locus-tag	class	description
K8Z41_00005	COG1802	Transcriptional regulator
K8Z41_00005	COG4626	Terminase
K8Z41_00015	COG0740	serine-type endopeptidase activity
K8Z41_00080	COG4824	toxin secretion phage lysis holin
K8Z41_00085	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_00085	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_00085	COG1388	LysM domain
K8Z41_00140	COG1683	Conserved Protein
K8Z41_00155	COG3708	Transcriptional regulator
K8Z41_00170	COG1252	NADH dehydrogenase
K8Z41_00185	COG3584	3D domain protein
K8Z41_00200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K8Z41_00205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z41_00210	COG1268	BioY protein
K8Z41_00220	COG2050	protein possibly involved in aromatic compounds catabolism
K8Z41_00245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z41_00250	COG5018	Exonuclease
K8Z41_00270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K8Z41_00280	COG2267	carboxylic ester hydrolase activity
K8Z41_00285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z41_00290	COG1522	sequence-specific DNA binding
K8Z41_00295	COG0436	Aminotransferase
K8Z41_00300	COG1098	S1 RNA binding domain
K8Z41_00305	COG2155	Conserved Protein
K8Z41_00320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z41_00325	COG1285	pathogenesis
K8Z41_00360	COG0544	peptidyl-prolyl cis-trans isomerase activity
K8Z41_00480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K8Z41_00490	COG0058	SHG alpha-glucan phosphorylase activity
K8Z41_00520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K8Z41_00525	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z41_00530	COG1169	isochorismate synthase
K8Z41_00540	COG0596	Alpha beta hydrolase
K8Z41_00545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K8Z41_00570	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z41_00590	COG3964	amidohydrolase
K8Z41_00610	COG2188	Transcriptional regulator
K8Z41_00640	COG0577	efflux transmembrane transporter activity
K8Z41_00645	COG1136	(ABC) transporter
K8Z41_00650	COG0577	efflux transmembrane transporter activity
K8Z41_00655	COG0577	efflux transmembrane transporter activity
K8Z41_00660	COG2205	protein histidine kinase activity
K8Z41_00665	COG0745	RESPONSE REGULATOR receiver
K8Z41_00670	COG0640	Transcriptional regulator
K8Z41_00675	COG5658	integral membrane protein
K8Z41_00685	COG3708	Transcriptional regulator
K8Z41_00685	COG2207	Transcriptional regulator
K8Z41_00690	COG1136	(ABC) transporter
K8Z41_00695	COG0577	efflux transmembrane transporter activity
K8Z41_00705	COG0586	Pfam SNARE associated Golgi protein
K8Z41_00730	COG1597	lipid kinase activity
K8Z41_00735	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z41_00760	COG0745	RESPONSE REGULATOR receiver
K8Z41_00765	COG5002	protein histidine kinase activity
K8Z41_00795	COG1842	Phage shock protein A
K8Z41_00815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_00830	COG1294	oxidase, subunit
K8Z41_00835	COG1271	oxidase subunit
K8Z41_00840	COG0288	reversible hydration of carbon dioxide
K8Z41_00850	COG1854	S-ribosylhomocysteine lyase activity
K8Z41_00880	COG0494	nUDIX hydrolase
K8Z41_00905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z41_00910	COG1116	anion transmembrane transporter activity
K8Z41_00915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z41_00940	COG1368	sulfuric ester hydrolase activity
K8Z41_00945	COG2267	carboxylic ester hydrolase activity
K8Z41_00950	COG3852	Histidine kinase
K8Z41_00955	COG5002	protein histidine kinase activity
K8Z41_00970	COG1349	DNA-binding transcription factor activity
K8Z41_01015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_01035	COG0438	transferase activity, transferring glycosyl groups
K8Z41_01040	COG0671	phosphoesterase, PA-phosphatase related
K8Z41_01045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K8Z41_01050	COG2267	carboxylic ester hydrolase activity
K8Z41_01070	COG1794	racemase activity, acting on amino acids and derivatives
K8Z41_01075	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
K8Z41_01080	COG1242	4 iron, 4 sulfur cluster binding
K8Z41_01100	COG1136	(ABC) transporter
K8Z41_01110	COG0582	viral genome integration into host DNA
K8Z41_01115	COG0490	domain, Protein
K8Z41_01120	COG0475	glutathione-regulated potassium exporter activity
K8Z41_01125	COG2814	Major facilitator Superfamily
K8Z41_01170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K8Z41_01180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z41_01200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z41_01205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z41_01215	COG0303	'Molybdopterin
K8Z41_01220	COG1763	Mo-molybdopterin cofactor biosynthetic process
K8Z41_01225	COG0314	molybdopterin synthase activity
K8Z41_01250	COG1329	Transcriptional regulator
K8Z41_01270	COG3832	glyoxalase III activity
K8Z41_01280	COG2814	Major facilitator Superfamily
K8Z41_01285	COG2081	HI0933 family
K8Z41_01290	COG2244	polysaccharide biosynthetic process
K8Z41_01295	COG1187	pseudouridine synthase activity
K8Z41_01300	COG1349	DNA-binding transcription factor activity
K8Z41_01305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z41_01315	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z41_01320	COG0510	thiamine kinase activity
K8Z41_01335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_01345	COG1363	Peptidase, m42
K8Z41_01350	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K8Z41_01355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z41_01365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z41_01380	COG1674	ftsk spoiiie
K8Z41_01395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_01410	COG2309	aminopeptidase activity
K8Z41_01420	COG3118	belongs to the thioredoxin family
K8Z41_01425	COG4851	CamS sex pheromone cAM373 precursor
K8Z41_01430	COG1605	Chorismate mutase
K8Z41_01430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z41_01435	COG1609	Transcriptional regulator
K8Z41_01470	COG3279	Response regulator of the LytR AlgR family
K8Z41_01490	COG0745	RESPONSE REGULATOR receiver
K8Z41_01490	COG2972	Histidine kinase
K8Z41_01495	COG0666	response to abiotic stimulus
K8Z41_01505	COG0745	RESPONSE REGULATOR receiver
K8Z41_01520	COG0123	including yeast histone deacetylase and acetoin utilization protein
K8Z41_01525	COG0517	IMP dehydrogenase activity
K8Z41_01530	COG0454	-acetyltransferase
K8Z41_01535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z41_01540	COG0110	maltose O-acetyltransferase activity
K8Z41_01550	COG1595	DNA-templated transcription, initiation
K8Z41_01600	COG0626	cystathionine gamma-synthase activity
K8Z41_01605	COG1956	GAF domain-containing protein
K8Z41_01610	COG1309	transcriptional regulator
K8Z41_01615	COG0697	spore germination
K8Z41_01620	COG0583	DNA-binding transcription factor activity
K8Z41_01630	COG1104	cysteine desulfurase activity
K8Z41_01645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z41_01655	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K8Z41_01670	COG3874	Sporulation protein YtfJ
K8Z41_01675	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K8Z41_01680	COG0827	DNA restriction-modification system
K8Z41_01705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_01755	COG0589	response to stress
K8Z41_01760	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_01775	COG0662	Cupin 2, conserved barrel domain protein
K8Z41_01815	COG0006	proline dipeptidase activity
K8Z41_01830	COG4109	DRTGG domain
K8Z41_01845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K8Z41_01860	COG0587	DNA-directed DNA polymerase activity
K8Z41_01865	COG0281	malic enzyme
K8Z41_01870	COG1725	Transcriptional regulator
K8Z41_01895	COG3030	protein affecting phage T7 exclusion by the F plasmid
K8Z41_01900	COG0628	permease
K8Z41_01910	COG0372	Belongs to the citrate synthase family
K8Z41_01915	COG0538	isocitrate dehydrogenase activity
K8Z41_01935	COG0745	RESPONSE REGULATOR receiver
K8Z41_01940	COG5002	protein histidine kinase activity
K8Z41_01945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z41_01945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z41_01955	COG1971	Probably functions as a manganese efflux pump
K8Z41_01965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z41_01970	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
K8Z41_01980	COG3611	Membrane attachment protein
K8Z41_01985	COG1484	DNA-dependent DNA replication
K8Z41_02000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z41_02025	COG1363	Peptidase, m42
K8Z41_02030	COG1309	transcriptional regulator
K8Z41_02035	COG1566	PFAM secretion protein HlyD family protein
K8Z41_02040	COG2814	Major facilitator Superfamily
K8Z41_02060	COG1418	mRNA catabolic process
K8Z41_02070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z41_02115	COG1286	toxin biosynthetic process
K8Z41_02120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z41_02120	COG1796	DNA polymerase
K8Z41_02130	COG1187	pseudouridine synthase activity
K8Z41_02135	COG1114	Component of the transport system for branched-chain amino acids
K8Z41_02140	COG5386	Cell surface protein
K8Z41_02150	COG5386	Cell surface protein
K8Z41_02165	COG1120	ATPase activity
K8Z41_02170	COG4509	Sortase family
K8Z41_02180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K8Z41_02185	COG4895	conserved protein (DUF2196)
K8Z41_02195	COG0745	RESPONSE REGULATOR receiver
K8Z41_02200	COG2205	protein histidine kinase activity
K8Z41_02205	COG1131	(ABC) transporter
K8Z41_02235	COG2318	DinB family
K8Z41_02260	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_02265	COG1309	transcriptional regulator
K8Z41_02270	COG1024	Enoyl-CoA hydratase
K8Z41_02275	COG2086	electron transfer activity
K8Z41_02280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K8Z41_02285	COG3118	belongs to the thioredoxin family
K8Z41_02295	COG1719	4-vinyl reductase, 4VR
K8Z41_02300	COG2009	succinate dehydrogenase
K8Z41_02305	COG1053	succinate dehydrogenase
K8Z41_02310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K8Z41_02315	COG0824	Thioesterase
K8Z41_02320	COG1876	peptidase activity
K8Z41_02325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z41_02330	COG1360	Flagellar Motor Protein
K8Z41_02335	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
K8Z41_02340	COG4152	abc transporter atp-binding protein
K8Z41_02345	COG1668	transmembrane transport
K8Z41_02350	COG1959	2 iron, 2 sulfur cluster binding
K8Z41_02360	COG0697	spore germination
K8Z41_02365	COG1396	sequence-specific DNA binding
K8Z41_02370	COG1983	PspC domain protein
K8Z41_02375	COG0402	S-adenosylhomocysteine deaminase activity
K8Z41_02380	COG2233	PERMEase
K8Z41_02385	COG2197	response regulator
K8Z41_02405	COG5401	PFAM Sporulation and spore germination
K8Z41_02420	COG0622	Phosphoesterase
K8Z41_02465	COG0470	DNA polymerase III
K8Z41_02465	COG1067	ATP-dependent peptidase activity
K8Z41_02480	COG1764	response to oxidative stress
K8Z41_02485	COG1846	Transcriptional regulator
K8Z41_02495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z41_02505	COG1587	Uroporphyrinogen-III synthase
K8Z41_02510	COG0113	porphobilinogen synthase activity
K8Z41_02520	COG1388	LysM domain
K8Z41_02535	COG0285	dihydrofolate synthase activity
K8Z41_02555	COG1077	Cell shape determining protein MreB Mrl
K8Z41_02575	COG2894	cell division
K8Z41_02580	COG0739	heme binding
K8Z41_02585	COG1994	Peptidase M50
K8Z41_02590	COG1530	ribonuclease E activity
K8Z41_02600	COG2868	ribosomal protein
K8Z41_02610	COG3290	protein histidine kinase activity
K8Z41_02620	COG0745	RESPONSE REGULATOR receiver
K8Z41_02625	COG5002	protein histidine kinase activity
K8Z41_02630	COG1136	(ABC) transporter
K8Z41_02635	COG0577	efflux transmembrane transporter activity
K8Z41_02640	COG0577	efflux transmembrane transporter activity
K8Z41_02645	COG0077	Prephenate dehydratase
K8Z41_02650	COG2258	MOSC domain
K8Z41_02655	COG1827	regulation of RNA biosynthetic process
K8Z41_02660	COG1104	cysteine desulfurase activity
K8Z41_02665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K8Z41_02670	COG0157	Belongs to the NadC ModD family
K8Z41_02700	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K8Z41_02730	COG1862	Preprotein translocase
K8Z41_02740	COG2323	membrane
K8Z41_02745	COG2244	polysaccharide biosynthetic process
K8Z41_02755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z41_02755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K8Z41_02760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z41_02765	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K8Z41_02765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K8Z41_02775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z41_02800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K8Z41_02810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K8Z41_02815	COG1959	2 iron, 2 sulfur cluster binding
K8Z41_02820	COG1104	cysteine desulfurase activity
K8Z41_02835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z41_02855	COG0628	permease
K8Z41_02885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K8Z41_02890	COG4122	O-methyltransferase activity
K8Z41_02895	COG0826	peptidase U32
K8Z41_02900	COG0826	peptidase U32
K8Z41_02920	COG0768	penicillin binding
K8Z41_02945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z41_02950	COG0626	cystathionine gamma-synthase activity
K8Z41_02955	COG1454	alcohol dehydrogenase
K8Z41_02955	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_02965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z41_03005	COG2259	Doxx family
K8Z41_03010	COG2514	catechol 2,3-dioxygenase activity
K8Z41_03020	COG3186	Phenylalanine-4-hydroxylase
K8Z41_03075	COG2267	carboxylic ester hydrolase activity
K8Z41_03085	COG1785	Belongs to the alkaline phosphatase family
K8Z41_03095	COG2357	RelA SpoT domain protein
K8Z41_03100	COG0778	Nitroreductase
K8Z41_03110	COG1595	DNA-templated transcription, initiation
K8Z41_03135	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
K8Z41_03140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K8Z41_03150	COG1534	Rna-binding protein
K8Z41_03160	COG1713	HD superfamily hydrolase involved in NAD metabolism
K8Z41_03165	COG0799	negative regulation of ribosome biogenesis
K8Z41_03170	COG2226	methyltransferase
K8Z41_03175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z41_03180	COG1555	photosystem II stabilization
K8Z41_03180	COG1596	polysaccharide export
K8Z41_03185	COG2131	deaminase
K8Z41_03190	COG0658	competence protein
K8Z41_03190	COG2333	competence protein COMEC
K8Z41_03200	COG1466	dna polymerase III delta subunit
K8Z41_03225	COG1733	regulation of RNA biosynthetic process
K8Z41_03230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z41_03260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K8Z41_03265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K8Z41_03270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K8Z41_03275	COG1610	YqeY-like protein
K8Z41_03290	COG1702	phosphate starvation-inducible protein PhoH
K8Z41_03295	COG1480	7TM receptor with intracellular HD hydrolase
K8Z41_03305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K8Z41_03310	COG0295	cytidine deaminase activity
K8Z41_03315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K8Z41_03330	COG0517	IMP dehydrogenase activity
K8Z41_03345	COG0358	DNA primase activity
K8Z41_03350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K8Z41_03360	COG2384	SAM-dependent methyltransferase
K8Z41_03365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K8Z41_03395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_03400	COG1121	(ABC) transporter
K8Z41_03405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K8Z41_03410	COG0735	belongs to the Fur family
K8Z41_03425	COG5521	maltodextrose utilization protein MalA
K8Z41_03435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z41_03440	COG0477	Major facilitator Superfamily
K8Z41_03445	COG0768	penicillin binding
K8Z41_03450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z41_03455	COG0573	inorganic phosphate transmembrane transporter activity
K8Z41_03460	COG0573	inorganic phosphate transmembrane transporter activity
K8Z41_03470	COG0704	Plays a role in the regulation of phosphate uptake
K8Z41_03475	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z41_03480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K8Z41_03485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K8Z41_03490	COG4483	Protein conserved in bacteria
K8Z41_03495	COG1940	carbohydrate kinase activity
K8Z41_03505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_03525	COG0626	cystathionine gamma-synthase activity
K8Z41_03530	COG0626	cystathionine gamma-synthase activity
K8Z41_03535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K8Z41_03535	COG0646	methionine synthase
K8Z41_03540	COG1410	methionine synthase
K8Z41_03540	COG0646	methionine synthase
K8Z41_03595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K8Z41_03600	COG1459	type II secretion system
K8Z41_03665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z41_03695	COG1725	Transcriptional regulator
K8Z41_03700	COG1131	(ABC) transporter
K8Z41_03730	COG2076	Multidrug Resistance protein
K8Z41_03735	COG2076	Multidrug Resistance protein
K8Z41_03745	COG1609	Transcriptional regulator
K8Z41_03755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z41_03795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K8Z41_03805	COG3872	metal-dependent enzyme
K8Z41_03820	COG0006	proline dipeptidase activity
K8Z41_03845	COG3854	ATPases associated with a variety of cellular activities
K8Z41_03890	COG0511	ligase activity, forming carbon-carbon bonds
K8Z41_03895	COG0439	Biotin carboxylase
K8Z41_03900	COG1302	Protein conserved in bacteria
K8Z41_03925	COG0142	geranyltranstransferase activity
K8Z41_03935	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
K8Z41_03945	COG0497	DNA recombination
K8Z41_03950	COG0750	zinc metalloprotease
K8Z41_03965	COG3093	addiction module antidote protein HigA
K8Z41_03970	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z41_03980	COG3290	protein histidine kinase activity
K8Z41_03980	COG3829	transcription factor binding
K8Z41_03985	COG0280	phosphate acetyltransferase
K8Z41_04000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z41_04005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z41_04010	COG0022	dehydrogenase e1 component
K8Z41_04015	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z41_04020	COG0772	Belongs to the SEDS family
K8Z41_04025	COG2323	membrane
K8Z41_04045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z41_04050	COG0765	amino acid transport
K8Z41_04055	COG1126	abc transporter atp-binding protein
K8Z41_04060	COG4129	membrane
K8Z41_04065	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z41_04080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_04085	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z41_04095	COG1285	pathogenesis
K8Z41_04130	COG1760	l-serine dehydratase
K8Z41_04135	COG1760	l-serine dehydratase
K8Z41_04140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z41_04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_04150	COG0300	oxidoreductase activity
K8Z41_04195	COG1522	sequence-specific DNA binding
K8Z41_04205	COG0737	Belongs to the 5'-nucleotidase family
K8Z41_04210	COG1757	Na H antiporter
K8Z41_04220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z41_04235	COG1073	alpha beta
K8Z41_04235	COG2226	methyltransferase
K8Z41_04265	COG0307	riboflavin synthase, alpha
K8Z41_04270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z41_04270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z41_04285	COG1073	alpha beta
K8Z41_04290	COG0456	acetyltransferase
K8Z41_04295	COG1609	Transcriptional regulator
K8Z41_04300	COG2056	Na+-H+ antiporter family
K8Z41_04305	COG0596	Alpha beta hydrolase
K8Z41_04315	COG0737	Belongs to the 5'-nucleotidase family
K8Z41_04315	COG1525	nuclease
K8Z41_04315	COG4085	toxin activity
K8Z41_04325	COG0456	acetyltransferase
K8Z41_04325	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z41_04330	COG0656	L-ascorbic acid biosynthetic process
K8Z41_04335	COG0667	Aldo Keto reductase
K8Z41_04355	COG1300	Membrane
K8Z41_04360	COG0735	belongs to the Fur family
K8Z41_04370	COG4974	Belongs to the 'phage' integrase family
K8Z41_04395	COG0598	Magnesium transport protein CorA
K8Z41_04410	COG1846	Transcriptional regulator
K8Z41_04425	COG1131	(ABC) transporter
K8Z41_04430	COG1725	Transcriptional regulator
K8Z41_04435	COG1686	Belongs to the peptidase S11 family
K8Z41_04480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z41_04495	COG0697	spore germination
K8Z41_04500	COG0561	phosphatase activity
K8Z41_04505	COG4086	secreted protein
K8Z41_04510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K8Z41_04515	COG0456	acetyltransferase
K8Z41_04520	COG1547	Domain of unknown function (DUF309)
K8Z41_04545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K8Z41_04555	COG2188	Transcriptional regulator
K8Z41_04565	COG3711	transcriptional antiterminator
K8Z41_04570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z41_04570	COG2190	(PTS) system
K8Z41_04570	COG1263	PTS System
K8Z41_04595	COG0778	Nitroreductase
K8Z41_04600	COG2199	diguanylate cyclase activity
K8Z41_04610	COG2084	Dehydrogenase
K8Z41_04645	COG0436	Aminotransferase
K8Z41_04650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K8Z41_04680	COG0640	Transcriptional regulator
K8Z41_04685	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_04710	COG4974	Belongs to the 'phage' integrase family
K8Z41_04730	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_04735	COG1695	Transcriptional regulator
K8Z41_04765	COG0183	Belongs to the thiolase family
K8Z41_04800	COG3842	ATPase activity
K8Z41_04805	COG0366	Alpha amylase catalytic
K8Z41_04815	COG2182	Extracellular solute-binding protein
K8Z41_04820	COG1175	transmembrane transport
K8Z41_04825	COG3833	ABC-type maltose transport systems, permease component
K8Z41_04830	COG1609	Transcriptional regulator
K8Z41_04835	COG0436	Aminotransferase
K8Z41_04845	COG2205	protein histidine kinase activity
K8Z41_04855	COG3209	COG3209 Rhs family protein
K8Z41_04875	COG2814	Major facilitator Superfamily
K8Z41_04920	COG1408	metallophosphoesterase
K8Z41_04925	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_04930	COG2200	EAL domain
K8Z41_04945	COG4703	Protein of unknown function (DUF1797)
K8Z41_04955	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
K8Z41_04965	COG0517	IMP dehydrogenase activity
K8Z41_04970	COG0583	DNA-binding transcription factor activity
K8Z41_04990	COG0569	domain protein
K8Z41_04995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z41_05005	COG0561	phosphatase activity
K8Z41_05020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z41_05025	COG0022	dehydrogenase e1 component
K8Z41_05070	COG1982	Orn Lys Arg decarboxylase major
K8Z41_05090	COG0483	inositol monophosphate 1-phosphatase activity
K8Z41_05100	COG1217	gtp-binding protein TYPA
K8Z41_05115	COG4896	Protein conserved in bacteria
K8Z41_05125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K8Z41_05130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K8Z41_05140	COG0772	Belongs to the SEDS family
K8Z41_05145	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K8Z41_05180	COG3336	cytochrome c oxidase
K8Z41_05195	COG2340	Cysteine-rich secretory protein family
K8Z41_05210	COG0406	alpha-ribazole phosphatase activity
K8Z41_05215	COG3679	Belongs to the UPF0342 family
K8Z41_05230	COG0742	ribosomal rna small subunit methyltransferase
K8Z41_05240	COG3314	Sporulation integral membrane protein YlbJ
K8Z41_05245	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z41_05250	COG3480	Lon protease (S16) C-terminal proteolytic domain
K8Z41_05260	COG1399	metal-binding, possibly nucleic acid-binding protein
K8Z41_05265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K8Z41_05280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z41_05300	COG0768	penicillin binding
K8Z41_05305	COG0768	penicillin binding
K8Z41_05325	COG0772	Belongs to the SEDS family
K8Z41_05345	COG0849	cell division
K8Z41_05350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K8Z41_05360	COG1191	sigma factor activity
K8Z41_05365	COG1191	sigma factor activity
K8Z41_05370	COG1873	PFAM PRC-barrel domain
K8Z41_05380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K8Z41_05390	COG0762	integral membrane protein
K8Z41_05395	COG2302	S4 RNA-binding domain
K8Z41_05400	COG3599	regulation of cell shape
K8Z41_05420	COG0564	pseudouridine synthase activity
K8Z41_05480	COG3069	C4-dicarboxylate transmembrane transporter activity
K8Z41_05495	COG0006	proline dipeptidase activity
K8Z41_05505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z41_05510	COG1561	YicC-like family, N-terminal region
K8Z41_05530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z41_05535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K8Z41_05550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K8Z41_05550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K8Z41_05560	COG0631	protein serine/threonine phosphatase activity
K8Z41_05565	COG0515	serine threonine protein kinase
K8Z41_05565	COG2815	serine threonine protein kinase
K8Z41_05575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K8Z41_05580	COG1564	THIamine pyrophosphokinase
K8Z41_05595	COG1302	Protein conserved in bacteria
K8Z41_05600	COG1461	Dihydroxyacetone kinase
K8Z41_05605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K8Z41_05620	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K8Z41_05625	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_05630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z41_05645	COG3344	reverse transcriptase
K8Z41_05655	COG0552	protein localization to endoplasmic reticulum
K8Z41_05665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K8Z41_05675	COG1837	Belongs to the UPF0109 family
K8Z41_05715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K8Z41_05720	COG0758	DNA mediated transformation
K8Z41_05725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z41_05735	COG4974	Belongs to the 'phage' integrase family
K8Z41_05780	COG4589	Belongs to the CDS family
K8Z41_05790	COG0750	zinc metalloprotease
K8Z41_05810	COG0195	Participates in both transcription termination and antitermination
K8Z41_05815	COG2740	Nucleic-acid-binding protein implicated in transcription termination
K8Z41_05820	COG1358	cellular component organization or biogenesis
K8Z41_05830	COG1550	Protein conserved in bacteria
K8Z41_05835	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K8Z41_05845	COG0196	riboflavin kinase activity
K8Z41_05860	COG0726	polysaccharide deacetylase
K8Z41_05865	COG0612	Peptidase, M16
K8Z41_05870	COG1873	PFAM PRC-barrel domain
K8Z41_05875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K8Z41_05880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K8Z41_05885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z41_05890	COG0527	aspartate kinase activity
K8Z41_05900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z41_05905	COG0740	serine-type endopeptidase activity
K8Z41_05920	COG2188	Transcriptional regulator
K8Z41_05925	COG1744	ABC transporter substrate-binding protein PnrA-like
K8Z41_05930	COG3845	ABC transporter
K8Z41_05935	COG4603	Belongs to the binding-protein-dependent transport system permease family
K8Z41_05940	COG1079	Belongs to the binding-protein-dependent transport system permease family
K8Z41_05945	COG0612	Peptidase, M16
K8Z41_05950	COG0612	Peptidase, M16
K8Z41_05955	COG0300	oxidoreductase activity
K8Z41_05970	COG1426	Protein conserved in bacteria
K8Z41_05975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K8Z41_05995	COG1692	metallophosphoesterase
K8Z41_06000	COG2359	stage V sporulation protein S
K8Z41_06010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K8Z41_06010	COG0674	pyruvate-flavodoxin oxidoreductase activity
K8Z41_06015	COG1013	pyruvate-flavodoxin oxidoreductase activity
K8Z41_06025	COG4550	Control of competence regulator ComK, YlbF/YmcA
K8Z41_06050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z41_06055	COG1368	sulfuric ester hydrolase activity
K8Z41_06065	COG3773	Cell wall hydrolase
K8Z41_06070	COG1404	Belongs to the peptidase S8 family
K8Z41_06075	COG0823	Involved in the tonB-independent uptake of proteins
K8Z41_06080	COG2723	6-phospho-beta-galactosidase activity
K8Z41_06085	COG2188	Transcriptional regulator
K8Z41_06095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_06105	COG1346	cytolysis
K8Z41_06125	COG1086	Polysaccharide biosynthesis protein
K8Z41_06145	COG3300	MHYT domain
K8Z41_06145	COG5001	Diguanylate cyclase
K8Z41_06150	COG2267	carboxylic ester hydrolase activity
K8Z41_06170	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z41_06175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z41_06180	COG2169	Transcriptional regulator
K8Z41_06190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z41_06195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_06200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_06205	COG1120	ATPase activity
K8Z41_06210	COG2819	hydrolase of the alpha beta superfamily
K8Z41_06220	COG1937	Protein conserved in bacteria
K8Z41_06225	COG2608	mercury ion transmembrane transporter activity
K8Z41_06230	COG2217	Heavy metal translocating P-type atpase
K8Z41_06245	COG2116	formate transmembrane transporter activity
K8Z41_06250	COG1408	metallophosphoesterase
K8Z41_06260	COG1113	amino acid transport
K8Z41_06270	COG2322	membrane
K8Z41_06275	COG1979	alcohol dehydrogenase
K8Z41_06280	COG1349	DNA-binding transcription factor activity
K8Z41_06285	COG1105	Belongs to the carbohydrate kinase PfkB family
K8Z41_06290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z41_06290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z41_06290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K8Z41_06295	COG3584	3D domain protein
K8Z41_06295	COG1388	LysM domain
K8Z41_06325	COG0464	growth
K8Z41_06335	COG2860	membrane
K8Z41_06340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z41_06345	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
K8Z41_06350	COG0789	Transcriptional regulator
K8Z41_06355	COG0174	glutamine synthetase
K8Z41_06365	COG1695	Transcriptional regulator
K8Z41_06385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z41_06410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z41_06445	COG1132	(ABC) transporter
K8Z41_06450	COG1132	(ABC) transporter
K8Z41_06475	COG0730	response to heat
K8Z41_06490	COG1346	cytolysis
K8Z41_06500	COG0583	DNA-binding transcription factor activity
K8Z41_06530	COG1473	amidohydrolase
K8Z41_06540	COG0785	Cytochrome C biogenesis protein
K8Z41_06545	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z41_06570	COG2226	methyltransferase
K8Z41_06595	COG0010	Belongs to the arginase family
K8Z41_06600	COG1329	Transcriptional regulator
K8Z41_06610	COG3344	reverse transcriptase
K8Z41_06620	COG0069	glutamate synthase activity
K8Z41_06635	COG0346	lactoylglutathione lyase activity
K8Z41_06640	COG0400	carboxylic ester hydrolase activity
K8Z41_06645	COG5002	protein histidine kinase activity
K8Z41_06655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_06695	COG0830	nickel cation binding
K8Z41_06715	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
K8Z41_06745	COG1396	sequence-specific DNA binding
K8Z41_06750	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_06755	COG1268	BioY protein
K8Z41_06760	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_06765	COG0183	Belongs to the thiolase family
K8Z41_06780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z41_06790	COG2211	Major facilitator Superfamily
K8Z41_06820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K8Z41_06825	COG1132	(ABC) transporter
K8Z41_06840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z41_06875	COG0824	Thioesterase
K8Z41_06880	COG4841	protein insertion into membrane
K8Z41_06890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K8Z41_06890	COG1328	CTP reductase activity
K8Z41_06900	COG0745	RESPONSE REGULATOR receiver
K8Z41_06905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z41_06910	COG1832	CoA-binding protein
K8Z41_06915	COG0187	DNA topoisomerase II activity
K8Z41_06920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z41_06925	COG0673	inositol 2-dehydrogenase activity
K8Z41_06945	COG1131	(ABC) transporter
K8Z41_06955	COG1595	DNA-templated transcription, initiation
K8Z41_06965	COG1316	TRANSCRIPTIONal
K8Z41_06970	COG4166	transmembrane transport
K8Z41_06975	COG4166	transmembrane transport
K8Z41_06980	COG4166	transmembrane transport
K8Z41_06985	COG2226	methyltransferase
K8Z41_07020	COG0531	amino acid
K8Z41_07035	COG0697	spore germination
K8Z41_07040	COG3383	formate dehydrogenase (NAD+) activity
K8Z41_07045	COG2427	Protein of unknown function (DUF1641)
K8Z41_07050	COG5609	conserved protein (DUF2294)
K8Z41_07055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z41_07065	COG2116	formate transmembrane transporter activity
K8Z41_07070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z41_07075	COG0303	'Molybdopterin
K8Z41_07080	COG0314	molybdopterin synthase activity
K8Z41_07090	COG0489	protein tyrosine kinase activity
K8Z41_07105	COG3326	Membrane
K8Z41_07110	COG2962	Rard protein
K8Z41_07115	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
K8Z41_07120	COG1657	PFAM Prenyltransferase squalene oxidase
K8Z41_07130	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_07135	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_07145	COG4145	pantothenate transmembrane transporter activity
K8Z41_07160	COG0165	Argininosuccinate lyase
K8Z41_07170	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_07205	COG0716	FMN binding
K8Z41_07240	COG2720	vancomycin resistance protein
K8Z41_07245	COG2514	catechol 2,3-dioxygenase activity
K8Z41_07255	COG1285	pathogenesis
K8Z41_07265	COG3852	Histidine kinase
K8Z41_07290	COG0488	(ABC) transporter
K8Z41_07330	COG1404	Belongs to the peptidase S8 family
K8Z41_07365	COG0457	Tetratricopeptide repeat
K8Z41_07375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z41_07385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z41_07405	COG3344	reverse transcriptase
K8Z41_07435	COG0697	spore germination
K8Z41_07445	COG3397	chitin binding
K8Z41_07450	COG0823	Involved in the tonB-independent uptake of proteins
K8Z41_07460	COG1252	NADH dehydrogenase
K8Z41_07465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_07465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z41_07470	COG1183	phosphatidylcholine synthase activity
K8Z41_07495	COG0277	FAD linked oxidase domain protein
K8Z41_07500	COG0385	Bile acid
K8Z41_07510	COG0457	Tetratricopeptide repeat
K8Z41_07520	COG0604	alcohol dehydrogenase
K8Z41_07525	COG0640	Transcriptional regulator
K8Z41_07535	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z41_07560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z41_07590	COG1164	Oligoendopeptidase f
K8Z41_07595	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z41_07605	COG1193	negative regulation of DNA recombination
K8Z41_07620	COG2890	protein-(glutamine-N5) methyltransferase activity
K8Z41_07630	COG0583	DNA-binding transcription factor activity
K8Z41_07645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_07665	COG3739	integral membrane protein
K8Z41_07670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_07675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_07680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z41_07685	COG1247	-acetyltransferase
K8Z41_07695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z41_07700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
K8Z41_07730	COG2814	Major facilitator Superfamily
K8Z41_07735	COG1113	amino acid transport
K8Z41_07800	COG1151	hydroxylamine reductase activity
K8Z41_07855	COG1191	sigma factor activity
K8Z41_07880	COG1733	regulation of RNA biosynthetic process
K8Z41_07885	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z41_07890	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_07910	COG0384	phenazine biosynthesis protein PhzF
K8Z41_07930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_07950	COG0673	inositol 2-dehydrogenase activity
K8Z41_07955	COG2188	Transcriptional regulator
K8Z41_07985	COG0814	amino acid
K8Z41_08000	COG1733	regulation of RNA biosynthetic process
K8Z41_08005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z41_08005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K8Z41_08010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z41_08010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K8Z41_08020	COG0840	transmembrane signaling receptor activity
K8Z41_08050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K8Z41_08055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K8Z41_08060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z41_08065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K8Z41_08075	COG1070	Carbohydrate kinase
K8Z41_08080	COG2706	6-phosphogluconolactonase activity
K8Z41_08085	COG3813	Protein conserved in bacteria
K8Z41_08090	COG1357	PFAM Pentapeptide repeats (8 copies)
K8Z41_08100	COG0697	spore germination
K8Z41_08130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K8Z41_08140	COG0789	Transcriptional regulator
K8Z41_08145	COG1253	flavin adenine dinucleotide binding
K8Z41_08175	COG0477	Major facilitator Superfamily
K8Z41_08185	COG0500	methyltransferase
K8Z41_08210	COG0628	permease
K8Z41_08245	COG2365	Tyrosine phosphatase family
K8Z41_08255	COG1011	Hydrolase
K8Z41_08280	COG1131	(ABC) transporter
K8Z41_08290	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_08310	COG0469	pyruvate kinase activity
K8Z41_08320	COG0778	Nitroreductase
K8Z41_08325	COG1733	regulation of RNA biosynthetic process
K8Z41_08335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K8Z41_08355	COG1288	antiporter activity
K8Z41_08410	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z41_08420	COG2031	fatty acid transporter
K8Z41_08435	COG2814	Major facilitator Superfamily
K8Z41_08440	COG1846	Transcriptional regulator
K8Z41_08455	COG0477	Major facilitator Superfamily
K8Z41_08465	COG2843	Capsule synthesis protein
K8Z41_08470	COG1876	peptidase activity
K8Z41_08495	COG5444	nuclease activity
K8Z41_08605	COG1396	sequence-specific DNA binding
K8Z41_08625	COG1309	transcriptional regulator
K8Z41_08630	COG0367	asparagine synthase
K8Z41_08655	COG1760	l-serine dehydratase
K8Z41_08660	COG1760	l-serine dehydratase
K8Z41_08665	COG0814	amino acid
K8Z41_08675	COG3344	reverse transcriptase
K8Z41_08700	COG1533	DNA photolyase activity
K8Z41_08710	COG0076	glutamate decarboxylase activity
K8Z41_08720	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z41_08750	COG0772	Belongs to the SEDS family
K8Z41_08755	COG2239	Acts as a magnesium transporter
K8Z41_08765	COG0768	penicillin binding
K8Z41_08770	COG1595	DNA-templated transcription, initiation
K8Z41_08780	COG0768	penicillin binding
K8Z41_08785	COG0768	penicillin binding
K8Z41_08800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_08815	COG1131	(ABC) transporter
K8Z41_08825	COG1309	transcriptional regulator
K8Z41_08840	COG1960	acyl-CoA dehydrogenase activity
K8Z41_08845	COG0439	Biotin carboxylase
K8Z41_08850	COG0511	ligase activity, forming carbon-carbon bonds
K8Z41_08855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K8Z41_08860	COG1024	Enoyl-CoA hydratase
K8Z41_08865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K8Z41_08870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K8Z41_08890	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_08905	COG0572	uridine kinase
K8Z41_08925	COG1686	Belongs to the peptidase S11 family
K8Z41_08955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z41_08970	COG3227	Zinc metalloprotease (Elastase)
K8Z41_08975	COG2207	Transcriptional regulator
K8Z41_09035	COG1942	4-Oxalocrotonate Tautomerase
K8Z41_09040	COG0583	DNA-binding transcription factor activity
K8Z41_09050	COG1131	(ABC) transporter
K8Z41_09080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_09085	COG2368	4-hydroxyphenylacetate
K8Z41_09105	COG3344	reverse transcriptase
K8Z41_09125	COG2323	membrane
K8Z41_09130	COG0693	protein deglycase activity
K8Z41_09140	COG3386	PFAM SMP-30 Gluconolaconase
K8Z41_09150	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K8Z41_09155	COG3773	Cell wall hydrolase
K8Z41_09165	COG0745	RESPONSE REGULATOR receiver
K8Z41_09175	COG3344	reverse transcriptase
K8Z41_09185	COG0488	(ABC) transporter
K8Z41_09195	COG1136	(ABC) transporter
K8Z41_09200	COG0577	efflux transmembrane transporter activity
K8Z41_09220	COG0460	homoserine dehydrogenase
K8Z41_09225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_09235	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z41_09275	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_09300	COG2124	cytochrome p450
K8Z41_09335	COG0561	phosphatase activity
K8Z41_09340	COG5002	protein histidine kinase activity
K8Z41_09345	COG0768	penicillin binding
K8Z41_09355	COG1819	glycosyl
K8Z41_09360	COG1794	racemase activity, acting on amino acids and derivatives
K8Z41_09385	COG2205	protein histidine kinase activity
K8Z41_09390	COG0582	viral genome integration into host DNA
K8Z41_09435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z41_09450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z41_09460	COG0745	RESPONSE REGULATOR receiver
K8Z41_09465	COG5002	protein histidine kinase activity
K8Z41_09470	COG0604	alcohol dehydrogenase
K8Z41_09475	COG0671	phosphoesterase, PA-phosphatase related
K8Z41_09480	COG0768	penicillin binding
K8Z41_09525	COG2814	Major facilitator Superfamily
K8Z41_09530	COG2814	Major facilitator Superfamily
K8Z41_09550	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z41_09565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_09570	COG0697	spore germination
K8Z41_09605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z41_09615	COG2223	nitrite transmembrane transporter activity
K8Z41_09630	COG0592	DNA-directed DNA polymerase activity
K8Z41_09665	COG3878	Protein conserved in bacteria
K8Z41_09685	COG4667	esterase of the alpha-beta hydrolase superfamily
K8Z41_09725	COG0322	excinuclease ABC activity
K8Z41_09745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z41_09775	COG1011	Hydrolase
K8Z41_09780	COG0745	RESPONSE REGULATOR receiver
K8Z41_09785	COG5002	protein histidine kinase activity
K8Z41_09800	COG1136	(ABC) transporter
K8Z41_09805	COG0577	efflux transmembrane transporter activity
K8Z41_09810	COG1073	alpha beta
K8Z41_09815	COG0657	acetylesterase activity
K8Z41_09820	COG0076	glutamate decarboxylase activity
K8Z41_09835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z41_09865	COG1523	belongs to the glycosyl hydrolase 13 family
K8Z41_09870	COG3227	Zinc metalloprotease (Elastase)
K8Z41_09875	COG0737	Belongs to the 5'-nucleotidase family
K8Z41_09890	COG0201	protein transport
K8Z41_09895	COG0697	spore germination
K8Z41_09900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_09935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_09950	COG2959	enzyme of heme biosynthesis
K8Z41_09990	COG1309	transcriptional regulator
K8Z41_10020	COG3284	Transcriptional regulator
K8Z41_10050	COG1959	2 iron, 2 sulfur cluster binding
K8Z41_10065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z41_10070	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z41_10075	COG0022	dehydrogenase e1 component
K8Z41_10080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K8Z41_10090	COG2814	Major facilitator Superfamily
K8Z41_10105	COG3344	reverse transcriptase
K8Z41_10120	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_10125	COG0456	acetyltransferase
K8Z41_10125	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K8Z41_10165	COG4176	ABC-type proline glycine betaine transport system permease component
K8Z41_10170	COG4175	Glycine betaine
K8Z41_10170	COG0517	IMP dehydrogenase activity
K8Z41_10200	COG2153	protein acetylation
K8Z41_10205	COG3397	chitin binding
K8Z41_10210	COG1819	glycosyl
K8Z41_10230	COG2205	protein histidine kinase activity
K8Z41_10235	COG2226	methyltransferase
K8Z41_10240	COG2315	Protein conserved in bacteria
K8Z41_10285	COG0456	acetyltransferase
K8Z41_10290	COG3973	AAA domain
K8Z41_10300	COG2105	PFAM AIG2 family protein
K8Z41_10305	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z41_10345	COG4637	Psort location Cytoplasmic, score
K8Z41_10360	COG3397	chitin binding
K8Z41_10375	COG1162	GTPase activity
K8Z41_10380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K8Z41_10385	COG1115	amino acid carrier protein
K8Z41_10390	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_10395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K8Z41_10405	COG3938	Belongs to the proline racemase family
K8Z41_10410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z41_10450	COG0586	Pfam SNARE associated Golgi protein
K8Z41_10460	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z41_10470	COG4166	transmembrane transport
K8Z41_10480	COG4948	Mandelate Racemase Muconate Lactonizing
K8Z41_10495	COG0667	Aldo Keto reductase
K8Z41_10540	COG5002	protein histidine kinase activity
K8Z41_10540	COG3850	Histidine kinase
K8Z41_10545	COG0745	RESPONSE REGULATOR receiver
K8Z41_10565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K8Z41_10575	COG1164	Oligoendopeptidase f
K8Z41_10580	COG1307	EDD domain protein, DegV family
K8Z41_10620	COG2814	Major facilitator Superfamily
K8Z41_10630	COG1664	Polymer-forming cytoskeletal
K8Z41_10635	COG0789	Transcriptional regulator
K8Z41_10640	COG4533	DNA binding
K8Z41_10645	COG2814	Major facilitator Superfamily
K8Z41_10645	COG0477	Major facilitator Superfamily
K8Z41_10670	COG2261	transglycosylase associated protein
K8Z41_10685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K8Z41_10720	COG0436	Aminotransferase
K8Z41_10725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K8Z41_10735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K8Z41_10750	COG1131	(ABC) transporter
K8Z41_10800	COG0628	permease
K8Z41_10815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z41_10820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z41_10825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z41_10855	COG2746	aminoglycoside 3-N-acetyltransferase activity
K8Z41_10875	COG0697	spore germination
K8Z41_10900	COG4912	Dna alkylation repair
K8Z41_10905	COG0346	lactoylglutathione lyase activity
K8Z41_10910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_10920	COG0861	Integral membrane protein TerC family
K8Z41_10925	COG1368	sulfuric ester hydrolase activity
K8Z41_10930	COG0488	(ABC) transporter
K8Z41_10945	COG1033	growth of symbiont in host cell
K8Z41_10945	COG2409	Drug exporters of the RND superfamily
K8Z41_10950	COG1309	transcriptional regulator
K8Z41_10965	COG0287	Prephenate dehydrogenase
K8Z41_10980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K8Z41_10980	COG1605	Chorismate mutase
K8Z41_11020	COG3584	3D domain protein
K8Z41_11020	COG1388	LysM domain
K8Z41_11035	COG0277	FAD linked oxidase domain protein
K8Z41_11050	COG1879	ABC-type sugar transport system periplasmic component
K8Z41_11060	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z41_11070	COG2390	Transcriptional regulator
K8Z41_11075	COG1070	Carbohydrate kinase
K8Z41_11100	COG2329	Antibiotic biosynthesis monooxygenase
K8Z41_11120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z41_11140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K8Z41_11145	COG4187	Peptidase family M20/M25/M40
K8Z41_11150	COG1414	Transcriptional regulator
K8Z41_11155	COG0833	amino acid
K8Z41_11170	COG3239	Fatty acid desaturase
K8Z41_11180	COG2720	vancomycin resistance protein
K8Z41_11185	COG1785	Belongs to the alkaline phosphatase family
K8Z41_11195	COG3655	Transcriptional regulator
K8Z41_11215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_11220	COG0346	lactoylglutathione lyase activity
K8Z41_11250	COG0714	Associated with various cellular activities
K8Z41_11295	COG0463	Glycosyl transferase, family 2
K8Z41_11315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K8Z41_11320	COG0753	catalase activity
K8Z41_11360	COG0714	Associated with various cellular activities
K8Z41_11445	COG0778	Nitroreductase
K8Z41_11450	COG1846	Transcriptional regulator
K8Z41_11470	COG4884	unkown
K8Z41_11470	COG3831	ATPase activity
K8Z41_11495	COG0037	tRNA processing
K8Z41_11495	COG0590	tRNA wobble adenosine to inosine editing
K8Z41_11505	COG0456	acetyltransferase
K8Z41_11520	COG0697	spore germination
K8Z41_11525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_11565	COG0730	response to heat
K8Z41_11575	COG0833	amino acid
K8Z41_11620	COG0768	penicillin binding
K8Z41_11655	COG1984	allophanate hydrolase subunit 2
K8Z41_11660	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K8Z41_11665	COG1414	Transcriptional regulator
K8Z41_11675	COG3142	Participates in the control of copper homeostasis
K8Z41_11680	COG0640	Transcriptional regulator
K8Z41_11690	COG1960	acyl-CoA dehydrogenase activity
K8Z41_11705	COG3314	Sporulation integral membrane protein YlbJ
K8Z41_11715	COG0454	-acetyltransferase
K8Z41_11725	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K8Z41_11750	COG0574	Belongs to the PEP-utilizing enzyme family
K8Z41_11750	COG3848	Pyruvate phosphate dikinase
K8Z41_11770	COG1522	sequence-specific DNA binding
K8Z41_11775	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_11780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_11800	COG1063	alcohol dehydrogenase
K8Z41_11805	COG5002	protein histidine kinase activity
K8Z41_11830	COG2207	Transcriptional regulator
K8Z41_11850	COG0737	Belongs to the 5'-nucleotidase family
K8Z41_11855	COG2267	carboxylic ester hydrolase activity
K8Z41_11860	COG1335	isochorismatase
K8Z41_11880	COG0583	DNA-binding transcription factor activity
K8Z41_11890	COG2814	Major facilitator Superfamily
K8Z41_11925	COG0598	Magnesium transport protein CorA
K8Z41_11975	COG0415	Belongs to the DNA photolyase family
K8Z41_12000	COG0657	acetylesterase activity
K8Z41_12005	COG0288	reversible hydration of carbon dioxide
K8Z41_12015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z41_12020	COG5609	conserved protein (DUF2294)
K8Z41_12030	COG0456	acetyltransferase
K8Z41_12035	COG1575	Belongs to the MenA family. Type 1 subfamily
K8Z41_12045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_12055	COG0798	PFAM Bile acid sodium symporter
K8Z41_12060	COG0346	lactoylglutathione lyase activity
K8Z41_12065	COG0640	Transcriptional regulator
K8Z41_12070	COG2814	Major facilitator Superfamily
K8Z41_12075	COG1309	transcriptional regulator
K8Z41_12080	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_12085	COG1522	sequence-specific DNA binding
K8Z41_12100	COG0346	lactoylglutathione lyase activity
K8Z41_12185	COG2814	Major facilitator Superfamily
K8Z41_12200	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K8Z41_12210	COG1690	Belongs to the RtcB family
K8Z41_12220	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K8Z41_12240	COG0577	efflux transmembrane transporter activity
K8Z41_12245	COG3850	Histidine kinase
K8Z41_12245	COG5002	protein histidine kinase activity
K8Z41_12255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_12285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K8Z41_12315	COG3831	ATPase activity
K8Z41_12325	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_12325	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_12400	COG2239	Acts as a magnesium transporter
K8Z41_12405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_12415	COG0741	lytic transglycosylase activity
K8Z41_12485	COG2814	Major facilitator Superfamily
K8Z41_12500	COG1686	Belongs to the peptidase S11 family
K8Z41_12505	COG0110	maltose O-acetyltransferase activity
K8Z41_12510	COG0730	response to heat
K8Z41_12525	COG2002	toxin-antitoxin pair type II binding
K8Z41_12550	COG2195	Cleaves the N-terminal amino acid of tripeptides
K8Z41_12580	COG1846	Transcriptional regulator
K8Z41_12585	COG3961	Belongs to the TPP enzyme family
K8Z41_12590	COG2226	methyltransferase
K8Z41_12600	COG0500	methyltransferase
K8Z41_12600	COG3615	Tellurite resistance protein tehB
K8Z41_12620	COG1309	transcriptional regulator
K8Z41_12640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_12660	COG1846	Transcriptional regulator
K8Z41_12680	COG2971	BadF BadG BcrA BcrD
K8Z41_12705	COG1649	PFAM Uncharacterised BCR, COG1649
K8Z41_12730	COG1595	DNA-templated transcription, initiation
K8Z41_12735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K8Z41_12775	COG1396	sequence-specific DNA binding
K8Z41_12805	COG1132	(ABC) transporter
K8Z41_12810	COG1132	(ABC) transporter
K8Z41_12825	COG2258	MOSC domain
K8Z41_12830	COG0583	DNA-binding transcription factor activity
K8Z41_12850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K8Z41_12855	COG0583	DNA-binding transcription factor activity
K8Z41_12885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_12895	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z41_12920	COG1247	-acetyltransferase
K8Z41_12955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_12980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z41_13020	COG0028	Belongs to the TPP enzyme family
K8Z41_13035	COG1136	(ABC) transporter
K8Z41_13040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K8Z41_13045	COG1187	pseudouridine synthase activity
K8Z41_13050	COG2329	Antibiotic biosynthesis monooxygenase
K8Z41_13065	COG1115	amino acid carrier protein
K8Z41_13075	COG2318	DinB family
K8Z41_13085	COG0776	regulation of translation
K8Z41_13100	COG2814	Major facilitator Superfamily
K8Z41_13105	COG3251	PFAM MbtH domain protein
K8Z41_13110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z41_13115	COG3433	isochorismatase activity
K8Z41_13115	COG1535	isochorismatase
K8Z41_13120	COG1021	2,3-dihydroxybenzoate-AMP ligase
K8Z41_13125	COG1169	isochorismate synthase
K8Z41_13130	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_13135	COG2223	nitrite transmembrane transporter activity
K8Z41_13155	COG0419	ATPase involved in DNA repair
K8Z41_13160	COG0420	3'-5' exonuclease activity
K8Z41_13175	COG1024	Enoyl-CoA hydratase
K8Z41_13180	COG1280	lysine exporter protein (LysE YggA)
K8Z41_13190	COG2084	Dehydrogenase
K8Z41_13195	COG1960	acyl-CoA dehydrogenase activity
K8Z41_13200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K8Z41_13205	COG2079	MmgE PrpD family protein
K8Z41_13210	COG0372	Belongs to the citrate synthase family
K8Z41_13215	COG4841	protein insertion into membrane
K8Z41_13220	COG2814	Major facilitator Superfamily
K8Z41_13230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z41_13230	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z41_13250	COG0300	oxidoreductase activity
K8Z41_13335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z41_13340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K8Z41_13345	COG0671	phosphoesterase, PA-phosphatase related
K8Z41_13355	COG3064	Membrane
K8Z41_13355	COG4991	sh3 domain protein
K8Z41_13355	COG0515	serine threonine protein kinase
K8Z41_13390	COG1509	lysine 2,3-aminomutase activity
K8Z41_13395	COG3829	transcription factor binding
K8Z41_13400	COG0456	acetyltransferase
K8Z41_13405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z41_13410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K8Z41_13415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K8Z41_13420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z41_13435	COG5506	Protein of unknown function (DUF1694)
K8Z41_13440	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_13445	COG1253	flavin adenine dinucleotide binding
K8Z41_13480	COG1174	glycine betaine transport
K8Z41_13485	COG0517	IMP dehydrogenase activity
K8Z41_13485	COG1125	glycine betaine transport
K8Z41_13520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K8Z41_13545	COG1064	alcohol dehydrogenase
K8Z41_13550	COG0384	phenazine biosynthesis protein PhzF
K8Z41_13555	COG1737	Transcriptional regulator
K8Z41_13560	COG2197	response regulator
K8Z41_13565	COG2203	Gaf domain
K8Z41_13565	COG4585	Histidine kinase
K8Z41_13570	COG0668	transmembrane transport
K8Z41_13585	COG1335	isochorismatase
K8Z41_13605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z41_13610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z41_13630	COG0367	asparagine synthase
K8Z41_13635	COG0071	Belongs to the small heat shock protein (HSP20) family
K8Z41_13640	COG1999	signal sequence binding
K8Z41_13650	COG1307	EDD domain protein, DegV family
K8Z41_13660	COG0805	protein transport
K8Z41_13670	COG1272	protein, Hemolysin III
K8Z41_13675	COG0204	Acyl-transferase
K8Z41_13685	COG0768	penicillin binding
K8Z41_13700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z41_13715	COG0546	phosphoglycolate phosphatase activity
K8Z41_13725	COG4473	ABC transporter
K8Z41_13730	COG1131	(ABC) transporter
K8Z41_13740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K8Z41_13745	COG3655	Transcriptional regulator
K8Z41_13755	COG0456	acetyltransferase
K8Z41_13765	COG1794	racemase activity, acting on amino acids and derivatives
K8Z41_13775	COG2610	gluconate transmembrane transporter activity
K8Z41_13800	COG0733	neurotransmitter:sodium symporter activity
K8Z41_13805	COG0017	Asparaginyl-tRNA synthetase
K8Z41_13860	COG0018	arginyl-trna synthetase
K8Z41_13865	COG2521	methyltransferase
K8Z41_13865	COG2136	Putative SAM-dependent methyltransferase
K8Z41_13880	COG1413	lyase activity
K8Z41_13890	COG0629	single-stranded DNA binding
K8Z41_14000	COG0488	(ABC) transporter
K8Z41_14005	COG1418	mRNA catabolic process
K8Z41_14020	COG0457	Tetratricopeptide repeat
K8Z41_14070	COG2359	stage V sporulation protein S
K8Z41_14105	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
K8Z41_14110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z41_14115	COG2146	nitrite reductase [NAD(P)H] activity
K8Z41_14120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K8Z41_14120	COG1587	Uroporphyrinogen-III synthase
K8Z41_14130	COG1648	precorrin-2 dehydrogenase activity
K8Z41_14140	COG2223	nitrite transmembrane transporter activity
K8Z41_14145	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K8Z41_14150	COG0314	molybdopterin synthase activity
K8Z41_14155	COG0303	'Molybdopterin
K8Z41_14160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z41_14165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z41_14170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z41_14175	COG2181	nitrate reductase activity
K8Z41_14180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
K8Z41_14185	COG1140	nitrate reductase beta subunit
K8Z41_14190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
K8Z41_14200	COG0714	Associated with various cellular activities
K8Z41_14205	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
K8Z41_14210	COG1305	Transglutaminase-like
K8Z41_14215	COG0386	Belongs to the glutathione peroxidase family
K8Z41_14230	COG0426	domain, Protein
K8Z41_14230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z41_14245	COG1595	DNA-templated transcription, initiation
K8Z41_14255	COG0604	alcohol dehydrogenase
K8Z41_14265	COG0346	lactoylglutathione lyase activity
K8Z41_14270	COG1082	Xylose isomerase domain protein TIM barrel
K8Z41_14290	COG2226	methyltransferase
K8Z41_14315	COG3874	Sporulation protein YtfJ
K8Z41_14415	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z41_14450	COG0456	acetyltransferase
K8Z41_14480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_14485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_14490	COG1819	glycosyl
K8Z41_14505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z41_14520	COG0561	phosphatase activity
K8Z41_14570	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_14600	COG3344	reverse transcriptase
K8Z41_14645	COG0740	serine-type endopeptidase activity
K8Z41_14655	COG1802	Transcriptional regulator
K8Z41_14655	COG4626	Terminase
K8Z41_14700	COG0582	viral genome integration into host DNA
K8Z41_14775	COG3646	Phage regulatory protein
K8Z41_14825	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z41_14840	COG2211	Major facilitator Superfamily
K8Z41_14855	COG1876	peptidase activity
K8Z41_14865	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z41_14885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K8Z41_14890	COG1114	Component of the transport system for branched-chain amino acids
K8Z41_14910	COG1253	flavin adenine dinucleotide binding
K8Z41_14915	COG2839	Protein conserved in bacteria
K8Z41_14920	COG0702	epimerase
K8Z41_14935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z41_14945	COG1607	acyl-coa hydrolase
K8Z41_14950	COG3689	TIGRFAM TIGR03943 family protein
K8Z41_14955	COG0701	Predicted permease
K8Z41_14965	COG2244	polysaccharide biosynthetic process
K8Z41_14970	COG0586	Pfam SNARE associated Golgi protein
K8Z41_14975	COG1051	belongs to the nudix hydrolase family
K8Z41_14980	COG5337	Spore coat protein CotH
K8Z41_15005	COG4166	transmembrane transport
K8Z41_15015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K8Z41_15025	COG0702	epimerase
K8Z41_15035	COG3344	reverse transcriptase
K8Z41_15050	COG0803	Belongs to the bacterial solute-binding protein 9 family
K8Z41_15055	COG0456	acetyltransferase
K8Z41_15060	COG0523	cobalamin synthesis protein
K8Z41_15070	COG4989	oxidoreductase activity
K8Z41_15075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_15080	COG1231	oxidoreductase activity
K8Z41_15090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z41_15110	COG0783	Belongs to the Dps family
K8Z41_15115	COG3949	Membrane
K8Z41_15130	COG0840	transmembrane signaling receptor activity
K8Z41_15155	COG3152	Membrane
K8Z41_15160	COG2814	Major facilitator Superfamily
K8Z41_15165	COG0667	Aldo Keto reductase
K8Z41_15170	COG0640	Transcriptional regulator
K8Z41_15175	COG1404	Belongs to the peptidase S8 family
K8Z41_15180	COG2002	toxin-antitoxin pair type II binding
K8Z41_15185	COG0577	efflux transmembrane transporter activity
K8Z41_15220	COG1752	Esterase of the alpha-beta hydrolase superfamily
K8Z41_15230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_15235	COG1279	arginine transmembrane transporter activity
K8Z41_15240	COG2814	Major facilitator Superfamily
K8Z41_15250	COG1082	Xylose isomerase domain protein TIM barrel
K8Z41_15260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z41_15305	COG1247	-acetyltransferase
K8Z41_15310	COG1285	pathogenesis
K8Z41_15325	COG5002	protein histidine kinase activity
K8Z41_15330	COG0745	RESPONSE REGULATOR receiver
K8Z41_15340	COG1316	TRANSCRIPTIONal
K8Z41_15365	COG0460	homoserine dehydrogenase
K8Z41_15370	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_15400	COG0300	oxidoreductase activity
K8Z41_15405	COG5002	protein histidine kinase activity
K8Z41_15410	COG0745	RESPONSE REGULATOR receiver
K8Z41_15415	COG1132	(ABC) transporter
K8Z41_15425	COG1388	LysM domain
K8Z41_15425	COG0791	NLP P60 protein
K8Z41_15440	COG1686	Belongs to the peptidase S11 family
K8Z41_15480	COG1216	Glycosyl transferase, family 2
K8Z41_15490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K8Z41_15495	COG4988	ABC transporter
K8Z41_15500	COG1294	oxidase, subunit
K8Z41_15505	COG1271	oxidase subunit
K8Z41_15520	COG1942	4-Oxalocrotonate Tautomerase
K8Z41_15530	COG0583	DNA-binding transcription factor activity
K8Z41_15550	COG0411	ABC transporter
K8Z41_15560	COG0523	cobalamin synthesis protein
K8Z41_15565	COG1231	oxidoreductase activity
K8Z41_15575	COG0628	permease
K8Z41_15585	COG0778	Nitroreductase
K8Z41_15590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z41_15595	COG1959	2 iron, 2 sulfur cluster binding
K8Z41_15600	COG0583	DNA-binding transcription factor activity
K8Z41_15605	COG0697	spore germination
K8Z41_15610	COG4549	nuclear export factor GLE1
K8Z41_15615	COG1276	copper resistance
K8Z41_15615	COG2372	response to copper ion
K8Z41_15625	COG1114	Component of the transport system for branched-chain amino acids
K8Z41_15645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K8Z41_15655	COG2132	Multicopper oxidase
K8Z41_15665	COG0006	proline dipeptidase activity
K8Z41_15675	COG4846	Membrane protein involved in cytochrome C biogenesis
K8Z41_15690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K8Z41_15695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z41_15705	COG2390	Transcriptional regulator
K8Z41_15710	COG1309	transcriptional regulator
K8Z41_15745	COG0531	amino acid
K8Z41_15750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K8Z41_15765	COG1914	H( )-stimulated, divalent metal cation uptake system
K8Z41_15770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_15775	COG4166	transmembrane transport
K8Z41_15795	COG0427	acetyl-CoA hydrolase
K8Z41_15800	COG3279	Response regulator of the LytR AlgR family
K8Z41_15810	COG3384	dioxygenase
K8Z41_15815	COG2814	Major facilitator Superfamily
K8Z41_15840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K8Z41_15860	COG0028	Belongs to the TPP enzyme family
K8Z41_15865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z41_15875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z41_15895	COG2323	membrane
K8Z41_15900	COG5566	PFAM Mor transcription activator
K8Z41_15905	COG0733	neurotransmitter:sodium symporter activity
K8Z41_15925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z41_15930	COG2223	nitrite transmembrane transporter activity
K8Z41_15935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K8Z41_15945	COG0477	Major facilitator Superfamily
K8Z41_15955	COG1695	Transcriptional regulator
K8Z41_15970	COG2814	Major facilitator Superfamily
K8Z41_16005	COG3620	sequence-specific DNA binding
K8Z41_16025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z41_16030	COG0784	Response regulator, receiver
K8Z41_16035	COG4191	Histidine kinase
K8Z41_16040	COG0281	malic enzyme
K8Z41_16045	COG1027	Aspartate ammonia-lyase
K8Z41_16060	COG0528	UMP kinase activity
K8Z41_16065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z41_16085	COG1131	(ABC) transporter
K8Z41_16120	COG2733	membrane
K8Z41_16140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z41_16165	COG3340	Belongs to the peptidase S51 family
K8Z41_16170	COG0534	Mate efflux family protein
K8Z41_16200	COG0789	Transcriptional regulator
K8Z41_16205	COG1757	Na H antiporter
K8Z41_16220	COG0701	Predicted permease
K8Z41_16225	COG0523	cobalamin synthesis protein
K8Z41_16235	COG0697	spore germination
K8Z41_16240	COG1802	Transcriptional regulator
K8Z41_16270	COG0367	asparagine synthase
K8Z41_16295	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_16310	COG0406	alpha-ribazole phosphatase activity
K8Z41_16350	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z41_16355	COG3842	ATPase activity
K8Z41_16360	COG0583	DNA-binding transcription factor activity
K8Z41_16420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K8Z41_16425	COG4786	Flagellar basal body rod
K8Z41_16430	COG1419	protein localization to endoplasmic reticulum
K8Z41_16435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z41_16440	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K8Z41_16450	COG1987	bacterial-type flagellum assembly
K8Z41_16455	COG1338	Plays a role in the flagellum-specific transport system
K8Z41_16465	COG1776	CheC inhibitor of MCP methylation
K8Z41_16465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z41_16470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z41_16480	COG0741	lytic transglycosylase activity
K8Z41_16485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z41_16490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z41_16495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z41_16500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z41_16510	COG0835	chemotaxis
K8Z41_16510	COG0784	Response regulator, receiver
K8Z41_16545	COG1157	protein secretion by the type III secretion system
K8Z41_16555	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z41_16560	COG1766	The M ring may be actively involved in energy transduction
K8Z41_16570	COG1558	bacterial-type flagellum-dependent cell motility
K8Z41_16575	COG1815	bacterial-type flagellum-dependent cell motility
K8Z41_16595	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K8Z41_16600	COG1256	bacterial-type flagellum assembly
K8Z41_16620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z41_16635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K8Z41_16635	COG1776	CheC inhibitor of MCP methylation
K8Z41_16640	COG2198	Histidine kinase
K8Z41_16640	COG0643	Histidine kinase
K8Z41_16645	COG2201	protein-glutamate methylesterase activity
K8Z41_16650	COG1360	Flagellar Motor Protein
K8Z41_16655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K8Z41_16665	COG1923	regulation of RNA biosynthetic process
K8Z41_16705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K8Z41_16710	COG2323	membrane
K8Z41_16720	COG4978	Transcriptional regulator
K8Z41_16720	COG0789	Transcriptional regulator
K8Z41_16725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z41_16730	COG0475	glutathione-regulated potassium exporter activity
K8Z41_16740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K8Z41_16745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z41_16765	COG1280	lysine exporter protein (LysE YggA)
K8Z41_16770	COG3403	YqcI/YcgG family
K8Z41_16805	COG0328	RNA-DNA hybrid ribonuclease activity
K8Z41_16825	COG0454	-acetyltransferase
K8Z41_16840	COG0438	transferase activity, transferring glycosyl groups
K8Z41_16845	COG1215	transferase activity, transferring glycosyl groups
K8Z41_16860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K8Z41_16870	COG3944	biosynthesis protein
K8Z41_16885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K8Z41_16935	COG0456	acetyltransferase
K8Z41_16945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z41_16950	COG2311	Membrane
K8Z41_16955	COG2233	PERMEase
K8Z41_16965	COG0024	Methionine aminopeptidase
K8Z41_16975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K8Z41_16980	COG1199	ATP-dependent helicase activity
K8Z41_16990	COG0116	Belongs to the methyltransferase superfamily
K8Z41_17045	COG4499	WXG100 protein secretion system (Wss), protein YukC
K8Z41_17045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z41_17055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K8Z41_17060	COG3935	DnaD domain protein
K8Z41_17080	COG1199	ATP-dependent helicase activity
K8Z41_17080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K8Z41_17115	COG0438	transferase activity, transferring glycosyl groups
K8Z41_17135	COG1694	Mazg nucleotide pyrophosphohydrolase
K8Z41_17140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_17155	COG2738	Putative neutral zinc metallopeptidase
K8Z41_17170	COG4347	Protein of unknown function (DUF1405)
K8Z41_17175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z41_17175	COG2010	Cytochrome c
K8Z41_17180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K8Z41_17200	COG0457	Tetratricopeptide repeat
K8Z41_17230	COG0142	geranyltranstransferase activity
K8Z41_17240	COG0142	geranyltranstransferase activity
K8Z41_17255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
K8Z41_17325	COG0252	asparaginase activity
K8Z41_17330	COG0492	ferredoxin-NADP+ reductase activity
K8Z41_17350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K8Z41_17360	COG0789	Transcriptional regulator
K8Z41_17365	COG1408	metallophosphoesterase
K8Z41_17375	COG1266	CAAX protease self-immunity
K8Z41_17380	COG0514	ATP-dependent DNA helicase (RecQ)
K8Z41_17390	COG1141	Ferredoxin
K8Z41_17395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
K8Z41_17410	COG2096	Adenosyltransferase
K8Z41_17415	COG5002	protein histidine kinase activity
K8Z41_17420	COG0745	RESPONSE REGULATOR receiver
K8Z41_17425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K8Z41_17430	COG1333	cytochrome c biogenesis protein
K8Z41_17440	COG1187	pseudouridine synthase activity
K8Z41_17445	COG0700	Nucleoside recognition
K8Z41_17450	COG2715	membrane protein required for spore maturation
K8Z41_17455	COG1686	Belongs to the peptidase S11 family
K8Z41_17460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K8Z41_17475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K8Z41_17475	COG0392	lysyltransferase activity
K8Z41_17490	COG5002	protein histidine kinase activity
K8Z41_17495	COG0582	viral genome integration into host DNA
K8Z41_17505	COG1801	Protein of unknown function DUF72
K8Z41_17510	COG3852	Histidine kinase
K8Z41_17525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z41_17530	COG1392	Phosphate transport regulator
K8Z41_17535	COG0306	phosphate transporter
K8Z41_17540	COG0730	response to heat
K8Z41_17590	COG1114	Component of the transport system for branched-chain amino acids
K8Z41_17600	COG2197	response regulator
K8Z41_17605	COG4585	Histidine kinase
K8Z41_17610	COG4758	membrane
K8Z41_17625	COG1757	Na H antiporter
K8Z41_17650	COG0733	neurotransmitter:sodium symporter activity
K8Z41_17655	COG1648	precorrin-2 dehydrogenase activity
K8Z41_17675	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K8Z41_17680	COG0529	Catalyzes the synthesis of activated sulfate
K8Z41_17700	COG0019	diaminopimelate decarboxylase activity
K8Z41_17710	COG1368	sulfuric ester hydrolase activity
K8Z41_17715	COG1183	phosphatidylcholine synthase activity
K8Z41_17730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K8Z41_17805	COG0440	acetolactate synthase activity
K8Z41_17810	COG0028	Belongs to the TPP enzyme family
K8Z41_17815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z41_17835	COG3874	Sporulation protein YtfJ
K8Z41_17840	COG4709	membrane
K8Z41_17845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z41_17850	COG1301	dicarboxylic acid transport
K8Z41_17860	COG1846	Transcriptional regulator
K8Z41_17910	COG0716	FMN binding
K8Z41_17935	COG1696	Membrane protein involved in D-alanine export
K8Z41_17945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
K8Z41_17950	COG2070	2-Nitropropane dioxygenase
K8Z41_17955	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z41_17965	COG1335	isochorismatase
K8Z41_17975	COG1522	sequence-specific DNA binding
K8Z41_17995	COG1131	(ABC) transporter
K8Z41_18005	COG1131	(ABC) transporter
K8Z41_18010	COG1725	Transcriptional regulator
K8Z41_18015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z41_18025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K8Z41_18030	COG1780	Probably involved in ribonucleotide reductase function
K8Z41_18060	COG4873	Protein conserved in bacteria
K8Z41_18075	COG0720	synthase
K8Z41_18085	COG5002	protein histidine kinase activity
K8Z41_18095	COG2318	DinB family
K8Z41_18105	COG1846	Transcriptional regulator
K8Z41_18110	COG3852	Histidine kinase
K8Z41_18120	COG2861	carbohydrate metabolic process
K8Z41_18130	COG0235	Class ii aldolase
K8Z41_18140	COG1349	DNA-binding transcription factor activity
K8Z41_18165	COG3842	ATPase activity
K8Z41_18170	COG1840	ABC-type Fe3 transport system, periplasmic component
K8Z41_18185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z41_18195	COG3243	poly(R)-hydroxyalkanoic acid synthase
K8Z41_18200	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_18220	COG2030	dehydratase
K8Z41_18230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K8Z41_18235	COG0861	Integral membrane protein TerC family
K8Z41_18240	COG2116	formate transmembrane transporter activity
K8Z41_18250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
K8Z41_18270	COG2186	Transcriptional regulator
K8Z41_18275	COG5002	protein histidine kinase activity
K8Z41_18280	COG0745	RESPONSE REGULATOR receiver
K8Z41_18290	COG3835	regulator
K8Z41_18295	COG0277	FAD linked oxidase domain protein
K8Z41_18300	COG0247	lactate metabolic process
K8Z41_18305	COG2340	Cysteine-rich secretory protein family
K8Z41_18315	COG0564	pseudouridine synthase activity
K8Z41_18325	COG2409	Drug exporters of the RND superfamily
K8Z41_18340	COG1177	transmembrane transport
K8Z41_18345	COG1176	ABC-type spermidine putrescine transport system, permease component I
K8Z41_18355	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_18390	COG0681	Belongs to the peptidase S26 family
K8Z41_18395	COG1686	Belongs to the peptidase S11 family
K8Z41_18405	COG2226	methyltransferase
K8Z41_18425	COG1668	transmembrane transport
K8Z41_18430	COG4152	abc transporter atp-binding protein
K8Z41_18470	COG1476	TRANSCRIPTIONal
K8Z41_18480	COG0508	dehydrogenase complex catalyzes the overall conversion of
K8Z41_18500	COG2226	methyltransferase
K8Z41_18545	COG5634	Uncharacterized conserved protein (DUF2278)
K8Z41_18550	COG1620	l-lactate permease
K8Z41_18585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K8Z41_18585	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z41_18595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z41_18620	COG2382	esterase
K8Z41_18630	COG2153	protein acetylation
K8Z41_18675	COG1091	dTDP-4-dehydrorhamnose reductase activity
K8Z41_18690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K8Z41_18710	COG0463	Glycosyl transferase, family 2
K8Z41_18710	COG0457	Tetratricopeptide repeat
K8Z41_18730	COG1216	Glycosyl transferase, family 2
K8Z41_18735	COG0772	Belongs to the SEDS family
K8Z41_18750	COG0564	pseudouridine synthase activity
K8Z41_18760	COG2357	RelA SpoT domain protein
K8Z41_18770	COG4116	CYTH
K8Z41_18775	COG2346	COG2346, Truncated hemoglobins
K8Z41_18790	COG1164	Oligoendopeptidase f
K8Z41_18800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z41_18810	COG0861	Integral membrane protein TerC family
K8Z41_18825	COG4166	transmembrane transport
K8Z41_18830	COG0534	Mate efflux family protein
K8Z41_18835	COG4608	Belongs to the ABC transporter superfamily
K8Z41_18840	COG0444	Belongs to the ABC transporter superfamily
K8Z41_18845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z41_18850	COG0601	transmembrane transport
K8Z41_18855	COG4166	transmembrane transport
K8Z41_18865	COG0180	Tryptophanyl-tRNA synthetase
K8Z41_18875	COG5504	Zn-dependent protease
K8Z41_18880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z41_18885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z41_18900	COG2267	carboxylic ester hydrolase activity
K8Z41_18920	COG0561	phosphatase activity
K8Z41_18935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_18960	COG2996	Protein conserved in bacteria
K8Z41_18980	COG0004	ammonium transporteR
K8Z41_18985	COG3339	Conserved Protein
K8Z41_19010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K8Z41_19020	COG0753	catalase activity
K8Z41_19050	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_19050	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_19050	COG1388	LysM domain
K8Z41_19055	COG4824	toxin secretion phage lysis holin
K8Z41_19125	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_19160	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_19185	COG3331	DNA recombination
K8Z41_19285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K8Z41_19300	COG0367	asparagine synthase
K8Z41_19325	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z41_19385	COG0398	Pfam SNARE associated Golgi protein
K8Z41_19405	COG1278	Cold shock
K8Z41_19420	COG2224	Isocitrate lyase
K8Z41_19425	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K8Z41_19435	COG3693	PFAM glycoside hydrolase, family 10
K8Z41_19440	COG0840	transmembrane signaling receptor activity
K8Z41_19445	COG0501	Belongs to the peptidase M48B family
K8Z41_19465	COG0745	RESPONSE REGULATOR receiver
K8Z41_19480	COG3708	Transcriptional regulator
K8Z41_19480	COG2207	Transcriptional regulator
K8Z41_19485	COG1595	DNA-templated transcription, initiation
K8Z41_19495	COG1078	dGTPase activity
K8Z41_19500	COG1408	metallophosphoesterase
K8Z41_19505	COG1073	alpha beta
K8Z41_19595	COG4208	sulfate ABC transporter
K8Z41_19605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K8Z41_19615	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_19625	COG0095	Lipoate-protein ligase
K8Z41_19630	COG1234	tRNA 3'-trailer cleavage
K8Z41_19640	COG1609	Transcriptional regulator
K8Z41_19645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_19675	COG1511	domain protein
K8Z41_19675	COG1511	domain protein
K8Z41_19680	COG1309	transcriptional regulator
K8Z41_19715	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K8Z41_19730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z41_19735	COG2329	Antibiotic biosynthesis monooxygenase
K8Z41_19740	COG3428	Bacterial PH domain
K8Z41_19745	COG3402	PFAM membrane-flanked domain
K8Z41_19750	COG0697	spore germination
K8Z41_19785	COG3428	Bacterial PH domain
K8Z41_19790	COG3402	PFAM membrane-flanked domain
K8Z41_19800	COG1309	transcriptional regulator
K8Z41_19815	COG4473	ABC transporter
K8Z41_19820	COG1131	(ABC) transporter
K8Z41_19825	COG0537	adenosine 5'-monophosphoramidase activity
K8Z41_19830	COG4980	gas vesicle protein
K8Z41_19855	COG3973	AAA domain
K8Z41_19860	COG0772	Belongs to the SEDS family
K8Z41_19870	COG1595	DNA-templated transcription, initiation
K8Z41_19885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K8Z41_19895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K8Z41_19900	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z41_19905	COG3620	sequence-specific DNA binding
K8Z41_19910	COG2140	Oxalate decarboxylase
K8Z41_19940	COG0457	Tetratricopeptide repeat
K8Z41_19945	COG0346	lactoylglutathione lyase activity
K8Z41_19950	COG0346	lactoylglutathione lyase activity
K8Z41_19975	COG4717	serine-type aminopeptidase activity
K8Z41_19980	COG0420	3'-5' exonuclease activity
K8Z41_20000	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K8Z41_20010	COG2186	Transcriptional regulator
K8Z41_20055	COG2205	protein histidine kinase activity
K8Z41_20055	COG5002	protein histidine kinase activity
K8Z41_20055	COG0784	Response regulator, receiver
K8Z41_20060	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K8Z41_20065	COG2208	phosphoserine phosphatase activity
K8Z41_20075	COG1191	sigma factor activity
K8Z41_20150	COG2373	Large extracellular alpha-helical protein
K8Z41_20190	COG2376	Dihydroxyacetone kinase
K8Z41_20200	COG2376	Dihydroxyacetone kinase
K8Z41_20225	COG0640	Transcriptional regulator
K8Z41_20230	COG2814	Major facilitator Superfamily
K8Z41_20250	COG1183	phosphatidylcholine synthase activity
K8Z41_20300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K8Z41_20315	COG1522	sequence-specific DNA binding
K8Z41_20320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z41_20355	COG1073	alpha beta
K8Z41_20375	COG3344	reverse transcriptase
K8Z41_20395	COG2020	methyltransferase activity
K8Z41_20445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_20465	COG0477	Major facilitator Superfamily
K8Z41_20475	COG1842	Phage shock protein A
K8Z41_20485	COG1288	antiporter activity
K8Z41_20490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K8Z41_20515	COG0305	Participates in initiation and elongation during chromosome replication
K8Z41_20530	COG0305	Participates in initiation and elongation during chromosome replication
K8Z41_20545	COG0494	nUDIX hydrolase
K8Z41_20550	COG3181	Tripartite tricarboxylate transporter family receptor
K8Z41_20555	COG4565	transcriptional regulatory protein
K8Z41_20560	COG3290	protein histidine kinase activity
K8Z41_20565	COG0477	Major facilitator Superfamily
K8Z41_20665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_20680	COG0322	excinuclease ABC activity
K8Z41_20685	COG4608	Belongs to the ABC transporter superfamily
K8Z41_20690	COG0444	Belongs to the ABC transporter superfamily
K8Z41_20695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z41_20700	COG0601	transmembrane transport
K8Z41_20740	COG1363	Peptidase, m42
K8Z41_20760	COG1024	Enoyl-CoA hydratase
K8Z41_20780	COG2244	polysaccharide biosynthetic process
K8Z41_20785	COG0659	secondary active sulfate transmembrane transporter activity
K8Z41_20800	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_20805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K8Z41_20810	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_20810	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_20820	COG0561	phosphatase activity
K8Z41_20835	COG3527	Alpha-acetolactate decarboxylase
K8Z41_20840	COG0028	Belongs to the TPP enzyme family
K8Z41_20870	COG0189	ligase activity
K8Z41_20885	COG1126	abc transporter atp-binding protein
K8Z41_20890	COG0765	amino acid transport
K8Z41_20895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z41_20900	COG1132	(ABC) transporter
K8Z41_20905	COG1132	(ABC) transporter
K8Z41_20910	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_20925	COG0531	amino acid
K8Z41_20935	COG0753	catalase activity
K8Z41_20940	COG0693	protein deglycase activity
K8Z41_20955	COG2211	Major facilitator Superfamily
K8Z41_20960	COG4533	DNA binding
K8Z41_20975	COG1733	regulation of RNA biosynthetic process
K8Z41_20980	COG2814	Major facilitator Superfamily
K8Z41_20985	COG1309	transcriptional regulator
K8Z41_21005	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_21010	COG0165	Argininosuccinate lyase
K8Z41_21010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K8Z41_21015	COG1522	sequence-specific DNA binding
K8Z41_21035	COG2259	Doxx family
K8Z41_21045	COG1263	PTS System
K8Z41_21045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z41_21055	COG1737	Transcriptional regulator
K8Z41_21065	COG0475	glutathione-regulated potassium exporter activity
K8Z41_21070	COG0531	amino acid
K8Z41_21105	COG0586	Pfam SNARE associated Golgi protein
K8Z41_21140	COG3546	catalase activity
K8Z41_21145	COG1114	Component of the transport system for branched-chain amino acids
K8Z41_21160	COG5522	Integral membrane protein (intg_mem_TP0381)
K8Z41_21170	COG1136	(ABC) transporter
K8Z41_21175	COG0577	efflux transmembrane transporter activity
K8Z41_21180	COG1388	LysM domain
K8Z41_21180	COG3584	3D domain protein
K8Z41_21205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z41_21210	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z41_21215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z41_21215	COG3711	transcriptional antiterminator
K8Z41_21230	COG1283	sodium-dependent phosphate transmembrane transporter activity
K8Z41_21235	COG0604	alcohol dehydrogenase
K8Z41_21240	COG1316	TRANSCRIPTIONal
K8Z41_21250	COG0730	response to heat
K8Z41_21255	COG2210	Belongs to the sulfur carrier protein TusA family
K8Z41_21270	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z41_21275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z41_21275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_21280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K8Z41_21280	COG0425	Belongs to the sulfur carrier protein TusA family
K8Z41_21285	COG1937	Protein conserved in bacteria
K8Z41_21290	COG0446	pyridine nucleotide-disulphide oxidoreductase
K8Z41_21300	COG3591	Belongs to the peptidase S1B family
K8Z41_21310	COG2719	SpoVR family
K8Z41_21315	COG0778	Nitroreductase
K8Z41_21380	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_21385	COG2252	PERMEase
K8Z41_21395	COG1136	(ABC) transporter
K8Z41_21420	COG1846	Transcriptional regulator
K8Z41_21425	COG2814	Major facilitator Superfamily
K8Z41_21430	COG2205	protein histidine kinase activity
K8Z41_21470	COG0351	phosphomethylpyrimidine kinase
K8Z41_21475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K8Z41_21485	COG2104	thiamine diphosphate biosynthetic process
K8Z41_21490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K8Z41_21495	COG0352	thiamine-phosphate diphosphorylase activity
K8Z41_21500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K8Z41_21505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z41_21510	COG1116	anion transmembrane transporter activity
K8Z41_21515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K8Z41_21535	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
K8Z41_21655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z41_21660	COG0581	inorganic phosphate transmembrane transporter activity
K8Z41_21665	COG0573	inorganic phosphate transmembrane transporter activity
K8Z41_21670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K8Z41_21675	COG1918	ferrous iron import across plasma membrane
K8Z41_21675	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z41_21680	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z41_21685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K8Z41_21700	COG0531	amino acid
K8Z41_21705	COG0697	spore germination
K8Z41_21710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K8Z41_21725	COG4990	cell redox homeostasis
K8Z41_21730	COG0833	amino acid
K8Z41_21740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K8Z41_21745	COG1845	cytochrome c oxidase, subunit III
K8Z41_21755	COG0475	glutathione-regulated potassium exporter activity
K8Z41_21755	COG0569	domain protein
K8Z41_21765	COG2153	protein acetylation
K8Z41_21780	COG2252	PERMEase
K8Z41_21785	COG1113	amino acid transport
K8Z41_21800	COG1114	Component of the transport system for branched-chain amino acids
K8Z41_21805	COG3104	oligopeptide transport
K8Z41_21825	COG1476	TRANSCRIPTIONal
K8Z41_21830	COG3583	domain protein
K8Z41_21830	COG3584	3D domain protein
K8Z41_21835	COG0840	transmembrane signaling receptor activity
K8Z41_21880	COG1674	ftsk spoiiie
K8Z41_21980	COG0740	serine-type endopeptidase activity
K8Z41_21990	COG1802	Transcriptional regulator
K8Z41_21990	COG4626	Terminase
K8Z41_22040	COG0582	viral genome integration into host DNA
K8Z41_22130	COG1396	sequence-specific DNA binding
K8Z41_22165	COG1063	alcohol dehydrogenase
K8Z41_22195	COG1879	ABC-type sugar transport system periplasmic component
K8Z41_22200	COG1172	Belongs to the binding-protein-dependent transport system permease family
K8Z41_22215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K8Z41_22220	COG1609	Transcriptional regulator
K8Z41_22225	COG0477	Major facilitator Superfamily
K8Z41_22230	COG1846	Transcriptional regulator
K8Z41_22235	COG2271	Major facilitator Superfamily
K8Z41_22265	COG5002	protein histidine kinase activity
K8Z41_22270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K8Z41_22275	COG2378	regulation of single-species biofilm formation
K8Z41_22285	COG1595	DNA-templated transcription, initiation
K8Z41_22300	COG0833	amino acid
K8Z41_22305	COG0765	amino acid transport
K8Z41_22310	COG0765	amino acid transport
K8Z41_22315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z41_22320	COG1126	abc transporter atp-binding protein
K8Z41_22325	COG1115	amino acid carrier protein
K8Z41_22330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z41_22335	COG0697	spore germination
K8Z41_22350	COG0366	Alpha amylase catalytic
K8Z41_22355	COG1263	PTS System
K8Z41_22355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z41_22360	COG2188	Transcriptional regulator
K8Z41_22365	COG0531	amino acid
K8Z41_22385	COG0714	Associated with various cellular activities
K8Z41_22390	COG4548	von Willebrand factor, type A
K8Z41_22400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z41_22410	COG2226	methyltransferase
K8Z41_22420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_22425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_22430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z41_22435	COG3104	oligopeptide transport
K8Z41_22460	COG1620	l-lactate permease
K8Z41_22465	COG1027	Aspartate ammonia-lyase
K8Z41_22470	COG1253	flavin adenine dinucleotide binding
K8Z41_22475	COG0346	lactoylglutathione lyase activity
K8Z41_22485	COG3344	reverse transcriptase
K8Z41_22495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z41_22500	COG1316	TRANSCRIPTIONal
K8Z41_22505	COG2720	vancomycin resistance protein
K8Z41_22525	COG3227	Zinc metalloprotease (Elastase)
K8Z41_22540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K8Z41_22545	COG2217	Heavy metal translocating P-type atpase
K8Z41_22550	COG0640	Transcriptional regulator
K8Z41_22560	COG0531	amino acid
K8Z41_22575	COG2427	Protein of unknown function (DUF1641)
K8Z41_22580	COG3383	formate dehydrogenase (NAD+) activity
K8Z41_22585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K8Z41_22590	COG0456	acetyltransferase
K8Z41_22590	COG0454	-acetyltransferase
K8Z41_22595	COG0745	RESPONSE REGULATOR receiver
K8Z41_22600	COG5002	protein histidine kinase activity
K8Z41_22610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_22615	COG0697	spore germination
K8Z41_22625	COG0281	malic enzyme
K8Z41_22630	COG3493	citrate carrier protein
K8Z41_22635	COG4565	transcriptional regulatory protein
K8Z41_22640	COG3290	protein histidine kinase activity
K8Z41_22650	COG4990	cell redox homeostasis
K8Z41_22660	COG3850	Histidine kinase
K8Z41_22660	COG5002	protein histidine kinase activity
K8Z41_22665	COG0745	RESPONSE REGULATOR receiver
K8Z41_22670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K8Z41_22680	COG0395	ABC-type sugar transport system, permease component
K8Z41_22685	COG1175	transmembrane transport
K8Z41_22690	COG3842	ATPase activity
K8Z41_22695	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
K8Z41_22720	COG2851	Citrate transporter
K8Z41_22725	COG4565	transcriptional regulatory protein
K8Z41_22730	COG3290	protein histidine kinase activity
K8Z41_22740	COG2268	Band 7 protein
K8Z41_22745	COG1585	Membrane protein implicated in regulation of membrane protease activity
K8Z41_22755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z41_22775	COG2766	serine protein kinase
K8Z41_22780	COG1716	ATPase activity
K8Z41_22780	COG5001	Diguanylate cyclase
K8Z41_22785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K8Z41_22810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K8Z41_22930	COG0735	belongs to the Fur family
K8Z41_22935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K8Z41_22955	COG4555	ABC transporter
K8Z41_22965	COG0067	glutamate synthase
K8Z41_22965	COG0069	glutamate synthase activity
K8Z41_22965	COG0070	glutamate synthase
K8Z41_22970	COG4129	membrane
K8Z41_22975	COG1132	(ABC) transporter
K8Z41_23000	COG1194	a g-specific adenine glycosylase
K8Z41_23005	COG1988	membrane-bound metal-dependent
K8Z41_23035	COG1090	epimerase
K8Z41_23040	COG1228	amidohydrolase
K8Z41_23060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K8Z41_23080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K8Z41_23080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z41_23090	COG0463	Glycosyl transferase, family 2
K8Z41_23105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K8Z41_23110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z41_23110	COG1263	PTS System
K8Z41_23140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K8Z41_23145	COG0833	amino acid
K8Z41_23155	COG3829	transcription factor binding
K8Z41_23170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K8Z41_23175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K8Z41_23195	COG0535	radical SAM domain protein
K8Z41_23205	COG0387	Pfam Sodium calcium exchanger
K8Z41_23210	COG3871	stress protein (general stress protein 26)
K8Z41_23225	COG0586	Pfam SNARE associated Golgi protein
K8Z41_23250	COG2217	Heavy metal translocating P-type atpase
K8Z41_23255	COG1295	ribonuclease BN
K8Z41_23265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K8Z41_23280	COG3853	Toxic anion resistance protein (TelA)
K8Z41_23290	COG0861	Integral membrane protein TerC family
K8Z41_23295	COG2310	stress, protein
K8Z41_23300	COG2310	stress, protein
K8Z41_23305	COG2310	stress, protein
K8Z41_23335	COG2270	Major facilitator Superfamily
K8Z41_23385	COG1116	anion transmembrane transporter activity
K8Z41_23395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K8Z41_23415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K8Z41_23445	COG1263	PTS System
K8Z41_23445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z41_23445	COG2190	(PTS) system
K8Z41_23450	COG0366	Alpha amylase catalytic
K8Z41_23480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z41_23485	COG0549	Belongs to the carbamate kinase family
K8Z41_23510	COG0840	transmembrane signaling receptor activity
K8Z41_23520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K8Z41_23525	COG0765	amino acid transport
K8Z41_23550	COG2814	Major facilitator Superfamily
K8Z41_23555	COG3541	Predicted nucleotidyltransferase
K8Z41_23575	COG5002	protein histidine kinase activity
K8Z41_23600	COG0166	Belongs to the GPI family
K8Z41_23610	COG0492	ferredoxin-NADP+ reductase activity
K8Z41_23615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z41_23620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_23625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_23645	COG0450	alkyl hydroperoxide reductase
K8Z41_23660	COG1473	amidohydrolase
K8Z41_23690	COG4807	Protein conserved in bacteria
K8Z41_23695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z41_23720	COG0730	response to heat
K8Z41_23805	COG0740	serine-type endopeptidase activity
K8Z41_23810	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_23820	COG4626	Terminase
K8Z41_23820	COG1802	Transcriptional regulator
K8Z41_23860	COG0582	viral genome integration into host DNA
K8Z41_23970	COG2002	toxin-antitoxin pair type II binding
K8Z41_23980	COG1484	DNA-dependent DNA replication
K8Z41_24030	COG0582	viral genome integration into host DNA
K8Z41_24040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z41_24055	COG2309	aminopeptidase activity
K8Z41_24065	COG2076	Multidrug Resistance protein
K8Z41_24070	COG1012	belongs to the aldehyde dehydrogenase family
K8Z41_24080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K8Z41_24090	COG1597	lipid kinase activity
K8Z41_24110	COG4682	membrane
K8Z41_24115	COG1846	Transcriptional regulator
K8Z41_24120	COG0003	Pfam Anion-transporting ATPase
K8Z41_24135	COG1464	Belongs to the NlpA lipoprotein family
K8Z41_24140	COG2011	ABC-type metal ion transport system permease component
K8Z41_24150	COG1335	isochorismatase
K8Z41_24165	COG4851	CamS sex pheromone cAM373 precursor
K8Z41_24175	COG0210	DNA helicase
K8Z41_24200	COG0151	Belongs to the GarS family
K8Z41_24210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K8Z41_24220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K8Z41_24235	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K8Z41_24245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K8Z41_24250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K8Z41_24255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K8Z41_24275	COG0463	Glycosyl transferase, family 2
K8Z41_24275	COG1216	Glycosyl transferase, family 2
K8Z41_24285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K8Z41_24340	COG0745	RESPONSE REGULATOR receiver
K8Z41_24345	COG2205	protein histidine kinase activity
K8Z41_24385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K8Z41_24410	COG5002	protein histidine kinase activity
K8Z41_24420	COG2252	PERMEase
K8Z41_24460	COG4824	toxin secretion phage lysis holin
K8Z41_24560	COG0582	viral genome integration into host DNA
K8Z41_24710	COG0582	viral genome integration into host DNA
K8Z41_24775	COG3378	Phage plasmid primase P4 family
K8Z41_24800	COG0582	viral genome integration into host DNA
K8Z41_24815	COG1266	CAAX protease self-immunity
K8Z41_24830	COG0488	(ABC) transporter
K8Z41_24840	COG0456	acetyltransferase
K8Z41_24845	COG1214	PFAM Peptidase M22, glycoprotease
K8Z41_24850	COG0802	atpase or kinase
K8Z41_24950	COG2183	response to ionizing radiation
K8Z41_24955	COG2337	Toxic component of a toxin-antitoxin (TA) module
K8Z41_24960	COG0864	Transcriptional regulator
K8Z41_24965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K8Z41_24970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K8Z41_24980	COG0705	Rhomboid family
K8Z41_24985	COG4294	response to UV
K8Z41_24995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K8Z41_25005	COG2814	Major facilitator Superfamily
K8Z41_25010	COG0531	amino acid
K8Z41_25020	COG0179	Fumarylacetoacetate (FAA) hydrolase
K8Z41_25025	COG3185	4-Hydroxyphenylpyruvate dioxygenase
K8Z41_25055	COG0561	phosphatase activity
K8Z41_25065	COG4608	Belongs to the ABC transporter superfamily
K8Z41_25070	COG0444	Belongs to the ABC transporter superfamily
K8Z41_25075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K8Z41_25090	COG3344	reverse transcriptase
K8Z41_25105	COG0747	negative chemotaxis
K8Z41_25115	COG0488	(ABC) transporter
K8Z41_25135	COG5298	Protein conserved in bacteria
K8Z41_25150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_25160	COG1609	Transcriptional regulator
K8Z41_25170	COG0204	Acyl-transferase
K8Z41_25185	COG0697	spore germination
K8Z41_25200	COG1910	domain protein
K8Z41_25205	COG0725	ABC transporter, periplasmic molybdate-binding protein
K8Z41_25210	COG4149	molybdate abc transporter
K8Z41_25225	COG0656	L-ascorbic acid biosynthetic process
K8Z41_25235	COG4166	transmembrane transport
K8Z41_25240	COG4166	transmembrane transport
K8Z41_25255	COG2207	Transcriptional regulator
K8Z41_25270	COG2814	Major facilitator Superfamily
K8Z41_25280	COG2271	Major facilitator Superfamily
K8Z41_25285	COG0277	FAD linked oxidase domain protein
K8Z41_25295	COG0604	alcohol dehydrogenase
K8Z41_25300	COG1464	Belongs to the NlpA lipoprotein family
K8Z41_25305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K8Z41_25310	COG2011	ABC-type metal ion transport system permease component
K8Z41_25315	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_25350	COG4856	YbbR-like protein
K8Z41_25355	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K8Z41_25435	COG0726	polysaccharide deacetylase
K8Z41_25440	COG2194	sulfuric ester hydrolase activity
K8Z41_25450	COG0489	protein tyrosine kinase activity
K8Z41_25455	COG0860	N-Acetylmuramoyl-L-alanine amidase
K8Z41_25480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K8Z41_25515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K8Z41_25525	COG0024	Methionine aminopeptidase
K8Z41_25535	COG0201	protein transport
K8Z41_25595	COG0255	Belongs to the universal ribosomal protein uL29 family
K8Z41_25660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K8Z41_25665	COG1358	cellular component organization or biogenesis
K8Z41_25680	COG2813	Specifically methylates the guanine in position
K8Z41_25700	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K8Z41_25705	COG0250	Participates in transcription elongation, termination and antitermination
K8Z41_25710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z41_25725	COG3688	RNA-binding protein containing a PIN domain
K8Z41_25730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K8Z41_25745	COG1045	serine acetyltransferase
K8Z41_25765	COG4956	integral membrane protein (PIN domain superfamily)
K8Z41_25775	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K8Z41_25780	COG0542	response to heat
K8Z41_25790	COG3880	PFAM UvrB UvrC protein
K8Z41_25880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K8Z41_25885	COG1396	sequence-specific DNA binding
K8Z41_25890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K8Z41_25895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K8Z41_25900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K8Z41_25905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K8Z41_25910	COG0512	Glutamine amidotransferase of anthranilate synthase
K8Z41_25915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K8Z41_25920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K8Z41_25935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K8Z41_25940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K8Z41_25950	COG2208	phosphoserine phosphatase activity
K8Z41_25965	COG1098	S1 RNA binding domain
K8Z41_25985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K8Z41_25990	COG3956	TIGRFAM MazG family protein
K8Z41_25995	COG2244	polysaccharide biosynthetic process
K8Z41_26000	COG2002	toxin-antitoxin pair type II binding
K8Z41_26005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K8Z41_26025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K8Z41_26035	COG0251	oxidation-reduction process
K8Z41_26040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K8Z41_26055	COG4466	Protein conserved in bacteria
K8Z41_26075	COG0084	hydrolase, TatD family'
K8Z41_26085	COG2002	toxin-antitoxin pair type II binding
K8Z41_26090	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K8Z41_26100	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K8Z41_26110	COG1774	PSP1 C-terminal conserved region
K8Z41_26115	COG0470	DNA polymerase III
K8Z41_26125	COG1982	Orn Lys Arg decarboxylase major
K8Z41_26180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K8Z41_26190	COG0590	tRNA wobble adenosine to inosine editing
K8Z41_26195	COG1335	isochorismatase
K8Z41_26200	COG1428	Deoxynucleoside kinase
K8Z41_26205	COG1428	Deoxynucleoside kinase
K8Z41_26235	COG1686	Belongs to the peptidase S11 family
K8Z41_26240	COG0516	GMP reductase activity
K8Z41_26240	COG0517	IMP dehydrogenase activity
K8Z41_26275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K8Z41_26280	COG0187	DNA topoisomerase II activity
K8Z41_26290	COG2501	S4 domain
K8Z41_26295	COG0592	DNA-directed DNA polymerase activity
K8Z41_26305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K8Z41_26320	COG1847	R3H domain protein
K8Z41_26345	COG1192	Involved in chromosome partitioning
K8Z41_26350	COG1475	DNA binding
K8Z41_26360	COG0668	transmembrane transport
K8Z41_26365	COG4481	Protein conserved in bacteria
K8Z41_26370	COG0012	GTP binding
K8Z41_26390	COG4241	membrane
K8Z41_26395	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
K8Z41_26405	COG0305	Participates in initiation and elongation during chromosome replication
K8Z41_26435	COG0745	RESPONSE REGULATOR receiver
K8Z41_26440	COG5002	protein histidine kinase activity
K8Z41_26450	COG4853	Protein conserved in bacteria
K8Z41_26455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K8Z41_26460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z41_26475	COG5002	protein histidine kinase activity
K8Z41_26510	COG3344	reverse transcriptase
K8Z41_26530	COG1272	protein, Hemolysin III
K8Z41_26535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z41_26555	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
K8Z41_26560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z41_26565	COG2814	Major facilitator Superfamily
K8Z41_26570	COG3275	phosphorelay sensor kinase activity
K8Z41_26590	COG0628	permease
K8Z41_26595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z41_26595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K8Z41_26600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K8Z41_26605	COG1309	transcriptional regulator
K8Z41_26610	COG0488	(ABC) transporter
K8Z41_26615	COG0463	Glycosyl transferase, family 2
K8Z41_26620	COG4485	Bacterial membrane protein, YfhO
K8Z41_26630	COG1216	Glycosyl transferase, family 2
K8Z41_26645	COG1216	Glycosyl transferase, family 2
K8Z41_26650	COG1607	acyl-coa hydrolase
K8Z41_26660	COG0840	transmembrane signaling receptor activity
K8Z41_26675	COG0438	transferase activity, transferring glycosyl groups
K8Z41_26685	COG0477	Major facilitator Superfamily
K8Z41_26690	COG3279	Response regulator of the LytR AlgR family
K8Z41_26695	COG1966	Carbon starvation protein
K8Z41_26700	COG2879	small protein
K8Z41_26705	COG3706	GGDEF domain
K8Z41_26710	COG0351	phosphomethylpyrimidine kinase
K8Z41_26715	COG4585	Histidine kinase
K8Z41_26715	COG2203	Gaf domain
K8Z41_26720	COG2197	response regulator
K8Z41_26730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K8Z41_26735	COG1011	Hydrolase
K8Z41_26745	COG2873	o-acetylhomoserine
K8Z41_26755	COG0460	homoserine dehydrogenase
K8Z41_26765	COG1609	Transcriptional regulator
K8Z41_26770	COG2755	lipolytic protein G-D-S-L family
K8Z41_26775	COG1131	(ABC) transporter
K8Z41_26780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
K8Z41_26790	COG2814	Major facilitator Superfamily
K8Z41_26795	COG0561	phosphatase activity
K8Z41_26800	COG2233	PERMEase
K8Z41_26805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K8Z41_26815	COG2363	Small membrane protein
K8Z41_26825	COG3773	Cell wall hydrolase
K8Z41_26840	COG0280	phosphate acetyltransferase
K8Z41_26860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_26865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K8Z41_26870	COG1120	ATPase activity
K8Z41_26875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K8Z41_26880	COG1078	dGTPase activity
K8Z41_26890	COG1994	Peptidase M50
K8Z41_26900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K8Z41_26905	COG0584	glycerophosphoryl diester phosphodiesterase
K8Z41_26910	COG0789	Transcriptional regulator
K8Z41_26915	COG2814	Major facilitator Superfamily
K8Z41_26940	COG1619	proteins homologs of microcin C7 resistance protein MccF
K8Z41_26945	COG4506	Protein conserved in bacteria
K8Z41_26955	COG1595	DNA-templated transcription, initiation
K8Z41_26980	COG2234	aminopeptidase activity
K8Z41_26990	COG0024	Methionine aminopeptidase
K8Z41_26995	COG1131	(ABC) transporter
K8Z41_27000	COG0842	Transport permease protein
K8Z41_27005	COG4585	Histidine kinase
K8Z41_27010	COG2197	response regulator
K8Z41_27015	COG3227	Zinc metalloprotease (Elastase)
K8Z41_27030	COG5001	Diguanylate cyclase
K8Z41_27030	COG3300	MHYT domain
K8Z41_27045	COG3344	reverse transcriptase
K8Z41_27060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K8Z41_27065	COG0247	lactate metabolic process
K8Z41_27065	COG2181	nitrate reductase activity
K8Z41_27070	COG0183	Belongs to the thiolase family
K8Z41_27075	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z41_27080	COG1960	acyl-CoA dehydrogenase activity
K8Z41_27085	COG1960	acyl-CoA dehydrogenase activity
K8Z41_27095	COG3343	RNA polymerase activity
K8Z41_27105	COG4821	SIS domain
K8Z41_27125	COG1494	fructose-1,6-bisphosphatase
K8Z41_27130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K8Z41_27165	COG0009	L-threonylcarbamoyladenylate synthase
K8Z41_27180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K8Z41_27185	COG2259	Doxx family
K8Z41_27200	COG0698	ribose 5-phosphate isomerase
K8Z41_27235	COG0356	it plays a direct role in the translocation of protons across the membrane
K8Z41_27300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z41_27320	COG0839	Belongs to the complex I subunit 6 family
K8Z41_27330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K8Z41_27335	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K8Z41_27340	COG1007	ATP synthesis coupled electron transport
K8Z41_27345	COG4836	Membrane
K8Z41_27360	COG2385	sporulation resulting in formation of a cellular spore
K8Z41_27365	COG3279	Response regulator of the LytR AlgR family
K8Z41_27380	COG0739	heme binding
K8Z41_27390	COG1609	Transcriptional regulator
K8Z41_27405	COG0489	protein tyrosine kinase activity
K8Z41_27410	COG3944	biosynthesis protein
K8Z41_27415	COG0489	protein tyrosine kinase activity
K8Z41_27420	COG4464	protein tyrosine phosphatase activity
K8Z41_27425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K8Z41_27440	COG1216	Glycosyl transferase, family 2
K8Z41_27450	COG0438	transferase activity, transferring glycosyl groups
K8Z41_27455	COG0463	Glycosyl transferase, family 2
K8Z41_27460	COG1215	transferase activity, transferring glycosyl groups
K8Z41_27465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z41_27470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K8Z41_27475	COG1316	TRANSCRIPTIONal
K8Z41_27485	COG0745	RESPONSE REGULATOR receiver
K8Z41_27490	COG5002	protein histidine kinase activity
K8Z41_27515	COG1136	(ABC) transporter
K8Z41_27520	COG0577	efflux transmembrane transporter activity
K8Z41_27560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K8Z41_27565	COG4715	Zinc finger, swim domain protein
K8Z41_27590	COG1388	LysM domain
K8Z41_27590	COG3584	3D domain protein
K8Z41_27595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K8Z41_27600	COG1215	transferase activity, transferring glycosyl groups
K8Z41_27610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z41_27615	COG1388	LysM domain
K8Z41_27615	COG0791	NLP P60 protein
K8Z41_27625	COG1368	sulfuric ester hydrolase activity
K8Z41_27635	COG2389	metal-binding protein
K8Z41_27650	COG1620	l-lactate permease
K8Z41_27660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K8Z41_27665	COG1294	oxidase, subunit
K8Z41_27670	COG1271	oxidase subunit
K8Z41_27680	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K8Z41_27685	COG0583	DNA-binding transcription factor activity
K8Z41_27690	COG1511	domain protein
K8Z41_27705	COG1301	dicarboxylic acid transport
K8Z41_27710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z41_27720	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z41_27730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K8Z41_27735	COG1447	Phosphotransferase system cellobiose-specific component IIA
K8Z41_27740	COG1486	melibiose metabolic process
K8Z41_27760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K8Z41_27760	COG3933	PFAM sigma-54 factor interaction domain-containing protein
K8Z41_27770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K8Z41_27775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K8Z41_27780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K8Z41_27785	COG1316	TRANSCRIPTIONal
K8Z41_27790	COG1739	Uncharacterized protein family UPF0029
K8Z41_27795	COG1307	EDD domain protein, DegV family
K8Z41_27800	COG1733	regulation of RNA biosynthetic process
K8Z41_27805	COG0791	NLP P60 protein
K8Z41_27805	COG1388	LysM domain
K8Z41_27810	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
K8Z41_27815	COG1040	competence protein
K8Z41_27820	COG1278	Cold shock
K8Z41_27825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K8Z41_27855	COG1131	(ABC) transporter
K8Z41_27880	COG2884	Cell division ATP-binding protein ftsE
K8Z41_27885	COG2177	Part of the ABC transporter FtsEX involved in
K8Z41_27890	COG0793	Belongs to the peptidase S41A family
K8Z41_27890	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_27895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K8Z41_27900	COG1132	(ABC) transporter
K8Z41_27910	COG0488	(ABC) transporter
K8Z41_27915	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z41_27925	COG0583	DNA-binding transcription factor activity
K8Z41_27945	COG0789	Transcriptional regulator
K8Z41_27960	COG0556	nucleotide-excision repair
K8Z41_27965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K8Z41_27975	COG1950	PFAM Membrane protein of
K8Z41_27995	COG0110	maltose O-acetyltransferase activity
K8Z41_28000	COG0457	Tetratricopeptide repeat
K8Z41_28005	COG0492	ferredoxin-NADP+ reductase activity
K8Z41_28015	COG1051	belongs to the nudix hydrolase family
K8Z41_28025	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K8Z41_28035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K8Z41_28045	COG2323	membrane
K8Z41_28060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K8Z41_28085	COG0582	viral genome integration into host DNA
K8Z41_28115	COG3646	Phage regulatory protein
K8Z41_28200	COG3331	DNA recombination
K8Z41_28340	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_28345	COG4824	toxin secretion phage lysis holin
K8Z41_28350	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_28355	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_28355	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_28355	COG1388	LysM domain
K8Z41_28360	COG0457	Tetratricopeptide repeat
K8Z41_28390	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K8Z41_28405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K8Z41_28440	COG1346	cytolysis
K8Z41_28445	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K8Z41_28450	COG1647	Serine aminopeptidase, S33
K8Z41_28455	COG0557	exoribonuclease II activity
K8Z41_28480	COG3344	reverse transcriptase
K8Z41_28495	COG0745	RESPONSE REGULATOR receiver
K8Z41_28540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_28545	COG0488	(ABC) transporter
K8Z41_28600	COG1252	NADH dehydrogenase
K8Z41_28610	COG1733	regulation of RNA biosynthetic process
K8Z41_28615	COG2814	Major facilitator Superfamily
K8Z41_28620	COG0656	L-ascorbic acid biosynthetic process
K8Z41_28635	COG2910	NAD(P)H-binding
K8Z41_28640	COG1115	amino acid carrier protein
K8Z41_28645	COG1115	amino acid carrier protein
K8Z41_28670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K8Z41_28675	COG2311	Membrane
K8Z41_28680	COG1528	Iron-storage protein
K8Z41_28690	COG1611	Belongs to the LOG family
K8Z41_28705	COG0783	Belongs to the Dps family
K8Z41_28710	COG1115	amino acid carrier protein
K8Z41_28715	COG0490	domain, Protein
K8Z41_28720	COG0475	glutathione-regulated potassium exporter activity
K8Z41_28725	COG0586	Pfam SNARE associated Golgi protein
K8Z41_28745	COG3227	Zinc metalloprotease (Elastase)
K8Z41_28750	COG2151	metal-sulfur cluster biosynthetic enzyme
K8Z41_28755	COG0840	transmembrane signaling receptor activity
K8Z41_28785	COG5002	protein histidine kinase activity
K8Z41_28790	COG0745	RESPONSE REGULATOR receiver
K8Z41_28795	COG1376	ErfK ybiS ycfS ynhG family protein
K8Z41_28805	COG0586	Pfam SNARE associated Golgi protein
K8Z41_28840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_28860	COG0531	amino acid
K8Z41_28865	COG2814	Major facilitator Superfamily
K8Z41_28880	COG0840	transmembrane signaling receptor activity
K8Z41_28885	COG0011	TIGRFAM Protein of
K8Z41_28900	COG1686	Belongs to the peptidase S11 family
K8Z41_28910	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z41_28910	COG1024	Enoyl-CoA hydratase
K8Z41_28915	COG0183	Belongs to the thiolase family
K8Z41_28920	COG1960	acyl-CoA dehydrogenase activity
K8Z41_28925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K8Z41_28930	COG1309	transcriptional regulator
K8Z41_28945	COG0039	L-malate dehydrogenase activity
K8Z41_28965	COG1393	Belongs to the ArsC family
K8Z41_28975	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
K8Z41_28980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K8Z41_28995	COG2011	ABC-type metal ion transport system permease component
K8Z41_29000	COG1464	Belongs to the NlpA lipoprotein family
K8Z41_29005	COG1464	Belongs to the NlpA lipoprotein family
K8Z41_29010	COG0396	ATPase activity
K8Z41_29015	COG0719	Fe-S assembly protein
K8Z41_29020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K8Z41_29025	COG0822	iron-sulfur transferase activity
K8Z41_29030	COG0719	Fe-S assembly protein
K8Z41_29035	COG0737	Belongs to the 5'-nucleotidase family
K8Z41_29040	COG3377	Domain of unknown function (DUF1805)
K8Z41_29050	COG0739	heme binding
K8Z41_29075	COG4377	Putative membrane peptidase family (DUF2324)
K8Z41_29080	COG0789	Transcriptional regulator
K8Z41_29090	COG4470	Protein conserved in bacteria
K8Z41_29110	COG1494	fructose-1,6-bisphosphatase
K8Z41_29115	COG2445	Protein of unknown function DUF86
K8Z41_29125	COG0647	UMP catabolic process
K8Z41_29130	COG2249	NAD(P)H dehydrogenase (quinone) activity
K8Z41_29140	COG1358	cellular component organization or biogenesis
K8Z41_29160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K8Z41_29165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K8Z41_29175	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K8Z41_29180	COG4837	Protein of unknown function (DUF1462)
K8Z41_29225	COG2824	Alkylphosphonate utilization operon protein PhnA
K8Z41_29230	COG0390	transport system, permease component
K8Z41_29245	COG1252	NADH dehydrogenase
K8Z41_29260	COG0316	Belongs to the HesB IscA family
K8Z41_29300	COG1396	sequence-specific DNA binding
K8Z41_29395	COG0582	viral genome integration into host DNA
K8Z41_29440	COG4974	Belongs to the 'phage' integrase family
K8Z41_29455	COG3344	reverse transcriptase
K8Z41_29535	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_29585	COG3344	reverse transcriptase
K8Z41_29595	COG3344	reverse transcriptase
K8Z41_29635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_29670	COG2723	6-phospho-beta-galactosidase activity
K8Z41_29675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K8Z41_29675	COG1263	PTS System
K8Z41_29675	COG2190	(PTS) system
K8Z41_29680	COG3711	transcriptional antiterminator
K8Z41_29825	COG3344	reverse transcriptase
K8Z41_29835	COG3344	reverse transcriptase
K8Z41_29970	COG0457	Tetratricopeptide repeat
K8Z41_29980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K8Z41_29985	COG0494	nUDIX hydrolase
K8Z41_29990	COG0542	response to heat
K8Z41_30015	COG1522	sequence-specific DNA binding
K8Z41_30020	COG0288	reversible hydration of carbon dioxide
K8Z41_30025	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
K8Z41_30030	COG2233	PERMEase
K8Z41_30055	COG1687	branched-chain amino acid
K8Z41_30060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K8Z41_30065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K8Z41_30080	COG1361	Conserved repeat domain
K8Z41_30110	COG0741	lytic transglycosylase activity
K8Z41_30115	COG0739	heme binding
K8Z41_30120	COG1388	LysM domain
K8Z41_30120	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_30120	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_30130	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_30280	COG1136	(ABC) transporter
K8Z41_30295	COG1309	transcriptional regulator
K8Z41_30300	COG0367	asparagine synthase
K8Z41_30355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K8Z41_30370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z41_30375	COG0457	Tetratricopeptide repeat
K8Z41_30405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K8Z41_30445	COG0456	acetyltransferase
K8Z41_30445	COG1846	Transcriptional regulator
K8Z41_30455	COG0457	Tetratricopeptide repeat
K8Z41_30465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z41_30505	COG0210	DNA helicase
K8Z41_30520	COG0457	Tetratricopeptide repeat
K8Z41_30555	COG3344	reverse transcriptase
K8Z41_30570	COG1396	sequence-specific DNA binding
K8Z41_30595	COG0667	Aldo Keto reductase
K8Z41_30610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K8Z41_30625	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_30625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z41_30625	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_30625	COG0300	oxidoreductase activity
K8Z41_30625	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_30625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z41_30625	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_30625	COG0300	oxidoreductase activity
K8Z41_30625	COG3321	synthase
K8Z41_30625	COG3321	synthase
K8Z41_30645	COG1960	acyl-CoA dehydrogenase activity
K8Z41_30660	COG1250	3-hydroxyacyl-CoA dehydrogenase
K8Z41_30665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K8Z41_30680	COG0300	oxidoreductase activity
K8Z41_30680	COG3321	synthase
K8Z41_30680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K8Z41_30680	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_30680	COG1028	Short-chain dehydrogenase reductase Sdr
K8Z41_30685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K8Z41_30740	COG1475	DNA binding
K8Z41_30760	COG1132	(ABC) transporter
K8Z41_30810	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_30810	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_30840	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K8Z41_30860	COG1131	(ABC) transporter
K8Z41_30870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K8Z41_30875	COG1132	(ABC) transporter
K8Z41_30945	COG0457	Tetratricopeptide repeat
K8Z41_30975	COG1183	phosphatidylcholine synthase activity
K8Z41_31005	COG5002	protein histidine kinase activity
K8Z41_31005	COG3850	Histidine kinase
K8Z41_31010	COG0745	RESPONSE REGULATOR receiver
K8Z41_31020	COG1136	(ABC) transporter
K8Z41_31025	COG0577	efflux transmembrane transporter activity
K8Z41_31040	COG2814	Major facilitator Superfamily
K8Z41_31065	COG0318	PFAM AMP-dependent synthetase and ligase
K8Z41_31070	COG2259	Doxx family
K8Z41_31105	COG3104	oligopeptide transport
K8Z41_31110	COG1073	alpha beta
K8Z41_31125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K8Z41_31155	COG0659	secondary active sulfate transmembrane transporter activity
K8Z41_31160	COG0589	response to stress
K8Z41_31165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
K8Z41_31175	COG2323	membrane
K8Z41_31180	COG1522	sequence-specific DNA binding
K8Z41_31185	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z41_31235	COG4824	toxin secretion phage lysis holin
K8Z41_31290	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_31290	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_31295	COG0475	glutathione-regulated potassium exporter activity
K8Z41_31300	COG0490	domain, Protein
K8Z41_31305	COG0840	transmembrane signaling receptor activity
K8Z41_31360	COG0583	DNA-binding transcription factor activity
K8Z41_31370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K8Z41_31405	COG0640	Transcriptional regulator
K8Z41_31450	COG0675	Transposase, IS605 OrfB family
K8Z41_31460	COG2828	Protein conserved in bacteria
K8Z41_31495	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z41_31530	COG0457	Tetratricopeptide repeat
K8Z41_31815	COG0592	DNA-directed DNA polymerase activity
K8Z41_31820	COG4712	double-strand break repair protein
K8Z41_31855	COG3344	reverse transcriptase
K8Z41_31865	COG3344	reverse transcriptase
K8Z41_32095	COG3344	reverse transcriptase
K8Z41_32105	COG3344	reverse transcriptase
K8Z41_32160	COG2311	Membrane
K8Z41_32180	COG0457	Tetratricopeptide repeat
K8Z41_32205	COG0583	DNA-binding transcription factor activity
K8Z41_32210	COG0655	NAD(P)H dehydrogenase (quinone) activity
K8Z41_32255	COG0730	response to heat
K8Z41_32280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K8Z41_32310	COG2002	toxin-antitoxin pair type II binding
K8Z41_32315	COG4166	transmembrane transport
K8Z41_32335	COG4974	Belongs to the 'phage' integrase family
K8Z41_32390	COG0653	protein targeting
K8Z41_32405	COG0457	Tetratricopeptide repeat
K8Z41_32435	COG0697	spore germination
K8Z41_32445	COG3344	reverse transcriptase
K8Z41_32470	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K8Z41_32495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K8Z41_32565	COG0791	NLP P60 protein
K8Z41_32565	COG0741	lytic transglycosylase activity
K8Z41_32635	COG2323	membrane
K8Z41_32640	COG1522	sequence-specific DNA binding
K8Z41_32645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K8Z41_32825	COG0457	Tetratricopeptide repeat
K8Z41_32870	COG0739	heme binding
K8Z41_33065	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_33065	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_33105	COG3344	reverse transcriptase
K8Z41_33155	COG1073	alpha beta
K8Z41_33165	COG2197	response regulator
K8Z41_33170	COG1476	TRANSCRIPTIONal
K8Z41_33240	COG3547	Transposase (IS116 IS110 IS902 family)
K8Z41_33300	COG3728	DNA packaging
K8Z41_33300	COG5484	DNA packaging
K8Z41_33400	COG5632	N-Acetylmuramoyl-L-alanine amidase
K8Z41_33400	COG3409	Peptidoglycan-binding domain 1 protein
K8Z41_33400	COG1388	LysM domain
K8Z41_33455	COG1396	sequence-specific DNA binding
K8Z41_33580	COG3331	DNA recombination
K8Z41_33870	COG0457	Tetratricopeptide repeat
K8Z41_33955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K8Z41_33980	COG3654	unkown
K8Z41_34035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair