locus-tag	class	description
Bt4C1_00020	COG0517	IMP dehydrogenase activity
Bt4C1_00020	COG0516	GMP reductase activity
Bt4C1_00025	COG1686	Belongs to the peptidase S11 family
Bt4C1_00055	COG1428	Deoxynucleoside kinase
Bt4C1_00060	COG1428	Deoxynucleoside kinase
Bt4C1_00065	COG1335	isochorismatase
Bt4C1_00070	COG0590	tRNA wobble adenosine to inosine editing
Bt4C1_00080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Bt4C1_00135	COG1982	Orn Lys Arg decarboxylase major
Bt4C1_00145	COG0470	DNA polymerase III
Bt4C1_00150	COG1774	PSP1 C-terminal conserved region
Bt4C1_00160	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Bt4C1_00170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Bt4C1_00175	COG2002	toxin-antitoxin pair type II binding
Bt4C1_00185	COG0084	hydrolase, TatD family'
Bt4C1_00205	COG4466	Protein conserved in bacteria
Bt4C1_00220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bt4C1_00225	COG0251	oxidation-reduction process
Bt4C1_00240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Bt4C1_00255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Bt4C1_00260	COG2002	toxin-antitoxin pair type II binding
Bt4C1_00265	COG2244	polysaccharide biosynthetic process
Bt4C1_00270	COG3956	TIGRFAM MazG family protein
Bt4C1_00275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Bt4C1_00295	COG1098	S1 RNA binding domain
Bt4C1_00310	COG2208	phosphoserine phosphatase activity
Bt4C1_00325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Bt4C1_00340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_00345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Bt4C1_00350	COG0512	Glutamine amidotransferase of anthranilate synthase
Bt4C1_00355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_00360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Bt4C1_00365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Bt4C1_00370	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Bt4C1_00375	COG1396	sequence-specific DNA binding
Bt4C1_00380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bt4C1_00410	COG3880	PFAM UvrB UvrC protein
Bt4C1_00420	COG0542	response to heat
Bt4C1_00425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Bt4C1_00435	COG4956	integral membrane protein (PIN domain superfamily)
Bt4C1_00455	COG1045	serine acetyltransferase
Bt4C1_00470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bt4C1_00475	COG3688	RNA-binding protein containing a PIN domain
Bt4C1_00485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bt4C1_00490	COG0250	Participates in transcription elongation, termination and antitermination
Bt4C1_00515	COG2813	Specifically methylates the guanine in position
Bt4C1_00530	COG1358	cellular component organization or biogenesis
Bt4C1_00635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Bt4C1_00660	COG0201	protein transport
Bt4C1_00670	COG0024	Methionine aminopeptidase
Bt4C1_00680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Bt4C1_00715	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Bt4C1_00740	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_00745	COG0489	protein tyrosine kinase activity
Bt4C1_00755	COG2194	sulfuric ester hydrolase activity
Bt4C1_00760	COG0726	polysaccharide deacetylase
Bt4C1_00840	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Bt4C1_00845	COG4856	YbbR-like protein
Bt4C1_00880	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_00885	COG2011	ABC-type metal ion transport system permease component
Bt4C1_00890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Bt4C1_00895	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_00900	COG0604	alcohol dehydrogenase
Bt4C1_00910	COG0277	FAD linked oxidase domain protein
Bt4C1_00915	COG2271	Major facilitator Superfamily
Bt4C1_00925	COG2814	Major facilitator Superfamily
Bt4C1_00945	COG0601	transmembrane transport
Bt4C1_00950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_00955	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_00960	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_00965	COG4166	transmembrane transport
Bt4C1_00980	COG4166	transmembrane transport
Bt4C1_00985	COG4166	transmembrane transport
Bt4C1_00990	COG0656	L-ascorbic acid biosynthetic process
Bt4C1_01005	COG4149	molybdate abc transporter
Bt4C1_01010	COG0725	ABC transporter, periplasmic molybdate-binding protein
Bt4C1_01015	COG1910	domain protein
Bt4C1_01025	COG0697	spore germination
Bt4C1_01035	COG0204	Acyl-transferase
Bt4C1_01040	COG1609	Transcriptional regulator
Bt4C1_01050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_01070	COG5298	Protein conserved in bacteria
Bt4C1_01090	COG0488	(ABC) transporter
Bt4C1_01100	COG0747	negative chemotaxis
Bt4C1_01105	COG0601	transmembrane transport
Bt4C1_01115	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_01120	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_01125	COG0561	phosphatase activity
Bt4C1_01160	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Bt4C1_01165	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bt4C1_01175	COG0531	amino acid
Bt4C1_01180	COG2814	Major facilitator Superfamily
Bt4C1_01190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bt4C1_01200	COG4294	response to UV
Bt4C1_01205	COG0705	Rhomboid family
Bt4C1_01215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Bt4C1_01220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Bt4C1_01225	COG0864	Transcriptional regulator
Bt4C1_01230	COG2337	Toxic component of a toxin-antitoxin (TA) module
Bt4C1_01235	COG2183	response to ionizing radiation
Bt4C1_01330	COG0802	atpase or kinase
Bt4C1_01335	COG1214	PFAM Peptidase M22, glycoprotease
Bt4C1_01340	COG0456	acetyltransferase
Bt4C1_01350	COG0488	(ABC) transporter
Bt4C1_01365	COG1266	CAAX protease self-immunity
Bt4C1_01385	COG2252	PERMEase
Bt4C1_01395	COG5002	protein histidine kinase activity
Bt4C1_01420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Bt4C1_01460	COG2205	protein histidine kinase activity
Bt4C1_01465	COG0745	RESPONSE REGULATOR receiver
Bt4C1_01485	COG0697	spore germination
Bt4C1_01510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Bt4C1_01515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Bt4C1_01520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Bt4C1_01530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bt4C1_01545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Bt4C1_01555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Bt4C1_01565	COG0151	Belongs to the GarS family
Bt4C1_01590	COG0210	DNA helicase
Bt4C1_01600	COG4851	CamS sex pheromone cAM373 precursor
Bt4C1_01615	COG1335	isochorismatase
Bt4C1_01625	COG2011	ABC-type metal ion transport system permease component
Bt4C1_01630	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_01640	COG0003	Pfam Anion-transporting ATPase
Bt4C1_01645	COG1846	Transcriptional regulator
Bt4C1_01650	COG4682	membrane
Bt4C1_01670	COG1597	lipid kinase activity
Bt4C1_01680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_01690	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_01695	COG2076	Multidrug Resistance protein
Bt4C1_01705	COG2309	aminopeptidase activity
Bt4C1_01720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_01730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bt4C1_01735	COG4807	Protein conserved in bacteria
Bt4C1_01765	COG1473	amidohydrolase
Bt4C1_01780	COG0450	alkyl hydroperoxide reductase
Bt4C1_01785	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Bt4C1_01795	COG0235	Class ii aldolase
Bt4C1_01800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_01805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_01810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_01825	COG0166	Belongs to the GPI family
Bt4C1_01850	COG5002	protein histidine kinase activity
Bt4C1_01870	COG3541	Predicted nucleotidyltransferase
Bt4C1_01875	COG2814	Major facilitator Superfamily
Bt4C1_01880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_01880	COG0723	plastoquinol--plastocyanin reductase activity
Bt4C1_01890	COG0765	amino acid transport
Bt4C1_01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_01900	COG1126	abc transporter atp-binding protein
Bt4C1_01905	COG0840	transmembrane signaling receptor activity
Bt4C1_01930	COG0549	Belongs to the carbamate kinase family
Bt4C1_01935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_01945	COG0277	FAD linked oxidase domain protein
Bt4C1_01950	COG0366	Alpha amylase catalytic
Bt4C1_01955	COG2190	(PTS) system
Bt4C1_01955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_01955	COG1263	PTS System
Bt4C1_01985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Bt4C1_02005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_02010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_02015	COG1116	anion transmembrane transporter activity
Bt4C1_02060	COG2270	Major facilitator Superfamily
Bt4C1_02090	COG2310	stress, protein
Bt4C1_02095	COG2310	stress, protein
Bt4C1_02100	COG2310	stress, protein
Bt4C1_02105	COG0861	Integral membrane protein TerC family
Bt4C1_02115	COG3853	Toxic anion resistance protein (TelA)
Bt4C1_02130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Bt4C1_02140	COG1295	ribonuclease BN
Bt4C1_02145	COG2217	Heavy metal translocating P-type atpase
Bt4C1_02150	COG0697	spore germination
Bt4C1_02170	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_02185	COG3871	stress protein (general stress protein 26)
Bt4C1_02190	COG0387	Pfam Sodium calcium exchanger
Bt4C1_02200	COG0535	radical SAM domain protein
Bt4C1_02220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Bt4C1_02225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bt4C1_02245	COG3829	transcription factor binding
Bt4C1_02255	COG0833	amino acid
Bt4C1_02260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bt4C1_02280	COG2066	Belongs to the glutaminase family
Bt4C1_02285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_02285	COG1263	PTS System
Bt4C1_02290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bt4C1_02305	COG0463	Glycosyl transferase, family 2
Bt4C1_02315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bt4C1_02315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Bt4C1_02320	COG0463	Glycosyl transferase, family 2
Bt4C1_02330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Bt4C1_02350	COG1228	amidohydrolase
Bt4C1_02355	COG1090	epimerase
Bt4C1_02385	COG1988	membrane-bound metal-dependent
Bt4C1_02390	COG1194	a g-specific adenine glycosylase
Bt4C1_02415	COG1132	(ABC) transporter
Bt4C1_02420	COG4129	membrane
Bt4C1_02425	COG0070	glutamate synthase
Bt4C1_02425	COG0069	glutamate synthase activity
Bt4C1_02425	COG0067	glutamate synthase
Bt4C1_02435	COG4555	ABC transporter
Bt4C1_02455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Bt4C1_02460	COG0735	belongs to the Fur family
Bt4C1_02565	COG4974	Belongs to the 'phage' integrase family
Bt4C1_02655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Bt4C1_02680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Bt4C1_02690	COG2766	serine protein kinase
Bt4C1_02705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bt4C1_02715	COG1585	Membrane protein implicated in regulation of membrane protease activity
Bt4C1_02720	COG2268	Band 7 protein
Bt4C1_02730	COG3290	protein histidine kinase activity
Bt4C1_02735	COG4565	transcriptional regulatory protein
Bt4C1_02740	COG2851	Citrate transporter
Bt4C1_02765	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Bt4C1_02770	COG3842	ATPase activity
Bt4C1_02775	COG1175	transmembrane transport
Bt4C1_02780	COG0395	ABC-type sugar transport system, permease component
Bt4C1_02790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Bt4C1_02795	COG0745	RESPONSE REGULATOR receiver
Bt4C1_02800	COG5002	protein histidine kinase activity
Bt4C1_02810	COG4990	cell redox homeostasis
Bt4C1_02820	COG3290	protein histidine kinase activity
Bt4C1_02825	COG4565	transcriptional regulatory protein
Bt4C1_02830	COG3493	citrate carrier protein
Bt4C1_02835	COG0281	malic enzyme
Bt4C1_02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_02860	COG5002	protein histidine kinase activity
Bt4C1_02885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Bt4C1_02890	COG3383	formate dehydrogenase (NAD+) activity
Bt4C1_02895	COG2427	Protein of unknown function (DUF1641)
Bt4C1_02910	COG0531	amino acid
Bt4C1_02915	COG0640	Transcriptional regulator
Bt4C1_02920	COG2217	Heavy metal translocating P-type atpase
Bt4C1_02925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Bt4C1_02935	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_02955	COG2720	vancomycin resistance protein
Bt4C1_02960	COG1316	TRANSCRIPTIONal
Bt4C1_02965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_02970	COG0346	lactoylglutathione lyase activity
Bt4C1_02975	COG1253	flavin adenine dinucleotide binding
Bt4C1_02980	COG1027	Aspartate ammonia-lyase
Bt4C1_02985	COG1620	l-lactate permease
Bt4C1_03000	COG3104	oligopeptide transport
Bt4C1_03005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_03010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_03015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_03030	COG0156	8-amino-7-oxononanoate synthase activity
Bt4C1_03035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bt4C1_03045	COG4548	von Willebrand factor, type A
Bt4C1_03050	COG0714	Associated with various cellular activities
Bt4C1_03070	COG0531	amino acid
Bt4C1_03075	COG2188	Transcriptional regulator
Bt4C1_03080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_03080	COG1263	PTS System
Bt4C1_03085	COG0366	Alpha amylase catalytic
Bt4C1_03100	COG0697	spore germination
Bt4C1_03110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Bt4C1_03115	COG1115	amino acid carrier protein
Bt4C1_03125	COG1126	abc transporter atp-binding protein
Bt4C1_03130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_03135	COG0765	amino acid transport
Bt4C1_03140	COG0765	amino acid transport
Bt4C1_03145	COG0833	amino acid
Bt4C1_03160	COG1595	DNA-templated transcription, initiation
Bt4C1_03170	COG2378	regulation of single-species biofilm formation
Bt4C1_03175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Bt4C1_03180	COG5002	protein histidine kinase activity
Bt4C1_03205	COG0659	secondary active sulfate transmembrane transporter activity
Bt4C1_03220	COG2271	Major facilitator Superfamily
Bt4C1_03225	COG1846	Transcriptional regulator
Bt4C1_03230	COG0477	Major facilitator Superfamily
Bt4C1_03235	COG1609	Transcriptional regulator
Bt4C1_03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bt4C1_03255	COG4974	Belongs to the 'phage' integrase family
Bt4C1_03350	COG3331	DNA recombination
Bt4C1_03490	COG4824	toxin secretion phage lysis holin
Bt4C1_03525	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bt4C1_03530	COG1879	ABC-type sugar transport system periplasmic component
Bt4C1_03535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Bt4C1_03560	COG1063	alcohol dehydrogenase
Bt4C1_03610	COG0840	transmembrane signaling receptor activity
Bt4C1_03615	COG3584	3D domain protein
Bt4C1_03615	COG3583	domain protein
Bt4C1_03620	COG1476	TRANSCRIPTIONal
Bt4C1_03640	COG3104	oligopeptide transport
Bt4C1_03645	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_03660	COG1113	amino acid transport
Bt4C1_03665	COG2252	PERMEase
Bt4C1_03680	COG2153	protein acetylation
Bt4C1_03690	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_03690	COG0569	domain protein
Bt4C1_03705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Bt4C1_03710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Bt4C1_03715	COG0833	amino acid
Bt4C1_03720	COG4990	cell redox homeostasis
Bt4C1_03735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_03740	COG0697	spore germination
Bt4C1_03745	COG0531	amino acid
Bt4C1_03755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bt4C1_03760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bt4C1_03765	COG1918	ferrous iron import across plasma membrane
Bt4C1_03765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bt4C1_03770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Bt4C1_03775	COG0573	inorganic phosphate transmembrane transporter activity
Bt4C1_03780	COG0581	inorganic phosphate transmembrane transporter activity
Bt4C1_03790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Bt4C1_03905	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Bt4C1_03925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Bt4C1_03930	COG1116	anion transmembrane transporter activity
Bt4C1_03935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_03940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_03945	COG0352	thiamine-phosphate diphosphorylase activity
Bt4C1_03950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_03955	COG2104	thiamine diphosphate biosynthetic process
Bt4C1_03965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_03970	COG0351	phosphomethylpyrimidine kinase
Bt4C1_04010	COG2205	protein histidine kinase activity
Bt4C1_04015	COG2814	Major facilitator Superfamily
Bt4C1_04020	COG1846	Transcriptional regulator
Bt4C1_04035	COG2252	PERMEase
Bt4C1_04040	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_04100	COG0778	Nitroreductase
Bt4C1_04105	COG2719	SpoVR family
Bt4C1_04115	COG1937	Protein conserved in bacteria
Bt4C1_04120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_04120	COG0425	Belongs to the sulfur carrier protein TusA family
Bt4C1_04125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_04125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_04130	COG0425	Belongs to the sulfur carrier protein TusA family
Bt4C1_04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_04135	COG0425	Belongs to the sulfur carrier protein TusA family
Bt4C1_04145	COG2210	Belongs to the sulfur carrier protein TusA family
Bt4C1_04150	COG0730	response to heat
Bt4C1_04160	COG1316	TRANSCRIPTIONal
Bt4C1_04165	COG0604	alcohol dehydrogenase
Bt4C1_04170	COG1283	sodium-dependent phosphate transmembrane transporter activity
Bt4C1_04185	COG3711	transcriptional antiterminator
Bt4C1_04185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bt4C1_04190	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bt4C1_04195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bt4C1_04220	COG1388	LysM domain
Bt4C1_04220	COG3584	3D domain protein
Bt4C1_04225	COG0577	efflux transmembrane transporter activity
Bt4C1_04230	COG1136	(ABC) transporter
Bt4C1_04240	COG5522	Integral membrane protein (intg_mem_TP0381)
Bt4C1_04255	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_04260	COG3546	catalase activity
Bt4C1_04295	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_04325	COG0531	amino acid
Bt4C1_04330	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_04340	COG1737	Transcriptional regulator
Bt4C1_04350	COG1263	PTS System
Bt4C1_04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_04360	COG2259	Doxx family
Bt4C1_04380	COG1522	sequence-specific DNA binding
Bt4C1_04390	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_04395	COG0789	Transcriptional regulator
Bt4C1_04400	COG2076	Multidrug Resistance protein
Bt4C1_04410	COG1309	transcriptional regulator
Bt4C1_04415	COG2814	Major facilitator Superfamily
Bt4C1_04425	COG2801	Transposase and inactivated derivatives
Bt4C1_04430	COG1733	regulation of RNA biosynthetic process
Bt4C1_04450	COG0693	protein deglycase activity
Bt4C1_04455	COG0753	catalase activity
Bt4C1_04455	COG0693	protein deglycase activity
Bt4C1_04465	COG0531	amino acid
Bt4C1_04470	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_04475	COG1132	(ABC) transporter
Bt4C1_04480	COG1132	(ABC) transporter
Bt4C1_04485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_04490	COG0765	amino acid transport
Bt4C1_04495	COG1126	abc transporter atp-binding protein
Bt4C1_04510	COG0189	ligase activity
Bt4C1_04540	COG0028	Belongs to the TPP enzyme family
Bt4C1_04545	COG3527	Alpha-acetolactate decarboxylase
Bt4C1_04560	COG0561	phosphatase activity
Bt4C1_04565	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_04565	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_04570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bt4C1_04585	COG0659	secondary active sulfate transmembrane transporter activity
Bt4C1_04590	COG2244	polysaccharide biosynthetic process
Bt4C1_04610	COG1024	Enoyl-CoA hydratase
Bt4C1_04630	COG1363	Peptidase, m42
Bt4C1_04670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_04675	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_04680	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_04690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_04710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Bt4C1_04725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_04730	COG2814	Major facilitator Superfamily
Bt4C1_04760	COG2801	Transposase and inactivated derivatives
Bt4C1_04835	COG0477	Major facilitator Superfamily
Bt4C1_04840	COG3290	protein histidine kinase activity
Bt4C1_04845	COG4565	transcriptional regulatory protein
Bt4C1_04850	COG3181	Tripartite tricarboxylate transporter family receptor
Bt4C1_04885	COG1401	restriction endodeoxyribonuclease activity
Bt4C1_04905	COG0305	Participates in initiation and elongation during chromosome replication
Bt4C1_04935	COG0477	Major facilitator Superfamily
Bt4C1_04950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_04975	COG1073	alpha beta
Bt4C1_05025	COG1183	phosphatidylcholine synthase activity
Bt4C1_05035	COG2814	Major facilitator Superfamily
Bt4C1_05040	COG0640	Transcriptional regulator
Bt4C1_05050	COG2376	Dihydroxyacetone kinase
Bt4C1_05070	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_05095	COG2373	Large extracellular alpha-helical protein
Bt4C1_05135	COG3237	CsbD-like
Bt4C1_05160	COG1191	sigma factor activity
Bt4C1_05170	COG2208	phosphoserine phosphatase activity
Bt4C1_05175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bt4C1_05215	COG3344	reverse transcriptase
Bt4C1_05225	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Bt4C1_05245	COG0420	3'-5' exonuclease activity
Bt4C1_05250	COG4717	serine-type aminopeptidase activity
Bt4C1_05260	COG4974	Belongs to the 'phage' integrase family
Bt4C1_05290	COG3646	Phage regulatory protein
Bt4C1_05360	COG3331	DNA recombination
Bt4C1_05550	COG1280	lysine exporter protein (LysE YggA)
Bt4C1_05555	COG0346	lactoylglutathione lyase activity
Bt4C1_05560	COG0346	lactoylglutathione lyase activity
Bt4C1_05565	COG0457	Tetratricopeptide repeat
Bt4C1_05575	COG2267	carboxylic ester hydrolase activity
Bt4C1_05590	COG2140	Oxalate decarboxylase
Bt4C1_05595	COG3620	sequence-specific DNA binding
Bt4C1_05600	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Bt4C1_05605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Bt4C1_05615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Bt4C1_05620	COG1695	Transcriptional regulator
Bt4C1_05640	COG0772	Belongs to the SEDS family
Bt4C1_05645	COG3973	AAA domain
Bt4C1_05675	COG4980	gas vesicle protein
Bt4C1_05680	COG0537	adenosine 5'-monophosphoramidase activity
Bt4C1_05685	COG1131	(ABC) transporter
Bt4C1_05690	COG4473	ABC transporter
Bt4C1_05700	COG1309	transcriptional regulator
Bt4C1_05710	COG3402	PFAM membrane-flanked domain
Bt4C1_05715	COG3428	Bacterial PH domain
Bt4C1_05750	COG0697	spore germination
Bt4C1_05755	COG3402	PFAM membrane-flanked domain
Bt4C1_05760	COG3428	Bacterial PH domain
Bt4C1_05765	COG2329	Antibiotic biosynthesis monooxygenase
Bt4C1_05770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_05810	COG1309	transcriptional regulator
Bt4C1_05815	COG1511	domain protein
Bt4C1_05840	COG1609	Transcriptional regulator
Bt4C1_05850	COG1234	tRNA 3'-trailer cleavage
Bt4C1_05855	COG0095	Lipoate-protein ligase
Bt4C1_05865	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_05890	COG1309	transcriptional regulator
Bt4C1_05895	COG1073	alpha beta
Bt4C1_05900	COG1408	metallophosphoesterase
Bt4C1_05905	COG1078	dGTPase activity
Bt4C1_05915	COG1595	DNA-templated transcription, initiation
Bt4C1_05920	COG3708	Transcriptional regulator
Bt4C1_05920	COG2207	Transcriptional regulator
Bt4C1_05930	COG2205	protein histidine kinase activity
Bt4C1_05955	COG0501	Belongs to the peptidase M48B family
Bt4C1_05960	COG0840	transmembrane signaling receptor activity
Bt4C1_05970	COG3693	PFAM glycoside hydrolase, family 10
Bt4C1_05980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Bt4C1_05985	COG2224	Isocitrate lyase
Bt4C1_06000	COG1278	Cold shock
Bt4C1_06015	COG4903	ComK protein
Bt4C1_06020	COG0398	Pfam SNARE associated Golgi protein
Bt4C1_06080	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bt4C1_06105	COG0367	asparagine synthase
Bt4C1_06115	COG0753	catalase activity
Bt4C1_06120	COG0004	ammonium transporteR
Bt4C1_06140	COG2996	Protein conserved in bacteria
Bt4C1_06150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_06165	COG0561	phosphatase activity
Bt4C1_06185	COG2267	carboxylic ester hydrolase activity
Bt4C1_06200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bt4C1_06205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Bt4C1_06210	COG5504	Zn-dependent protease
Bt4C1_06225	COG0180	Tryptophanyl-tRNA synthetase
Bt4C1_06235	COG4166	transmembrane transport
Bt4C1_06240	COG0601	transmembrane transport
Bt4C1_06245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bt4C1_06250	COG0444	Belongs to the ABC transporter superfamily
Bt4C1_06255	COG4608	Belongs to the ABC transporter superfamily
Bt4C1_06260	COG0534	Mate efflux family protein
Bt4C1_06265	COG4166	transmembrane transport
Bt4C1_06275	COG1393	Belongs to the ArsC family
Bt4C1_06280	COG0861	Integral membrane protein TerC family
Bt4C1_06290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_06300	COG1164	Oligoendopeptidase f
Bt4C1_06310	COG2346	COG2346, Truncated hemoglobins
Bt4C1_06315	COG4116	CYTH
Bt4C1_06325	COG2357	RelA SpoT domain protein
Bt4C1_06335	COG0564	pseudouridine synthase activity
Bt4C1_06350	COG0772	Belongs to the SEDS family
Bt4C1_06355	COG1216	Glycosyl transferase, family 2
Bt4C1_06375	COG0463	Glycosyl transferase, family 2
Bt4C1_06375	COG0457	Tetratricopeptide repeat
Bt4C1_06395	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Bt4C1_06410	COG1091	dTDP-4-dehydrorhamnose reductase activity
Bt4C1_06455	COG2153	protein acetylation
Bt4C1_06465	COG2382	esterase
Bt4C1_06480	COG5492	domain, Protein
Bt4C1_06485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_06495	COG0512	Glutamine amidotransferase of anthranilate synthase
Bt4C1_06495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Bt4C1_06530	COG1620	l-lactate permease
Bt4C1_06540	COG5634	Uncharacterized conserved protein (DUF2278)
Bt4C1_06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bt4C1_06605	COG1476	TRANSCRIPTIONal
Bt4C1_06630	COG4152	abc transporter atp-binding protein
Bt4C1_06635	COG1668	transmembrane transport
Bt4C1_06665	COG1686	Belongs to the peptidase S11 family
Bt4C1_06670	COG0681	Belongs to the peptidase S26 family
Bt4C1_06705	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_06715	COG1176	ABC-type spermidine putrescine transport system, permease component I
Bt4C1_06720	COG1177	transmembrane transport
Bt4C1_06725	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Bt4C1_06730	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_06735	COG2409	Drug exporters of the RND superfamily
Bt4C1_06745	COG0564	pseudouridine synthase activity
Bt4C1_06755	COG2340	Cysteine-rich secretory protein family
Bt4C1_06760	COG0247	lactate metabolic process
Bt4C1_06765	COG0277	FAD linked oxidase domain protein
Bt4C1_06770	COG3835	regulator
Bt4C1_06780	COG0745	RESPONSE REGULATOR receiver
Bt4C1_06785	COG5002	protein histidine kinase activity
Bt4C1_06790	COG2186	Transcriptional regulator
Bt4C1_06810	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Bt4C1_06820	COG2116	formate transmembrane transporter activity
Bt4C1_06825	COG0861	Integral membrane protein TerC family
Bt4C1_06830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bt4C1_06840	COG2030	dehydratase
Bt4C1_06860	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_06865	COG3243	poly(R)-hydroxyalkanoic acid synthase
Bt4C1_06875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bt4C1_06890	COG1840	ABC-type Fe3 transport system, periplasmic component
Bt4C1_06895	COG3842	ATPase activity
Bt4C1_06920	COG1349	DNA-binding transcription factor activity
Bt4C1_06935	COG0235	Class ii aldolase
Bt4C1_06945	COG2861	carbohydrate metabolic process
Bt4C1_06955	COG3852	Histidine kinase
Bt4C1_06960	COG1846	Transcriptional regulator
Bt4C1_06970	COG2318	DinB family
Bt4C1_06980	COG5002	protein histidine kinase activity
Bt4C1_06990	COG0720	synthase
Bt4C1_07005	COG4873	Protein conserved in bacteria
Bt4C1_07035	COG1780	Probably involved in ribonucleotide reductase function
Bt4C1_07040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bt4C1_07045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bt4C1_07050	COG1725	Transcriptional regulator
Bt4C1_07055	COG1131	(ABC) transporter
Bt4C1_07065	COG1131	(ABC) transporter
Bt4C1_07080	COG2801	Transposase and inactivated derivatives
Bt4C1_07095	COG1522	sequence-specific DNA binding
Bt4C1_07105	COG1335	isochorismatase
Bt4C1_07115	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bt4C1_07120	COG2070	2-Nitropropane dioxygenase
Bt4C1_07125	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Bt4C1_07135	COG1696	Membrane protein involved in D-alanine export
Bt4C1_07160	COG0716	FMN binding
Bt4C1_07215	COG1846	Transcriptional regulator
Bt4C1_07225	COG1301	dicarboxylic acid transport
Bt4C1_07230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bt4C1_07235	COG4709	membrane
Bt4C1_07240	COG3874	Sporulation protein YtfJ
Bt4C1_07260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_07265	COG0028	Belongs to the TPP enzyme family
Bt4C1_07270	COG0440	acetolactate synthase activity
Bt4C1_07345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bt4C1_07360	COG1183	phosphatidylcholine synthase activity
Bt4C1_07365	COG1368	sulfuric ester hydrolase activity
Bt4C1_07375	COG0019	diaminopimelate decarboxylase activity
Bt4C1_07395	COG0529	Catalyzes the synthesis of activated sulfate
Bt4C1_07400	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bt4C1_07420	COG1648	precorrin-2 dehydrogenase activity
Bt4C1_07425	COG0733	neurotransmitter:sodium symporter activity
Bt4C1_07445	COG1757	Na H antiporter
Bt4C1_07460	COG4758	membrane
Bt4C1_07465	COG4585	Histidine kinase
Bt4C1_07470	COG2197	response regulator
Bt4C1_07480	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_07525	COG0730	response to heat
Bt4C1_07530	COG0306	phosphate transporter
Bt4C1_07535	COG1392	Phosphate transport regulator
Bt4C1_07540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_07555	COG3852	Histidine kinase
Bt4C1_07560	COG1801	Protein of unknown function DUF72
Bt4C1_07570	COG0582	viral genome integration into host DNA
Bt4C1_07575	COG5002	protein histidine kinase activity
Bt4C1_07590	COG0392	lysyltransferase activity
Bt4C1_07590	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Bt4C1_07605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Bt4C1_07610	COG1686	Belongs to the peptidase S11 family
Bt4C1_07615	COG2715	membrane protein required for spore maturation
Bt4C1_07620	COG0700	Nucleoside recognition
Bt4C1_07625	COG1187	pseudouridine synthase activity
Bt4C1_07635	COG1333	cytochrome c biogenesis protein
Bt4C1_07640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bt4C1_07645	COG0745	RESPONSE REGULATOR receiver
Bt4C1_07650	COG5002	protein histidine kinase activity
Bt4C1_07655	COG2096	Adenosyltransferase
Bt4C1_07660	COG4942	peptidase
Bt4C1_07670	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Bt4C1_07675	COG1141	Ferredoxin
Bt4C1_07685	COG0514	ATP-dependent DNA helicase (RecQ)
Bt4C1_07690	COG1266	CAAX protease self-immunity
Bt4C1_07700	COG1408	metallophosphoesterase
Bt4C1_07705	COG0789	Transcriptional regulator
Bt4C1_07715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bt4C1_07735	COG0492	ferredoxin-NADP+ reductase activity
Bt4C1_07740	COG0252	asparaginase activity
Bt4C1_07805	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bt4C1_07820	COG0142	geranyltranstransferase activity
Bt4C1_07830	COG0142	geranyltranstransferase activity
Bt4C1_07855	COG0457	Tetratricopeptide repeat
Bt4C1_07875	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bt4C1_07880	COG2010	Cytochrome c
Bt4C1_07880	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bt4C1_07885	COG4347	Protein of unknown function (DUF1405)
Bt4C1_07900	COG2738	Putative neutral zinc metallopeptidase
Bt4C1_07910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_07915	COG1694	Mazg nucleotide pyrophosphohydrolase
Bt4C1_07935	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_07970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Bt4C1_07970	COG1199	ATP-dependent helicase activity
Bt4C1_07990	COG3935	DnaD domain protein
Bt4C1_07995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Bt4C1_08005	COG4499	WXG100 protein secretion system (Wss), protein YukC
Bt4C1_08005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_08060	COG0116	Belongs to the methyltransferase superfamily
Bt4C1_08070	COG1199	ATP-dependent helicase activity
Bt4C1_08075	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Bt4C1_08085	COG3173	Aminoglycoside phosphotransferase
Bt4C1_08095	COG0024	Methionine aminopeptidase
Bt4C1_08105	COG2233	PERMEase
Bt4C1_08110	COG2311	Membrane
Bt4C1_08115	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bt4C1_08125	COG0456	acetyltransferase
Bt4C1_08160	COG0754	glutathionylspermidine amidase activity
Bt4C1_08175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_08200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Bt4C1_08215	COG1215	transferase activity, transferring glycosyl groups
Bt4C1_08220	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_08235	COG0454	-acetyltransferase
Bt4C1_08255	COG0328	RNA-DNA hybrid ribonuclease activity
Bt4C1_08290	COG3403	YqcI/YcgG family
Bt4C1_08295	COG1280	lysine exporter protein (LysE YggA)
Bt4C1_08315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_08320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bt4C1_08330	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_08335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bt4C1_08340	COG0789	Transcriptional regulator
Bt4C1_08340	COG4978	Transcriptional regulator
Bt4C1_08350	COG2323	membrane
Bt4C1_08355	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Bt4C1_08390	COG1923	regulation of RNA biosynthetic process
Bt4C1_08400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Bt4C1_08405	COG1360	Flagellar Motor Protein
Bt4C1_08410	COG2201	protein-glutamate methylesterase activity
Bt4C1_08415	COG2198	Histidine kinase
Bt4C1_08415	COG0643	Histidine kinase
Bt4C1_08420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_08420	COG1776	CheC inhibitor of MCP methylation
Bt4C1_08435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bt4C1_08455	COG1256	bacterial-type flagellum assembly
Bt4C1_08460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_08480	COG1815	bacterial-type flagellum-dependent cell motility
Bt4C1_08485	COG1558	bacterial-type flagellum-dependent cell motility
Bt4C1_08490	COG1677	Flagellar hook-basal body complex protein FliE
Bt4C1_08495	COG1766	The M ring may be actively involved in energy transduction
Bt4C1_08500	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_08510	COG1157	protein secretion by the type III secretion system
Bt4C1_08545	COG0784	Response regulator, receiver
Bt4C1_08545	COG0835	chemotaxis
Bt4C1_08555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_08560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_08565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_08570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bt4C1_08575	COG0741	lytic transglycosylase activity
Bt4C1_08585	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_08590	COG1776	CheC inhibitor of MCP methylation
Bt4C1_08590	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bt4C1_08600	COG1338	Plays a role in the flagellum-specific transport system
Bt4C1_08605	COG1987	bacterial-type flagellum assembly
Bt4C1_08615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bt4C1_08620	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bt4C1_08625	COG1419	protein localization to endoplasmic reticulum
Bt4C1_08630	COG4786	Flagellar basal body rod
Bt4C1_08640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Bt4C1_08670	COG2329	Antibiotic biosynthesis monooxygenase
Bt4C1_08705	COG3842	ATPase activity
Bt4C1_08715	COG1177	transmembrane transport
Bt4C1_08720	COG1234	tRNA 3'-trailer cleavage
Bt4C1_08740	COG1686	Belongs to the peptidase S11 family
Bt4C1_08750	COG0406	alpha-ribazole phosphatase activity
Bt4C1_08770	COG1846	Transcriptional regulator
Bt4C1_08780	COG0367	asparagine synthase
Bt4C1_08815	COG0523	cobalamin synthesis protein
Bt4C1_08820	COG0701	Predicted permease
Bt4C1_08835	COG1757	Na H antiporter
Bt4C1_08840	COG0789	Transcriptional regulator
Bt4C1_08870	COG0534	Mate efflux family protein
Bt4C1_08875	COG3340	Belongs to the peptidase S51 family
Bt4C1_08895	COG0785	Cytochrome C biogenesis protein
Bt4C1_08900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_08910	COG0457	Tetratricopeptide repeat
Bt4C1_08930	COG2733	membrane
Bt4C1_08965	COG1131	(ABC) transporter
Bt4C1_08980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_08985	COG0528	UMP kinase activity
Bt4C1_08995	COG1027	Aspartate ammonia-lyase
Bt4C1_09000	COG0281	malic enzyme
Bt4C1_09005	COG4191	Histidine kinase
Bt4C1_09010	COG0784	Response regulator, receiver
Bt4C1_09015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bt4C1_09070	COG1695	Transcriptional regulator
Bt4C1_09080	COG0477	Major facilitator Superfamily
Bt4C1_09090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Bt4C1_09095	COG2223	nitrite transmembrane transporter activity
Bt4C1_09100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_09120	COG0733	neurotransmitter:sodium symporter activity
Bt4C1_09130	COG5566	PFAM Mor transcription activator
Bt4C1_09135	COG2323	membrane
Bt4C1_09155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bt4C1_09165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_09170	COG0028	Belongs to the TPP enzyme family
Bt4C1_09190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Bt4C1_09215	COG2814	Major facilitator Superfamily
Bt4C1_09220	COG3384	dioxygenase
Bt4C1_09235	COG3279	Response regulator of the LytR AlgR family
Bt4C1_09240	COG0427	acetyl-CoA hydrolase
Bt4C1_09260	COG4166	transmembrane transport
Bt4C1_09265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_09285	COG1914	H( )-stimulated, divalent metal cation uptake system
Bt4C1_09300	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bt4C1_09310	COG0531	amino acid
Bt4C1_09330	COG2309	aminopeptidase activity
Bt4C1_09345	COG0456	acetyltransferase
Bt4C1_09360	COG1309	transcriptional regulator
Bt4C1_09365	COG2390	Transcriptional regulator
Bt4C1_09375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_09380	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Bt4C1_09385	COG0295	cytidine deaminase activity
Bt4C1_09395	COG2801	Transposase and inactivated derivatives
Bt4C1_09430	COG4846	Membrane protein involved in cytochrome C biogenesis
Bt4C1_09440	COG0006	proline dipeptidase activity
Bt4C1_09450	COG2132	Multicopper oxidase
Bt4C1_09480	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_09490	COG2372	response to copper ion
Bt4C1_09490	COG1276	copper resistance
Bt4C1_09495	COG4549	nuclear export factor GLE1
Bt4C1_09500	COG0697	spore germination
Bt4C1_09505	COG0583	DNA-binding transcription factor activity
Bt4C1_09510	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_09515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Bt4C1_09520	COG0778	Nitroreductase
Bt4C1_09535	COG0628	permease
Bt4C1_09545	COG1231	oxidoreductase activity
Bt4C1_09550	COG0523	cobalamin synthesis protein
Bt4C1_09560	COG0411	ABC transporter
Bt4C1_09570	COG0559	Belongs to the binding-protein-dependent transport system permease family
Bt4C1_09580	COG0583	DNA-binding transcription factor activity
Bt4C1_09590	COG1942	4-Oxalocrotonate Tautomerase
Bt4C1_09610	COG1271	oxidase subunit
Bt4C1_09615	COG1294	oxidase, subunit
Bt4C1_09620	COG4988	ABC transporter
Bt4C1_09625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Bt4C1_09635	COG1216	Glycosyl transferase, family 2
Bt4C1_09675	COG1686	Belongs to the peptidase S11 family
Bt4C1_09690	COG0791	NLP P60 protein
Bt4C1_09690	COG1388	LysM domain
Bt4C1_09700	COG1132	(ABC) transporter
Bt4C1_09705	COG0745	RESPONSE REGULATOR receiver
Bt4C1_09710	COG5002	protein histidine kinase activity
Bt4C1_09715	COG0300	oxidoreductase activity
Bt4C1_09735	COG0726	polysaccharide deacetylase
Bt4C1_09755	COG0460	homoserine dehydrogenase
Bt4C1_09780	COG1316	TRANSCRIPTIONal
Bt4C1_09795	COG1285	pathogenesis
Bt4C1_09810	COG4264	IucA IucC family
Bt4C1_09815	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_09830	COG1082	Xylose isomerase domain protein TIM barrel
Bt4C1_09840	COG2814	Major facilitator Superfamily
Bt4C1_09845	COG1279	arginine transmembrane transporter activity
Bt4C1_09850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_09860	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bt4C1_09890	COG0577	efflux transmembrane transporter activity
Bt4C1_09895	COG2002	toxin-antitoxin pair type II binding
Bt4C1_09900	COG1404	Belongs to the peptidase S8 family
Bt4C1_09905	COG0640	Transcriptional regulator
Bt4C1_09910	COG0667	Aldo Keto reductase
Bt4C1_09940	COG0840	transmembrane signaling receptor activity
Bt4C1_09955	COG3949	Membrane
Bt4C1_09960	COG0783	Belongs to the Dps family
Bt4C1_09975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bt4C1_09985	COG1231	oxidoreductase activity
Bt4C1_09990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_09995	COG4989	oxidoreductase activity
Bt4C1_10000	COG0523	cobalamin synthesis protein
Bt4C1_10005	COG0456	acetyltransferase
Bt4C1_10010	COG0803	Belongs to the bacterial solute-binding protein 9 family
Bt4C1_10020	COG0702	epimerase
Bt4C1_10030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Bt4C1_10040	COG4166	transmembrane transport
Bt4C1_10055	COG0406	alpha-ribazole phosphatase activity
Bt4C1_10065	COG5337	Spore coat protein CotH
Bt4C1_10070	COG1051	belongs to the nudix hydrolase family
Bt4C1_10075	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_10080	COG2244	polysaccharide biosynthetic process
Bt4C1_10090	COG0701	Predicted permease
Bt4C1_10095	COG3689	TIGRFAM TIGR03943 family protein
Bt4C1_10100	COG1607	acyl-coa hydrolase
Bt4C1_10105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_10120	COG0702	epimerase
Bt4C1_10125	COG2839	Protein conserved in bacteria
Bt4C1_10130	COG1253	flavin adenine dinucleotide binding
Bt4C1_10155	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_10160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bt4C1_10175	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_10185	COG1876	peptidase activity
Bt4C1_10200	COG2211	Major facilitator Superfamily
Bt4C1_10215	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_10225	COG0561	phosphatase activity
Bt4C1_10230	COG1846	Transcriptional regulator
Bt4C1_10235	COG2814	Major facilitator Superfamily
Bt4C1_10245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Bt4C1_10265	COG1819	glycosyl
Bt4C1_10270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_10275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_10305	COG0456	acetyltransferase
Bt4C1_10435	COG3874	Sporulation protein YtfJ
Bt4C1_10460	COG2226	methyltransferase
Bt4C1_10480	COG1082	Xylose isomerase domain protein TIM barrel
Bt4C1_10485	COG0346	lactoylglutathione lyase activity
Bt4C1_10495	COG0604	alcohol dehydrogenase
Bt4C1_10500	COG1595	DNA-templated transcription, initiation
Bt4C1_10510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Bt4C1_10520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Bt4C1_10520	COG0426	domain, Protein
Bt4C1_10530	COG0386	Belongs to the glutathione peroxidase family
Bt4C1_10535	COG1305	Transglutaminase-like
Bt4C1_10540	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
Bt4C1_10545	COG0714	Associated with various cellular activities
Bt4C1_10550	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Bt4C1_10555	COG1140	nitrate reductase beta subunit
Bt4C1_10560	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Bt4C1_10565	COG2181	nitrate reductase activity
Bt4C1_10570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_10575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Bt4C1_10580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_10585	COG0303	'Molybdopterin
Bt4C1_10590	COG0314	molybdopterin synthase activity
Bt4C1_10600	COG2223	nitrite transmembrane transporter activity
Bt4C1_10615	COG1648	precorrin-2 dehydrogenase activity
Bt4C1_10620	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
Bt4C1_10625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Bt4C1_10625	COG1587	Uroporphyrinogen-III synthase
Bt4C1_10630	COG2146	nitrite reductase [NAD(P)H] activity
Bt4C1_10635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Bt4C1_10640	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Bt4C1_10675	COG2359	stage V sporulation protein S
Bt4C1_10690	COG0457	Tetratricopeptide repeat
Bt4C1_10705	COG1418	mRNA catabolic process
Bt4C1_10710	COG0488	(ABC) transporter
Bt4C1_10725	COG0629	single-stranded DNA binding
Bt4C1_10740	COG1413	lyase activity
Bt4C1_10755	COG2521	methyltransferase
Bt4C1_10755	COG2136	Putative SAM-dependent methyltransferase
Bt4C1_10760	COG0018	arginyl-trna synthetase
Bt4C1_10795	COG0017	Asparaginyl-tRNA synthetase
Bt4C1_10800	COG0733	neurotransmitter:sodium symporter activity
Bt4C1_10825	COG2610	gluconate transmembrane transporter activity
Bt4C1_10835	COG1794	racemase activity, acting on amino acids and derivatives
Bt4C1_10845	COG0456	acetyltransferase
Bt4C1_10855	COG3655	Transcriptional regulator
Bt4C1_10860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Bt4C1_10870	COG1131	(ABC) transporter
Bt4C1_10885	COG0546	phosphoglycolate phosphatase activity
Bt4C1_10900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bt4C1_10915	COG0768	penicillin binding
Bt4C1_10925	COG0204	Acyl-transferase
Bt4C1_10930	COG1272	protein, Hemolysin III
Bt4C1_10940	COG0805	protein transport
Bt4C1_10950	COG1307	EDD domain protein, DegV family
Bt4C1_10960	COG1999	signal sequence binding
Bt4C1_10965	COG0071	Belongs to the small heat shock protein (HSP20) family
Bt4C1_10970	COG0367	asparagine synthase
Bt4C1_10985	COG0860	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_10990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_10995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bt4C1_11010	COG1335	isochorismatase
Bt4C1_11015	COG1051	belongs to the nudix hydrolase family
Bt4C1_11020	COG0668	transmembrane transport
Bt4C1_11025	COG2203	Gaf domain
Bt4C1_11025	COG4585	Histidine kinase
Bt4C1_11030	COG2197	response regulator
Bt4C1_11035	COG1737	Transcriptional regulator
Bt4C1_11040	COG0384	phenazine biosynthesis protein PhzF
Bt4C1_11070	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Bt4C1_11105	COG1125	glycine betaine transport
Bt4C1_11105	COG0517	IMP dehydrogenase activity
Bt4C1_11110	COG1174	glycine betaine transport
Bt4C1_11145	COG1253	flavin adenine dinucleotide binding
Bt4C1_11150	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_11155	COG5506	Protein of unknown function (DUF1694)
Bt4C1_11170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bt4C1_11175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Bt4C1_11180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Bt4C1_11185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bt4C1_11190	COG0456	acetyltransferase
Bt4C1_11195	COG3829	transcription factor binding
Bt4C1_11200	COG1509	lysine 2,3-aminomutase activity
Bt4C1_11230	COG4991	sh3 domain protein
Bt4C1_11230	COG0515	serine threonine protein kinase
Bt4C1_11230	COG3064	Membrane
Bt4C1_11240	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_11245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bt4C1_11250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_11325	COG0300	oxidoreductase activity
Bt4C1_11345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_11345	COG4499	WXG100 protein secretion system (Wss), protein YukC
Bt4C1_11355	COG2814	Major facilitator Superfamily
Bt4C1_11360	COG4841	protein insertion into membrane
Bt4C1_11365	COG0372	Belongs to the citrate synthase family
Bt4C1_11370	COG2079	MmgE PrpD family protein
Bt4C1_11375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Bt4C1_11380	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_11385	COG2084	Dehydrogenase
Bt4C1_11395	COG1280	lysine exporter protein (LysE YggA)
Bt4C1_11400	COG1024	Enoyl-CoA hydratase
Bt4C1_11415	COG0420	3'-5' exonuclease activity
Bt4C1_11420	COG0419	ATPase involved in DNA repair
Bt4C1_11440	COG2223	nitrite transmembrane transporter activity
Bt4C1_11445	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_11450	COG1169	isochorismate synthase
Bt4C1_11455	COG1021	2,3-dihydroxybenzoate-AMP ligase
Bt4C1_11460	COG1535	isochorismatase
Bt4C1_11460	COG3433	isochorismatase activity
Bt4C1_11465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Bt4C1_11470	COG3251	PFAM MbtH domain protein
Bt4C1_11475	COG2814	Major facilitator Superfamily
Bt4C1_11490	COG0776	regulation of translation
Bt4C1_11500	COG2318	DinB family
Bt4C1_11510	COG1115	amino acid carrier protein
Bt4C1_11530	COG1187	pseudouridine synthase activity
Bt4C1_11535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bt4C1_11540	COG1136	(ABC) transporter
Bt4C1_11580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_11595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_11630	COG1247	-acetyltransferase
Bt4C1_11665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_11695	COG0583	DNA-binding transcription factor activity
Bt4C1_11700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Bt4C1_11710	COG0583	DNA-binding transcription factor activity
Bt4C1_11715	COG2258	MOSC domain
Bt4C1_11730	COG1132	(ABC) transporter
Bt4C1_11735	COG1132	(ABC) transporter
Bt4C1_11760	COG1396	sequence-specific DNA binding
Bt4C1_11790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bt4C1_11795	COG1595	DNA-templated transcription, initiation
Bt4C1_11820	COG1649	PFAM Uncharacterised BCR, COG1649
Bt4C1_11845	COG2971	BadF BadG BcrA BcrD
Bt4C1_11855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Bt4C1_11865	COG1846	Transcriptional regulator
Bt4C1_11955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_11955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_12040	COG2002	toxin-antitoxin pair type II binding
Bt4C1_12080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bt4C1_12190	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_12255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_12270	COG3615	Tellurite resistance protein tehB
Bt4C1_12270	COG0500	methyltransferase
Bt4C1_12280	COG2226	methyltransferase
Bt4C1_12320	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bt4C1_12345	COG2002	toxin-antitoxin pair type II binding
Bt4C1_12355	COG0730	response to heat
Bt4C1_12365	COG1686	Belongs to the peptidase S11 family
Bt4C1_12380	COG2814	Major facilitator Superfamily
Bt4C1_12410	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_12455	COG0741	lytic transglycosylase activity
Bt4C1_12460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_12470	COG0456	acetyltransferase
Bt4C1_12480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Bt4C1_12485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bt4C1_12490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Bt4C1_12505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bt4C1_12515	COG2234	aminopeptidase activity
Bt4C1_12520	COG2814	Major facilitator Superfamily
Bt4C1_12565	COG1396	sequence-specific DNA binding
Bt4C1_12575	COG0726	polysaccharide deacetylase
Bt4C1_12605	COG0768	penicillin binding
Bt4C1_12610	COG1595	DNA-templated transcription, initiation
Bt4C1_12635	COG1408	metallophosphoesterase
Bt4C1_12645	COG1131	(ABC) transporter
Bt4C1_12655	COG1309	transcriptional regulator
Bt4C1_12670	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_12675	COG0439	Biotin carboxylase
Bt4C1_12680	COG0511	ligase activity, forming carbon-carbon bonds
Bt4C1_12685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Bt4C1_12690	COG1024	Enoyl-CoA hydratase
Bt4C1_12695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Bt4C1_12700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bt4C1_12725	COG1686	Belongs to the peptidase S11 family
Bt4C1_12755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bt4C1_12770	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_12775	COG2207	Transcriptional regulator
Bt4C1_12805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Bt4C1_12815	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_12820	COG1733	regulation of RNA biosynthetic process
Bt4C1_12865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_12880	COG1063	alcohol dehydrogenase
Bt4C1_12890	COG2323	membrane
Bt4C1_12900	COG0693	protein deglycase activity
Bt4C1_12910	COG3386	PFAM SMP-30 Gluconolaconase
Bt4C1_12915	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Bt4C1_12920	COG3773	Cell wall hydrolase
Bt4C1_12930	COG0745	RESPONSE REGULATOR receiver
Bt4C1_12935	COG2205	protein histidine kinase activity
Bt4C1_12940	COG0583	DNA-binding transcription factor activity
Bt4C1_12945	COG0667	Aldo Keto reductase
Bt4C1_12965	COG1136	(ABC) transporter
Bt4C1_12970	COG0577	efflux transmembrane transporter activity
Bt4C1_12995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_13005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Bt4C1_13060	COG2124	cytochrome p450
Bt4C1_13095	COG0561	phosphatase activity
Bt4C1_13100	COG5002	protein histidine kinase activity
Bt4C1_13115	COG1819	glycosyl
Bt4C1_13120	COG1794	racemase activity, acting on amino acids and derivatives
Bt4C1_13140	COG2205	protein histidine kinase activity
Bt4C1_13185	COG2169	Transcriptional regulator
Bt4C1_13215	COG0604	alcohol dehydrogenase
Bt4C1_13220	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_13255	COG1307	EDD domain protein, DegV family
Bt4C1_13300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_13305	COG0697	spore germination
Bt4C1_13330	COG0494	nUDIX hydrolase
Bt4C1_13350	COG2223	nitrite transmembrane transporter activity
Bt4C1_13365	COG0592	DNA-directed DNA polymerase activity
Bt4C1_13370	COG1051	belongs to the nudix hydrolase family
Bt4C1_13385	COG3878	Protein conserved in bacteria
Bt4C1_13405	COG4667	esterase of the alpha-beta hydrolase superfamily
Bt4C1_13445	COG0322	excinuclease ABC activity
Bt4C1_13480	COG1819	glycosyl
Bt4C1_13485	COG1819	glycosyl
Bt4C1_13500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_13530	COG0745	RESPONSE REGULATOR receiver
Bt4C1_13535	COG5002	protein histidine kinase activity
Bt4C1_13550	COG1136	(ABC) transporter
Bt4C1_13555	COG0577	efflux transmembrane transporter activity
Bt4C1_13560	COG1073	alpha beta
Bt4C1_13570	COG0076	glutamate decarboxylase activity
Bt4C1_13585	COG1523	belongs to the glycosyl hydrolase 13 family
Bt4C1_13590	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_13595	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_13615	COG0201	protein transport
Bt4C1_13620	COG0697	spore germination
Bt4C1_13625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_13660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_13675	COG2959	enzyme of heme biosynthesis
Bt4C1_13680	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_13680	COG3773	Cell wall hydrolase
Bt4C1_13715	COG1309	transcriptional regulator
Bt4C1_13730	COG3284	Transcriptional regulator
Bt4C1_13745	COG1349	DNA-binding transcription factor activity
Bt4C1_13760	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_13775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bt4C1_13780	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bt4C1_13785	COG0022	dehydrogenase e1 component
Bt4C1_13790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bt4C1_13800	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_13830	COG4176	ABC-type proline glycine betaine transport system permease component
Bt4C1_13835	COG0517	IMP dehydrogenase activity
Bt4C1_13835	COG4175	Glycine betaine
Bt4C1_13865	COG2153	protein acetylation
Bt4C1_13885	COG3397	chitin binding
Bt4C1_13890	COG1819	glycosyl
Bt4C1_13900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Bt4C1_13910	COG2205	protein histidine kinase activity
Bt4C1_13915	COG2267	carboxylic ester hydrolase activity
Bt4C1_13915	COG2226	methyltransferase
Bt4C1_13920	COG2315	Protein conserved in bacteria
Bt4C1_13970	COG0456	acetyltransferase
Bt4C1_13975	COG3973	AAA domain
Bt4C1_13990	COG0514	ATP-dependent DNA helicase (RecQ)
Bt4C1_14020	COG4637	Psort location Cytoplasmic, score
Bt4C1_14045	COG3397	chitin binding
Bt4C1_14060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Bt4C1_14065	COG1115	amino acid carrier protein
Bt4C1_14070	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_14075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Bt4C1_14085	COG3938	Belongs to the proline racemase family
Bt4C1_14090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bt4C1_14135	COG1078	dGTPase activity
Bt4C1_14140	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_14150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Bt4C1_14155	COG4166	transmembrane transport
Bt4C1_14165	COG4948	Mandelate Racemase Muconate Lactonizing
Bt4C1_14180	COG0667	Aldo Keto reductase
Bt4C1_14225	COG5002	protein histidine kinase activity
Bt4C1_14225	COG3850	Histidine kinase
Bt4C1_14230	COG0745	RESPONSE REGULATOR receiver
Bt4C1_14255	COG1164	Oligoendopeptidase f
Bt4C1_14260	COG1307	EDD domain protein, DegV family
Bt4C1_14300	COG2814	Major facilitator Superfamily
Bt4C1_14310	COG1664	Polymer-forming cytoskeletal
Bt4C1_14315	COG0789	Transcriptional regulator
Bt4C1_14320	COG4533	DNA binding
Bt4C1_14325	COG2814	Major facilitator Superfamily
Bt4C1_14325	COG0477	Major facilitator Superfamily
Bt4C1_14345	COG2261	transglycosylase associated protein
Bt4C1_14360	COG2226	methyltransferase
Bt4C1_14395	COG0436	Aminotransferase
Bt4C1_14400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Bt4C1_14410	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Bt4C1_14470	COG0628	permease
Bt4C1_14485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_14490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_14520	COG2746	aminoglycoside 3-N-acetyltransferase activity
Bt4C1_14530	COG0697	spore germination
Bt4C1_14535	COG2318	DinB family
Bt4C1_14555	COG4912	Dna alkylation repair
Bt4C1_14560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_14565	COG0346	lactoylglutathione lyase activity
Bt4C1_14570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_14580	COG0726	polysaccharide deacetylase
Bt4C1_14600	COG0861	Integral membrane protein TerC family
Bt4C1_14605	COG1368	sulfuric ester hydrolase activity
Bt4C1_14610	COG0488	(ABC) transporter
Bt4C1_14615	COG2409	Drug exporters of the RND superfamily
Bt4C1_14615	COG1033	growth of symbiont in host cell
Bt4C1_14620	COG1309	transcriptional regulator
Bt4C1_14635	COG0287	Prephenate dehydrogenase
Bt4C1_14650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bt4C1_14650	COG1605	Chorismate mutase
Bt4C1_14685	COG3584	3D domain protein
Bt4C1_14685	COG1388	LysM domain
Bt4C1_14715	COG1879	ABC-type sugar transport system periplasmic component
Bt4C1_14725	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bt4C1_14735	COG2390	Transcriptional regulator
