locus-tag	class	description
D3C60_00010	COG0592	DNA-directed DNA polymerase activity
D3C60_00015	COG2501	S4 domain
D3C60_00030	COG0187	DNA topoisomerase II activity
D3C60_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3C60_00070	COG0517	IMP dehydrogenase activity
D3C60_00070	COG0516	GMP reductase activity
D3C60_00075	COG1686	Belongs to the peptidase S11 family
D3C60_00095	COG1929	Belongs to the glycerate kinase type-1 family
D3C60_00105	COG1428	Deoxynucleoside kinase
D3C60_00110	COG1428	Deoxynucleoside kinase
D3C60_00115	COG1388	LysM domain
D3C60_00115	COG3858	chitin binding
D3C60_00120	COG1335	isochorismatase
D3C60_00125	COG0590	tRNA wobble adenosine to inosine editing
D3C60_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D3C60_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D3C60_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D3C60_00195	COG3853	Toxic anion resistance protein (TelA)
D3C60_00200	COG1982	Orn Lys Arg decarboxylase major
D3C60_00210	COG3870	Protein conserved in bacteria
D3C60_00215	COG1728	Protein conserved in bacteria
D3C60_00220	COG0470	DNA polymerase III
D3C60_00225	COG1774	PSP1 C-terminal conserved region
D3C60_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D3C60_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3C60_00250	COG2002	toxin-antitoxin pair type II binding
D3C60_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3C60_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3C60_00260	COG0084	hydrolase, TatD family'
D3C60_00265	COG3583	domain protein
D3C60_00265	COG3584	3D domain protein
D3C60_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3C60_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3C60_00285	COG4466	Protein conserved in bacteria
D3C60_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3C60_00305	COG0251	oxidation-reduction process
D3C60_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3C60_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3C60_00345	COG2002	toxin-antitoxin pair type II binding
D3C60_00350	COG2244	polysaccharide biosynthetic process
D3C60_00355	COG3956	TIGRFAM MazG family protein
D3C60_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D3C60_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D3C60_00380	COG1098	S1 RNA binding domain
D3C60_00395	COG2208	phosphoserine phosphatase activity
D3C60_00400	COG2304	oxidoreductase activity
D3C60_00405	COG0515	serine threonine protein kinase
D3C60_00410	COG0037	tRNA processing
D3C60_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D3C60_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3C60_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3C60_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3C60_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
D3C60_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3C60_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D3C60_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3C60_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3C60_00475	COG1396	sequence-specific DNA binding
D3C60_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3C60_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3C60_00565	COG4463	regulation of RNA biosynthetic process
D3C60_00570	COG3880	PFAM UvrB UvrC protein
D3C60_00580	COG0542	response to heat
D3C60_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D3C60_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D3C60_00595	COG4956	integral membrane protein (PIN domain superfamily)
D3C60_00615	COG1045	serine acetyltransferase
D3C60_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D3C60_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3C60_00635	COG3688	RNA-binding protein containing a PIN domain
D3C60_00640	COG1595	DNA-templated transcription, initiation
D3C60_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3C60_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3C60_00655	COG0250	Participates in transcription elongation, termination and antitermination
D3C60_00660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D3C60_00675	COG0222	ribosome binding
D3C60_00680	COG2813	Specifically methylates the guanine in position
D3C60_00695	COG1358	cellular component organization or biogenesis
D3C60_00720	COG0596	Alpha beta hydrolase
D3C60_00725	COG0051	transcription antitermination factor activity, RNA binding
D3C60_00740	COG0089	rRNA binding
D3C60_00750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D3C60_00755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D3C60_00765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D3C60_00770	COG0255	Belongs to the universal ribosomal protein uL29 family
D3C60_00820	COG1841	ribosomal large subunit assembly
D3C60_00830	COG0201	protein transport
D3C60_00840	COG0024	Methionine aminopeptidase
D3C60_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D3C60_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D3C60_00880	COG1122	ATPase activity
D3C60_00885	COG1122	ATPase activity
D3C60_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3C60_00910	COG2226	methyltransferase
D3C60_00915	COG2318	DinB family
D3C60_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3C60_00930	COG0489	protein tyrosine kinase activity
D3C60_00940	COG2194	sulfuric ester hydrolase activity
D3C60_00945	COG0726	polysaccharide deacetylase
D3C60_01005	COG0738	Major facilitator superfamily
D3C60_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3C60_01025	COG0659	secondary active sulfate transmembrane transporter activity
D3C60_01030	COG0385	Bile acid
D3C60_01035	COG2819	hydrolase of the alpha beta superfamily
D3C60_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3C60_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3C60_01055	COG2207	Transcriptional regulator
D3C60_01060	COG3876	Protein conserved in bacteria
D3C60_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
D3C60_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3C60_01075	COG1263	PTS System
D3C60_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3C60_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3C60_01090	COG1683	Conserved Protein
D3C60_01120	COG1595	DNA-templated transcription, initiation
D3C60_01125	COG5662	AntiSigma factor
D3C60_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D3C60_01135	COG4856	YbbR-like protein
D3C60_01160	COG0515	serine threonine protein kinase
D3C60_01165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3C60_01175	COG1346	cytolysis
D3C60_01180	COG1380	Effector of murein hydrolase LrgA
D3C60_01185	COG1846	Transcriptional regulator
D3C60_01190	COG1113	amino acid transport
D3C60_01195	COG1011	Hydrolase
D3C60_01200	COG4585	Histidine kinase
D3C60_01205	COG2197	response regulator
D3C60_01210	COG1131	(ABC) transporter
D3C60_01250	COG0531	amino acid
D3C60_01255	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D3C60_01270	COG0584	glycerophosphoryl diester phosphodiesterase
D3C60_01275	COG2271	Major facilitator Superfamily
D3C60_01290	COG2368	4-hydroxyphenylacetate
D3C60_01300	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_01315	COG0371	Dehydrogenase
D3C60_01325	COG1183	phosphatidylcholine synthase activity
D3C60_01330	COG0586	Pfam SNARE associated Golgi protein
D3C60_01335	COG0688	phosphatidylethanolamine metabolic process
D3C60_01350	COG1301	dicarboxylic acid transport
D3C60_01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3C60_01360	COG0833	amino acid
D3C60_01365	COG2040	homocysteine
D3C60_01370	COG1115	amino acid carrier protein
D3C60_01375	COG2066	Belongs to the glutaminase family
D3C60_01380	COG4191	Histidine kinase
D3C60_01385	COG0784	Response regulator, receiver
D3C60_01400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3C60_01405	COG0778	Nitroreductase
D3C60_01410	COG0346	lactoylglutathione lyase activity
D3C60_01415	COG2259	Doxx family
D3C60_01420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_01435	COG3773	Cell wall hydrolase
D3C60_01445	COG3540	Alkaline phosphatase
D3C60_01450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3C60_01455	COG0805	protein transport
D3C60_01465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3C60_01470	COG0477	Major facilitator Superfamily
D3C60_01475	COG1309	transcriptional regulator
D3C60_01480	COG0252	asparaginase activity
D3C60_01485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D3C60_01490	COG1405	negative regulation of cell septum assembly
D3C60_01490	COG3012	SEC-C Motif Domain Protein
D3C60_01495	COG0667	Aldo Keto reductase
D3C60_01505	COG1595	DNA-templated transcription, initiation
D3C60_01510	COG1595	DNA-templated transcription, initiation
D3C60_01515	COG1876	peptidase activity
D3C60_01520	COG0457	Tetratricopeptide repeat
D3C60_01525	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_01530	COG0366	Alpha amylase catalytic
D3C60_01535	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3C60_01540	COG1121	(ABC) transporter
D3C60_01545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3C60_01550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3C60_01555	COG2310	stress, protein
D3C60_01560	COG2310	stress, protein
D3C60_01565	COG2310	stress, protein
D3C60_01570	COG0861	Integral membrane protein TerC family
D3C60_01580	COG3853	Toxic anion resistance protein (TelA)
D3C60_01585	COG0477	Major facilitator Superfamily
D3C60_01590	COG0517	IMP dehydrogenase activity
D3C60_01590	COG4175	Glycine betaine
D3C60_01595	COG4176	ABC-type proline glycine betaine transport system permease component
D3C60_01600	COG2113	Glycine betaine
D3C60_01605	COG1473	amidohydrolase
D3C60_01610	COG1288	antiporter activity
D3C60_01620	COG0366	Alpha amylase catalytic
D3C60_01630	COG2814	Major facilitator Superfamily
D3C60_01635	COG1846	Transcriptional regulator
D3C60_01640	COG1280	lysine exporter protein (LysE YggA)
D3C60_01645	COG3403	YqcI/YcgG family
D3C60_01650	COG1113	amino acid transport
D3C60_01655	COG3665	Urea carboxylase-associated protein
D3C60_01670	COG1082	Xylose isomerase domain protein TIM barrel
D3C60_01675	COG2271	Major facilitator Superfamily
D3C60_01680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D3C60_01685	COG3458	cephalosporin-C deacetylase activity
D3C60_01690	COG3541	Predicted nucleotidyltransferase
D3C60_01695	COG0506	proline dehydrogenase activity
D3C60_01700	COG1012	belongs to the aldehyde dehydrogenase family
D3C60_01705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3C60_01710	COG2508	Transcriptional regulator
D3C60_01720	COG1587	Uroporphyrinogen-III synthase
D3C60_01720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3C60_01725	COG2146	nitrite reductase [NAD(P)H] activity
D3C60_01730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3C60_01735	COG0243	molybdopterin cofactor binding
D3C60_01740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3C60_01745	COG2223	nitrite transmembrane transporter activity
D3C60_01750	COG0523	cobalamin synthesis protein
D3C60_01755	COG1063	alcohol dehydrogenase
D3C60_01760	COG1714	RDD family
D3C60_01770	COG2723	6-phospho-beta-galactosidase activity
D3C60_01780	COG3209	COG3209 Rhs family protein
D3C60_01785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D3C60_01790	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D3C60_01795	COG1733	regulation of RNA biosynthetic process
D3C60_01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_01820	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D3C60_01835	COG0697	spore germination
D3C60_01840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3C60_01850	COG2364	Membrane
D3C60_01855	COG1126	abc transporter atp-binding protein
D3C60_01860	COG0765	amino acid transport
D3C60_01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3C60_01870	COG0583	DNA-binding transcription factor activity
D3C60_01875	COG0163	prenyltransferase activity
D3C60_01880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D3C60_01895	COG3104	oligopeptide transport
D3C60_01900	COG5434	Belongs to the glycosyl hydrolase 28 family
D3C60_01910	COG0697	spore germination
D3C60_01920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D3C60_01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3C60_01940	COG0765	amino acid transport
D3C60_01945	COG1126	abc transporter atp-binding protein
D3C60_01955	COG2079	MmgE PrpD family protein
D3C60_01960	COG1136	(ABC) transporter
D3C60_01965	COG0577	efflux transmembrane transporter activity
D3C60_01970	COG0745	RESPONSE REGULATOR receiver
D3C60_01975	COG5002	protein histidine kinase activity
D3C60_01975	COG3850	Histidine kinase
D3C60_01980	COG0457	Tetratricopeptide repeat
D3C60_01995	COG0527	aspartate kinase activity
D3C60_02000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_02005	COG4605	iron ion homeostasis
D3C60_02010	COG4604	ABC transporter, ATP-binding protein
D3C60_02015	COG4607	ABC-type enterochelin transport system periplasmic component
D3C60_02020	COG2814	Major facilitator Superfamily
D3C60_02025	COG1309	transcriptional regulator
D3C60_02030	COG0778	Nitroreductase
D3C60_02035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3C60_02040	COG0640	Transcriptional regulator
D3C60_02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3C60_02050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3C60_02055	COG1012	belongs to the aldehyde dehydrogenase family
D3C60_02060	COG4975	Glucose uptake
D3C60_02065	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_02070	COG4549	nuclear export factor GLE1
D3C60_02075	COG1276	copper resistance
D3C60_02075	COG2372	response to copper ion
D3C60_02080	COG1349	DNA-binding transcription factor activity
D3C60_02090	COG2213	PTS system mannitol-specific
D3C60_02095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3C60_02105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3C60_02115	COG0561	phosphatase activity
D3C60_02125	COG1914	H( )-stimulated, divalent metal cation uptake system
D3C60_02135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D3C60_02140	COG1984	allophanate hydrolase subunit 2
D3C60_02145	COG1414	Transcriptional regulator
D3C60_02150	COG2755	lipolytic protein G-D-S-L family
D3C60_02160	COG2329	Antibiotic biosynthesis monooxygenase
D3C60_02165	COG0768	penicillin binding
D3C60_02170	COG4989	oxidoreductase activity
D3C60_02175	COG3711	transcriptional antiterminator
D3C60_02180	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_02185	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_02190	COG1917	Cupin 2, conserved barrel domain protein
D3C60_02195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3C60_02200	COG3871	stress protein (general stress protein 26)
D3C60_02215	COG2814	Major facilitator Superfamily
D3C60_02220	COG1522	sequence-specific DNA binding
D3C60_02225	COG0551	DNA topoisomerase type I activity
D3C60_02225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3C60_02230	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D3C60_02235	COG3706	GGDEF domain
D3C60_02240	COG5298	Protein conserved in bacteria
D3C60_02245	COG1215	transferase activity, transferring glycosyl groups
D3C60_02255	COG0531	amino acid
D3C60_02260	COG0494	nUDIX hydrolase
D3C60_02265	COG0028	Belongs to the TPP enzyme family
D3C60_02290	COG1794	racemase activity, acting on amino acids and derivatives
D3C60_02325	COG1914	H( )-stimulated, divalent metal cation uptake system
D3C60_02340	COG4876	unkown
D3C60_02350	COG2076	Multidrug Resistance protein
D3C60_02355	COG2217	Heavy metal translocating P-type atpase
D3C60_02360	COG3729	General stress protein
D3C60_02365	COG0662	Cupin 2, conserved barrel domain protein
D3C60_02370	COG2329	Antibiotic biosynthesis monooxygenase
D3C60_02375	COG3546	catalase activity
D3C60_02380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D3C60_02385	COG3290	protein histidine kinase activity
D3C60_02390	COG4565	transcriptional regulatory protein
D3C60_02395	COG1301	dicarboxylic acid transport
D3C60_02400	COG0628	permease
D3C60_02405	COG1131	(ABC) transporter
D3C60_02410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3C60_02420	COG1960	acyl-CoA dehydrogenase activity
D3C60_02435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3C60_02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_02450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D3C60_02455	COG0513	Belongs to the DEAD box helicase family
D3C60_02460	COG3402	PFAM membrane-flanked domain
D3C60_02465	COG3428	Bacterial PH domain
D3C60_02470	COG0705	Rhomboid family
D3C60_02480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D3C60_02485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3C60_02490	COG0864	Transcriptional regulator
D3C60_02495	COG2337	Toxic component of a toxin-antitoxin (TA) module
D3C60_02500	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_02505	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_02510	COG2172	sigma factor antagonist activity
D3C60_02515	COG2208	phosphoserine phosphatase activity
D3C60_02520	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_02530	COG1191	sigma factor activity
D3C60_02535	COG2208	phosphoserine phosphatase activity
D3C60_02540	COG2183	response to ionizing radiation
D3C60_02605	COG1959	2 iron, 2 sulfur cluster binding
D3C60_02610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3C60_02615	COG1090	epimerase
D3C60_02620	COG0457	Tetratricopeptide repeat
D3C60_02625	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3C60_02640	COG0477	Major facilitator Superfamily
D3C60_02645	COG1846	Transcriptional regulator
D3C60_02655	COG2030	dehydratase
D3C60_02670	COG1959	2 iron, 2 sulfur cluster binding
D3C60_02675	COG2910	NAD(P)H-binding
D3C60_02680	COG1309	transcriptional regulator
D3C60_02685	COG0300	oxidoreductase activity
D3C60_02695	COG3239	Fatty acid desaturase
D3C60_02705	COG1278	Cold shock
D3C60_02710	COG1329	Transcriptional regulator
D3C60_02730	COG1846	Transcriptional regulator
D3C60_02730	COG0456	acetyltransferase
D3C60_02735	COG2271	Major facilitator Superfamily
D3C60_02740	COG3621	Patatin-like phospholipase
D3C60_02750	COG0662	Cupin 2, conserved barrel domain protein
D3C60_02765	COG0277	FAD linked oxidase domain protein
D3C60_02790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3C60_02825	COG0351	phosphomethylpyrimidine kinase
D3C60_02840	COG1064	alcohol dehydrogenase
D3C60_02845	COG0789	Transcriptional regulator
D3C60_02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3C60_02870	COG2814	Major facilitator Superfamily
D3C60_02875	COG1309	transcriptional regulator
D3C60_02880	COG0697	spore germination
D3C60_02885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3C60_02890	COG5577	PFAM Coat F domain
D3C60_02900	COG1063	alcohol dehydrogenase
D3C60_02905	COG5577	PFAM Coat F domain
D3C60_02915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D3C60_02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3C60_02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3C60_02940	COG2814	Major facilitator Superfamily
D3C60_02945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3C60_02955	COG0730	response to heat
D3C60_02960	COG0456	acetyltransferase
D3C60_02965	COG4978	Transcriptional regulator
D3C60_02965	COG0789	Transcriptional regulator
D3C60_02970	COG0697	spore germination
D3C60_02975	COG1051	belongs to the nudix hydrolase family
D3C60_02980	COG2226	methyltransferase
D3C60_02985	COG0473	3-isopropylmalate dehydrogenase activity
D3C60_02990	COG1802	Transcriptional regulator
D3C60_02995	COG1819	glycosyl
D3C60_03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3C60_03015	COG1388	LysM domain
D3C60_03020	COG2814	Major facilitator Superfamily
D3C60_03025	COG2188	Transcriptional regulator
D3C60_03030	COG2186	Transcriptional regulator
D3C60_03035	COG2807	transmembrane transport
D3C60_03040	COG2076	Multidrug Resistance protein
D3C60_03045	COG2076	Multidrug Resistance protein
D3C60_03050	COG1309	transcriptional regulator
D3C60_03055	COG0531	amino acid
D3C60_03065	COG3832	glyoxalase III activity
D3C60_03070	COG0604	alcohol dehydrogenase
D3C60_03075	COG2814	Major facilitator Superfamily
D3C60_03115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D3C60_03120	COG0802	atpase or kinase
D3C60_03125	COG1214	PFAM Peptidase M22, glycoprotease
D3C60_03130	COG0456	acetyltransferase
D3C60_03135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D3C60_03140	COG0488	(ABC) transporter
D3C60_03155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3C60_03160	COG0805	protein transport
D3C60_03170	COG1266	CAAX protease self-immunity
D3C60_03175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D3C60_03210	COG0457	Tetratricopeptide repeat
D3C60_03215	COG1063	alcohol dehydrogenase
D3C60_03220	COG2211	Major facilitator Superfamily
D3C60_03225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3C60_03235	COG1842	Phage shock protein A
D3C60_03240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3C60_03245	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D3C60_03250	COG4260	virion core protein, lumpy skin disease virus
D3C60_03255	COG2755	lipolytic protein G-D-S-L family
D3C60_03255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D3C60_03265	COG1595	DNA-templated transcription, initiation
D3C60_03270	COG1063	alcohol dehydrogenase
D3C60_03275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3C60_03280	COG0823	Involved in the tonB-independent uptake of proteins
D3C60_03290	COG2132	Multicopper oxidase
D3C60_03295	COG1113	amino acid transport
D3C60_03300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3C60_03305	COG0714	Associated with various cellular activities
D3C60_03310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D3C60_03315	COG1305	Transglutaminase-like
D3C60_03340	COG2252	PERMEase
D3C60_03345	COG3064	Membrane
D3C60_03365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D3C60_03370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D3C60_03375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3C60_03380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3C60_03385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3C60_03400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D3C60_03410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D3C60_03415	COG0138	bifunctional purine biosynthesis protein purh
D3C60_03420	COG0151	Belongs to the GarS family
D3C60_03430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D3C60_03435	COG1470	cell adhesion involved in biofilm formation
D3C60_03440	COG4496	protein, YerC YecD
D3C60_03445	COG0069	glutamate synthase activity
D3C60_03460	COG0210	DNA helicase
D3C60_03470	COG4851	CamS sex pheromone cAM373 precursor
D3C60_03475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3C60_03480	COG1285	pathogenesis
D3C60_03485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3C60_03505	COG1309	transcriptional regulator
D3C60_03510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3C60_03515	COG1597	lipid kinase activity
D3C60_03520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3C60_03525	COG1106	Psort location Cytoplasmic, score
D3C60_03560	COG5444	nuclease activity
D3C60_03590	COG3546	catalase activity
D3C60_03595	COG0454	-acetyltransferase
D3C60_03605	COG2323	membrane
D3C60_03610	COG2329	Antibiotic biosynthesis monooxygenase
D3C60_03615	COG0346	lactoylglutathione lyase activity
D3C60_03625	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_03630	COG5583	Uncharacterized small protein (DUF2292)
D3C60_03635	COG0196	riboflavin kinase activity
D3C60_03640	COG0670	Belongs to the BI1 family
D3C60_03645	COG1846	Transcriptional regulator
D3C60_03650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3C60_03660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3C60_03660	COG2124	cytochrome p450
D3C60_03665	COG1368	sulfuric ester hydrolase activity
D3C60_03670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D3C60_03675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_03680	COG1442	glycosyl transferase family 8
D3C60_03685	COG1216	Glycosyl transferase, family 2
D3C60_03690	COG1442	glycosyl transferase family 8
D3C60_03695	COG2223	nitrite transmembrane transporter activity
D3C60_03700	COG0531	amino acid
D3C60_03705	COG1012	belongs to the aldehyde dehydrogenase family
D3C60_03710	COG0840	transmembrane signaling receptor activity
D3C60_03715	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_03720	COG0463	Glycosyl transferase, family 2
D3C60_03720	COG0457	Tetratricopeptide repeat
D3C60_03725	COG0488	(ABC) transporter
D3C60_03730	COG0789	Transcriptional regulator
D3C60_03735	COG2814	Major facilitator Superfamily
D3C60_03740	COG0488	(ABC) transporter
D3C60_03745	COG0513	Belongs to the DEAD box helicase family
D3C60_03750	COG0456	acetyltransferase
D3C60_03755	COG2130	NADP-dependent
D3C60_03770	COG3866	Pectate lyase
D3C60_03775	COG0471	metal ion transport
D3C60_03800	COG3290	protein histidine kinase activity
D3C60_03805	COG4565	transcriptional regulatory protein
D3C60_03810	COG3181	Tripartite tricarboxylate transporter family receptor
D3C60_03815	COG2851	Citrate transporter
D3C60_03820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3C60_03825	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D3C60_03835	COG2258	MOSC domain
D3C60_03855	COG0024	Methionine aminopeptidase
D3C60_03860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3C60_03860	COG1263	PTS System
D3C60_03870	COG1368	sulfuric ester hydrolase activity
D3C60_03880	COG0071	Belongs to the small heat shock protein (HSP20) family
D3C60_03895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3C60_03895	COG1263	PTS System
D3C60_03900	COG0366	Alpha amylase catalytic
D3C60_03905	COG2188	Transcriptional regulator
D3C60_03910	COG0778	Nitroreductase
D3C60_03925	COG0737	Belongs to the 5'-nucleotidase family
D3C60_03930	COG0693	protein deglycase activity
D3C60_03935	COG1609	Transcriptional regulator
D3C60_03940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3C60_03950	COG2814	Major facilitator Superfamily
D3C60_03960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3C60_03965	COG4980	gas vesicle protein
D3C60_03970	COG1295	ribonuclease BN
D3C60_03975	COG0477	Major facilitator Superfamily
D3C60_03980	COG0387	Pfam Sodium calcium exchanger
D3C60_03990	COG0668	transmembrane transport
D3C60_03995	COG0535	radical SAM domain protein
D3C60_04005	COG0726	polysaccharide deacetylase
D3C60_04010	COG2084	Dehydrogenase
D3C60_04020	COG0598	Magnesium transport protein CorA
D3C60_04025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D3C60_04030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3C60_04040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3C60_04050	COG4637	Psort location Cytoplasmic, score
D3C60_04055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3C60_04060	COG0022	dehydrogenase e1 component
D3C60_04065	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3C60_04070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3C60_04075	COG3284	Transcriptional regulator
D3C60_04085	COG1486	melibiose metabolic process
D3C60_04090	COG1737	Transcriptional regulator
D3C60_04095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3C60_04095	COG1263	PTS System
D3C60_04100	COG1132	(ABC) transporter
D3C60_04105	COG1132	(ABC) transporter
D3C60_04110	COG2259	Doxx family
D3C60_04115	COG2514	catechol 2,3-dioxygenase activity
D3C60_04130	COG1695	Transcriptional regulator
D3C60_04135	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3C60_04140	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D3C60_04145	COG0574	Belongs to the PEP-utilizing enzyme family
D3C60_04145	COG3848	Pyruvate phosphate dikinase
D3C60_04150	COG2732	(Barnase) inhibitor
D3C60_04155	COG2318	DinB family
D3C60_04160	COG2814	Major facilitator Superfamily
D3C60_04165	COG1846	Transcriptional regulator
D3C60_04170	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D3C60_04170	COG0392	lysyltransferase activity
D3C60_04175	COG0384	phenazine biosynthesis protein PhzF
D3C60_04180	COG0778	Nitroreductase
D3C60_04195	COG1090	epimerase
D3C60_04210	COG2814	Major facilitator Superfamily
D3C60_04220	COG3591	Belongs to the peptidase S1B family
D3C60_04235	COG3103	Sh3 type 3 domain protein
D3C60_04240	COG5658	integral membrane protein
D3C60_04245	COG0596	Alpha beta hydrolase
D3C60_04250	COG0463	Glycosyl transferase, family 2
D3C60_04255	COG4485	Bacterial membrane protein, YfhO
D3C60_04260	COG1988	membrane-bound metal-dependent
D3C60_04265	COG1194	a g-specific adenine glycosylase
D3C60_04275	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_04295	COG1132	(ABC) transporter
D3C60_04300	COG4129	membrane
D3C60_04310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3C60_04315	COG0735	belongs to the Fur family
D3C60_04425	COG1757	Na H antiporter
D3C60_04430	COG3340	Belongs to the peptidase S51 family
D3C60_04440	COG0277	FAD linked oxidase domain protein
D3C60_04450	COG0747	negative chemotaxis
D3C60_04455	COG0601	transmembrane transport
D3C60_04460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3C60_04465	COG0444	Belongs to the ABC transporter superfamily
D3C60_04470	COG4608	Belongs to the ABC transporter superfamily
D3C60_04475	COG0753	catalase activity
D3C60_04485	COG1116	anion transmembrane transporter activity
D3C60_04490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3C60_04495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3C60_04515	COG1476	TRANSCRIPTIONal
D3C60_04525	COG3382	B3 4 domain protein
D3C60_04530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3C60_04540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D3C60_04545	COG0789	Transcriptional regulator
D3C60_04550	COG1664	Polymer-forming cytoskeletal
D3C60_04555	COG1664	Polymer-forming cytoskeletal
D3C60_04565	COG2766	serine protein kinase
D3C60_04580	COG1846	Transcriptional regulator
D3C60_04585	COG1566	PFAM secretion protein HlyD family protein
D3C60_04590	COG2814	Major facilitator Superfamily
D3C60_04595	COG0655	NAD(P)H dehydrogenase (quinone) activity
D3C60_04610	COG1725	Transcriptional regulator
D3C60_04615	COG1131	(ABC) transporter
D3C60_04620	COG1131	(ABC) transporter
D3C60_04625	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3C60_04630	COG1278	Cold shock
D3C60_04640	COG1464	Belongs to the NlpA lipoprotein family
D3C60_04645	COG3706	GGDEF domain
D3C60_04650	COG1823	symporter activity
D3C60_04670	COG5577	PFAM Coat F domain
D3C60_04675	COG4085	toxin activity
D3C60_04675	COG1525	nuclease
D3C60_04675	COG0737	Belongs to the 5'-nucleotidase family
D3C60_04680	COG3764	Sortase (surface protein transpeptidase)
D3C60_04685	COG0564	pseudouridine synthase activity
D3C60_04695	COG0517	IMP dehydrogenase activity
D3C60_04700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3C60_04705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3C60_04705	COG3153	acetyltransferase
D3C60_04715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3C60_04720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D3C60_04725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D3C60_04735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D3C60_04740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3C60_04745	COG4585	Histidine kinase
D3C60_04745	COG2203	Gaf domain
D3C60_04750	COG2197	response regulator
D3C60_04755	COG0431	NADPH-dependent FMN reductase
D3C60_04770	COG1388	LysM domain
D3C60_04770	COG0791	NLP P60 protein
D3C60_04775	COG1959	2 iron, 2 sulfur cluster binding
D3C60_04780	COG0668	transmembrane transport
D3C60_04785	COG2719	SpoVR family
D3C60_04790	COG1785	Belongs to the alkaline phosphatase family
D3C60_04795	COG0791	NLP P60 protein
D3C60_04795	COG1388	LysM domain
D3C60_04800	COG0583	DNA-binding transcription factor activity
D3C60_04805	COG0372	Belongs to the citrate synthase family
D3C60_04810	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_04815	COG0531	amino acid
D3C60_04820	COG0733	neurotransmitter:sodium symporter activity
D3C60_04835	COG1595	DNA-templated transcription, initiation
D3C60_04840	COG0204	Acyl-transferase
D3C60_04845	COG1253	flavin adenine dinucleotide binding
D3C60_04850	COG0789	Transcriptional regulator
D3C60_04855	COG0436	Aminotransferase
D3C60_04860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3C60_04865	COG1253	flavin adenine dinucleotide binding
D3C60_04870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3C60_04875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3C60_04880	COG0584	glycerophosphoryl diester phosphodiesterase
D3C60_04890	COG0668	transmembrane transport
D3C60_04895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D3C60_04900	COG0726	polysaccharide deacetylase
D3C60_04905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3C60_04910	COG3226	Transcriptional regulator
D3C60_04920	COG0589	response to stress
D3C60_04925	COG1132	(ABC) transporter
D3C60_04930	COG1132	(ABC) transporter
D3C60_04935	COG0702	epimerase
D3C60_04955	COG0189	ligase activity
D3C60_04960	COG0189	ligase activity
D3C60_04975	COG4335	DNA alkylation repair
D3C60_04980	COG0561	phosphatase activity
D3C60_04985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3C60_04995	COG0475	glutathione-regulated potassium exporter activity
D3C60_05000	COG0490	domain, Protein
D3C60_05010	COG1024	Enoyl-CoA hydratase
D3C60_05020	COG4152	abc transporter atp-binding protein
D3C60_05025	COG1668	transmembrane transport
D3C60_05030	COG0420	3'-5' exonuclease activity
D3C60_05035	COG4717	serine-type aminopeptidase activity
D3C60_05050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3C60_05090	COG4980	gas vesicle protein
