locus-tag	class	description
BF38_1	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF38_100	COG2357	RelA SpoT domain protein
BF38_1001	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF38_1002	COG4464	protein tyrosine phosphatase activity
BF38_1003	COG0489	protein tyrosine kinase activity
BF38_1004	COG3944	biosynthesis protein
BF38_1005	COG0489	protein tyrosine kinase activity
BF38_1008	COG1609	Transcriptional regulator
BF38_1009	COG0739	heme binding
BF38_1012	COG3279	Response regulator of the LytR AlgR family
BF38_1013	COG2385	sporulation resulting in formation of a cellular spore
BF38_1014	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF38_1016	COG4836	Membrane
BF38_1017	COG1007	ATP synthesis coupled electron transport
BF38_1018	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF38_1019	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF38_102	COG1785	Belongs to the alkaline phosphatase family
BF38_1021	COG0839	Belongs to the complex I subunit 6 family
BF38_1024	COG0649	NAD binding
BF38_1028	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF38_1029	COG5001	Diguanylate cyclase
BF38_1029	COG3300	MHYT domain
BF38_1039	COG0356	it plays a direct role in the translocation of protons across the membrane
BF38_104	COG2267	carboxylic ester hydrolase activity
BF38_1045	COG0698	ribose 5-phosphate isomerase
BF38_1047	COG2190	(PTS) system
BF38_1048	COG2259	Doxx family
BF38_1049	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF38_1052	COG0009	L-threonylcarbamoyladenylate synthase
BF38_1055	COG2890	protein-(glutamine-N5) methyltransferase activity
BF38_1056	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF38_1059	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF38_1060	COG1494	fructose-1,6-bisphosphatase
BF38_1061	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF38_1064	COG4821	SIS domain
BF38_1068	COG1960	acyl-CoA dehydrogenase activity
BF38_1069	COG1960	acyl-CoA dehydrogenase activity
BF38_1070	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF38_1071	COG0183	Belongs to the thiolase family
BF38_1072	COG0247	lactate metabolic process
BF38_1072	COG2181	nitrate reductase activity
BF38_1073	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF38_1075	COG5001	Diguanylate cyclase
BF38_1075	COG3300	MHYT domain
BF38_1078	COG2197	response regulator
BF38_1079	COG1131	(ABC) transporter
BF38_1080	COG0024	Methionine aminopeptidase
BF38_1082	COG2234	aminopeptidase activity
BF38_1086	COG1595	DNA-templated transcription, initiation
BF38_1088	COG4506	Protein conserved in bacteria
BF38_1089	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF38_1092	COG0010	Belongs to the arginase family
BF38_1093	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF38_1094	COG2814	Major facilitator Superfamily
BF38_1095	COG0789	Transcriptional regulator
BF38_1096	COG0584	glycerophosphoryl diester phosphodiesterase
BF38_1097	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF38_1099	COG1994	Peptidase M50
BF38_11	COG1410	methionine synthase
BF38_11	COG0646	methionine synthase
BF38_1101	COG1078	dGTPase activity
BF38_1102	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_1103	COG1120	ATPase activity
BF38_1104	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_1105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_1109	COG0095	Lipoate-protein ligase
BF38_111	COG1404	Belongs to the peptidase S8 family
BF38_1110	COG0280	phosphate acetyltransferase
BF38_1113	COG3773	Cell wall hydrolase
BF38_1115	COG2363	Small membrane protein
BF38_1117	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF38_1118	COG2233	PERMEase
BF38_1119	COG0561	phosphatase activity
BF38_112	COG3186	Phenylalanine-4-hydroxylase
BF38_1120	COG2814	Major facilitator Superfamily
BF38_1122	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF38_1123	COG1131	(ABC) transporter
BF38_1124	COG2755	lipolytic protein G-D-S-L family
BF38_1125	COG1609	Transcriptional regulator
BF38_1127	COG0460	homoserine dehydrogenase
BF38_1131	COG1011	Hydrolase
BF38_1132	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF38_1134	COG2197	response regulator
BF38_1135	COG2203	Gaf domain
BF38_1135	COG4585	Histidine kinase
BF38_1136	COG0351	phosphomethylpyrimidine kinase
BF38_1137	COG3706	GGDEF domain
BF38_1138	COG2879	small protein
BF38_1139	COG1966	Carbon starvation protein
BF38_114	COG2514	catechol 2,3-dioxygenase activity
BF38_1140	COG3279	Response regulator of the LytR AlgR family
BF38_1141	COG0477	Major facilitator Superfamily
BF38_1146	COG0840	transmembrane signaling receptor activity
BF38_1148	COG1607	acyl-coa hydrolase
BF38_115	COG2259	Doxx family
BF38_1151	COG0488	(ABC) transporter
BF38_1155	COG0463	Glycosyl transferase, family 2
BF38_1156	COG1309	transcriptional regulator
BF38_1157	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF38_1158	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF38_1158	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF38_1159	COG0628	permease
BF38_1162	COG3279	Response regulator of the LytR AlgR family
BF38_1163	COG3275	phosphorelay sensor kinase activity
BF38_1164	COG2814	Major facilitator Superfamily
BF38_1165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF38_1166	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF38_1167	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF38_1171	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF38_1172	COG1272	protein, Hemolysin III
BF38_1177	COG1164	Oligoendopeptidase f
BF38_1181	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF38_1182	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF38_1183	COG4853	Protein conserved in bacteria
BF38_1184	COG4863	YycH protein
BF38_1185	COG5002	protein histidine kinase activity
BF38_1186	COG0745	RESPONSE REGULATOR receiver
BF38_1192	COG0305	Participates in initiation and elongation during chromosome replication
BF38_1194	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF38_1195	COG4241	membrane
BF38_1197	COG0629	single-stranded DNA binding
BF38_1199	COG0012	GTP binding
BF38_12	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF38_12	COG0646	methionine synthase
BF38_1200	COG4481	Protein conserved in bacteria
BF38_1201	COG0668	transmembrane transport
BF38_1203	COG1475	DNA binding
BF38_1204	COG1192	Involved in chromosome partitioning
BF38_1208	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF38_1209	COG1847	R3H domain protein
BF38_1210	COG0706	membrane insertase activity
BF38_1214	COG0592	DNA-directed DNA polymerase activity
BF38_1215	COG2501	S4 domain
BF38_1219	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF38_1225	COG0516	GMP reductase activity
BF38_1225	COG0517	IMP dehydrogenase activity
BF38_1226	COG1686	Belongs to the peptidase S11 family
BF38_123	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_1232	COG1428	Deoxynucleoside kinase
BF38_1233	COG1428	Deoxynucleoside kinase
BF38_1234	COG1335	isochorismatase
BF38_1235	COG0590	tRNA wobble adenosine to inosine editing
BF38_1236	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF38_1248	COG1982	Orn Lys Arg decarboxylase major
BF38_125	COG1454	alcohol dehydrogenase
BF38_125	COG1012	belongs to the aldehyde dehydrogenase family
BF38_1250	COG0470	DNA polymerase III
BF38_1251	COG1774	PSP1 C-terminal conserved region
BF38_1253	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF38_1255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF38_1256	COG2002	toxin-antitoxin pair type II binding
BF38_1257	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF38_1257	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF38_1258	COG0084	hydrolase, TatD family'
BF38_1259	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF38_126	COG0626	cystathionine gamma-synthase activity
BF38_1262	COG4466	Protein conserved in bacteria
BF38_1265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF38_1266	COG0251	oxidation-reduction process
BF38_1269	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF38_127	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF38_1272	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF38_1273	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF38_1274	COG2002	toxin-antitoxin pair type II binding
BF38_1275	COG2244	polysaccharide biosynthetic process
BF38_1276	COG3956	TIGRFAM MazG family protein
BF38_1277	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF38_1281	COG1098	S1 RNA binding domain
BF38_1284	COG2208	phosphoserine phosphatase activity
BF38_1287	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF38_1290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF38_1291	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF38_1292	COG0512	Glutamine amidotransferase of anthranilate synthase
BF38_1293	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF38_1294	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF38_1295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF38_1296	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF38_1297	COG1396	sequence-specific DNA binding
BF38_1298	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF38_13	COG0626	cystathionine gamma-synthase activity
BF38_1318	COG3880	PFAM UvrB UvrC protein
BF38_132	COG0768	penicillin binding
BF38_1320	COG0542	response to heat
BF38_1321	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF38_1323	COG4956	integral membrane protein (PIN domain superfamily)
BF38_1327	COG1045	serine acetyltransferase
BF38_1330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF38_1331	COG3688	RNA-binding protein containing a PIN domain
BF38_1333	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF38_1334	COG0250	Participates in transcription elongation, termination and antitermination
BF38_1339	COG2813	Specifically methylates the guanine in position
BF38_1342	COG1358	cellular component organization or biogenesis
BF38_1363	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF38_1368	COG0201	protein transport
BF38_1370	COG0024	Methionine aminopeptidase
BF38_1372	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF38_1378	COG1122	ATPase activity
BF38_1379	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF38_138	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF38_1380	COG0101	tRNA pseudouridine synthase activity
BF38_1384	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF38_1385	COG0489	protein tyrosine kinase activity
BF38_1387	COG2194	sulfuric ester hydrolase activity
BF38_1388	COG0726	polysaccharide deacetylase
BF38_14	COG0626	cystathionine gamma-synthase activity
BF38_1405	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF38_1406	COG4856	YbbR-like protein
BF38_1408	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF38_1409	COG0596	Alpha beta hydrolase
BF38_1413	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF38_1414	COG0823	Involved in the tonB-independent uptake of proteins
BF38_1414	COG1506	peptidase
BF38_1414	COG4946	Tricorn protease homolog
BF38_1422	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_1423	COG2011	ABC-type metal ion transport system permease component
BF38_1424	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF38_1425	COG1464	Belongs to the NlpA lipoprotein family
BF38_1428	COG0277	FAD linked oxidase domain protein
BF38_1429	COG2271	Major facilitator Superfamily
BF38_1431	COG2814	Major facilitator Superfamily
BF38_1434	COG0601	transmembrane transport
BF38_1435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF38_1436	COG0444	Belongs to the ABC transporter superfamily
BF38_1437	COG4608	Belongs to the ABC transporter superfamily
BF38_1438	COG4166	transmembrane transport
BF38_144	COG0628	permease
BF38_1440	COG2207	Transcriptional regulator
BF38_1442	COG1309	transcriptional regulator
BF38_1444	COG4166	transmembrane transport
BF38_1445	COG4166	transmembrane transport
BF38_1446	COG0656	L-ascorbic acid biosynthetic process
BF38_1447	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF38_1450	COG4149	molybdate abc transporter
BF38_1451	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF38_1452	COG1910	domain protein
BF38_1456	COG0697	spore germination
BF38_1459	COG0204	Acyl-transferase
BF38_1461	COG1609	Transcriptional regulator
BF38_1463	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_1466	COG0084	hydrolase, TatD family'
BF38_1467	COG5298	Protein conserved in bacteria
BF38_1471	COG0488	(ABC) transporter
BF38_1472	COG4585	Histidine kinase
BF38_1473	COG2197	response regulator
BF38_1474	COG1131	(ABC) transporter
BF38_1475	COG1511	domain protein
BF38_1475	COG0842	Transport permease protein
BF38_1476	COG0842	Transport permease protein
BF38_1479	COG0747	negative chemotaxis
BF38_148	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF38_1480	COG0601	transmembrane transport
BF38_1481	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF38_1482	COG0444	Belongs to the ABC transporter superfamily
BF38_1483	COG4608	Belongs to the ABC transporter superfamily
BF38_1484	COG0561	phosphatase activity
BF38_1489	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF38_1490	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF38_1494	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF38_1496	COG0457	Tetratricopeptide repeat
BF38_1496	COG0705	Rhomboid family
BF38_1497	COG4294	response to UV
BF38_1499	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF38_1500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF38_1501	COG0864	Transcriptional regulator
BF38_1502	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF38_1503	COG2183	response to ionizing radiation
BF38_151	COG1104	cysteine desulfurase activity
BF38_152	COG1959	2 iron, 2 sulfur cluster binding
BF38_1522	COG0802	atpase or kinase
BF38_1523	COG1214	PFAM Peptidase M22, glycoprotease
BF38_1524	COG0456	acetyltransferase
BF38_1525	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF38_1526	COG0488	(ABC) transporter
BF38_1529	COG1266	CAAX protease self-immunity
BF38_153	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF38_1533	COG2252	PERMEase
BF38_1535	COG5002	protein histidine kinase activity
BF38_1541	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF38_1549	COG2226	methyltransferase
BF38_155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF38_1553	COG1215	transferase activity, transferring glycosyl groups
BF38_1561	COG2205	protein histidine kinase activity
BF38_1562	COG0745	RESPONSE REGULATOR receiver
BF38_1567	COG0697	spore germination
BF38_157	COG0124	histidyl-tRNA synthetase
BF38_1573	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF38_1574	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF38_1575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF38_1577	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF38_1580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF38_1582	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF38_1584	COG0151	Belongs to the GarS family
BF38_1589	COG0210	DNA helicase
BF38_1591	COG4851	CamS sex pheromone cAM373 precursor
BF38_1595	COG1335	isochorismatase
BF38_1596	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF38_1597	COG2011	ABC-type metal ion transport system permease component
BF38_1598	COG1464	Belongs to the NlpA lipoprotein family
BF38_1601	COG0003	Pfam Anion-transporting ATPase
BF38_1602	COG1846	Transcriptional regulator
BF38_1603	COG4682	membrane
BF38_1607	COG1597	lipid kinase activity
BF38_1608	COG0546	phosphoglycolate phosphatase activity
BF38_1609	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF38_161	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF38_1611	COG1012	belongs to the aldehyde dehydrogenase family
BF38_1612	COG2076	Multidrug Resistance protein
BF38_1613	COG2309	aminopeptidase activity
BF38_1616	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF38_1617	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF38_1618	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF38_1620	COG4807	Protein conserved in bacteria
BF38_1626	COG1473	amidohydrolase
BF38_1629	COG0450	alkyl hydroperoxide reductase
BF38_163	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF38_163	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF38_1630	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BF38_1632	COG0235	Class ii aldolase
BF38_1633	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_1634	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_1635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_1638	COG0166	Belongs to the GPI family
BF38_164	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF38_1644	COG5002	protein histidine kinase activity
BF38_1648	COG3541	Predicted nucleotidyltransferase
BF38_165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF38_165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF38_1651	COG0723	plastoquinol--plastocyanin reductase activity
BF38_1651	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF38_1653	COG0765	amino acid transport
BF38_1654	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF38_1656	COG0840	transmembrane signaling receptor activity
BF38_1664	COG0366	Alpha amylase catalytic
BF38_1665	COG1263	PTS System
BF38_1665	COG2190	(PTS) system
BF38_1665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF38_167	COG2244	polysaccharide biosynthetic process
BF38_1671	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF38_1674	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF38_1676	COG1116	anion transmembrane transporter activity
BF38_1677	COG0488	(ABC) transporter
BF38_168	COG2323	membrane
BF38_1688	COG2270	Major facilitator Superfamily
BF38_1694	COG2310	stress, protein
BF38_1695	COG2310	stress, protein
BF38_1696	COG2310	stress, protein
BF38_1697	COG0861	Integral membrane protein TerC family
BF38_1699	COG3853	Toxic anion resistance protein (TelA)
BF38_170	COG1862	Preprotein translocase
BF38_1702	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF38_1704	COG1295	ribonuclease BN
BF38_1705	COG2217	Heavy metal translocating P-type atpase
BF38_1706	COG0697	spore germination
BF38_1709	COG0681	Belongs to the peptidase S26 family
BF38_1711	COG0586	Pfam SNARE associated Golgi protein
BF38_1714	COG3871	stress protein (general stress protein 26)
BF38_1715	COG0387	Pfam Sodium calcium exchanger
BF38_1717	COG0535	radical SAM domain protein
BF38_1721	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF38_1722	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF38_1723	COG0101	tRNA pseudouridine synthase activity
BF38_1725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF38_1730	COG2066	Belongs to the glutaminase family
BF38_1731	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF38_1731	COG1263	PTS System
BF38_1732	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF38_1735	COG0463	Glycosyl transferase, family 2
BF38_1737	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF38_1737	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF38_1740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF38_1744	COG1228	amidohydrolase
BF38_1745	COG1090	epimerase
BF38_1751	COG1988	membrane-bound metal-dependent
BF38_1752	COG1194	a g-specific adenine glycosylase
BF38_1757	COG1132	(ABC) transporter
BF38_1758	COG4129	membrane
BF38_1759	COG0070	glutamate synthase
BF38_1759	COG0069	glutamate synthase activity
BF38_1759	COG0067	glutamate synthase
BF38_176	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF38_1761	COG4555	ABC transporter
BF38_1765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF38_1766	COG0735	belongs to the Fur family
BF38_1790	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF38_1791	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF38_1793	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF38_1795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF38_1798	COG2766	serine protein kinase
BF38_18	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_1803	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF38_1805	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF38_1806	COG2268	Band 7 protein
BF38_1808	COG3290	protein histidine kinase activity
BF38_1809	COG4565	transcriptional regulatory protein
BF38_1810	COG2851	Citrate transporter
BF38_1814	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF38_1815	COG3842	ATPase activity
BF38_1816	COG1175	transmembrane transport
BF38_1817	COG0395	ABC-type sugar transport system, permease component
BF38_1819	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF38_182	COG0157	Belongs to the NadC ModD family
BF38_1820	COG0745	RESPONSE REGULATOR receiver
BF38_1821	COG5002	protein histidine kinase activity
BF38_1823	COG4990	cell redox homeostasis
BF38_1825	COG3290	protein histidine kinase activity
BF38_1826	COG4565	transcriptional regulatory protein
BF38_1827	COG3493	citrate carrier protein
BF38_1828	COG0281	malic enzyme
BF38_183	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF38_1831	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_1833	COG5002	protein histidine kinase activity
BF38_1834	COG0745	RESPONSE REGULATOR receiver
BF38_1836	COG0454	-acetyltransferase
BF38_1836	COG0456	acetyltransferase
BF38_1837	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF38_1838	COG3383	formate dehydrogenase (NAD+) activity
BF38_1839	COG2427	Protein of unknown function (DUF1641)
BF38_184	COG1104	cysteine desulfurase activity
BF38_1842	COG0531	amino acid
BF38_1843	COG0640	Transcriptional regulator
BF38_1844	COG2217	Heavy metal translocating P-type atpase
BF38_1845	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF38_1848	COG3227	Zinc metalloprotease (Elastase)
BF38_185	COG1827	regulation of RNA biosynthetic process
BF38_1852	COG2720	vancomycin resistance protein
BF38_1853	COG1316	TRANSCRIPTIONal
BF38_1854	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF38_1855	COG0346	lactoylglutathione lyase activity
BF38_1856	COG1253	flavin adenine dinucleotide binding
BF38_1857	COG1027	Aspartate ammonia-lyase
BF38_1858	COG1620	l-lactate permease
BF38_186	COG2258	MOSC domain
BF38_1861	COG3104	oligopeptide transport
BF38_1862	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_1863	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_1864	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_1866	COG0156	8-amino-7-oxononanoate synthase activity
BF38_1867	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF38_1868	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BF38_187	COG0077	Prephenate dehydratase
BF38_1870	COG4548	von Willebrand factor, type A
BF38_1871	COG0714	Associated with various cellular activities
BF38_1872	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF38_1876	COG0531	amino acid
BF38_1877	COG2188	Transcriptional regulator
BF38_1878	COG1263	PTS System
BF38_1878	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF38_1879	COG0366	Alpha amylase catalytic
BF38_188	COG0577	efflux transmembrane transporter activity
BF38_1882	COG0697	spore germination
BF38_1884	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF38_1885	COG1115	amino acid carrier protein
BF38_1886	COG1126	abc transporter atp-binding protein
BF38_1887	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF38_1888	COG0765	amino acid transport
BF38_1889	COG0765	amino acid transport
BF38_189	COG0577	efflux transmembrane transporter activity
BF38_1890	COG0833	amino acid
BF38_1895	COG2378	regulation of single-species biofilm formation
BF38_1896	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF38_1897	COG5002	protein histidine kinase activity
BF38_190	COG1136	(ABC) transporter
BF38_1900	COG0659	secondary active sulfate transmembrane transporter activity
BF38_1903	COG0747	negative chemotaxis
BF38_1905	COG0601	transmembrane transport
BF38_1906	COG4608	Belongs to the ABC transporter superfamily
BF38_1908	COG2271	Major facilitator Superfamily
BF38_1909	COG1846	Transcriptional regulator
BF38_191	COG5002	protein histidine kinase activity
BF38_1910	COG0477	Major facilitator Superfamily
BF38_1911	COG1609	Transcriptional regulator
BF38_1912	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF38_1914	COG1129	ABC transporter
BF38_1915	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF38_1916	COG1879	ABC-type sugar transport system periplasmic component
BF38_1917	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF38_192	COG0745	RESPONSE REGULATOR receiver
BF38_1920	COG1063	alcohol dehydrogenase
BF38_1923	COG3568	Endonuclease Exonuclease Phosphatase
BF38_1929	COG0840	transmembrane signaling receptor activity
BF38_1930	COG3584	3D domain protein
BF38_1930	COG1388	LysM domain
BF38_1931	COG1476	TRANSCRIPTIONal
BF38_1934	COG3104	oligopeptide transport
BF38_1935	COG1114	Component of the transport system for branched-chain amino acids
BF38_1938	COG1113	amino acid transport
BF38_1939	COG2252	PERMEase
BF38_194	COG3290	protein histidine kinase activity
BF38_1942	COG2153	protein acetylation
BF38_1944	COG0475	glutathione-regulated potassium exporter activity
BF38_1944	COG0569	domain protein
BF38_1947	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF38_1948	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF38_1949	COG4990	cell redox homeostasis
BF38_1952	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF38_1953	COG0697	spore germination
BF38_1954	COG0531	amino acid
BF38_1956	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF38_1957	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF38_1958	COG1918	ferrous iron import across plasma membrane
BF38_1958	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF38_1959	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF38_196	COG2868	ribosomal protein
BF38_1960	COG0573	inorganic phosphate transmembrane transporter activity
BF38_1961	COG0581	inorganic phosphate transmembrane transporter activity
BF38_1963	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF38_198	COG1530	ribonuclease E activity
BF38_1988	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF38_199	COG1994	Peptidase M50
BF38_1992	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF38_1993	COG1116	anion transmembrane transporter activity
BF38_1994	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF38_1995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF38_1996	COG0352	thiamine-phosphate diphosphorylase activity
BF38_1997	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF38_1998	COG2104	thiamine diphosphate biosynthetic process
BF38_20	COG1940	carbohydrate kinase activity
BF38_200	COG0739	heme binding
BF38_2000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF38_2001	COG0351	phosphomethylpyrimidine kinase
BF38_2008	COG2205	protein histidine kinase activity
BF38_2009	COG2814	Major facilitator Superfamily
BF38_201	COG2894	cell division
BF38_2010	COG1846	Transcriptional regulator
BF38_2013	COG2252	PERMEase
BF38_2014	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_2015	COG1376	ErfK ybiS ycfS ynhG family protein
BF38_2018	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF38_2019	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF38_2026	COG0778	Nitroreductase
BF38_2027	COG2719	SpoVR family
BF38_2029	COG3591	Belongs to the peptidase S1B family
BF38_2031	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF38_2032	COG1937	Protein conserved in bacteria
BF38_2033	COG0425	Belongs to the sulfur carrier protein TusA family
BF38_2033	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF38_2034	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_2034	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF38_2035	COG0425	Belongs to the sulfur carrier protein TusA family
BF38_2036	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF38_2038	COG2210	Belongs to the sulfur carrier protein TusA family
BF38_2039	COG0730	response to heat
BF38_204	COG1792	Involved in formation and maintenance of cell shape
BF38_2041	COG1316	TRANSCRIPTIONal
BF38_2042	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF38_2043	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF38_2046	COG3711	transcriptional antiterminator
BF38_2046	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF38_2047	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF38_2048	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF38_205	COG1077	Cell shape determining protein MreB Mrl
BF38_2052	COG1388	LysM domain
BF38_2052	COG3584	3D domain protein
BF38_2053	COG0577	efflux transmembrane transporter activity
BF38_2054	COG1136	(ABC) transporter
BF38_2056	COG5522	Integral membrane protein (intg_mem_TP0381)
BF38_2059	COG1114	Component of the transport system for branched-chain amino acids
BF38_2060	COG3546	catalase activity
BF38_2067	COG0586	Pfam SNARE associated Golgi protein
BF38_2074	COG0531	amino acid
BF38_2075	COG0475	glutathione-regulated potassium exporter activity
BF38_2077	COG1737	Transcriptional regulator
BF38_2079	COG1263	PTS System
BF38_2079	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF38_2081	COG2259	Doxx family
BF38_2085	COG1522	sequence-specific DNA binding
BF38_2087	COG2076	Multidrug Resistance protein
BF38_2088	COG2076	Multidrug Resistance protein
BF38_2089	COG1309	transcriptional regulator
BF38_209	COG0285	dihydrofolate synthase activity
BF38_2090	COG2814	Major facilitator Superfamily
BF38_2091	COG1733	regulation of RNA biosynthetic process
BF38_2093	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF38_2095	COG4533	DNA binding
BF38_2096	COG2211	Major facilitator Superfamily
BF38_2098	COG0693	protein deglycase activity
BF38_2099	COG0693	protein deglycase activity
BF38_2099	COG0753	catalase activity
BF38_21	COG4483	Protein conserved in bacteria
BF38_210	COG0525	valine-tRNA ligase activity
BF38_2101	COG0531	amino acid
BF38_2102	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF38_2104	COG1012	belongs to the aldehyde dehydrogenase family
BF38_2105	COG1132	(ABC) transporter
BF38_2106	COG1132	(ABC) transporter
BF38_2107	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF38_2108	COG0765	amino acid transport
BF38_2109	COG1126	abc transporter atp-binding protein
BF38_2112	COG0189	ligase activity
BF38_2118	COG0028	Belongs to the TPP enzyme family
BF38_2119	COG3527	Alpha-acetolactate decarboxylase
BF38_212	COG1388	LysM domain
BF38_2121	COG0561	phosphatase activity
BF38_2123	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF38_2123	COG3409	Peptidoglycan-binding domain 1 protein
BF38_2124	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF38_2127	COG0659	secondary active sulfate transmembrane transporter activity
BF38_2131	COG0653	protein targeting
BF38_2132	COG2244	polysaccharide biosynthetic process
BF38_2134	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF38_2135	COG4196	transglutaminase domain protein
BF38_2138	COG1696	Membrane protein involved in D-alanine export
BF38_214	COG0113	porphobilinogen synthase activity
BF38_2141	COG1024	Enoyl-CoA hydratase
BF38_2145	COG1363	Peptidase, m42
BF38_215	COG1587	Uroporphyrinogen-III synthase
BF38_2156	COG0601	transmembrane transport
BF38_2157	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF38_2158	COG0444	Belongs to the ABC transporter superfamily
BF38_2159	COG4608	Belongs to the ABC transporter superfamily
BF38_2162	COG0477	Major facilitator Superfamily
BF38_2163	COG3290	protein histidine kinase activity
BF38_2164	COG4565	transcriptional regulatory protein
BF38_2165	COG3181	Tripartite tricarboxylate transporter family receptor
BF38_217	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF38_2171	COG0419	ATPase involved in DNA repair
BF38_2173	COG1104	cysteine desulfurase activity
BF38_2180	COG0789	Transcriptional regulator
BF38_2180	COG4978	Transcriptional regulator
BF38_2183	COG0305	Participates in initiation and elongation during chromosome replication
BF38_2188	COG0477	Major facilitator Superfamily
BF38_219	COG1846	Transcriptional regulator
BF38_22	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF38_220	COG1764	response to oxidative stress
BF38_2204	COG1183	phosphatidylcholine synthase activity
BF38_2210	COG2376	Dihydroxyacetone kinase
BF38_2212	COG2376	Dihydroxyacetone kinase
BF38_2214	COG3437	response regulator, receiver
BF38_2214	COG2770	Histidine kinase
BF38_2224	COG3237	CsbD-like
BF38_2229	COG1191	sigma factor activity
BF38_223	COG1067	ATP-dependent peptidase activity
BF38_223	COG0470	DNA polymerase III
BF38_2231	COG2208	phosphoserine phosphatase activity
BF38_2232	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF38_2233	COG2198	Histidine kinase
BF38_2233	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF38_2233	COG0784	Response regulator, receiver
BF38_2233	COG2205	protein histidine kinase activity
BF38_2238	COG0393	Putative heavy-metal-binding
BF38_2246	COG0420	3'-5' exonuclease activity
BF38_2247	COG4717	serine-type aminopeptidase activity
BF38_2251	COG5444	nuclease activity
BF38_2254	COG0346	lactoylglutathione lyase activity
BF38_2255	COG0346	lactoylglutathione lyase activity
BF38_2256	COG0457	Tetratricopeptide repeat
BF38_2258	COG2267	carboxylic ester hydrolase activity
BF38_2262	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF38_2263	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF38_2265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF38_2270	COG0772	Belongs to the SEDS family
BF38_2273	COG0477	Major facilitator Superfamily
BF38_2274	COG0477	Major facilitator Superfamily
BF38_2276	COG3973	AAA domain
BF38_2277	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF38_2281	COG4980	gas vesicle protein
BF38_2282	COG0537	adenosine 5'-monophosphoramidase activity
BF38_2283	COG1131	(ABC) transporter
BF38_2284	COG4473	ABC transporter
BF38_2295	COG1309	transcriptional regulator
BF38_2297	COG3402	PFAM membrane-flanked domain
BF38_2298	COG3428	Bacterial PH domain
BF38_2307	COG3402	PFAM membrane-flanked domain
BF38_2308	COG3428	Bacterial PH domain
BF38_2309	COG2329	Antibiotic biosynthesis monooxygenase
BF38_2310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF38_2318	COG1309	transcriptional regulator
BF38_2319	COG1511	domain protein
BF38_2323	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
BF38_2325	COG2378	regulation of single-species biofilm formation
BF38_2326	COG1609	Transcriptional regulator
BF38_2328	COG1234	tRNA 3'-trailer cleavage
BF38_2329	COG0095	Lipoate-protein ligase
BF38_2331	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_234	COG0622	Phosphoesterase
BF38_2341	COG1408	metallophosphoesterase
BF38_2343	COG1078	dGTPase activity
BF38_2345	COG1595	DNA-templated transcription, initiation
BF38_2346	COG2207	Transcriptional regulator
BF38_2346	COG3708	Transcriptional regulator
BF38_2349	COG2205	protein histidine kinase activity
BF38_235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF38_2350	COG0745	RESPONSE REGULATOR receiver
BF38_2354	COG0501	Belongs to the peptidase M48B family
BF38_2355	COG0840	transmembrane signaling receptor activity
BF38_2356	COG0697	spore germination
BF38_2359	COG0497	DNA recombination
BF38_2360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF38_2361	COG2224	Isocitrate lyase
BF38_2363	COG1278	Cold shock
BF38_2366	COG4903	ComK protein
BF38_2368	COG0398	Pfam SNARE associated Golgi protein
BF38_237	COG5401	PFAM Sporulation and spore germination
BF38_2380	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF38_2385	COG0367	asparagine synthase
BF38_2387	COG0753	catalase activity
BF38_2388	COG0004	ammonium transporteR
BF38_2392	COG2996	Protein conserved in bacteria
BF38_2397	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_24	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF38_2400	COG0561	phosphatase activity
BF38_2402	COG0542	response to heat
BF38_2404	COG2267	carboxylic ester hydrolase activity
BF38_2407	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF38_2408	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF38_2409	COG5504	Zn-dependent protease
BF38_241	COG1309	transcriptional regulator
BF38_2411	COG0180	Tryptophanyl-tRNA synthetase
BF38_2413	COG4166	transmembrane transport
BF38_2414	COG0601	transmembrane transport
BF38_2415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF38_2416	COG0444	Belongs to the ABC transporter superfamily
BF38_2417	COG4608	Belongs to the ABC transporter superfamily
BF38_2418	COG0534	Mate efflux family protein
BF38_2419	COG4166	transmembrane transport
BF38_2421	COG1393	Belongs to the ArsC family
BF38_2422	COG0861	Integral membrane protein TerC family
BF38_2423	COG4862	establishment of competence for transformation
BF38_2424	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF38_2426	COG1164	Oligoendopeptidase f
BF38_2429	COG2346	COG2346, Truncated hemoglobins
BF38_2430	COG4116	CYTH
BF38_2432	COG2357	RelA SpoT domain protein
BF38_2434	COG0564	pseudouridine synthase activity
BF38_2437	COG0772	Belongs to the SEDS family
BF38_2438	COG1216	Glycosyl transferase, family 2
BF38_244	COG2197	response regulator
BF38_2442	COG0463	Glycosyl transferase, family 2
BF38_2442	COG0457	Tetratricopeptide repeat
BF38_2446	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF38_2449	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF38_245	COG2233	PERMEase
BF38_2457	COG2153	protein acetylation
BF38_2459	COG2382	esterase
BF38_2462	COG5492	domain, Protein
BF38_2463	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF38_2465	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF38_2465	COG0512	Glutamine amidotransferase of anthranilate synthase
BF38_247	COG0402	S-adenosylhomocysteine deaminase activity
BF38_2472	COG1620	l-lactate permease
BF38_2473	COG5634	Uncharacterized conserved protein (DUF2278)
BF38_248	COG0402	S-adenosylhomocysteine deaminase activity
BF38_2483	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF38_2485	COG1476	TRANSCRIPTIONal
BF38_2496	COG2226	methyltransferase
BF38_2498	COG1686	Belongs to the peptidase S11 family
BF38_2499	COG0681	Belongs to the peptidase S26 family
BF38_25	COG0704	Plays a role in the regulation of phosphate uptake
BF38_2505	COG1012	belongs to the aldehyde dehydrogenase family
BF38_2507	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF38_2508	COG1177	transmembrane transport
BF38_2509	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF38_2511	COG2409	Drug exporters of the RND superfamily
BF38_2513	COG0564	pseudouridine synthase activity
BF38_2515	COG2340	Cysteine-rich secretory protein family
BF38_2516	COG0247	lactate metabolic process
BF38_2517	COG0277	FAD linked oxidase domain protein
BF38_2518	COG3835	regulator
BF38_252	COG0444	Belongs to the ABC transporter superfamily
BF38_2520	COG0745	RESPONSE REGULATOR receiver
BF38_2521	COG5002	protein histidine kinase activity
BF38_2522	COG2186	Transcriptional regulator
BF38_2526	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF38_2528	COG2116	formate transmembrane transporter activity
BF38_2529	COG0861	Integral membrane protein TerC family
BF38_253	COG4608	Belongs to the ABC transporter superfamily
BF38_2530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF38_2532	COG2030	dehydratase
BF38_2536	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_2537	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF38_2539	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF38_254	COG3275	phosphorelay sensor kinase activity
BF38_2542	COG1840	ABC-type Fe3 transport system, periplasmic component
BF38_2543	COG3842	ATPase activity
BF38_2548	COG1349	DNA-binding transcription factor activity
BF38_255	COG3279	Response regulator of the LytR AlgR family
BF38_2551	COG0235	Class ii aldolase
BF38_2553	COG2861	carbohydrate metabolic process
BF38_2555	COG3852	Histidine kinase
BF38_2556	COG1846	Transcriptional regulator
BF38_2558	COG2318	DinB family
BF38_2560	COG5002	protein histidine kinase activity
BF38_2562	COG0720	synthase
BF38_2565	COG4873	Protein conserved in bacteria
BF38_257	COG1983	PspC domain protein
BF38_2571	COG1780	Probably involved in ribonucleotide reductase function
BF38_2572	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF38_2574	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF38_2575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF38_2576	COG1725	Transcriptional regulator
BF38_2577	COG1131	(ABC) transporter
BF38_2579	COG1131	(ABC) transporter
BF38_258	COG1396	sequence-specific DNA binding
BF38_2580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF38_2581	COG1266	CAAX protease self-immunity
BF38_2583	COG1522	sequence-specific DNA binding
BF38_2585	COG1335	isochorismatase
BF38_2587	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF38_2588	COG2070	2-Nitropropane dioxygenase
BF38_2589	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF38_259	COG0697	spore germination
BF38_2591	COG1696	Membrane protein involved in D-alanine export
BF38_2596	COG0716	FMN binding
BF38_2599	COG3173	Aminoglycoside phosphotransferase
BF38_26	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF38_2603	COG0534	Mate efflux family protein
BF38_2604	COG1968	undecaprenyl-diphosphatase activity
BF38_2607	COG1846	Transcriptional regulator
BF38_2609	COG1301	dicarboxylic acid transport
BF38_261	COG1959	2 iron, 2 sulfur cluster binding
BF38_2610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF38_2611	COG4709	membrane
BF38_2612	COG3874	Sporulation protein YtfJ
BF38_2616	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF38_2617	COG0028	Belongs to the TPP enzyme family
BF38_2618	COG0440	acetolactate synthase activity
BF38_2619	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF38_262	COG1668	transmembrane transport
BF38_2621	COG0473	3-isopropylmalate dehydrogenase activity
BF38_263	COG4152	abc transporter atp-binding protein
BF38_2633	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF38_2636	COG1183	phosphatidylcholine synthase activity
BF38_2637	COG1368	sulfuric ester hydrolase activity
BF38_2639	COG0019	diaminopimelate decarboxylase activity
BF38_264	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF38_2643	COG0529	Catalyzes the synthesis of activated sulfate
BF38_2644	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF38_2648	COG1648	precorrin-2 dehydrogenase activity
BF38_2649	COG0733	neurotransmitter:sodium symporter activity
BF38_265	COG1360	Flagellar Motor Protein
BF38_2653	COG1757	Na H antiporter
BF38_2656	COG4758	membrane
BF38_2657	COG4585	Histidine kinase
BF38_2658	COG2197	response regulator
BF38_266	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF38_2660	COG1114	Component of the transport system for branched-chain amino acids
BF38_2662	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF38_267	COG1876	peptidase activity
BF38_2670	COG0730	response to heat
BF38_2671	COG0306	phosphate transporter
BF38_2672	COG1392	Phosphate transport regulator
BF38_2673	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF38_2676	COG3852	Histidine kinase
BF38_2677	COG1801	Protein of unknown function DUF72
BF38_2679	COG0582	viral genome integration into host DNA
BF38_268	COG0824	Thioesterase
BF38_2680	COG5002	protein histidine kinase activity
BF38_2684	COG0392	lysyltransferase activity
BF38_2684	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF38_2687	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF38_2688	COG1686	Belongs to the peptidase S11 family
BF38_2689	COG2715	membrane protein required for spore maturation
BF38_269	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF38_2690	COG0700	Nucleoside recognition
BF38_2691	COG1187	pseudouridine synthase activity
BF38_2693	COG1333	cytochrome c biogenesis protein
BF38_2694	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF38_2695	COG0745	RESPONSE REGULATOR receiver
BF38_2696	COG5002	protein histidine kinase activity
BF38_2697	COG2096	Adenosyltransferase
BF38_2698	COG4942	peptidase
BF38_27	COG0581	inorganic phosphate transmembrane transporter activity
BF38_270	COG1053	succinate dehydrogenase
BF38_2700	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF38_2701	COG1141	Ferredoxin
BF38_2703	COG0514	ATP-dependent DNA helicase (RecQ)
BF38_2704	COG1266	CAAX protease self-immunity
BF38_2706	COG1408	metallophosphoesterase
BF38_2708	COG4862	establishment of competence for transformation
BF38_2709	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF38_271	COG2009	succinate dehydrogenase
BF38_2713	COG0492	ferredoxin-NADP+ reductase activity
BF38_2714	COG0252	asparaginase activity
BF38_272	COG1719	4-vinyl reductase, 4VR
BF38_2728	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF38_2731	COG0142	geranyltranstransferase activity
BF38_2733	COG0142	geranyltranstransferase activity
BF38_2734	COG0105	UTP biosynthetic process
BF38_2737	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF38_2738	COG0457	Tetratricopeptide repeat
BF38_274	COG3118	belongs to the thioredoxin family
BF38_2742	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF38_2744	COG4347	Protein of unknown function (DUF1405)
BF38_2747	COG2738	Putative neutral zinc metallopeptidase
BF38_2749	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_275	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF38_2750	COG1694	Mazg nucleotide pyrophosphohydrolase
BF38_2753	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF38_2754	COG0438	transferase activity, transferring glycosyl groups
BF38_276	COG2086	electron transfer activity
BF38_2761	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF38_2761	COG1199	ATP-dependent helicase activity
BF38_2765	COG3935	DnaD domain protein
BF38_2766	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF38_2768	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF38_2768	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF38_277	COG1024	Enoyl-CoA hydratase
BF38_2779	COG0116	Belongs to the methyltransferase superfamily
BF38_278	COG1309	transcriptional regulator
BF38_2781	COG1199	ATP-dependent helicase activity
BF38_2782	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF38_2784	COG3173	Aminoglycoside phosphotransferase
BF38_2785	COG0024	Methionine aminopeptidase
BF38_2787	COG2233	PERMEase
BF38_2788	COG2311	Membrane
BF38_279	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_2790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF38_2792	COG0456	acetyltransferase
BF38_2797	COG0754	glutathionylspermidine amidase activity
BF38_28	COG0573	inorganic phosphate transmembrane transporter activity
BF38_2800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF38_2805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF38_2808	COG1215	transferase activity, transferring glycosyl groups
BF38_2809	COG0438	transferase activity, transferring glycosyl groups
BF38_2813	COG0454	-acetyltransferase
BF38_2817	COG0328	RNA-DNA hybrid ribonuclease activity
BF38_2824	COG3403	YqcI/YcgG family
BF38_2825	COG1280	lysine exporter protein (LysE YggA)
BF38_2828	COG3162	membrane
BF38_2829	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF38_283	COG2318	DinB family
BF38_2830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF38_2832	COG0475	glutathione-regulated potassium exporter activity
BF38_2833	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF38_2834	COG4978	Transcriptional regulator
BF38_2834	COG0789	Transcriptional regulator
BF38_2836	COG2323	membrane
BF38_2837	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF38_2848	COG1923	regulation of RNA biosynthetic process
BF38_2850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF38_2851	COG1360	Flagellar Motor Protein
BF38_2852	COG2201	protein-glutamate methylesterase activity
BF38_2853	COG2198	Histidine kinase
BF38_2853	COG0643	Histidine kinase
BF38_2854	COG1776	CheC inhibitor of MCP methylation
BF38_2854	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF38_2857	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF38_2861	COG1256	bacterial-type flagellum assembly
BF38_2862	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF38_2863	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BF38_2866	COG1815	bacterial-type flagellum-dependent cell motility
BF38_2867	COG1558	bacterial-type flagellum-dependent cell motility
BF38_2868	COG1677	Flagellar hook-basal body complex protein FliE
BF38_2869	COG1766	The M ring may be actively involved in energy transduction
BF38_2870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF38_2872	COG1157	protein secretion by the type III secretion system
BF38_2879	COG0784	Response regulator, receiver
BF38_2879	COG0835	chemotaxis
BF38_288	COG1131	(ABC) transporter
BF38_2881	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF38_2882	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF38_2883	COG0741	lytic transglycosylase activity
BF38_2885	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF38_2886	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF38_2886	COG1776	CheC inhibitor of MCP methylation
BF38_2888	COG1338	Plays a role in the flagellum-specific transport system
BF38_2889	COG1987	bacterial-type flagellum assembly
BF38_289	COG2205	protein histidine kinase activity
BF38_2891	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF38_2892	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF38_2893	COG1419	protein localization to endoplasmic reticulum
BF38_2894	COG4786	Flagellar basal body rod
BF38_2895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF38_29	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF38_290	COG0745	RESPONSE REGULATOR receiver
BF38_2902	COG2329	Antibiotic biosynthesis monooxygenase
BF38_2908	COG3842	ATPase activity
BF38_2909	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF38_2910	COG1177	transmembrane transport
BF38_2911	COG1234	tRNA 3'-trailer cleavage
BF38_2916	COG1686	Belongs to the peptidase S11 family
BF38_292	COG4895	conserved protein (DUF2196)
BF38_2922	COG1846	Transcriptional regulator
BF38_2924	COG0367	asparagine synthase
BF38_293	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF38_2930	COG1802	Transcriptional regulator
BF38_2931	COG0697	spore germination
BF38_2932	COG0523	cobalamin synthesis protein
BF38_2933	COG0701	Predicted permease
BF38_2935	COG0438	transferase activity, transferring glycosyl groups
BF38_2935	COG1216	Glycosyl transferase, family 2
BF38_2936	COG1757	Na H antiporter
BF38_2937	COG0789	Transcriptional regulator
BF38_2939	COG0114	fumarate hydratase activity
BF38_2943	COG0534	Mate efflux family protein
BF38_2944	COG3340	Belongs to the peptidase S51 family
BF38_2948	COG0785	Cytochrome C biogenesis protein
BF38_2954	COG2733	membrane
BF38_296	COG4509	Sortase family
BF38_2961	COG1131	(ABC) transporter
BF38_2964	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF38_2965	COG0528	UMP kinase activity
BF38_2967	COG1027	Aspartate ammonia-lyase
BF38_2968	COG0281	malic enzyme
BF38_2969	COG4191	Histidine kinase
BF38_297	COG1120	ATPase activity
BF38_2970	COG0784	Response regulator, receiver
BF38_2971	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF38_2981	COG1051	belongs to the nudix hydrolase family
BF38_2982	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF38_2987	COG1966	Carbon starvation protein
BF38_2989	COG0477	Major facilitator Superfamily
BF38_2990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF38_2992	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF38_2993	COG4166	transmembrane transport
BF38_2994	COG2223	nitrite transmembrane transporter activity
BF38_2995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF38_2998	COG2244	polysaccharide biosynthetic process
BF38_2999	COG0733	neurotransmitter:sodium symporter activity
BF38_300	COG5386	Cell surface protein
BF38_3001	COG5566	PFAM Mor transcription activator
BF38_3002	COG2323	membrane
BF38_3006	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF38_3008	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF38_3009	COG0028	Belongs to the TPP enzyme family
BF38_3010	COG0440	acetolactate synthase activity
BF38_3011	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF38_3013	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF38_3018	COG2814	Major facilitator Superfamily
BF38_3019	COG3384	dioxygenase
BF38_302	COG5386	Cell surface protein
BF38_3021	COG3279	Response regulator of the LytR AlgR family
BF38_3022	COG0427	acetyl-CoA hydrolase
BF38_3026	COG1073	alpha beta
BF38_3027	COG0582	viral genome integration into host DNA
BF38_303	COG1114	Component of the transport system for branched-chain amino acids
BF38_3030	COG1396	sequence-specific DNA binding
BF38_3033	COG1396	sequence-specific DNA binding
BF38_304	COG1187	pseudouridine synthase activity
BF38_3040	COG1484	DNA-dependent DNA replication
BF38_3051	COG0662	Cupin 2, conserved barrel domain protein
BF38_3058	COG0582	viral genome integration into host DNA
BF38_3059	COG2323	membrane
BF38_3061	COG1674	ftsk spoiiie
BF38_3061	COG4980	gas vesicle protein
BF38_307	COG1796	DNA polymerase
BF38_307	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF38_3070	COG4626	Terminase
BF38_3070	COG1802	Transcriptional regulator
BF38_3073	COG0740	serine-type endopeptidase activity
BF38_308	COG1286	toxin biosynthetic process
BF38_3085	COG4824	toxin secretion phage lysis holin
BF38_3093	COG4166	transmembrane transport
BF38_3098	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_31	COG0477	Major facilitator Superfamily
BF38_3102	COG1914	H( )-stimulated, divalent metal cation uptake system
BF38_3105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF38_3107	COG0531	amino acid
BF38_3112	COG2390	Transcriptional regulator
BF38_3114	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF38_3115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF38_3121	COG0006	proline dipeptidase activity
BF38_3122	COG2132	Multicopper oxidase
BF38_3129	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF38_3130	COG1114	Component of the transport system for branched-chain amino acids
BF38_3132	COG2372	response to copper ion
BF38_3132	COG1276	copper resistance
BF38_3133	COG4549	nuclear export factor GLE1
BF38_3134	COG0697	spore germination
BF38_3135	COG0583	DNA-binding transcription factor activity
BF38_3136	COG1959	2 iron, 2 sulfur cluster binding
BF38_3137	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF38_3138	COG0778	Nitroreductase
BF38_314	COG0017	Asparaginyl-tRNA synthetase
BF38_3141	COG0628	permease
BF38_3142	COG0039	L-malate dehydrogenase activity
BF38_3143	COG1231	oxidoreductase activity
BF38_3144	COG0523	cobalamin synthesis protein
BF38_3147	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_3148	COG2030	dehydratase
BF38_3149	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF38_315	COG0072	phenylalanine-tRNA ligase activity
BF38_315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF38_3151	COG0411	ABC transporter
BF38_3155	COG0583	DNA-binding transcription factor activity
BF38_3157	COG1942	4-Oxalocrotonate Tautomerase
BF38_3161	COG1271	oxidase subunit
BF38_3162	COG1294	oxidase, subunit
BF38_3163	COG4988	ABC transporter
BF38_3164	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF38_3167	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF38_3168	COG1686	Belongs to the peptidase S11 family
BF38_317	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF38_3170	COG0791	NLP P60 protein
BF38_3170	COG1388	LysM domain
BF38_3172	COG1132	(ABC) transporter
BF38_3173	COG0745	RESPONSE REGULATOR receiver
BF38_3174	COG5002	protein histidine kinase activity
BF38_3176	COG0300	oxidoreductase activity
BF38_3178	COG0726	polysaccharide deacetylase
BF38_3179	COG5658	integral membrane protein
BF38_3182	COG0460	homoserine dehydrogenase
BF38_3187	COG1316	TRANSCRIPTIONal
BF38_3189	COG0745	RESPONSE REGULATOR receiver
BF38_319	COG1418	mRNA catabolic process
BF38_3190	COG5002	protein histidine kinase activity
BF38_3191	COG0726	polysaccharide deacetylase
BF38_3193	COG1285	pathogenesis
BF38_3194	COG1247	-acetyltransferase
BF38_3196	COG4264	IucA IucC family
BF38_3197	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_32	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF38_3200	COG1082	Xylose isomerase domain protein TIM barrel
BF38_3202	COG2814	Major facilitator Superfamily
BF38_3203	COG1279	arginine transmembrane transporter activity
BF38_3205	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF38_3212	COG0577	efflux transmembrane transporter activity
BF38_3213	COG2002	toxin-antitoxin pair type II binding
BF38_3216	COG1404	Belongs to the peptidase S8 family
BF38_3217	COG0640	Transcriptional regulator
BF38_3218	COG0667	Aldo Keto reductase
BF38_3219	COG2814	Major facilitator Superfamily
BF38_3224	COG0840	transmembrane signaling receptor activity
BF38_3227	COG3949	Membrane
BF38_3228	COG0783	Belongs to the Dps family
BF38_3231	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF38_3233	COG1231	oxidoreductase activity
BF38_3235	COG4989	oxidoreductase activity
BF38_3236	COG0523	cobalamin synthesis protein
BF38_3237	COG0456	acetyltransferase
BF38_324	COG2814	Major facilitator Superfamily
BF38_3247	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF38_3247	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF38_3249	COG0702	epimerase
BF38_325	COG1566	PFAM secretion protein HlyD family protein
BF38_3251	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF38_3253	COG4166	transmembrane transport
BF38_3256	COG0406	alpha-ribazole phosphatase activity
BF38_3258	COG5337	Spore coat protein CotH
BF38_3259	COG1051	belongs to the nudix hydrolase family
BF38_326	COG1309	transcriptional regulator
BF38_3260	COG0586	Pfam SNARE associated Golgi protein
BF38_3261	COG2244	polysaccharide biosynthetic process
BF38_3263	COG0701	Predicted permease
BF38_3264	COG3689	TIGRFAM TIGR03943 family protein
BF38_3265	COG1607	acyl-coa hydrolase
BF38_3266	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF38_3269	COG0702	epimerase
BF38_327	COG1363	Peptidase, m42
BF38_3270	COG2839	Protein conserved in bacteria
BF38_3271	COG1253	flavin adenine dinucleotide binding
BF38_3274	COG1114	Component of the transport system for branched-chain amino acids
BF38_3275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF38_3279	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF38_3281	COG1876	peptidase activity
BF38_3283	COG0154	amidase activity
BF38_3284	COG2211	Major facilitator Superfamily
BF38_3288	COG0561	phosphatase activity
BF38_3290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF38_3294	COG1819	glycosyl
BF38_3295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_3296	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_3302	COG0456	acetyltransferase
BF38_331	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF38_3315	COG3874	Sporulation protein YtfJ
BF38_332	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF38_3320	COG2226	methyltransferase
BF38_3324	COG1082	Xylose isomerase domain protein TIM barrel
BF38_3325	COG0346	lactoylglutathione lyase activity
BF38_3327	COG0604	alcohol dehydrogenase
BF38_3328	COG1595	DNA-templated transcription, initiation
BF38_3330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BF38_3334	COG0386	Belongs to the glutathione peroxidase family
BF38_3335	COG1305	Transglutaminase-like
BF38_3336	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF38_3337	COG0714	Associated with various cellular activities
BF38_3338	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF38_3339	COG1140	nitrate reductase beta subunit
BF38_334	COG1484	DNA-dependent DNA replication
BF38_3340	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF38_3341	COG2181	nitrate reductase activity
BF38_3343	COG1959	2 iron, 2 sulfur cluster binding
BF38_3344	COG3118	belongs to the thioredoxin family
BF38_3345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF38_3346	COG4918	Iron-sulphur cluster biosynthesis
BF38_3347	COG1764	response to oxidative stress
BF38_3348	COG1335	isochorismatase
BF38_335	COG3611	Membrane attachment protein
BF38_3351	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF38_3352	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF38_3353	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF38_3354	COG0303	'Molybdopterin
BF38_3355	COG0314	molybdopterin synthase activity
BF38_3357	COG2223	nitrite transmembrane transporter activity
BF38_3359	COG1648	precorrin-2 dehydrogenase activity
BF38_3361	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF38_3361	COG1587	Uroporphyrinogen-III synthase
BF38_3362	COG2146	nitrite reductase [NAD(P)H] activity
BF38_3363	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF38_3364	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF38_337	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF38_3371	COG2359	stage V sporulation protein S
BF38_3375	COG1418	mRNA catabolic process
BF38_3376	COG0488	(ABC) transporter
BF38_3379	COG0629	single-stranded DNA binding
BF38_338	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF38_3380	COG1413	lyase activity
BF38_3383	COG2136	Putative SAM-dependent methyltransferase
BF38_3383	COG2521	methyltransferase
BF38_3384	COG0018	arginyl-trna synthetase
BF38_339	COG0237	dephospho-CoA kinase activity
BF38_3392	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF38_3393	COG0017	Asparaginyl-tRNA synthetase
BF38_3397	COG1674	ftsk spoiiie
BF38_340	COG1971	Probably functions as a manganese efflux pump
BF38_341	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF38_3415	COG1929	Belongs to the glycerate kinase type-1 family
BF38_3416	COG0471	metal ion transport
BF38_3417	COG0745	RESPONSE REGULATOR receiver
BF38_3418	COG3850	Histidine kinase
BF38_3418	COG5002	protein histidine kinase activity
BF38_342	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF38_342	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF38_3421	COG0733	neurotransmitter:sodium symporter activity
BF38_3426	COG2610	gluconate transmembrane transporter activity
BF38_3427	COG1454	alcohol dehydrogenase
BF38_3428	COG1794	racemase activity, acting on amino acids and derivatives
BF38_343	COG5002	protein histidine kinase activity
BF38_3430	COG0456	acetyltransferase
BF38_3431	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF38_3433	COG1131	(ABC) transporter
BF38_3434	COG4473	ABC transporter
BF38_3436	COG0546	phosphoglycolate phosphatase activity
BF38_3439	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF38_344	COG0745	RESPONSE REGULATOR receiver
BF38_3442	COG0768	penicillin binding
BF38_3444	COG0204	Acyl-transferase
BF38_3445	COG1272	protein, Hemolysin III
BF38_3447	COG0805	protein transport
BF38_3449	COG1307	EDD domain protein, DegV family
BF38_3450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF38_3451	COG1999	signal sequence binding
BF38_3452	COG0071	Belongs to the small heat shock protein (HSP20) family
BF38_3453	COG0367	asparagine synthase
BF38_3457	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_3458	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF38_3462	COG1335	isochorismatase
BF38_3463	COG1051	belongs to the nudix hydrolase family
BF38_3464	COG0071	Belongs to the small heat shock protein (HSP20) family
BF38_3465	COG0668	transmembrane transport
BF38_3466	COG2203	Gaf domain
BF38_3466	COG4585	Histidine kinase
BF38_3467	COG2197	response regulator
BF38_3469	COG1737	Transcriptional regulator
BF38_3470	COG1064	alcohol dehydrogenase
BF38_3475	COG1070	Carbohydrate kinase
BF38_3482	COG1125	glycine betaine transport
BF38_3482	COG0517	IMP dehydrogenase activity
BF38_3483	COG1174	glycine betaine transport
BF38_349	COG0538	isocitrate dehydrogenase activity
BF38_3490	COG1253	flavin adenine dinucleotide binding
BF38_3491	COG1012	belongs to the aldehyde dehydrogenase family
BF38_3492	COG5506	Protein of unknown function (DUF1694)
BF38_3495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF38_3496	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF38_3497	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF38_3498	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF38_3499	COG0456	acetyltransferase
BF38_350	COG0372	Belongs to the citrate synthase family
BF38_3500	COG3829	transcription factor binding
BF38_3501	COG1509	lysine 2,3-aminomutase activity
BF38_3509	COG4326	sporulation control protein
BF38_3510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF38_3511	COG0671	phosphoesterase, PA-phosphatase related
BF38_3512	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF38_352	COG0628	permease
BF38_3527	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF38_353	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF38_3535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF38_3535	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF38_3536	COG2814	Major facilitator Superfamily
BF38_3537	COG4841	protein insertion into membrane
BF38_3538	COG0372	Belongs to the citrate synthase family
BF38_3539	COG2079	MmgE PrpD family protein
BF38_3540	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF38_3541	COG1960	acyl-CoA dehydrogenase activity
BF38_3542	COG2084	Dehydrogenase
BF38_3543	COG1012	belongs to the aldehyde dehydrogenase family
BF38_3544	COG1280	lysine exporter protein (LysE YggA)
BF38_3545	COG1024	Enoyl-CoA hydratase
BF38_3548	COG0420	3'-5' exonuclease activity
BF38_3549	COG0419	ATPase involved in DNA repair
BF38_3552	COG2223	nitrite transmembrane transporter activity
BF38_3553	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_3554	COG1169	isochorismate synthase
BF38_3555	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF38_3556	COG1535	isochorismatase
BF38_3556	COG3433	isochorismatase activity
BF38_3557	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF38_3558	COG3251	PFAM MbtH domain protein
BF38_3559	COG2814	Major facilitator Superfamily
BF38_3562	COG0776	regulation of translation
BF38_3564	COG2318	DinB family
BF38_3566	COG1115	amino acid carrier protein
BF38_3569	COG2329	Antibiotic biosynthesis monooxygenase
BF38_3570	COG1187	pseudouridine synthase activity
BF38_3571	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF38_3572	COG1136	(ABC) transporter
BF38_3574	COG0596	Alpha beta hydrolase
BF38_3578	COG2226	methyltransferase
BF38_358	COG1725	Transcriptional regulator
BF38_3585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_359	COG0281	malic enzyme
BF38_3591	COG1247	-acetyltransferase
BF38_3599	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_360	COG0587	DNA-directed DNA polymerase activity
BF38_3601	COG1278	Cold shock
BF38_3604	COG0010	Belongs to the arginase family
BF38_3605	COG0561	phosphatase activity
BF38_3612	COG0583	DNA-binding transcription factor activity
BF38_3613	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF38_3616	COG0583	DNA-binding transcription factor activity
BF38_3617	COG2258	MOSC domain
BF38_3620	COG1132	(ABC) transporter
BF38_3621	COG1132	(ABC) transporter
BF38_3625	COG1396	sequence-specific DNA binding
BF38_363	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF38_3632	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF38_3635	COG1595	DNA-templated transcription, initiation
BF38_3641	COG1649	PFAM Uncharacterised BCR, COG1649
BF38_3646	COG2971	BadF BadG BcrA BcrD
BF38_3648	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF38_3653	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_3658	COG1309	transcriptional regulator
BF38_367	COG4109	DRTGG domain
BF38_3670	COG0582	viral genome integration into host DNA
BF38_3674	COG1136	(ABC) transporter
BF38_3674	COG0577	efflux transmembrane transporter activity
BF38_3675	COG3615	Tellurite resistance protein tehB
BF38_3675	COG0500	methyltransferase
BF38_3677	COG2226	methyltransferase
BF38_3678	COG3961	Belongs to the TPP enzyme family
BF38_3679	COG1846	Transcriptional regulator
BF38_3685	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF38_3689	COG1595	DNA-templated transcription, initiation
BF38_3691	COG0768	penicillin binding
BF38_3693	COG2367	Beta-lactamase
BF38_3694	COG0671	phosphoesterase, PA-phosphatase related
BF38_3695	COG1609	Transcriptional regulator
BF38_3696	COG2814	Major facilitator Superfamily
BF38_3697	COG0673	inositol 2-dehydrogenase activity
BF38_37	COG0735	belongs to the Fur family
BF38_370	COG0006	proline dipeptidase activity
BF38_3703	COG3718	enzyme involved in inositol metabolism
BF38_3706	COG0737	Belongs to the 5'-nucleotidase family
BF38_3708	COG0457	Tetratricopeptide repeat
BF38_3709	COG1476	TRANSCRIPTIONal
BF38_3712	COG1876	peptidase activity
BF38_3716	COG1309	transcriptional regulator
BF38_3720	COG1252	NADH dehydrogenase
BF38_3721	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF38_3724	COG1131	(ABC) transporter
BF38_3726	COG1309	transcriptional regulator
BF38_3729	COG1960	acyl-CoA dehydrogenase activity
BF38_3730	COG0439	Biotin carboxylase
BF38_3731	COG0511	ligase activity, forming carbon-carbon bonds
BF38_3732	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF38_3733	COG1024	Enoyl-CoA hydratase
BF38_3734	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF38_3735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF38_3737	COG1247	-acetyltransferase
BF38_3738	COG0572	uridine kinase
BF38_3740	COG2318	DinB family
BF38_3741	COG1686	Belongs to the peptidase S11 family
BF38_3746	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF38_3750	COG3227	Zinc metalloprotease (Elastase)
BF38_3757	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF38_3759	COG2814	Major facilitator Superfamily
BF38_3763	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF38_3767	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_3770	COG1063	alcohol dehydrogenase
BF38_3774	COG3386	PFAM SMP-30 Gluconolaconase
BF38_3776	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BF38_3777	COG3773	Cell wall hydrolase
BF38_3779	COG0745	RESPONSE REGULATOR receiver
BF38_3780	COG2205	protein histidine kinase activity
BF38_3785	COG1136	(ABC) transporter
BF38_3786	COG0577	efflux transmembrane transporter activity
BF38_379	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_3790	COG0460	homoserine dehydrogenase
BF38_3791	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_3793	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF38_38	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF38_380	COG0662	Cupin 2, conserved barrel domain protein
BF38_3807	COG2124	cytochrome p450
BF38_3814	COG0561	phosphatase activity
BF38_3815	COG5002	protein histidine kinase activity
BF38_3817	COG1819	glycosyl
BF38_3818	COG1794	racemase activity, acting on amino acids and derivatives
BF38_382	COG1476	TRANSCRIPTIONal
BF38_3823	COG2205	protein histidine kinase activity
BF38_3826	COG0604	alcohol dehydrogenase
BF38_3829	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF38_3835	COG0693	protein deglycase activity
BF38_3841	COG2814	Major facilitator Superfamily
BF38_3845	COG0584	glycerophosphoryl diester phosphodiesterase
BF38_3848	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_3849	COG0697	spore germination
BF38_385	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_3857	COG2223	nitrite transmembrane transporter activity
BF38_386	COG0589	response to stress
BF38_3861	COG0592	DNA-directed DNA polymerase activity
BF38_3862	COG1051	belongs to the nudix hydrolase family
BF38_3870	COG3878	Protein conserved in bacteria
BF38_3874	COG4667	esterase of the alpha-beta hydrolase superfamily
BF38_3879	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF38_3882	COG0322	excinuclease ABC activity
BF38_3890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF38_3898	COG1073	alpha beta
BF38_39	COG1121	(ABC) transporter
BF38_3900	COG0076	glutamate decarboxylase activity
BF38_3903	COG1523	belongs to the glycosyl hydrolase 13 family
BF38_3904	COG3227	Zinc metalloprotease (Elastase)
BF38_3908	COG0201	protein transport
BF38_3910	COG0697	spore germination
BF38_3911	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_3919	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_3922	COG2959	enzyme of heme biosynthesis
BF38_3923	COG3409	Peptidoglycan-binding domain 1 protein
BF38_3923	COG3773	Cell wall hydrolase
BF38_3929	COG1309	transcriptional regulator
BF38_3935	COG3284	Transcriptional regulator
BF38_3939	COG1349	DNA-binding transcription factor activity
BF38_3943	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF38_3944	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF38_3945	COG0022	dehydrogenase e1 component
BF38_3946	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF38_3948	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_3949	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF38_3949	COG0456	acetyltransferase
BF38_395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_3950	COG0572	uridine kinase
BF38_3956	COG4176	ABC-type proline glycine betaine transport system permease component
BF38_3957	COG4175	Glycine betaine
BF38_3957	COG0517	IMP dehydrogenase activity
BF38_3959	COG0740	serine-type endopeptidase activity
BF38_3963	COG2153	protein acetylation
BF38_3964	COG3397	chitin binding
BF38_3967	COG2205	protein histidine kinase activity
BF38_3968	COG2226	methyltransferase
BF38_3972	COG2333	competence protein COMEC
BF38_3972	COG0658	competence protein
BF38_3982	COG3973	AAA domain
BF38_3985	COG2105	PFAM AIG2 family protein
BF38_3986	COG0514	ATP-dependent DNA helicase (RecQ)
BF38_3990	COG4637	Psort location Cytoplasmic, score
BF38_3995	COG3397	chitin binding
BF38_3997	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF38_3998	COG1115	amino acid carrier protein
BF38_3999	COG1012	belongs to the aldehyde dehydrogenase family
BF38_40	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_400	COG0827	DNA restriction-modification system
BF38_4000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF38_4002	COG3938	Belongs to the proline racemase family
BF38_4003	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF38_401	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF38_4011	COG0586	Pfam SNARE associated Golgi protein
BF38_4014	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF38_4015	COG0519	Catalyzes the synthesis of GMP from XMP
BF38_4016	COG4166	transmembrane transport
BF38_4018	COG4948	Mandelate Racemase Muconate Lactonizing
BF38_402	COG3874	Sporulation protein YtfJ
BF38_4025	COG2936	dipeptidyl-peptidase activity
BF38_4026	COG5002	protein histidine kinase activity
BF38_4027	COG0745	RESPONSE REGULATOR receiver
BF38_4034	COG1164	Oligoendopeptidase f
BF38_4036	COG1307	EDD domain protein, DegV family
BF38_404	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF38_4040	COG2814	Major facilitator Superfamily
BF38_4042	COG1664	Polymer-forming cytoskeletal
BF38_4043	COG0789	Transcriptional regulator
BF38_4044	COG4533	DNA binding
BF38_4045	COG0477	Major facilitator Superfamily
BF38_4045	COG2814	Major facilitator Superfamily
BF38_4049	COG2261	transglycosylase associated protein
BF38_405	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF38_4052	COG2226	methyltransferase
BF38_4059	COG0436	Aminotransferase
BF38_4060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF38_4061	COG5146	pantothenate kinase activity
BF38_4062	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BF38_4065	COG1131	(ABC) transporter
BF38_407	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF38_4074	COG0628	permease
BF38_4076	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF38_4077	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF38_4078	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF38_4079	COG1116	anion transmembrane transporter activity
BF38_4087	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF38_4092	COG0697	spore germination
BF38_4093	COG2318	DinB family
BF38_4097	COG4912	Dna alkylation repair
BF38_410	COG1104	cysteine desulfurase activity
BF38_4101	COG0861	Integral membrane protein TerC family
BF38_4102	COG1368	sulfuric ester hydrolase activity
BF38_4103	COG0488	(ABC) transporter
BF38_4105	COG1033	growth of symbiont in host cell
BF38_4105	COG2409	Drug exporters of the RND superfamily
BF38_4106	COG1309	transcriptional regulator
BF38_4109	COG0287	Prephenate dehydrogenase
BF38_4110	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF38_4112	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF38_4112	COG1605	Chorismate mutase
BF38_4119	COG3584	3D domain protein
BF38_4119	COG1388	LysM domain
BF38_412	COG0583	DNA-binding transcription factor activity
BF38_4121	COG2610	gluconate transmembrane transporter activity
BF38_4122	COG1024	Enoyl-CoA hydratase
BF38_4124	COG3290	protein histidine kinase activity
BF38_4124	COG3829	transcription factor binding
BF38_4128	COG1879	ABC-type sugar transport system periplasmic component
BF38_413	COG0697	spore germination
BF38_4130	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF38_4132	COG2390	Transcriptional regulator
BF38_4133	COG1070	Carbohydrate kinase
BF38_4139	COG2329	Antibiotic biosynthesis monooxygenase
BF38_414	COG1309	transcriptional regulator
BF38_4143	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF38_4145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF38_4146	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF38_4149	COG4187	Peptidase family M20/M25/M40
BF38_415	COG1956	GAF domain-containing protein
BF38_4150	COG1414	Transcriptional regulator
BF38_4151	COG0833	amino acid
BF38_4152	COG1690	Belongs to the RtcB family
BF38_4153	COG3239	Fatty acid desaturase
BF38_4154	COG1785	Belongs to the alkaline phosphatase family
BF38_4156	COG3655	Transcriptional regulator
BF38_4159	COG4377	Putative membrane peptidase family (DUF2324)
BF38_416	COG0626	cystathionine gamma-synthase activity
BF38_4161	COG3279	Response regulator of the LytR AlgR family
BF38_4163	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_4164	COG0346	lactoylglutathione lyase activity
BF38_4169	COG0714	Associated with various cellular activities
BF38_4174	COG0463	Glycosyl transferase, family 2
BF38_4178	COG0463	Glycosyl transferase, family 2
BF38_4180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF38_4181	COG0753	catalase activity
BF38_4183	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF38_4188	COG0714	Associated with various cellular activities
BF38_4190	COG0778	Nitroreductase
BF38_4191	COG1846	Transcriptional regulator
BF38_4195	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF38_4197	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF38_4199	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF38_4200	COG0183	Belongs to the thiolase family
BF38_4201	COG1024	Enoyl-CoA hydratase
BF38_4202	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF38_4203	COG2723	6-phospho-beta-galactosidase activity
BF38_4204	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF38_4205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF38_4206	COG0588	phosphoglycerate mutase activity
BF38_4208	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF38_4210	COG2508	Transcriptional regulator
BF38_4211	COG2814	Major facilitator Superfamily
BF38_4212	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF38_4218	COG1725	Transcriptional regulator
BF38_422	COG1595	DNA-templated transcription, initiation
BF38_4220	COG1136	(ABC) transporter
BF38_4225	COG2207	Transcriptional regulator
BF38_4226	COG0456	acetyltransferase
BF38_4230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_4239	COG0730	response to heat
BF38_424	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF38_4241	COG0833	amino acid
BF38_4243	COG4335	DNA alkylation repair
BF38_425	COG0454	-acetyltransferase
BF38_4256	COG1984	allophanate hydrolase subunit 2
BF38_4257	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF38_4258	COG1414	Transcriptional regulator
BF38_426	COG0517	IMP dehydrogenase activity
BF38_4261	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF38_4262	COG0640	Transcriptional regulator
BF38_4264	COG1960	acyl-CoA dehydrogenase activity
BF38_427	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF38_4271	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF38_4274	COG3848	Pyruvate phosphate dikinase
BF38_4274	COG0574	Belongs to the PEP-utilizing enzyme family
BF38_4276	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_4279	COG5577	PFAM Coat F domain
BF38_428	COG2267	carboxylic ester hydrolase activity
BF38_4281	COG3403	YqcI/YcgG family
BF38_4282	COG1280	lysine exporter protein (LysE YggA)
BF38_4283	COG1113	amino acid transport
BF38_4289	COG1063	alcohol dehydrogenase
BF38_4291	COG1027	Aspartate ammonia-lyase
BF38_4292	COG0252	asparaginase activity
BF38_4293	COG1396	sequence-specific DNA binding
BF38_4298	COG5002	protein histidine kinase activity
BF38_430	COG0745	RESPONSE REGULATOR receiver
BF38_4303	COG2207	Transcriptional regulator
BF38_4304	COG0322	excinuclease ABC activity
BF38_4305	COG0531	amino acid
BF38_4306	COG1114	Component of the transport system for branched-chain amino acids
BF38_4307	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF38_4311	COG0531	amino acid
BF38_4312	COG0697	spore germination
BF38_4313	COG0784	Response regulator, receiver
BF38_4314	COG4191	Histidine kinase
BF38_4315	COG2066	Belongs to the glutaminase family
BF38_4316	COG1115	amino acid carrier protein
BF38_4318	COG0737	Belongs to the 5'-nucleotidase family
BF38_4319	COG0753	catalase activity
BF38_432	COG0666	response to abiotic stimulus
BF38_4320	COG2267	carboxylic ester hydrolase activity
BF38_4321	COG1335	isochorismatase
BF38_4322	COG1335	isochorismatase
BF38_4325	COG0583	DNA-binding transcription factor activity
BF38_4326	COG1846	Transcriptional regulator
BF38_4327	COG0598	Magnesium transport protein CorA
BF38_4334	COG0415	Belongs to the DNA photolyase family
BF38_4335	COG0288	reversible hydration of carbon dioxide
BF38_4337	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF38_4338	COG5609	conserved protein (DUF2294)
BF38_4340	COG1575	Belongs to the MenA family. Type 1 subfamily
BF38_4341	COG2267	carboxylic ester hydrolase activity
BF38_4342	COG4641	Protein conserved in bacteria
BF38_4343	COG1136	(ABC) transporter
BF38_4348	COG0798	PFAM Bile acid sodium symporter
BF38_4349	COG0346	lactoylglutathione lyase activity
BF38_4350	COG0640	Transcriptional regulator
BF38_4354	COG5002	protein histidine kinase activity
BF38_4355	COG0745	RESPONSE REGULATOR receiver
BF38_4356	COG0456	acetyltransferase
BF38_4357	COG3320	Male sterility
BF38_4357	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF38_4359	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_4360	COG1522	sequence-specific DNA binding
BF38_4363	COG0346	lactoylglutathione lyase activity
BF38_4366	COG2169	Transcriptional regulator
BF38_4373	COG2814	Major facilitator Superfamily
BF38_4378	COG0745	RESPONSE REGULATOR receiver
BF38_4379	COG5002	protein histidine kinase activity
BF38_4379	COG3850	Histidine kinase
BF38_4384	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF38_4389	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_439	COG1609	Transcriptional regulator
BF38_4390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF38_4392	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF38_4395	COG2309	aminopeptidase activity
BF38_4397	COG0789	Transcriptional regulator
BF38_440	COG4851	CamS sex pheromone cAM373 precursor
BF38_4402	COG1136	(ABC) transporter
BF38_4403	COG0577	efflux transmembrane transporter activity
BF38_4406	COG3850	Histidine kinase
BF38_4406	COG5002	protein histidine kinase activity
BF38_4408	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_4409	COG2271	Major facilitator Superfamily
BF38_441	COG3118	belongs to the thioredoxin family
BF38_4410	COG1556	Lactate utilization protein
BF38_4411	COG1139	Iron-sulfur cluster binding protein
BF38_4413	COG0583	DNA-binding transcription factor activity
BF38_4415	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF38_4419	COG0738	Major facilitator superfamily
BF38_4420	COG0673	inositol 2-dehydrogenase activity
BF38_4421	COG0561	phosphatase activity
BF38_4422	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF38_4423	COG1609	Transcriptional regulator
BF38_4424	COG0457	Tetratricopeptide repeat
BF38_4428	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF38_443	COG2309	aminopeptidase activity
BF38_4432	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_4434	COG0814	amino acid
BF38_4435	COG1760	l-serine dehydratase
BF38_4436	COG1760	l-serine dehydratase
BF38_4437	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF38_4438	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF38_4440	COG1335	isochorismatase
BF38_4441	COG1522	sequence-specific DNA binding
BF38_4442	COG0531	amino acid
BF38_4445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF38_4449	COG0662	Cupin 2, conserved barrel domain protein
BF38_4450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_4450	COG2207	Transcriptional regulator
BF38_4454	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF38_4454	COG3409	Peptidoglycan-binding domain 1 protein
BF38_4462	COG0477	Major facilitator Superfamily
BF38_4464	COG1846	Transcriptional regulator
BF38_4465	COG2814	Major facilitator Superfamily
BF38_4468	COG2076	Multidrug Resistance protein
BF38_4469	COG1309	transcriptional regulator
BF38_447	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_4471	COG2031	fatty acid transporter
BF38_4473	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF38_448	COG0697	spore germination
BF38_4480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF38_4484	COG1288	antiporter activity
BF38_4487	COG2814	Major facilitator Superfamily
BF38_4488	COG1309	transcriptional regulator
BF38_449	COG0789	Transcriptional regulator
BF38_4490	COG3620	sequence-specific DNA binding
BF38_4491	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF38_4495	COG1733	regulation of RNA biosynthetic process
BF38_4496	COG0778	Nitroreductase
BF38_4500	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_4502	COG1131	(ABC) transporter
BF38_4507	COG1011	Hydrolase
BF38_4514	COG0346	lactoylglutathione lyase activity
BF38_4515	COG1940	carbohydrate kinase activity
BF38_4516	COG0738	Major facilitator superfamily
BF38_4517	COG0110	maltose O-acetyltransferase activity
BF38_4519	COG1136	(ABC) transporter
BF38_4519	COG0577	efflux transmembrane transporter activity
BF38_452	COG1674	ftsk spoiiie
BF38_4521	COG0180	Tryptophanyl-tRNA synthetase
BF38_4523	COG0628	permease
BF38_4527	COG2226	methyltransferase
BF38_4529	COG0477	Major facilitator Superfamily
BF38_4535	COG1253	flavin adenine dinucleotide binding
BF38_4536	COG0789	Transcriptional regulator
BF38_4537	COG0697	spore germination
BF38_4538	COG1357	PFAM Pentapeptide repeats (8 copies)
BF38_4539	COG3813	Protein conserved in bacteria
BF38_454	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF38_4540	COG2706	6-phosphogluconolactonase activity
BF38_4541	COG1070	Carbohydrate kinase
BF38_4543	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF38_4544	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF38_4546	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF38_4548	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF38_4551	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_4556	COG0656	L-ascorbic acid biosynthetic process
BF38_4559	COG0814	amino acid
BF38_456	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF38_4564	COG1393	Belongs to the ArsC family
BF38_4565	COG1733	regulation of RNA biosynthetic process
BF38_4566	COG2188	Transcriptional regulator
BF38_4567	COG0673	inositol 2-dehydrogenase activity
BF38_4568	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF38_4569	COG1733	regulation of RNA biosynthetic process
BF38_457	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF38_4570	COG1733	regulation of RNA biosynthetic process
BF38_4574	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_4578	COG0384	phenazine biosynthesis protein PhzF
BF38_458	COG1363	Peptidase, m42
BF38_4581	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_4584	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_4585	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF38_4586	COG1733	regulation of RNA biosynthetic process
BF38_4588	COG0726	polysaccharide deacetylase
BF38_4590	COG1191	sigma factor activity
BF38_4593	COG1309	transcriptional regulator
BF38_4597	COG3152	Membrane
BF38_46	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF38_460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_4602	COG1151	hydroxylamine reductase activity
BF38_4605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_4613	COG2072	flavoprotein involved in K transport
BF38_4620	COG0604	alcohol dehydrogenase
BF38_4621	COG1113	amino acid transport
BF38_4622	COG2814	Major facilitator Superfamily
BF38_4628	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF38_4629	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF38_463	COG0510	thiamine kinase activity
BF38_4632	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_4633	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_4634	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_4635	COG3739	integral membrane protein
BF38_4636	COG0384	phenazine biosynthesis protein PhzF
BF38_464	COG1523	belongs to the glycosyl hydrolase 13 family
BF38_4642	COG0583	DNA-binding transcription factor activity
BF38_4646	COG1193	negative regulation of DNA recombination
BF38_4649	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF38_4650	COG1164	Oligoendopeptidase f
BF38_4651	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF38_4657	COG0584	glycerophosphoryl diester phosphodiesterase
BF38_466	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF38_4661	COG0640	Transcriptional regulator
BF38_4662	COG0604	alcohol dehydrogenase
BF38_467	COG1349	DNA-binding transcription factor activity
BF38_4671	COG2808	Putative FMN-binding domain
BF38_4672	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF38_4674	COG0385	Bile acid
BF38_4675	COG0277	FAD linked oxidase domain protein
BF38_468	COG1187	pseudouridine synthase activity
BF38_4681	COG1216	Glycosyl transferase, family 2
BF38_4682	COG1024	Enoyl-CoA hydratase
BF38_4684	COG1285	pathogenesis
BF38_4686	COG2514	catechol 2,3-dioxygenase activity
BF38_4687	COG2720	vancomycin resistance protein
BF38_469	COG2244	polysaccharide biosynthetic process
BF38_4693	COG1278	Cold shock
BF38_4695	COG0716	FMN binding
BF38_47	COG2384	SAM-dependent methyltransferase
BF38_470	COG2081	HI0933 family
BF38_4702	COG2801	Transposase and inactivated derivatives
BF38_4706	COG0739	heme binding
BF38_4707	COG0741	lytic transglycosylase activity
BF38_4708	COG3409	Peptidoglycan-binding domain 1 protein
BF38_4708	COG3757	hydrolase, family 25
BF38_4709	COG0739	heme binding
BF38_471	COG2814	Major facilitator Superfamily
BF38_4721	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_4723	COG0165	Argininosuccinate lyase
BF38_4726	COG4145	pantothenate transmembrane transporter activity
BF38_4728	COG1012	belongs to the aldehyde dehydrogenase family
BF38_4729	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_473	COG3832	glyoxalase III activity
BF38_4731	COG1657	PFAM Prenyltransferase squalene oxidase
BF38_4732	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF38_4733	COG2962	Rard protein
BF38_4734	COG3326	Membrane
BF38_4737	COG0489	protein tyrosine kinase activity
BF38_4739	COG0314	molybdopterin synthase activity
BF38_4740	COG0303	'Molybdopterin
BF38_4741	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF38_4742	COG2116	formate transmembrane transporter activity
BF38_4744	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF38_4745	COG5609	conserved protein (DUF2294)
BF38_4746	COG2427	Protein of unknown function (DUF1641)
BF38_4747	COG3383	formate dehydrogenase (NAD+) activity
BF38_4749	COG0697	spore germination
BF38_4757	COG2226	methyltransferase
BF38_4758	COG4166	transmembrane transport
BF38_4761	COG2801	Transposase and inactivated derivatives
BF38_4762	COG4166	transmembrane transport
BF38_4763	COG4166	transmembrane transport
BF38_4764	COG1301	dicarboxylic acid transport
BF38_4765	COG1316	TRANSCRIPTIONal
BF38_4767	COG1595	DNA-templated transcription, initiation
BF38_477	COG1329	Transcriptional regulator
BF38_4771	COG1131	(ABC) transporter
BF38_4773	COG0673	inositol 2-dehydrogenase activity
BF38_4774	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF38_4775	COG0187	DNA topoisomerase II activity
BF38_4776	COG1832	CoA-binding protein
BF38_4777	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF38_4778	COG0745	RESPONSE REGULATOR receiver
BF38_4782	COG4841	protein insertion into membrane
BF38_4783	COG0824	Thioesterase
BF38_4788	COG2176	DNA-directed DNA polymerase activity
BF38_4789	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF38_4791	COG2274	protein secretion by the type I secretion system
BF38_4792	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF38_4794	COG0726	polysaccharide deacetylase
BF38_4798	COG2211	Major facilitator Superfamily
BF38_48	COG2010	Cytochrome c
BF38_4800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF38_4803	COG0183	Belongs to the thiolase family
BF38_4804	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_4805	COG1268	BioY protein
BF38_4806	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_4815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_4817	COG5002	protein histidine kinase activity
BF38_4818	COG0400	carboxylic ester hydrolase activity
BF38_4819	COG0346	lactoylglutathione lyase activity
BF38_482	COG0314	molybdopterin synthase activity
BF38_4820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF38_4821	COG0069	glutamate synthase activity
BF38_4822	COG1902	pentaerythritol trinitrate reductase activity
BF38_4823	COG1329	Transcriptional regulator
BF38_4824	COG0010	Belongs to the arginase family
BF38_483	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF38_4830	COG2226	methyltransferase
BF38_4836	COG4846	Membrane protein involved in cytochrome C biogenesis
BF38_4837	COG0785	Cytochrome C biogenesis protein
BF38_484	COG0303	'Molybdopterin
BF38_4841	COG1131	(ABC) transporter
BF38_4843	COG0583	DNA-binding transcription factor activity
BF38_4845	COG1346	cytolysis
BF38_4848	COG0730	response to heat
BF38_4850	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF38_4850	COG3409	Peptidoglycan-binding domain 1 protein
BF38_4853	COG1132	(ABC) transporter
BF38_4854	COG1132	(ABC) transporter
BF38_486	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF38_4860	COG3639	organic phosphonate transmembrane transporter activity
BF38_4861	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF38_4862	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF38_4863	COG0737	Belongs to the 5'-nucleotidase family
BF38_4865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF38_4869	COG1695	Transcriptional regulator
BF38_487	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF38_4872	COG5444	nuclease activity
BF38_4875	COG0174	glutamine synthetase
BF38_4876	COG0789	Transcriptional regulator
BF38_4877	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF38_4878	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF38_4879	COG2860	membrane
BF38_4881	COG0464	growth
BF38_4887	COG3584	3D domain protein
BF38_4887	COG1388	LysM domain
BF38_4888	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF38_4888	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF38_4888	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF38_4889	COG1105	Belongs to the carbohydrate kinase PfkB family
BF38_4890	COG1349	DNA-binding transcription factor activity
BF38_4891	COG1979	alcohol dehydrogenase
BF38_4892	COG2322	membrane
BF38_4895	COG1113	amino acid transport
BF38_4898	COG1408	metallophosphoesterase
BF38_4899	COG2116	formate transmembrane transporter activity
BF38_49	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF38_4901	COG2217	Heavy metal translocating P-type atpase
BF38_4902	COG2608	mercury ion transmembrane transporter activity
BF38_4903	COG1937	Protein conserved in bacteria
BF38_4905	COG2819	hydrolase of the alpha beta superfamily
BF38_4906	COG1120	ATPase activity
BF38_4907	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_4908	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF38_4909	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF38_491	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF38_4910	COG0708	Exodeoxyribonuclease III
BF38_4911	COG2169	Transcriptional regulator
BF38_4912	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF38_4913	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF38_4915	COG2364	Membrane
BF38_4918	COG2267	carboxylic ester hydrolase activity
BF38_4919	COG0346	lactoylglutathione lyase activity
BF38_4920	COG5001	Diguanylate cyclase
BF38_4920	COG3300	MHYT domain
BF38_4923	COG1346	cytolysis
BF38_4924	COG1380	Effector of murein hydrolase LrgA
BF38_4925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF38_4928	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF38_493	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF38_4931	COG1404	Belongs to the peptidase S8 family
BF38_4932	COG3773	Cell wall hydrolase
BF38_4933	COG0562	UDP-galactopyranose mutase
BF38_4934	COG1368	sulfuric ester hydrolase activity
BF38_4935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF38_4937	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF38_4941	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF38_4943	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF38_4944	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF38_4944	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF38_4946	COG2359	stage V sporulation protein S
BF38_4947	COG1692	metallophosphoesterase
BF38_4952	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF38_4953	COG1426	Protein conserved in bacteria
BF38_4956	COG0300	oxidoreductase activity
BF38_4957	COG0612	Peptidase, M16
BF38_4958	COG0612	Peptidase, M16
BF38_4963	COG2188	Transcriptional regulator
BF38_4964	COG1674	ftsk spoiiie
BF38_4966	COG0740	serine-type endopeptidase activity
BF38_4967	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF38_4969	COG0527	aspartate kinase activity
BF38_4970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF38_4971	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF38_4972	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF38_4973	COG1873	PFAM PRC-barrel domain
BF38_4974	COG0612	Peptidase, M16
BF38_4975	COG0726	polysaccharide deacetylase
BF38_4978	COG0196	riboflavin kinase activity
BF38_4979	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF38_4981	COG1550	Protein conserved in bacteria
BF38_4983	COG1358	cellular component organization or biogenesis
BF38_4984	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF38_4985	COG0195	Participates in both transcription termination and antitermination
BF38_4989	COG0750	zinc metalloprotease
BF38_4990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF38_4991	COG4589	Belongs to the CDS family
BF38_4994	COG0528	UMP kinase activity
BF38_50	COG0358	DNA primase activity
BF38_5000	COG4974	Belongs to the 'phage' integrase family
BF38_5002	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF38_5003	COG0758	DNA mediated transformation
BF38_5004	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF38_501	COG2814	Major facilitator Superfamily
BF38_5012	COG1837	Belongs to the UPF0109 family
BF38_5014	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF38_5016	COG0552	protein localization to endoplasmic reticulum
BF38_5017	COG1196	nuclear chromosome segregation
BF38_502	COG0475	glutathione-regulated potassium exporter activity
BF38_5020	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5021	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF38_5024	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF38_5025	COG1461	Dihydroxyacetone kinase
BF38_5026	COG1302	Protein conserved in bacteria
BF38_5028	COG1564	THIamine pyrophosphokinase
BF38_5029	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF38_503	COG0490	domain, Protein
BF38_5030	COG1162	GTPase activity
BF38_5031	COG2815	serine threonine protein kinase
BF38_5031	COG0515	serine threonine protein kinase
BF38_5032	COG0631	protein serine/threonine phosphatase activity
BF38_5034	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF38_5034	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF38_5036	COG0242	peptide deformylase activity
BF38_5037	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF38_5038	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF38_504	COG0582	viral genome integration into host DNA
BF38_5040	COG0194	GDP metabolic process
BF38_5042	COG1561	YicC-like family, N-terminal region
BF38_5043	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF38_5045	COG0006	proline dipeptidase activity
BF38_5049	COG3069	C4-dicarboxylate transmembrane transporter activity
BF38_5057	COG0505	Belongs to the CarA family
BF38_506	COG1136	(ABC) transporter
BF38_5062	COG0564	pseudouridine synthase activity
BF38_5066	COG3599	regulation of cell shape
BF38_5067	COG2302	S4 RNA-binding domain
BF38_5068	COG0762	integral membrane protein
BF38_5070	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF38_5072	COG1873	PFAM PRC-barrel domain
BF38_5073	COG1191	sigma factor activity
BF38_5074	COG1191	sigma factor activity
BF38_5076	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF38_5077	COG0849	cell division
BF38_5078	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF38_5079	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF38_5080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF38_5081	COG0772	Belongs to the SEDS family
BF38_5084	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF38_5085	COG0768	penicillin binding
BF38_5087	COG4839	cell division protein FtsL
BF38_5090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF38_5094	COG1399	metal-binding, possibly nucleic acid-binding protein
BF38_5096	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF38_5097	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF38_5099	COG3314	Sporulation integral membrane protein YlbJ
BF38_510	COG1242	4 iron, 4 sulfur cluster binding
BF38_5100	COG0742	ribosomal rna small subunit methyltransferase
BF38_5103	COG3679	Belongs to the UPF0342 family
BF38_5104	COG0406	alpha-ribazole phosphatase activity
BF38_5107	COG2340	Cysteine-rich secretory protein family
BF38_511	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF38_5110	COG3336	cytochrome c oxidase
BF38_5117	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF38_5118	COG0772	Belongs to the SEDS family
BF38_512	COG1131	(ABC) transporter
BF38_5120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF38_5121	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF38_5123	COG4896	Protein conserved in bacteria
BF38_5128	COG0483	inositol monophosphate 1-phosphatase activity
BF38_5132	COG1982	Orn Lys Arg decarboxylase major
BF38_514	COG1794	racemase activity, acting on amino acids and derivatives
BF38_5142	COG0022	dehydrogenase e1 component
BF38_5143	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF38_5145	COG0242	peptide deformylase activity
BF38_5146	COG0561	phosphatase activity
BF38_5148	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF38_5149	COG0569	domain protein
BF38_5153	COG0583	DNA-binding transcription factor activity
BF38_5154	COG0517	IMP dehydrogenase activity
BF38_5156	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF38_5158	COG4703	Protein of unknown function (DUF1797)
BF38_5161	COG2200	EAL domain
BF38_5162	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5163	COG1408	metallophosphoesterase
BF38_5165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF38_5172	COG2814	Major facilitator Superfamily
BF38_5176	COG3209	COG3209 Rhs family protein
BF38_5178	COG2205	protein histidine kinase activity
BF38_518	COG2267	carboxylic ester hydrolase activity
BF38_5180	COG0436	Aminotransferase
BF38_5181	COG1609	Transcriptional regulator
BF38_5182	COG3833	ABC-type maltose transport systems, permease component
BF38_5183	COG1175	transmembrane transport
BF38_5184	COG2182	Extracellular solute-binding protein
BF38_5186	COG0366	Alpha amylase catalytic
BF38_5187	COG3842	ATPase activity
BF38_519	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF38_5195	COG0183	Belongs to the thiolase family
BF38_52	COG0517	IMP dehydrogenase activity
BF38_520	COG0671	phosphoesterase, PA-phosphatase related
BF38_5202	COG1695	Transcriptional regulator
BF38_5203	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5207	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF38_5208	COG0436	Aminotransferase
BF38_521	COG0438	transferase activity, transferring glycosyl groups
BF38_5215	COG2084	Dehydrogenase
BF38_5216	COG3706	GGDEF domain
BF38_5217	COG0778	Nitroreductase
BF38_5222	COG2190	(PTS) system
BF38_5222	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF38_5222	COG1263	PTS System
BF38_5223	COG3711	transcriptional antiterminator
BF38_5227	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF38_523	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF38_5232	COG1547	Domain of unknown function (DUF309)
BF38_5233	COG0456	acetyltransferase
BF38_5234	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF38_5235	COG4086	secreted protein
BF38_5236	COG0561	phosphatase activity
BF38_5237	COG0697	spore germination
BF38_5240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF38_5245	COG0733	neurotransmitter:sodium symporter activity
BF38_5249	COG1686	Belongs to the peptidase S11 family
BF38_5250	COG1725	Transcriptional regulator
BF38_5251	COG1131	(ABC) transporter
BF38_5255	COG1846	Transcriptional regulator
BF38_5258	COG0598	Magnesium transport protein CorA
BF38_5263	COG4974	Belongs to the 'phage' integrase family
BF38_5265	COG0735	belongs to the Fur family
BF38_5266	COG1300	Membrane
BF38_5270	COG0667	Aldo Keto reductase
BF38_5271	COG0656	L-ascorbic acid biosynthetic process
BF38_5272	COG0456	acetyltransferase
BF38_5272	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF38_5274	COG4085	toxin activity
BF38_5274	COG1525	nuclease
BF38_5274	COG0737	Belongs to the 5'-nucleotidase family
BF38_5276	COG0596	Alpha beta hydrolase
BF38_5277	COG2056	Na+-H+ antiporter family
BF38_5278	COG1609	Transcriptional regulator
BF38_5279	COG0456	acetyltransferase
BF38_5280	COG1073	alpha beta
BF38_5283	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF38_5283	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF38_5284	COG0307	riboflavin synthase, alpha
BF38_5288	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF38_5289	COG4106	trans-aconitate 2-methyltransferase activity
BF38_5290	COG2226	methyltransferase
BF38_5290	COG1073	alpha beta
BF38_5291	COG0156	8-amino-7-oxononanoate synthase activity
BF38_5293	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF38_5296	COG0737	Belongs to the 5'-nucleotidase family
BF38_5298	COG1522	sequence-specific DNA binding
BF38_5302	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF38_5304	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF38_5307	COG0300	oxidoreductase activity
BF38_5308	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_5309	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF38_5310	COG1760	l-serine dehydratase
BF38_5311	COG1760	l-serine dehydratase
BF38_5314	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF38_5316	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF38_5317	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_5319	COG1376	ErfK ybiS ycfS ynhG family protein
BF38_5320	COG4129	membrane
BF38_5321	COG1126	abc transporter atp-binding protein
BF38_5322	COG0765	amino acid transport
BF38_5323	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF38_5326	COG2816	NAD+ diphosphatase activity
BF38_5327	COG0772	Belongs to the SEDS family
BF38_5328	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF38_5329	COG0022	dehydrogenase e1 component
BF38_5330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF38_5331	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF38_5333	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF38_5334	COG0280	phosphate acetyltransferase
BF38_5335	COG3829	transcription factor binding
BF38_5335	COG3290	protein histidine kinase activity
BF38_5337	COG0584	glycerophosphoryl diester phosphodiesterase
BF38_5338	COG3093	addiction module antidote protein HigA
BF38_534	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF38_5340	COG0745	RESPONSE REGULATOR receiver
BF38_5341	COG0750	zinc metalloprotease
BF38_5342	COG0497	DNA recombination
BF38_5344	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF38_5346	COG0142	geranyltranstransferase activity
BF38_535	COG5002	protein histidine kinase activity
BF38_5351	COG1302	Protein conserved in bacteria
BF38_5352	COG0439	Biotin carboxylase
BF38_5353	COG0511	ligase activity, forming carbon-carbon bonds
BF38_536	COG4191	Histidine kinase
BF38_5362	COG3854	ATPases associated with a variety of cellular activities
BF38_5367	COG0006	proline dipeptidase activity
BF38_537	COG2267	carboxylic ester hydrolase activity
BF38_5370	COG3872	metal-dependent enzyme
BF38_5371	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF38_5376	COG0095	Lipoate-protein ligase
BF38_5377	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF38_5378	COG1609	Transcriptional regulator
BF38_538	COG1368	sulfuric ester hydrolase activity
BF38_5380	COG2076	Multidrug Resistance protein
BF38_5381	COG2076	Multidrug Resistance protein
BF38_5388	COG1131	(ABC) transporter
BF38_5389	COG1725	Transcriptional regulator
BF38_5395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF38_5406	COG4970	Tfp pilus assembly protein FimT
BF38_5408	COG1459	type II secretion system
BF38_541	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF38_5415	COG0791	NLP P60 protein
BF38_542	COG1116	anion transmembrane transporter activity
BF38_5421	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_543	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF38_5446	COG0494	nUDIX hydrolase
BF38_5447	COG1401	restriction endodeoxyribonuclease activity
BF38_5449	COG2003	Belongs to the UPF0758 family
BF38_546	COG0546	phosphoglycolate phosphatase activity
BF38_5464	COG2304	oxidoreductase activity
BF38_5468	COG0697	spore germination
BF38_5469	COG3316	Transposase and inactivated derivatives
BF38_5470	COG0584	glycerophosphoryl diester phosphodiesterase
BF38_548	COG0494	nUDIX hydrolase
BF38_5481	COG1396	sequence-specific DNA binding
BF38_5482	COG0252	asparaginase activity
BF38_5483	COG3104	oligopeptide transport
BF38_5484	COG2801	Transposase and inactivated derivatives
BF38_5492	COG0457	Tetratricopeptide repeat
BF38_5492	COG0463	Glycosyl transferase, family 2
BF38_5495	COG1216	Glycosyl transferase, family 2
BF38_5498	COG1131	(ABC) transporter
BF38_55	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF38_5500	COG1695	Transcriptional regulator
BF38_5510	COG0463	Glycosyl transferase, family 2
BF38_553	COG0288	reversible hydration of carbon dioxide
BF38_5539	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_555	COG1271	oxidase subunit
BF38_5555	COG4974	Belongs to the 'phage' integrase family
BF38_5559	COG2239	Acts as a magnesium transporter
BF38_556	COG1294	oxidase, subunit
BF38_5569	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5587	COG2814	Major facilitator Superfamily
BF38_5588	COG0583	DNA-binding transcription factor activity
BF38_5597	COG0318	PFAM AMP-dependent synthetase and ligase
BF38_5598	COG1605	Chorismate mutase
BF38_5598	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF38_5599	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF38_5599	COG1605	Chorismate mutase
BF38_56	COG0295	cytidine deaminase activity
BF38_560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_5601	COG0658	competence protein
BF38_5601	COG2333	competence protein COMEC
BF38_5607	COG3321	synthase
BF38_5607	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF38_5607	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5607	COG4221	oxidoreductase activity
BF38_5607	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF38_5607	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5607	COG3321	synthase
BF38_5607	COG4221	oxidoreductase activity
BF38_5608	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5608	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF38_5608	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF38_5608	COG3321	synthase
BF38_5608	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF38_5609	COG3321	synthase
BF38_5609	COG1028	Short-chain dehydrogenase reductase Sdr
BF38_5609	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF38_5609	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF38_5609	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF38_5610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF38_5610	COG0300	oxidoreductase activity
BF38_5610	COG4221	oxidoreductase activity
BF38_5610	COG3321	synthase
BF38_5611	COG3321	synthase
BF38_5611	COG0300	oxidoreductase activity
BF38_5611	COG4221	oxidoreductase activity
BF38_5611	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF38_5612	COG1063	alcohol dehydrogenase
BF38_5613	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF38_5615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF38_5615	COG2070	2-Nitropropane dioxygenase
BF38_5616	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_5617	COG0250	Participates in transcription elongation, termination and antitermination
BF38_5619	COG0789	Transcriptional regulator
BF38_5619	COG4978	Transcriptional regulator
BF38_5633	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF38_565	COG1842	Phage shock protein A
BF38_5660	COG3481	metal-dependent phosphohydrolase, HD sub domain
BF38_5677	COG3091	SprT-like family
BF38_57	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF38_5707	COG3409	Peptidoglycan-binding domain 1 protein
BF38_5707	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF38_5708	COG3409	Peptidoglycan-binding domain 1 protein
BF38_5708	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF38_572	COG5002	protein histidine kinase activity
BF38_573	COG0745	RESPONSE REGULATOR receiver
BF38_5734	COG4193	domain, Protein
BF38_5734	COG5263	repeat protein
BF38_5766	COG1876	peptidase activity
BF38_579	COG1597	lipid kinase activity
BF38_5810	COG0358	DNA primase activity
BF38_5824	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF38_5825	COG0187	DNA topoisomerase II activity
BF38_584	COG0586	Pfam SNARE associated Golgi protein
BF38_586	COG0577	efflux transmembrane transporter activity
BF38_587	COG1136	(ABC) transporter
BF38_5879	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF38_588	COG3708	Transcriptional regulator
BF38_588	COG2207	Transcriptional regulator
BF38_589	COG0745	RESPONSE REGULATOR receiver
BF38_59	COG1480	7TM receptor with intracellular HD hydrolase
BF38_590	COG2205	protein histidine kinase activity
BF38_5908	COG4990	cell redox homeostasis
BF38_591	COG0577	efflux transmembrane transporter activity
BF38_592	COG0577	efflux transmembrane transporter activity
BF38_593	COG1136	(ABC) transporter
BF38_5934	COG3764	Sortase (surface protein transpeptidase)
BF38_5939	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF38_5939	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF38_594	COG0577	efflux transmembrane transporter activity
BF38_5996	COG0210	DNA helicase
BF38_60	COG1702	phosphate starvation-inducible protein PhoH
BF38_601	COG3964	amidohydrolase
BF38_607	COG4948	Mandelate Racemase Muconate Lactonizing
BF38_609	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF38_610	COG0596	Alpha beta hydrolase
BF38_6102	COG2815	serine threonine protein kinase
BF38_6102	COG0515	serine threonine protein kinase
BF38_6104	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BF38_6105	COG2369	cell adhesion
BF38_6106	COG5518	Phage portal protein
BF38_6108	COG5484	DNA packaging
BF38_611	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF38_612	COG1169	isochorismate synthase
BF38_6128	COG1484	DNA-dependent DNA replication
BF38_613	COG1575	Belongs to the MenA family. Type 1 subfamily
BF38_614	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF38_6140	COG1396	sequence-specific DNA binding
BF38_615	COG1278	Cold shock
BF38_6161	COG1131	(ABC) transporter
BF38_6162	COG0842	Transport permease protein
BF38_6170	COG3104	oligopeptide transport
BF38_6173	COG3012	SEC-C Motif Domain Protein
BF38_6173	COG1405	negative regulation of cell septum assembly
BF38_6177	COG1192	Involved in chromosome partitioning
BF38_6181	COG2329	Antibiotic biosynthesis monooxygenase
BF38_6186	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF38_6188	COG5444	nuclease activity
BF38_619	COG0058	SHG alpha-glucan phosphorylase activity
BF38_6191	COG4824	toxin secretion phage lysis holin
BF38_6206	COG4653	Phage capsid family
BF38_6207	COG1192	Involved in chromosome partitioning
BF38_621	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF38_6214	COG4166	transmembrane transport
BF38_6217	COG0270	DNA (cytosine-5-)-methyltransferase activity
BF38_622	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF38_6223	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF38_6228	COG4974	Belongs to the 'phage' integrase family
BF38_6237	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF38_6237	COG0551	DNA topoisomerase type I activity
BF38_625	COG0039	L-malate dehydrogenase activity
BF38_6253	COG0791	NLP P60 protein
BF38_6253	COG0741	lytic transglycosylase activity
BF38_627	COG1595	DNA-templated transcription, initiation
BF38_63	COG1610	YqeY-like protein
BF38_646	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF38_65	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF38_654	COG1285	pathogenesis
BF38_656	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF38_658	COG2155	Conserved Protein
BF38_659	COG1098	S1 RNA binding domain
BF38_66	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF38_660	COG0436	Aminotransferase
BF38_661	COG1522	sequence-specific DNA binding
BF38_662	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF38_663	COG2267	carboxylic ester hydrolase activity
BF38_665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF38_669	COG5018	Exonuclease
BF38_670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF38_673	COG0423	glycine-tRNA ligase activity
BF38_674	COG2050	protein possibly involved in aromatic compounds catabolism
BF38_676	COG1268	BioY protein
BF38_678	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF38_679	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF38_682	COG3584	3D domain protein
BF38_685	COG1252	NADH dehydrogenase
BF38_688	COG3708	Transcriptional regulator
BF38_691	COG1683	Conserved Protein
BF38_695	COG0316	Belongs to the HesB IscA family
BF38_698	COG1252	NADH dehydrogenase
BF38_70	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF38_701	COG0390	transport system, permease component
BF38_702	COG2824	Alkylphosphonate utilization operon protein PhnA
BF38_706	COG4837	Protein of unknown function (DUF1462)
BF38_707	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF38_709	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF38_710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF38_712	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF38_714	COG0647	UMP catabolic process
BF38_716	COG2445	Protein of unknown function DUF86
BF38_717	COG1494	fructose-1,6-bisphosphatase
BF38_72	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF38_720	COG4470	Protein conserved in bacteria
BF38_722	COG0789	Transcriptional regulator
BF38_723	COG4377	Putative membrane peptidase family (DUF2324)
BF38_728	COG0739	heme binding
BF38_73	COG1733	regulation of RNA biosynthetic process
BF38_730	COG3377	Domain of unknown function (DUF1805)
BF38_731	COG0737	Belongs to the 5'-nucleotidase family
BF38_732	COG0719	Fe-S assembly protein
BF38_733	COG0822	iron-sulfur transferase activity
BF38_734	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF38_735	COG0719	Fe-S assembly protein
BF38_736	COG0396	ATPase activity
BF38_737	COG1464	Belongs to the NlpA lipoprotein family
BF38_738	COG1464	Belongs to the NlpA lipoprotein family
BF38_739	COG2011	ABC-type metal ion transport system permease component
BF38_742	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF38_743	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF38_745	COG1393	Belongs to the ArsC family
BF38_756	COG0039	L-malate dehydrogenase activity
BF38_763	COG1309	transcriptional regulator
BF38_764	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF38_765	COG1960	acyl-CoA dehydrogenase activity
BF38_766	COG0183	Belongs to the thiolase family
BF38_767	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF38_767	COG1024	Enoyl-CoA hydratase
BF38_769	COG1686	Belongs to the peptidase S11 family
BF38_772	COG0011	TIGRFAM Protein of
BF38_773	COG0840	transmembrane signaling receptor activity
BF38_777	COG2814	Major facilitator Superfamily
BF38_778	COG0531	amino acid
BF38_78	COG1466	dna polymerase III delta subunit
BF38_780	COG0706	membrane insertase activity
BF38_782	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF38_79	COG1466	dna polymerase III delta subunit
BF38_790	COG0586	Pfam SNARE associated Golgi protein
BF38_792	COG1376	ErfK ybiS ycfS ynhG family protein
BF38_793	COG0745	RESPONSE REGULATOR receiver
BF38_794	COG5002	protein histidine kinase activity
BF38_799	COG0840	transmembrane signaling receptor activity
BF38_800	COG2151	metal-sulfur cluster biosynthetic enzyme
BF38_801	COG3227	Zinc metalloprotease (Elastase)
BF38_802	COG1741	Belongs to the pirin family
BF38_805	COG0475	glutathione-regulated potassium exporter activity
BF38_806	COG0490	domain, Protein
BF38_807	COG1115	amino acid carrier protein
BF38_808	COG0783	Belongs to the Dps family
BF38_81	COG0658	competence protein
BF38_81	COG2333	competence protein COMEC
BF38_811	COG1611	Belongs to the LOG family
BF38_815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF38_816	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF38_817	COG1115	amino acid carrier protein
BF38_818	COG2910	NAD(P)H-binding
BF38_82	COG2131	deaminase
BF38_822	COG0656	L-ascorbic acid biosynthetic process
BF38_823	COG2814	Major facilitator Superfamily
BF38_824	COG1733	regulation of RNA biosynthetic process
BF38_826	COG1252	NADH dehydrogenase
BF38_827	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF38_828	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF38_83	COG1596	polysaccharide export
BF38_83	COG1555	photosystem II stabilization
BF38_832	COG0840	transmembrane signaling receptor activity
BF38_832	COG3290	protein histidine kinase activity
BF38_838	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF38_839	COG3223	Belongs to the PsiE family
BF38_84	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF38_85	COG2226	methyltransferase
BF38_857	COG0557	exoribonuclease II activity
BF38_858	COG1647	Serine aminopeptidase, S33
BF38_859	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF38_86	COG0799	negative regulation of ribosome biogenesis
BF38_860	COG1346	cytolysis
BF38_867	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF38_87	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF38_870	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF38_875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF38_878	COG2323	membrane
BF38_880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF38_882	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF38_884	COG1051	belongs to the nudix hydrolase family
BF38_886	COG0492	ferredoxin-NADP+ reductase activity
BF38_887	COG0457	Tetratricopeptide repeat
BF38_888	COG0110	maltose O-acetyltransferase activity
BF38_89	COG1534	Rna-binding protein
BF38_892	COG1950	PFAM Membrane protein of
BF38_894	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF38_895	COG0556	nucleotide-excision repair
BF38_898	COG0789	Transcriptional regulator
BF38_903	COG2855	membrane
BF38_904	COG0583	DNA-binding transcription factor activity
BF38_906	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF38_909	COG1132	(ABC) transporter
BF38_91	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF38_910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF38_911	COG3409	Peptidoglycan-binding domain 1 protein
BF38_911	COG0793	Belongs to the peptidase S41A family
BF38_912	COG2177	Part of the ABC transporter FtsEX involved in
BF38_913	COG2884	Cell division ATP-binding protein ftsE
BF38_915	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF38_917	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF38_918	COG1278	Cold shock
BF38_919	COG1040	competence protein
BF38_92	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF38_920	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF38_921	COG1388	LysM domain
BF38_921	COG0791	NLP P60 protein
BF38_922	COG1733	regulation of RNA biosynthetic process
BF38_923	COG1307	EDD domain protein, DegV family
BF38_924	COG1739	Uncharacterized protein family UPF0029
BF38_925	COG1316	TRANSCRIPTIONal
BF38_926	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF38_927	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF38_928	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF38_930	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF38_930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF38_934	COG1486	melibiose metabolic process
BF38_935	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF38_936	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF38_938	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF38_940	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF38_942	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF38_943	COG1301	dicarboxylic acid transport
BF38_945	COG0346	lactoylglutathione lyase activity
BF38_946	COG1511	domain protein
BF38_947	COG0583	DNA-binding transcription factor activity
BF38_948	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF38_95	COG1191	sigma factor activity
BF38_950	COG1271	oxidase subunit
BF38_951	COG1294	oxidase, subunit
BF38_952	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF38_954	COG1620	l-lactate permease
BF38_956	COG2389	metal-binding protein
BF38_958	COG1368	sulfuric ester hydrolase activity
BF38_960	COG0791	NLP P60 protein
BF38_960	COG1388	LysM domain
BF38_961	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF38_963	COG1215	transferase activity, transferring glycosyl groups
BF38_965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF38_966	COG1388	LysM domain
BF38_966	COG3584	3D domain protein
BF38_97	COG1595	DNA-templated transcription, initiation
BF38_971	COG4715	Zinc finger, swim domain protein
BF38_972	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF38_978	COG1191	sigma factor activity
BF38_981	COG0577	efflux transmembrane transporter activity
BF38_982	COG1136	(ABC) transporter
BF38_989	COG5002	protein histidine kinase activity
BF38_99	COG0778	Nitroreductase
BF38_990	COG0745	RESPONSE REGULATOR receiver
BF38_991	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF38_994	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF38_995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF38_996	COG1215	transferase activity, transferring glycosyl groups