Bt4C1_14740	COG1070	Carbohydrate kinase
Bt4C1_14765	COG2329	Antibiotic biosynthesis monooxygenase
Bt4C1_14780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_14795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_14800	COG4187	Peptidase family M20/M25/M40
Bt4C1_14805	COG1414	Transcriptional regulator
Bt4C1_14810	COG0833	amino acid
Bt4C1_14820	COG1690	Belongs to the RtcB family
Bt4C1_14825	COG3239	Fatty acid desaturase
Bt4C1_14835	COG2720	vancomycin resistance protein
Bt4C1_14840	COG1785	Belongs to the alkaline phosphatase family
Bt4C1_14850	COG3655	Transcriptional regulator
Bt4C1_14875	COG0346	lactoylglutathione lyase activity
Bt4C1_14895	COG0714	Associated with various cellular activities
Bt4C1_14920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bt4C1_14925	COG0753	catalase activity
Bt4C1_14955	COG5444	nuclease activity
Bt4C1_14995	COG0778	Nitroreductase
Bt4C1_15000	COG1846	Transcriptional regulator
Bt4C1_15020	COG3831	ATPase activity
Bt4C1_15020	COG4884	unkown
Bt4C1_15030	COG1136	(ABC) transporter
Bt4C1_15050	COG2207	Transcriptional regulator
Bt4C1_15055	COG0456	acetyltransferase
Bt4C1_15065	COG2816	NAD+ diphosphatase activity
Bt4C1_15070	COG0697	spore germination
Bt4C1_15075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_15115	COG0730	response to heat
Bt4C1_15125	COG0833	amino acid
Bt4C1_15170	COG1329	Transcriptional regulator
Bt4C1_15180	COG5002	protein histidine kinase activity
Bt4C1_15235	COG1984	allophanate hydrolase subunit 2
Bt4C1_15240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Bt4C1_15245	COG1414	Transcriptional regulator
Bt4C1_15260	COG0640	Transcriptional regulator
Bt4C1_15270	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_15305	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
Bt4C1_15325	COG3848	Pyruvate phosphate dikinase
Bt4C1_15325	COG0574	Belongs to the PEP-utilizing enzyme family
Bt4C1_15330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_15350	COG1063	alcohol dehydrogenase
Bt4C1_15365	COG0252	asparaginase activity
Bt4C1_15370	COG1396	sequence-specific DNA binding
Bt4C1_15390	COG5002	protein histidine kinase activity
Bt4C1_15415	COG2207	Transcriptional regulator
Bt4C1_15420	COG0322	excinuclease ABC activity
Bt4C1_15425	COG0531	amino acid
Bt4C1_15430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_15440	COG0531	amino acid
Bt4C1_15445	COG0697	spore germination
Bt4C1_15450	COG0784	Response regulator, receiver
Bt4C1_15455	COG4191	Histidine kinase
Bt4C1_15465	COG1115	amino acid carrier protein
Bt4C1_15475	COG2124	cytochrome p450
Bt4C1_15495	COG2267	carboxylic ester hydrolase activity
Bt4C1_15500	COG1335	isochorismatase
Bt4C1_15520	COG0583	DNA-binding transcription factor activity
Bt4C1_15525	COG1846	Transcriptional regulator
Bt4C1_15530	COG0598	Magnesium transport protein CorA
Bt4C1_15550	COG1073	alpha beta
Bt4C1_15570	COG0415	Belongs to the DNA photolyase family
Bt4C1_15575	COG0288	reversible hydration of carbon dioxide
Bt4C1_15585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Bt4C1_15590	COG5609	conserved protein (DUF2294)
Bt4C1_15595	COG0726	polysaccharide deacetylase
Bt4C1_15605	COG1575	Belongs to the MenA family. Type 1 subfamily
Bt4C1_15610	COG0803	Belongs to the bacterial solute-binding protein 9 family
Bt4C1_15615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bt4C1_15620	COG1121	(ABC) transporter
Bt4C1_15640	COG0798	PFAM Bile acid sodium symporter
Bt4C1_15645	COG0346	lactoylglutathione lyase activity
Bt4C1_15650	COG0640	Transcriptional regulator
Bt4C1_15670	COG0346	lactoylglutathione lyase activity
Bt4C1_15695	COG0745	RESPONSE REGULATOR receiver
Bt4C1_15700	COG3850	Histidine kinase
Bt4C1_15700	COG5002	protein histidine kinase activity
Bt4C1_15735	COG0277	FAD linked oxidase domain protein
Bt4C1_15745	COG1136	(ABC) transporter
Bt4C1_15780	COG2814	Major facilitator Superfamily
Bt4C1_15795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Bt4C1_15810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Bt4C1_15830	COG0577	efflux transmembrane transporter activity
Bt4C1_15835	COG5002	protein histidine kinase activity
Bt4C1_15835	COG3850	Histidine kinase
Bt4C1_15850	COG1846	Transcriptional regulator
Bt4C1_15855	COG0456	acetyltransferase
Bt4C1_15860	COG2808	Putative FMN-binding domain
Bt4C1_15865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_15880	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bt4C1_15900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Bt4C1_15920	COG0662	Cupin 2, conserved barrel domain protein
Bt4C1_15925	COG2207	Transcriptional regulator
Bt4C1_15925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_15940	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_15940	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_15955	COG2814	Major facilitator Superfamily
Bt4C1_16010	COG4282	regulation of fungal-type cell wall biogenesis
Bt4C1_16065	COG5444	nuclease activity
Bt4C1_16090	COG1876	peptidase activity
Bt4C1_16095	COG2843	Capsule synthesis protein
Bt4C1_16105	COG0477	Major facilitator Superfamily
Bt4C1_16120	COG1846	Transcriptional regulator
Bt4C1_16125	COG2814	Major facilitator Superfamily
Bt4C1_16135	COG2031	fatty acid transporter
Bt4C1_16145	COG2249	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_16200	COG1288	antiporter activity
Bt4C1_16205	COG2356	endonuclease I
Bt4C1_16215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bt4C1_16220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Bt4C1_16240	COG1733	regulation of RNA biosynthetic process
Bt4C1_16245	COG0778	Nitroreductase
Bt4C1_16275	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_16285	COG1131	(ABC) transporter
Bt4C1_16310	COG1011	Hydrolase
Bt4C1_16330	COG1051	belongs to the nudix hydrolase family
Bt4C1_16340	COG0346	lactoylglutathione lyase activity
Bt4C1_16345	COG1940	carbohydrate kinase activity
Bt4C1_16350	COG0738	Major facilitator superfamily
Bt4C1_16355	COG0110	maltose O-acetyltransferase activity
Bt4C1_16360	COG0180	Tryptophanyl-tRNA synthetase
Bt4C1_16370	COG0628	permease
Bt4C1_16405	COG0500	methyltransferase
Bt4C1_16415	COG0477	Major facilitator Superfamily
Bt4C1_16445	COG1253	flavin adenine dinucleotide binding
Bt4C1_16450	COG0789	Transcriptional regulator
Bt4C1_16455	COG0697	spore germination
Bt4C1_16470	COG1357	PFAM Pentapeptide repeats (8 copies)
Bt4C1_16475	COG3813	Protein conserved in bacteria
Bt4C1_16480	COG2706	6-phosphogluconolactonase activity
Bt4C1_16485	COG1070	Carbohydrate kinase
Bt4C1_16490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Bt4C1_16495	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Bt4C1_16500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Bt4C1_16505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Bt4C1_16520	COG0814	amino acid
Bt4C1_16545	COG1393	Belongs to the ArsC family
Bt4C1_16550	COG1733	regulation of RNA biosynthetic process
Bt4C1_16555	COG2188	Transcriptional regulator
Bt4C1_16560	COG0673	inositol 2-dehydrogenase activity
Bt4C1_16580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_16605	COG0384	phenazine biosynthesis protein PhzF
Bt4C1_16615	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_16620	COG2249	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_16625	COG1733	regulation of RNA biosynthetic process
Bt4C1_16630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Bt4C1_16645	COG0726	polysaccharide deacetylase
Bt4C1_16655	COG1191	sigma factor activity
Bt4C1_16700	COG1151	hydroxylamine reductase activity
Bt4C1_16730	COG2072	flavoprotein involved in K transport
Bt4C1_16760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_16765	COG0604	alcohol dehydrogenase
Bt4C1_16770	COG1113	amino acid transport
Bt4C1_16775	COG2814	Major facilitator Superfamily
Bt4C1_16805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bt4C1_16810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bt4C1_16820	COG1247	-acetyltransferase
Bt4C1_16825	COG3739	integral membrane protein
Bt4C1_16855	COG0583	DNA-binding transcription factor activity
Bt4C1_16875	COG1193	negative regulation of DNA recombination
Bt4C1_16890	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Bt4C1_16895	COG1164	Oligoendopeptidase f
Bt4C1_16900	COG2957	Belongs to the agmatine deiminase family
Bt4C1_16925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Bt4C1_16935	COG2271	Major facilitator Superfamily
Bt4C1_16950	COG0584	glycerophosphoryl diester phosphodiesterase
Bt4C1_16960	COG0640	Transcriptional regulator
Bt4C1_16965	COG0604	alcohol dehydrogenase
Bt4C1_16975	COG0457	Tetratricopeptide repeat
Bt4C1_16985	COG0385	Bile acid
Bt4C1_16990	COG0277	FAD linked oxidase domain protein
Bt4C1_17010	COG1252	NADH dehydrogenase
Bt4C1_17025	COG4641	Protein conserved in bacteria
Bt4C1_17035	COG2089	acid synthase
Bt4C1_17050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Bt4C1_17055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Bt4C1_17060	COG1088	dTDP-glucose 4,6-dehydratase activity
Bt4C1_17070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Bt4C1_17075	COG0463	Glycosyl transferase, family 2
Bt4C1_17080	COG0463	Glycosyl transferase, family 2
Bt4C1_17090	COG0823	Involved in the tonB-independent uptake of proteins
Bt4C1_17095	COG3397	chitin binding
Bt4C1_17105	COG0697	spore germination
Bt4C1_17125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Bt4C1_17145	COG0457	Tetratricopeptide repeat
Bt4C1_17205	COG1309	transcriptional regulator
Bt4C1_17220	COG1876	peptidase activity
Bt4C1_17245	COG3852	Histidine kinase
Bt4C1_17255	COG1285	pathogenesis
Bt4C1_17265	COG2514	catechol 2,3-dioxygenase activity
Bt4C1_17270	COG2720	vancomycin resistance protein
Bt4C1_17295	COG1278	Cold shock
Bt4C1_17305	COG0716	FMN binding
Bt4C1_17315	COG0494	nUDIX hydrolase
Bt4C1_17335	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_17345	COG0165	Argininosuccinate lyase
Bt4C1_17360	COG4145	pantothenate transmembrane transporter activity
Bt4C1_17370	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_17375	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_17385	COG1657	PFAM Prenyltransferase squalene oxidase
Bt4C1_17390	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Bt4C1_17395	COG2962	Rard protein
Bt4C1_17400	COG3326	Membrane
Bt4C1_17415	COG0489	protein tyrosine kinase activity
Bt4C1_17425	COG0314	molybdopterin synthase activity
Bt4C1_17430	COG0303	'Molybdopterin
Bt4C1_17435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_17440	COG2116	formate transmembrane transporter activity
Bt4C1_17450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Bt4C1_17455	COG5609	conserved protein (DUF2294)
Bt4C1_17460	COG2427	Protein of unknown function (DUF1641)
Bt4C1_17465	COG3383	formate dehydrogenase (NAD+) activity
Bt4C1_17470	COG0697	spore germination
Bt4C1_17515	COG2226	methyltransferase
Bt4C1_17520	COG4166	transmembrane transport
Bt4C1_17530	COG4166	transmembrane transport
Bt4C1_17535	COG1301	dicarboxylic acid transport
Bt4C1_17540	COG1316	TRANSCRIPTIONal
Bt4C1_17550	COG1595	DNA-templated transcription, initiation
Bt4C1_17560	COG1131	(ABC) transporter
Bt4C1_17580	COG0673	inositol 2-dehydrogenase activity
Bt4C1_17585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bt4C1_17590	COG0187	DNA topoisomerase II activity
Bt4C1_17595	COG1832	CoA-binding protein
Bt4C1_17600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bt4C1_17605	COG0745	RESPONSE REGULATOR receiver
Bt4C1_17625	COG4841	protein insertion into membrane
Bt4C1_17630	COG0824	Thioesterase
Bt4C1_17655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_17665	COG1132	(ABC) transporter
Bt4C1_17670	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Bt4C1_17680	COG0726	polysaccharide deacetylase
Bt4C1_17700	COG2211	Major facilitator Superfamily
Bt4C1_17710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Bt4C1_17725	COG0183	Belongs to the thiolase family
Bt4C1_17730	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_17735	COG1268	BioY protein
Bt4C1_17740	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_17745	COG1396	sequence-specific DNA binding
Bt4C1_17780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_17790	COG5002	protein histidine kinase activity
Bt4C1_17795	COG0400	carboxylic ester hydrolase activity
Bt4C1_17800	COG0346	lactoylglutathione lyase activity
Bt4C1_17805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bt4C1_17815	COG0069	glutamate synthase activity
Bt4C1_17820	COG1902	pentaerythritol trinitrate reductase activity
Bt4C1_17825	COG1329	Transcriptional regulator
Bt4C1_17830	COG0010	Belongs to the arginase family
Bt4C1_17880	COG4846	Membrane protein involved in cytochrome C biogenesis
Bt4C1_17885	COG0785	Cytochrome C biogenesis protein
Bt4C1_17905	COG1131	(ABC) transporter
Bt4C1_17925	COG0583	DNA-binding transcription factor activity
Bt4C1_17935	COG1346	cytolysis
Bt4C1_17950	COG0730	response to heat
Bt4C1_17975	COG1132	(ABC) transporter
Bt4C1_17980	COG1132	(ABC) transporter
Bt4C1_18015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_18020	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_18030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bt4C1_18050	COG1695	Transcriptional regulator
Bt4C1_18060	COG0741	lytic transglycosylase activity
Bt4C1_18060	COG0739	heme binding
Bt4C1_18060	COG1196	nuclear chromosome segregation
Bt4C1_18065	COG0741	lytic transglycosylase activity
Bt4C1_18100	COG0174	glutamine synthetase
Bt4C1_18105	COG0789	Transcriptional regulator
Bt4C1_18110	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Bt4C1_18115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Bt4C1_18120	COG2860	membrane
Bt4C1_18130	COG0464	growth
Bt4C1_18160	COG3584	3D domain protein
Bt4C1_18160	COG1388	LysM domain
Bt4C1_18165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bt4C1_18165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bt4C1_18165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bt4C1_18170	COG1105	Belongs to the carbohydrate kinase PfkB family
Bt4C1_18175	COG1349	DNA-binding transcription factor activity
Bt4C1_18180	COG1979	alcohol dehydrogenase
Bt4C1_18185	COG2322	membrane
Bt4C1_18200	COG1113	amino acid transport
Bt4C1_18215	COG1408	metallophosphoesterase
Bt4C1_18235	COG2217	Heavy metal translocating P-type atpase
Bt4C1_18240	COG2608	mercury ion transmembrane transporter activity
Bt4C1_18245	COG1937	Protein conserved in bacteria
Bt4C1_18265	COG2819	hydrolase of the alpha beta superfamily
Bt4C1_18270	COG1120	ATPase activity
Bt4C1_18275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_18280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_18285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_18290	COG0708	Exodeoxyribonuclease III
Bt4C1_18295	COG2169	Transcriptional regulator
Bt4C1_18300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Bt4C1_18305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Bt4C1_18315	COG2364	Membrane
Bt4C1_18330	COG2267	carboxylic ester hydrolase activity
Bt4C1_18335	COG3300	MHYT domain
Bt4C1_18335	COG5001	Diguanylate cyclase
Bt4C1_18370	COG1346	cytolysis
Bt4C1_18380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Bt4C1_18395	COG0840	transmembrane signaling receptor activity
Bt4C1_18400	COG0823	Involved in the tonB-independent uptake of proteins
Bt4C1_18405	COG1404	Belongs to the peptidase S8 family
Bt4C1_18410	COG3773	Cell wall hydrolase
Bt4C1_18420	COG1368	sulfuric ester hydrolase activity
Bt4C1_18425	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bt4C1_18450	COG4550	Control of competence regulator ComK, YlbF/YmcA
Bt4C1_18460	COG1013	pyruvate-flavodoxin oxidoreductase activity
Bt4C1_18465	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bt4C1_18465	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Bt4C1_18475	COG2359	stage V sporulation protein S
Bt4C1_18480	COG1692	metallophosphoesterase
Bt4C1_18505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Bt4C1_18510	COG1426	Protein conserved in bacteria
Bt4C1_18525	COG0300	oxidoreductase activity
Bt4C1_18530	COG0612	Peptidase, M16
Bt4C1_18535	COG0612	Peptidase, M16
Bt4C1_18560	COG2188	Transcriptional regulator
Bt4C1_18575	COG0740	serine-type endopeptidase activity
Bt4C1_18580	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bt4C1_18590	COG0527	aspartate kinase activity
Bt4C1_18595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Bt4C1_18600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bt4C1_18605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bt4C1_18610	COG1873	PFAM PRC-barrel domain
Bt4C1_18615	COG0612	Peptidase, M16
Bt4C1_18620	COG0726	polysaccharide deacetylase
Bt4C1_18635	COG0196	riboflavin kinase activity
Bt4C1_18650	COG1550	Protein conserved in bacteria
Bt4C1_18660	COG1358	cellular component organization or biogenesis
Bt4C1_18665	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Bt4C1_18670	COG0195	Participates in both transcription termination and antitermination
Bt4C1_18690	COG0750	zinc metalloprotease
Bt4C1_18700	COG4589	Belongs to the CDS family
Bt4C1_18745	COG4974	Belongs to the 'phage' integrase family
Bt4C1_18755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bt4C1_18760	COG0758	DNA mediated transformation
Bt4C1_18765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Bt4C1_18805	COG1837	Belongs to the UPF0109 family
Bt4C1_18815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Bt4C1_18825	COG0552	protein localization to endoplasmic reticulum
Bt4C1_18830	COG1196	nuclear chromosome segregation
Bt4C1_18845	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_18850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Bt4C1_18865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Bt4C1_18870	COG1461	Dihydroxyacetone kinase
Bt4C1_18875	COG1302	Protein conserved in bacteria
Bt4C1_18890	COG1564	THIamine pyrophosphokinase
Bt4C1_18895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Bt4C1_18905	COG0515	serine threonine protein kinase
Bt4C1_18905	COG2815	serine threonine protein kinase
Bt4C1_18910	COG0631	protein serine/threonine phosphatase activity
Bt4C1_18920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Bt4C1_18920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Bt4C1_18935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Bt4C1_18940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bt4C1_18960	COG1561	YicC-like family, N-terminal region
Bt4C1_18965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Bt4C1_19000	COG3069	C4-dicarboxylate transmembrane transporter activity
Bt4C1_19060	COG0564	pseudouridine synthase activity
Bt4C1_19080	COG3599	regulation of cell shape
Bt4C1_19085	COG2302	S4 RNA-binding domain
Bt4C1_19090	COG0762	integral membrane protein
Bt4C1_19100	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Bt4C1_19110	COG1873	PFAM PRC-barrel domain
Bt4C1_19115	COG1191	sigma factor activity
Bt4C1_19120	COG1191	sigma factor activity
Bt4C1_19130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Bt4C1_19135	COG0849	cell division
Bt4C1_19150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Bt4C1_19155	COG0772	Belongs to the SEDS family
Bt4C1_19175	COG0768	penicillin binding
Bt4C1_19200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bt4C1_19220	COG1399	metal-binding, possibly nucleic acid-binding protein
Bt4C1_19230	COG3480	Lon protease (S16) C-terminal proteolytic domain
Bt4C1_19235	COG1752	Esterase of the alpha-beta hydrolase superfamily
Bt4C1_19240	COG3314	Sporulation integral membrane protein YlbJ
Bt4C1_19250	COG0742	ribosomal rna small subunit methyltransferase
Bt4C1_19265	COG3679	Belongs to the UPF0342 family
Bt4C1_19270	COG0406	alpha-ribazole phosphatase activity
Bt4C1_19285	COG2340	Cysteine-rich secretory protein family
Bt4C1_19300	COG3336	cytochrome c oxidase
Bt4C1_19335	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Bt4C1_19340	COG0772	Belongs to the SEDS family
Bt4C1_19350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Bt4C1_19355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Bt4C1_19365	COG4896	Protein conserved in bacteria
Bt4C1_19390	COG0483	inositol monophosphate 1-phosphatase activity
Bt4C1_19410	COG1982	Orn Lys Arg decarboxylase major
Bt4C1_19460	COG0022	dehydrogenase e1 component
Bt4C1_19465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bt4C1_19480	COG0561	phosphatase activity
Bt4C1_19490	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bt4C1_19495	COG0569	domain protein
Bt4C1_19515	COG0583	DNA-binding transcription factor activity
Bt4C1_19520	COG0517	IMP dehydrogenase activity
Bt4C1_19530	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Bt4C1_19540	COG4703	Protein of unknown function (DUF1797)
Bt4C1_19555	COG2200	EAL domain
Bt4C1_19560	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_19565	COG1408	metallophosphoesterase
Bt4C1_19610	COG2814	Major facilitator Superfamily
Bt4C1_19630	COG3209	COG3209 Rhs family protein
Bt4C1_19640	COG2205	protein histidine kinase activity
Bt4C1_19650	COG0436	Aminotransferase
Bt4C1_19655	COG1609	Transcriptional regulator
Bt4C1_19660	COG3833	ABC-type maltose transport systems, permease component
Bt4C1_19665	COG1175	transmembrane transport
Bt4C1_19670	COG2182	Extracellular solute-binding protein
Bt4C1_19680	COG0366	Alpha amylase catalytic
Bt4C1_19685	COG3842	ATPase activity
Bt4C1_19725	COG0183	Belongs to the thiolase family
Bt4C1_19755	COG1695	Transcriptional regulator
Bt4C1_19760	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_19780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Bt4C1_19785	COG0436	Aminotransferase
Bt4C1_19820	COG2084	Dehydrogenase
Bt4C1_19830	COG2199	diguanylate cyclase activity
Bt4C1_19830	COG2203	Gaf domain
Bt4C1_19835	COG0778	Nitroreductase
Bt4C1_19860	COG1263	PTS System
Bt4C1_19860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bt4C1_19860	COG2190	(PTS) system
Bt4C1_19865	COG3711	transcriptional antiterminator
Bt4C1_19885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Bt4C1_19910	COG1547	Domain of unknown function (DUF309)
Bt4C1_19915	COG0456	acetyltransferase
Bt4C1_19920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Bt4C1_19925	COG4086	secreted protein
Bt4C1_19930	COG0561	phosphatase activity
Bt4C1_19935	COG0697	spore germination
Bt4C1_19950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bt4C1_19995	COG1686	Belongs to the peptidase S11 family
Bt4C1_20000	COG1725	Transcriptional regulator
Bt4C1_20005	COG1131	(ABC) transporter
Bt4C1_20025	COG1846	Transcriptional regulator
Bt4C1_20040	COG0598	Magnesium transport protein CorA
Bt4C1_20065	COG4974	Belongs to the 'phage' integrase family
Bt4C1_20075	COG0735	belongs to the Fur family
Bt4C1_20080	COG1300	Membrane
Bt4C1_20100	COG0667	Aldo Keto reductase
Bt4C1_20105	COG0656	L-ascorbic acid biosynthetic process
Bt4C1_20110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Bt4C1_20110	COG0456	acetyltransferase
Bt4C1_20120	COG4085	toxin activity
Bt4C1_20120	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_20120	COG1525	nuclease
Bt4C1_20130	COG0596	Alpha beta hydrolase
Bt4C1_20135	COG2056	Na+-H+ antiporter family
Bt4C1_20140	COG1609	Transcriptional regulator
Bt4C1_20145	COG0456	acetyltransferase
Bt4C1_20150	COG1073	alpha beta
Bt4C1_20165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bt4C1_20165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bt4C1_20170	COG0307	riboflavin synthase, alpha
Bt4C1_20200	COG1073	alpha beta
Bt4C1_20200	COG2226	methyltransferase
Bt4C1_20215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Bt4C1_20230	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_20240	COG1522	sequence-specific DNA binding
Bt4C1_20285	COG0300	oxidoreductase activity
Bt4C1_20290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_20295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_20300	COG1760	l-serine dehydratase
Bt4C1_20305	COG1760	l-serine dehydratase
Bt4C1_20330	COG1285	pathogenesis
Bt4C1_20340	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bt4C1_20345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_20355	COG1376	ErfK ybiS ycfS ynhG family protein
Bt4C1_20360	COG4129	membrane
Bt4C1_20365	COG1126	abc transporter atp-binding protein
Bt4C1_20370	COG0765	amino acid transport
Bt4C1_20375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bt4C1_20395	COG2323	membrane
Bt4C1_20400	COG0772	Belongs to the SEDS family
Bt4C1_20405	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bt4C1_20410	COG0022	dehydrogenase e1 component
Bt4C1_20415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bt4C1_20420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bt4C1_20430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bt4C1_20435	COG0280	phosphate acetyltransferase
Bt4C1_20445	COG3829	transcription factor binding
Bt4C1_20445	COG3290	protein histidine kinase activity
Bt4C1_20455	COG0584	glycerophosphoryl diester phosphodiesterase
Bt4C1_20460	COG3093	addiction module antidote protein HigA
Bt4C1_20475	COG0750	zinc metalloprotease
Bt4C1_20480	COG0497	DNA recombination
Bt4C1_20490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Bt4C1_20500	COG0142	geranyltranstransferase activity
Bt4C1_20525	COG1302	Protein conserved in bacteria
Bt4C1_20530	COG0439	Biotin carboxylase
Bt4C1_20535	COG0511	ligase activity, forming carbon-carbon bonds
Bt4C1_20575	COG3854	ATPases associated with a variety of cellular activities
Bt4C1_20600	COG0006	proline dipeptidase activity
Bt4C1_20615	COG3872	metal-dependent enzyme
Bt4C1_20625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Bt4C1_20660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_20670	COG1609	Transcriptional regulator
Bt4C1_20680	COG2076	Multidrug Resistance protein
Bt4C1_20685	COG2076	Multidrug Resistance protein
Bt4C1_20715	COG1131	(ABC) transporter
Bt4C1_20720	COG1725	Transcriptional regulator
Bt4C1_20750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bt4C1_20815	COG1459	type II secretion system
Bt4C1_20820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bt4C1_20875	COG0646	methionine synthase
Bt4C1_20875	COG1410	methionine synthase
Bt4C1_20880	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Bt4C1_20880	COG0646	methionine synthase
Bt4C1_20885	COG0626	cystathionine gamma-synthase activity
Bt4C1_20890	COG0626	cystathionine gamma-synthase activity
Bt4C1_20910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_20915	COG1940	carbohydrate kinase activity
Bt4C1_20920	COG4483	Protein conserved in bacteria
Bt4C1_20925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Bt4C1_20935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Bt4C1_20940	COG0704	Plays a role in the regulation of phosphate uptake
Bt4C1_20950	COG0573	inorganic phosphate transmembrane transporter activity
Bt4C1_20955	COG0573	inorganic phosphate transmembrane transporter activity
Bt4C1_20970	COG0477	Major facilitator Superfamily
Bt4C1_20975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Bt4C1_20985	COG5521	maltodextrose utilization protein MalA
Bt4C1_21000	COG0735	belongs to the Fur family
Bt4C1_21005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bt4C1_21010	COG1121	(ABC) transporter
Bt4C1_21015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_21045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Bt4C1_21050	COG2384	SAM-dependent methyltransferase
Bt4C1_21060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Bt4C1_21065	COG0358	DNA primase activity
Bt4C1_21075	COG0517	IMP dehydrogenase activity
Bt4C1_21090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Bt4C1_21095	COG0295	cytidine deaminase activity
Bt4C1_21100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Bt4C1_21110	COG1480	7TM receptor with intracellular HD hydrolase
Bt4C1_21115	COG1702	phosphate starvation-inducible protein PhoH
Bt4C1_21130	COG1610	YqeY-like protein
Bt4C1_21140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bt4C1_21145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Bt4C1_21175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bt4C1_21180	COG1733	regulation of RNA biosynthetic process
Bt4C1_21205	COG1466	dna polymerase III delta subunit
Bt4C1_21215	COG2333	competence protein COMEC
Bt4C1_21215	COG0658	competence protein
Bt4C1_21220	COG2131	deaminase
Bt4C1_21225	COG1555	photosystem II stabilization
Bt4C1_21225	COG1596	polysaccharide export
Bt4C1_21230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bt4C1_21235	COG2226	methyltransferase
Bt4C1_21240	COG0799	negative regulation of ribosome biogenesis
Bt4C1_21245	COG1713	HD superfamily hydrolase involved in NAD metabolism
Bt4C1_21255	COG1534	Rna-binding protein
Bt4C1_21265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Bt4C1_21270	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Bt4C1_21285	COG1191	sigma factor activity
Bt4C1_21295	COG1595	DNA-templated transcription, initiation
Bt4C1_21305	COG0778	Nitroreductase
Bt4C1_21310	COG2357	RelA SpoT domain protein
Bt4C1_21320	COG1785	Belongs to the alkaline phosphatase family
Bt4C1_21330	COG2267	carboxylic ester hydrolase activity
Bt4C1_21365	COG1404	Belongs to the peptidase S8 family
Bt4C1_21370	COG3186	Phenylalanine-4-hydroxylase
Bt4C1_21380	COG2514	catechol 2,3-dioxygenase activity
Bt4C1_21385	COG2259	Doxx family
Bt4C1_21425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Bt4C1_21435	COG1012	belongs to the aldehyde dehydrogenase family
Bt4C1_21435	COG1454	alcohol dehydrogenase
Bt4C1_21440	COG0626	cystathionine gamma-synthase activity
Bt4C1_21445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bt4C1_21470	COG0768	penicillin binding
Bt4C1_21505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Bt4C1_21535	COG0628	permease
Bt4C1_21555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Bt4C1_21570	COG1104	cysteine desulfurase activity
Bt4C1_21575	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_21580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Bt4C1_21590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Bt4C1_21620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Bt4C1_21630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Bt4C1_21630	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Bt4C1_21635	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bt4C1_21640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bt4C1_21640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bt4C1_21650	COG2244	polysaccharide biosynthetic process
Bt4C1_21655	COG2323	membrane
Bt4C1_21665	COG1862	Preprotein translocase
Bt4C1_21695	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Bt4C1_21725	COG0157	Belongs to the NadC ModD family
Bt4C1_21730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Bt4C1_21735	COG1104	cysteine desulfurase activity
Bt4C1_21740	COG1827	regulation of RNA biosynthetic process
Bt4C1_21745	COG2258	MOSC domain
Bt4C1_21755	COG0077	Prephenate dehydratase
Bt4C1_21760	COG0577	efflux transmembrane transporter activity
Bt4C1_21765	COG0577	efflux transmembrane transporter activity
Bt4C1_21770	COG1136	(ABC) transporter
Bt4C1_21775	COG5002	protein histidine kinase activity
Bt4C1_21780	COG0745	RESPONSE REGULATOR receiver
Bt4C1_21790	COG3290	protein histidine kinase activity
Bt4C1_21800	COG2868	ribosomal protein
Bt4C1_21810	COG1530	ribonuclease E activity
Bt4C1_21815	COG1994	Peptidase M50
Bt4C1_21820	COG0739	heme binding
Bt4C1_21825	COG2894	cell division
Bt4C1_21840	COG1792	Involved in formation and maintenance of cell shape
Bt4C1_21845	COG1077	Cell shape determining protein MreB Mrl
Bt4C1_21865	COG0285	dihydrofolate synthase activity
Bt4C1_21880	COG1388	LysM domain
Bt4C1_21890	COG0113	porphobilinogen synthase activity
Bt4C1_21895	COG1587	Uroporphyrinogen-III synthase
Bt4C1_21905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bt4C1_21915	COG1846	Transcriptional regulator
Bt4C1_21920	COG1764	response to oxidative stress
Bt4C1_21935	COG1067	ATP-dependent peptidase activity
Bt4C1_21935	COG0470	DNA polymerase III
Bt4C1_21960	COG2801	Transposase and inactivated derivatives
Bt4C1_22050	COG0622	Phosphoesterase
Bt4C1_22065	COG5401	PFAM Sporulation and spore germination
Bt4C1_22085	COG1309	transcriptional regulator
Bt4C1_22095	COG2197	response regulator
Bt4C1_22100	COG2233	PERMEase
Bt4C1_22105	COG0402	S-adenosylhomocysteine deaminase activity
Bt4C1_22110	COG1983	PspC domain protein
Bt4C1_22115	COG1396	sequence-specific DNA binding
Bt4C1_22120	COG0697	spore germination
Bt4C1_22130	COG1959	2 iron, 2 sulfur cluster binding
Bt4C1_22135	COG1668	transmembrane transport
Bt4C1_22140	COG4152	abc transporter atp-binding protein
Bt4C1_22145	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
Bt4C1_22150	COG1360	Flagellar Motor Protein
Bt4C1_22155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Bt4C1_22160	COG1876	peptidase activity
Bt4C1_22165	COG0824	Thioesterase
Bt4C1_22170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Bt4C1_22175	COG1053	succinate dehydrogenase
Bt4C1_22180	COG2009	succinate dehydrogenase
Bt4C1_22185	COG1719	4-vinyl reductase, 4VR
Bt4C1_22195	COG3118	belongs to the thioredoxin family
Bt4C1_22200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Bt4C1_22205	COG2086	electron transfer activity
Bt4C1_22210	COG1024	Enoyl-CoA hydratase
Bt4C1_22215	COG1309	transcriptional regulator
Bt4C1_22220	COG0318	PFAM AMP-dependent synthetase and ligase
Bt4C1_22245	COG2318	DinB family
Bt4C1_22260	COG1131	(ABC) transporter
Bt4C1_22265	COG2205	protein histidine kinase activity
Bt4C1_22270	COG0745	RESPONSE REGULATOR receiver
Bt4C1_22280	COG4895	conserved protein (DUF2196)
Bt4C1_22285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Bt4C1_22295	COG4509	Sortase family
Bt4C1_22300	COG1120	ATPase activity
Bt4C1_22315	COG5386	Cell surface protein
Bt4C1_22325	COG5386	Cell surface protein
Bt4C1_22330	COG1114	Component of the transport system for branched-chain amino acids
Bt4C1_22335	COG1187	pseudouridine synthase activity
Bt4C1_22345	COG1796	DNA polymerase
Bt4C1_22345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bt4C1_22350	COG1286	toxin biosynthetic process
Bt4C1_22375	COG0017	Asparaginyl-tRNA synthetase
Bt4C1_22390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bt4C1_22400	COG1418	mRNA catabolic process
Bt4C1_22415	COG2814	Major facilitator Superfamily
Bt4C1_22420	COG1566	PFAM secretion protein HlyD family protein
Bt4C1_22425	COG1309	transcriptional regulator
Bt4C1_22430	COG1363	Peptidase, m42
Bt4C1_22455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bt4C1_22470	COG1484	DNA-dependent DNA replication
Bt4C1_22475	COG3611	Membrane attachment protein
Bt4C1_22485	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Bt4C1_22490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bt4C1_22495	COG0237	dephospho-CoA kinase activity
Bt4C1_22500	COG1971	Probably functions as a manganese efflux pump
Bt4C1_22510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_22510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bt4C1_22515	COG5002	protein histidine kinase activity
Bt4C1_22520	COG0745	RESPONSE REGULATOR receiver
Bt4C1_22540	COG0538	isocitrate dehydrogenase activity
Bt4C1_22545	COG0372	Belongs to the citrate synthase family
Bt4C1_22555	COG0628	permease
Bt4C1_22560	COG3030	protein affecting phage T7 exclusion by the F plasmid
Bt4C1_22585	COG1725	Transcriptional regulator
Bt4C1_22595	COG0587	DNA-directed DNA polymerase activity
Bt4C1_22610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Bt4C1_22625	COG4109	DRTGG domain
Bt4C1_22640	COG0006	proline dipeptidase activity
Bt4C1_22675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_22680	COG0662	Cupin 2, conserved barrel domain protein
Bt4C1_22690	COG1028	Short-chain dehydrogenase reductase Sdr
Bt4C1_22695	COG0589	response to stress
Bt4C1_22735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_22760	COG0827	DNA restriction-modification system
Bt4C1_22765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Bt4C1_22770	COG3874	Sporulation protein YtfJ
Bt4C1_22785	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Bt4C1_22795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bt4C1_22810	COG1104	cysteine desulfurase activity
Bt4C1_22820	COG0583	DNA-binding transcription factor activity
Bt4C1_22825	COG0697	spore germination
Bt4C1_22830	COG1309	transcriptional regulator
Bt4C1_22835	COG1956	GAF domain-containing protein
Bt4C1_22840	COG0626	cystathionine gamma-synthase activity
Bt4C1_22875	COG1595	DNA-templated transcription, initiation
Bt4C1_22885	COG0110	maltose O-acetyltransferase activity
Bt4C1_22890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bt4C1_22895	COG0454	-acetyltransferase
Bt4C1_22900	COG0517	IMP dehydrogenase activity
Bt4C1_22905	COG0123	including yeast histone deacetylase and acetoin utilization protein
Bt4C1_22920	COG0745	RESPONSE REGULATOR receiver
Bt4C1_22925	COG5002	protein histidine kinase activity
Bt4C1_22930	COG0666	response to abiotic stimulus
Bt4C1_22965	COG1609	Transcriptional regulator
Bt4C1_22975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bt4C1_22975	COG1605	Chorismate mutase
Bt4C1_22980	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bt4C1_22980	COG1605	Chorismate mutase
Bt4C1_22985	COG4851	CamS sex pheromone cAM373 precursor
Bt4C1_22990	COG3118	belongs to the thioredoxin family
Bt4C1_23000	COG2309	aminopeptidase activity
Bt4C1_23015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_23020	COG0697	spore germination
Bt4C1_23025	COG0789	Transcriptional regulator
Bt4C1_23040	COG1674	ftsk spoiiie
Bt4C1_23055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bt4C1_23065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_23070	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Bt4C1_23075	COG1363	Peptidase, m42
Bt4C1_23085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_23100	COG0510	thiamine kinase activity
Bt4C1_23105	COG1523	belongs to the glycosyl hydrolase 13 family
Bt4C1_23115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bt4C1_23120	COG1349	DNA-binding transcription factor activity
Bt4C1_23125	COG1187	pseudouridine synthase activity
Bt4C1_23130	COG2244	polysaccharide biosynthetic process
Bt4C1_23135	COG2081	HI0933 family
Bt4C1_23140	COG2814	Major facilitator Superfamily
Bt4C1_23150	COG3832	glyoxalase III activity
Bt4C1_23170	COG1329	Transcriptional regulator
Bt4C1_23195	COG0314	molybdopterin synthase activity
Bt4C1_23200	COG1763	Mo-molybdopterin cofactor biosynthetic process
Bt4C1_23205	COG0303	'Molybdopterin
Bt4C1_23215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bt4C1_23220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Bt4C1_23240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bt4C1_23250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Bt4C1_23290	COG2814	Major facilitator Superfamily
Bt4C1_23295	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_23300	COG0490	domain, Protein
Bt4C1_23305	COG0582	viral genome integration into host DNA
Bt4C1_23315	COG1136	(ABC) transporter
Bt4C1_23335	COG1242	4 iron, 4 sulfur cluster binding
Bt4C1_23340	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Bt4C1_23345	COG1794	racemase activity, acting on amino acids and derivatives
Bt4C1_23360	COG2267	carboxylic ester hydrolase activity
Bt4C1_23365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Bt4C1_23370	COG0671	phosphoesterase, PA-phosphatase related
Bt4C1_23375	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_23465	COG5002	protein histidine kinase activity
Bt4C1_23470	COG3852	Histidine kinase
Bt4C1_23480	COG2267	carboxylic ester hydrolase activity
Bt4C1_23485	COG1368	sulfuric ester hydrolase activity
Bt4C1_23495	COG4895	conserved protein (DUF2196)
Bt4C1_23510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bt4C1_23515	COG1116	anion transmembrane transporter activity
Bt4C1_23520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bt4C1_23545	COG0494	nUDIX hydrolase
Bt4C1_23575	COG2076	Multidrug Resistance protein
Bt4C1_23580	COG2076	Multidrug Resistance protein
Bt4C1_23585	COG0789	Transcriptional regulator
Bt4C1_23600	COG0288	reversible hydration of carbon dioxide
Bt4C1_23610	COG1294	oxidase, subunit
Bt4C1_23630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_23655	COG1842	Phage shock protein A
Bt4C1_23680	COG3859	Proton-coupled thiamine transporter YuaJ
Bt4C1_23685	COG5002	protein histidine kinase activity
Bt4C1_23690	COG0745	RESPONSE REGULATOR receiver
Bt4C1_23720	COG1597	lipid kinase activity
Bt4C1_23765	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_23775	COG0577	efflux transmembrane transporter activity
Bt4C1_23780	COG1136	(ABC) transporter
Bt4C1_23785	COG2207	Transcriptional regulator
Bt4C1_23785	COG3708	Transcriptional regulator
Bt4C1_23795	COG1131	(ABC) transporter
Bt4C1_23800	COG5658	integral membrane protein
Bt4C1_23805	COG0640	Transcriptional regulator
Bt4C1_23815	COG0745	RESPONSE REGULATOR receiver
Bt4C1_23820	COG2205	protein histidine kinase activity
Bt4C1_23825	COG0577	efflux transmembrane transporter activity
Bt4C1_23830	COG0577	efflux transmembrane transporter activity
Bt4C1_23835	COG1136	(ABC) transporter
Bt4C1_23840	COG0577	efflux transmembrane transporter activity
Bt4C1_23875	COG3964	amidohydrolase
Bt4C1_23895	COG4948	Mandelate Racemase Muconate Lactonizing
Bt4C1_23905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Bt4C1_23910	COG0596	Alpha beta hydrolase
Bt4C1_23920	COG1169	isochorismate synthase
Bt4C1_23925	COG1575	Belongs to the MenA family. Type 1 subfamily
Bt4C1_23930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Bt4C1_23935	COG1278	Cold shock
Bt4C1_23960	COG0058	SHG alpha-glucan phosphorylase activity
Bt4C1_23970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Bt4C1_23990	COG0039	L-malate dehydrogenase activity
Bt4C1_23995	COG1309	transcriptional regulator
Bt4C1_24140	COG1285	pathogenesis
Bt4C1_24145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Bt4C1_24160	COG2155	Conserved Protein
Bt4C1_24165	COG1098	S1 RNA binding domain
Bt4C1_24170	COG0436	Aminotransferase
Bt4C1_24175	COG1522	sequence-specific DNA binding
Bt4C1_24180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bt4C1_24185	COG2267	carboxylic ester hydrolase activity
Bt4C1_24195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Bt4C1_24215	COG5018	Exonuclease
Bt4C1_24220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bt4C1_24235	COG0423	glycine-tRNA ligase activity
Bt4C1_24240	COG2050	protein possibly involved in aromatic compounds catabolism
Bt4C1_24250	COG1268	BioY protein
Bt4C1_24255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bt4C1_24260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bt4C1_24275	COG3584	3D domain protein
Bt4C1_24290	COG1252	NADH dehydrogenase
Bt4C1_24300	COG3708	Transcriptional regulator
Bt4C1_24315	COG1683	Conserved Protein
Bt4C1_24340	COG0316	Belongs to the HesB IscA family
Bt4C1_24355	COG1252	NADH dehydrogenase
Bt4C1_24365	COG2274	protein secretion by the type I secretion system
Bt4C1_24370	COG0390	transport system, permease component
Bt4C1_24375	COG2824	Alkylphosphonate utilization operon protein PhnA
Bt4C1_24425	COG4837	Protein of unknown function (DUF1462)
Bt4C1_24430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Bt4C1_24440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Bt4C1_24445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Bt4C1_24465	COG1358	cellular component organization or biogenesis
Bt4C1_24475	COG2249	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_24480	COG0647	UMP catabolic process
Bt4C1_24490	COG2445	Protein of unknown function DUF86
Bt4C1_24495	COG1494	fructose-1,6-bisphosphatase
Bt4C1_24510	COG4470	Protein conserved in bacteria
Bt4C1_24520	COG0789	Transcriptional regulator
Bt4C1_24525	COG4377	Putative membrane peptidase family (DUF2324)
Bt4C1_24550	COG0739	heme binding
Bt4C1_24560	COG3377	Domain of unknown function (DUF1805)
Bt4C1_24565	COG0737	Belongs to the 5'-nucleotidase family
Bt4C1_24570	COG0719	Fe-S assembly protein
Bt4C1_24575	COG0822	iron-sulfur transferase activity
Bt4C1_24580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Bt4C1_24585	COG0719	Fe-S assembly protein
Bt4C1_24590	COG0396	ATPase activity
Bt4C1_24595	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_24600	COG1464	Belongs to the NlpA lipoprotein family
Bt4C1_24605	COG2011	ABC-type metal ion transport system permease component
Bt4C1_24620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bt4C1_24625	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Bt4C1_24635	COG1393	Belongs to the ArsC family
Bt4C1_24670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bt4C1_24675	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_24680	COG0183	Belongs to the thiolase family
Bt4C1_24685	COG1024	Enoyl-CoA hydratase
Bt4C1_24685	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bt4C1_24695	COG1686	Belongs to the peptidase S11 family
Bt4C1_24710	COG0011	TIGRFAM Protein of
Bt4C1_24715	COG0840	transmembrane signaling receptor activity
Bt4C1_24730	COG2814	Major facilitator Superfamily
Bt4C1_24735	COG0531	amino acid
Bt4C1_24760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_24790	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_24800	COG1376	ErfK ybiS ycfS ynhG family protein
Bt4C1_24805	COG0745	RESPONSE REGULATOR receiver
Bt4C1_24810	COG5002	protein histidine kinase activity
Bt4C1_24840	COG0840	transmembrane signaling receptor activity
Bt4C1_24845	COG2151	metal-sulfur cluster biosynthetic enzyme
Bt4C1_24850	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_24870	COG0586	Pfam SNARE associated Golgi protein
Bt4C1_24875	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_24880	COG0490	domain, Protein
Bt4C1_24885	COG1115	amino acid carrier protein
Bt4C1_24890	COG0783	Belongs to the Dps family
Bt4C1_24905	COG1611	Belongs to the LOG family
Bt4C1_24915	COG1528	Iron-storage protein
Bt4C1_24925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_24930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_24935	COG1115	amino acid carrier protein
Bt4C1_24940	COG1115	amino acid carrier protein
Bt4C1_24945	COG2910	NAD(P)H-binding
Bt4C1_24960	COG0656	L-ascorbic acid biosynthetic process
Bt4C1_24965	COG2814	Major facilitator Superfamily
Bt4C1_24970	COG1733	regulation of RNA biosynthetic process
Bt4C1_24980	COG1252	NADH dehydrogenase
Bt4C1_25035	COG0488	(ABC) transporter
Bt4C1_25040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bt4C1_25050	COG3223	Belongs to the PsiE family
Bt4C1_25060	COG1335	isochorismatase
Bt4C1_25065	COG1522	sequence-specific DNA binding
Bt4C1_25075	COG1522	sequence-specific DNA binding
Bt4C1_25080	COG0288	reversible hydration of carbon dioxide
Bt4C1_25085	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Bt4C1_25090	COG2233	PERMEase
Bt4C1_25145	COG0557	exoribonuclease II activity
Bt4C1_25150	COG1647	Serine aminopeptidase, S33
Bt4C1_25155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bt4C1_25160	COG1346	cytolysis
Bt4C1_25195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bt4C1_25210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Bt4C1_25235	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_25455	COG0582	viral genome integration into host DNA
Bt4C1_25530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Bt4C1_25550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bt4C1_25565	COG2323	membrane
Bt4C1_25575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bt4C1_25585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Bt4C1_25595	COG1051	belongs to the nudix hydrolase family
Bt4C1_25605	COG0492	ferredoxin-NADP+ reductase activity
Bt4C1_25610	COG0457	Tetratricopeptide repeat
Bt4C1_25615	COG0110	maltose O-acetyltransferase activity
Bt4C1_25635	COG1950	PFAM Membrane protein of
Bt4C1_25645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Bt4C1_25665	COG0789	Transcriptional regulator
Bt4C1_25685	COG0583	DNA-binding transcription factor activity
Bt4C1_25695	COG0655	NAD(P)H dehydrogenase (quinone) activity
Bt4C1_25700	COG0488	(ABC) transporter
Bt4C1_25710	COG1132	(ABC) transporter
Bt4C1_25715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bt4C1_25720	COG0793	Belongs to the peptidase S41A family
Bt4C1_25720	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_25725	COG2177	Part of the ABC transporter FtsEX involved in
Bt4C1_25730	COG2884	Cell division ATP-binding protein ftsE
Bt4C1_25740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Bt4C1_25750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Bt4C1_25755	COG1278	Cold shock
Bt4C1_25760	COG1040	competence protein
Bt4C1_25785	COG1388	LysM domain
Bt4C1_25785	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_25785	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_25790	COG4824	toxin secretion phage lysis holin
Bt4C1_26000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Bt4C1_26005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bt4C1_26010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Bt4C1_26015	COG0791	NLP P60 protein
Bt4C1_26020	COG1733	regulation of RNA biosynthetic process
Bt4C1_26025	COG1307	EDD domain protein, DegV family
Bt4C1_26030	COG1739	Uncharacterized protein family UPF0029
Bt4C1_26035	COG1316	TRANSCRIPTIONal
Bt4C1_26040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Bt4C1_26045	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Bt4C1_26050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Bt4C1_26060	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Bt4C1_26060	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Bt4C1_26080	COG1486	melibiose metabolic process
Bt4C1_26085	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bt4C1_26090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bt4C1_26100	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Bt4C1_26110	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bt4C1_26120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bt4C1_26125	COG1301	dicarboxylic acid transport
Bt4C1_26140	COG1511	domain protein
Bt4C1_26145	COG0583	DNA-binding transcription factor activity
Bt4C1_26160	COG1271	oxidase subunit
Bt4C1_26165	COG1294	oxidase, subunit
Bt4C1_26170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bt4C1_26180	COG1620	l-lactate permease
Bt4C1_26190	COG2389	metal-binding protein
Bt4C1_26200	COG1368	sulfuric ester hydrolase activity
Bt4C1_26210	COG0791	NLP P60 protein
Bt4C1_26210	COG1388	LysM domain
Bt4C1_26215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Bt4C1_26225	COG1215	transferase activity, transferring glycosyl groups
Bt4C1_26235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bt4C1_26240	COG1388	LysM domain
Bt4C1_26240	COG3584	3D domain protein
Bt4C1_26265	COG4715	Zinc finger, swim domain protein
Bt4C1_26270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bt4C1_26300	COG1191	sigma factor activity
Bt4C1_26310	COG0577	efflux transmembrane transporter activity
Bt4C1_26315	COG1136	(ABC) transporter
Bt4C1_26340	COG5002	protein histidine kinase activity
Bt4C1_26345	COG0745	RESPONSE REGULATOR receiver
Bt4C1_26365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Bt4C1_26370	COG1215	transferase activity, transferring glycosyl groups
Bt4C1_26395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bt4C1_26400	COG4464	protein tyrosine phosphatase activity
Bt4C1_26405	COG0489	protein tyrosine kinase activity
Bt4C1_26410	COG3944	biosynthesis protein
Bt4C1_26415	COG0489	protein tyrosine kinase activity
Bt4C1_26430	COG1609	Transcriptional regulator
Bt4C1_26440	COG0739	heme binding
Bt4C1_26455	COG3279	Response regulator of the LytR AlgR family
Bt4C1_26460	COG2385	sporulation resulting in formation of a cellular spore
Bt4C1_26465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Bt4C1_26475	COG4836	Membrane
Bt4C1_26480	COG1007	ATP synthesis coupled electron transport
Bt4C1_26485	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bt4C1_26490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Bt4C1_26500	COG0839	Belongs to the complex I subunit 6 family
Bt4C1_26520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bt4C1_26535	COG3300	MHYT domain
Bt4C1_26535	COG5001	Diguanylate cyclase
Bt4C1_26585	COG0356	it plays a direct role in the translocation of protons across the membrane
Bt4C1_26615	COG0698	ribose 5-phosphate isomerase
Bt4C1_26625	COG2190	(PTS) system
Bt4C1_26630	COG2259	Doxx family
Bt4C1_26635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Bt4C1_26650	COG0009	L-threonylcarbamoyladenylate synthase
Bt4C1_26670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Bt4C1_26685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Bt4C1_26690	COG1494	fructose-1,6-bisphosphatase
Bt4C1_26710	COG4821	SIS domain
Bt4C1_26730	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_26735	COG1960	acyl-CoA dehydrogenase activity
Bt4C1_26740	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bt4C1_26745	COG0183	Belongs to the thiolase family
Bt4C1_26750	COG2181	nitrate reductase activity
Bt4C1_26750	COG0247	lactate metabolic process
Bt4C1_26755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bt4C1_26765	COG5001	Diguanylate cyclase
Bt4C1_26765	COG3300	MHYT domain
Bt4C1_26780	COG3227	Zinc metalloprotease (Elastase)
Bt4C1_26785	COG2197	response regulator
Bt4C1_26790	COG4585	Histidine kinase
Bt4C1_26795	COG0842	Transport permease protein
Bt4C1_26800	COG1131	(ABC) transporter
Bt4C1_26805	COG0024	Methionine aminopeptidase
Bt4C1_26815	COG2234	aminopeptidase activity
Bt4C1_26835	COG1595	DNA-templated transcription, initiation
Bt4C1_26845	COG4506	Protein conserved in bacteria
Bt4C1_26850	COG1619	proteins homologs of microcin C7 resistance protein MccF
Bt4C1_26870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Bt4C1_26875	COG2814	Major facilitator Superfamily
Bt4C1_26880	COG0789	Transcriptional regulator
Bt4C1_26885	COG0584	glycerophosphoryl diester phosphodiesterase
Bt4C1_26890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bt4C1_26900	COG1994	Peptidase M50
Bt4C1_26910	COG1078	dGTPase activity
Bt4C1_26915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bt4C1_26920	COG1120	ATPase activity
Bt4C1_26925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_26930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bt4C1_26950	COG0280	phosphate acetyltransferase
Bt4C1_26965	COG3773	Cell wall hydrolase
Bt4C1_26975	COG2363	Small membrane protein
Bt4C1_26985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Bt4C1_26990	COG2233	PERMEase
Bt4C1_26995	COG0561	phosphatase activity
Bt4C1_27000	COG2814	Major facilitator Superfamily
Bt4C1_27010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Bt4C1_27015	COG1131	(ABC) transporter
Bt4C1_27020	COG2755	lipolytic protein G-D-S-L family
Bt4C1_27025	COG1609	Transcriptional regulator
Bt4C1_27035	COG0460	homoserine dehydrogenase
Bt4C1_27050	COG1011	Hydrolase
Bt4C1_27055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bt4C1_27065	COG2197	response regulator
Bt4C1_27070	COG4585	Histidine kinase
Bt4C1_27070	COG2203	Gaf domain
Bt4C1_27075	COG0351	phosphomethylpyrimidine kinase
Bt4C1_27080	COG3706	GGDEF domain
Bt4C1_27085	COG2879	small protein
Bt4C1_27090	COG1966	Carbon starvation protein
Bt4C1_27095	COG3279	Response regulator of the LytR AlgR family
Bt4C1_27100	COG0477	Major facilitator Superfamily
Bt4C1_27110	COG0438	transferase activity, transferring glycosyl groups
Bt4C1_27125	COG0840	transmembrane signaling receptor activity
Bt4C1_27135	COG1607	acyl-coa hydrolase
Bt4C1_27140	COG1216	Glycosyl transferase, family 2
Bt4C1_27155	COG1216	Glycosyl transferase, family 2
Bt4C1_27165	COG4485	Bacterial membrane protein, YfhO
Bt4C1_27170	COG0463	Glycosyl transferase, family 2
Bt4C1_27180	COG1309	transcriptional regulator
Bt4C1_27185	COG0488	(ABC) transporter
Bt4C1_27190	COG1309	transcriptional regulator
Bt4C1_27195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Bt4C1_27200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bt4C1_27200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bt4C1_27205	COG0628	permease
Bt4C1_27225	COG3275	phosphorelay sensor kinase activity
Bt4C1_27230	COG2814	Major facilitator Superfamily
Bt4C1_27235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bt4C1_27240	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Bt4C1_27265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Bt4C1_27270	COG1272	protein, Hemolysin III
Bt4C1_27290	COG1164	Oligoendopeptidase f
Bt4C1_27305	COG5002	protein histidine kinase activity
Bt4C1_27385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bt4C1_27390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Bt4C1_27395	COG4853	Protein conserved in bacteria
Bt4C1_27405	COG5002	protein histidine kinase activity
Bt4C1_27410	COG0745	RESPONSE REGULATOR receiver
Bt4C1_27440	COG0305	Participates in initiation and elongation during chromosome replication
Bt4C1_27450	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Bt4C1_27455	COG4241	membrane
Bt4C1_27465	COG0629	single-stranded DNA binding
Bt4C1_27475	COG0012	GTP binding
Bt4C1_27480	COG4481	Protein conserved in bacteria
Bt4C1_27485	COG0668	transmembrane transport
Bt4C1_27495	COG1475	DNA binding
Bt4C1_27500	COG1192	Involved in chromosome partitioning
Bt4C1_27525	COG1847	R3H domain protein
Bt4C1_27550	COG0592	DNA-directed DNA polymerase activity
Bt4C1_27555	COG2501	S4 domain
Bt4C1_27565	COG0187	DNA topoisomerase II activity
Bt4C1_27570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bt4C1_27660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bt4C1_27665	COG0583	DNA-binding transcription factor activity
Bt4C1_27680	COG4974	Belongs to the 'phage' integrase family
Bt4C1_27695	COG4166	transmembrane transport
Bt4C1_27705	COG2002	toxin-antitoxin pair type II binding
Bt4C1_27720	COG0776	regulation of translation
Bt4C1_27735	COG3344	reverse transcriptase
Bt4C1_27750	COG2814	Major facilitator Superfamily
Bt4C1_27755	COG1846	Transcriptional regulator
Bt4C1_27760	COG1846	Transcriptional regulator
Bt4C1_27765	COG2124	cytochrome p450
Bt4C1_27785	COG2311	Membrane
Bt4C1_27850	COG3344	reverse transcriptase
Bt4C1_27865	COG3344	reverse transcriptase
Bt4C1_28100	COG2169	Transcriptional regulator
Bt4C1_28110	COG0673	inositol 2-dehydrogenase activity
Bt4C1_28330	COG1923	regulation of RNA biosynthetic process
Bt4C1_28335	COG0457	Tetratricopeptide repeat
Bt4C1_28370	COG4974	Belongs to the 'phage' integrase family
Bt4C1_28395	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Bt4C1_28445	COG0640	Transcriptional regulator
Bt4C1_28475	COG3290	protein histidine kinase activity
Bt4C1_28480	COG4565	transcriptional regulatory protein
Bt4C1_28485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bt4C1_28530	COG0675	Transposase, IS605 OrfB family
Bt4C1_28540	COG0840	transmembrane signaling receptor activity
Bt4C1_28545	COG0490	domain, Protein
Bt4C1_28550	COG0475	glutathione-regulated potassium exporter activity
Bt4C1_28555	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bt4C1_28555	COG3409	Peptidoglycan-binding domain 1 protein
Bt4C1_28565	COG0840	transmembrane signaling receptor activity
Bt4C1_28585	COG4974	Belongs to the 'phage' integrase family
Bt4C1_28620	COG4824	toxin secretion phage lysis holin
Bt4C1_28645	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Bt4C1_28685	COG3344	reverse transcriptase
Bt4C1_28900	COG4166	transmembrane transport
Bt4C1_28935	COG0457	Tetratricopeptide repeat
Bt4C1_28965	COG0551	DNA topoisomerase type I activity
Bt4C1_28965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bt4C1_29090	COG0791	NLP P60 protein
Bt4C1_29090	COG0741	lytic transglycosylase activity
Bt4C1_29265	COG0457	Tetratricopeptide repeat
Bt4C1_29275	COG1923	regulation of RNA biosynthetic process
Bt4C1_29390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD