locus-tag class description BF38_1000 ENOG4105D3Q Sugar transferase BF38_1001 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BF38_1002 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BF38_1003 ENOG4107YJ4 chain length determinant protein BF38_1004 ENOG4105HTX biosynthesis protein BF38_1005 ENOG4107YJ4 chain length determinant protein BF38_1008 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BF38_1009 ENOG4105FRN stage II sporulation protein BF38_1012 ENOG4105DY9 regulatoR BF38_1016 ENOG4106778 Protein of unknown function (DUF1146) BF38_1017 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BF38_1018 ENOG4105C8S subunit m BF38_1019 ENOG4105D65 subunit l BF38_102 ENOG4105G6Z alkaline phosphatase BF38_1024 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BF38_1028 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BF38_1029 ENOG4105BZU Histidine kinase BF38_1039 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BF38_104 ENOG4108MUZ hydrolase BF38_1040 ENOG41062M3 atp synthase BF38_1045 ENOG4108YZG isomerase BF38_1048 ENOG4108VGI doxx family BF38_1049 ENOG4107XC4 flavin reductase domain protein, FMN-binding BF38_1052 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BF38_1054 ENOG4108ZXQ stage ii sporulation protein r BF38_1055 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BF38_1056 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BF38_1059 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BF38_1060 ENOG4105CBT Fructose-1,6-bisphosphatase BF38_1061 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BF38_1068 ENOG4105C1G acyl-Coa dehydrogenase BF38_1069 ENOG4105C1G acyl-Coa dehydrogenase BF38_1070 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BF38_1072 ENOG4105DF6 Fe-S oxidoreductase BF38_1075 ENOG4105BZU Histidine kinase BF38_1079 ENOG4108M15 ABC transporter BF38_1080 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BF38_1082 ENOG4105IIU Aminopeptidase BF38_1086 ENOG4105EMN RNA polymerase sigma factor BF38_1088 ENOG410684U Domain of unknown function (DUF1934) BF38_1092 ENOG4105CYW agmatinase BF38_1094 ENOG4105DXB Major Facilitator superfamily BF38_1095 ENOG4107SWG transcriptional regulator MERR family BF38_1096 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BF38_1097 ENOG4105BZ4 penicillin-binding protein BF38_1098 ENOG4108XFG YwhD family BF38_1099 ENOG4108Z4T Peptidase M50 BF38_11 ENOG4105C3R Methionine synthase BF38_1100 ENOG41069HH 4-oxalocrotonate tautomerase BF38_1101 ENOG4105DCI Phosphohydrolase BF38_1102 ENOG4108MES Periplasmic binding protein BF38_1103 ENOG4105E0A ABC, transporter BF38_1104 ENOG4105EHG Permease protein BF38_1105 ENOG4105DQ5 transport system permease protein BF38_1107 ENOG4108VCI transcription factor, rsfa family BF38_111 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BF38_1110 ENOG4108IJ2 phosphate acetyltransferase BF38_1113 ENOG4108VKI Cell wall hydrolase BF38_1117 ENOG4107SVH Potassium channel protein BF38_1119 ENOG410667J hydrolase BF38_112 ENOG4105MIR Phenylalanine 4-monooxygenase BF38_1120 ENOG4105VCH membrane BF38_1122 ENOG4108TU7 Inherit from COG: (ABC) transporter BF38_1123 ENOG4105CJ1 ABC, transporter BF38_1124 ENOG41090WU lipolytic protein G-D-S-L family BF38_1127 ENOG4105D6E homoserine dehydrogenase BF38_1132 ENOG4108Y4K DNA-binding transcriptional activator BF38_1134 ENOG4105WH1 Two component transcriptional regulator luxr family BF38_1135 ENOG4105BZU Histidine kinase BF38_1136 ENOG4105DWF phosphomethylpyrimidine kinase BF38_1137 ENOG4105BZU Histidine kinase BF38_1138 ENOG4105VCD cytoplasmic protein BF38_1139 ENOG4105D22 carbon starvation protein BF38_114 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BF38_1140 ENOG4105DY9 regulatoR BF38_1141 ENOG41079KZ Major Facilitator Superfamily BF38_1145 ENOG4105EN6 Membrane BF38_1146 ENOG4106YBV Methyl-accepting chemotaxis BF38_1148 ENOG4108S4H thioesterase Superfamily protein BF38_1150 ENOG4105JEU Glycosyl transferase, family 2 BF38_1151 ENOG4105C5H ABC transporter BF38_1155 ENOG4105CKK Glycosyl transferase, family 2 BF38_1156 ENOG41067SE Tetr family transcriptional regulator BF38_1158 ENOG4105E0X reductase BF38_1159 ENOG4106F5Q Membrane BF38_1162 ENOG4105DY9 regulatoR BF38_1163 ENOG4108HRK Histidine kinase BF38_1164 ENOG4107RGD Major Facilitator superfamily BF38_1167 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF38_1169 ENOG4105IW1 AmiS UreI transporter BF38_1171 ENOG4105CMR udp-glucose 4-epimerase BF38_1172 ENOG4108UT2 hemolysin iii BF38_1174 ENOG4105C1J atp-dependent rna helicase BF38_1177 ENOG4105DPN Oligoendopeptidase f BF38_1181 ENOG4105C0H protease BF38_1182 ENOG4105Q2H domain protein BF38_1185 ENOG4105BZU Histidine kinase BF38_1186 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_1192 ENOG4105CDU Replicative dna helicase BF38_1194 ENOG4105BZR domain protein BF38_1195 ENOG4108XMW Membrane BF38_1197 ENOG4108UUM single-stranded DNA-binding protein BF38_1199 ENOG4105C3G gtp-binding protein BF38_1200 ENOG4105VDK protein, conserved in bacteria BF38_1201 ENOG4105D8X mechanosensitive ion channel BF38_1202 ENOG4108ZDA Sporulation protein YyaC BF38_1203 ENOG4105FA0 parb-like partition protein BF38_1204 ENOG4107QJE Chromosome Partitioning Protein BF38_1208 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BF38_1210 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BF38_1214 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BF38_1215 ENOG410848D S4 domain protein YaaA BF38_1219 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF38_122 ENOG4105S6R Iron-hydroxamate transporter permease subunit BF38_1225 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BF38_123 ENOG4108V5C ABC transporter BF38_1232 ENOG4105ZMH deoxynucleoside kinase BF38_1234 ENOG4105GTG Isochorismatase BF38_1235 ENOG4108Z6B deaminase BF38_1236 ENOG4105C6E dna polymerase iii BF38_1240 ENOG41067KS pro-sigma K processing BF38_1248 ENOG4105CXN decarboxylase BF38_125 ENOG4108EKI Dehydrogenase BF38_1250 ENOG4105FA2 dna polymerase iii BF38_1251 ENOG4105MA4 psp1 domain protein BF38_1253 ENOG41060K3 Methyltransferase BF38_1255 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BF38_1256 ENOG4105KRN Transcriptional regulator, abrb family BF38_1258 ENOG4105F8V Hydrolase, tatD family BF38_1259 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BF38_126 ENOG4105C28 cystathionine BF38_1261 ENOG4105XFA sporulation peptidase YabG BF38_1262 ENOG4105W42 Veg protein BF38_1265 ENOG4105DFT pur operon repressor BF38_1266 ENOG4105KME endoribonuclease L-psp BF38_1269 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BF38_1272 ENOG4108JA2 transcriptioN-repair coupling factor BF38_1273 ENOG4108JA2 transcriptioN-repair coupling factor BF38_1274 ENOG4108M14 stage v sporulation protein t BF38_1276 ENOG4108IY2 MazG family BF38_1277 ENOG41082I2 s4 domain protein BF38_1278 ENOG4105VYY sporulation protein yabp BF38_1281 ENOG41060GV RNA binding s1 domain protein BF38_1286 ENOG4108UGV hypoxanthine phosphoribosyltransferase BF38_1287 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BF38_1290 ENOG4105C6T cysteine synthase BF38_1291 ENOG4105CRQ synthase (Component I) BF38_1292 ENOG4105DDQ anthranilate synthase BF38_1293 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BF38_1294 ENOG4105EEI dihydropteroate synthase BF38_1295 ENOG4105KRF dihydroneopterin aldolase BF38_1296 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BF38_1298 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BF38_13 ENOG4105C28 cystathionine BF38_1318 ENOG4108Z0C Uvrb UvrC protein BF38_132 ENOG4107XRG penicillin-binding protein BF38_1321 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BF38_1323 ENOG4105CTP PilT protein domain protein BF38_1327 ENOG4105D7W serine acetyltransferase BF38_1330 ENOG4105C2N RNA methyltransferase TrmH family group 3 BF38_1331 ENOG4105M0M Tetracycline resistance protein BF38_1332 ENOG4105QIV RNA polymerase BF38_1334 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BF38_1339 ENOG4107Y49 methyltransferase BF38_1342 ENOG4105XPM ribosomal protein BF38_135 ENOG4105CFP Peptidase U32 BF38_136 ENOG4105XYU peptidase (U32 family) BF38_1363 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BF38_1368 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BF38_137 ENOG4108VQJ O-methyltransferase BF38_1370 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF38_1372 ENOG41067V7 50S ribosomal protein L36 BF38_1378 ENOG4108JJB ABC transporter BF38_1379 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BF38_138 ENOG4105HHA aminodeoxychorismate lyase BF38_1380 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BF38_1385 ENOG4105D1F ATP-binding protein BF38_1388 ENOG4108NMV polysaccharide deacetylase BF38_14 ENOG4105C28 cystathionine BF38_1405 ENOG4105C8B TIGR00159 family BF38_1406 ENOG4107U5W ybbr family BF38_1408 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BF38_1409 ENOG4108VQT Alpha beta hydrolase fold protein BF38_1411 ENOG4105CMG Carbohydrate kinase BF38_1413 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BF38_1414 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BF38_1422 ENOG4108PSK reductase BF38_1423 ENOG4108UMI ABC transporter, permease BF38_1424 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BF38_1425 ENOG4105D01 (LipO)protein BF38_1426 ENOG4105EE1 crotonyl-CoA reductase BF38_1428 ENOG4105IQ5 FAD linked oxidase domain protein BF38_1431 ENOG4105C2C drug resistance transporter, Bcr CflA BF38_1434 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF38_1435 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF38_1436 ENOG4105C3U ABC transporter BF38_1437 ENOG4108JQ7 (ABC) transporter BF38_144 ENOG4105C02 permease BF38_1442 ENOG4105U5Y Transcriptional regulator BF38_1444 ENOG4108J59 Extracellular solute-binding protein, family 5 BF38_1445 ENOG4108J59 Extracellular solute-binding protein, family 5 BF38_1447 ENOG4105II7 pyrroline-5-carboxylate reductase BF38_1448 ENOG4107XDY Nicotinamide Mononucleotide Transporter BF38_1450 ENOG4105E0C molybdate abc transporter BF38_1451 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF38_1452 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BF38_1459 ENOG4105F6E Acyl-transferase BF38_1463 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BF38_1466 ENOG4108RE7 deoxyribonuclease BF38_1467 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BF38_147 ENOG41060CR BF38_1471 ENOG4105C5H ABC transporter BF38_1472 ENOG4105BZU Histidine kinase BF38_1473 ENOG4105WH1 Two component transcriptional regulator luxr family BF38_1474 ENOG4105CJ1 ABC, transporter BF38_1475 ENOG41090VJ ABC-2 type transporter BF38_1476 ENOG4108KYE ABC-2 type transporter BF38_1479 ENOG4105DEF Extracellular solute-binding protein, family 5 BF38_148 ENOG4105C7H Helicase, RecD TraA family BF38_1481 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF38_1482 ENOG4105C3U ABC transporter BF38_1483 ENOG4108JQ7 (ABC) transporter BF38_1484 ENOG410667J hydrolase BF38_1489 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BF38_1490 ENOG4105ERH Fumarylacetoacetate hydrolase BF38_1493 ENOG4105CPF Cell wall formation (By similarity) BF38_1494 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BF38_1496 ENOG4107ZXI Rhomboid family BF38_1499 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BF38_1500 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF38_1502 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BF38_151 ENOG4105C3J Cysteine desulfurase BF38_1522 ENOG4105K8N protein family UPF0079, ATPase BF38_1523 ENOG41072GX Peptidase M22 Glycoprotease BF38_1524 ENOG410801F ribosomal-protein-alanine acetyltransferase BF38_1525 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BF38_1526 ENOG4105C5H ABC transporter BF38_1529 ENOG4108TYN CAAX amino terminal protease family protein BF38_153 ENOG4105D1H recombination factor protein RarA BF38_1533 ENOG4105C7N Xanthine uracil vitamin C permease BF38_1535 ENOG4105BZU Histidine kinase BF38_154 ENOG4108VCI transcription factor, rsfa family BF38_1541 ENOG4107ZXU DSBA oxidoreductase BF38_1549 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF38_155 ENOG4105CUZ uba thif-type nad fad binding protein BF38_1553 ENOG4108SHN Glycosyl transferase, family 2 BF38_1562 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF38_1567 ENOG4105SX7 Transporter BF38_157 ENOG4105CUT histidyl-tRNA synthetase BF38_1573 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BF38_1574 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BF38_1575 ENOG4105C83 adenylosuccinate lyase BF38_1577 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BF38_1582 