locus-tag	class	description
HBA75_00010	COG0592	DNA-directed DNA polymerase activity
HBA75_00015	COG2501	S4 domain
HBA75_00025	COG0187	DNA topoisomerase II activity
HBA75_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBA75_00145	COG0517	IMP dehydrogenase activity
HBA75_00145	COG0516	GMP reductase activity
HBA75_00150	COG1686	Belongs to the peptidase S11 family
HBA75_00180	COG1428	Deoxynucleoside kinase
HBA75_00185	COG1428	Deoxynucleoside kinase
HBA75_00190	COG1335	isochorismatase
HBA75_00195	COG0590	tRNA wobble adenosine to inosine editing
HBA75_00205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBA75_00260	COG1982	Orn Lys Arg decarboxylase major
HBA75_00270	COG0470	DNA polymerase III
HBA75_00275	COG1774	PSP1 C-terminal conserved region
HBA75_00285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HBA75_00305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBA75_00310	COG2002	toxin-antitoxin pair type II binding
HBA75_00320	COG0084	hydrolase, TatD family'
HBA75_00340	COG4466	Protein conserved in bacteria
HBA75_00355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HBA75_00360	COG0251	oxidation-reduction process
HBA75_00390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBA75_00395	COG2002	toxin-antitoxin pair type II binding
HBA75_00400	COG2244	polysaccharide biosynthetic process
HBA75_00405	COG3956	TIGRFAM MazG family protein
HBA75_00410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBA75_00430	COG1098	S1 RNA binding domain
HBA75_00445	COG2208	phosphoserine phosphatase activity
HBA75_00460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBA75_00475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBA75_00480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBA75_00485	COG0512	Glutamine amidotransferase of anthranilate synthase
HBA75_00490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_00495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBA75_00500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBA75_00505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBA75_00510	COG1396	sequence-specific DNA binding
HBA75_00515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBA75_00605	COG3880	PFAM UvrB UvrC protein
HBA75_00615	COG0542	response to heat
HBA75_00620	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBA75_00630	COG4956	integral membrane protein (PIN domain superfamily)
HBA75_00650	COG1045	serine acetyltransferase
HBA75_00665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBA75_00670	COG3688	RNA-binding protein containing a PIN domain
HBA75_00685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HBA75_00690	COG0250	Participates in transcription elongation, termination and antitermination
HBA75_00695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HBA75_00715	COG2813	Specifically methylates the guanine in position
HBA75_00730	COG1358	cellular component organization or biogenesis
HBA75_00735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HBA75_00800	COG0255	Belongs to the universal ribosomal protein uL29 family
HBA75_00860	COG0201	protein transport
HBA75_00870	COG0024	Methionine aminopeptidase
HBA75_00880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HBA75_00915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBA75_00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_00945	COG0489	protein tyrosine kinase activity
HBA75_00955	COG2194	sulfuric ester hydrolase activity
HBA75_00960	COG0726	polysaccharide deacetylase
HBA75_01030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBA75_01035	COG4856	YbbR-like protein
HBA75_01075	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_01080	COG2011	ABC-type metal ion transport system permease component
HBA75_01085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBA75_01090	COG1464	Belongs to the NlpA lipoprotein family
HBA75_01095	COG0604	alcohol dehydrogenase
HBA75_01105	COG0277	FAD linked oxidase domain protein
HBA75_01110	COG2271	Major facilitator Superfamily
HBA75_01120	COG2814	Major facilitator Superfamily
HBA75_01135	COG0601	transmembrane transport
HBA75_01145	COG0444	Belongs to the ABC transporter superfamily
HBA75_01150	COG4608	Belongs to the ABC transporter superfamily
HBA75_01160	COG4166	transmembrane transport
HBA75_01170	COG2207	Transcriptional regulator
HBA75_01185	COG4166	transmembrane transport
HBA75_01190	COG4166	transmembrane transport
HBA75_01195	COG0656	L-ascorbic acid biosynthetic process
HBA75_01210	COG4149	molybdate abc transporter
HBA75_01215	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBA75_01225	COG1910	domain protein
HBA75_01240	COG0697	spore germination
HBA75_01255	COG0204	Acyl-transferase
HBA75_01265	COG1609	Transcriptional regulator
HBA75_01275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_01290	COG5298	Protein conserved in bacteria
HBA75_01315	COG0488	(ABC) transporter
HBA75_01325	COG0747	negative chemotaxis
HBA75_01355	COG0444	Belongs to the ABC transporter superfamily
HBA75_01360	COG4608	Belongs to the ABC transporter superfamily
HBA75_01365	COG0561	phosphatase activity
HBA75_01395	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HBA75_01400	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBA75_01410	COG0531	amino acid
HBA75_01415	COG2814	Major facilitator Superfamily
HBA75_01425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBA75_01435	COG4294	response to UV
HBA75_01440	COG0705	Rhomboid family
HBA75_01450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HBA75_01455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBA75_01460	COG0864	Transcriptional regulator
HBA75_01465	COG2337	Toxic component of a toxin-antitoxin (TA) module
HBA75_01470	COG2183	response to ionizing radiation
HBA75_01580	COG0802	atpase or kinase
HBA75_01585	COG1214	PFAM Peptidase M22, glycoprotease
HBA75_01590	COG0456	acetyltransferase
HBA75_01600	COG0488	(ABC) transporter
HBA75_01615	COG1266	CAAX protease self-immunity
HBA75_01635	COG2252	PERMEase
HBA75_01645	COG5002	protein histidine kinase activity
HBA75_01670	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBA75_01710	COG2205	protein histidine kinase activity
HBA75_01715	COG0745	RESPONSE REGULATOR receiver
HBA75_01745	COG2226	methyltransferase
HBA75_01790	COG1215	transferase activity, transferring glycosyl groups
HBA75_01810	COG0697	spore germination
HBA75_01840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBA75_01845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBA75_01850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBA75_01860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBA75_01875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBA75_01885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBA75_01895	COG0151	Belongs to the GarS family
HBA75_01920	COG0210	DNA helicase
HBA75_01930	COG4851	CamS sex pheromone cAM373 precursor
HBA75_01945	COG1335	isochorismatase
HBA75_01955	COG2011	ABC-type metal ion transport system permease component
HBA75_01960	COG1464	Belongs to the NlpA lipoprotein family
HBA75_01975	COG0003	Pfam Anion-transporting ATPase
HBA75_01980	COG1846	Transcriptional regulator
HBA75_01985	COG4682	membrane
HBA75_02005	COG1597	lipid kinase activity
HBA75_02015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBA75_02025	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_02030	COG2076	Multidrug Resistance protein
HBA75_02065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_02075	COG0582	viral genome integration into host DNA
HBA75_02090	COG3620	sequence-specific DNA binding
HBA75_02200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HBA75_02230	COG1263	PTS System
HBA75_02230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_02235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_02250	COG0463	Glycosyl transferase, family 2
HBA75_02260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBA75_02260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HBA75_02280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBA75_02300	COG1228	amidohydrolase
HBA75_02305	COG1090	epimerase
HBA75_02335	COG1988	membrane-bound metal-dependent
HBA75_02340	COG1194	a g-specific adenine glycosylase
HBA75_02365	COG1132	(ABC) transporter
HBA75_02370	COG4129	membrane
HBA75_02375	COG0070	glutamate synthase
HBA75_02375	COG0067	glutamate synthase
HBA75_02375	COG0069	glutamate synthase activity
HBA75_02385	COG4555	ABC transporter
HBA75_02405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBA75_02410	COG0735	belongs to the Fur family
HBA75_02530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HBA75_02555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBA75_02565	COG2766	serine protein kinase
HBA75_02585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBA75_02595	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBA75_02600	COG2268	Band 7 protein
HBA75_02610	COG3290	protein histidine kinase activity
HBA75_02615	COG4565	transcriptional regulatory protein
HBA75_02620	COG2851	Citrate transporter
HBA75_02640	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_02650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HBA75_02655	COG3842	ATPase activity
HBA75_02660	COG1175	transmembrane transport
HBA75_02665	COG0395	ABC-type sugar transport system, permease component
HBA75_02680	COG2801	Transposase and inactivated derivatives
HBA75_02685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HBA75_02690	COG0745	RESPONSE REGULATOR receiver
HBA75_02695	COG5002	protein histidine kinase activity
HBA75_02695	COG3850	Histidine kinase
HBA75_02705	COG4990	cell redox homeostasis
HBA75_02715	COG3290	protein histidine kinase activity
HBA75_02720	COG4565	transcriptional regulatory protein
HBA75_02725	COG3493	citrate carrier protein
HBA75_02730	COG0281	malic enzyme
HBA75_02740	COG0697	spore germination
HBA75_02745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_02755	COG5002	protein histidine kinase activity
HBA75_02765	COG0456	acetyltransferase
HBA75_02765	COG0454	-acetyltransferase
HBA75_02770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBA75_02780	COG3383	formate dehydrogenase (NAD+) activity
HBA75_02785	COG2427	Protein of unknown function (DUF1641)
HBA75_02800	COG0531	amino acid
HBA75_02810	COG0640	Transcriptional regulator
HBA75_02815	COG2217	Heavy metal translocating P-type atpase
HBA75_02820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBA75_02835	COG3227	Zinc metalloprotease (Elastase)
HBA75_02855	COG2720	vancomycin resistance protein
HBA75_02860	COG1316	TRANSCRIPTIONal
HBA75_02865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_02875	COG0346	lactoylglutathione lyase activity
HBA75_02880	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_02885	COG1253	flavin adenine dinucleotide binding
HBA75_02890	COG1027	Aspartate ammonia-lyase
HBA75_02895	COG1620	l-lactate permease
HBA75_02910	COG3104	oligopeptide transport
HBA75_02915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_02920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_02925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_02935	COG2226	methyltransferase
HBA75_02945	COG3344	reverse transcriptase
HBA75_02955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBA75_02960	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HBA75_02970	COG4548	von Willebrand factor, type A
HBA75_02975	COG0714	Associated with various cellular activities
HBA75_02995	COG0531	amino acid
HBA75_03000	COG2188	Transcriptional regulator
HBA75_03005	COG1263	PTS System
HBA75_03005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_03010	COG0366	Alpha amylase catalytic
HBA75_03025	COG0697	spore germination
HBA75_03030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBA75_03035	COG1115	amino acid carrier protein
HBA75_03040	COG1126	abc transporter atp-binding protein
HBA75_03045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBA75_03050	COG0765	amino acid transport
HBA75_03055	COG0765	amino acid transport
HBA75_03060	COG0833	amino acid
HBA75_03085	COG2378	regulation of single-species biofilm formation
HBA75_03090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBA75_03095	COG5002	protein histidine kinase activity
HBA75_03110	COG0659	secondary active sulfate transmembrane transporter activity
HBA75_03125	COG2271	Major facilitator Superfamily
HBA75_03130	COG1846	Transcriptional regulator
HBA75_03135	COG0477	Major facilitator Superfamily
HBA75_03140	COG1609	Transcriptional regulator
HBA75_03145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBA75_03160	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBA75_03165	COG1879	ABC-type sugar transport system periplasmic component
HBA75_03190	COG1063	alcohol dehydrogenase
HBA75_03255	COG0840	transmembrane signaling receptor activity
HBA75_03260	COG3583	domain protein
HBA75_03260	COG3584	3D domain protein
HBA75_03265	COG1476	TRANSCRIPTIONal
HBA75_03285	COG3104	oligopeptide transport
HBA75_03290	COG1114	Component of the transport system for branched-chain amino acids
HBA75_03305	COG1113	amino acid transport
HBA75_03310	COG2252	PERMEase
HBA75_03325	COG2153	protein acetylation
HBA75_03335	COG0569	domain protein
HBA75_03335	COG0475	glutathione-regulated potassium exporter activity
HBA75_03345	COG1845	cytochrome c oxidase, subunit III
HBA75_03350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBA75_03360	COG0833	amino acid
HBA75_03365	COG4990	cell redox homeostasis
HBA75_03380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_03385	COG0697	spore germination
HBA75_03390	COG0531	amino acid
HBA75_03405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HBA75_03410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HBA75_03415	COG1918	ferrous iron import across plasma membrane
HBA75_03415	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HBA75_03420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBA75_03425	COG0573	inorganic phosphate transmembrane transporter activity
HBA75_03430	COG0581	inorganic phosphate transmembrane transporter activity
HBA75_03440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBA75_03560	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HBA75_03580	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBA75_03585	COG1116	anion transmembrane transporter activity
HBA75_03590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_03595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_03600	COG0352	thiamine-phosphate diphosphorylase activity
HBA75_03605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBA75_03610	COG2104	thiamine diphosphate biosynthetic process
HBA75_03620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_03625	COG0351	phosphomethylpyrimidine kinase
HBA75_03665	COG2205	protein histidine kinase activity
HBA75_03670	COG2814	Major facilitator Superfamily
HBA75_03675	COG1846	Transcriptional regulator
HBA75_03685	COG2252	PERMEase
HBA75_03690	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_03705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBA75_03710	COG1621	beta-fructofuranosidase activity
HBA75_03715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_03715	COG1263	PTS System
HBA75_03720	COG1609	Transcriptional regulator
HBA75_03775	COG0778	Nitroreductase
HBA75_03780	COG2719	SpoVR family
HBA75_03805	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBA75_03810	COG1937	Protein conserved in bacteria
HBA75_03815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_03815	COG0425	Belongs to the sulfur carrier protein TusA family
HBA75_03820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_03820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_03825	COG0425	Belongs to the sulfur carrier protein TusA family
HBA75_03830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_03830	COG0425	Belongs to the sulfur carrier protein TusA family
HBA75_03835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_03840	COG2210	Belongs to the sulfur carrier protein TusA family
HBA75_03845	COG0730	response to heat
HBA75_03855	COG1316	TRANSCRIPTIONal
HBA75_03860	COG0604	alcohol dehydrogenase
HBA75_03865	COG1283	sodium-dependent phosphate transmembrane transporter activity
HBA75_03880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_03880	COG3711	transcriptional antiterminator
HBA75_03885	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBA75_03890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBA75_03910	COG1388	LysM domain
HBA75_03910	COG3584	3D domain protein
HBA75_03915	COG0577	efflux transmembrane transporter activity
HBA75_03920	COG1136	(ABC) transporter
HBA75_03930	COG5522	Integral membrane protein (intg_mem_TP0381)
HBA75_03945	COG1114	Component of the transport system for branched-chain amino acids
HBA75_03950	COG3546	catalase activity
HBA75_03985	COG0586	Pfam SNARE associated Golgi protein
HBA75_04020	COG0531	amino acid
HBA75_04025	COG0475	glutathione-regulated potassium exporter activity
HBA75_04035	COG1737	Transcriptional regulator
HBA75_04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_04045	COG1263	PTS System
HBA75_04055	COG2259	Doxx family
HBA75_04075	COG1522	sequence-specific DNA binding
HBA75_04080	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HBA75_04080	COG0165	Argininosuccinate lyase
HBA75_04105	COG1309	transcriptional regulator
HBA75_04110	COG2814	Major facilitator Superfamily
HBA75_04115	COG1733	regulation of RNA biosynthetic process
HBA75_04130	COG4533	DNA binding
HBA75_04135	COG2211	Major facilitator Superfamily
HBA75_04150	COG0693	protein deglycase activity
HBA75_04165	COG0531	amino acid
HBA75_04170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBA75_04180	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_04185	COG1132	(ABC) transporter
HBA75_04190	COG1132	(ABC) transporter
HBA75_04200	COG0765	amino acid transport
HBA75_04205	COG1126	abc transporter atp-binding protein
HBA75_04220	COG0189	ligase activity
HBA75_04260	COG3527	Alpha-acetolactate decarboxylase
HBA75_04270	COG0561	phosphatase activity
HBA75_04280	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_04280	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_04285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBA75_04290	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_04305	COG0659	secondary active sulfate transmembrane transporter activity
HBA75_04310	COG2244	polysaccharide biosynthetic process
HBA75_04335	COG1024	Enoyl-CoA hydratase
HBA75_04355	COG1363	Peptidase, m42
HBA75_04390	COG0601	transmembrane transport
HBA75_04395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBA75_04400	COG0444	Belongs to the ABC transporter superfamily
HBA75_04405	COG4608	Belongs to the ABC transporter superfamily
HBA75_04415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_04435	COG0457	Tetratricopeptide repeat
HBA75_04545	COG0477	Major facilitator Superfamily
HBA75_04550	COG3290	protein histidine kinase activity
HBA75_04555	COG4565	transcriptional regulatory protein
HBA75_04560	COG3181	Tripartite tricarboxylate transporter family receptor
HBA75_04630	COG0789	Transcriptional regulator
HBA75_04630	COG4978	Transcriptional regulator
HBA75_04650	COG0305	Participates in initiation and elongation during chromosome replication
HBA75_04675	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_04690	COG0477	Major facilitator Superfamily
HBA75_04720	COG1073	alpha beta
HBA75_04765	COG1183	phosphatidylcholine synthase activity
HBA75_04780	COG2376	Dihydroxyacetone kinase
HBA75_04790	COG2376	Dihydroxyacetone kinase
HBA75_04825	COG1388	LysM domain
HBA75_04825	COG3584	3D domain protein
HBA75_04835	COG1388	LysM domain
HBA75_04835	COG0791	NLP P60 protein
HBA75_04840	COG2373	Large extracellular alpha-helical protein
HBA75_04860	COG0596	Alpha beta hydrolase
HBA75_04910	COG1191	sigma factor activity
HBA75_04920	COG2208	phosphoserine phosphatase activity
HBA75_04925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HBA75_04930	COG5002	protein histidine kinase activity
HBA75_04930	COG2205	protein histidine kinase activity
HBA75_04930	COG0784	Response regulator, receiver
HBA75_04970	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HBA75_04990	COG0420	3'-5' exonuclease activity
HBA75_04995	COG4717	serine-type aminopeptidase activity
HBA75_05010	COG4974	Belongs to the 'phage' integrase family
HBA75_05045	COG0346	lactoylglutathione lyase activity
HBA75_05050	COG0346	lactoylglutathione lyase activity
HBA75_05055	COG0457	Tetratricopeptide repeat
HBA75_05065	COG2267	carboxylic ester hydrolase activity
HBA75_05095	COG2140	Oxalate decarboxylase
HBA75_05105	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HBA75_05115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HBA75_05125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HBA75_05130	COG1695	Transcriptional regulator
HBA75_05155	COG3973	AAA domain
HBA75_05185	COG4980	gas vesicle protein
HBA75_05190	COG0537	adenosine 5'-monophosphoramidase activity
HBA75_05195	COG1131	(ABC) transporter
HBA75_05200	COG4473	ABC transporter
HBA75_05225	COG3402	PFAM membrane-flanked domain
HBA75_05230	COG3428	Bacterial PH domain
HBA75_05270	COG0697	spore germination
HBA75_05275	COG3402	PFAM membrane-flanked domain
HBA75_05280	COG3428	Bacterial PH domain
HBA75_05285	COG2329	Antibiotic biosynthesis monooxygenase
HBA75_05290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_05340	COG1309	transcriptional regulator
HBA75_05345	COG1511	domain protein
HBA75_05385	COG1609	Transcriptional regulator
HBA75_05395	COG1234	tRNA 3'-trailer cleavage
HBA75_05400	COG0095	Lipoate-protein ligase
HBA75_05410	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_05420	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBA75_05430	COG4208	sulfate ABC transporter
HBA75_05440	COG3209	COG3209 Rhs family protein
HBA75_05475	COG1408	metallophosphoesterase
HBA75_05480	COG1078	dGTPase activity
HBA75_05490	COG1595	DNA-templated transcription, initiation
HBA75_05495	COG3708	Transcriptional regulator
HBA75_05495	COG2207	Transcriptional regulator
HBA75_05500	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_05510	COG2205	protein histidine kinase activity
HBA75_05515	COG0745	RESPONSE REGULATOR receiver
HBA75_05535	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_05540	COG0501	Belongs to the peptidase M48B family
HBA75_05545	COG0840	transmembrane signaling receptor activity
HBA75_05550	COG3693	PFAM glycoside hydrolase, family 10
HBA75_05560	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBA75_05570	COG2224	Isocitrate lyase
HBA75_05585	COG1278	Cold shock
HBA75_05610	COG0398	Pfam SNARE associated Golgi protein
HBA75_05670	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBA75_05695	COG0367	asparagine synthase
HBA75_05705	COG0753	catalase activity
HBA75_05710	COG0004	ammonium transporteR
HBA75_05730	COG2996	Protein conserved in bacteria
HBA75_05745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_05765	COG0561	phosphatase activity
HBA75_05785	COG2267	carboxylic ester hydrolase activity
HBA75_05805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBA75_05810	COG5504	Zn-dependent protease
HBA75_05825	COG0180	Tryptophanyl-tRNA synthetase
HBA75_05850	COG0601	transmembrane transport
HBA75_05855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBA75_05860	COG0444	Belongs to the ABC transporter superfamily
HBA75_05865	COG4608	Belongs to the ABC transporter superfamily
HBA75_05870	COG0534	Mate efflux family protein
HBA75_05875	COG4166	transmembrane transport
HBA75_05890	COG0861	Integral membrane protein TerC family
HBA75_05910	COG1164	Oligoendopeptidase f
HBA75_05925	COG2346	COG2346, Truncated hemoglobins
HBA75_05930	COG4116	CYTH
HBA75_05940	COG2357	RelA SpoT domain protein
HBA75_05950	COG0564	pseudouridine synthase activity
HBA75_05965	COG0772	Belongs to the SEDS family
HBA75_05970	COG1216	Glycosyl transferase, family 2
HBA75_05990	COG0457	Tetratricopeptide repeat
HBA75_05990	COG0463	Glycosyl transferase, family 2
HBA75_06010	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBA75_06025	COG1091	dTDP-4-dehydrorhamnose reductase activity
HBA75_06070	COG2153	protein acetylation
HBA75_06080	COG2382	esterase
HBA75_06105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_06115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBA75_06115	COG0512	Glutamine amidotransferase of anthranilate synthase
HBA75_06150	COG1620	l-lactate permease
HBA75_06155	COG5634	Uncharacterized conserved protein (DUF2278)
HBA75_06205	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBA75_06215	COG1476	TRANSCRIPTIONal
HBA75_06275	COG1686	Belongs to the peptidase S11 family
HBA75_06280	COG0681	Belongs to the peptidase S26 family
HBA75_06315	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_06325	COG1176	ABC-type spermidine putrescine transport system, permease component I
HBA75_06330	COG1177	transmembrane transport
HBA75_06345	COG2409	Drug exporters of the RND superfamily
HBA75_06355	COG0564	pseudouridine synthase activity
HBA75_06365	COG2340	Cysteine-rich secretory protein family
HBA75_06370	COG0247	lactate metabolic process
HBA75_06375	COG0277	FAD linked oxidase domain protein
HBA75_06380	COG3835	regulator
HBA75_06390	COG0745	RESPONSE REGULATOR receiver
HBA75_06395	COG5002	protein histidine kinase activity
HBA75_06400	COG2186	Transcriptional regulator
HBA75_06420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HBA75_06425	COG2116	formate transmembrane transporter activity
HBA75_06430	COG0861	Integral membrane protein TerC family
HBA75_06435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBA75_06445	COG2030	dehydratase
HBA75_06465	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_06470	COG3243	poly(R)-hydroxyalkanoic acid synthase
HBA75_06480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBA75_06495	COG1840	ABC-type Fe3 transport system, periplasmic component
HBA75_06500	COG3842	ATPase activity
HBA75_06525	COG1349	DNA-binding transcription factor activity
HBA75_06535	COG0235	Class ii aldolase
HBA75_06545	COG2861	carbohydrate metabolic process
HBA75_06555	COG3852	Histidine kinase
HBA75_06560	COG1846	Transcriptional regulator
HBA75_06570	COG2318	DinB family
HBA75_06575	COG5002	protein histidine kinase activity
HBA75_06585	COG0720	synthase
HBA75_06600	COG4873	Protein conserved in bacteria
HBA75_06630	COG1780	Probably involved in ribonucleotide reductase function
HBA75_06635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBA75_06640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBA75_06645	COG1725	Transcriptional regulator
HBA75_06650	COG1131	(ABC) transporter
HBA75_06660	COG1131	(ABC) transporter
HBA75_06665	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HBA75_06680	COG1522	sequence-specific DNA binding
HBA75_06690	COG1335	isochorismatase
HBA75_06700	COG1619	proteins homologs of microcin C7 resistance protein MccF
HBA75_06705	COG2070	2-Nitropropane dioxygenase
HBA75_06710	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBA75_06720	COG1696	Membrane protein involved in D-alanine export
HBA75_06745	COG0716	FMN binding
HBA75_06800	COG1846	Transcriptional regulator
HBA75_06810	COG1301	dicarboxylic acid transport
HBA75_06815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBA75_06820	COG4709	membrane
HBA75_06825	COG3874	Sporulation protein YtfJ
HBA75_06845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_06850	COG0028	Belongs to the TPP enzyme family
HBA75_06855	COG0440	acetolactate synthase activity
HBA75_06930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HBA75_06945	COG1183	phosphatidylcholine synthase activity
HBA75_06950	COG1368	sulfuric ester hydrolase activity
HBA75_06960	COG0019	diaminopimelate decarboxylase activity
HBA75_06980	COG0529	Catalyzes the synthesis of activated sulfate
HBA75_06985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBA75_07005	COG1648	precorrin-2 dehydrogenase activity
HBA75_07010	COG0733	neurotransmitter:sodium symporter activity
HBA75_07035	COG1757	Na H antiporter
HBA75_07050	COG4758	membrane
HBA75_07055	COG4585	Histidine kinase
HBA75_07060	COG2197	response regulator
HBA75_07070	COG1114	Component of the transport system for branched-chain amino acids
HBA75_07140	COG0730	response to heat
HBA75_07145	COG0306	phosphate transporter
HBA75_07150	COG1392	Phosphate transport regulator
HBA75_07155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_07170	COG3852	Histidine kinase
HBA75_07175	COG1801	Protein of unknown function DUF72
HBA75_07185	COG0582	viral genome integration into host DNA
HBA75_07190	COG5002	protein histidine kinase activity
HBA75_07205	COG0392	lysyltransferase activity
HBA75_07205	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBA75_07220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBA75_07225	COG1686	Belongs to the peptidase S11 family
HBA75_07230	COG2715	membrane protein required for spore maturation
HBA75_07235	COG0700	Nucleoside recognition
HBA75_07240	COG1187	pseudouridine synthase activity
HBA75_07250	COG1333	cytochrome c biogenesis protein
HBA75_07255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HBA75_07260	COG0745	RESPONSE REGULATOR receiver
HBA75_07265	COG5002	protein histidine kinase activity
HBA75_07270	COG2096	Adenosyltransferase
HBA75_07290	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HBA75_07295	COG1141	Ferredoxin
HBA75_07305	COG0514	ATP-dependent DNA helicase (RecQ)
HBA75_07310	COG1266	CAAX protease self-immunity
HBA75_07325	COG0789	Transcriptional regulator
HBA75_07335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBA75_07355	COG0492	ferredoxin-NADP+ reductase activity
HBA75_07360	COG0252	asparaginase activity
HBA75_07430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBA75_07445	COG0142	geranyltranstransferase activity
HBA75_07455	COG0142	geranyltranstransferase activity
HBA75_07485	COG0457	Tetratricopeptide repeat
HBA75_07505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HBA75_07510	COG2010	Cytochrome c
HBA75_07510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HBA75_07515	COG4347	Protein of unknown function (DUF1405)
HBA75_07530	COG2738	Putative neutral zinc metallopeptidase
HBA75_07540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_07545	COG1694	Mazg nucleotide pyrophosphohydrolase
HBA75_07565	COG0438	transferase activity, transferring glycosyl groups
HBA75_07600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBA75_07600	COG1199	ATP-dependent helicase activity
HBA75_07620	COG3935	DnaD domain protein
HBA75_07625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBA75_07635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_07635	COG4499	WXG100 protein secretion system (Wss), protein YukC
HBA75_07690	COG0116	Belongs to the methyltransferase superfamily
HBA75_07710	COG0457	Tetratricopeptide repeat
HBA75_07730	COG1199	ATP-dependent helicase activity
HBA75_07735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HBA75_07745	COG0024	Methionine aminopeptidase
HBA75_07760	COG2233	PERMEase
HBA75_07765	COG2311	Membrane
HBA75_07775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBA75_07785	COG0456	acetyltransferase
HBA75_07820	COG0754	glutathionylspermidine amidase activity
HBA75_07835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBA75_07850	COG3944	biosynthesis protein
HBA75_07860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HBA75_07875	COG1215	transferase activity, transferring glycosyl groups
HBA75_07880	COG0438	transferase activity, transferring glycosyl groups
HBA75_07895	COG0454	-acetyltransferase
HBA75_07915	COG0328	RNA-DNA hybrid ribonuclease activity
HBA75_07955	COG3403	YqcI/YcgG family
HBA75_07965	COG1280	lysine exporter protein (LysE YggA)
HBA75_07985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_07990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBA75_08000	COG0475	glutathione-regulated potassium exporter activity
HBA75_08005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBA75_08010	COG4978	Transcriptional regulator
HBA75_08010	COG0789	Transcriptional regulator
HBA75_08020	COG2323	membrane
HBA75_08025	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HBA75_08065	COG1923	regulation of RNA biosynthetic process
HBA75_08075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HBA75_08080	COG1360	Flagellar Motor Protein
HBA75_08085	COG2201	protein-glutamate methylesterase activity
HBA75_08090	COG0643	Histidine kinase
HBA75_08090	COG2198	Histidine kinase
HBA75_08095	COG1776	CheC inhibitor of MCP methylation
HBA75_08095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_08110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HBA75_08130	COG1256	bacterial-type flagellum assembly
HBA75_08135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_08140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HBA75_08155	COG1815	bacterial-type flagellum-dependent cell motility
HBA75_08160	COG1558	bacterial-type flagellum-dependent cell motility
HBA75_08170	COG1766	The M ring may be actively involved in energy transduction
HBA75_08175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_08185	COG1157	protein secretion by the type III secretion system
HBA75_08220	COG0835	chemotaxis
HBA75_08220	COG0784	Response regulator, receiver
HBA75_08230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_08235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_08240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_08245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HBA75_08250	COG0741	lytic transglycosylase activity
HBA75_08260	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_08265	COG1776	CheC inhibitor of MCP methylation
HBA75_08265	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HBA75_08275	COG1338	Plays a role in the flagellum-specific transport system
HBA75_08280	COG1987	bacterial-type flagellum assembly
HBA75_08290	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBA75_08295	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HBA75_08300	COG1419	protein localization to endoplasmic reticulum
HBA75_08305	COG4786	Flagellar basal body rod
HBA75_08310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBA75_08355	COG2329	Antibiotic biosynthesis monooxygenase
HBA75_08380	COG0583	DNA-binding transcription factor activity
HBA75_08400	COG1234	tRNA 3'-trailer cleavage
HBA75_08430	COG1686	Belongs to the peptidase S11 family
HBA75_08435	COG0406	alpha-ribazole phosphatase activity
HBA75_08465	COG0367	asparagine synthase
HBA75_08495	COG1802	Transcriptional regulator
HBA75_08500	COG0697	spore germination
HBA75_08510	COG0523	cobalamin synthesis protein
HBA75_08515	COG0701	Predicted permease
HBA75_08530	COG1757	Na H antiporter
HBA75_08535	COG0789	Transcriptional regulator
HBA75_08565	COG0534	Mate efflux family protein
HBA75_08570	COG3340	Belongs to the peptidase S51 family
HBA75_08590	COG0785	Cytochrome C biogenesis protein
HBA75_08595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_08615	COG2733	membrane
HBA75_08650	COG1131	(ABC) transporter
HBA75_08670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBA75_08675	COG0528	UMP kinase activity
HBA75_08685	COG1027	Aspartate ammonia-lyase
HBA75_08690	COG2801	Transposase and inactivated derivatives
HBA75_08705	COG0281	malic enzyme
HBA75_08710	COG4191	Histidine kinase
HBA75_08715	COG0784	Response regulator, receiver
HBA75_08770	COG2814	Major facilitator Superfamily
HBA75_08785	COG1695	Transcriptional regulator
HBA75_08800	COG0477	Major facilitator Superfamily
HBA75_08815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBA75_08835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBA75_08855	COG0733	neurotransmitter:sodium symporter activity
HBA75_08865	COG5566	PFAM Mor transcription activator
HBA75_08870	COG2323	membrane
HBA75_08890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBA75_08900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_08905	COG0028	Belongs to the TPP enzyme family
HBA75_08925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBA75_08945	COG2814	Major facilitator Superfamily
HBA75_08950	COG3384	dioxygenase
HBA75_08960	COG3279	Response regulator of the LytR AlgR family
HBA75_08965	COG0427	acetyl-CoA hydrolase
HBA75_08985	COG4166	transmembrane transport
HBA75_08990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_09010	COG1914	H( )-stimulated, divalent metal cation uptake system
HBA75_09025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBA75_09030	COG0531	amino acid
HBA75_09060	COG2309	aminopeptidase activity
HBA75_09075	COG0456	acetyltransferase
HBA75_09125	COG1266	CAAX protease self-immunity
HBA75_09130	COG1309	transcriptional regulator
HBA75_09135	COG2390	Transcriptional regulator
HBA75_09145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_09150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HBA75_09160	COG4846	Membrane protein involved in cytochrome C biogenesis
HBA75_09180	COG0583	DNA-binding transcription factor activity
HBA75_09195	COG0006	proline dipeptidase activity
HBA75_09205	COG2132	Multicopper oxidase
HBA75_09220	COG1309	transcriptional regulator
HBA75_09225	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HBA75_09310	COG1114	Component of the transport system for branched-chain amino acids
HBA75_09320	COG1276	copper resistance
HBA75_09320	COG2372	response to copper ion
HBA75_09325	COG4549	nuclear export factor GLE1
HBA75_09345	COG0583	DNA-binding transcription factor activity
HBA75_09350	COG1959	2 iron, 2 sulfur cluster binding
HBA75_09360	COG0778	Nitroreductase
HBA75_09370	COG0628	permease
HBA75_09380	COG1231	oxidoreductase activity
HBA75_09385	COG0523	cobalamin synthesis protein
HBA75_09395	COG0411	ABC transporter
HBA75_09415	COG0583	DNA-binding transcription factor activity
HBA75_09445	COG1271	oxidase subunit
HBA75_09450	COG1294	oxidase, subunit
HBA75_09460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HBA75_09470	COG1216	Glycosyl transferase, family 2
HBA75_09510	COG1686	Belongs to the peptidase S11 family
HBA75_09525	COG0791	NLP P60 protein
HBA75_09525	COG1388	LysM domain
HBA75_09535	COG1132	(ABC) transporter
HBA75_09540	COG0745	RESPONSE REGULATOR receiver
HBA75_09545	COG5002	protein histidine kinase activity
HBA75_09555	COG0300	oxidoreductase activity
HBA75_09585	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_09590	COG0460	homoserine dehydrogenase
HBA75_09615	COG1316	TRANSCRIPTIONal
HBA75_09625	COG0745	RESPONSE REGULATOR receiver
HBA75_09630	COG5002	protein histidine kinase activity
HBA75_09645	COG1285	pathogenesis
HBA75_09650	COG1247	-acetyltransferase
HBA75_09660	COG4264	IucA IucC family
HBA75_09665	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_09680	COG1082	Xylose isomerase domain protein TIM barrel
HBA75_09690	COG2814	Major facilitator Superfamily
HBA75_09695	COG1279	arginine transmembrane transporter activity
HBA75_09700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_09710	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBA75_09750	COG0577	efflux transmembrane transporter activity
HBA75_09755	COG2002	toxin-antitoxin pair type II binding
HBA75_09760	COG1404	Belongs to the peptidase S8 family
HBA75_09765	COG0640	Transcriptional regulator
HBA75_09770	COG0667	Aldo Keto reductase
HBA75_09775	COG2814	Major facilitator Superfamily
HBA75_09800	COG0840	transmembrane signaling receptor activity
HBA75_09815	COG3949	Membrane
HBA75_09820	COG0783	Belongs to the Dps family
HBA75_09835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_09845	COG1231	oxidoreductase activity
HBA75_09850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_09855	COG4989	oxidoreductase activity
HBA75_09865	COG0523	cobalamin synthesis protein
HBA75_09870	COG0456	acetyltransferase
HBA75_09875	COG0803	Belongs to the bacterial solute-binding protein 9 family
HBA75_09890	COG0702	epimerase
HBA75_09900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBA75_09910	COG4166	transmembrane transport
HBA75_09935	COG5337	Spore coat protein CotH
HBA75_09940	COG1051	belongs to the nudix hydrolase family
HBA75_09945	COG0586	Pfam SNARE associated Golgi protein
HBA75_09950	COG2244	polysaccharide biosynthetic process
HBA75_09960	COG0701	Predicted permease
HBA75_09965	COG3689	TIGRFAM TIGR03943 family protein
HBA75_09970	COG1607	acyl-coa hydrolase
HBA75_09980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBA75_09995	COG0702	epimerase
HBA75_10000	COG2839	Protein conserved in bacteria
HBA75_10005	COG1253	flavin adenine dinucleotide binding
HBA75_10020	COG1114	Component of the transport system for branched-chain amino acids
HBA75_10025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBA75_10045	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_10055	COG1876	peptidase activity
HBA75_10065	COG2211	Major facilitator Superfamily
HBA75_10080	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_10090	COG0561	phosphatase activity
HBA75_10105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBA75_10120	COG1819	glycosyl
HBA75_10125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_10130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_10160	COG0456	acetyltransferase
HBA75_10195	COG4499	WXG100 protein secretion system (Wss), protein YukC
HBA75_10275	COG3874	Sporulation protein YtfJ
HBA75_10280	COG2801	Transposase and inactivated derivatives
HBA75_10310	COG2226	methyltransferase
HBA75_10330	COG1082	Xylose isomerase domain protein TIM barrel
HBA75_10335	COG0346	lactoylglutathione lyase activity
HBA75_10345	COG0604	alcohol dehydrogenase
HBA75_10365	COG0426	domain, Protein
HBA75_10365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBA75_10375	COG0386	Belongs to the glutathione peroxidase family
HBA75_10380	COG1305	Transglutaminase-like
HBA75_10385	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HBA75_10390	COG0714	Associated with various cellular activities
HBA75_10395	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBA75_10400	COG1140	nitrate reductase beta subunit
HBA75_10405	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HBA75_10410	COG2181	nitrate reductase activity
HBA75_10415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_10420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBA75_10425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_10430	COG0303	'Molybdopterin
HBA75_10435	COG0314	molybdopterin synthase activity
HBA75_10445	COG2223	nitrite transmembrane transporter activity
HBA75_10465	COG1648	precorrin-2 dehydrogenase activity
HBA75_10475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HBA75_10475	COG1587	Uroporphyrinogen-III synthase
HBA75_10480	COG2146	nitrite reductase [NAD(P)H] activity
HBA75_10485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBA75_10540	COG2359	stage V sporulation protein S
HBA75_10565	COG0457	Tetratricopeptide repeat
HBA75_10580	COG1418	mRNA catabolic process
HBA75_10585	COG0488	(ABC) transporter
HBA75_10600	COG0629	single-stranded DNA binding
HBA75_10615	COG1413	lyase activity
HBA75_10635	COG2136	Putative SAM-dependent methyltransferase
HBA75_10635	COG2521	methyltransferase
HBA75_10640	COG0018	arginyl-trna synthetase
HBA75_10675	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_10700	COG0017	Asparaginyl-tRNA synthetase
HBA75_10705	COG0733	neurotransmitter:sodium symporter activity
HBA75_10730	COG2610	gluconate transmembrane transporter activity
HBA75_10740	COG1794	racemase activity, acting on amino acids and derivatives
HBA75_10750	COG0456	acetyltransferase
HBA75_10760	COG3655	Transcriptional regulator
HBA75_10765	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HBA75_10775	COG1131	(ABC) transporter
HBA75_10780	COG4473	ABC transporter
HBA75_10790	COG0546	phosphoglycolate phosphatase activity
HBA75_10805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_10820	COG0768	penicillin binding
HBA75_10830	COG0204	Acyl-transferase
HBA75_10835	COG1272	protein, Hemolysin III
HBA75_10845	COG0805	protein transport
HBA75_10855	COG1307	EDD domain protein, DegV family
HBA75_10865	COG1999	signal sequence binding
HBA75_10870	COG0071	Belongs to the small heat shock protein (HSP20) family
HBA75_10875	COG0367	asparagine synthase
HBA75_10895	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_10900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_10905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBA75_10930	COG1335	isochorismatase
HBA75_10950	COG0668	transmembrane transport
HBA75_10955	COG2203	Gaf domain
HBA75_10955	COG4585	Histidine kinase
HBA75_10960	COG2197	response regulator
HBA75_10965	COG1737	Transcriptional regulator
HBA75_10985	COG1064	alcohol dehydrogenase
HBA75_11000	COG1070	Carbohydrate kinase
HBA75_11010	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HBA75_11045	COG1125	glycine betaine transport
HBA75_11045	COG0517	IMP dehydrogenase activity
HBA75_11050	COG1174	glycine betaine transport
HBA75_11085	COG1253	flavin adenine dinucleotide binding
HBA75_11090	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_11095	COG5506	Protein of unknown function (DUF1694)
HBA75_11110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBA75_11115	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBA75_11120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBA75_11125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HBA75_11130	COG0456	acetyltransferase
HBA75_11135	COG3829	transcription factor binding
HBA75_11145	COG1509	lysine 2,3-aminomutase activity
HBA75_11180	COG0515	serine threonine protein kinase
HBA75_11180	COG3064	Membrane
HBA75_11180	COG4991	sh3 domain protein
HBA75_11190	COG0671	phosphoesterase, PA-phosphatase related
HBA75_11195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBA75_11200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_11300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_11300	COG4499	WXG100 protein secretion system (Wss), protein YukC
HBA75_11310	COG2814	Major facilitator Superfamily
HBA75_11315	COG4841	protein insertion into membrane
HBA75_11320	COG0372	Belongs to the citrate synthase family
HBA75_11325	COG2079	MmgE PrpD family protein
HBA75_11330	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HBA75_11335	COG1960	acyl-CoA dehydrogenase activity
HBA75_11340	COG2084	Dehydrogenase
HBA75_11350	COG1280	lysine exporter protein (LysE YggA)
HBA75_11355	COG1024	Enoyl-CoA hydratase
HBA75_11370	COG0420	3'-5' exonuclease activity
HBA75_11375	COG0419	ATPase involved in DNA repair
HBA75_11405	COG2223	nitrite transmembrane transporter activity
HBA75_11410	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_11415	COG1169	isochorismate synthase
HBA75_11420	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBA75_11425	COG1535	isochorismatase
HBA75_11425	COG3433	isochorismatase activity
HBA75_11430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_11435	COG3251	PFAM MbtH domain protein
HBA75_11440	COG2814	Major facilitator Superfamily
HBA75_11455	COG0776	regulation of translation
HBA75_11465	COG2318	DinB family
HBA75_11475	COG1115	amino acid carrier protein
HBA75_11495	COG1187	pseudouridine synthase activity
HBA75_11500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBA75_11505	COG1136	(ABC) transporter
HBA75_11515	COG2814	Major facilitator Superfamily
HBA75_11530	COG0028	Belongs to the TPP enzyme family
HBA75_11575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_11595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_11630	COG1247	-acetyltransferase
HBA75_11665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_11695	COG0583	DNA-binding transcription factor activity
HBA75_11700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBA75_11720	COG0583	DNA-binding transcription factor activity
HBA75_11725	COG2258	MOSC domain
HBA75_11740	COG1132	(ABC) transporter
HBA75_11775	COG1396	sequence-specific DNA binding
HBA75_11805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBA75_11810	COG1595	DNA-templated transcription, initiation
HBA75_11835	COG1649	PFAM Uncharacterised BCR, COG1649
HBA75_11860	COG2971	BadF BadG BcrA BcrD
HBA75_11870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBA75_11880	COG1846	Transcriptional regulator
HBA75_11895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_11925	COG2002	toxin-antitoxin pair type II binding
HBA75_11965	COG0582	viral genome integration into host DNA
HBA75_11995	COG0500	methyltransferase
HBA75_11995	COG3615	Tellurite resistance protein tehB
HBA75_12005	COG2226	methyltransferase
HBA75_12010	COG3961	Belongs to the TPP enzyme family
HBA75_12015	COG1846	Transcriptional regulator
HBA75_12045	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBA75_12075	COG2002	toxin-antitoxin pair type II binding
HBA75_12090	COG0730	response to heat
HBA75_12095	COG0110	maltose O-acetyltransferase activity
HBA75_12100	COG1686	Belongs to the peptidase S11 family
HBA75_12115	COG2814	Major facilitator Superfamily
HBA75_12135	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_12195	COG3344	reverse transcriptase
HBA75_12225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_12280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_12285	COG0768	penicillin binding
HBA75_12290	COG1595	DNA-templated transcription, initiation
HBA75_12300	COG0768	penicillin binding
HBA75_12315	COG1408	metallophosphoesterase
HBA75_12325	COG1131	(ABC) transporter
HBA75_12335	COG1309	transcriptional regulator
HBA75_12350	COG1960	acyl-CoA dehydrogenase activity
HBA75_12355	COG0439	Biotin carboxylase
HBA75_12360	COG0511	ligase activity, forming carbon-carbon bonds
HBA75_12365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBA75_12370	COG1024	Enoyl-CoA hydratase
HBA75_12375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBA75_12380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBA75_12390	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_12405	COG0572	uridine kinase
HBA75_12415	COG2318	DinB family
HBA75_12420	COG1686	Belongs to the peptidase S11 family
HBA75_12445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBA75_12460	COG3227	Zinc metalloprotease (Elastase)
HBA75_12465	COG2207	Transcriptional regulator
HBA75_12510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBA75_12550	COG2814	Major facilitator Superfamily
HBA75_12555	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_12560	COG1733	regulation of RNA biosynthetic process
HBA75_12615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_12625	COG2368	4-hydroxyphenylacetate
HBA75_12640	COG1063	alcohol dehydrogenase
HBA75_12650	COG2323	membrane
HBA75_12665	COG3386	PFAM SMP-30 Gluconolaconase
HBA75_12675	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
HBA75_12680	COG3773	Cell wall hydrolase
HBA75_12685	COG0596	Alpha beta hydrolase
HBA75_12700	COG0745	RESPONSE REGULATOR receiver
HBA75_12705	COG2205	protein histidine kinase activity
HBA75_12740	COG1136	(ABC) transporter
HBA75_12745	COG0577	efflux transmembrane transporter activity
HBA75_12780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_12790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBA75_12850	COG2124	cytochrome p450
HBA75_12885	COG0561	phosphatase activity
HBA75_12890	COG5002	protein histidine kinase activity
HBA75_12905	COG1819	glycosyl
HBA75_12910	COG1794	racemase activity, acting on amino acids and derivatives
HBA75_12935	COG2205	protein histidine kinase activity
HBA75_12950	COG0604	alcohol dehydrogenase
HBA75_12955	COG0671	phosphoesterase, PA-phosphatase related
HBA75_13020	COG2132	Multicopper oxidase
HBA75_13030	COG0789	Transcriptional regulator
HBA75_13050	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_13070	COG2801	Transposase and inactivated derivatives
HBA75_13085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_13090	COG0697	spore germination
HBA75_13135	COG2223	nitrite transmembrane transporter activity
HBA75_13150	COG0592	DNA-directed DNA polymerase activity
HBA75_13170	COG3878	Protein conserved in bacteria
HBA75_13190	COG4667	esterase of the alpha-beta hydrolase superfamily
HBA75_13230	COG0322	excinuclease ABC activity
HBA75_13280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBA75_13315	COG1011	Hydrolase
HBA75_13320	COG0745	RESPONSE REGULATOR receiver
HBA75_13325	COG5002	protein histidine kinase activity
HBA75_13340	COG1136	(ABC) transporter
HBA75_13345	COG0577	efflux transmembrane transporter activity
HBA75_13350	COG1073	alpha beta
HBA75_13360	COG2801	Transposase and inactivated derivatives
HBA75_13380	COG0076	glutamate decarboxylase activity
HBA75_13400	COG3227	Zinc metalloprotease (Elastase)
HBA75_13405	COG0737	Belongs to the 5'-nucleotidase family
HBA75_13420	COG0201	protein transport
HBA75_13425	COG0697	spore germination
HBA75_13430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_13470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_13485	COG2959	enzyme of heme biosynthesis
HBA75_13545	COG1309	transcriptional regulator
HBA75_13570	COG3284	Transcriptional regulator
HBA75_13590	COG1349	DNA-binding transcription factor activity
HBA75_13605	COG1959	2 iron, 2 sulfur cluster binding
HBA75_13620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBA75_13625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBA75_13630	COG0022	dehydrogenase e1 component
HBA75_13635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBA75_13645	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_13650	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBA75_13650	COG0456	acetyltransferase
HBA75_13690	COG4176	ABC-type proline glycine betaine transport system permease component
HBA75_13695	COG0517	IMP dehydrogenase activity
HBA75_13695	COG4175	Glycine betaine
HBA75_13725	COG2153	protein acetylation
HBA75_13730	COG3397	chitin binding
HBA75_13735	COG1819	glycosyl
HBA75_13755	COG2205	protein histidine kinase activity
HBA75_13760	COG2226	methyltransferase
HBA75_13765	COG2315	Protein conserved in bacteria
HBA75_13810	COG0456	acetyltransferase
HBA75_13815	COG3973	AAA domain
HBA75_13830	COG0514	ATP-dependent DNA helicase (RecQ)
HBA75_13870	COG2801	Transposase and inactivated derivatives
HBA75_13885	COG4637	Psort location Cytoplasmic, score
HBA75_13900	COG3397	chitin binding
HBA75_13915	COG1162	GTPase activity
HBA75_13920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBA75_13925	COG1115	amino acid carrier protein
HBA75_13930	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_13935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBA75_13945	COG3938	Belongs to the proline racemase family
HBA75_13950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBA75_13995	COG0586	Pfam SNARE associated Golgi protein
HBA75_14005	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBA75_14015	COG4166	transmembrane transport
HBA75_14030	COG4948	Mandelate Racemase Muconate Lactonizing
HBA75_14045	COG0667	Aldo Keto reductase
HBA75_14090	COG5002	protein histidine kinase activity
HBA75_14090	COG3850	Histidine kinase
HBA75_14095	COG0745	RESPONSE REGULATOR receiver
HBA75_14130	COG1164	Oligoendopeptidase f
HBA75_14135	COG1307	EDD domain protein, DegV family
HBA75_14175	COG2814	Major facilitator Superfamily
HBA75_14185	COG1664	Polymer-forming cytoskeletal
HBA75_14190	COG0789	Transcriptional regulator
HBA75_14195	COG4533	DNA binding
HBA75_14200	COG2814	Major facilitator Superfamily
HBA75_14200	COG0477	Major facilitator Superfamily
HBA75_14220	COG2261	transglycosylase associated protein
HBA75_14235	COG2226	methyltransferase
HBA75_14270	COG0436	Aminotransferase
HBA75_14275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HBA75_14285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HBA75_14325	COG0628	permease
HBA75_14335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_14340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_14345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_14385	COG2746	aminoglycoside 3-N-acetyltransferase activity
HBA75_14410	COG2318	DinB family
HBA75_14430	COG4912	Dna alkylation repair
HBA75_14435	COG0346	lactoylglutathione lyase activity
HBA75_14455	COG0861	Integral membrane protein TerC family
HBA75_14460	COG1368	sulfuric ester hydrolase activity
HBA75_14465	COG0488	(ABC) transporter
HBA75_14470	COG2409	Drug exporters of the RND superfamily
HBA75_14470	COG1033	growth of symbiont in host cell
HBA75_14475	COG1309	transcriptional regulator
HBA75_14485	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_14500	COG0287	Prephenate dehydrogenase
HBA75_14515	COG1605	Chorismate mutase
HBA75_14515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HBA75_14560	COG1388	LysM domain
HBA75_14560	COG3584	3D domain protein
HBA75_14570	COG0346	lactoylglutathione lyase activity
HBA75_14575	COG0277	FAD linked oxidase domain protein
HBA75_14605	COG1879	ABC-type sugar transport system periplasmic component
HBA75_14610	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBA75_14615	COG1172	Belongs to the binding-protein-dependent transport system permease family
HBA75_14625	COG2390	Transcriptional regulator
HBA75_14630	COG1070	Carbohydrate kinase
HBA75_14650	COG2329	Antibiotic biosynthesis monooxygenase
HBA75_14670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_14685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_14690	COG4187	Peptidase family M20/M25/M40
HBA75_14695	COG1414	Transcriptional regulator
HBA75_14700	COG0833	amino acid
HBA75_14750	COG2720	vancomycin resistance protein
HBA75_14755	COG1785	Belongs to the alkaline phosphatase family
HBA75_14765	COG3655	Transcriptional regulator
HBA75_14790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_14795	COG0346	lactoylglutathione lyase activity
HBA75_14820	COG0714	Associated with various cellular activities
HBA75_14845	COG0463	Glycosyl transferase, family 2
HBA75_14875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBA75_14880	COG0753	catalase activity
HBA75_14925	COG0714	Associated with various cellular activities
HBA75_14995	COG0778	Nitroreductase
HBA75_15000	COG1846	Transcriptional regulator
HBA75_15025	COG3831	ATPase activity
HBA75_15025	COG4884	unkown
HBA75_15050	COG0456	acetyltransferase
HBA75_15065	COG0697	spore germination
HBA75_15070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_15110	COG0730	response to heat
HBA75_15125	COG0833	amino acid
HBA75_15135	COG4335	DNA alkylation repair
HBA75_15190	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_15200	COG1984	allophanate hydrolase subunit 2
HBA75_15205	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HBA75_15210	COG1414	Transcriptional regulator
HBA75_15225	COG0640	Transcriptional regulator
HBA75_15240	COG1960	acyl-CoA dehydrogenase activity
HBA75_15260	COG2801	Transposase and inactivated derivatives
HBA75_15275	COG2801	Transposase and inactivated derivatives
HBA75_15300	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HBA75_15320	COG2801	Transposase and inactivated derivatives
HBA75_15340	COG0574	Belongs to the PEP-utilizing enzyme family
HBA75_15340	COG3848	Pyruvate phosphate dikinase
HBA75_15345	COG1819	glycosyl
HBA75_15350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_15355	COG5577	PFAM Coat F domain
HBA75_15360	COG3403	YqcI/YcgG family
HBA75_15365	COG1280	lysine exporter protein (LysE YggA)
HBA75_15370	COG1113	amino acid transport
HBA75_15400	COG1063	alcohol dehydrogenase
HBA75_15410	COG1027	Aspartate ammonia-lyase
HBA75_15415	COG0252	asparaginase activity
HBA75_15420	COG1396	sequence-specific DNA binding
HBA75_15465	COG5002	protein histidine kinase activity
HBA75_15490	COG2207	Transcriptional regulator
HBA75_15505	COG0322	excinuclease ABC activity
HBA75_15510	COG0531	amino acid
HBA75_15515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_15525	COG0281	malic enzyme
HBA75_15555	COG0531	amino acid
HBA75_15560	COG0697	spore germination
HBA75_15565	COG0784	Response regulator, receiver
HBA75_15570	COG4191	Histidine kinase
HBA75_15575	COG2066	Belongs to the glutaminase family
HBA75_15580	COG1115	amino acid carrier protein
HBA75_15590	COG2124	cytochrome p450
HBA75_15605	COG1309	transcriptional regulator
HBA75_15610	COG2814	Major facilitator Superfamily
HBA75_15615	COG1309	transcriptional regulator
HBA75_15625	COG1522	sequence-specific DNA binding
HBA75_15640	COG0346	lactoylglutathione lyase activity
HBA75_15690	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_15745	COG2814	Major facilitator Superfamily
HBA75_15755	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HBA75_15765	COG1690	Belongs to the RtcB family
HBA75_15775	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HBA75_15800	COG0577	efflux transmembrane transporter activity
HBA75_15820	COG5002	protein histidine kinase activity
HBA75_15820	COG3850	Histidine kinase
HBA75_15830	COG2364	Membrane
HBA75_15835	COG1846	Transcriptional regulator
HBA75_15840	COG0456	acetyltransferase
HBA75_15845	COG2808	Putative FMN-binding domain
HBA75_15850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_15885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBA75_15930	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_15930	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_16040	COG1876	peptidase activity
HBA75_16045	COG2843	Capsule synthesis protein
HBA75_16055	COG0477	Major facilitator Superfamily
HBA75_16070	COG1846	Transcriptional regulator
HBA75_16075	COG2814	Major facilitator Superfamily
HBA75_16085	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HBA75_16090	COG1131	(ABC) transporter
HBA75_16110	COG2031	fatty acid transporter
HBA75_16120	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBA75_16175	COG1288	antiporter activity
HBA75_16180	COG2356	endonuclease I
HBA75_16205	COG1733	regulation of RNA biosynthetic process
HBA75_16210	COG0778	Nitroreductase
HBA75_16220	COG0469	pyruvate kinase activity
HBA75_16240	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_16250	COG1131	(ABC) transporter
HBA75_16275	COG1011	Hydrolase
HBA75_16315	COG0628	permease
HBA75_16345	COG0500	methyltransferase
HBA75_16385	COG1253	flavin adenine dinucleotide binding
HBA75_16390	COG0789	Transcriptional regulator
HBA75_16400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBA75_16430	COG0697	spore germination
HBA75_16435	COG1357	PFAM Pentapeptide repeats (8 copies)
HBA75_16440	COG3813	Protein conserved in bacteria
HBA75_16445	COG2706	6-phosphogluconolactonase activity
HBA75_16450	COG1070	Carbohydrate kinase
HBA75_16465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBA75_16470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HBA75_16475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBA75_16480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBA75_16485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBA75_16490	COG0604	alcohol dehydrogenase
HBA75_16495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_16505	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_16520	COG0840	transmembrane signaling receptor activity
HBA75_16530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_16530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_16535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBA75_16535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBA75_16540	COG1733	regulation of RNA biosynthetic process
HBA75_16555	COG0656	L-ascorbic acid biosynthetic process
HBA75_16560	COG2814	Major facilitator Superfamily
HBA75_16585	COG2824	Alkylphosphonate utilization operon protein PhnA
HBA75_16590	COG0659	secondary active sulfate transmembrane transporter activity
HBA75_16605	COG0814	amino acid
HBA75_16630	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_16645	COG1733	regulation of RNA biosynthetic process
HBA75_16650	COG2188	Transcriptional regulator
HBA75_16655	COG0673	inositol 2-dehydrogenase activity
HBA75_16660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HBA75_16665	COG1733	regulation of RNA biosynthetic process
HBA75_16670	COG1733	regulation of RNA biosynthetic process
HBA75_16705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_16730	COG0384	phenazine biosynthesis protein PhzF
HBA75_16740	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_16760	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_16765	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBA75_16770	COG1733	regulation of RNA biosynthetic process
HBA75_16785	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_16790	COG2801	Transposase and inactivated derivatives
HBA75_16810	COG1191	sigma factor activity
HBA75_16895	COG1151	hydroxylamine reductase activity
HBA75_16905	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_16905	COG3757	hydrolase, family 25
HBA75_16935	COG2072	flavoprotein involved in K transport
HBA75_16970	COG1113	amino acid transport
HBA75_16975	COG2814	Major facilitator Superfamily
HBA75_17010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HBA75_17015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBA75_17025	COG1247	-acetyltransferase
HBA75_17030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_17035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_17040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_17045	COG3739	integral membrane protein
HBA75_17065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_17080	COG0583	DNA-binding transcription factor activity
HBA75_17100	COG1193	negative regulation of DNA recombination
HBA75_17110	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HBA75_17115	COG1164	Oligoendopeptidase f
HBA75_17140	COG3781	membrane
HBA75_17155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HBA75_17180	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_17190	COG0640	Transcriptional regulator
HBA75_17195	COG0604	alcohol dehydrogenase
HBA75_17205	COG0457	Tetratricopeptide repeat
HBA75_17220	COG0277	FAD linked oxidase domain protein
HBA75_17245	COG1183	phosphatidylcholine synthase activity
HBA75_17250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_17250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_17255	COG1252	NADH dehydrogenase
HBA75_17265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBA75_17275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBA75_17285	COG0457	Tetratricopeptide repeat
HBA75_17315	COG1309	transcriptional regulator
HBA75_17360	COG3852	Histidine kinase
HBA75_17370	COG1285	pathogenesis
HBA75_17380	COG2514	catechol 2,3-dioxygenase activity
HBA75_17385	COG2720	vancomycin resistance protein
HBA75_17420	COG0716	FMN binding
HBA75_17430	COG0494	nUDIX hydrolase
HBA75_17480	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_17490	COG0165	Argininosuccinate lyase
HBA75_17505	COG4145	pantothenate transmembrane transporter activity
HBA75_17515	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_17520	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_17530	COG1657	PFAM Prenyltransferase squalene oxidase
HBA75_17535	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HBA75_17540	COG2962	Rard protein
HBA75_17550	COG3326	Membrane
HBA75_17565	COG0489	protein tyrosine kinase activity
HBA75_17575	COG0314	molybdopterin synthase activity
HBA75_17580	COG0303	'Molybdopterin
HBA75_17585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_17590	COG2116	formate transmembrane transporter activity
HBA75_17600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBA75_17605	COG5609	conserved protein (DUF2294)
HBA75_17610	COG2427	Protein of unknown function (DUF1641)
HBA75_17615	COG3383	formate dehydrogenase (NAD+) activity
HBA75_17620	COG0697	spore germination
HBA75_17635	COG0531	amino acid
HBA75_17670	COG2226	methyltransferase
HBA75_17675	COG4166	transmembrane transport
HBA75_17680	COG4166	transmembrane transport
HBA75_17685	COG4166	transmembrane transport
HBA75_17690	COG1301	dicarboxylic acid transport
HBA75_17695	COG1316	TRANSCRIPTIONal
HBA75_17705	COG1595	DNA-templated transcription, initiation
HBA75_17720	COG1131	(ABC) transporter
HBA75_17730	COG0673	inositol 2-dehydrogenase activity
HBA75_17735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBA75_17740	COG0187	DNA topoisomerase II activity
HBA75_17745	COG1832	CoA-binding protein
HBA75_17750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBA75_17755	COG0745	RESPONSE REGULATOR receiver
HBA75_17775	COG4841	protein insertion into membrane
HBA75_17785	COG0824	Thioesterase
HBA75_17815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_17825	COG1132	(ABC) transporter
HBA75_17830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBA75_17860	COG2211	Major facilitator Superfamily
HBA75_17870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBA75_17885	COG0183	Belongs to the thiolase family
HBA75_17890	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_17895	COG1268	BioY protein
HBA75_17900	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_17945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_17955	COG5002	protein histidine kinase activity
HBA75_17960	COG0400	carboxylic ester hydrolase activity
HBA75_17965	COG0346	lactoylglutathione lyase activity
HBA75_17970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBA75_17980	COG0069	glutamate synthase activity
HBA75_17990	COG3344	reverse transcriptase
HBA75_18000	COG1329	Transcriptional regulator
HBA75_18005	COG0010	Belongs to the arginase family
HBA75_18055	COG4846	Membrane protein involved in cytochrome C biogenesis
HBA75_18060	COG0785	Cytochrome C biogenesis protein
HBA75_18070	COG1473	amidohydrolase
HBA75_18095	COG0583	DNA-binding transcription factor activity
HBA75_18105	COG1346	cytolysis
HBA75_18120	COG0730	response to heat
HBA75_18145	COG1132	(ABC) transporter
HBA75_18150	COG1132	(ABC) transporter
HBA75_18175	COG3639	organic phosphonate transmembrane transporter activity
HBA75_18200	COG0737	Belongs to the 5'-nucleotidase family
HBA75_18210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HBA75_18230	COG1695	Transcriptional regulator
HBA75_18240	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_18240	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_18240	COG1388	LysM domain
HBA75_18245	COG0739	heme binding
HBA75_18250	COG0741	lytic transglycosylase activity
HBA75_18280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBA75_18285	COG0174	glutamine synthetase
HBA75_18290	COG0789	Transcriptional regulator
HBA75_18295	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HBA75_18300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBA75_18305	COG2860	membrane
HBA75_18315	COG0464	growth
HBA75_18350	COG1388	LysM domain
HBA75_18350	COG3584	3D domain protein
HBA75_18355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_18355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_18355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_18360	COG1105	Belongs to the carbohydrate kinase PfkB family
HBA75_18365	COG1349	DNA-binding transcription factor activity
HBA75_18370	COG1979	alcohol dehydrogenase
HBA75_18375	COG2322	membrane
HBA75_18385	COG1113	amino acid transport
HBA75_18395	COG1408	metallophosphoesterase
HBA75_18400	COG2116	formate transmembrane transporter activity
HBA75_18415	COG2217	Heavy metal translocating P-type atpase
HBA75_18420	COG2608	mercury ion transmembrane transporter activity
HBA75_18425	COG1937	Protein conserved in bacteria
HBA75_18435	COG2819	hydrolase of the alpha beta superfamily
HBA75_18440	COG1120	ATPase activity
HBA75_18445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_18455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_18465	COG2169	Transcriptional regulator
HBA75_18470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBA75_18475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HBA75_18495	COG2267	carboxylic ester hydrolase activity
HBA75_18500	COG3300	MHYT domain
HBA75_18500	COG5001	Diguanylate cyclase
HBA75_18540	COG1346	cytolysis
HBA75_18550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_18560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HBA75_18575	COG1404	Belongs to the peptidase S8 family
HBA75_18580	COG3773	Cell wall hydrolase
HBA75_18590	COG1368	sulfuric ester hydrolase activity
HBA75_18595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HBA75_18620	COG4550	Control of competence regulator ComK, YlbF/YmcA
HBA75_18630	COG1013	pyruvate-flavodoxin oxidoreductase activity
HBA75_18635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HBA75_18635	COG0674	pyruvate-flavodoxin oxidoreductase activity
HBA75_18645	COG2359	stage V sporulation protein S
HBA75_18650	COG1692	metallophosphoesterase
HBA75_18670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBA75_18675	COG1426	Protein conserved in bacteria
HBA75_18690	COG0300	oxidoreductase activity
HBA75_18695	COG0612	Peptidase, M16
HBA75_18700	COG0612	Peptidase, M16
HBA75_18725	COG2188	Transcriptional regulator
HBA75_18745	COG0740	serine-type endopeptidase activity
HBA75_18750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBA75_18760	COG0527	aspartate kinase activity
HBA75_18765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBA75_18770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBA75_18775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBA75_18780	COG1873	PFAM PRC-barrel domain
HBA75_18785	COG0612	Peptidase, M16
HBA75_18790	COG0726	polysaccharide deacetylase
HBA75_18805	COG0196	riboflavin kinase activity
HBA75_18815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HBA75_18820	COG1550	Protein conserved in bacteria
HBA75_18830	COG1358	cellular component organization or biogenesis
HBA75_18835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HBA75_18840	COG0195	Participates in both transcription termination and antitermination
HBA75_18860	COG0750	zinc metalloprotease
HBA75_18870	COG4589	Belongs to the CDS family
HBA75_18915	COG4974	Belongs to the 'phage' integrase family
HBA75_18925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBA75_18930	COG0758	DNA mediated transformation
HBA75_18935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HBA75_18975	COG1837	Belongs to the UPF0109 family
HBA75_18985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBA75_18995	COG0552	protein localization to endoplasmic reticulum
HBA75_19000	COG1196	nuclear chromosome segregation
HBA75_19010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBA75_19015	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_19020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBA75_19035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBA75_19040	COG1461	Dihydroxyacetone kinase
HBA75_19045	COG1302	Protein conserved in bacteria
HBA75_19060	COG1564	THIamine pyrophosphokinase
HBA75_19065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBA75_19075	COG2815	serine threonine protein kinase
HBA75_19075	COG0515	serine threonine protein kinase
HBA75_19080	COG0631	protein serine/threonine phosphatase activity
HBA75_19090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HBA75_19090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HBA75_19105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBA75_19110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBA75_19130	COG1561	YicC-like family, N-terminal region
HBA75_19135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBA75_19145	COG0006	proline dipeptidase activity
HBA75_19160	COG3069	C4-dicarboxylate transmembrane transporter activity
HBA75_19220	COG0564	pseudouridine synthase activity
HBA75_19240	COG3599	regulation of cell shape
HBA75_19245	COG2302	S4 RNA-binding domain
HBA75_19250	COG0762	integral membrane protein
HBA75_19260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HBA75_19270	COG1873	PFAM PRC-barrel domain
HBA75_19275	COG1191	sigma factor activity
HBA75_19280	COG1191	sigma factor activity
HBA75_19290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBA75_19295	COG0849	cell division
HBA75_19315	COG0772	Belongs to the SEDS family
HBA75_19335	COG0768	penicillin binding
HBA75_19360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBA75_19375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HBA75_19380	COG1399	metal-binding, possibly nucleic acid-binding protein
HBA75_19390	COG3480	Lon protease (S16) C-terminal proteolytic domain
HBA75_19395	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBA75_19400	COG3314	Sporulation integral membrane protein YlbJ
HBA75_19410	COG0742	ribosomal rna small subunit methyltransferase
HBA75_19425	COG3679	Belongs to the UPF0342 family
HBA75_19430	COG0406	alpha-ribazole phosphatase activity
HBA75_19445	COG2340	Cysteine-rich secretory protein family
HBA75_19460	COG3336	cytochrome c oxidase
HBA75_19495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HBA75_19500	COG0772	Belongs to the SEDS family
HBA75_19510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HBA75_19515	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HBA75_19525	COG4896	Protein conserved in bacteria
HBA75_19550	COG0483	inositol monophosphate 1-phosphatase activity
HBA75_19570	COG1982	Orn Lys Arg decarboxylase major
HBA75_19620	COG0022	dehydrogenase e1 component
HBA75_19625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBA75_19640	COG0561	phosphatase activity
HBA75_19650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBA75_19655	COG0569	domain protein
HBA75_19675	COG0583	DNA-binding transcription factor activity
HBA75_19680	COG0517	IMP dehydrogenase activity
HBA75_19690	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HBA75_19700	COG4703	Protein of unknown function (DUF1797)
HBA75_19715	COG2200	EAL domain
HBA75_19720	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_19725	COG1408	metallophosphoesterase
HBA75_19770	COG2814	Major facilitator Superfamily
HBA75_19790	COG3209	COG3209 Rhs family protein
HBA75_19800	COG2205	protein histidine kinase activity
HBA75_19810	COG0436	Aminotransferase
HBA75_19815	COG1609	Transcriptional regulator
HBA75_19820	COG3833	ABC-type maltose transport systems, permease component
HBA75_19825	COG1175	transmembrane transport
HBA75_19830	COG2182	Extracellular solute-binding protein
HBA75_19840	COG0366	Alpha amylase catalytic
HBA75_19845	COG3842	ATPase activity
HBA75_19890	COG0183	Belongs to the thiolase family
HBA75_19925	COG1695	Transcriptional regulator
HBA75_19930	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_19960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBA75_19965	COG0436	Aminotransferase
HBA75_20000	COG2084	Dehydrogenase
HBA75_20010	COG2203	Gaf domain
HBA75_20010	COG2199	diguanylate cyclase activity
HBA75_20015	COG0778	Nitroreductase
HBA75_20040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_20040	COG1263	PTS System
HBA75_20040	COG2190	(PTS) system
HBA75_20045	COG3711	transcriptional antiterminator
HBA75_20055	COG2188	Transcriptional regulator
HBA75_20065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HBA75_20090	COG1547	Domain of unknown function (DUF309)
HBA75_20095	COG0456	acetyltransferase
HBA75_20100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBA75_20105	COG4086	secreted protein
HBA75_20110	COG2801	Transposase and inactivated derivatives
HBA75_20120	COG0561	phosphatase activity
HBA75_20125	COG0697	spore germination
HBA75_20175	COG0733	neurotransmitter:sodium symporter activity
HBA75_20195	COG1686	Belongs to the peptidase S11 family
HBA75_20200	COG1725	Transcriptional regulator
HBA75_20205	COG1131	(ABC) transporter
HBA75_20225	COG1846	Transcriptional regulator
HBA75_20240	COG0598	Magnesium transport protein CorA
HBA75_20265	COG4974	Belongs to the 'phage' integrase family
HBA75_20275	COG0735	belongs to the Fur family
HBA75_20280	COG1300	Membrane
HBA75_20300	COG0667	Aldo Keto reductase
HBA75_20305	COG0656	L-ascorbic acid biosynthetic process
HBA75_20310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBA75_20310	COG0456	acetyltransferase
HBA75_20320	COG4085	toxin activity
HBA75_20320	COG1525	nuclease
HBA75_20320	COG0737	Belongs to the 5'-nucleotidase family
HBA75_20330	COG0596	Alpha beta hydrolase
HBA75_20335	COG2056	Na+-H+ antiporter family
HBA75_20340	COG1609	Transcriptional regulator
HBA75_20345	COG0456	acetyltransferase
HBA75_20350	COG1073	alpha beta
HBA75_20365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_20365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBA75_20370	COG0307	riboflavin synthase, alpha
HBA75_20400	COG1073	alpha beta
HBA75_20400	COG2226	methyltransferase
HBA75_20415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HBA75_20430	COG0737	Belongs to the 5'-nucleotidase family
HBA75_20440	COG1522	sequence-specific DNA binding
HBA75_20485	COG0300	oxidoreductase activity
HBA75_20490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_20495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_20500	COG1760	l-serine dehydratase
HBA75_20505	COG1760	l-serine dehydratase
HBA75_20550	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBA75_20555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_20570	COG1376	ErfK ybiS ycfS ynhG family protein
HBA75_20575	COG4129	membrane
HBA75_20580	COG1126	abc transporter atp-binding protein
HBA75_20585	COG0765	amino acid transport
HBA75_20590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBA75_20605	COG2816	NAD+ diphosphatase activity
HBA75_20610	COG2323	membrane
HBA75_20615	COG0772	Belongs to the SEDS family
HBA75_20620	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBA75_20625	COG0022	dehydrogenase e1 component
HBA75_20630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBA75_20635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBA75_20650	COG0280	phosphate acetyltransferase
HBA75_20655	COG3829	transcription factor binding
HBA75_20655	COG3290	protein histidine kinase activity
HBA75_20665	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_20670	COG3093	addiction module antidote protein HigA
HBA75_20690	COG0750	zinc metalloprotease
HBA75_20695	COG0497	DNA recombination
HBA75_20720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HBA75_20730	COG0142	geranyltranstransferase activity
HBA75_20755	COG1302	Protein conserved in bacteria
HBA75_20760	COG0439	Biotin carboxylase
HBA75_20765	COG0511	ligase activity, forming carbon-carbon bonds
HBA75_20810	COG3854	ATPases associated with a variety of cellular activities
HBA75_20835	COG0006	proline dipeptidase activity
HBA75_20855	COG3872	metal-dependent enzyme
HBA75_20865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBA75_20880	COG1695	Transcriptional regulator
HBA75_20900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_20910	COG1609	Transcriptional regulator
HBA75_20920	COG2076	Multidrug Resistance protein
HBA75_20925	COG2076	Multidrug Resistance protein
HBA75_20960	COG1725	Transcriptional regulator
HBA75_20990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HBA75_21055	COG1459	type II secretion system
HBA75_21060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HBA75_21115	COG0646	methionine synthase
HBA75_21115	COG1410	methionine synthase
HBA75_21120	COG0646	methionine synthase
HBA75_21120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HBA75_21125	COG0626	cystathionine gamma-synthase activity
HBA75_21130	COG0626	cystathionine gamma-synthase activity
HBA75_21155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_21165	COG1940	carbohydrate kinase activity
HBA75_21170	COG4483	Protein conserved in bacteria
HBA75_21175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBA75_21180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HBA75_21185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBA75_21190	COG0704	Plays a role in the regulation of phosphate uptake
HBA75_21200	COG0573	inorganic phosphate transmembrane transporter activity
HBA75_21205	COG0573	inorganic phosphate transmembrane transporter activity
HBA75_21210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBA75_21220	COG0477	Major facilitator Superfamily
HBA75_21225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBA75_21235	COG5521	maltodextrose utilization protein MalA
HBA75_21250	COG0735	belongs to the Fur family
HBA75_21255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBA75_21260	COG1121	(ABC) transporter
HBA75_21265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_21295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBA75_21300	COG2384	SAM-dependent methyltransferase
HBA75_21310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HBA75_21315	COG0358	DNA primase activity
HBA75_21330	COG0517	IMP dehydrogenase activity
HBA75_21345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBA75_21350	COG0295	cytidine deaminase activity
HBA75_21355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HBA75_21365	COG1480	7TM receptor with intracellular HD hydrolase
HBA75_21370	COG1702	phosphate starvation-inducible protein PhoH
HBA75_21390	COG1610	YqeY-like protein
HBA75_21395	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HBA75_21400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HBA75_21405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBA75_21435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBA75_21440	COG1733	regulation of RNA biosynthetic process
HBA75_21450	COG2801	Transposase and inactivated derivatives
HBA75_21475	COG1466	dna polymerase III delta subunit
HBA75_21490	COG2131	deaminase
HBA75_21495	COG1596	polysaccharide export
HBA75_21495	COG1555	photosystem II stabilization
HBA75_21500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBA75_21505	COG2226	methyltransferase
HBA75_21510	COG0799	negative regulation of ribosome biogenesis
HBA75_21515	COG1713	HD superfamily hydrolase involved in NAD metabolism
HBA75_21525	COG1534	Rna-binding protein
HBA75_21535	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HBA75_21540	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HBA75_21575	COG0778	Nitroreductase
HBA75_21580	COG2357	RelA SpoT domain protein
HBA75_21590	COG1785	Belongs to the alkaline phosphatase family
HBA75_21600	COG2267	carboxylic ester hydrolase activity
HBA75_21635	COG1404	Belongs to the peptidase S8 family
HBA75_21650	COG2514	catechol 2,3-dioxygenase activity
HBA75_21655	COG2259	Doxx family
HBA75_21695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_21705	COG1012	belongs to the aldehyde dehydrogenase family
HBA75_21705	COG1454	alcohol dehydrogenase
HBA75_21710	COG0626	cystathionine gamma-synthase activity
HBA75_21715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBA75_21770	COG4122	O-methyltransferase activity
HBA75_21775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBA75_21805	COG0628	permease
HBA75_21825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBA75_21840	COG1104	cysteine desulfurase activity
HBA75_21845	COG1959	2 iron, 2 sulfur cluster binding
HBA75_21850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBA75_21860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBA75_21885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBA75_21895	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HBA75_21895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBA75_21900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBA75_21905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBA75_21905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBA75_21915	COG2244	polysaccharide biosynthetic process
HBA75_21920	COG2323	membrane
HBA75_21935	COG1862	Preprotein translocase
HBA75_21965	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HBA75_22000	COG0157	Belongs to the NadC ModD family
HBA75_22005	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HBA75_22010	COG1104	cysteine desulfurase activity
HBA75_22015	COG1827	regulation of RNA biosynthetic process
HBA75_22020	COG2258	MOSC domain
HBA75_22025	COG0077	Prephenate dehydratase
HBA75_22030	COG0577	efflux transmembrane transporter activity
HBA75_22035	COG0577	efflux transmembrane transporter activity
HBA75_22040	COG1136	(ABC) transporter
HBA75_22045	COG5002	protein histidine kinase activity
HBA75_22050	COG0745	RESPONSE REGULATOR receiver
HBA75_22060	COG3290	protein histidine kinase activity
HBA75_22070	COG2868	ribosomal protein
HBA75_22080	COG1530	ribonuclease E activity
HBA75_22085	COG1994	Peptidase M50
HBA75_22090	COG0739	heme binding
HBA75_22095	COG2894	cell division
HBA75_22115	COG1077	Cell shape determining protein MreB Mrl
HBA75_22145	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_22145	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_22145	COG1388	LysM domain
HBA75_22150	COG4824	toxin secretion phage lysis holin
HBA75_22270	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_22285	COG1595	DNA-templated transcription, initiation
HBA75_22295	COG3331	DNA recombination
HBA75_22390	COG3646	Phage regulatory protein
HBA75_22410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HBA75_22430	COG0285	dihydrofolate synthase activity
HBA75_22445	COG1388	LysM domain
HBA75_22455	COG0113	porphobilinogen synthase activity
HBA75_22460	COG1587	Uroporphyrinogen-III synthase
HBA75_22470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HBA75_22480	COG1846	Transcriptional regulator
HBA75_22490	COG1764	response to oxidative stress
HBA75_22505	COG0470	DNA polymerase III
HBA75_22505	COG1067	ATP-dependent peptidase activity
HBA75_22550	COG0622	Phosphoesterase
HBA75_22565	COG5401	PFAM Sporulation and spore germination
HBA75_22585	COG1309	transcriptional regulator
HBA75_22595	COG2197	response regulator
HBA75_22600	COG2233	PERMEase
HBA75_22605	COG0402	S-adenosylhomocysteine deaminase activity
HBA75_22610	COG1983	PspC domain protein
HBA75_22615	COG1396	sequence-specific DNA binding
HBA75_22620	COG0697	spore germination
HBA75_22630	COG1959	2 iron, 2 sulfur cluster binding
HBA75_22635	COG1668	transmembrane transport
HBA75_22640	COG4152	abc transporter atp-binding protein
HBA75_22645	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HBA75_22650	COG1360	Flagellar Motor Protein
HBA75_22655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HBA75_22660	COG1876	peptidase activity
HBA75_22665	COG0824	Thioesterase
HBA75_22670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBA75_22675	COG1053	succinate dehydrogenase
HBA75_22680	COG2009	succinate dehydrogenase
HBA75_22685	COG1719	4-vinyl reductase, 4VR
HBA75_22695	COG3118	belongs to the thioredoxin family
HBA75_22700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HBA75_22705	COG2086	electron transfer activity
HBA75_22710	COG1024	Enoyl-CoA hydratase
HBA75_22715	COG1309	transcriptional regulator
HBA75_22720	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_22750	COG2318	DinB family
HBA75_22775	COG1131	(ABC) transporter
HBA75_22780	COG2205	protein histidine kinase activity
HBA75_22785	COG0745	RESPONSE REGULATOR receiver
HBA75_22795	COG4895	conserved protein (DUF2196)
HBA75_22800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HBA75_22810	COG4509	Sortase family
HBA75_22815	COG1120	ATPase activity
HBA75_22830	COG5386	Cell surface protein
HBA75_22840	COG5386	Cell surface protein
HBA75_22845	COG1114	Component of the transport system for branched-chain amino acids
HBA75_22850	COG1187	pseudouridine synthase activity
HBA75_22860	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HBA75_22860	COG1796	DNA polymerase
HBA75_22865	COG1286	toxin biosynthetic process
HBA75_22905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBA75_22915	COG1418	mRNA catabolic process
HBA75_22930	COG2814	Major facilitator Superfamily
HBA75_22935	COG1566	PFAM secretion protein HlyD family protein
HBA75_22940	COG1309	transcriptional regulator
HBA75_22945	COG1363	Peptidase, m42
HBA75_22970	COG2801	Transposase and inactivated derivatives
HBA75_22980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBA75_22995	COG1484	DNA-dependent DNA replication
HBA75_23000	COG3611	Membrane attachment protein
HBA75_23010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HBA75_23015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBA75_23025	COG1971	Probably functions as a manganese efflux pump
HBA75_23035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBA75_23035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBA75_23040	COG5002	protein histidine kinase activity
HBA75_23045	COG0745	RESPONSE REGULATOR receiver
HBA75_23060	COG0538	isocitrate dehydrogenase activity
HBA75_23065	COG0372	Belongs to the citrate synthase family
HBA75_23075	COG0628	permease
HBA75_23080	COG3030	protein affecting phage T7 exclusion by the F plasmid
HBA75_23105	COG1725	Transcriptional regulator
HBA75_23110	COG0281	malic enzyme
HBA75_23115	COG0587	DNA-directed DNA polymerase activity
HBA75_23130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HBA75_23145	COG4109	DRTGG domain
HBA75_23160	COG0006	proline dipeptidase activity
HBA75_23185	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_23195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_23200	COG0662	Cupin 2, conserved barrel domain protein
HBA75_23215	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_23220	COG0589	response to stress
HBA75_23260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_23285	COG0827	DNA restriction-modification system
HBA75_23290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBA75_23295	COG3874	Sporulation protein YtfJ
HBA75_23310	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HBA75_23320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBA75_23335	COG1104	cysteine desulfurase activity
HBA75_23360	COG0697	spore germination
HBA75_23365	COG1309	transcriptional regulator
HBA75_23370	COG1956	GAF domain-containing protein
HBA75_23375	COG0626	cystathionine gamma-synthase activity
HBA75_23405	COG0110	maltose O-acetyltransferase activity
HBA75_23410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBA75_23415	COG0454	-acetyltransferase
HBA75_23420	COG0517	IMP dehydrogenase activity
HBA75_23425	COG0123	including yeast histone deacetylase and acetoin utilization protein
HBA75_23440	COG0745	RESPONSE REGULATOR receiver
HBA75_23450	COG0666	response to abiotic stimulus
HBA75_23485	COG1609	Transcriptional regulator
HBA75_23490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HBA75_23490	COG1605	Chorismate mutase
HBA75_23495	COG4851	CamS sex pheromone cAM373 precursor
HBA75_23500	COG3118	belongs to the thioredoxin family
HBA75_23510	COG2309	aminopeptidase activity
HBA75_23525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_23540	COG1674	ftsk spoiiie
HBA75_23545	COG0860	N-Acetylmuramoyl-L-alanine amidase
HBA75_23545	COG1388	LysM domain
HBA75_23555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBA75_23565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_23570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HBA75_23575	COG1363	Peptidase, m42
HBA75_23585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_23605	COG0510	thiamine kinase activity
HBA75_23615	COG1523	belongs to the glycosyl hydrolase 13 family
HBA75_23625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HBA75_23630	COG1349	DNA-binding transcription factor activity
HBA75_23635	COG1187	pseudouridine synthase activity
HBA75_23640	COG2244	polysaccharide biosynthetic process
HBA75_23645	COG2081	HI0933 family
HBA75_23670	COG3832	glyoxalase III activity
HBA75_23690	COG1329	Transcriptional regulator
HBA75_23715	COG0314	molybdopterin synthase activity
HBA75_23720	COG1763	Mo-molybdopterin cofactor biosynthetic process
HBA75_23725	COG0303	'Molybdopterin
HBA75_23735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HBA75_23740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBA75_23765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBA75_23775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBA75_23825	COG0475	glutathione-regulated potassium exporter activity
HBA75_23830	COG0490	domain, Protein
HBA75_23835	COG0582	viral genome integration into host DNA
HBA75_23845	COG1136	(ABC) transporter
HBA75_23865	COG1242	4 iron, 4 sulfur cluster binding
HBA75_23870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HBA75_23875	COG1794	racemase activity, acting on amino acids and derivatives
HBA75_23890	COG2267	carboxylic ester hydrolase activity
HBA75_23895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBA75_23900	COG0671	phosphoesterase, PA-phosphatase related
HBA75_23905	COG0438	transferase activity, transferring glycosyl groups
HBA75_23925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_23970	COG5002	protein histidine kinase activity
HBA75_23975	COG3852	Histidine kinase
HBA75_23990	COG2267	carboxylic ester hydrolase activity
HBA75_23995	COG1368	sulfuric ester hydrolase activity
HBA75_24020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_24025	COG1116	anion transmembrane transporter activity
HBA75_24030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_24055	COG2801	Transposase and inactivated derivatives
HBA75_24070	COG0494	nUDIX hydrolase
HBA75_24100	COG1854	S-ribosylhomocysteine lyase activity
HBA75_24110	COG0288	reversible hydration of carbon dioxide
HBA75_24115	COG1271	oxidase subunit
HBA75_24120	COG1294	oxidase, subunit
HBA75_24135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_24160	COG1842	Phage shock protein A
HBA75_24190	COG5002	protein histidine kinase activity
HBA75_24195	COG0745	RESPONSE REGULATOR receiver
HBA75_24225	COG1597	lipid kinase activity
HBA75_24245	COG3344	reverse transcriptase
HBA75_24290	COG0586	Pfam SNARE associated Golgi protein
HBA75_24300	COG0577	efflux transmembrane transporter activity
HBA75_24305	COG1136	(ABC) transporter
HBA75_24310	COG3708	Transcriptional regulator
HBA75_24310	COG2207	Transcriptional regulator
HBA75_24330	COG5658	integral membrane protein
HBA75_24335	COG0640	Transcriptional regulator
HBA75_24340	COG0745	RESPONSE REGULATOR receiver
HBA75_24345	COG2205	protein histidine kinase activity
HBA75_24350	COG0577	efflux transmembrane transporter activity
HBA75_24355	COG0577	efflux transmembrane transporter activity
HBA75_24360	COG1136	(ABC) transporter
HBA75_24365	COG0577	efflux transmembrane transporter activity
HBA75_24390	COG2188	Transcriptional regulator
HBA75_24410	COG3964	amidohydrolase
HBA75_24430	COG4948	Mandelate Racemase Muconate Lactonizing
HBA75_24440	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HBA75_24445	COG0596	Alpha beta hydrolase
HBA75_24455	COG1169	isochorismate synthase
HBA75_24460	COG1575	Belongs to the MenA family. Type 1 subfamily
HBA75_24465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBA75_24490	COG0058	SHG alpha-glucan phosphorylase activity
HBA75_24500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HBA75_24520	COG1404	Belongs to the peptidase S8 family
HBA75_24620	COG0544	peptidyl-prolyl cis-trans isomerase activity
HBA75_24655	COG1285	pathogenesis
HBA75_24660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBA75_24675	COG2155	Conserved Protein
HBA75_24680	COG1098	S1 RNA binding domain
HBA75_24685	COG0436	Aminotransferase
HBA75_24690	COG1522	sequence-specific DNA binding
HBA75_24695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBA75_24700	COG2267	carboxylic ester hydrolase activity
HBA75_24710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HBA75_24730	COG5018	Exonuclease
HBA75_24735	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBA75_24755	COG2050	protein possibly involved in aromatic compounds catabolism
HBA75_24765	COG1268	BioY protein
HBA75_24770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBA75_24775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBA75_24795	COG2076	Multidrug Resistance protein
HBA75_24800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HBA75_24810	COG3584	3D domain protein
HBA75_24825	COG1252	NADH dehydrogenase
HBA75_24840	COG3708	Transcriptional regulator
HBA75_24855	COG1683	Conserved Protein
HBA75_24910	COG4824	toxin secretion phage lysis holin
HBA75_25050	COG1191	sigma factor activity
HBA75_25075	COG3645	SOS response
HBA75_25075	COG3646	Phage regulatory protein
HBA75_25095	COG1396	sequence-specific DNA binding
HBA75_25135	COG0316	Belongs to the HesB IscA family
HBA75_25150	COG1252	NADH dehydrogenase
HBA75_25160	COG2274	protein secretion by the type I secretion system
HBA75_25165	COG0390	transport system, permease component
HBA75_25170	COG2824	Alkylphosphonate utilization operon protein PhnA
HBA75_25215	COG3344	reverse transcriptase
HBA75_25245	COG4837	Protein of unknown function (DUF1462)
HBA75_25250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HBA75_25260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBA75_25265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBA75_25285	COG1358	cellular component organization or biogenesis
HBA75_25295	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBA75_25305	COG0647	UMP catabolic process
HBA75_25315	COG2445	Protein of unknown function DUF86
HBA75_25320	COG1494	fructose-1,6-bisphosphatase
HBA75_25340	COG4470	Protein conserved in bacteria
HBA75_25350	COG0789	Transcriptional regulator
HBA75_25355	COG4377	Putative membrane peptidase family (DUF2324)
HBA75_25380	COG0739	heme binding
HBA75_25390	COG3377	Domain of unknown function (DUF1805)
HBA75_25395	COG0737	Belongs to the 5'-nucleotidase family
HBA75_25400	COG0719	Fe-S assembly protein
HBA75_25405	COG0822	iron-sulfur transferase activity
HBA75_25410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBA75_25415	COG0719	Fe-S assembly protein
HBA75_25420	COG0396	ATPase activity
HBA75_25425	COG1464	Belongs to the NlpA lipoprotein family
HBA75_25430	COG1464	Belongs to the NlpA lipoprotein family
HBA75_25435	COG2011	ABC-type metal ion transport system permease component
HBA75_25450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HBA75_25455	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HBA75_25465	COG1393	Belongs to the ArsC family
HBA75_25505	COG1309	transcriptional regulator
HBA75_25510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBA75_25515	COG1960	acyl-CoA dehydrogenase activity
HBA75_25520	COG0183	Belongs to the thiolase family
HBA75_25525	COG1024	Enoyl-CoA hydratase
HBA75_25525	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBA75_25535	COG1686	Belongs to the peptidase S11 family
HBA75_25550	COG0011	TIGRFAM Protein of
HBA75_25555	COG0840	transmembrane signaling receptor activity
HBA75_25570	COG2814	Major facilitator Superfamily
HBA75_25575	COG0531	amino acid
HBA75_25600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HBA75_25635	COG0586	Pfam SNARE associated Golgi protein
HBA75_25645	COG1376	ErfK ybiS ycfS ynhG family protein
HBA75_25650	COG0745	RESPONSE REGULATOR receiver
HBA75_25655	COG5002	protein histidine kinase activity
HBA75_25705	COG0840	transmembrane signaling receptor activity
HBA75_25710	COG2151	metal-sulfur cluster biosynthetic enzyme
HBA75_25715	COG3227	Zinc metalloprotease (Elastase)
HBA75_25735	COG0586	Pfam SNARE associated Golgi protein
HBA75_25740	COG0475	glutathione-regulated potassium exporter activity
HBA75_25745	COG0490	domain, Protein
HBA75_25755	COG1115	amino acid carrier protein
HBA75_25760	COG0783	Belongs to the Dps family
HBA75_25775	COG1611	Belongs to the LOG family
HBA75_25785	COG1528	Iron-storage protein
HBA75_25795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_25800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_25805	COG1115	amino acid carrier protein
HBA75_25810	COG1115	amino acid carrier protein
HBA75_25815	COG2910	NAD(P)H-binding
HBA75_25830	COG0656	L-ascorbic acid biosynthetic process
HBA75_25835	COG2814	Major facilitator Superfamily
HBA75_25840	COG1733	regulation of RNA biosynthetic process
HBA75_25850	COG1252	NADH dehydrogenase
HBA75_25900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HBA75_25915	COG1335	isochorismatase
HBA75_25920	COG1522	sequence-specific DNA binding
HBA75_25985	COG0557	exoribonuclease II activity
HBA75_25990	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_26015	COG1674	ftsk spoiiie
HBA75_26040	COG4824	toxin secretion phage lysis holin
HBA75_26050	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_26125	COG5484	DNA packaging
HBA75_26150	COG0582	viral genome integration into host DNA
HBA75_26250	COG3646	Phage regulatory protein
HBA75_26270	COG1396	sequence-specific DNA binding
HBA75_26280	COG0582	viral genome integration into host DNA
HBA75_26285	COG1647	Serine aminopeptidase, S33
HBA75_26290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HBA75_26295	COG1346	cytolysis
HBA75_26330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBA75_26345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HBA75_26370	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_26370	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_26370	COG1388	LysM domain
HBA75_26375	COG4824	toxin secretion phage lysis holin
HBA75_26450	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_26510	COG1595	DNA-templated transcription, initiation
HBA75_26520	COG3331	DNA recombination
HBA75_26625	COG3646	Phage regulatory protein
HBA75_26655	COG0582	viral genome integration into host DNA
HBA75_26705	COG0582	viral genome integration into host DNA
HBA75_26710	COG1555	photosystem II stabilization
HBA75_26710	COG1596	polysaccharide export
HBA75_26740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBA75_26755	COG2323	membrane
HBA75_26765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_26775	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HBA75_26785	COG1051	belongs to the nudix hydrolase family
HBA75_26795	COG0492	ferredoxin-NADP+ reductase activity
HBA75_26800	COG0457	Tetratricopeptide repeat
HBA75_26805	COG0110	maltose O-acetyltransferase activity
HBA75_26825	COG1950	PFAM Membrane protein of
HBA75_26835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBA75_26840	COG0556	nucleotide-excision repair
HBA75_26855	COG0789	Transcriptional regulator
HBA75_26875	COG0583	DNA-binding transcription factor activity
HBA75_26885	COG0655	NAD(P)H dehydrogenase (quinone) activity
HBA75_26890	COG0488	(ABC) transporter
HBA75_26900	COG1132	(ABC) transporter
HBA75_26905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBA75_26910	COG0793	Belongs to the peptidase S41A family
HBA75_26910	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_26915	COG2177	Part of the ABC transporter FtsEX involved in
HBA75_26920	COG2884	Cell division ATP-binding protein ftsE
HBA75_26940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBA75_26945	COG1278	Cold shock
HBA75_26950	COG1040	competence protein
HBA75_26955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HBA75_26960	COG0791	NLP P60 protein
HBA75_26960	COG3103	Sh3 type 3 domain protein
HBA75_26960	COG1388	LysM domain
HBA75_26965	COG1733	regulation of RNA biosynthetic process
HBA75_26970	COG1307	EDD domain protein, DegV family
HBA75_26975	COG1739	Uncharacterized protein family UPF0029
HBA75_26980	COG1316	TRANSCRIPTIONal
HBA75_26985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBA75_26990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBA75_26995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBA75_27005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HBA75_27005	COG3933	PFAM sigma-54 factor interaction domain-containing protein
HBA75_27025	COG1486	melibiose metabolic process
HBA75_27030	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBA75_27035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBA75_27055	COG1447	Phosphotransferase system cellobiose-specific component IIA
HBA75_27065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HBA75_27070	COG1301	dicarboxylic acid transport
HBA75_27085	COG1511	domain protein
HBA75_27090	COG0583	DNA-binding transcription factor activity
HBA75_27095	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HBA75_27105	COG1271	oxidase subunit
HBA75_27110	COG1294	oxidase, subunit
HBA75_27115	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HBA75_27125	COG1620	l-lactate permease
HBA75_27135	COG2389	metal-binding protein
HBA75_27145	COG1368	sulfuric ester hydrolase activity
HBA75_27155	COG1388	LysM domain
HBA75_27155	COG0791	NLP P60 protein
HBA75_27160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HBA75_27185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBA75_27190	COG1388	LysM domain
HBA75_27190	COG3584	3D domain protein
HBA75_27225	COG4715	Zinc finger, swim domain protein
HBA75_27230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HBA75_27240	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_27275	COG0577	efflux transmembrane transporter activity
HBA75_27280	COG1136	(ABC) transporter
HBA75_27315	COG5002	protein histidine kinase activity
HBA75_27320	COG0745	RESPONSE REGULATOR receiver
HBA75_27325	COG1482	cell wall glycoprotein biosynthetic process
HBA75_27330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_27330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_27330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBA75_27335	COG3711	transcriptional antiterminator
HBA75_27335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBA75_27340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBA75_27355	COG1482	cell wall glycoprotein biosynthetic process
HBA75_27385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HBA75_27390	COG1091	dTDP-4-dehydrorhamnose reductase activity
HBA75_27405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBA75_27430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HBA75_27435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBA75_27440	COG4464	protein tyrosine phosphatase activity
HBA75_27445	COG0489	protein tyrosine kinase activity
HBA75_27450	COG3944	biosynthesis protein
HBA75_27455	COG0489	protein tyrosine kinase activity
HBA75_27470	COG1609	Transcriptional regulator
HBA75_27480	COG0739	heme binding
HBA75_27495	COG3279	Response regulator of the LytR AlgR family
HBA75_27500	COG2385	sporulation resulting in formation of a cellular spore
HBA75_27515	COG4836	Membrane
HBA75_27520	COG1007	ATP synthesis coupled electron transport
HBA75_27525	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBA75_27530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBA75_27540	COG0839	Belongs to the complex I subunit 6 family
HBA75_27560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBA75_27575	COG5001	Diguanylate cyclase
HBA75_27575	COG3300	MHYT domain
HBA75_27625	COG0356	it plays a direct role in the translocation of protons across the membrane
HBA75_27660	COG0698	ribose 5-phosphate isomerase
HBA75_27675	COG2259	Doxx family
HBA75_27680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBA75_27695	COG0009	L-threonylcarbamoyladenylate synthase
HBA75_27730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HBA75_27735	COG1494	fructose-1,6-bisphosphatase
HBA75_27755	COG4821	SIS domain
HBA75_27765	COG3343	RNA polymerase activity
HBA75_27775	COG1960	acyl-CoA dehydrogenase activity
HBA75_27780	COG1960	acyl-CoA dehydrogenase activity
HBA75_27785	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBA75_27790	COG0183	Belongs to the thiolase family
HBA75_27795	COG2181	nitrate reductase activity
HBA75_27795	COG0247	lactate metabolic process
HBA75_27800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBA75_27815	COG3300	MHYT domain
HBA75_27815	COG5001	Diguanylate cyclase
HBA75_27830	COG3227	Zinc metalloprotease (Elastase)
HBA75_27835	COG2197	response regulator
HBA75_27840	COG4585	Histidine kinase
HBA75_27845	COG0842	Transport permease protein
HBA75_27850	COG1131	(ABC) transporter
HBA75_27855	COG0024	Methionine aminopeptidase
HBA75_27865	COG2234	aminopeptidase activity
HBA75_27880	COG1595	DNA-templated transcription, initiation
HBA75_27890	COG4506	Protein conserved in bacteria
HBA75_27895	COG1619	proteins homologs of microcin C7 resistance protein MccF
HBA75_27920	COG2814	Major facilitator Superfamily
HBA75_27925	COG0789	Transcriptional regulator
HBA75_27930	COG0584	glycerophosphoryl diester phosphodiesterase
HBA75_27935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBA75_27945	COG1994	Peptidase M50
HBA75_27955	COG1078	dGTPase activity
HBA75_27960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_27965	COG1120	ATPase activity
HBA75_27970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_27975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_27995	COG0280	phosphate acetyltransferase
HBA75_28010	COG3773	Cell wall hydrolase
HBA75_28035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBA75_28040	COG2233	PERMEase
HBA75_28045	COG0561	phosphatase activity
HBA75_28050	COG2814	Major facilitator Superfamily
HBA75_28060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HBA75_28065	COG1131	(ABC) transporter
HBA75_28070	COG2755	lipolytic protein G-D-S-L family
HBA75_28075	COG1609	Transcriptional regulator
HBA75_28085	COG0460	homoserine dehydrogenase
HBA75_28095	COG2873	o-acetylhomoserine
HBA75_28105	COG1011	Hydrolase
HBA75_28110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_28120	COG2197	response regulator
HBA75_28125	COG4585	Histidine kinase
HBA75_28125	COG2203	Gaf domain
HBA75_28130	COG0351	phosphomethylpyrimidine kinase
HBA75_28135	COG3706	GGDEF domain
HBA75_28140	COG2879	small protein
HBA75_28145	COG1966	Carbon starvation protein
HBA75_28150	COG3279	Response regulator of the LytR AlgR family
HBA75_28155	COG0477	Major facilitator Superfamily
HBA75_28160	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HBA75_28165	COG0438	transferase activity, transferring glycosyl groups
HBA75_28180	COG0840	transmembrane signaling receptor activity
HBA75_28190	COG1607	acyl-coa hydrolase
HBA75_28195	COG1216	Glycosyl transferase, family 2
HBA75_28205	COG1216	Glycosyl transferase, family 2
HBA75_28225	COG0463	Glycosyl transferase, family 2
HBA75_28230	COG0488	(ABC) transporter
HBA75_28235	COG1309	transcriptional regulator
HBA75_28240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBA75_28245	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBA75_28245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBA75_28250	COG0628	permease
HBA75_28270	COG3275	phosphorelay sensor kinase activity
HBA75_28275	COG2814	Major facilitator Superfamily
HBA75_28280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBA75_28285	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HBA75_28305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBA75_28310	COG1272	protein, Hemolysin III
HBA75_28330	COG1164	Oligoendopeptidase f
HBA75_28350	COG2801	Transposase and inactivated derivatives
HBA75_28365	COG5002	protein histidine kinase activity
HBA75_28380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBA75_28385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HBA75_28390	COG4853	Protein conserved in bacteria
HBA75_28400	COG5002	protein histidine kinase activity
HBA75_28405	COG0745	RESPONSE REGULATOR receiver
HBA75_28435	COG0305	Participates in initiation and elongation during chromosome replication
HBA75_28445	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HBA75_28450	COG4241	membrane
HBA75_28470	COG0012	GTP binding
HBA75_28475	COG4481	Protein conserved in bacteria
HBA75_28480	COG0668	transmembrane transport
HBA75_28490	COG1475	DNA binding
HBA75_28495	COG1192	Involved in chromosome partitioning
HBA75_28520	COG1847	R3H domain protein
HBA75_28535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HBA75_28540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_28540	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_28540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_28540	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_28540	COG0300	oxidoreductase activity
HBA75_28540	COG3321	synthase
HBA75_28540	COG3321	synthase
HBA75_28540	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_28540	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_28540	COG0300	oxidoreductase activity
HBA75_28560	COG1960	acyl-CoA dehydrogenase activity
HBA75_28575	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBA75_28580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBA75_28585	COG1960	acyl-CoA dehydrogenase activity
HBA75_28595	COG1028	Short-chain dehydrogenase reductase Sdr
HBA75_28595	COG0300	oxidoreductase activity
HBA75_28595	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_28595	COG3321	synthase
HBA75_28595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBA75_28600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBA75_28635	COG1609	Transcriptional regulator
HBA75_28650	COG0561	phosphatase activity
HBA75_28675	COG1475	DNA binding
HBA75_28695	COG1132	(ABC) transporter
HBA75_28700	COG1131	(ABC) transporter
HBA75_28735	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_28735	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_28770	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBA75_28790	COG1131	(ABC) transporter
HBA75_28800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBA75_28805	COG1132	(ABC) transporter
HBA75_28855	COG2801	Transposase and inactivated derivatives
HBA75_28870	COG0457	Tetratricopeptide repeat
HBA75_28880	COG3397	chitin binding
HBA75_28925	COG0697	spore germination
HBA75_28935	COG3397	chitin binding
HBA75_28940	COG0823	Involved in the tonB-independent uptake of proteins
HBA75_28950	COG1183	phosphatidylcholine synthase activity
HBA75_28975	COG5002	protein histidine kinase activity
HBA75_28975	COG3850	Histidine kinase
HBA75_28980	COG0745	RESPONSE REGULATOR receiver
HBA75_28990	COG1136	(ABC) transporter
HBA75_29015	COG2814	Major facilitator Superfamily
HBA75_29040	COG0318	PFAM AMP-dependent synthetase and ligase
HBA75_29045	COG2259	Doxx family
HBA75_29065	COG3104	oligopeptide transport
HBA75_29085	COG1073	alpha beta
HBA75_29095	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_29140	COG1131	(ABC) transporter
HBA75_29175	COG4974	Belongs to the 'phage' integrase family
HBA75_29230	COG1309	transcriptional regulator
HBA75_29240	COG1136	(ABC) transporter
HBA75_29275	COG0457	Tetratricopeptide repeat
HBA75_29330	COG1802	Transcriptional regulator
HBA75_29335	COG0697	spore germination
HBA75_29355	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HBA75_29370	COG0456	acetyltransferase
HBA75_29380	COG2184	nucleotidyltransferase activity
HBA75_29390	COG1522	sequence-specific DNA binding
HBA75_29395	COG0531	amino acid
HBA75_29415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBA75_29435	COG0824	Thioesterase
HBA75_29440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_29465	COG0546	phosphoglycolate phosphatase activity
HBA75_29470	COG1349	DNA-binding transcription factor activity
HBA75_29655	COG3344	reverse transcriptase
HBA75_29670	COG3344	reverse transcriptase
HBA75_29815	COG0457	Tetratricopeptide repeat
HBA75_29830	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HBA75_29835	COG0494	nUDIX hydrolase
HBA75_29840	COG0542	response to heat
HBA75_29875	COG1522	sequence-specific DNA binding
HBA75_29880	COG0288	reversible hydration of carbon dioxide
HBA75_29885	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HBA75_29890	COG2233	PERMEase
HBA75_29915	COG1687	branched-chain amino acid
HBA75_29920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBA75_29925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBA75_29930	COG1361	Conserved repeat domain
HBA75_29960	COG0741	lytic transglycosylase activity
HBA75_29965	COG0739	heme binding
HBA75_29970	COG1388	LysM domain
HBA75_29970	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_29970	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_29985	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_30060	COG3853	Toxic anion resistance protein (TelA)
HBA75_30070	COG0861	Integral membrane protein TerC family
HBA75_30075	COG2310	stress, protein
HBA75_30080	COG2310	stress, protein
HBA75_30085	COG2310	stress, protein
HBA75_30090	COG1940	carbohydrate kinase activity
HBA75_30115	COG2270	Major facilitator Superfamily
HBA75_30165	COG1116	anion transmembrane transporter activity
HBA75_30170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBA75_30175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBA75_30195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HBA75_30225	COG2190	(PTS) system
HBA75_30225	COG1263	PTS System
HBA75_30225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HBA75_30230	COG0366	Alpha amylase catalytic
HBA75_30235	COG0277	FAD linked oxidase domain protein
HBA75_30250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBA75_30255	COG0549	Belongs to the carbamate kinase family
HBA75_30285	COG0840	transmembrane signaling receptor activity
HBA75_30295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBA75_30300	COG0765	amino acid transport
HBA75_30325	COG2814	Major facilitator Superfamily
HBA75_30330	COG3541	Predicted nucleotidyltransferase
HBA75_30350	COG5002	protein histidine kinase activity
HBA75_30375	COG0166	Belongs to the GPI family
HBA75_30385	COG0492	ferredoxin-NADP+ reductase activity
HBA75_30390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HBA75_30395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_30400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBA75_30420	COG0450	alkyl hydroperoxide reductase
HBA75_30435	COG1473	amidohydrolase
HBA75_30465	COG4807	Protein conserved in bacteria
HBA75_30470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBA75_30475	COG3409	Peptidoglycan-binding domain 1 protein
HBA75_30475	COG1388	LysM domain
HBA75_30475	COG5632	N-Acetylmuramoyl-L-alanine amidase
HBA75_30485	COG3547	Transposase (IS116 IS110 IS902 family)
HBA75_30595	COG0582	viral genome integration into host DNA
HBA75_30645	COG3829	transcription factor binding
HBA75_30660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBA75_30665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HBA75_30685	COG0535	radical SAM domain protein
HBA75_30695	COG0387	Pfam Sodium calcium exchanger
HBA75_30700	COG3871	stress protein (general stress protein 26)
HBA75_30710	COG2801	Transposase and inactivated derivatives
HBA75_30730	COG0586	Pfam SNARE associated Golgi protein
HBA75_30740	COG0681	Belongs to the peptidase S26 family
HBA75_30750	COG0697	spore germination
HBA75_30755	COG2217	Heavy metal translocating P-type atpase
HBA75_30760	COG1295	ribonuclease BN
HBA75_30770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBA75_30785	COG2801	Transposase and inactivated derivatives
HBA75_31040	COG2801	Transposase and inactivated derivatives
HBA75_31055	COG3611	Membrane attachment protein