D3C60_05105	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D3C60_05110	COG0537	adenosine 5'-monophosphoramidase activity
D3C60_05115	COG1131	(ABC) transporter
D3C60_05120	COG4473	ABC transporter
D3C60_05130	COG1473	amidohydrolase
D3C60_05135	COG3069	C4-dicarboxylate transmembrane transporter activity
D3C60_05140	COG2329	Antibiotic biosynthesis monooxygenase
D3C60_05145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3C60_05165	COG1309	transcriptional regulator
D3C60_05170	COG1511	domain protein
D3C60_05175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3C60_05185	COG1363	Peptidase, m42
D3C60_05190	COG1301	dicarboxylic acid transport
D3C60_05200	COG1234	tRNA 3'-trailer cleavage
D3C60_05205	COG0095	Lipoate-protein ligase
D3C60_05210	COG0702	epimerase
D3C60_05215	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_05225	COG0501	Belongs to the peptidase M48B family
D3C60_05230	COG1404	Belongs to the peptidase S8 family
D3C60_05240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D3C60_05245	COG0406	alpha-ribazole phosphatase activity
D3C60_05250	COG0183	Belongs to the thiolase family
D3C60_05255	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_05260	COG1268	BioY protein
D3C60_05265	COG0840	transmembrane signaling receptor activity
D3C60_05270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3C60_05270	COG0723	plastoquinol--plastocyanin reductase activity
D3C60_05275	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_05285	COG4903	ComK protein
D3C60_05295	COG5646	InterPro IPR014922
D3C60_05320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3C60_05335	COG0398	Pfam SNARE associated Golgi protein
D3C60_05340	COG0681	Belongs to the peptidase S26 family
D3C60_05345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3C60_05350	COG1846	Transcriptional regulator
D3C60_05355	COG3180	Ammonia monooxygenase
D3C60_05360	COG2814	Major facilitator Superfamily
D3C60_05370	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D3C60_05375	COG2323	membrane
D3C60_05390	COG0420	3'-5' exonuclease activity
D3C60_05395	COG0419	ATPase involved in DNA repair
D3C60_05400	COG1403	HNH endonuclease
D3C60_05440	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3C60_05460	COG0367	asparagine synthase
D3C60_05465	COG1562	ergosterol biosynthetic process
D3C60_05470	COG0534	Mate efflux family protein
D3C60_05475	COG2207	Transcriptional regulator
D3C60_05475	COG1917	Cupin 2, conserved barrel domain protein
D3C60_05480	COG2318	DinB family
D3C60_05490	COG1357	PFAM Pentapeptide repeats (8 copies)
D3C60_05495	COG2153	protein acetylation
D3C60_05500	COG0646	methionine synthase
D3C60_05500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D3C60_05510	COG2996	Protein conserved in bacteria
D3C60_05520	COG0840	transmembrane signaling receptor activity
D3C60_05525	COG2124	cytochrome p450
D3C60_05535	COG1307	EDD domain protein, DegV family
D3C60_05540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3C60_05555	COG0561	phosphatase activity
D3C60_05560	COG1073	alpha beta
D3C60_05565	COG2151	metal-sulfur cluster biosynthetic enzyme
D3C60_05575	COG0277	FAD linked oxidase domain protein
D3C60_05580	COG2271	Major facilitator Superfamily
D3C60_05600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3C60_05605	COG0505	Belongs to the CarA family
D3C60_05610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3C60_05615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D3C60_05635	COG2267	carboxylic ester hydrolase activity
D3C60_05645	COG1744	ABC transporter substrate-binding protein PnrA-like
D3C60_05660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3C60_05665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3C60_05670	COG5504	Zn-dependent protease
D3C60_05675	COG0444	Belongs to the ABC transporter superfamily
D3C60_05680	COG4608	Belongs to the ABC transporter superfamily
D3C60_05690	COG0601	transmembrane transport
D3C60_05695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3C60_05705	COG0180	Tryptophanyl-tRNA synthetase
D3C60_05710	COG4166	transmembrane transport
D3C60_05715	COG0601	transmembrane transport
D3C60_05720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3C60_05725	COG0444	Belongs to the ABC transporter superfamily
D3C60_05730	COG4608	Belongs to the ABC transporter superfamily
D3C60_05740	COG0456	acetyltransferase
D3C60_05745	COG1393	Belongs to the ArsC family
D3C60_05750	COG0861	Integral membrane protein TerC family
D3C60_05755	COG4862	establishment of competence for transformation
D3C60_05760	COG4469	Competence protein
D3C60_05765	COG1164	Oligoendopeptidase f
D3C60_05775	COG2346	COG2346, Truncated hemoglobins
D3C60_05780	COG0741	lytic transglycosylase activity
D3C60_05785	COG4116	CYTH
D3C60_05795	COG2357	RelA SpoT domain protein
D3C60_05800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3C60_05805	COG0564	pseudouridine synthase activity
D3C60_05820	COG0475	glutathione-regulated potassium exporter activity
D3C60_05820	COG0569	domain protein
D3C60_05825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D3C60_05830	COG0352	thiamine-phosphate diphosphorylase activity
D3C60_05835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3C60_05840	COG2104	thiamine diphosphate biosynthetic process
D3C60_05850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3C60_05855	COG0351	phosphomethylpyrimidine kinase
D3C60_05860	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D3C60_05915	COG0210	DNA helicase
D3C60_05935	COG1131	(ABC) transporter
D3C60_05945	COG2153	protein acetylation
D3C60_05955	COG2382	esterase
D3C60_05960	COG0626	cystathionine gamma-synthase activity
D3C60_05965	COG0626	cystathionine gamma-synthase activity
D3C60_06010	COG5444	nuclease activity
D3C60_06025	COG2367	Beta-lactamase
D3C60_06030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3C60_06035	COG2814	Major facilitator Superfamily
D3C60_06040	COG1846	Transcriptional regulator
D3C60_06050	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D3C60_06055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D3C60_06060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D3C60_06065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3C60_06065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3C60_06070	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3C60_06105	COG1285	pathogenesis
D3C60_06120	COG2205	protein histidine kinase activity
D3C60_06130	COG3383	formate dehydrogenase (NAD+) activity
D3C60_06135	COG2427	Protein of unknown function (DUF1641)
D3C60_06140	COG2124	cytochrome p450
D3C60_06145	COG1819	glycosyl
D3C60_06155	COG1587	Uroporphyrinogen-III synthase
D3C60_06160	COG0390	transport system, permease component
D3C60_06165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3C60_06170	COG0697	spore germination
D3C60_06175	COG4297	protein containing double-stranded beta helix domain
D3C60_06185	COG1252	NADH dehydrogenase
D3C60_06195	COG2211	Major facilitator Superfamily
D3C60_06200	COG1609	Transcriptional regulator
D3C60_06205	COG0246	Mannitol dehydrogenase
D3C60_06210	COG2721	sulfolactate sulfo-lyase activity
D3C60_06215	COG0730	response to heat
D3C60_06220	COG2318	DinB family
D3C60_06225	COG0457	Tetratricopeptide repeat
D3C60_06230	COG1388	LysM domain
D3C60_06230	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_06230	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3C60_06240	COG4195	phage-related replication protein
D3C60_06245	COG2856	Zn peptidase
D3C60_06250	COG1396	sequence-specific DNA binding
D3C60_06260	COG1522	sequence-specific DNA binding
D3C60_06265	COG1484	DNA-dependent DNA replication
D3C60_06280	COG1595	DNA-templated transcription, initiation
D3C60_06285	COG5484	DNA packaging
D3C60_06285	COG3728	DNA packaging
D3C60_06290	COG1783	phage Terminase large subunit
D3C60_06295	COG5518	Phage portal protein
D3C60_06300	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D3C60_06305	COG4653	Phage capsid family
D3C60_06355	COG5412	phage tail tape measure protein
D3C60_06355	COG3953	SLT domain
D3C60_06355	COG3953	SLT domain
D3C60_06355	COG3953	SLT domain
D3C60_06355	COG5412	phage tail tape measure protein
D3C60_06355	COG5412	phage tail tape measure protein
D3C60_06360	COG1652	LysM domain
D3C60_06365	COG4193	domain, Protein
D3C60_06375	COG3628	GPW Gp25 family protein
D3C60_06380	COG3299	homolog of phage Mu protein gp47
D3C60_06385	COG3778	Protein conserved in bacteria
D3C60_06425	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_06425	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3C60_06440	COG0306	phosphate transporter
D3C60_06445	COG1392	Phosphate transport regulator
D3C60_06450	COG0531	amino acid
D3C60_06455	COG0346	lactoylglutathione lyase activity
D3C60_06460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D3C60_06465	COG0463	Glycosyl transferase, family 2
D3C60_06470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3C60_06475	COG0477	Major facilitator Superfamily
D3C60_06480	COG2362	D-Aminopeptidase
D3C60_06485	COG0601	transmembrane transport
D3C60_06490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3C60_06495	COG0444	Belongs to the ABC transporter superfamily
D3C60_06500	COG4166	transmembrane transport
D3C60_06505	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3C60_06510	COG4948	Mandelate Racemase Muconate Lactonizing
D3C60_06515	COG0791	NLP P60 protein
D3C60_06520	COG4608	Belongs to the ABC transporter superfamily
D3C60_06525	COG2706	6-phosphogluconolactonase activity
D3C60_06530	COG1834	amidinotransferase
D3C60_06535	COG1607	acyl-coa hydrolase
D3C60_06540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3C60_06545	COG2076	Multidrug Resistance protein
D3C60_06550	COG2076	Multidrug Resistance protein
D3C60_06555	COG0788	formyltetrahydrofolate deformylase activity
D3C60_06560	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3C60_06570	COG1764	response to oxidative stress
D3C60_06575	COG1846	Transcriptional regulator
D3C60_06580	COG1764	response to oxidative stress
D3C60_06595	COG0463	Glycosyl transferase, family 2
D3C60_06595	COG0457	Tetratricopeptide repeat
D3C60_06605	COG2814	Major facilitator Superfamily
D3C60_06610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3C60_06620	COG1404	Belongs to the peptidase S8 family
D3C60_06625	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_06630	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D3C60_06635	COG1122	ATPase activity
D3C60_06640	COG4721	ABC-type cobalt transport system, permease component
D3C60_06645	COG1388	LysM domain
D3C60_06645	COG3858	chitin binding
D3C60_06665	COG2239	Acts as a magnesium transporter
D3C60_06670	COG0789	Transcriptional regulator
D3C60_06685	COG1846	Transcriptional regulator
D3C60_06690	COG0726	polysaccharide deacetylase
D3C60_06695	COG1793	dna ligase
D3C60_06695	COG3285	dna ligase
D3C60_06700	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D3C60_06705	COG0586	Pfam SNARE associated Golgi protein
D3C60_06710	COG0861	Integral membrane protein TerC family
D3C60_06715	COG1191	sigma factor activity
D3C60_06740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3C60_06745	COG2323	membrane
D3C60_06755	COG3594	Acyltransferase
D3C60_06760	COG5002	protein histidine kinase activity
D3C60_06765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3C60_06780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3C60_06785	COG0436	Aminotransferase
D3C60_06815	COG3852	Histidine kinase
D3C60_06820	COG1846	Transcriptional regulator
D3C60_06825	COG1360	Flagellar Motor Protein
D3C60_06830	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3C60_06835	COG0542	response to heat
D3C60_06845	COG3949	Membrane
D3C60_06860	COG0720	synthase
D3C60_06865	COG0602	queuosine metabolic process
D3C60_06875	COG1733	regulation of RNA biosynthetic process
D3C60_06880	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_06890	COG4641	Protein conserved in bacteria
D3C60_06890	COG1388	LysM domain
D3C60_06895	COG1388	LysM domain
D3C60_06900	COG3858	chitin binding
D3C60_06915	COG4873	Protein conserved in bacteria
D3C60_06925	COG3773	Cell wall hydrolase
D3C60_06930	COG2244	polysaccharide biosynthetic process
D3C60_06935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_06940	COG2217	Heavy metal translocating P-type atpase
D3C60_06945	COG0006	proline dipeptidase activity
D3C60_06950	COG1609	Transcriptional regulator
D3C60_06955	COG3711	transcriptional antiterminator
D3C60_06960	COG2190	(PTS) system
D3C60_06960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3C60_06960	COG1263	PTS System
D3C60_06965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3C60_06970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3C60_06980	COG1533	DNA photolyase activity
D3C60_06985	COG0840	transmembrane signaling receptor activity
D3C60_06990	COG2084	Dehydrogenase
D3C60_06995	COG2340	Cysteine-rich secretory protein family
D3C60_07000	COG0768	penicillin binding
D3C60_07005	COG4191	Histidine kinase
D3C60_07010	COG0436	Aminotransferase
D3C60_07020	COG0784	Response regulator, receiver
D3C60_07020	COG0835	chemotaxis
D3C60_07030	COG2814	Major facilitator Superfamily
D3C60_07035	COG1376	ErfK ybiS ycfS ynhG family protein
D3C60_07040	COG1408	metallophosphoesterase
D3C60_07045	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_07055	COG2200	EAL domain
D3C60_07060	COG4703	Protein of unknown function (DUF1797)
D3C60_07065	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D3C60_07075	COG0517	IMP dehydrogenase activity
D3C60_07080	COG0583	DNA-binding transcription factor activity
D3C60_07085	COG0716	FMN binding
D3C60_07095	COG0716	FMN binding
D3C60_07115	COG0668	transmembrane transport
D3C60_07120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_07140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3C60_07145	COG0303	'Molybdopterin
D3C60_07150	COG1763	Mo-molybdopterin cofactor biosynthetic process
D3C60_07155	COG0314	molybdopterin synthase activity
D3C60_07160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D3C60_07170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3C60_07175	COG1136	(ABC) transporter
D3C60_07180	COG0577	efflux transmembrane transporter activity
D3C60_07185	COG1349	DNA-binding transcription factor activity
D3C60_07190	COG1105	Belongs to the carbohydrate kinase PfkB family
D3C60_07195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3C60_07195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3C60_07195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3C60_07200	COG0681	Belongs to the peptidase S26 family
D3C60_07210	COG0488	(ABC) transporter
D3C60_07215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3C60_07220	COG2309	aminopeptidase activity
D3C60_07230	COG1077	Cell shape determining protein MreB Mrl
D3C60_07240	COG2002	toxin-antitoxin pair type II binding
D3C60_07245	COG3852	Histidine kinase
D3C60_07250	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D3C60_07250	COG2105	PFAM AIG2 family protein
D3C60_07255	COG0569	domain protein
D3C60_07270	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3C60_07280	COG0561	phosphatase activity
D3C60_07285	COG0242	peptide deformylase activity
D3C60_07295	COG0497	DNA recombination
D3C60_07310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_07310	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_07310	COG3321	synthase
D3C60_07310	COG4221	oxidoreductase activity
D3C60_07315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_07315	COG0300	oxidoreductase activity
D3C60_07315	COG3321	synthase
D3C60_07315	COG4221	oxidoreductase activity
D3C60_07320	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_07320	COG3321	synthase
D3C60_07320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_07320	COG4221	oxidoreductase activity
D3C60_07325	COG3321	synthase
D3C60_07325	COG4221	oxidoreductase activity
D3C60_07325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_07325	COG0300	oxidoreductase activity
D3C60_07330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_07330	COG0300	oxidoreductase activity
D3C60_07330	COG4221	oxidoreductase activity
D3C60_07330	COG3321	synthase
D3C60_07335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_07335	COG0300	oxidoreductase activity
D3C60_07335	COG3321	synthase
D3C60_07335	COG4221	oxidoreductase activity
D3C60_07340	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_07340	COG3321	synthase
D3C60_07340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_07340	COG4221	oxidoreductase activity
D3C60_07345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3C60_07350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3C60_07355	COG0022	dehydrogenase e1 component
D3C60_07360	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3C60_07365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3C60_07370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_07385	COG1982	Orn Lys Arg decarboxylase major
D3C60_07410	COG0483	inositol monophosphate 1-phosphatase activity
D3C60_07420	COG3227	Zinc metalloprotease (Elastase)
D3C60_07455	COG4896	Protein conserved in bacteria
D3C60_07465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D3C60_07470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3C60_07475	COG2066	Belongs to the glutaminase family
D3C60_07485	COG0772	Belongs to the SEDS family
D3C60_07490	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D3C60_07505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3C60_07505	COG2010	Cytochrome c
D3C60_07510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3C60_07515	COG1845	cytochrome c oxidase, subunit III
D3C60_07520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3C60_07525	COG3336	cytochrome c oxidase
D3C60_07540	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D3C60_07545	COG2340	Cysteine-rich secretory protein family
D3C60_07560	COG3679	Belongs to the UPF0342 family
D3C60_07575	COG0742	ribosomal rna small subunit methyltransferase
D3C60_07585	COG3314	Sporulation integral membrane protein YlbJ
D3C60_07590	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3C60_07595	COG3480	Lon protease (S16) C-terminal proteolytic domain
D3C60_07605	COG1399	metal-binding, possibly nucleic acid-binding protein
D3C60_07610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D3C60_07625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3C60_07645	COG4839	cell division protein FtsL
D3C60_07655	COG0768	penicillin binding
D3C60_07675	COG0772	Belongs to the SEDS family
D3C60_07690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D3C60_07695	COG0849	cell division
D3C60_07700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D3C60_07705	COG1404	Belongs to the peptidase S8 family
D3C60_07705	COG4412	M6 family metalloprotease domain protein
D3C60_07715	COG1191	sigma factor activity
D3C60_07720	COG1191	sigma factor activity
D3C60_07725	COG1119	ATPase activity
D3C60_07730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3C60_07735	COG1873	PFAM PRC-barrel domain
D3C60_07745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D3C60_07755	COG0762	integral membrane protein
D3C60_07760	COG2302	S4 RNA-binding domain
D3C60_07765	COG3599	regulation of cell shape
D3C60_07775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D3C60_07780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3C60_07790	COG0564	pseudouridine synthase activity
D3C60_07800	COG2233	PERMEase
D3C60_07810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D3C60_07815	COG0505	Belongs to the CarA family
D3C60_07820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3C60_07835	COG0284	orotidine-5'-phosphate decarboxylase activity
D3C60_07840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3C60_07850	COG0306	phosphate transporter
D3C60_07865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3C60_07870	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D3C60_07875	COG1648	precorrin-2 dehydrogenase activity
D3C60_07890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D3C60_07895	COG1561	YicC-like family, N-terminal region
D3C60_07900	COG2052	Domain of unknown function (DUF370)
D3C60_07905	COG0194	GDP metabolic process
D3C60_07915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3C60_07920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3C60_07925	COG0242	peptide deformylase activity
D3C60_07935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D3C60_07935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3C60_07945	COG0631	protein serine/threonine phosphatase activity
D3C60_07950	COG0515	serine threonine protein kinase
D3C60_07950	COG2815	serine threonine protein kinase
D3C60_07960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3C60_07965	COG1564	THIamine pyrophosphokinase
D3C60_07980	COG1302	Protein conserved in bacteria
D3C60_07985	COG1461	Dihydroxyacetone kinase
D3C60_07990	COG1760	l-serine dehydratase
D3C60_07995	COG1760	l-serine dehydratase
D3C60_08000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3C60_08015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3C60_08020	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_08025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_08035	COG1196	nuclear chromosome segregation
D3C60_08040	COG0552	protein localization to endoplasmic reticulum
D3C60_08055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3C60_08065	COG1837	Belongs to the UPF0109 family
D3C60_08090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D3C60_08105	COG2257	FlhB HrpN YscU SpaS Family
D3C60_08115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3C60_08120	COG0758	DNA mediated transformation
D3C60_08125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3C60_08135	COG4974	Belongs to the 'phage' integrase family
D3C60_08155	COG1815	bacterial-type flagellum-dependent cell motility
D3C60_08160	COG1558	bacterial-type flagellum-dependent cell motility
D3C60_08165	COG1677	Flagellar hook-basal body complex protein FliE
D3C60_08170	COG1766	The M ring may be actively involved in energy transduction
D3C60_08175	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3C60_08180	COG1317	bacterial-type flagellum organization
D3C60_08185	COG1157	protein secretion by the type III secretion system
D3C60_08190	COG2882	bacterial-type flagellum organization
D3C60_08195	COG3334	PFAM MgtE intracellular
D3C60_08200	COG3144	bacterial-type flagellum assembly
D3C60_08205	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D3C60_08210	COG4786	Flagellar basal body rod
D3C60_08215	COG1582	Flagellar protein (FlbD)
D3C60_08220	COG1580	Controls the rotational direction of flagella during chemotaxis
D3C60_08225	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3C60_08230	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D3C60_08230	COG1776	CheC inhibitor of MCP methylation
D3C60_08235	COG2201	protein-glutamate methylesterase activity
D3C60_08240	COG3190	flagellar
D3C60_08245	COG1338	Plays a role in the flagellum-specific transport system
D3C60_08250	COG1987	bacterial-type flagellum assembly
D3C60_08255	COG1684	flagellar biosynthetic protein fliR
D3C60_08260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3C60_08265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3C60_08270	COG1419	protein localization to endoplasmic reticulum
D3C60_08275	COG0455	bacterial-type flagellum organization
D3C60_08280	COG2201	protein-glutamate methylesterase activity
D3C60_08285	COG0643	Histidine kinase
D3C60_08285	COG2198	Histidine kinase
D3C60_08290	COG0835	chemotaxis
D3C60_08295	COG1776	CheC inhibitor of MCP methylation
D3C60_08305	COG1191	sigma factor activity
D3C60_08335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3C60_08340	COG4589	Belongs to the CDS family
D3C60_08350	COG0750	zinc metalloprotease
D3C60_08360	COG2176	DNA-directed DNA polymerase activity
D3C60_08370	COG0195	Participates in both transcription termination and antitermination
D3C60_08375	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D3C60_08380	COG1358	cellular component organization or biogenesis
D3C60_08390	COG1550	Protein conserved in bacteria
D3C60_08405	COG0196	riboflavin kinase activity
D3C60_08420	COG0726	polysaccharide deacetylase
D3C60_08425	COG0612	Peptidase, M16
D3C60_08430	COG1873	PFAM PRC-barrel domain
D3C60_08435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3C60_08440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3C60_08445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3C60_08450	COG0527	aspartate kinase activity
D3C60_08460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D3C60_08465	COG0740	serine-type endopeptidase activity
D3C60_08475	COG4980	gas vesicle protein
D3C60_08475	COG1674	ftsk spoiiie
D3C60_08480	COG2188	Transcriptional regulator
D3C60_08485	COG2814	Major facilitator Superfamily
D3C60_08490	COG1846	Transcriptional regulator
D3C60_08495	COG1033	growth of symbiont in host cell
D3C60_08495	COG2409	Drug exporters of the RND superfamily
D3C60_08500	COG0612	Peptidase, M16
D3C60_08505	COG0612	Peptidase, M16
D3C60_08510	COG0300	oxidoreductase activity
D3C60_08525	COG1426	Protein conserved in bacteria
D3C60_08530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3C60_08545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3C60_08555	COG1692	metallophosphoesterase
D3C60_08560	COG2359	stage V sporulation protein S
D3C60_08580	COG4550	Control of competence regulator ComK, YlbF/YmcA
D3C60_08600	COG0582	viral genome integration into host DNA
D3C60_08650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_08655	COG3425	synthase
D3C60_08660	COG1024	Enoyl-CoA hydratase
D3C60_08665	COG1024	Enoyl-CoA hydratase
D3C60_08670	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_08670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_08670	COG0300	oxidoreductase activity
D3C60_08670	COG3321	synthase
D3C60_08670	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_08675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_08675	COG0300	oxidoreductase activity
D3C60_08675	COG4221	oxidoreductase activity
D3C60_08675	COG3321	synthase
D3C60_08680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_08680	COG3321	synthase
D3C60_08680	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_08680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_08680	COG3321	synthase
D3C60_08680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_08680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_08680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_08680	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_08680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_08685	COG4221	oxidoreductase activity
D3C60_08685	COG3321	synthase
D3C60_08685	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_08685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_08690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3C60_08690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_08690	COG3321	synthase
D3C60_08690	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D3C60_08695	COG2124	cytochrome p450
D3C60_08700	COG3209	COG3209 Rhs family protein
D3C60_08705	COG3619	membrane
D3C60_08715	COG1404	Belongs to the peptidase S8 family
D3C60_08725	COG4195	phage-related replication protein
D3C60_08730	COG1764	response to oxidative stress
D3C60_08740	COG2076	Multidrug Resistance protein
D3C60_08780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3C60_08785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3C60_08790	COG4112	unkown
D3C60_08795	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3C60_08805	COG0464	growth
D3C60_08810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3C60_08815	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D3C60_08820	COG0789	Transcriptional regulator
D3C60_08825	COG0174	glutamine synthetase
D3C60_08835	COG2211	Major facilitator Superfamily
D3C60_08840	COG3507	Belongs to the glycosyl hydrolase 43 family
D3C60_08855	COG1070	Carbohydrate kinase
D3C60_08860	COG0574	Belongs to the PEP-utilizing enzyme family
D3C60_08860	COG3848	Pyruvate phosphate dikinase
D3C60_08885	COG1064	alcohol dehydrogenase
D3C60_08900	COG0456	acetyltransferase
D3C60_08940	COG3397	chitin binding
D3C60_08950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3C60_08960	COG5434	Belongs to the glycosyl hydrolase 28 family
D3C60_08965	COG0756	dUTP diphosphatase activity
D3C60_08975	COG4195	phage-related replication protein
D3C60_09005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3C60_09015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D3C60_09035	COG0785	Cytochrome C biogenesis protein
D3C60_09040	COG2201	protein-glutamate methylesterase activity
D3C60_09045	COG4846	Membrane protein involved in cytochrome C biogenesis
D3C60_09055	COG0071	Belongs to the small heat shock protein (HSP20) family
D3C60_09070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3C60_09075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_09095	COG0824	Thioesterase
D3C60_09105	COG4841	protein insertion into membrane
D3C60_09115	COG1832	CoA-binding protein
D3C60_09120	COG0187	DNA topoisomerase II activity
D3C60_09125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3C60_09135	COG1115	amino acid carrier protein
D3C60_09145	COG1063	alcohol dehydrogenase
D3C60_09150	COG0800	Aldolase
D3C60_09155	COG1312	Catalyzes the dehydration of D-mannonate
D3C60_09160	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_09165	COG1609	Transcriptional regulator
D3C60_09170	COG2271	Major facilitator Superfamily
D3C60_09215	COG2205	protein histidine kinase activity
D3C60_09220	COG0745	RESPONSE REGULATOR receiver
D3C60_09230	COG3507	Belongs to the glycosyl hydrolase 43 family
D3C60_09255	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_09260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3C60_09265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3C60_09270	COG2610	gluconate transmembrane transporter activity
D3C60_09275	COG2124	cytochrome p450
D3C60_09280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D3C60_09295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3C60_09305	COG2246	polysaccharide biosynthetic process
D3C60_09310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3C60_09315	COG0586	Pfam SNARE associated Golgi protein
D3C60_09320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3C60_09325	COG1024	Enoyl-CoA hydratase
D3C60_09330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D3C60_09335	COG0511	ligase activity, forming carbon-carbon bonds
D3C60_09340	COG0439	Biotin carboxylase
D3C60_09345	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_09350	COG1960	acyl-CoA dehydrogenase activity
D3C60_09355	COG1649	PFAM Uncharacterised BCR, COG1649
D3C60_09365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_09365	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D3C60_09370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_09375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_09380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_09385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_09395	COG2027	D-alanyl-D-alanine carboxypeptidase
D3C60_09400	COG2017	converts alpha-aldose to the beta-anomer
D3C60_09405	COG0534	Mate efflux family protein
D3C60_09420	COG0582	viral genome integration into host DNA
D3C60_09425	COG0166	Belongs to the GPI family
D3C60_09430	COG0405	Gamma-glutamyltransferase
D3C60_09435	COG2814	Major facilitator Superfamily
D3C60_09440	COG0640	Transcriptional regulator
D3C60_09445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3C60_09460	COG0604	alcohol dehydrogenase
D3C60_09470	COG0493	'glutamate synthase
D3C60_09475	COG0067	glutamate synthase
D3C60_09475	COG0069	glutamate synthase activity
D3C60_09475	COG0070	glutamate synthase
D3C60_09480	COG0583	DNA-binding transcription factor activity
D3C60_09485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3C60_09500	COG0300	oxidoreductase activity
D3C60_09505	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D3C60_09515	COG2814	Major facilitator Superfamily
D3C60_09520	COG1070	Carbohydrate kinase
D3C60_09525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3C60_09530	COG0243	molybdopterin cofactor binding
D3C60_09565	COG4974	Belongs to the 'phage' integrase family
D3C60_09620	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3C60_09625	COG4824	toxin secretion phage lysis holin
D3C60_09645	COG5434	Belongs to the glycosyl hydrolase 28 family
D3C60_09660	COG3953	SLT domain
D3C60_09660	COG5412	phage tail tape measure protein
D3C60_09790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3C60_09795	COG0662	Cupin 2, conserved barrel domain protein
D3C60_09795	COG2207	Transcriptional regulator
D3C60_09800	COG1309	transcriptional regulator
D3C60_09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3C60_09815	COG0640	Transcriptional regulator
D3C60_09820	COG0741	lytic transglycosylase activity
D3C60_09825	COG2322	membrane
D3C60_09840	COG1619	proteins homologs of microcin C7 resistance protein MccF
D3C60_09850	COG3584	3D domain protein
D3C60_09850	COG1388	LysM domain
D3C60_09855	COG0514	ATP-dependent DNA helicase (RecQ)
D3C60_09865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D3C60_09870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3C60_09885	COG0071	Belongs to the small heat shock protein (HSP20) family
D3C60_09915	COG1012	belongs to the aldehyde dehydrogenase family
D3C60_09920	COG1657	PFAM Prenyltransferase squalene oxidase
D3C60_09925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3C60_09930	COG0733	neurotransmitter:sodium symporter activity
D3C60_09935	COG0385	Bile acid
D3C60_09940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3C60_09945	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3C60_09955	COG4548	von Willebrand factor, type A
D3C60_09960	COG0714	Associated with various cellular activities
D3C60_09965	COG2032	superoxide dismutase activity
D3C60_09970	COG1388	LysM domain
D3C60_09970	COG0791	NLP P60 protein
D3C60_09975	COG1819	glycosyl
D3C60_09980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D3C60_09985	COG0534	Mate efflux family protein
D3C60_09990	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_09995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3C60_10000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3C60_10010	COG2962	Rard protein
D3C60_10025	COG1942	4-Oxalocrotonate Tautomerase
D3C60_10035	COG1733	regulation of RNA biosynthetic process
D3C60_10040	COG0778	Nitroreductase
D3C60_10045	COG0400	carboxylic ester hydrolase activity
D3C60_10050	COG0346	lactoylglutathione lyase activity
D3C60_10060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3C60_10070	COG2723	6-phospho-beta-galactosidase activity
D3C60_10075	COG2188	Transcriptional regulator
D3C60_10080	COG0793	Belongs to the peptidase S41A family
D3C60_10080	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_10085	COG2226	methyltransferase
D3C60_10095	COG1876	peptidase activity
D3C60_10115	COG0671	phosphoesterase, PA-phosphatase related
D3C60_10145	COG1509	lysine 2,3-aminomutase activity
D3C60_10150	COG0456	acetyltransferase
D3C60_10155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3C60_10160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D3C60_10165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D3C60_10170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D3C60_10185	COG0456	acetyltransferase
D3C60_10190	COG0463	Glycosyl transferase, family 2
D3C60_10205	COG4641	Protein conserved in bacteria
D3C60_10215	COG1086	Polysaccharide biosynthesis protein
D3C60_10245	COG1388	LysM domain
D3C60_10250	COG0457	Tetratricopeptide repeat
D3C60_10270	COG5444	nuclease activity
D3C60_10275	COG4282	regulation of fungal-type cell wall biogenesis
D3C60_10280	COG1525	nuclease
D3C60_10285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D3C60_10305	COG1846	Transcriptional regulator
D3C60_10310	COG4698	Protein conserved in bacteria
D3C60_10315	COG2755	lipolytic protein G-D-S-L family
D3C60_10320	COG1999	signal sequence binding
D3C60_10330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D3C60_10335	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3C60_10340	COG1272	protein, Hemolysin III
D3C60_10345	COG0204	Acyl-transferase
D3C60_10350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3C60_10365	COG2521	methyltransferase
D3C60_10365	COG2136	Putative SAM-dependent methyltransferase
D3C60_10380	COG1413	lyase activity
D3C60_10385	COG1418	mRNA catabolic process
D3C60_10390	COG0386	Belongs to the glutathione peroxidase family
D3C60_10400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3C60_10405	COG1278	Cold shock
D3C60_10425	COG0328	RNA-DNA hybrid ribonuclease activity
D3C60_10430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D3C60_10435	COG0328	RNA-DNA hybrid ribonuclease activity
D3C60_10445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3C60_10460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3C60_10470	COG1755	Isoprenylcysteine carboxyl methyltransferase
D3C60_10475	COG3424	synthase
D3C60_10500	COG1335	isochorismatase
D3C60_10510	COG2233	PERMEase
D3C60_10520	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D3C60_10525	COG1199	ATP-dependent helicase activity
D3C60_10540	COG0116	Belongs to the methyltransferase superfamily
D3C60_10565	COG3359	exonuclease
D3C60_10570	COG1205	dead DEAH box helicase
D3C60_10570	COG1111	helicase
D3C60_10575	COG2190	(PTS) system
D3C60_10580	COG0071	Belongs to the small heat shock protein (HSP20) family
D3C60_10620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3C60_10620	COG4499	WXG100 protein secretion system (Wss), protein YukC
D3C60_10630	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3C60_10635	COG3935	DnaD domain protein
D3C60_10645	COG0436	Aminotransferase
D3C60_10650	COG5353	protein conserved in bacteria
D3C60_10660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3C60_10660	COG1199	ATP-dependent helicase activity
D3C60_10690	COG0438	transferase activity, transferring glycosyl groups
D3C60_10695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3C60_10710	COG1694	Mazg nucleotide pyrophosphohydrolase
D3C60_10715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3C60_10720	COG2140	Oxalate decarboxylase
D3C60_10730	COG4347	Protein of unknown function (DUF1405)
D3C60_10735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D3C60_10735	COG2010	Cytochrome c
D3C60_10740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D3C60_10745	COG0723	plastoquinol--plastocyanin reductase activity
D3C60_10760	COG0457	Tetratricopeptide repeat
D3C60_10770	COG0287	Prephenate dehydrogenase
D3C60_10805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D3C60_10810	COG4401	Chorismate mutase type I
D3C60_10825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D3C60_10830	COG0105	UTP biosynthetic process
D3C60_10835	COG0142	geranyltranstransferase activity
D3C60_10845	COG0142	geranyltranstransferase activity
D3C60_10860	COG0776	regulation of translation
D3C60_10865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D3C60_10905	COG0539	negative regulation of cytoplasmic translation
D3C60_10915	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D3C60_10920	COG2959	enzyme of heme biosynthesis
D3C60_10925	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_10925	COG3773	Cell wall hydrolase
D3C60_10930	COG2339	peptidase activity
D3C60_10935	COG0492	ferredoxin-NADP+ reductase activity
D3C60_10940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3C60_10945	COG4862	establishment of competence for transformation
D3C60_10950	COG1408	metallophosphoesterase
D3C60_10960	COG1388	LysM domain
D3C60_10965	COG1266	CAAX protease self-immunity
D3C60_10970	COG0514	ATP-dependent DNA helicase (RecQ)
D3C60_10975	COG4955	Helix-turn-helix domain
D3C60_10980	COG1141	Ferredoxin
D3C60_10985	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D3C60_10990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3C60_11000	COG1595	DNA-templated transcription, initiation
D3C60_11005	COG5002	protein histidine kinase activity
D3C60_11010	COG0745	RESPONSE REGULATOR receiver
D3C60_11015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3C60_11020	COG1333	cytochrome c biogenesis protein
D3C60_11025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_11030	COG1187	pseudouridine synthase activity
D3C60_11035	COG0700	Nucleoside recognition
D3C60_11040	COG2715	membrane protein required for spore maturation
D3C60_11045	COG1686	Belongs to the peptidase S11 family
D3C60_11070	COG1547	Domain of unknown function (DUF309)
D3C60_11080	COG0456	acetyltransferase
D3C60_11095	COG0307	riboflavin synthase, alpha
D3C60_11100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3C60_11100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3C60_11110	COG0681	Belongs to the peptidase S26 family
D3C60_11120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3C60_11125	COG4086	secreted protein
D3C60_11130	COG0019	diaminopimelate decarboxylase activity
D3C60_11135	COG0697	spore germination
D3C60_11150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3C60_11170	COG1191	sigma factor activity
D3C60_11180	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_11185	COG1686	Belongs to the peptidase S11 family
D3C60_11190	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D3C60_11195	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D3C60_11200	COG4974	Belongs to the 'phage' integrase family
D3C60_11210	COG0735	belongs to the Fur family
D3C60_11215	COG1300	Membrane
D3C60_11230	COG0281	malic enzyme
D3C60_11235	COG1757	Na H antiporter
D3C60_11240	COG1027	Aspartate ammonia-lyase
D3C60_11245	COG0252	asparaginase activity
D3C60_11250	COG1396	sequence-specific DNA binding
D3C60_11255	COG1379	DNA repair
D3C60_11260	COG0494	nUDIX hydrolase
D3C60_11270	COG0667	Aldo Keto reductase
D3C60_11280	COG1073	alpha beta
D3C60_11290	COG4918	Iron-sulphur cluster biosynthesis
D3C60_11295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D3C60_11295	COG0456	acetyltransferase
D3C60_11300	COG2329	Antibiotic biosynthesis monooxygenase
D3C60_11305	COG0456	acetyltransferase
D3C60_11310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3C60_11325	COG0628	permease
D3C60_11335	COG0346	lactoylglutathione lyase activity
D3C60_11345	COG3048	D-serine ammonia-lyase activity
D3C60_11350	COG0300	oxidoreductase activity
D3C60_11355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3C60_11360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3C60_11365	COG1024	Enoyl-CoA hydratase
D3C60_11370	COG3425	synthase
D3C60_11375	COG2124	cytochrome p450
D3C60_11380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_11380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_11380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_11380	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11380	COG3321	synthase
D3C60_11385	COG3321	synthase
D3C60_11385	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_11385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_11385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_11390	COG3321	synthase
D3C60_11390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_11390	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11390	COG0300	oxidoreductase activity
D3C60_11390	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_11395	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11395	COG0300	oxidoreductase activity
D3C60_11395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_11395	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_11395	COG3321	synthase
D3C60_11400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_11400	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_11400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_11400	COG3321	synthase
D3C60_11405	COG3321	synthase
D3C60_11405	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11405	COG0300	oxidoreductase activity
D3C60_11405	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_11405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_11410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3C60_11410	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_11410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_11410	COG3321	synthase
D3C60_11415	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_11420	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_11435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3C60_11435	COG2070	2-Nitropropane dioxygenase
D3C60_11445	COG0250	Participates in transcription elongation, termination and antitermination
D3C60_11470	COG0596	Alpha beta hydrolase
D3C60_11485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D3C60_11490	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3C60_11505	COG0706	membrane insertase activity
D3C60_11510	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3C60_11515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D3C60_11520	COG0346	lactoylglutathione lyase activity
D3C60_11525	COG1376	ErfK ybiS ycfS ynhG family protein
D3C60_11530	COG4129	membrane
D3C60_11535	COG1126	abc transporter atp-binding protein
D3C60_11540	COG0765	amino acid transport
D3C60_11545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3C60_11555	COG1597	lipid kinase activity
D3C60_11560	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3C60_11565	COG0022	dehydrogenase e1 component
D3C60_11570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D3C60_11575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3C60_11580	COG3426	butyrate kinase activity
D3C60_11585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3C60_11590	COG0280	phosphate acetyltransferase
D3C60_11595	COG3829	transcription factor binding
D3C60_11595	COG3290	protein histidine kinase activity
D3C60_11605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D3C60_11610	COG2079	MmgE PrpD family protein
D3C60_11615	COG0372	Belongs to the citrate synthase family
D3C60_11620	COG1960	acyl-CoA dehydrogenase activity
D3C60_11625	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3C60_11630	COG0183	Belongs to the thiolase family
D3C60_11635	COG0584	glycerophosphoryl diester phosphodiesterase
D3C60_11640	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3C60_11660	COG1902	pentaerythritol trinitrate reductase activity
D3C60_11675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3C60_11685	COG0745	RESPONSE REGULATOR receiver
D3C60_11690	COG0750	zinc metalloprotease
D3C60_11695	COG0497	DNA recombination
D3C60_11705	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D3C60_11715	COG0142	geranyltranstransferase activity
D3C60_11725	COG1570	exodeoxyribonuclease VII activity
D3C60_11740	COG1302	Protein conserved in bacteria
D3C60_11745	COG0439	Biotin carboxylase
D3C60_11750	COG0511	ligase activity, forming carbon-carbon bonds
D3C60_11790	COG3854	ATPases associated with a variety of cellular activities
D3C60_11805	COG0006	proline dipeptidase activity
D3C60_11815	COG3872	metal-dependent enzyme
D3C60_11825	COG1752	Esterase of the alpha-beta hydrolase superfamily
D3C60_11840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3C60_11860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3C60_11875	COG1396	sequence-specific DNA binding
D3C60_11885	COG0681	Belongs to the peptidase S26 family
D3C60_11910	COG4940	Competence protein ComGF
D3C60_11920	COG4970	Tfp pilus assembly protein FimT
D3C60_11925	COG4537	Required for transformation and DNA binding
D3C60_11930	COG1459	type II secretion system
D3C60_11935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3C60_11940	COG0598	Magnesium transport protein CorA
D3C60_11945	COG1253	flavin adenine dinucleotide binding
D3C60_11950	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_11960	COG1393	Belongs to the ArsC family
D3C60_11970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3C60_11980	COG0011	TIGRFAM Protein of
D3C60_11990	COG2866	Carboxypeptidase
D3C60_11995	COG1940	carbohydrate kinase activity
D3C60_12000	COG4483	Protein conserved in bacteria
D3C60_12005	COG1757	Na H antiporter
D3C60_12015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3C60_12020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3C60_12030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3C60_12035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3C60_12040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3C60_12045	COG0581	inorganic phosphate transmembrane transporter activity
D3C60_12050	COG0573	inorganic phosphate transmembrane transporter activity
D3C60_12055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3C60_12065	COG0477	Major facilitator Superfamily
D3C60_12070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3C60_12075	COG2839	Protein conserved in bacteria
D3C60_12080	COG5521	maltodextrose utilization protein MalA
D3C60_12085	COG1388	LysM domain
D3C60_12095	COG4709	membrane
D3C60_12100	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D3C60_12105	COG0735	belongs to the Fur family
D3C60_12110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3C60_12125	COG0513	Belongs to the DEAD box helicase family
D3C60_12140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D3C60_12145	COG2384	SAM-dependent methyltransferase
D3C60_12150	COG2010	Cytochrome c
D3C60_12155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3C60_12160	COG0358	DNA primase activity
D3C60_12175	COG0517	IMP dehydrogenase activity
D3C60_12180	COG0751	glycine-tRNA ligase activity
D3C60_12200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D3C60_12205	COG0295	cytidine deaminase activity
D3C60_12210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D3C60_12220	COG1480	7TM receptor with intracellular HD hydrolase
D3C60_12225	COG1702	phosphate starvation-inducible protein PhoH
D3C60_12230	COG0561	phosphatase activity
D3C60_12245	COG4864	UPF0365 protein
D3C60_12250	COG1030	water channel activity
D3C60_12255	COG1610	YqeY-like protein
D3C60_12260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3C60_12265	COG1283	sodium-dependent phosphate transmembrane transporter activity
D3C60_12275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3C60_12280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3C60_12310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3C60_12325	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3C60_12340	COG1466	dna polymerase III delta subunit
D3C60_12350	COG2333	competence protein COMEC
D3C60_12350	COG0658	competence protein
D3C60_12355	COG2131	deaminase
D3C60_12360	COG1555	photosystem II stabilization
D3C60_12360	COG1596	polysaccharide export
D3C60_12365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3C60_12370	COG2226	methyltransferase
D3C60_12375	COG0799	negative regulation of ribosome biogenesis
D3C60_12380	COG1713	HD superfamily hydrolase involved in NAD metabolism
D3C60_12390	COG1534	Rna-binding protein
D3C60_12395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3C60_12400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D3C60_12405	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D3C60_12415	COG2755	lipolytic protein G-D-S-L family
D3C60_12420	COG0726	polysaccharide deacetylase
D3C60_12425	COG0398	Pfam SNARE associated Golgi protein
D3C60_12460	COG3708	Transcriptional regulator
D3C60_12460	COG2207	Transcriptional regulator
D3C60_12470	COG0563	adenylate kinase activity
D3C60_12475	COG2814	Major facilitator Superfamily
D3C60_12485	COG0456	acetyltransferase
D3C60_12490	COG2318	DinB family
D3C60_12500	COG0561	phosphatase activity
D3C60_12505	COG0561	phosphatase activity
D3C60_12515	COG1482	cell wall glycoprotein biosynthetic process
D3C60_12520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3C60_12520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3C60_12520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D3C60_12525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3C60_12525	COG3711	transcriptional antiterminator
D3C60_12535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3C60_12540	COG0583	DNA-binding transcription factor activity
D3C60_12545	COG2814	Major facilitator Superfamily
D3C60_12550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3C60_12550	COG2124	cytochrome p450
D3C60_12555	COG1309	transcriptional regulator
D3C60_12560	COG2226	methyltransferase
D3C60_12575	COG2116	formate transmembrane transporter activity
D3C60_12580	COG5609	conserved protein (DUF2294)
D3C60_12585	COG3383	formate dehydrogenase (NAD+) activity
D3C60_12590	COG2427	Protein of unknown function (DUF1641)
D3C60_12605	COG0626	cystathionine gamma-synthase activity
D3C60_12610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3C60_12635	COG0768	penicillin binding
D3C60_12665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3C60_12690	COG0628	permease
D3C60_12695	COG1126	abc transporter atp-binding protein
D3C60_12700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3C60_12705	COG0765	amino acid transport
D3C60_12710	COG0765	amino acid transport
D3C60_12725	COG3881	PFAM PRC-barrel domain
D3C60_12730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3C60_12735	COG0457	Tetratricopeptide repeat
D3C60_12745	COG1104	cysteine desulfurase activity
D3C60_12750	COG1959	2 iron, 2 sulfur cluster binding
D3C60_12755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D3C60_12760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D3C60_12780	COG3103	Sh3 type 3 domain protein
D3C60_12780	COG4991	sh3 domain protein
D3C60_12780	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3C60_12790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3C60_12800	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D3C60_12800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3C60_12805	COG5416	Lipopolysaccharide assembly protein A domain
D3C60_12810	COG0490	domain, Protein
D3C60_12815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3C60_12815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3C60_12825	COG2244	polysaccharide biosynthetic process
D3C60_12830	COG2323	membrane
D3C60_12840	COG1862	Preprotein translocase
D3C60_12885	COG1388	LysM domain
D3C60_12895	COG0157	Belongs to the NadC ModD family
D3C60_12900	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D3C60_12905	COG1104	cysteine desulfurase activity
D3C60_12910	COG1827	regulation of RNA biosynthetic process
D3C60_12915	COG0077	Prephenate dehydratase
D3C60_12930	COG3290	protein histidine kinase activity
D3C60_12935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D3C60_12940	COG2868	ribosomal protein
D3C60_12950	COG1994	Peptidase M50
D3C60_12955	COG0739	heme binding
D3C60_12960	COG2894	cell division
D3C60_12970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D3C60_12975	COG1792	Involved in formation and maintenance of cell shape
D3C60_12980	COG1077	Cell shape determining protein MreB Mrl
D3C60_12995	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_12995	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3C60_12995	COG1388	LysM domain
D3C60_13000	COG4824	toxin secretion phage lysis holin
D3C60_13020	COG5434	Belongs to the glycosyl hydrolase 28 family
D3C60_13025	COG1705	Flagellar rod assembly protein muramidase FlgJ
D3C60_13035	COG5412	phage tail tape measure protein
D3C60_13035	COG3953	SLT domain
D3C60_13150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3C60_13150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3C60_13195	COG1396	sequence-specific DNA binding
D3C60_13225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D3C60_13230	COG0285	dihydrofolate synthase activity
D3C60_13235	COG0525	valine-tRNA ligase activity
D3C60_13245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3C60_13250	COG1388	LysM domain
D3C60_13260	COG0113	porphobilinogen synthase activity
D3C60_13265	COG1587	Uroporphyrinogen-III synthase
D3C60_13275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D3C60_13295	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D3C60_13300	COG0470	DNA polymerase III
D3C60_13300	COG1067	ATP-dependent peptidase activity
D3C60_13315	COG1477	protein flavinylation
D3C60_13315	COG0457	Tetratricopeptide repeat
D3C60_13330	COG0473	3-isopropylmalate dehydrogenase activity
D3C60_13345	COG0440	acetolactate synthase activity
D3C60_13350	COG0028	Belongs to the TPP enzyme family
D3C60_13375	COG0622	Phosphoesterase
D3C60_13380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3C60_13390	COG5401	PFAM Sporulation and spore germination
D3C60_13400	COG1846	Transcriptional regulator
D3C60_13405	COG2197	response regulator
D3C60_13410	COG0824	Thioesterase
D3C60_13415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3C60_13420	COG1053	succinate dehydrogenase
D3C60_13425	COG2009	succinate dehydrogenase
D3C60_13430	COG1719	4-vinyl reductase, 4VR
D3C60_13435	COG0527	aspartate kinase activity
D3C60_13450	COG3118	belongs to the thioredoxin family
D3C60_13455	COG3534	alpha-L-arabinofuranosidase
D3C60_13460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D3C60_13465	COG2086	electron transfer activity
D3C60_13470	COG1024	Enoyl-CoA hydratase
D3C60_13475	COG1309	transcriptional regulator
D3C60_13480	COG0318	PFAM AMP-dependent synthetase and ligase
D3C60_13490	COG3766	membrane
D3C60_13500	COG1796	DNA polymerase
D3C60_13500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D3C60_13505	COG1286	toxin biosynthetic process
D3C60_13520	COG0072	phenylalanine-tRNA ligase activity
D3C60_13520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3C60_13525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D3C60_13530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3C60_13540	COG3835	regulator
D3C60_13545	COG0277	FAD linked oxidase domain protein
D3C60_13550	COG0247	lactate metabolic process
D3C60_13555	COG1966	Carbon starvation protein
D3C60_13560	COG3534	alpha-L-arabinofuranosidase
D3C60_13565	COG0395	ABC-type sugar transport system, permease component
D3C60_13570	COG1175	transmembrane transport
D3C60_13575	COG1653	transport
D3C60_13585	COG0647	UMP catabolic process
D3C60_13590	COG0235	Class ii aldolase
D3C60_13595	COG1069	ribulokinase activity
D3C60_13600	COG2160	L-arabinose isomerase activity
D3C60_13605	COG3507	Belongs to the glycosyl hydrolase 43 family
D3C60_13610	COG1363	Peptidase, m42
D3C60_13620	COG3326	Membrane
D3C60_13625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D3C60_13635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3C60_13640	COG1346	cytolysis
D3C60_13645	COG1380	Effector of murein hydrolase LrgA
D3C60_13650	COG3279	Response regulator of the LytR AlgR family
D3C60_13655	COG3275	phosphorelay sensor kinase activity
D3C60_13680	COG0398	Pfam SNARE associated Golgi protein
D3C60_13685	COG1484	DNA-dependent DNA replication
D3C60_13690	COG3611	Membrane attachment protein
D3C60_13705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3C60_13710	COG1733	regulation of RNA biosynthetic process
D3C60_13715	COG2814	Major facilitator Superfamily
D3C60_13720	COG0656	L-ascorbic acid biosynthetic process
D3C60_13725	COG0237	dephospho-CoA kinase activity
D3C60_13730	COG1971	Probably functions as a manganese efflux pump
D3C60_13735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D3C60_13740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3C60_13740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3C60_13745	COG5002	protein histidine kinase activity
D3C60_13750	COG0745	RESPONSE REGULATOR receiver
D3C60_13760	COG0538	isocitrate dehydrogenase activity
D3C60_13765	COG0372	Belongs to the citrate synthase family
D3C60_13775	COG5632	N-Acetylmuramoyl-L-alanine amidase
D3C60_13785	COG0628	permease
D3C60_13790	COG3030	protein affecting phage T7 exclusion by the F plasmid
D3C60_13795	COG0469	pyruvate kinase activity
D3C60_13815	COG0281	malic enzyme
D3C60_13820	COG0587	DNA-directed DNA polymerase activity
D3C60_13840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D3C60_13850	COG4109	DRTGG domain
D3C60_13860	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_13875	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3C60_13885	COG0827	DNA restriction-modification system
D3C60_13890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D3C60_13895	COG3874	Sporulation protein YtfJ
D3C60_13905	COG1714	RDD family
D3C60_13910	COG0616	signal peptide processing
D3C60_13915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3C60_13920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D3C60_13925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3C60_13940	COG1104	cysteine desulfurase activity
D3C60_13945	COG1114	Component of the transport system for branched-chain amino acids
D3C60_13955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D3C60_13960	COG1309	transcriptional regulator
D3C60_13965	COG1956	GAF domain-containing protein
D3C60_13970	COG2199	diguanylate cyclase activity
D3C60_13970	COG2203	Gaf domain
D3C60_13985	COG1012	belongs to the aldehyde dehydrogenase family
D3C60_13990	COG4282	regulation of fungal-type cell wall biogenesis
D3C60_14030	COG1017	nitric oxide dioxygenase activity
D3C60_14030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3C60_14045	COG0693	protein deglycase activity
D3C60_14060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3C60_14065	COG1378	Sugar-specific transcriptional regulator TrmB
D3C60_14090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3C60_14095	COG0454	-acetyltransferase
D3C60_14100	COG0517	IMP dehydrogenase activity
D3C60_14105	COG0123	including yeast histone deacetylase and acetoin utilization protein
D3C60_14115	COG1360	Flagellar Motor Protein
D3C60_14120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3C60_14125	COG1609	Transcriptional regulator
D3C60_14130	COG1605	Chorismate mutase
D3C60_14130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D3C60_14135	COG3118	belongs to the thioredoxin family
D3C60_14140	COG4980	gas vesicle protein
D3C60_14145	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D3C60_14155	COG1674	ftsk spoiiie
D3C60_14160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3C60_14170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_14180	COG1363	Peptidase, m42
D3C60_14185	COG5584	Small secreted protein
D3C60_14190	COG0281	malic enzyme
D3C60_14195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3C60_14210	COG0510	thiamine kinase activity
D3C60_14215	COG1597	lipid kinase activity
D3C60_14225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D3C60_14230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3C60_14235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3C60_14240	COG2252	PERMEase
D3C60_14245	COG4473	ABC transporter
D3C60_14250	COG1131	(ABC) transporter
D3C60_14255	COG1349	DNA-binding transcription factor activity
D3C60_14260	COG1187	pseudouridine synthase activity
D3C60_14265	COG2244	polysaccharide biosynthetic process
D3C60_14270	COG2081	HI0933 family
D3C60_14275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3C60_14305	COG1486	melibiose metabolic process
D3C60_14315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3C60_14330	COG2202	Pas domain
D3C60_14330	COG1366	Belongs to the anti-sigma-factor antagonist family
D3C60_14335	COG2814	Major facilitator Superfamily
D3C60_14340	COG5522	Integral membrane protein (intg_mem_TP0381)
D3C60_14345	COG0577	efflux transmembrane transporter activity
D3C60_14350	COG1136	(ABC) transporter
D3C60_14355	COG2205	protein histidine kinase activity
D3C60_14360	COG0745	RESPONSE REGULATOR receiver
D3C60_14365	COG0577	efflux transmembrane transporter activity
D3C60_14370	COG1136	(ABC) transporter
D3C60_14390	COG1131	(ABC) transporter
D3C60_14395	COG1725	Transcriptional regulator
D3C60_14435	COG0477	Major facilitator Superfamily
D3C60_14440	COG1242	4 iron, 4 sulfur cluster binding
D3C60_14445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D3C60_14455	COG0584	glycerophosphoryl diester phosphodiesterase
D3C60_14465	COG2267	carboxylic ester hydrolase activity
D3C60_14470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3C60_14475	COG1113	amino acid transport
D3C60_14480	COG0367	asparagine synthase
D3C60_14500	COG1506	peptidase
D3C60_14505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D3C60_14510	COG1116	anion transmembrane transporter activity
D3C60_14515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D3C60_14520	COG0494	nUDIX hydrolase
D3C60_14525	COG4824	toxin secretion phage lysis holin
D3C60_14530	COG0783	Belongs to the Dps family
D3C60_14555	COG0288	reversible hydration of carbon dioxide
D3C60_14565	COG1271	oxidase subunit
D3C60_14570	COG1294	oxidase, subunit
D3C60_14585	COG4948	Mandelate Racemase Muconate Lactonizing
D3C60_14595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D3C60_14600	COG0596	Alpha beta hydrolase
D3C60_14610	COG1169	isochorismate synthase
D3C60_14615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D3C60_14620	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D3C60_14745	COG3859	Proton-coupled thiamine transporter YuaJ
D3C60_14750	COG2268	Band 7 protein
D3C60_14755	COG1585	Membrane protein implicated in regulation of membrane protease activity
D3C60_14760	COG2318	DinB family
D3C60_14770	COG1454	alcohol dehydrogenase
D3C60_14780	COG1510	regulation of RNA biosynthetic process
D3C60_14790	COG0569	domain protein
D3C60_14795	COG1705	Flagellar rod assembly protein muramidase FlgJ
D3C60_14800	COG1017	nitric oxide dioxygenase activity
D3C60_14800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3C60_14825	COG0628	permease
D3C60_14830	COG0673	inositol 2-dehydrogenase activity
D3C60_14835	COG0693	protein deglycase activity
D3C60_14840	COG0840	transmembrane signaling receptor activity
D3C60_14845	COG0840	transmembrane signaling receptor activity
D3C60_14850	COG0840	transmembrane signaling receptor activity
D3C60_14855	COG0840	transmembrane signaling receptor activity
D3C60_14870	COG2070	2-Nitropropane dioxygenase
D3C60_14875	COG0432	Pfam Uncharacterised protein family UPF0047
D3C60_14880	COG0366	Alpha amylase catalytic
D3C60_14885	COG1253	flavin adenine dinucleotide binding
D3C60_14890	COG2738	Putative neutral zinc metallopeptidase
D3C60_14905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3C60_14940	COG1979	alcohol dehydrogenase
D3C60_14945	COG1979	alcohol dehydrogenase
D3C60_14950	COG2155	Conserved Protein
D3C60_14955	COG1098	S1 RNA binding domain
D3C60_14960	COG0436	Aminotransferase
D3C60_14965	COG1522	sequence-specific DNA binding
D3C60_14970	COG2267	carboxylic ester hydrolase activity
D3C60_14980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D3C60_14985	COG2205	protein histidine kinase activity
D3C60_14995	COG5018	Exonuclease
D3C60_15000	COG2814	Major facilitator Superfamily
D3C60_15005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3C60_15010	COG3011	Protein conserved in bacteria
D3C60_15020	COG3290	protein histidine kinase activity
D3C60_15025	COG4565	transcriptional regulatory protein
D3C60_15055	COG2111	Na H antiporter
D3C60_15055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3C60_15060	COG2111	Na H antiporter
D3C60_15065	COG1006	Multisubunit Na H antiporter MnhC subunit
D3C60_15070	COG0651	ATP synthesis coupled electron transport
D3C60_15075	COG1863	multisubunit Na H antiporter MnhE subunit
D3C60_15080	COG2212	antiporter activity
D3C60_15085	COG1320	monovalent cation:proton antiporter activity
D3C60_15090	COG2050	protein possibly involved in aromatic compounds catabolism
D3C60_15095	COG2197	response regulator
D3C60_15100	COG4585	Histidine kinase
D3C60_15110	COG0142	geranyltranstransferase activity
D3C60_15130	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D3C60_15135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D3C60_15140	COG1335	isochorismatase
D3C60_15145	COG5506	Protein of unknown function (DUF1694)
D3C60_15160	COG0628	permease
D3C60_15170	COG1418	mRNA catabolic process
D3C60_15175	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_15185	COG1511	domain protein
D3C60_15190	COG0433	COG0433 Predicted ATPase
D3C60_15190	COG1674	ftsk spoiiie
D3C60_15195	COG4499	WXG100 protein secretion system (Wss), protein YukC
D3C60_15200	COG5417	Belongs to the EsaB family
D3C60_15205	COG4842	Belongs to the WXG100 family
D3C60_15210	COG2508	Transcriptional regulator
D3C60_15210	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D3C60_15215	COG0686	Belongs to the AlaDH PNT family
D3C60_15220	COG5634	Uncharacterized conserved protein (DUF2278)
D3C60_15225	COG3251	PFAM MbtH domain protein
D3C60_15230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3C60_15235	COG1535	isochorismatase
D3C60_15235	COG3433	isochorismatase activity
D3C60_15240	COG1021	2,3-dihydroxybenzoate-AMP ligase
D3C60_15245	COG1169	isochorismate synthase
D3C60_15250	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_15255	COG2819	hydrolase of the alpha beta superfamily
D3C60_15260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D3C60_15265	COG1268	BioY protein
D3C60_15270	COG2056	Na+-H+ antiporter family
D3C60_15280	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D3C60_15285	COG3584	3D domain protein
D3C60_15300	COG1252	NADH dehydrogenase
D3C60_15330	COG1131	(ABC) transporter
D3C60_15350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3C60_15355	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D3C60_15360	COG0316	Belongs to the HesB IscA family
D3C60_15370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3C60_15380	COG1252	NADH dehydrogenase
D3C60_15385	COG4837	Protein of unknown function (DUF1462)
D3C60_15390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D3C60_15395	COG1506	peptidase
D3C60_15395	COG0823	Involved in the tonB-independent uptake of proteins
D3C60_15395	COG4946	Tricorn protease homolog
D3C60_15405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D3C60_15410	COG0460	homoserine dehydrogenase
D3C60_15415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3C60_15420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D3C60_15425	COG0647	UMP catabolic process
D3C60_15430	COG2445	Protein of unknown function DUF86
D3C60_15435	COG4470	Protein conserved in bacteria
D3C60_15450	COG0739	heme binding
D3C60_15460	COG0737	Belongs to the 5'-nucleotidase family
D3C60_15465	COG0730	response to heat
D3C60_15470	COG1801	Protein of unknown function DUF72
D3C60_15485	COG2508	Transcriptional regulator
D3C60_15510	COG2814	Major facilitator Superfamily
D3C60_15515	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D3C60_15520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3C60_15525	COG2356	endonuclease I
D3C60_15530	COG3842	ATPase activity
D3C60_15535	COG2188	Transcriptional regulator
D3C60_15540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3C60_15545	COG0395	ABC-type sugar transport system, permease component
D3C60_15550	COG1175	transmembrane transport
D3C60_15555	COG1653	transport
D3C60_15560	COG2222	sugar isomerase
D3C60_15565	COG0789	Transcriptional regulator
D3C60_15595	COG0322	excinuclease ABC activity
D3C60_15600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3C60_15620	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_15625	COG0719	Fe-S assembly protein
D3C60_15630	COG0822	iron-sulfur transferase activity
D3C60_15635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3C60_15640	COG0719	Fe-S assembly protein
D3C60_15645	COG0396	ATPase activity
D3C60_15655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3C60_15660	COG1464	Belongs to the NlpA lipoprotein family
D3C60_15665	COG2011	ABC-type metal ion transport system permease component
D3C60_15670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3C60_15680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D3C60_15685	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D3C60_15700	COG1393	Belongs to the ArsC family
D3C60_15705	COG1960	acyl-CoA dehydrogenase activity
D3C60_15710	COG0183	Belongs to the thiolase family
D3C60_15715	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3C60_15715	COG1024	Enoyl-CoA hydratase
D3C60_15735	COG5577	PFAM Coat F domain
D3C60_15740	COG1846	Transcriptional regulator
D3C60_15745	COG0477	Major facilitator Superfamily
D3C60_15750	COG0583	DNA-binding transcription factor activity
D3C60_15770	COG1120	ATPase activity
D3C60_15785	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_15790	COG0783	Belongs to the Dps family
D3C60_15795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3C60_15800	COG0745	RESPONSE REGULATOR receiver
D3C60_15805	COG2770	Histidine kinase
D3C60_15805	COG2205	protein histidine kinase activity
D3C60_15815	COG1309	transcriptional regulator
D3C60_15820	COG0114	fumarate hydratase activity
D3C60_15830	COG0697	spore germination
D3C60_15835	COG0814	amino acid
D3C60_15845	COG2197	response regulator
D3C60_15850	COG4585	Histidine kinase
D3C60_15855	COG4758	membrane
D3C60_15860	COG3595	metallopeptidase activity
D3C60_15865	COG1842	Phage shock protein A
D3C60_15870	COG4758	membrane
D3C60_15875	COG2814	Major facilitator Superfamily
D3C60_15880	COG2096	Adenosyltransferase
D3C60_15885	COG1120	ATPase activity
D3C60_15890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_15895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3C60_15900	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_15905	COG3386	PFAM SMP-30 Gluconolaconase
D3C60_15910	COG2205	protein histidine kinase activity
D3C60_15915	COG0745	RESPONSE REGULATOR receiver
D3C60_15925	COG1191	sigma factor activity
D3C60_15935	COG2140	Oxalate decarboxylase
D3C60_15945	COG1120	ATPase activity
D3C60_15950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_15955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_15960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3C60_15965	COG0531	amino acid
D3C60_15980	COG1988	membrane-bound metal-dependent
D3C60_15985	COG1368	sulfuric ester hydrolase activity
D3C60_15990	COG1910	domain protein
D3C60_15995	COG0725	ABC transporter, periplasmic molybdate-binding protein
D3C60_16000	COG4149	molybdate abc transporter
D3C60_16005	COG2197	response regulator
D3C60_16010	COG3850	Histidine kinase
D3C60_16015	COG1131	(ABC) transporter
D3C60_16025	COG0842	Transport permease protein
D3C60_16030	COG0656	L-ascorbic acid biosynthetic process
D3C60_16060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3C60_16065	COG3973	AAA domain
D3C60_16070	COG2860	membrane
D3C60_16080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D3C60_16085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3C60_16090	COG2217	Heavy metal translocating P-type atpase
D3C60_16095	COG2217	Heavy metal translocating P-type atpase
D3C60_16100	COG2608	mercury ion transmembrane transporter activity
D3C60_16105	COG1937	Protein conserved in bacteria
D3C60_16110	COG0673	inositol 2-dehydrogenase activity
D3C60_16120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3C60_16125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D3C60_16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3C60_16135	COG1126	abc transporter atp-binding protein
D3C60_16140	COG0765	amino acid transport
D3C60_16145	COG0765	amino acid transport
D3C60_16150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3C60_16155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3C60_16160	COG0454	-acetyltransferase
D3C60_16165	COG0583	DNA-binding transcription factor activity
D3C60_16170	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_16175	COG2732	(Barnase) inhibitor
D3C60_16190	COG2732	(Barnase) inhibitor
D3C60_16205	COG0557	exoribonuclease II activity
D3C60_16210	COG1647	Serine aminopeptidase, S33
D3C60_16215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3C60_16220	COG1476	TRANSCRIPTIONal
D3C60_16225	COG1396	sequence-specific DNA binding
D3C60_16230	COG1396	sequence-specific DNA binding
D3C60_16235	COG1733	regulation of RNA biosynthetic process
D3C60_16265	COG1174	glycine betaine transport
D3C60_16270	COG1732	Glycine betaine
D3C60_16275	COG1174	glycine betaine transport
D3C60_16280	COG0517	IMP dehydrogenase activity
D3C60_16280	COG1125	glycine betaine transport
D3C60_16285	COG1510	regulation of RNA biosynthetic process
D3C60_16290	COG1174	glycine betaine transport
D3C60_16295	COG1732	Glycine betaine
D3C60_16300	COG1174	glycine betaine transport
D3C60_16305	COG0517	IMP dehydrogenase activity
D3C60_16305	COG1125	glycine betaine transport
D3C60_16310	COG1510	regulation of RNA biosynthetic process
D3C60_16315	COG2095	MarC family integral membrane protein
D3C60_16325	COG3064	Membrane
D3C60_16330	COG4640	response to antibiotic
D3C60_16335	COG0456	acetyltransferase
D3C60_16350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D3C60_16365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3C60_16370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3C60_16375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3C60_16385	COG2234	aminopeptidase activity
D3C60_16405	COG0126	phosphoglycerate kinase activity
D3C60_16415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3C60_16420	COG2390	Transcriptional regulator
D3C60_16425	COG2814	Major facilitator Superfamily
D3C60_16430	COG1609	Transcriptional regulator
D3C60_16435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3C60_16445	COG0583	DNA-binding transcription factor activity
D3C60_16450	COG0697	spore germination
D3C60_16455	COG1113	amino acid transport
D3C60_16460	COG1737	Transcriptional regulator
D3C60_16465	COG1070	Carbohydrate kinase
D3C60_16495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3C60_16500	COG2186	Transcriptional regulator
D3C60_16505	COG1620	l-lactate permease
D3C60_16510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D3C60_16520	COG5039	Polysaccharide pyruvyl transferase
D3C60_16525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3C60_16530	COG0110	maltose O-acetyltransferase activity
D3C60_16535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D3C60_16540	COG2244	polysaccharide biosynthetic process
D3C60_16545	COG1216	Glycosyl transferase, family 2
D3C60_16550	COG5039	Polysaccharide pyruvyl transferase
D3C60_16555	COG1216	Glycosyl transferase, family 2
D3C60_16565	COG0438	transferase activity, transferring glycosyl groups
D3C60_16570	COG1215	transferase activity, transferring glycosyl groups
D3C60_16575	COG0438	transferase activity, transferring glycosyl groups
D3C60_16580	COG1086	Polysaccharide biosynthesis protein
D3C60_16585	COG0489	protein tyrosine kinase activity
D3C60_16590	COG3944	biosynthesis protein
D3C60_16595	COG1396	sequence-specific DNA binding
D3C60_16600	COG2272	Belongs to the type-B carboxylesterase lipase family
D3C60_16605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D3C60_16610	COG2364	Membrane
D3C60_16615	COG0456	acetyltransferase
D3C60_16620	COG3479	Phenolic acid decarboxylase
D3C60_16670	COG2223	nitrite transmembrane transporter activity
D3C60_16675	COG1609	Transcriptional regulator
D3C60_16685	COG0583	DNA-binding transcription factor activity
D3C60_16690	COG2828	Protein conserved in bacteria
D3C60_16695	COG2814	Major facilitator Superfamily
D3C60_16695	COG0477	Major facilitator Superfamily
D3C60_16700	COG1611	Belongs to the LOG family
D3C60_16705	COG1694	Mazg nucleotide pyrophosphohydrolase
D3C60_16710	COG0659	secondary active sulfate transmembrane transporter activity
D3C60_16715	COG0288	reversible hydration of carbon dioxide
D3C60_16725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3C60_16730	COG4290	ribonuclease
D3C60_16735	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D3C60_16740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3C60_16750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D3C60_16760	COG1051	belongs to the nudix hydrolase family
D3C60_16765	COG0492	ferredoxin-NADP+ reductase activity
D3C60_16770	COG3883	PFAM NLP P60 protein
D3C60_16770	COG0791	NLP P60 protein
D3C60_16775	COG0457	Tetratricopeptide repeat
D3C60_16780	COG5002	protein histidine kinase activity
D3C60_16785	COG0745	RESPONSE REGULATOR receiver
D3C60_16790	COG1132	(ABC) transporter
D3C60_16795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D3C60_16795	COG0140	phosphoribosyl-ATP diphosphatase activity
D3C60_16820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3C60_16835	COG4990	cell redox homeostasis
D3C60_16840	COG0110	maltose O-acetyltransferase activity
D3C60_16860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3C60_16875	COG1309	transcriptional regulator
D3C60_16880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3C60_16885	COG1950	PFAM Membrane protein of
D3C60_16890	COG1983	PspC domain protein
D3C60_16895	COG3595	metallopeptidase activity
D3C60_16910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3C60_16920	COG4897	Protein conserved in bacteria
D3C60_16925	COG0574	Belongs to the PEP-utilizing enzyme family
D3C60_16925	COG3848	Pyruvate phosphate dikinase
D3C60_16930	COG1309	transcriptional regulator
D3C60_16935	COG2814	Major facilitator Superfamily
D3C60_16950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3C60_16960	COG0793	Belongs to the peptidase S41A family
D3C60_16960	COG3409	Peptidoglycan-binding domain 1 protein
D3C60_16965	COG3420	alginic acid biosynthetic process
D3C60_16970	COG2177	Part of the ABC transporter FtsEX involved in
D3C60_16975	COG2884	Cell division ATP-binding protein ftsE
D3C60_16980	COG2010	Cytochrome c
D3C60_16985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3C60_17000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3C60_17015	COG1516	flagellar protein fliS
D3C60_17020	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D3C60_17025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3C60_17045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3C60_17050	COG4786	Flagellar basal body rod
D3C60_17050	COG1256	bacterial-type flagellum assembly
D3C60_17055	COG3418	PFAM FlgN family protein
D3C60_17060	COG2747	anti-sigma28 factor FlgM
D3C60_17070	COG1040	competence protein
D3C60_17080	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D3C60_17085	COG1307	EDD domain protein, DegV family
D3C60_17090	COG2197	response regulator
D3C60_17095	COG4585	Histidine kinase
D3C60_17100	COG1739	Uncharacterized protein family UPF0029
D3C60_17105	COG1316	TRANSCRIPTIONal
D3C60_17110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3C60_17115	COG0438	transferase activity, transferring glycosyl groups
D3C60_17120	COG1215	transferase activity, transferring glycosyl groups
D3C60_17125	COG3206	protein involved in exopolysaccharide biosynthesis
D3C60_17130	COG3307	-O-antigen
D3C60_17135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3C60_17140	COG0438	transferase activity, transferring glycosyl groups
D3C60_17140	COG0297	glycogen (starch) synthase activity
D3C60_17145	COG2244	polysaccharide biosynthetic process
D3C60_17155	COG2247	cell wall binding repeat
D3C60_17155	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3C60_17160	COG2385	sporulation resulting in formation of a cellular spore
D3C60_17160	COG2247	cell wall binding repeat
D3C60_17170	COG1316	TRANSCRIPTIONal
D3C60_17180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D3C60_17185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3C60_17190	COG1134	teichoic acid transport
D3C60_17195	COG1682	transport, permease protein
D3C60_17200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3C60_17210	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D3C60_17215	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D3C60_17220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3C60_17225	COG4193	domain, Protein
D3C60_17230	COG1482	cell wall glycoprotein biosynthetic process
D3C60_17235	COG0697	spore germination
D3C60_17240	COG0814	amino acid
D3C60_17250	COG1215	transferase activity, transferring glycosyl groups
D3C60_17255	COG2814	Major facilitator Superfamily
D3C60_17260	COG1316	TRANSCRIPTIONal
D3C60_17265	COG0561	phosphatase activity
D3C60_17270	COG2433	Pfam Transposase IS66
D3C60_17275	COG0791	NLP P60 protein
D3C60_17285	COG2843	Capsule synthesis protein
D3C60_17295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3C60_17305	COG0697	spore germination
D3C60_17310	COG0814	amino acid
D3C60_17320	COG1609	Transcriptional regulator
D3C60_17325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3C60_17335	COG1129	ABC transporter
D3C60_17340	COG1172	Belongs to the binding-protein-dependent transport system permease family
D3C60_17345	COG1879	ABC-type sugar transport system periplasmic component
D3C60_17350	COG3103	Sh3 type 3 domain protein
D3C60_17355	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3C60_17360	COG3527	Alpha-acetolactate decarboxylase
D3C60_17365	COG0028	Belongs to the TPP enzyme family
D3C60_17370	COG0583	DNA-binding transcription factor activity
D3C60_17375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3C60_17390	COG5337	Spore coat protein CotH
D3C60_17400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3C60_17410	COG0405	Gamma-glutamyltransferase
D3C60_17415	COG1522	sequence-specific DNA binding
D3C60_17420	COG2059	Chromate
D3C60_17425	COG2059	Chromate
D3C60_17475	COG5444	nuclease activity
D3C60_17490	COG3878	Protein conserved in bacteria
D3C60_17495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D3C60_17500	COG4464	protein tyrosine phosphatase activity
D3C60_17505	COG0489	protein tyrosine kinase activity
D3C60_17510	COG3944	biosynthesis protein
D3C60_17525	COG4715	Zinc finger, swim domain protein
D3C60_17530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3C60_17535	COG0561	phosphatase activity
D3C60_17540	COG1349	DNA-binding transcription factor activity
D3C60_17545	COG0629	single-stranded DNA binding
D3C60_17570	COG0457	Tetratricopeptide repeat
D3C60_17575	COG4786	Flagellar basal body rod
D3C60_17580	COG4786	Flagellar basal body rod
D3C60_17585	COG1077	Cell shape determining protein MreB Mrl
D3C60_17590	COG1609	Transcriptional regulator
D3C60_17595	COG1846	Transcriptional regulator
D3C60_17600	COG2814	Major facilitator Superfamily
D3C60_17605	COG1953	Uracil, thiamine, allantoin
D3C60_17610	COG0477	Major facilitator Superfamily
D3C60_17615	COG1335	isochorismatase
D3C60_17620	COG0004	ammonium transporteR
D3C60_17625	COG0347	Belongs to the P(II) protein family
D3C60_17630	COG0772	Belongs to the SEDS family
D3C60_17635	COG0671	phosphoesterase, PA-phosphatase related
D3C60_17645	COG0739	heme binding
D3C60_17650	COG1247	-acetyltransferase
D3C60_17665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3C60_17680	COG0726	polysaccharide deacetylase
D3C60_17690	COG1959	2 iron, 2 sulfur cluster binding
D3C60_17705	COG0831	urea catabolic process
D3C60_17710	COG3237	CsbD-like
D3C60_17715	COG1994	Peptidase M50
D3C60_17720	COG0457	Tetratricopeptide repeat
D3C60_17730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3C60_17735	COG2304	oxidoreductase activity
D3C60_17740	COG2304	oxidoreductase activity
D3C60_17750	COG2385	sporulation resulting in formation of a cellular spore
D3C60_17755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3C60_17765	COG4836	Membrane
D3C60_17805	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3C60_17835	COG0698	ribose 5-phosphate isomerase
D3C60_17840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D3C60_17850	COG0009	L-threonylcarbamoyladenylate synthase
D3C60_17855	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D3C60_17875	COG2890	protein-(glutamine-N5) methyltransferase activity
D3C60_17880	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D3C60_17885	COG0346	lactoylglutathione lyase activity
D3C60_17890	COG0789	Transcriptional regulator
D3C60_17895	COG0679	Auxin Efflux Carrier
D3C60_17900	COG0281	malic enzyme
D3C60_17910	COG0254	rRNA binding
D3C60_17915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D3C60_17920	COG1494	fructose-1,6-bisphosphatase
D3C60_17925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3C60_17940	COG0191	fructose-bisphosphate aldolase activity
D3C60_17945	COG2204	response regulator
D3C60_17950	COG4821	SIS domain
D3C60_17965	COG0247	lactate metabolic process
D3C60_17965	COG2181	nitrate reductase activity
D3C60_17970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3C60_17985	COG1132	(ABC) transporter
D3C60_17990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3C60_18000	COG2181	nitrate reductase activity
D3C60_18005	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D3C60_18010	COG1140	nitrate reductase beta subunit
D3C60_18015	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D3C60_18020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3C60_18030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3C60_18035	COG2223	nitrite transmembrane transporter activity
D3C60_18045	COG4506	Protein conserved in bacteria
D3C60_18055	COG3391	amine dehydrogenase activity
D3C60_18060	COG3391	amine dehydrogenase activity
D3C60_18070	COG0457	Tetratricopeptide repeat
D3C60_18115	COG0010	Belongs to the arginase family
D3C60_18120	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D3C60_18125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3C60_18140	COG1994	Peptidase M50
D3C60_18145	COG1942	4-Oxalocrotonate Tautomerase
D3C60_18150	COG1846	Transcriptional regulator
D3C60_18160	COG0531	amino acid
D3C60_18165	COG3465	dGTPase activity
D3C60_18170	COG1078	dGTPase activity
D3C60_18185	COG1695	Transcriptional regulator
D3C60_18195	COG1131	(ABC) transporter
D3C60_18200	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D3C60_18230	COG0583	DNA-binding transcription factor activity
D3C60_18235	COG2855	membrane
D3C60_18240	COG0280	phosphate acetyltransferase
D3C60_18250	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_18255	COG0436	Aminotransferase
D3C60_18285	COG2814	Major facilitator Superfamily
D3C60_18290	COG2814	Major facilitator Superfamily
D3C60_18295	COG0833	amino acid
D3C60_18300	COG4187	Peptidase family M20/M25/M40
D3C60_18305	COG1012	belongs to the aldehyde dehydrogenase family
D3C60_18310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D3C60_18320	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
D3C60_18325	COG1091	dTDP-4-dehydrorhamnose reductase activity
D3C60_18330	COG1088	dTDP-glucose 4,6-dehydratase activity
D3C60_18335	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D3C60_18340	COG3980	spore coat polysaccharide biosynthesis protein
D3C60_18345	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
D3C60_18350	COG2089	acid synthase
D3C60_18355	COG0456	acetyltransferase
D3C60_18360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3C60_18365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D3C60_18370	COG0463	Glycosyl transferase, family 2
D3C60_18380	COG2363	Small membrane protein
D3C60_18385	COG2233	PERMEase
D3C60_18400	COG1216	Glycosyl transferase, family 2
D3C60_18415	COG1695	Transcriptional regulator
D3C60_18420	COG0351	phosphomethylpyrimidine kinase
D3C60_18430	COG1621	beta-fructofuranosidase activity
D3C60_18435	COG1263	PTS System
D3C60_18435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3C60_18440	COG3711	transcriptional antiterminator
D3C60_18450	COG1404	Belongs to the peptidase S8 family
D3C60_18455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D3C60_18465	COG0778	Nitroreductase
D3C60_18470	COG0772	Belongs to the SEDS family
D3C60_18475	COG0454	-acetyltransferase
D3C60_18495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3C60_18500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3C60_18505	COG2261	transglycosylase associated protein
D3C60_18510	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D3C60_18515	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D3C60_18520	COG2246	polysaccharide biosynthetic process
D3C60_18525	COG1309	transcriptional regulator
D3C60_18545	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D3C60_18550	COG2837	iron assimilation
D3C60_18565	COG0583	DNA-binding transcription factor activity
D3C60_18575	COG1346	cytolysis
D3C60_18580	COG4895	conserved protein (DUF2196)
D3C60_18585	COG0789	Transcriptional regulator
D3C60_18590	COG5504	Zn-dependent protease
D3C60_18595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D3C60_18600	COG0346	lactoylglutathione lyase activity
D3C60_18605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3C60_18610	COG1404	Belongs to the peptidase S8 family
D3C60_18615	COG1442	glycosyl transferase family 8
D3C60_18620	COG2357	RelA SpoT domain protein
D3C60_18625	COG1575	Belongs to the MenA family. Type 1 subfamily
D3C60_18645	COG1696	Membrane protein involved in D-alanine export
D3C60_18655	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D3C60_18660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3C60_18665	COG1486	melibiose metabolic process
D3C60_18670	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3C60_18675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3C60_18680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3C60_18685	COG3711	transcriptional antiterminator
D3C60_18685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3C60_18700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_18705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3C60_18715	COG0640	Transcriptional regulator
D3C60_18720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D3C60_18725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3C60_18730	COG1447	Phosphotransferase system cellobiose-specific component IIA
D3C60_18735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D3C60_18740	COG2723	6-phospho-beta-galactosidase activity
D3C60_18745	COG1940	carbohydrate kinase activity
D3C60_18750	COG1482	cell wall glycoprotein biosynthetic process
D3C60_18760	COG0753	catalase activity
D3C60_18765	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D3C60_18770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D3C60_18775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D3C60_18780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D3C60_18785	COG4988	ABC transporter
D3C60_18790	COG1294	oxidase, subunit
D3C60_18795	COG1271	oxidase subunit
D3C60_18800	COG3493	citrate carrier protein
D3C60_18805	COG0726	polysaccharide deacetylase
D3C60_18810	COG3842	ATPase activity
D3C60_18815	COG2508	Transcriptional regulator
D3C60_18820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3C60_18830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D3C60_18840	COG4894	glucomannan catabolic process
D3C60_18845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3C60_18850	COG0500	methyltransferase
D3C60_18855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3C60_18870	COG0693	protein deglycase activity
D3C60_18870	COG0753	catalase activity
D3C60_18875	COG2851	Citrate transporter
D3C60_18880	COG2273	Hydrolase Family 16
D3C60_18885	COG3711	transcriptional antiterminator
D3C60_18890	COG2270	Major facilitator Superfamily
D3C60_18895	COG0513	Belongs to the DEAD box helicase family
D3C60_18935	COG3209	COG3209 Rhs family protein
D3C60_18945	COG0697	spore germination
D3C60_18955	COG2723	6-phospho-beta-galactosidase activity
D3C60_18960	COG1263	PTS System
D3C60_18960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3C60_18960	COG2190	(PTS) system
D3C60_18975	COG0494	nUDIX hydrolase
D3C60_18980	COG3507	Belongs to the glycosyl hydrolase 43 family
D3C60_19005	COG0010	Belongs to the arginase family
D3C60_19010	COG0833	amino acid
D3C60_19015	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D3C60_19020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3C60_19030	COG2390	Transcriptional regulator
D3C60_19035	COG0561	phosphatase activity
D3C60_19065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D3C60_19070	COG5294	Protein conserved in bacteria
D3C60_19075	COG0577	efflux transmembrane transporter activity
D3C60_19080	COG1136	(ABC) transporter
D3C60_19085	COG2205	protein histidine kinase activity
D3C60_19090	COG0745	RESPONSE REGULATOR receiver
D3C60_19105	COG1082	Xylose isomerase domain protein TIM barrel
D3C60_19115	COG2814	Major facilitator Superfamily
D3C60_19145	COG1349	DNA-binding transcription factor activity
D3C60_19150	COG0667	Aldo Keto reductase
D3C60_19155	COG2814	Major facilitator Superfamily
D3C60_19170	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_19175	COG2197	response regulator
D3C60_19180	COG4585	Histidine kinase
D3C60_19185	COG3239	Fatty acid desaturase
D3C60_19195	COG1309	transcriptional regulator
D3C60_19200	COG1012	belongs to the aldehyde dehydrogenase family
D3C60_19205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3C60_19215	COG0640	Transcriptional regulator
D3C60_19220	COG2814	Major facilitator Superfamily
D3C60_19225	COG1714	RDD family
D3C60_19235	COG0450	alkyl hydroperoxide reductase
D3C60_19240	COG3634	alkyl hydroperoxide reductase activity
D3C60_19245	COG3177	Filamentation induced by cAMP protein fic
D3C60_19250	COG1113	amino acid transport
D3C60_19260	COG2080	2 iron, 2 sulfur cluster binding
D3C60_19275	COG2068	MobA-Related Protein
D3C60_19280	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D3C60_19340	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
D3C60_19345	COG0667	Aldo Keto reductase
D3C60_19350	COG0456	acetyltransferase
D3C60_19355	COG0457	Tetratricopeptide repeat
D3C60_19360	COG0010	Belongs to the arginase family
D3C60_19365	COG0833	amino acid
D3C60_19370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3C60_19375	COG5658	integral membrane protein
D3C60_19380	COG0640	Transcriptional regulator
D3C60_19385	COG3829	transcription factor binding
D3C60_19395	COG0488	(ABC) transporter
D3C60_19410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3C60_19415	COG5002	protein histidine kinase activity
D3C60_19415	COG3850	Histidine kinase
D3C60_19420	COG0745	RESPONSE REGULATOR receiver
D3C60_19425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3C60_19430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D3C60_19435	COG4853	Protein conserved in bacteria
D3C60_19440	COG4863	YycH protein
D3C60_19445	COG5002	protein histidine kinase activity
D3C60_19450	COG0745	RESPONSE REGULATOR receiver
D3C60_19485	COG0346	lactoylglutathione lyase activity
D3C60_19490	COG0305	Participates in initiation and elongation during chromosome replication
D3C60_19510	COG3093	addiction module antidote protein HigA
D3C60_19515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D3C60_19530	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D3C60_19535	COG0438	transferase activity, transferring glycosyl groups
D3C60_19555	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D3C60_19560	COG4241	membrane
D3C60_19570	COG5577	PFAM Coat F domain
D3C60_19575	COG1733	regulation of RNA biosynthetic process
D3C60_19590	COG0697	spore germination
D3C60_19595	COG1621	beta-fructofuranosidase activity
D3C60_19600	COG1621	beta-fructofuranosidase activity
D3C60_19605	COG1802	Transcriptional regulator
D3C60_19610	COG2318	DinB family
D3C60_19615	COG2211	Major facilitator Superfamily
D3C60_19620	COG0583	DNA-binding transcription factor activity
D3C60_19635	COG0778	Nitroreductase
D3C60_19640	COG1846	Transcriptional regulator
D3C60_19645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D3C60_19650	COG1846	Transcriptional regulator
D3C60_19655	COG2153	protein acetylation
D3C60_19665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D3C60_19670	COG0583	DNA-binding transcription factor activity
D3C60_19675	COG1028	Short-chain dehydrogenase reductase Sdr
D3C60_19680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3C60_19685	COG0697	spore germination
D3C60_19690	COG1331	Highly conserved protein containing a thioredoxin domain
D3C60_19700	COG1078	dGTPase activity
D3C60_19715	COG1331	Highly conserved protein containing a thioredoxin domain
D3C60_19720	COG1266	CAAX protease self-immunity
D3C60_19725	COG0477	Major facilitator Superfamily
D3C60_19725	COG2814	Major facilitator Superfamily
D3C60_19730	COG0346	lactoylglutathione lyase activity
D3C60_19735	COG1609	Transcriptional regulator
D3C60_19740	COG0708	Exodeoxyribonuclease III
D3C60_19745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3C60_19750	COG2169	Transcriptional regulator
D3C60_19760	COG0629	single-stranded DNA binding
D3C60_19770	COG0012	GTP binding
D3C60_19775	COG0243	molybdopterin cofactor binding
D3C60_19780	COG4481	Protein conserved in bacteria
D3C60_19785	COG3949	Membrane
D3C60_19800	COG1475	DNA binding
D3C60_19805	COG1192	Involved in chromosome partitioning
D3C60_19830	COG1847	R3H domain protein
D3C60_19835	COG0706	membrane insertase activity
D3C60_19845	COG0230	Belongs to the bacterial ribosomal protein bL34 family