locus-tag	class	description
K8Z23_00005	COG1802	Transcriptional regulator
K8Z23_00005	COG4626	Terminase
K8Z23_00015	COG0740	serine-type endopeptidase activity
K8Z23_00080	COG4824	toxin secretion phage lysis holin
K8Z23_00085	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z23_00085	COG3409	Peptidoglycan-binding domain 1 protein
K8Z23_00085	COG1388	LysM domain
K8Z23_00105	COG1674	ftsk spoiiie
K8Z23_00120	COG0557	exoribonuclease II activity
K8Z23_00165	COG2233	PERMEase
K8Z23_00170	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z23_00175	COG0288	reversible hydration of carbon dioxide
K8Z23_00180	COG1522	sequence-specific DNA binding
K8Z23_00190	COG1522	sequence-specific DNA binding
K8Z23_00195	COG1335	isochorismatase
K8Z23_00215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_00220	COG0488	(ABC) transporter
K8Z23_00255	COG3290	protein histidine kinase activity
K8Z23_00255	COG0840	transmembrane signaling receptor activity
K8Z23_00275	COG1252	NADH dehydrogenase
K8Z23_00285	COG1733	regulation of RNA biosynthetic process
K8Z23_00290	COG2814	Major facilitator Superfamily
K8Z23_00295	COG0656	L-ascorbic acid biosynthetic process
K8Z23_00310	COG2910	NAD(P)H-binding
K8Z23_00315	COG1115	amino acid carrier protein
K8Z23_00320	COG1115	amino acid carrier protein
K8Z23_00325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z23_00330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z23_00335	COG2311	Membrane
K8Z23_00350	COG1611	Belongs to the LOG family
K8Z23_00370	COG0783	Belongs to the Dps family
K8Z23_00375	COG1115	amino acid carrier protein
K8Z23_00380	COG0490	domain, Protein
K8Z23_00385	COG0475	glutathione-regulated potassium exporter activity
K8Z23_00390	COG0586	Pfam SNARE associated Golgi protein
K8Z23_00410	COG3227	Zinc metalloprotease (Elastase)
K8Z23_00415	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z23_00420	COG0840	transmembrane signaling receptor activity
K8Z23_00450	COG5002	protein histidine kinase activity
K8Z23_00455	COG0745	RESPONSE REGULATOR receiver
K8Z23_00460	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z23_00470	COG0586	Pfam SNARE associated Golgi protein
K8Z23_00510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_00535	COG0531	amino acid
K8Z23_00540	COG2814	Major facilitator Superfamily
K8Z23_00555	COG0840	transmembrane signaling receptor activity
K8Z23_00560	COG0011	TIGRFAM Protein of
K8Z23_00575	COG1686	Belongs to the peptidase S11 family
K8Z23_00585	COG1024	Enoyl-CoA hydratase
K8Z23_00585	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z23_00590	COG0183	Belongs to the thiolase family
K8Z23_00595	COG1960	acyl-CoA dehydrogenase activity
K8Z23_00600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_00615	COG0039	L-malate dehydrogenase activity
K8Z23_00635	COG1393	Belongs to the ArsC family
K8Z23_00645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z23_00650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z23_00665	COG2011	ABC-type metal ion transport system permease component
K8Z23_00670	COG1464	Belongs to the NlpA lipoprotein family
K8Z23_00675	COG1464	Belongs to the NlpA lipoprotein family
K8Z23_00680	COG0396	ATPase activity
K8Z23_00685	COG0719	Fe-S assembly protein
K8Z23_00690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z23_00695	COG0822	iron-sulfur transferase activity
K8Z23_00700	COG0719	Fe-S assembly protein
K8Z23_00705	COG0737	Belongs to the 5'-nucleotidase family
K8Z23_00710	COG3377	Domain of unknown function (DUF1805)
K8Z23_00720	COG0739	heme binding
K8Z23_00745	COG4377	Putative membrane peptidase family (DUF2324)
K8Z23_00750	COG0789	Transcriptional regulator
K8Z23_00760	COG4470	Protein conserved in bacteria
K8Z23_00775	COG1494	fructose-1,6-bisphosphatase
K8Z23_00780	COG2445	Protein of unknown function DUF86
K8Z23_00790	COG0647	UMP catabolic process
K8Z23_00795	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z23_00810	COG1358	cellular component organization or biogenesis
K8Z23_00830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z23_00835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z23_00845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z23_00850	COG4837	Protein of unknown function (DUF1462)
K8Z23_00875	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z23_00880	COG0390	transport system, permease component
K8Z23_00885	COG2274	protein secretion by the type I secretion system
K8Z23_00895	COG1252	NADH dehydrogenase
K8Z23_00910	COG0316	Belongs to the HesB IscA family
K8Z23_00940	COG1683	Conserved Protein
K8Z23_00955	COG3708	Transcriptional regulator
K8Z23_00970	COG1252	NADH dehydrogenase
K8Z23_00985	COG3584	3D domain protein
K8Z23_01000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z23_01005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z23_01010	COG1268	BioY protein
K8Z23_01020	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z23_01040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z23_01045	COG5018	Exonuclease
K8Z23_01070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z23_01080	COG2267	carboxylic ester hydrolase activity
K8Z23_01085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z23_01090	COG1522	sequence-specific DNA binding
K8Z23_01095	COG0436	Aminotransferase
K8Z23_01100	COG1098	S1 RNA binding domain
K8Z23_01105	COG2155	Conserved Protein
K8Z23_01120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z23_01125	COG1285	pathogenesis
K8Z23_01260	COG1309	transcriptional regulator
K8Z23_01285	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z23_01290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z23_01300	COG0058	SHG alpha-glucan phosphorylase activity
K8Z23_01325	COG1278	Cold shock
K8Z23_01330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z23_01335	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z23_01340	COG1169	isochorismate synthase
K8Z23_01350	COG0596	Alpha beta hydrolase
K8Z23_01355	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z23_01365	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z23_01385	COG3964	amidohydrolase
K8Z23_01405	COG2188	Transcriptional regulator
K8Z23_01420	COG0577	efflux transmembrane transporter activity
K8Z23_01425	COG1136	(ABC) transporter
K8Z23_01430	COG0577	efflux transmembrane transporter activity
K8Z23_01435	COG0577	efflux transmembrane transporter activity
K8Z23_01440	COG2205	protein histidine kinase activity
K8Z23_01445	COG0745	RESPONSE REGULATOR receiver
K8Z23_01455	COG0640	Transcriptional regulator
K8Z23_01460	COG5658	integral membrane protein
K8Z23_01465	COG1131	(ABC) transporter
K8Z23_01475	COG3708	Transcriptional regulator
K8Z23_01475	COG2207	Transcriptional regulator
K8Z23_01480	COG1136	(ABC) transporter
K8Z23_01485	COG0577	efflux transmembrane transporter activity
K8Z23_01495	COG0586	Pfam SNARE associated Golgi protein
K8Z23_01545	COG1597	lipid kinase activity
K8Z23_01550	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z23_01575	COG0745	RESPONSE REGULATOR receiver
K8Z23_01580	COG5002	protein histidine kinase activity
K8Z23_01585	COG3859	Proton-coupled thiamine transporter YuaJ
K8Z23_01610	COG1842	Phage shock protein A
K8Z23_01635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_01655	COG1294	oxidase, subunit
K8Z23_01660	COG1271	oxidase subunit
K8Z23_01665	COG0288	reversible hydration of carbon dioxide
K8Z23_01675	COG1854	S-ribosylhomocysteine lyase activity
K8Z23_01680	COG0789	Transcriptional regulator
K8Z23_01685	COG2076	Multidrug Resistance protein
K8Z23_01690	COG2076	Multidrug Resistance protein
K8Z23_01720	COG0494	nUDIX hydrolase
K8Z23_01745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z23_01750	COG1116	anion transmembrane transporter activity
K8Z23_01755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z23_01770	COG1368	sulfuric ester hydrolase activity
K8Z23_01775	COG2267	carboxylic ester hydrolase activity
K8Z23_01795	COG3852	Histidine kinase
K8Z23_01800	COG5002	protein histidine kinase activity
K8Z23_01895	COG0438	transferase activity, transferring glycosyl groups
K8Z23_01900	COG0671	phosphoesterase, PA-phosphatase related
K8Z23_01905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z23_01910	COG2267	carboxylic ester hydrolase activity
K8Z23_01925	COG1794	racemase activity, acting on amino acids and derivatives
K8Z23_01930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z23_01935	COG1242	4 iron, 4 sulfur cluster binding
K8Z23_01955	COG1136	(ABC) transporter
K8Z23_01965	COG0582	viral genome integration into host DNA
K8Z23_01970	COG0490	domain, Protein
K8Z23_01975	COG0475	glutathione-regulated potassium exporter activity
K8Z23_01980	COG2814	Major facilitator Superfamily
K8Z23_02020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z23_02030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z23_02050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z23_02055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z23_02065	COG0303	'Molybdopterin
K8Z23_02070	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z23_02075	COG0314	molybdopterin synthase activity
K8Z23_02100	COG1329	Transcriptional regulator
K8Z23_02120	COG3832	glyoxalase III activity
K8Z23_02130	COG2814	Major facilitator Superfamily
K8Z23_02135	COG2081	HI0933 family
K8Z23_02140	COG2244	polysaccharide biosynthetic process
K8Z23_02145	COG1187	pseudouridine synthase activity
K8Z23_02150	COG1349	DNA-binding transcription factor activity
K8Z23_02155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z23_02165	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z23_02170	COG0510	thiamine kinase activity
K8Z23_02185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_02195	COG1363	Peptidase, m42
K8Z23_02200	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z23_02205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z23_02215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z23_02230	COG1674	ftsk spoiiie
K8Z23_02245	COG0789	Transcriptional regulator
K8Z23_02250	COG0697	spore germination
K8Z23_02255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_02280	COG3118	belongs to the thioredoxin family
K8Z23_02285	COG4851	CamS sex pheromone cAM373 precursor
K8Z23_02290	COG1605	Chorismate mutase
K8Z23_02290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z23_02295	COG1605	Chorismate mutase
K8Z23_02295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z23_02305	COG1609	Transcriptional regulator
K8Z23_02340	COG0666	response to abiotic stimulus
K8Z23_02345	COG5002	protein histidine kinase activity
K8Z23_02350	COG0745	RESPONSE REGULATOR receiver
K8Z23_02365	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z23_02370	COG0517	IMP dehydrogenase activity
K8Z23_02375	COG0454	-acetyltransferase
K8Z23_02380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z23_02385	COG0110	maltose O-acetyltransferase activity
K8Z23_02420	COG0626	cystathionine gamma-synthase activity
K8Z23_02425	COG1956	GAF domain-containing protein
K8Z23_02430	COG1309	transcriptional regulator
K8Z23_02435	COG0697	spore germination
K8Z23_02440	COG0583	DNA-binding transcription factor activity
K8Z23_02450	COG1104	cysteine desulfurase activity
K8Z23_02465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z23_02475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z23_02490	COG3874	Sporulation protein YtfJ
K8Z23_02495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z23_02500	COG0827	DNA restriction-modification system
K8Z23_02525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_02570	COG0589	response to stress
K8Z23_02575	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_02590	COG0662	Cupin 2, conserved barrel domain protein
K8Z23_02595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_02635	COG0006	proline dipeptidase activity
K8Z23_02650	COG4109	DRTGG domain
K8Z23_02665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z23_02680	COG0587	DNA-directed DNA polymerase activity
K8Z23_02685	COG0281	malic enzyme
K8Z23_02690	COG1725	Transcriptional regulator
K8Z23_02715	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z23_02720	COG0628	permease
K8Z23_02730	COG0372	Belongs to the citrate synthase family
K8Z23_02735	COG0538	isocitrate dehydrogenase activity
K8Z23_02755	COG0745	RESPONSE REGULATOR receiver
K8Z23_02760	COG5002	protein histidine kinase activity
K8Z23_02765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z23_02765	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z23_02775	COG1971	Probably functions as a manganese efflux pump
K8Z23_02780	COG0237	dephospho-CoA kinase activity
K8Z23_02785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z23_02790	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z23_02800	COG3611	Membrane attachment protein
K8Z23_02805	COG1484	DNA-dependent DNA replication
K8Z23_02820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z23_02845	COG1363	Peptidase, m42
K8Z23_02850	COG1309	transcriptional regulator
K8Z23_02855	COG1566	PFAM secretion protein HlyD family protein
K8Z23_02860	COG2814	Major facilitator Superfamily
K8Z23_02875	COG1418	mRNA catabolic process
K8Z23_02885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z23_02925	COG1286	toxin biosynthetic process
K8Z23_02930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z23_02930	COG1796	DNA polymerase
K8Z23_02940	COG1187	pseudouridine synthase activity
K8Z23_02945	COG1114	Component of the transport system for branched-chain amino acids
K8Z23_02950	COG5386	Cell surface protein
K8Z23_02960	COG5386	Cell surface protein
K8Z23_02975	COG1120	ATPase activity
K8Z23_02980	COG4509	Sortase family
K8Z23_02990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z23_02995	COG4895	conserved protein (DUF2196)
K8Z23_03005	COG0745	RESPONSE REGULATOR receiver
K8Z23_03010	COG2205	protein histidine kinase activity
K8Z23_03015	COG1131	(ABC) transporter
K8Z23_03035	COG2318	DinB family
K8Z23_03060	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z23_03065	COG1309	transcriptional regulator
K8Z23_03070	COG1024	Enoyl-CoA hydratase
K8Z23_03075	COG2086	electron transfer activity
K8Z23_03080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z23_03085	COG3118	belongs to the thioredoxin family
K8Z23_03095	COG1719	4-vinyl reductase, 4VR
K8Z23_03100	COG2009	succinate dehydrogenase
K8Z23_03105	COG1053	succinate dehydrogenase
K8Z23_03110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z23_03115	COG0824	Thioesterase
K8Z23_03120	COG1876	peptidase activity
K8Z23_03125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z23_03130	COG1360	Flagellar Motor Protein
K8Z23_03135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z23_03140	COG4152	abc transporter atp-binding protein
K8Z23_03145	COG1668	transmembrane transport
K8Z23_03150	COG1959	2 iron, 2 sulfur cluster binding
K8Z23_03160	COG0697	spore germination
K8Z23_03165	COG1396	sequence-specific DNA binding
K8Z23_03170	COG1983	PspC domain protein
K8Z23_03175	COG0402	S-adenosylhomocysteine deaminase activity
K8Z23_03180	COG2233	PERMEase
K8Z23_03185	COG2197	response regulator
K8Z23_03195	COG1396	sequence-specific DNA binding
K8Z23_03195	COG3800	Transcriptional regulator
K8Z23_03335	COG1802	Transcriptional regulator
K8Z23_03335	COG4626	Terminase
K8Z23_03415	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z23_03475	COG2197	response regulator
K8Z23_03485	COG1309	transcriptional regulator
K8Z23_03505	COG5401	PFAM Sporulation and spore germination
K8Z23_03520	COG0622	Phosphoesterase
K8Z23_03565	COG0470	DNA polymerase III
K8Z23_03565	COG1067	ATP-dependent peptidase activity
K8Z23_03580	COG1764	response to oxidative stress
K8Z23_03585	COG1846	Transcriptional regulator
K8Z23_03595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z23_03605	COG1587	Uroporphyrinogen-III synthase
K8Z23_03610	COG0113	porphobilinogen synthase activity
K8Z23_03620	COG1388	LysM domain
K8Z23_03635	COG0285	dihydrofolate synthase activity
K8Z23_03655	COG1077	Cell shape determining protein MreB Mrl
K8Z23_03675	COG2894	cell division
K8Z23_03680	COG0739	heme binding
K8Z23_03685	COG1994	Peptidase M50
K8Z23_03690	COG1530	ribonuclease E activity
K8Z23_03700	COG2868	ribosomal protein
K8Z23_03710	COG3290	protein histidine kinase activity
K8Z23_03720	COG0745	RESPONSE REGULATOR receiver
K8Z23_03725	COG5002	protein histidine kinase activity
K8Z23_03730	COG1136	(ABC) transporter
K8Z23_03735	COG0577	efflux transmembrane transporter activity
K8Z23_03740	COG0577	efflux transmembrane transporter activity
K8Z23_03745	COG0077	Prephenate dehydratase
K8Z23_03755	COG2258	MOSC domain
K8Z23_03760	COG1827	regulation of RNA biosynthetic process
K8Z23_03765	COG1104	cysteine desulfurase activity
K8Z23_03770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z23_03775	COG0157	Belongs to the NadC ModD family
K8Z23_03810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z23_03840	COG1862	Preprotein translocase
K8Z23_03850	COG2323	membrane
K8Z23_03855	COG2244	polysaccharide biosynthetic process
K8Z23_03865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z23_03865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z23_03870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z23_03875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z23_03875	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z23_03885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z23_03915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z23_03925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z23_03930	COG1959	2 iron, 2 sulfur cluster binding
K8Z23_03935	COG1104	cysteine desulfurase activity
K8Z23_03950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z23_03970	COG0628	permease
K8Z23_03985	COG4472	Bacterial protein of unknown function (DUF965)
K8Z23_04000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z23_04005	COG4122	O-methyltransferase activity
K8Z23_04010	COG0826	peptidase U32
K8Z23_04015	COG0826	peptidase U32
K8Z23_04035	COG0768	penicillin binding
K8Z23_04060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z23_04065	COG0626	cystathionine gamma-synthase activity
K8Z23_04070	COG1012	belongs to the aldehyde dehydrogenase family
K8Z23_04070	COG1454	alcohol dehydrogenase
K8Z23_04080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_04120	COG2259	Doxx family
K8Z23_04125	COG2514	catechol 2,3-dioxygenase activity
K8Z23_04135	COG3186	Phenylalanine-4-hydroxylase
K8Z23_04140	COG1404	Belongs to the peptidase S8 family
K8Z23_04175	COG2267	carboxylic ester hydrolase activity
K8Z23_04185	COG1785	Belongs to the alkaline phosphatase family
K8Z23_04195	COG2357	RelA SpoT domain protein
K8Z23_04205	COG0778	Nitroreductase
K8Z23_04215	COG1595	DNA-templated transcription, initiation
K8Z23_04240	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z23_04245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z23_04255	COG1534	Rna-binding protein
K8Z23_04265	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z23_04270	COG0799	negative regulation of ribosome biogenesis
K8Z23_04275	COG2226	methyltransferase
K8Z23_04280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z23_04285	COG1555	photosystem II stabilization
K8Z23_04285	COG1596	polysaccharide export
K8Z23_04290	COG2131	deaminase
K8Z23_04295	COG0658	competence protein
K8Z23_04295	COG2333	competence protein COMEC
K8Z23_04305	COG1466	dna polymerase III delta subunit
K8Z23_04330	COG1733	regulation of RNA biosynthetic process
K8Z23_04335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z23_04365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z23_04370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z23_04375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z23_04380	COG1610	YqeY-like protein
K8Z23_04400	COG1702	phosphate starvation-inducible protein PhoH
K8Z23_04405	COG1480	7TM receptor with intracellular HD hydrolase
K8Z23_04415	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z23_04420	COG0295	cytidine deaminase activity
K8Z23_04425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z23_04440	COG0517	IMP dehydrogenase activity
K8Z23_04450	COG1671	Belongs to the UPF0178 family
K8Z23_04455	COG0358	DNA primase activity
K8Z23_04460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z23_04470	COG2384	SAM-dependent methyltransferase
K8Z23_04475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z23_04505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_04510	COG1121	(ABC) transporter
K8Z23_04515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z23_04520	COG0735	belongs to the Fur family
K8Z23_04535	COG5521	maltodextrose utilization protein MalA
K8Z23_04545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z23_04550	COG0477	Major facilitator Superfamily
K8Z23_04555	COG0768	penicillin binding
K8Z23_04565	COG0573	inorganic phosphate transmembrane transporter activity
K8Z23_04570	COG0573	inorganic phosphate transmembrane transporter activity
K8Z23_04580	COG0704	Plays a role in the regulation of phosphate uptake
K8Z23_04585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z23_04590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z23_04595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z23_04600	COG4483	Protein conserved in bacteria
K8Z23_04605	COG1940	carbohydrate kinase activity
K8Z23_04615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_04635	COG0626	cystathionine gamma-synthase activity
K8Z23_04640	COG0626	cystathionine gamma-synthase activity
K8Z23_04645	COG0646	methionine synthase
K8Z23_04645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z23_04705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z23_04710	COG1459	type II secretion system
K8Z23_04775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z23_04815	COG2076	Multidrug Resistance protein
K8Z23_04820	COG2076	Multidrug Resistance protein
K8Z23_04830	COG1609	Transcriptional regulator
K8Z23_04840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z23_04875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z23_04885	COG3872	metal-dependent enzyme
K8Z23_04900	COG0006	proline dipeptidase activity
K8Z23_04925	COG3854	ATPases associated with a variety of cellular activities
K8Z23_04970	COG0511	ligase activity, forming carbon-carbon bonds
K8Z23_04975	COG0439	Biotin carboxylase
K8Z23_04980	COG1302	Protein conserved in bacteria
K8Z23_05005	COG0142	geranyltranstransferase activity
K8Z23_05015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z23_05025	COG0497	DNA recombination
K8Z23_05030	COG0750	zinc metalloprotease
K8Z23_05045	COG3093	addiction module antidote protein HigA
K8Z23_05050	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z23_05060	COG3290	protein histidine kinase activity
K8Z23_05060	COG3829	transcription factor binding
K8Z23_05065	COG0280	phosphate acetyltransferase
K8Z23_05080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z23_05085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z23_05090	COG0022	dehydrogenase e1 component
K8Z23_05095	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z23_05100	COG0772	Belongs to the SEDS family
K8Z23_05105	COG2323	membrane
K8Z23_05125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z23_05130	COG0765	amino acid transport
K8Z23_05135	COG1126	abc transporter atp-binding protein
K8Z23_05140	COG4129	membrane
K8Z23_05145	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z23_05160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_05165	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z23_05175	COG1285	pathogenesis
K8Z23_05205	COG1760	l-serine dehydratase
K8Z23_05210	COG1760	l-serine dehydratase
K8Z23_05215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z23_05220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_05225	COG0300	oxidoreductase activity
K8Z23_05270	COG1522	sequence-specific DNA binding
K8Z23_05280	COG0737	Belongs to the 5'-nucleotidase family
K8Z23_05285	COG1757	Na H antiporter
K8Z23_05295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z23_05310	COG1073	alpha beta
K8Z23_05310	COG2226	methyltransferase
K8Z23_05340	COG0307	riboflavin synthase, alpha
K8Z23_05345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z23_05345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z23_05360	COG1073	alpha beta
K8Z23_05365	COG0456	acetyltransferase
K8Z23_05370	COG1609	Transcriptional regulator
K8Z23_05375	COG2056	Na+-H+ antiporter family
K8Z23_05380	COG0596	Alpha beta hydrolase
K8Z23_05390	COG0737	Belongs to the 5'-nucleotidase family
K8Z23_05390	COG1525	nuclease
K8Z23_05390	COG4085	toxin activity
K8Z23_05400	COG0456	acetyltransferase
K8Z23_05400	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z23_05405	COG0656	L-ascorbic acid biosynthetic process
K8Z23_05410	COG0667	Aldo Keto reductase
K8Z23_05430	COG1300	Membrane
K8Z23_05435	COG0735	belongs to the Fur family
K8Z23_05445	COG4974	Belongs to the 'phage' integrase family
K8Z23_05470	COG0598	Magnesium transport protein CorA
K8Z23_05485	COG1846	Transcriptional regulator
K8Z23_05510	COG1131	(ABC) transporter
K8Z23_05515	COG1725	Transcriptional regulator
K8Z23_05520	COG1686	Belongs to the peptidase S11 family
K8Z23_05540	COG0733	neurotransmitter:sodium symporter activity
K8Z23_05565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z23_05580	COG0697	spore germination
K8Z23_05585	COG0561	phosphatase activity
K8Z23_05590	COG4086	secreted protein
K8Z23_05595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z23_05600	COG0456	acetyltransferase
K8Z23_05605	COG1547	Domain of unknown function (DUF309)
K8Z23_05630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z23_05640	COG2188	Transcriptional regulator
K8Z23_05650	COG3711	transcriptional antiterminator
K8Z23_05655	COG2190	(PTS) system
K8Z23_05655	COG1263	PTS System
K8Z23_05655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z23_05680	COG0778	Nitroreductase
K8Z23_05685	COG2199	diguanylate cyclase activity
K8Z23_05695	COG2084	Dehydrogenase
K8Z23_05730	COG0436	Aminotransferase
K8Z23_05735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z23_05755	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_05760	COG1695	Transcriptional regulator
K8Z23_05790	COG0183	Belongs to the thiolase family
K8Z23_05830	COG3842	ATPase activity
K8Z23_05835	COG0366	Alpha amylase catalytic
K8Z23_05845	COG2182	Extracellular solute-binding protein
K8Z23_05850	COG1175	transmembrane transport
K8Z23_05855	COG3833	ABC-type maltose transport systems, permease component
K8Z23_05860	COG1609	Transcriptional regulator
K8Z23_05865	COG0436	Aminotransferase
K8Z23_05875	COG2205	protein histidine kinase activity
K8Z23_05885	COG3209	COG3209 Rhs family protein
K8Z23_05960	COG1408	metallophosphoesterase
K8Z23_05965	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_05970	COG2200	EAL domain
K8Z23_05985	COG4703	Protein of unknown function (DUF1797)
K8Z23_05995	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z23_06005	COG0517	IMP dehydrogenase activity
K8Z23_06010	COG0583	DNA-binding transcription factor activity
K8Z23_06030	COG0569	domain protein
K8Z23_06035	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z23_06045	COG0561	phosphatase activity
K8Z23_06060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z23_06065	COG0022	dehydrogenase e1 component
K8Z23_06115	COG1982	Orn Lys Arg decarboxylase major
K8Z23_06135	COG0483	inositol monophosphate 1-phosphatase activity
K8Z23_06145	COG1217	gtp-binding protein TYPA
K8Z23_06160	COG4896	Protein conserved in bacteria
K8Z23_06170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z23_06175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z23_06185	COG0772	Belongs to the SEDS family
K8Z23_06190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z23_06225	COG3336	cytochrome c oxidase
K8Z23_06240	COG2340	Cysteine-rich secretory protein family
K8Z23_06255	COG0406	alpha-ribazole phosphatase activity
K8Z23_06260	COG3679	Belongs to the UPF0342 family
K8Z23_06275	COG0742	ribosomal rna small subunit methyltransferase
K8Z23_06285	COG3314	Sporulation integral membrane protein YlbJ
K8Z23_06290	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z23_06295	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z23_06305	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z23_06310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z23_06325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z23_06345	COG0768	penicillin binding
K8Z23_06350	COG0768	penicillin binding
K8Z23_06370	COG0772	Belongs to the SEDS family
K8Z23_06390	COG0849	cell division
K8Z23_06395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z23_06405	COG1191	sigma factor activity
K8Z23_06410	COG1191	sigma factor activity
K8Z23_06415	COG1873	PFAM PRC-barrel domain
K8Z23_06425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z23_06435	COG0762	integral membrane protein
K8Z23_06440	COG2302	S4 RNA-binding domain
K8Z23_06445	COG3599	regulation of cell shape
K8Z23_06465	COG0564	pseudouridine synthase activity
K8Z23_06525	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z23_06555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z23_06560	COG1561	YicC-like family, N-terminal region
K8Z23_06580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z23_06585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z23_06600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z23_06600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z23_06610	COG0631	protein serine/threonine phosphatase activity
K8Z23_06615	COG0515	serine threonine protein kinase
K8Z23_06615	COG2815	serine threonine protein kinase
