG3938	Belongs to the proline racemase family
AS86_1159	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AS86_1160	COG1012	belongs to the aldehyde dehydrogenase family
AS86_1161	COG1115	amino acid carrier protein
AS86_1162	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS86_1165	COG3397	chitin binding
AS86_1169	COG4637	Psort location Cytoplasmic, score
AS86_1176	COG0514	ATP-dependent DNA helicase (RecQ)
AS86_1179	COG3973	AAA domain
AS86_1180	COG0456	acetyltransferase
AS86_119	COG1692	metallophosphoesterase
AS86_1190	COG2315	Protein conserved in bacteria
AS86_1191	COG2267	carboxylic ester hydrolase activity
AS86_1191	COG2226	methyltransferase
AS86_1192	COG2205	protein histidine kinase activity
AS86_1194	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AS86_1196	COG1819	glycosyl
AS86_1197	COG3397	chitin binding
AS86_120	COG2359	stage V sporulation protein S
AS86_1201	COG2153	protein acetylation
AS86_1207	COG4175	Glycine betaine
AS86_1207	COG0517	IMP dehydrogenase activity
AS86_1208	COG4176	ABC-type proline glycine betaine transport system permease component
AS86_1215	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS86_1215	COG0456	acetyltransferase
AS86_1216	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_1219	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS86_122	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS86_122	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS86_1220	COG0022	dehydrogenase e1 component
AS86_1221	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS86_1222	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS86_1225	COG1959	2 iron, 2 sulfur cluster binding
AS86_1228	COG1349	DNA-binding transcription factor activity
AS86_123	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS86_1232	COG3284	Transcriptional regulator
AS86_1236	COG1309	transcriptional regulator
AS86_1243	COG3773	Cell wall hydrolase
AS86_1243	COG3409	Peptidoglycan-binding domain 1 protein
AS86_1244	COG2959	enzyme of heme biosynthesis
AS86_1247	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_125	COG4550	Control of competence regulator ComK, YlbF/YmcA
AS86_1255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_1256	COG0697	spore germination
AS86_1257	COG0201	protein transport
AS86_1258	COG0346	lactoylglutathione lyase activity
AS86_1261	COG0737	Belongs to the 5'-nucleotidase family
AS86_1262	COG3227	Zinc metalloprotease (Elastase)
AS86_1263	COG1523	belongs to the glycosyl hydrolase 13 family
AS86_1266	COG0076	glutamate decarboxylase activity
AS86_1268	COG1073	alpha beta
AS86_1269	COG0577	efflux transmembrane transporter activity
AS86_1270	COG1136	(ABC) transporter
AS86_1273	COG5002	protein histidine kinase activity
AS86_1274	COG0745	RESPONSE REGULATOR receiver
AS86_1280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS86_1283	COG1819	glycosyl
AS86_1284	COG1819	glycosyl
AS86_1292	COG0322	excinuclease ABC activity
AS86_130	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS86_1301	COG4667	esterase of the alpha-beta hydrolase superfamily
AS86_1305	COG3878	Protein conserved in bacteria
AS86_131	COG1368	sulfuric ester hydrolase activity
AS86_1310	COG1051	belongs to the nudix hydrolase family
AS86_1311	COG0592	DNA-directed DNA polymerase activity
AS86_1314	COG2223	nitrite transmembrane transporter activity
AS86_1318	COG0494	nUDIX hydrolase
AS86_1323	COG0697	spore germination
AS86_1324	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_1328	COG0584	glycerophosphoryl diester phosphodiesterase
AS86_133	COG3773	Cell wall hydrolase
AS86_1333	COG2814	Major facilitator Superfamily
AS86_134	COG1404	Belongs to the peptidase S8 family
AS86_1343	COG0671	phosphoesterase, PA-phosphatase related
AS86_1344	COG0604	alcohol dehydrogenase
AS86_135	COG0823	Involved in the tonB-independent uptake of proteins
AS86_1350	COG2169	Transcriptional regulator
AS86_136	COG0840	transmembrane signaling receptor activity
AS86_1363	COG2205	protein histidine kinase activity
AS86_1371	COG1533	DNA photolyase activity
AS86_1375	COG1090	epimerase
AS86_1377	COG2801	Transposase and inactivated derivatives
AS86_1379	COG2155	Conserved Protein
AS86_138	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_1381	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS86_1383	COG0415	Belongs to the DNA photolyase family
AS86_1385	COG2814	Major facilitator Superfamily
AS86_1387	COG0288	reversible hydration of carbon dioxide
AS86_1388	COG0640	Transcriptional regulator
AS86_1390	COG2918	glutathione biosynthetic process
AS86_1390	COG1181	Belongs to the D-alanine--D-alanine ligase family
AS86_1392	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AS86_1394	COG1733	regulation of RNA biosynthetic process
AS86_14	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AS86_140	COG1346	cytolysis
AS86_1405	COG1329	Transcriptional regulator
AS86_1408	COG0662	Cupin 2, conserved barrel domain protein
AS86_1419	COG1794	racemase activity, acting on amino acids and derivatives
AS86_1420	COG1819	glycosyl
AS86_1423	COG5002	protein histidine kinase activity
AS86_1424	COG0561	phosphatase activity
AS86_1431	COG2124	cytochrome p450
AS86_1442	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS86_1444	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_1449	COG0577	efflux transmembrane transporter activity
AS86_1450	COG1136	(ABC) transporter
AS86_1454	COG0667	Aldo Keto reductase
AS86_1455	COG0583	DNA-binding transcription factor activity
AS86_1456	COG2205	protein histidine kinase activity
AS86_1457	COG0745	RESPONSE REGULATOR receiver
AS86_1459	COG3773	Cell wall hydrolase
AS86_1460	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AS86_1462	COG3386	PFAM SMP-30 Gluconolaconase
AS86_1464	COG0693	protein deglycase activity
AS86_1467	COG2323	membrane
AS86_147	COG5001	Diguanylate cyclase
AS86_147	COG3300	MHYT domain
AS86_1472	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_148	COG2267	carboxylic ester hydrolase activity
AS86_1481	COG1733	regulation of RNA biosynthetic process
AS86_1482	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_1484	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS86_1490	COG2207	Transcriptional regulator
AS86_1491	COG3227	Zinc metalloprotease (Elastase)
AS86_1495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS86_15	COG0758	DNA mediated transformation
AS86_1501	COG1686	Belongs to the peptidase S11 family
AS86_1507	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS86_1508	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AS86_1509	COG1024	Enoyl-CoA hydratase
AS86_151	COG2364	Membrane
AS86_1510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AS86_1511	COG0511	ligase activity, forming carbon-carbon bonds
AS86_1512	COG0439	Biotin carboxylase
AS86_1513	COG1960	acyl-CoA dehydrogenase activity
AS86_1516	COG1309	transcriptional regulator
AS86_1521	COG1408	metallophosphoesterase
AS86_1524	COG2801	Transposase and inactivated derivatives
AS86_1528	COG1595	DNA-templated transcription, initiation
AS86_1529	COG0768	penicillin binding
AS86_153	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS86_1537	COG0726	polysaccharide deacetylase
AS86_1539	COG1396	sequence-specific DNA binding
AS86_154	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS86_1547	COG2814	Major facilitator Superfamily
AS86_1548	COG2234	aminopeptidase activity
AS86_155	COG2169	Transcriptional regulator
AS86_1550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS86_1553	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS86_1554	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS86_1555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS86_1557	COG0456	acetyltransferase
AS86_1559	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_156	COG0708	Exodeoxyribonuclease III
AS86_1560	COG0741	lytic transglycosylase activity
AS86_1568	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_157	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS86_1574	COG2814	Major facilitator Superfamily
AS86_1577	COG1686	Belongs to the peptidase S11 family
AS86_1579	COG0730	response to heat
AS86_158	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_1581	COG2002	toxin-antitoxin pair type II binding
AS86_1587	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS86_159	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_1594	COG3961	Belongs to the TPP enzyme family
AS86_1595	COG2226	methyltransferase
AS86_1597	COG3615	Tellurite resistance protein tehB
AS86_1597	COG0500	methyltransferase
AS86_16	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS86_160	COG1120	ATPase activity
AS86_1600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_1603	COG1846	Transcriptional regulator
AS86_1605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS86_1607	COG2971	BadF BadG BcrA BcrD
AS86_161	COG2819	hydrolase of the alpha beta superfamily
AS86_1612	COG1649	PFAM Uncharacterised BCR, COG1649
AS86_1617	COG1595	DNA-templated transcription, initiation
AS86_1618	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS86_1624	COG1396	sequence-specific DNA binding
AS86_1630	COG1132	(ABC) transporter
AS86_1631	COG1132	(ABC) transporter
AS86_1634	COG2258	MOSC domain
AS86_1635	COG0583	DNA-binding transcription factor activity
AS86_1637	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS86_1638	COG0583	DNA-binding transcription factor activity
AS86_1644	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_165	COG1937	Protein conserved in bacteria
AS86_1651	COG1247	-acetyltransferase
AS86_1658	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_166	COG2608	mercury ion transmembrane transporter activity
AS86_1662	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS86_167	COG2217	Heavy metal translocating P-type atpase
AS86_1670	COG1136	(ABC) transporter
AS86_1671	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS86_1672	COG1187	pseudouridine synthase activity
AS86_1676	COG1115	amino acid carrier protein
AS86_1678	COG2318	DinB family
AS86_1680	COG0776	regulation of translation
AS86_1683	COG2814	Major facilitator Superfamily
AS86_1684	COG3251	PFAM MbtH domain protein
AS86_1685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AS86_1686	COG3433	isochorismatase activity
AS86_1686	COG1535	isochorismatase
AS86_1687	COG1021	2,3-dihydroxybenzoate-AMP ligase
AS86_1688	COG1169	isochorismate synthase
AS86_1689	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_1690	COG2223	nitrite transmembrane transporter activity
AS86_1694	COG0419	ATPase involved in DNA repair
AS86_1695	COG0420	3'-5' exonuclease activity
AS86_1698	COG1024	Enoyl-CoA hydratase
AS86_1699	COG1280	lysine exporter protein (LysE YggA)
AS86_170	COG2116	formate transmembrane transporter activity
AS86_1701	COG2084	Dehydrogenase
AS86_1702	COG1960	acyl-CoA dehydrogenase activity
AS86_1703	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AS86_1704	COG2079	MmgE PrpD family protein
AS86_1705	COG0372	Belongs to the citrate synthase family
AS86_1706	COG4841	protein insertion into membrane
AS86_1707	COG2814	Major facilitator Superfamily
AS86_1709	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS86_1709	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS86_171	COG1408	metallophosphoesterase
AS86_1713	COG0300	oxidoreductase activity
AS86_1728	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS86_1729	COG0671	phosphoesterase, PA-phosphatase related
AS86_1730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS86_1732	COG3064	Membrane
AS86_1732	COG0515	serine threonine protein kinase
AS86_1732	COG4991	sh3 domain protein
AS86_1739	COG1509	lysine 2,3-aminomutase activity
AS86_174	COG1113	amino acid transport
AS86_1740	COG3829	transcription factor binding
AS86_1741	COG0456	acetyltransferase
AS86_1742	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS86_1743	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AS86_1744	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AS86_1745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS86_1748	COG5506	Protein of unknown function (DUF1694)
AS86_1749	COG1012	belongs to the aldehyde dehydrogenase family
AS86_1750	COG1253	flavin adenine dinucleotide binding
AS86_1757	COG1174	glycine betaine transport
AS86_1758	COG1125	glycine betaine transport
AS86_1758	COG0517	IMP dehydrogenase activity
AS86_1765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS86_177	COG2322	membrane
AS86_1771	COG1064	alcohol dehydrogenase
AS86_1772	COG0384	phenazine biosynthesis protein PhzF
AS86_1773	COG1737	Transcriptional regulator
AS86_1774	COG2197	response regulator
AS86_1775	COG2203	Gaf domain
AS86_1775	COG4585	Histidine kinase
AS86_1776	COG0668	transmembrane transport
AS86_1777	COG1051	belongs to the nudix hydrolase family
AS86_1778	COG1335	isochorismatase
AS86_178	COG1979	alcohol dehydrogenase
AS86_1781	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS86_1782	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS86_1783	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS86_1786	COG0367	asparagine synthase
AS86_1787	COG0071	Belongs to the small heat shock protein (HSP20) family
AS86_1788	COG1999	signal sequence binding
AS86_179	COG1349	DNA-binding transcription factor activity
AS86_1790	COG1307	EDD domain protein, DegV family
AS86_1792	COG0805	protein transport
AS86_1794	COG1272	protein, Hemolysin III
AS86_1795	COG0204	Acyl-transferase
AS86_1797	COG0768	penicillin binding
AS86_18	COG4974	Belongs to the 'phage' integrase family
AS86_180	COG1105	Belongs to the carbohydrate kinase PfkB family
AS86_1803	COG0546	phosphoglycolate phosphatase activity
AS86_1806	COG1131	(ABC) transporter
AS86_1808	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AS86_1809	COG3655	Transcriptional regulator
AS86_181	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS86_181	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS86_181	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS86_1810	COG0456	acetyltransferase
AS86_1812	COG1794	racemase activity, acting on amino acids and derivatives
AS86_1814	COG2610	gluconate transmembrane transporter activity
AS86_1819	COG0733	neurotransmitter:sodium symporter activity
AS86_182	COG1388	LysM domain
AS86_182	COG3584	3D domain protein
AS86_1820	COG0017	Asparaginyl-tRNA synthetase
AS86_1828	COG0018	arginyl-trna synthetase
AS86_1829	COG2521	methyltransferase
AS86_1829	COG2136	Putative SAM-dependent methyltransferase
AS86_1832	COG1413	lyase activity
AS86_1834	COG0629	single-stranded DNA binding
AS86_1837	COG0488	(ABC) transporter
AS86_1838	COG1418	mRNA catabolic process
AS86_1841	COG0457	Tetratricopeptide repeat
AS86_1845	COG2359	stage V sporulation protein S
AS86_1852	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AS86_1853	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS86_1854	COG2146	nitrite reductase [NAD(P)H] activity
AS86_1855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AS86_1855	COG1587	Uroporphyrinogen-III synthase
AS86_1856	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AS86_1857	COG1648	precorrin-2 dehydrogenase activity
AS86_1860	COG2223	nitrite transmembrane transporter activity
AS86_1862	COG0314	molybdopterin synthase activity
AS86_1863	COG0303	'Molybdopterin
AS86_1864	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS86_1865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS86_1866	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS86_1867	COG2181	nitrate reductase activity
AS86_1868	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AS86_1869	COG1140	nitrate reductase beta subunit
AS86_1870	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AS86_1871	COG0714	Associated with various cellular activities
AS86_1872	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AS86_1873	COG1305	Transglutaminase-like
AS86_1874	COG0386	Belongs to the glutathione peroxidase family
AS86_1876	COG0426	domain, Protein
AS86_1876	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS86_1878	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AS86_188	COG0464	growth
AS86_1880	COG1595	DNA-templated transcription, initiation
AS86_1881	COG0604	alcohol dehydrogenase
AS86_1883	COG0346	lactoylglutathione lyase activity
AS86_1884	COG1082	Xylose isomerase domain protein TIM barrel
AS86_1888	COG2226	methyltransferase
AS86_1893	COG3874	Sporulation protein YtfJ
AS86_1895	COG4974	Belongs to the 'phage' integrase family
AS86_190	COG2860	membrane
AS86_191	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS86_192	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AS86_1928	COG0456	acetyltransferase
AS86_193	COG0789	Transcriptional regulator
AS86_1934	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_1935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_1936	COG1819	glycosyl
AS86_194	COG0174	glutamine synthetase
AS86_1940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS86_1942	COG2814	Major facilitator Superfamily
AS86_1943	COG1846	Transcriptional regulator
AS86_1944	COG0561	phosphatase activity
AS86_1946	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS86_1949	COG2211	Major facilitator Superfamily
AS86_1952	COG1876	peptidase activity
AS86_1954	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS86_1957	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS86_1958	COG1114	Component of the transport system for branched-chain amino acids
AS86_1963	COG1253	flavin adenine dinucleotide binding
AS86_1964	COG2839	Protein conserved in bacteria
AS86_1965	COG0702	epimerase
AS86_1968	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS86_1969	COG1607	acyl-coa hydrolase
AS86_1970	COG3689	TIGRFAM TIGR03943 family protein
AS86_1971	COG0701	Predicted permease
AS86_1973	COG2244	polysaccharide biosynthetic process
AS86_1974	COG0586	Pfam SNARE associated Golgi protein
AS86_1975	COG1051	belongs to the nudix hydrolase family
AS86_1976	COG5337	Spore coat protein CotH
AS86_1978	COG0406	alpha-ribazole phosphatase activity
AS86_1981	COG4166	transmembrane transport
AS86_1983	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS86_1985	COG0702	epimerase
AS86_1987	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS86_1988	COG0456	acetyltransferase
AS86_1989	COG0523	cobalamin synthesis protein
AS86_1990	COG4989	oxidoreductase activity
AS86_1991	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_1992	COG1231	oxidoreductase activity
AS86_1994	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS86_1997	COG0783	Belongs to the Dps family
AS86_1998	COG3949	Membrane
AS86_2	COG0552	protein localization to endoplasmic reticulum
AS86_2001	COG0840	transmembrane signaling receptor activity
AS86_2007	COG0667	Aldo Keto reductase
AS86_2008	COG0640	Transcriptional regulator
AS86_2009	COG1404	Belongs to the peptidase S8 family
AS86_2010	COG2002	toxin-antitoxin pair type II binding
AS86_2011	COG0577	efflux transmembrane transporter activity
AS86_2012	COG0577	efflux transmembrane transporter activity
AS86_2018	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS86_202	COG0741	lytic transglycosylase activity
AS86_2020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_2021	COG1279	arginine transmembrane transporter activity
AS86_2022	COG2814	Major facilitator Superfamily
AS86_2024	COG1082	Xylose isomerase domain protein TIM barrel
AS86_2027	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_2028	COG4264	IucA IucC family
AS86_203	COG1196	nuclear chromosome segregation
AS86_203	COG0741	lytic transglycosylase activity
AS86_203	COG0739	heme binding
AS86_2030	COG1247	-acetyltransferase
AS86_2031	COG1285	pathogenesis
AS86_2033	COG0726	polysaccharide deacetylase
AS86_2034	COG1316	TRANSCRIPTIONal
AS86_2039	COG0460	homoserine dehydrogenase
AS86_2043	COG0726	polysaccharide deacetylase
AS86_2047	COG0300	oxidoreductase activity
AS86_2048	COG5002	protein histidine kinase activity
AS86_2049	COG0745	RESPONSE REGULATOR receiver
AS86_205	COG1695	Transcriptional regulator
AS86_2050	COG1132	(ABC) transporter
AS86_2052	COG1388	LysM domain
AS86_2052	COG0791	NLP P60 protein
AS86_2055	COG1686	Belongs to the peptidase S11 family
AS86_2063	COG1216	Glycosyl transferase, family 2
AS86_2065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AS86_2066	COG4988	ABC transporter
AS86_2067	COG1294	oxidase, subunit
AS86_2068	COG1271	oxidase subunit
AS86_2075	COG0583	DNA-binding transcription factor activity
AS86_2077	COG0559	Belongs to the binding-protein-dependent transport system permease family
AS86_2079	COG0411	ABC transporter
AS86_2081	COG0523	cobalamin synthesis protein
AS86_2082	COG1231	oxidoreductase activity
AS86_2084	COG0628	permease
AS86_2087	COG0778	Nitroreductase
AS86_2088	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS86_2089	COG1959	2 iron, 2 sulfur cluster binding
AS86_209	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS86_2090	COG0583	DNA-binding transcription factor activity
AS86_2091	COG0697	spore germination
AS86_2092	COG4549	nuclear export factor GLE1
AS86_2093	COG1276	copper resistance
AS86_2093	COG2372	response to copper ion
AS86_2095	COG1114	Component of the transport system for branched-chain amino acids
AS86_2102	COG2132	Multicopper oxidase
AS86_2104	COG0006	proline dipeptidase activity
AS86_2106	COG4846	Membrane protein involved in cytochrome C biogenesis
AS86_211	COG0737	Belongs to the 5'-nucleotidase family
AS86_2114	COG0295	cytidine deaminase activity
AS86_2115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AS86_2116	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_2118	COG2390	Transcriptional regulator
AS86_2119	COG1309	transcriptional regulator
AS86_212	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS86_2122	COG0456	acetyltransferase
AS86_2125	COG2309	aminopeptidase activity
AS86_2129	COG0531	amino acid
AS86_2131	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS86_2135	COG1914	H( )-stimulated, divalent metal cation uptake system
AS86_2139	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_2140	COG4166	transmembrane transport
AS86_2144	COG0427	acetyl-CoA hydrolase
AS86_2145	COG3279	Response regulator of the LytR AlgR family
AS86_2148	COG3384	dioxygenase
AS86_2149	COG2814	Major facilitator Superfamily
AS86_2154	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AS86_2158	COG0028	Belongs to the TPP enzyme family
AS86_2159	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS86_2161	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS86_2165	COG2323	membrane
AS86_2166	COG5566	PFAM Mor transcription activator
AS86_2168	COG0733	neurotransmitter:sodium symporter activity
AS86_2172	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS86_2173	COG2223	nitrite transmembrane transporter activity
AS86_2174	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS86_2176	COG0477	Major facilitator Superfamily
AS86_2178	COG1695	Transcriptional regulator
AS86_2181	COG2814	Major facilitator Superfamily
AS86_219	COG1132	(ABC) transporter
AS86_2190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS86_2191	COG0784	Response regulator, receiver
AS86_2192	COG4191	Histidine kinase
AS86_2193	COG0281	malic enzyme
AS86_2194	COG1027	Aspartate ammonia-lyase
AS86_2196	COG0528	UMP kinase activity
AS86_2197	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS86_220	COG1132	(ABC) transporter
AS86_2200	COG1131	(ABC) transporter
AS86_2207	COG2733	membrane
AS86_2210	COG0457	Tetratricopeptide repeat
AS86_2213	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS86_2214	COG0785	Cytochrome C biogenesis protein
AS86_2218	COG3340	Belongs to the peptidase S51 family
AS86_2219	COG0534	Mate efflux family protein
AS86_2225	COG0789	Transcriptional regulator
AS86_2226	COG1757	Na H antiporter
AS86_2227	COG0438	transferase activity, transferring glycosyl groups
AS86_2227	COG1216	Glycosyl transferase, family 2
AS86_2229	COG0701	Predicted permease
AS86_2230	COG0523	cobalamin synthesis protein
AS86_2237	COG0367	asparagine synthase
AS86_2239	COG1846	Transcriptional regulator
AS86_2243	COG0406	alpha-ribazole phosphatase activity
AS86_2249	COG1234	tRNA 3'-trailer cleavage
AS86_225	COG0730	response to heat
AS86_2250	COG1177	transmembrane transport
AS86_2252	COG3842	ATPase activity
AS86_2258	COG1215	transferase activity, transferring glycosyl groups
AS86_2259	COG2329	Antibiotic biosynthesis monooxygenase
AS86_2265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS86_2267	COG4786	Flagellar basal body rod
AS86_2268	COG1419	protein localization to endoplasmic reticulum
AS86_2269	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS86_2270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AS86_2272	COG1987	bacterial-type flagellum assembly
AS86_2273	COG1338	Plays a role in the flagellum-specific transport system
AS86_2275	COG1776	CheC inhibitor of MCP methylation
AS86_2275	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS86_2276	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS86_2278	COG0741	lytic transglycosylase activity
AS86_2279	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS86_228	COG1346	cytolysis
AS86_2285	COG0835	chemotaxis
AS86_2285	COG0784	Response regulator, receiver
AS86_2288	COG1749	Flagellar hook protein flgE
AS86_2292	COG1157	protein secretion by the type III secretion system
AS86_2294	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS86_2295	COG1766	The M ring may be actively involved in energy transduction
AS86_2296	COG1677	Flagellar hook-basal body complex protein FliE
AS86_2297	COG1558	bacterial-type flagellum-dependent cell motility
AS86_2298	COG1815	bacterial-type flagellum-dependent cell motility
AS86_230	COG0583	DNA-binding transcription factor activity
AS86_2302	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AS86_2303	COG1256	bacterial-type flagellum assembly
AS86_2307	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS86_2310	COG1776	CheC inhibitor of MCP methylation
AS86_2310	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AS86_2311	COG2198	Histidine kinase
AS86_2311	COG0643	Histidine kinase
AS86_2312	COG2201	protein-glutamate methylesterase activity
AS86_2313	COG1360	Flagellar Motor Protein
AS86_2314	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS86_2316	COG1923	regulation of RNA biosynthetic process
AS86_2323	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AS86_2324	COG2323	membrane
AS86_2326	COG0789	Transcriptional regulator
AS86_2326	COG4978	Transcriptional regulator
AS86_2329	COG0475	glutathione-regulated potassium exporter activity
AS86_2331	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS86_2332	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS86_2336	COG1280	lysine exporter protein (LysE YggA)
AS86_2337	COG3403	YqcI/YcgG family
AS86_234	COG1131	(ABC) transporter
AS86_2344	COG0328	RNA-DNA hybrid ribonuclease activity
AS86_2348	COG0454	-acetyltransferase
AS86_2351	COG0438	transferase activity, transferring glycosyl groups
AS86_2352	COG1215	transferase activity, transferring glycosyl groups
AS86_2355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS86_2357	COG3944	biosynthesis protein
AS86_2360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS86_2363	COG0754	glutathionylspermidine amidase activity
AS86_2368	COG0456	acetyltransferase
AS86_2370	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS86_2371	COG2311	Membrane
AS86_2372	COG2233	PERMEase
AS86_2374	COG0024	Methionine aminopeptidase
AS86_2375	COG3173	Aminoglycoside phosphotransferase
AS86_2377	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AS86_2378	COG1199	ATP-dependent helicase activity
AS86_238	COG0785	Cytochrome C biogenesis protein
AS86_2380	COG0116	Belongs to the methyltransferase superfamily
AS86_239	COG4846	Membrane protein involved in cytochrome C biogenesis
AS86_2391	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS86_2391	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS86_2393	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS86_2394	COG3935	DnaD domain protein
AS86_2398	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AS86_2398	COG1199	ATP-dependent helicase activity
AS86_2405	COG0438	transferase activity, transferring glycosyl groups
AS86_2409	COG1694	Mazg nucleotide pyrophosphohydrolase
AS86_2410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_2412	COG2738	Putative neutral zinc metallopeptidase
AS86_2415	COG4347	Protein of unknown function (DUF1405)
AS86_2416	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS86_2416	COG2010	Cytochrome c
AS86_2417	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AS86_2421	COG0457	Tetratricopeptide repeat
AS86_2426	COG0142	geranyltranstransferase activity
AS86_2428	COG0142	geranyltranstransferase activity
AS86_2431	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS86_2445	COG0252	asparaginase activity
AS86_2446	COG0492	ferredoxin-NADP+ reductase activity
AS86_2450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS86_2452	COG0789	Transcriptional regulator
AS86_2453	COG1408	metallophosphoesterase
AS86_2455	COG1266	CAAX protease self-immunity
AS86_2456	COG0514	ATP-dependent DNA helicase (RecQ)
AS86_2458	COG1141	Ferredoxin
AS86_2459	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AS86_2461	COG4942	peptidase
AS86_2462	COG2096	Adenosyltransferase
AS86_2463	COG5002	protein histidine kinase activity
AS86_2464	COG0745	RESPONSE REGULATOR receiver
AS86_2465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS86_2466	COG1333	cytochrome c biogenesis protein
AS86_2468	COG1187	pseudouridine synthase activity
AS86_2469	COG0700	Nucleoside recognition
AS86_2470	COG2715	membrane protein required for spore maturation
AS86_2471	COG1686	Belongs to the peptidase S11 family
AS86_2472	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS86_2475	COG0392	lysyltransferase activity
AS86_2475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AS86_2478	COG5002	protein histidine kinase activity
AS86_2479	COG0582	viral genome integration into host DNA
AS86_2481	COG1801	Protein of unknown function DUF72
AS86_2482	COG3852	Histidine kinase
AS86_2485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS86_2486	COG1392	Phosphate transport regulator
AS86_2487	COG0306	phosphate transporter
AS86_2488	COG0730	response to heat
AS86_249	COG0010	Belongs to the arginase family
AS86_2498	COG1114	Component of the transport system for branched-chain amino acids
AS86_250	COG1329	Transcriptional regulator
AS86_2500	COG2197	response regulator
AS86_2501	COG4585	Histidine kinase
AS86_2502	COG4758	membrane
AS86_2505	COG1757	Na H antiporter
AS86_251	COG1902	pentaerythritol trinitrate reductase activity
AS86_2510	COG0733	neurotransmitter:sodium symporter activity
AS86_2511	COG1648	precorrin-2 dehydrogenase activity
AS86_2515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS86_2516	COG0529	Catalyzes the synthesis of activated sulfate
AS86_252	COG0069	glutamate synthase activity
AS86_2520	COG0019	diaminopimelate decarboxylase activity
AS86_2522	COG1368	sulfuric ester hydrolase activity
AS86_2523	COG1183	phosphatidylcholine synthase activity
AS86_2526	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS86_254	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS86_2541	COG0440	acetolactate synthase activity
AS86_2542	COG0028	Belongs to the TPP enzyme family
AS86_2543	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS86_2547	COG3874	Sporulation protein YtfJ
AS86_2548	COG4709	membrane
AS86_2549	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS86_255	COG0346	lactoylglutathione lyase activity
AS86_2550	COG1301	dicarboxylic acid transport
AS86_2552	COG1846	Transcriptional regulator
AS86_256	COG0400	carboxylic ester hydrolase activity
AS86_2563	COG0716	FMN binding
AS86_2568	COG1696	Membrane protein involved in D-alanine export
AS86_257	COG5002	protein histidine kinase activity
AS86_2570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS86_2571	COG2070	2-Nitropropane dioxygenase
AS86_2572	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS86_2574	COG1335	isochorismatase
AS86_2576	COG1522	sequence-specific DNA binding
AS86_2580	COG1131	(ABC) transporter
AS86_2582	COG1131	(ABC) transporter
AS86_2583	COG1725	Transcriptional regulator
AS86_2584	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS86_2585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS86_2586	COG1780	Probably involved in ribonucleotide reductase function
AS86_259	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_2592	COG4873	Protein conserved in bacteria
AS86_2595	COG0720	synthase
AS86_2597	COG5002	protein histidine kinase activity
AS86_2599	COG2318	DinB family
AS86_2601	COG1846	Transcriptional regulator
AS86_2602	COG3852	Histidine kinase
AS86_2604	COG2861	carbohydrate metabolic process
AS86_2606	COG0235	Class ii aldolase
AS86_2609	COG1349	DNA-binding transcription factor activity
AS86_2614	COG3842	ATPase activity
AS86_2615	COG1840	ABC-type Fe3 transport system, periplasmic component
AS86_2618	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS86_2620	COG3243	poly(R)-hydroxyalkanoic acid synthase
AS86_2621	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_2625	COG2030	dehydratase
AS86_2627	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS86_2628	COG0861	Integral membrane protein TerC family
AS86_2629	COG2116	formate transmembrane transporter activity
AS86_2631	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS86_2635	COG2186	Transcriptional regulator
AS86_2636	COG5002	protein histidine kinase activity
AS86_2637	COG0745	RESPONSE REGULATOR receiver
AS86_2639	COG3835	regulator
AS86_2640	COG0277	FAD linked oxidase domain protein
AS86_2641	COG0247	lactate metabolic process
AS86_2642	COG2340	Cysteine-rich secretory protein family
AS86_2644	COG0564	pseudouridine synthase activity
AS86_2646	COG2409	Drug exporters of the RND superfamily
AS86_2647	COG0671	phosphoesterase, PA-phosphatase related
AS86_2648	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AS86_2649	COG1177	transmembrane transport
AS86_2650	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS86_2652	COG1012	belongs to the aldehyde dehydrogenase family
AS86_2659	COG0681	Belongs to the peptidase S26 family
AS86_266	COG1396	sequence-specific DNA binding
AS86_2660	COG1686	Belongs to the peptidase S11 family
AS86_2662	COG2226	methyltransferase
AS86_2666	COG2801	Transposase and inactivated derivatives
AS86_2668	COG1668	transmembrane transport
AS86_2669	COG4152	abc transporter atp-binding protein
AS86_267	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_2674	COG1476	TRANSCRIPTIONal
AS86_2676	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS86_268	COG1268	BioY protein
AS86_2687	COG5634	Uncharacterized conserved protein (DUF2278)
AS86_2688	COG1620	l-lactate permease
AS86_269	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_2695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS86_2695	COG0512	Glutamine amidotransferase of anthranilate synthase
AS86_2697	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS86_2698	COG5492	domain, Protein
AS86_27	COG4589	Belongs to the CDS family
AS86_270	COG0183	Belongs to the thiolase family
AS86_2701	COG2382	esterase
AS86_2703	COG2153	protein acetylation
AS86_2711	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS86_2714	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AS86_2723	COG1216	Glycosyl transferase, family 2
AS86_2724	COG0772	Belongs to the SEDS family
AS86_2727	COG0564	pseudouridine synthase activity
AS86_2729	COG2357	RelA SpoT domain protein
AS86_273	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AS86_2731	COG4116	CYTH
AS86_2732	COG2346	COG2346, Truncated hemoglobins
AS86_2734	COG1164	Oligoendopeptidase f
AS86_2736	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS86_2738	COG0861	Integral membrane protein TerC family
AS86_2739	COG1393	Belongs to the ArsC family
AS86_2741	COG4166	transmembrane transport
AS86_2742	COG0534	Mate efflux family protein
AS86_2743	COG4608	Belongs to the ABC transporter superfamily
AS86_2744	COG0444	Belongs to the ABC transporter superfamily
AS86_2745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS86_2746	COG0601	transmembrane transport
AS86_2747	COG4166	transmembrane transport
AS86_2749	COG0180	Tryptophanyl-tRNA synthetase
AS86_275	COG2211	Major facilitator Superfamily
AS86_2751	COG5504	Zn-dependent protease
AS86_2752	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS86_2753	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS86_2756	COG2267	carboxylic ester hydrolase activity
AS86_2760	COG0561	phosphatase activity
AS86_2763	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_2775	COG3209	COG3209 Rhs family protein
AS86_2776	COG2996	Protein conserved in bacteria
AS86_2780	COG0004	ammonium transporteR
AS86_2781	COG0753	catalase activity
AS86_2783	COG0367	asparagine synthase
AS86_2788	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS86_279	COG0726	polysaccharide deacetylase
AS86_2800	COG0398	Pfam SNARE associated Golgi protein
AS86_2801	COG4903	ComK protein
AS86_2804	COG1278	Cold shock
AS86_2807	COG2224	Isocitrate lyase
AS86_2808	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AS86_281	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AS86_2810	COG3693	PFAM glycoside hydrolase, family 10
AS86_2812	COG0840	transmembrane signaling receptor activity
AS86_2813	COG0501	Belongs to the peptidase M48B family
AS86_2817	COG0745	RESPONSE REGULATOR receiver
AS86_2818	COG2205	protein histidine kinase activity
AS86_282	COG1122	ATPase activity
AS86_2820	COG2207	Transcriptional regulator
AS86_2820	COG3708	Transcriptional regulator
AS86_2821	COG1595	DNA-templated transcription, initiation
AS86_2823	COG1078	dGTPase activity
AS86_2824	COG1408	metallophosphoesterase
AS86_2825	COG1073	alpha beta
AS86_2838	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_284	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS86_2840	COG0095	Lipoate-protein ligase
AS86_2841	COG1234	tRNA 3'-trailer cleavage
AS86_2843	COG1609	Transcriptional regulator
AS86_2848	COG1511	domain protein
AS86_2849	COG1309	transcriptional regulator
AS86_2857	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS86_2858	COG2329	Antibiotic biosynthesis monooxygenase
AS86_2859	COG3428	Bacterial PH domain
AS86_2860	COG3402	PFAM membrane-flanked domain
AS86_2861	COG0697	spore germination
AS86_2868	COG3428	Bacterial PH domain
AS86_2869	COG3402	PFAM membrane-flanked domain
AS86_2871	COG1309	transcriptional regulator
AS86_2873	COG4473	ABC transporter
AS86_2874	COG1131	(ABC) transporter
AS86_2875	COG0537	adenosine 5'-monophosphoramidase activity
AS86_2876	COG4980	gas vesicle protein
AS86_2881	COG3973	AAA domain
AS86_2888	COG1695	Transcriptional regulator
AS86_2889	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AS86_289	COG0824	Thioesterase
AS86_2891	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS86_2892	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS86_2894	COG3620	sequence-specific DNA binding
AS86_2895	COG2140	Oxalate decarboxylase
AS86_29	COG0750	zinc metalloprotease
AS86_290	COG4841	protein insertion into membrane
AS86_2900	COG2267	carboxylic ester hydrolase activity
AS86_2903	COG0346	lactoylglutathione lyase activity
AS86_2904	COG0346	lactoylglutathione lyase activity
AS86_2905	COG1280	lysine exporter protein (LysE YggA)
AS86_2908	COG4717	serine-type aminopeptidase activity
AS86_2909	COG0420	3'-5' exonuclease activity
AS86_2913	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AS86_2923	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AS86_2924	COG2208	phosphoserine phosphatase activity
AS86_2926	COG1191	sigma factor activity
AS86_2939	COG2373	Large extracellular alpha-helical protein
AS86_294	COG0745	RESPONSE REGULATOR receiver
AS86_295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS86_2952	COG2376	Dihydroxyacetone kinase
AS86_2954	COG2376	Dihydroxyacetone kinase
AS86_2956	COG0640	Transcriptional regulator
AS86_2957	COG2814	Major facilitator Superfamily
AS86_2959	COG1183	phosphatidylcholine synthase activity
AS86_296	COG1832	CoA-binding protein
AS86_297	COG0187	DNA topoisomerase II activity
AS86_2970	COG1073	alpha beta
AS86_298	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS86_2985	COG0477	Major facilitator Superfamily
AS86_299	COG0673	inositol 2-dehydrogenase activity
AS86_2990	COG0305	Participates in initiation and elongation during chromosome replication
AS86_2994	COG0210	DNA helicase
AS86_3002	COG3181	Tripartite tricarboxylate transporter family receptor
AS86_3003	COG4565	transcriptional regulatory protein
AS86_3004	COG3290	protein histidine kinase activity
AS86_3005	COG0477	Major facilitator Superfamily
AS86_3013	COG3157	Type VI secretion system effector, Hcp
AS86_3020	COG2801	Transposase and inactivated derivatives
AS86_3027	COG2814	Major facilitator Superfamily
AS86_3028	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS86_303	COG1131	(ABC) transporter
AS86_3031	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS86_3036	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_3038	COG4608	Belongs to the ABC transporter superfamily
AS86_3039	COG0444	Belongs to the ABC transporter superfamily
AS86_3040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS86_3041	COG0601	transmembrane transport
AS86_3048	COG1363	Peptidase, m42
AS86_305	COG1595	DNA-templated transcription, initiation
AS86_3052	COG1024	Enoyl-CoA hydratase
AS86_3056	COG2244	polysaccharide biosynthetic process
AS86_3057	COG0659	secondary active sulfate transmembrane transporter activity
AS86_3059	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_3060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS86_3061	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_3061	COG3409	Peptidoglycan-binding domain 1 protein
AS86_3063	COG0561	phosphatase activity
AS86_3066	COG3527	Alpha-acetolactate decarboxylase
AS86_3067	COG0028	Belongs to the TPP enzyme family
AS86_307	COG1316	TRANSCRIPTIONal
AS86_3073	COG0189	ligase activity
AS86_3076	COG1126	abc transporter atp-binding protein
AS86_3077	COG0765	amino acid transport
AS86_3078	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS86_3079	COG1132	(ABC) transporter
AS86_308	COG1301	dicarboxylic acid transport
AS86_3080	COG1132	(ABC) transporter
AS86_3081	COG1012	belongs to the aldehyde dehydrogenase family
AS86_3082	COG0531	amino acid
AS86_3084	COG0693	protein deglycase activity
AS86_3084	COG0753	catalase activity
AS86_3085	COG0693	protein deglycase activity
AS86_3089	COG1733	regulation of RNA biosynthetic process
AS86_309	COG4166	transmembrane transport
AS86_3090	COG2814	Major facilitator Superfamily
AS86_3091	COG1309	transcriptional regulator
AS86_3093	COG2076	Multidrug Resistance protein
AS86_3094	COG0789	Transcriptional regulator
AS86_3095	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_3097	COG1522	sequence-specific DNA binding
AS86_3101	COG2259	Doxx family
AS86_3103	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS86_3103	COG1263	PTS System
AS86_3105	COG1737	Transcriptional regulator
AS86_3107	COG0475	glutathione-regulated potassium exporter activity
AS86_3108	COG0531	amino acid
AS86_311	COG4166	transmembrane transport
AS86_3115	COG0586	Pfam SNARE associated Golgi protein
AS86_312	COG4166	transmembrane transport
AS86_3122	COG3546	catalase activity
AS86_3123	COG1114	Component of the transport system for branched-chain amino acids
AS86_3126	COG5522	Integral membrane protein (intg_mem_TP0381)
AS86_3128	COG1136	(ABC) transporter
AS86_3129	COG0577	efflux transmembrane transporter activity
AS86_313	COG2226	methyltransferase
AS86_3130	COG1388	LysM domain
AS86_3130	COG3584	3D domain protein
AS86_3135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS86_3136	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS86_3137	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS86_3137	COG3711	transcriptional antiterminator
AS86_3140	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS86_3141	COG0604	alcohol dehydrogenase
AS86_3142	COG1316	TRANSCRIPTIONal
AS86_3144	COG0730	response to heat
AS86_3145	COG2210	Belongs to the sulfur carrier protein TusA family
AS86_3147	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS86_3147	COG0425	Belongs to the sulfur carrier protein TusA family
AS86_3148	COG0425	Belongs to the sulfur carrier protein TusA family
AS86_3149	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_3149	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS86_3150	COG0425	Belongs to the sulfur carrier protein TusA family
AS86_3150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS86_3151	COG1937	Protein conserved in bacteria
AS86_3153	COG3591	Belongs to the peptidase S1B family
AS86_3156	COG2719	SpoVR family
AS86_3157	COG0778	Nitroreductase
AS86_3169	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_3170	COG2252	PERMEase
AS86_3173	COG1846	Transcriptional regulator
AS86_3174	COG2814	Major facilitator Superfamily
AS86_3175	COG2205	protein histidine kinase activity
AS86_3182	COG0351	phosphomethylpyrimidine kinase
AS86_3183	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS86_3185	COG2104	thiamine diphosphate biosynthetic process
AS86_3186	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS86_3187	COG0352	thiamine-phosphate diphosphorylase activity
AS86_3188	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS86_3189	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS86_3190	COG1116	anion transmembrane transporter activity
AS86_3191	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AS86_3195	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AS86_322	COG0697	spore germination
AS86_3222	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS86_3224	COG0581	inorganic phosphate transmembrane transporter activity
AS86_3225	COG0573	inorganic phosphate transmembrane transporter activity
AS86_3226	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AS86_3227	COG1918	ferrous iron import across plasma membrane
AS86_3227	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS86_3228	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS86_3229	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AS86_3231	COG0531	amino acid
AS86_3232	COG0697	spore germination
AS86_3233	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS86_3236	COG4990	cell redox homeostasis
AS86_3237	COG0833	amino acid
AS86_3238	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AS86_3239	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AS86_3242	COG0569	domain protein
AS86_3242	COG0475	glutathione-regulated potassium exporter activity
AS86_3244	COG2153	protein acetylation
AS86_3247	COG2252	PERMEase
AS86_3248	COG1113	amino acid transport
AS86_325	COG3383	formate dehydrogenase (NAD+) activity
AS86_3251	COG1114	Component of the transport system for branched-chain amino acids
AS86_3253	COG3104	oligopeptide transport
AS86_3257	COG1476	TRANSCRIPTIONal
AS86_3258	COG3583	domain protein
AS86_3258	COG3584	3D domain protein
AS86_3259	COG0840	transmembrane signaling receptor activity
AS86_3268	COG1063	alcohol dehydrogenase
AS86_3273	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS86_3274	COG1879	ABC-type sugar transport system periplasmic component
AS86_3275	COG1172	Belongs to the binding-protein-dependent transport system permease family
AS86_3278	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS86_3279	COG1609	Transcriptional regulator
AS86_3280	COG0477	Major facilitator Superfamily
AS86_3281	COG1846	Transcriptional regulator
AS86_3282	COG2271	Major facilitator Superfamily
AS86_3285	COG0659	secondary active sulfate transmembrane transporter activity
AS86_3290	COG5002	protein histidine kinase activity
AS86_3291	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS86_3292	COG2378	regulation of single-species biofilm formation
AS86_3294	COG1595	DNA-templated transcription, initiation
AS86_3297	COG0833	amino acid
AS86_3298	COG0765	amino acid transport
AS86_3299	COG0765	amino acid transport
AS86_33	COG0195	Participates in both transcription termination and antitermination
AS86_3300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS86_3301	COG1126	abc transporter atp-binding protein
AS86_3302	COG1115	amino acid carrier protein
AS86_3303	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS86_3304	COG0697	spore germination
AS86_3308	COG0366	Alpha amylase catalytic
AS86_3309	COG1263	PTS System
AS86_3309	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS86_3310	COG2188	Transcriptional regulator
AS86_3311	COG0531	amino acid
AS86_3315	COG0714	Associated with various cellular activities
AS86_3316	COG4548	von Willebrand factor, type A
AS86_3318	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS86_3319	COG0156	8-amino-7-oxononanoate synthase activity
AS86_3322	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_3323	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_3324	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS86_3325	COG3104	oligopeptide transport
AS86_3328	COG1620	l-lactate permease
AS86_3329	COG1027	Aspartate ammonia-lyase
AS86_3330	COG1253	flavin adenine dinucleotide binding
AS86_3331	COG0346	lactoylglutathione lyase activity
AS86_3332	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_3333	COG1316	TRANSCRIPTIONal
AS86_3334	COG2720	vancomycin resistance protein
AS86_3338	COG3227	Zinc metalloprotease (Elastase)
AS86_3341	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS86_3342	COG2217	Heavy metal translocating P-type atpase
AS86_3343	COG0640	Transcriptional regulator
AS86_3344	COG0531	amino acid
AS86_3347	COG2427	Protein of unknown function (DUF1641)
AS86_3348	COG3383	formate dehydrogenase (NAD+) activity
AS86_3349	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS86_3355	COG5002	protein histidine kinase activity
AS86_336	COG5377	YqaJ viral recombinase family
AS86_3361	COG0281	malic enzyme
AS86_3362	COG3493	citrate carrier protein
AS86_3363	COG4565	transcriptional regulatory protein
AS86_3364	COG3290	protein histidine kinase activity
AS86_3366	COG4990	cell redox homeostasis
AS86_3368	COG5002	protein histidine kinase activity
AS86_3369	COG0745	RESPONSE REGULATOR receiver
AS86_337	COG3723	Recombinational DNA repair protein, rece pathway
AS86_3370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS86_3372	COG0395	ABC-type sugar transport system, permease component
AS86_3373	COG1175	transmembrane transport
AS86_3374	COG3842	ATPase activity
AS86_3375	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS86_3380	COG2851	Citrate transporter
AS86_3381	COG4565	transcriptional regulatory protein
AS86_3382	COG3290	protein histidine kinase activity
AS86_3384	COG2268	Band 7 protein
AS86_3385	COG1585	Membrane protein implicated in regulation of membrane protease activity
AS86_3387	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS86_3390	COG2766	serine protein kinase
AS86_3393	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AS86_3398	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AS86_34	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AS86_341	COG1484	DNA-dependent DNA replication
AS86_3425	COG0735	belongs to the Fur family
AS86_3426	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS86_3430	COG4555	ABC transporter
AS86_3432	COG0069	glutamate synthase activity
AS86_3432	COG0070	glutamate synthase
AS86_3432	COG0067	glutamate synthase
AS86_3433	COG4129	membrane
AS86_3434	COG1132	(ABC) transporter
AS86_3439	COG1194	a g-specific adenine glycosylase
AS86_3440	COG1988	membrane-bound metal-dependent
AS86_3446	COG1090	epimerase
AS86_3447	COG1228	amidohydrolase
AS86_3451	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AS86_3453	COG0463	Glycosyl transferase, family 2
AS86_3454	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AS86_3454	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS86_3456	COG0463	Glycosyl transferase, family 2
AS86_3459	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS86_3460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS86_3460	COG1263	PTS System
AS86_3461	COG2066	Belongs to the glutaminase family
AS86_3466	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS86_3467	COG0833	amino acid
AS86_3469	COG3829	transcription factor binding
AS86_3473	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AS86_3474	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AS86_3478	COG0535	radical SAM domain protein
AS86_3480	COG0387	Pfam Sodium calcium exchanger
AS86_3481	COG3871	stress protein (general stress protein 26)
AS86_3484	COG0586	Pfam SNARE associated Golgi protein
AS86_3488	COG0697	spore germination
AS86_3489	COG2217	Heavy metal translocating P-type atpase
AS86_3490	COG1295	ribonuclease BN
AS86_3492	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AS86_3495	COG3853	Toxic anion resistance protein (TelA)
AS86_3497	COG0861	Integral membrane protein TerC family
AS86_3498	COG2310	stress, protein
AS86_3499	COG2310	stress, protein
AS86_35	COG1358	cellular component organization or biogenesis
AS86_350	COG3617	BRO family, N-terminal domain
AS86_3500	COG2310	stress, protein
AS86_3506	COG2270	Major facilitator Superfamily
AS86_3515	COG0488	(ABC) transporter
AS86_3516	COG1116	anion transmembrane transporter activity
AS86_3517	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS86_3518	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS86_3522	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AS86_3528	COG2190	(PTS) system
AS86_3528	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS86_3528	COG1263	PTS System
AS86_3529	COG0366	Alpha amylase catalytic
AS86_3530	COG0277	FAD linked oxidase domain protein
AS86_3532	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS86_3533	COG0549	Belongs to the carbamate kinase family
AS86_3538	COG0840	transmembrane signaling receptor activity
AS86_3539	COG1126	abc transporter atp-binding protein
AS86_3540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS86_3541	COG0765	amino acid transport
AS86_3543	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AS86_3543	COG0723	plastoquinol--plastocyanin reductase activity
AS86_3544	COG2814	Major facilitator Superfamily
AS86_3545	COG3541	Predicted nucleotidyltransferase
AS86_3549	COG5002	protein histidine kinase activity
AS86_355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS86_3554	COG0166	Belongs to the GPI family
AS86_3557	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS86_3558	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_3559	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_3561	COG2801	Transposase and inactivated derivatives
AS86_3562	COG0235	Class ii aldolase
AS86_3564	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AS86_3565	COG0450	alkyl hydroperoxide reductase
AS86_3568	COG1473	amidohydrolase
AS86_3575	COG4807	Protein conserved in bacteria
AS86_3576	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS86_3578	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_3582	COG2309	aminopeptidase activity
AS86_3584	COG2076	Multidrug Resistance protein
AS86_3585	COG1012	belongs to the aldehyde dehydrogenase family
AS86_3587	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AS86_3589	COG1597	lipid kinase activity
AS86_3593	COG4682	membrane
AS86_3594	COG1846	Transcriptional regulator
AS86_3595	COG0003	Pfam Anion-transporting ATPase
AS86_3598	COG1464	Belongs to the NlpA lipoprotein family
AS86_3599	COG2011	ABC-type metal ion transport system permease component
AS86_3601	COG1335	isochorismatase
AS86_3604	COG4851	CamS sex pheromone cAM373 precursor
AS86_3606	COG0210	DNA helicase
AS86_3611	COG0151	Belongs to the GarS family
AS86_3613	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AS86_3615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AS86_3618	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS86_3620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AS86_3621	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AS86_3622	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS86_3628	COG0697	spore germination
AS86_3633	COG0745	RESPONSE REGULATOR receiver
AS86_3634	COG2205	protein histidine kinase activity
AS86_3644	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AS86_3650	COG5002	protein histidine kinase activity
AS86_3652	COG2252	PERMEase
AS86_3654	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AS86_3657	COG2946	Replication initiation factor
AS86_3659	COG1674	ftsk spoiiie
AS86_3684	COG0582	viral genome integration into host DNA
AS86_3687	COG1266	CAAX protease self-immunity
AS86_3690	COG0488	(ABC) transporter
AS86_3692	COG0456	acetyltransferase
AS86_3693	COG1214	PFAM Peptidase M22, glycoprotease
AS86_3694	COG0802	atpase or kinase
AS86_37	COG1550	Protein conserved in bacteria
AS86_3714	COG2183	response to ionizing radiation
AS86_3715	COG2337	Toxic component of a toxin-antitoxin (TA) module
AS86_3716	COG0864	Transcriptional regulator
AS86_3717	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AS86_3718	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AS86_3720	COG4294	response to UV
AS86_3721	COG0705	Rhomboid family
AS86_3723	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS86_3725	COG2814	Major facilitator Superfamily
AS86_3726	COG0531	amino acid
AS86_3728	COG0179	Fumarylacetoacetate (FAA) hydrolase
AS86_3729	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AS86_3734	COG0561	phosphatase activity
AS86_3735	COG4608	Belongs to the ABC transporter superfamily
AS86_3736	COG0444	Belongs to the ABC transporter superfamily
AS86_3738	COG0601	transmembrane transport
AS86_3739	COG0747	negative chemotaxis
AS86_3741	COG0488	(ABC) transporter
AS86_3745	COG5298	Protein conserved in bacteria
AS86_3749	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_375	COG1388	LysM domain
AS86_375	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_375	COG3409	Peptidoglycan-binding domain 1 protein
AS86_3751	COG1609	Transcriptional regulator
AS86_3753	COG0204	Acyl-transferase
AS86_3756	COG0697	spore germination
AS86_3759	COG1910	domain protein
AS86_3760	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS86_3761	COG4149	molybdate abc transporter
AS86_3765	COG0656	L-ascorbic acid biosynthetic process
AS86_3766	COG4166	transmembrane transport
AS86_3767	COG4166	transmembrane transport
AS86_3770	COG4166	transmembrane transport
AS86_3771	COG4608	Belongs to the ABC transporter superfamily
AS86_3772	COG0444	Belongs to the ABC transporter superfamily
AS86_3773	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS86_3774	COG0601	transmembrane transport
AS86_3778	COG2814	Major facilitator Superfamily
AS86_3780	COG2271	Major facilitator Superfamily
AS86_3781	COG0277	FAD linked oxidase domain protein
AS86_3783	COG0604	alcohol dehydrogenase
AS86_3784	COG1464	Belongs to the NlpA lipoprotein family
AS86_3785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AS86_3786	COG2011	ABC-type metal ion transport system permease component
AS86_3787	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_3793	COG4856	YbbR-like protein
AS86_3794	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS86_3811	COG0726	polysaccharide deacetylase
AS86_3812	COG2194	sulfuric ester hydrolase activity
AS86_3814	COG0489	protein tyrosine kinase activity
AS86_3815	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS86_3820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS86_3827	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AS86_3829	COG0024	Methionine aminopeptidase
AS86_383	COG3383	formate dehydrogenase (NAD+) activity
AS86_3831	COG0201	protein transport
AS86_3836	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AS86_384	COG2427	Protein of unknown function (DUF1641)
AS86_385	COG5609	conserved protein (DUF2294)
AS86_3857	COG1358	cellular component organization or biogenesis
AS86_386	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AS86_3860	COG2813	Specifically methylates the guanine in position
AS86_3865	COG0250	Participates in transcription elongation, termination and antitermination
AS86_3866	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS86_3868	COG3688	RNA-binding protein containing a PIN domain
AS86_3869	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS86_3872	COG1045	serine acetyltransferase
AS86_3876	COG4956	integral membrane protein (PIN domain superfamily)
AS86_3878	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS86_3879	COG0542	response to heat
AS86_388	COG2116	formate transmembrane transporter activity
AS86_3881	COG3880	PFAM UvrB UvrC protein
AS86_389	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS86_390	COG0303	'Molybdopterin
AS86_3903	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AS86_3904	COG1396	sequence-specific DNA binding
AS86_3905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS86_3906	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AS86_3907	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AS86_3908	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AS86_3909	COG0512	Glutamine amidotransferase of anthranilate synthase
AS86_391	COG0314	molybdopterin synthase activity
AS86_3910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS86_3911	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS86_3914	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS86_3917	COG2208	phosphoserine phosphatase activity
AS86_3920	COG1098	S1 RNA binding domain
AS86_3924	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS86_3925	COG3956	TIGRFAM MazG family protein
AS86_3926	COG2244	polysaccharide biosynthetic process
AS86_3927	COG2002	toxin-antitoxin pair type II binding
AS86_3928	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AS86_393	COG0489	protein tyrosine kinase activity
AS86_3931	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS86_3934	COG0251	oxidation-reduction process
AS86_3935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS86_3938	COG4466	Protein conserved in bacteria
AS86_3942	COG0084	hydrolase, TatD family'
AS86_3944	COG2002	toxin-antitoxin pair type II binding
AS86_3945	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AS86_3947	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AS86_3949	COG1774	PSP1 C-terminal conserved region
AS86_3950	COG0470	DNA polymerase III
AS86_3952	COG1982	Orn Lys Arg decarboxylase major
AS86_396	COG3326	Membrane
AS86_3964	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS86_3965	COG0590	tRNA wobble adenosine to inosine editing
AS86_3966	COG1335	isochorismatase
AS86_3967	COG1428	Deoxynucleoside kinase
AS86_3968	COG1428	Deoxynucleoside kinase
AS86_397	COG2962	Rard protein
AS86_3974	COG1686	Belongs to the peptidase S11 family
AS86_3975	COG0516	GMP reductase activity
AS86_3975	COG0517	IMP dehydrogenase activity
AS86_398	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AS86_3983	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS86_3984	COG0187	DNA topoisomerase II activity
AS86_3986	COG2501	S4 domain
AS86_3987	COG0592	DNA-directed DNA polymerase activity
AS86_399	COG1657	PFAM Prenyltransferase squalene oxidase
AS86_3992	COG1847	R3H domain protein
AS86_3997	COG1192	Involved in chromosome partitioning
AS86_3998	COG1475	DNA binding
AS86_4	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS86_40	COG0196	riboflavin kinase activity
AS86_4000	COG0668	transmembrane transport
AS86_4001	COG4481	Protein conserved in bacteria
AS86_4002	COG0012	GTP binding
AS86_4004	COG0629	single-stranded DNA binding
AS86_4006	COG4241	membrane
AS86_4007	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AS86_4009	COG0305	Participates in initiation and elongation during chromosome replication
AS86_401	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_4015	COG0745	RESPONSE REGULATOR receiver
AS86_4016	COG5002	protein histidine kinase activity
AS86_4018	COG4853	Protein conserved in bacteria
AS86_4019	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS86_402	COG1012	belongs to the aldehyde dehydrogenase family
AS86_4020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS86_4023	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS86_4034	COG0322	excinuclease ABC activity
AS86_4036	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS86_404	COG4145	pantothenate transmembrane transporter activity
AS86_4046	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS86_4048	COG2801	Transposase and inactivated derivatives
AS86_4051	COG1164	Oligoendopeptidase f
AS86_4055	COG1272	protein, Hemolysin III
AS86_4056	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS86_4062	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AS86_4063	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS86_4064	COG2814	Major facilitator Superfamily
AS86_4065	COG3275	phosphorelay sensor kinase activity
AS86_4069	COG0628	permease
AS86_407	COG0165	Argininosuccinate lyase
AS86_4070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS86_4070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AS86_4071	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS86_4072	COG1309	transcriptional regulator
AS86_4073	COG0488	(ABC) transporter
AS86_4074	COG1309	transcriptional regulator
AS86_4076	COG0463	Glycosyl transferase, family 2
AS86_4077	COG4485	Bacterial membrane protein, YfhO
AS86_4079	COG1216	Glycosyl transferase, family 2
AS86_4082	COG1216	Glycosyl transferase, family 2
AS86_4083	COG1607	acyl-coa hydrolase
AS86_4085	COG0840	transmembrane signaling receptor activity
AS86_4088	COG0438	transferase activity, transferring glycosyl groups
AS86_409	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_4090	COG0477	Major facilitator Superfamily
AS86_4091	COG3279	Response regulator of the LytR AlgR family
AS86_4092	COG1966	Carbon starvation protein
AS86_4093	COG2879	small protein
AS86_4094	COG3706	GGDEF domain
AS86_4095	COG0351	phosphomethylpyrimidine kinase
AS86_4096	COG2203	Gaf domain
AS86_4096	COG4585	Histidine kinase
AS86_4097	COG2197	response regulator
AS86_4099	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS86_4100	COG1011	Hydrolase
AS86_4104	COG0460	homoserine dehydrogenase
AS86_4106	COG1609	Transcriptional regulator
AS86_4107	COG2755	lipolytic protein G-D-S-L family
AS86_4108	COG1131	(ABC) transporter
AS86_4109	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AS86_4111	COG2814	Major facilitator Superfamily
AS86_4112	COG0561	phosphatase activity
AS86_4113	COG2233	PERMEase
AS86_4114	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS86_4116	COG2363	Small membrane protein
AS86_4118	COG3773	Cell wall hydrolase
AS86_4121	COG0280	phosphate acetyltransferase
AS86_4125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_4126	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS86_4127	COG1120	ATPase activity
AS86_4128	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS86_4129	COG1078	dGTPase activity
AS86_413	COG1051	belongs to the nudix hydrolase family
AS86_4131	COG1994	Peptidase M50
AS86_4133	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS86_4134	COG0584	glycerophosphoryl diester phosphodiesterase
AS86_4135	COG0789	Transcriptional regulator
AS86_4136	COG2814	Major facilitator Superfamily
AS86_4137	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS86_4141	COG1619	proteins homologs of microcin C7 resistance protein MccF
AS86_4142	COG4506	Protein conserved in bacteria
AS86_4144	COG1595	DNA-templated transcription, initiation
AS86_4148	COG2234	aminopeptidase activity
AS86_415	COG0716	FMN binding
AS86_4150	COG0024	Methionine aminopeptidase
AS86_4151	COG1131	(ABC) transporter
AS86_4152	COG0842	Transport permease protein
AS86_4153	COG4585	Histidine kinase
AS86_4154	COG2197	response regulator
AS86_4155	COG3227	Zinc metalloprotease (Elastase)
AS86_4158	COG3300	MHYT domain
AS86_4158	COG5001	Diguanylate cyclase
AS86_4160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AS86_4169	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AS86_417	COG1278	Cold shock
AS86_4170	COG1404	Belongs to the peptidase S8 family
AS86_4177	COG3620	sequence-specific DNA binding
AS86_4178	COG0247	lactate metabolic process
AS86_4178	COG2181	nitrate reductase activity
AS86_4179	COG0183	Belongs to the thiolase family
AS86_4180	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS86_4181	COG1960	acyl-CoA dehydrogenase activity
AS86_4182	COG1960	acyl-CoA dehydrogenase activity
AS86_4186	COG4821	SIS domain
AS86_4190	COG1494	fructose-1,6-bisphosphatase
AS86_4191	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS86_4194	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AS86_4198	COG0009	L-threonylcarbamoyladenylate synthase
AS86_4203	COG2801	Transposase and inactivated derivatives
AS86_4204	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS86_4205	COG2259	Doxx family
AS86_4206	COG2190	(PTS) system
AS86_4208	COG0698	ribose 5-phosphate isomerase
AS86_4214	COG0356	it plays a direct role in the translocation of protons across the membrane
AS86_4224	COG3300	MHYT domain
AS86_4224	COG5001	Diguanylate cyclase
AS86_4227	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS86_423	COG2720	vancomycin resistance protein
AS86_4231	COG0839	Belongs to the complex I subunit 6 family
AS86_4233	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS86_4234	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AS86_4235	COG1007	ATP synthesis coupled electron transport
AS86_4236	COG4836	Membrane
AS86_4238	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AS86_4239	COG2385	sporulation resulting in formation of a cellular spore
AS86_4240	COG3279	Response regulator of the LytR AlgR family
AS86_4243	COG0739	heme binding
AS86_4244	COG1609	Transcriptional regulator
AS86_4247	COG0489	protein tyrosine kinase activity
AS86_4248	COG3944	biosynthesis protein
AS86_4249	COG0489	protein tyrosine kinase activity
AS86_425	COG2514	catechol 2,3-dioxygenase activity
AS86_4250	COG4464	protein tyrosine phosphatase activity
AS86_4251	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS86_4255	COG0438	transferase activity, transferring glycosyl groups
AS86_4256	COG1215	transferase activity, transferring glycosyl groups
AS86_4257	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS86_4258	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AS86_4261	COG0745	RESPONSE REGULATOR receiver
AS86_4262	COG5002	protein histidine kinase activity
AS86_4269	COG1136	(ABC) transporter
AS86_427	COG1285	pathogenesis
AS86_4270	COG0577	efflux transmembrane transporter activity
AS86_4272	COG1191	sigma factor activity
AS86_4278	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS86_4279	COG4715	Zinc finger, swim domain protein
AS86_4284	COG1388	LysM domain
AS86_4284	COG3584	3D domain protein
AS86_4285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS86_4287	COG1215	transferase activity, transferring glycosyl groups
AS86_4289	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_429	COG3852	Histidine kinase
AS86_4291	COG1388	LysM domain
AS86_4291	COG0791	NLP P60 protein
AS86_4293	COG1368	sulfuric ester hydrolase activity
AS86_4295	COG2389	metal-binding protein
AS86_4297	COG1620	l-lactate permease
AS86_4299	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS86_43	COG0726	polysaccharide deacetylase
AS86_4300	COG1294	oxidase, subunit
AS86_4301	COG1271	oxidase subunit
AS86_4304	COG0583	DNA-binding transcription factor activity
AS86_4305	COG1511	domain protein
AS86_4308	COG1301	dicarboxylic acid transport
AS86_4309	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS86_4311	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS86_4313	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AS86_4315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AS86_4316	COG1447	Phosphotransferase system cellobiose-specific component IIA
AS86_4317	COG1486	melibiose metabolic process
AS86_4321	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AS86_4321	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AS86_4323	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS86_4324	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AS86_4325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS86_4326	COG1316	TRANSCRIPTIONal
AS86_4327	COG1739	Uncharacterized protein family UPF0029
AS86_4328	COG1307	EDD domain protein, DegV family
AS86_4329	COG1733	regulation of RNA biosynthetic process
AS86_4330	COG0791	NLP P60 protein
AS86_4330	COG1388	LysM domain
AS86_4331	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AS86_4332	COG1040	competence protein
AS86_4333	COG1278	Cold shock
AS86_4334	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AS86_4336	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AS86_4338	COG2884	Cell division ATP-binding protein ftsE
AS86_4339	COG2177	Part of the ABC transporter FtsEX involved in
AS86_434	COG1876	peptidase activity
AS86_4340	COG3409	Peptidoglycan-binding domain 1 protein
AS86_4340	COG0793	Belongs to the peptidase S41A family
AS86_4341	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS86_4342	COG1132	(ABC) transporter
AS86_4344	COG0488	(ABC) transporter
AS86_4345	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS86_4347	COG0583	DNA-binding transcription factor activity
AS86_4351	COG0789	Transcriptional regulator
AS86_4355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AS86_4357	COG1950	PFAM Membrane protein of
AS86_4361	COG0110	maltose O-acetyltransferase activity
AS86_4362	COG0457	Tetratricopeptide repeat
AS86_4363	COG0492	ferredoxin-NADP+ reductase activity
AS86_4365	COG1051	belongs to the nudix hydrolase family
AS86_4367	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS86_4369	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS86_4371	COG2323	membrane
AS86_4374	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS86_4379	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AS86_4382	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS86_4389	COG1346	cytolysis
AS86_4390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS86_4391	COG1647	Serine aminopeptidase, S33
AS86_4392	COG0557	exoribonuclease II activity
AS86_44	COG0612	Peptidase, M16
AS86_4400	COG2233	PERMEase
AS86_4401	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AS86_4402	COG0288	reversible hydration of carbon dioxide
AS86_4403	COG1522	sequence-specific DNA binding
AS86_4405	COG1522	sequence-specific DNA binding
AS86_4406	COG1335	isochorismatase
AS86_4408	COG3223	Belongs to the PsiE family
AS86_4410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_4411	COG0488	(ABC) transporter
AS86_4418	COG3290	protein histidine kinase activity
AS86_4418	COG0840	transmembrane signaling receptor activity
AS86_4422	COG1252	NADH dehydrogenase
AS86_4424	COG1733	regulation of RNA biosynthetic process
AS86_4425	COG2814	Major facilitator Superfamily
AS86_4426	COG0656	L-ascorbic acid biosynthetic process
AS86_4429	COG2910	NAD(P)H-binding
AS86_443	COG1396	sequence-specific DNA binding
AS86_4430	COG1115	amino acid carrier protein
AS86_4431	COG1115	amino acid carrier protein
AS86_4432	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_4433	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_4435	COG1528	Iron-storage protein
AS86_4437	COG1611	Belongs to the LOG family
AS86_4440	COG0783	Belongs to the Dps family
AS86_4441	COG1115	amino acid carrier protein
AS86_4442	COG0490	domain, Protein
AS86_4443	COG0475	glutathione-regulated potassium exporter activity
AS86_4444	COG0586	Pfam SNARE associated Golgi protein
AS86_4448	COG3227	Zinc metalloprotease (Elastase)
AS86_4449	COG2801	Transposase and inactivated derivatives
AS86_4451	COG2151	metal-sulfur cluster biosynthetic enzyme
AS86_4452	COG0840	transmembrane signaling receptor activity
AS86_4458	COG5002	protein histidine kinase activity
AS86_4459	COG0745	RESPONSE REGULATOR receiver
AS86_4460	COG1376	ErfK ybiS ycfS ynhG family protein
AS86_4462	COG0586	Pfam SNARE associated Golgi protein
AS86_4469	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_4474	COG0531	amino acid
AS86_4475	COG2814	Major facilitator Superfamily
AS86_4478	COG0840	transmembrane signaling receptor activity
AS86_4479	COG0011	TIGRFAM Protein of
AS86_4482	COG1686	Belongs to the peptidase S11 family
AS86_4484	COG1250	3-hydroxyacyl-CoA dehydrogenase
AS86_4484	COG1024	Enoyl-CoA hydratase
AS86_4485	COG0183	Belongs to the thiolase family
AS86_4486	COG1960	acyl-CoA dehydrogenase activity
AS86_4487	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_4490	COG0039	L-malate dehydrogenase activity
AS86_4494	COG1393	Belongs to the ArsC family
AS86_4496	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS86_4497	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS86_45	COG1873	PFAM PRC-barrel domain
AS86_4500	COG2011	ABC-type metal ion transport system permease component
AS86_4501	COG1464	Belongs to the NlpA lipoprotein family
AS86_4502	COG1464	Belongs to the NlpA lipoprotein family
AS86_4503	COG0396	ATPase activity
AS86_4504	COG0719	Fe-S assembly protein
AS86_4505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AS86_4506	COG0822	iron-sulfur transferase activity
AS86_4507	COG0719	Fe-S assembly protein
AS86_4508	COG0737	Belongs to the 5'-nucleotidase family
AS86_4509	COG3377	Domain of unknown function (DUF1805)
AS86_4511	COG0739	heme binding
AS86_4516	COG4377	Putative membrane peptidase family (DUF2324)
AS86_4517	COG0789	Transcriptional regulator
AS86_4519	COG4470	Protein conserved in bacteria
AS86_4522	COG1494	fructose-1,6-bisphosphatase
AS86_4523	COG2445	Protein of unknown function DUF86
AS86_4525	COG0647	UMP catabolic process
AS86_4526	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS86_4528	COG1358	cellular component organization or biogenesis
AS86_4532	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AS86_4533	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AS86_4535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS86_4536	COG4837	Protein of unknown function (DUF1462)
AS86_4544	COG2824	Alkylphosphonate utilization operon protein PhnA
AS86_4545	COG0390	transport system, permease component
AS86_4546	COG2274	protein secretion by the type I secretion system
AS86_4547	COG1252	NADH dehydrogenase
AS86_4550	COG0316	Belongs to the HesB IscA family
AS86_4556	COG1683	Conserved Protein
AS86_4559	COG3708	Transcriptional regulator
AS86_4561	COG1252	NADH dehydrogenase
AS86_4564	COG3584	3D domain protein
AS86_4567	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AS86_4568	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AS86_4569	COG1268	BioY protein
AS86_4571	COG2050	protein possibly involved in aromatic compounds catabolism
AS86_4572	COG0423	glycine-tRNA ligase activity
AS86_4575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS86_4576	COG5018	Exonuclease
AS86_4580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AS86_4582	COG2267	carboxylic ester hydrolase activity
AS86_4583	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS86_4584	COG1522	sequence-specific DNA binding
AS86_4585	COG0436	Aminotransferase
AS86_4586	COG1098	S1 RNA binding domain
AS86_4587	COG2155	Conserved Protein
AS86_4589	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AS86_4591	COG1285	pathogenesis
AS86_46	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AS86_4621	COG1309	transcriptional regulator
AS86_4622	COG0039	L-malate dehydrogenase activity
AS86_4626	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AS86_4628	COG0058	SHG alpha-glucan phosphorylase activity
AS86_4634	COG1278	Cold shock
AS86_4635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS86_4636	COG1575	Belongs to the MenA family. Type 1 subfamily
AS86_4637	COG1169	isochorismate synthase
AS86_4639	COG0596	Alpha beta hydrolase
AS86_4640	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AS86_4642	COG4948	Mandelate Racemase Muconate Lactonizing
AS86_4646	COG3964	amidohydrolase
AS86_4653	COG0577	efflux transmembrane transporter activity
AS86_4654	COG1136	(ABC) transporter
AS86_4655	COG0577	efflux transmembrane transporter activity
AS86_4656	COG0577	efflux transmembrane transporter activity
AS86_4657	COG2205	protein histidine kinase activity
AS86_4658	COG0745	RESPONSE REGULATOR receiver
AS86_4660	COG0640	Transcriptional regulator
AS86_4661	COG5658	integral membrane protein
AS86_4662	COG1131	(ABC) transporter
AS86_4664	COG3708	Transcriptional regulator
AS86_4664	COG2207	Transcriptional regulator
AS86_4665	COG1136	(ABC) transporter
AS86_4666	COG0577	efflux transmembrane transporter activity
AS86_4668	COG0586	Pfam SNARE associated Golgi protein
AS86_467	COG0582	viral genome integration into host DNA
AS86_4670	COG5002	protein histidine kinase activity
AS86_4681	COG1597	lipid kinase activity
AS86_4687	COG0745	RESPONSE REGULATOR receiver
AS86_4688	COG5002	protein histidine kinase activity
AS86_4689	COG3859	Proton-coupled thiamine transporter YuaJ
AS86_4694	COG1842	Phage shock protein A
AS86_4699	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_47	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS86_4703	COG1294	oxidase, subunit
AS86_4704	COG1271	oxidase subunit
AS86_4706	COG0288	reversible hydration of carbon dioxide
AS86_4708	COG0789	Transcriptional regulator
AS86_4709	COG2076	Multidrug Resistance protein
AS86_4710	COG2076	Multidrug Resistance protein
AS86_4716	COG0494	nUDIX hydrolase
AS86_4721	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS86_4722	COG1116	anion transmembrane transporter activity
AS86_4723	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AS86_4726	COG4895	conserved protein (DUF2196)
AS86_4728	COG1368	sulfuric ester hydrolase activity
AS86_4729	COG2267	carboxylic ester hydrolase activity
AS86_4731	COG3852	Histidine kinase
AS86_4732	COG5002	protein histidine kinase activity
AS86_4750	COG0438	transferase activity, transferring glycosyl groups
AS86_4751	COG0671	phosphoesterase, PA-phosphatase related
AS86_4752	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AS86_4753	COG2267	carboxylic ester hydrolase activity
AS86_4756	COG1794	racemase activity, acting on amino acids and derivatives
AS86_4757	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AS86_4758	COG1242	4 iron, 4 sulfur cluster binding
AS86_476	COG4626	Terminase
AS86_476	COG1802	Transcriptional regulator
AS86_4762	COG1136	(ABC) transporter
AS86_4764	COG0582	viral genome integration into host DNA
AS86_4765	COG0490	domain, Protein
AS86_4766	COG0475	glutathione-regulated potassium exporter activity
AS86_4767	COG2814	Major facilitator Superfamily
AS86_4775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS86_4777	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS86_478	COG0740	serine-type endopeptidase activity
AS86_4781	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AS86_4782	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS86_4784	COG0303	'Molybdopterin
AS86_4785	COG1763	Mo-molybdopterin cofactor biosynthetic process
AS86_4786	COG0314	molybdopterin synthase activity
AS86_4791	COG1329	Transcriptional regulator
AS86_4795	COG3832	glyoxalase III activity
AS86_4797	COG2814	Major facilitator Superfamily
AS86_4798	COG2081	HI0933 family
AS86_4799	COG2244	polysaccharide biosynthetic process
AS86_4800	COG1187	pseudouridine synthase activity
AS86_4801	COG1349	DNA-binding transcription factor activity
AS86_4802	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AS86_4804	COG1523	belongs to the glycosyl hydrolase 13 family
AS86_4805	COG0510	thiamine kinase activity
AS86_4808	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_4810	COG1363	Peptidase, m42
AS86_4811	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AS86_4812	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS86_4814	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS86_4817	COG1674	ftsk spoiiie
AS86_4820	COG0789	Transcriptional regulator
AS86_4821	COG0697	spore germination
AS86_4822	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_4825	COG2309	aminopeptidase activity
AS86_4827	COG3118	belongs to the thioredoxin family
AS86_4828	COG4851	CamS sex pheromone cAM373 precursor
AS86_4829	COG1609	Transcriptional regulator
AS86_4835	COG0666	response to abiotic stimulus
AS86_4836	COG5002	protein histidine kinase activity
AS86_4837	COG0745	RESPONSE REGULATOR receiver
AS86_4840	COG0123	including yeast histone deacetylase and acetoin utilization protein
AS86_4841	COG0517	IMP dehydrogenase activity
AS86_4842	COG0454	-acetyltransferase
AS86_4843	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS86_4844	COG0110	maltose O-acetyltransferase activity
AS86_4849	COG0626	cystathionine gamma-synthase activity
AS86_4850	COG1956	GAF domain-containing protein
AS86_4851	COG1309	transcriptional regulator
AS86_4852	COG0697	spore germination
AS86_4853	COG0583	DNA-binding transcription factor activity
AS86_4855	COG1104	cysteine desulfurase activity
AS86_4858	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS86_4860	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AS86_4863	COG3874	Sporulation protein YtfJ
AS86_4864	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AS86_4865	COG0827	DNA restriction-modification system
AS86_4870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_4879	COG0589	response to stress
AS86_4880	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_4883	COG0662	Cupin 2, conserved barrel domain protein
AS86_4884	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_4890	COG0006	proline dipeptidase activity
AS86_4893	COG4109	DRTGG domain
AS86_4896	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS86_4899	COG0587	DNA-directed DNA polymerase activity
AS86_490	COG4824	toxin secretion phage lysis holin
AS86_4900	COG0281	malic enzyme
AS86_4901	COG1725	Transcriptional regulator
AS86_4906	COG3030	protein affecting phage T7 exclusion by the F plasmid
AS86_4907	COG0628	permease
AS86_4909	COG0372	Belongs to the citrate synthase family
AS86_4910	COG0538	isocitrate dehydrogenase activity
AS86_4915	COG0745	RESPONSE REGULATOR receiver
AS86_4916	COG5002	protein histidine kinase activity
AS86_4917	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS86_4917	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS86_4919	COG1971	Probably functions as a manganese efflux pump
AS86_4920	COG0237	dephospho-CoA kinase activity
AS86_4921	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AS86_4922	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AS86_4924	COG3611	Membrane attachment protein
AS86_4925	COG1484	DNA-dependent DNA replication
AS86_4928	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AS86_4933	COG1363	Peptidase, m42
AS86_4934	COG1309	transcriptional regulator
AS86_4935	COG1566	PFAM secretion protein HlyD family protein
AS86_4936	COG2814	Major facilitator Superfamily
AS86_4939	COG1418	mRNA catabolic process
AS86_4941	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS86_4944	COG0017	Asparaginyl-tRNA synthetase
AS86_4948	COG1286	toxin biosynthetic process
AS86_4949	COG1796	DNA polymerase
AS86_4949	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS86_4952	COG1187	pseudouridine synthase activity
AS86_4953	COG1114	Component of the transport system for branched-chain amino acids
AS86_4954	COG5386	Cell surface protein
AS86_4956	COG5386	Cell surface protein
AS86_4959	COG1120	ATPase activity
AS86_4960	COG4509	Sortase family
AS86_4962	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS86_4963	COG4895	conserved protein (DUF2196)
AS86_4965	COG0745	RESPONSE REGULATOR receiver
AS86_4966	COG2205	protein histidine kinase activity
AS86_4967	COG1131	(ABC) transporter
AS86_4971	COG2318	DinB family
AS86_4976	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_4977	COG1309	transcriptional regulator
AS86_4978	COG1024	Enoyl-CoA hydratase
AS86_4979	COG2086	electron transfer activity
AS86_4980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AS86_4981	COG3118	belongs to the thioredoxin family
AS86_4983	COG1719	4-vinyl reductase, 4VR
AS86_4984	COG2009	succinate dehydrogenase
AS86_4985	COG1053	succinate dehydrogenase
AS86_4986	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS86_4987	COG0824	Thioesterase
AS86_4988	COG1876	peptidase activity
AS86_4989	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AS86_4990	COG1360	Flagellar Motor Protein
AS86_4991	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AS86_4992	COG4152	abc transporter atp-binding protein
AS86_4993	COG1668	transmembrane transport
AS86_4994	COG1959	2 iron, 2 sulfur cluster binding
AS86_4996	COG0697	spore germination
AS86_4997	COG1396	sequence-specific DNA binding
AS86_4998	COG1983	PspC domain protein
AS86_4999	COG0402	S-adenosylhomocysteine deaminase activity
AS86_5000	COG2233	PERMEase
AS86_5001	COG2197	response regulator
AS86_5003	COG1309	transcriptional regulator
AS86_5007	COG5401	PFAM Sporulation and spore germination
AS86_5010	COG0622	Phosphoesterase
AS86_5014	COG2801	Transposase and inactivated derivatives
AS86_5022	COG0470	DNA polymerase III
AS86_5022	COG1067	ATP-dependent peptidase activity
AS86_5025	COG1764	response to oxidative stress
AS86_5026	COG1846	Transcriptional regulator
AS86_5028	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS86_503	COG1309	transcriptional regulator
AS86_5030	COG1587	Uroporphyrinogen-III synthase
AS86_5031	COG0113	porphobilinogen synthase activity
AS86_5033	COG1388	LysM domain
AS86_5036	COG0285	dihydrofolate synthase activity
AS86_5040	COG1077	Cell shape determining protein MreB Mrl
AS86_5041	COG1792	Involved in formation and maintenance of cell shape
AS86_5044	COG2894	cell division
AS86_5045	COG0739	heme binding
AS86_5046	COG1994	Peptidase M50
AS86_5047	COG1530	ribonuclease E activity
AS86_5049	COG2868	ribosomal protein
AS86_5051	COG3290	protein histidine kinase activity
AS86_5053	COG0745	RESPONSE REGULATOR receiver
AS86_5054	COG5002	protein histidine kinase activity
AS86_5055	COG1136	(ABC) transporter
AS86_5056	COG0577	efflux transmembrane transporter activity
AS86_5057	COG0577	efflux transmembrane transporter activity
AS86_5058	COG0077	Prephenate dehydratase
AS86_5060	COG2258	MOSC domain
AS86_5061	COG1827	regulation of RNA biosynthetic process
AS86_5062	COG1104	cysteine desulfurase activity
AS86_5063	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AS86_5064	COG0157	Belongs to the NadC ModD family
AS86_5070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS86_5076	COG1862	Preprotein translocase
AS86_5078	COG2323	membrane
AS86_5079	COG2244	polysaccharide biosynthetic process
AS86_5081	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS86_5081	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS86_5082	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS86_5083	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS86_5083	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AS86_5085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AS86_5091	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AS86_5093	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS86_5094	COG1959	2 iron, 2 sulfur cluster binding
AS86_5095	COG1104	cysteine desulfurase activity
AS86_5098	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS86_51	COG1396	sequence-specific DNA binding
AS86_5102	COG0628	permease
AS86_5108	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AS86_5115	COG0768	penicillin binding
AS86_5120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS86_5121	COG0626	cystathionine gamma-synthase activity
AS86_5122	COG1012	belongs to the aldehyde dehydrogenase family
AS86_5122	COG1454	alcohol dehydrogenase
AS86_5124	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS86_5132	COG2259	Doxx family
AS86_5133	COG2514	catechol 2,3-dioxygenase activity
AS86_5135	COG3186	Phenylalanine-4-hydroxylase
AS86_5136	COG1404	Belongs to the peptidase S8 family
AS86_514	COG0457	Tetratricopeptide repeat
AS86_5143	COG2267	carboxylic ester hydrolase activity
AS86_5145	COG1785	Belongs to the alkaline phosphatase family
AS86_5147	COG2357	RelA SpoT domain protein
AS86_5148	COG0778	Nitroreductase
AS86_5150	COG1595	DNA-templated transcription, initiation
AS86_5152	COG1191	sigma factor activity
AS86_5155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AS86_5156	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS86_5158	COG1534	Rna-binding protein
AS86_5160	COG1713	HD superfamily hydrolase involved in NAD metabolism
AS86_5161	COG0799	negative regulation of ribosome biogenesis
AS86_5162	COG2226	methyltransferase
AS86_5163	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS86_5164	COG1596	polysaccharide export
AS86_5164	COG1555	photosystem II stabilization
AS86_5165	COG2131	deaminase
AS86_5166	COG0658	competence protein
AS86_5166	COG2333	competence protein COMEC
AS86_5168	COG1466	dna polymerase III delta subunit
AS86_5173	COG1733	regulation of RNA biosynthetic process
AS86_5174	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS86_518	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS86_5180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS86_5181	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS86_5183	COG1610	YqeY-like protein
AS86_5186	COG1702	phosphate starvation-inducible protein PhoH
AS86_5187	COG1480	7TM receptor with intracellular HD hydrolase
AS86_5189	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AS86_5190	COG0295	cytidine deaminase activity
AS86_5191	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AS86_5194	COG0517	IMP dehydrogenase activity
AS86_5196	COG0358	DNA primase activity
AS86_5197	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AS86_5199	COG2384	SAM-dependent methyltransferase
AS86_5200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AS86_5206	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_5207	COG1121	(ABC) transporter
AS86_5208	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS86_5209	COG0735	belongs to the Fur family
AS86_5212	COG5521	maltodextrose utilization protein MalA
AS86_5214	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AS86_5215	COG0477	Major facilitator Superfamily
AS86_5216	COG0582	viral genome integration into host DNA
AS86_522	COG0697	spore germination
AS86_5221	COG1396	sequence-specific DNA binding
AS86_5238	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS86_524	COG3397	chitin binding
AS86_525	COG0823	Involved in the tonB-independent uptake of proteins
AS86_5257	COG1388	LysM domain
AS86_5257	COG3409	Peptidoglycan-binding domain 1 protein
AS86_5257	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_5267	COG0573	inorganic phosphate transmembrane transporter activity
AS86_5268	COG0573	inorganic phosphate transmembrane transporter activity
AS86_527	COG0463	Glycosyl transferase, family 2
AS86_5270	COG0704	Plays a role in the regulation of phosphate uptake
AS86_5271	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AS86_5273	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS86_5274	COG4483	Protein conserved in bacteria
AS86_5275	COG1940	carbohydrate kinase activity
AS86_5277	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_528	COG0463	Glycosyl transferase, family 2
AS86_5281	COG0626	cystathionine gamma-synthase activity
AS86_5282	COG0626	cystathionine gamma-synthase activity
AS86_5283	COG0646	methionine synthase
AS86_5283	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS86_5284	COG0646	methionine synthase
AS86_5284	COG1410	methionine synthase
AS86_529	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS86_5295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS86_5296	COG1459	type II secretion system
AS86_5309	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS86_531	COG1088	dTDP-glucose 4,6-dehydratase activity
AS86_5317	COG2076	Multidrug Resistance protein
AS86_5318	COG2076	Multidrug Resistance protein
AS86_532	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AS86_5320	COG1609	Transcriptional regulator
AS86_5322	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS86_533	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AS86_5330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS86_5331	COG3872	metal-dependent enzyme
AS86_5334	COG0006	proline dipeptidase activity
AS86_5339	COG3854	ATPases associated with a variety of cellular activities
AS86_5347	COG0511	ligase activity, forming carbon-carbon bonds
AS86_5348	COG0439	Biotin carboxylase
AS86_5349	COG1302	Protein conserved in bacteria
AS86_5354	COG0142	geranyltranstransferase activity
AS86_5356	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AS86_5358	COG0497	DNA recombination
AS86_5359	COG0750	zinc metalloprotease
AS86_536	COG2089	acid synthase
AS86_5368	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AS86_537	COG0772	Belongs to the SEDS family
AS86_5371	COG2801	Transposase and inactivated derivatives
AS86_5377	COG3093	addiction module antidote protein HigA
AS86_5378	COG0584	glycerophosphoryl diester phosphodiesterase
AS86_538	COG4641	Protein conserved in bacteria
AS86_5380	COG3829	transcription factor binding
AS86_5380	COG3290	protein histidine kinase activity
AS86_5381	COG0280	phosphate acetyltransferase
AS86_5382	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AS86_5384	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS86_5385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS86_5386	COG0022	dehydrogenase e1 component
AS86_5387	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS86_5388	COG0772	Belongs to the SEDS family
AS86_5389	COG2323	membrane
AS86_5393	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS86_5394	COG0765	amino acid transport
AS86_5395	COG1126	abc transporter atp-binding protein
AS86_5396	COG4129	membrane
AS86_5397	COG1376	ErfK ybiS ycfS ynhG family protein
AS86_5399	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS86_5400	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS86_5403	COG1285	pathogenesis
AS86_5409	COG1760	l-serine dehydratase
AS86_541	COG1252	NADH dehydrogenase
AS86_5410	COG1760	l-serine dehydratase
AS86_5411	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS86_5412	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_5413	COG0300	oxidoreductase activity
AS86_5422	COG1522	sequence-specific DNA binding
AS86_5424	COG0737	Belongs to the 5'-nucleotidase family
AS86_5427	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS86_5430	COG1073	alpha beta
AS86_5430	COG2226	methyltransferase
AS86_5436	COG0307	riboflavin synthase, alpha
AS86_5437	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS86_5437	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS86_5440	COG1073	alpha beta
AS86_5441	COG0456	acetyltransferase
AS86_5442	COG1609	Transcriptional regulator
AS86_5443	COG2056	Na+-H+ antiporter family
AS86_5444	COG0596	Alpha beta hydrolase
AS86_5446	COG4085	toxin activity
AS86_5446	COG1525	nuclease
AS86_5446	COG0737	Belongs to the 5'-nucleotidase family
AS86_5448	COG0456	acetyltransferase
AS86_5448	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AS86_5449	COG0656	L-ascorbic acid biosynthetic process
AS86_545	COG0277	FAD linked oxidase domain protein
AS86_5450	COG0667	Aldo Keto reductase
AS86_5454	COG1300	Membrane
AS86_5455	COG0735	belongs to the Fur family
AS86_5457	COG4974	Belongs to the 'phage' integrase family
AS86_546	COG0385	Bile acid
AS86_5462	COG0598	Magnesium transport protein CorA
AS86_5465	COG1846	Transcriptional regulator
AS86_5469	COG1131	(ABC) transporter
AS86_5470	COG1725	Transcriptional regulator
AS86_5471	COG1686	Belongs to the peptidase S11 family
AS86_5475	COG0733	neurotransmitter:sodium symporter activity
AS86_548	COG0457	Tetratricopeptide repeat
AS86_5480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AS86_5483	COG0697	spore germination
AS86_5484	COG0561	phosphatase activity
AS86_5485	COG4086	secreted protein
AS86_5486	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AS86_5487	COG0456	acetyltransferase
AS86_5488	COG1547	Domain of unknown function (DUF309)
AS86_5493	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS86_5497	COG3711	transcriptional antiterminator
AS86_5498	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS86_5498	COG1263	PTS System
AS86_5498	COG2190	(PTS) system
AS86_5503	COG0778	Nitroreductase
AS86_5504	COG2203	Gaf domain
AS86_5504	COG2199	diguanylate cyclase activity
AS86_5506	COG2084	Dehydrogenase
AS86_551	COG0604	alcohol dehydrogenase
AS86_5513	COG0436	Aminotransferase
AS86_5514	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AS86_5518	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_5519	COG1695	Transcriptional regulator
AS86_552	COG0640	Transcriptional regulator
AS86_5526	COG0183	Belongs to the thiolase family
AS86_5534	COG3842	ATPase activity
AS86_5535	COG0366	Alpha amylase catalytic
AS86_5537	COG2182	Extracellular solute-binding protein
AS86_5538	COG1175	transmembrane transport
AS86_5539	COG3833	ABC-type maltose transport systems, permease component
AS86_554	COG0584	glycerophosphoryl diester phosphodiesterase
AS86_5540	COG1609	Transcriptional regulator
AS86_5541	COG0436	Aminotransferase
AS86_5543	COG2205	protein histidine kinase activity
AS86_5545	COG3209	COG3209 Rhs family protein
AS86_5549	COG2814	Major facilitator Superfamily
AS86_5558	COG1408	metallophosphoesterase
AS86_5559	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_5560	COG2200	EAL domain
AS86_5563	COG4703	Protein of unknown function (DUF1797)
AS86_5565	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AS86_5567	COG0517	IMP dehydrogenase activity
AS86_5568	COG0583	DNA-binding transcription factor activity
AS86_5572	COG0569	domain protein
AS86_5573	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AS86_5575	COG0561	phosphatase activity
AS86_5578	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS86_5579	COG0022	dehydrogenase e1 component
AS86_5589	COG1982	Orn Lys Arg decarboxylase major
AS86_5593	COG0483	inositol monophosphate 1-phosphatase activity
AS86_5598	COG4896	Protein conserved in bacteria
AS86_560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS86_5600	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AS86_5601	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS86_5603	COG0772	Belongs to the SEDS family
AS86_5604	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AS86_5611	COG3336	cytochrome c oxidase
AS86_5614	COG2340	Cysteine-rich secretory protein family
AS86_5617	COG0406	alpha-ribazole phosphatase activity
AS86_5618	COG3679	Belongs to the UPF0342 family
AS86_5621	COG0742	ribosomal rna small subunit methyltransferase
AS86_5622	COG3314	Sporulation integral membrane protein YlbJ
AS86_5624	COG1752	Esterase of the alpha-beta hydrolase superfamily
AS86_5625	COG3480	Lon protease (S16) C-terminal proteolytic domain
AS86_5627	COG1399	metal-binding, possibly nucleic acid-binding protein
AS86_5631	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS86_5636	COG0768	penicillin binding
AS86_5640	COG0772	Belongs to the SEDS family
AS86_5641	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AS86_5644	COG0849	cell division
AS86_5645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AS86_5647	COG1191	sigma factor activity
AS86_5648	COG1191	sigma factor activity
AS86_5649	COG1873	PFAM PRC-barrel domain
AS86_5651	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AS86_5653	COG0762	integral membrane protein
AS86_5654	COG2302	S4 RNA-binding domain
AS86_5655	COG3599	regulation of cell shape
AS86_5659	COG0564	pseudouridine synthase activity
AS86_566	COG1164	Oligoendopeptidase f
AS86_567	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AS86_5671	COG3069	C4-dicarboxylate transmembrane transporter activity
AS86_5675	COG0006	proline dipeptidase activity
AS86_5677	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AS86_5678	COG1561	YicC-like family, N-terminal region
AS86_5682	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS86_5683	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS86_5686	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS86_5686	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS86_5688	COG0631	protein serine/threonine phosphatase activity
AS86_5689	COG0515	serine threonine protein kinase
AS86_5689	COG2815	serine threonine protein kinase
AS86_5691	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS86_5692	COG1564	THIamine pyrophosphokinase
AS86_5694	COG1302	Protein conserved in bacteria
AS86_5695	COG1461	Dihydroxyacetone kinase
AS86_5696	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AS86_5699	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AS86_570	COG1193	negative regulation of DNA recombination
AS86_5700	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_5703	COG3316	Transposase and inactivated derivatives
AS86_5705	COG0772	Belongs to the SEDS family
AS86_5706	COG0741	lytic transglycosylase activity
AS86_5708	COG0577	efflux transmembrane transporter activity
AS86_5709	COG1136	(ABC) transporter
AS86_5710	COG1278	Cold shock
AS86_5714	COG1329	Transcriptional regulator
AS86_5720	COG0583	DNA-binding transcription factor activity
AS86_5721	COG4122	O-methyltransferase activity
AS86_5722	COG2814	Major facilitator Superfamily
AS86_5723	COG1309	transcriptional regulator
AS86_5727	COG2814	Major facilitator Superfamily
AS86_5731	COG1131	(ABC) transporter
AS86_5732	COG1725	Transcriptional regulator
AS86_5734	COG0561	phosphatase activity
AS86_574	COG0583	DNA-binding transcription factor activity
AS86_5742	COG1349	DNA-binding transcription factor activity
AS86_5769	COG0791	NLP P60 protein
AS86_5769	COG3883	PFAM NLP P60 protein
AS86_580	COG3739	integral membrane protein
AS86_5801	COG1454	alcohol dehydrogenase
AS86_5801	COG1012	belongs to the aldehyde dehydrogenase family
AS86_5805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AS86_5805	COG1328	CTP reductase activity
AS86_5808	COG0426	domain, Protein
AS86_5809	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS86_5810	COG1773	rubredoxin
AS86_5811	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AS86_5814	COG4990	cell redox homeostasis
AS86_5815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS86_5816	COG2116	formate transmembrane transporter activity
AS86_5819	COG0531	amino acid
AS86_582	COG1247	-acetyltransferase
AS86_5822	COG0531	amino acid
AS86_5823	COG0657	acetylesterase activity
AS86_5826	COG1404	Belongs to the peptidase S8 family
AS86_5831	COG2801	Transposase and inactivated derivatives
AS86_5833	COG2070	2-Nitropropane dioxygenase
AS86_5836	COG5002	protein histidine kinase activity
AS86_5837	COG0745	RESPONSE REGULATOR receiver
AS86_5839	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS86_584	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AS86_5841	COG0577	efflux transmembrane transporter activity
AS86_5842	COG1136	(ABC) transporter
AS86_5847	COG0823	Involved in the tonB-independent uptake of proteins
AS86_585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS86_5851	COG3979	chitinase
AS86_5854	COG3604	Transcriptional regulator
AS86_5855	COG2376	Dihydroxyacetone kinase
AS86_5857	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS86_5858	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS86_5860	COG3715	PTS system
AS86_5861	COG3716	PTS system mannose fructose sorbose family IID component
AS86_5863	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_5863	COG3409	Peptidoglycan-binding domain 1 protein
AS86_5864	COG2329	Antibiotic biosynthesis monooxygenase
AS86_5870	COG2843	Capsule synthesis protein
AS86_5871	COG1876	peptidase activity
AS86_5873	COG1396	sequence-specific DNA binding
AS86_5877	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS86_5879	COG2801	Transposase and inactivated derivatives
AS86_5880	COG0756	dUTP diphosphatase activity
AS86_5883	COG3011	Protein conserved in bacteria
AS86_5886	COG0531	amino acid
AS86_5890	COG1476	TRANSCRIPTIONal
AS86_5893	COG0659	secondary active sulfate transmembrane transporter activity
AS86_5897	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AS86_5906	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS86_5906	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS86_5909	COG0584	glycerophosphoryl diester phosphodiesterase
AS86_591	COG2814	Major facilitator Superfamily
AS86_5911	COG3711	transcriptional antiterminator
AS86_5911	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS86_5912	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS86_5912	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS86_5912	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS86_5913	COG1482	cell wall glycoprotein biosynthetic process
AS86_5914	COG5002	protein histidine kinase activity
AS86_5914	COG3850	Histidine kinase
AS86_5915	COG0745	RESPONSE REGULATOR receiver
AS86_5918	COG1136	(ABC) transporter
AS86_592	COG1113	amino acid transport
AS86_5921	COG0833	amino acid
AS86_5922	COG2040	homocysteine
AS86_5924	COG1396	sequence-specific DNA binding
AS86_5927	COG2801	Transposase and inactivated derivatives
AS86_593	COG0604	alcohol dehydrogenase
AS86_5931	COG0667	Aldo Keto reductase
AS86_594	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_5942	COG4974	Belongs to the 'phage' integrase family
AS86_5944	COG2239	Acts as a magnesium transporter
AS86_5945	COG0772	Belongs to the SEDS family
AS86_5946	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AS86_5947	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS86_5948	COG2814	Major facilitator Superfamily
AS86_5949	COG1846	Transcriptional regulator
AS86_5950	COG1846	Transcriptional regulator
AS86_5951	COG2124	cytochrome p450
AS86_5960	COG1091	dTDP-4-dehydrorhamnose reductase activity
AS86_5964	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS86_5965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AS86_5968	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AS86_5970	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_5973	COG0842	Transport permease protein
AS86_5974	COG1131	(ABC) transporter
AS86_5975	COG3754	Rhamnan synthesis protein F
AS86_5990	COG2890	protein-(glutamine-N5) methyltransferase activity
AS86_5996	COG0367	asparagine synthase
AS86_5997	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_6	COG1837	Belongs to the UPF0109 family
AS86_600	COG2072	flavoprotein involved in K transport
AS86_6000	COG0824	Thioesterase
AS86_6001	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AS86_6002	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS86_6004	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_6005	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_6017	COG0741	lytic transglycosylase activity
AS86_6017	COG1196	nuclear chromosome segregation
AS86_6017	COG0739	heme binding
AS86_6021	COG3316	Transposase and inactivated derivatives
AS86_6027	COG1136	(ABC) transporter
AS86_6028	COG0577	efflux transmembrane transporter activity
AS86_6029	COG1349	DNA-binding transcription factor activity
AS86_6030	COG0546	phosphoglycolate phosphatase activity
AS86_6032	COG0768	penicillin binding
AS86_6034	COG1595	DNA-templated transcription, initiation
AS86_606	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_6075	COG0187	DNA topoisomerase II activity
AS86_6076	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS86_608	COG1151	hydroxylamine reductase activity
AS86_6090	COG0358	DNA primase activity
AS86_61	COG0305	Participates in initiation and elongation during chromosome replication
AS86_6134	COG1876	peptidase activity
AS86_6166	COG4193	domain, Protein
AS86_6166	COG5263	repeat protein
AS86_617	COG1191	sigma factor activity
AS86_619	COG0726	polysaccharide deacetylase
AS86_6192	COG3409	Peptidoglycan-binding domain 1 protein
AS86_6192	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_6193	COG3409	Peptidoglycan-binding domain 1 protein
AS86_6193	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_622	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AS86_6223	COG3091	SprT-like family
AS86_623	COG1733	regulation of RNA biosynthetic process
AS86_624	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS86_6240	COG3481	metal-dependent phosphohydrolase, HD sub domain
AS86_625	COG0318	PFAM AMP-dependent synthetase and ligase
AS86_6255	COG0515	serine threonine protein kinase
AS86_6255	COG2815	serine threonine protein kinase
AS86_627	COG0384	phenazine biosynthesis protein PhzF
AS86_632	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_636	COG0673	inositol 2-dehydrogenase activity
AS86_6361	COG0210	DNA helicase
AS86_637	COG2188	Transcriptional regulator
AS86_638	COG1733	regulation of RNA biosynthetic process
AS86_639	COG1393	Belongs to the ArsC family
AS86_6418	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS86_6418	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS86_6423	COG3764	Sortase (surface protein transpeptidase)
AS86_644	COG0814	amino acid
AS86_6449	COG4990	cell redox homeostasis
AS86_6478	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS86_648	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS86_649	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AS86_650	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AS86_651	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS86_652	COG1070	Carbohydrate kinase
AS86_653	COG2706	6-phosphogluconolactonase activity
AS86_6531	COG0617	tRNA 3'-terminal CCA addition
AS86_654	COG3813	Protein conserved in bacteria
AS86_6540	COG2088	sporulation resulting in formation of a cellular spore
AS86_6545	COG1393	Belongs to the ArsC family
AS86_655	COG1357	PFAM Pentapeptide repeats (8 copies)
AS86_6568	COG4474	Belongs to the UPF0398 family
AS86_6578	COG0457	Tetratricopeptide repeat
AS86_658	COG0697	spore germination
AS86_659	COG0789	Transcriptional regulator
AS86_6590	COG1388	LysM domain
AS86_6590	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_6590	COG3409	Peptidoglycan-binding domain 1 protein
AS86_660	COG1253	flavin adenine dinucleotide binding
AS86_6612	COG0629	single-stranded DNA binding
AS86_6614	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AS86_6621	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AS86_6622	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AS86_6625	COG0210	DNA helicase
AS86_6626	COG0756	dUTP diphosphatase activity
AS86_6627	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AS86_6635	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AS86_6636	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AS86_6639	COG5002	protein histidine kinase activity
AS86_6640	COG5002	protein histidine kinase activity
AS86_6645	COG1428	Deoxynucleoside kinase
AS86_666	COG0477	Major facilitator Superfamily
AS86_6670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AS86_668	COG0500	methyltransferase
AS86_6683	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AS86_6685	COG0322	excinuclease ABC activity
AS86_6688	COG2310	stress, protein
AS86_6689	COG2310	stress, protein
AS86_6692	COG0861	Integral membrane protein TerC family
AS86_6694	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AS86_6696	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS86_6697	COG1404	Belongs to the peptidase S8 family
AS86_6701	COG4974	Belongs to the 'phage' integrase family
AS86_6702	COG1780	Probably involved in ribonucleotide reductase function
AS86_6703	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS86_6704	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS86_674	COG0628	permease
AS86_676	COG0180	Tryptophanyl-tRNA synthetase
AS86_678	COG1136	(ABC) transporter
AS86_6797	COG0515	serine threonine protein kinase
AS86_6800	COG1132	(ABC) transporter
AS86_6801	COG1695	Transcriptional regulator
AS86_6804	COG4644	lycopene metabolic process
AS86_681	COG0110	maltose O-acetyltransferase activity
AS86_6812	COG1696	Membrane protein involved in D-alanine export
AS86_6813	COG3209	COG3209 Rhs family protein
AS86_6819	COG2070	2-Nitropropane dioxygenase
AS86_682	COG0738	Major facilitator superfamily
AS86_6820	COG0583	DNA-binding transcription factor activity
AS86_683	COG1940	carbohydrate kinase activity
AS86_6830	COG3316	Transposase and inactivated derivatives
AS86_6837	COG0823	Involved in the tonB-independent uptake of proteins
AS86_684	COG0346	lactoylglutathione lyase activity
AS86_686	COG1051	belongs to the nudix hydrolase family
AS86_6895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AS86_69	COG0582	viral genome integration into host DNA
AS86_690	COG1011	Hydrolase
AS86_695	COG1131	(ABC) transporter
AS86_697	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_70	COG1278	Cold shock
AS86_703	COG0778	Nitroreductase
AS86_704	COG1733	regulation of RNA biosynthetic process
AS86_708	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS86_709	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AS86_71	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AS86_711	COG2356	endonuclease I
AS86_712	COG1288	antiporter activity
AS86_713	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AS86_723	COG2249	NAD(P)H dehydrogenase (quinone) activity
AS86_725	COG2031	fatty acid transporter
AS86_728	COG2814	Major facilitator Superfamily
AS86_729	COG1846	Transcriptional regulator
AS86_732	COG0477	Major facilitator Superfamily
AS86_734	COG2843	Capsule synthesis protein
AS86_735	COG1876	peptidase activity
AS86_740	COG5444	nuclease activity
AS86_751	COG4282	regulation of fungal-type cell wall biogenesis
AS86_762	COG2814	Major facilitator Superfamily
AS86_765	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS86_765	COG3409	Peptidoglycan-binding domain 1 protein
AS86_768	COG2207	Transcriptional regulator
AS86_768	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS86_769	COG0662	Cupin 2, conserved barrel domain protein
AS86_773	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS86_779	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS86_780	COG2808	Putative FMN-binding domain
AS86_781	COG0456	acetyltransferase
AS86_782	COG1846	Transcriptional regulator
AS86_783	COG2364	Membrane
AS86_785	COG3850	Histidine kinase
AS86_785	COG5002	protein histidine kinase activity
AS86_789	COG0577	efflux transmembrane transporter activity
AS86_793	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AS86_797	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AS86_799	COG2814	Major facilitator Superfamily
AS86_806	COG1136	(ABC) transporter
AS86_808	COG0277	FAD linked oxidase domain protein
AS86_816	COG0745	RESPONSE REGULATOR receiver
AS86_821	COG0346	lactoylglutathione lyase activity
AS86_824	COG1522	sequence-specific DNA binding
AS86_825	COG1028	Short-chain dehydrogenase reductase Sdr
AS86_827	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AS86_827	COG3320	Male sterility
AS86_829	COG0825	malonyl-CoA metabolic process
AS86_831	COG1476	TRANSCRIPTIONal
AS86_839	COG0583	DNA-binding transcription factor activity
AS86_841	COG0640	Transcriptional regulator
AS86_842	COG0346	lactoylglutathione lyase activity
AS86_843	COG0798	PFAM Bile acid sodium symporter
AS86_847	COG1121	(ABC) transporter
AS86_848	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS86_849	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS86_850	COG1575	Belongs to the MenA family. Type 1 subfamily
AS86_852	COG0726	polysaccharide deacetylase
AS86_853	COG5609	conserved protein (DUF2294)
AS86_854	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS86_856	COG0288	reversible hydration of carbon dioxide
AS86_857	COG0415	Belongs to the DNA photolyase family
AS86_861	COG1073	alpha beta
AS86_865	COG0598	Magnesium transport protein CorA
AS86_866	COG1846	Transcriptional regulator
AS86_867	COG0583	DNA-binding transcription factor activity
AS86_871	COG1335	isochorismatase
AS86_874	COG0737	Belongs to the 5'-nucleotidase family
AS86_877	COG2124	cytochrome p450
AS86_879	COG1115	amino acid carrier protein
AS86_882	COG4191	Histidine kinase
AS86_883	COG0784	Response regulator, receiver
AS86_884	COG0697	spore germination
AS86_885	COG0531	amino acid
AS86_887	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AS86_888	COG0531	amino acid
AS86_889	COG0322	excinuclease ABC activity
AS86_890	COG2207	Transcriptional regulator
AS86_895	COG5002	protein histidine kinase activity
AS86_899	COG1396	sequence-specific DNA binding
AS86_900	COG0252	asparaginase activity
AS86_901	COG0252	asparaginase activity
AS86_902	COG1027	Aspartate ammonia-lyase
AS86_904	COG1063	alcohol dehydrogenase
AS86_908	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS86_909	COG3848	Pyruvate phosphate dikinase
AS86_909	COG0574	Belongs to the PEP-utilizing enzyme family
AS86_913	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AS86_920	COG1960	acyl-CoA dehydrogenase activity
AS86_922	COG0640	Transcriptional regulator
AS86_925	COG1414	Transcriptional regulator
AS86_926	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS86_927	COG1984	allophanate hydrolase subunit 2
AS86_938	COG5002	protein histidine kinase activity
AS86_941	COG1329	Transcriptional regulator
AS86_951	COG0833	amino acid
AS86_953	COG0730	response to heat
AS86_962	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS86_963	COG0697	spore germination
AS86_964	COG2816	NAD+ diphosphatase activity
AS86_966	COG0456	acetyltransferase
AS86_967	COG2207	Transcriptional regulator
AS86_97	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS86_972	COG1136	(ABC) transporter
AS86_974	COG4884	unkown
AS86_974	COG3831	ATPase activity
AS86_978	COG1846	Transcriptional regulator
AS86_979	COG0778	Nitroreductase
AS86_98	COG0527	aspartate kinase activity
AS86_984	COG5444	nuclease activity
AS86_990	COG0753	catalase activity
AS86_991	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AS86_996	COG0714	Associated with various cellular activities