locus-tag	class	description
BTXL6_00015	COG1309	transcriptional regulator
BTXL6_00045	COG3852	Histidine kinase
BTXL6_00055	COG1285	pathogenesis
BTXL6_00070	COG2514	catechol 2,3-dioxygenase activity
BTXL6_00075	COG2720	vancomycin resistance protein
BTXL6_00105	COG1278	Cold shock
BTXL6_00115	COG0716	FMN binding
BTXL6_00125	COG0494	nUDIX hydrolase
BTXL6_00145	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_00155	COG0165	Argininosuccinate lyase
BTXL6_00170	COG4145	pantothenate transmembrane transporter activity
BTXL6_00180	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_00185	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_00195	COG1657	PFAM Prenyltransferase squalene oxidase
BTXL6_00200	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BTXL6_00205	COG2962	Rard protein
BTXL6_00210	COG3326	Membrane
BTXL6_00225	COG0489	protein tyrosine kinase activity
BTXL6_00235	COG0314	molybdopterin synthase activity
BTXL6_00240	COG0303	'Molybdopterin
BTXL6_00245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTXL6_00250	COG2116	formate transmembrane transporter activity
BTXL6_00260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTXL6_00265	COG5609	conserved protein (DUF2294)
BTXL6_00270	COG2427	Protein of unknown function (DUF1641)
BTXL6_00275	COG3383	formate dehydrogenase (NAD+) activity
BTXL6_00285	COG0697	spore germination
BTXL6_00300	COG0531	amino acid
BTXL6_00335	COG2226	methyltransferase
BTXL6_00340	COG4166	transmembrane transport
BTXL6_00345	COG4166	transmembrane transport
BTXL6_00350	COG4166	transmembrane transport
BTXL6_00360	COG1316	TRANSCRIPTIONal
BTXL6_00370	COG1595	DNA-templated transcription, initiation
BTXL6_00385	COG1131	(ABC) transporter
BTXL6_00405	COG0673	inositol 2-dehydrogenase activity
BTXL6_00410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTXL6_00415	COG0187	DNA topoisomerase II activity
BTXL6_00425	COG1832	CoA-binding protein
BTXL6_00430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTXL6_00435	COG0745	RESPONSE REGULATOR receiver
BTXL6_00455	COG4841	protein insertion into membrane
BTXL6_00460	COG0824	Thioesterase
BTXL6_00490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTXL6_00500	COG2274	protein secretion by the type I secretion system
BTXL6_00505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTXL6_00515	COG0726	polysaccharide deacetylase
BTXL6_00535	COG2211	Major facilitator Superfamily
BTXL6_00545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTXL6_00560	COG0183	Belongs to the thiolase family
BTXL6_00565	COG0318	PFAM AMP-dependent synthetase and ligase
BTXL6_00570	COG1268	BioY protein
BTXL6_00575	COG0318	PFAM AMP-dependent synthetase and ligase
BTXL6_00590	COG1396	sequence-specific DNA binding
BTXL6_00640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_00650	COG5002	protein histidine kinase activity
BTXL6_00655	COG0400	carboxylic ester hydrolase activity
BTXL6_00660	COG0346	lactoylglutathione lyase activity
BTXL6_00665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTXL6_00675	COG0069	glutamate synthase activity
BTXL6_00680	COG1902	pentaerythritol trinitrate reductase activity
BTXL6_00685	COG1329	Transcriptional regulator
BTXL6_00690	COG0010	Belongs to the arginase family
BTXL6_00715	COG2226	methyltransferase
BTXL6_00745	COG4846	Membrane protein involved in cytochrome C biogenesis
BTXL6_00750	COG0785	Cytochrome C biogenesis protein
BTXL6_00770	COG1131	(ABC) transporter
BTXL6_00780	COG0583	DNA-binding transcription factor activity
BTXL6_00790	COG1346	cytolysis
BTXL6_00805	COG0730	response to heat
BTXL6_00815	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTXL6_00815	COG3409	Peptidoglycan-binding domain 1 protein
BTXL6_00830	COG1132	(ABC) transporter
BTXL6_00835	COG1132	(ABC) transporter
BTXL6_00865	COG3639	organic phosphonate transmembrane transporter activity
BTXL6_00875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTXL6_00880	COG0737	Belongs to the 5'-nucleotidase family
BTXL6_00890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BTXL6_00910	COG1695	Transcriptional regulator
BTXL6_00940	COG0174	glutamine synthetase
BTXL6_00945	COG0789	Transcriptional regulator
BTXL6_00950	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BTXL6_00955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTXL6_00960	COG2860	membrane
BTXL6_00970	COG0464	growth
BTXL6_01000	COG1388	LysM domain
BTXL6_01000	COG3584	3D domain protein
BTXL6_01005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTXL6_01005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTXL6_01005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTXL6_01010	COG1105	Belongs to the carbohydrate kinase PfkB family
BTXL6_01015	COG1349	DNA-binding transcription factor activity
BTXL6_01020	COG1979	alcohol dehydrogenase
BTXL6_01025	COG2322	membrane
BTXL6_01040	COG1113	amino acid transport
BTXL6_01050	COG1408	metallophosphoesterase
BTXL6_01055	COG2116	formate transmembrane transporter activity
BTXL6_01070	COG2217	Heavy metal translocating P-type atpase
BTXL6_01075	COG2608	mercury ion transmembrane transporter activity
BTXL6_01080	COG1937	Protein conserved in bacteria
BTXL6_01090	COG2819	hydrolase of the alpha beta superfamily
BTXL6_01095	COG1120	ATPase activity
BTXL6_01100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_01105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_01110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTXL6_01115	COG0708	Exodeoxyribonuclease III
BTXL6_01120	COG2169	Transcriptional regulator
BTXL6_01125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTXL6_01130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTXL6_01140	COG2364	Membrane
BTXL6_01155	COG2267	carboxylic ester hydrolase activity
BTXL6_01160	COG3300	MHYT domain
BTXL6_01160	COG5001	Diguanylate cyclase
BTXL6_01180	COG1086	Polysaccharide biosynthesis protein
BTXL6_01195	COG0384	phenazine biosynthesis protein PhzF
BTXL6_01205	COG1346	cytolysis
BTXL6_01210	COG1380	Effector of murein hydrolase LrgA
BTXL6_01215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_01230	COG1404	Belongs to the peptidase S8 family
BTXL6_01235	COG3773	Cell wall hydrolase
BTXL6_01245	COG1368	sulfuric ester hydrolase activity
BTXL6_01250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTXL6_01260	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BTXL6_01305	COG4550	Control of competence regulator ComK, YlbF/YmcA
BTXL6_01315	COG1013	pyruvate-flavodoxin oxidoreductase activity
BTXL6_01320	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BTXL6_01320	COG0674	pyruvate-flavodoxin oxidoreductase activity
BTXL6_01330	COG2359	stage V sporulation protein S
BTXL6_01335	COG1692	metallophosphoesterase
BTXL6_01360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTXL6_01365	COG1426	Protein conserved in bacteria
BTXL6_01380	COG0300	oxidoreductase activity
BTXL6_01385	COG0612	Peptidase, M16
BTXL6_01390	COG0612	Peptidase, M16
BTXL6_01415	COG2188	Transcriptional regulator
BTXL6_01420	COG1674	ftsk spoiiie
BTXL6_01430	COG0740	serine-type endopeptidase activity
BTXL6_01435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTXL6_01450	COG0527	aspartate kinase activity
BTXL6_01455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTXL6_01460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTXL6_01465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTXL6_01470	COG1873	PFAM PRC-barrel domain
BTXL6_01475	COG0612	Peptidase, M16
BTXL6_01480	COG0726	polysaccharide deacetylase
BTXL6_01495	COG0196	riboflavin kinase activity
BTXL6_01510	COG1550	Protein conserved in bacteria
BTXL6_01520	COG1358	cellular component organization or biogenesis
BTXL6_01525	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BTXL6_01530	COG0195	Participates in both transcription termination and antitermination
BTXL6_01550	COG0750	zinc metalloprotease
BTXL6_01560	COG4589	Belongs to the CDS family
BTXL6_01575	COG0528	UMP kinase activity
BTXL6_01605	COG4974	Belongs to the 'phage' integrase family
BTXL6_01615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTXL6_01620	COG0758	DNA mediated transformation
BTXL6_01625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTXL6_01665	COG1837	Belongs to the UPF0109 family
BTXL6_01675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTXL6_01685	COG0552	protein localization to endoplasmic reticulum
BTXL6_01690	COG1196	nuclear chromosome segregation
BTXL6_01705	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_01710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTXL6_01725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTXL6_01730	COG1461	Dihydroxyacetone kinase
BTXL6_01735	COG1302	Protein conserved in bacteria
BTXL6_01750	COG1564	THIamine pyrophosphokinase
BTXL6_01755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTXL6_01765	COG2815	serine threonine protein kinase
BTXL6_01765	COG0515	serine threonine protein kinase
BTXL6_01770	COG0631	protein serine/threonine phosphatase activity
BTXL6_01780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTXL6_01780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTXL6_01790	COG0242	peptide deformylase activity
BTXL6_01795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTXL6_01800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTXL6_01810	COG0194	GDP metabolic process
BTXL6_01820	COG1561	YicC-like family, N-terminal region
BTXL6_01825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BTXL6_01840	COG0006	proline dipeptidase activity
BTXL6_01855	COG3069	C4-dicarboxylate transmembrane transporter activity
BTXL6_01920	COG0564	pseudouridine synthase activity
BTXL6_01940	COG3599	regulation of cell shape
BTXL6_01945	COG2302	S4 RNA-binding domain
BTXL6_01950	COG0762	integral membrane protein
BTXL6_01960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTXL6_01970	COG1873	PFAM PRC-barrel domain
BTXL6_01975	COG1191	sigma factor activity
BTXL6_01980	COG1191	sigma factor activity
BTXL6_01990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTXL6_01995	COG0849	cell division
BTXL6_02000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BTXL6_02010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BTXL6_02015	COG0772	Belongs to the SEDS family
BTXL6_02030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTXL6_02035	COG0768	penicillin binding
BTXL6_02045	COG4839	cell division protein FtsL
BTXL6_02060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTXL6_02080	COG1399	metal-binding, possibly nucleic acid-binding protein
BTXL6_02090	COG3480	Lon protease (S16) C-terminal proteolytic domain
BTXL6_02095	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTXL6_02100	COG3314	Sporulation integral membrane protein YlbJ
BTXL6_02110	COG0742	ribosomal rna small subunit methyltransferase
BTXL6_02125	COG3679	Belongs to the UPF0342 family
BTXL6_02130	COG0406	alpha-ribazole phosphatase activity
BTXL6_02145	COG2340	Cysteine-rich secretory protein family
BTXL6_02155	COG3336	cytochrome c oxidase
BTXL6_02190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTXL6_02195	COG0772	Belongs to the SEDS family
BTXL6_02205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTXL6_02210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTXL6_02220	COG4896	Protein conserved in bacteria
BTXL6_02245	COG0483	inositol monophosphate 1-phosphatase activity
BTXL6_02265	COG1982	Orn Lys Arg decarboxylase major
BTXL6_02315	COG0022	dehydrogenase e1 component
BTXL6_02320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTXL6_02330	COG0242	peptide deformylase activity
BTXL6_02335	COG0561	phosphatase activity
BTXL6_02345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTXL6_02350	COG0569	domain protein
BTXL6_02370	COG0583	DNA-binding transcription factor activity
BTXL6_02375	COG0517	IMP dehydrogenase activity
BTXL6_02385	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BTXL6_02395	COG4703	Protein of unknown function (DUF1797)
BTXL6_02410	COG2200	EAL domain
BTXL6_02415	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_02420	COG1408	metallophosphoesterase
BTXL6_02430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BTXL6_02470	COG2814	Major facilitator Superfamily
BTXL6_02495	COG3209	COG3209 Rhs family protein
BTXL6_02505	COG2205	protein histidine kinase activity
BTXL6_02515	COG0436	Aminotransferase
BTXL6_02520	COG1609	Transcriptional regulator
BTXL6_02525	COG3833	ABC-type maltose transport systems, permease component
BTXL6_02530	COG1175	transmembrane transport
BTXL6_02535	COG2182	Extracellular solute-binding protein
BTXL6_02545	COG0366	Alpha amylase catalytic
BTXL6_02550	COG3842	ATPase activity
BTXL6_02585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BTXL6_02590	COG0183	Belongs to the thiolase family
BTXL6_02625	COG1695	Transcriptional regulator
BTXL6_02630	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_02645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTXL6_02650	COG0436	Aminotransferase
BTXL6_02685	COG2084	Dehydrogenase
BTXL6_02695	COG2203	Gaf domain
BTXL6_02695	COG2199	diguanylate cyclase activity
BTXL6_02700	COG0778	Nitroreductase
BTXL6_02725	COG1263	PTS System
BTXL6_02725	COG2190	(PTS) system
BTXL6_02725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTXL6_02730	COG3711	transcriptional antiterminator
BTXL6_02750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTXL6_02780	COG1547	Domain of unknown function (DUF309)
BTXL6_02785	COG0456	acetyltransferase
BTXL6_02795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTXL6_02800	COG4086	secreted protein
BTXL6_02805	COG0561	phosphatase activity
BTXL6_02810	COG0697	spore germination
BTXL6_02825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTXL6_02850	COG0733	neurotransmitter:sodium symporter activity
BTXL6_02870	COG1686	Belongs to the peptidase S11 family
BTXL6_02875	COG1725	Transcriptional regulator
BTXL6_02880	COG1131	(ABC) transporter
BTXL6_02905	COG1846	Transcriptional regulator
BTXL6_02920	COG0598	Magnesium transport protein CorA
BTXL6_02945	COG4974	Belongs to the 'phage' integrase family
BTXL6_02955	COG0735	belongs to the Fur family
BTXL6_02960	COG1300	Membrane
BTXL6_02980	COG0667	Aldo Keto reductase
BTXL6_02985	COG0656	L-ascorbic acid biosynthetic process
BTXL6_02990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTXL6_02990	COG0456	acetyltransferase
BTXL6_03000	COG4085	toxin activity
BTXL6_03000	COG0737	Belongs to the 5'-nucleotidase family
BTXL6_03000	COG1525	nuclease
BTXL6_03010	COG0596	Alpha beta hydrolase
BTXL6_03015	COG2056	Na+-H+ antiporter family
BTXL6_03020	COG1609	Transcriptional regulator
BTXL6_03025	COG0456	acetyltransferase
BTXL6_03030	COG1073	alpha beta
BTXL6_03045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTXL6_03045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTXL6_03050	COG0307	riboflavin synthase, alpha
BTXL6_03070	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BTXL6_03075	COG4106	trans-aconitate 2-methyltransferase activity
BTXL6_03080	COG2226	methyltransferase
BTXL6_03080	COG1073	alpha beta
BTXL6_03095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTXL6_03110	COG0737	Belongs to the 5'-nucleotidase family
BTXL6_03120	COG1522	sequence-specific DNA binding
BTXL6_03140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTXL6_03165	COG0300	oxidoreductase activity
BTXL6_03170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_03175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTXL6_03180	COG1760	l-serine dehydratase
BTXL6_03185	COG1760	l-serine dehydratase
BTXL6_03210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BTXL6_03220	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTXL6_03225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_03240	COG1376	ErfK ybiS ycfS ynhG family protein
BTXL6_03245	COG4129	membrane
BTXL6_03250	COG1126	abc transporter atp-binding protein
BTXL6_03255	COG0765	amino acid transport
BTXL6_03260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTXL6_03280	COG2323	membrane
BTXL6_03285	COG0772	Belongs to the SEDS family
BTXL6_03295	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTXL6_03300	COG0022	dehydrogenase e1 component
BTXL6_03305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTXL6_03310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTXL6_03320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTXL6_03325	COG0280	phosphate acetyltransferase
BTXL6_03335	COG3290	protein histidine kinase activity
BTXL6_03335	COG3829	transcription factor binding
BTXL6_03345	COG0584	glycerophosphoryl diester phosphodiesterase
BTXL6_03350	COG3093	addiction module antidote protein HigA
BTXL6_03360	COG0745	RESPONSE REGULATOR receiver
BTXL6_03370	COG0750	zinc metalloprotease
BTXL6_03375	COG0497	DNA recombination
BTXL6_03385	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTXL6_03395	COG0142	geranyltranstransferase activity
BTXL6_03420	COG1302	Protein conserved in bacteria
BTXL6_03425	COG0439	Biotin carboxylase
BTXL6_03430	COG0511	ligase activity, forming carbon-carbon bonds
BTXL6_03475	COG3854	ATPases associated with a variety of cellular activities
BTXL6_03500	COG0006	proline dipeptidase activity
BTXL6_03515	COG3872	metal-dependent enzyme
BTXL6_03525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTXL6_03560	COG0095	Lipoate-protein ligase
BTXL6_03565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTXL6_03575	COG1609	Transcriptional regulator
BTXL6_03585	COG2076	Multidrug Resistance protein
BTXL6_03590	COG2076	Multidrug Resistance protein
BTXL6_03635	COG1725	Transcriptional regulator
BTXL6_03665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTXL6_03760	COG4824	toxin secretion phage lysis holin
BTXL6_03830	COG0740	serine-type endopeptidase activity
BTXL6_03840	COG4626	Terminase
BTXL6_03840	COG1802	Transcriptional regulator
BTXL6_03875	COG0582	viral genome integration into host DNA
BTXL6_03880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BTXL6_03940	COG2002	toxin-antitoxin pair type II binding
BTXL6_04015	COG4970	Tfp pilus assembly protein FimT
BTXL6_04025	COG1459	type II secretion system
BTXL6_04030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTXL6_04080	COG0646	methionine synthase
BTXL6_04080	COG1410	methionine synthase
BTXL6_04085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTXL6_04085	COG0646	methionine synthase
BTXL6_04090	COG0626	cystathionine gamma-synthase activity
BTXL6_04095	COG0626	cystathionine gamma-synthase activity
BTXL6_04115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_04125	COG1940	carbohydrate kinase activity
BTXL6_04130	COG4483	Protein conserved in bacteria
BTXL6_04135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTXL6_04145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTXL6_04150	COG0704	Plays a role in the regulation of phosphate uptake
BTXL6_04155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTXL6_04160	COG0581	inorganic phosphate transmembrane transporter activity
BTXL6_04165	COG0573	inorganic phosphate transmembrane transporter activity
BTXL6_04170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTXL6_04180	COG0477	Major facilitator Superfamily
BTXL6_04185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTXL6_04215	COG0735	belongs to the Fur family
BTXL6_04220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTXL6_04225	COG1121	(ABC) transporter
BTXL6_04230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_04260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTXL6_04265	COG2384	SAM-dependent methyltransferase
BTXL6_04270	COG2010	Cytochrome c
BTXL6_04275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTXL6_04280	COG0358	DNA primase activity
BTXL6_04300	COG0517	IMP dehydrogenase activity
BTXL6_04315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTXL6_04320	COG0295	cytidine deaminase activity
BTXL6_04325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTXL6_04335	COG1480	7TM receptor with intracellular HD hydrolase
BTXL6_04340	COG1702	phosphate starvation-inducible protein PhoH
BTXL6_04360	COG1610	YqeY-like protein
BTXL6_04370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTXL6_04375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTXL6_04405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTXL6_04410	COG1733	regulation of RNA biosynthetic process
BTXL6_04435	COG1466	dna polymerase III delta subunit
BTXL6_04445	COG0658	competence protein
BTXL6_04445	COG2333	competence protein COMEC
BTXL6_04450	COG2131	deaminase
BTXL6_04455	COG1555	photosystem II stabilization
BTXL6_04455	COG1596	polysaccharide export
BTXL6_04460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTXL6_04465	COG2226	methyltransferase
BTXL6_04470	COG0799	negative regulation of ribosome biogenesis
BTXL6_04475	COG1713	HD superfamily hydrolase involved in NAD metabolism
BTXL6_04485	COG1534	Rna-binding protein
BTXL6_04495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTXL6_04500	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BTXL6_04515	COG1191	sigma factor activity
BTXL6_04530	COG0778	Nitroreductase
BTXL6_04535	COG2357	RelA SpoT domain protein
BTXL6_04545	COG1785	Belongs to the alkaline phosphatase family
BTXL6_04555	COG2267	carboxylic ester hydrolase activity
BTXL6_04590	COG1404	Belongs to the peptidase S8 family
BTXL6_04595	COG3186	Phenylalanine-4-hydroxylase
BTXL6_04605	COG2514	catechol 2,3-dioxygenase activity
BTXL6_04610	COG2259	Doxx family
BTXL6_04650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTXL6_04660	COG1454	alcohol dehydrogenase
BTXL6_04660	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_04665	COG0626	cystathionine gamma-synthase activity
BTXL6_04670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTXL6_04695	COG0768	penicillin binding
BTXL6_04725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTXL6_04755	COG0628	permease
BTXL6_04775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTXL6_04790	COG1104	cysteine desulfurase activity
BTXL6_04795	COG1959	2 iron, 2 sulfur cluster binding
BTXL6_04800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTXL6_04815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTXL6_04840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTXL6_04850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BTXL6_04850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTXL6_04855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTXL6_04860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTXL6_04860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTXL6_04870	COG2244	polysaccharide biosynthetic process
BTXL6_04875	COG2323	membrane
BTXL6_04885	COG1862	Preprotein translocase
BTXL6_04915	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BTXL6_04925	COG0697	spore germination
BTXL6_04930	COG0640	Transcriptional regulator
BTXL6_04955	COG0157	Belongs to the NadC ModD family
BTXL6_04960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTXL6_04965	COG1104	cysteine desulfurase activity
BTXL6_04970	COG1827	regulation of RNA biosynthetic process
BTXL6_04975	COG2258	MOSC domain
BTXL6_04980	COG0077	Prephenate dehydratase
BTXL6_04985	COG0577	efflux transmembrane transporter activity
BTXL6_04990	COG0577	efflux transmembrane transporter activity
BTXL6_04995	COG1136	(ABC) transporter
BTXL6_05000	COG5002	protein histidine kinase activity
BTXL6_05005	COG0745	RESPONSE REGULATOR receiver
BTXL6_05015	COG3290	protein histidine kinase activity
BTXL6_05025	COG2868	ribosomal protein
BTXL6_05035	COG1530	ribonuclease E activity
BTXL6_05040	COG1994	Peptidase M50
BTXL6_05045	COG0739	heme binding
BTXL6_05050	COG2894	cell division
BTXL6_05065	COG1792	Involved in formation and maintenance of cell shape
BTXL6_05070	COG1077	Cell shape determining protein MreB Mrl
BTXL6_05090	COG0285	dihydrofolate synthase activity
BTXL6_05105	COG1388	LysM domain
BTXL6_05115	COG0113	porphobilinogen synthase activity
BTXL6_05120	COG1587	Uroporphyrinogen-III synthase
BTXL6_05130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTXL6_05140	COG1846	Transcriptional regulator
BTXL6_05145	COG1764	response to oxidative stress
BTXL6_05160	COG1067	ATP-dependent peptidase activity
BTXL6_05160	COG0470	DNA polymerase III
BTXL6_05210	COG0622	Phosphoesterase
BTXL6_05215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BTXL6_05225	COG5401	PFAM Sporulation and spore germination
BTXL6_05245	COG1309	transcriptional regulator
BTXL6_05260	COG2197	response regulator
BTXL6_05265	COG2233	PERMEase
BTXL6_05275	COG0402	S-adenosylhomocysteine deaminase activity
BTXL6_05280	COG0402	S-adenosylhomocysteine deaminase activity
BTXL6_05300	COG0444	Belongs to the ABC transporter superfamily
BTXL6_05305	COG4608	Belongs to the ABC transporter superfamily
BTXL6_05310	COG3275	phosphorelay sensor kinase activity
BTXL6_05315	COG3279	Response regulator of the LytR AlgR family
BTXL6_05325	COG1983	PspC domain protein
BTXL6_05330	COG1396	sequence-specific DNA binding
BTXL6_05335	COG0697	spore germination
BTXL6_05345	COG1959	2 iron, 2 sulfur cluster binding
BTXL6_05350	COG1668	transmembrane transport
BTXL6_05355	COG4152	abc transporter atp-binding protein
BTXL6_05360	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BTXL6_05365	COG1360	Flagellar Motor Protein
BTXL6_05370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTXL6_05375	COG1876	peptidase activity
BTXL6_05380	COG0824	Thioesterase
BTXL6_05385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTXL6_05390	COG1053	succinate dehydrogenase
BTXL6_05395	COG2009	succinate dehydrogenase
BTXL6_05400	COG1719	4-vinyl reductase, 4VR
BTXL6_05410	COG3118	belongs to the thioredoxin family
BTXL6_05415	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BTXL6_05420	COG2086	electron transfer activity
BTXL6_05425	COG1024	Enoyl-CoA hydratase
BTXL6_05430	COG1309	transcriptional regulator
BTXL6_05435	COG0318	PFAM AMP-dependent synthetase and ligase
BTXL6_05445	COG2318	DinB family
BTXL6_05475	COG1131	(ABC) transporter
BTXL6_05480	COG2205	protein histidine kinase activity
BTXL6_05485	COG0745	RESPONSE REGULATOR receiver
BTXL6_05495	COG4895	conserved protein (DUF2196)
BTXL6_05500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTXL6_05510	COG4509	Sortase family
BTXL6_05515	COG1120	ATPase activity
BTXL6_05530	COG5386	Cell surface protein
BTXL6_05540	COG5386	Cell surface protein
BTXL6_05545	COG1114	Component of the transport system for branched-chain amino acids
BTXL6_05550	COG1187	pseudouridine synthase activity
BTXL6_05565	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTXL6_05565	COG1796	DNA polymerase
BTXL6_05570	COG1286	toxin biosynthetic process
BTXL6_05600	COG0017	Asparaginyl-tRNA synthetase
BTXL6_05615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTXL6_05625	COG1418	mRNA catabolic process
BTXL6_05635	COG2814	Major facilitator Superfamily
BTXL6_05640	COG1566	PFAM secretion protein HlyD family protein
BTXL6_05645	COG1309	transcriptional regulator
BTXL6_05650	COG1363	Peptidase, m42
BTXL6_05670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BTXL6_05675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTXL6_05685	COG1484	DNA-dependent DNA replication
BTXL6_05690	COG3611	Membrane attachment protein
BTXL6_05700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BTXL6_05705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTXL6_05710	COG0237	dephospho-CoA kinase activity
BTXL6_05715	COG1971	Probably functions as a manganese efflux pump
BTXL6_05725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTXL6_05725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTXL6_05730	COG5002	protein histidine kinase activity
BTXL6_05735	COG0745	RESPONSE REGULATOR receiver
BTXL6_05755	COG0538	isocitrate dehydrogenase activity
BTXL6_05760	COG0372	Belongs to the citrate synthase family
BTXL6_05775	COG0628	permease
BTXL6_05780	COG3030	protein affecting phage T7 exclusion by the F plasmid
BTXL6_05805	COG1725	Transcriptional regulator
BTXL6_05810	COG0281	malic enzyme
BTXL6_05815	COG0587	DNA-directed DNA polymerase activity
BTXL6_05830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTXL6_05845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTXL6_05855	COG4109	DRTGG domain
BTXL6_05870	COG0006	proline dipeptidase activity
BTXL6_05905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_05910	COG0662	Cupin 2, conserved barrel domain protein
BTXL6_05920	COG1476	TRANSCRIPTIONal
BTXL6_05935	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_05940	COG0589	response to stress
BTXL6_05975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_06000	COG0827	DNA restriction-modification system
BTXL6_06005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BTXL6_06010	COG3874	Sporulation protein YtfJ
BTXL6_06020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BTXL6_06025	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BTXL6_06035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTXL6_06050	COG1104	cysteine desulfurase activity
BTXL6_06060	COG0583	DNA-binding transcription factor activity
BTXL6_06065	COG0697	spore germination
BTXL6_06070	COG1309	transcriptional regulator
BTXL6_06075	COG1956	GAF domain-containing protein
BTXL6_06080	COG0626	cystathionine gamma-synthase activity
BTXL6_06100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTXL6_06110	COG1595	DNA-templated transcription, initiation
BTXL6_06125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTXL6_06130	COG0454	-acetyltransferase
BTXL6_06135	COG0517	IMP dehydrogenase activity
BTXL6_06140	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTXL6_06145	COG2267	carboxylic ester hydrolase activity
BTXL6_06155	COG0745	RESPONSE REGULATOR receiver
BTXL6_06160	COG5002	protein histidine kinase activity
BTXL6_06165	COG0666	response to abiotic stimulus
BTXL6_06200	COG1609	Transcriptional regulator
BTXL6_06210	COG4851	CamS sex pheromone cAM373 precursor
BTXL6_06215	COG3118	belongs to the thioredoxin family
BTXL6_06225	COG2309	aminopeptidase activity
BTXL6_06240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_06245	COG0697	spore germination
BTXL6_06250	COG0789	Transcriptional regulator
BTXL6_06255	COG1695	Transcriptional regulator
BTXL6_06275	COG1674	ftsk spoiiie
BTXL6_06290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTXL6_06300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTXL6_06305	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BTXL6_06310	COG1363	Peptidase, m42
BTXL6_06320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_06335	COG0510	thiamine kinase activity
BTXL6_06340	COG1523	belongs to the glycosyl hydrolase 13 family
BTXL6_06355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTXL6_06360	COG1349	DNA-binding transcription factor activity
BTXL6_06365	COG1187	pseudouridine synthase activity
BTXL6_06370	COG2244	polysaccharide biosynthetic process
BTXL6_06375	COG2081	HI0933 family
BTXL6_06380	COG2814	Major facilitator Superfamily
BTXL6_06390	COG3832	glyoxalase III activity
BTXL6_06410	COG1329	Transcriptional regulator
BTXL6_06435	COG0314	molybdopterin synthase activity
BTXL6_06440	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTXL6_06445	COG0303	'Molybdopterin
BTXL6_06455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTXL6_06460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTXL6_06480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTXL6_06490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTXL6_06530	COG2814	Major facilitator Superfamily
BTXL6_06535	COG0475	glutathione-regulated potassium exporter activity
BTXL6_06540	COG0490	domain, Protein
BTXL6_06545	COG0582	viral genome integration into host DNA
BTXL6_06555	COG1136	(ABC) transporter
BTXL6_06575	COG1242	4 iron, 4 sulfur cluster binding
BTXL6_06580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BTXL6_06595	COG1794	racemase activity, acting on amino acids and derivatives
BTXL6_06620	COG2267	carboxylic ester hydrolase activity
BTXL6_06625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTXL6_06630	COG0671	phosphoesterase, PA-phosphatase related
BTXL6_06635	COG0438	transferase activity, transferring glycosyl groups
BTXL6_06645	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTXL6_06660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_06725	COG5002	protein histidine kinase activity
BTXL6_06730	COG4191	Histidine kinase
BTXL6_06735	COG2267	carboxylic ester hydrolase activity
BTXL6_06740	COG1368	sulfuric ester hydrolase activity
BTXL6_06755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTXL6_06760	COG1116	anion transmembrane transporter activity
BTXL6_06765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTXL6_06790	COG0494	nUDIX hydrolase
BTXL6_06825	COG0288	reversible hydration of carbon dioxide
BTXL6_06830	COG1271	oxidase subunit
BTXL6_06835	COG1294	oxidase, subunit
BTXL6_06860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_06885	COG1842	Phage shock protein A
BTXL6_06920	COG5002	protein histidine kinase activity
BTXL6_06925	COG0745	RESPONSE REGULATOR receiver
BTXL6_06955	COG1597	lipid kinase activity
BTXL6_06970	COG0577	efflux transmembrane transporter activity
BTXL6_06995	COG0586	Pfam SNARE associated Golgi protein
BTXL6_07015	COG0577	efflux transmembrane transporter activity
BTXL6_07020	COG1136	(ABC) transporter
BTXL6_07025	COG3708	Transcriptional regulator
BTXL6_07025	COG2207	Transcriptional regulator
BTXL6_07030	COG5658	integral membrane protein
BTXL6_07035	COG0640	Transcriptional regulator
BTXL6_07040	COG0745	RESPONSE REGULATOR receiver
BTXL6_07045	COG2205	protein histidine kinase activity
BTXL6_07050	COG0577	efflux transmembrane transporter activity
BTXL6_07055	COG0577	efflux transmembrane transporter activity
BTXL6_07060	COG1136	(ABC) transporter
BTXL6_07065	COG0577	efflux transmembrane transporter activity
BTXL6_07110	COG3964	amidohydrolase
BTXL6_07130	COG4948	Mandelate Racemase Muconate Lactonizing
BTXL6_07145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTXL6_07150	COG0596	Alpha beta hydrolase
BTXL6_07160	COG1169	isochorismate synthase
BTXL6_07165	COG1575	Belongs to the MenA family. Type 1 subfamily
BTXL6_07170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTXL6_07175	COG1278	Cold shock
BTXL6_07200	COG0058	SHG alpha-glucan phosphorylase activity
BTXL6_07210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTXL6_07230	COG1404	Belongs to the peptidase S8 family
BTXL6_07235	COG0039	L-malate dehydrogenase activity
BTXL6_07340	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTXL6_07375	COG1285	pathogenesis
BTXL6_07380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTXL6_07400	COG2155	Conserved Protein
BTXL6_07405	COG1098	S1 RNA binding domain
BTXL6_07410	COG0436	Aminotransferase
BTXL6_07415	COG1522	sequence-specific DNA binding
BTXL6_07420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTXL6_07425	COG2267	carboxylic ester hydrolase activity
BTXL6_07435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BTXL6_07455	COG5018	Exonuclease
BTXL6_07460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTXL6_07475	COG0423	glycine-tRNA ligase activity
BTXL6_07480	COG2050	protein possibly involved in aromatic compounds catabolism
BTXL6_07490	COG1268	BioY protein
BTXL6_07495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTXL6_07500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTXL6_07515	COG3584	3D domain protein
BTXL6_07530	COG1252	NADH dehydrogenase
BTXL6_07540	COG3708	Transcriptional regulator
BTXL6_07555	COG1683	Conserved Protein
BTXL6_07575	COG0316	Belongs to the HesB IscA family
BTXL6_07590	COG1252	NADH dehydrogenase
BTXL6_07605	COG0390	transport system, permease component
BTXL6_07610	COG2824	Alkylphosphonate utilization operon protein PhnA
BTXL6_07630	COG4837	Protein of unknown function (DUF1462)
BTXL6_07635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTXL6_07645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTXL6_07650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTXL6_07665	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTXL6_07670	COG0647	UMP catabolic process
BTXL6_07680	COG2445	Protein of unknown function DUF86
BTXL6_07685	COG1494	fructose-1,6-bisphosphatase
BTXL6_07705	COG4470	Protein conserved in bacteria
BTXL6_07715	COG0789	Transcriptional regulator
BTXL6_07720	COG4377	Putative membrane peptidase family (DUF2324)
BTXL6_07745	COG0739	heme binding
BTXL6_07755	COG3377	Domain of unknown function (DUF1805)
BTXL6_07760	COG0737	Belongs to the 5'-nucleotidase family
BTXL6_07765	COG1695	Transcriptional regulator
BTXL6_07775	COG0719	Fe-S assembly protein
BTXL6_07780	COG0822	iron-sulfur transferase activity
BTXL6_07785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTXL6_07790	COG0719	Fe-S assembly protein
BTXL6_07795	COG0396	ATPase activity
BTXL6_07800	COG1464	Belongs to the NlpA lipoprotein family
BTXL6_07805	COG1464	Belongs to the NlpA lipoprotein family
BTXL6_07810	COG2011	ABC-type metal ion transport system permease component
BTXL6_07815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTXL6_07825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTXL6_07830	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BTXL6_07840	COG1393	Belongs to the ArsC family
BTXL6_07905	COG1309	transcriptional regulator
BTXL6_07910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_07915	COG1960	acyl-CoA dehydrogenase activity
BTXL6_07920	COG0183	Belongs to the thiolase family
BTXL6_07925	COG1024	Enoyl-CoA hydratase
BTXL6_07925	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTXL6_07935	COG1686	Belongs to the peptidase S11 family
BTXL6_07950	COG0011	TIGRFAM Protein of
BTXL6_07955	COG0840	transmembrane signaling receptor activity
BTXL6_07975	COG2814	Major facilitator Superfamily
BTXL6_07980	COG0531	amino acid
BTXL6_08005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_08040	COG0586	Pfam SNARE associated Golgi protein
BTXL6_08050	COG1376	ErfK ybiS ycfS ynhG family protein
BTXL6_08055	COG0745	RESPONSE REGULATOR receiver
BTXL6_08060	COG5002	protein histidine kinase activity
BTXL6_08085	COG0840	transmembrane signaling receptor activity
BTXL6_08090	COG2151	metal-sulfur cluster biosynthetic enzyme
BTXL6_08095	COG3227	Zinc metalloprotease (Elastase)
BTXL6_08100	COG1741	Belongs to the pirin family
BTXL6_08115	COG0586	Pfam SNARE associated Golgi protein
BTXL6_08120	COG0475	glutathione-regulated potassium exporter activity
BTXL6_08125	COG0490	domain, Protein
BTXL6_08135	COG1115	amino acid carrier protein
BTXL6_08140	COG0783	Belongs to the Dps family
BTXL6_08155	COG1611	Belongs to the LOG family
BTXL6_08175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTXL6_08180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTXL6_08185	COG1115	amino acid carrier protein
BTXL6_08190	COG1115	amino acid carrier protein
BTXL6_08195	COG2910	NAD(P)H-binding
BTXL6_08210	COG0656	L-ascorbic acid biosynthetic process
BTXL6_08215	COG2814	Major facilitator Superfamily
BTXL6_08220	COG1733	regulation of RNA biosynthetic process
BTXL6_08230	COG1252	NADH dehydrogenase
BTXL6_08235	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTXL6_08250	COG0840	transmembrane signaling receptor activity
BTXL6_08250	COG3290	protein histidine kinase activity
BTXL6_08260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BTXL6_08280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_08285	COG3223	Belongs to the PsiE family
BTXL6_08345	COG5002	protein histidine kinase activity
BTXL6_08350	COG0745	RESPONSE REGULATOR receiver
BTXL6_08355	COG1136	(ABC) transporter
BTXL6_08375	COG1136	(ABC) transporter
BTXL6_08400	COG0557	exoribonuclease II activity
BTXL6_08405	COG1647	Serine aminopeptidase, S33
BTXL6_08410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTXL6_08415	COG1346	cytolysis
BTXL6_08450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTXL6_08465	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTXL6_08490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTXL6_08505	COG2323	membrane
BTXL6_08515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTXL6_08525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BTXL6_08535	COG1051	belongs to the nudix hydrolase family
BTXL6_08545	COG0492	ferredoxin-NADP+ reductase activity
BTXL6_08550	COG0457	Tetratricopeptide repeat
BTXL6_08555	COG0110	maltose O-acetyltransferase activity
BTXL6_08575	COG1950	PFAM Membrane protein of
BTXL6_08585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTXL6_08590	COG0556	nucleotide-excision repair
BTXL6_08605	COG0789	Transcriptional regulator
BTXL6_08625	COG0583	DNA-binding transcription factor activity
BTXL6_08635	COG0655	NAD(P)H dehydrogenase (quinone) activity
BTXL6_08650	COG1132	(ABC) transporter
BTXL6_08655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTXL6_08660	COG3409	Peptidoglycan-binding domain 1 protein
BTXL6_08660	COG0793	Belongs to the peptidase S41A family
BTXL6_08665	COG2177	Part of the ABC transporter FtsEX involved in
BTXL6_08670	COG2884	Cell division ATP-binding protein ftsE
BTXL6_08680	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BTXL6_08690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTXL6_08695	COG1278	Cold shock
BTXL6_08700	COG1040	competence protein
BTXL6_08705	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BTXL6_08710	COG1388	LysM domain
BTXL6_08710	COG0791	NLP P60 protein
BTXL6_08715	COG1733	regulation of RNA biosynthetic process
BTXL6_08725	COG1307	EDD domain protein, DegV family
BTXL6_08730	COG1739	Uncharacterized protein family UPF0029
BTXL6_08735	COG1316	TRANSCRIPTIONal
BTXL6_08740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BTXL6_08745	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BTXL6_08750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTXL6_08760	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BTXL6_08760	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BTXL6_08780	COG1486	melibiose metabolic process
BTXL6_08785	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTXL6_08790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTXL6_08810	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTXL6_08820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTXL6_08825	COG1301	dicarboxylic acid transport
BTXL6_08835	COG0346	lactoylglutathione lyase activity
BTXL6_08840	COG1511	domain protein
BTXL6_08845	COG0583	DNA-binding transcription factor activity
BTXL6_08850	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BTXL6_08860	COG1271	oxidase subunit
BTXL6_08865	COG1294	oxidase, subunit
BTXL6_08875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTXL6_08885	COG1620	l-lactate permease
BTXL6_08895	COG2389	metal-binding protein
BTXL6_08905	COG1368	sulfuric ester hydrolase activity
BTXL6_08915	COG0791	NLP P60 protein
BTXL6_08915	COG1388	LysM domain
BTXL6_08920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTXL6_08930	COG1215	transferase activity, transferring glycosyl groups
BTXL6_08940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTXL6_08945	COG1388	LysM domain
BTXL6_08945	COG3584	3D domain protein
BTXL6_08970	COG4715	Zinc finger, swim domain protein
BTXL6_08975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTXL6_09005	COG1191	sigma factor activity
BTXL6_09015	COG0577	efflux transmembrane transporter activity
BTXL6_09020	COG1136	(ABC) transporter
BTXL6_09045	COG5002	protein histidine kinase activity
BTXL6_09050	COG0745	RESPONSE REGULATOR receiver
BTXL6_09055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTXL6_09080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTXL6_09085	COG1134	teichoic acid transport
BTXL6_09090	COG1682	transport, permease protein
BTXL6_09095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BTXL6_09110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BTXL6_09115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BTXL6_09120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BTXL6_09130	COG1609	Transcriptional regulator
BTXL6_09140	COG0739	heme binding
BTXL6_09155	COG3279	Response regulator of the LytR AlgR family
BTXL6_09160	COG2385	sporulation resulting in formation of a cellular spore
BTXL6_09165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTXL6_09175	COG4836	Membrane
BTXL6_09180	COG1007	ATP synthesis coupled electron transport
BTXL6_09185	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTXL6_09190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTXL6_09200	COG0839	Belongs to the complex I subunit 6 family
BTXL6_09220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTXL6_09235	COG3300	MHYT domain
BTXL6_09235	COG5001	Diguanylate cyclase
BTXL6_09285	COG0356	it plays a direct role in the translocation of protons across the membrane
BTXL6_09320	COG0698	ribose 5-phosphate isomerase
BTXL6_09330	COG2190	(PTS) system
BTXL6_09335	COG2259	Doxx family
BTXL6_09340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTXL6_09355	COG0009	L-threonylcarbamoyladenylate synthase
BTXL6_09370	COG2890	protein-(glutamine-N5) methyltransferase activity
BTXL6_09375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTXL6_09390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTXL6_09395	COG1494	fructose-1,6-bisphosphatase
BTXL6_09400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTXL6_09415	COG4821	SIS domain
BTXL6_09435	COG1960	acyl-CoA dehydrogenase activity
BTXL6_09440	COG1960	acyl-CoA dehydrogenase activity
BTXL6_09445	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTXL6_09450	COG0183	Belongs to the thiolase family
BTXL6_09455	COG2181	nitrate reductase activity
BTXL6_09455	COG0247	lactate metabolic process
BTXL6_09460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTXL6_09470	COG3300	MHYT domain
BTXL6_09470	COG5001	Diguanylate cyclase
BTXL6_09490	COG2197	response regulator
BTXL6_09495	COG4585	Histidine kinase
BTXL6_09500	COG0842	Transport permease protein
BTXL6_09505	COG1131	(ABC) transporter
BTXL6_09510	COG0024	Methionine aminopeptidase
BTXL6_09515	COG2234	aminopeptidase activity
BTXL6_09545	COG1595	DNA-templated transcription, initiation
BTXL6_09555	COG4506	Protein conserved in bacteria
BTXL6_09560	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTXL6_09585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BTXL6_09590	COG2814	Major facilitator Superfamily
BTXL6_09620	COG0470	DNA polymerase III
BTXL6_09665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTXL6_09705	COG0457	Tetratricopeptide repeat
BTXL6_09780	COG2002	toxin-antitoxin pair type II binding
BTXL6_09785	COG0653	protein targeting
BTXL6_09790	COG0582	viral genome integration into host DNA
BTXL6_09860	COG1466	dna polymerase III delta subunit
BTXL6_09900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTXL6_10000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTXL6_10030	COG2197	response regulator
BTXL6_10035	COG5002	protein histidine kinase activity
BTXL6_10040	COG1073	alpha beta
BTXL6_10235	COG0305	Participates in initiation and elongation during chromosome replication
BTXL6_10365	COG0592	DNA-directed DNA polymerase activity
BTXL6_10430	COG0791	NLP P60 protein
BTXL6_10430	COG1388	LysM domain
BTXL6_10530	COG3300	MHYT domain
BTXL6_10530	COG5001	Diguanylate cyclase
BTXL6_10555	COG2124	cytochrome p450
BTXL6_10560	COG1846	Transcriptional regulator
BTXL6_10565	COG1846	Transcriptional regulator
BTXL6_10570	COG2814	Major facilitator Superfamily
BTXL6_10600	COG0475	glutathione-regulated potassium exporter activity
BTXL6_10650	COG3335	DDE superfamily endonuclease
BTXL6_10675	COG0697	spore germination
BTXL6_10730	COG0464	growth
BTXL6_10735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTXL6_10845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BTXL6_10890	COG1923	regulation of RNA biosynthetic process
BTXL6_10910	COG1484	DNA-dependent DNA replication
BTXL6_10960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTXL6_10975	COG1525	nuclease
BTXL6_11020	COG1475	DNA binding
BTXL6_11115	COG2801	Transposase and inactivated derivatives
BTXL6_11275	COG2801	Transposase and inactivated derivatives
BTXL6_11340	COG2801	Transposase and inactivated derivatives
BTXL6_11385	COG2226	methyltransferase
BTXL6_11405	COG1215	transferase activity, transferring glycosyl groups
BTXL6_11425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_11430	COG0506	proline dehydrogenase activity
BTXL6_11450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTXL6_11455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTXL6_11460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTXL6_11470	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTXL6_11485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTXL6_11495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTXL6_11505	COG0151	Belongs to the GarS family
BTXL6_11535	COG0210	DNA helicase
BTXL6_11545	COG4851	CamS sex pheromone cAM373 precursor
BTXL6_11565	COG1335	isochorismatase
BTXL6_11575	COG2011	ABC-type metal ion transport system permease component
BTXL6_11580	COG1464	Belongs to the NlpA lipoprotein family
BTXL6_11595	COG0003	Pfam Anion-transporting ATPase
BTXL6_11600	COG1846	Transcriptional regulator
BTXL6_11605	COG4682	membrane
BTXL6_11625	COG1597	lipid kinase activity
BTXL6_11630	COG0546	phosphoglycolate phosphatase activity
BTXL6_11635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTXL6_11645	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_11650	COG2076	Multidrug Resistance protein
BTXL6_11655	COG2309	aminopeptidase activity
BTXL6_11670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTXL6_11675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTXL6_11680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTXL6_11685	COG5002	protein histidine kinase activity
BTXL6_11690	COG4807	Protein conserved in bacteria
BTXL6_11720	COG1473	amidohydrolase
BTXL6_11735	COG0450	alkyl hydroperoxide reductase
BTXL6_11740	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BTXL6_11750	COG0235	Class ii aldolase
BTXL6_11755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_11760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_11765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTXL6_11785	COG0166	Belongs to the GPI family
BTXL6_11830	COG3541	Predicted nucleotidyltransferase
BTXL6_11835	COG2814	Major facilitator Superfamily
BTXL6_11840	COG0723	plastoquinol--plastocyanin reductase activity
BTXL6_11840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTXL6_11850	COG0765	amino acid transport
BTXL6_11855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTXL6_11865	COG0840	transmembrane signaling receptor activity
BTXL6_11890	COG0549	Belongs to the carbamate kinase family
BTXL6_11895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTXL6_11905	COG0277	FAD linked oxidase domain protein
BTXL6_11910	COG0366	Alpha amylase catalytic
BTXL6_11915	COG2190	(PTS) system
BTXL6_11915	COG1263	PTS System
BTXL6_11915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTXL6_11945	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTXL6_11960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTXL6_11970	COG1116	anion transmembrane transporter activity
BTXL6_11980	COG0488	(ABC) transporter
BTXL6_12025	COG2270	Major facilitator Superfamily
BTXL6_12055	COG2310	stress, protein
BTXL6_12060	COG2310	stress, protein
BTXL6_12065	COG2310	stress, protein
BTXL6_12070	COG0861	Integral membrane protein TerC family
BTXL6_12080	COG3853	Toxic anion resistance protein (TelA)
BTXL6_12095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTXL6_12105	COG1295	ribonuclease BN
BTXL6_12110	COG2217	Heavy metal translocating P-type atpase
BTXL6_12115	COG0697	spore germination
BTXL6_12135	COG0586	Pfam SNARE associated Golgi protein
BTXL6_12150	COG3871	stress protein (general stress protein 26)
BTXL6_12155	COG0387	Pfam Sodium calcium exchanger
BTXL6_12165	COG0535	radical SAM domain protein
BTXL6_12185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTXL6_12205	COG3829	transcription factor binding
BTXL6_12215	COG0833	amino acid
BTXL6_12220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTXL6_12250	COG2066	Belongs to the glutaminase family
BTXL6_12255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTXL6_12255	COG1263	PTS System
BTXL6_12260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTXL6_12280	COG0463	Glycosyl transferase, family 2
BTXL6_12290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTXL6_12290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTXL6_12305	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTXL6_12325	COG0402	S-adenosylhomocysteine deaminase activity
BTXL6_12330	COG1090	epimerase
BTXL6_12360	COG1988	membrane-bound metal-dependent
BTXL6_12365	COG1194	a g-specific adenine glycosylase
BTXL6_12390	COG1132	(ABC) transporter
BTXL6_12395	COG4129	membrane
BTXL6_12400	COG0067	glutamate synthase
BTXL6_12400	COG0070	glutamate synthase
BTXL6_12400	COG0069	glutamate synthase activity
BTXL6_12410	COG4555	ABC transporter
BTXL6_12430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTXL6_12435	COG0735	belongs to the Fur family
BTXL6_12550	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTXL6_12555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTXL6_12570	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTXL6_12580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTXL6_12595	COG2766	serine protein kinase
BTXL6_12620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTXL6_12630	COG1585	Membrane protein implicated in regulation of membrane protease activity
BTXL6_12635	COG2268	Band 7 protein
BTXL6_12645	COG3290	protein histidine kinase activity
BTXL6_12650	COG4565	transcriptional regulatory protein
BTXL6_12655	COG2851	Citrate transporter
BTXL6_12680	COG0745	RESPONSE REGULATOR receiver
BTXL6_12685	COG5002	protein histidine kinase activity
BTXL6_12695	COG4990	cell redox homeostasis
BTXL6_12705	COG3290	protein histidine kinase activity
BTXL6_12710	COG4565	transcriptional regulatory protein
BTXL6_12715	COG3493	citrate carrier protein
BTXL6_12720	COG0281	malic enzyme
BTXL6_12730	COG0697	spore germination
BTXL6_12735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_12745	COG5002	protein histidine kinase activity
BTXL6_12750	COG0745	RESPONSE REGULATOR receiver
BTXL6_12760	COG0454	-acetyltransferase
BTXL6_12760	COG0456	acetyltransferase
BTXL6_12765	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTXL6_12770	COG3383	formate dehydrogenase (NAD+) activity
BTXL6_12775	COG2427	Protein of unknown function (DUF1641)
BTXL6_12790	COG0531	amino acid
BTXL6_12795	COG0640	Transcriptional regulator
BTXL6_12800	COG2217	Heavy metal translocating P-type atpase
BTXL6_12805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTXL6_12815	COG3227	Zinc metalloprotease (Elastase)
BTXL6_12835	COG2720	vancomycin resistance protein
BTXL6_12840	COG1316	TRANSCRIPTIONal
BTXL6_12845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTXL6_12850	COG0346	lactoylglutathione lyase activity
BTXL6_12855	COG1253	flavin adenine dinucleotide binding
BTXL6_12860	COG1027	Aspartate ammonia-lyase
BTXL6_12865	COG1620	l-lactate permease
BTXL6_12880	COG3104	oligopeptide transport
BTXL6_12885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTXL6_12890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_12895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_12905	COG2226	methyltransferase
BTXL6_12910	COG0156	8-amino-7-oxononanoate synthase activity
BTXL6_12915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTXL6_12920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BTXL6_12930	COG4548	von Willebrand factor, type A
BTXL6_12935	COG0714	Associated with various cellular activities
BTXL6_12940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTXL6_12960	COG0531	amino acid
BTXL6_12965	COG2188	Transcriptional regulator
BTXL6_12970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTXL6_12970	COG1263	PTS System
BTXL6_12975	COG0366	Alpha amylase catalytic
BTXL6_12990	COG0697	spore germination
BTXL6_12995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTXL6_13000	COG1115	amino acid carrier protein
BTXL6_13005	COG1126	abc transporter atp-binding protein
BTXL6_13010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTXL6_13015	COG0765	amino acid transport
BTXL6_13020	COG0765	amino acid transport
BTXL6_13025	COG0833	amino acid
BTXL6_13040	COG1595	DNA-templated transcription, initiation
BTXL6_13050	COG2378	regulation of single-species biofilm formation
BTXL6_13055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTXL6_13060	COG5002	protein histidine kinase activity
BTXL6_13075	COG0659	secondary active sulfate transmembrane transporter activity
BTXL6_13100	COG0601	transmembrane transport
BTXL6_13105	COG4608	Belongs to the ABC transporter superfamily
BTXL6_13115	COG2271	Major facilitator Superfamily
BTXL6_13120	COG1846	Transcriptional regulator
BTXL6_13125	COG0477	Major facilitator Superfamily
BTXL6_13130	COG1609	Transcriptional regulator
BTXL6_13135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTXL6_13145	COG1129	ABC transporter
BTXL6_13150	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTXL6_13155	COG1879	ABC-type sugar transport system periplasmic component
BTXL6_13160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTXL6_13175	COG1063	alcohol dehydrogenase
BTXL6_13190	COG3568	Endonuclease Exonuclease Phosphatase
BTXL6_13220	COG0840	transmembrane signaling receptor activity
BTXL6_13225	COG3583	domain protein
BTXL6_13225	COG3584	3D domain protein
BTXL6_13230	COG1476	TRANSCRIPTIONal
BTXL6_13245	COG3104	oligopeptide transport
BTXL6_13250	COG1114	Component of the transport system for branched-chain amino acids
BTXL6_13265	COG1113	amino acid transport
BTXL6_13270	COG2252	PERMEase
BTXL6_13285	COG2153	protein acetylation
BTXL6_13295	COG0569	domain protein
BTXL6_13295	COG0475	glutathione-regulated potassium exporter activity
BTXL6_13310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTXL6_13315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BTXL6_13320	COG0833	amino acid
BTXL6_13325	COG4990	cell redox homeostasis
BTXL6_13340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTXL6_13345	COG0697	spore germination
BTXL6_13350	COG0531	amino acid
BTXL6_13365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTXL6_13370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTXL6_13375	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BTXL6_13375	COG1918	ferrous iron import across plasma membrane
BTXL6_13380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTXL6_13385	COG0573	inorganic phosphate transmembrane transporter activity
BTXL6_13390	COG0581	inorganic phosphate transmembrane transporter activity
BTXL6_13400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTXL6_13520	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BTXL6_13545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTXL6_13550	COG1116	anion transmembrane transporter activity
BTXL6_13555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTXL6_13560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTXL6_13565	COG0352	thiamine-phosphate diphosphorylase activity
BTXL6_13570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTXL6_13575	COG2104	thiamine diphosphate biosynthetic process
BTXL6_13585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTXL6_13590	COG0351	phosphomethylpyrimidine kinase
BTXL6_13630	COG2205	protein histidine kinase activity
BTXL6_13635	COG2814	Major facilitator Superfamily
BTXL6_13640	COG1846	Transcriptional regulator
BTXL6_13655	COG2252	PERMEase
BTXL6_13660	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_13680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTXL6_13720	COG0778	Nitroreductase
BTXL6_13725	COG2719	SpoVR family
BTXL6_13735	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTXL6_13740	COG1937	Protein conserved in bacteria
BTXL6_13745	COG0425	Belongs to the sulfur carrier protein TusA family
BTXL6_13745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTXL6_13750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTXL6_13750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_13755	COG0425	Belongs to the sulfur carrier protein TusA family
BTXL6_13760	COG0425	Belongs to the sulfur carrier protein TusA family
BTXL6_13770	COG0425	Belongs to the sulfur carrier protein TusA family
BTXL6_13770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTXL6_13780	COG2210	Belongs to the sulfur carrier protein TusA family
BTXL6_13785	COG0730	response to heat
BTXL6_13795	COG1316	TRANSCRIPTIONal
BTXL6_13800	COG0604	alcohol dehydrogenase
BTXL6_13805	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTXL6_13810	COG2814	Major facilitator Superfamily
BTXL6_13820	COG3711	transcriptional antiterminator
BTXL6_13820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTXL6_13825	COG1447	Phosphotransferase system cellobiose-specific component IIA
BTXL6_13830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BTXL6_13855	COG3584	3D domain protein
BTXL6_13855	COG1388	LysM domain
BTXL6_13860	COG0577	efflux transmembrane transporter activity
BTXL6_13865	COG1136	(ABC) transporter
BTXL6_13870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTXL6_13875	COG5522	Integral membrane protein (intg_mem_TP0381)
BTXL6_13890	COG1114	Component of the transport system for branched-chain amino acids
BTXL6_13895	COG3546	catalase activity
BTXL6_13930	COG0586	Pfam SNARE associated Golgi protein
BTXL6_13965	COG0531	amino acid
BTXL6_13970	COG0475	glutathione-regulated potassium exporter activity
BTXL6_13980	COG1737	Transcriptional regulator
BTXL6_13990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTXL6_13990	COG1263	PTS System
BTXL6_14000	COG2259	Doxx family
BTXL6_14020	COG1522	sequence-specific DNA binding
BTXL6_14030	COG0300	oxidoreductase activity
BTXL6_14040	COG2076	Multidrug Resistance protein
BTXL6_14045	COG2076	Multidrug Resistance protein
BTXL6_14050	COG1309	transcriptional regulator
BTXL6_14055	COG2814	Major facilitator Superfamily
BTXL6_14060	COG1733	regulation of RNA biosynthetic process
BTXL6_14070	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTXL6_14075	COG4533	DNA binding
BTXL6_14080	COG2211	Major facilitator Superfamily
BTXL6_14090	COG0693	protein deglycase activity
BTXL6_14105	COG0531	amino acid
BTXL6_14110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BTXL6_14120	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_14130	COG1132	(ABC) transporter
BTXL6_14135	COG1132	(ABC) transporter
BTXL6_14140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTXL6_14145	COG0765	amino acid transport
BTXL6_14150	COG1126	abc transporter atp-binding protein
BTXL6_14165	COG0189	ligase activity
BTXL6_14195	COG0028	Belongs to the TPP enzyme family
BTXL6_14200	COG3527	Alpha-acetolactate decarboxylase
BTXL6_14215	COG0561	phosphatase activity
BTXL6_14225	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTXL6_14225	COG3409	Peptidoglycan-binding domain 1 protein
BTXL6_14230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTXL6_14250	COG0659	secondary active sulfate transmembrane transporter activity
BTXL6_14265	COG0653	protein targeting
BTXL6_14270	COG2244	polysaccharide biosynthetic process
BTXL6_14280	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTXL6_14285	COG4196	transglutaminase domain protein
BTXL6_14305	COG1024	Enoyl-CoA hydratase
BTXL6_14325	COG1363	Peptidase, m42
BTXL6_14380	COG0305	Participates in initiation and elongation during chromosome replication
BTXL6_14425	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTXL6_14445	COG1396	sequence-specific DNA binding
BTXL6_14450	COG3409	Peptidoglycan-binding domain 1 protein
BTXL6_14465	COG0477	Major facilitator Superfamily
BTXL6_14470	COG3290	protein histidine kinase activity
BTXL6_14475	COG4565	transcriptional regulatory protein
BTXL6_14480	COG3181	Tripartite tricarboxylate transporter family receptor
BTXL6_14485	COG0494	nUDIX hydrolase
BTXL6_14520	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BTXL6_14540	COG0305	Participates in initiation and elongation during chromosome replication
BTXL6_14580	COG0477	Major facilitator Superfamily
BTXL6_14660	COG1183	phosphatidylcholine synthase activity
BTXL6_14680	COG2376	Dihydroxyacetone kinase
BTXL6_14700	COG1959	2 iron, 2 sulfur cluster binding
BTXL6_14725	COG3437	response regulator, receiver
BTXL6_14725	COG2770	Histidine kinase
BTXL6_14775	COG1136	(ABC) transporter
BTXL6_14780	COG0577	efflux transmembrane transporter activity
BTXL6_14785	COG0596	Alpha beta hydrolase
BTXL6_14805	COG3237	CsbD-like
BTXL6_14830	COG1191	sigma factor activity
BTXL6_14840	COG2208	phosphoserine phosphatase activity
BTXL6_14845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTXL6_14850	COG2198	Histidine kinase
BTXL6_14850	COG2205	protein histidine kinase activity
BTXL6_14850	COG0784	Response regulator, receiver
BTXL6_14850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTXL6_14875	COG0393	Putative heavy-metal-binding
BTXL6_14920	COG0420	3'-5' exonuclease activity
BTXL6_14925	COG4717	serine-type aminopeptidase activity
BTXL6_14935	COG1309	transcriptional regulator
BTXL6_14940	COG2814	Major facilitator Superfamily
BTXL6_14945	COG0346	lactoylglutathione lyase activity
BTXL6_14950	COG0346	lactoylglutathione lyase activity
BTXL6_14955	COG0457	Tetratricopeptide repeat
BTXL6_14960	COG2267	carboxylic ester hydrolase activity
BTXL6_14980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BTXL6_14985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTXL6_14995	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTXL6_15010	COG1595	DNA-templated transcription, initiation
BTXL6_15020	COG0772	Belongs to the SEDS family
BTXL6_15030	COG3973	AAA domain
BTXL6_15035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTXL6_15060	COG4980	gas vesicle protein
BTXL6_15065	COG0537	adenosine 5'-monophosphoramidase activity
BTXL6_15070	COG1131	(ABC) transporter
BTXL6_15075	COG4473	ABC transporter
BTXL6_15085	COG1309	transcriptional regulator
BTXL6_15095	COG3402	PFAM membrane-flanked domain
BTXL6_15100	COG3428	Bacterial PH domain
BTXL6_15140	COG3402	PFAM membrane-flanked domain
BTXL6_15145	COG3428	Bacterial PH domain
BTXL6_15150	COG2329	Antibiotic biosynthesis monooxygenase
BTXL6_15155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTXL6_15195	COG1309	transcriptional regulator
BTXL6_15200	COG1511	domain protein
BTXL6_15225	COG2378	regulation of single-species biofilm formation
BTXL6_15230	COG1609	Transcriptional regulator
BTXL6_15240	COG1234	tRNA 3'-trailer cleavage
BTXL6_15245	COG0095	Lipoate-protein ligase
BTXL6_15255	COG0318	PFAM AMP-dependent synthetase and ligase
BTXL6_15280	COG1073	alpha beta
BTXL6_15285	COG1408	metallophosphoesterase
BTXL6_15290	COG1078	dGTPase activity
BTXL6_15300	COG0477	Major facilitator Superfamily
BTXL6_15310	COG1595	DNA-templated transcription, initiation
BTXL6_15315	COG3708	Transcriptional regulator
BTXL6_15315	COG2207	Transcriptional regulator
BTXL6_15330	COG2205	protein histidine kinase activity
BTXL6_15335	COG0745	RESPONSE REGULATOR receiver
BTXL6_15360	COG0501	Belongs to the peptidase M48B family
BTXL6_15365	COG0840	transmembrane signaling receptor activity
BTXL6_15370	COG0697	spore germination
BTXL6_15385	COG0497	DNA recombination
BTXL6_15390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTXL6_15395	COG2224	Isocitrate lyase
BTXL6_15405	COG1278	Cold shock
BTXL6_15420	COG4903	ComK protein
BTXL6_15430	COG0398	Pfam SNARE associated Golgi protein
BTXL6_15490	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTXL6_15515	COG0367	asparagine synthase
BTXL6_15525	COG0753	catalase activity
BTXL6_15530	COG0004	ammonium transporteR
BTXL6_15565	COG2996	Protein conserved in bacteria
BTXL6_15570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTXL6_15580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_15595	COG0561	phosphatase activity
BTXL6_15610	COG0542	response to heat
BTXL6_15620	COG2267	carboxylic ester hydrolase activity
BTXL6_15635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTXL6_15640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTXL6_15645	COG5504	Zn-dependent protease
BTXL6_15655	COG0180	Tryptophanyl-tRNA synthetase
BTXL6_15665	COG4166	transmembrane transport
BTXL6_15670	COG0601	transmembrane transport
BTXL6_15675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTXL6_15680	COG0444	Belongs to the ABC transporter superfamily
BTXL6_15685	COG4608	Belongs to the ABC transporter superfamily
BTXL6_15690	COG0534	Mate efflux family protein
BTXL6_15695	COG4166	transmembrane transport
BTXL6_15710	COG1393	Belongs to the ArsC family
BTXL6_15715	COG0861	Integral membrane protein TerC family
BTXL6_15720	COG4862	establishment of competence for transformation
BTXL6_15725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTXL6_15735	COG1164	Oligoendopeptidase f
BTXL6_15750	COG2346	COG2346, Truncated hemoglobins
BTXL6_15755	COG4116	CYTH
BTXL6_15765	COG2357	RelA SpoT domain protein
BTXL6_15775	COG0564	pseudouridine synthase activity
BTXL6_15790	COG0772	Belongs to the SEDS family
BTXL6_15795	COG1216	Glycosyl transferase, family 2
BTXL6_15815	COG0457	Tetratricopeptide repeat
BTXL6_15815	COG0463	Glycosyl transferase, family 2
BTXL6_15835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BTXL6_15850	COG1091	dTDP-4-dehydrorhamnose reductase activity
BTXL6_15905	COG2153	protein acetylation
BTXL6_15915	COG2382	esterase
BTXL6_15930	COG5492	domain, Protein
BTXL6_15935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTXL6_15950	COG0512	Glutamine amidotransferase of anthranilate synthase
BTXL6_15950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTXL6_15985	COG1620	l-lactate permease
BTXL6_15990	COG5634	Uncharacterized conserved protein (DUF2278)
BTXL6_16050	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTXL6_16060	COG1476	TRANSCRIPTIONal
BTXL6_16130	COG2226	methyltransferase
BTXL6_16140	COG1686	Belongs to the peptidase S11 family
BTXL6_16145	COG0681	Belongs to the peptidase S26 family
BTXL6_16180	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_16190	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTXL6_16195	COG1177	transmembrane transport
BTXL6_16200	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTXL6_16210	COG2409	Drug exporters of the RND superfamily
BTXL6_16220	COG0564	pseudouridine synthase activity
BTXL6_16230	COG2340	Cysteine-rich secretory protein family
BTXL6_16235	COG0247	lactate metabolic process
BTXL6_16240	COG0277	FAD linked oxidase domain protein
BTXL6_16245	COG3835	regulator
BTXL6_16255	COG0745	RESPONSE REGULATOR receiver
BTXL6_16260	COG5002	protein histidine kinase activity
BTXL6_16265	COG2186	Transcriptional regulator
BTXL6_16285	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTXL6_16295	COG2116	formate transmembrane transporter activity
BTXL6_16300	COG0861	Integral membrane protein TerC family
BTXL6_16305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTXL6_16315	COG2030	dehydratase
BTXL6_16335	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_16340	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTXL6_16350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTXL6_16365	COG1840	ABC-type Fe3 transport system, periplasmic component
BTXL6_16370	COG3842	ATPase activity
BTXL6_16395	COG1349	DNA-binding transcription factor activity
BTXL6_16410	COG0235	Class ii aldolase
BTXL6_16420	COG2861	carbohydrate metabolic process
BTXL6_16430	COG3852	Histidine kinase
BTXL6_16435	COG1846	Transcriptional regulator
BTXL6_16445	COG2318	DinB family
BTXL6_16455	COG5002	protein histidine kinase activity
BTXL6_16465	COG0720	synthase
BTXL6_16480	COG4873	Protein conserved in bacteria
BTXL6_16515	COG1780	Probably involved in ribonucleotide reductase function
BTXL6_16530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTXL6_16535	COG1725	Transcriptional regulator
BTXL6_16540	COG1131	(ABC) transporter
BTXL6_16550	COG1131	(ABC) transporter
BTXL6_16555	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTXL6_16560	COG1266	CAAX protease self-immunity
BTXL6_16570	COG1522	sequence-specific DNA binding
BTXL6_16580	COG1335	isochorismatase
BTXL6_16590	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTXL6_16595	COG2070	2-Nitropropane dioxygenase
BTXL6_16600	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTXL6_16610	COG1696	Membrane protein involved in D-alanine export
BTXL6_16635	COG0716	FMN binding
BTXL6_16670	COG0534	Mate efflux family protein
BTXL6_16690	COG1846	Transcriptional regulator
BTXL6_16700	COG1301	dicarboxylic acid transport
BTXL6_16705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTXL6_16710	COG4709	membrane
BTXL6_16715	COG3874	Sporulation protein YtfJ
BTXL6_16745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTXL6_16750	COG0028	Belongs to the TPP enzyme family
BTXL6_16755	COG0440	acetolactate synthase activity
BTXL6_16830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTXL6_16845	COG1183	phosphatidylcholine synthase activity
BTXL6_16850	COG1368	sulfuric ester hydrolase activity
BTXL6_16860	COG0019	diaminopimelate decarboxylase activity
BTXL6_16880	COG0529	Catalyzes the synthesis of activated sulfate
BTXL6_16885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTXL6_16905	COG1648	precorrin-2 dehydrogenase activity
BTXL6_16915	COG0733	neurotransmitter:sodium symporter activity
BTXL6_16935	COG1757	Na H antiporter
BTXL6_16950	COG4758	membrane
BTXL6_16955	COG4585	Histidine kinase
BTXL6_16960	COG2197	response regulator
BTXL6_16970	COG1114	Component of the transport system for branched-chain amino acids
BTXL6_17025	COG0730	response to heat
BTXL6_17030	COG0306	phosphate transporter
BTXL6_17035	COG1392	Phosphate transport regulator
BTXL6_17040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTXL6_17055	COG3852	Histidine kinase
BTXL6_17060	COG1801	Protein of unknown function DUF72
BTXL6_17070	COG0582	viral genome integration into host DNA
BTXL6_17075	COG5002	protein histidine kinase activity
BTXL6_17090	COG0392	lysyltransferase activity
BTXL6_17090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BTXL6_17105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTXL6_17110	COG1686	Belongs to the peptidase S11 family
BTXL6_17115	COG2715	membrane protein required for spore maturation
BTXL6_17120	COG0700	Nucleoside recognition
BTXL6_17125	COG1187	pseudouridine synthase activity
BTXL6_17135	COG1333	cytochrome c biogenesis protein
BTXL6_17140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTXL6_17145	COG0745	RESPONSE REGULATOR receiver
BTXL6_17150	COG5002	protein histidine kinase activity
BTXL6_17155	COG2096	Adenosyltransferase
BTXL6_17160	COG4942	peptidase
BTXL6_17170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BTXL6_17175	COG1141	Ferredoxin
BTXL6_17185	COG0514	ATP-dependent DNA helicase (RecQ)
BTXL6_17190	COG1266	CAAX protease self-immunity
BTXL6_17200	COG1408	metallophosphoesterase
BTXL6_17210	COG4862	establishment of competence for transformation
BTXL6_17215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTXL6_17235	COG0492	ferredoxin-NADP+ reductase activity
BTXL6_17240	COG0252	asparaginase activity
BTXL6_17310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTXL6_17325	COG0142	geranyltranstransferase activity
BTXL6_17335	COG0142	geranyltranstransferase activity
BTXL6_17360	COG0457	Tetratricopeptide repeat
BTXL6_17380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTXL6_17385	COG2010	Cytochrome c
BTXL6_17385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTXL6_17390	COG4347	Protein of unknown function (DUF1405)
BTXL6_17405	COG2738	Putative neutral zinc metallopeptidase
BTXL6_17415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_17420	COG1694	Mazg nucleotide pyrophosphohydrolase
BTXL6_17435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTXL6_17440	COG0438	transferase activity, transferring glycosyl groups
BTXL6_17475	COG1199	ATP-dependent helicase activity
BTXL6_17475	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTXL6_17495	COG3935	DnaD domain protein
BTXL6_17500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTXL6_17510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTXL6_17510	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTXL6_17560	COG0116	Belongs to the methyltransferase superfamily
BTXL6_17570	COG1199	ATP-dependent helicase activity
BTXL6_17575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BTXL6_17585	COG0024	Methionine aminopeptidase
BTXL6_17595	COG2233	PERMEase
BTXL6_17600	COG2311	Membrane
BTXL6_17605	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BTXL6_17615	COG0456	acetyltransferase
BTXL6_17640	COG0754	glutathionylspermidine amidase activity
BTXL6_17655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTXL6_17680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTXL6_17695	COG1215	transferase activity, transferring glycosyl groups
BTXL6_17700	COG0438	transferase activity, transferring glycosyl groups
BTXL6_17715	COG0454	-acetyltransferase
BTXL6_17735	COG0328	RNA-DNA hybrid ribonuclease activity
BTXL6_17770	COG3403	YqcI/YcgG family
BTXL6_17775	COG1280	lysine exporter protein (LysE YggA)
BTXL6_17790	COG3162	membrane
BTXL6_17795	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTXL6_17800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTXL6_17810	COG0475	glutathione-regulated potassium exporter activity
BTXL6_17815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTXL6_17820	COG4978	Transcriptional regulator
BTXL6_17820	COG0789	Transcriptional regulator
BTXL6_17830	COG2323	membrane
BTXL6_17835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTXL6_17860	COG2814	Major facilitator Superfamily
BTXL6_17870	COG2814	Major facilitator Superfamily
BTXL6_17890	COG1923	regulation of RNA biosynthetic process
BTXL6_17900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTXL6_17905	COG1360	Flagellar Motor Protein
BTXL6_17910	COG2201	protein-glutamate methylesterase activity
BTXL6_17915	COG2198	Histidine kinase
BTXL6_17915	COG0643	Histidine kinase
BTXL6_17920	COG1776	CheC inhibitor of MCP methylation
BTXL6_17920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTXL6_17935	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTXL6_17955	COG1256	bacterial-type flagellum assembly
BTXL6_17960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTXL6_17965	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BTXL6_17980	COG1815	bacterial-type flagellum-dependent cell motility
BTXL6_17985	COG1558	bacterial-type flagellum-dependent cell motility
BTXL6_17990	COG1677	Flagellar hook-basal body complex protein FliE
BTXL6_17995	COG1766	The M ring may be actively involved in energy transduction
BTXL6_18000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTXL6_18010	COG1157	protein secretion by the type III secretion system
BTXL6_18045	COG0784	Response regulator, receiver
BTXL6_18045	COG0835	chemotaxis
BTXL6_18060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTXL6_18065	COG0741	lytic transglycosylase activity
BTXL6_18075	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTXL6_18080	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTXL6_18080	COG1776	CheC inhibitor of MCP methylation
BTXL6_18090	COG1338	Plays a role in the flagellum-specific transport system
BTXL6_18095	COG1987	bacterial-type flagellum assembly
BTXL6_18105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTXL6_18110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTXL6_18115	COG1419	protein localization to endoplasmic reticulum
BTXL6_18120	COG4786	Flagellar basal body rod
BTXL6_18125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTXL6_18170	COG2329	Antibiotic biosynthesis monooxygenase
BTXL6_18185	COG3764	Sortase (surface protein transpeptidase)
BTXL6_18190	COG3764	Sortase (surface protein transpeptidase)
BTXL6_18225	COG3842	ATPase activity
BTXL6_18235	COG1177	transmembrane transport
BTXL6_18240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BTXL6_18265	COG1686	Belongs to the peptidase S11 family
BTXL6_18275	COG0406	alpha-ribazole phosphatase activity
BTXL6_18295	COG1846	Transcriptional regulator
BTXL6_18305	COG0367	asparagine synthase
BTXL6_18335	COG1802	Transcriptional regulator
BTXL6_18340	COG0697	spore germination
BTXL6_18345	COG0523	cobalamin synthesis protein
BTXL6_18350	COG0701	Predicted permease
BTXL6_18360	COG1216	Glycosyl transferase, family 2
BTXL6_18360	COG0438	transferase activity, transferring glycosyl groups
BTXL6_18365	COG1757	Na H antiporter
BTXL6_18370	COG0789	Transcriptional regulator
BTXL6_18375	COG4221	oxidoreductase activity
BTXL6_18380	COG0114	fumarate hydratase activity
BTXL6_18395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_18405	COG0534	Mate efflux family protein
BTXL6_18410	COG3340	Belongs to the peptidase S51 family
BTXL6_18450	COG2733	membrane
BTXL6_18485	COG1131	(ABC) transporter
BTXL6_18500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTXL6_18505	COG0528	UMP kinase activity
BTXL6_18515	COG1027	Aspartate ammonia-lyase
BTXL6_18520	COG0281	malic enzyme
BTXL6_18525	COG4191	Histidine kinase
BTXL6_18530	COG0784	Response regulator, receiver
BTXL6_18535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTXL6_18595	COG1051	belongs to the nudix hydrolase family
BTXL6_18640	COG0477	Major facilitator Superfamily
BTXL6_18645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTXL6_18655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTXL6_18660	COG4166	transmembrane transport
BTXL6_18665	COG2223	nitrite transmembrane transporter activity
BTXL6_18670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTXL6_18685	COG2244	polysaccharide biosynthetic process
BTXL6_18690	COG0733	neurotransmitter:sodium symporter activity
BTXL6_18700	COG5566	PFAM Mor transcription activator
BTXL6_18705	COG2323	membrane
BTXL6_18725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTXL6_18730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTXL6_18735	COG0028	Belongs to the TPP enzyme family
BTXL6_18755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTXL6_18780	COG2814	Major facilitator Superfamily
BTXL6_18785	COG3384	dioxygenase
BTXL6_18795	COG3279	Response regulator of the LytR AlgR family
BTXL6_18800	COG0427	acetyl-CoA hydrolase
BTXL6_18820	COG1073	alpha beta
BTXL6_18825	COG4166	transmembrane transport
BTXL6_18840	COG2226	methyltransferase
BTXL6_18850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_18870	COG1914	H( )-stimulated, divalent metal cation uptake system
BTXL6_18885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTXL6_18895	COG0531	amino acid
BTXL6_18930	COG1309	transcriptional regulator
BTXL6_18935	COG2390	Transcriptional regulator
BTXL6_18945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTXL6_18950	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BTXL6_18965	COG4846	Membrane protein involved in cytochrome C biogenesis
BTXL6_18975	COG0006	proline dipeptidase activity
BTXL6_18980	COG2132	Multicopper oxidase
BTXL6_19015	COG1114	Component of the transport system for branched-chain amino acids
BTXL6_19025	COG2372	response to copper ion
BTXL6_19025	COG1276	copper resistance
BTXL6_19030	COG4549	nuclear export factor GLE1
BTXL6_19035	COG0697	spore germination
BTXL6_19040	COG0583	DNA-binding transcription factor activity
BTXL6_19045	COG1959	2 iron, 2 sulfur cluster binding
BTXL6_19050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BTXL6_19055	COG0778	Nitroreductase
BTXL6_19070	COG0628	permease
BTXL6_19080	COG1231	oxidoreductase activity
BTXL6_19085	COG0523	cobalamin synthesis protein
BTXL6_19095	COG0318	PFAM AMP-dependent synthetase and ligase
BTXL6_19100	COG2030	dehydratase
BTXL6_19105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTXL6_19120	COG0411	ABC transporter
BTXL6_19140	COG0583	DNA-binding transcription factor activity
BTXL6_19150	COG1942	4-Oxalocrotonate Tautomerase
BTXL6_19170	COG1271	oxidase subunit
BTXL6_19175	COG1294	oxidase, subunit
BTXL6_19180	COG4988	ABC transporter
BTXL6_19185	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTXL6_19195	COG1216	Glycosyl transferase, family 2
BTXL6_19225	COG1686	Belongs to the peptidase S11 family
BTXL6_19240	COG1388	LysM domain
BTXL6_19240	COG0791	NLP P60 protein
BTXL6_19250	COG1132	(ABC) transporter
BTXL6_19255	COG0745	RESPONSE REGULATOR receiver
BTXL6_19260	COG5002	protein histidine kinase activity
BTXL6_19270	COG0300	oxidoreductase activity
BTXL6_19285	COG0726	polysaccharide deacetylase
BTXL6_19305	COG0460	homoserine dehydrogenase
BTXL6_19330	COG1316	TRANSCRIPTIONal
BTXL6_19340	COG0745	RESPONSE REGULATOR receiver
BTXL6_19345	COG5002	protein histidine kinase activity
BTXL6_19350	COG0726	polysaccharide deacetylase
BTXL6_19360	COG1285	pathogenesis
BTXL6_19365	COG1247	-acetyltransferase
BTXL6_19375	COG4264	IucA IucC family
BTXL6_19380	COG0318	PFAM AMP-dependent synthetase and ligase
BTXL6_19395	COG1082	Xylose isomerase domain protein TIM barrel
BTXL6_19405	COG2814	Major facilitator Superfamily
BTXL6_19410	COG1279	arginine transmembrane transporter activity
BTXL6_19415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_19425	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTXL6_19460	COG0577	efflux transmembrane transporter activity
BTXL6_19465	COG2002	toxin-antitoxin pair type II binding
BTXL6_19470	COG1404	Belongs to the peptidase S8 family
BTXL6_19475	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BTXL6_19480	COG0640	Transcriptional regulator
BTXL6_19485	COG0667	Aldo Keto reductase
BTXL6_19490	COG2814	Major facilitator Superfamily
BTXL6_19530	COG3949	Membrane
BTXL6_19535	COG0783	Belongs to the Dps family
BTXL6_19550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTXL6_19560	COG1231	oxidoreductase activity
BTXL6_19565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_19570	COG4989	oxidoreductase activity
BTXL6_19575	COG0523	cobalamin synthesis protein
BTXL6_19580	COG0456	acetyltransferase
BTXL6_19595	COG3443	Belongs to the bacterial solute-binding protein 9 family
BTXL6_19595	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTXL6_19605	COG0702	epimerase
BTXL6_19615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTXL6_19625	COG4166	transmembrane transport
BTXL6_19640	COG0406	alpha-ribazole phosphatase activity
BTXL6_19650	COG5337	Spore coat protein CotH
BTXL6_19655	COG1051	belongs to the nudix hydrolase family
BTXL6_19660	COG0586	Pfam SNARE associated Golgi protein
BTXL6_19665	COG2244	polysaccharide biosynthetic process
BTXL6_19675	COG0701	Predicted permease
BTXL6_19680	COG3689	TIGRFAM TIGR03943 family protein
BTXL6_19685	COG1607	acyl-coa hydrolase
BTXL6_19690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTXL6_19705	COG0702	epimerase
BTXL6_19710	COG2839	Protein conserved in bacteria
BTXL6_19715	COG1253	flavin adenine dinucleotide binding
BTXL6_19730	COG1114	Component of the transport system for branched-chain amino acids
BTXL6_19735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTXL6_19755	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTXL6_19765	COG1876	peptidase activity
BTXL6_19770	COG0494	nUDIX hydrolase
BTXL6_19800	COG0561	phosphatase activity
BTXL6_19810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTXL6_19830	COG1819	glycosyl
BTXL6_19835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_19840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_19870	COG0456	acetyltransferase
BTXL6_19905	COG3874	Sporulation protein YtfJ
BTXL6_19930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTXL6_19950	COG0346	lactoylglutathione lyase activity
BTXL6_19960	COG0604	alcohol dehydrogenase
BTXL6_19965	COG1595	DNA-templated transcription, initiation
BTXL6_19995	COG0386	Belongs to the glutathione peroxidase family
BTXL6_20000	COG1305	Transglutaminase-like
BTXL6_20005	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BTXL6_20010	COG0714	Associated with various cellular activities
BTXL6_20015	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BTXL6_20020	COG1140	nitrate reductase beta subunit
BTXL6_20025	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BTXL6_20030	COG2181	nitrate reductase activity
BTXL6_20035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTXL6_20040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTXL6_20045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTXL6_20050	COG0303	'Molybdopterin
BTXL6_20055	COG0314	molybdopterin synthase activity
BTXL6_20065	COG2223	nitrite transmembrane transporter activity
BTXL6_20080	COG1648	precorrin-2 dehydrogenase activity
BTXL6_20090	COG1587	Uroporphyrinogen-III synthase
BTXL6_20090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTXL6_20095	COG2146	nitrite reductase [NAD(P)H] activity
BTXL6_20100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTXL6_20105	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BTXL6_20130	COG2359	stage V sporulation protein S
BTXL6_20145	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTXL6_20160	COG2856	Zn peptidase
BTXL6_20170	COG0494	nUDIX hydrolase
BTXL6_20220	COG0305	Participates in initiation and elongation during chromosome replication
BTXL6_20270	COG0582	viral genome integration into host DNA
BTXL6_20385	COG4824	toxin secretion phage lysis holin
BTXL6_20405	COG1418	mRNA catabolic process
BTXL6_20410	COG0488	(ABC) transporter
BTXL6_20425	COG0629	single-stranded DNA binding
BTXL6_20430	COG1413	lyase activity
BTXL6_20445	COG2521	methyltransferase
BTXL6_20445	COG2136	Putative SAM-dependent methyltransferase
BTXL6_20490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTXL6_20495	COG0017	Asparaginyl-tRNA synthetase
BTXL6_20515	COG1674	ftsk spoiiie
BTXL6_20590	COG0733	neurotransmitter:sodium symporter activity
BTXL6_20615	COG2610	gluconate transmembrane transporter activity
BTXL6_20620	COG1454	alcohol dehydrogenase
BTXL6_20625	COG1794	racemase activity, acting on amino acids and derivatives
BTXL6_20635	COG0456	acetyltransferase
BTXL6_20640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTXL6_20650	COG1131	(ABC) transporter
BTXL6_20655	COG4473	ABC transporter
BTXL6_20665	COG0546	phosphoglycolate phosphatase activity
BTXL6_20680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTXL6_20700	COG0768	penicillin binding
BTXL6_20710	COG0204	Acyl-transferase
BTXL6_20715	COG1272	protein, Hemolysin III
BTXL6_20725	COG0805	protein transport
BTXL6_20735	COG1307	EDD domain protein, DegV family
BTXL6_20740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BTXL6_20745	COG1999	signal sequence binding
BTXL6_20750	COG0071	Belongs to the small heat shock protein (HSP20) family
BTXL6_20755	COG0367	asparagine synthase
BTXL6_20775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTXL6_20780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTXL6_20795	COG1335	isochorismatase
BTXL6_20800	COG1051	belongs to the nudix hydrolase family
BTXL6_20805	COG0071	Belongs to the small heat shock protein (HSP20) family
BTXL6_20810	COG0668	transmembrane transport
BTXL6_20815	COG4585	Histidine kinase
BTXL6_20815	COG2203	Gaf domain
BTXL6_20820	COG2197	response regulator
BTXL6_20830	COG1064	alcohol dehydrogenase
BTXL6_20865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTXL6_20905	COG0517	IMP dehydrogenase activity
BTXL6_20905	COG1125	glycine betaine transport
BTXL6_20910	COG1174	glycine betaine transport
BTXL6_20945	COG1253	flavin adenine dinucleotide binding
BTXL6_20950	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_20955	COG5506	Protein of unknown function (DUF1694)
BTXL6_20970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTXL6_20975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BTXL6_20980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTXL6_20985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTXL6_20990	COG0456	acetyltransferase
BTXL6_20995	COG3829	transcription factor binding
BTXL6_21000	COG1509	lysine 2,3-aminomutase activity
BTXL6_21035	COG4991	sh3 domain protein
BTXL6_21035	COG3064	Membrane
BTXL6_21035	COG0515	serine threonine protein kinase
BTXL6_21040	COG4326	sporulation control protein
BTXL6_21045	COG0671	phosphoesterase, PA-phosphatase related
BTXL6_21050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTXL6_21055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTXL6_21095	COG1595	DNA-templated transcription, initiation
BTXL6_21130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTXL6_21165	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_21185	COG4499	WXG100 protein secretion system (Wss), protein YukC
BTXL6_21185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTXL6_21195	COG2814	Major facilitator Superfamily
BTXL6_21200	COG4841	protein insertion into membrane
BTXL6_21205	COG0372	Belongs to the citrate synthase family
BTXL6_21210	COG2079	MmgE PrpD family protein
BTXL6_21215	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTXL6_21220	COG1960	acyl-CoA dehydrogenase activity
BTXL6_21225	COG2084	Dehydrogenase
BTXL6_21230	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_21235	COG1280	lysine exporter protein (LysE YggA)
BTXL6_21240	COG1024	Enoyl-CoA hydratase
BTXL6_21255	COG0420	3'-5' exonuclease activity
BTXL6_21285	COG2223	nitrite transmembrane transporter activity
BTXL6_21290	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_21295	COG1169	isochorismate synthase
BTXL6_21300	COG1021	2,3-dihydroxybenzoate-AMP ligase
BTXL6_21305	COG1535	isochorismatase
BTXL6_21305	COG3433	isochorismatase activity
BTXL6_21310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTXL6_21315	COG3251	PFAM MbtH domain protein
BTXL6_21320	COG2814	Major facilitator Superfamily
BTXL6_21335	COG0776	regulation of translation
BTXL6_21345	COG2318	DinB family
BTXL6_21355	COG1115	amino acid carrier protein
BTXL6_21385	COG2329	Antibiotic biosynthesis monooxygenase
BTXL6_21390	COG1187	pseudouridine synthase activity
BTXL6_21395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTXL6_21405	COG1136	(ABC) transporter
BTXL6_21415	COG0596	Alpha beta hydrolase
BTXL6_21420	COG2814	Major facilitator Superfamily
BTXL6_21435	COG0028	Belongs to the TPP enzyme family
BTXL6_21445	COG2226	methyltransferase
BTXL6_21480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTXL6_21495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_21525	COG1247	-acetyltransferase
BTXL6_21550	COG0596	Alpha beta hydrolase
BTXL6_21565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_21575	COG1278	Cold shock
BTXL6_21590	COG0010	Belongs to the arginase family
BTXL6_21595	COG0561	phosphatase activity
BTXL6_21605	COG0583	DNA-binding transcription factor activity
BTXL6_21610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTXL6_21625	COG0583	DNA-binding transcription factor activity
BTXL6_21630	COG2258	MOSC domain
BTXL6_21645	COG1132	(ABC) transporter
BTXL6_21650	COG1132	(ABC) transporter
BTXL6_21670	COG1396	sequence-specific DNA binding
BTXL6_21700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTXL6_21715	COG1595	DNA-templated transcription, initiation
BTXL6_21740	COG1649	PFAM Uncharacterised BCR, COG1649
BTXL6_21765	COG2971	BadF BadG BcrA BcrD
BTXL6_21775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BTXL6_21795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_21830	COG1309	transcriptional regulator
BTXL6_21845	COG0577	efflux transmembrane transporter activity
BTXL6_21845	COG1136	(ABC) transporter
BTXL6_21850	COG0500	methyltransferase
BTXL6_21850	COG3615	Tellurite resistance protein tehB
BTXL6_21860	COG3961	Belongs to the TPP enzyme family
BTXL6_21865	COG1846	Transcriptional regulator
BTXL6_21895	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTXL6_21905	COG0110	maltose O-acetyltransferase activity
BTXL6_21915	COG0768	penicillin binding
BTXL6_21920	COG1595	DNA-templated transcription, initiation
BTXL6_21940	COG2367	Beta-lactamase
BTXL6_21945	COG0671	phosphoesterase, PA-phosphatase related
BTXL6_21950	COG1609	Transcriptional regulator
BTXL6_21955	COG2814	Major facilitator Superfamily
BTXL6_21960	COG0673	inositol 2-dehydrogenase activity
BTXL6_21990	COG3718	enzyme involved in inositol metabolism
BTXL6_22005	COG3773	Cell wall hydrolase
BTXL6_22010	COG2755	lipolytic protein G-D-S-L family
BTXL6_22010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BTXL6_22020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_22065	COG2226	methyltransferase
BTXL6_22070	COG4585	Histidine kinase
BTXL6_22075	COG2197	response regulator
BTXL6_22080	COG1404	Belongs to the peptidase S8 family
BTXL6_22115	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTXL6_22125	COG1131	(ABC) transporter
BTXL6_22140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_22195	COG0584	glycerophosphoryl diester phosphodiesterase
BTXL6_22205	COG1252	NADH dehydrogenase
BTXL6_22225	COG1131	(ABC) transporter
BTXL6_22235	COG1309	transcriptional regulator
BTXL6_22250	COG1960	acyl-CoA dehydrogenase activity
BTXL6_22255	COG0439	Biotin carboxylase
BTXL6_22260	COG0511	ligase activity, forming carbon-carbon bonds
BTXL6_22265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTXL6_22270	COG1024	Enoyl-CoA hydratase
BTXL6_22275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTXL6_22280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTXL6_22300	COG0572	uridine kinase
BTXL6_22305	COG2318	DinB family
BTXL6_22310	COG1686	Belongs to the peptidase S11 family
BTXL6_22335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTXL6_22355	COG3227	Zinc metalloprotease (Elastase)
BTXL6_22370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTXL6_22385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTXL6_22395	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_22400	COG1733	regulation of RNA biosynthetic process
BTXL6_22405	COG2226	methyltransferase
BTXL6_22435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_22440	COG2368	4-hydroxyphenylacetate
BTXL6_22460	COG2323	membrane
BTXL6_22465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTXL6_22470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTXL6_22485	COG3773	Cell wall hydrolase
BTXL6_22495	COG0745	RESPONSE REGULATOR receiver
BTXL6_22500	COG2205	protein histidine kinase activity
BTXL6_22525	COG1136	(ABC) transporter
BTXL6_22530	COG0577	efflux transmembrane transporter activity
BTXL6_22550	COG0460	homoserine dehydrogenase
BTXL6_22555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_22565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTXL6_22585	COG0582	viral genome integration into host DNA
BTXL6_22625	COG1484	DNA-dependent DNA replication
BTXL6_22665	COG0662	Cupin 2, conserved barrel domain protein
BTXL6_22685	COG0582	viral genome integration into host DNA
BTXL6_22735	COG1802	Transcriptional regulator
BTXL6_22735	COG4626	Terminase
BTXL6_22745	COG0740	serine-type endopeptidase activity
BTXL6_22860	COG2124	cytochrome p450
BTXL6_22895	COG0561	phosphatase activity
BTXL6_22900	COG5002	protein histidine kinase activity
BTXL6_22905	COG1819	glycosyl
BTXL6_22910	COG1794	racemase activity, acting on amino acids and derivatives
BTXL6_22930	COG2205	protein histidine kinase activity
BTXL6_22940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTXL6_22945	COG0604	alcohol dehydrogenase
BTXL6_22950	COG0671	phosphoesterase, PA-phosphatase related
BTXL6_22965	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_23015	COG0693	protein deglycase activity
BTXL6_23025	COG2814	Major facilitator Superfamily
BTXL6_23040	COG0584	glycerophosphoryl diester phosphodiesterase
BTXL6_23055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_23060	COG0697	spore germination
BTXL6_23100	COG2223	nitrite transmembrane transporter activity
BTXL6_23115	COG2816	NAD+ diphosphatase activity
BTXL6_23120	COG0592	DNA-directed DNA polymerase activity
BTXL6_23155	COG3878	Protein conserved in bacteria
BTXL6_23180	COG4667	esterase of the alpha-beta hydrolase superfamily
BTXL6_23220	COG0322	excinuclease ABC activity
BTXL6_23265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTXL6_23310	COG1523	belongs to the glycosyl hydrolase 13 family
BTXL6_23315	COG3227	Zinc metalloprotease (Elastase)
BTXL6_23325	COG0201	protein transport
BTXL6_23335	COG0697	spore germination
BTXL6_23340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_23380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_23395	COG2959	enzyme of heme biosynthesis
BTXL6_23400	COG3409	Peptidoglycan-binding domain 1 protein
BTXL6_23400	COG3773	Cell wall hydrolase
BTXL6_23435	COG1309	transcriptional regulator
BTXL6_23455	COG3284	Transcriptional regulator
BTXL6_23475	COG1349	DNA-binding transcription factor activity
BTXL6_23495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTXL6_23500	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTXL6_23505	COG0022	dehydrogenase e1 component
BTXL6_23510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTXL6_23520	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_23525	COG0456	acetyltransferase
BTXL6_23525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BTXL6_23565	COG4176	ABC-type proline glycine betaine transport system permease component
BTXL6_23570	COG4175	Glycine betaine
BTXL6_23570	COG0517	IMP dehydrogenase activity
BTXL6_23600	COG2153	protein acetylation
BTXL6_23605	COG3397	chitin binding
BTXL6_23610	COG1819	glycosyl
BTXL6_23630	COG2205	protein histidine kinase activity
BTXL6_23635	COG2226	methyltransferase
BTXL6_23640	COG2315	Protein conserved in bacteria
BTXL6_23650	COG2333	competence protein COMEC
BTXL6_23650	COG0658	competence protein
BTXL6_23700	COG3973	AAA domain
BTXL6_23720	COG0514	ATP-dependent DNA helicase (RecQ)
BTXL6_23755	COG4637	Psort location Cytoplasmic, score
BTXL6_23780	COG3397	chitin binding
BTXL6_23795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTXL6_23800	COG1115	amino acid carrier protein
BTXL6_23805	COG1012	belongs to the aldehyde dehydrogenase family
BTXL6_23810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTXL6_23820	COG3938	Belongs to the proline racemase family
BTXL6_23825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTXL6_23865	COG0586	Pfam SNARE associated Golgi protein
BTXL6_23880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BTXL6_23900	COG4166	transmembrane transport
BTXL6_23910	COG4948	Mandelate Racemase Muconate Lactonizing
BTXL6_23955	COG2936	dipeptidyl-peptidase activity
BTXL6_23960	COG5002	protein histidine kinase activity
BTXL6_23960	COG3850	Histidine kinase
BTXL6_23965	COG0745	RESPONSE REGULATOR receiver
BTXL6_24000	COG1164	Oligoendopeptidase f
BTXL6_24005	COG1307	EDD domain protein, DegV family
BTXL6_24055	COG2814	Major facilitator Superfamily
BTXL6_24065	COG1664	Polymer-forming cytoskeletal
BTXL6_24070	COG0789	Transcriptional regulator
BTXL6_24075	COG4533	DNA binding
BTXL6_24080	COG2814	Major facilitator Superfamily
BTXL6_24080	COG0477	Major facilitator Superfamily
BTXL6_24105	COG2261	transglycosylase associated protein
BTXL6_24120	COG2226	methyltransferase
BTXL6_24155	COG0436	Aminotransferase
BTXL6_24160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTXL6_24170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BTXL6_24215	COG0628	permease
BTXL6_24230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTXL6_24235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTXL6_24240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTXL6_24285	COG2746	aminoglycoside 3-N-acetyltransferase activity
BTXL6_24305	COG0697	spore germination
BTXL6_24310	COG2318	DinB family
BTXL6_24340	COG0346	lactoylglutathione lyase activity
BTXL6_24345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_24350	COG0726	polysaccharide deacetylase
BTXL6_24355	COG3037	sugar-specific permease SgaT UlaA
BTXL6_24365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTXL6_24370	COG0861	Integral membrane protein TerC family
BTXL6_24375	COG1368	sulfuric ester hydrolase activity
BTXL6_24380	COG0488	(ABC) transporter
BTXL6_24390	COG1033	growth of symbiont in host cell
BTXL6_24390	COG2409	Drug exporters of the RND superfamily
BTXL6_24395	COG1309	transcriptional regulator
BTXL6_24410	COG0287	Prephenate dehydrogenase
BTXL6_24415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTXL6_24425	COG1605	Chorismate mutase
BTXL6_24425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BTXL6_24455	COG1388	LysM domain
BTXL6_24455	COG3584	3D domain protein
BTXL6_24475	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTXL6_24490	COG2390	Transcriptional regulator
BTXL6_24495	COG1070	Carbohydrate kinase
BTXL6_24530	COG2329	Antibiotic biosynthesis monooxygenase
BTXL6_24550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTXL6_24565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTXL6_24570	COG4187	Peptidase family M20/M25/M40
BTXL6_24575	COG1414	Transcriptional regulator
BTXL6_24580	COG0833	amino acid
BTXL6_24595	COG3239	Fatty acid desaturase
BTXL6_24605	COG1785	Belongs to the alkaline phosphatase family
BTXL6_24615	COG3655	Transcriptional regulator
BTXL6_24630	COG4377	Putative membrane peptidase family (DUF2324)
BTXL6_24640	COG3279	Response regulator of the LytR AlgR family
BTXL6_24655	COG0346	lactoylglutathione lyase activity
BTXL6_24680	COG0714	Associated with various cellular activities
BTXL6_24700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTXL6_24705	COG0753	catalase activity
BTXL6_24720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BTXL6_24745	COG0714	Associated with various cellular activities
BTXL6_24750	COG2824	Alkylphosphonate utilization operon protein PhnA
BTXL6_24755	COG0659	secondary active sulfate transmembrane transporter activity
BTXL6_24775	COG0778	Nitroreductase
BTXL6_24780	COG1846	Transcriptional regulator
BTXL6_24800	COG3831	ATPase activity
BTXL6_24800	COG4884	unkown
BTXL6_24810	COG1136	(ABC) transporter
BTXL6_24835	COG2207	Transcriptional regulator
BTXL6_24840	COG0456	acetyltransferase
BTXL6_24860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTXL6_24900	COG0730	response to heat
BTXL6_24910	COG0833	amino acid
BTXL6_24920	COG4335	DNA alkylation repair
BTXL6_24990	COG1984	allophanate hydrolase subunit 2
BTXL6_24995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTXL6_25000	COG1414	Transcriptional regulator
BTXL6_25010	COG3142	Participates in the control of copper homeostasis
BTXL6_25015	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTXL6_25020	COG1960	acyl-CoA dehydrogenase activity
BTXL6_25050	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BTXL6_25065	COG3848	Pyruvate phosphate dikinase
BTXL6_25065	COG0574	Belongs to the PEP-utilizing enzyme family
BTXL6_25075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_25095	COG1063	alcohol dehydrogenase
BTXL6_25100	COG1027	Aspartate ammonia-lyase
BTXL6_25105	COG0252	asparaginase activity
BTXL6_25110	COG1396	sequence-specific DNA binding
BTXL6_25120	COG5002	protein histidine kinase activity
BTXL6_25145	COG2207	Transcriptional regulator
BTXL6_25160	COG0322	excinuclease ABC activity
BTXL6_25165	COG0531	amino acid
BTXL6_25170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTXL6_25180	COG0531	amino acid
BTXL6_25185	COG0697	spore germination
BTXL6_25190	COG0784	Response regulator, receiver
BTXL6_25195	COG4191	Histidine kinase
BTXL6_25200	COG2066	Belongs to the glutaminase family
BTXL6_25205	COG1115	amino acid carrier protein
BTXL6_25230	COG0737	Belongs to the 5'-nucleotidase family
BTXL6_25235	COG0753	catalase activity
BTXL6_25240	COG2267	carboxylic ester hydrolase activity
BTXL6_25245	COG1335	isochorismatase
BTXL6_25265	COG0583	DNA-binding transcription factor activity
BTXL6_25275	COG0598	Magnesium transport protein CorA
BTXL6_25310	COG0814	amino acid
BTXL6_25320	COG0697	spore germination
BTXL6_25345	COG0415	Belongs to the DNA photolyase family
BTXL6_25360	COG0288	reversible hydration of carbon dioxide
BTXL6_25370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTXL6_25375	COG5609	conserved protein (DUF2294)
BTXL6_25390	COG0697	spore germination
BTXL6_25400	COG1575	Belongs to the MenA family. Type 1 subfamily
BTXL6_25405	COG4641	Protein conserved in bacteria
BTXL6_25410	COG1136	(ABC) transporter
BTXL6_25415	COG0577	efflux transmembrane transporter activity
BTXL6_25445	COG0798	PFAM Bile acid sodium symporter
BTXL6_25450	COG0346	lactoylglutathione lyase activity
BTXL6_25455	COG0640	Transcriptional regulator
BTXL6_25465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTXL6_25475	COG0519	Catalyzes the synthesis of GMP from XMP
BTXL6_25505	COG3320	Male sterility
BTXL6_25505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTXL6_25520	COG2814	Major facilitator Superfamily
BTXL6_25525	COG1309	transcriptional regulator
BTXL6_25555	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_25560	COG1522	sequence-specific DNA binding
BTXL6_25575	COG0346	lactoylglutathione lyase activity
BTXL6_25595	COG2169	Transcriptional regulator
BTXL6_25605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTXL6_25630	COG2814	Major facilitator Superfamily
BTXL6_25675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTXL6_25695	COG1476	TRANSCRIPTIONal
BTXL6_25715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BTXL6_25735	COG0577	efflux transmembrane transporter activity
BTXL6_25755	COG5002	protein histidine kinase activity
BTXL6_25755	COG3850	Histidine kinase
BTXL6_25765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTXL6_25790	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTXL6_25830	COG0814	amino acid
BTXL6_25835	COG1760	l-serine dehydratase
BTXL6_25840	COG1760	l-serine dehydratase
BTXL6_25850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTXL6_25855	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BTXL6_25865	COG1335	isochorismatase
BTXL6_25870	COG1522	sequence-specific DNA binding
BTXL6_25875	COG0531	amino acid
BTXL6_25895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTXL6_25915	COG0662	Cupin 2, conserved barrel domain protein
BTXL6_25920	COG2207	Transcriptional regulator
BTXL6_25920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTXL6_25935	COG3409	Peptidoglycan-binding domain 1 protein
BTXL6_25935	COG5632	N-Acetylmuramoyl-L-alanine amidase
BTXL6_25965	COG1876	peptidase activity
BTXL6_25970	COG2843	Capsule synthesis protein
BTXL6_25980	COG0477	Major facilitator Superfamily
BTXL6_25995	COG1846	Transcriptional regulator
BTXL6_26000	COG2814	Major facilitator Superfamily
BTXL6_26010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BTXL6_26015	COG1131	(ABC) transporter
BTXL6_26035	COG2076	Multidrug Resistance protein
BTXL6_26040	COG1309	transcriptional regulator
BTXL6_26060	COG2031	fatty acid transporter
BTXL6_26100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTXL6_26115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BTXL6_26120	COG1288	antiporter activity
BTXL6_26125	COG2356	endonuclease I
BTXL6_26140	COG3620	sequence-specific DNA binding
BTXL6_26155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTXL6_26175	COG1733	regulation of RNA biosynthetic process
BTXL6_26180	COG0778	Nitroreductase
BTXL6_26200	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_26210	COG1131	(ABC) transporter
BTXL6_26235	COG1011	Hydrolase
BTXL6_26265	COG0346	lactoylglutathione lyase activity
BTXL6_26270	COG1940	carbohydrate kinase activity
BTXL6_26275	COG0110	maltose O-acetyltransferase activity
BTXL6_26285	COG1136	(ABC) transporter
BTXL6_26285	COG0577	efflux transmembrane transporter activity
BTXL6_26290	COG0180	Tryptophanyl-tRNA synthetase
BTXL6_26300	COG0628	permease
BTXL6_26330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTXL6_26340	COG0477	Major facilitator Superfamily
BTXL6_26370	COG1253	flavin adenine dinucleotide binding
BTXL6_26375	COG0789	Transcriptional regulator
BTXL6_26385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTXL6_26410	COG0697	spore germination
BTXL6_26415	COG1357	PFAM Pentapeptide repeats (8 copies)
BTXL6_26420	COG3813	Protein conserved in bacteria
BTXL6_26425	COG2706	6-phosphogluconolactonase activity
BTXL6_26430	COG1070	Carbohydrate kinase
BTXL6_26440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTXL6_26445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BTXL6_26455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTXL6_26460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTXL6_26465	COG0604	alcohol dehydrogenase
BTXL6_26470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTXL6_26490	COG1028	Short-chain dehydrogenase reductase Sdr
BTXL6_26505	COG0840	transmembrane signaling receptor activity
BTXL6_26515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTXL6_26515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTXL6_26520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTXL6_26525	COG1733	regulation of RNA biosynthetic process
BTXL6_26540	COG0656	L-ascorbic acid biosynthetic process
BTXL6_26545	COG2814	Major facilitator Superfamily
BTXL6_26560	COG0346	lactoylglutathione lyase activity
BTXL6_26565	COG0814	amino acid
BTXL6_26590	COG1393	Belongs to the ArsC family
BTXL6_26595	COG1733	regulation of RNA biosynthetic process
BTXL6_26600	COG2188	Transcriptional regulator
BTXL6_26605	COG0673	inositol 2-dehydrogenase activity
BTXL6_26610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTXL6_26615	COG1733	regulation of RNA biosynthetic process
BTXL6_26620	COG1733	regulation of RNA biosynthetic process
BTXL6_26640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTXL6_26660	COG0384	phenazine biosynthesis protein PhzF
BTXL6_26685	COG0318	PFAM AMP-dependent synthetase and ligase
BTXL6_26690	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTXL6_26695	COG1733	regulation of RNA biosynthetic process
BTXL6_26715	COG0726	polysaccharide deacetylase
BTXL6_26725	COG1191	sigma factor activity
BTXL6_26735	COG1280	lysine exporter protein (LysE YggA)
BTXL6_26755	COG3152	Membrane
BTXL6_26785	COG1151	hydroxylamine reductase activity
BTXL6_26800	COG3409	Peptidoglycan-binding domain 1 protein
BTXL6_26800	COG3757	hydrolase, family 25
BTXL6_26835	COG2072	flavoprotein involved in K transport
BTXL6_26875	COG1113	amino acid transport
BTXL6_26880	COG2814	Major facilitator Superfamily
BTXL6_26910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTXL6_26915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTXL6_26930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTXL6_26935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_26940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTXL6_26945	COG3739	integral membrane protein
BTXL6_26965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTXL6_26980	COG0583	DNA-binding transcription factor activity
BTXL6_27000	COG1193	negative regulation of DNA recombination
BTXL6_27015	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BTXL6_27020	COG1164	Oligoendopeptidase f
BTXL6_27045	COG3781	membrane
BTXL6_27060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BTXL6_27090	COG0584	glycerophosphoryl diester phosphodiesterase
BTXL6_27100	COG0640	Transcriptional regulator
BTXL6_27105	COG0604	alcohol dehydrogenase
BTXL6_27115	COG0457	Tetratricopeptide repeat
BTXL6_27125	COG2808	Putative FMN-binding domain
BTXL6_27140	COG0385	Bile acid
BTXL6_27145	COG0277	FAD linked oxidase domain protein
BTXL6_27160	COG0825	malonyl-CoA metabolic process
BTXL6_27185	COG0470	DNA polymerase III
BTXL6_27230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTXL6_27270	COG0457	Tetratricopeptide repeat
BTXL6_27345	COG2002	toxin-antitoxin pair type II binding
BTXL6_27350	COG0653	protein targeting
BTXL6_27355	COG0582	viral genome integration into host DNA
BTXL6_27425	COG1466	dna polymerase III delta subunit
BTXL6_27465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTXL6_27565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTXL6_27595	COG2197	response regulator
BTXL6_27600	COG5002	protein histidine kinase activity
BTXL6_27605	COG1073	alpha beta
BTXL6_27800	COG0305	Participates in initiation and elongation during chromosome replication
BTXL6_27930	COG0592	DNA-directed DNA polymerase activity
BTXL6_27995	COG0791	NLP P60 protein
BTXL6_27995	COG1388	LysM domain
BTXL6_28095	COG5001	Diguanylate cyclase
BTXL6_28095	COG3300	MHYT domain
BTXL6_28120	COG2124	cytochrome p450
BTXL6_28125	COG1846	Transcriptional regulator
BTXL6_28130	COG1846	Transcriptional regulator
BTXL6_28135	COG2814	Major facilitator Superfamily
BTXL6_28165	COG0475	glutathione-regulated potassium exporter activity
BTXL6_28215	COG3335	DDE superfamily endonuclease
BTXL6_28240	COG0697	spore germination
BTXL6_28295	COG0464	growth
BTXL6_28300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTXL6_28410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BTXL6_28455	COG1923	regulation of RNA biosynthetic process
BTXL6_28475	COG1484	DNA-dependent DNA replication
BTXL6_28525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTXL6_28540	COG1525	nuclease
BTXL6_28585	COG1475	DNA binding
BTXL6_28680	COG2801	Transposase and inactivated derivatives
BTXL6_28840	COG2801	Transposase and inactivated derivatives
BTXL6_28905	COG2801	Transposase and inactivated derivatives