locus-tag	class	description
FHE73_00010	COG0592	DNA-directed DNA polymerase activity
FHE73_00015	COG2501	S4 domain
FHE73_00025	COG0187	DNA topoisomerase II activity
FHE73_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHE73_00065	COG0516	GMP reductase activity
FHE73_00065	COG0517	IMP dehydrogenase activity
FHE73_00070	COG1686	Belongs to the peptidase S11 family
FHE73_00100	COG1428	Deoxynucleoside kinase
FHE73_00105	COG1428	Deoxynucleoside kinase
FHE73_00110	COG1335	isochorismatase
FHE73_00120	COG0590	tRNA wobble adenosine to inosine editing
FHE73_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHE73_00185	COG1982	Orn Lys Arg decarboxylase major
FHE73_00195	COG0470	DNA polymerase III
FHE73_00200	COG1774	PSP1 C-terminal conserved region
FHE73_00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FHE73_00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FHE73_00225	COG2002	toxin-antitoxin pair type II binding
FHE73_00235	COG0084	hydrolase, TatD family'
FHE73_00255	COG4466	Protein conserved in bacteria
FHE73_00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FHE73_00275	COG0251	oxidation-reduction process
FHE73_00290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHE73_00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FHE73_00310	COG2002	toxin-antitoxin pair type II binding
FHE73_00315	COG2244	polysaccharide biosynthetic process
FHE73_00320	COG3956	TIGRFAM MazG family protein
FHE73_00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FHE73_00345	COG1098	S1 RNA binding domain
FHE73_00360	COG2208	phosphoserine phosphatase activity
FHE73_00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FHE73_00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHE73_00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHE73_00400	COG0512	Glutamine amidotransferase of anthranilate synthase
FHE73_00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHE73_00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FHE73_00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FHE73_00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FHE73_00425	COG1396	sequence-specific DNA binding
FHE73_00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHE73_00580	COG3880	PFAM UvrB UvrC protein
FHE73_00590	COG0542	response to heat
FHE73_00595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FHE73_00605	COG4956	integral membrane protein (PIN domain superfamily)
FHE73_00625	COG1045	serine acetyltransferase
FHE73_00640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHE73_00645	COG3688	RNA-binding protein containing a PIN domain
FHE73_00655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FHE73_00660	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FHE73_00665	COG0250	Participates in transcription elongation, termination and antitermination
FHE73_00690	COG2813	Specifically methylates the guanine in position
FHE73_00705	COG1358	cellular component organization or biogenesis
FHE73_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FHE73_00840	COG0201	protein transport
FHE73_00850	COG0024	Methionine aminopeptidase
FHE73_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FHE73_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHE73_00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHE73_00925	COG0489	protein tyrosine kinase activity
FHE73_00935	COG2194	sulfuric ester hydrolase activity
FHE73_00940	COG0726	polysaccharide deacetylase
FHE73_01020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FHE73_01025	COG4856	YbbR-like protein
FHE73_01065	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_01070	COG2011	ABC-type metal ion transport system permease component
FHE73_01075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHE73_01080	COG1464	Belongs to the NlpA lipoprotein family
FHE73_01085	COG0604	alcohol dehydrogenase
FHE73_01095	COG0277	FAD linked oxidase domain protein
FHE73_01100	COG2271	Major facilitator Superfamily
FHE73_01110	COG2814	Major facilitator Superfamily
FHE73_01125	COG2207	Transcriptional regulator
FHE73_01135	COG1309	transcriptional regulator
FHE73_01145	COG4166	transmembrane transport
FHE73_01150	COG4166	transmembrane transport
FHE73_01155	COG0656	L-ascorbic acid biosynthetic process
FHE73_01170	COG4149	molybdate abc transporter
FHE73_01175	COG0725	ABC transporter, periplasmic molybdate-binding protein
FHE73_01180	COG1910	domain protein
FHE73_01195	COG0697	spore germination
FHE73_01210	COG0204	Acyl-transferase
FHE73_01220	COG1609	Transcriptional regulator
FHE73_01230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_01250	COG5298	Protein conserved in bacteria
FHE73_01270	COG0488	(ABC) transporter
FHE73_01275	COG4585	Histidine kinase
FHE73_01280	COG2197	response regulator
FHE73_01285	COG1131	(ABC) transporter
FHE73_01290	COG0842	Transport permease protein
FHE73_01290	COG1511	domain protein
FHE73_01295	COG0842	Transport permease protein
FHE73_01305	COG0747	negative chemotaxis
FHE73_01310	COG0601	transmembrane transport
FHE73_01320	COG0444	Belongs to the ABC transporter superfamily
FHE73_01325	COG4608	Belongs to the ABC transporter superfamily
FHE73_01330	COG0561	phosphatase activity
FHE73_01360	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FHE73_01365	COG0179	Fumarylacetoacetate (FAA) hydrolase
FHE73_01380	COG0531	amino acid
FHE73_01385	COG2814	Major facilitator Superfamily
FHE73_01395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FHE73_01405	COG4294	response to UV
FHE73_01410	COG0705	Rhomboid family
FHE73_01420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FHE73_01425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHE73_01430	COG0864	Transcriptional regulator
FHE73_01435	COG2337	Toxic component of a toxin-antitoxin (TA) module
FHE73_01440	COG2183	response to ionizing radiation
FHE73_01540	COG0802	atpase or kinase
FHE73_01545	COG1214	PFAM Peptidase M22, glycoprotease
FHE73_01550	COG0456	acetyltransferase
FHE73_01560	COG0488	(ABC) transporter
FHE73_01575	COG1266	CAAX protease self-immunity
FHE73_01595	COG2252	PERMEase
FHE73_01605	COG5002	protein histidine kinase activity
FHE73_01630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FHE73_01660	COG2226	methyltransferase
FHE73_01680	COG1215	transferase activity, transferring glycosyl groups
FHE73_01720	COG2205	protein histidine kinase activity
FHE73_01725	COG0745	RESPONSE REGULATOR receiver
FHE73_01745	COG0697	spore germination
FHE73_01775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FHE73_01780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FHE73_01785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FHE73_01795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHE73_01810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FHE73_01820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FHE73_01830	COG0151	Belongs to the GarS family
FHE73_01860	COG0210	DNA helicase
FHE73_01870	COG4851	CamS sex pheromone cAM373 precursor
FHE73_01885	COG1335	isochorismatase
FHE73_01900	COG2011	ABC-type metal ion transport system permease component
FHE73_01905	COG1464	Belongs to the NlpA lipoprotein family
FHE73_01920	COG0003	Pfam Anion-transporting ATPase
FHE73_01925	COG1846	Transcriptional regulator
FHE73_01930	COG4682	membrane
FHE73_01950	COG1597	lipid kinase activity
FHE73_01960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FHE73_01970	COG1012	belongs to the aldehyde dehydrogenase family
FHE73_01975	COG2076	Multidrug Resistance protein
FHE73_01985	COG2309	aminopeptidase activity
FHE73_02000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_02010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHE73_02015	COG4807	Protein conserved in bacteria
FHE73_02050	COG1473	amidohydrolase
FHE73_02070	COG0450	alkyl hydroperoxide reductase
FHE73_02075	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FHE73_02085	COG0235	Class ii aldolase
FHE73_02090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_02095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_02100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_02125	COG0166	Belongs to the GPI family
FHE73_02150	COG5002	protein histidine kinase activity
FHE73_02170	COG3541	Predicted nucleotidyltransferase
FHE73_02175	COG2814	Major facilitator Superfamily
FHE73_02180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FHE73_02180	COG0723	plastoquinol--plastocyanin reductase activity
FHE73_02190	COG0765	amino acid transport
FHE73_02195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHE73_02205	COG0840	transmembrane signaling receptor activity
FHE73_02230	COG0549	Belongs to the carbamate kinase family
FHE73_02235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHE73_02245	COG0366	Alpha amylase catalytic
FHE73_02250	COG1263	PTS System
FHE73_02250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHE73_02250	COG2190	(PTS) system
FHE73_02280	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FHE73_02300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FHE73_02305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FHE73_02310	COG1116	anion transmembrane transporter activity
FHE73_02365	COG2270	Major facilitator Superfamily
FHE73_02395	COG2310	stress, protein
FHE73_02400	COG2310	stress, protein
FHE73_02405	COG2310	stress, protein
FHE73_02410	COG0861	Integral membrane protein TerC family
FHE73_02420	COG3853	Toxic anion resistance protein (TelA)
FHE73_02435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHE73_02445	COG1295	ribonuclease BN
FHE73_02450	COG2217	Heavy metal translocating P-type atpase
FHE73_02455	COG0697	spore germination
FHE73_02475	COG0586	Pfam SNARE associated Golgi protein
FHE73_02490	COG3871	stress protein (general stress protein 26)
FHE73_02495	COG0387	Pfam Sodium calcium exchanger
FHE73_02505	COG0535	radical SAM domain protein
FHE73_02525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FHE73_02545	COG3829	transcription factor binding
FHE73_02555	COG0833	amino acid
FHE73_02560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHE73_02590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHE73_02590	COG1263	PTS System
FHE73_02595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FHE73_02610	COG0463	Glycosyl transferase, family 2
FHE73_02620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FHE73_02620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FHE73_02635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FHE73_02665	COG1228	amidohydrolase
FHE73_02670	COG1090	epimerase
FHE73_02700	COG1988	membrane-bound metal-dependent
FHE73_02705	COG1194	a g-specific adenine glycosylase
FHE73_02730	COG1132	(ABC) transporter
FHE73_02735	COG4129	membrane
FHE73_02740	COG0067	glutamate synthase
FHE73_02740	COG0069	glutamate synthase activity
FHE73_02740	COG0070	glutamate synthase
FHE73_02750	COG4555	ABC transporter
FHE73_02770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FHE73_02775	COG0735	belongs to the Fur family
FHE73_02895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FHE73_02920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FHE73_02925	COG1716	ATPase activity
FHE73_02925	COG5001	Diguanylate cyclase
FHE73_02930	COG2766	serine protein kinase
FHE73_02950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FHE73_02960	COG1585	Membrane protein implicated in regulation of membrane protease activity
FHE73_02965	COG2268	Band 7 protein
FHE73_02975	COG3290	protein histidine kinase activity
FHE73_02980	COG4565	transcriptional regulatory protein
FHE73_02985	COG2851	Citrate transporter
FHE73_03010	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FHE73_03015	COG3842	ATPase activity
FHE73_03020	COG1175	transmembrane transport
FHE73_03025	COG0395	ABC-type sugar transport system, permease component
FHE73_03035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FHE73_03040	COG0745	RESPONSE REGULATOR receiver
FHE73_03045	COG5002	protein histidine kinase activity
FHE73_03055	COG4990	cell redox homeostasis
FHE73_03065	COG3290	protein histidine kinase activity
FHE73_03070	COG4565	transcriptional regulatory protein
FHE73_03075	COG3493	citrate carrier protein
FHE73_03080	COG0281	malic enzyme
FHE73_03090	COG0697	spore germination
FHE73_03095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_03105	COG5002	protein histidine kinase activity
FHE73_03120	COG0454	-acetyltransferase
FHE73_03120	COG0456	acetyltransferase
FHE73_03125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FHE73_03130	COG3383	formate dehydrogenase (NAD+) activity
FHE73_03135	COG2427	Protein of unknown function (DUF1641)
FHE73_03150	COG0531	amino acid
FHE73_03155	COG0640	Transcriptional regulator
FHE73_03160	COG2217	Heavy metal translocating P-type atpase
FHE73_03165	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FHE73_03180	COG3227	Zinc metalloprotease (Elastase)
FHE73_03200	COG2720	vancomycin resistance protein
FHE73_03205	COG1316	TRANSCRIPTIONal
FHE73_03210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_03215	COG0346	lactoylglutathione lyase activity
FHE73_03220	COG1253	flavin adenine dinucleotide binding
FHE73_03225	COG1027	Aspartate ammonia-lyase
FHE73_03230	COG1620	l-lactate permease
FHE73_03245	COG3104	oligopeptide transport
FHE73_03250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_03255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_03275	COG0156	8-amino-7-oxononanoate synthase activity
FHE73_03280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FHE73_03290	COG4548	von Willebrand factor, type A
FHE73_03295	COG0714	Associated with various cellular activities
FHE73_03315	COG0531	amino acid
FHE73_03320	COG2188	Transcriptional regulator
FHE73_03325	COG1263	PTS System
FHE73_03325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHE73_03330	COG0366	Alpha amylase catalytic
FHE73_03345	COG0697	spore germination
FHE73_03350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FHE73_03355	COG1115	amino acid carrier protein
FHE73_03365	COG1126	abc transporter atp-binding protein
FHE73_03370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHE73_03375	COG0765	amino acid transport
FHE73_03380	COG0765	amino acid transport
FHE73_03385	COG0833	amino acid
FHE73_03400	COG1595	DNA-templated transcription, initiation
FHE73_03410	COG2378	regulation of single-species biofilm formation
FHE73_03415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FHE73_03420	COG5002	protein histidine kinase activity
FHE73_03435	COG0659	secondary active sulfate transmembrane transporter activity
FHE73_03450	COG2271	Major facilitator Superfamily
FHE73_03455	COG1846	Transcriptional regulator
FHE73_03460	COG0477	Major facilitator Superfamily
FHE73_03465	COG1609	Transcriptional regulator
FHE73_03470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FHE73_03485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FHE73_03490	COG1879	ABC-type sugar transport system periplasmic component
FHE73_03495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FHE73_03510	COG1063	alcohol dehydrogenase
FHE73_03565	COG0840	transmembrane signaling receptor activity
FHE73_03570	COG3584	3D domain protein
FHE73_03570	COG3583	domain protein
FHE73_03575	COG1476	TRANSCRIPTIONal
FHE73_03595	COG3104	oligopeptide transport
FHE73_03600	COG1114	Component of the transport system for branched-chain amino acids
FHE73_03615	COG1113	amino acid transport
FHE73_03620	COG2252	PERMEase
FHE73_03635	COG2153	protein acetylation
FHE73_03645	COG0475	glutathione-regulated potassium exporter activity
FHE73_03645	COG0569	domain protein
FHE73_03660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FHE73_03665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FHE73_03670	COG0833	amino acid
FHE73_03675	COG4990	cell redox homeostasis
FHE73_03690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHE73_03695	COG0697	spore germination
FHE73_03700	COG0531	amino acid
FHE73_03710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FHE73_03715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FHE73_03720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FHE73_03720	COG1918	ferrous iron import across plasma membrane
FHE73_03725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FHE73_03730	COG0573	inorganic phosphate transmembrane transporter activity
FHE73_03735	COG0581	inorganic phosphate transmembrane transporter activity
FHE73_03745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FHE73_03865	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FHE73_03885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FHE73_03890	COG1116	anion transmembrane transporter activity
FHE73_03895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FHE73_03900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FHE73_03905	COG0352	thiamine-phosphate diphosphorylase activity
FHE73_03910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FHE73_03915	COG2104	thiamine diphosphate biosynthetic process
FHE73_03925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FHE73_03930	COG0351	phosphomethylpyrimidine kinase
FHE73_03970	COG2205	protein histidine kinase activity
FHE73_03975	COG2814	Major facilitator Superfamily
FHE73_03980	COG1846	Transcriptional regulator
FHE73_03995	COG2252	PERMEase
FHE73_04000	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_04015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FHE73_04020	COG1621	beta-fructofuranosidase activity
FHE73_04025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHE73_04025	COG1263	PTS System
FHE73_04030	COG1609	Transcriptional regulator
FHE73_04080	COG0778	Nitroreductase
FHE73_04085	COG2719	SpoVR family
FHE73_04095	COG3591	Belongs to the peptidase S1B family
FHE73_04105	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHE73_04110	COG1937	Protein conserved in bacteria
FHE73_04115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHE73_04115	COG0425	Belongs to the sulfur carrier protein TusA family
FHE73_04120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_04120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHE73_04125	COG0425	Belongs to the sulfur carrier protein TusA family
FHE73_04130	COG0425	Belongs to the sulfur carrier protein TusA family
FHE73_04130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHE73_04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHE73_04140	COG2210	Belongs to the sulfur carrier protein TusA family
FHE73_04145	COG0730	response to heat
FHE73_04155	COG1316	TRANSCRIPTIONal
FHE73_04160	COG0604	alcohol dehydrogenase
FHE73_04165	COG1283	sodium-dependent phosphate transmembrane transporter activity
FHE73_04185	COG3711	transcriptional antiterminator
FHE73_04185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHE73_04190	COG1447	Phosphotransferase system cellobiose-specific component IIA
FHE73_04195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHE73_04220	COG1388	LysM domain
FHE73_04220	COG3584	3D domain protein
FHE73_04225	COG0577	efflux transmembrane transporter activity
FHE73_04230	COG1136	(ABC) transporter
FHE73_04240	COG5522	Integral membrane protein (intg_mem_TP0381)
FHE73_04260	COG1114	Component of the transport system for branched-chain amino acids
FHE73_04265	COG3546	catalase activity
FHE73_04300	COG0586	Pfam SNARE associated Golgi protein
FHE73_04330	COG0531	amino acid
FHE73_04335	COG0475	glutathione-regulated potassium exporter activity
FHE73_04345	COG1737	Transcriptional regulator
FHE73_04355	COG1263	PTS System
FHE73_04355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHE73_04365	COG2259	Doxx family
FHE73_04385	COG1522	sequence-specific DNA binding
FHE73_04395	COG2076	Multidrug Resistance protein
FHE73_04405	COG1309	transcriptional regulator
FHE73_04410	COG2814	Major facilitator Superfamily
FHE73_04415	COG4533	DNA binding
FHE73_04420	COG2814	Major facilitator Superfamily
FHE73_04430	COG0693	protein deglycase activity
FHE73_04445	COG0531	amino acid
FHE73_04450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FHE73_04460	COG1012	belongs to the aldehyde dehydrogenase family
FHE73_04475	COG1132	(ABC) transporter
FHE73_04480	COG1132	(ABC) transporter
FHE73_04490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHE73_04495	COG0765	amino acid transport
FHE73_04500	COG1126	abc transporter atp-binding protein
FHE73_04515	COG0189	ligase activity
FHE73_04545	COG0028	Belongs to the TPP enzyme family
FHE73_04550	COG3527	Alpha-acetolactate decarboxylase
FHE73_04565	COG0561	phosphatase activity
FHE73_04575	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_04575	COG5632	N-Acetylmuramoyl-L-alanine amidase
FHE73_04580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHE73_04585	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_04600	COG0659	secondary active sulfate transmembrane transporter activity
FHE73_04605	COG2244	polysaccharide biosynthetic process
FHE73_04625	COG1024	Enoyl-CoA hydratase
FHE73_04645	COG1363	Peptidase, m42
FHE73_04685	COG0601	transmembrane transport
FHE73_04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHE73_04695	COG0444	Belongs to the ABC transporter superfamily
FHE73_04700	COG4608	Belongs to the ABC transporter superfamily
FHE73_04715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_04850	COG0477	Major facilitator Superfamily
FHE73_04855	COG3290	protein histidine kinase activity
FHE73_04860	COG4565	transcriptional regulatory protein
FHE73_04865	COG3181	Tripartite tricarboxylate transporter family receptor
FHE73_04895	COG0789	Transcriptional regulator
FHE73_04895	COG4978	Transcriptional regulator
FHE73_04910	COG0305	Participates in initiation and elongation during chromosome replication
FHE73_04930	COG0477	Major facilitator Superfamily
FHE73_05060	COG3320	Male sterility
FHE73_05060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHE73_05080	COG1183	phosphatidylcholine synthase activity
FHE73_05100	COG2376	Dihydroxyacetone kinase
FHE73_05115	COG2376	Dihydroxyacetone kinase
FHE73_05130	COG0457	Tetratricopeptide repeat
FHE73_05160	COG3584	3D domain protein
FHE73_05160	COG1388	LysM domain
FHE73_05165	COG1388	LysM domain
FHE73_05165	COG0791	NLP P60 protein
FHE73_05170	COG2373	Large extracellular alpha-helical protein
FHE73_05195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FHE73_05290	COG1191	sigma factor activity
FHE73_05300	COG2208	phosphoserine phosphatase activity
FHE73_05305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHE73_05310	COG0784	Response regulator, receiver
FHE73_05310	COG5002	protein histidine kinase activity
FHE73_05310	COG2205	protein histidine kinase activity
FHE73_05330	COG0393	Putative heavy-metal-binding
FHE73_05350	COG4585	Histidine kinase
FHE73_05355	COG2197	response regulator
FHE73_05380	COG0420	3'-5' exonuclease activity
FHE73_05385	COG4717	serine-type aminopeptidase activity
FHE73_05395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FHE73_05400	COG0346	lactoylglutathione lyase activity
FHE73_05405	COG0346	lactoylglutathione lyase activity
FHE73_05410	COG0457	Tetratricopeptide repeat
FHE73_05420	COG2267	carboxylic ester hydrolase activity
FHE73_05440	COG2140	Oxalate decarboxylase
FHE73_05445	COG3620	sequence-specific DNA binding
FHE73_05450	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FHE73_05455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FHE73_05465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FHE73_05475	COG1595	DNA-templated transcription, initiation
FHE73_05490	COG3973	AAA domain
FHE73_05525	COG4980	gas vesicle protein
FHE73_05530	COG0537	adenosine 5'-monophosphoramidase activity
FHE73_05535	COG1131	(ABC) transporter
FHE73_05540	COG4473	ABC transporter
FHE73_05555	COG1309	transcriptional regulator
FHE73_05560	COG3402	PFAM membrane-flanked domain
FHE73_05565	COG3428	Bacterial PH domain
FHE73_05600	COG0697	spore germination
FHE73_05605	COG3402	PFAM membrane-flanked domain
FHE73_05615	COG2329	Antibiotic biosynthesis monooxygenase
FHE73_05620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHE73_05675	COG1511	domain protein
FHE73_05695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_05700	COG1609	Transcriptional regulator
FHE73_05710	COG1234	tRNA 3'-trailer cleavage
FHE73_05715	COG0095	Lipoate-protein ligase
FHE73_05730	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_05760	COG1408	metallophosphoesterase
FHE73_05765	COG1078	dGTPase activity
FHE73_05775	COG1595	DNA-templated transcription, initiation
FHE73_05785	COG3708	Transcriptional regulator
FHE73_05785	COG2207	Transcriptional regulator
FHE73_05790	COG2205	protein histidine kinase activity
FHE73_05795	COG0745	RESPONSE REGULATOR receiver
FHE73_05815	COG0501	Belongs to the peptidase M48B family
FHE73_05820	COG0840	transmembrane signaling receptor activity
FHE73_05825	COG3693	PFAM glycoside hydrolase, family 10
FHE73_05835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FHE73_05840	COG2224	Isocitrate lyase
FHE73_05855	COG1278	Cold shock
FHE73_05880	COG0398	Pfam SNARE associated Golgi protein
FHE73_05900	COG0202	RNA polymerase activity
FHE73_05940	COG0179	Fumarylacetoacetate (FAA) hydrolase
FHE73_05965	COG0367	asparagine synthase
FHE73_05975	COG0753	catalase activity
FHE73_05980	COG0004	ammonium transporteR
FHE73_06005	COG2996	Protein conserved in bacteria
FHE73_06020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_06035	COG0561	phosphatase activity
FHE73_06055	COG2267	carboxylic ester hydrolase activity
FHE73_06075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FHE73_06080	COG5504	Zn-dependent protease
FHE73_06090	COG0180	Tryptophanyl-tRNA synthetase
FHE73_06105	COG4166	transmembrane transport
FHE73_06110	COG0601	transmembrane transport
FHE73_06115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHE73_06120	COG0444	Belongs to the ABC transporter superfamily
FHE73_06125	COG4608	Belongs to the ABC transporter superfamily
FHE73_06135	COG0534	Mate efflux family protein
FHE73_06140	COG4166	transmembrane transport
FHE73_06155	COG1393	Belongs to the ArsC family
FHE73_06160	COG0861	Integral membrane protein TerC family
FHE73_06170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHE73_06180	COG1164	Oligoendopeptidase f
FHE73_06190	COG2346	COG2346, Truncated hemoglobins
FHE73_06195	COG4116	CYTH
FHE73_06205	COG2357	RelA SpoT domain protein
FHE73_06215	COG0564	pseudouridine synthase activity
FHE73_06230	COG0772	Belongs to the SEDS family
FHE73_06235	COG1216	Glycosyl transferase, family 2
FHE73_06255	COG0463	Glycosyl transferase, family 2
FHE73_06255	COG0457	Tetratricopeptide repeat
FHE73_06275	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FHE73_06290	COG1091	dTDP-4-dehydrorhamnose reductase activity
FHE73_06340	COG2153	protein acetylation
FHE73_06350	COG2382	esterase
FHE73_06370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHE73_06385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FHE73_06385	COG0512	Glutamine amidotransferase of anthranilate synthase
FHE73_06420	COG1620	l-lactate permease
FHE73_06430	COG5634	Uncharacterized conserved protein (DUF2278)
FHE73_06480	COG0508	dehydrogenase complex catalyzes the overall conversion of
FHE73_06490	COG1476	TRANSCRIPTIONal
FHE73_06590	COG4974	Belongs to the 'phage' integrase family
FHE73_06620	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FHE73_06650	COG0582	viral genome integration into host DNA
FHE73_06675	COG1686	Belongs to the peptidase S11 family
FHE73_06680	COG0681	Belongs to the peptidase S26 family
FHE73_06715	COG1012	belongs to the aldehyde dehydrogenase family
FHE73_06725	COG1176	ABC-type spermidine putrescine transport system, permease component I
FHE73_06730	COG1177	transmembrane transport
FHE73_06735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FHE73_06745	COG2409	Drug exporters of the RND superfamily
FHE73_06755	COG0564	pseudouridine synthase activity
FHE73_06765	COG2340	Cysteine-rich secretory protein family
FHE73_06770	COG0247	lactate metabolic process
FHE73_06775	COG0277	FAD linked oxidase domain protein
FHE73_06780	COG3835	regulator
FHE73_06790	COG0745	RESPONSE REGULATOR receiver
FHE73_06795	COG5002	protein histidine kinase activity
FHE73_06800	COG2186	Transcriptional regulator
FHE73_06820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FHE73_06830	COG2116	formate transmembrane transporter activity
FHE73_06835	COG0861	Integral membrane protein TerC family
FHE73_06840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHE73_06850	COG2030	dehydratase
FHE73_06870	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_06875	COG3243	poly(R)-hydroxyalkanoic acid synthase
FHE73_06885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHE73_06900	COG1840	ABC-type Fe3 transport system, periplasmic component
FHE73_06905	COG3842	ATPase activity
FHE73_06930	COG1349	DNA-binding transcription factor activity
FHE73_06940	COG0235	Class ii aldolase
FHE73_06950	COG2861	carbohydrate metabolic process
FHE73_06960	COG3852	Histidine kinase
FHE73_06965	COG1846	Transcriptional regulator
FHE73_06975	COG2318	DinB family
FHE73_06980	COG5002	protein histidine kinase activity
FHE73_06990	COG0720	synthase
FHE73_07005	COG4873	Protein conserved in bacteria
FHE73_07035	COG1780	Probably involved in ribonucleotide reductase function
FHE73_07040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHE73_07045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHE73_07050	COG1725	Transcriptional regulator
FHE73_07055	COG1131	(ABC) transporter
FHE73_07065	COG1131	(ABC) transporter
FHE73_07070	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FHE73_07085	COG1522	sequence-specific DNA binding
FHE73_07095	COG1335	isochorismatase
FHE73_07105	COG1619	proteins homologs of microcin C7 resistance protein MccF
FHE73_07110	COG2070	2-Nitropropane dioxygenase
FHE73_07115	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FHE73_07125	COG1696	Membrane protein involved in D-alanine export
FHE73_07145	COG0716	FMN binding
FHE73_07195	COG1846	Transcriptional regulator
FHE73_07205	COG1301	dicarboxylic acid transport
FHE73_07210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHE73_07215	COG4709	membrane
FHE73_07220	COG3874	Sporulation protein YtfJ
FHE73_07240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHE73_07245	COG0028	Belongs to the TPP enzyme family
FHE73_07250	COG0440	acetolactate synthase activity
FHE73_07325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FHE73_07340	COG1183	phosphatidylcholine synthase activity
FHE73_07345	COG1368	sulfuric ester hydrolase activity
FHE73_07355	COG0019	diaminopimelate decarboxylase activity
FHE73_07375	COG0529	Catalyzes the synthesis of activated sulfate
FHE73_07380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FHE73_07400	COG1648	precorrin-2 dehydrogenase activity
FHE73_07405	COG0733	neurotransmitter:sodium symporter activity
FHE73_07425	COG1757	Na H antiporter
FHE73_07440	COG4758	membrane
FHE73_07445	COG4585	Histidine kinase
FHE73_07450	COG2197	response regulator
FHE73_07460	COG1114	Component of the transport system for branched-chain amino acids
FHE73_07470	COG2226	methyltransferase
FHE73_07510	COG0730	response to heat
FHE73_07515	COG0306	phosphate transporter
FHE73_07520	COG1392	Phosphate transport regulator
FHE73_07525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHE73_07540	COG3852	Histidine kinase
FHE73_07545	COG1801	Protein of unknown function DUF72
FHE73_07555	COG0582	viral genome integration into host DNA
FHE73_07560	COG5002	protein histidine kinase activity
FHE73_07575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FHE73_07575	COG0392	lysyltransferase activity
FHE73_07590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHE73_07595	COG1686	Belongs to the peptidase S11 family
FHE73_07600	COG2715	membrane protein required for spore maturation
FHE73_07605	COG0700	Nucleoside recognition
FHE73_07610	COG1187	pseudouridine synthase activity
FHE73_07620	COG1333	cytochrome c biogenesis protein
FHE73_07625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FHE73_07630	COG0745	RESPONSE REGULATOR receiver
FHE73_07635	COG5002	protein histidine kinase activity
FHE73_07640	COG2096	Adenosyltransferase
FHE73_07655	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FHE73_07660	COG1141	Ferredoxin
FHE73_07670	COG0514	ATP-dependent DNA helicase (RecQ)
FHE73_07675	COG1266	CAAX protease self-immunity
FHE73_07685	COG1408	metallophosphoesterase
FHE73_07690	COG0789	Transcriptional regulator
FHE73_07700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FHE73_07720	COG0492	ferredoxin-NADP+ reductase activity
FHE73_07725	COG0252	asparaginase activity
FHE73_07790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FHE73_07805	COG0142	geranyltranstransferase activity
FHE73_07815	COG0142	geranyltranstransferase activity
FHE73_07845	COG0457	Tetratricopeptide repeat
FHE73_07865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FHE73_07870	COG2010	Cytochrome c
FHE73_07870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FHE73_07875	COG4347	Protein of unknown function (DUF1405)
FHE73_07890	COG2738	Putative neutral zinc metallopeptidase
FHE73_07900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_07910	COG1694	Mazg nucleotide pyrophosphohydrolase
FHE73_07930	COG0438	transferase activity, transferring glycosyl groups
FHE73_07960	COG1199	ATP-dependent helicase activity
FHE73_07960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FHE73_07980	COG3935	DnaD domain protein
FHE73_07985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FHE73_07995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHE73_07995	COG4499	WXG100 protein secretion system (Wss), protein YukC
FHE73_08050	COG0116	Belongs to the methyltransferase superfamily
FHE73_08060	COG1199	ATP-dependent helicase activity
FHE73_08065	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FHE73_08075	COG0024	Methionine aminopeptidase
FHE73_08085	COG2233	PERMEase
FHE73_08090	COG2311	Membrane
FHE73_08095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FHE73_08105	COG0456	acetyltransferase
FHE73_08115	COG2897	thiosulfate sulfurtransferase activity
FHE73_08140	COG0754	glutathionylspermidine amidase activity
FHE73_08160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHE73_08185	COG3944	biosynthesis protein
FHE73_08195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHE73_08210	COG1215	transferase activity, transferring glycosyl groups
FHE73_08215	COG0438	transferase activity, transferring glycosyl groups
FHE73_08250	COG0328	RNA-DNA hybrid ribonuclease activity
FHE73_08290	COG1280	lysine exporter protein (LysE YggA)
FHE73_08305	COG3162	membrane
FHE73_08310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHE73_08315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FHE73_08325	COG0475	glutathione-regulated potassium exporter activity
FHE73_08330	COG0789	Transcriptional regulator
FHE73_08330	COG4978	Transcriptional regulator
FHE73_08340	COG2323	membrane
FHE73_08345	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FHE73_08385	COG1923	regulation of RNA biosynthetic process
FHE73_08395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FHE73_08400	COG1360	Flagellar Motor Protein
FHE73_08405	COG2201	protein-glutamate methylesterase activity
FHE73_08410	COG0643	Histidine kinase
FHE73_08410	COG2198	Histidine kinase
FHE73_08415	COG1776	CheC inhibitor of MCP methylation
FHE73_08415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FHE73_08430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHE73_08450	COG1256	bacterial-type flagellum assembly
FHE73_08455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FHE73_08460	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FHE73_08475	COG1815	bacterial-type flagellum-dependent cell motility
FHE73_08480	COG1558	bacterial-type flagellum-dependent cell motility
FHE73_08485	COG1677	Flagellar hook-basal body complex protein FliE
FHE73_08490	COG1766	The M ring may be actively involved in energy transduction
FHE73_08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FHE73_08505	COG1157	protein secretion by the type III secretion system
FHE73_08540	COG0835	chemotaxis
FHE73_08540	COG0784	Response regulator, receiver
FHE73_08550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FHE73_08555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FHE73_08560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FHE73_08565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FHE73_08570	COG0741	lytic transglycosylase activity
FHE73_08580	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FHE73_08585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FHE73_08585	COG1776	CheC inhibitor of MCP methylation
FHE73_08595	COG1338	Plays a role in the flagellum-specific transport system
FHE73_08600	COG1987	bacterial-type flagellum assembly
FHE73_08610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FHE73_08615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FHE73_08620	COG1419	protein localization to endoplasmic reticulum
FHE73_08625	COG4786	Flagellar basal body rod
FHE73_08630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHE73_08665	COG2329	Antibiotic biosynthesis monooxygenase
FHE73_08705	COG1177	transmembrane transport
FHE73_08740	COG0406	alpha-ribazole phosphatase activity
FHE73_08770	COG0367	asparagine synthase
FHE73_08800	COG1802	Transcriptional regulator
FHE73_08805	COG0697	spore germination
FHE73_08810	COG0523	cobalamin synthesis protein
FHE73_08820	COG0701	Predicted permease
FHE73_08835	COG1757	Na H antiporter
FHE73_08840	COG0789	Transcriptional regulator
FHE73_08865	COG0534	Mate efflux family protein
FHE73_08870	COG3340	Belongs to the peptidase S51 family
FHE73_08890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHE73_08920	COG2733	membrane
FHE73_08960	COG1131	(ABC) transporter
FHE73_08975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHE73_08980	COG0528	UMP kinase activity
FHE73_08990	COG1027	Aspartate ammonia-lyase
FHE73_08995	COG0281	malic enzyme
FHE73_09000	COG4191	Histidine kinase
FHE73_09005	COG0784	Response regulator, receiver
FHE73_09010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FHE73_09065	COG2814	Major facilitator Superfamily
FHE73_09085	COG1695	Transcriptional regulator
FHE73_09095	COG0477	Major facilitator Superfamily
FHE73_09105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHE73_09110	COG2223	nitrite transmembrane transporter activity
FHE73_09115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHE73_09135	COG0733	neurotransmitter:sodium symporter activity
FHE73_09145	COG5566	PFAM Mor transcription activator
FHE73_09150	COG2323	membrane
FHE73_09165	COG2084	Dehydrogenase
FHE73_09180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHE73_09190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHE73_09195	COG0028	Belongs to the TPP enzyme family
FHE73_09215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FHE73_09240	COG2814	Major facilitator Superfamily
FHE73_09245	COG3384	dioxygenase
FHE73_09255	COG3279	Response regulator of the LytR AlgR family
FHE73_09260	COG0427	acetyl-CoA hydrolase
FHE73_09280	COG4166	transmembrane transport
FHE73_09285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_09305	COG1914	H( )-stimulated, divalent metal cation uptake system
FHE73_09320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FHE73_09325	COG0531	amino acid
FHE73_09355	COG1266	CAAX protease self-immunity
FHE73_09360	COG1309	transcriptional regulator
FHE73_09370	COG2390	Transcriptional regulator
FHE73_09380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_09385	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FHE73_09425	COG4846	Membrane protein involved in cytochrome C biogenesis
FHE73_09435	COG0006	proline dipeptidase activity
FHE73_09445	COG2132	Multicopper oxidase
FHE73_09480	COG1114	Component of the transport system for branched-chain amino acids
FHE73_09495	COG2372	response to copper ion
FHE73_09495	COG1276	copper resistance
FHE73_09505	COG0697	spore germination
FHE73_09510	COG0583	DNA-binding transcription factor activity
FHE73_09515	COG1959	2 iron, 2 sulfur cluster binding
FHE73_09520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FHE73_09525	COG0778	Nitroreductase
FHE73_09535	COG0628	permease
FHE73_09540	COG0039	L-malate dehydrogenase activity
FHE73_09545	COG1231	oxidoreductase activity
FHE73_09555	COG0523	cobalamin synthesis protein
FHE73_09565	COG0411	ABC transporter
FHE73_09585	COG0583	DNA-binding transcription factor activity
FHE73_09595	COG1942	4-Oxalocrotonate Tautomerase
FHE73_09615	COG1271	oxidase subunit
FHE73_09620	COG1294	oxidase, subunit
FHE73_09625	COG4988	ABC transporter
FHE73_09630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FHE73_09640	COG1216	Glycosyl transferase, family 2
FHE73_09680	COG1686	Belongs to the peptidase S11 family
FHE73_09695	COG1388	LysM domain
FHE73_09695	COG0791	NLP P60 protein
FHE73_09705	COG1132	(ABC) transporter
FHE73_09710	COG0745	RESPONSE REGULATOR receiver
FHE73_09715	COG5002	protein histidine kinase activity
FHE73_09720	COG0300	oxidoreductase activity
FHE73_09730	COG0726	polysaccharide deacetylase
FHE73_09740	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FHE73_09750	COG0460	homoserine dehydrogenase
FHE73_09775	COG1316	TRANSCRIPTIONal
FHE73_09785	COG0745	RESPONSE REGULATOR receiver
FHE73_09790	COG5002	protein histidine kinase activity
FHE73_09795	COG0726	polysaccharide deacetylase
FHE73_09805	COG1285	pathogenesis
FHE73_09810	COG1247	-acetyltransferase
FHE73_09820	COG4264	IucA IucC family
FHE73_09825	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_09840	COG1082	Xylose isomerase domain protein TIM barrel
FHE73_09850	COG2814	Major facilitator Superfamily
FHE73_09855	COG1279	arginine transmembrane transporter activity
FHE73_09860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_09870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FHE73_09905	COG0577	efflux transmembrane transporter activity
FHE73_09910	COG2002	toxin-antitoxin pair type II binding
FHE73_09915	COG1404	Belongs to the peptidase S8 family
FHE73_09920	COG0640	Transcriptional regulator
FHE73_09925	COG0667	Aldo Keto reductase
FHE73_09930	COG2814	Major facilitator Superfamily
FHE73_09940	COG3152	Membrane
FHE73_09965	COG0840	transmembrane signaling receptor activity
FHE73_09980	COG3949	Membrane
FHE73_09985	COG0783	Belongs to the Dps family
FHE73_10000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHE73_10010	COG1231	oxidoreductase activity
FHE73_10015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_10020	COG4989	oxidoreductase activity
FHE73_10025	COG0523	cobalamin synthesis protein
FHE73_10030	COG0456	acetyltransferase
FHE73_10035	COG0803	Belongs to the bacterial solute-binding protein 9 family
FHE73_10040	COG0702	epimerase
FHE73_10050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHE73_10060	COG4166	transmembrane transport
FHE73_10085	COG5337	Spore coat protein CotH
FHE73_10090	COG1051	belongs to the nudix hydrolase family
FHE73_10095	COG0586	Pfam SNARE associated Golgi protein
FHE73_10100	COG2244	polysaccharide biosynthetic process
FHE73_10110	COG0701	Predicted permease
FHE73_10115	COG3689	TIGRFAM TIGR03943 family protein
FHE73_10120	COG1607	acyl-coa hydrolase
FHE73_10130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHE73_10145	COG0702	epimerase
FHE73_10150	COG2839	Protein conserved in bacteria
FHE73_10155	COG1253	flavin adenine dinucleotide binding
FHE73_10175	COG1114	Component of the transport system for branched-chain amino acids
FHE73_10180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHE73_10200	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHE73_10210	COG1876	peptidase activity
FHE73_10225	COG2211	Major facilitator Superfamily
FHE73_10240	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHE73_10250	COG0561	phosphatase activity
FHE73_10265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHE73_10280	COG1819	glycosyl
FHE73_10285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_10320	COG0456	acetyltransferase
FHE73_10360	COG4499	WXG100 protein secretion system (Wss), protein YukC
FHE73_10420	COG3874	Sporulation protein YtfJ
FHE73_10445	COG2226	methyltransferase
FHE73_10465	COG1082	Xylose isomerase domain protein TIM barrel
FHE73_10470	COG0346	lactoylglutathione lyase activity
FHE73_10480	COG0604	alcohol dehydrogenase
FHE73_10485	COG1595	DNA-templated transcription, initiation
FHE73_10500	COG0426	domain, Protein
FHE73_10500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FHE73_10510	COG0386	Belongs to the glutathione peroxidase family
FHE73_10515	COG1305	Transglutaminase-like
FHE73_10520	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FHE73_10525	COG0714	Associated with various cellular activities
FHE73_10530	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FHE73_10535	COG1140	nitrate reductase beta subunit
FHE73_10540	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FHE73_10545	COG2181	nitrate reductase activity
FHE73_10550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHE73_10555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FHE73_10560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FHE73_10565	COG0303	'Molybdopterin
FHE73_10570	COG0314	molybdopterin synthase activity
FHE73_10580	COG2223	nitrite transmembrane transporter activity
FHE73_10595	COG1648	precorrin-2 dehydrogenase activity
FHE73_10595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FHE73_10605	COG1587	Uroporphyrinogen-III synthase
FHE73_10605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FHE73_10610	COG2146	nitrite reductase [NAD(P)H] activity
FHE73_10615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FHE73_10620	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FHE73_10640	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FHE73_10655	COG2359	stage V sporulation protein S
FHE73_10700	COG0457	Tetratricopeptide repeat
FHE73_10715	COG1418	mRNA catabolic process
FHE73_10720	COG0488	(ABC) transporter
FHE73_10735	COG0629	single-stranded DNA binding
FHE73_10745	COG1413	lyase activity
FHE73_10760	COG2521	methyltransferase
FHE73_10760	COG2136	Putative SAM-dependent methyltransferase
FHE73_10765	COG0018	arginyl-trna synthetase
FHE73_10810	COG0017	Asparaginyl-tRNA synthetase
FHE73_10815	COG0733	neurotransmitter:sodium symporter activity
FHE73_10840	COG2610	gluconate transmembrane transporter activity
FHE73_10850	COG1794	racemase activity, acting on amino acids and derivatives
FHE73_10860	COG0456	acetyltransferase
FHE73_10865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FHE73_10885	COG0546	phosphoglycolate phosphatase activity
FHE73_10900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FHE73_10915	COG0768	penicillin binding
FHE73_10925	COG0204	Acyl-transferase
FHE73_10930	COG1272	protein, Hemolysin III
FHE73_10940	COG0805	protein transport
FHE73_10950	COG1307	EDD domain protein, DegV family
FHE73_10960	COG1999	signal sequence binding
FHE73_10965	COG0071	Belongs to the small heat shock protein (HSP20) family
FHE73_10970	COG0367	asparagine synthase
FHE73_10985	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHE73_10990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_10995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHE73_11015	COG1335	isochorismatase
FHE73_11025	COG0668	transmembrane transport
FHE73_11030	COG2203	Gaf domain
FHE73_11030	COG4585	Histidine kinase
FHE73_11035	COG2197	response regulator
FHE73_11040	COG1737	Transcriptional regulator
FHE73_11045	COG0384	phenazine biosynthesis protein PhzF
FHE73_11050	COG1064	alcohol dehydrogenase
FHE73_11075	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FHE73_11110	COG0517	IMP dehydrogenase activity
FHE73_11110	COG1125	glycine betaine transport
FHE73_11115	COG1174	glycine betaine transport
FHE73_11150	COG1253	flavin adenine dinucleotide binding
FHE73_11155	COG1012	belongs to the aldehyde dehydrogenase family
FHE73_11160	COG5506	Protein of unknown function (DUF1694)
FHE73_11175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FHE73_11180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FHE73_11185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FHE73_11190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHE73_11195	COG0456	acetyltransferase
FHE73_11200	COG3829	transcription factor binding
FHE73_11205	COG1509	lysine 2,3-aminomutase activity
FHE73_11240	COG0515	serine threonine protein kinase
FHE73_11240	COG3064	Membrane
FHE73_11240	COG4991	sh3 domain protein
FHE73_11250	COG0671	phosphoesterase, PA-phosphatase related
FHE73_11255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FHE73_11260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHE73_11360	COG0300	oxidoreductase activity
FHE73_11380	COG4499	WXG100 protein secretion system (Wss), protein YukC
FHE73_11380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHE73_11390	COG2814	Major facilitator Superfamily
FHE73_11395	COG4841	protein insertion into membrane
FHE73_11400	COG0372	Belongs to the citrate synthase family
FHE73_11405	COG2079	MmgE PrpD family protein
FHE73_11410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FHE73_11415	COG1960	acyl-CoA dehydrogenase activity
FHE73_11420	COG2084	Dehydrogenase
FHE73_11430	COG1280	lysine exporter protein (LysE YggA)
FHE73_11435	COG1024	Enoyl-CoA hydratase
FHE73_11450	COG0420	3'-5' exonuclease activity
FHE73_11455	COG0419	ATPase involved in DNA repair
FHE73_11460	COG0582	viral genome integration into host DNA
FHE73_11530	COG0582	viral genome integration into host DNA
FHE73_11540	COG3611	Membrane attachment protein
FHE73_11545	COG0582	viral genome integration into host DNA
FHE73_11655	COG2223	nitrite transmembrane transporter activity
FHE73_11660	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_11665	COG1169	isochorismate synthase
FHE73_11670	COG1021	2,3-dihydroxybenzoate-AMP ligase
FHE73_11675	COG3433	isochorismatase activity
FHE73_11675	COG1535	isochorismatase
FHE73_11680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FHE73_11685	COG3251	PFAM MbtH domain protein
FHE73_11690	COG2814	Major facilitator Superfamily
FHE73_11705	COG0776	regulation of translation
FHE73_11715	COG2318	DinB family
FHE73_11725	COG1115	amino acid carrier protein
FHE73_11740	COG2329	Antibiotic biosynthesis monooxygenase
FHE73_11745	COG1187	pseudouridine synthase activity
FHE73_11750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHE73_11755	COG1136	(ABC) transporter
FHE73_11795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHE73_11825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_11900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_11930	COG0583	DNA-binding transcription factor activity
FHE73_11935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHE73_11960	COG2258	MOSC domain
FHE73_11975	COG1132	(ABC) transporter
FHE73_11980	COG1132	(ABC) transporter
FHE73_12000	COG0582	viral genome integration into host DNA
FHE73_12015	COG1396	sequence-specific DNA binding
FHE73_12040	COG1484	DNA-dependent DNA replication
FHE73_12050	COG2002	toxin-antitoxin pair type II binding
FHE73_12115	COG0582	viral genome integration into host DNA
FHE73_12165	COG0740	serine-type endopeptidase activity
FHE73_12245	COG5632	N-Acetylmuramoyl-L-alanine amidase
FHE73_12245	COG1388	LysM domain
FHE73_12245	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_12265	COG0730	response to heat
FHE73_12295	COG1396	sequence-specific DNA binding
FHE73_12330	COG1595	DNA-templated transcription, initiation
FHE73_12355	COG1649	PFAM Uncharacterised BCR, COG1649
FHE73_12380	COG2971	BadF BadG BcrA BcrD
FHE73_12390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FHE73_12400	COG1846	Transcriptional regulator
FHE73_12415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_12430	COG1309	transcriptional regulator
FHE73_12450	COG3615	Tellurite resistance protein tehB
FHE73_12450	COG0500	methyltransferase
FHE73_12460	COG2226	methyltransferase
FHE73_12465	COG3961	Belongs to the TPP enzyme family
FHE73_12475	COG1846	Transcriptional regulator
FHE73_12505	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHE73_12530	COG2002	toxin-antitoxin pair type II binding
FHE73_12540	COG0730	response to heat
FHE73_12545	COG0110	maltose O-acetyltransferase activity
FHE73_12550	COG1686	Belongs to the peptidase S11 family
FHE73_12565	COG2814	Major facilitator Superfamily
FHE73_12605	COG1115	amino acid carrier protein
FHE73_12610	COG2066	Belongs to the glutaminase family
FHE73_12615	COG4191	Histidine kinase
FHE73_12620	COG0784	Response regulator, receiver
FHE73_12625	COG0697	spore germination
FHE73_12630	COG0531	amino acid
FHE73_12645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHE73_12655	COG0531	amino acid
FHE73_12660	COG0322	excinuclease ABC activity
FHE73_12680	COG2207	Transcriptional regulator
FHE73_12705	COG5002	protein histidine kinase activity
FHE73_12745	COG0741	lytic transglycosylase activity
FHE73_12750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_12775	COG1396	sequence-specific DNA binding
FHE73_12790	COG0726	polysaccharide deacetylase
FHE73_12805	COG0768	penicillin binding
FHE73_12810	COG1595	DNA-templated transcription, initiation
FHE73_12820	COG0768	penicillin binding
FHE73_12835	COG1408	metallophosphoesterase
FHE73_12845	COG1131	(ABC) transporter
FHE73_12855	COG1309	transcriptional regulator
FHE73_12870	COG1960	acyl-CoA dehydrogenase activity
FHE73_12875	COG0439	Biotin carboxylase
FHE73_12880	COG0511	ligase activity, forming carbon-carbon bonds
FHE73_12885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FHE73_12890	COG1024	Enoyl-CoA hydratase
FHE73_12895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FHE73_12900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FHE73_12920	COG0572	uridine kinase
FHE73_12940	COG1686	Belongs to the peptidase S11 family
FHE73_12965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FHE73_12980	COG3227	Zinc metalloprotease (Elastase)
FHE73_12985	COG2207	Transcriptional regulator
FHE73_13015	COG0789	Transcriptional regulator
FHE73_13020	COG2814	Major facilitator Superfamily
FHE73_13030	COG1733	regulation of RNA biosynthetic process
FHE73_13035	COG2226	methyltransferase
FHE73_13050	COG1942	4-Oxalocrotonate Tautomerase
FHE73_13055	COG0583	DNA-binding transcription factor activity
FHE73_13080	COG0697	spore germination
FHE73_13085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_13105	COG0693	protein deglycase activity
FHE73_13120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FHE73_13130	COG3386	PFAM SMP-30 Gluconolaconase
FHE73_13145	COG3773	Cell wall hydrolase
FHE73_13155	COG0745	RESPONSE REGULATOR receiver
FHE73_13160	COG2205	protein histidine kinase activity
FHE73_13175	COG1136	(ABC) transporter
FHE73_13180	COG0577	efflux transmembrane transporter activity
FHE73_13200	COG0460	homoserine dehydrogenase
FHE73_13205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_13215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FHE73_13245	COG0582	viral genome integration into host DNA
FHE73_13275	COG2002	toxin-antitoxin pair type II binding
FHE73_13345	COG0582	viral genome integration into host DNA
FHE73_13390	COG0740	serine-type endopeptidase activity
FHE73_13460	COG4824	toxin secretion phage lysis holin
FHE73_13510	COG2124	cytochrome p450
FHE73_13545	COG0561	phosphatase activity
FHE73_13550	COG5002	protein histidine kinase activity
FHE73_13560	COG1819	glycosyl
FHE73_13565	COG1794	racemase activity, acting on amino acids and derivatives
FHE73_13620	COG1476	TRANSCRIPTIONal
FHE73_13640	COG0500	methyltransferase
FHE73_13645	COG0747	negative chemotaxis
FHE73_13650	COG0601	transmembrane transport
FHE73_13660	COG0444	Belongs to the ABC transporter superfamily
FHE73_13665	COG4608	Belongs to the ABC transporter superfamily
FHE73_13750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FHE73_13765	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FHE73_13770	COG2068	MobA-Related Protein
FHE73_13795	COG3647	Membrane
FHE73_13805	COG2046	Belongs to the sulfate adenylyltransferase family
FHE73_13810	COG2046	Belongs to the sulfate adenylyltransferase family
FHE73_13815	COG3443	Belongs to the bacterial solute-binding protein 9 family
FHE73_13855	COG2205	protein histidine kinase activity
FHE73_13905	COG0604	alcohol dehydrogenase
FHE73_13910	COG0671	phosphoesterase, PA-phosphatase related
FHE73_13925	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_13965	COG2814	Major facilitator Superfamily
FHE73_13980	COG0584	glycerophosphoryl diester phosphodiesterase
FHE73_14000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_14005	COG0697	spore germination
FHE73_14045	COG2223	nitrite transmembrane transporter activity
FHE73_14065	COG0592	DNA-directed DNA polymerase activity
FHE73_14085	COG3878	Protein conserved in bacteria
FHE73_14110	COG4667	esterase of the alpha-beta hydrolase superfamily
FHE73_14150	COG0322	excinuclease ABC activity
FHE73_14190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FHE73_14220	COG0745	RESPONSE REGULATOR receiver
FHE73_14225	COG5002	protein histidine kinase activity
FHE73_14240	COG1136	(ABC) transporter
FHE73_14245	COG0577	efflux transmembrane transporter activity
FHE73_14250	COG1073	alpha beta
FHE73_14260	COG0076	glutamate decarboxylase activity
FHE73_14275	COG1523	belongs to the glycosyl hydrolase 13 family
FHE73_14280	COG3227	Zinc metalloprotease (Elastase)
FHE73_14285	COG0737	Belongs to the 5'-nucleotidase family
FHE73_14300	COG0201	protein transport
FHE73_14305	COG0697	spore germination
FHE73_14310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_14345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_14360	COG2959	enzyme of heme biosynthesis
FHE73_14365	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_14365	COG3773	Cell wall hydrolase
FHE73_14405	COG1309	transcriptional regulator
FHE73_14440	COG3284	Transcriptional regulator
FHE73_14455	COG1349	DNA-binding transcription factor activity
FHE73_14470	COG1959	2 iron, 2 sulfur cluster binding
FHE73_14495	COG0508	dehydrogenase complex catalyzes the overall conversion of
FHE73_14500	COG0022	dehydrogenase e1 component
FHE73_14505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FHE73_14515	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_14545	COG4176	ABC-type proline glycine betaine transport system permease component
FHE73_14550	COG0517	IMP dehydrogenase activity
FHE73_14550	COG4175	Glycine betaine
FHE73_14560	COG0740	serine-type endopeptidase activity
FHE73_14580	COG2153	protein acetylation
FHE73_14585	COG3397	chitin binding
FHE73_14605	COG2205	protein histidine kinase activity
FHE73_14610	COG2226	methyltransferase
FHE73_14615	COG2315	Protein conserved in bacteria
FHE73_14665	COG0456	acetyltransferase
FHE73_14670	COG3973	AAA domain
FHE73_14685	COG0514	ATP-dependent DNA helicase (RecQ)
FHE73_14715	COG4637	Psort location Cytoplasmic, score
FHE73_14730	COG3397	chitin binding
FHE73_14745	COG1162	GTPase activity
FHE73_14750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FHE73_14755	COG1115	amino acid carrier protein
FHE73_14760	COG1012	belongs to the aldehyde dehydrogenase family
FHE73_14765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FHE73_14775	COG3938	Belongs to the proline racemase family
FHE73_14780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FHE73_14825	COG1078	dGTPase activity
FHE73_14830	COG0586	Pfam SNARE associated Golgi protein
FHE73_14840	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FHE73_14845	COG4166	transmembrane transport
FHE73_14855	COG4948	Mandelate Racemase Muconate Lactonizing
FHE73_14870	COG0667	Aldo Keto reductase
FHE73_14915	COG3850	Histidine kinase
FHE73_14915	COG5002	protein histidine kinase activity
FHE73_14920	COG0745	RESPONSE REGULATOR receiver
FHE73_14955	COG1307	EDD domain protein, DegV family
FHE73_14995	COG2814	Major facilitator Superfamily
FHE73_15005	COG1664	Polymer-forming cytoskeletal
FHE73_15010	COG0789	Transcriptional regulator
FHE73_15015	COG4533	DNA binding
FHE73_15020	COG0477	Major facilitator Superfamily
FHE73_15020	COG2814	Major facilitator Superfamily
FHE73_15040	COG2261	transglycosylase associated protein
FHE73_15055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FHE73_15090	COG0436	Aminotransferase
FHE73_15095	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FHE73_15145	COG0628	permease
FHE73_15160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FHE73_15165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FHE73_15195	COG2746	aminoglycoside 3-N-acetyltransferase activity
FHE73_15215	COG0697	spore germination
FHE73_15240	COG4912	Dna alkylation repair
FHE73_15245	COG0346	lactoylglutathione lyase activity
FHE73_15255	COG0726	polysaccharide deacetylase
FHE73_15260	COG0861	Integral membrane protein TerC family
FHE73_15265	COG1368	sulfuric ester hydrolase activity
FHE73_15270	COG0488	(ABC) transporter
FHE73_15275	COG1033	growth of symbiont in host cell
FHE73_15275	COG2409	Drug exporters of the RND superfamily
FHE73_15280	COG1309	transcriptional regulator
FHE73_15295	COG0287	Prephenate dehydrogenase
FHE73_15310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FHE73_15310	COG1605	Chorismate mutase
FHE73_15360	COG3584	3D domain protein
FHE73_15360	COG1388	LysM domain
FHE73_15370	COG0346	lactoylglutathione lyase activity
FHE73_15385	COG1595	DNA-templated transcription, initiation
FHE73_15420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FHE73_15430	COG2390	Transcriptional regulator
FHE73_15435	COG1070	Carbohydrate kinase
FHE73_15465	COG2329	Antibiotic biosynthesis monooxygenase
FHE73_15485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_15500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHE73_15505	COG4187	Peptidase family M20/M25/M40
FHE73_15510	COG1414	Transcriptional regulator
FHE73_15520	COG0833	amino acid
FHE73_15530	COG3239	Fatty acid desaturase
FHE73_15540	COG2720	vancomycin resistance protein
FHE73_15545	COG1785	Belongs to the alkaline phosphatase family
FHE73_15555	COG3655	Transcriptional regulator
FHE73_15575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_15580	COG0346	lactoylglutathione lyase activity
FHE73_15605	COG0714	Associated with various cellular activities
FHE73_15630	COG0463	Glycosyl transferase, family 2
FHE73_15650	COG0463	Glycosyl transferase, family 2
FHE73_15660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FHE73_15665	COG0753	catalase activity
FHE73_15700	COG0714	Associated with various cellular activities
FHE73_15745	COG0778	Nitroreductase
FHE73_15750	COG1846	Transcriptional regulator
FHE73_15775	COG3831	ATPase activity
FHE73_15775	COG4884	unkown
FHE73_15795	COG2207	Transcriptional regulator
FHE73_15800	COG0456	acetyltransferase
FHE73_15815	COG0697	spore germination
FHE73_15820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_15865	COG0730	response to heat
FHE73_15875	COG0833	amino acid
FHE73_15890	COG4335	DNA alkylation repair
FHE73_15900	COG5002	protein histidine kinase activity
FHE73_15905	COG0745	RESPONSE REGULATOR receiver
FHE73_15915	COG0577	efflux transmembrane transporter activity
FHE73_15915	COG1136	(ABC) transporter
FHE73_15980	COG1984	allophanate hydrolase subunit 2
FHE73_15985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FHE73_15990	COG1414	Transcriptional regulator
FHE73_16005	COG0640	Transcriptional regulator
FHE73_16015	COG1960	acyl-CoA dehydrogenase activity
FHE73_16065	COG3848	Pyruvate phosphate dikinase
FHE73_16065	COG0574	Belongs to the PEP-utilizing enzyme family
FHE73_16075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_16090	COG5577	PFAM Coat F domain
FHE73_16095	COG3403	YqcI/YcgG family
FHE73_16100	COG1280	lysine exporter protein (LysE YggA)
FHE73_16105	COG1113	amino acid transport
FHE73_16130	COG1063	alcohol dehydrogenase
FHE73_16140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FHE73_16165	COG0737	Belongs to the 5'-nucleotidase family
FHE73_16170	COG2267	carboxylic ester hydrolase activity
FHE73_16175	COG1335	isochorismatase
FHE73_16185	COG0583	DNA-binding transcription factor activity
FHE73_16215	COG0583	DNA-binding transcription factor activity
FHE73_16255	COG0598	Magnesium transport protein CorA
FHE73_16280	COG1073	alpha beta
FHE73_16300	COG0415	Belongs to the DNA photolyase family
FHE73_16325	COG0288	reversible hydration of carbon dioxide
FHE73_16335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FHE73_16340	COG5609	conserved protein (DUF2294)
FHE73_16355	COG0697	spore germination
FHE73_16370	COG0456	acetyltransferase
FHE73_16375	COG1575	Belongs to the MenA family. Type 1 subfamily
FHE73_16380	COG0803	Belongs to the bacterial solute-binding protein 9 family
FHE73_16385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FHE73_16390	COG1121	(ABC) transporter
FHE73_16415	COG0798	PFAM Bile acid sodium symporter
FHE73_16420	COG0346	lactoylglutathione lyase activity
FHE73_16425	COG0640	Transcriptional regulator
FHE73_16445	COG0346	lactoylglutathione lyase activity
FHE73_16475	COG0745	RESPONSE REGULATOR receiver
FHE73_16480	COG5002	protein histidine kinase activity
FHE73_16480	COG3850	Histidine kinase
FHE73_16510	COG2197	response regulator
FHE73_16545	COG2814	Major facilitator Superfamily
FHE73_16560	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FHE73_16575	COG1690	Belongs to the RtcB family
FHE73_16585	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FHE73_16600	COG1136	(ABC) transporter
FHE73_16605	COG0577	efflux transmembrane transporter activity
FHE73_16630	COG5002	protein histidine kinase activity
FHE73_16630	COG3850	Histidine kinase
FHE73_16640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_16665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FHE73_16685	COG0662	Cupin 2, conserved barrel domain protein
FHE73_16695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_16695	COG2207	Transcriptional regulator
FHE73_16715	COG5632	N-Acetylmuramoyl-L-alanine amidase
FHE73_16715	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_16730	COG2814	Major facilitator Superfamily
FHE73_16810	COG1876	peptidase activity
FHE73_16815	COG2843	Capsule synthesis protein
FHE73_16825	COG0477	Major facilitator Superfamily
FHE73_16840	COG1846	Transcriptional regulator
FHE73_16845	COG2814	Major facilitator Superfamily
FHE73_16855	COG2031	fatty acid transporter
FHE73_16870	COG2249	NAD(P)H dehydrogenase (quinone) activity
FHE73_16925	COG1288	antiporter activity
FHE73_16930	COG2356	endonuclease I
FHE73_16935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FHE73_16955	COG1733	regulation of RNA biosynthetic process
FHE73_16960	COG0778	Nitroreductase
FHE73_16990	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_17000	COG1131	(ABC) transporter
FHE73_17030	COG1011	Hydrolase
FHE73_17060	COG0180	Tryptophanyl-tRNA synthetase
FHE73_17070	COG0628	permease
FHE73_17120	COG1253	flavin adenine dinucleotide binding
FHE73_17125	COG0789	Transcriptional regulator
FHE73_17135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FHE73_17160	COG0697	spore germination
FHE73_17165	COG1357	PFAM Pentapeptide repeats (8 copies)
FHE73_17175	COG2706	6-phosphogluconolactonase activity
FHE73_17180	COG1070	Carbohydrate kinase
FHE73_17190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FHE73_17195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FHE73_17200	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FHE73_17205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FHE73_17235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHE73_17235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHE73_17240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FHE73_17245	COG1733	regulation of RNA biosynthetic process
FHE73_17275	COG0814	amino acid
FHE73_17305	COG2188	Transcriptional regulator
FHE73_17310	COG0673	inositol 2-dehydrogenase activity
FHE73_17330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_17350	COG0384	phenazine biosynthesis protein PhzF
FHE73_17370	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_17375	COG2249	NAD(P)H dehydrogenase (quinone) activity
FHE73_17380	COG1733	regulation of RNA biosynthetic process
FHE73_17385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FHE73_17405	COG0726	polysaccharide deacetylase
FHE73_17415	COG1191	sigma factor activity
FHE73_17470	COG1151	hydroxylamine reductase activity
FHE73_17505	COG2072	flavoprotein involved in K transport
FHE73_17540	COG0604	alcohol dehydrogenase
FHE73_17545	COG1113	amino acid transport
FHE73_17550	COG2814	Major facilitator Superfamily
FHE73_17585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FHE73_17590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FHE73_17605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_17610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_17615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_17620	COG3739	integral membrane protein
FHE73_17650	COG0583	DNA-binding transcription factor activity
FHE73_17670	COG1193	negative regulation of DNA recombination
FHE73_17685	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FHE73_17690	COG1164	Oligoendopeptidase f
FHE73_17695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FHE73_17720	COG0584	glycerophosphoryl diester phosphodiesterase
FHE73_17730	COG0640	Transcriptional regulator
FHE73_17735	COG0604	alcohol dehydrogenase
FHE73_17745	COG0457	Tetratricopeptide repeat
FHE73_17755	COG2808	Putative FMN-binding domain
FHE73_17770	COG0385	Bile acid
FHE73_17775	COG0277	FAD linked oxidase domain protein
FHE73_17800	COG0457	Tetratricopeptide repeat
FHE73_17830	COG2205	protein histidine kinase activity
FHE73_17835	COG0745	RESPONSE REGULATOR receiver
FHE73_17855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FHE73_17865	COG2814	Major facilitator Superfamily
FHE73_17940	COG3852	Histidine kinase
FHE73_17950	COG1285	pathogenesis
FHE73_17960	COG2514	catechol 2,3-dioxygenase activity
FHE73_17965	COG2720	vancomycin resistance protein
FHE73_17990	COG1278	Cold shock
FHE73_18000	COG0716	FMN binding
FHE73_18010	COG1051	belongs to the nudix hydrolase family
FHE73_18030	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_18040	COG0165	Argininosuccinate lyase
FHE73_18055	COG4145	pantothenate transmembrane transporter activity
FHE73_18065	COG1012	belongs to the aldehyde dehydrogenase family
FHE73_18070	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_18080	COG1657	PFAM Prenyltransferase squalene oxidase
FHE73_18085	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FHE73_18090	COG2962	Rard protein
FHE73_18095	COG3326	Membrane
FHE73_18110	COG0489	protein tyrosine kinase activity
FHE73_18120	COG0314	molybdopterin synthase activity
FHE73_18125	COG0303	'Molybdopterin
FHE73_18130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FHE73_18135	COG2116	formate transmembrane transporter activity
FHE73_18145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FHE73_18150	COG5609	conserved protein (DUF2294)
FHE73_18155	COG2427	Protein of unknown function (DUF1641)
FHE73_18160	COG3383	formate dehydrogenase (NAD+) activity
FHE73_18165	COG0697	spore germination
FHE73_18210	COG2226	methyltransferase
FHE73_18215	COG4166	transmembrane transport
FHE73_18220	COG4166	transmembrane transport
FHE73_18225	COG4166	transmembrane transport
FHE73_18230	COG1301	dicarboxylic acid transport
FHE73_18235	COG1316	TRANSCRIPTIONal
FHE73_18245	COG1595	DNA-templated transcription, initiation
FHE73_18255	COG1131	(ABC) transporter
FHE73_18265	COG0673	inositol 2-dehydrogenase activity
FHE73_18270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHE73_18275	COG0187	DNA topoisomerase II activity
FHE73_18280	COG1832	CoA-binding protein
FHE73_18285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHE73_18290	COG0745	RESPONSE REGULATOR receiver
FHE73_18310	COG4841	protein insertion into membrane
FHE73_18315	COG0824	Thioesterase
FHE73_18345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHE73_18360	COG1132	(ABC) transporter
FHE73_18365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FHE73_18375	COG0726	polysaccharide deacetylase
FHE73_18395	COG2211	Major facilitator Superfamily
FHE73_18405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHE73_18420	COG0183	Belongs to the thiolase family
FHE73_18425	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_18430	COG1268	BioY protein
FHE73_18435	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_18450	COG1396	sequence-specific DNA binding
FHE73_18495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_18510	COG5002	protein histidine kinase activity
FHE73_18515	COG0400	carboxylic ester hydrolase activity
FHE73_18520	COG0346	lactoylglutathione lyase activity
FHE73_18525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHE73_18535	COG0069	glutamate synthase activity
FHE73_18540	COG1902	pentaerythritol trinitrate reductase activity
FHE73_18545	COG1329	Transcriptional regulator
FHE73_18550	COG0010	Belongs to the arginase family
FHE73_18575	COG2226	methyltransferase
FHE73_18605	COG4846	Membrane protein involved in cytochrome C biogenesis
FHE73_18610	COG0785	Cytochrome C biogenesis protein
FHE73_18640	COG1131	(ABC) transporter
FHE73_18655	COG0583	DNA-binding transcription factor activity
FHE73_18665	COG1346	cytolysis
FHE73_18670	COG0494	nUDIX hydrolase
FHE73_18680	COG0730	response to heat
FHE73_18705	COG1132	(ABC) transporter
FHE73_18710	COG1132	(ABC) transporter
FHE73_18735	COG3639	organic phosphonate transmembrane transporter activity
FHE73_18750	COG0737	Belongs to the 5'-nucleotidase family
FHE73_18760	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FHE73_18780	COG1695	Transcriptional regulator
FHE73_18790	COG1388	LysM domain
FHE73_18790	COG5632	N-Acetylmuramoyl-L-alanine amidase
FHE73_18790	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_18795	COG0739	heme binding
FHE73_18800	COG0741	lytic transglycosylase activity
FHE73_18835	COG0174	glutamine synthetase
FHE73_18840	COG0789	Transcriptional regulator
FHE73_18845	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FHE73_18850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHE73_18855	COG2860	membrane
FHE73_18860	COG0464	growth
FHE73_18890	COG1388	LysM domain
FHE73_18890	COG3584	3D domain protein
FHE73_18895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHE73_18895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHE73_18895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHE73_18900	COG1105	Belongs to the carbohydrate kinase PfkB family
FHE73_18905	COG1349	DNA-binding transcription factor activity
FHE73_18910	COG1979	alcohol dehydrogenase
FHE73_18915	COG2322	membrane
FHE73_18925	COG1113	amino acid transport
FHE73_18940	COG1473	amidohydrolase
FHE73_18945	COG1408	metallophosphoesterase
FHE73_18950	COG2116	formate transmembrane transporter activity
FHE73_18965	COG2217	Heavy metal translocating P-type atpase
FHE73_18970	COG2608	mercury ion transmembrane transporter activity
FHE73_18975	COG1937	Protein conserved in bacteria
FHE73_18985	COG2819	hydrolase of the alpha beta superfamily
FHE73_18990	COG1120	ATPase activity
FHE73_18995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_19000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_19005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_19010	COG0708	Exodeoxyribonuclease III
FHE73_19015	COG2169	Transcriptional regulator
FHE73_19020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHE73_19025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FHE73_19035	COG2364	Membrane
FHE73_19050	COG2267	carboxylic ester hydrolase activity
FHE73_19055	COG3300	MHYT domain
FHE73_19055	COG5001	Diguanylate cyclase
FHE73_19075	COG1086	Polysaccharide biosynthesis protein
FHE73_19095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_19110	COG0840	transmembrane signaling receptor activity
FHE73_19120	COG1404	Belongs to the peptidase S8 family
FHE73_19125	COG3773	Cell wall hydrolase
FHE73_19140	COG1368	sulfuric ester hydrolase activity
FHE73_19145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FHE73_19170	COG4550	Control of competence regulator ComK, YlbF/YmcA
FHE73_19185	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHE73_19190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FHE73_19190	COG0674	pyruvate-flavodoxin oxidoreductase activity
FHE73_19200	COG2359	stage V sporulation protein S
FHE73_19205	COG1692	metallophosphoesterase
FHE73_19225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FHE73_19230	COG1426	Protein conserved in bacteria
FHE73_19245	COG0300	oxidoreductase activity
FHE73_19250	COG0612	Peptidase, M16
FHE73_19255	COG0612	Peptidase, M16
FHE73_19280	COG2188	Transcriptional regulator
FHE73_19305	COG0740	serine-type endopeptidase activity
FHE73_19310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FHE73_19320	COG0527	aspartate kinase activity
FHE73_19325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHE73_19330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FHE73_19350	COG4824	toxin secretion phage lysis holin
FHE73_19465	COG1278	Cold shock
FHE73_19470	COG0582	viral genome integration into host DNA
FHE73_19520	COG0305	Participates in initiation and elongation during chromosome replication
FHE73_19555	COG1396	sequence-specific DNA binding
FHE73_19585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHE73_19590	COG1873	PFAM PRC-barrel domain
FHE73_19595	COG0612	Peptidase, M16
FHE73_19600	COG0726	polysaccharide deacetylase
FHE73_19615	COG0196	riboflavin kinase activity
FHE73_19630	COG1550	Protein conserved in bacteria
FHE73_19640	COG1358	cellular component organization or biogenesis
FHE73_19645	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FHE73_19650	COG0195	Participates in both transcription termination and antitermination
FHE73_19670	COG0750	zinc metalloprotease
FHE73_19680	COG4589	Belongs to the CDS family
FHE73_19725	COG4974	Belongs to the 'phage' integrase family
FHE73_19735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FHE73_19740	COG0758	DNA mediated transformation
FHE73_19745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FHE73_19785	COG1837	Belongs to the UPF0109 family
FHE73_19795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FHE73_19805	COG0552	protein localization to endoplasmic reticulum
FHE73_19810	COG1196	nuclear chromosome segregation
FHE73_19825	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_19830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FHE73_19845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FHE73_19850	COG1461	Dihydroxyacetone kinase
FHE73_19855	COG1302	Protein conserved in bacteria
FHE73_19870	COG1564	THIamine pyrophosphokinase
FHE73_19875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FHE73_19885	COG2815	serine threonine protein kinase
FHE73_19885	COG0515	serine threonine protein kinase
FHE73_19890	COG0631	protein serine/threonine phosphatase activity
FHE73_19900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FHE73_19900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHE73_19915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHE73_19920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FHE73_19940	COG1561	YicC-like family, N-terminal region
FHE73_19945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHE73_19960	COG0006	proline dipeptidase activity
FHE73_19980	COG3069	C4-dicarboxylate transmembrane transporter activity
FHE73_20040	COG0564	pseudouridine synthase activity
FHE73_20060	COG3599	regulation of cell shape
FHE73_20065	COG2302	S4 RNA-binding domain
FHE73_20070	COG0762	integral membrane protein
FHE73_20080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FHE73_20090	COG1873	PFAM PRC-barrel domain
FHE73_20095	COG1191	sigma factor activity
FHE73_20100	COG1191	sigma factor activity
FHE73_20110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FHE73_20115	COG0849	cell division
FHE73_20135	COG0772	Belongs to the SEDS family
FHE73_20155	COG0768	penicillin binding
FHE73_20180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FHE73_20200	COG1399	metal-binding, possibly nucleic acid-binding protein
FHE73_20375	COG0582	viral genome integration into host DNA
FHE73_20445	COG1484	DNA-dependent DNA replication
FHE73_20470	COG1396	sequence-specific DNA binding
FHE73_20480	COG1396	sequence-specific DNA binding
FHE73_20490	COG0582	viral genome integration into host DNA
FHE73_20500	COG3480	Lon protease (S16) C-terminal proteolytic domain
FHE73_20505	COG1752	Esterase of the alpha-beta hydrolase superfamily
FHE73_20510	COG3314	Sporulation integral membrane protein YlbJ
FHE73_20520	COG0742	ribosomal rna small subunit methyltransferase
FHE73_20535	COG3679	Belongs to the UPF0342 family
FHE73_20540	COG0406	alpha-ribazole phosphatase activity
FHE73_20555	COG2340	Cysteine-rich secretory protein family
FHE73_20570	COG3336	cytochrome c oxidase
FHE73_20605	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FHE73_20615	COG0772	Belongs to the SEDS family
FHE73_20625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FHE73_20630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FHE73_20640	COG4896	Protein conserved in bacteria
FHE73_20665	COG0483	inositol monophosphate 1-phosphatase activity
FHE73_20685	COG1982	Orn Lys Arg decarboxylase major
FHE73_20735	COG0022	dehydrogenase e1 component
FHE73_20740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FHE73_20755	COG0561	phosphatase activity
FHE73_20770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FHE73_20775	COG0569	domain protein
FHE73_20795	COG0583	DNA-binding transcription factor activity
FHE73_20800	COG0517	IMP dehydrogenase activity
FHE73_20810	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FHE73_20815	COG4703	Protein of unknown function (DUF1797)
FHE73_20830	COG2200	EAL domain
FHE73_20835	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_20840	COG1408	metallophosphoesterase
FHE73_20885	COG2814	Major facilitator Superfamily
FHE73_20905	COG3209	COG3209 Rhs family protein
FHE73_20915	COG2205	protein histidine kinase activity
FHE73_20925	COG0436	Aminotransferase
FHE73_20930	COG1609	Transcriptional regulator
FHE73_20935	COG3833	ABC-type maltose transport systems, permease component
FHE73_20940	COG1175	transmembrane transport
FHE73_20945	COG2182	Extracellular solute-binding protein
FHE73_20955	COG0366	Alpha amylase catalytic
FHE73_20960	COG3842	ATPase activity
FHE73_21000	COG0183	Belongs to the thiolase family
FHE73_21035	COG1695	Transcriptional regulator
FHE73_21040	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_21060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FHE73_21065	COG0436	Aminotransferase
FHE73_21100	COG2084	Dehydrogenase
FHE73_21110	COG2203	Gaf domain
FHE73_21110	COG2199	diguanylate cyclase activity
FHE73_21115	COG0778	Nitroreductase
FHE73_21140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHE73_21140	COG2190	(PTS) system
FHE73_21140	COG1263	PTS System
FHE73_21145	COG3711	transcriptional antiterminator
FHE73_21165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FHE73_21195	COG1547	Domain of unknown function (DUF309)
FHE73_21205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FHE73_21210	COG4086	secreted protein
FHE73_21215	COG0561	phosphatase activity
FHE73_21220	COG0697	spore germination
FHE73_21235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHE73_21260	COG0733	neurotransmitter:sodium symporter activity
FHE73_21280	COG1686	Belongs to the peptidase S11 family
FHE73_21290	COG1725	Transcriptional regulator
FHE73_21295	COG1131	(ABC) transporter
FHE73_21310	COG1846	Transcriptional regulator
FHE73_21325	COG0598	Magnesium transport protein CorA
FHE73_21350	COG4974	Belongs to the 'phage' integrase family
FHE73_21360	COG0735	belongs to the Fur family
FHE73_21365	COG1300	Membrane
FHE73_21385	COG0667	Aldo Keto reductase
FHE73_21390	COG0656	L-ascorbic acid biosynthetic process
FHE73_21395	COG0456	acetyltransferase
FHE73_21395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FHE73_21405	COG1525	nuclease
FHE73_21405	COG0737	Belongs to the 5'-nucleotidase family
FHE73_21405	COG4085	toxin activity
FHE73_21415	COG0596	Alpha beta hydrolase
FHE73_21420	COG2056	Na+-H+ antiporter family
FHE73_21425	COG1609	Transcriptional regulator
FHE73_21430	COG0456	acetyltransferase
FHE73_21435	COG1073	alpha beta
FHE73_21455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHE73_21455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHE73_21460	COG0307	riboflavin synthase, alpha
FHE73_21490	COG1073	alpha beta
FHE73_21490	COG2226	methyltransferase
FHE73_21505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FHE73_21520	COG0737	Belongs to the 5'-nucleotidase family
FHE73_21530	COG1522	sequence-specific DNA binding
FHE73_21575	COG0300	oxidoreductase activity
FHE73_21580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_21585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHE73_21590	COG1760	l-serine dehydratase
FHE73_21595	COG1760	l-serine dehydratase
FHE73_21630	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHE73_21635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_21645	COG1376	ErfK ybiS ycfS ynhG family protein
FHE73_21650	COG4129	membrane
FHE73_21655	COG1126	abc transporter atp-binding protein
FHE73_21660	COG0765	amino acid transport
FHE73_21665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHE73_21685	COG2323	membrane
FHE73_21690	COG0772	Belongs to the SEDS family
FHE73_21695	COG0508	dehydrogenase complex catalyzes the overall conversion of
FHE73_21700	COG0022	dehydrogenase e1 component
FHE73_21705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FHE73_21710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FHE73_21720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FHE73_21725	COG0280	phosphate acetyltransferase
FHE73_21735	COG3829	transcription factor binding
FHE73_21735	COG3290	protein histidine kinase activity
FHE73_21745	COG0584	glycerophosphoryl diester phosphodiesterase
FHE73_21750	COG3093	addiction module antidote protein HigA
FHE73_21770	COG0750	zinc metalloprotease
FHE73_21775	COG0497	DNA recombination
FHE73_21785	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FHE73_21795	COG0142	geranyltranstransferase activity
FHE73_21820	COG1302	Protein conserved in bacteria
FHE73_21825	COG0439	Biotin carboxylase
FHE73_21830	COG0511	ligase activity, forming carbon-carbon bonds
FHE73_21875	COG3854	ATPases associated with a variety of cellular activities
FHE73_21900	COG0006	proline dipeptidase activity
FHE73_21915	COG3872	metal-dependent enzyme
FHE73_21925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHE73_21960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHE73_21970	COG1609	Transcriptional regulator
FHE73_21980	COG2076	Multidrug Resistance protein
FHE73_21985	COG2076	Multidrug Resistance protein
FHE73_22020	COG1725	Transcriptional regulator
FHE73_22055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FHE73_22120	COG1459	type II secretion system
FHE73_22125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FHE73_22180	COG0646	methionine synthase
FHE73_22180	COG1410	methionine synthase
FHE73_22185	COG0646	methionine synthase
FHE73_22185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FHE73_22190	COG0626	cystathionine gamma-synthase activity
FHE73_22195	COG0626	cystathionine gamma-synthase activity
FHE73_22215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_22225	COG1940	carbohydrate kinase activity
FHE73_22230	COG4483	Protein conserved in bacteria
FHE73_22235	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FHE73_22245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FHE73_22250	COG0704	Plays a role in the regulation of phosphate uptake
FHE73_22260	COG0573	inorganic phosphate transmembrane transporter activity
FHE73_22265	COG0573	inorganic phosphate transmembrane transporter activity
FHE73_22270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FHE73_22280	COG0477	Major facilitator Superfamily
FHE73_22285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHE73_22295	COG5521	maltodextrose utilization protein MalA
FHE73_22310	COG0735	belongs to the Fur family
FHE73_22315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FHE73_22320	COG1121	(ABC) transporter
FHE73_22325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_22355	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FHE73_22360	COG2384	SAM-dependent methyltransferase
FHE73_22370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHE73_22375	COG0358	DNA primase activity
FHE73_22385	COG0517	IMP dehydrogenase activity
FHE73_22400	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FHE73_22405	COG0295	cytidine deaminase activity
FHE73_22410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FHE73_22420	COG1480	7TM receptor with intracellular HD hydrolase
FHE73_22425	COG1702	phosphate starvation-inducible protein PhoH
FHE73_22445	COG1610	YqeY-like protein
FHE73_22455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHE73_22460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FHE73_22480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FHE73_22490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHE73_22495	COG1733	regulation of RNA biosynthetic process
FHE73_22520	COG1466	dna polymerase III delta subunit
FHE73_22535	COG2131	deaminase
FHE73_22540	COG1596	polysaccharide export
FHE73_22540	COG1555	photosystem II stabilization
FHE73_22545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHE73_22550	COG2226	methyltransferase
FHE73_22555	COG0799	negative regulation of ribosome biogenesis
FHE73_22560	COG1713	HD superfamily hydrolase involved in NAD metabolism
FHE73_22570	COG1534	Rna-binding protein
FHE73_22580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FHE73_22585	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FHE73_22600	COG1191	sigma factor activity
FHE73_22610	COG1595	DNA-templated transcription, initiation
FHE73_22620	COG0778	Nitroreductase
FHE73_22625	COG2357	RelA SpoT domain protein
FHE73_22635	COG1785	Belongs to the alkaline phosphatase family
FHE73_22645	COG2267	carboxylic ester hydrolase activity
FHE73_22680	COG1404	Belongs to the peptidase S8 family
FHE73_22685	COG3186	Phenylalanine-4-hydroxylase
FHE73_22695	COG2514	catechol 2,3-dioxygenase activity
FHE73_22700	COG2259	Doxx family
FHE73_22740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_22755	COG1012	belongs to the aldehyde dehydrogenase family
FHE73_22755	COG1454	alcohol dehydrogenase
FHE73_22760	COG0626	cystathionine gamma-synthase activity
FHE73_22765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHE73_22790	COG0768	penicillin binding
FHE73_22825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FHE73_22855	COG0628	permease
FHE73_22875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FHE73_22890	COG1104	cysteine desulfurase activity
FHE73_22895	COG1959	2 iron, 2 sulfur cluster binding
FHE73_22900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FHE73_22915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FHE73_22945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHE73_22955	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FHE73_22955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FHE73_22960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FHE73_22965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FHE73_22965	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FHE73_22975	COG2244	polysaccharide biosynthetic process
FHE73_22980	COG2323	membrane
FHE73_22990	COG1862	Preprotein translocase
FHE73_23020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FHE73_23050	COG0157	Belongs to the NadC ModD family
FHE73_23055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FHE73_23060	COG1104	cysteine desulfurase activity
FHE73_23065	COG1827	regulation of RNA biosynthetic process
FHE73_23070	COG2258	MOSC domain
FHE73_23080	COG0077	Prephenate dehydratase
FHE73_23085	COG0577	efflux transmembrane transporter activity
FHE73_23090	COG0577	efflux transmembrane transporter activity
FHE73_23095	COG1136	(ABC) transporter
FHE73_23100	COG5002	protein histidine kinase activity
FHE73_23105	COG0745	RESPONSE REGULATOR receiver
FHE73_23115	COG3290	protein histidine kinase activity
FHE73_23130	COG1530	ribonuclease E activity
FHE73_23135	COG1994	Peptidase M50
FHE73_23140	COG0739	heme binding
FHE73_23145	COG2894	cell division
FHE73_23160	COG1792	Involved in formation and maintenance of cell shape
FHE73_23165	COG1077	Cell shape determining protein MreB Mrl
FHE73_23185	COG0285	dihydrofolate synthase activity
FHE73_23200	COG1388	LysM domain
FHE73_23210	COG0113	porphobilinogen synthase activity
FHE73_23215	COG1587	Uroporphyrinogen-III synthase
FHE73_23225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FHE73_23235	COG1846	Transcriptional regulator
FHE73_23240	COG1764	response to oxidative stress
FHE73_23255	COG1067	ATP-dependent peptidase activity
FHE73_23255	COG0470	DNA polymerase III
FHE73_23335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FHE73_23350	COG0622	Phosphoesterase
FHE73_23365	COG5401	PFAM Sporulation and spore germination
FHE73_23385	COG1309	transcriptional regulator
FHE73_23400	COG2197	response regulator
FHE73_23405	COG2233	PERMEase
FHE73_23410	COG0402	S-adenosylhomocysteine deaminase activity
FHE73_23415	COG1983	PspC domain protein
FHE73_23420	COG1396	sequence-specific DNA binding
FHE73_23425	COG0697	spore germination
FHE73_23435	COG1959	2 iron, 2 sulfur cluster binding
FHE73_23440	COG1668	transmembrane transport
FHE73_23445	COG4152	abc transporter atp-binding protein
FHE73_23450	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FHE73_23455	COG1360	Flagellar Motor Protein
FHE73_23460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FHE73_23465	COG1876	peptidase activity
FHE73_23470	COG0824	Thioesterase
FHE73_23475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FHE73_23480	COG1053	succinate dehydrogenase
FHE73_23485	COG2009	succinate dehydrogenase
FHE73_23490	COG1719	4-vinyl reductase, 4VR
FHE73_23500	COG3118	belongs to the thioredoxin family
FHE73_23505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FHE73_23510	COG2086	electron transfer activity
FHE73_23515	COG1024	Enoyl-CoA hydratase
FHE73_23520	COG1309	transcriptional regulator
FHE73_23525	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_23545	COG2318	DinB family
FHE73_23570	COG1131	(ABC) transporter
FHE73_23575	COG2205	protein histidine kinase activity
FHE73_23580	COG0745	RESPONSE REGULATOR receiver
FHE73_23585	COG4895	conserved protein (DUF2196)
FHE73_23590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FHE73_23605	COG4509	Sortase family
FHE73_23610	COG1120	ATPase activity
FHE73_23625	COG5386	Cell surface protein
FHE73_23635	COG5386	Cell surface protein
FHE73_23640	COG1114	Component of the transport system for branched-chain amino acids
FHE73_23645	COG1187	pseudouridine synthase activity
FHE73_23655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FHE73_23655	COG1796	DNA polymerase
FHE73_23660	COG1286	toxin biosynthetic process
FHE73_23705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHE73_23715	COG1418	mRNA catabolic process
FHE73_23735	COG2814	Major facilitator Superfamily
FHE73_23740	COG1566	PFAM secretion protein HlyD family protein
FHE73_23745	COG1309	transcriptional regulator
FHE73_23750	COG1363	Peptidase, m42
FHE73_23775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHE73_23790	COG1484	DNA-dependent DNA replication
FHE73_23795	COG3611	Membrane attachment protein
FHE73_23805	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FHE73_23810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FHE73_23820	COG1971	Probably functions as a manganese efflux pump
FHE73_23830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHE73_23830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHE73_23835	COG5002	protein histidine kinase activity
FHE73_23840	COG0745	RESPONSE REGULATOR receiver
FHE73_23860	COG0538	isocitrate dehydrogenase activity
FHE73_23865	COG0372	Belongs to the citrate synthase family
FHE73_23880	COG0628	permease
FHE73_23885	COG3030	protein affecting phage T7 exclusion by the F plasmid
FHE73_23910	COG1725	Transcriptional regulator
FHE73_23915	COG0281	malic enzyme
FHE73_23920	COG0587	DNA-directed DNA polymerase activity
FHE73_23935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FHE73_23955	COG4109	DRTGG domain
FHE73_23965	COG0006	proline dipeptidase activity
FHE73_24010	COG0662	Cupin 2, conserved barrel domain protein
FHE73_24025	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_24030	COG0589	response to stress
FHE73_24075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_24100	COG0827	DNA restriction-modification system
FHE73_24105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FHE73_24110	COG3874	Sporulation protein YtfJ
FHE73_24135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FHE73_24150	COG1104	cysteine desulfurase activity
FHE73_24160	COG0583	DNA-binding transcription factor activity
FHE73_24165	COG0697	spore germination
FHE73_24170	COG1309	transcriptional regulator
FHE73_24175	COG1956	GAF domain-containing protein
FHE73_24180	COG0626	cystathionine gamma-synthase activity
FHE73_24210	COG0110	maltose O-acetyltransferase activity
FHE73_24220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FHE73_24225	COG0454	-acetyltransferase
FHE73_24230	COG0517	IMP dehydrogenase activity
FHE73_24235	COG0123	including yeast histone deacetylase and acetoin utilization protein
FHE73_24240	COG2267	carboxylic ester hydrolase activity
FHE73_24250	COG0745	RESPONSE REGULATOR receiver
FHE73_24260	COG0666	response to abiotic stimulus
FHE73_24290	COG1609	Transcriptional regulator
FHE73_24295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FHE73_24295	COG1605	Chorismate mutase
FHE73_24300	COG4851	CamS sex pheromone cAM373 precursor
FHE73_24305	COG3118	belongs to the thioredoxin family
FHE73_24315	COG2309	aminopeptidase activity
FHE73_24330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_24345	COG1674	ftsk spoiiie
FHE73_24350	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHE73_24350	COG1388	LysM domain
FHE73_24360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHE73_24370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHE73_24375	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FHE73_24380	COG1363	Peptidase, m42
FHE73_24390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_24405	COG0510	thiamine kinase activity
FHE73_24410	COG1523	belongs to the glycosyl hydrolase 13 family
FHE73_24420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHE73_24425	COG1349	DNA-binding transcription factor activity
FHE73_24430	COG1187	pseudouridine synthase activity
FHE73_24435	COG2244	polysaccharide biosynthetic process
FHE73_24440	COG2081	HI0933 family
FHE73_24445	COG2814	Major facilitator Superfamily
FHE73_24455	COG3832	glyoxalase III activity
FHE73_24480	COG1329	Transcriptional regulator
FHE73_24505	COG0314	molybdopterin synthase activity
FHE73_24510	COG1763	Mo-molybdopterin cofactor biosynthetic process
FHE73_24515	COG0303	'Molybdopterin
FHE73_24525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FHE73_24530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FHE73_24555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FHE73_24565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FHE73_24605	COG2814	Major facilitator Superfamily
FHE73_24610	COG0475	glutathione-regulated potassium exporter activity
FHE73_24615	COG0490	domain, Protein
FHE73_24620	COG0582	viral genome integration into host DNA
FHE73_24635	COG1136	(ABC) transporter
FHE73_24655	COG1242	4 iron, 4 sulfur cluster binding
FHE73_24660	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FHE73_24670	COG1794	racemase activity, acting on amino acids and derivatives
FHE73_24690	COG2267	carboxylic ester hydrolase activity
FHE73_24695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FHE73_24700	COG0671	phosphoesterase, PA-phosphatase related
FHE73_24705	COG0438	transferase activity, transferring glycosyl groups
FHE73_24770	COG5002	protein histidine kinase activity
FHE73_24775	COG3852	Histidine kinase
FHE73_24780	COG2267	carboxylic ester hydrolase activity
FHE73_24785	COG1368	sulfuric ester hydrolase activity
FHE73_24795	COG4895	conserved protein (DUF2196)
FHE73_24810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FHE73_24815	COG1116	anion transmembrane transporter activity
FHE73_24820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FHE73_24845	COG0494	nUDIX hydrolase
FHE73_24880	COG2076	Multidrug Resistance protein
FHE73_24885	COG2076	Multidrug Resistance protein
FHE73_24890	COG0789	Transcriptional regulator
FHE73_24905	COG0288	reversible hydration of carbon dioxide
FHE73_24915	COG1271	oxidase subunit
FHE73_24920	COG1294	oxidase, subunit
FHE73_24935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_24955	COG1842	Phage shock protein A
FHE73_24985	COG5002	protein histidine kinase activity
FHE73_24990	COG0745	RESPONSE REGULATOR receiver
FHE73_25020	COG1597	lipid kinase activity
FHE73_25045	COG0586	Pfam SNARE associated Golgi protein
FHE73_25055	COG0577	efflux transmembrane transporter activity
FHE73_25060	COG1136	(ABC) transporter
FHE73_25065	COG3708	Transcriptional regulator
FHE73_25065	COG2207	Transcriptional regulator
FHE73_25075	COG1131	(ABC) transporter
FHE73_25080	COG5658	integral membrane protein
FHE73_25085	COG0640	Transcriptional regulator
FHE73_25095	COG0745	RESPONSE REGULATOR receiver
FHE73_25100	COG2205	protein histidine kinase activity
FHE73_25105	COG0577	efflux transmembrane transporter activity
FHE73_25110	COG0577	efflux transmembrane transporter activity
FHE73_25115	COG1136	(ABC) transporter
FHE73_25120	COG0577	efflux transmembrane transporter activity
FHE73_25155	COG3964	amidohydrolase
FHE73_25180	COG4948	Mandelate Racemase Muconate Lactonizing
FHE73_25190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FHE73_25195	COG0596	Alpha beta hydrolase
FHE73_25205	COG1169	isochorismate synthase
FHE73_25210	COG1575	Belongs to the MenA family. Type 1 subfamily
FHE73_25215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FHE73_25220	COG1278	Cold shock
FHE73_25235	COG0058	SHG alpha-glucan phosphorylase activity
FHE73_25245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FHE73_25275	COG0039	L-malate dehydrogenase activity
FHE73_25375	COG0544	peptidyl-prolyl cis-trans isomerase activity
FHE73_25410	COG1285	pathogenesis
FHE73_25415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FHE73_25435	COG2155	Conserved Protein
FHE73_25440	COG1098	S1 RNA binding domain
FHE73_25445	COG0436	Aminotransferase
FHE73_25450	COG1522	sequence-specific DNA binding
FHE73_25455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHE73_25460	COG2267	carboxylic ester hydrolase activity
FHE73_25470	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FHE73_25485	COG5018	Exonuclease
FHE73_25490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FHE73_25505	COG0423	glycine-tRNA ligase activity
FHE73_25510	COG2050	protein possibly involved in aromatic compounds catabolism
FHE73_25520	COG1268	BioY protein
FHE73_25525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FHE73_25530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHE73_25545	COG3584	3D domain protein
FHE73_25560	COG1252	NADH dehydrogenase
FHE73_25575	COG3708	Transcriptional regulator
FHE73_25590	COG1683	Conserved Protein
FHE73_25615	COG0316	Belongs to the HesB IscA family
FHE73_25630	COG1252	NADH dehydrogenase
FHE73_25640	COG2274	protein secretion by the type I secretion system
FHE73_25645	COG0390	transport system, permease component
FHE73_25650	COG2824	Alkylphosphonate utilization operon protein PhnA
FHE73_25675	COG4837	Protein of unknown function (DUF1462)
FHE73_25680	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FHE73_25690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FHE73_25695	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FHE73_25710	COG2249	NAD(P)H dehydrogenase (quinone) activity
FHE73_25715	COG0647	UMP catabolic process
FHE73_25725	COG2445	Protein of unknown function DUF86
FHE73_25730	COG1494	fructose-1,6-bisphosphatase
FHE73_25750	COG4470	Protein conserved in bacteria
FHE73_25760	COG0789	Transcriptional regulator
FHE73_25765	COG4377	Putative membrane peptidase family (DUF2324)
FHE73_25790	COG0739	heme binding
FHE73_25800	COG3377	Domain of unknown function (DUF1805)
FHE73_25805	COG0737	Belongs to the 5'-nucleotidase family
FHE73_25815	COG0719	Fe-S assembly protein
FHE73_25820	COG0822	iron-sulfur transferase activity
FHE73_25825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FHE73_25830	COG0719	Fe-S assembly protein
FHE73_25835	COG0396	ATPase activity
FHE73_25840	COG1464	Belongs to the NlpA lipoprotein family
FHE73_25845	COG1464	Belongs to the NlpA lipoprotein family
FHE73_25850	COG2011	ABC-type metal ion transport system permease component
FHE73_25865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHE73_25870	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FHE73_25880	COG1393	Belongs to the ArsC family
FHE73_25900	COG0039	L-malate dehydrogenase activity
FHE73_25925	COG1309	transcriptional regulator
FHE73_25930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHE73_25935	COG1960	acyl-CoA dehydrogenase activity
FHE73_25940	COG0183	Belongs to the thiolase family
FHE73_25945	COG1024	Enoyl-CoA hydratase
FHE73_25945	COG1250	3-hydroxyacyl-CoA dehydrogenase
FHE73_25955	COG1686	Belongs to the peptidase S11 family
FHE73_25970	COG0011	TIGRFAM Protein of
FHE73_25975	COG0840	transmembrane signaling receptor activity
FHE73_25990	COG2814	Major facilitator Superfamily
FHE73_25995	COG0531	amino acid
FHE73_26020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHE73_26065	COG0586	Pfam SNARE associated Golgi protein
FHE73_26075	COG1376	ErfK ybiS ycfS ynhG family protein
FHE73_26080	COG0745	RESPONSE REGULATOR receiver
FHE73_26085	COG5002	protein histidine kinase activity
FHE73_26110	COG0840	transmembrane signaling receptor activity
FHE73_26115	COG0840	transmembrane signaling receptor activity
FHE73_26120	COG2151	metal-sulfur cluster biosynthetic enzyme
FHE73_26125	COG3227	Zinc metalloprotease (Elastase)
FHE73_26145	COG0475	glutathione-regulated potassium exporter activity
FHE73_26150	COG0490	domain, Protein
FHE73_26160	COG1115	amino acid carrier protein
FHE73_26165	COG0783	Belongs to the Dps family
FHE73_26180	COG1611	Belongs to the LOG family
FHE73_26190	COG1528	Iron-storage protein
FHE73_26200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_26205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_26210	COG1115	amino acid carrier protein
FHE73_26215	COG1115	amino acid carrier protein
FHE73_26220	COG2910	NAD(P)H-binding
FHE73_26235	COG0656	L-ascorbic acid biosynthetic process
FHE73_26240	COG2814	Major facilitator Superfamily
FHE73_26245	COG1733	regulation of RNA biosynthetic process
FHE73_26255	COG1252	NADH dehydrogenase
FHE73_26310	COG0488	(ABC) transporter
FHE73_26315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHE73_26325	COG3223	Belongs to the PsiE family
FHE73_26335	COG1335	isochorismatase
FHE73_26340	COG1522	sequence-specific DNA binding
FHE73_26385	COG1063	alcohol dehydrogenase
FHE73_26395	COG2124	cytochrome p450
FHE73_26405	COG2124	cytochrome p450
FHE73_26410	COG1309	transcriptional regulator
FHE73_26420	COG1309	transcriptional regulator
FHE73_26455	COG0557	exoribonuclease II activity
FHE73_26460	COG1647	Serine aminopeptidase, S33
FHE73_26465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FHE73_26470	COG1346	cytolysis
FHE73_26505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FHE73_26520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FHE73_26545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHE73_26560	COG2323	membrane
FHE73_26580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHE73_26590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FHE73_26600	COG1051	belongs to the nudix hydrolase family
FHE73_26610	COG0492	ferredoxin-NADP+ reductase activity
FHE73_26615	COG0457	Tetratricopeptide repeat
FHE73_26620	COG0110	maltose O-acetyltransferase activity
FHE73_26640	COG1950	PFAM Membrane protein of
FHE73_26650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FHE73_26670	COG0789	Transcriptional regulator
FHE73_26690	COG0583	DNA-binding transcription factor activity
FHE73_26700	COG0655	NAD(P)H dehydrogenase (quinone) activity
FHE73_26715	COG1132	(ABC) transporter
FHE73_26720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHE73_26725	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_26725	COG0793	Belongs to the peptidase S41A family
FHE73_26730	COG2177	Part of the ABC transporter FtsEX involved in
FHE73_26735	COG2884	Cell division ATP-binding protein ftsE
FHE73_26760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FHE73_26765	COG1278	Cold shock
FHE73_26770	COG1040	competence protein
FHE73_26800	COG5632	N-Acetylmuramoyl-L-alanine amidase
FHE73_26800	COG1388	LysM domain
FHE73_26800	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_26805	COG4824	toxin secretion phage lysis holin
FHE73_26910	COG1598	PFAM Uncharacterised protein family UPF0150
FHE73_27010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FHE73_27020	COG0791	NLP P60 protein
FHE73_27020	COG1388	LysM domain
FHE73_27025	COG1733	regulation of RNA biosynthetic process
FHE73_27030	COG1307	EDD domain protein, DegV family
FHE73_27035	COG1739	Uncharacterized protein family UPF0029
FHE73_27040	COG1316	TRANSCRIPTIONal
FHE73_27045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FHE73_27050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FHE73_27055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHE73_27065	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FHE73_27065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FHE73_27085	COG1486	melibiose metabolic process
FHE73_27090	COG1447	Phosphotransferase system cellobiose-specific component IIA
FHE73_27095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHE73_27105	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FHE73_27115	COG1447	Phosphotransferase system cellobiose-specific component IIA
FHE73_27125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHE73_27130	COG1301	dicarboxylic acid transport
FHE73_27145	COG0346	lactoylglutathione lyase activity
FHE73_27150	COG1511	domain protein
FHE73_27155	COG0583	DNA-binding transcription factor activity
FHE73_27160	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FHE73_27165	COG1271	oxidase subunit
FHE73_27170	COG1294	oxidase, subunit
FHE73_27175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FHE73_27185	COG1620	l-lactate permease
FHE73_27195	COG2389	metal-binding protein
FHE73_27210	COG1368	sulfuric ester hydrolase activity
FHE73_27225	COG0791	NLP P60 protein
FHE73_27225	COG1388	LysM domain
FHE73_27230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_27240	COG1215	transferase activity, transferring glycosyl groups
FHE73_27245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FHE73_27255	COG1388	LysM domain
FHE73_27255	COG3584	3D domain protein
FHE73_27280	COG4715	Zinc finger, swim domain protein
FHE73_27285	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FHE73_27315	COG1191	sigma factor activity
FHE73_27325	COG0577	efflux transmembrane transporter activity
FHE73_27330	COG1136	(ABC) transporter
FHE73_27355	COG5002	protein histidine kinase activity
FHE73_27360	COG0745	RESPONSE REGULATOR receiver
FHE73_27365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FHE73_27390	COG1216	Glycosyl transferase, family 2
FHE73_27400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHE73_27420	COG1086	Polysaccharide biosynthesis protein
FHE73_27425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FHE73_27430	COG4464	protein tyrosine phosphatase activity
FHE73_27435	COG0489	protein tyrosine kinase activity
FHE73_27440	COG3944	biosynthesis protein
FHE73_27445	COG0489	protein tyrosine kinase activity
FHE73_27460	COG1609	Transcriptional regulator
FHE73_27470	COG0739	heme binding
FHE73_27485	COG3279	Response regulator of the LytR AlgR family
FHE73_27490	COG2385	sporulation resulting in formation of a cellular spore
FHE73_27505	COG4836	Membrane
FHE73_27510	COG1007	ATP synthesis coupled electron transport
FHE73_27515	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FHE73_27520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FHE73_27530	COG0839	Belongs to the complex I subunit 6 family
FHE73_27550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FHE73_27565	COG3300	MHYT domain
FHE73_27565	COG5001	Diguanylate cyclase
FHE73_27620	COG0356	it plays a direct role in the translocation of protons across the membrane
FHE73_27655	COG0698	ribose 5-phosphate isomerase
FHE73_27670	COG2259	Doxx family
FHE73_27675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FHE73_27690	COG0009	L-threonylcarbamoyladenylate synthase
FHE73_27725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FHE73_27730	COG1494	fructose-1,6-bisphosphatase
FHE73_27750	COG4821	SIS domain
FHE73_27760	COG3343	RNA polymerase activity
FHE73_27770	COG1960	acyl-CoA dehydrogenase activity
FHE73_27775	COG1960	acyl-CoA dehydrogenase activity
FHE73_27780	COG1250	3-hydroxyacyl-CoA dehydrogenase
FHE73_27785	COG0183	Belongs to the thiolase family
FHE73_27790	COG0247	lactate metabolic process
FHE73_27790	COG2181	nitrate reductase activity
FHE73_27795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHE73_27805	COG5001	Diguanylate cyclase
FHE73_27805	COG3300	MHYT domain
FHE73_27820	COG3227	Zinc metalloprotease (Elastase)
FHE73_27825	COG2197	response regulator
FHE73_27830	COG4585	Histidine kinase
FHE73_27835	COG0842	Transport permease protein
FHE73_27840	COG1131	(ABC) transporter
FHE73_27845	COG0024	Methionine aminopeptidase
FHE73_27855	COG2234	aminopeptidase activity
FHE73_27875	COG1595	DNA-templated transcription, initiation
FHE73_27885	COG4506	Protein conserved in bacteria
FHE73_27890	COG1619	proteins homologs of microcin C7 resistance protein MccF
FHE73_27910	COG0010	Belongs to the arginase family
FHE73_27915	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FHE73_27920	COG2814	Major facilitator Superfamily
FHE73_27925	COG0789	Transcriptional regulator
FHE73_27930	COG0584	glycerophosphoryl diester phosphodiesterase
FHE73_27935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHE73_27945	COG1994	Peptidase M50
FHE73_27955	COG1078	dGTPase activity
FHE73_27960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_27965	COG1120	ATPase activity
FHE73_27970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_27975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FHE73_27995	COG0280	phosphate acetyltransferase
FHE73_28010	COG3773	Cell wall hydrolase
FHE73_28020	COG2363	Small membrane protein
FHE73_28030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FHE73_28035	COG2233	PERMEase
FHE73_28040	COG0561	phosphatase activity
FHE73_28045	COG2814	Major facilitator Superfamily
FHE73_28055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FHE73_28060	COG1131	(ABC) transporter
FHE73_28065	COG2755	lipolytic protein G-D-S-L family
FHE73_28070	COG1609	Transcriptional regulator
FHE73_28080	COG0460	homoserine dehydrogenase
FHE73_28095	COG1011	Hydrolase
FHE73_28100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHE73_28110	COG2197	response regulator
FHE73_28115	COG4585	Histidine kinase
FHE73_28115	COG2203	Gaf domain
FHE73_28120	COG0351	phosphomethylpyrimidine kinase
FHE73_28125	COG3706	GGDEF domain
FHE73_28130	COG2879	small protein
FHE73_28135	COG1966	Carbon starvation protein
FHE73_28140	COG3279	Response regulator of the LytR AlgR family
FHE73_28145	COG0477	Major facilitator Superfamily
FHE73_28160	COG0438	transferase activity, transferring glycosyl groups
FHE73_28175	COG0840	transmembrane signaling receptor activity
FHE73_28185	COG1607	acyl-coa hydrolase
FHE73_28190	COG1216	Glycosyl transferase, family 2
FHE73_28205	COG1216	Glycosyl transferase, family 2
FHE73_28215	COG4485	Bacterial membrane protein, YfhO
FHE73_28220	COG0463	Glycosyl transferase, family 2
FHE73_28225	COG0488	(ABC) transporter
FHE73_28230	COG1309	transcriptional regulator
FHE73_28235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FHE73_28240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHE73_28240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHE73_28245	COG0628	permease
FHE73_28265	COG3275	phosphorelay sensor kinase activity
FHE73_28270	COG2814	Major facilitator Superfamily
FHE73_28275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FHE73_28280	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FHE73_28310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FHE73_28315	COG1272	protein, Hemolysin III
FHE73_28350	COG5002	protein histidine kinase activity
FHE73_28365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHE73_28370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FHE73_28375	COG4853	Protein conserved in bacteria
FHE73_28385	COG5002	protein histidine kinase activity
FHE73_28390	COG0745	RESPONSE REGULATOR receiver
FHE73_28420	COG0305	Participates in initiation and elongation during chromosome replication
FHE73_28430	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FHE73_28435	COG4241	membrane
FHE73_28455	COG0012	GTP binding
FHE73_28460	COG4481	Protein conserved in bacteria
FHE73_28465	COG0668	transmembrane transport
FHE73_28475	COG1475	DNA binding
FHE73_28480	COG1192	Involved in chromosome partitioning
FHE73_28505	COG1847	R3H domain protein
FHE73_28510	COG0706	membrane insertase activity
FHE73_28540	COG3647	Membrane
FHE73_28545	COG0671	phosphoesterase, PA-phosphatase related
FHE73_28560	COG2323	membrane
FHE73_28590	COG3800	Transcriptional regulator
FHE73_28590	COG1396	sequence-specific DNA binding
FHE73_28640	COG0457	Tetratricopeptide repeat
FHE73_28685	COG0776	regulation of translation
FHE73_28705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FHE73_28765	COG1404	Belongs to the peptidase S8 family
FHE73_28775	COG4585	Histidine kinase
FHE73_28780	COG0367	asparagine synthase
FHE73_28785	COG1309	transcriptional regulator
FHE73_28845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHE73_28850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FHE73_28855	COG1687	branched-chain amino acid
FHE73_28875	COG0741	lytic transglycosylase activity
FHE73_28875	COG1196	nuclear chromosome segregation
FHE73_28875	COG0739	heme binding
FHE73_28890	COG0457	Tetratricopeptide repeat
FHE73_29225	COG0583	DNA-binding transcription factor activity
FHE73_29230	COG2814	Major facilitator Superfamily
FHE73_29310	COG2311	Membrane
FHE73_29385	COG2304	oxidoreductase activity
FHE73_29405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHE73_29425	COG0776	regulation of translation
FHE73_29440	COG2002	toxin-antitoxin pair type II binding
FHE73_29450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FHE73_29540	COG0840	transmembrane signaling receptor activity
FHE73_29550	COG0657	acetylesterase activity
FHE73_29560	COG2207	Transcriptional regulator
FHE73_29625	COG0534	Mate efflux family protein
FHE73_29635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHE73_29640	COG4974	Belongs to the 'phage' integrase family
FHE73_29645	COG1876	peptidase activity
FHE73_29705	COG5658	integral membrane protein
FHE73_29760	COG3397	chitin binding
FHE73_29845	COG2274	protein secretion by the type I secretion system
FHE73_29850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FHE73_29860	COG1131	(ABC) transporter
FHE73_29875	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHE73_29925	COG3409	Peptidoglycan-binding domain 1 protein
FHE73_29925	COG5632	N-Acetylmuramoyl-L-alanine amidase
FHE73_29965	COG1131	(ABC) transporter
FHE73_29970	COG1132	(ABC) transporter
FHE73_29990	COG1475	DNA binding
FHE73_30010	COG0738	Major facilitator superfamily
FHE73_30015	COG0673	inositol 2-dehydrogenase activity
FHE73_30020	COG0561	phosphatase activity
FHE73_30030	COG1609	Transcriptional regulator
FHE73_30065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FHE73_30085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHE73_30090	COG1250	3-hydroxyacyl-CoA dehydrogenase
FHE73_30105	COG1960	acyl-CoA dehydrogenase activity
FHE73_30115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FHE73_30125	COG0300	oxidoreductase activity
FHE73_30125	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_30125	COG3321	synthase
FHE73_30125	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_30125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FHE73_30125	COG0318	PFAM AMP-dependent synthetase and ligase
FHE73_30125	COG0300	oxidoreductase activity
FHE73_30125	COG3321	synthase
FHE73_30125	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_30125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FHE73_30135	COG1923	regulation of RNA biosynthetic process
FHE73_30150	COG1309	transcriptional regulator
FHE73_30165	COG0463	Glycosyl transferase, family 2
FHE73_30185	COG1819	glycosyl
FHE73_30205	COG0584	glycerophosphoryl diester phosphodiesterase
FHE73_30255	COG0667	Aldo Keto reductase
FHE73_30285	COG4641	Protein conserved in bacteria
FHE73_30290	COG2089	acid synthase
FHE73_30305	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FHE73_30310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FHE73_30315	COG1088	dTDP-glucose 4,6-dehydratase activity
FHE73_30330	COG0463	Glycosyl transferase, family 2
FHE73_30335	COG0463	Glycosyl transferase, family 2
FHE73_30340	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_30350	COG2089	acid synthase
FHE73_30355	COG1028	Short-chain dehydrogenase reductase Sdr
FHE73_30365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FHE73_30375	COG3391	amine dehydrogenase activity
FHE73_30395	COG1396	sequence-specific DNA binding
FHE73_30420	COG0584	glycerophosphoryl diester phosphodiesterase
FHE73_30435	COG1216	Glycosyl transferase, family 2
FHE73_30440	COG1024	Enoyl-CoA hydratase
FHE73_30565	COG0582	viral genome integration into host DNA
FHE73_30585	COG0322	excinuclease ABC activity
FHE73_30680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FHE73_30685	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FHE73_30685	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FHE73_30690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FHE73_30700	COG2176	DNA-directed DNA polymerase activity