K8Z23_06625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z23_06630	COG1564	THIamine pyrophosphokinase
K8Z23_06645	COG1302	Protein conserved in bacteria
K8Z23_06650	COG1461	Dihydroxyacetone kinase
K8Z23_06655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z23_06670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z23_06675	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_06680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z23_06690	COG1196	nuclear chromosome segregation
K8Z23_06695	COG0552	protein localization to endoplasmic reticulum
K8Z23_06705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z23_06715	COG1837	Belongs to the UPF0109 family
K8Z23_06755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z23_06760	COG0758	DNA mediated transformation
K8Z23_06765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z23_06775	COG4974	Belongs to the 'phage' integrase family
K8Z23_06820	COG4589	Belongs to the CDS family
K8Z23_06830	COG0750	zinc metalloprotease
K8Z23_06850	COG0195	Participates in both transcription termination and antitermination
K8Z23_06855	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z23_06860	COG1358	cellular component organization or biogenesis
K8Z23_06870	COG1550	Protein conserved in bacteria
K8Z23_06875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z23_06885	COG0196	riboflavin kinase activity
K8Z23_06900	COG0726	polysaccharide deacetylase
K8Z23_06905	COG0612	Peptidase, M16
K8Z23_06910	COG1873	PFAM PRC-barrel domain
K8Z23_06915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z23_06940	COG1396	sequence-specific DNA binding
K8Z23_06975	COG0305	Participates in initiation and elongation during chromosome replication
K8Z23_07020	COG0582	viral genome integration into host DNA
K8Z23_07025	COG1278	Cold shock
K8Z23_07175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z23_07180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z23_07185	COG0527	aspartate kinase activity
K8Z23_07195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z23_07200	COG0740	serine-type endopeptidase activity
K8Z23_07215	COG2188	Transcriptional regulator
K8Z23_07220	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z23_07225	COG3845	ABC transporter
K8Z23_07230	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z23_07235	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z23_07240	COG0612	Peptidase, M16
K8Z23_07245	COG0612	Peptidase, M16
K8Z23_07250	COG0300	oxidoreductase activity
K8Z23_07265	COG1426	Protein conserved in bacteria
K8Z23_07270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z23_07290	COG1692	metallophosphoesterase
K8Z23_07295	COG2359	stage V sporulation protein S
K8Z23_07305	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z23_07305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z23_07310	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z23_07320	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z23_07365	COG1396	sequence-specific DNA binding
K8Z23_07380	COG0840	transmembrane signaling receptor activity
K8Z23_07415	COG1725	Transcriptional regulator
K8Z23_07420	COG1131	(ABC) transporter
K8Z23_07445	COG1131	(ABC) transporter
K8Z23_07495	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z23_07500	COG1368	sulfuric ester hydrolase activity
K8Z23_07510	COG3773	Cell wall hydrolase
K8Z23_07520	COG1404	Belongs to the peptidase S8 family
K8Z23_07530	COG0840	transmembrane signaling receptor activity
K8Z23_07545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_07555	COG1346	cytolysis
K8Z23_07570	COG1086	Polysaccharide biosynthesis protein
K8Z23_07590	COG5001	Diguanylate cyclase
K8Z23_07590	COG3300	MHYT domain
K8Z23_07595	COG2267	carboxylic ester hydrolase activity
K8Z23_07610	COG2364	Membrane
K8Z23_07620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z23_07625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z23_07630	COG2169	Transcriptional regulator
K8Z23_07635	COG0708	Exodeoxyribonuclease III
K8Z23_07640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_07645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_07650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_07655	COG1120	ATPase activity
K8Z23_07660	COG2819	hydrolase of the alpha beta superfamily
K8Z23_07680	COG1937	Protein conserved in bacteria
K8Z23_07685	COG2608	mercury ion transmembrane transporter activity
K8Z23_07690	COG2217	Heavy metal translocating P-type atpase
K8Z23_07705	COG2116	formate transmembrane transporter activity
K8Z23_07710	COG1408	metallophosphoesterase
K8Z23_07725	COG1113	amino acid transport
K8Z23_07735	COG2322	membrane
K8Z23_07740	COG1979	alcohol dehydrogenase
K8Z23_07745	COG1349	DNA-binding transcription factor activity
K8Z23_07750	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z23_07755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z23_07755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z23_07755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z23_07760	COG1388	LysM domain
K8Z23_07760	COG3584	3D domain protein
K8Z23_07790	COG0464	growth
K8Z23_07800	COG2860	membrane
K8Z23_07805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z23_07810	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z23_07815	COG0789	Transcriptional regulator
K8Z23_07820	COG0174	glutamine synthetase
K8Z23_07825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z23_07860	COG0741	lytic transglycosylase activity
K8Z23_07865	COG1196	nuclear chromosome segregation
K8Z23_07865	COG0741	lytic transglycosylase activity
K8Z23_07865	COG0739	heme binding
K8Z23_07875	COG1695	Transcriptional regulator
K8Z23_07895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z23_07920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z23_07955	COG1132	(ABC) transporter
K8Z23_07960	COG1132	(ABC) transporter
K8Z23_07985	COG0730	response to heat
K8Z23_08000	COG1346	cytolysis
K8Z23_08010	COG0583	DNA-binding transcription factor activity
K8Z23_08030	COG1131	(ABC) transporter
K8Z23_08040	COG1473	amidohydrolase
K8Z23_08050	COG0785	Cytochrome C biogenesis protein
K8Z23_08055	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z23_08105	COG0010	Belongs to the arginase family
K8Z23_08110	COG1329	Transcriptional regulator
K8Z23_08115	COG1902	pentaerythritol trinitrate reductase activity
K8Z23_08120	COG0069	glutamate synthase activity
K8Z23_08130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z23_08135	COG0346	lactoylglutathione lyase activity
K8Z23_08140	COG0400	carboxylic ester hydrolase activity
K8Z23_08145	COG5002	protein histidine kinase activity
K8Z23_08155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_08190	COG1396	sequence-specific DNA binding
K8Z23_08195	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z23_08200	COG1268	BioY protein
K8Z23_08205	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z23_08210	COG0183	Belongs to the thiolase family
K8Z23_08225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z23_08235	COG2211	Major facilitator Superfamily
K8Z23_08265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z23_08270	COG1132	(ABC) transporter
K8Z23_08275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z23_08300	COG0824	Thioesterase
K8Z23_08305	COG4841	protein insertion into membrane
K8Z23_08325	COG0745	RESPONSE REGULATOR receiver
K8Z23_08330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z23_08335	COG1832	CoA-binding protein
K8Z23_08340	COG0187	DNA topoisomerase II activity
K8Z23_08345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z23_08350	COG0673	inositol 2-dehydrogenase activity
K8Z23_08370	COG1131	(ABC) transporter
K8Z23_08380	COG1595	DNA-templated transcription, initiation
K8Z23_08390	COG1316	TRANSCRIPTIONal
K8Z23_08395	COG1301	dicarboxylic acid transport
K8Z23_08400	COG4166	transmembrane transport
K8Z23_08415	COG4166	transmembrane transport
K8Z23_08420	COG2226	methyltransferase
K8Z23_08455	COG0531	amino acid
K8Z23_08470	COG0697	spore germination
K8Z23_08475	COG3383	formate dehydrogenase (NAD+) activity
K8Z23_08480	COG2427	Protein of unknown function (DUF1641)
K8Z23_08485	COG5609	conserved protein (DUF2294)
K8Z23_08490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z23_08500	COG2116	formate transmembrane transporter activity
K8Z23_08505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z23_08510	COG0303	'Molybdopterin
K8Z23_08515	COG0314	molybdopterin synthase activity
K8Z23_08525	COG0489	protein tyrosine kinase activity
K8Z23_08540	COG3326	Membrane
K8Z23_08545	COG2962	Rard protein
K8Z23_08550	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z23_08555	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z23_08565	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_08570	COG1012	belongs to the aldehyde dehydrogenase family
K8Z23_08580	COG4145	pantothenate transmembrane transporter activity
K8Z23_08595	COG0165	Argininosuccinate lyase
K8Z23_08605	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_08625	COG0494	nUDIX hydrolase
K8Z23_08635	COG0716	FMN binding
K8Z23_08675	COG2720	vancomycin resistance protein
K8Z23_08680	COG2514	catechol 2,3-dioxygenase activity
K8Z23_08690	COG1285	pathogenesis
K8Z23_08700	COG3852	Histidine kinase
K8Z23_08725	COG1876	peptidase activity
K8Z23_08740	COG1309	transcriptional regulator
K8Z23_08745	COG0488	(ABC) transporter
K8Z23_08795	COG0457	Tetratricopeptide repeat
K8Z23_08815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z23_08835	COG0697	spore germination
K8Z23_08845	COG3397	chitin binding
K8Z23_08850	COG0823	Involved in the tonB-independent uptake of proteins
K8Z23_08860	COG0463	Glycosyl transferase, family 2
K8Z23_08865	COG0463	Glycosyl transferase, family 2
K8Z23_08870	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K8Z23_08880	COG1088	dTDP-glucose 4,6-dehydratase activity
K8Z23_08885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K8Z23_08890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K8Z23_08905	COG2089	acid synthase
K8Z23_08915	COG4641	Protein conserved in bacteria
K8Z23_08930	COG1252	NADH dehydrogenase
K8Z23_08950	COG0277	FAD linked oxidase domain protein
K8Z23_08955	COG0385	Bile acid
K8Z23_08965	COG0457	Tetratricopeptide repeat
K8Z23_08975	COG0604	alcohol dehydrogenase
K8Z23_08980	COG0640	Transcriptional regulator
K8Z23_08990	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z23_09005	COG2271	Major facilitator Superfamily
K8Z23_09015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z23_09020	COG1164	Oligoendopeptidase f
K8Z23_09050	COG1193	negative regulation of DNA recombination
K8Z23_09070	COG0583	DNA-binding transcription factor activity
K8Z23_09105	COG3739	integral membrane protein
K8Z23_09110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_09115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_09120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_09125	COG1247	-acetyltransferase
K8Z23_09135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z23_09140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z23_09170	COG2814	Major facilitator Superfamily
K8Z23_09175	COG1113	amino acid transport
K8Z23_09180	COG0604	alcohol dehydrogenase
K8Z23_09185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_09215	COG2072	flavoprotein involved in K transport
K8Z23_09250	COG1151	hydroxylamine reductase activity
K8Z23_09295	COG1191	sigma factor activity
K8Z23_09325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K8Z23_09335	COG1733	regulation of RNA biosynthetic process
K8Z23_09340	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z23_09345	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z23_09355	COG0384	phenazine biosynthesis protein PhzF
K8Z23_09380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_09410	COG0673	inositol 2-dehydrogenase activity
K8Z23_09415	COG2188	Transcriptional regulator
K8Z23_09420	COG1733	regulation of RNA biosynthetic process
K8Z23_09455	COG0814	amino acid
K8Z23_09475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z23_09480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z23_09485	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z23_09490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z23_09495	COG1070	Carbohydrate kinase
K8Z23_09500	COG2706	6-phosphogluconolactonase activity
K8Z23_09505	COG3813	Protein conserved in bacteria
K8Z23_09510	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z23_09525	COG0697	spore germination
K8Z23_09550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z23_09560	COG0789	Transcriptional regulator
K8Z23_09565	COG1253	flavin adenine dinucleotide binding
K8Z23_09595	COG0477	Major facilitator Superfamily
K8Z23_09605	COG0500	methyltransferase
K8Z23_09640	COG0628	permease
K8Z23_09655	COG0110	maltose O-acetyltransferase activity
K8Z23_09660	COG0738	Major facilitator superfamily
K8Z23_09665	COG1940	carbohydrate kinase activity
K8Z23_09670	COG0346	lactoylglutathione lyase activity
K8Z23_09680	COG1051	belongs to the nudix hydrolase family
K8Z23_09695	COG2365	Tyrosine phosphatase family
K8Z23_09705	COG1011	Hydrolase
K8Z23_09730	COG1131	(ABC) transporter
K8Z23_09740	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_09770	COG0778	Nitroreductase
K8Z23_09775	COG1733	regulation of RNA biosynthetic process
K8Z23_09800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z23_09805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z23_09815	COG2356	endonuclease I
K8Z23_09820	COG1288	antiporter activity
K8Z23_09875	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z23_09890	COG2031	fatty acid transporter
K8Z23_09900	COG2814	Major facilitator Superfamily
K8Z23_09905	COG1846	Transcriptional regulator
K8Z23_09920	COG0477	Major facilitator Superfamily
K8Z23_09930	COG2843	Capsule synthesis protein
K8Z23_09935	COG1876	peptidase activity
K8Z23_09980	COG5444	nuclease activity
K8Z23_09995	COG5444	nuclease activity
K8Z23_10015	COG5444	nuclease activity
K8Z23_10055	COG2814	Major facilitator Superfamily
K8Z23_10070	COG3409	Peptidoglycan-binding domain 1 protein
K8Z23_10070	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z23_10090	COG2207	Transcriptional regulator
K8Z23_10090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_10095	COG0662	Cupin 2, conserved barrel domain protein
K8Z23_10115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z23_10135	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z23_10150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_10160	COG5002	protein histidine kinase activity
K8Z23_10160	COG3850	Histidine kinase
K8Z23_10180	COG0577	efflux transmembrane transporter activity
K8Z23_10205	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z23_10230	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z23_10240	COG2814	Major facilitator Superfamily
K8Z23_10275	COG1136	(ABC) transporter
K8Z23_10285	COG0277	FAD linked oxidase domain protein
K8Z23_10325	COG3850	Histidine kinase
K8Z23_10325	COG5002	protein histidine kinase activity
K8Z23_10330	COG0745	RESPONSE REGULATOR receiver
K8Z23_10355	COG0346	lactoylglutathione lyase activity
K8Z23_10375	COG0640	Transcriptional regulator
K8Z23_10380	COG0798	PFAM Bile acid sodium symporter
K8Z23_10405	COG1121	(ABC) transporter
K8Z23_10410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z23_10415	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z23_10420	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z23_10435	COG0697	spore germination
K8Z23_10450	COG5609	conserved protein (DUF2294)
K8Z23_10455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z23_10465	COG0288	reversible hydration of carbon dioxide
K8Z23_10470	COG0415	Belongs to the DNA photolyase family
K8Z23_10495	COG1073	alpha beta
K8Z23_10515	COG0598	Magnesium transport protein CorA
K8Z23_10530	COG1476	TRANSCRIPTIONal
K8Z23_10540	COG1846	Transcriptional regulator
K8Z23_10545	COG0583	DNA-binding transcription factor activity
K8Z23_10565	COG1335	isochorismatase
K8Z23_10570	COG2267	carboxylic ester hydrolase activity
K8Z23_10575	COG0737	Belongs to the 5'-nucleotidase family
K8Z23_10590	COG2124	cytochrome p450
K8Z23_10600	COG1115	amino acid carrier protein
K8Z23_10610	COG4191	Histidine kinase
K8Z23_10615	COG0784	Response regulator, receiver
K8Z23_10620	COG0697	spore germination
K8Z23_10625	COG0531	amino acid
K8Z23_10635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z23_10640	COG0531	amino acid
K8Z23_10645	COG0322	excinuclease ABC activity
K8Z23_10660	COG2207	Transcriptional regulator
K8Z23_10685	COG5002	protein histidine kinase activity
K8Z23_10715	COG1396	sequence-specific DNA binding
K8Z23_10720	COG0252	asparaginase activity
K8Z23_10725	COG1027	Aspartate ammonia-lyase
K8Z23_10735	COG1063	alcohol dehydrogenase
K8Z23_10765	COG1113	amino acid transport
K8Z23_10770	COG1280	lysine exporter protein (LysE YggA)
K8Z23_10775	COG3403	YqcI/YcgG family
K8Z23_10780	COG5577	PFAM Coat F domain
K8Z23_10800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_10805	COG3848	Pyruvate phosphate dikinase
K8Z23_10805	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z23_10825	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z23_10845	COG3314	Sporulation integral membrane protein YlbJ
K8Z23_10860	COG1960	acyl-CoA dehydrogenase activity
K8Z23_10870	COG0640	Transcriptional regulator
K8Z23_10885	COG1414	Transcriptional regulator
K8Z23_10890	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z23_10895	COG1984	allophanate hydrolase subunit 2
K8Z23_10925	COG0768	penicillin binding
K8Z23_10960	COG1329	Transcriptional regulator
K8Z23_11010	COG0833	amino acid
K8Z23_11020	COG0730	response to heat
K8Z23_11060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_11065	COG0697	spore germination
K8Z23_11070	COG2816	NAD+ diphosphatase activity
K8Z23_11080	COG0456	acetyltransferase
K8Z23_11085	COG2207	Transcriptional regulator
K8Z23_11105	COG3831	ATPase activity
K8Z23_11105	COG4884	unkown
K8Z23_11125	COG1846	Transcriptional regulator
K8Z23_11130	COG0778	Nitroreductase
K8Z23_11205	COG0753	catalase activity
K8Z23_11210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z23_11235	COG0714	Associated with various cellular activities
K8Z23_11255	COG0346	lactoylglutathione lyase activity
K8Z23_11280	COG3655	Transcriptional regulator
K8Z23_11290	COG1785	Belongs to the alkaline phosphatase family
K8Z23_11295	COG2720	vancomycin resistance protein
K8Z23_11305	COG3239	Fatty acid desaturase
K8Z23_11320	COG0833	amino acid
K8Z23_11325	COG1414	Transcriptional regulator
K8Z23_11330	COG4187	Peptidase family M20/M25/M40
K8Z23_11335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z23_11350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z23_11365	COG2329	Antibiotic biosynthesis monooxygenase
K8Z23_11395	COG1070	Carbohydrate kinase
K8Z23_11400	COG2390	Transcriptional regulator
K8Z23_11405	COG1129	ABC transporter
K8Z23_11410	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z23_11420	COG1879	ABC-type sugar transport system periplasmic component
K8Z23_11490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z23_11490	COG1605	Chorismate mutase
K8Z23_11505	COG0287	Prephenate dehydrogenase
K8Z23_11520	COG1309	transcriptional regulator
K8Z23_11525	COG1033	growth of symbiont in host cell
K8Z23_11525	COG2409	Drug exporters of the RND superfamily
K8Z23_11530	COG0488	(ABC) transporter
K8Z23_11535	COG1368	sulfuric ester hydrolase activity
K8Z23_11540	COG0861	Integral membrane protein TerC family
K8Z23_11570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_11575	COG0346	lactoylglutathione lyase activity
K8Z23_11580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z23_11585	COG4912	Dna alkylation repair
K8Z23_11605	COG2318	DinB family
K8Z23_11610	COG0697	spore germination
K8Z23_11620	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z23_11650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z23_11655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z23_11675	COG0628	permease
K8Z23_11720	COG1131	(ABC) transporter
K8Z23_11735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8Z23_11745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z23_11750	COG0436	Aminotransferase
K8Z23_11800	COG2261	transglycosylase associated protein
K8Z23_11825	COG2814	Major facilitator Superfamily
K8Z23_11825	COG0477	Major facilitator Superfamily
K8Z23_11830	COG4533	DNA binding
K8Z23_11835	COG0789	Transcriptional regulator
K8Z23_11840	COG1664	Polymer-forming cytoskeletal
K8Z23_11850	COG2814	Major facilitator Superfamily
K8Z23_11890	COG1307	EDD domain protein, DegV family
K8Z23_11895	COG1164	Oligoendopeptidase f
K8Z23_11920	COG0745	RESPONSE REGULATOR receiver
K8Z23_11925	COG3850	Histidine kinase
K8Z23_11925	COG5002	protein histidine kinase activity
K8Z23_11970	COG0667	Aldo Keto reductase
K8Z23_11985	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z23_11995	COG4166	transmembrane transport
K8Z23_12000	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z23_12010	COG0586	Pfam SNARE associated Golgi protein
K8Z23_12050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z23_12055	COG3938	Belongs to the proline racemase family
K8Z23_12065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z23_12070	COG1012	belongs to the aldehyde dehydrogenase family
K8Z23_12075	COG1115	amino acid carrier protein
K8Z23_12080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z23_12095	COG3397	chitin binding
K8Z23_12110	COG4637	Psort location Cytoplasmic, score
K8Z23_12155	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z23_12160	COG2105	PFAM AIG2 family protein
K8Z23_12170	COG3973	AAA domain
K8Z23_12175	COG0456	acetyltransferase
K8Z23_12225	COG2315	Protein conserved in bacteria
K8Z23_12230	COG2226	methyltransferase
K8Z23_12235	COG2205	protein histidine kinase activity
K8Z23_12245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K8Z23_12260	COG3397	chitin binding
K8Z23_12280	COG2153	protein acetylation
K8Z23_12310	COG0517	IMP dehydrogenase activity
K8Z23_12310	COG4175	Glycine betaine
K8Z23_12315	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z23_12345	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_12355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z23_12360	COG0022	dehydrogenase e1 component
K8Z23_12365	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z23_12370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z23_12385	COG1959	2 iron, 2 sulfur cluster binding
K8Z23_12400	COG1349	DNA-binding transcription factor activity
K8Z23_12415	COG3284	Transcriptional regulator
K8Z23_12435	COG1309	transcriptional regulator
K8Z23_12475	COG2959	enzyme of heme biosynthesis
K8Z23_12490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_12525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_12530	COG0697	spore germination
K8Z23_12535	COG0201	protein transport
K8Z23_12555	COG0737	Belongs to the 5'-nucleotidase family
K8Z23_12560	COG3227	Zinc metalloprotease (Elastase)
K8Z23_12565	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z23_12580	COG0076	glutamate decarboxylase activity
K8Z23_12585	COG0657	acetylesterase activity
K8Z23_12590	COG1073	alpha beta
K8Z23_12595	COG0577	efflux transmembrane transporter activity
K8Z23_12600	COG1136	(ABC) transporter
K8Z23_12615	COG5002	protein histidine kinase activity
K8Z23_12620	COG0745	RESPONSE REGULATOR receiver
K8Z23_12625	COG1011	Hydrolase
K8Z23_12650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z23_12675	COG1131	(ABC) transporter
K8Z23_12695	COG1819	glycosyl
K8Z23_12700	COG1819	glycosyl
K8Z23_12735	COG0322	excinuclease ABC activity
K8Z23_12775	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z23_12795	COG3878	Protein conserved in bacteria
K8Z23_12820	COG1051	belongs to the nudix hydrolase family
K8Z23_12825	COG0592	DNA-directed DNA polymerase activity
K8Z23_12840	COG2223	nitrite transmembrane transporter activity
K8Z23_12850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z23_12860	COG0494	nUDIX hydrolase
K8Z23_12885	COG0697	spore germination
K8Z23_12890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_12910	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z23_12970	COG0768	penicillin binding
K8Z23_12975	COG0671	phosphoesterase, PA-phosphatase related
K8Z23_12980	COG0604	alcohol dehydrogenase
K8Z23_12985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z23_13010	COG2169	Transcriptional regulator
K8Z23_13070	COG2205	protein histidine kinase activity
K8Z23_13095	COG1794	racemase activity, acting on amino acids and derivatives
K8Z23_13100	COG1819	glycosyl
K8Z23_13110	COG0768	penicillin binding
K8Z23_13115	COG5002	protein histidine kinase activity
K8Z23_13120	COG0561	phosphatase activity
K8Z23_13155	COG2124	cytochrome p450
K8Z23_13200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K8Z23_13205	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z23_13280	COG0740	serine-type endopeptidase activity
K8Z23_13325	COG0582	viral genome integration into host DNA
K8Z23_13390	COG1484	DNA-dependent DNA replication
K8Z23_13420	COG1396	sequence-specific DNA binding
K8Z23_13440	COG0582	viral genome integration into host DNA
K8Z23_13470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z23_13480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_13505	COG0577	efflux transmembrane transporter activity
K8Z23_13510	COG1136	(ABC) transporter
K8Z23_13525	COG0488	(ABC) transporter
K8Z23_13530	COG0667	Aldo Keto reductase
K8Z23_13535	COG0583	DNA-binding transcription factor activity
K8Z23_13540	COG2205	protein histidine kinase activity
K8Z23_13545	COG0745	RESPONSE REGULATOR receiver
K8Z23_13555	COG3773	Cell wall hydrolase
K8Z23_13560	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z23_13570	COG3386	PFAM SMP-30 Gluconolaconase
K8Z23_13580	COG0693	protein deglycase activity
K8Z23_13590	COG2323	membrane
K8Z23_13615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_13655	COG1733	regulation of RNA biosynthetic process
K8Z23_13660	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_13670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z23_13700	COG2207	Transcriptional regulator
K8Z23_13705	COG3227	Zinc metalloprotease (Elastase)
K8Z23_13720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z23_13750	COG1686	Belongs to the peptidase S11 family
K8Z23_13770	COG0572	uridine kinase
K8Z23_13790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z23_13795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z23_13800	COG1024	Enoyl-CoA hydratase
K8Z23_13805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z23_13810	COG0511	ligase activity, forming carbon-carbon bonds
K8Z23_13815	COG0439	Biotin carboxylase
K8Z23_13820	COG1960	acyl-CoA dehydrogenase activity
K8Z23_13835	COG1309	transcriptional regulator
K8Z23_13845	COG1131	(ABC) transporter
K8Z23_13855	COG1408	metallophosphoesterase
K8Z23_13865	COG0768	penicillin binding
K8Z23_13870	COG0768	penicillin binding
K8Z23_13880	COG1595	DNA-templated transcription, initiation
K8Z23_13885	COG0768	penicillin binding
K8Z23_13945	COG1404	Belongs to the peptidase S8 family
K8Z23_13955	COG4585	Histidine kinase
K8Z23_13960	COG0367	asparagine synthase
K8Z23_13965	COG1309	transcriptional regulator
K8Z23_13985	COG1396	sequence-specific DNA binding
K8Z23_14030	COG2814	Major facilitator Superfamily
K8Z23_14035	COG2234	aminopeptidase activity
K8Z23_14045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z23_14060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K8Z23_14065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z23_14070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K8Z23_14085	COG0456	acetyltransferase
K8Z23_14095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_14105	COG0741	lytic transglycosylase activity
K8Z23_14150	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_14180	COG2814	Major facilitator Superfamily
K8Z23_14195	COG1686	Belongs to the peptidase S11 family
K8Z23_14205	COG0730	response to heat
K8Z23_14215	COG2002	toxin-antitoxin pair type II binding
K8Z23_14240	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z23_14280	COG2226	methyltransferase
K8Z23_14290	COG0500	methyltransferase
K8Z23_14290	COG3615	Tellurite resistance protein tehB
K8Z23_14415	COG1309	transcriptional regulator
K8Z23_14435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_14450	COG1846	Transcriptional regulator
K8Z23_14460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K8Z23_14470	COG2971	BadF BadG BcrA BcrD
K8Z23_14495	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z23_14525	COG1595	DNA-templated transcription, initiation
K8Z23_14530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z23_14560	COG1396	sequence-specific DNA binding
K8Z23_14585	COG1132	(ABC) transporter
K8Z23_14590	COG1132	(ABC) transporter
K8Z23_14605	COG2258	MOSC domain
K8Z23_14610	COG0583	DNA-binding transcription factor activity
K8Z23_14625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z23_14630	COG0583	DNA-binding transcription factor activity
K8Z23_14670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_14680	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z23_14705	COG1247	-acetyltransferase
K8Z23_14740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z23_14755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z23_14800	COG1136	(ABC) transporter
K8Z23_14805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z23_14810	COG1187	pseudouridine synthase activity
K8Z23_14830	COG1115	amino acid carrier protein
K8Z23_14840	COG2318	DinB family
K8Z23_14850	COG0776	regulation of translation
K8Z23_14865	COG2814	Major facilitator Superfamily
K8Z23_14870	COG3251	PFAM MbtH domain protein
K8Z23_14875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z23_14880	COG3433	isochorismatase activity
K8Z23_14880	COG1535	isochorismatase
K8Z23_14885	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z23_14890	COG1169	isochorismate synthase
K8Z23_14895	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_14900	COG2223	nitrite transmembrane transporter activity
K8Z23_14920	COG0419	ATPase involved in DNA repair
K8Z23_14925	COG0420	3'-5' exonuclease activity
K8Z23_14940	COG1024	Enoyl-CoA hydratase
K8Z23_14945	COG1280	lysine exporter protein (LysE YggA)
K8Z23_14955	COG2084	Dehydrogenase
K8Z23_14960	COG1960	acyl-CoA dehydrogenase activity
K8Z23_14965	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z23_14970	COG2079	MmgE PrpD family protein
K8Z23_14975	COG0372	Belongs to the citrate synthase family
K8Z23_14980	COG4841	protein insertion into membrane
K8Z23_14985	COG2814	Major facilitator Superfamily
K8Z23_14995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z23_14995	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z23_15015	COG0300	oxidoreductase activity
K8Z23_15115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z23_15120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z23_15125	COG0671	phosphoesterase, PA-phosphatase related
K8Z23_15135	COG0515	serine threonine protein kinase
K8Z23_15135	COG3064	Membrane
K8Z23_15135	COG4991	sh3 domain protein
K8Z23_15170	COG1509	lysine 2,3-aminomutase activity
K8Z23_15175	COG3829	transcription factor binding
K8Z23_15180	COG0456	acetyltransferase
K8Z23_15185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z23_15190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z23_15195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z23_15200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z23_15215	COG5506	Protein of unknown function (DUF1694)
K8Z23_15220	COG1012	belongs to the aldehyde dehydrogenase family
K8Z23_15225	COG1253	flavin adenine dinucleotide binding
K8Z23_15260	COG1174	glycine betaine transport
K8Z23_15265	COG0517	IMP dehydrogenase activity
K8Z23_15265	COG1125	glycine betaine transport
K8Z23_15300	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z23_15310	COG1070	Carbohydrate kinase
K8Z23_15325	COG1064	alcohol dehydrogenase
K8Z23_15330	COG0384	phenazine biosynthesis protein PhzF
K8Z23_15335	COG1737	Transcriptional regulator
K8Z23_15340	COG2197	response regulator
K8Z23_15345	COG4585	Histidine kinase
K8Z23_15345	COG2203	Gaf domain
K8Z23_15350	COG0668	transmembrane transport
K8Z23_15355	COG1051	belongs to the nudix hydrolase family
K8Z23_15360	COG1335	isochorismatase
K8Z23_15375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z23_15380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_15385	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z23_15400	COG0367	asparagine synthase
K8Z23_15405	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z23_15410	COG1999	signal sequence binding
K8Z23_15420	COG1307	EDD domain protein, DegV family
K8Z23_15430	COG0805	protein transport
K8Z23_15440	COG1272	protein, Hemolysin III
K8Z23_15445	COG0204	Acyl-transferase
K8Z23_15455	COG0768	penicillin binding
K8Z23_15470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z23_15485	COG0546	phosphoglycolate phosphatase activity
K8Z23_15500	COG1131	(ABC) transporter
K8Z23_15510	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z23_15525	COG0456	acetyltransferase
K8Z23_15535	COG1794	racemase activity, acting on amino acids and derivatives
K8Z23_15545	COG2610	gluconate transmembrane transporter activity
K8Z23_15570	COG0733	neurotransmitter:sodium symporter activity
K8Z23_15575	COG0017	Asparaginyl-tRNA synthetase
K8Z23_15605	COG0018	arginyl-trna synthetase
K8Z23_15610	COG2136	Putative SAM-dependent methyltransferase
K8Z23_15610	COG2521	methyltransferase
K8Z23_15625	COG1413	lyase activity
K8Z23_15640	COG0629	single-stranded DNA binding
K8Z23_15655	COG0488	(ABC) transporter
K8Z23_15660	COG1418	mRNA catabolic process
K8Z23_15675	COG0457	Tetratricopeptide repeat
K8Z23_15690	COG2359	stage V sporulation protein S
K8Z23_15725	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z23_15730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z23_15735	COG2146	nitrite reductase [NAD(P)H] activity
K8Z23_15740	COG1587	Uroporphyrinogen-III synthase
K8Z23_15740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z23_15745	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
K8Z23_15750	COG1648	precorrin-2 dehydrogenase activity
K8Z23_15765	COG2223	nitrite transmembrane transporter activity
K8Z23_15775	COG0314	molybdopterin synthase activity
K8Z23_15780	COG0303	'Molybdopterin
K8Z23_15785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z23_15790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z23_15795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z23_15800	COG2181	nitrate reductase activity
K8Z23_15805	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z23_15810	COG1140	nitrate reductase beta subunit
K8Z23_15815	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z23_15820	COG0714	Associated with various cellular activities
K8Z23_15825	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z23_15830	COG1305	Transglutaminase-like
K8Z23_15835	COG0386	Belongs to the glutathione peroxidase family
K8Z23_15850	COG0426	domain, Protein
K8Z23_15850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z23_15860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K8Z23_15870	COG1595	DNA-templated transcription, initiation
K8Z23_15875	COG0604	alcohol dehydrogenase
K8Z23_15885	COG0346	lactoylglutathione lyase activity
K8Z23_15890	COG1082	Xylose isomerase domain protein TIM barrel
K8Z23_15910	COG2226	methyltransferase
K8Z23_15935	COG3874	Sporulation protein YtfJ
K8Z23_16035	COG0456	acetyltransferase
K8Z23_16065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_16070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_16075	COG1819	glycosyl
K8Z23_16090	COG4106	trans-aconitate 2-methyltransferase activity
K8Z23_16095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z23_16105	COG2814	Major facilitator Superfamily
K8Z23_16110	COG1846	Transcriptional regulator
K8Z23_16125	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z23_16140	COG2211	Major facilitator Superfamily
K8Z23_16155	COG1876	peptidase activity
K8Z23_16165	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z23_16185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z23_16190	COG1114	Component of the transport system for branched-chain amino acids
K8Z23_16215	COG1253	flavin adenine dinucleotide binding
K8Z23_16220	COG2839	Protein conserved in bacteria
K8Z23_16225	COG0702	epimerase
K8Z23_16240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z23_16250	COG1607	acyl-coa hydrolase
K8Z23_16255	COG3689	TIGRFAM TIGR03943 family protein
K8Z23_16260	COG0701	Predicted permease
K8Z23_16270	COG2244	polysaccharide biosynthetic process
K8Z23_16275	COG0586	Pfam SNARE associated Golgi protein
K8Z23_16280	COG1051	belongs to the nudix hydrolase family
K8Z23_16285	COG5337	Spore coat protein CotH
K8Z23_16295	COG0406	alpha-ribazole phosphatase activity
K8Z23_16310	COG4166	transmembrane transport
K8Z23_16320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z23_16330	COG0702	epimerase
K8Z23_16340	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z23_16345	COG0456	acetyltransferase
K8Z23_16350	COG0523	cobalamin synthesis protein
K8Z23_16355	COG4989	oxidoreductase activity
K8Z23_16360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_16365	COG1231	oxidoreductase activity
K8Z23_16375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z23_16390	COG0783	Belongs to the Dps family
K8Z23_16395	COG3949	Membrane
K8Z23_16410	COG0840	transmembrane signaling receptor activity
K8Z23_16440	COG0667	Aldo Keto reductase
K8Z23_16445	COG0640	Transcriptional regulator
K8Z23_16450	COG1404	Belongs to the peptidase S8 family
K8Z23_16455	COG2002	toxin-antitoxin pair type II binding
K8Z23_16460	COG0577	efflux transmembrane transporter activity
K8Z23_16495	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z23_16505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_16510	COG1279	arginine transmembrane transporter activity
K8Z23_16515	COG2814	Major facilitator Superfamily
K8Z23_16525	COG1082	Xylose isomerase domain protein TIM barrel
K8Z23_16535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z23_16555	COG1247	-acetyltransferase
K8Z23_16560	COG1285	pathogenesis
K8Z23_16575	COG1316	TRANSCRIPTIONal
K8Z23_16600	COG0460	homoserine dehydrogenase
K8Z23_16630	COG4122	O-methyltransferase activity
K8Z23_16640	COG0300	oxidoreductase activity
K8Z23_16645	COG5002	protein histidine kinase activity
K8Z23_16650	COG0745	RESPONSE REGULATOR receiver
K8Z23_16655	COG1132	(ABC) transporter
K8Z23_16820	COG0305	Participates in initiation and elongation during chromosome replication
K8Z23_16850	COG3646	Phage regulatory protein
K8Z23_16920	COG1132	(ABC) transporter
K8Z23_16930	COG1388	LysM domain
K8Z23_16930	COG0791	NLP P60 protein
K8Z23_16945	COG1686	Belongs to the peptidase S11 family
K8Z23_16985	COG1216	Glycosyl transferase, family 2
K8Z23_16995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z23_17000	COG4988	ABC transporter
K8Z23_17005	COG1294	oxidase, subunit
K8Z23_17010	COG1271	oxidase subunit
K8Z23_17030	COG1942	4-Oxalocrotonate Tautomerase
K8Z23_17040	COG0583	DNA-binding transcription factor activity
K8Z23_17060	COG0411	ABC transporter
K8Z23_17070	COG0523	cobalamin synthesis protein
K8Z23_17075	COG1231	oxidoreductase activity
K8Z23_17085	COG0628	permease
K8Z23_17095	COG0778	Nitroreductase
K8Z23_17100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z23_17105	COG1959	2 iron, 2 sulfur cluster binding
K8Z23_17110	COG0583	DNA-binding transcription factor activity
K8Z23_17115	COG0697	spore germination
K8Z23_17120	COG4549	nuclear export factor GLE1
K8Z23_17125	COG2372	response to copper ion
K8Z23_17125	COG1276	copper resistance
K8Z23_17135	COG1114	Component of the transport system for branched-chain amino acids
K8Z23_17160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z23_17170	COG2132	Multicopper oxidase
K8Z23_17180	COG0006	proline dipeptidase activity
K8Z23_17190	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z23_17230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z23_17235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z23_17245	COG2390	Transcriptional regulator
K8Z23_17250	COG1309	transcriptional regulator
K8Z23_17265	COG0456	acetyltransferase
K8Z23_17280	COG2309	aminopeptidase activity
K8Z23_17305	COG0531	amino acid
K8Z23_17310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z23_17325	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z23_17330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z23_17335	COG4166	transmembrane transport
K8Z23_17355	COG0427	acetyl-CoA hydrolase
K8Z23_17360	COG3279	Response regulator of the LytR AlgR family
K8Z23_17375	COG3384	dioxygenase
K8Z23_17380	COG2814	Major facilitator Superfamily
K8Z23_17405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z23_17425	COG0028	Belongs to the TPP enzyme family
K8Z23_17430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z23_17440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z23_17460	COG2323	membrane
K8Z23_17465	COG5566	PFAM Mor transcription activator
K8Z23_17475	COG0733	neurotransmitter:sodium symporter activity
K8Z23_17495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z23_17500	COG2223	nitrite transmembrane transporter activity
K8Z23_17505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z23_17515	COG0477	Major facilitator Superfamily
K8Z23_17525	COG1695	Transcriptional regulator
K8Z23_17540	COG2814	Major facilitator Superfamily
K8Z23_17585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z23_17590	COG0784	Response regulator, receiver
K8Z23_17595	COG4191	Histidine kinase
K8Z23_17600	COG0281	malic enzyme
K8Z23_17605	COG1027	Aspartate ammonia-lyase
K8Z23_17615	COG0528	UMP kinase activity
K8Z23_17620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z23_17635	COG1131	(ABC) transporter
K8Z23_17670	COG2733	membrane
K8Z23_17705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z23_17710	COG0785	Cytochrome C biogenesis protein
K8Z23_17730	COG3340	Belongs to the peptidase S51 family
K8Z23_17735	COG0534	Mate efflux family protein
K8Z23_17770	COG0789	Transcriptional regulator
K8Z23_17775	COG1757	Na H antiporter
K8Z23_17780	COG1216	Glycosyl transferase, family 2
K8Z23_17780	COG0438	transferase activity, transferring glycosyl groups
K8Z23_17790	COG0701	Predicted permease
K8Z23_17795	COG0523	cobalamin synthesis protein
K8Z23_17830	COG0367	asparagine synthase
K8Z23_17840	COG1846	Transcriptional regulator
K8Z23_17860	COG0406	alpha-ribazole phosphatase activity
K8Z23_17915	COG3842	ATPase activity
K8Z23_17920	COG0583	DNA-binding transcription factor activity
K8Z23_17945	COG1215	transferase activity, transferring glycosyl groups
K8Z23_17950	COG2329	Antibiotic biosynthesis monooxygenase
K8Z23_17980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z23_17985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z23_17990	COG4786	Flagellar basal body rod
K8Z23_17995	COG1419	protein localization to endoplasmic reticulum
K8Z23_18000	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z23_18005	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z23_18015	COG1987	bacterial-type flagellum assembly
K8Z23_18020	COG1338	Plays a role in the flagellum-specific transport system
K8Z23_18030	COG1776	CheC inhibitor of MCP methylation
K8Z23_18030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z23_18035	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z23_18045	COG0741	lytic transglycosylase activity
K8Z23_18050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z23_18055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z23_18065	COG0784	Response regulator, receiver
K8Z23_18065	COG0835	chemotaxis
K8Z23_18080	COG1749	Flagellar hook protein flgE
K8Z23_18100	COG1157	protein secretion by the type III secretion system
K8Z23_18110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z23_18115	COG1766	The M ring may be actively involved in energy transduction
K8Z23_18125	COG1558	bacterial-type flagellum-dependent cell motility
K8Z23_18130	COG1815	bacterial-type flagellum-dependent cell motility
K8Z23_18145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K8Z23_18150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z23_18155	COG1256	bacterial-type flagellum assembly
K8Z23_18175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z23_18190	COG1776	CheC inhibitor of MCP methylation
K8Z23_18190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z23_18195	COG0643	Histidine kinase
K8Z23_18195	COG2198	Histidine kinase
K8Z23_18200	COG2201	protein-glutamate methylesterase activity
K8Z23_18205	COG1360	Flagellar Motor Protein
K8Z23_18210	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z23_18220	COG1923	regulation of RNA biosynthetic process
K8Z23_18260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z23_18265	COG2323	membrane
K8Z23_18275	COG0789	Transcriptional regulator
K8Z23_18275	COG4978	Transcriptional regulator
K8Z23_18280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z23_18285	COG0475	glutathione-regulated potassium exporter activity
K8Z23_18295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z23_18300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z23_18320	COG1280	lysine exporter protein (LysE YggA)
K8Z23_18325	COG3403	YqcI/YcgG family
K8Z23_18360	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z23_18380	COG0454	-acetyltransferase
K8Z23_18395	COG0438	transferase activity, transferring glycosyl groups
K8Z23_18400	COG1215	transferase activity, transferring glycosyl groups
K8Z23_18415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z23_18440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z23_18455	COG0754	glutathionylspermidine amidase activity
K8Z23_18490	COG0456	acetyltransferase
K8Z23_18500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z23_18520	COG2233	PERMEase
K8Z23_18530	COG0024	Methionine aminopeptidase
K8Z23_18550	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z23_18555	COG1199	ATP-dependent helicase activity
K8Z23_18565	COG0116	Belongs to the methyltransferase superfamily
K8Z23_18620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z23_18620	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z23_18630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z23_18635	COG3935	DnaD domain protein
K8Z23_18655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z23_18655	COG1199	ATP-dependent helicase activity
K8Z23_18690	COG0438	transferase activity, transferring glycosyl groups
K8Z23_18710	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z23_18715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_18725	COG2738	Putative neutral zinc metallopeptidase
K8Z23_18740	COG4347	Protein of unknown function (DUF1405)
K8Z23_18745	COG2010	Cytochrome c
K8Z23_18745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z23_18750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z23_18770	COG0457	Tetratricopeptide repeat
K8Z23_18815	COG0142	geranyltranstransferase activity
K8Z23_18825	COG0142	geranyltranstransferase activity
K8Z23_18840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z23_18910	COG0252	asparaginase activity
K8Z23_18915	COG0492	ferredoxin-NADP+ reductase activity
K8Z23_18935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z23_18945	COG0789	Transcriptional regulator
K8Z23_18950	COG1408	metallophosphoesterase
K8Z23_18960	COG1266	CAAX protease self-immunity
K8Z23_18965	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z23_18975	COG1141	Ferredoxin
K8Z23_18980	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z23_18995	COG2096	Adenosyltransferase
K8Z23_19000	COG5002	protein histidine kinase activity
K8Z23_19005	COG0745	RESPONSE REGULATOR receiver
K8Z23_19010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z23_19015	COG1333	cytochrome c biogenesis protein
K8Z23_19025	COG1187	pseudouridine synthase activity
K8Z23_19030	COG0700	Nucleoside recognition
K8Z23_19035	COG2715	membrane protein required for spore maturation
K8Z23_19040	COG1686	Belongs to the peptidase S11 family
K8Z23_19045	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z23_19060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z23_19060	COG0392	lysyltransferase activity
K8Z23_19075	COG5002	protein histidine kinase activity
K8Z23_19080	COG0582	viral genome integration into host DNA
K8Z23_19090	COG1801	Protein of unknown function DUF72
K8Z23_19095	COG3852	Histidine kinase
K8Z23_19110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z23_19115	COG1392	Phosphate transport regulator
K8Z23_19120	COG0306	phosphate transporter
K8Z23_19125	COG0730	response to heat
K8Z23_19175	COG1114	Component of the transport system for branched-chain amino acids
K8Z23_19185	COG2197	response regulator
K8Z23_19190	COG4585	Histidine kinase
K8Z23_19195	COG4758	membrane
K8Z23_19210	COG1757	Na H antiporter
K8Z23_19235	COG0733	neurotransmitter:sodium symporter activity
K8Z23_19240	COG1648	precorrin-2 dehydrogenase activity
K8Z23_19260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z23_19265	COG0529	Catalyzes the synthesis of activated sulfate
K8Z23_19285	COG0019	diaminopimelate decarboxylase activity
K8Z23_19295	COG1368	sulfuric ester hydrolase activity
K8Z23_19300	COG1183	phosphatidylcholine synthase activity
K8Z23_19315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z23_19390	COG0440	acetolactate synthase activity
K8Z23_19395	COG0028	Belongs to the TPP enzyme family
K8Z23_19400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z23_19420	COG3874	Sporulation protein YtfJ
K8Z23_19425	COG4709	membrane
K8Z23_19430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z23_19445	COG1301	dicarboxylic acid transport
K8Z23_19455	COG1846	Transcriptional regulator
K8Z23_19510	COG0716	FMN binding
K8Z23_19535	COG1696	Membrane protein involved in D-alanine export
K8Z23_19545	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z23_19550	COG2070	2-Nitropropane dioxygenase
K8Z23_19555	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z23_19565	COG1335	isochorismatase
K8Z23_19575	COG1522	sequence-specific DNA binding
K8Z23_19595	COG1131	(ABC) transporter
K8Z23_19605	COG1131	(ABC) transporter
K8Z23_19610	COG1725	Transcriptional regulator
K8Z23_19615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z23_19625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z23_19630	COG1780	Probably involved in ribonucleotide reductase function
K8Z23_19660	COG4873	Protein conserved in bacteria
K8Z23_19675	COG0720	synthase
K8Z23_19685	COG5002	protein histidine kinase activity
K8Z23_19695	COG2318	DinB family
K8Z23_19705	COG1846	Transcriptional regulator
K8Z23_19710	COG3852	Histidine kinase
K8Z23_19720	COG2861	carbohydrate metabolic process
K8Z23_19730	COG0235	Class ii aldolase
K8Z23_19740	COG1349	DNA-binding transcription factor activity
K8Z23_19765	COG3842	ATPase activity
K8Z23_19770	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z23_19785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z23_19795	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z23_19800	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_19820	COG2030	dehydratase
K8Z23_19830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z23_19835	COG0861	Integral membrane protein TerC family
K8Z23_19840	COG2116	formate transmembrane transporter activity
K8Z23_19850	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z23_19870	COG2186	Transcriptional regulator
K8Z23_19875	COG5002	protein histidine kinase activity
K8Z23_19880	COG0745	RESPONSE REGULATOR receiver
K8Z23_19890	COG3835	regulator
K8Z23_19895	COG0277	FAD linked oxidase domain protein
K8Z23_19900	COG0247	lactate metabolic process
K8Z23_19905	COG2340	Cysteine-rich secretory protein family
K8Z23_19915	COG0564	pseudouridine synthase activity
K8Z23_19925	COG2409	Drug exporters of the RND superfamily
K8Z23_19930	COG0671	phosphoesterase, PA-phosphatase related
K8Z23_19940	COG1177	transmembrane transport
K8Z23_19945	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z23_19955	COG1012	belongs to the aldehyde dehydrogenase family
K8Z23_19990	COG0681	Belongs to the peptidase S26 family
K8Z23_19995	COG1686	Belongs to the peptidase S11 family
K8Z23_20005	COG2226	methyltransferase
K8Z23_20025	COG1668	transmembrane transport
K8Z23_20030	COG4152	abc transporter atp-binding protein
K8Z23_20060	COG1476	TRANSCRIPTIONal
K8Z23_20070	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z23_20125	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z23_20130	COG1620	l-lactate permease
K8Z23_20165	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z23_20165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z23_20175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z23_20180	COG5492	domain, Protein
K8Z23_20200	COG2382	esterase
K8Z23_20210	COG2153	protein acetylation
K8Z23_20255	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z23_20270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z23_20290	COG0463	Glycosyl transferase, family 2
K8Z23_20290	COG0457	Tetratricopeptide repeat
K8Z23_20310	COG1216	Glycosyl transferase, family 2
K8Z23_20315	COG0772	Belongs to the SEDS family
K8Z23_20330	COG0564	pseudouridine synthase activity
K8Z23_20340	COG2357	RelA SpoT domain protein
K8Z23_20350	COG4116	CYTH
K8Z23_20355	COG2346	COG2346, Truncated hemoglobins
K8Z23_20370	COG1164	Oligoendopeptidase f
K8Z23_20390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z23_20400	COG0861	Integral membrane protein TerC family
K8Z23_20415	COG4166	transmembrane transport
K8Z23_20420	COG0534	Mate efflux family protein
K8Z23_20425	COG4608	Belongs to the ABC transporter superfamily
K8Z23_20430	COG0444	Belongs to the ABC transporter superfamily
K8Z23_20435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z23_20440	COG0601	transmembrane transport
K8Z23_20445	COG4166	transmembrane transport
K8Z23_20455	COG0180	Tryptophanyl-tRNA synthetase
K8Z23_20465	COG5504	Zn-dependent protease
K8Z23_20470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z23_20475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z23_20490	COG2267	carboxylic ester hydrolase activity
K8Z23_20510	COG0561	phosphatase activity
K8Z23_20525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_20540	COG2996	Protein conserved in bacteria
K8Z23_20560	COG0004	ammonium transporteR
K8Z23_20565	COG0753	catalase activity
K8Z23_20575	COG0367	asparagine synthase
K8Z23_20600	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z23_20660	COG0398	Pfam SNARE associated Golgi protein
K8Z23_20665	COG4903	ComK protein
K8Z23_20680	COG1278	Cold shock
K8Z23_20695	COG2224	Isocitrate lyase
K8Z23_20700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z23_20710	COG3693	PFAM glycoside hydrolase, family 10
K8Z23_20720	COG0840	transmembrane signaling receptor activity
K8Z23_20725	COG0501	Belongs to the peptidase M48B family
K8Z23_20745	COG0745	RESPONSE REGULATOR receiver
K8Z23_20750	COG2205	protein histidine kinase activity
K8Z23_20765	COG2207	Transcriptional regulator
K8Z23_20765	COG3708	Transcriptional regulator
K8Z23_20770	COG1595	DNA-templated transcription, initiation
K8Z23_20780	COG1078	dGTPase activity
K8Z23_20785	COG1408	metallophosphoesterase
K8Z23_20790	COG1073	alpha beta
K8Z23_20820	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z23_20830	COG0095	Lipoate-protein ligase
K8Z23_20835	COG1234	tRNA 3'-trailer cleavage
K8Z23_20845	COG1609	Transcriptional regulator
K8Z23_20870	COG1511	domain protein
K8Z23_20875	COG1309	transcriptional regulator
K8Z23_20900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z23_20915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z23_20920	COG2329	Antibiotic biosynthesis monooxygenase
K8Z23_20925	COG3428	Bacterial PH domain
K8Z23_20930	COG3402	PFAM membrane-flanked domain
K8Z23_20935	COG0697	spore germination
K8Z23_20970	COG3428	Bacterial PH domain
K8Z23_20975	COG3402	PFAM membrane-flanked domain
K8Z23_20985	COG1309	transcriptional regulator
K8Z23_21000	COG4473	ABC transporter
K8Z23_21005	COG1131	(ABC) transporter
K8Z23_21010	COG0537	adenosine 5'-monophosphoramidase activity
K8Z23_21015	COG4980	gas vesicle protein
K8Z23_21040	COG3973	AAA domain
K8Z23_21070	COG1404	Belongs to the peptidase S8 family
K8Z23_21080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z23_21090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z23_21095	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z23_21100	COG3620	sequence-specific DNA binding
K8Z23_21105	COG2140	Oxalate decarboxylase
K8Z23_21130	COG2267	carboxylic ester hydrolase activity
K8Z23_21155	COG0346	lactoylglutathione lyase activity
K8Z23_21160	COG0346	lactoylglutathione lyase activity
K8Z23_21165	COG1280	lysine exporter protein (LysE YggA)
K8Z23_21180	COG4717	serine-type aminopeptidase activity
K8Z23_21185	COG0420	3'-5' exonuclease activity
K8Z23_21205	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z23_21255	COG5002	protein histidine kinase activity
K8Z23_21255	COG2205	protein histidine kinase activity
K8Z23_21255	COG0784	Response regulator, receiver
K8Z23_21260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z23_21265	COG2208	phosphoserine phosphatase activity
K8Z23_21275	COG1191	sigma factor activity
K8Z23_21300	COG3237	CsbD-like
K8Z23_21355	COG2373	Large extracellular alpha-helical protein
K8Z23_21380	COG1959	2 iron, 2 sulfur cluster binding
K8Z23_21390	COG2376	Dihydroxyacetone kinase
K8Z23_21400	COG2376	Dihydroxyacetone kinase
K8Z23_21415	COG1183	phosphatidylcholine synthase activity
K8Z23_21430	COG1309	transcriptional regulator
K8Z23_21435	COG3320	Male sterility
K8Z23_21435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z23_21540	COG0477	Major facilitator Superfamily
K8Z23_21580	COG0305	Participates in initiation and elongation during chromosome replication
K8Z23_21600	COG0513	Belongs to the DEAD box helicase family
K8Z23_21605	COG0494	nUDIX hydrolase
K8Z23_21610	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z23_21615	COG4565	transcriptional regulatory protein
K8Z23_21620	COG3290	protein histidine kinase activity
K8Z23_21680	COG1609	Transcriptional regulator
K8Z23_21685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z23_21685	COG1263	PTS System
K8Z23_21690	COG1621	beta-fructofuranosidase activity
K8Z23_21695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z23_21710	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_21715	COG2252	PERMEase
K8Z23_21725	COG1136	(ABC) transporter
K8Z23_21750	COG1846	Transcriptional regulator
K8Z23_21755	COG2814	Major facilitator Superfamily
K8Z23_21760	COG2205	protein histidine kinase activity
K8Z23_21800	COG0351	phosphomethylpyrimidine kinase
K8Z23_21805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z23_21815	COG2104	thiamine diphosphate biosynthetic process
K8Z23_21820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z23_21825	COG0352	thiamine-phosphate diphosphorylase activity
K8Z23_21830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z23_21835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z23_21840	COG1116	anion transmembrane transporter activity
K8Z23_21845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z23_21865	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z23_21985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z23_21995	COG0581	inorganic phosphate transmembrane transporter activity
K8Z23_22000	COG0573	inorganic phosphate transmembrane transporter activity
K8Z23_22005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z23_22010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z23_22010	COG1918	ferrous iron import across plasma membrane
K8Z23_22015	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z23_22020	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z23_22035	COG0531	amino acid
K8Z23_22040	COG0697	spore germination
K8Z23_22045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z23_22060	COG4990	cell redox homeostasis
K8Z23_22065	COG0833	amino acid
K8Z23_22075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z23_22090	COG0475	glutathione-regulated potassium exporter activity
K8Z23_22090	COG0569	domain protein
K8Z23_22100	COG2153	protein acetylation
K8Z23_22115	COG2252	PERMEase
K8Z23_22120	COG1113	amino acid transport
K8Z23_22135	COG1114	Component of the transport system for branched-chain amino acids
K8Z23_22140	COG3104	oligopeptide transport
K8Z23_22160	COG1476	TRANSCRIPTIONal
K8Z23_22165	COG3584	3D domain protein
K8Z23_22165	COG1388	LysM domain
K8Z23_22170	COG0840	transmembrane signaling receptor activity
K8Z23_22220	COG1063	alcohol dehydrogenase
K8Z23_22250	COG1879	ABC-type sugar transport system periplasmic component
K8Z23_22255	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z23_22295	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z23_22435	COG3331	DNA recombination
K8Z23_22540	COG4974	Belongs to the 'phage' integrase family
K8Z23_22555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z23_22560	COG1609	Transcriptional regulator
K8Z23_22565	COG0477	Major facilitator Superfamily
K8Z23_22570	COG1846	Transcriptional regulator
K8Z23_22575	COG2271	Major facilitator Superfamily
K8Z23_22590	COG0659	secondary active sulfate transmembrane transporter activity
K8Z23_22605	COG5002	protein histidine kinase activity
K8Z23_22610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z23_22615	COG2378	regulation of single-species biofilm formation
K8Z23_22625	COG1595	DNA-templated transcription, initiation
K8Z23_22640	COG0833	amino acid
K8Z23_22645	COG0765	amino acid transport
K8Z23_22650	COG0765	amino acid transport
K8Z23_22655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z23_22660	COG1126	abc transporter atp-binding protein
K8Z23_22665	COG1115	amino acid carrier protein
K8Z23_22670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z23_22675	COG0697	spore germination
K8Z23_22690	COG0366	Alpha amylase catalytic
K8Z23_22695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z23_22695	COG1263	PTS System
K8Z23_22700	COG2188	Transcriptional regulator
K8Z23_22705	COG0531	amino acid
K8Z23_22725	COG0714	Associated with various cellular activities
K8Z23_22730	COG4548	von Willebrand factor, type A
K8Z23_22740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z23_22745	COG0156	8-amino-7-oxononanoate synthase activity
K8Z23_22760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_22765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_22770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_22775	COG3104	oligopeptide transport
K8Z23_22790	COG1620	l-lactate permease
K8Z23_22795	COG1027	Aspartate ammonia-lyase
K8Z23_22800	COG1253	flavin adenine dinucleotide binding
K8Z23_22805	COG0346	lactoylglutathione lyase activity
K8Z23_22810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z23_22815	COG1316	TRANSCRIPTIONal
K8Z23_22820	COG2720	vancomycin resistance protein
K8Z23_22840	COG3227	Zinc metalloprotease (Elastase)
K8Z23_22855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z23_22860	COG2217	Heavy metal translocating P-type atpase
K8Z23_22865	COG0640	Transcriptional regulator
K8Z23_22870	COG0531	amino acid
K8Z23_22885	COG2427	Protein of unknown function (DUF1641)
K8Z23_22890	COG3383	formate dehydrogenase (NAD+) activity
K8Z23_22895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z23_22915	COG5002	protein histidine kinase activity
K8Z23_22925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_22940	COG0281	malic enzyme
K8Z23_22945	COG3493	citrate carrier protein
K8Z23_22950	COG4565	transcriptional regulatory protein
K8Z23_22955	COG3290	protein histidine kinase activity
K8Z23_22965	COG4990	cell redox homeostasis
K8Z23_22980	COG5002	protein histidine kinase activity
K8Z23_22985	COG0745	RESPONSE REGULATOR receiver
K8Z23_22990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z23_23000	COG0395	ABC-type sugar transport system, permease component
K8Z23_23005	COG1175	transmembrane transport
K8Z23_23010	COG3842	ATPase activity
K8Z23_23015	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z23_23040	COG2851	Citrate transporter
K8Z23_23045	COG4565	transcriptional regulatory protein
K8Z23_23050	COG3290	protein histidine kinase activity
K8Z23_23060	COG2268	Band 7 protein
K8Z23_23065	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z23_23075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z23_23090	COG2766	serine protein kinase
K8Z23_23100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z23_23125	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z23_23245	COG0735	belongs to the Fur family
K8Z23_23250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z23_23270	COG4555	ABC transporter
K8Z23_23280	COG0067	glutamate synthase
K8Z23_23280	COG0069	glutamate synthase activity
K8Z23_23280	COG0070	glutamate synthase
K8Z23_23285	COG4129	membrane
K8Z23_23290	COG1132	(ABC) transporter
K8Z23_23315	COG1194	a g-specific adenine glycosylase
K8Z23_23320	COG1988	membrane-bound metal-dependent
K8Z23_23350	COG1090	epimerase
K8Z23_23355	COG1228	amidohydrolase
K8Z23_23375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z23_23390	COG0463	Glycosyl transferase, family 2
K8Z23_23395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z23_23395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z23_23405	COG1216	Glycosyl transferase, family 2
K8Z23_23420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z23_23425	COG1263	PTS System
K8Z23_23425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z23_23455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z23_23460	COG0833	amino acid
K8Z23_23470	COG3829	transcription factor binding
K8Z23_23490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z23_23495	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z23_23515	COG0535	radical SAM domain protein
K8Z23_23525	COG0387	Pfam Sodium calcium exchanger
K8Z23_23530	COG3871	stress protein (general stress protein 26)
K8Z23_23545	COG0586	Pfam SNARE associated Golgi protein
K8Z23_23555	COG0681	Belongs to the peptidase S26 family
K8Z23_23565	COG0697	spore germination
K8Z23_23570	COG2217	Heavy metal translocating P-type atpase
K8Z23_23575	COG1295	ribonuclease BN
K8Z23_23585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z23_23600	COG3853	Toxic anion resistance protein (TelA)
K8Z23_23610	COG0861	Integral membrane protein TerC family
K8Z23_23615	COG2310	stress, protein
K8Z23_23620	COG2310	stress, protein
K8Z23_23625	COG2310	stress, protein
K8Z23_23655	COG2270	Major facilitator Superfamily
K8Z23_23705	COG1116	anion transmembrane transporter activity
K8Z23_23710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z23_23715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z23_23735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z23_23765	COG1263	PTS System
K8Z23_23765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z23_23765	COG2190	(PTS) system
K8Z23_23770	COG0366	Alpha amylase catalytic
K8Z23_23775	COG0277	FAD linked oxidase domain protein
K8Z23_23785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z23_23790	COG0549	Belongs to the carbamate kinase family
K8Z23_23815	COG0840	transmembrane signaling receptor activity
K8Z23_23825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z23_23830	COG0765	amino acid transport
K8Z23_23855	COG2814	Major facilitator Superfamily
K8Z23_23865	COG3541	Predicted nucleotidyltransferase
K8Z23_23885	COG5002	protein histidine kinase activity
K8Z23_23910	COG0166	Belongs to the GPI family
K8Z23_23925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_23930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_23935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_23945	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
K8Z23_23955	COG0450	alkyl hydroperoxide reductase
K8Z23_23970	COG1473	amidohydrolase
K8Z23_23975	COG1757	Na H antiporter
K8Z23_24000	COG4807	Protein conserved in bacteria
K8Z23_24005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z23_24015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z23_24030	COG2309	aminopeptidase activity
K8Z23_24040	COG2076	Multidrug Resistance protein
K8Z23_24045	COG1012	belongs to the aldehyde dehydrogenase family
K8Z23_24055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z23_24060	COG0546	phosphoglycolate phosphatase activity
K8Z23_24065	COG1597	lipid kinase activity
K8Z23_24085	COG4682	membrane
K8Z23_24090	COG1846	Transcriptional regulator
K8Z23_24095	COG0003	Pfam Anion-transporting ATPase
K8Z23_24110	COG1464	Belongs to the NlpA lipoprotein family
K8Z23_24115	COG2011	ABC-type metal ion transport system permease component
K8Z23_24125	COG1335	isochorismatase
K8Z23_24140	COG4851	CamS sex pheromone cAM373 precursor
K8Z23_24150	COG0210	DNA helicase
K8Z23_24175	COG0151	Belongs to the GarS family
K8Z23_24185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z23_24195	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z23_24210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z23_24220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z23_24225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z23_24230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z23_24255	COG0697	spore germination
K8Z23_24275	COG0745	RESPONSE REGULATOR receiver
K8Z23_24280	COG2205	protein histidine kinase activity
K8Z23_24325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z23_24345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z23_24370	COG5002	protein histidine kinase activity
K8Z23_24380	COG2252	PERMEase
K8Z23_24400	COG1266	CAAX protease self-immunity
K8Z23_24415	COG0488	(ABC) transporter
K8Z23_24425	COG0456	acetyltransferase
K8Z23_24430	COG1214	PFAM Peptidase M22, glycoprotease
K8Z23_24435	COG0802	atpase or kinase
K8Z23_24535	COG2183	response to ionizing radiation
K8Z23_24540	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z23_24545	COG0864	Transcriptional regulator
K8Z23_24550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z23_24555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z23_24565	COG0705	Rhomboid family
K8Z23_24570	COG4294	response to UV
K8Z23_24580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z23_24590	COG2814	Major facilitator Superfamily
K8Z23_24595	COG0531	amino acid
K8Z23_24605	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z23_24610	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z23_24640	COG0561	phosphatase activity
K8Z23_24645	COG4608	Belongs to the ABC transporter superfamily
K8Z23_24650	COG0444	Belongs to the ABC transporter superfamily
K8Z23_24655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z23_24660	COG0601	transmembrane transport
K8Z23_24665	COG0747	negative chemotaxis
K8Z23_24675	COG0488	(ABC) transporter
K8Z23_24705	COG5298	Protein conserved in bacteria
K8Z23_24720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z23_24730	COG1609	Transcriptional regulator
K8Z23_24740	COG0204	Acyl-transferase
K8Z23_24755	COG0697	spore germination
K8Z23_24770	COG1910	domain protein
K8Z23_24775	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z23_24780	COG4149	molybdate abc transporter
K8Z23_24795	COG0656	L-ascorbic acid biosynthetic process
K8Z23_24800	COG4166	transmembrane transport
K8Z23_24805	COG4166	transmembrane transport
K8Z23_24820	COG4166	transmembrane transport
K8Z23_24825	COG4608	Belongs to the ABC transporter superfamily
K8Z23_24830	COG0444	Belongs to the ABC transporter superfamily
K8Z23_24835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z23_24840	COG0601	transmembrane transport
K8Z23_24860	COG2814	Major facilitator Superfamily
K8Z23_24870	COG2271	Major facilitator Superfamily
K8Z23_24875	COG0277	FAD linked oxidase domain protein
K8Z23_24885	COG0604	alcohol dehydrogenase
K8Z23_24890	COG1464	Belongs to the NlpA lipoprotein family
K8Z23_24895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z23_24900	COG2011	ABC-type metal ion transport system permease component
K8Z23_24905	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z23_24940	COG4856	YbbR-like protein
K8Z23_24945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z23_25025	COG0726	polysaccharide deacetylase
K8Z23_25030	COG2194	sulfuric ester hydrolase activity
K8Z23_25040	COG0489	protein tyrosine kinase activity
K8Z23_25045	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z23_25070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z23_25105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z23_25115	COG0024	Methionine aminopeptidase
K8Z23_25125	COG0201	protein transport
K8Z23_25185	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z23_25225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K8Z23_25230	COG0051	transcription antitermination factor activity, RNA binding
K8Z23_25250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z23_25255	COG1358	cellular component organization or biogenesis
K8Z23_25260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K8Z23_25270	COG2813	Specifically methylates the guanine in position
K8Z23_25290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z23_25295	COG0250	Participates in transcription elongation, termination and antitermination
K8Z23_25300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z23_25315	COG3688	RNA-binding protein containing a PIN domain
K8Z23_25320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z23_25335	COG1045	serine acetyltransferase
K8Z23_25355	COG4956	integral membrane protein (PIN domain superfamily)
K8Z23_25365	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z23_25370	COG0542	response to heat
K8Z23_25380	COG3880	PFAM UvrB UvrC protein
K8Z23_25470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z23_25475	COG1396	sequence-specific DNA binding
K8Z23_25480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z23_25485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z23_25490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z23_25495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z23_25500	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z23_25505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z23_25510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z23_25525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z23_25530	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z23_25540	COG2208	phosphoserine phosphatase activity
K8Z23_25555	COG1098	S1 RNA binding domain
K8Z23_25575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z23_25580	COG3956	TIGRFAM MazG family protein
K8Z23_25585	COG2244	polysaccharide biosynthetic process
K8Z23_25590	COG2002	toxin-antitoxin pair type II binding
K8Z23_25595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z23_25625	COG0251	oxidation-reduction process
K8Z23_25630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z23_25645	COG4466	Protein conserved in bacteria
K8Z23_25665	COG0084	hydrolase, TatD family'
K8Z23_25675	COG2002	toxin-antitoxin pair type II binding
K8Z23_25680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z23_25690	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z23_25700	COG1774	PSP1 C-terminal conserved region
K8Z23_25705	COG0470	DNA polymerase III
K8Z23_25715	COG1982	Orn Lys Arg decarboxylase major
K8Z23_25775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z23_25785	COG0590	tRNA wobble adenosine to inosine editing
K8Z23_25790	COG1335	isochorismatase
K8Z23_25795	COG1428	Deoxynucleoside kinase
K8Z23_25800	COG1428	Deoxynucleoside kinase
K8Z23_25830	COG1686	Belongs to the peptidase S11 family
K8Z23_25835	COG0516	GMP reductase activity
K8Z23_25835	COG0517	IMP dehydrogenase activity
K8Z23_25870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z23_25875	COG0187	DNA topoisomerase II activity
K8Z23_25885	COG2501	S4 domain
K8Z23_25890	COG0592	DNA-directed DNA polymerase activity
K8Z23_25900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z23_25915	COG1847	R3H domain protein
K8Z23_25940	COG1192	Involved in chromosome partitioning
K8Z23_25945	COG1475	DNA binding
K8Z23_25955	COG0668	transmembrane transport
K8Z23_25960	COG4481	Protein conserved in bacteria
K8Z23_25965	COG0012	GTP binding
K8Z23_25975	COG0629	single-stranded DNA binding
K8Z23_25985	COG4241	membrane
K8Z23_25990	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z23_26000	COG0305	Participates in initiation and elongation during chromosome replication
K8Z23_26030	COG0745	RESPONSE REGULATOR receiver
K8Z23_26035	COG5002	protein histidine kinase activity
K8Z23_26045	COG4853	Protein conserved in bacteria
K8Z23_26050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z23_26055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z23_26070	COG5002	protein histidine kinase activity
K8Z23_26085	COG1164	Oligoendopeptidase f
K8Z23_26105	COG1272	protein, Hemolysin III
K8Z23_26110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z23_26135	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
K8Z23_26140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z23_26145	COG2814	Major facilitator Superfamily
K8Z23_26150	COG3275	phosphorelay sensor kinase activity
K8Z23_26170	COG0628	permease
K8Z23_26175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z23_26175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z23_26180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z23_26185	COG1309	transcriptional regulator
K8Z23_26190	COG0488	(ABC) transporter
K8Z23_26195	COG1309	transcriptional regulator
K8Z23_26205	COG0463	Glycosyl transferase, family 2
K8Z23_26220	COG1216	Glycosyl transferase, family 2
K8Z23_26235	COG1216	Glycosyl transferase, family 2
K8Z23_26240	COG1607	acyl-coa hydrolase
K8Z23_26250	COG0840	transmembrane signaling receptor activity
K8Z23_26265	COG0438	transferase activity, transferring glycosyl groups
K8Z23_26275	COG0477	Major facilitator Superfamily
K8Z23_26280	COG3279	Response regulator of the LytR AlgR family
K8Z23_26285	COG1966	Carbon starvation protein
K8Z23_26290	COG2879	small protein
K8Z23_26295	COG3706	GGDEF domain
K8Z23_26300	COG0351	phosphomethylpyrimidine kinase
K8Z23_26305	COG2203	Gaf domain
K8Z23_26305	COG4585	Histidine kinase
K8Z23_26310	COG2197	response regulator
K8Z23_26320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z23_26325	COG1011	Hydrolase
K8Z23_26330	COG2873	o-acetylhomoserine
K8Z23_26340	COG0460	homoserine dehydrogenase
K8Z23_26350	COG1609	Transcriptional regulator
K8Z23_26355	COG2755	lipolytic protein G-D-S-L family
K8Z23_26360	COG1131	(ABC) transporter
K8Z23_26365	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K8Z23_26375	COG2814	Major facilitator Superfamily
K8Z23_26380	COG0561	phosphatase activity
K8Z23_26385	COG2233	PERMEase
K8Z23_26390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z23_26400	COG2363	Small membrane protein
K8Z23_26410	COG3773	Cell wall hydrolase
K8Z23_26425	COG0280	phosphate acetyltransferase
K8Z23_26445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_26450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z23_26455	COG1120	ATPase activity
K8Z23_26460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z23_26465	COG1078	dGTPase activity
K8Z23_26475	COG1994	Peptidase M50
K8Z23_26485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z23_26490	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z23_26495	COG0789	Transcriptional regulator
K8Z23_26500	COG2814	Major facilitator Superfamily
K8Z23_26525	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z23_26530	COG4506	Protein conserved in bacteria
K8Z23_26540	COG1595	DNA-templated transcription, initiation
K8Z23_26560	COG2234	aminopeptidase activity
K8Z23_26570	COG0024	Methionine aminopeptidase
K8Z23_26575	COG1131	(ABC) transporter
K8Z23_26580	COG0842	Transport permease protein
K8Z23_26585	COG4585	Histidine kinase
K8Z23_26590	COG2197	response regulator
K8Z23_26595	COG3227	Zinc metalloprotease (Elastase)
K8Z23_26610	COG5001	Diguanylate cyclase
K8Z23_26610	COG3300	MHYT domain
K8Z23_26620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z23_26625	COG0247	lactate metabolic process
K8Z23_26625	COG2181	nitrate reductase activity
K8Z23_26630	COG0183	Belongs to the thiolase family
K8Z23_26635	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z23_26640	COG1960	acyl-CoA dehydrogenase activity
K8Z23_26645	COG1960	acyl-CoA dehydrogenase activity
K8Z23_26665	COG4821	SIS domain
K8Z23_26685	COG1494	fructose-1,6-bisphosphatase
K8Z23_26690	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z23_26725	COG0009	L-threonylcarbamoyladenylate synthase
K8Z23_26740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z23_26745	COG2259	Doxx family
K8Z23_26750	COG2190	(PTS) system
K8Z23_26760	COG0698	ribose 5-phosphate isomerase
K8Z23_26795	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z23_26845	COG5001	Diguanylate cyclase
K8Z23_26845	COG3300	MHYT domain
K8Z23_26860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z23_26880	COG0839	Belongs to the complex I subunit 6 family
K8Z23_26890	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z23_26895	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z23_26900	COG1007	ATP synthesis coupled electron transport
K8Z23_26905	COG4836	Membrane
K8Z23_26920	COG2385	sporulation resulting in formation of a cellular spore
K8Z23_26925	COG3279	Response regulator of the LytR AlgR family
K8Z23_26940	COG0739	heme binding
K8Z23_26950	COG1609	Transcriptional regulator
K8Z23_26965	COG0489	protein tyrosine kinase activity
K8Z23_26970	COG3944	biosynthesis protein
K8Z23_26975	COG0489	protein tyrosine kinase activity
K8Z23_26980	COG4464	protein tyrosine phosphatase activity
K8Z23_26995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z23_27000	COG1215	transferase activity, transferring glycosyl groups
K8Z23_27025	COG1215	transferase activity, transferring glycosyl groups
K8Z23_27035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z23_27045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z23_27050	COG1316	TRANSCRIPTIONal
K8Z23_27060	COG0745	RESPONSE REGULATOR receiver
K8Z23_27065	COG5002	protein histidine kinase activity
K8Z23_27090	COG1136	(ABC) transporter
K8Z23_27095	COG0577	efflux transmembrane transporter activity
K8Z23_27135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z23_27140	COG4715	Zinc finger, swim domain protein
K8Z23_27165	COG1388	LysM domain
K8Z23_27165	COG3584	3D domain protein
K8Z23_27170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z23_27175	COG1215	transferase activity, transferring glycosyl groups
K8Z23_27190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z23_27195	COG0791	NLP P60 protein
K8Z23_27195	COG1388	LysM domain
K8Z23_27205	COG1368	sulfuric ester hydrolase activity
K8Z23_27215	COG2389	metal-binding protein
K8Z23_27225	COG1620	l-lactate permease
K8Z23_27235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z23_27240	COG1294	oxidase, subunit
K8Z23_27245	COG1271	oxidase subunit
K8Z23_27260	COG0583	DNA-binding transcription factor activity
K8Z23_27265	COG1511	domain protein
K8Z23_27280	COG1301	dicarboxylic acid transport
K8Z23_27285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z23_27295	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z23_27305	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K8Z23_27315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z23_27320	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z23_27325	COG1486	melibiose metabolic process
K8Z23_27345	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z23_27345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z23_27355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z23_27360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z23_27365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z23_27370	COG1316	TRANSCRIPTIONal
K8Z23_27375	COG1739	Uncharacterized protein family UPF0029
K8Z23_27380	COG1307	EDD domain protein, DegV family
K8Z23_27385	COG1733	regulation of RNA biosynthetic process
K8Z23_27390	COG0791	NLP P60 protein
K8Z23_27390	COG1388	LysM domain
K8Z23_27395	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z23_27400	COG1040	competence protein
K8Z23_27405	COG1278	Cold shock
K8Z23_27410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z23_27450	COG1131	(ABC) transporter
K8Z23_27475	COG2884	Cell division ATP-binding protein ftsE
K8Z23_27480	COG2177	Part of the ABC transporter FtsEX involved in
K8Z23_27485	COG3409	Peptidoglycan-binding domain 1 protein
K8Z23_27485	COG0793	Belongs to the peptidase S41A family
K8Z23_27490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z23_27495	COG1132	(ABC) transporter
K8Z23_27505	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z23_27515	COG0583	DNA-binding transcription factor activity
K8Z23_27535	COG0789	Transcriptional regulator
K8Z23_27550	COG0556	nucleotide-excision repair
K8Z23_27555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z23_27565	COG1950	PFAM Membrane protein of
K8Z23_27585	COG0110	maltose O-acetyltransferase activity
K8Z23_27590	COG0457	Tetratricopeptide repeat
K8Z23_27595	COG0492	ferredoxin-NADP+ reductase activity
K8Z23_27605	COG1051	belongs to the nudix hydrolase family
K8Z23_27615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z23_27625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z23_27635	COG2323	membrane
K8Z23_27650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z23_27715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z23_27730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z23_27765	COG1346	cytolysis
K8Z23_27770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z23_27775	COG1647	Serine aminopeptidase, S33
K8Z23_27780	COG0582	viral genome integration into host DNA
K8Z23_27795	COG1396	sequence-specific DNA binding
K8Z23_27880	COG0582	viral genome integration into host DNA
K8Z23_27980	COG1482	cell wall glycoprotein biosynthetic process
K8Z23_27985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z23_27985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z23_27985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z23_27990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z23_27990	COG3711	transcriptional antiterminator
K8Z23_27995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z23_28005	COG1309	transcriptional regulator
K8Z23_28025	COG0456	acetyltransferase
K8Z23_28035	COG0456	acetyltransferase
K8Z23_28060	COG1131	(ABC) transporter
K8Z23_28065	COG2205	protein histidine kinase activity
K8Z23_28070	COG0745	RESPONSE REGULATOR receiver
K8Z23_28140	COG2814	Major facilitator Superfamily
K8Z23_28325	COG1674	ftsk spoiiie
K8Z23_28440	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z23_28440	COG3409	Peptidoglycan-binding domain 1 protein
K8Z23_28600	COG0457	Tetratricopeptide repeat
K8Z23_28665	COG3437	response regulator, receiver
K8Z23_28725	COG2801	Transposase and inactivated derivatives
K8Z23_28765	COG4974	Belongs to the 'phage' integrase family
K8Z23_28785	COG4166	transmembrane transport
K8Z23_28820	COG2002	toxin-antitoxin pair type II binding
K8Z23_28830	COG0776	regulation of translation
K8Z23_28835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z23_28860	COG0457	Tetratricopeptide repeat
K8Z23_28890	COG0697	spore germination
K8Z23_28895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K8Z23_28905	COG2801	Transposase and inactivated derivatives
K8Z23_28915	COG3654	unkown
K8Z23_28925	COG2801	Transposase and inactivated derivatives
K8Z23_28965	COG3335	DDE superfamily endonuclease
K8Z23_28990	COG3397	chitin binding
K8Z23_29000	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z23_29105	COG2002	toxin-antitoxin pair type II binding
K8Z23_29325	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z23_29360	COG2002	toxin-antitoxin pair type II binding
K8Z23_29370	COG0776	regulation of translation
K8Z23_29375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z23_29400	COG0457	Tetratricopeptide repeat
K8Z23_29430	COG1131	(ABC) transporter
K8Z23_29450	COG2311	Membrane
K8Z23_29475	COG3344	reverse transcriptase
K8Z23_29725	COG3344	reverse transcriptase
K8Z23_29945	COG0457	Tetratricopeptide repeat
K8Z23_29965	COG0657	acetylesterase activity
K8Z23_29980	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z23_29990	COG0840	transmembrane signaling receptor activity
K8Z23_30000	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z23_30100	COG4974	Belongs to the 'phage' integrase family
K8Z23_30140	COG0791	NLP P60 protein
K8Z23_30140	COG0741	lytic transglycosylase activity
K8Z23_30315	COG1923	regulation of RNA biosynthetic process
K8Z23_30325	COG0457	Tetratricopeptide repeat
K8Z23_30540	COG3646	Phage regulatory protein
K8Z23_30585	COG3611	Membrane attachment protein
K8Z23_30600	COG4824	toxin secretion phage lysis holin
K8Z23_30750	COG3331	DNA recombination