ENOG4108V3E phosphoribosylglycinamide formyltransferase BF38_1584 ENOG4105C12 Phosphoribosylglycinamide synthetase BF38_1589 ENOG4105C4R Atp-dependent dna helicase BF38_1595 ENOG4108W2Y isochorismatase BF38_1596 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BF38_1597 ENOG4108UMI ABC transporter, permease BF38_1598 ENOG4105D01 (LipO)protein BF38_1602 ENOG410834F Transcriptional regulator BF38_1603 ENOG4107I77 yiaA/B two helix domain BF38_1607 ENOG4105CBD Diacylglycerol kinase BF38_1608 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BF38_1609 ENOG4108JPW Aminotransferase BF38_161 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BF38_1611 ENOG4105C26 Dehydrogenase BF38_1612 ENOG4105KPY Small multidrug resistance protein BF38_1616 ENOG4105D9N nucleoside BF38_1617 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BF38_1620 ENOG4108W15 Protein of unknown function (DUF1456) BF38_1623 ENOG4105DTQ mandelate racemase muconate lactonizing BF38_1624 ENOG4105DFD Na H antiporter BF38_1629 ENOG4105D3R alkyl hydroperoxide reductase BF38_163 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BF38_1630 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BF38_1632 ENOG4107W7X Aldolase BF38_1633 ENOG4105EHG Permease protein BF38_1634 ENOG4105DQ5 transport system permease protein BF38_1635 ENOG4108V5C ABC transporter BF38_1639 ENOG4106UIA BF38_164 ENOG41076HS cation diffusion facilitator family transporter BF38_1640 ENOG4106UIA BF38_1644 ENOG4105BZU Histidine kinase BF38_1648 ENOG410756H nucleotidyltransferase BF38_165 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BF38_1653 ENOG4105E5Q amino acid AbC transporter BF38_1654 ENOG4105EAB amino acid AbC transporter BF38_1656 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF38_1661 ENOG4105C5B carbamate kinase BF38_1665 ENOG4105CI1 PTS System BF38_167 ENOG4105CKP Polysaccharide Biosynthesis Protein BF38_1671 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BF38_1674 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF38_1677 ENOG4105C5H ABC transporter BF38_168 ENOG4108QG2 Membrane BF38_1684 ENOG41062JF Transcriptional regulator BF38_1688 ENOG4105DEU major facilitator superfamily BF38_1694 ENOG4108N0M stress protein BF38_1695 ENOG4106FN3 tellurium resistance protein BF38_1696 ENOG4106FN3 tellurium resistance protein BF38_1697 ENOG4107TS3 membrane protein, TerC BF38_1698 ENOG4108TTB tellurium resistance protein BF38_170 ENOG4105VIE preprotein translocase, subunit YajC BF38_1702 ENOG4105KJF protein tyrosine phosphatase BF38_1704 ENOG4107U9T Pfam:Ribonuclease_BN BF38_1705 ENOG4105C59 p-type ATPase BF38_1706 ENOG4108IPJ Membrane BF38_1709 ENOG4105C3F Signal peptidase i BF38_1711 ENOG4107ZTW SNARE associated Golgi BF38_1714 ENOG410606W general stress protein BF38_1715 ENOG4105UPD Calcium Proton BF38_1722 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BF38_1723 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BF38_173 ENOG41061AI Protein of unknown function (DUF2905) BF38_1730 ENOG4105CSV Glutaminase BF38_1732 ENOG4108A04 Beta-lactamase BF38_1735 ENOG4105CKK Glycosyl transferase, family 2 BF38_1736 ENOG4107QQG Dehydrogenase BF38_1737 ENOG4105C3I Nad-dependent epimerase dehydratase BF38_1740 ENOG4105F1A Pyruvate formate-lyase BF38_1744 ENOG4105CI2 imidazolone-5-propionate hydrolase BF38_1745 ENOG4105ECP epimerase BF38_1751 ENOG41067AE Membrane-bound metal-dependent hydrolase BF38_1752 ENOG4105CEN a g-specific adenine glycosylase BF38_1753 ENOG4106BXE BF38_1757 ENOG4105BZ1 (ABC) transporter BF38_1758 ENOG4107NBY Membrane BF38_1759 ENOG4105CBC glutamate synthase BF38_176 ENOG4108HUF Transporter BF38_1761 ENOG4108IUW ABC transporter BF38_1765 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BF38_1766 ENOG4105G5W regulator Fur family BF38_1790 ENOG4108JQC penicillin-binding protein 1A BF38_1791 ENOG4107ZQN disulfide bond BF38_1793 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BF38_1795 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BF38_1796 ENOG4105BZU Histidine kinase BF38_1798 ENOG4105CYN Serine protein kinase BF38_18 ENOG4105C5X domain protein BF38_1803 ENOG4105C94 Transporter BF38_1806 ENOG4105DZ6 Band 7 protein BF38_1808 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BF38_1809 ENOG4108V9W transcriptional regulatory protein BF38_1810 ENOG4105D4T Citrate transporter BF38_1814 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BF38_1815 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF38_1816 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BF38_1817 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BF38_1818 ENOG4105BZ7 extracellular solute-binding protein family 1 BF38_1819 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BF38_182 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BF38_1820 ENOG4108STX response regulator BF38_1821 ENOG4105US7 Histidine kinase BF38_1826 ENOG4108MRH transcriptional regulatory protein BF38_1828 ENOG4105C6K Malic enzyme BF38_183 ENOG4108IYU L-aspartate oxidase BF38_1830 ENOG4108UZ3 Transporter BF38_1831 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF38_1833 ENOG4105BZU Histidine kinase BF38_1834 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_1836 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BF38_1837 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BF38_1838 ENOG4108JB9 formate dehydrogenase BF38_1842 ENOG4105CUB amino acid BF38_1844 ENOG4105C59 p-type ATPase BF38_1845 ENOG4105DAP Nicotinate phosphoribosyltransferase BF38_1852 ENOG41073R8 VanW family BF38_1853 ENOG4108KGH TRANSCRIPTIONal BF38_1854 ENOG4105D9N nucleoside BF38_1855 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BF38_1856 ENOG4105C37 (CBS) domain BF38_1857 ENOG4108IJ0 Aspartate ammonia-lyase BF38_1858 ENOG4105DAA L-lactate BF38_186 ENOG4108RPX mosc domain containing protein BF38_1861 ENOG4105DUX Transporter BF38_1862 ENOG4108MES Periplasmic binding protein BF38_1863 ENOG4105DQ5 transport system permease protein BF38_1864 ENOG4108IHU transport system permease protein BF38_1865 ENOG4105E0A ABC, transporter BF38_1867 ENOG4105EXW epimerase dehydratase BF38_1868 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BF38_187 ENOG4105CQC Prephenate dehydratase BF38_1870 ENOG4107T89 von Willebrand factor, type A BF38_1871 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BF38_1872 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF38_1875 ENOG4105BZU Histidine kinase BF38_1876 ENOG4105D5Q Arginine ornithine antiporter BF38_1877 ENOG4107414 GntR family transcriptional regulator BF38_1878 ENOG4105C5Y PTS System BF38_1879 ENOG4105CG3 alpha amylase, catalytic region BF38_1882 ENOG4105E1K spore germination protein BF38_1884 ENOG4105CRN Aminoglycoside phosphotransferase BF38_1885 ENOG4105BZG amino acid carrier protein BF38_1886 ENOG4105CDA abc transporter atp-binding protein BF38_1887 ENOG4105CT1 (ABC) transporter BF38_1888 ENOG4105EAD ABC transporter BF38_1889 ENOG4105DRP amino acid AbC transporter BF38_1890 ENOG4108IQI permease BF38_1895 ENOG4105D29 Helix-turn-helix type 11 domain protein BF38_1896 ENOG4105NAE bifunctional deaminase-reductase domain protein BF38_1897 ENOG4105BZU Histidine kinase BF38_1900 ENOG4105CHH sulfate transporter BF38_1901 ENOG41068KF Universal stress protein BF38_1903 ENOG4105DEF Extracellular solute-binding protein, family 5 BF38_1905 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF38_1906 ENOG4108JQ7 (ABC) transporter BF38_1908 ENOG4105CXY transporter BF38_1909 ENOG41067TZ transcriptional regulator, MarR family BF38_191 ENOG4105EWM Histidine kinase BF38_1910 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF38_1911 ENOG4105ETE Transcriptional regulator (LacI family BF38_1912 ENOG4108RVA ribokinase BF38_1914 ENOG4105C2J ABC transporter BF38_1915 ENOG4105CNN ABC, transporter BF38_1916 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF38_1917 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BF38_1929 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF38_1930 ENOG41069ER domain protein BF38_1931 ENOG4105VZ8 Transcriptional regulator BF38_1932 ENOG4107D63 BF38_1934 ENOG4105DUX Transporter BF38_1938 ENOG4105C85 amino acid BF38_1939 ENOG4105C7N Xanthine uracil vitamin C permease BF38_1942 ENOG4105MA6 gCN5-related N-acetyltransferase BF38_1947 ENOG4105BZ9 Cytochrome C oxidase, subunit I BF38_1948 ENOG4105E2S oxidase) subunit II BF38_1951 ENOG4106CAD Protein of unknown function (DUF3311) BF38_1952 ENOG4105E1V na solute symporter BF38_1955 ENOG4108NHD germination protein BF38_1956 ENOG4105CE1 Ferrous iron transport protein b BF38_1957 ENOG4105CE1 Ferrous iron transport protein b BF38_1958 ENOG4105CE1 Ferrous iron transport protein b BF38_1959 ENOG4105CVA phosphate BF38_196 ENOG4105X36 (ribosomal) protein BF38_1960 ENOG4105C8U phosphate abc transporter BF38_1961 ENOG4105E2Z phosphate ABC transporter (Permease BF38_198 ENOG4105C03 ribonuclease BF38_1988 ENOG41080XQ Signal transduction protein with cbs domains BF38_1992 ENOG4105ETU transcriptional activator (TenA BF38_1994 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF38_1996 ENOG4108VEU Thiamine monophosphate synthase BF38_1997 ENOG41080HI glycine oxidase BF38_20 ENOG4105DKQ ROK family BF38_2000 ENOG4105D06 uba thif-type nad fad binding protein BF38_2001 ENOG4105DWF phosphomethylpyrimidine kinase BF38_201 ENOG4107QMS site-determining protein BF38_2010 ENOG4108INS Transcriptional regulator BF38_2013 ENOG4105C7N Xanthine uracil vitamin C permease BF38_2015 ENOG4108PXI ErfK YbiS YcfS YnhG BF38_2022 ENOG4108B31 Spore germination protein BF38_2026 ENOG4107Y03 Nitroreductase BF38_2027 ENOG4105ED1 spovr family BF38_2029 ENOG4108TCS Glutamyl endopeptidase BF38_2031 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BF38_2032 ENOG4105XTG Pfam:DUF156 BF38_2033 ENOG4105VFE sira family BF38_2034 ENOG4107TPS domain protein BF38_2035 ENOG4105VFE sira family BF38_2036 ENOG41085GJ domain protein BF38_2038 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BF38_2039 ENOG41087NI Sulfite exporter TauE/SafE BF38_204 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BF38_2041 ENOG4108KGH TRANSCRIPTIONal BF38_2042 ENOG4105CZN Potassium uptake protein BF38_2046 ENOG4105EMD TRANSCRIPTIONal BF38_2047 ENOG4105VCP PTS System BF38_2048 ENOG4105VZJ PTS System BF38_205 ENOG4105DFF Rod shape-determining protein mreb BF38_2052 ENOG41069ER domain protein BF38_2053 ENOG4107RBB ABC transporter, permease BF38_2054 ENOG4105C19 ABC transporter BF38_2060 ENOG4105WEF catalase BF38_2067 ENOG4107T5V SNARE associated Golgi BF38_2074 ENOG4105CUB amino acid BF38_2075 ENOG4107RWR Sodium hydrogen exchanger BF38_2077 ENOG4106KNT transcriptional regulator BF38_2085 ENOG4108YXU transcriptional regulator AsnC family BF38_2087 ENOG4105KPY Small multidrug resistance protein BF38_2088 ENOG4105KPY Small multidrug resistance protein BF38_209 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BF38_2093 ENOG4105NF4 modulator of drug activity BF38_2095 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BF38_2096 ENOG4105E5W Transporter BF38_2098 ENOG4107RKG DJ-1/PfpI family BF38_2099 ENOG4105CH6 catalase BF38_210 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BF38_2101 ENOG4105D5Q Arginine ornithine antiporter BF38_2102 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BF38_2104 ENOG4105C26 Dehydrogenase BF38_2105 ENOG4105BZ1 (ABC) transporter BF38_2106 ENOG4105BZ1 (ABC) transporter BF38_2108 ENOG4105DRP amino acid AbC transporter BF38_2109 ENOG4105CDA abc transporter atp-binding protein BF38_2112 ENOG410839P BF38_2119 ENOG4107FQX Alpha-acetolactate decarboxylase BF38_212 ENOG41068KH stage VI sporulation protein D BF38_2123 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF38_2124 ENOG4105D4P Coproporphyrinogen iii oxidase BF38_2127 ENOG4105CHH sulfate transporter BF38_2135 ENOG4106AKK s-layer domain-containing protein BF38_2137 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF38_2138 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF38_214 ENOG4105D52 delta-aminolevulinic acid dehydratase BF38_2141 ENOG4105CGU Enoyl-CoA hydratase BF38_2145 ENOG4105DER m42 family BF38_2149 ENOG4105CTU Proline racemase BF38_2157 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF38_2159 ENOG4108JQ7 (ABC) transporter BF38_2162 ENOG4105CSH Transporter BF38_2164 ENOG4108MRH transcriptional regulatory protein BF38_2171 ENOG4105EYH Exonuclease BF38_2173 ENOG4107QI6 Cysteine desulfurase BF38_2183 ENOG4105CDU Replicative dna helicase BF38_2188 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF38_219 ENOG4105K56 Transcriptional regulator BF38_22 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BF38_2204 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BF38_2210 ENOG4105CMT Dihydroxyacetone kinase BF38_2212 ENOG4105CMT Dihydroxyacetone kinase BF38_2214 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BF38_2227 ENOG4105WN5 stage II sporulation protein BF38_2229 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_223 ENOG4108IUQ atp-dependent protease BF38_2231 ENOG4108MJI response regulator BF38_2232 ENOG4105BZU Histidine kinase BF38_2233 ENOG4105BZU Histidine kinase BF38_2238 ENOG4105K8R UPF0145 protein BF38_2246 ENOG4107VRP DNA repair exonuclease BF38_2247 ENOG4106D4I domain protein BF38_2258 ENOG4108MUZ hydrolase BF38_2262 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BF38_2265 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BF38_2268 ENOG4105EMN RNA polymerase sigma factor BF38_2270 ENOG4105CNI cell division protein FtsW BF38_2273 ENOG4105C57 major facilitator superfamily BF38_2274 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF38_2276 ENOG4105EEM helicase BF38_2277 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF38_2282 ENOG4105K59 histidine triad (HIT) protein BF38_2297 ENOG410905X membrane-flanked domain protein BF38_2298 ENOG4105CKV Membrane BF38_230 ENOG4108QCI YvbH-like oligomerisation region BF38_2307 ENOG410905X membrane-flanked domain protein BF38_2308 ENOG4105CKV Membrane BF38_2309 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BF38_2310 ENOG4105BZ4 penicillin-binding protein BF38_2313 ENOG4105C1Q protoporphyrinogen oxidase BF38_2319 ENOG4105ECB domain protein BF38_2323 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) BF38_2325 ENOG4105D29 Helix-turn-helix type 11 domain protein BF38_2327 ENOG4106AXD BF38_2328 ENOG4108RQ5 Beta-lactamase domain-containing protein BF38_2329 ENOG4105DF9 Lipoate-protein, ligase BF38_2331 ENOG4105CEY Amp-dependent synthetase and ligase BF38_234 ENOG4105M59 Phosphodiesterase, mj0936 family BF38_2340 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BF38_2341 ENOG4107RN3 metallophosphoesterase BF38_2343 ENOG4107TVP HD domain protein BF38_2345 ENOG4108AEY RNA polymerase sigma factor BF38_2346 ENOG41086D8 Transcriptional regulator BF38_235 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BF38_2350 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF38_2354 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BF38_2355 ENOG4105C8Q Methyl-accepting chemotaxis BF38_2359 ENOG4105ZU5 s-layer protein BF38_2360 ENOG4107QP3 malate synthase g BF38_2363 ENOG4105VEQ Cold shock protein BF38_2366 ENOG4105XVF Competence transcription factor BF38_237 ENOG4108XJQ germination protein BF38_2380 ENOG4105ERH Fumarylacetoacetate hydrolase BF38_2385 ENOG4105CAQ asparagine synthetase BF38_2386 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BF38_2387 ENOG4105CH6 catalase BF38_2388 ENOG4105BZU Histidine kinase BF38_239 ENOG4108PCX Major Facilitator BF38_2392 ENOG4105QNR S1 RNA binding domain protein BF38_2397 ENOG4107AYK membrAne BF38_2398 ENOG41073B9 BF38_2400 ENOG4108KP7 hydrolase BF38_2402 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF38_2407 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF38_2408 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BF38_241 ENOG4105KBX Transcriptional regulator, TetR family BF38_2411 ENOG4105C31 Tryptophanyl-tRNA synthetase BF38_2414 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF38_2415 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF38_2417 ENOG4108JQ7 (ABC) transporter BF38_2418 ENOG4105UQX Mate efflux family protein BF38_2422 ENOG4108ZCF integral membrane protein BF38_2424 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF38_2426 ENOG4105DPN Oligoendopeptidase f BF38_2429 ENOG4108Z18 K06886 hemoglobin BF38_2430 ENOG4105MIX Adenylate cyclase BF38_2433 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BF38_2434 ENOG4105EMS pseudouridine synthase BF38_2438 ENOG4105K64 Glycosyl transferase, family 2 BF38_244 ENOG4105PFC Transcriptional regulator BF38_2442 ENOG4107TVC Glycosyl transferase, family 2 BF38_2446 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BF38_2447 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BF38_2449 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BF38_2463 ENOG4105CK7 Sodium proline symporter BF38_2464 ENOG4105CRQ synthase (Component I) BF38_2465 ENOG4105DDQ anthranilate synthase BF38_247 ENOG4105DZC cytosine deaminase BF38_248 ENOG4105DZC cytosine deaminase BF38_2483 ENOG4105C7S Dehydrogenase BF38_2485 ENOG4105VZ8 Transcriptional regulator BF38_249 ENOG4105DEF Extracellular solute-binding protein, family 5 BF38_2496 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) BF38_2498 ENOG4105DZ1 carboxypeptidase BF38_2499 ENOG4105VFR signal peptidase BF38_25 ENOG4108UTW Plays a role in the regulation of phosphate uptake BF38_250 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF38_2505 ENOG4105C26 Dehydrogenase BF38_2507 ENOG4105F38 ABC transporter, permease BF38_2508 ENOG4105D38 putrescine abc transporter BF38_2509 ENOG4107RUE extracellular solute-binding protein family 1 BF38_2511 ENOG4105EYF MMPL domain protein BF38_2513 ENOG4108YBP pseudouridine synthase BF38_2515 ENOG4105K4I Scp-like extracellular BF38_2516 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BF38_2517 ENOG4105CQB FAD linked oxidase domain protein BF38_2520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_2521 ENOG4105BZU Histidine kinase BF38_2522 ENOG4105JXH GntR family transcriptional regulator BF38_2526 ENOG4106A3R peptidase BF38_2528 ENOG4108QTI )-transporter BF38_2529 ENOG4107TS3 membrane protein, TerC BF38_253 ENOG4108JQ7 (ABC) transporter BF38_2530 ENOG4105CZN Potassium uptake protein BF38_2531 ENOG410681C small acid-soluble spore protein BF38_2532 ENOG4108Z7G MaoC domain protein dehydratase BF38_2536 ENOG4105CHR reductase BF38_2538 ENOG4105MWK D-amino acid dehydrogenase, small subunit BF38_254 ENOG4108HRK Histidine kinase BF38_2542 ENOG4105C4Y ABC transporter BF38_2543 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF38_2544 ENOG4107RCV ABC transporter, permease BF38_2548 ENOG4105E98 transcriptional regulator DeoR family BF38_255 ENOG4105DY9 regulatoR BF38_2551 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BF38_2553 ENOG4105PXI polysaccharide deacetylase BF38_2555 ENOG4105BZU Histidine kinase BF38_2556 ENOG41090MY MarR family Transcriptional regulator BF38_2558 ENOG4106DF1 BF38_2560 ENOG4105BZU Histidine kinase BF38_2562 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BF38_2563 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BF38_257 ENOG41067S9 phage shock protein C, PspC BF38_2571 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BF38_2572 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF38_2574 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF38_2575 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF38_2576 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BF38_2577 ENOG4105CZV ABC transporter BF38_2579 ENOG4105CJ1 ABC, transporter BF38_258 ENOG4108JCI Transcriptional regulator BF38_2587 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF38_2588 ENOG4105EA8 2-Nitropropane dioxygenase BF38_2589 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BF38_2591 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BF38_2596 ENOG4105NQC Flavodoxin BF38_26 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BF38_260 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BF38_2603 ENOG4107QMU Mate efflux family protein BF38_2604 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BF38_261 ENOG4108Z40 Transcriptional regulator BF38_2610 ENOG4105CZN Potassium uptake protein BF38_2611 ENOG41063Y9 BF38_2612 ENOG4105KBJ sporulation protein ytfj BF38_2616 ENOG4105CM2 brancheD-chain amino acid aminotransferase BF38_2617 ENOG4105C7K acetolactate synthase BF38_2618 ENOG4108ZP8 Acetolactate synthase small subunit BF38_2619 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BF38_262 ENOG4105RHA ABC transporter, permease BF38_2621 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BF38_263 ENOG4108IUX (ABC) transporter BF38_2633 ENOG4107RVV histidinol phosphate phosphatase, hisj family BF38_2636 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BF38_2637 ENOG4105E0M Sulfatase BF38_2639 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BF38_264 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BF38_2643 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BF38_2644 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BF38_2646 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BF38_2647 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BF38_2648 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BF38_2649 ENOG4105C8J )-transporter BF38_265 ENOG4105ER2 Ompa motb domain protein BF38_2653 ENOG4105DFD Na H antiporter BF38_2657 ENOG4105ENE Histidine kinase BF38_2658 ENOG4105WH1 Two component transcriptional regulator luxr family BF38_266 ENOG4105E14 MotA TolQ exbB proton channel BF38_2662 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BF38_267 ENOG4108VXD carboxy-peptidase BF38_2671 ENOG4105CJ3 phosphate transporter BF38_2672 ENOG4107GRR phosphate transport regulator BF38_2673 ENOG4105BZ4 penicillin-binding protein BF38_2676 ENOG4105BZU Histidine kinase BF38_2677 ENOG4105I3N Conserved Protein BF38_2680 ENOG4105BZU Histidine kinase BF38_2687 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF38_2688 ENOG4105DZ1 carboxypeptidase BF38_2689 ENOG4108JIC nucleoside recognition domain protein BF38_269 ENOG4105E33 succinate dehydrogenase BF38_2691 ENOG4105FE9 pseudouridine synthase BF38_2693 ENOG4107TWT Cytochrome c biogenesis protein BF38_2694 ENOG4105CRE cytochrome C BF38_2695 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_2696 ENOG4105BZU Histidine kinase BF38_2697 ENOG4108WBT adenosyltransferase BF38_2698 ENOG41063SB peptidase BF38_27 ENOG4105E2Z phosphate ABC transporter (Permease BF38_2700 ENOG4108SAX Membrane BF38_2703 ENOG4105C9U ATP-dependent DNA helicase RecQ BF38_2704 ENOG4105I7S Abortive infection protein BF38_2706 ENOG4107RGJ metallophosphoesterase BF38_2707 ENOG4107X2D transcriptional regulator, merr family BF38_2708 ENOG4108S6Z Negative regulator of genetic competence BF38_271 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BF38_2713 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BF38_2714 ENOG4107RB3 L-asparaginase BF38_2721 ENOG4105S2F BF38_2722 ENOG41065D1 BF38_2728 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BF38_2731 ENOG4105XXQ heptaprenyl diphosphate synthase component I BF38_2733 ENOG4105EAH synthase BF38_2737 ENOG4105CIH Imidazole acetol-phosphate transaminase BF38_2738 ENOG41068YB TPR repeat-containing protein BF38_274 ENOG4105K63 Thioredoxin BF38_2741 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BF38_2742 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BF38_2743 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BF38_2749 ENOG4108JYZ YitT family BF38_275 ENOG4105C10 Electron transfer flavoprotein BF38_2750 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BF38_2753 ENOG4105FJR Lmbe family BF38_2754 ENOG4105CPK Glycosyl transferase (Group 1 BF38_276 ENOG4105BZJ Electron transfer flavoprotein BF38_2761 ENOG4105DVT helicase BF38_2762 ENOG4105YAC BF38_2766 ENOG4105CSM endonuclease III BF38_2768 ENOG4105BZ4 penicillin-binding protein BF38_277 ENOG41060WC Enoyl-CoA hydratase BF38_2779 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BF38_278 ENOG4107Z3H Transcriptional regulator, TetR family BF38_2781 ENOG4105DVT helicase BF38_2782 ENOG4105CTD carboxy-peptidase BF38_2785 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF38_2787 ENOG4105C2W permease BF38_2788 ENOG4105DHF Membrane BF38_279 ENOG4105CEY Amp-dependent synthetase and ligase BF38_2790 ENOG410890F Dynamin family BF38_2792 ENOG4108W0I acetyltransferase BF38_2794 ENOG4105KHC sulfurtransferase BF38_2797 ENOG4106032 Glutathionylspermidine synthase BF38_28 ENOG4105C8U phosphate abc transporter BF38_2809 ENOG4105CPK Glycosyl transferase (Group 1 BF38_281 ENOG4105J76 Periplasmic binding protein BF38_2813 ENOG4108SZE gCN5-related N-acetyltransferase BF38_2817 ENOG41081VK Ribonuclease BF38_282 ENOG4105S6R Iron-hydroxamate transporter permease subunit BF38_2830 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF38_2832 ENOG4107RWR Sodium hydrogen exchanger BF38_2833 ENOG4105CN5 Metallo-Beta-Lactamase BF38_2834 ENOG4108Z5V transcriptional regulator, merr family BF38_2836 ENOG4105H67 Protein of unknown function (DUF421) BF38_2837 ENOG41080C8 DUF218 domain BF38_2848 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BF38_2850 ENOG4107R0U MotA TolQ exbB proton channel BF38_2851 ENOG4105ER2 Ompa motb domain protein BF38_2852 ENOG4107YTP response regulator receiver protein BF38_2853 ENOG4105CBS Chea signal transduction histidine kinase BF38_2854 ENOG4105DD5 Flagellar motor switch protein BF38_2857 ENOG4105BZU Histidine kinase BF38_2861 ENOG4105E1Q flagellar hook-associated protein BF38_2862 ENOG4105DTJ flagellar hook-associated protein BF38_2863 ENOG4107TPX flagellar hook-associated BF38_2866 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BF38_2867 ENOG4108ZC9 flagellar basal-body rod protein flgc BF38_2868 ENOG41075Z6 flagellar hook-basal body complex protein fliE BF38_2869 ENOG4107U2N Flagellar M-ring protein BF38_2870 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF38_2876 ENOG4105BZE flagellar hook protein, FlgE BF38_2879 ENOG4107R88 Chemotaxis protein (CheV) BF38_2881 ENOG4105I03 Flagellin BF38_2882 ENOG4105I03 Flagellin BF38_2883 ENOG4105E4C Lytic transglycosylase catalytic BF38_2885 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF38_2886 ENOG4105DD5 Flagellar motor switch protein BF38_2888 ENOG4105CN7 Flagellar biosynthetic protein FliP BF38_2889 ENOG4105VS8 Flagellar biosynthetic protein fliq BF38_2891 ENOG4105D00 flagellar biosynthetic protein flhB BF38_2892 ENOG4105D7B Flagellar biosynthesis protein flha BF38_2893 ENOG4105FZW flagellar biosynthesis regulator FlhF BF38_2894 ENOG4105KTQ flagellar basal-body rod protein BF38_2895 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BF38_29 ENOG4105PWN phosphate abc transporter BF38_290 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF38_2902 ENOG4105KAC Antibiotic biosynthesis monooxygenase BF38_2907 ENOG4105DUM transcriptional regulator, lysR family BF38_2908 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF38_2909 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF38_2910 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BF38_2911 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BF38_2922 ENOG4105K56 Transcriptional regulator BF38_2924 ENOG4105CAQ asparagine synthetase BF38_2928 ENOG4105PGM cation diffusion facilitator family transporter BF38_293 ENOG4105DR4 Methyltransferase BF38_2930 ENOG4105DRR Transcriptional regulator, GntR family BF38_2931 ENOG4108UZ3 Transporter BF38_2932 ENOG4105CKI cobalamin synthesis protein BF38_2933 ENOG4108PJD permease BF38_2936 ENOG4105DFD Na H antiporter BF38_2937 ENOG4105VUF Transcriptional regulator BF38_2939 ENOG4105C9Q fumarate hydratase class II BF38_2943 ENOG4107QJQ Mate efflux family protein BF38_2944 ENOG4105EC3 peptidase S51, dipeptidase E BF38_2948 ENOG4107QIV Cytochrome c biogenesis protein BF38_2954 ENOG4106BRA Membrane BF38_296 ENOG4105KFN sortase, SrtB family BF38_2961 ENOG4105CJ1 ABC, transporter BF38_2965 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BF38_2967 ENOG4108IJ0 Aspartate ammonia-lyase BF38_2968 ENOG4105C6K Malic enzyme BF38_297 ENOG4105E0A ABC, transporter BF38_2980 ENOG4105FVX BF38_2988 ENOG4105CSR polyphosphate kinase 2 BF38_2989 ENOG4105DXI Major Facilitator superfamily BF38_2992 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF38_2994 ENOG4105EU0 Major facilitator Superfamily BF38_2995 ENOG4105C6T cysteine synthase BF38_2999 ENOG4105C8J )-transporter BF38_30 ENOG4107RF6 penicillin-binding protein BF38_300 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BF38_3001 ENOG4105X5K response regulator receiver protein BF38_3002 ENOG4105H67 Protein of unknown function (DUF421) BF38_3006 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BF38_3007 ENOG4105CHR reductase BF38_3008 ENOG4105CM2 brancheD-chain amino acid aminotransferase BF38_3009 ENOG4105C7K acetolactate synthase BF38_3010 ENOG4108ZP8 Acetolactate synthase small subunit BF38_3011 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BF38_3013 ENOG4105C7B Threonine dehydratase BF38_3018 ENOG4105C6X Major Facilitator BF38_3019 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BF38_302 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BF38_3021 ENOG4105DY9 regulatoR BF38_3022 ENOG4105CYC Transferase BF38_3026 ENOG4105F6J Alpha beta hydrolase fold BF38_3027 ENOG4105VTR Integrase BF38_304 ENOG4105FE9 pseudouridine synthase BF38_3051 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BF38_3059 ENOG410900G Protein of unknown function (DUF421) BF38_3061 ENOG4105CNU cell division protein FtsK BF38_307 ENOG4105DCG PHP domain protein BF38_3070 ENOG4105CAR Terminase, large subunit BF38_3073 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BF38_3085 ENOG4105XSJ toxin secretion phage lysis holin BF38_3098 ENOG41068WN BF38_3102 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BF38_3103 ENOG4105C72 UPF0176 protein BF38_3105 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BF38_3107 ENOG4105C0X amino acid BF38_3112 ENOG4107RHR regulatoR BF38_3114 ENOG4105D9N nucleoside BF38_3115 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BF38_3121 ENOG4107RAQ aminopeptidase BF38_3122 ENOG4107R16 Multicopper oxidase BF38_3132 ENOG4108T5E Copper resistance protein BF38_3133 ENOG4105KTB nuclear export factor GLE1 BF38_3134 ENOG4107RT3 EamA-like transporter family BF38_3135 ENOG4105GZI Transcriptional regulator BF38_3136 ENOG4108Z40 Transcriptional regulator BF38_3137 ENOG4107ZXU DSBA oxidoreductase BF38_3138 ENOG4108TVJ Nitroreductase BF38_314 ENOG4105C5S asparaginyl-tRNA synthetase BF38_3140 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BF38_3141 ENOG4106F5Q Membrane BF38_3142 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF38_3144 ENOG4105CKI cobalamin synthesis protein BF38_3148 ENOG4108Z7G MaoC domain protein dehydratase BF38_3149 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF38_315 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BF38_3151 ENOG4105C0Z ABC transporter BF38_3152 ENOG4108IV0 ABC, transporter BF38_3153 ENOG4105C32 Amino acid ABC transporter (Permease) BF38_3155 ENOG4105SKE transcriptional Regulator LysR family BF38_3157 ENOG4105MDS 4-oxalocrotonate tautomerase BF38_3161 ENOG4105C4M (Ubiquinol oxidase) subunit I BF38_3162 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF38_3163 ENOG4108JJ9 ABC, transporter BF38_3164 ENOG4108JJ8 (ABC) transporter BF38_3167 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF38_317 ENOG4108RWN rrna methyltransferase BF38_3172 ENOG4105BZ1 (ABC) transporter BF38_3173 ENOG4105EFI regulatoR BF38_3174 ENOG4105BZU Histidine kinase BF38_3177 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BF38_3178 ENOG4108ZJ4 polysaccharide deacetylase BF38_3179 ENOG4106AKJ BF38_3182 ENOG4105D6E homoserine dehydrogenase BF38_3187 ENOG4108KGH TRANSCRIPTIONal BF38_3189 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF38_3190 ENOG4105BZU Histidine kinase BF38_3191 ENOG4107VMI polysaccharide deacetylase BF38_3193 ENOG4105KT7 mgtC SapB transporter BF38_3194 ENOG4105VRR gCN5-related N-acetyltransferase BF38_3196 ENOG4105DUU IucA IucC family protein BF38_3197 ENOG4105CEY Amp-dependent synthetase and ligase BF38_32 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF38_3200 ENOG4108WBH protein TIM barrel BF38_3201 ENOG4105YWU small acid-soluble spore protein BF38_3203 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BF38_3213 ENOG4105KRN Transcriptional regulator, abrb family BF38_3217 ENOG4105YVS arsR family transcriptional regulator BF38_3218 ENOG4107SET aldo keto reductase BF38_3219 ENOG4107XZQ multidrug resistance protein BF38_3224 ENOG4105C8Q Methyl-accepting chemotaxis BF38_3227 ENOG4108K88 Membrane BF38_3228 ENOG4108WPJ Ferritin-like domain BF38_3231 ENOG4105DEN Luciferase family BF38_3235 ENOG4107QM2 Aldo Keto reductase BF38_3236 ENOG4105CKI cobalamin synthesis protein BF38_324 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF38_3247 ENOG4105DSE periplasmic solute binding protein BF38_3249 ENOG4105K4T epimerase BF38_325 ENOG4105CW7 secretion protein, HlyD family BF38_3251 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BF38_3256 ENOG4107TB6 phosphoglycerate mutase BF38_326 ENOG4108JGH Tetr family transcriptional regulator BF38_3260 ENOG4107T5V SNARE associated Golgi BF38_3263 ENOG4108PJD permease BF38_3265 ENOG4108S4H thioesterase Superfamily protein BF38_3266 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BF38_327 ENOG4105CN9 Peptidase m42 family protein BF38_3270 ENOG4105SXS Protein of unknown function (DUF456) BF38_3271 ENOG4105C37 (CBS) domain BF38_3275 ENOG4108Z7R Chaperone CsaA BF38_3279 ENOG4108ZRV stage ii sporulation protein p BF38_3281 ENOG4108VXD carboxy-peptidase BF38_3283 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BF38_3288 ENOG4108X4Q Hydrolase BF38_3290 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF38_3291 ENOG4107RBS Methyltransferase BF38_3294 ENOG41087PP glycosyltransferase MGT family BF38_3295 ENOG4108JYZ YitT family BF38_3296 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF38_3302 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BF38_331 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BF38_3315 ENOG4105KBJ sporulation protein ytfj BF38_332 ENOG4105C22 threonyL-tRNA synthetase BF38_3320 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BF38_3324 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BF38_3325 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BF38_3327 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BF38_3328 ENOG4105EMN RNA polymerase sigma factor BF38_333 ENOG4108TDW sporulation protein YtxC BF38_3330 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BF38_3334 ENOG4108V06 Glutathione peroxidase BF38_3337 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF38_3339 ENOG4108IUE nitrate reductase beta subunit BF38_3340 ENOG4105R3A Nitrate reductase BF38_3343 ENOG4108Z40 Transcriptional regulator BF38_3344 ENOG4105K63 Thioredoxin BF38_3345 ENOG4107QN2 dihydrolipoyl dehydrogenase BF38_3346 ENOG4106HZJ BF38_3347 ENOG4108X3M OsmC Ohr family protein BF38_3348 ENOG4105D3W isochorismatase BF38_3351 ENOG4107V6Q Cyclic nucleotide-binding domain BF38_3352 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BF38_3353 ENOG4105D06 uba thif-type nad fad binding protein BF38_3354 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF38_3355 ENOG4108ZAF Molybdopterin BF38_3359 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BF38_3360 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BF38_3361 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BF38_3362 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BF38_3363 ENOG4108IFG nitrite reductase, (NAD(P)H) BF38_3364 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BF38_337 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BF38_3371 ENOG4105MCT stage V sporulation protein S BF38_3376 ENOG4105C5H ABC transporter BF38_3379 ENOG4108UUM single-stranded DNA-binding protein BF38_338 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BF38_3383 ENOG4107YX5 Pfam:DUF548 BF38_3384 ENOG4105C75 arginyL-tRNA synthetase BF38_339 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BF38_3392 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BF38_3393 ENOG4105C5S asparaginyl-tRNA synthetase BF38_3397 ENOG4105EC2 ftsk spoIIIe BF38_341 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BF38_3415 ENOG4105BZW Glycerate kinase BF38_3416 ENOG4107QPK )-transporter BF38_3417 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_3418 ENOG41062D9 Histidine kinase BF38_342 ENOG4105C2M dna polymerase I BF38_3421 ENOG4105C8J )-transporter BF38_3425 ENOG4107XGZ Hydrolase BF38_3426 ENOG4105CY2 Citrate transporter BF38_3427 ENOG4105C0A alcohol dehydrogenase BF38_343 ENOG4105BZU Histidine kinase BF38_3430 ENOG4105KD7 acetyltransferase BF38_3431 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BF38_3436 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BF38_3439 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BF38_344 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF38_3442 ENOG4107RVG penicillin-binding protein BF38_3444 ENOG4105E9Q Acyl-transferase BF38_3445 ENOG4108UT2 hemolysin iii BF38_3447 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BF38_3449 ENOG4108RCR degv family BF38_3450 ENOG4105E8R UPF0173 metal-dependent hydrolase BF38_3451 ENOG4108KF3 Electron transport protein SCO1 SenC BF38_3452 ENOG4107Y70 Heat shock protein BF38_3453 ENOG4105CAQ asparagine synthetase BF38_3457 ENOG4108MES Periplasmic binding protein BF38_3458 ENOG4105F0I Aminotransferase BF38_3464 ENOG4107Y70 Heat shock protein BF38_3465 ENOG4105D8X mechanosensitive ion channel BF38_3466 ENOG4105BZU Histidine kinase BF38_3467 ENOG4105WH1 Two component transcriptional regulator luxr family BF38_3469 ENOG4106KNT transcriptional regulator BF38_3475 ENOG4105CMG Carbohydrate kinase BF38_3476 ENOG4105CMG Carbohydrate kinase BF38_3482 ENOG4108IJ8 ABC transporter BF38_3483 ENOG4105E90 ABC transporter BF38_349 ENOG4108HMX isocitrate dehydrogenase (NADP) BF38_3490 ENOG4105C37 (CBS) domain BF38_3495 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF38_3498 ENOG4107S4Y M20 DapE family protein YgeY BF38_3499 ENOG4108TSC N-acetyltransferase BF38_350 ENOG4105BZN citrate synthase BF38_3500 ENOG4108JUB Transcriptional regulator BF38_3501 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BF38_3509 ENOG4108N23 SpoOM-related protein BF38_3511 ENOG410841Q phosphoesterase PA-phosphatase related protein BF38_3512 ENOG4105SZ6 Thioredoxin BF38_3514 ENOG4108IBT Inherit from COG: transposase BF38_352 ENOG4108REF Sporulation integral membrane protein ytvi BF38_3527 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BF38_353 ENOG4105FS0 cytoplasmic membrane protein BF38_3535 ENOG4105BZ4 penicillin-binding protein BF38_3536 ENOG4105CZM Major Facilitator BF38_3537 ENOG4105W8X HesB YadR YfhF-family protein BF38_3539 ENOG4105DXD 2-methylcitrate dehydratase BF38_3540 ENOG4105CR4 methylisocitrate lyase BF38_3541 ENOG4105C1G acyl-Coa dehydrogenase BF38_3542 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BF38_3544 ENOG4105N14 lysine exporter protein LysE YggA BF38_3545 ENOG4105E39 Enoyl-CoA hydratase BF38_3548 ENOG4107RFY SbcCD D subunit BF38_3549 ENOG4105EYH Exonuclease BF38_3552 ENOG4105FCD Major Facilitator BF38_3553 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BF38_3554 ENOG4105E4F Isochorismate synthase BF38_3555 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BF38_3556 ENOG4105WQI isochorismatase BF38_3557 ENOG4105CEY Amp-dependent synthetase and ligase BF38_3558 ENOG4105WQT MbtH domain protein BF38_3559 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF38_3562 ENOG4105K70 DNA-binding protein BF38_3566 ENOG4105BZG amino acid carrier protein BF38_3570 ENOG4105FE9 pseudouridine synthase BF38_3571 ENOG4105C22 threonyL-tRNA synthetase BF38_3572 ENOG4105C19 ABC transporter BF38_3574 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BF38_3578 ENOG4108D32 Methyltransferase BF38_358 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BF38_3582 ENOG41081I9 integral membrane protein BF38_3585 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BF38_3587 ENOG4105EYF MMPL domain protein BF38_359 ENOG4105C6K Malic enzyme BF38_3591 ENOG4105WCN acetyltransferase BF38_3597 ENOG4105C1Q protoporphyrinogen oxidase BF38_3599 ENOG41068WN BF38_360 ENOG4105C0B DNA polymerase III (alpha subunit) BF38_3601 ENOG4105VEQ Cold shock protein BF38_3605 ENOG410667J hydrolase BF38_361 ENOG4105VV2 BF38_3612 ENOG4107V2S Transcriptional regulator BF38_3613 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF38_3616 ENOG4107RSM transcriptional regulator BF38_3617 ENOG4108RPX mosc domain containing protein BF38_3620 ENOG4105BZ1 (ABC) transporter BF38_3621 ENOG4105BZ1 (ABC) transporter BF38_3625 ENOG4108JCI Transcriptional regulator BF38_363 ENOG4105SFS phosphoesterase RecJ domain protein BF38_3632 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BF38_3635 ENOG4108KPJ rna polymerase sigma factor BF38_3641 ENOG4105F32 YngK protein BF38_3646 ENOG4105RD7 BadF BadG BcrA BcrD BF38_3648 ENOG4107STF Involved in phosphonate degradation (By similarity) BF38_3653 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BF38_3656 ENOG4105C1J atp-dependent rna helicase BF38_3658 ENOG4108RZE Tetr family transcriptional regulator BF38_3670 ENOG4105VTR Integrase BF38_3675 ENOG41088CC tellurite resistance protein tehB BF38_3677 ENOG4108I0C methyltransferase BF38_3678 ENOG4107RA9 decarboxylase BF38_3679 ENOG41090HR transcriptional regulator BF38_3685 ENOG4105CIN aminoacyl-histidine dipeptidase BF38_3691 ENOG4107RF6 penicillin-binding protein BF38_3692 ENOG4107RF6 penicillin-binding protein BF38_3694 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BF38_3695 ENOG4105ETE Transcriptional regulator (LacI family BF38_3696 ENOG4105IE8 Alpha-ketoglutarate permease BF38_3697 ENOG4105CK5 oxidoreductase BF38_37 ENOG4105N80 Ferric uptake regulator, Fur family BF38_370 ENOG4105DC7 peptidase M24 BF38_3702 ENOG4105D2N Aldolase BF38_3703 ENOG4105DH8 myo-inositol catabolism BF38_3706 ENOG4105CGH 5'-nucleotidase BF38_3709 ENOG4105VZ8 Transcriptional regulator BF38_3712 ENOG4108VXD carboxy-peptidase BF38_3715 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity BF38_3716 ENOG41067SE Tetr family transcriptional regulator BF38_3717 ENOG4105C5H ABC transporter BF38_3718 ENOG4105BZU Histidine kinase BF38_3720 ENOG4105CEP NADH dehydrogenase BF38_3721 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BF38_3724 ENOG4105CJ1 ABC, transporter BF38_3726 ENOG4107Z3H Transcriptional regulator, TetR family BF38_3729 ENOG4105C1G acyl-Coa dehydrogenase BF38_3730 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BF38_3731 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BF38_3732 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BF38_3733 ENOG4105E39 Enoyl-CoA hydratase BF38_3734 ENOG4107QX3 carboxylase BF38_3735 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BF38_3737 ENOG4105WCN acetyltransferase BF38_3738 ENOG4105DBI uridine monophosphokinase BF38_3741 ENOG4105DZ1 carboxypeptidase BF38_3744 ENOG4105T9C HD domain BF38_3746 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BF38_375 ENOG4105D7V transposase BF38_3757 ENOG4105FQP Beta-lactamase BF38_3759 ENOG4107Y80 Major Facilitator superfamily BF38_3763 ENOG4105CUV Homoserine Kinase BF38_3770 ENOG4105CPQ Dehydrogenase BF38_3774 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BF38_3776 ENOG4105DK7 lysyl-tRNA synthetase BF38_379 ENOG4105Z7P Acetyltransferase (GNAT) family BF38_3793 ENOG4105ETU transcriptional activator (TenA BF38_380 ENOG41082W1 Cupin 2, conserved barrel domain protein BF38_3814 ENOG410667J hydrolase BF38_3815 ENOG4105BZU Histidine kinase BF38_3816 ENOG4107RF6 penicillin-binding protein BF38_382 ENOG4105VZ8 Transcriptional regulator BF38_3823 ENOG4108HGU Histidine kinase BF38_3826 ENOG4105CB2 alcohol dehydrogenase BF38_3827 ENOG4105CJN penicillin-binding protein BF38_3829 ENOG4105FQP Beta-lactamase BF38_3835 ENOG4108V4B ThiJ pfpI BF38_3841 ENOG4107Y80 Major Facilitator superfamily BF38_3845 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BF38_3849 ENOG4107Y9U Membrane BF38_3857 ENOG4105FCD Major Facilitator BF38_386 ENOG4107YZX Universal stress protein BF38_3860 ENOG4105E09 nadh pyrophosphatase BF38_3861 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BF38_3862 ENOG4108Z4K mutator MutT protein BF38_3870 ENOG4108XI2 Domain of unknown function (DUF1963) BF38_3874 ENOG4108NRW Phospholipase, patatin family BF38_3875 ENOG4105KWG Pfam:DUF1696 BF38_3882 ENOG4105PKS Excinuclease abc c subunit domain protein BF38_3890 ENOG4107VFR oxidoreductase BF38_3895 ENOG4105U0R haloacid dehalogenase-like hydrolase BF38_39 ENOG4105FDK ABC transporter BF38_3900 ENOG4105DY8 decarboxylase BF38_3903 ENOG4108IUM Glycogen debranching enzyme BF38_3908 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BF38_3910 ENOG4105FDR Membrane BF38_3922 ENOG4105MSI germination protein ypeb BF38_3929 ENOG4107Z3H Transcriptional regulator, TetR family BF38_3935 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BF38_3939 ENOG4105E98 transcriptional regulator DeoR family BF38_3944 ENOG4107QKR Dehydrogenase BF38_3946 ENOG4107RUY (E1 component), alpha subunit BF38_3948 ENOG4105E1F short-chain dehydrogenase reductase BF38_3949 ENOG4105RHY Pfam:UPF0157 BF38_395 ENOG4108JYZ YitT family BF38_3950 ENOG4105DBI uridine monophosphokinase BF38_3956 ENOG4107SQ8 Glycine betaine BF38_3957 ENOG4108IJ7 Glycine betaine BF38_3963 ENOG41082BV acetyltransferase BF38_3964 ENOG4108M1A Chitin-binding protein BF38_3968 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF38_3972 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BF38_3978 ENOG4108Z7F N-acetyltransferase BF38_3982 ENOG4105EEM helicase BF38_3986 ENOG4105C9U ATP-dependent DNA helicase RecQ BF38_3995 ENOG4108M1A Chitin-binding protein BF38_3998 ENOG4105BZG amino acid carrier protein BF38_3999 ENOG4105C26 Dehydrogenase BF38_40 ENOG4108JYZ YitT family BF38_4000 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BF38_4001 ENOG4105CTU Proline racemase BF38_4002 ENOG4105CTU Proline racemase BF38_4003 ENOG41080HI glycine oxidase BF38_4005 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BF38_401 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BF38_4011 ENOG4107T5V SNARE associated Golgi BF38_4014 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BF38_4015 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BF38_4018 ENOG4105DTQ mandelate racemase muconate lactonizing BF38_402 ENOG4105KBJ sporulation protein ytfj BF38_4025 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BF38_4026 ENOG4105BZU Histidine kinase BF38_4027 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_4034 ENOG4105DPN Oligoendopeptidase f BF38_4036 ENOG4105EPR degv family BF38_4044 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BF38_4045 ENOG4106K7D Major facilitator family transporter BF38_4049 ENOG4107BMA Transglycosylase associated protein BF38_405 ENOG4105EFZ amidohydrolase BF38_4052 ENOG41089UC methyltransferase, type 11 BF38_4059 ENOG4105CHM Aminotransferase BF38_4062 ENOG4108ZMI UPF0477 protein BF38_4065 ENOG4105DVE abc transporter atp-binding protein BF38_407 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BF38_4074 ENOG4105C02 permease BF38_4076 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BF38_4077 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BF38_4078 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BF38_4083 ENOG4105E09 nadh pyrophosphatase BF38_4087 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BF38_4097 ENOG4107VC0 DNA alkylation repair enzyme BF38_41 ENOG41069ZM Protein of unknown function (DUF2624) BF38_4101 ENOG4108ZCF integral membrane protein BF38_4102 ENOG4105E0M Sulfatase BF38_4103 ENOG4105C5H ABC transporter BF38_4105 ENOG4105EYF MMPL domain protein BF38_4106 ENOG41082JN Transcriptional regulator BF38_4110 ENOG4105CIH Imidazole acetol-phosphate transaminase BF38_4112 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BF38_4119 ENOG41069ER domain protein BF38_412 ENOG4106KR7 LysR family Transcriptional regulator BF38_4121 ENOG4105CY2 Citrate transporter BF38_4122 ENOG4105E39 Enoyl-CoA hydratase BF38_4123 ENOG4105J5T Amp-dependent synthetase and ligase BF38_4124 ENOG4108JUB Transcriptional regulator BF38_4128 ENOG4105D4B ABC, transporter BF38_4130 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BF38_4132 ENOG4105DKT Transcriptional regulator BF38_4133 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BF38_4135 ENOG41061GT Aldolase BF38_4139 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BF38_414 ENOG4105U5Y Transcriptional regulator BF38_4145 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BF38_4146 ENOG4105II7 pyrroline-5-carboxylate reductase BF38_4150 ENOG4107258 Transcriptional regulator BF38_4152 ENOG4105E0Y RtcB Protein BF38_4153 ENOG4105ECK Fatty Acid Desaturase BF38_4154 ENOG4105G6Z alkaline phosphatase BF38_4156 ENOG4105VMP Transcriptional regulator BF38_4159 ENOG41090T1 Membrane BF38_416 ENOG4105C28 cystathionine BF38_4161 ENOG4108WCX response regulator BF38_4163 ENOG41068WN BF38_4169 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF38_4174 ENOG4105CKK Glycosyl transferase, family 2 BF38_4178 ENOG4105CKK Glycosyl transferase, family 2 BF38_4180 ENOG4105C8Y Acetylornithine aminotransferase BF38_4188 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BF38_4190 ENOG4108TVJ Nitroreductase BF38_4191 ENOG4105FS7 Transcriptional regulator BF38_4195 ENOG4105ERH Fumarylacetoacetate hydrolase BF38_4199 ENOG4105CEY Amp-dependent synthetase and ligase BF38_420 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BF38_4200 ENOG4105CHU acetyl-coa acetyltransferase BF38_4201 ENOG4105E39 Enoyl-CoA hydratase BF38_4202 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BF38_4203 ENOG4105CS2 ec 3.2.1.21 BF38_4204 ENOG4105VCP PTS System BF38_4205 ENOG4108QVC Component IIC BF38_4206 ENOG4107XMU Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BF38_4208 ENOG4105VZJ PTS System BF38_4210 ENOG4105G9B Transcriptional regulator BF38_4211 ENOG4105D2S major facilitator superfamily BF38_4212 ENOG4105EFZ amidohydrolase BF38_4218 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF38_4219 ENOG4105CMR udp-glucose 4-epimerase BF38_422 ENOG4105EMN RNA polymerase sigma factor BF38_4220 ENOG4105C19 ABC transporter BF38_4226 ENOG4108XET gCN5-related N-acetyltransferase BF38_4239 ENOG410635A Membrane BF38_4240 ENOG4105KNA -acetyltransferase BF38_4241 ENOG4108IQI permease BF38_4243 ENOG4105F1N DNA alkylation repair BF38_4249 ENOG4107RF6 penicillin-binding protein BF38_425 ENOG4105F1V Acetoin utilization protein BF38_4257 ENOG4105P4J Allophanate hydrolase, subunit 1 BF38_4258 ENOG4107258 Transcriptional regulator BF38_426 ENOG4105W87 Cbs domain BF38_4260 ENOG4106N3A copper homeostasis protein cutc BF38_4261 ENOG4108ZRV stage ii sporulation protein p BF38_4262 ENOG4108ZHR arsR family transcriptional regulator BF38_4264 ENOG4105FDT acyl-CoA dehydrogenase BF38_4268 ENOG4105DWD nucleoside recognition domain protein BF38_427 ENOG4105DGU Histone deacetylase BF38_4274 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BF38_428 ENOG4106HB6 Alpha beta hydrolase BF38_4289 ENOG4105E2A Dehydrogenase BF38_4291 ENOG4108IJ0 Aspartate ammonia-lyase BF38_4292 ENOG4105HDK L-asparaginase BF38_4293 ENOG4108IMY Transcriptional regulator BF38_4296 ENOG4108B31 Spore germination protein BF38_4298 ENOG4105BZU Histidine kinase BF38_430 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF38_4303 ENOG41075H3 AraC family transcriptional regulator BF38_4304 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BF38_4305 ENOG4105CUB amino acid BF38_4307 ENOG4105II7 pyrroline-5-carboxylate reductase BF38_4310 ENOG4108NHD germination protein BF38_4311 ENOG4108Q8B Spore germination protein BF38_4315 ENOG4105CSV Glutaminase BF38_4318 ENOG4105CGH 5'-nucleotidase BF38_4319 ENOG4105CH6 catalase BF38_432 ENOG4107SNB ankyrin repeat protein YahD BF38_4321 ENOG4105CHJ isochorismatase hydrolase BF38_4322 ENOG4105CHJ isochorismatase hydrolase BF38_4326 ENOG41090MY MarR family Transcriptional regulator BF38_433 ENOG4105EP9 oxidoreductase BF38_4333 ENOG4108606 TspO/MBR family BF38_4334 ENOG4105CVP deoxyribo-dipyrimidine photolyase BF38_4337 ENOG4108TWJ NADH dehydrogenase subunit 5 BF38_4338 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BF38_4340 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BF38_4341 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) BF38_4348 ENOG4105D6J arsenicaL-resistance protein BF38_4349 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BF38_4350 ENOG41085FC arsR family transcriptional regulator BF38_4354 ENOG4105BZU Histidine kinase BF38_4355 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_4357 ENOG4107P5I polyketide synthase BF38_4358 ENOG4108IG5 Transcriptional regulator BF38_4359 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BF38_4360 ENOG4108YXU transcriptional regulator AsnC family BF38_4372 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BF38_4373 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF38_4375 ENOG4105IIP Membrane BF38_4378 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_4379 ENOG41062D9 Histidine kinase BF38_4384 ENOG4105K6H D-cysteine desulfhydrase BF38_4389 ENOG4108NNI Beta-lactamase domain-containing protein BF38_439 ENOG4105ETE Transcriptional regulator (LacI family BF38_4390 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BF38_4392 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BF38_4395 ENOG4105C88 aminopeptidase BF38_4397 ENOG4105W1Y Transcriptional regulator BF38_4402 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BF38_4403 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BF38_4406 ENOG4105BZU Histidine kinase BF38_4408 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BF38_4409 ENOG4105DJB Major Facilitator Superfamily BF38_4410 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) BF38_4411 ENOG4107QR9 Iron-sulfur cluster binding protein BF38_4413 ENOG4106P55 Transcriptional regulator BF38_4415 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BF38_4421 ENOG4105TRI Hydrolase BF38_4428 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BF38_443 ENOG4105C88 aminopeptidase BF38_4434 ENOG4105C44 Serine transporter BF38_4435 ENOG4105EJQ L-serine dehydratase BF38_4437 ENOG4108JPW Aminotransferase BF38_4439 ENOG4105C45 hydrogenase expression formation protein (HypE) BF38_4440 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) BF38_4442 ENOG4105DVH amino acid BF38_4445 ENOG4108JQ1 Dehydrogenase BF38_4449 ENOG41082W1 Cupin 2, conserved barrel domain protein BF38_4450 ENOG410874W AraC family transcriptional regulator BF38_4454 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF38_4462 ENOG4108ISG Major Facilitator BF38_4464 ENOG4107MII Sugar-specific transcriptional regulator TrmB BF38_4465 ENOG4105CZM Major Facilitator BF38_4467 ENOG4105RXJ BF38_4468 ENOG4105KPY Small multidrug resistance protein BF38_4469 ENOG4105KBX Transcriptional regulator, TetR family BF38_4471 ENOG4105CRW Short chain fatty acid transporter BF38_4473 ENOG4105DYS nad(p)h dehydrogenase (quinone) BF38_448 ENOG4108IPJ Membrane BF38_4480 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BF38_4487 ENOG4105EQ0 Major Facilitator superfamily BF38_4488 ENOG4108IND Tetr family transcriptional regulator BF38_4490 ENOG41067QW Transcriptional regulator BF38_4491 ENOG4108Z66 YbaK ebsC protein BF38_4495 ENOG4105KVH Transcriptional regulator BF38_4496 ENOG4108RCM Nitroreductase BF38_4500 ENOG4108PSK reductase BF38_4502 ENOG4105CJ1 ABC, transporter BF38_4514 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BF38_4515 ENOG4105DKQ ROK family BF38_4516 ENOG4106UW1 Major Facilitator superfamily BF38_4517 ENOG4108UW5 maltose o-acetyltransferase BF38_4519 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BF38_4521 ENOG4105C31 Tryptophanyl-tRNA synthetase BF38_4527 ENOG4105DMQ Methyltransferase BF38_4529 ENOG4105EV4 Multidrug resistance protein mdtH BF38_4535 ENOG4105C37 (CBS) domain BF38_4538 ENOG4105DDN Pentapeptide repeat-containing protein BF38_4539 ENOG4105XDF Protein of unknown function (DUF1272) BF38_454 ENOG4108VDD TRNA binding domain protein BF38_4540 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BF38_4541 ENOG4105CMG Carbohydrate kinase BF38_4542 ENOG4105C6Z Gluconate BF38_4543 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BF38_4546 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BF38_4548 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone BF38_4551 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BF38_4552 ENOG4105D4Y metalloprotease BF38_4559 ENOG4105C44 Serine transporter BF38_4565 ENOG4105KVH Transcriptional regulator BF38_4566 ENOG4108TZY GntR Family Transcriptional Regulator BF38_4567 ENOG4105D9R oxidoreductase BF38_4568 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BF38_4569 ENOG4105KVH Transcriptional regulator BF38_4570 ENOG4105KVH Transcriptional regulator BF38_4578 ENOG4105JAB phenazine biosynthesis protein, phzf family BF38_4581 ENOG4105CHR reductase BF38_4585 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BF38_4586 ENOG4105KVH Transcriptional regulator BF38_4588 ENOG4108ZJ4 polysaccharide deacetylase BF38_4597 ENOG4105KAF membrAne BF38_46 ENOG4105EGD dinuclear metal center protein, YbgI family BF38_460 ENOG4105C8F Beta-lactamase domain protein BF38_4602 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BF38_4613 ENOG4105H3G oxidoreductase BF38_4620 ENOG4105CIS alcohol dehydrogenase BF38_4627 ENOG4108TN2 lmbE family BF38_4629 ENOG4107R3E Citrate transporter BF38_463 ENOG4108V15 phosphotransferase enzyme family BF38_4632 ENOG4108MES Periplasmic binding protein BF38_4633 ENOG4105EHG Permease protein BF38_4634 ENOG4105DQ5 transport system permease protein BF38_4635 ENOG4105NX3 Membrane BF38_4636 ENOG4107ZY0 Phenazine biosynthesis-like protein BF38_464 ENOG4108IUM Glycogen debranching enzyme BF38_4640 ENOG4107CUJ Protein of unknown function (DUF2690) BF38_4642 ENOG4107V2S Transcriptional regulator BF38_4646 ENOG4105C98 muts2 protein BF38_4648 ENOG4105E5K Alpha-amylase BF38_4649 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BF38_4650 ENOG4105DPN Oligoendopeptidase f BF38_4651 ENOG4108A04 Beta-lactamase BF38_4657 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BF38_466 ENOG4107QSE Dipeptidase BF38_4661 ENOG41082BM Transcriptional regulator, arsr family BF38_4662 ENOG4105CIS alcohol dehydrogenase BF38_467 ENOG4105YW5 deoR family transcriptional regulator BF38_4672 ENOG4105RHY Pfam:UPF0157 BF38_4674 ENOG4105C09 Bile acid BF38_4675 ENOG4105CQB FAD linked oxidase domain protein BF38_4679 ENOG4108UT6 Transferase hexapeptide repeat containing protein BF38_4681 ENOG4105K64 Glycosyl transferase, family 2 BF38_4682 ENOG4105E39 Enoyl-CoA hydratase BF38_4684 ENOG4105KT7 mgtC SapB transporter BF38_4686 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BF38_4687 ENOG41073R8 VanW family BF38_4689 ENOG4108R1P BF38_4693 ENOG4105VEQ Cold shock protein BF38_4697 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BF38_470 ENOG4105CBX hi0933 family BF38_4702 ENOG4105DQ6 Transposase BF38_4706 ENOG4105DR5 peptidase BF38_4707 ENOG41065S2 pneumococcal vaccine antigen BF38_4708 ENOG4107YXZ hydrolase, family 25 BF38_4709 ENOG4105DR5 peptidase BF38_4721 ENOG410904N short-chain dehydrogenase reductase BF38_4723 ENOG4106IQC argininosuccinate lyase BF38_4726 ENOG4108IA2 Sodium pantothenate symporter BF38_4728 ENOG4105C26 Dehydrogenase BF38_4729 ENOG4105CHR reductase BF38_4731 ENOG4105EWU Squalene--hopene cyclase BF38_4733 ENOG4105FR1 rard protein BF38_4734 ENOG410696E Membrane BF38_4737 ENOG4105D1F ATP-binding protein BF38_4739 ENOG4108ZAF Molybdopterin BF38_4740 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF38_4741 ENOG4105D06 uba thif-type nad fad binding protein BF38_4742 ENOG4105TMB Formate nitrite transporter BF38_4744 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BF38_4745 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BF38_4747 ENOG4108JB9 formate dehydrogenase BF38_4749 ENOG4105E1K spore germination protein BF38_4761 ENOG4105DQ6 Transposase BF38_4764 ENOG4107QJT sodium dicarboxylate symporter BF38_4765 ENOG4108KGH TRANSCRIPTIONal BF38_4767 ENOG4105EMN RNA polymerase sigma factor BF38_477 ENOG4108VJ1 Transcriptional regulator (CarD family BF38_4771 ENOG4105CIG ABC transporter BF38_4773 ENOG4105D9R oxidoreductase BF38_4775 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF38_4776 ENOG4105K4P CoA-binding domain protein BF38_4777 ENOG4105C0H protease BF38_4778 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_478 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BF38_4780 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BF38_4781 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BF38_4782 ENOG4105W8X HesB YadR YfhF-family protein BF38_4788 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BF38_4789 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BF38_4791 ENOG4108JJA ABC, transporter BF38_4792 ENOG4108I0Z Aconitate hydratase BF38_4798 ENOG4105E5W Transporter BF38_4800 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BF38_4804 ENOG4107F3J Amp-dependent synthetase and ligase BF38_4805 ENOG4107ZYJ bioY protein BF38_4806 ENOG4105CEY Amp-dependent synthetase and ligase BF38_4815 ENOG4107AYK membrAne BF38_4817 ENOG4105BZU Histidine kinase BF38_4818 ENOG4105FBA Phospholipase Carboxylesterase BF38_4819 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BF38_482 ENOG4108ZAF Molybdopterin BF38_4820 ENOG4105CK7 Sodium proline symporter BF38_4821 ENOG4105CBC glutamate synthase BF38_4822 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BF38_4823 ENOG4108VJ1 Transcriptional regulator (CarD family BF38_4824 ENOG4108903 Formimidoylglutamase BF38_483 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BF38_4830 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BF38_4837 ENOG4107QIV Cytochrome c biogenesis protein BF38_4839 ENOG4105CH2 amidohydrolase BF38_484 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF38_4841 ENOG4105CJ1 ABC, transporter BF38_4843 ENOG4107RSM transcriptional regulator BF38_4845 ENOG41067MG lrgb family BF38_4850 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF38_4853 ENOG4105BZ1 (ABC) transporter BF38_4854 ENOG4105BZ1 (ABC) transporter BF38_4858 ENOG4105D7V transposase BF38_486 ENOG4105D06 uba thif-type nad fad binding protein BF38_4861 ENOG4105D5T phosphonate abc transporter BF38_4862 ENOG4108HW3 (ABC) transporter BF38_4863 ENOG4105CGH 5'-nucleotidase BF38_4865 ENOG4108SVB resolvase BF38_4869 ENOG4105K7K Transcriptional regulator BF38_487 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BF38_4875 ENOG4105C5F glutamine synthetase BF38_4876 ENOG4105KV4 Transcriptional regulator BF38_4877 ENOG4105CXI aluminum resistance protein BF38_4878 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF38_4879 ENOG4105EN6 Membrane BF38_4881 ENOG4106F1P AAA ATPase, central domain protein BF38_4887 ENOG41069ER domain protein BF38_4888 ENOG4105DM4 PTS System BF38_4889 ENOG4105DE4 1-phosphofructokinase BF38_4890 ENOG4105E98 transcriptional regulator DeoR family BF38_4891 ENOG4107QW4 alcohol dehydrogenase BF38_4892 ENOG4108SJC Membrane BF38_4895 ENOG4105C85 amino acid BF38_4899 ENOG4105TMB Formate nitrite transporter BF38_49 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_4900 ENOG4105K70 DNA-binding protein BF38_4901 ENOG4105C59 p-type ATPase BF38_4902 ENOG410681U heavy metal transport detoxification protein BF38_4903 ENOG4105VPX protein, conserved in bacteria BF38_4905 ENOG4105NIV Esterase BF38_4906 ENOG4105E0A ABC, transporter BF38_491 ENOG41085GJ domain protein BF38_4910 ENOG4105CGK Exodeoxyribonuclease III BF38_4912 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BF38_4913 ENOG4105D03 DNA-3-methyladenine glycosylase II BF38_4919 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BF38_4920 ENOG4105BZU Histidine kinase BF38_4923 ENOG41067MG lrgb family BF38_4928 ENOG4107YEI lmbE family BF38_493 ENOG4105DWV Homoserine O-trans-acetylase BF38_4932 ENOG4105F0V Cell wall hydrolase BF38_4933 ENOG4107R6R udp-galactopyranose mutase BF38_4934 ENOG4105E0M Sulfatase BF38_4935 ENOG410890F Dynamin family BF38_4937 ENOG4107QHE Choloylglycine hydrolase BF38_4943 ENOG4105DQU oxidoreductase, subunit beta BF38_4944 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BF38_4945 ENOG4108IGT Dipeptidase BF38_4946 ENOG4105MCT stage V sporulation protein S BF38_4947 ENOG4105D48 metallophosphoesterase BF38_495 ENOG4108B31 Spore germination protein BF38_4952 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BF38_4955 ENOG4105XZV Protein of unknown function (DUF3243) BF38_4956 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BF38_4960 ENOG4105UIB (ABC) transporter BF38_4961 ENOG4108JQ9 ABC transporter BF38_4962 ENOG4105DIH basic membrane BF38_4963 ENOG4105FDP GntR family transcriptional regulator BF38_4964 ENOG4107QZI cell division protein FtsK BF38_4966 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BF38_4968 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BF38_4970 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF38_4971 ENOG4108S0H Dipicolinic acid synthetase, b subunit BF38_4972 ENOG4105E35 Dipicolinate synthase subunit A BF38_4974 ENOG4105C1V Peptidase, M16 BF38_4978 ENOG4105DTN riboflavin biosynthesis protein ribF BF38_4979 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BF38_4981 ENOG4105W7A Protein of unknown function (DUF503) BF38_4983 ENOG4105VHM ribosomal protein BF38_4984 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BF38_4985 ENOG4105CHV Transcription elongation factor NusA BF38_4987 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BF38_4989 ENOG4105DZP Membrane-associated zinc metalloprotease BF38_4990 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BF38_4991 ENOG4105KNE Phosphatidate cytidylyltransferase BF38_50 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BF38_5000 ENOG4108HE4 integrase family BF38_5002 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BF38_5003 ENOG4105C79 DNA protecting protein DprA BF38_5004 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BF38_5007 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BF38_501 ENOG410605W Major Facilitator BF38_5012 ENOG4105VB6 UPF0109 protein BF38_5016 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BF38_5017 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BF38_502 ENOG4107S91 Sodium hydrogen exchanger BF38_5020 ENOG4105CHR reductase BF38_5021 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BF38_5024 ENOG4105CB5 ATP-dependent DNA helicase recG BF38_5025 ENOG4105DP4 dak2 domain fusion protein ylov BF38_5026 ENOG4108ZAA Alkaline-shock protein BF38_5028 ENOG4105FJ0 thiamine BF38_5029 ENOG4105DJV ribulose-phosphate 3-epimerase BF38_503 ENOG4105NCW Trka-c domain protein BF38_5030 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BF38_5031 ENOG4105D9P serine threonine protein kinase BF38_5032 ENOG4108ZF3 Phosphatase BF38_5034 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BF38_5036 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BF38_5037 ENOG4105C25 Primosomal protein n' BF38_5038 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BF38_5042 ENOG4105DSJ YicC domain protein BF38_5044 ENOG4105F23 Fibronectin-binding protein BF38_5045 ENOG4105DC7 peptidase M24 BF38_5057 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BF38_506 ENOG4105C19 ABC transporter BF38_5062 ENOG4105C34 Pseudouridine synthase BF38_5067 ENOG4105DBK s4 domain protein BF38_5068 ENOG41067XK integral membrane protein BF38_5070 ENOG4105DFA alanine racemase domain protein BF38_5071 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BF38_5072 ENOG4105WR5 sporulation protein, YlmC YmxH family BF38_5074 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_5076 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BF38_5077 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BF38_5078 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BF38_5079 ENOG4105D4A Cell wall formation (By similarity) BF38_5080 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BF38_5081 ENOG4105CNI cell division protein FtsW BF38_5084 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF38_5085 ENOG4105CJN penicillin-binding protein BF38_5086 ENOG4105CJN penicillin-binding protein BF38_5087 ENOG41068DC Essential cell division protein (By similarity) BF38_5094 ENOG4105KNH Nucleic acid-binding protein BF38_5096 ENOG41063PX domain protein BF38_5097 ENOG4105D78 K07001 NTE family protein BF38_5099 ENOG4105H20 Sporulation integral membrane protein YlbJ BF38_510 ENOG4105N5T Radical SAM Protein BF38_5100 ENOG4106H78 methyltransferase BF38_5104 ENOG4107TB6 phosphoglycerate mutase BF38_5107 ENOG4106UY4 Inherit from COG: Scp-like extracellular BF38_5117 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BF38_5118 ENOG4105CNI cell division protein FtsW BF38_512 ENOG4105DA5 (ABC) transporter BF38_5121 ENOG4108IAB Phoh family BF38_5125 ENOG4105QA2 BF38_5126 ENOG4105CI3 gtp-binding protein typa BF38_5128 ENOG4105ECY inositol monophosphatase BF38_5132 ENOG4105CXN decarboxylase BF38_5142 ENOG4105CPP Dehydrogenase, E1 component BF38_5145 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BF38_5146 ENOG4108X4Q Hydrolase BF38_5148 ENOG4105CN5 Metallo-Beta-Lactamase BF38_5149 ENOG4107ZYR domain protein BF38_5156 ENOG4108XRC Protein of unknown function (DUF458) BF38_5158 ENOG4107IN1 Protein of unknown function (DUF1797) BF38_5161 ENOG4105EPM Diguanylate phosphodiesterase BF38_5162 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BF38_5165 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BF38_5167 ENOG4105UIN BF38_5178 ENOG4108HGU Histidine kinase BF38_518 ENOG4105E8V Alpha Beta Hydrolase Fold protein BF38_5180 ENOG4105CHM Aminotransferase BF38_5181 ENOG4105FKQ transcriptional regulator BF38_5182 ENOG4105EG2 ABC transporter, permease BF38_5184 ENOG4107FKK extracellular solute-binding protein family 1 BF38_5186 ENOG4105CG3 alpha amylase, catalytic region BF38_519 ENOG4108Z0R Transferase BF38_5195 ENOG4105CHU acetyl-coa acetyltransferase BF38_520 ENOG4105YVM Phosphoesterase, PA-phosphatase related BF38_5203 ENOG4105DTD Dehydrogenase BF38_5207 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BF38_521 ENOG4105BZF Glycosyl transferase (Group 1 BF38_5215 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BF38_5216 ENOG4106TD9 Diguanylate cyclase BF38_5220 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BF38_5223 ENOG4105CID antiterminator BF38_5225 ENOG4105FDP GntR family transcriptional regulator BF38_5227 ENOG4105CE4 GlcNAc 6-P deacetylase BF38_523 ENOG4108RIR Molybdenum cofactor biosynthesis protein BF38_5234 ENOG4107ZE5 PPIases accelerate the folding of proteins BF38_5235 ENOG4105PTM secreted protein BF38_5236 ENOG4105J7I hydrolase BF38_5238 ENOG4105G6R Stage v sporulation protein ae BF38_5240 ENOG4105CZ3 stage V sporulation protein ad BF38_5241 ENOG41090VF Stage v sporulation protein ac BF38_5245 ENOG4105C8J )-transporter BF38_5246 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_5248 ENOG41082AN stage II sporulation protein BF38_5249 ENOG4105DZ1 carboxypeptidase BF38_5250 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF38_5251 ENOG4105DVE abc transporter atp-binding protein BF38_5258 ENOG4105D7N magnesium and cobalt transport protein CorA BF38_5263 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF38_5265 ENOG4105I3K Ferric uptake regulator, Fur family BF38_5266 ENOG4105MZ9 stage II sporulation protein m BF38_5270 ENOG4105CPC Aldo Keto reductase BF38_5272 ENOG4105RHY Pfam:UPF0157 BF38_5276 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BF38_5278 ENOG4105ETE Transcriptional regulator (LacI family BF38_5279 ENOG4108YM7 Gcn5-related n-acetyltransferase BF38_5283 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BF38_5284 ENOG4108R6K riboflavin synthase, subunit alpha BF38_5288 ENOG4107VUU Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BF38_5289 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF38_5290 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF38_5291 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BF38_5293 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BF38_5295 ENOG4105DFD Na H antiporter BF38_5296 ENOG4105CGH 5'-nucleotidase BF38_5304 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) BF38_5307 ENOG4108IXY short-chain dehydrogenase reductase BF38_5308 ENOG41069FQ Metallo-beta-lactamase superfamily BF38_5309 ENOG4105II7 pyrroline-5-carboxylate reductase BF38_5310 ENOG4105EJQ L-serine dehydratase BF38_5314 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BF38_5316 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BF38_5317 ENOG4105D9U N-acetyltransferase BF38_5319 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BF38_5320 ENOG4108QEG Membrane BF38_5321 ENOG4105CDA abc transporter atp-binding protein BF38_5322 ENOG4105E5Q amino acid AbC transporter BF38_5323 ENOG4108HW3 (ABC) transporter BF38_5325 ENOG4105G7B Protein of unknown function (DUF2992) BF38_5326 ENOG4105E09 nadh pyrophosphatase BF38_5328 ENOG4105C7S Dehydrogenase BF38_5329 ENOG4105CPP Dehydrogenase, E1 component BF38_5333 ENOG4107RDP Dehydrogenase BF38_5335 ENOG4108JUB Transcriptional regulator BF38_5337 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BF38_534 ENOG4105EGD dinuclear metal center protein, YbgI family BF38_5340 ENOG4107QQR Sporulation BF38_5341 ENOG4105S1Z Stage IV sporulation protein B BF38_5342 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BF38_5344 ENOG4105DX0 Hemolysin A BF38_5346 ENOG4105CTB Polyprenyl synthetase BF38_535 ENOG4105BZU Histidine kinase BF38_5351 ENOG4108ZSR alkaline shock protein BF38_5352 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BF38_5357 ENOG410644B Stage III sporulation protein af BF38_5359 ENOG4105KQ4 Stage iii sporulation protein ad BF38_536 ENOG4105BZU Histidine kinase BF38_5360 ENOG4108CQH stage III sporulation protein AC BF38_5361 ENOG4105KR5 Stage iii sporulation protein BF38_5362 ENOG4105CD2 stage iii sporulation protein aa BF38_5367 ENOG4105DC7 peptidase M24 BF38_537 ENOG4107S9D Alpha beta hydrolase BF38_5370 ENOG4105CBJ Metal-dependent enzyme BF38_5371 ENOG4107YBY Hydrolase BF38_5376 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BF38_5377 ENOG4105WZW rhodanese family BF38_538 ENOG4107T7U Sulfatase BF38_5381 ENOG41080TC multidrug resistance protein BF38_5388 ENOG4105CJ1 ABC, transporter BF38_5389 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BF38_5395 ENOG4105C0D helicase BF38_541 ENOG4105D2X ABC transporter substrate-binding protein BF38_5415 ENOG4105K4H Nlp p60 protein BF38_5421 ENOG4105EWI Short-chain dehydrogenase reductase Sdr BF38_543 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BF38_5446 ENOG4105M6F mutator MutT protein BF38_5447 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 BF38_5449 ENOG4105W5Q DNA repair protein (RadC BF38_546 ENOG4107XGZ Hydrolase BF38_5468 ENOG4105E1K spore germination protein BF38_5470 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BF38_5480 ENOG4105D7V transposase BF38_5481 ENOG4108IMY Transcriptional regulator BF38_5482 ENOG4105HDK L-asparaginase BF38_5483 ENOG4105DUX Transporter BF38_5484 ENOG4105DQ6 Transposase BF38_5492 ENOG4107TVC Glycosyl transferase, family 2 BF38_5495 ENOG4107R51 Glycosyl transferase, family 2 BF38_5498 ENOG4105CJ1 ABC, transporter BF38_55 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BF38_5500 ENOG4105K7K Transcriptional regulator BF38_5510 ENOG4106WTF Glycosyl transferase, family 2 BF38_553 ENOG4108V2W Carbonate dehydratase BF38_5539 ENOG41068WN BF38_555 ENOG4105C4M (Ubiquinol oxidase) subunit I BF38_5555 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BF38_5559 ENOG4105CJW magnesium transporter BF38_556 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF38_5569 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BF38_5570 ENOG4105YWU small acid-soluble spore protein BF38_5583 ENOG4105W8Z 4'-phosphopantetheinyl transferase BF38_5588 ENOG4105DUM transcriptional regulator, lysR family BF38_5589 ENOG4105DWP Membrane BF38_5591 ENOG4106J6E BF38_5597 ENOG4105CEY Amp-dependent synthetase and ligase BF38_5598 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BF38_5599 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BF38_56 ENOG4105KG3 cytidine deaminase BF38_5601 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BF38_5602 ENOG4105W8Z 4'-phosphopantetheinyl transferase BF38_5604 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BF38_5607 ENOG4105C0W non-ribosomal peptide synthetase BF38_5607 ENOG4105C0W non-ribosomal peptide synthetase BF38_5610 ENOG4107SQU synthase BF38_5611 ENOG4107SQU synthase BF38_5612 ENOG4105CPQ Dehydrogenase BF38_5613 ENOG4108JPW Aminotransferase BF38_5615 ENOG4107QKG PfaD family BF38_5616 ENOG4108151 Beta-lactamase domain protein BF38_5617 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BF38_5633 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_5643 ENOG4105D7V transposase BF38_565 ENOG41087YS Phage shock protein A BF38_5660 ENOG4105EQI Metal Dependent Phosphohydrolase BF38_5677 ENOG410906U SprT-like BF38_5682 ENOG4105C2M dna polymerase I BF38_57 ENOG4107YR5 Diacylglycerol kinase BF38_5707 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF38_5708 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BF38_5718 ENOG4105MZU cell filamentation protein BF38_572 ENOG4105BZU Histidine kinase BF38_573 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_5734 ENOG4105IEH endo-beta-N-acetylglucosaminidase BF38_5766 ENOG4108VXD carboxy-peptidase BF38_578 ENOG4108UGV hypoxanthine phosphoribosyltransferase BF38_579 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BF38_5810 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BF38_5824 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF38_5825 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF38_584 ENOG4107ZTW SNARE associated Golgi BF38_587 ENOG4105C19 ABC transporter BF38_5879 ENOG4107XK4 dna polymerase iii subunits gamma and tau BF38_588 ENOG41086D8 Transcriptional regulator BF38_59 ENOG4105CTJ Metal Dependent Phosphohydrolase BF38_5939 ENOG4105C2M dna polymerase I BF38_596 ENOG4105C6Z Gluconate BF38_597 ENOG4105FDP GntR family transcriptional regulator BF38_5996 ENOG4105C4R Atp-dependent dna helicase BF38_60 ENOG4105C9A Phoh family BF38_601 ENOG41069H0 dihydroorotase EC 3.5.2.3 BF38_6018 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BF38_607 ENOG4105DTQ mandelate racemase muconate lactonizing BF38_609 ENOG4108IPT Naphthoate synthase BF38_610 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BF38_6102 ENOG4105D9P serine threonine protein kinase BF38_6105 ENOG4106CGH Phage Mu protein F like protein BF38_6106 ENOG4108MDF Phage Portal Protein BF38_611 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BF38_6115 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) BF38_612 ENOG4105E4F Isochorismate synthase BF38_6120 ENOG4107ZFB This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) BF38_6128 ENOG4106CVF DNA replication protein BF38_613 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BF38_6140 ENOG4108IMY Transcriptional regulator BF38_615 ENOG4105VEQ Cold shock protein BF38_6161 ENOG4108M15 ABC transporter BF38_6162 ENOG4105KCT ABC transporter BF38_6170 ENOG4105DUX Transporter BF38_6173 ENOG41060AI SEC-C motif BF38_6177 ENOG4107QJE Chromosome Partitioning Protein BF38_6181 ENOG41061CK Antibiotic biosynthesis monooxygenase BF38_6186 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BF38_6191 ENOG4105XSJ toxin secretion phage lysis holin BF38_62 ENOG41068P3 sporulation protein YqfC BF38_6202 ENOG41060SN BF38_6207 ENOG4107QJE Chromosome Partitioning Protein BF38_6214 ENOG4108J59 Extracellular solute-binding protein, family 5 BF38_6217 ENOG4105DVF Cytosine-specific methyltransferase BF38_622 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BF38_6223 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BF38_6228 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF38_6237 ENOG4105C9U ATP-dependent DNA helicase RecQ BF38_625 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF38_6253 ENOG4105K4H Nlp p60 protein BF38_627 ENOG4105JVQ RNA Polymerase BF38_63 ENOG4105KTH gatB Yqey BF38_646 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BF38_65 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BF38_654 ENOG4105KT7 mgtC SapB transporter BF38_656 ENOG4107PBV potassium channel BF38_658 ENOG4105WG9 Conserved Protein BF38_66 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BF38_660 ENOG4105CHM Aminotransferase BF38_661 ENOG4108ZB6 transcriptional regulator AsnC family BF38_662 ENOG4105C5I Dehydrogenase BF38_663 ENOG4108MUZ hydrolase BF38_665 ENOG4105C87 Aminotransferase class I and II BF38_668 ENOG4105Y38 Kinase-associated protein B BF38_670 ENOG4107R3E Citrate transporter BF38_673 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BF38_674 ENOG4105KA0 thioesterase Superfamily protein BF38_678 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BF38_682 ENOG41069ER domain protein BF38_685 ENOG4105CEP NADH dehydrogenase BF38_691 ENOG4105EWC Purine nucleoside phosphorylase BF38_695 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BF38_70 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BF38_701 ENOG4105C4B ABC transporter, permease BF38_702 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BF38_707 ENOG41083MR nifu domain-containing protein BF38_710 ENOG4108W5N phosphatidylglycerophosphatase a BF38_712 ENOG4105DYS nad(p)h dehydrogenase (quinone) BF38_714 ENOG4105D4U had-superfamily hydrolase, subfamily iia BF38_717 ENOG4105CBT Fructose-1,6-bisphosphatase BF38_72 ENOG4105CSA Coproporphyrinogen iii oxidase BF38_720 ENOG4105MMD transcriptional regulator BF38_721 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BF38_722 ENOG4107TXC Transcriptional regulator BF38_723 ENOG41090T1 Membrane BF38_728 ENOG4105FAA peptidase M23 BF38_73 ENOG4105KVH Transcriptional regulator BF38_730 ENOG4105KZD Domain of unknown function (DUF1805) BF38_731 ENOG4107R8B 5'-nucleotidase BF38_732 ENOG4105DIW FeS assembly protein SUFB BF38_733 ENOG4108UNV SUF system FeS assembly protein, NifU family BF38_734 ENOG4105C9B Cysteine desulfurase BF38_735 ENOG4105JRK feS assembly protein SufD BF38_736 ENOG4105C3K feS assembly ATPase SufC BF38_737 ENOG4105D01 (LipO)protein BF38_738 ENOG4105D01 (LipO)protein BF38_739 ENOG4108UMI ABC transporter, permease BF38_745 ENOG41080E8 Transcriptional regulator, Spx MgsR family BF38_756 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BF38_764 ENOG4108W8B Beta-lactamase domain protein BF38_765 ENOG4105C1G acyl-Coa dehydrogenase BF38_766 ENOG4105CHU acetyl-coa acetyltransferase BF38_769 ENOG4105DZ1 carboxypeptidase BF38_773 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF38_777 ENOG4108SUT Major Facilitator Superfamily BF38_778 ENOG4107R7I amino acid BF38_78 ENOG4105TQK DNA polymerase iii, delta' subunit BF38_780 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BF38_782 ENOG4107AYK membrAne BF38_79 ENOG4105TQK DNA polymerase iii, delta' subunit BF38_790 ENOG4107ZTW SNARE associated Golgi BF38_792 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BF38_793 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_794 ENOG4105BZU Histidine kinase BF38_798 ENOG4105C8Q Methyl-accepting chemotaxis BF38_799 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BF38_800 ENOG4105VG1 fes assembly suf system protein BF38_801 ENOG4105D4Y metalloprotease BF38_805 ENOG4107S91 Sodium hydrogen exchanger BF38_806 ENOG4105NCW Trka-c domain protein BF38_808 ENOG4108RMU ferritin dps family protein BF38_81 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BF38_811 ENOG4108URH decarboxylase BF38_815 ENOG4105D9N nucleoside BF38_816 ENOG4105D9N nucleoside BF38_818 ENOG4108RYK Nad-dependent epimerase dehydratase BF38_82 ENOG4108UK2 deaminase BF38_822 ENOG4105CV8 reductase BF38_823 ENOG4105F27 Major Facilitator BF38_824 ENOG4105KVH Transcriptional regulator BF38_827 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BF38_828 ENOG4105D4A Cell wall formation (By similarity) BF38_83 ENOG4105KQC Competence protein BF38_832 ENOG4105C8Q Methyl-accepting chemotaxis BF38_838 ENOG4108MK9 spermidine N(1)-acetyltransferase BF38_839 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BF38_842 ENOG4108IPW abc transporter atp-binding protein BF38_843 ENOG4105CM4 permease protein BF38_85 ENOG4105DXX methyltransferase BF38_857 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BF38_859 ENOG4105XZU Preprotein translocase, subunit SecG BF38_860 ENOG41067MG lrgb family BF38_864 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BF38_87 ENOG4108WF2 Metal Dependent Phosphohydrolase BF38_870 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_874 ENOG41090VF Stage v sporulation protein ac BF38_875 ENOG4105CZ3 stage V sporulation protein ad BF38_878 ENOG4105H67 Protein of unknown function (DUF421) BF38_879 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BF38_880 ENOG4105KRI phosphocarrier protein (HPr BF38_882 ENOG4105CHW UPF0052 protein BF38_884 ENOG4108Z4K mutator MutT protein BF38_886 ENOG4105C3M thioredoxin reductase BF38_888 ENOG4108S4C acetyltransferase BF38_89 ENOG410812S Rna-binding protein BF38_892 ENOG41086DT Membrane protein of unknown function BF38_894 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BF38_895 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BF38_898 ENOG4107TXC Transcriptional regulator BF38_903 ENOG4105HMI Membrane BF38_904 ENOG4105DUM transcriptional regulator, lysR family BF38_906 ENOG4108WS4 fmn reductase BF38_909 ENOG4105BZ1 (ABC) transporter BF38_91 ENOG4105CQW ribosome biogenesis GTPase YqeH BF38_911 ENOG4105CN1 protease BF38_912 ENOG4105CRP Part of the ABC transporter FtsEX involved in BF38_913 ENOG4105CAK Cell division ATP-binding protein ftsE BF38_915 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BF38_917 ENOG4105MS2 ribosomal subunit Interface protein BF38_918 ENOG4105VEQ Cold shock protein BF38_919 ENOG41081UC Inherit from COG: Competence protein BF38_92 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BF38_922 ENOG4105KVH Transcriptional regulator BF38_924 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BF38_925 ENOG4108KGH TRANSCRIPTIONal BF38_926 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BF38_927 ENOG4105C6Y Udp-glucose 6-dehydrogenase BF38_928 ENOG4105ESV Glycosyl transferase, family 4 BF38_930 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BF38_934 ENOG4105F8D glycoside hydrolase family 4 BF38_935 ENOG4105VCP PTS System BF38_936 ENOG4105CK1 PTS System BF38_938 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BF38_940 ENOG4105VCP PTS System BF38_942 ENOG4105VZJ PTS System BF38_945 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BF38_946 ENOG4105ECB domain protein BF38_947 ENOG4107RSM transcriptional regulator BF38_95 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_954 ENOG4105DAA L-lactate BF38_956 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BF38_958 ENOG4105E0M Sulfatase BF38_963 ENOG4107R8N Glycosyl transferase, family 2 BF38_965 ENOG4105C94 Transporter BF38_966 ENOG41069ER domain protein BF38_971 ENOG4105KBK Zinc finger, swim domain protein BF38_972 ENOG4105C0D helicase BF38_978 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF38_981 ENOG4107RBB ABC transporter, permease BF38_982 ENOG4105C19 ABC transporter BF38_986 ENOG4105CXY transporter BF38_989 ENOG4105BZU Histidine kinase BF38_99 ENOG4108TVJ Nitroreductase BF38_990 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF38_991 ENOG4105CMR udp-glucose 4-epimerase BF38_993 ENOG4108KGH TRANSCRIPTIONal BF38_994 ENOG4105CMR udp-glucose 4-epimerase BF38_995 ENOG4105C6Y Udp-glucose 6-dehydrogenase