locus-tag class description F9800_00045 ENOG4108EKI Dehydrogenase F9800_00065 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase F9800_00080 ENOG4105CNW domain protein F9800_00085 ENOG4108IFG nitrite reductase, (NAD(P)H) F9800_00090 ENOG4105VCQ rubredoxin F9800_00100 ENOG4105DS0 Transcriptional regulator, Crp Fnr family F9800_00110 ENOG4105D7V transposase F9800_00125 ENOG4108QTI )-transporter F9800_00130 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) F9800_00140 ENOG4107R7I amino acid F9800_00150 ENOG4105C7B Threonine dehydratase F9800_00155 ENOG4105CUB amino acid F9800_00160 ENOG4105F2M alpha beta hydrolase fold-3 domain protein F9800_00210 ENOG4105EA8 2-Nitropropane dioxygenase F9800_00220 ENOG4105BZU Histidine kinase F9800_00225 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_00230 ENOG4105C0H protease F9800_00235 ENOG4107WD8 ABC transporter, permease F9800_00255 ENOG4105NA0 Transcriptional regulator F9800_00265 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C F9800_00290 ENOG4108NNZ chitinase F9800_00300 ENOG4105D7V transposase F9800_00315 ENOG4105CMT Dihydroxyacetone kinase F9800_00325 ENOG4105KRI phosphocarrier protein (HPr F9800_00330 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) F9800_00340 ENOG4105ETZ PTS System F9800_00345 ENOG4105F3R pts system mannose fructose sorbose family iid F9800_00355 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase F9800_00360 ENOG41061CK Antibiotic biosynthesis monooxygenase F9800_00375 ENOG4105NA0 Transcriptional regulator F9800_00385 ENOG4105PNM synthesis protein F9800_00390 ENOG4108VXD carboxy-peptidase F9800_00400 ENOG4108IMY Transcriptional regulator F9800_00405 ENOG4105BZC d-serine deaminase F9800_00435 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) F9800_00450 ENOG4105D7V transposase F9800_00455 ENOG4105KIR Thiol-disulfide oxidoreductase dcc F9800_00495 ENOG4105VZ8 Transcriptional regulator F9800_00500 ENOG4107D63 F9800_00510 ENOG4105CHH sulfate transporter F9800_00535 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase F9800_00590 ENOG4105BZ4 penicillin-binding protein F9800_00600 ENOG4108QXE glycerophosphoryl diester phosphodiesterase F9800_00615 ENOG4105DM4 PTS System F9800_00620 ENOG4105DG6 mannose-6-phosphate isomerase F9800_00625 ENOG4105BZU Histidine kinase F9800_00630 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_00640 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) F9800_00655 ENOG4108IQI permease F9800_00660 ENOG4108J5H Homocysteine s-methyltransferase F9800_00675 ENOG4108IMY Transcriptional regulator F9800_00680 ENOG4105BZC d-serine deaminase F9800_00690 ENOG4105DQ6 Transposase F9800_00710 ENOG4107SET aldo keto reductase F9800_00790 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) F9800_00800 ENOG4105CJW magnesium transporter F9800_00805 ENOG4105CNI cell division protein FtsW F9800_00810 ENOG4105FQP Beta-lactamase F9800_00835 ENOG4106A3M Cytochrome p-450 F9800_00840 ENOG410625E F9800_00880 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase F9800_00890 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase F9800_00895 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) F9800_00900 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) F9800_00905 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) F9800_00920 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) F9800_00930 ENOG4105CHR reductase F9800_00935 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase F9800_00945 ENOG4108KYE ABC-2 type transporter F9800_00950 ENOG4105CJ1 ABC, transporter F9800_00955 ENOG4105CTC Lipopolysaccharide biosynthesis protein-like protein F9800_01050 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) F9800_01065 ENOG4105BZ1 (ABC) transporter F9800_01080 ENOG4105CAQ asparagine synthetase F9800_01085 ENOG4105CHR reductase F9800_01100 ENOG41082UD thioesterase Superfamily protein F9800_01105 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) F9800_01110 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) F9800_01120 ENOG4105CEY Amp-dependent synthetase and ligase F9800_01125 ENOG4105CEY Amp-dependent synthetase and ligase F9800_01230 ENOG4107WD8 ABC transporter, permease F9800_01235 ENOG4105E98 transcriptional regulator DeoR family F9800_01240 ENOG4107XGZ Hydrolase F9800_01250 ENOG4107RF6 penicillin-binding protein F9800_01260 ENOG4105EMN RNA polymerase sigma factor F9800_01345 ENOG4108VJ1 Transcriptional regulator (CarD family F9800_01375 ENOG4107ZBN O-methyltransferase F9800_01380 ENOG4105F27 Major Facilitator F9800_01385 ENOG4105M4P Tetr family transcriptional regulator F9800_01420 ENOG4105CZV ABC transporter F9800_01425 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family F9800_01440 ENOG4105TRI Hydrolase F9800_01470 ENOG4105E98 transcriptional regulator DeoR family F9800_01590 ENOG4105EKQ RNA-directed DNA polymerase F9800_01595 ENOG41065S2 pneumococcal vaccine antigen F9800_01850 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) F9800_01855 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) F9800_01925 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) F9800_02130 ENOG4108VXD carboxy-peptidase F9800_02270 ENOG4105IEH endo-beta-N-acetylglucosaminidase F9800_02345 ENOG4105MZU cell filamentation protein F9800_02395 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase F9800_02400 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase F9800_02520 ENOG4105C2M dna polymerase I F9800_02550 ENOG410906U SprT-like F9800_02630 ENOG4105EQI Metal Dependent Phosphohydrolase F9800_02705 ENOG4105D9P serine threonine protein kinase F9800_03115 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) F9800_03220 ENOG4105C4R Atp-dependent dna helicase F9800_03485 ENOG4105C2M dna polymerase I F9800_03775 ENOG4107XK4 dna polymerase iii subunits gamma and tau F9800_04295 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate F9800_04330 ENOG4105K4W Could be involved in septation (By similarity) F9800_04355 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) F9800_04425 ENOG4105C0B DNA polymerase III (alpha subunit) F9800_04435 ENOG4105C0B DNA polymerase III (alpha subunit) F9800_04450 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) F9800_04460 ENOG4105EKQ RNA-directed DNA polymerase F9800_04470 ENOG4105GJD protein, conserved in bacteria F9800_04510 ENOG4107JM4 Tetratricopeptide repeat F9800_04565 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase F9800_04680 ENOG4108UUM single-stranded DNA-binding protein F9800_04690 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) F9800_04720 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) F9800_04725 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) F9800_04745 ENOG4105C4R Atp-dependent dna helicase F9800_04750 ENOG4107Z0P This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) F9800_04755 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) F9800_04795 ENOG4105K6T rare lipoprotein A F9800_04800 ENOG4105C0D helicase F9800_04815 ENOG4105BZU Histidine kinase F9800_04820 ENOG4105GR3 Histidine kinase F9800_04840 ENOG4105ZMH deoxynucleoside kinase F9800_05025 ENOG4105C5T Phosphoribosyl pyrophosphate synthase F9800_05035 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) F9800_05050 ENOG4106FN3 tellurium resistance protein F9800_05055 ENOG4106FN3 tellurium resistance protein F9800_05065 ENOG4107TS3 membrane protein, TerC F9800_05075 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) F9800_05085 ENOG4105D9N nucleoside F9800_05110 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) F9800_05115 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) F9800_05120 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) F9800_05125 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) F9800_05160 ENOG4108IBT Inherit from COG: transposase F9800_05290 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase F9800_05465 ENOG4105E1K spore germination protein F9800_05490 ENOG4105K70 DNA-binding protein F9800_05495 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) F9800_05500 ENOG4105KRN Transcriptional regulator, abrb family F9800_05515 ENOG4105C87 Aminotransferase class I and II F9800_05520 ENOG410880H cysteine synthase F9800_05525 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) F9800_05655 ENOG4107RBB ABC transporter, permease F9800_05660 ENOG4105C19 ABC transporter F9800_05685 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) F9800_05715 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) F9800_05720 ENOG4105KRN Transcriptional regulator, abrb family F9800_05785 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj F9800_05845 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) F9800_05910 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) F9800_05915 ENOG410848D S4 domain protein YaaA F9800_05930 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) F9800_05955 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) F9800_05990 ENOG4105ZMH deoxynucleoside kinase F9800_06000 ENOG4105GTG Isochorismatase F9800_06010 ENOG4108Z6B deaminase F9800_06020 ENOG4105C6E dna polymerase iii F9800_06040 ENOG41067KS pro-sigma K processing F9800_06065 ENOG4105CXN decarboxylase F9800_06075 ENOG4105FA2 dna polymerase iii F9800_06080 ENOG4105MA4 psp1 domain protein F9800_06090 ENOG41060K3 Methyltransferase F9800_06100 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) F9800_06105 ENOG4105KRN Transcriptional regulator, abrb family F9800_06110 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) F9800_06115 ENOG4105F8V Hydrolase, tatD family F9800_06120 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) F9800_06130 ENOG4105XFA sporulation peptidase YabG F9800_06135 ENOG4105W42 Veg protein F9800_06150 ENOG4105DFT pur operon repressor F9800_06155 ENOG4105KME endoribonuclease L-psp F9800_06170 ENOG4105C5T Phosphoribosyl pyrophosphate synthase F9800_06175 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) F9800_06185 ENOG4108JA2 transcriptioN-repair coupling factor F9800_06190 ENOG4108M14 stage v sporulation protein t F9800_06200 ENOG4108IY2 MazG family F9800_06205 ENOG41082I2 s4 domain protein F9800_06210 ENOG4105VYY sporulation protein yabp F9800_06225 ENOG41060GV RNA binding s1 domain protein F9800_06245 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) F9800_06250 ENOG4108UGV hypoxanthine phosphoribosyltransferase F9800_06255 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) F9800_06270 ENOG4105C6T cysteine synthase F9800_06275 ENOG4105CRQ synthase (Component I) F9800_06280 ENOG4105DDQ anthranilate synthase F9800_06285 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 F9800_06290 ENOG4105EEI dihydropteroate synthase F9800_06295 ENOG4105KRF dihydroneopterin aldolase F9800_06300 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase F9800_06310 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) F9800_06340 ENOG4108Z0C Uvrb UvrC protein F9800_06355 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) F9800_06365 ENOG4105CTP PilT protein domain protein F9800_06385 ENOG4105D7W serine acetyltransferase F9800_06400 ENOG4105C2N RNA methyltransferase TrmH family group 3 F9800_06405 ENOG4105M0M Tetracycline resistance protein F9800_06410 ENOG4105QIV RNA polymerase F9800_06425 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) F9800_06450 ENOG4107Y49 methyltransferase F9800_06460 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) F9800_06465 ENOG4105XPM ribosomal protein F9800_06575 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) F9800_06600 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) F9800_06610 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) F9800_06620 ENOG41067V7 50S ribosomal protein L36 F9800_06645 ENOG4108JJB ABC transporter F9800_06650 ENOG4108JJB ABC transporter F9800_06655 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) F9800_06660 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) F9800_06685 ENOG4105D1F ATP-binding protein F9800_06700 ENOG4108NMV polysaccharide deacetylase F9800_06780 ENOG4105C8B TIGR00159 family F9800_06785 ENOG4107U5W ybbr family F9800_06800 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) F9800_06820 ENOG4108PSK reductase F9800_06825 ENOG4108UMI ABC transporter, permease F9800_06830 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) F9800_06835 ENOG4105D01 (LipO)protein F9800_06840 ENOG4105CB2 alcohol dehydrogenase F9800_06850 ENOG4105IQ5 FAD linked oxidase domain protein F9800_06865 ENOG4105C2C drug resistance transporter, Bcr CflA F9800_06885 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component F9800_06890 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component F9800_06895 ENOG4105C3U ABC transporter F9800_06900 ENOG4108JQ7 (ABC) transporter F9800_06920 ENOG4108J59 Extracellular solute-binding protein, family 5 F9800_06945 ENOG4105E0C molybdate abc transporter F9800_06950 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein F9800_06955 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family F9800_06985 ENOG4105F6E Acyl-transferase F9800_07005 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) F9800_07020 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) F9800_07040 ENOG4105C5H ABC transporter F9800_07055 ENOG4105DEF Extracellular solute-binding protein, family 5 F9800_07065 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component F9800_07070 ENOG4105C3U ABC transporter F9800_07075 ENOG4108JQ7 (ABC) transporter F9800_07080 ENOG410667J hydrolase F9800_07105 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase F9800_07110 ENOG4105ERH Fumarylacetoacetate hydrolase F9800_07120 ENOG4105CUB amino acid F9800_07125 ENOG4108SC4 )-transporter F9800_07130 ENOG4105CPF Cell wall formation (By similarity) F9800_07135 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) F9800_07160 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein F9800_07165 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) F9800_07175 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) F9800_07280 ENOG4105K8N protein family UPF0079, ATPase F9800_07285 ENOG41072GX Peptidase M22 Glycoprotease F9800_07290 ENOG410801F ribosomal-protein-alanine acetyltransferase F9800_07295 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) F9800_07300 ENOG4105C5H ABC transporter F9800_07315 ENOG4108TYN CAAX amino terminal protease family protein F9800_07395 ENOG4108IBT Inherit from COG: transposase F9800_07435 ENOG4106BHR ftsk SpoIIIE family protein F9800_07445 ENOG4106128 DNA-binding helix-turn-helix protein F9800_07460 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) F9800_07470 ENOG4105C7N Xanthine uracil vitamin C permease F9800_07480 ENOG4105BZU Histidine kinase F9800_07510 ENOG4107ZXU DSBA oxidoreductase F9800_07530 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family F9800_07555 ENOG410631K Membrane F9800_07605 ENOG4105DPZ Two component transcriptional regulator (Winged helix family F9800_07625 ENOG410631K Membrane F9800_07650 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) F9800_07655 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit F9800_07660 ENOG4105C83 adenylosuccinate lyase F9800_07670 ENOG4105VR9 phosphoribosylformylglycinamidine synthase F9800_07695 ENOG4108V3E phosphoribosylglycinamide formyltransferase F9800_07705 ENOG4105C12 Phosphoribosylglycinamide synthetase F9800_07730 ENOG4105C4R Atp-dependent dna helicase F9800_07755 ENOG4108W2Y isochorismatase F9800_07765 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) F9800_07770 ENOG4108UMI ABC transporter, permease F9800_07775 ENOG4105D01 (LipO)protein F9800_07795 ENOG410834F Transcriptional regulator F9800_07800 ENOG4107I77 yiaA/B two helix domain F9800_07820 ENOG4105CBD Diacylglycerol kinase F9800_07830 ENOG4108JPW Aminotransferase F9800_07840 ENOG4105C26 Dehydrogenase F9800_07845 ENOG4105KPY Small multidrug resistance protein F9800_07870 ENOG4105D9N nucleoside F9800_07875 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) F9800_07885 ENOG4108W15 Protein of unknown function (DUF1456) F9800_07905 ENOG4105DTQ mandelate racemase muconate lactonizing F9800_07915 ENOG4105DFD Na H antiporter F9800_07935 ENOG4105D3R alkyl hydroperoxide reductase F9800_07940 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) F9800_07945 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) F9800_07950 ENOG4107W7X Aldolase F9800_07960 ENOG4105EHG Permease protein F9800_07965 ENOG4105DQ5 transport system permease protein F9800_07970 ENOG4108V5C ABC transporter F9800_08000 ENOG4106UIA F9800_08005 ENOG4106UIA F9800_08020 ENOG4105BZU Histidine kinase F9800_08040 ENOG410756H nucleotidyltransferase F9800_08045 ENOG4105D2S major facilitator superfamily F9800_08060 ENOG4105E5Q amino acid AbC transporter F9800_08065 ENOG4105EAB amino acid AbC transporter F9800_08070 ENOG4105CDA abc transporter atp-binding protein F9800_08075 ENOG4105C8Q Methyl-accepting chemotaxis F9800_08090 ENOG4105DBV ornithine carbamoyltransferase F9800_08100 ENOG4105C5B carbamate kinase F9800_08105 ENOG4108W63 CRP FNR family transcriptional regulator F9800_08115 ENOG4105DNP FAD linked oxidase domain protein F9800_08125 ENOG4105CI1 PTS System F9800_08140 ENOG4105C9U ATP-dependent DNA helicase RecQ F9800_08155 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter F9800_08175 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component F9800_08180 ENOG4105D2X ABC transporter substrate-binding protein F9800_08190 ENOG4105C5H ABC transporter F9800_08225 ENOG41062JF Transcriptional regulator F9800_08240 ENOG4105DEU major facilitator superfamily F9800_08270 ENOG4108N0M stress protein F9800_08275 ENOG4106FN3 tellurium resistance protein F9800_08280 ENOG4106FN3 tellurium resistance protein F9800_08285 ENOG4107TS3 membrane protein, TerC F9800_08290 ENOG4108TTB tellurium resistance protein F9800_08305 ENOG41068PA UPF0435 protein F9800_08310 ENOG4105KJF protein tyrosine phosphatase F9800_08320 ENOG4107U9T Pfam:Ribonuclease_BN F9800_08325 ENOG4105C59 p-type ATPase F9800_08330 ENOG4108IPJ Membrane F9800_08350 ENOG4107ZTW SNARE associated Golgi F9800_08365 ENOG410606W general stress protein F9800_08370 ENOG4105UPD Calcium Proton F9800_08405 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) F9800_08420 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) F9800_08430 ENOG4108JUB Transcriptional regulator F9800_08440 ENOG4108IQI permease F9800_08465 ENOG4105CSV Glutaminase F9800_08485 ENOG4108A04 Beta-lactamase F9800_08500 ENOG4105CKK Glycosyl transferase, family 2 F9800_08505 ENOG4107QQG Dehydrogenase F9800_08510 ENOG4105C3I Nad-dependent epimerase dehydratase F9800_08515 ENOG4105CKK Glycosyl transferase, family 2 F9800_08530 ENOG4105F1A Pyruvate formate-lyase F9800_08550 ENOG4105CI2 imidazolone-5-propionate hydrolase F9800_08555 ENOG4105ECP epimerase F9800_08585 ENOG41067AE Membrane-bound metal-dependent hydrolase F9800_08590 ENOG4105CEN a g-specific adenine glycosylase F9800_08595 ENOG4106BXE F9800_08615 ENOG4105BZ1 (ABC) transporter F9800_08620 ENOG4107NBY Membrane F9800_08625 ENOG4105CBC glutamate synthase F9800_08635 ENOG4108IUW ABC transporter F9800_08655 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen F9800_08660 ENOG4105G5W regulator Fur family F9800_08790 ENOG4108JQC penicillin-binding protein 1A F9800_08795 ENOG4108R9S DSBA oxidoreductase F9800_08805 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) F9800_08815 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) F9800_08820 ENOG4105BZU Histidine kinase F9800_08825 ENOG4105CYN Serine protein kinase F9800_08840 ENOG4105C94 Transporter F9800_08855 ENOG4105DZ6 Band 7 protein F9800_08865 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism F9800_08870 ENOG4108V9W transcriptional regulatory protein F9800_08875 ENOG4105D4T Citrate transporter F9800_08900 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator F9800_08905 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) F9800_08910 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component F9800_08915 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component F9800_08920 ENOG4105BZ7 extracellular solute-binding protein family 1 F9800_08925 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) F9800_08930 ENOG4108STX response regulator F9800_08935 ENOG4105US7 Histidine kinase F9800_08960 ENOG4108MRH transcriptional regulatory protein F9800_08970 ENOG4105C6K Malic enzyme F9800_08980 ENOG4108UZ3 Transporter F9800_08985 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family F9800_08990 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family F9800_09000 ENOG4105BZU Histidine kinase F9800_09025 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) F9800_09030 ENOG4108JB9 formate dehydrogenase F9800_09050 ENOG4105CUB amino acid F9800_09060 ENOG4105C59 p-type ATPase F9800_09065 ENOG4105DAP Nicotinate phosphoribosyltransferase F9800_09100 ENOG41073R8 VanW family F9800_09105 ENOG4108KGH TRANSCRIPTIONal F9800_09110 ENOG4105D9N nucleoside F9800_09115 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase F9800_09120 ENOG4105C37 (CBS) domain F9800_09125 ENOG4108IJ0 Aspartate ammonia-lyase F9800_09130 ENOG4105DAA L-lactate F9800_09145 ENOG4105DUX Transporter F9800_09150 ENOG4108MES Periplasmic binding protein F9800_09155 ENOG4105DQ5 transport system permease protein F9800_09160 ENOG4108IHU transport system permease protein F9800_09165 ENOG4105E0A ABC, transporter F9800_09180 ENOG4105EXW epimerase dehydratase F9800_09190 ENOG4107T89 von Willebrand factor, type A F9800_09195 ENOG4105GMT ATPase associated with various cellular activities aaa_5 F9800_09200 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) F9800_09210 ENOG4105BZU Histidine kinase F9800_09215 ENOG4105D5Q Arginine ornithine antiporter F9800_09220 ENOG4107414 GntR family transcriptional regulator F9800_09225 ENOG4105C5Y PTS System F9800_09230 ENOG4105CG3 alpha amylase, catalytic region F9800_09245 ENOG4105E1K spore germination protein F9800_09250 ENOG4105CRN Aminoglycoside phosphotransferase F9800_09255 ENOG4105BZG amino acid carrier protein F9800_09265 ENOG4105CDA abc transporter atp-binding protein F9800_09270 ENOG4105CT1 (ABC) transporter F9800_09275 ENOG4105EAD ABC transporter F9800_09280 ENOG4105DRP amino acid AbC transporter F9800_09285 ENOG4108IQI permease F9800_09300 ENOG4105GFR rna polymerase sigma factor F9800_09310 ENOG4105D29 Helix-turn-helix type 11 domain protein F9800_09315 ENOG4105NAE bifunctional deaminase-reductase domain protein F9800_09320 ENOG4105BZU Histidine kinase F9800_09345 ENOG4105CHH sulfate transporter F9800_09350 ENOG41068KF Universal stress protein F9800_09360 ENOG4105CXY transporter F9800_09365 ENOG41067TZ transcriptional regulator, MarR family F9800_09370 ENOG4105C0R drug resistance transporter emrb qaca subfamily F9800_09375 ENOG4105ETE Transcriptional regulator (LacI family F9800_09380 ENOG4108RVA ribokinase F9800_09390 ENOG4105C2J ABC transporter F9800_09395 ENOG4105CNN ABC, transporter F9800_09400 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator F9800_09405 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) F9800_09445 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) F9800_09475 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) F9800_09480 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer F9800_09485 ENOG41069ER domain protein F9800_09490 ENOG4105VZ8 Transcriptional regulator F9800_09495 ENOG4107D63 F9800_09510 ENOG4105DUX Transporter F9800_09530 ENOG4105C85 amino acid F9800_09535 ENOG4105C7N Xanthine uracil vitamin C permease F9800_09550 ENOG4105MA6 gCN5-related N-acetyltransferase F9800_09575 ENOG4105BZ9 Cytochrome C oxidase, subunit I F9800_09580 ENOG4105E2S oxidase) subunit II F9800_09600 ENOG4106CAD Protein of unknown function (DUF3311) F9800_09605 ENOG4105E1V na solute symporter F9800_09620 ENOG4108NHD germination protein F9800_09625 ENOG4105CE1 Ferrous iron transport protein b F9800_09630 ENOG4105CE1 Ferrous iron transport protein b F9800_09635 ENOG4105CE1 Ferrous iron transport protein b F9800_09640 ENOG4105CVA phosphate F9800_09645 ENOG4105C8U phosphate abc transporter F9800_09650 ENOG4105E2Z phosphate ABC transporter (Permease F9800_09790 ENOG41080XQ Signal transduction protein with cbs domains F9800_09810 ENOG4105ETU transcriptional activator (TenA F9800_09820 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component F9800_09830 ENOG4108VEU Thiamine monophosphate synthase F9800_09835 ENOG41080HI glycine oxidase F9800_09850 ENOG4105D06 uba thif-type nad fad binding protein F9800_09855 ENOG4105DWF phosphomethylpyrimidine kinase F9800_09905 ENOG4108INS Transcriptional regulator F9800_09920 ENOG4105C7N Xanthine uracil vitamin C permease F9800_09930 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein F9800_09945 ENOG4105K63 Thioredoxin F9800_09965 ENOG4108B31 Spore germination protein F9800_09985 ENOG4107Y03 Nitroreductase F9800_09990 ENOG4105ED1 spovr family F9800_10010 ENOG4105XTG Pfam:DUF156 F9800_10015 ENOG4105VFE sira family F9800_10020 ENOG4107TPS domain protein F9800_10025 ENOG4105VFE sira family F9800_10030 ENOG4105VFE sira family F9800_10040 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase F9800_10045 ENOG41087NI Sulfite exporter TauE/SafE F9800_10055 ENOG4108KGH TRANSCRIPTIONal F9800_10085 ENOG4105EMD TRANSCRIPTIONal F9800_10090 ENOG4105VCP PTS System F9800_10095 ENOG4105VZJ PTS System F9800_10120 ENOG41069ER domain protein F9800_10125 ENOG4107RBB ABC transporter, permease F9800_10130 ENOG4105C19 ABC transporter F9800_10160 ENOG4105WEF catalase F9800_10195 ENOG4107T5V SNARE associated Golgi F9800_10225 ENOG4105CUB amino acid F9800_10230 ENOG4107RWR Sodium hydrogen exchanger F9800_10240 ENOG4106KNT transcriptional regulator F9800_10280 ENOG4108YXU transcriptional regulator AsnC family F9800_10290 ENOG4105UBK short-chain dehydrogenase reductase F9800_10295 ENOG4105W1Y Transcriptional regulator F9800_10300 ENOG4105KPY Small multidrug resistance protein F9800_10340 ENOG4107RKG DJ-1/PfpI family F9800_10345 ENOG4105CH6 catalase F9800_10355 ENOG4105D5Q Arginine ornithine antiporter F9800_10360 ENOG4105C26 Dehydrogenase F9800_10370 ENOG4105BZ1 (ABC) transporter F9800_10375 ENOG4105BZ1 (ABC) transporter F9800_10390 ENOG4105DRP amino acid AbC transporter F9800_10395 ENOG4105CDA abc transporter atp-binding protein F9800_10410 ENOG410839P F9800_10445 ENOG4107FQX Alpha-acetolactate decarboxylase F9800_10465 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein F9800_10470 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase F9800_10475 ENOG4105D4P Coproporphyrinogen iii oxidase F9800_10480 ENOG4105CEY Amp-dependent synthetase and ligase F9800_10490 ENOG4105CHH sulfate transporter F9800_10515 ENOG4105CGU Enoyl-CoA hydratase F9800_10535 ENOG4105DER m42 family F9800_10560 ENOG4105CIF Ornithine Cyclodeaminase F9800_10575 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component F9800_10585 ENOG4108JQ7 (ABC) transporter F9800_10615 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase F9800_10630 ENOG4105D06 uba thif-type nad fad binding protein F9800_10635 ENOG4107SFI Major Facilitator superfamily F9800_10695 ENOG4105GMB type VI secretion system effector, hcp1 family F9800_10750 ENOG4105CSH Transporter F9800_10760 ENOG4108MRH transcriptional regulatory protein F9800_10805 ENOG4105C4R Atp-dependent dna helicase F9800_10825 ENOG4105CDU Replicative dna helicase F9800_10855 ENOG4105C0R drug resistance transporter emrb qaca subfamily F9800_10935 ENOG4105F6J Alpha beta hydrolase fold F9800_11000 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase F9800_11010 ENOG4105F27 Major Facilitator F9800_11015 ENOG4105WAB arsR family transcriptional regulator F9800_11030 ENOG4105CMT Dihydroxyacetone kinase F9800_11045 ENOG4105CMT Dihydroxyacetone kinase F9800_11170 ENOG4105WN5 stage II sporulation protein F9800_11180 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_11190 ENOG4108MJI response regulator F9800_11195 ENOG4105BZU Histidine kinase F9800_11200 ENOG4105BZU Histidine kinase F9800_11230 ENOG4105D7V transposase F9800_11240 ENOG4107QHE Choloylglycine hydrolase F9800_11260 ENOG4107VRP DNA repair exonuclease F9800_11265 ENOG4106D4I domain protein F9800_11280 ENOG410829K Lysine exporter protein (Lyse ygga) F9800_11305 ENOG4108MUZ hydrolase F9800_11330 ENOG4105F0F Oxalate decarboxylase F9800_11335 ENOG41067QW Transcriptional regulator F9800_11340 ENOG4105D7V transposase F9800_11345 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator F9800_11360 ENOG4105C6V Glycerol-3-phosphate dehydrogenase F9800_11390 ENOG4105EEM helicase F9800_11395 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) F9800_11425 ENOG4105K59 histidine triad (HIT) protein F9800_11455 ENOG410905X membrane-flanked domain protein F9800_11460 ENOG4105CKV Membrane F9800_11500 ENOG410905X membrane-flanked domain protein F9800_11510 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation F9800_11515 ENOG4105BZ4 penicillin-binding protein F9800_11525 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) F9800_11530 ENOG4105C1Q protoporphyrinogen oxidase F9800_11560 ENOG4105ECB domain protein F9800_11590 ENOG4106AXD F9800_11595 ENOG4108RQ5 Beta-lactamase domain-containing protein F9800_11600 ENOG4105DF9 Lipoate-protein, ligase F9800_11610 ENOG4105CEY Amp-dependent synthetase and ligase F9800_11660 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) F9800_11670 ENOG4105ENX hydrolase F9800_11675 ENOG4107RN3 metallophosphoesterase F9800_11680 ENOG4107TVP HD domain protein F9800_11690 ENOG4108AEY RNA polymerase sigma factor F9800_11700 ENOG41086D8 Transcriptional regulator F9800_11720 ENOG4105DPZ Two component transcriptional regulator (Winged helix family F9800_11740 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 F9800_11745 ENOG4105C8Q Methyl-accepting chemotaxis F9800_11755 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) F9800_11765 ENOG4107QP3 malate synthase g F9800_11785 ENOG4105VEQ Cold shock protein F9800_11800 ENOG4105XVF Competence transcription factor F9800_11865 ENOG4105ERH Fumarylacetoacetate hydrolase F9800_11875 ENOG4105C8Y Acetylornithine aminotransferase F9800_11895 ENOG4105CAQ asparagine synthetase F9800_11900 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) F9800_11905 ENOG4105CH6 catalase F9800_11910 ENOG4105BZU Histidine kinase F9800_11935 ENOG4105QNR S1 RNA binding domain protein F9800_11940 ENOG4105CNA YD repeat protein F9800_11990 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) F9800_12000 ENOG4107AYK membrAne F9800_12005 ENOG41073B9 F9800_12015 ENOG4108KP7 hydrolase F9800_12025 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit F9800_12050 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) F9800_12055 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) F9800_12075 ENOG4105C31 Tryptophanyl-tRNA synthetase F9800_12095 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component F9800_12100 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component F9800_12110 ENOG4108JQ7 (ABC) transporter F9800_12115 ENOG4105UQX Mate efflux family protein F9800_12145 ENOG4108ZCF integral membrane protein F9800_12155 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) F9800_12165 ENOG4105DPN Oligoendopeptidase f F9800_12175 ENOG4108Z18 K06886 hemoglobin F9800_12180 ENOG4105MIX Adenylate cyclase F9800_12195 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) F9800_12200 ENOG4105EMS pseudouridine synthase F9800_12220 ENOG4105K64 Glycosyl transferase, family 2 F9800_12260 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) F9800_12265 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase F9800_12275 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase F9800_12350 ENOG4105CK7 Sodium proline symporter F9800_12355 ENOG4105CRQ synthase (Component I) F9800_12360 ENOG4105DDQ anthranilate synthase F9800_12455 ENOG4105C7S Dehydrogenase F9800_12465 ENOG4105VZ8 Transcriptional regulator F9800_12500 ENOG4108IUX (ABC) transporter F9800_12505 ENOG4105RHA ABC transporter, permease F9800_12530 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) F9800_12540 ENOG4105DZ1 carboxypeptidase F9800_12545 ENOG4105VFR signal peptidase F9800_12580 ENOG4105C26 Dehydrogenase F9800_12585 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) F9800_12590 ENOG4105F38 ABC transporter, permease F9800_12595 ENOG4105D38 putrescine abc transporter F9800_12600 ENOG4107RUE extracellular solute-binding protein family 1 F9800_12605 ENOG410841Q phosphoesterase PA-phosphatase related protein F9800_12610 ENOG4105EYF MMPL domain protein F9800_12620 ENOG4108YBP pseudouridine synthase F9800_12630 ENOG4105K4I Scp-like extracellular F9800_12635 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) F9800_12640 ENOG4105CQB FAD linked oxidase domain protein F9800_12655 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_12660 ENOG4105BZU Histidine kinase F9800_12665 ENOG4105JXH GntR family transcriptional regulator F9800_12685 ENOG4106A3R peptidase F9800_12695 ENOG4108QTI )-transporter F9800_12700 ENOG4107TS3 membrane protein, TerC F9800_12705 ENOG4105CZN Potassium uptake protein F9800_12710 ENOG410681C small acid-soluble spore protein F9800_12715 ENOG4108Z7G MaoC domain protein dehydratase F9800_12735 ENOG4105CHR reductase F9800_12765 ENOG4105C4Y ABC transporter F9800_12770 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) F9800_12775 ENOG4107RCV ABC transporter, permease F9800_12795 ENOG4105E98 transcriptional regulator DeoR family F9800_12805 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) F9800_12815 ENOG4105PXI polysaccharide deacetylase F9800_12825 ENOG4105BZU Histidine kinase F9800_12830 ENOG41090MY MarR family Transcriptional regulator F9800_12840 ENOG4106DF1 F9800_12845 ENOG4105BZU Histidine kinase F9800_12855 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase F9800_12860 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) F9800_12905 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) F9800_12910 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) F9800_12915 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) F9800_12920 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family F9800_12925 ENOG4105CZV ABC transporter F9800_12935 ENOG4105CJ1 ABC, transporter F9800_12975 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A F9800_12980 ENOG4105EA8 2-Nitropropane dioxygenase F9800_12985 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD F9800_12995 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein F9800_13015 ENOG4105NQC Flavodoxin F9800_13045 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) F9800_13075 ENOG4105CZN Potassium uptake protein F9800_13080 ENOG41063Y9 F9800_13085 ENOG4105KBJ sporulation protein ytfj F9800_13105 ENOG4105CM2 brancheD-chain amino acid aminotransferase F9800_13110 ENOG4105C7K acetolactate synthase F9800_13115 ENOG4108ZP8 Acetolactate synthase small subunit F9800_13120 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase F9800_13155 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) F9800_13190 ENOG4107RVV histidinol phosphate phosphatase, hisj family F9800_13205 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase F9800_13210 ENOG4105E0M Sulfatase F9800_13220 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) F9800_13240 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) F9800_13245 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) F9800_13255 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) F9800_13260 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein F9800_13265 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein F9800_13270 ENOG4105C8J )-transporter F9800_13290 ENOG4105DFD Na H antiporter F9800_13310 ENOG4105ENE Histidine kinase F9800_13315 ENOG4105WH1 Two component transcriptional regulator luxr family F9800_13335 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) F9800_13360 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) F9800_13380 ENOG4105CJ3 phosphate transporter F9800_13385 ENOG4107GRR phosphate transport regulator F9800_13390 ENOG4105BZ4 penicillin-binding protein F9800_13405 ENOG4105BZU Histidine kinase F9800_13410 ENOG4105I3N Conserved Protein F9800_13425 ENOG4105BZU Histidine kinase F9800_13455 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) F9800_13460 ENOG4105DZ1 carboxypeptidase F9800_13465 ENOG4108JIC nucleoside recognition domain protein F9800_13475 ENOG4105FE9 pseudouridine synthase F9800_13480 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen F9800_13485 ENOG4107TWT Cytochrome c biogenesis protein F9800_13490 ENOG4105CRE cytochrome C F9800_13495 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_13500 ENOG4105BZU Histidine kinase F9800_13505 ENOG4108WBT adenosyltransferase F9800_13510 ENOG41063SB peptidase F9800_13520 ENOG4108SAX Membrane F9800_13535 ENOG4105C9U ATP-dependent DNA helicase RecQ F9800_13540 ENOG4105I7S Abortive infection protein F9800_13550 ENOG4107RGJ metallophosphoesterase F9800_13555 ENOG4108XDN Transcriptional regulator F9800_13560 ENOG4108S6Z Negative regulator of genetic competence F9800_13585 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase F9800_13590 ENOG4107RB3 L-asparaginase F9800_13620 ENOG4105S2F F9800_13625 ENOG41065D1 F9800_13655 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) F9800_13670 ENOG4105XXQ heptaprenyl diphosphate synthase component I F9800_13680 ENOG4105EAH synthase F9800_13685 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) F9800_13690 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase F9800_13710 ENOG41068YB TPR repeat-containing protein F9800_13725 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) F9800_13730 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) F9800_13765 ENOG4108JYZ YitT family F9800_13770 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase F9800_13785 ENOG4105FJR Lmbe family F9800_13790 ENOG4105CPK Glycosyl transferase (Group 1 F9800_13830 ENOG4105DVT helicase F9800_13835 ENOG4105YAC F9800_13855 ENOG4105CSM endonuclease III F9800_13865 ENOG4105BZ4 penicillin-binding protein F9800_13920 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) F9800_13930 ENOG4105DVT helicase F9800_13935 ENOG4105CTD carboxy-peptidase F9800_13950 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) F9800_13965 ENOG4105C2W permease F9800_13970 ENOG4105DHF Membrane F9800_13975 ENOG410890F Dynamin family F9800_13985 ENOG4108W0I acetyltransferase F9800_13995 ENOG4105KHC sulfurtransferase F9800_14020 ENOG4106032 Glutathionylspermidine synthase F9800_14055 ENOG4105HTX biosynthesis protein F9800_14085 ENOG4105CPK Glycosyl transferase (Group 1 F9800_14100 ENOG4108SZE gCN5-related N-acetyltransferase F9800_14120 ENOG41081VK Ribonuclease F9800_14185 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) F9800_14195 ENOG4107RWR Sodium hydrogen exchanger F9800_14205 ENOG4108Z5V transcriptional regulator, merr family F9800_14215 ENOG4105H67 Protein of unknown function (DUF421) F9800_14220 ENOG41080C8 DUF218 domain F9800_14260 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) F9800_14270 ENOG4107R0U MotA TolQ exbB proton channel F9800_14275 ENOG4105ER2 Ompa motb domain protein F9800_14280 ENOG4107YTP response regulator receiver protein F9800_14285 ENOG4105CBS Chea signal transduction histidine kinase F9800_14290 ENOG4105DD5 Flagellar motor switch protein F9800_14305 ENOG4105BZU Histidine kinase F9800_14325 ENOG4105E1Q flagellar hook-associated protein F9800_14330 ENOG4105DTJ flagellar hook-associated protein F9800_14350 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) F9800_14355 ENOG4108ZC9 flagellar basal-body rod protein flgc F9800_14360 ENOG41075Z6 flagellar hook-basal body complex protein fliE F9800_14365 ENOG4107U2N Flagellar M-ring protein F9800_14370 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) F9800_14400 ENOG4105BZE flagellar hook protein, FlgE F9800_14415 ENOG4107R88 Chemotaxis protein (CheV) F9800_14445 ENOG4105I03 Flagellin F9800_14450 ENOG4105E4C Lytic transglycosylase catalytic F9800_14460 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) F9800_14465 ENOG4105DD5 Flagellar motor switch protein F9800_14475 ENOG4105CN7 Flagellar biosynthetic protein FliP F9800_14480 ENOG4105VS8 Flagellar biosynthetic protein fliq F9800_14490 ENOG4105D00 flagellar biosynthetic protein flhB F9800_14495 ENOG4105D7B Flagellar biosynthesis protein flha F9800_14500 ENOG4105FZW flagellar biosynthesis regulator FlhF F9800_14505 ENOG4105KTQ flagellar basal-body rod protein F9800_14510 ENOG4105CPU Monooxygenase F9800_14515 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) F9800_14545 ENOG4105KAC Antibiotic biosynthesis monooxygenase F9800_14550 ENOG4107QZ7 Cellulose synthase catalytic subunit F9800_14575 ENOG4105DUM transcriptional regulator, lysR family F9800_14580 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) F9800_14590 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component F9800_14595 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) F9800_14630 ENOG4105CVJ phosphoglycerate mutase F9800_14640 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) F9800_14650 ENOG4105K56 Transcriptional regulator F9800_14660 ENOG4105CAQ asparagine synthetase F9800_14680 ENOG4105PGM cation diffusion facilitator family transporter F9800_14700 ENOG4105CKI cobalamin synthesis protein F9800_14710 ENOG4108PJD permease F9800_14725 ENOG4105DFD Na H antiporter F9800_14730 ENOG4105VUF Transcriptional regulator F9800_14740 ENOG4105C9Q fumarate hydratase class II F9800_14760 ENOG4107QJQ Mate efflux family protein F9800_14765 ENOG4105EC3 peptidase S51, dipeptidase E F9800_14785 ENOG4107QIV Cytochrome c biogenesis protein F9800_14790 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen F9800_14800 ENOG4107JM4 Tetratricopeptide repeat F9800_14820 ENOG4106BRA Membrane F9800_14860 ENOG4105CJ1 ABC, transporter F9800_14880 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) F9800_14890 ENOG4108IJ0 Aspartate ammonia-lyase F9800_14895 ENOG4105C6K Malic enzyme F9800_14950 ENOG4105FVX F9800_14955 ENOG4105E09 nadh pyrophosphatase F9800_14970 ENOG4105CSR polyphosphate kinase 2 F9800_14975 ENOG4105U3E Transcriptional regulator F9800_14985 ENOG4105DXI Major Facilitator superfamily F9800_14995 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) F9800_15000 ENOG4105EU0 Major facilitator Superfamily F9800_15005 ENOG4105C6T cysteine synthase F9800_15025 ENOG4105C8J )-transporter F9800_15035 ENOG4105X5K response regulator receiver protein F9800_15040 ENOG4105H67 Protein of unknown function (DUF421) F9800_15065 ENOG4105CHR reductase F9800_15070 ENOG4105CM2 brancheD-chain amino acid aminotransferase F9800_15075 ENOG4105C7K acetolactate synthase F9800_15085 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase F9800_15095 ENOG4105C7B Threonine dehydratase F9800_15120 ENOG4105C6X Major Facilitator F9800_15125 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b F9800_15140 ENOG4105DY9 regulatoR F9800_15145 ENOG4105CYC Transferase F9800_15170 ENOG41068WN F9800_15190 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) F9800_15205 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) F9800_15210 ENOG4105C0X amino acid F9800_15245 ENOG410849A acetyltransferase, (GNAT) family F9800_15255 ENOG4105K8R UPF0145 protein F9800_15270 ENOG4107RHR regulatoR F9800_15280 ENOG4105D9N nucleoside F9800_15285 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) F9800_15290 ENOG4105KG3 cytidine deaminase F9800_15335 ENOG4107RAQ aminopeptidase F9800_15345 ENOG4107R16 Multicopper oxidase F9800_15395 ENOG4108T5E Copper resistance protein F9800_15400 ENOG4105KTB nuclear export factor GLE1 F9800_15405 ENOG4107RT3 EamA-like transporter family F9800_15410 ENOG4105GZI Transcriptional regulator F9800_15415 ENOG4108Z40 Transcriptional regulator F9800_15420 ENOG4107ZXU DSBA oxidoreductase F9800_15425 ENOG4108TVJ Nitroreductase F9800_15430 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) F9800_15435 ENOG4106F5Q Membrane F9800_15440 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) F9800_15455 ENOG4105CKI cobalamin synthesis protein F9800_15465 ENOG4105C0Z ABC transporter F9800_15470 ENOG4108IV0 ABC, transporter F9800_15475 ENOG4105C32 Amino acid ABC transporter (Permease) F9800_15485 ENOG4105EGI Transcriptional regulator F9800_15515 ENOG4105C4M (Ubiquinol oxidase) subunit I F9800_15520 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii F9800_15525 ENOG4108JJ9 ABC, transporter F9800_15530 ENOG4108JJ8 (ABC) transporter F9800_15540 ENOG4105K64 Glycosyl transferase, family 2 F9800_15550 ENOG4108UT6 Transferase hexapeptide repeat containing protein F9800_15605 ENOG4105BZ1 (ABC) transporter F9800_15610 ENOG4105EFI regulatoR F9800_15615 ENOG4105BZU Histidine kinase F9800_15635 ENOG41075D4 Aminoglycoside 6-adenylyltransferase F9800_15640 ENOG4108ZJ4 polysaccharide deacetylase F9800_15660 ENOG4105D6E homoserine dehydrogenase F9800_15685 ENOG4108KGH TRANSCRIPTIONal F9800_15690 ENOG4107VMI polysaccharide deacetylase F9800_15700 ENOG4105KT7 mgtC SapB transporter F9800_15705 ENOG4105VRR gCN5-related N-acetyltransferase F9800_15715 ENOG4105DUU IucA IucC family protein F9800_15720 ENOG4105CEY Amp-dependent synthetase and ligase F9800_15735 ENOG4108WBH protein TIM barrel F9800_15740 ENOG4105YWU small acid-soluble spore protein F9800_15750 ENOG4108ZUB Lysine exporter protein (Lyse ygga) F9800_15755 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family F9800_15805 ENOG4105KRN Transcriptional regulator, abrb family F9800_15815 ENOG4105YVS arsR family transcriptional regulator F9800_15820 ENOG4105CPC Aldo Keto reductase F9800_15855 ENOG4105C8Q Methyl-accepting chemotaxis F9800_15875 ENOG4108K88 Membrane F9800_15880 ENOG4108WPJ Ferritin-like domain F9800_15895 ENOG4105DEN Luciferase family F9800_15910 ENOG4105VMI -acetyltransferase F9800_15915 ENOG4107QM2 Aldo Keto reductase F9800_15920 ENOG4105CKI cobalamin synthesis protein F9800_15930 ENOG4105DSE periplasmic solute binding protein F9800_15935 ENOG4105K4T epimerase F9800_15945 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) F9800_15970 ENOG4105CVJ phosphoglycerate mutase F9800_15990 ENOG4107T5V SNARE associated Golgi F9800_16005 ENOG4108PJD permease F9800_16015 ENOG4108S4H thioesterase Superfamily protein F9800_16025 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) F9800_16045 ENOG4105SXS Protein of unknown function (DUF456) F9800_16050 ENOG4105C37 (CBS) domain F9800_16080 ENOG4108Z7R Chaperone CsaA F9800_16100 ENOG4108ZRV stage ii sporulation protein p F9800_16110 ENOG4108VXD carboxy-peptidase F9800_16140 ENOG4108ZRV stage ii sporulation protein p F9800_16150 ENOG4108X4Q Hydrolase F9800_16155 ENOG41082F9 transcriptional regulator F9800_16160 ENOG4105D94 Major Facilitator Superfamily F9800_16170 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) F9800_16175 ENOG4107RBS Methyltransferase F9800_16190 ENOG41087PP glycosyltransferase MGT family F9800_16195 ENOG4108JYZ YitT family F9800_16200 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family F9800_16230 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) F9800_16250 ENOG4106PAW secretion accessory protein EsaA YueB F9800_16260 ENOG4106GSS Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host. Negative regulator of EsaC, which is a secretion substrate of the Ess pathway in many Staphylococcus strains. Not necessary for the production and secretion of EsxA or EsxB (By similarity) F9800_16385 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) F9800_16395 ENOG4105KBJ sporulation protein ytfj F9800_16420 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) F9800_16440 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) F9800_16445 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily F9800_16455 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein F9800_16460 ENOG4105EMN RNA polymerase sigma factor F9800_16470 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) F9800_16480 ENOG4105CNW domain protein F9800_16490 ENOG4108V06 Glutathione peroxidase F9800_16505 ENOG4105C7R Atpase associated with various cellular activities aaa_3 F9800_16515 ENOG4108IUE nitrate reductase beta subunit F9800_16520 ENOG4105R3A Nitrate reductase F9800_16530 ENOG4107V6Q Cyclic nucleotide-binding domain F9800_16535 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) F9800_16540 ENOG4105D06 uba thif-type nad fad binding protein F9800_16545 ENOG4105CVM Molybdenum cofactor synthesis domain protein F9800_16550 ENOG4108ZAF Molybdopterin F9800_16575 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein F9800_16580 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein F9800_16585 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) F9800_16590 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit F9800_16595 ENOG4108IFG nitrite reductase, (NAD(P)H) F9800_16600 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) F9800_16635 ENOG4105MCT stage V sporulation protein S F9800_16675 ENOG4105C5H ABC transporter F9800_16690 ENOG4108UUM single-stranded DNA-binding protein F9800_16715 ENOG4107YX5 Pfam:DUF548 F9800_16720 ENOG4105C75 arginyL-tRNA synthetase F9800_16750 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) F9800_16765 ENOG4105C5S asparaginyl-tRNA synthetase F9800_16770 ENOG4105C8J )-transporter F9800_16775 ENOG4108EF6 Proline imino-peptidase F9800_16790 ENOG4107XGZ Hydrolase F9800_16795 ENOG4105CY2 Citrate transporter F9800_16815 ENOG4105KD7 acetyltransferase F9800_16825 ENOG4105VMP Transcriptional regulator F9800_16830 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase F9800_16855 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 F9800_16885 ENOG4107RVG penicillin-binding protein F9800_16895 ENOG4105E9Q Acyl-transferase F9800_16900 ENOG4108UT2 hemolysin iii F9800_16910 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) F9800_16920 ENOG4108RCR degv family F9800_16930 ENOG4108KF3 Electron transport protein SCO1 SenC F9800_16935 ENOG4107Y70 Heat shock protein F9800_16940 ENOG4105CAQ asparagine synthetase F9800_16955 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase F9800_16960 ENOG4108MES Periplasmic binding protein F9800_16965 ENOG4105F0I Aminotransferase F9800_16995 ENOG4105D8X mechanosensitive ion channel F9800_17000 ENOG4105BZU Histidine kinase F9800_17005 ENOG4105WH1 Two component transcriptional regulator luxr family F9800_17010 ENOG4106KNT transcriptional regulator F9800_17015 ENOG4107ZY0 Phenazine biosynthesis-like protein F9800_17035 ENOG4105CMG Carbohydrate kinase F9800_17040 ENOG4105C6Z Gluconate F9800_17050 ENOG4108YV3 Protein of unknown function (DUF2711) F9800_17080 ENOG4108IJ8 ABC transporter F9800_17085 ENOG4105E90 ABC transporter F9800_17120 ENOG4105C37 (CBS) domain F9800_17145 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) F9800_17160 ENOG4107S4Y M20 DapE family protein YgeY F9800_17165 ENOG4108TSC N-acetyltransferase F9800_17170 ENOG4108JUB Transcriptional regulator F9800_17175 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein F9800_17220 ENOG410841Q phosphoesterase PA-phosphatase related protein F9800_17230 ENOG4105SZ6 Thioredoxin F9800_17275 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) F9800_17330 ENOG4105BZ4 penicillin-binding protein F9800_17340 ENOG4105CZM Major Facilitator F9800_17345 ENOG4105W8X HesB YadR YfhF-family protein F9800_17355 ENOG4105DXD 2-methylcitrate dehydratase F9800_17360 ENOG4105CR4 methylisocitrate lyase F9800_17365 ENOG4105C1G acyl-Coa dehydrogenase F9800_17370 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase F9800_17380 ENOG4105N14 lysine exporter protein LysE YggA F9800_17385 ENOG4105E39 Enoyl-CoA hydratase F9800_17400 ENOG4107RFY SbcCD D subunit F9800_17405 ENOG4105EYH Exonuclease F9800_17420 ENOG4105FCD Major Facilitator F9800_17425 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase F9800_17430 ENOG4105E4F Isochorismate synthase F9800_17435 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase F9800_17440 ENOG4105WQI isochorismatase F9800_17445 ENOG4105CEY Amp-dependent synthetase and ligase F9800_17450 ENOG4105WQT MbtH domain protein F9800_17455 ENOG4105C0R drug resistance transporter emrb qaca subfamily F9800_17470 ENOG4105K70 DNA-binding protein F9800_17490 ENOG4105BZG amino acid carrier protein F9800_17510 ENOG4105FE9 pseudouridine synthase F9800_17515 ENOG4105C22 threonyL-tRNA synthetase F9800_17520 ENOG4105C19 ABC transporter F9800_17555 ENOG41081I9 integral membrane protein F9800_17565 ENOG4108Y4K DNA-binding transcriptional activator F9800_17585 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) F9800_17595 ENOG4105EYF MMPL domain protein F9800_17620 ENOG4105WCN acetyltransferase F9800_17645 ENOG4105C1Q protoporphyrinogen oxidase F9800_17655 ENOG41068WN F9800_17685 ENOG4107V2S Transcriptional regulator F9800_17690 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) F9800_17705 ENOG4105DND Transcriptional regulator F9800_17710 ENOG4108RPX mosc domain containing protein F9800_17725 ENOG4105BZ1 (ABC) transporter F9800_17730 ENOG4105BZ1 (ABC) transporter F9800_17760 ENOG4108JCI Transcriptional regulator F9800_17790 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) F9800_17795 ENOG4108KPJ rna polymerase sigma factor F9800_17815 ENOG4105F32 YngK protein F9800_17840 ENOG4105RD7 BadF BadG BcrA BcrD F9800_17845 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) F9800_17850 ENOG4107STF Involved in phosphonate degradation (By similarity) F9800_17855 ENOG4105C7B Threonine dehydratase F9800_17860 ENOG4108INS Transcriptional regulator F9800_17875 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) F9800_17885 ENOG4105C1J atp-dependent rna helicase F9800_17890 ENOG41088CC tellurite resistance protein tehB F9800_17900 ENOG4108I0C methyltransferase F9800_17905 ENOG4107RA9 decarboxylase F9800_17945 ENOG4105CIN aminoacyl-histidine dipeptidase F9800_17970 ENOG4105KRN Transcriptional regulator, abrb family F9800_17980 ENOG4105EJ9 Membrane F9800_18025 ENOG4105W8Z 4'-phosphopantetheinyl transferase F9800_18035 ENOG4105CHR reductase F9800_18110 ENOG4108W0I acetyltransferase F9800_18115 ENOG4107QQG Dehydrogenase F9800_18120 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase F9800_18125 ENOG4108IAJ Nad-dependent epimerase dehydratase F9800_18130 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase F9800_18145 ENOG4105FJR Lmbe family F9800_18155 ENOG4105IIU Aminopeptidase F9800_18160 ENOG4108SC4 )-transporter F9800_18205 ENOG4108IMY Transcriptional regulator F9800_18225 ENOG4107VMI polysaccharide deacetylase F9800_18265 ENOG4107RVG penicillin-binding protein F9800_18280 ENOG4107RF6 penicillin-binding protein F9800_18290 ENOG4107RF6 penicillin-binding protein F9800_18300 ENOG4105DIN metallophosphoesterase F9800_18320 ENOG4107Z3H Transcriptional regulator, TetR family F9800_18335 ENOG4105C1G acyl-Coa dehydrogenase F9800_18340 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase F9800_18345 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit F9800_18350 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase F9800_18355 ENOG4105E39 Enoyl-CoA hydratase F9800_18360 ENOG4107QX3 carboxylase F9800_18365 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) F9800_18405 ENOG4105DZ1 carboxypeptidase F9800_18420 ENOG4105T9C HD domain F9800_18435 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) F9800_18455 ENOG41075H3 AraC family transcriptional regulator F9800_18485 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) F9800_18495 ENOG4105CHR reductase F9800_18500 ENOG4105KVH Transcriptional regulator F9800_18570 ENOG410900G Protein of unknown function (DUF421) F9800_18580 ENOG4108V4B ThiJ pfpI F9800_18590 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein F9800_18600 ENOG4105DK7 lysyl-tRNA synthetase F9800_18625 ENOG4106NZI LysR family Transcriptional regulator F9800_18630 ENOG4105CPC Aldo Keto reductase F9800_18675 ENOG4105D6E homoserine dehydrogenase F9800_18685 ENOG4105CPF Cell wall formation (By similarity) F9800_18690 ENOG4105ETU transcriptional activator (TenA F9800_18795 ENOG410667J hydrolase F9800_18800 ENOG4105BZU Histidine kinase F9800_18805 ENOG4107RF6 penicillin-binding protein F9800_18830 ENOG4108FPN Integrase F9800_18875 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein F9800_18890 ENOG4108VJ1 Transcriptional regulator (CarD family F9800_18955 ENOG4105KVH Transcriptional regulator F9800_18965 ENOG4105C4W S-formylglutathione hydrolase F9800_18975 ENOG4105D9M gamma-glutamylcysteine synthetase F9800_18990 ENOG41082BM Transcriptional regulator, arsr family F9800_19025 ENOG4105CVP deoxyribo-dipyrimidine photolyase F9800_19030 ENOG4108606 TspO/MBR family F9800_19045 ENOG4105WG9 Conserved Protein F9800_19060 ENOG4105ECP epimerase F9800_19070 ENOG4105XZV Protein of unknown function (DUF3243) F9800_19080 ENOG4105F6S Spore photoproduct lyase F9800_19105 ENOG4108JJB ABC transporter F9800_19120 ENOG4108HGU Histidine kinase F9800_19210 ENOG4105CB2 alcohol dehydrogenase F9800_19215 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase F9800_19220 ENOG4105CJN penicillin-binding protein F9800_19265 ENOG4107Y80 Major Facilitator superfamily F9800_19280 ENOG4107VXM glycerophosphoryl diester phosphodiesterase F9800_19305 ENOG4107Y9U Membrane F9800_19325 ENOG4105EGD dinuclear metal center protein, YbgI family F9800_19330 ENOG4105M6F mutator MutT protein F9800_19345 ENOG4105FCD Major Facilitator F9800_19360 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) F9800_19365 ENOG4108Z4K mutator MutT protein F9800_19390 ENOG4108XI2 Domain of unknown function (DUF1963) F9800_19410 ENOG4108NRW Phospholipase, patatin family F9800_19415 ENOG4105KWG Pfam:DUF1696 F9800_19440 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) F9800_19450 ENOG4105PKS Excinuclease abc c subunit domain protein F9800_19485 ENOG41087PP glycosyltransferase MGT family F9800_19505 ENOG4107VFR oxidoreductase F9800_19530 ENOG4105U0R haloacid dehalogenase-like hydrolase F9800_19535 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_19540 ENOG4105BZU Histidine kinase F9800_19560 ENOG4107WD8 ABC transporter, permease F9800_19575 ENOG4105DY8 decarboxylase F9800_19590 ENOG4108IUM Glycogen debranching enzyme F9800_19600 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic F9800_19620 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) F9800_19625 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) F9800_19630 ENOG4105FDR Membrane F9800_19635 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family F9800_19685 ENOG4105MSI germination protein ypeb F9800_19720 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) F9800_19725 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) F9800_19730 ENOG4107Z3H Transcriptional regulator, TetR family F9800_19755 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family F9800_19770 ENOG4105E98 transcriptional regulator DeoR family F9800_19785 ENOG41062ES Transcriptional regulator F9800_19805 ENOG4107QKR Dehydrogenase F9800_19815 ENOG4107RUY (E1 component), alpha subunit F9800_19825 ENOG4105E1F short-chain dehydrogenase reductase F9800_19830 ENOG4105RHY Pfam:UPF0157 F9800_19870 ENOG4107SQ8 Glycine betaine F9800_19875 ENOG4108IJ7 Glycine betaine F9800_19885 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) F9800_19900 ENOG4105E66 phosphoriboisomerase A F9800_19905 ENOG41082BV acetyltransferase F9800_19925 ENOG4108M1A Chitin-binding protein F9800_19930 ENOG41087PP glycosyltransferase MGT family F9800_19940 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) F9800_19955 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) F9800_19960 ENOG4105MSB protein, conserved in bacteria F9800_19985 ENOG4108Z7F N-acetyltransferase F9800_20010 ENOG4105KEG ribosomal-protein-alanine acetyltransferase F9800_20015 ENOG4105EEM helicase F9800_20030 ENOG4105C9U ATP-dependent DNA helicase RecQ F9800_20085 ENOG4108M1A Chitin-binding protein F9800_20105 ENOG4105BZG amino acid carrier protein F9800_20110 ENOG4105C26 Dehydrogenase F9800_20115 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) F9800_20125 ENOG4105CTU Proline racemase F9800_20130 ENOG41080HI glycine oxidase F9800_20140 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein F9800_20175 ENOG4107T5V SNARE associated Golgi F9800_20185 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD F9800_20200 ENOG4105DTQ mandelate racemase muconate lactonizing F9800_20215 ENOG4107SET aldo keto reductase F9800_20250 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) F9800_20255 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) F9800_20260 ENOG4105BZU Histidine kinase F9800_20265 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_20290 ENOG4105DPN Oligoendopeptidase f F9800_20295 ENOG4105EPR degv family F9800_20355 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) F9800_20360 ENOG4106K7D Major facilitator family transporter F9800_20385 ENOG4107BMA Transglycosylase associated protein F9800_20400 ENOG41089UC methyltransferase, type 11 F9800_20435 ENOG4105CHM Aminotransferase F9800_20485 ENOG4105C02 permease F9800_20500 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component F9800_20505 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein F9800_20510 ENOG4105D7T ABC transporter F9800_20535 ENOG4108AQF aminoglycoside N(3)-acetyltransferase F9800_20570 ENOG4107VC0 DNA alkylation repair enzyme F9800_20575 ENOG4105C6T cysteine synthase F9800_20580 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase F9800_20595 ENOG4107VMI polysaccharide deacetylase F9800_20615 ENOG4108ZCF integral membrane protein F9800_20620 ENOG4105E0M Sulfatase F9800_20625 ENOG4105C5H ABC transporter F9800_20630 ENOG4105EYF MMPL domain protein F9800_20635 ENOG41082JN Transcriptional regulator F9800_20660 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase F9800_20665 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase F9800_20705 ENOG41069ER domain protein F9800_20735 ENOG4105D4B ABC, transporter F9800_20745 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane F9800_20755 ENOG4105DKT Transcriptional regulator F9800_20760 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) F9800_20770 ENOG41061GT Aldolase F9800_20785 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) F9800_20815 ENOG4105II7 pyrroline-5-carboxylate reductase F9800_20825 ENOG4107258 Transcriptional regulator F9800_20845 ENOG4105E0Y RtcB Protein F9800_20850 ENOG4105ECK Fatty Acid Desaturase F9800_20860 ENOG4107RBI VanW family F9800_20865 ENOG4105G6Z alkaline phosphatase F9800_20875 ENOG4105VMP Transcriptional regulator F9800_20895 ENOG41068WN F9800_20930 ENOG4105C7R Atpase associated with various cellular activities aaa_3 F9800_20955 ENOG4105C8Y Acetylornithine aminotransferase F9800_20990 ENOG41090AA F9800_21015 ENOG4108TVJ Nitroreductase F9800_21020 ENOG4105FS7 Transcriptional regulator F9800_21040 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) F9800_21045 ENOG4105WEC Molybdate metabolism regulator F9800_21050 ENOG4105CMR udp-glucose 4-epimerase F9800_21055 ENOG4105C19 ABC transporter F9800_21080 ENOG4108XET gCN5-related N-acetyltransferase F9800_21090 ENOG4105E09 nadh pyrophosphatase F9800_21095 ENOG4108PCN EamA-like transporter family F9800_21145 ENOG410635A Membrane F9800_21155 ENOG4108IQI permease F9800_21210 ENOG4108VJ1 Transcriptional regulator (CarD family F9800_21220 ENOG4105BZU Histidine kinase F9800_21250 ENOG4107RF6 penicillin-binding protein F9800_21255 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) F9800_21285 ENOG4105P4J Allophanate hydrolase, subunit 1 F9800_21290 ENOG4107258 Transcriptional regulator F9800_21300 ENOG4106N3A copper homeostasis protein cutc F9800_21305 ENOG4108ZHR arsR family transcriptional regulator F9800_21315 ENOG4105FDT acyl-CoA dehydrogenase F9800_21330 ENOG4105DWD nucleoside recognition domain protein F9800_21370 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) F9800_21400 ENOG4105E2A Dehydrogenase F9800_21410 ENOG4108IJ0 Aspartate ammonia-lyase F9800_21420 ENOG4108IMY Transcriptional regulator F9800_21440 ENOG4108B31 Spore germination protein F9800_21450 ENOG4105BZU Histidine kinase F9800_21475 ENOG41075H3 AraC family transcriptional regulator F9800_21490 ENOG4105YWU small acid-soluble spore protein F9800_21495 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) F9800_21500 ENOG4105CUB amino acid F9800_21505 ENOG4105II7 pyrroline-5-carboxylate reductase F9800_21515 ENOG4108Q8B Spore germination protein F9800_21550 ENOG4106A3M Cytochrome p-450 F9800_21570 ENOG4105CGH 5'-nucleotidase F9800_21580 ENOG4105CHJ isochorismatase hydrolase F9800_21605 ENOG41090MY MarR family Transcriptional regulator F9800_21635 ENOG4105F6J Alpha beta hydrolase fold F9800_21650 ENOG4108606 TspO/MBR family F9800_21655 ENOG4105CVP deoxyribo-dipyrimidine photolyase F9800_21670 ENOG4108TWJ NADH dehydrogenase subunit 5 F9800_21675 ENOG4105GPN Uncharacterized conserved protein (DUF2294) F9800_21680 ENOG4107VMI polysaccharide deacetylase F9800_21695 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase F9800_21700 ENOG4105DSE periplasmic solute binding protein F9800_21705 ENOG4105CC5 ABC transporter F9800_21710 ENOG4105DIK (ABC) transporter F9800_21730 ENOG4105D6J arsenicaL-resistance protein F9800_21735 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase F9800_21740 ENOG41085FC arsR family transcriptional regulator F9800_21755 ENOG4105EGI Transcriptional regulator F9800_21795 ENOG4105VZ8 Transcriptional regulator F9800_21810 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) F9800_21820 ENOG4107P5I polyketide synthase F9800_21825 ENOG4108IG5 Transcriptional regulator F9800_21830 ENOG4105CHR reductase F9800_21835 ENOG4108YXU transcriptional regulator AsnC family F9800_21880 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_21885 ENOG4105BZU Histidine kinase F9800_21925 ENOG4105DNP FAD linked oxidase domain protein F9800_21940 ENOG4105C19 ABC transporter F9800_21975 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) F9800_21980 ENOG4105C0R drug resistance transporter emrb qaca subfamily F9800_21990 ENOG4105K6H D-cysteine desulfhydrase F9800_22010 ENOG4105JQZ Methyltransferase F9800_22030 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) F9800_22050 ENOG4105BZU Histidine kinase F9800_22065 ENOG4108U05 Transcriptional regulator F9800_22070 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 F9800_22080 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) F9800_22105 ENOG4108JQ1 Dehydrogenase F9800_22110 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) F9800_22125 ENOG41082W1 Cupin 2, conserved barrel domain protein F9800_22135 ENOG410874W AraC family transcriptional regulator F9800_22155 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase F9800_22165 ENOG4108IG5 Transcriptional regulator F9800_22275 ENOG4107EV6 Inherit from COG: YD repeat protein F9800_22300 ENOG4108VXD carboxy-peptidase F9800_22305 ENOG4105PNM synthesis protein F9800_22315 ENOG4108ISG Major Facilitator F9800_22330 ENOG4107MII Sugar-specific transcriptional regulator TrmB F9800_22335 ENOG4105CZM Major Facilitator F9800_22345 ENOG4105CRW Short chain fatty acid transporter F9800_22360 ENOG4105DYS nad(p)h dehydrogenase (quinone) F9800_22420 ENOG4108K8S endonuclease I F9800_22430 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) F9800_22435 ENOG4108Z66 YbaK ebsC protein F9800_22455 ENOG4105KVH Transcriptional regulator F9800_22460 ENOG4108RCM Nitroreductase F9800_22490 ENOG4108PSK reductase F9800_22555 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase F9800_22560 ENOG4105DKQ ROK family F9800_22565 ENOG4106UW1 Major Facilitator superfamily F9800_22570 ENOG4108UW5 maltose o-acetyltransferase F9800_22580 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) F9800_22585 ENOG4105C31 Tryptophanyl-tRNA synthetase F9800_22620 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) F9800_22630 ENOG4105EV4 Multidrug resistance protein mdtH F9800_22660 ENOG4105C37 (CBS) domain F9800_22685 ENOG4105DDN Pentapeptide repeat-containing protein F9800_22690 ENOG4105XDF Protein of unknown function (DUF1272) F9800_22695 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) F9800_22700 ENOG4105CMG Carbohydrate kinase F9800_22705 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) F9800_22715 ENOG4105CV1 Transketolase (EC 2.2.1.1) F9800_22720 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase F9800_22740 ENOG4105C44 Serine transporter F9800_22770 ENOG4105KVH Transcriptional regulator F9800_22775 ENOG4108TZY GntR Family Transcriptional Regulator F9800_22780 ENOG4105D9R oxidoreductase F9800_22825 ENOG4105JAB phenazine biosynthesis protein, phzf family F9800_22840 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein F9800_22845 ENOG4105KVH Transcriptional regulator F9800_22850 ENOG4107SCK Monooxygenase F9800_22865 ENOG4108ZJ4 polysaccharide deacetylase F9800_22920 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) F9800_22960 ENOG4105H3G oxidoreductase F9800_22995 ENOG4105CIS alcohol dehydrogenase F9800_23035 ENOG4108TN2 lmbE family F9800_23045 ENOG4107R3E Citrate transporter F9800_23055 ENOG4105WCN acetyltransferase F9800_23060 ENOG4105NX3 Membrane F9800_23080 ENOG4107CUJ Protein of unknown function (DUF2690) F9800_23090 ENOG4107V2S Transcriptional regulator F9800_23110 ENOG4105C98 muts2 protein F9800_23120 ENOG4105E5K Alpha-amylase F9800_23125 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase F9800_23130 ENOG4105DPN Oligoendopeptidase f F9800_23165 ENOG4108A04 Beta-lactamase F9800_23190 ENOG4107VXM glycerophosphoryl diester phosphodiesterase F9800_23200 ENOG41082BM Transcriptional regulator, arsr family F9800_23205 ENOG4105CIS alcohol dehydrogenase F9800_23225 ENOG4105C09 Bile acid F9800_23230 ENOG4105CQB FAD linked oxidase domain protein F9800_23250 ENOG4105CEP NADH dehydrogenase F9800_23275 ENOG4105D2T synthase F9800_23290 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) F9800_23295 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase F9800_23300 ENOG4105C1B dTDP-glucose 4-6-dehydratase F9800_23305 ENOG4105C5E polysaccharide biosynthesis protein F9800_23330 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C F9800_23335 ENOG4108M1A Chitin-binding protein F9800_23345 ENOG4105E1K spore germination protein F9800_23365 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase F9800_23380 ENOG4105FAW cDP-glucose 4,6-dehydratase F9800_23425 ENOG4105BZU Histidine kinase F9800_23435 ENOG41067SE Tetr family transcriptional regulator F9800_23500 ENOG4105XSJ toxin secretion phage lysis holin F9800_23560 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) F9800_23570 ENOG4105CAR Terminase, large subunit F9800_23715 ENOG4108IMY Transcriptional regulator F9800_23750 ENOG4108VXD carboxy-peptidase F9800_23755 ENOG4107DUR UPF0457 protein F9800_23775 ENOG4105BZU Histidine kinase F9800_23785 ENOG4105KT7 mgtC SapB transporter F9800_23795 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase F9800_23800 ENOG41073R8 VanW family F9800_23810 ENOG4108R1P F9800_23825 ENOG4105VEQ Cold shock protein F9800_23845 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) F9800_23865 ENOG410904N short-chain dehydrogenase reductase F9800_23875 ENOG4106IQC argininosuccinate lyase F9800_23890 ENOG4108IA2 Sodium pantothenate symporter F9800_23900 ENOG4105C26 Dehydrogenase F9800_23905 ENOG4105CHR reductase F9800_23915 ENOG4105EWU Squalene--hopene cyclase F9800_23925 ENOG4105FR1 rard protein F9800_23930 ENOG410696E Membrane F9800_23945 ENOG4105D1F ATP-binding protein F9800_23955 ENOG4108ZAF Molybdopterin F9800_23960 ENOG4105CVM Molybdenum cofactor synthesis domain protein F9800_23965 ENOG4105D06 uba thif-type nad fad binding protein F9800_23970 ENOG4105TMB Formate nitrite transporter F9800_23980 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) F9800_23985 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) F9800_24035 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase F9800_24135 ENOG4108C33 Resolvase F9800_24160 ENOG4105WXW Antirepressor F9800_24170 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_24210 ENOG4108PNI recT protein F9800_24215 ENOG4108NF7 phage-type endonuclease F9800_24265 ENOG4108JB9 formate dehydrogenase F9800_24340 ENOG4107QJT sodium dicarboxylate symporter F9800_24345 ENOG4108KGH TRANSCRIPTIONal F9800_24355 ENOG4105EMN RNA polymerase sigma factor F9800_24365 ENOG4105CIG ABC transporter F9800_24385 ENOG4105D9R oxidoreductase F9800_24395 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) F9800_24400 ENOG4105K4P CoA-binding domain protein F9800_24405 ENOG4105C0H protease F9800_24410 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_24420 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase F9800_24425 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) F9800_24430 ENOG4105W8X HesB YadR YfhF-family protein F9800_24455 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) F9800_24460 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen F9800_24470 ENOG4108JJB ABC transporter F9800_24475 ENOG4108I0Z Aconitate hydratase F9800_24505 ENOG4105E5W Transporter F9800_24515 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) F9800_24535 ENOG4107F3J Amp-dependent synthetase and ligase F9800_24540 ENOG4107ZYJ bioY protein F9800_24545 ENOG4105CEY Amp-dependent synthetase and ligase F9800_24550 ENOG4108IMY Transcriptional regulator F9800_24585 ENOG4107AYK membrAne F9800_24600 ENOG4105BZU Histidine kinase F9800_24605 ENOG4105FBA Phospholipase Carboxylesterase F9800_24610 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase F9800_24615 ENOG4105CK7 Sodium proline symporter F9800_24625 ENOG4105CBC glutamate synthase F9800_24630 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase F9800_24635 ENOG4108VJ1 Transcriptional regulator (CarD family F9800_24640 ENOG4108903 Formimidoylglutamase F9800_24700 ENOG4107QIV Cytochrome c biogenesis protein F9800_24715 ENOG4105CH2 amidohydrolase F9800_24725 ENOG4105CJ1 ABC, transporter F9800_24745 ENOG4107RSM transcriptional regulator F9800_24750 ENOG4105VAW lrga family F9800_24755 ENOG41067MG lrgb family F9800_24795 ENOG4105BZ1 (ABC) transporter F9800_24800 ENOG4105BZ1 (ABC) transporter F9800_24835 ENOG4108HW3 (ABC) transporter F9800_24840 ENOG4105CGH 5'-nucleotidase F9800_24850 ENOG4108SVB resolvase F9800_24870 ENOG4105K7K Transcriptional regulator F9800_24880 ENOG4105E4C Lytic transglycosylase catalytic F9800_24885 ENOG41065S2 pneumococcal vaccine antigen F9800_24920 ENOG4105C5F glutamine synthetase F9800_24925 ENOG4105KV4 Transcriptional regulator F9800_24930 ENOG4105CXI aluminum resistance protein F9800_24935 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) F9800_24940 ENOG4105EN6 Membrane F9800_24945 ENOG4106F1P AAA ATPase, central domain protein F9800_24975 ENOG41069ER domain protein F9800_24980 ENOG4105DM4 PTS System F9800_24985 ENOG4105DE4 1-phosphofructokinase F9800_24990 ENOG4105E98 transcriptional regulator DeoR family F9800_24995 ENOG4107QW4 alcohol dehydrogenase F9800_25000 ENOG4108SJC Membrane F9800_25010 ENOG4105C85 amino acid F9800_25035 ENOG4105TMB Formate nitrite transporter F9800_25040 ENOG4105K70 DNA-binding protein F9800_25050 ENOG4105C59 p-type ATPase F9800_25055 ENOG410681U heavy metal transport detoxification protein F9800_25060 ENOG4105VPX protein, conserved in bacteria F9800_25080 ENOG4105NIV Esterase F9800_25085 ENOG4105E0A ABC, transporter F9800_25105 ENOG4105CGK Exodeoxyribonuclease III F9800_25115 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) F9800_25120 ENOG4105D03 DNA-3-methyladenine glycosylase II F9800_25150 ENOG4105BZU Histidine kinase F9800_25190 ENOG41067MG lrgb family F9800_25215 ENOG4105C8Q Methyl-accepting chemotaxis F9800_25220 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C F9800_25230 ENOG4105F0V Cell wall hydrolase F9800_25245 ENOG4105E0M Sulfatase F9800_25250 ENOG410890F Dynamin family F9800_25285 ENOG4105DQU oxidoreductase, subunit beta F9800_25290 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein F9800_25295 ENOG4108IGT Dipeptidase F9800_25300 ENOG4105MCT stage V sporulation protein S F9800_25305 ENOG4105D48 metallophosphoesterase F9800_25325 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase F9800_25340 ENOG4105XZV Protein of unknown function (DUF3243) F9800_25345 ENOG4108RKS Short-chain dehydrogenase reductase Sdr F9800_25365 ENOG4105UIB (ABC) transporter F9800_25370 ENOG4108JQ9 ABC transporter F9800_25375 ENOG4105DIH basic membrane F9800_25380 ENOG4105FDP GntR family transcriptional regulator F9800_25390 ENOG4105CNU cell division protein FtsK F9800_25400 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit F9800_25410 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) F9800_25420 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) F9800_25425 ENOG4108S0H Dipicolinic acid synthetase, b subunit F9800_25430 ENOG4108IBT Inherit from COG: transposase F9800_25590 ENOG4105CDU Replicative dna helicase F9800_25635 ENOG4108IMY Transcriptional regulator F9800_25660 ENOG4105E35 Dipicolinate synthase subunit A F9800_25670 ENOG4105C1V Peptidase, M16 F9800_25690 ENOG4105DTN riboflavin biosynthesis protein ribF F9800_25705 ENOG4105W7A Protein of unknown function (DUF503) F9800_25715 ENOG4105VHM ribosomal protein F9800_25720 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination F9800_25725 ENOG4105CHV Transcription elongation factor NusA F9800_25735 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) F9800_25745 ENOG4105DZP Membrane-associated zinc metalloprotease F9800_25750 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) F9800_25755 ENOG4105KNE Phosphatidate cytidylyltransferase F9800_25760 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) F9800_25770 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) F9800_25800 ENOG4108HE4 integrase family F9800_25810 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) F9800_25815 ENOG4105C79 DNA protecting protein DprA F9800_25820 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha F9800_25835 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) F9800_25860 ENOG4105VB6 UPF0109 protein F9800_25880 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) F9800_25885 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) F9800_25900 ENOG4105CHR reductase F9800_25905 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase F9800_25920 ENOG4105CB5 ATP-dependent DNA helicase recG F9800_25925 ENOG4105DP4 dak2 domain fusion protein ylov F9800_25930 ENOG4108ZAA Alkaline-shock protein F9800_25945 ENOG4105FJ0 thiamine F9800_25950 ENOG4105DJV ribulose-phosphate 3-epimerase F9800_25955 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) F9800_25960 ENOG4105D9P serine threonine protein kinase F9800_25965 ENOG4108ZF3 Phosphatase F9800_25975 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B F9800_25990 ENOG4105C25 Primosomal protein n' F9800_25995 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase F9800_26015 ENOG4105DSJ YicC domain protein F9800_26025 ENOG4105F23 Fibronectin-binding protein F9800_26030 ENOG4105DC7 peptidase M24 F9800_26110 ENOG4105C34 Pseudouridine synthase F9800_26125 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) F9800_26135 ENOG4105DBK s4 domain protein F9800_26140 ENOG41067XK integral membrane protein F9800_26150 ENOG4105DFA alanine racemase domain protein F9800_26155 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase F9800_26160 ENOG4105WR5 sporulation protein, YlmC YmxH family F9800_26170 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_26180 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) F9800_26185 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) F9800_26195 ENOG4105D4A Cell wall formation (By similarity) F9800_26200 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) F9800_26205 ENOG4105CNI cell division protein FtsW F9800_26220 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) F9800_26225 ENOG4105CJN penicillin-binding protein F9800_26230 ENOG4105CJN penicillin-binding protein F9800_26270 ENOG4105KNH Nucleic acid-binding protein F9800_26280 ENOG41063PX domain protein F9800_26285 ENOG4105D78 K07001 NTE family protein F9800_26290 ENOG4105H20 Sporulation integral membrane protein YlbJ F9800_26300 ENOG4106H78 methyltransferase F9800_26320 ENOG4107TB6 phosphoglycerate mutase F9800_26335 ENOG4106UY4 Inherit from COG: Scp-like extracellular F9800_26385 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) F9800_26395 ENOG4105CNI cell division protein FtsW F9800_26410 ENOG4108IAB Phoh family F9800_26430 ENOG4105QA2 F9800_26435 ENOG4105CI3 gtp-binding protein typa F9800_26445 ENOG4105ECY inositol monophosphatase F9800_26465 ENOG4105CXN decarboxylase F9800_26515 ENOG4105CPP Dehydrogenase, E1 component F9800_26530 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) F9800_26535 ENOG4108X4Q Hydrolase F9800_26550 ENOG4105CN5 Metallo-Beta-Lactamase F9800_26555 ENOG4107ZYR domain protein F9800_26590 ENOG4108XRC Protein of unknown function (DUF458) F9800_26595 ENOG4107IN1 Protein of unknown function (DUF1797) F9800_26610 ENOG4105EPM Diguanylate phosphodiesterase F9800_26615 ENOG4105K6S Short-chain dehydrogenase reductase Sdr F9800_26630 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) F9800_26640 ENOG4105UIN F9800_26695 ENOG4108HGU Histidine kinase F9800_26705 ENOG4105CHM Aminotransferase F9800_26710 ENOG4105FKQ transcriptional regulator F9800_26715 ENOG4105EG2 ABC transporter, permease F9800_26725 ENOG4107FKK extracellular solute-binding protein family 1 F9800_26735 ENOG4105CG3 alpha amylase, catalytic region F9800_26780 ENOG4105CHU acetyl-coa acetyltransferase F9800_26815 ENOG4105K7K Transcriptional regulator F9800_26820 ENOG4105DTD Dehydrogenase F9800_26840 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase F9800_26865 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) F9800_26880 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase F9800_26890 ENOG4105BZU Histidine kinase F9800_26910 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) F9800_26925 ENOG4105CID antiterminator F9800_26935 ENOG4105FDP GntR family transcriptional regulator F9800_26945 ENOG4105CE4 GlcNAc 6-P deacetylase F9800_26985 ENOG4107ZE5 PPIases accelerate the folding of proteins F9800_26990 ENOG4105PTM secreted protein F9800_26995 ENOG4105J7I hydrolase F9800_27005 ENOG4105G6R Stage v sporulation protein ae F9800_27015 ENOG4105CZ3 stage V sporulation protein ad F9800_27020 ENOG41090VF Stage v sporulation protein ac F9800_27040 ENOG4105C8J )-transporter F9800_27045 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_27055 ENOG41082AN stage II sporulation protein F9800_27060 ENOG4105DZ1 carboxypeptidase F9800_27070 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family F9800_27075 ENOG4105DVE abc transporter atp-binding protein F9800_27110 ENOG4105D7N magnesium and cobalt transport protein CorA F9800_27135 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) F9800_27145 ENOG4105I3K Ferric uptake regulator, Fur family F9800_27150 ENOG4105MZ9 stage II sporulation protein m F9800_27170 ENOG4105CPC Aldo Keto reductase F9800_27180 ENOG4105RHY Pfam:UPF0157 F9800_27200 ENOG4107SKW Inherit from COG: Alpha beta hydrolase F9800_27210 ENOG4105ETE Transcriptional regulator (LacI family F9800_27215 ENOG4108YM7 Gcn5-related n-acetyltransferase F9800_27235 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) F9800_27240 ENOG4108R6K riboflavin synthase, subunit alpha F9800_27265 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) F9800_27270 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) F9800_27285 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) F9800_27295 ENOG4105DFD Na H antiporter F9800_27300 ENOG4105CGH 5'-nucleotidase F9800_27325 ENOG4105DBV ornithine carbamoyltransferase F9800_27340 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) F9800_27355 ENOG4108IXY short-chain dehydrogenase reductase F9800_27360 ENOG41069FQ Metallo-beta-lactamase superfamily F9800_27365 ENOG4105II7 pyrroline-5-carboxylate reductase F9800_27370 ENOG4105EJQ L-serine dehydratase F9800_27400 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic F9800_27415 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) F9800_27420 ENOG4105D9U N-acetyltransferase F9800_27435 ENOG4108VZI ErfK ybiS ycfS ynhG family protein F9800_27440 ENOG4108QEG Membrane F9800_27450 ENOG4105E5Q amino acid AbC transporter F9800_27455 ENOG4108HW3 (ABC) transporter F9800_27465 ENOG4105G7B Protein of unknown function (DUF2992) F9800_27475 ENOG4108QY0 Membrane F9800_27485 ENOG4105C7S Dehydrogenase F9800_27490 ENOG4105CPP Dehydrogenase, E1 component F9800_27510 ENOG4107RDP Dehydrogenase F9800_27525 ENOG4108JUB Transcriptional regulator F9800_27535 ENOG4108QXE glycerophosphoryl diester phosphodiesterase F9800_27585 ENOG4108C33 Resolvase F9800_27625 ENOG4107QQR Sporulation F9800_27635 ENOG4105S1Z Stage IV sporulation protein B F9800_27640 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) F9800_27645 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) F9800_27650 ENOG4105DX0 Hemolysin A F9800_27660 ENOG4105CTB Polyprenyl synthetase F9800_27685 ENOG4108ZSR alkaline shock protein F9800_27690 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase F9800_27715 ENOG410644B Stage III sporulation protein af F9800_27725 ENOG4105KQ4 Stage iii sporulation protein ad F9800_27730 ENOG4108CQH stage III sporulation protein AC F9800_27735 ENOG4105KR5 Stage iii sporulation protein F9800_27740 ENOG4105CD2 stage iii sporulation protein aa F9800_27765 ENOG4105DC7 peptidase M24 F9800_27780 ENOG4105CBJ Metal-dependent enzyme F9800_27790 ENOG4107YBY Hydrolase F9800_27820 ENOG41082GG biotin lipoate A B protein ligase F9800_27825 ENOG4105WZW rhodanese family F9800_27850 ENOG41080TC multidrug resistance protein F9800_27895 ENOG4105C0D helicase F9800_27925 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) F9800_27980 ENOG4107R6U sodium dicarboxylate symporter F9800_28015 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) F9800_28020 ENOG4105C3R Methionine synthase F9800_28030 ENOG4105C28 cystathionine F9800_28035 ENOG4105C28 cystathionine F9800_28055 ENOG4105C5X domain protein F9800_28065 ENOG4105DKQ ROK family F9800_28075 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase F9800_28090 ENOG4108UTW Plays a role in the regulation of phosphate uptake F9800_28095 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) F9800_28100 ENOG4105C8U phosphate abc transporter F9800_28105 ENOG4105C8U phosphate abc transporter F9800_28115 ENOG4107RF6 penicillin-binding protein F9800_28155 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase F9800_28250 ENOG4108C33 Resolvase F9800_28325 ENOG4108IMY Transcriptional regulator F9800_28355 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) F9800_28380 ENOG4105N80 Ferric uptake regulator, Fur family F9800_28390 ENOG4105FDK ABC transporter F9800_28395 ENOG4108JYZ YitT family F9800_28400 ENOG41069ZM Protein of unknown function (DUF2624) F9800_28425 ENOG4105EGD dinuclear metal center protein, YbgI family F9800_28440 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_28445 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) F9800_28470 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) F9800_28475 ENOG4105KG3 cytidine deaminase F9800_28480 ENOG4107YR5 Diacylglycerol kinase F9800_28490 ENOG4105CTJ Metal Dependent Phosphohydrolase F9800_28495 ENOG4105C9A Phoh family F9800_28505 ENOG41068P3 sporulation protein YqfC F9800_28515 ENOG4105KTH gatB Yqey F9800_28525 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) F9800_28530 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) F9800_28560 ENOG4105CSA Coproporphyrinogen iii oxidase F9800_28565 ENOG4105KVH Transcriptional regulator F9800_28590 ENOG4105TQK DNA polymerase iii, delta' subunit F9800_28600 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 F9800_28605 ENOG4108UK2 deaminase F9800_28610 ENOG4105KQC Competence protein F9800_28620 ENOG4105DXX methyltransferase F9800_28630 ENOG4108WF2 Metal Dependent Phosphohydrolase F9800_28640 ENOG410812S Rna-binding protein F9800_28650 ENOG4105CQW ribosome biogenesis GTPase YqeH F9800_28655 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase F9800_28670 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_28690 ENOG4108TVJ Nitroreductase F9800_28705 ENOG4105G6Z alkaline phosphatase F9800_28710 ENOG4105KEG ribosomal-protein-alanine acetyltransferase F9800_28715 ENOG4108MUZ hydrolase F9800_28750 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin F9800_28755 ENOG4105MIR Phenylalanine 4-monooxygenase F9800_28765 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase F9800_28805 ENOG4105S6R Iron-hydroxamate transporter permease subunit F9800_28810 ENOG4108V5C ABC transporter F9800_28825 ENOG4108EKI Dehydrogenase F9800_28830 ENOG4105C28 cystathionine F9800_28860 ENOG4107XRG penicillin-binding protein F9800_28870 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) F9800_28880 ENOG4105CFP Peptidase U32 F9800_28885 ENOG4105XYU peptidase (U32 family) F9800_28890 ENOG4108VQJ O-methyltransferase F9800_28895 ENOG4105HHA aminodeoxychorismate lyase F9800_28915 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) F9800_28925 ENOG4105C02 permease F9800_28940 ENOG41060CR F9800_28945 ENOG4105C7H Helicase, RecD TraA family F9800_28955 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) F9800_28960 ENOG4105C3J Cysteine desulfurase F9800_28970 ENOG4105D1H recombination factor protein RarA F9800_28975 ENOG4108VCI transcription factor, rsfa family F9800_28985 ENOG4105CUZ uba thif-type nad fad binding protein F9800_29000 ENOG4105CUT histidyl-tRNA synthetase F9800_29015 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) F9800_29025 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) F9800_29030 ENOG41076HS cation diffusion facilitator family transporter F9800_29035 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) F9800_29045 ENOG4105CKP Polysaccharide Biosynthesis Protein F9800_29050 ENOG4108QG2 Membrane F9800_29060 ENOG4105VIE preprotein translocase, subunit YajC F9800_29075 ENOG41061AI Protein of unknown function (DUF2905) F9800_29090 ENOG4108HUF Transporter F9800_29120 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase F9800_29125 ENOG4108IYU L-aspartate oxidase F9800_29140 ENOG4108RPX mosc domain containing protein F9800_29150 ENOG4105CQC Prephenate dehydratase F9800_29170 ENOG4105EWM Histidine kinase F9800_29195 ENOG4105X36 (ribosomal) protein F9800_29205 ENOG4105C03 ribonuclease F9800_29220 ENOG4107QMS site-determining protein F9800_29235 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) F9800_29240 ENOG4105DFF Rod shape-determining protein mreb F9800_29260 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase F9800_29265 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) F9800_29275 ENOG41068KH stage VI sporulation protein D F9800_29285 ENOG4105D52 delta-aminolevulinic acid dehydratase F9800_29310 ENOG4105K56 Transcriptional regulator F9800_29330 ENOG4108IUQ atp-dependent protease F9800_29355 ENOG4108QCI YvbH-like oligomerisation region F9800_29380 ENOG4105M59 Phosphodiesterase, mj0936 family F9800_29395 ENOG4108XJQ germination protein F9800_29405 ENOG4108PCX Major Facilitator F9800_29415 ENOG4105KBX Transcriptional regulator, TetR family F9800_29425 ENOG4105PFC Transcriptional regulator F9800_29435 ENOG4105DZC cytosine deaminase F9800_29440 ENOG41067S9 phage shock protein C, PspC F9800_29445 ENOG4108JCI Transcriptional regulator F9800_29455 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) F9800_29460 ENOG4108Z40 Transcriptional regulator F9800_29465 ENOG4105RHA ABC transporter, permease F9800_29470 ENOG4108IUX (ABC) transporter F9800_29475 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family F9800_29480 ENOG4105ER2 Ompa motb domain protein F9800_29485 ENOG4105E14 MotA TolQ exbB proton channel F9800_29490 ENOG4108VXD carboxy-peptidase F9800_29500 ENOG4105E33 succinate dehydrogenase F9800_29510 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit F9800_29525 ENOG4105K63 Thioredoxin F9800_29530 ENOG4105C10 Electron transfer flavoprotein F9800_29535 ENOG4105BZJ Electron transfer flavoprotein F9800_29540 ENOG41060WC Enoyl-CoA hydratase F9800_29545 ENOG4107Z3H Transcriptional regulator, TetR family F9800_29550 ENOG4105CEY Amp-dependent synthetase and ligase F9800_29560 ENOG4105J76 Periplasmic binding protein F9800_29565 ENOG4105S6R Iron-hydroxamate transporter permease subunit F9800_29600 ENOG4105DPZ Two component transcriptional regulator (Winged helix family F9800_29610 ENOG4105DR4 Methyltransferase F9800_29620 ENOG4105KFN sortase, SrtB family F9800_29625 ENOG4105E0A ABC, transporter F9800_29640 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) F9800_29650 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) F9800_29660 ENOG4105FE9 pseudouridine synthase F9800_29670 ENOG4105DCG PHP domain protein F9800_29685 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) F9800_29700 ENOG4105C5S asparaginyl-tRNA synthetase F9800_29705 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) F9800_29715 ENOG4108RWN rrna methyltransferase F9800_29740 ENOG4105C0R drug resistance transporter emrb qaca subfamily F9800_29745 ENOG4105CW7 secretion protein, HlyD family F9800_29750 ENOG4108JGH Tetr family transcriptional regulator F9800_29755 ENOG4105CN9 Peptidase m42 family protein F9800_29775 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) F9800_29780 ENOG4105C22 threonyL-tRNA synthetase F9800_29785 ENOG4108TDW sporulation protein YtxC F9800_29810 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) F9800_29815 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase F9800_29820 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) F9800_29830 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) F9800_29835 ENOG4105C2M dna polymerase I F9800_29840 ENOG4105BZU Histidine kinase F9800_29845 ENOG4105DPZ Two component transcriptional regulator (Winged helix family F9800_29865 ENOG4108HMX isocitrate dehydrogenase (NADP) F9800_29870 ENOG4105BZN citrate synthase F9800_29885 ENOG4108REF Sporulation integral membrane protein ytvi F9800_29890 ENOG4105FS0 cytoplasmic membrane protein F9800_29915 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family F9800_29920 ENOG4105C6K Malic enzyme F9800_29925 ENOG4105C0B DNA polymerase III (alpha subunit) F9800_29930 ENOG4105VV2 F9800_29940 ENOG4105SFS phosphoesterase RecJ domain protein F9800_29965 ENOG4105DC7 peptidase M24 F9800_30000 ENOG4105Z7P Acetyltransferase (GNAT) family F9800_30005 ENOG41082W1 Cupin 2, conserved barrel domain protein F9800_30025 ENOG4107YZX Universal stress protein F9800_30070 ENOG4108JYZ YitT family F9800_30090 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) F9800_30100 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) F9800_30105 ENOG4105KBJ sporulation protein ytfj F9800_30120 ENOG4105EFZ amidohydrolase F9800_30130 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) F9800_30155 ENOG4107RSM transcriptional regulator F9800_30165 ENOG4105U5Y Transcriptional regulator F9800_30175 ENOG4105C28 cystathionine F9800_30200 ENOG4108UW5 maltose o-acetyltransferase F9800_30210 ENOG4105F1V Acetoin utilization protein F9800_30215 ENOG4105W87 Cbs domain F9800_30220 ENOG4105DGU Histone deacetylase F9800_30235 ENOG4105DPZ Two component transcriptional regulator (Winged helix family F9800_30240 ENOG4105BZU Histidine kinase F9800_30245 ENOG4107SNB ankyrin repeat protein YahD F9800_30250 ENOG4105EP9 oxidoreductase F9800_30280 ENOG4105ETE Transcriptional regulator (LacI family F9800_30290 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase F9800_30295 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase F9800_30315 ENOG4105C88 aminopeptidase F9800_30335 ENOG4108IPJ Membrane F9800_30370 ENOG4108VDD TRNA binding domain protein F9800_30400 ENOG4105C8F Beta-lactamase domain protein F9800_30415 ENOG4108V15 phosphotransferase enzyme family F9800_30420 ENOG4108IUM Glycogen debranching enzyme F9800_30430 ENOG4107QSE Dipeptidase F9800_30435 ENOG4105YW5 deoR family transcriptional regulator F9800_30450 ENOG4105CBX hi0933 family F9800_30485 ENOG4108VJ1 Transcriptional regulator (CarD family F9800_30490 ENOG4107EXU Short-chain dehydrogenase reductase Sdr F9800_30495 ENOG4105CSC Glucose uptake protein F9800_30510 ENOG4108ZAF Molybdopterin F9800_30515 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein F9800_30520 ENOG4105CVM Molybdenum cofactor synthesis domain protein F9800_30530 ENOG4105D06 uba thif-type nad fad binding protein F9800_30535 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) F9800_30555 ENOG41085GJ domain protein F9800_30565 ENOG4105DWV Homoserine O-trans-acetylase F9800_30605 ENOG410605W Major Facilitator F9800_30610 ENOG4107S91 Sodium hydrogen exchanger F9800_30615 ENOG4105NCW Trka-c domain protein F9800_30630 ENOG4105C19 ABC transporter F9800_30650 ENOG4105N5T Radical SAM Protein F9800_30680 ENOG4105E8V Alpha Beta Hydrolase Fold protein F9800_30685 ENOG4108Z0R Transferase F9800_30690 ENOG4105YVM Phosphoesterase, PA-phosphatase related F9800_30695 ENOG4105BZF Glycosyl transferase (Group 1 F9800_30705 ENOG4105EPU Molybdenum cofactor synthesis domain protein F9800_30790 ENOG4105BZU Histidine kinase F9800_30795 ENOG4105BZU Histidine kinase F9800_30800 ENOG4105CH6 catalase F9800_30805 ENOG4107S9D Alpha beta hydrolase F9800_30810 ENOG4107T7U Sulfatase F9800_30835 ENOG4105D2X ABC transporter substrate-binding protein F9800_30845 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component F9800_30905 ENOG41080TC multidrug resistance protein F9800_30910 ENOG410839T multidrug resistance protein F9800_30930 ENOG4108V2W Carbonate dehydratase F9800_30935 ENOG4105C4M (Ubiquinol oxidase) subunit I F9800_30940 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii F9800_30985 ENOG41087YS Phage shock protein A F9800_31010 ENOG4105N67 Proton-coupled thiamine transporter YuaJ F9800_31015 ENOG4105BZU Histidine kinase F9800_31020 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_31045 ENOG4108UGV hypoxanthine phosphoribosyltransferase F9800_31050 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) F9800_31105 ENOG4105BZU Histidine kinase F9800_31115 ENOG4107ZTW SNARE associated Golgi F9800_31130 ENOG4105C19 ABC transporter F9800_31135 ENOG41086D8 Transcriptional regulator F9800_31145 ENOG4105CJ1 ABC, transporter F9800_31155 ENOG41082BM Transcriptional regulator, arsr family F9800_31200 ENOG4105C6Z Gluconate F9800_31205 ENOG4105FDP GntR family transcriptional regulator F9800_31225 ENOG41069H0 dihydroorotase EC 3.5.2.3 F9800_31250 ENOG4105DTQ mandelate racemase muconate lactonizing F9800_31260 ENOG4108IPT Naphthoate synthase F9800_31265 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) F9800_31275 ENOG4105E4F Isochorismate synthase F9800_31280 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase F9800_31290 ENOG4105VEQ Cold shock protein F9800_31325 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) F9800_31350 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) F9800_31355 ENOG4108Q5F Tetr family transcriptional regulator F9800_31500 ENOG4105KT7 mgtC SapB transporter F9800_31505 ENOG4107PBV potassium channel F9800_31525 ENOG4105WG9 Conserved Protein F9800_31535 ENOG4105CHM Aminotransferase F9800_31540 ENOG4108ZB6 transcriptional regulator AsnC family F9800_31545 ENOG4105C5I Dehydrogenase F9800_31550 ENOG4108MUZ hydrolase F9800_31560 ENOG4105C87 Aminotransferase class I and II F9800_31570 ENOG4105Y38 Kinase-associated protein B F9800_31580 ENOG4107R3E Citrate transporter F9800_31595 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) F9800_31600 ENOG4105KA0 thioesterase Superfamily protein F9800_31615 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase F9800_31635 ENOG41069ER domain protein F9800_31650 ENOG4105CEP NADH dehydrogenase F9800_31675 ENOG4105EWC Purine nucleoside phosphorylase F9800_31710 ENOG4108YX9 iron--sulfur cluster insertion protein erpA F9800_31735 ENOG4108JJA ABC, transporter F9800_31740 ENOG4105C4B ABC transporter, permease F9800_31745 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA F9800_31790 ENOG41083MR nifu domain-containing protein F9800_31810 ENOG4108W5N phosphatidylglycerophosphatase a F9800_31830 ENOG4105DAX Pfam:DUF2983 F9800_31840 ENOG4105DYS nad(p)h dehydrogenase (quinone) F9800_31845 ENOG4105D4U had-superfamily hydrolase, subfamily iia F9800_31860 ENOG4105CBT Fructose-1,6-bisphosphatase F9800_31880 ENOG4105MMD transcriptional regulator F9800_31885 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) F9800_31890 ENOG4107TXC Transcriptional regulator F9800_31895 ENOG41090T1 Membrane F9800_31920 ENOG4105FAA peptidase M23 F9800_31925 ENOG4108YTE sporulation protein YunB F9800_31930 ENOG4105KZD Domain of unknown function (DUF1805) F9800_31935 ENOG4107R8B 5'-nucleotidase F9800_31940 ENOG4105DIW FeS assembly protein SUFB F9800_31945 ENOG4108UNV SUF system FeS assembly protein, NifU family F9800_31950 ENOG4105C9B Cysteine desulfurase F9800_31955 ENOG4105JRK feS assembly protein SufD F9800_31960 ENOG4105C3K feS assembly ATPase SufC F9800_31965 ENOG4105D01 (LipO)protein F9800_31970 ENOG4105D01 (LipO)protein F9800_31975 ENOG4108UMI ABC transporter, permease F9800_31980 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) F9800_32005 ENOG41080E8 Transcriptional regulator, Spx MgsR family F9800_32025 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) F9800_32040 ENOG4108W8B Beta-lactamase domain protein F9800_32045 ENOG4105C1G acyl-Coa dehydrogenase F9800_32050 ENOG4105CHU acetyl-coa acetyltransferase F9800_32065 ENOG4105DZ1 carboxypeptidase F9800_32085 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer F9800_32100 ENOG4108SUT Major Facilitator Superfamily F9800_32105 ENOG4107R7I amino acid F9800_32120 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins F9800_32130 ENOG4107AYK membrAne F9800_32175 ENOG4107ZTW SNARE associated Golgi F9800_32185 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein F9800_32190 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_32195 ENOG4105BZU Histidine kinase F9800_32220 ENOG4105C8Q Methyl-accepting chemotaxis F9800_32225 ENOG4105C8Q Methyl-accepting chemotaxis F9800_32230 ENOG4105VG1 fes assembly suf system protein F9800_32240 ENOG4105D4Y metalloprotease F9800_32245 ENOG4105C2I pirin domain protein F9800_32260 ENOG4107T5V SNARE associated Golgi F9800_32265 ENOG4107S91 Sodium hydrogen exchanger F9800_32270 ENOG4105NCW Trka-c domain protein F9800_32280 ENOG4108RMU ferritin dps family protein F9800_32295 ENOG4108URH decarboxylase F9800_32305 ENOG41090A1 ferritin F9800_32315 ENOG4105D9N nucleoside F9800_32325 ENOG4105D9N nucleoside F9800_32340 ENOG4108RYK Nad-dependent epimerase dehydratase F9800_32355 ENOG4105CV8 reductase F9800_32360 ENOG4105F27 Major Facilitator F9800_32365 ENOG4105KVH Transcriptional regulator F9800_32385 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) F9800_32390 ENOG4105D4A Cell wall formation (By similarity) F9800_32400 ENOG4105C8Q Methyl-accepting chemotaxis F9800_32415 ENOG4105WMR Protein CrcB homolog F9800_32435 ENOG4105C5H ABC transporter F9800_32440 ENOG4108MK9 spermidine N(1)-acetyltransferase F9800_32450 ENOG4108VY7 phosphate-starvation-inducible protein PsiE F9800_32460 ENOG4108W2Y isochorismatase F9800_32480 ENOG4108V2W Carbonate dehydratase F9800_32485 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) F9800_32500 ENOG4108IPW abc transporter atp-binding protein F9800_32505 ENOG4105CM4 permease protein F9800_32535 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) F9800_32545 ENOG4105XZU Preprotein translocase, subunit SecG F9800_32550 ENOG41067MG lrgb family F9800_32600 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_32620 ENOG41090VF Stage v sporulation protein ac F9800_32625 ENOG4105CZ3 stage V sporulation protein ad F9800_32640 ENOG4108QY0 Membrane F9800_32645 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) F9800_32650 ENOG4105KRI phosphocarrier protein (HPr F9800_32660 ENOG4105CHW UPF0052 protein F9800_32670 ENOG4108Z4K mutator MutT protein F9800_32680 ENOG4105C3M thioredoxin reductase F9800_32690 ENOG4108S4C acetyltransferase F9800_32710 ENOG41086DT Membrane protein of unknown function F9800_32720 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) F9800_32740 ENOG4107TXC Transcriptional regulator F9800_32755 ENOG4105HMI Membrane F9800_32760 ENOG4105DUM transcriptional regulator, lysR family F9800_32770 ENOG4108WS4 fmn reductase F9800_32775 ENOG4105C5H ABC transporter F9800_32785 ENOG4105BZ1 (ABC) transporter F9800_32795 ENOG4105CN1 protease F9800_32800 ENOG4105CRP Part of the ABC transporter FtsEX involved in F9800_32805 ENOG4105CAK Cell division ATP-binding protein ftsE F9800_32825 ENOG4105MS2 ribosomal subunit Interface protein F9800_32830 ENOG4105VEQ Cold shock protein F9800_32835 ENOG41081UC Inherit from COG: Competence protein F9800_32850 ENOG4105KVH Transcriptional regulator F9800_32860 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein F9800_32865 ENOG4108KGH TRANSCRIPTIONal F9800_32870 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase F9800_32875 ENOG4105C6Y Udp-glucose 6-dehydrogenase F9800_32880 ENOG4105ESV Glycosyl transferase, family 4 F9800_32890 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family F9800_32915 ENOG4105F8D glycoside hydrolase family 4 F9800_32920 ENOG4105VCP PTS System F9800_32925 ENOG4105CK1 PTS System F9800_32935 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) F9800_32940 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) F9800_32945 ENOG4105VCP PTS System F9800_32955 ENOG4105VZJ PTS System F9800_32980 ENOG4105ECB domain protein F9800_32985 ENOG4107RSM transcriptional regulator F9800_33015 ENOG4105DAA L-lactate F9800_33025 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) F9800_33040 ENOG4105E0M Sulfatase F9800_33065 ENOG4107R8N Glycosyl transferase, family 2 F9800_33070 ENOG4105C94 Transporter F9800_33080 ENOG41069ER domain protein F9800_33105 ENOG4105KBK Zinc finger, swim domain protein F9800_33110 ENOG4105C0D helicase F9800_33140 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) F9800_33150 ENOG4107RBB ABC transporter, permease F9800_33155 ENOG4105C19 ABC transporter F9800_33175 ENOG4105CXY transporter F9800_33190 ENOG4105BZU Histidine kinase F9800_33195 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_33205 ENOG4108KGH TRANSCRIPTIONal F9800_33210 ENOG4105CMR udp-glucose 4-epimerase F9800_33215 ENOG4105C6Y Udp-glucose 6-dehydrogenase F9800_33225 ENOG4105CPK Glycosyl transferase (Group 1 F9800_33240 ENOG4105D3Q Sugar transferase F9800_33245 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase F9800_33250 ENOG4108RB3 Capsular polysaccharide biosynthesis protein F9800_33255 ENOG4107YJ4 chain length determinant protein F9800_33260 ENOG4105HTX biosynthesis protein F9800_33265 ENOG4107YJ4 chain length determinant protein F9800_33280 ENOG4105MT0 Sporulation transcriptional regulator spoiiid F9800_33290 ENOG4105FRN stage II sporulation protein F9800_33305 ENOG4105DY9 regulatoR F9800_33325 ENOG4106778 Protein of unknown function (DUF1146) F9800_33330 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) F9800_33335 ENOG4105C8S subunit m F9800_33340 ENOG4105D65 subunit l F9800_33365 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) F9800_33370 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain F9800_33380 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain F9800_33385 ENOG4105BZU Histidine kinase F9800_33435 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) F9800_33440 ENOG41062M3 atp synthase F9800_33465 ENOG4108UIC UPF0340 protein F9800_33470 ENOG4108YZG isomerase F9800_33485 ENOG4108VGI doxx family F9800_33490 ENOG4107XC4 flavin reductase domain protein, FMN-binding F9800_33515 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) F9800_33525 ENOG4108ZXQ stage ii sporulation protein r F9800_33530 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) F9800_33535 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) F9800_33550 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) F9800_33555 ENOG4105CBT Fructose-1,6-bisphosphatase F9800_33560 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) F9800_33600 ENOG4105C1G acyl-Coa dehydrogenase F9800_33605 ENOG4105C1G acyl-Coa dehydrogenase F9800_33610 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase F9800_33620 ENOG4105DF6 Fe-S oxidoreductase F9800_33625 ENOG41067QW Transcriptional regulator F9800_33665 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin F9800_33670 ENOG4105KVY Required for disulfide bond formation in some proteins (By similarity) F9800_33725 ENOG4105BZU Histidine kinase F9800_33740 ENOG4105D4Y metalloprotease F9800_33750 ENOG4105BZU Histidine kinase F9800_33755 ENOG4105KCT ABC transporter F9800_33760 ENOG4108M15 ABC transporter F9800_33765 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) F9800_33775 ENOG4105IIU Aminopeptidase F9800_33795 ENOG4105EMN RNA polymerase sigma factor F9800_33805 ENOG410684U Domain of unknown function (DUF1934) F9800_33825 ENOG4105CYW agmatinase F9800_33835 ENOG4105DXB Major Facilitator superfamily F9800_33840 ENOG4107SWG transcriptional regulator MERR family F9800_33845 ENOG4108QXE glycerophosphoryl diester phosphodiesterase F9800_33850 ENOG4105BZ4 penicillin-binding protein F9800_33855 ENOG4108XFG YwhD family F9800_33860 ENOG4108Z4T Peptidase M50 F9800_33865 ENOG41069HH 4-oxalocrotonate tautomerase F9800_33870 ENOG4105DCI Phosphohydrolase F9800_33875 ENOG4108MES Periplasmic binding protein F9800_33880 ENOG4105E0A ABC, transporter F9800_33885 ENOG4105EHG Permease protein F9800_33890 ENOG4105DQ5 transport system permease protein F9800_33900 ENOG4108VCI transcription factor, rsfa family F9800_33905 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) F9800_33910 ENOG4108IJ2 phosphate acetyltransferase F9800_33915 ENOG4107UEZ chlorite dismutase F9800_33930 ENOG4108VKI Cell wall hydrolase F9800_33950 ENOG4107SVH Potassium channel protein F9800_33960 ENOG410667J hydrolase F9800_33965 ENOG4105VCH membrane F9800_33975 ENOG4108TU7 Inherit from COG: (ABC) transporter F9800_33980 ENOG4105CJ1 ABC, transporter F9800_33985 ENOG41090WU lipolytic protein G-D-S-L family F9800_34000 ENOG4105D6E homoserine dehydrogenase F9800_34020 ENOG4108Y4K DNA-binding transcriptional activator F9800_34030 ENOG4105WH1 Two component transcriptional regulator luxr family F9800_34035 ENOG4105BZU Histidine kinase F9800_34040 ENOG4105DWF phosphomethylpyrimidine kinase F9800_34045 ENOG4105BZU Histidine kinase F9800_34055 ENOG4105VCD cytoplasmic protein F9800_34060 ENOG4105D22 carbon starvation protein F9800_34065 ENOG4105DY9 regulatoR F9800_34070 ENOG41079KZ Major Facilitator Superfamily F9800_34085 ENOG4105CG5 Glycosyl transferase (Group 1 F9800_34095 ENOG4105EN6 Membrane F9800_34100 ENOG4106YBV Methyl-accepting chemotaxis F9800_34110 ENOG4108S4H thioesterase Superfamily protein F9800_34115 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) F9800_34130 ENOG4105K64 Glycosyl transferase, family 2 F9800_34140 ENOG4105EJV Membrane F9800_34145 ENOG4105CKK Glycosyl transferase, family 2 F9800_34155 ENOG4108IG5 Transcriptional regulator F9800_34160 ENOG4105C5H ABC transporter F9800_34165 ENOG41067SE Tetr family transcriptional regulator F9800_34175 ENOG4105E0X reductase F9800_34180 ENOG4106F5Q Membrane F9800_34195 ENOG4108NEV two component transcriptional regulator, LytTR family F9800_34200 ENOG4108HRK Histidine kinase F9800_34205 ENOG4107RGD Major Facilitator superfamily F9800_34225 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) F9800_34235 ENOG4105IW1 AmiS UreI transporter F9800_34250 ENOG4105CMR udp-glucose 4-epimerase F9800_34255 ENOG4108UT2 hemolysin iii F9800_34265 ENOG4105C1J atp-dependent rna helicase F9800_34270 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) F9800_34275 ENOG4105DPN Oligoendopeptidase f F9800_34295 ENOG4107Y5K Resolvase F9800_34340 ENOG4107Y5K Resolvase F9800_34345 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) F9800_34390 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) F9800_34405 ENOG4105C0H protease F9800_34410 ENOG4105Q2H domain protein F9800_34425 ENOG4105BZU Histidine kinase F9800_34430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family F9800_34455 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis F9800_34460 ENOG4105CDU Replicative dna helicase F9800_34470 ENOG4105BZR domain protein F9800_34475 ENOG4108XMW Membrane F9800_34485 ENOG4108UUM single-stranded DNA-binding protein F9800_34495 ENOG4105C3G gtp-binding protein F9800_34500 ENOG4105VDK protein, conserved in bacteria F9800_34505 ENOG4105D8X mechanosensitive ion channel F9800_34510 ENOG4108ZDA Sporulation protein YyaC F9800_34515 ENOG4105FA0 parb-like partition protein F9800_34520 ENOG4107QJE Chromosome Partitioning Protein F9800_34540 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) F9800_34550 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins